Gene PTPN6-1 in Strongylocentrotus purpuratus

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family PTP
Subfamily PTPN6
Protein sequence
ID Type Fasta BLAST phosphatome Note
SpurP063_AA protein Get Run
SpurP063_AA_194-353 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_PTPN6_pd Subfamily PTPN6 195-345 4.8e-58 191.5 In-house 52-182 (306) alignment
Range on Protein: 195-345
Range on HMM: 52-182/306.0
SDWMCKDCIICIFPFiDHSRVII-NDGLPG-DYINGNYIDlpKAWKNSielqqqgenvekidmswehQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMT
 ....|... .|.|| ||.|||. ....|| ||||.|||.  |..|.|                   .|.||||||||..||..|||..|||||||||||
penkeknryknilPf.Dhtrvilkepsvpgsdyinanyik..kevkgs...................dksyiatqgclettvsdFWrmvwqensrvivmt

TKEVERGKNKCCRYWPDANTKKDTGVITVTHISEQSMADYDLREFSMSHKDFN
||||||||.||.|||||...|...|.|.||..||.|.|||.|||.|.|.|...
tkevErgkekCarYWPdeeekeeyGkisvtnvseksladYilRelsvskkkkk

0049772 (Phosphotyrosine protein) phosphatases II 195-309 7.9e-09 31.1 In-house 44-156 (314) alignment
Range on Protein: 195-309
Range on HMM: 44-156/314.0
SDWMCKDCIICIFPFIdhSRVIInDGLPG---DYINGNYIDLPkawknsielqqqgenvekidmswehqKRYIATQGCLKDTVPEF----------WRVA
   . |.  . |.|.   .|||. .|||.   |||| .|.| .                          ...||||| |. ||  |          ||. 
flnrdknryldilpad..nrvil.pglpvsgsdyinasyvdgf..........................lkfIatqgpleitvvdfreepvlyyngwrmv

--WQENSRVIVM---------------------TTKEVERGknkccrywpD
  .. |.|.|||                      ..  ..|         .
lrgdlnvrdivmsrdevladelsrLdaAlgKtpllildgng.........n

0047943 (Phosphotyrosine protein) phosphatases II 198-344 6.4e-34 113.1 In-house 39-162 (273) alignment
Range on Protein: 198-344
Range on HMM: 39-162/273.0
MCKDCIICIFPFiDHSRVIInDGLPGDYINGNYIDLPkawknsielqqqgenvekidmswEHQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVE
. |. .  |.|. |||||.. .. . |||| .|.|..                       ......||||| |..|| .|||  |..|.||||| |..||
kdknrykdilpy.dhsrvkl.gdggsdyinAsyvdgy.......................nlkrkfiatqgPlpntvedfwrmvweqnvrviVmLtelve

RGKNKCCRYWPDANT--KKDTGVITVTHISEQSMADYDLREFSMSHKDF
.|..||..|||. .   ..  | .|||..||.. .|| .|.. ......
lgrekcaqYwpleggelsltygkftvtllseetkddytvrtleltnlgt

subfamily_Cele-PTP-8_pd Subfamily Cele-PTP-8 198-314 1.8e-08 28.8 In-house 44-135 (288) alignment
Range on Protein: 198-314
Range on HMM: 44-135/288.0
MCKDCIICIfPFIDHSRVIINDGlPGDYINGNYIDlpkawknsielqqqgenvekidmSWEHQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVE
 ..|    . |  | .|| ..|  |  ||. | .                        | ....| | .|  |. |. |.|..  ... . ||| .. .|
ptrdryenl.prcditrvklsdd.pdfyiaanvvs.......................sakykrrlicaqaPlngtieelWkmllesdveyivmlcelle

RGKNKCCRYWPDANTKK
.||.|   |.|    .|
kGkeksaeyfPsklGek

0039614 (Phosphotyrosine protein) phosphatases II 205-343 3.8e-29 97.5 In-house 63-180 (297) alignment
Range on Protein: 205-343
Range on HMM: 63-180/297.0
CIFPFIDHSRVIIND--G--LPGDYINGNYIDLPKAwknsielqqqgenvekidmsweHQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGK
  ..  |||||....  |  |. |||| .|.| ..                       .....|||||.|..||  |||  |.....|||| ||.||.|.
kdilpydhsrvklkpedgvdldsdYinAsyvdgydl......................ltrkfIatqgPlpetvedFwrmvweqgvtvivmLtklvelgr

nKCCRYWPDANTkkDTGVITVTHISEQSMADYDLREFSMSHKD
 ||..|||.  .    | .||| ....  ..| .|........
.kcaqywpeegg..tygdftvtllkvehldgytvrtlevtnng

subfamily_PTPN3_pd Subfamily PTPN3 206-342 3.1e-25 83.7 In-house 50-165 (280) alignment
Range on Protein: 206-342
Range on HMM: 50-165/280.0
IFPFiDHSRVIINDGLPgDYINGNYIDLpkawknsiELQqqgenvekidmSWEHQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCR
| |. |. ||.....   |||| ||...        |..           | .  .||||||| |..|. .||.. |...|..||| |  ||||. ||..
ilpy.datrvklkeset.dyinanyvnm........eip...........stglvnryiatqGPlaktatdfWqmvweqksslivmlttlverGrvkChq

YWPDANTKKDTGVITVTHISEQSMADYDLREFSMSHK
|||. . . . | ..|.  .|..   | |||. ...|
yWPetedeleygefsvkcekedetksyvlrelvlkdk

subfamily_Fungi-PTP1_pd Subfamily Fungi-PTP1 206-329 1.2e-18 61.9 In-house 56-172 (350) alignment
Range on Protein: 206-329
Range on HMM: 56-172/350.0
IFPFiDHSRVIINDG-----------LPGDYINGNYIDLPKAwKNSIELQQqgenvekidmswehqkRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTK
|.|. .||||... .            . |||| ||. |..    .|. .                 .|||||. |. || .|..|  . . .||.. |.
ilPY.ehsrvkLkkslkssdakkhslstnDYinanYlkltrf.sveinpdf................kYiatqaPlpstvddfykvillnkvkvilslts

EVERGKNKCCRYWPDANTKKDTGVITVTHISEQSM
.|| . .|| |||.. . .. |  .. .. .  ..
dvelnlekcyrYWqegsydditvklaskwenimgi

0036941 (Phosphotyrosine protein) phosphatases II 207-342 3.1e-32 107.5 In-house 48-162 (297) alignment
Range on Protein: 207-342
Range on HMM: 48-162/297.0
FPFIDHSRVIInDGLPGDYINGNYIDlpkawknsielqqqgenvekidmSWEHQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRY
..  ||.||.. |. . ||||..|.|                        .......|||||.|..|| .|||  |..|..|||| |..||.|..||..|
ilpydhtRVkl.ddegsdYinAsyvd.......................gydlkrkfIatqgPlpntvedFWrmvweqnvtvIvmltelvelgrekcaqy

WPDA-NTKKDTGVITVTHISEQS--MADYDLREFSMSHK
||.  .  .  | .||| .|...   .|| ||.. ....
wpleegesltygdftvtllsvevvllddytlrtlevtdt

0040438 (Phosphotyrosine protein) phosphatases II 207-342 3.3e-32 107.4 In-house 52-166 (317) alignment
Range on Protein: 207-342
Range on HMM: 52-166/317.0
FPFIDHSRVIINDGL---PGDYINGNYIDlpkawknsielqqqgenvekidmSWEHQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKC
..  |||||....     . |||| .|.|                        .......|||||.|..||  |||  |.....|||| |...|.|..||
ilpydhsRVkLsplggdldsdYInAsyvd.......................gpnlkrkfIatqgPlpntvedFwrmvweqgvtvivmLteleelgrekc

CRYWPDaNTKKDTGVITVTHISEQSMADYDLREFSMSHK
..|||. ....  | .|||..||. .|.. ||.. ....
aqYwpl.getltygdftvtllseeelagitlrtlevedl

0045450 (Phosphotyrosine protein) phosphatases II 207-343 1.2e-31 106.0 In-house 64-189 (307) alignment
Range on Protein: 207-343
Range on HMM: 64-189/307.0
FPFIDHSRVIINDGLP----GDYINGNYIDLPKAWknsielqqqgenvekIDMSWEHQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNK
..  ||.||....  .    .||||..|...|  .               .  .. .....|||||.|..|| .|||  |.....|||| |..||.|..|
ilpydhtRVklssldgsledsdYiNAsyvrvplll...............lldgydlkrkfIatqgPlpetvedFwrmlweqgvtvivmltelvelgrek

CCRYWPDANTKKDTGVITVTHISEQSMADYDLREFSMSHKD
|..|||| ....  | .||| .||. ...| .| . ....|
caqywPdegeeltygnftvtllseehldgytvrtlevtdld

0043336 (Phosphotyrosine protein) phosphatases II 207-342 1.9e-29 98.4 In-house 54-167 (278) alignment
Range on Protein: 207-342
Range on HMM: 54-167/278.0
FPFIDHSRVIIND---GLPGDYINGNYIDlpkawknsielqqqgenvekidmSWEHQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKC
..  |||||....    |. |||| .|.|                        .......|||||.|..||  |||  |......||| |..||.|..||
ilpydhsrvklsllggdldsdYinAsyvd.......................gynvprkfiatqgPlpetvedFwrmvwelgvttivmLtelvelgrvkc

CRYWPdaNTKKDTGVITVTHISEQSMADYDLREFSMSHK
..|||  .. .  | .||| ..|....|| .| . ....
aqYwp..ggsltygdftvtllkeehlddytvrtlevtnl

0040439 (Phosphotyrosine protein) phosphatases II 207-342 3.5e-28 94.3 In-house 20-134 (249) alignment
Range on Protein: 207-342
Range on HMM: 20-134/249.0
FPFIDHSRVII---NDGLPGDYINGNYIDlpkawknsielqqqgenvekidmSWEHQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKC
..  |||||..   ... ..|||| .|||                        . ...|.|||||.|..||. |||  |.....|||| |..||.|..||
ilpydhsrvklsilpglflsdyinAsyid.......................gyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekc

CRYWPDaNTKKDTGVITVTHISEQSMADYDLREFSMSHK
..|||. .. .  | .||| .|.....|| .|.. ....
aqywpl.ggsleygdftvtllsvevkddytvrtleltnl

0050432 (Phosphotyrosine protein) phosphatases II 208-342 1.4e-34 115.2 In-house 78-191 (308) alignment
Range on Protein: 208-342
Range on HMM: 78-191/308.0
PFIDHSRVIIndGLPGDYINGNYIDLPKawknsielqqqgenvekidmsWEHQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRYW
.  |||||..  . . |||| .|.|..                      . .....|||||.|..||  |||  |..|.||||| ||.||.|..||..||
lpydhsRVkl..degsdYInAsyvdgys.....................sklprkfIatqgPlpntvedFwrmvweqnvrvIvmLtklvengrekcaqYw

PDA--NTKKDTGVITVTHISEQSMADYDLREFSMSHK
|.   .. .  | .|||..||....|| .|.. ....
plelgggsleygkftvtllseevlddytvrtleltnl

0046845 (Phosphotyrosine protein) phosphatases II 208-343 1.1e-33 112.3 In-house 38-159 (284) alignment
Range on Protein: 208-343
Range on HMM: 38-159/284.0
PFIDHSRVIINDGLP----GDYINGNYIDLPKAWKNsielqqqgenvekidmswEHQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKC
.  |||||...   .    .|||| .|.| .                        ..|..||||| |..|| .|||. |..|.||||| |..||.|..||
lpydhsRVklksldgdledsdYinAsyvdgydldlt..................yikkkfIatqgPlpntvedFwrmvweqnvrvIVmltelvengrekc

CRYWPDANTKKDTGVITVTHISEQSMADYDLREFSMSHKD
..|||. ....  | .||| .||. . || .|........
aqYwplegevltygdftvtllseevkddytvrtleltnlg

0051299 (Phosphotyrosine protein) phosphatases II 208-342 5.1e-33 110.2 In-house 59-172 (288) alignment
Range on Protein: 208-342
Range on HMM: 59-172/288.0
PFIDHSRVIINDG---LPGDYINGNYIDLPKAWknsielqqqgenvekidmswehqKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCC
.  |||||....     ..|||| .|||...                         ...|||||.|..|| .|||  |..|.||||| ||.||.|..||.
lpydhsRVkLsvldgvegsdYinAsyidgynlk.......................rkfIatqgPlpntvedFWrmvweqnvrvIvmltklvelgrekca

RYWPDaNTKKDTGVITVTHISEQSMADYDLREFSMSHK
.|||. ....  | |||| .||....|| .|.. ....
qYwpl.ggsltygditvtllseevlddytvrtlevtnl

Y_phosphatase Protein-tyrosine phosphatase 208-345 1.3e-30 102.0 Pfam-A 11-129 (235) alignment
Range on Protein: 208-345
Range on HMM: 11-129/235.0
PFIDHSRVII-NDGLPGDYINGNYIdlpkawknsielqqqgenvekidMSWEHQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRY
. .|..|| . ... | |||| ||.                       ......|..|||||.||.|. .|||. |||...|||| |...|.|..|| .|
lpydktrvklkgsegpsdYInAnyv.......................kgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqY

WP-DANTKKDTGVITVTHI-SEQ-SMADYDLREFSMSHKDFN
|| . .... .| |.|.   .|.  ...| ||......|. .
wpeeeeesltygdikvelkekekedekeytlrklelkkkkee

Y_phosphatase Protein-tyrosine phosphatase 208-345 1.3e-30 102.0 In-house 11-129 (235) alignment
Range on Protein: 208-345
Range on HMM: 11-129/235.0
PFIDHSRVII-NDGLPGDYINGNYIdlpkawknsielqqqgenvekidMSWEHQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRY
. .|..|| . ... | |||| ||.                       ......|..|||||.||.|. .|||. |||...|||| |...|.|..|| .|
lpydktrvklkgsegpsdYInAnyv.......................kgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqY

WP-DANTKKDTGVITVTHI-SEQ-SMADYDLREFSMSHKDFN
|| . .... .| |.|.   .|.  ...| ||......|. .
wpeeeeesltygdikvelkekekedekeytlrklelkkkkee

0042113 (Phosphotyrosine protein) phosphatases II 208-341 1.4e-26 88.9 In-house 19-131 (245) alignment
Range on Protein: 208-341
Range on HMM: 19-131/245.0
PFIDHSRVIINDGL---PGDYINGNYIDlpkawknsielqqqgenvekidmSWEHQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCC
.  ||.||....       |||| .|.|                         .. ...||||| |..||. |||  |......||| |.|.|.|..||.
lpydhtrvklspdggdldsdyinasyvd.......................gyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkca

RYWPDaNTKKDTGVITVTHISEQSMADYDLREFSMSH
.|||. .... .| .||| .||....|| .|......
qywpl.gesltygdftvtllseehlddytvrtlevtn

0037934 (Phosphotyrosine protein) phosphatases II 208-343 1.6e-26 88.7 In-house 20-127 (243) alignment
Range on Protein: 208-343
Range on HMM: 20-127/243.0
PFIDHSRVIINDglpGDYINGNYIDLPKawknsielqqqgenvekidmswehqkRYIATQGCLKDTVPE----FWRVAWQENSRVIVMTTKEVERGKNKC
.  |||||....   .||||.|.|. ..                          |.||||| |..|| .    |||  |.....|||| |..||.|..||
lpydhsrvkleg...sdyinanliyvtp..........................rliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekc

CRYWPdaNTKkDTGVITVTHISEQSMADYDLREFSMSHKD
..|||  ...   | .||| .||....|| .|.......|
aqywp..gev.tygdftvtllseehlddytvrtlllenld

subfamily_Cele-PTP-1_pd Subfamily Cele-PTP-1 208-341 7.9e-06 20.2 In-house 28-152 (290) alignment
Range on Protein: 208-341
Range on HMM: 28-152/290.0
PFIDHSRVIIND---GLPGDYINGNYIDLPKAWKNSIELQQQGENvekidmswehqkryiatQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKN---
|.. ..||....    .  |||  |..  |.  .  .    | ..                     . |. .|| .| ||... .||. .  |. .|   
pLveatrvvLkgygkrfnddyiHAnrvtcpnglrliltqsPqeki.................tekrnStiekfwwmakqEkvkqvVmlcefeeksantsl

-KCCRYWPDANT-KKDTGVITVTHISEQSMADYDLREFSMSH
  | .| |..   .   . .||   |     | . ||  . .
faCakYvpesvgeelkfkgltvkCkskekeddvetRelvvkf

DSPc_SM00195 209-343 5.7e-33 109.7 In-house 37-153 (263) alignment
Range on Protein: 209-343
Range on HMM: 37-153/263.0
FIDHSRVIINDGL---PGDYINGNYIDLPkawknsielqqqgenvekidmswEHQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCR
 .||.||....     . |||| |||...                       ...|.||||||.|..|| .|||. |.|....|||.|.|.|.||.|| |
pydhtrVklkkeekkegsdYINAnyikga.......................nkkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengkekcdr

YWPDA-NTKKDTGVITVTHISEQSMA-DYDLREFSMSHKD
|||.  ..|.. | |.|. ......  .. ||........
ywpeesggketfgkisvklvevekkkdeiilrtleltkeg

PTPc_SM00194 209-343 5.7e-33 109.7 In-house 37-153 (263) alignment
Range on Protein: 209-343
Range on HMM: 37-153/263.0
FIDHSRVIINDGL---PGDYINGNYIDLPkawknsielqqqgenvekidmswEHQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCR
 .||.||....     . |||| |||...                       ...|.||||||.|..|| .|||. |.|....|||.|.|.|.||.|| |
pydhtrVklkkeekkegsdYINAnyikga.......................nkkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengkekcdr

YWPDA-NTKKDTGVITVTHISEQSMA-DYDLREFSMSHKD
|||.  ..|.. | |.|. ......  .. ||........
ywpeesggketfgkisvklvevekkkdeiilrtleltkeg

0045098 (Phosphotyrosine protein) phosphatases II 209-342 1.3e-29 98.9 In-house 44-144 (278) alignment
Range on Protein: 209-342
Range on HMM: 44-144/278.0
FIDHSRVIindglpgDYINGNYIDLPkawKNsielqqqgenvekidmswehqkRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRYWP
 .|||||.       |||| .||| .   ..                      ..|||||.|..||  |||  |.....|||| |..||.|..||..|||
pydhsrVk.......dYINAsyidgy...pk......................kfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaqywp

DaNTKKDTGVITVTHISEQSMADYDLREFSMSHK
. .  .  | .||| .||. . || || . . . 
e.ggsltygdftvtllseevlddytlrtllvtnl

subfamily_Anemone-PTP-2_pd Subfamily Anemone-PTP-2 210-343 9.8e-23 75.8 In-house 68-180 (298) alignment
Range on Protein: 210-343
Range on HMM: 68-180/298.0
IDHSRVIIND---GLPGDYINGNYIDlpkawknsielqqqgenvekidmSWEHQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRY
.|.|||....      .||||  ...                       ...... .||||. |. || .|||. ..|.. .||| |. .| .| |. .|
ldssRvvLekedadeesdYiNAsflh.......................aykgrnafiatqaPltetvedFWrmvteedigtiVmltnleeldktkyhky

WPDANTKkDTGVITVTHISEQSMADYDLREFSMSHKD
||| ...   | |||.  |....||.  |.. .|.|.
wPdegke.tygeitvsllskeefadlivrklkvskkk

subfamily_Fungi-PTP2_pd Subfamily Fungi-PTP2 210-313 1.3e-12 41.7 In-house 77-159 (349) alignment
Range on Protein: 210-313
Range on HMM: 77-159/349.0
IDHSRVIINDGLPGDYINGNYIDLPKAWKNSielqqqgenvekidmswehqkRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRYWPD
|..|.   . | . |||| ||. |..   .                      .|||||  |  || .|..|   .. ....  ... | . .|| .|| .
ikastsesdsgklddyinanylkltrisvek.....................kyiatqaPlPstvddfykvillngvklvlsLnddkelslekcdiywqe

ANTK
 . .
lsys

subfamily_PTPRK_pd Subfamily PTPRK 211-341 3.1e-22 73.8 In-house 56-164 (314) alignment
Range on Protein: 211-341
Range on HMM: 56-164/314.0
DHSRVIIN---DGLPGDYINGNYIdlpkawknsielqqqgenvekidMSWEHQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRYW
|.|||..    .    ||||...|                        |... . .|.||| |..|| .|||. ..||.  ||| |. || |. ||..||
drsrvflitidgdpssdyinaali.......................dsykrpaafivtqgPlqetvkdfWrlvydencasivmltelvevgrvkClkyW

PDANTKkdTGVITVTHISEQSMADYDLREFSMSH
|.  ..   | | |. .. .  |..  | |....
Pedtev..ygdikvelvetellaelvvrifrvek

subfamily_Sponge-PTP5_pd Subfamily Sponge-PTP5 211-339 1.5e-19 65.0 In-house 46-152 (283) alignment
Range on Protein: 211-339
Range on HMM: 46-152/283.0
DHSRVIINdGLPGDYINGNYIDLpkawknsielqqqgenvekiDMSWEHQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRYWPDA
|  || ..  .. ||||  .| .                    . | ...|.||..|. |..|| .||.. ..|.   ||| ||  |  . ||..|||  
dqwrvelk.sesrdyinavfipv....................sksykqdkkyiiaqsPldrtvvdfWkmvfdekitaivmltklqedlrikCsqyWPkr

NTkKDTGVITVTHISEQSMADYDLREFSM
 . .| |  |||   | .   .  .|. .
Gs.edyGeftvtlrkettsnsfiikelll

0041856 (Phosphotyrosine protein) phosphatases II 214-318 4.8e-12 41.3 In-house 17-76 (182) alignment
Range on Protein: 214-318
Range on HMM: 17-76/182.0
RviindglPGDYINGNYIDlpkawknsielqqqgenvekidMSWEHQKrYIATQGCLKDTVPEFWRVAWQENSRVIVMTTkevergknkCCRYWPDANtk
|       . |||| |...                      .|. ... .||||| |..||..|.|  .... ..||. |         ...|||.    
r.......dldyInanlyl......................gslpatr.fiatqgpllstvadflrmlkelgittivnlt.........eelywpell..

kdtgV
     
....e

0046846 (Phosphotyrosine protein) phosphatases II 218-312 1.6e-12 43.0 In-house 7-74 (176) alignment
Range on Protein: 218-312
Range on HMM: 7-74/176.0
NDGLPGDYINGNYIDLPKawknsielqqqgenvekidmswehqkrYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRYWPDANT
 ..|. ||||.|.|. ..                           .||||| | .|...|..  .... ...|. |.||| |. ||..|||.  .
gldldldyinanlilgsr...........................piatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpelek

subfamily_Choan-PTP-2_pd Subfamily Choan-PTP-2 223-338 6.3e-21 69.6 In-house 48-144 (270) alignment
Range on Protein: 223-338
Range on HMM: 48-144/270.0
GDYINGNYIDlpkawknsielqqqgenvekiDMSWEhQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRYWPDANTK---KDTGVI
  ||| ||.                       .. | .|.|||..| |. |. .|||. |.|... |||||. .|.|..|| ||||  . .     .| |
taYinAnyvr.....................Gfdge.kkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkekvkledgki

TVTHISEQSMADYDLREFS
.|. .||. .  | |..  
kvlalseekeegyiltrlr

0051429 (Phosphotyrosine protein) phosphatases II 224-342 2.3e-15 52.5 In-house 5-113 (272) alignment
Range on Protein: 224-342
Range on HMM: 5-113/272.0
DYINGNYIDLPkawknsielqqqgenvekidMSWEHQKRYIATQGCLKDTVPEFWRVaWQENSRVIVMTTKEVERGKNKCCRYWP-----------DANT
.||| .... .                     ..   .|.....|.|. |. .|||  .... ..||. ..|.|||..|| ||||           |. .
gyiNardvggy....................grvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsap

KKDTGVITVTHISEQSMADYDLREFSMSHK
    | ..||..||. . || |||. ....
tilygalrvtllseellldyilrellltll

subfamily_Sponge-PTP9_pd Subfamily Sponge-PTP9 246-341 4.3e-19 63.3 In-house 71-166 (301) alignment
Range on Protein: 246-341
Range on HMM: 71-166/301.0
QGENVEKIDMsWEHQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRYWPDANTK-KDTGVITVTHISEQSMADYDLREFSMSH
.  | . ||    ..|..||.|| .| |. .|||. |||    ||| |.. |. |.|| .|||..... .. | .||| ..|| . |. .|....  
eyinasyidg.ysekkkfiaaqgpmkktlvdfWrliwqekpvsivmvtnlkegtkskceqywpnseaeseefgpftvtlvneqvyPdfvirqlnvki

0043147 (Phosphotyrosine protein) phosphatases II 248-311 7.1e-09 31.1 In-house 8-77 (172) alignment
Range on Protein: 248-311
Range on HMM: 8-77/172.0
ENVEKIDMSWeHQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKE-------VERGKNKCCRYWPDAN
.|.. .|... . .|.|||||.|  |...|||  .... ..||. |..       .. |   .. .||| .
inasyldlyy.ipdrfiatqgplrntladfwrmlkelgithivnltellydpellerlgiqylylpwpDhg

subfamily_ptpA1_pd Subfamily ptpA1 252-310 5.9e-14 46.6 In-house 82-138 (418) alignment
Range on Protein: 252-310
Range on HMM: 82-138/418.0
KIDMSweHQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRYWPDA
 || .  . |..|.||| | .|. .|||. |..  |.||| ..| |  . || ||||. 
yidga..ypkqfictqgplpntiadfwrmvwenrcriivmlsresencrikcdrywpeq

0036282 (Phosphotyrosine protein) phosphatases II 252-353 4.1e-12 41.6 In-house 9-79 (174) alignment
Range on Protein: 252-353
Range on HMM: 9-79/174.0
KIDMSWEHQkRYIATQGCLKdtvpeFWRVAWQENSRVIVMTTKEVERGKNKCCRYWPDantkkdtgvitvthiseqsmadydlREFSMSHKDFNKCCRYW
 .|.|.    |.||.||.|.     ||.  ........|| ..|.|.|. ||..|||.                         .  .... ... ..  |
pldlsyitp.rliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe.........................lredlerlgiqylylpw

PD
||
pD

subfamily_Choan-PTP-1_pd Subfamily Choan-PTP-1 253-342 3.2e-22 73.9 In-house 72-165 (281) alignment
Range on Protein: 253-342
Range on HMM: 72-165/281.0
IDMSW----EHQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRYWPDANTKKDTGVITVTHISEQSMADYDLREFSMSHK
|. ..    . .|.|||||| . ... .||.. |... ..||| |.|.| || || ||||| |..   | .||....|.. | |  |.|.....
inanfvpgykgekeyiatqgPvPaslvafWqmvweqkvsaivmvtreieagklkChrYWPddnselkygdvtvkstaeeekatyierkfklere

subfamily_Cele-PTP-15_pd Subfamily Cele-PTP-15 253-330 1.7e-09 32.1 In-house 67-147 (285) alignment
Range on Protein: 253-330
Range on HMM: 67-147/285.0
IDMSWEHQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRYWPDANT---KKDTGVITVTHISEQSMA
. |  . |  ||.||| | .|. .||.. .||.   ..|    .| | .||. |.|.      |     ||.|   |...|
mrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyypeklgevvkfgkyeitlteckeeaia

subfamily_PTPRG_pd Subfamily PTPRG 256-343 3.9e-24 79.8 In-house 86-172 (563) alignment
Range on Protein: 256-343
Range on HMM: 86-172/563.0
SWEHQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRYWPDaNTKKDTGVITVTHISEQSMADYDLREFSMSHKD
 ....| .||||| ||||.  |||. |..|. .||| |. ||||..|| .|||  .. .. |...|| |.|. .| |  |.... .  
GyqkskafiatqgplkdtfddFWrmiWeqnvaiivmitnlvergrrkcdvYWPk.desetygalqvtlieeevlalytvrtlviknlk

subfamily_Sponge-PTP8_pd Subfamily Sponge-PTP8 256-343 8.6e-23 75.9 In-house 84-172 (305) alignment
Range on Protein: 256-343
Range on HMM: 84-172/305.0
SWEHQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRYWPDANTK-KDTGVITVTHISEQSMADYDLREFSMSHKD
.....|.||..|| ||.|| .|||. ..|  ..||| || || ||.|| .|||.. |. |. | ..|.  ||....||  |....| .|
gykrkkkyivaqgPlkntvadfWrliveekvstivmltklveggkdkCrqYWpesktekkefgefsvelksektasdyieRklkisied

subfamily_Ptp69D_pd Subfamily Ptp69D 256-343 4.8e-21 70.2 In-house 86-172 (307) alignment
Range on Protein: 256-343
Range on HMM: 86-172/307.0
SWEHQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRYWPDAnTKKDTGVITVTHISEQSMADYDLREFSMSHKD
.....|..|| |. .  |. .|||. .. .. .||| ... |  ..|| .|||.  ...  | | |. .||... ||  ||...|.|.
gykekkkfiaaqdPveatigDfWRmiaeqevtlivmlsnlteknrkkcakYWpie.devqygdilvklvseekhsdyiiReldvskkk

subfamily_Anemone-PTP-5_pd Subfamily Anemone-PTP-5 256-342 5e-21 70.1 In-house 86-171 (319) alignment
Range on Protein: 256-342
Range on HMM: 86-171/319.0
SWEHQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRYWPDANTKkDTGVITVTHISEQSMADYDLREFSMSHK
........||||. |..|. .|||. |.|.| ..|| || ||..| |. .|||..| . . | ..||  .|. ..||  |.... .|
gyqerekfiatqaPlentiedfWrmvWeeessivvmltklveklkvklkkywpeenfe.eyGrlivtleeeeeledyiirklklnkk

subfamily_PTPN5_RR_pd Subfamily PTPN5_RR 256-342 5.5e-21 69.9 In-house 68-157 (274) alignment
Range on Protein: 256-342
Range on HMM: 68-157/274.0
SWEHQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRYWPDANTK---KDTGVITVTHISEQSMADYDLREFSMSHK
  |..| |.|||| |  || .|||. .||...||||.||  |. ..|| .|.|||.     .  | . ..  .  .  || .|...... 
ydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneqkCavyfPdaedyeiserygdveikvekiverndysvrklvlkyl

subfamily_Choan-PTP-3_pd Subfamily Choan-PTP-3 256-345 6.6e-19 62.8 In-house 75-165 (287) alignment
Range on Protein: 256-345
Range on HMM: 75-165/287.0
SWEHQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRYWPDANTKKDTGVITVTHISEQSM-ADYDLREFSMSHKDFN
|.......||.|| .  || .|||. ....| .... |.||| ...|| .|||. .     |  .|. .. . .  .|  | . . . . .
sytddeafiaaqgPiaatvrdfwravletrsasvitmtreveearlkcykywPerevPmrvGGysvvlldydikePeygvralrlidletr

subfamily_Sponge-PTP10_pd Subfamily Sponge-PTP10 256-342 4.8e-18 60.1 In-house 81-166 (287) alignment
Range on Protein: 256-342
Range on HMM: 81-166/287.0
SWEHQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRYWPDANTkKDTGVITVTHISEQSMADYDLREFSMSHK
.....|..|.... . .|. .||.. ...|  .||| ..| |  ...| .|||. ..    |  ... ..|. .|.|  |.. . .|
gykekkafiiaesPmfntarnfWkliddrnvtaivmlcqekendeevcyqyWpeeks.vvlGeyniellneevnagyierklevknk

subfamily_Urchin-PTP-6_pd Subfamily Urchin-PTP-6 256-342 1.3e-17 58.1 In-house 81-168 (515) alignment
Range on Protein: 256-342
Range on HMM: 81-168/515.0
SWEHQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRYWPD--ANTkKDTGVITVTHISEQSMADYDLREFSMSHK
| . .| |||.|| .| .| .|||. .|||   |.| ||  |  | || .||||  ...    | | |  .| .. ..   |.. . . 
sfdndkayiasqgPnkasvddfWrlvlqenvttiamvtklkegdkikcgkyWPdkpgds.vkfGsikvelvsleactggikrkltvlkg

subfamily_Urchin-PTP-1_pd Subfamily Urchin-PTP-1 256-340 1.4e-16 55.2 In-house 82-167 (315) alignment
Range on Protein: 256-340
Range on HMM: 82-167/315.0
SWEHQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRYWPD-ANTKKDTGVITVTHISEQSMADYDLREFSMS
| ...| |||.|| || .| .|||. .||.   ||| ||  |  | || .||||      . | | |. .| .. .|   |.. . 
svdddkayiasqgPlkasvddfwrmvlqekvttivmvtkkqegdkikcrqywPdrkadsvefGsikvellsleadtdgvarklvtr

subfamily_CG7180_pd Subfamily CG7180 256-341 4.6e-15 50.0 In-house 80-163 (296) alignment
Range on Protein: 256-341
Range on HMM: 80-163/296.0
SWEHQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKnKCCRYWPDANtKKDTGVITVTHISEQSMADYDLREFSMSH
|. ..| || |..  |.|| ||||. ..|..  .|. ||. .  | ..  |||    |.. | | |  ..|...|.   |.| . .
sflkkkeyivteapkketvdefWrlvydeeisavvvLtktfdfak.mypsywpnks.keqygeifveiveekqyanlkirtfkltk

subfamily_Urchin-PTP-4_pd Subfamily Urchin-PTP-4 256-319 1.3e-10 35.3 In-house 83-154 (392) alignment
Range on Protein: 256-319
Range on HMM: 83-154/392.0
SWEHQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTK--EVERGKN--KCCRY----WPDANTKKDTGVI
| . .| |||.||    .. .|||. .|||   |.| ||  | ..|..   ....    |||..  | |  .
sfdnekayiasqgpnaaslddfwrmvfqenvttiamvtklkegdkgddartvaqfhftewPdkdvpkhtssl

subfamily_Sponge-PTP1_pd Subfamily Sponge-PTP1 256-342 1.8e-08 28.7 In-house 67-151 (267) alignment
Range on Protein: 256-342
Range on HMM: 67-151/267.0
SWEHQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEverGKNKCCRYWPDA-NTKKDTGVITVTHISEQSMADYDLREFSMSHK
... .. .|.||. || |. .|. |  ...  |||. ||    ....  ..||      |    .|| |  |.   ||..  . .  |
gyktknafivtqdplkntitdfltvihdqkvpvivlltkv...ftdnirlfwPPkmgqakkyqdltvehslekeendyqiitlelkfk

subfamily_PTPRD_pd Subfamily PTPRD 257-342 3.1e-29 97.1 In-house 87-171 (564) alignment
Range on Protein: 257-342
Range on HMM: 87-171/564.0
WEHQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRYWPDANtKKDTGVITVTHISEQSMADYDLREFSMSHK
....| |||||| |..|. .|||  |..||..||| || .|.||.|| .|||. . ..  | .|||  .|. .||| .|.|....|
yrkrkayIAtqgPlaetiedFWRmvweqnsstiVmltkleEkgkvkchkYWPekg.tetygeltVtleeeeeladyeirtfklkkk

subfamily_PTPRB_pd Subfamily PTPRB 257-342 1.8e-26 87.9 In-house 90-175 (293) alignment
Range on Protein: 257-342
Range on HMM: 90-175/293.0
WEHQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRYWPDANTKKDTGVITVTHISEQSMADYDLREFSMSHK
 . .. .||||| | .|| .|||. |...|..||| |. ||.|| || .|||. ..    | |.|| ..|... |. .||......
ynsprefiatqGPlpetvddfWrmvwekkssiivmltqlvekgkvkCeeYWPadeepvlyGdikvtlvaeeeledwvirelkieke

subfamily_Anemone-PTP-6_pd Subfamily Anemone-PTP-6 257-343 3.2e-26 87.1 In-house 85-170 (318) alignment
Range on Protein: 257-343
Range on HMM: 85-170/318.0
WEHQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRYWPDANTKkDTGVITVTHISEQSMADYDLREFSMSHKD
....| |||.|. | .|...|||. |. ||.|||| |.|.||||.|. ||||. ...   | ..|.  .| ...|| ||||......
yrrkkayiaaqaPlpetieDfWrmvWeqnsavivmltqeeergkakvhryWPskgsr.sygklvvelkeevelsdyvlrefkvtrte

subfamily_PTPN9_pd Subfamily PTPN9 257-341 1.3e-24 81.8 In-house 81-166 (297) alignment
Range on Protein: 257-341
Range on HMM: 81-166/297.0
WEHQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRYWP-DANTKKDTGVITVTHISEQSMADYDLREFSMSH
....| .||||| || || .|||. |... .||||||. ||||. || .||| . .. .. | ..|.... ... ||  | . ...
ykqkkafiatqGplkktvsdfWrmvWeqevlvivmttrvvergrlkcgqyWpleeessaefgdlsvsnveveeeedykvrvleikn

subfamily_Sponge-PTP11_pd Subfamily Sponge-PTP11 257-342 2.2e-22 74.3 In-house 87-171 (290) alignment
Range on Protein: 257-342
Range on HMM: 87-171/290.0
WEHQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRYWPDANTKKdTGVITVTHISEQSMADYDLREFSMSHK
....|.|||||| ...|. .||.. |||.. .||| |...| ||.||  ||||..||.  | .... ..|... .|  |.... .|
ykekkqyiatqgpvsntlvdFWkliwqekvtiivmltniieegkvkCqqYWpdsdtka.ygefsikllneetlneyierklevknk

subfamily_Urchin-PTP-7_pd Subfamily Urchin-PTP-7 257-343 5.2e-20 66.6 In-house 88-172 (315) alignment
Range on Protein: 257-343
Range on HMM: 88-172/315.0
WEHQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRYWPDAntKKDTGVITVTHISEQSMADYDLREFSMSHKD
.....||||.|| .  .| .|||. ..|.   ||| |. ||. |.|. .||||   |   | ||||..||.   .|  | .|.  .|
ynkkrryiaaqgpnvasvkdfwrlvfeedigkivmltnlvegekrkaekywpdk..kviyGkitvtrkseevnteytvrtlsvvfgd

subfamily_Nvec-PTP-2_pd Subfamily Nvec-PTP-2 257-342 5.7e-20 66.6 In-house 48-131 (250) alignment
Range on Protein: 257-342
Range on HMM: 48-131/250.0
WEHQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNkCCRYWPDANTkKDTGVITVTHISEQSMADYDLREFSMSHK
.. .| .||||| |..|. .|||. ..|.| .||| |. .| .|. . .|||  .. .  | .||.  |.. .|||  |.. .|..
yderkafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqywPveka.ekyGdvtvsllskeefadytkrklklska

0044763 (Phosphotyrosine protein) phosphatases II 257-333 9.7e-08 27.4 In-house 25-90 (178) alignment
Range on Protein: 257-333
Range on HMM: 25-90/178.0
WEHQKRYIATQGClkdtvPEFWRVAWQENSRVIVMTTKEVERGKNKCCRYWPDANTkkdtgvITVTHISEQSMADYD
.     |......     .....  .... ..||. |.|.|.|..||..|||. .       |.. ||    . . |
eilpglylgslpp.....addlellkelgithivnlteelelgflkcdpywpeeag......iqylhipipDhgvpd

subfamily_Urchin-PTP-2_pd Subfamily Urchin-PTP-2 257-342 3.2e-07 24.0 In-house 232-314 (440) alignment
Range on Protein: 257-342
Range on HMM: 232-314/440.0
WEHQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVErgkNKCCRYWPDANTKKDTGVITVTHISEQSMADYDLREFSMSHK
. ... .||||  |  || .|||.  . .   |.|  .  .   . |  |||        | .|| |   . |    .| . . .|
yskknafiatqmpldstvldfwrlvhdyristiimlnqlnd...ktcsiywpvntrsvtfgpftvghkgsenmnrvkvrtlelkyk

subfamily_Urchin-PTPRB-like_pd Subfamily Urchin-PTPRB-like 258-342 1.8e-22 74.7 In-house 87-171 (288) alignment
Range on Protein: 258-342
Range on HMM: 87-171/288.0
EHQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRYWPDANTKKDTGVITVTHISEQSMADYDLREFSMSHK
...|.|||||| | ||| .||.. .....  ||| |. ||.||.|| .|||||...|  | .||| .... . |. ||.. . .|
kkkkkyiatqgPladtvndfWelvyenktstivmltelveggktkCeeYWPdadkpknyGsvtvtlveskeledfvlrklllekk

subfamily_PTPN12_pd Subfamily PTPN12 258-342 8.1e-22 72.4 In-house 80-166 (290) alignment
Range on Protein: 258-342
Range on HMM: 80-166/290.0
EHQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRYWPDANTKKD-TGVITVTHISEQSMA-DYDLREFSMSHK
| ...|||.|| | .|. .|||. |. | ...||  .||| ||.|| ||||. . ..  .| ..|| ..|. .  |. .| . . ..
egkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCerYWpeegeeelefgefevtleeekavdddflirtLkveaq

subfamily_PTPN13_pd Subfamily PTPN13 258-342 2.5e-19 64.6 In-house 74-160 (273) alignment
Range on Protein: 258-342
Range on HMM: 74-160/273.0
EHQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRYWPDANTKKDT--GVITVTHISEQSMADYDLREFSMSHK
... .|||.|| | .|| .||.. |. ...||.| |.|.|.|| || ||||. . || .  . ..|. .  | . .. .|.. ....
kdeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvkchrywPesknkklkvsnrlevellkvqkldgfvvralavkds

subfamily_PTPN1_pd Subfamily PTPN1 258-340 2.8e-19 63.9 In-house 68-154 (290) alignment
Range on Protein: 258-340
Range on HMM: 68-154/290.0
EHQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRYWPDANT----KKDTGVITVTHISEQSMADYDLREFSMS
| ...|| ||| | .||  ||.. |...|. .||  | ||....|| .|||  .     . .   ..|. |||..   | .| . . 
eakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvvekeqikcaqywPqgeeekellledtklkvkliseerksyytvrllele

subfamily_PTPRA_pd Subfamily PTPRA 258-340 3.1e-19 64.0 In-house 98-179 (330) alignment
Range on Protein: 258-340
Range on HMM: 98-179/330.0
EHQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRYWPDANTkKDTGVITVTHISEQSMADYDLREFSMS
......||.|| ...|| .|||. |. .|  ||| |.  || ..|| .||||  .    | |.|.   |. . || .|.| . 
kekdkfiaaqGPkeetvedfwrmiweqksativmltelkerkeekcaqywPdeGl.vtyGnirvevedetvlvdytvrkflvq

subfamily_Choan-PTP-4_pd Subfamily Choan-PTP-4 258-333 4.7e-17 56.8 In-house 73-148 (297) alignment
Range on Protein: 258-333
Range on HMM: 73-148/297.0
EHQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRYWPDANT-KKDTGVITVTHISEQSMAdYD
|.. .|| .|| |..|| .||.. .... ||||| .|  | |..||  |||...  .. .| . | ..|. |   .|
eadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrdkcapywpsvvqerlkagdvvveflsstsde.fd

subfamily_Urchin-PTPRA_pd Subfamily Urchin-PTPRA 258-342 2.1e-16 55.1 In-house 101-178 (319) alignment
Range on Protein: 258-342
Range on HMM: 101-178/319.0
EHQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTkevergKNKCCRYWPDA-NTKKDTGVITVTHISEQsmADYDLREFSMSHK
 ....|||.|| |..|. .|||. |. |.  ||. |      |.||..|||   . |.. . . |. . |   |.| .|.. .|..
qrkdkyiaaqGPldntladfWrmiweyncstivllt......kdkcsqywplkivikeerfkvkvdsveet..aeyvvrdielsed

subfamily_Urchin-PTP-8_pd Subfamily Urchin-PTP-8 258-342 2.2e-16 55.2 In-house 65-142 (284) alignment
Range on Protein: 258-342
Range on HMM: 65-142/284.0
EHQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTkevergKNKCCRYWPDA-NTKKDTGVITVTHISEQsmADYDLREFSMSHK
 ....|||||| |..|. .|||. |. |.  ||. |      |.||..|||   . |.. . . |. ..|   ..| .|.. .|..
qrkdkyiatqGPldntladfWrmiweyncstivllt......kdkcsqywplkivikeerfkvkvdsvees..eeyvvrdielsed

subfamily_Cele-PTP-19_pd Subfamily Cele-PTP-19 258-322 1.9e-10 35.0 In-house 87-152 (301) alignment
Range on Protein: 258-322
Range on HMM: 87-152/301.0
EHQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRYWPDANTK-KDTGVITVT
 | .|.||||| ||.|  .|| .  | .   ||| ...||. ..||  | |   ..  | |  ...
GhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkisekldigrfkik

subfamily_Anemone-PTP-4_pd Subfamily Anemone-PTP-4 259-342 3e-21 70.7 In-house 43-126 (237) alignment
Range on Protein: 259-342
Range on HMM: 43-126/237.0
HQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRYWPDANTKKDTGVITVTHISEQSMADYDLREFSMSHK
  |.|||.|| |. .  .||.. |||.  |||| |  .|. . || .|||...  .  ||.||.   .. ..|| .| . .|..
tpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpstdqpaaygvltvslkkkeefsdytvrslllskr

subfamily_PTPN14_pd Subfamily PTPN14 259-316 1.5e-16 55.3 In-house 91-148 (300) alignment
Range on Protein: 259-316
Range on HMM: 91-148/300.0
HQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRYWPDANTKKDT
... ||..|| |. || .||.. |... ..||| |.| | ||.|. .|.|. . ||.|
kersyivaqgPleltvqdfWqmvWeqgvqlivmlteeeedgkeksfkyfPkleskkkt

subfamily_Urchin-PTP-5_pd Subfamily Urchin-PTP-5 259-343 7.5e-16 53.1 In-house 90-172 (297) alignment
Range on Protein: 259-343
Range on HMM: 90-172/297.0
HQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKnKCCRYWPDANTKKdTGVITVTHISEQSMADYDLREFSMSHKD
 ..|.|.||   |.|| .||.. ..|.  .||| ... || | || |||.|  ...  | ..|.  | ..   .  ||..... .
nkhrlittqmPmkatvadfWamvldeqvstivmlnddnerdk.kcaryWsdkgvtt.fGdvsvvllsvsereGfikrelevtkgk

subfamily_PTPRN_pd Subfamily PTPRN 259-337 1.2e-14 48.8 In-house 98-176 (297) alignment
Range on Protein: 259-337
Range on HMM: 98-176/297.0
HQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRYWPDANTkKDTGVITVTHISEQSMA-DYDLREF
 .  |||||| | .|| .||.. |.. . |||. |.  | | ..| |||||  . .  ..  |  .||   . || .| |
rapayiatqgplastvadfwqmvweqGvvvivnltrleeegvkqckrywpdeGs.evyhiyevhlvsehiwcddylvrsf

subfamily_Urchin-PTP-3_pd Subfamily Urchin-PTP-3 259-339 6.4e-14 46.8 In-house 89-169 (325) alignment
Range on Protein: 259-339
Range on HMM: 89-169/325.0
HQKRYIATQGCLKDTVPEFWRVA--WQenSRVIVMTtKEVERGKNKCCRYWPDA-NTKKDTGVITVTHISEQSMADYDLREFSM
 .. ..|.|  | .|. ..||..  |.  . |.|..  |.. ||..|. |||.     |  | . |  .. . ..||  | . .
kkdvflaaqaPltatindlWrlvldWr..csvvvvl.neldlgkdrcavywpkemgksktfGglevklrtieeisdyvhrvldv

subfamily_Anemone-PTP-3_pd Subfamily Anemone-PTP-3 259-334 6.1e-09 30.3 In-house 3-79 (199) alignment
Range on Protein: 259-334
Range on HMM: 3-79/199.0
HQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRYWPDANTK-KDTGVITVTHISEQSMADYDL
 |.||||||  |..|. .||.. |.  |  |||   .    .     ||| ...     | ..||  .  . .|| .
gqrryiatqhplretmadfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdyti

subfamily_Sponge-PTP6_pd Subfamily Sponge-PTP6 259-340 6.1e-09 29.8 In-house 89-164 (439) alignment
Range on Protein: 259-340
Range on HMM: 89-164/439.0
HQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKnkccrYWPDANtKKDTGVITVTHISEQSMADYDLREFSMS
 .| ||||||  |.|. .|||. .....  ||| |. ||  |     |||  . .   | |.|    .  . .| .| | . 
ddklyiatqgpkkettddfwrlviekktvtivmltnlvesyk.....ywpsda.evcygdiavrvdrnielpnyvirgfkvf

subfamily_Anemone-PTP-1_pd Subfamily Anemone-PTP-1 260-341 1.1e-18 62.3 In-house 51-130 (239) alignment
Range on Protein: 260-341
Range on HMM: 51-130/239.0
QKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRYWPDANTKKDTgvITVTHISEQSMADYDLREFSMSH
 | |||||||.. .  .|||. |||   |||| |  .|  |.|| .||||. .|     . ||    . .||| .| | ||.
pkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdstskycn..lrvtlrktevfadyiirtfvmsq

subfamily_Nvec-PTP-1_pd Subfamily Nvec-PTP-1 260-341 1.1e-18 62.3 In-house 50-129 (239) alignment
Range on Protein: 260-341
Range on HMM: 50-129/239.0
QKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRYWPDANTKKDTgvITVTHISEQSMADYDLREFSMSH
 | |||||||.. .  .|||. |||   |||| |  .|  |.|| .||||. .|     . ||    . .||| .| | ||.
pkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdstskycn..lrvtlrktevfadyiirtfvmsq

subfamily_Cele-PTP-10_pd Subfamily Cele-PTP-10 260-322 3e-14 47.4 In-house 95-159 (305) alignment
Range on Protein: 260-322
Range on HMM: 95-159/305.0
QKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRYWPDANTKKDT--GVITVT
.||.|..|| | .|. ||| .  |..   |||  | || || ||..||| |. .| .  . | | 
ekrficaqgpldqtidefwwmviqnkveqivmlcktvelgklkcaqywpaaqgeklelksgivve

subfamily_CG42327_pd Subfamily CG42327 260-317 1.3e-13 45.3 In-house 71-128 (319) alignment
Range on Protein: 260-317
Range on HMM: 71-128/319.0
QKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRYWPDANTKKDTG
.  |||.|  |.|.  .|||. |. .|||||  |.  | | ..| .|.|  .| ..| 
pnsyiaaqvsledsssdfwrtvweqqsrvivqltdlselGikvcaeylPtketldnts

subfamily_Cele-PTP-13_pd Subfamily Cele-PTP-13 260-309 2.7e-11 37.7 In-house 80-129 (281) alignment
Range on Protein: 260-309
Range on HMM: 80-129/281.0
QKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRYWPD
.. || |||  |.|  .|||. ||||.  |||  . .|  ..||. |.| 
krgyiltqgpkketradfwrmiwqenttaivmlcqfletnrekcaeyfpr

subfamily_Cele-PTP-6_pd Subfamily Cele-PTP-6 260-321 3.1e-11 37.9 In-house 81-142 (307) alignment
Range on Protein: 260-321
Range on HMM: 81-142/307.0
QKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRYWPDANTKKDTGVITV
 |..|..|| |..|. .|| .| ||.   ..|  | .| .| || .|||  . .| . . . 
pkkficaqgplentqysfwamaiqekvesvimlckvielakikceqywpleegqklvfgeap

0049260 (Phosphotyrosine protein) phosphatases II 260-353 9.9e-11 37.0 In-house 8-64 (152) alignment
Range on Protein: 260-353
Range on HMM: 8-64/152.0
QKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRYWpdantkkdtgvitvthiseqsmadydlrefsmshkdfNKCCRYWPD
....|||||..  |...|||  .. . ..||| |...|.|| || .|.                                     . .. .|||
pfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi.....................................qylhlpwpD

subfamily_Nvec-PTP-3_pd Subfamily Nvec-PTP-3 260-335 6.8e-09 30.2 In-house 3-79 (198) alignment
Range on Protein: 260-335
Range on HMM: 3-79/198.0
QKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRYWPDANTK-KDTGVITVTHISEQSMADYDLR
|.||||||  |..|. .||.. |.  |  |||   .    .     ||| ...     | ..||  .  . .|| . 
qrryiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytit

subfamily_Cele-PTP-18_pd Subfamily Cele-PTP-18 260-311 7.5e-09 29.7 In-house 87-138 (305) alignment
Range on Protein: 260-311
Range on HMM: 87-138/305.0
QKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRYWPDAN
 ||.| ||  |..|  .|| . .|..   | |  . .|.| .||. |..  .
pkrfictqaplektcadfwymclqdkveaifmlcnllekgakkcleyfaskd

subfamily_eak_pd Subfamily eak 260-339 4e-07 23.7 In-house 92-172 (332) alignment
Range on Protein: 260-339
Range on HMM: 92-172/332.0
QKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRYWPDAN-TKKDTGVITVTHISEQSMADYDLREFSM
 ..|| |    .| |. ||..  ...|  ||.  ..|| . .|  .|.||    . . |.. |.  .    . .. | . .
GrkyiltGiasedkvfafwqmvleqkspaivqlledvelkleksdkyfpdktreelkfGildverkefvkrniletrllel

subfamily_Cele-PTP-11_pd Subfamily Cele-PTP-11 260-309 3.8e-06 20.8 In-house 81-130 (312) alignment
Range on Protein: 260-309
Range on HMM: 81-130/312.0
QKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRYWPD
 .|...||| |..|.  ||..|    |  |.. .  || | .||..|  |
perfvctqgplentcthfwqlalslgstsiillcgfvedgsekcakyisd

subfamily_Cele-PTP-14_pd Subfamily Cele-PTP-14 261-328 4.1e-14 46.8 In-house 94-161 (310) alignment
Range on Protein: 261-328
Range on HMM: 94-161/310.0
KRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRYWPDANTKKDTGVITVTHISEQS
. .| .|| |. |. .|||. .|| .  |..  | .| |. ||  |||     .  |.| || .|| |
stficsqgplqhtiidfwrmifqeraesilllckvgeegrpkcvgywpslgvtetygcirvtnlsess

subfamily_Cele-PTP-20_pd Subfamily Cele-PTP-20 261-342 6.5e-13 43.0 In-house 94-177 (290) alignment
Range on Protein: 261-342
Range on HMM: 94-177/290.0
KRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRYWPDANTKKDT-GVITVTHISEQ-SMADYDLREFSMSHK
  .| ||| ||||| ..||.  ||.  .|||  . .| || || .|.|. . .  | | |||.   |.   |.  .. .|. .|
amfiltqGalkdtvidiwrmvlqekvaaivmlceliedGkakceqyypekeGevltfGeitvlcseeddkdaniikktlsvrdk

0051082 (Phosphotyrosine protein) phosphatases II 261-346 2.2e-08 29.3 In-house 14-85 (151) alignment
Range on Protein: 261-346
Range on HMM: 14-85/151.0
KrYIATQGClkdtVPEFWRVAWQENSRVIVMTTKEVERGknKCCRYWPDANtkkdtgvITVTHISEQSMADYDLREFSMSHKDFNK
  .....|      ..|..  .... ..||. ..|.|||  .| .|.|...       |.|.||   .. |..| ..  . ..| .
g.lyrsggp....ladflellkelgiktivnlrseeerg..ycpeylpelg.......ievlhipildwpdpglplsfdavlefle

subfamily_egg_pd Subfamily egg 262-323 1.5e-12 41.8 In-house 84-143 (307) alignment
Range on Protein: 262-323
Range on HMM: 84-143/307.0
RYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERgkNKCCRYWPDANTKKDTGVITVTH
 .| .|  ||.|| .|||. .||. . ||| |  .|   ..|  ||| |...    |    .
efilaqaplkntvddfwrmvfqeevqyivmltsrkes..erceyywpkaesdslvtvpGslr

subfamily_PTPN23_pd Subfamily PTPN23 263-344 3.1e-16 54.0 In-house 85-167 (288) alignment
Range on Protein: 263-344
Range on HMM: 85-167/288.0
YIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRYWPDANTK-KDTGVITVTHISEQSMADYDLREFSMSHKDF
.||||. |. |. .||.. ... |.|||| ... |.||.|. |||| .. . .  | ..||  |....  .  |.......| 
fiatqaPlqstlnDFWlmvyeqkssviVmllskeelgkpkvdrYwPedkgetvkfgdlsvtlksvretethvervlkletlda

subfamily_Urchin-PTPRB-like_pd Subfamily Urchin-PTPRB-like 341-384 1.5e-06 22.5 In-house 126-169 (288) alignment
Range on Protein: 341-384
Range on HMM: 126-169/288.0
HKDFNKCCRYWPDANTKKDTGVITVTHISEQSMADYDLREFSMS
 .. .|| .|||||...|  | .||| .... . |. ||.. . 
eggktkCeeYWPdadkpknyGsvtvtlveskeledfvlrkllle

subfamily_Urchin-PTP-7_pd Subfamily Urchin-PTP-7 341-387 6.3e-06 20.3 In-house 128-172 (315) alignment
Range on Protein: 341-387
Range on HMM: 128-172/315.0
HKDFNKCCRYWPDAntKKDTGVITVTHISEQSMADYDLREFSMSHKD
... .|. .||||   |   | ||||..||.   .|  | .|.  .|
egekrkaekywpdk..kviyGkitvtrkseevnteytvrtlsvvfgd

0050432 (Phosphotyrosine protein) phosphatases II 342-385 4.3e-07 25.0 In-house 145-190 (308) alignment
Range on Protein: 342-385
Range on HMM: 145-190/308.0
KDFNKCCRYWPDA--NTKKDTGVITVTHISEQSMADYDLREFSMSH
.. .||..|||.   .. .  | .|||..||....|| .|.. ...
ngrekcaqYwplelgggsleygkftvtllseevlddytvrtleltn

0046845 (Phosphotyrosine protein) phosphatases II 342-387 5.8e-07 24.6 In-house 114-159 (284) alignment
Range on Protein: 342-387
Range on HMM: 114-159/284.0
KDFNKCCRYWPDANTKKDTGVITVTHISEQSMADYDLREFSMSHKD
.. .||..|||. ....  | .||| .||. . || .|........
ngrekcaqYwplegevltygdftvtllseevkddytvrtleltnlg

0042113 (Phosphotyrosine protein) phosphatases II 342-385 3.5e-06 22.1 In-house 89-131 (245) alignment
Range on Protein: 342-385
Range on HMM: 89-131/245.0
KDFNKCCRYWPDaNTKKDTGVITVTHISEQSMADYDLREFSMSH
....||..|||. .... .| .||| .||....|| .|......
lgrvkcaqywpl.gesltygdftvtllseehlddytvrtlevtn

0040439 (Phosphotyrosine protein) phosphatases II 342-386 5.3e-06 21.7 In-house 91-134 (249) alignment
Range on Protein: 342-386
Range on HMM: 91-134/249.0
KDFNKCCRYWPDaNTKKDTGVITVTHISEQSMADYDLREFSMSHK
....||..|||. .. .  | .||| .|.....|| .|.. ....
lgrekcaqywpl.ggsleygdftvtllsvevkddytvrtleltnl

0045098 (Phosphotyrosine protein) phosphatases II 342-386 7.2e-06 21.1 In-house 101-144 (278) alignment
Range on Protein: 342-386
Range on HMM: 101-144/278.0
KDFNKCCRYWPDaNTKKDTGVITVTHISEQSMADYDLREFSMSHK
.. .||..|||. .  .  | .||| .||. . || || . . . 
lgrekcaqywpe.ggsltygdftvtllseevlddytlrtllvtnl

subfamily_Sponge-PTP11_pd Subfamily Sponge-PTP11 342-386 9.5e-06 19.7 In-house 128-171 (290) alignment
Range on Protein: 342-386
Range on HMM: 128-171/290.0
KDFNKCCRYWPDANTKKdTGVITVTHISEQSMADYDLREFSMSHK
.. .||  ||||..||.  | .... ..|... .|  |.... .|
egkvkCqqYWpdsdtka.ygefsikllneetlneyierklevknk

0051299 (Phosphotyrosine protein) phosphatases II 343-386 3.2e-07 25.6 In-house 130-172 (288) alignment
Range on Protein: 343-386
Range on HMM: 130-172/288.0
DFNKCCRYWPDaNTKKDTGVITVTHISEQSMADYDLREFSMSHK
. .||..|||. ....  | |||| .||....|| .|.. ....
grekcaqYwpl.ggsltygditvtllseevlddytvrtlevtnl

0047943 (Phosphotyrosine protein) phosphatases II 343-385 6.4e-06 21.3 In-house 115-159 (273) alignment
Range on Protein: 343-385
Range on HMM: 115-159/273.0
DFNKCCRYWPDANT--KKDTGVITVTHISEQSMADYDLREFSMSH
. .||..|||. .   ..  | .|||..||.. .|| .|.. ...
grekcaqYwpleggelsltygkftvtllseetkddytvrtleltn

0045450 (Phosphotyrosine protein) phosphatases II 343-386 8.6e-06 21.2 In-house 145-188 (307) alignment
Range on Protein: 343-386
Range on HMM: 145-188/307.0
DFNKCCRYWPDANTKKDTGVITVTHISEQSMADYDLREFSMSHK
...||..|||| ....  | .||| .||. ...| .| . ....
grekcaqywPdegeeltygnftvtllseehldgytvrtlevtdl

subfamily_PTPRD_pd Subfamily PTPRD 344-386 3.7e-07 24.2 In-house 130-171 (564) alignment
Range on Protein: 344-386
Range on HMM: 130-171/564.0
FNKCCRYWPDANtKKDTGVITVTHISEQSMADYDLREFSMSHK
 .|| .|||. . ..  | .|||  .|. .||| .|.|....|
kvkchkYWPekg.tetygeltVtleeeeeladyeirtfklkkk

0040438 (Phosphotyrosine protein) phosphatases II 344-386 1.1e-06 23.6 In-house 125-166 (317) alignment
Range on Protein: 344-386
Range on HMM: 125-166/317.0
FNKCCRYWPDaNTKKDTGVITVTHISEQSMADYDLREFSMSHK
 .||..|||. ....  | .|||..||. .|.. ||.. ....
rekcaqYwpl.getltygdftvtllseeelagitlrtlevedl

subfamily_PTPN6_pd Subfamily PTPN6 345-387 2.7e-16 54.4 In-house 138-180 (306) alignment
Range on Protein: 345-387
Range on HMM: 138-180/306.0
NKCCRYWPDANTKKDTGVITVTHISEQSMADYDLREFSMSHKD
.||.|||||...|...|.|.||..||.|.|||.|||.|.|.|.
ekCarYWPdeeekeeyGkisvtnvseksladYilRelsvskkk

subfamily_PTPRB_pd Subfamily PTPRB 345-386 1.4e-06 22.5 In-house 134-175 (293) alignment
Range on Protein: 345-386
Range on HMM: 134-175/293.0
NKCCRYWPDANTKKDTGVITVTHISEQSMADYDLREFSMSHK
 || .|||. ..    | |.|| ..|... |. .||......
vkCeeYWPadeepvlyGdikvtlvaeeeledwvirelkieke

subfamily_Ptp69D_pd Subfamily Ptp69D 345-387 1.5e-06 22.5 In-house 131-172 (307) alignment
Range on Protein: 345-387
Range on HMM: 131-172/307.0
NKCCRYWPDAnTKKDTGVITVTHISEQSMADYDLREFSMSHKD
.|| .|||.  ...  | | |. .||... ||  ||...|.|.
kkcakYWpie.devqygdilvklvseekhsdyiiReldvskkk

subfamily_Anemone-PTP-4_pd Subfamily Anemone-PTP-4 345-385 2.9e-06 21.7 In-house 85-125 (237) alignment
Range on Protein: 345-385
Range on HMM: 85-125/237.0
NKCCRYWPDANTKKDTGVITVTHISEQSMADYDLREFSMSH
 || .|||...  .  ||.||.   .. ..|| .| . .|.
lkchkywpstdqpaaygvltvslkkkeefsdytvrslllsk