Gene SpurPTP-sf1-7 in Strongylocentrotus purpuratus

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family PTP
Subfamily SpurPTP-sf1
Protein sequence
ID Type Fasta BLAST phosphatome Note
SpurP084_AA protein Get Run
SpurP084_AA_1-61 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_Urchin-PTP-6_pd Subfamily Urchin-PTP-6 1-21 1.8e-07 24.7 In-house 347-367 (515) alignment 
Range on Protein: 1-21
Range on HMM: 347-367/515.0
QRNRVILDSPDQDYINASQMK
|||||||||||.|||||||||
qrnrvildspdhdyinasqmk
subfamily_Urchin-PTP-1_pd Subfamily Urchin-PTP-1 1-22 2.2e-06 21.8 In-house 57-82 (315) alignment 
Range on Protein: 1-22
Range on HMM: 57-82/315.0
QRNRVIL----DSPDQDYINASQMKS
...||.|    ||||.||||||..||
dsarvkleviddsPdsdyinasyiks
0050432 (Phosphotyrosine protein) phosphatases II 2-60 2.7e-14 48.7 In-house 82-190 (308) alignment 
Range on Protein: 2-60
Range on HMM: 82-190/308.0
RNRVILdSPDQDYINASQMKSC------------------------------------------------AQYWPDA---DSAQFGSYSVATLSTSSDGD
..||.| ... |||||| .. .                                                |||||.    .| ..| ..| .||. ...|
hsRVkl.degsdYInAsyvdgyssklprkfIatqgPlpntvedFwrmvweqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseevldd

VTTRQMKVTR
.|.|....| 
ytvrtleltn
0047943 (Phosphotyrosine protein) phosphatases II 2-60 1e-13 46.8 In-house 52-159 (273) alignment 
Range on Protein: 2-60
Range on HMM: 52-159/273.0
RNRVILDSPDQDYINASQMKS----------------------------------------------CAQYWPDAD---SAQFGSYSVATLSTSSDGDVT
..||.|.... |||||| ..                                               ||||||.     | ..| ..| .||. ...|.|
hsrvklgdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvweqnvrviVmLtelvelgrekcaqYwpleggelsltygkftvtllseetkddyt

TRQMKVTR
.|....|.
vrtleltn
0051299 (Phosphotyrosine protein) phosphatases II 2-61 1.2e-13 46.7 In-house 63-172 (288) alignment 
Range on Protein: 2-61
Range on HMM: 63-172/288.0
RNRVILDS----PDQDYINASQMKS----------------------------------------------CAQYWPDADSAQFGSYSVATLSTSSDGDV
..||.| .    .. |||||| ..                                               ||||||. .| ..| ..| .||. ...|.
hsRVkLsvldgvegsdYinAsyidgynlkrkfIatqgPlpntvedFWrmvweqnvrvIvmltklvelgrekcaqYwplggsltygditvtllseevlddy

TTRQMKVTRN
|.|...||..
tvrtlevtnl
0036941 (Phosphotyrosine protein) phosphatases II 2-60 1.4e-12 43.0 In-house 53-161 (297) alignment 
Range on Protein: 2-60
Range on HMM: 53-161/297.0
RNRVILDSPDQDYINASQMKS----------------------------------------------CAQYWPDA--DSAQFGSYSVATLSTSS--DGDV
..||.||... |||||| ..                                               ||||||.   .| ..| ..| .||...  ..|.
htRVklddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqnvtvIvmltelvelgrekcaqywpleegesltygdftvtllsvevvllddy

TTRQMKVTR
|.|...|| 
tlrtlevtd
0046845 (Phosphotyrosine protein) phosphatases II 2-61 2.7e-12 42.1 In-house 42-158 (284) alignment 
Range on Protein: 2-61
Range on HMM: 42-158/284.0
RNRVILDS-----PDQDYINASQMKS---------------------------------------------------CAQYWPDAD-SAQFGSYSVATLS
..||.|.|     .| |||||| ..                                                    ||||||. . . ..| ..| .||
hsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqnvrvIVmltelvengrekcaqYwplegevltygdftvtlls

TSSDGDVTTRQMKVTRN
.  ..|.|.| ...|..
eevkddytvrtleltnl
0040438 (Phosphotyrosine protein) phosphatases II 2-61 3.2e-12 41.8 In-house 57-166 (317) alignment 
Range on Protein: 2-61
Range on HMM: 57-166/317.0
RNRVILDSPD----QDYINASQMKS----------------------------------------------CAQYWPDADSAQFGSYSVATLSTSSDGDV
..||.| ...     |||||| ..                                               ||||||. .. ..| ..| .||.  ....
hsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPlpntvedFwrmvweqgvtvivmLteleelgrekcaqYwplgetltygdftvtllseeelagi

TTRQMKVTRN
| |...|. .
tlrtlevedl
0045450 (Phosphotyrosine protein) phosphatases II 2-61 3.1e-11 39.0 In-house 69-188 (307) alignment 
Range on Protein: 2-61
Range on HMM: 69-188/307.0
RNRVILDS-----PDQDYINASQM------------------------------------------------------KSCAQYWPDADSA-QFGSYSVA
..||.| |     .| |||||| .                                                      . ||||||| ..  ..| . | 
htRVklssldgsledsdYiNAsyvrvpllllldgydlkrkfIatqgPlpetvedFwrmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvt

TLSTSSDGDVTTRQMKVTRN
.||.. ....| |...||..
llseehldgytvrtlevtdl
0043336 (Phosphotyrosine protein) phosphatases II 2-61 8e-11 37.4 In-house 59-167 (278) alignment 
Range on Protein: 2-61
Range on HMM: 59-167/278.0
RNRVILDSPD----QDYINASQM----------------------------------------------KSCAQYWPdADSAQFGSYSVATLSTSSDGDV
..||.|.. .     |||||| .                                              . ||||||  .| ..| ..| .|.. ...|.
hsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpetvedFwrmvwelgvttivmLtelvelgrvkcaqYwp.ggsltygdftvtllkeehlddy

TTRQMKVTRN
|.|...||..
tvrtlevtnl
0039614 (Phosphotyrosine protein) phosphatases II 2-61 9.2e-11 37.2 In-house 70-179 (297) alignment 
Range on Protein: 2-61
Range on HMM: 70-179/297.0
RNRVILDS-----PDQDYINASQMKS----------------------------------------------CAQYWPDADSaQFGSYSVATLSTSSDGD
..||.| .     .| |||||| ..                                               ||||||.  . ..| ..| .|..  ...
hsrvklkpedgvdldsdYinAsyvdgydlltrkfIatqgPlpetvedFwrmvweqgvtvivmLtklvelgrkcaqywpeegg.tygdftvtllkvehldg

VTTRQMKVTRN
.|.|...||.|
ytvrtlevtnn
0042113 (Phosphotyrosine protein) phosphatases II 2-60 1.3e-10 36.6 In-house 23-131 (245) alignment 
Range on Protein: 2-60
Range on HMM: 23-131/245.0
RNRVILDSPD----QDYINASQM----------------------------------------------KSCAQYWPDADSAQFGSYSVATLSTSSDGDV
..||.| ...     |||||| .                                              . ||||||. .| ..| ..| .||. ...|.
htrvklspdggdldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywplgesltygdftvtllseehlddy

TTRQMKVTR
|.|...||.
tvrtlevtn
0040439 (Phosphotyrosine protein) phosphatases II 2-60 3.6e-10 35.4 In-house 25-133 (249) alignment 
Range on Protein: 2-60
Range on HMM: 25-133/249.0
RNRVILDS----PDQDYINASQMKS----------------------------------------------CAQYWPDADSAQFGSYSVATLSTSSDGDV
..||.| .    .. |||||| ..                                               ||||||. .| ..| ..| .||. . .|.
hsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywplggsleygdftvtllsvevkddy

TTRQMKVTR
|.|....|.
tvrtleltn
0045098 (Phosphotyrosine protein) phosphatases II 2-60 2.3e-09 32.6 In-house 47-143 (278) alignment 
Range on Protein: 2-60
Range on HMM: 47-143/278.0
RNRVIldspdqDYINASQMK--------------------------------------------SCAQYWPDADSAQFGSYSVATLSTSSDGDVTTRQMK
..||.      |||||| ..                                             ||||||. .| ..| ..| .||..  .|.|.| ..
hsrVk......dYINAsyidgypkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaqywpeggsltygdftvtllseevlddytlrtll

VTR
|| 
vtn
0037934 (Phosphotyrosine protein) phosphatases II 2-60 1.3e-08 30.2 In-house 24-125 (243) alignment 
Range on Protein: 2-60
Range on HMM: 24-125/243.0
RNRVILdsPDQDYINAS-----------------------------------------------QMKSCAQYWPdaDSAQFGSYSVATLSTSSDGDVTTR
..||.|  .. |||||.                                               ... ||||||  .. ..| ..| .||... .|.| |
hsrvkl..egsdyinanliyvtprliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywp..gevtygdftvtllseehlddytvr

QMKVTR
 .....
tlllen
subfamily_Sponge-PTP11_pd Subfamily Sponge-PTP11 16-62 3.6e-09 30.9 In-house 126-172 (290) alignment 
Range on Protein: 16-62
Range on HMM: 126-172/290.0
NASQMKSCAQYWPDADSAQFGSYSVATLSTSSDGDVTTRQMKVTRNS
. .. . | |||||.|....| .|.  |. ..  . ..|...|. ..
ieegkvkCqqYWpdsdtkaygefsikllneetlneyierklevknkn
subfamily_CG7180_pd Subfamily CG7180 17-61 4.9e-06 20.4 In-house 120-164 (296) alignment 
Range on Protein: 17-61
Range on HMM: 120-164/296.0
ASQMKSCAQYWPDADSAQFGSYSVATLSTSSDGDVTTRQMKVTRN
 ...| . .|||    .|.|   | .... .  ....|..|.|..
fdfakmypsywpnkskeqygeifveiveekqyanlkirtfkltkk
subfamily_Urchin-PTP-3_pd Subfamily Urchin-PTP-3 18-60 2.2e-06 22.1 In-house 127-171 (325) alignment 
Range on Protein: 18-60
Range on HMM: 127-171/325.0
SQMKSCAQYWPDA--DSAQFGSYSVATLSTSSDGDVTTRQMKVTR
 . ..||.|||.   .| .||.  |   .     |   |...| .
lgkdrcavywpkemgksktfGglevklrtieeisdyvhrvldvkq
subfamily_Ptp69D_pd Subfamily Ptp69D 19-62 1e-07 26.4 In-house 129-172 (307) alignment 
Range on Protein: 19-62
Range on HMM: 129-172/307.0
QMKSCAQYWPDADSAQFGSYSVATLSTSSDGDVTTRQMKVTRNS
. | ||.|||. |  |.|.  | . |... .| . |...|... 
nrkkcakYWpiedevqygdilvklvseekhsdyiiReldvskkk
subfamily_Sponge-PTP8_pd Subfamily Sponge-PTP8 19-61 9.7e-07 23.2 In-house 127-171 (305) alignment 
Range on Protein: 19-61
Range on HMM: 127-171/305.0
QMKSCAQYWPDADSA--QFGSYSVATLSTSSDGDVTTRQMKVTRN
. . | ||||.. .   .||..||   |...  | ..|..|.. .
gkdkCrqYWpesktekkefgefsvelksektasdyieRklkisie
subfamily_Urchin-PTP-5_pd Subfamily Urchin-PTP-5 20-62 1.8e-09 32.2 In-house 130-172 (297) alignment 
Range on Protein: 20-62
Range on HMM: 130-172/297.0
MKSCAQYWPDADSAQFGSYSVATLSTSSDGDVTTRQMKVTRNS
 |.||.||.|  ...||. || .||.|.      |...||...
dkkcaryWsdkgvttfGdvsvvllsvsereGfikrelevtkgk
subfamily_Nvec-PTP-2_pd Subfamily Nvec-PTP-2 20-62 3e-08 28.2 In-house 90-132 (250) alignment 
Range on Protein: 20-62
Range on HMM: 90-132/250.0
MKSCAQYWPDADSAQFGSYSVATLSTSSDGDVTTRQMKVTRNS
 | . ||||   . ..|.  |  ||.   .|.|.|..|.....
ektyhqywPvekaekyGdvtvsllskeefadytkrklklskak
subfamily_Sponge-PTP10_pd Subfamily Sponge-PTP10 20-61 5.7e-07 23.8 In-house 125-166 (287) alignment 
Range on Protein: 20-61
Range on HMM: 125-166/287.0
MKSCAQYWPDADSAQFGSYSVATLSTSSDGDVTTRQMKVTRN
 . | ||||. .|  .| |... |.     ... |...|...
eevcyqyWpeeksvvlGeyniellneevnagyierklevknk
subfamily_PTPRK_pd Subfamily PTPRK 20-60 2.2e-06 21.7 In-house 125-164 (314) alignment 
Range on Protein: 20-60
Range on HMM: 125-164/314.0
MKSCAQYWPDADSAqFGSYSVATLSTSSDGDVTTRQMKVTR
   | .|||.  .  .|   |  ..|. . .. .| ..|..
rvkClkyWPedtev.ygdikvelvetellaelvvrifrvek
DSPc_SM00195 20-61 6.8e-06 21.0 In-house 108-152 (263) alignment 
Range on Protein: 20-61
Range on HMM: 108-152/263.0
MKSCAQYWPDA--DSAQFGSYSVATLSTSSDG-DVTTRQMKVTRN
 . |..|||.   .. .||..|| . .. ..  ....|....| .
kekcdrywpeesggketfgkisvklvevekkkdeiilrtleltke
PTPc_SM00194 20-61 6.8e-06 21.0 In-house 108-152 (263) alignment 
Range on Protein: 20-61
Range on HMM: 108-152/263.0
MKSCAQYWPDA--DSAQFGSYSVATLSTSSDG-DVTTRQMKVTRN
 . |..|||.   .. .||..|| . .. ..  ....|....| .
kekcdrywpeesggketfgkisvklvevekkkdeiilrtleltke
subfamily_Urchin-PTP-6_pd Subfamily Urchin-PTP-6 21-62 9.9e-19 61.8 In-house 410-451 (515) alignment 
Range on Protein: 21-62
Range on HMM: 410-451/515.0
KSCAQYWPDADSAQFGSYSVATLSTSSDGDVTTRQMKVTRNS
||||||||||.| |||||||.|||||||||.| ||..|||||
kscaqywpdansvqfgsysvstlstssdgdmtirqlqvtrns
subfamily_Urchin-PTPRB-like_pd Subfamily Urchin-PTPRB-like 21-62 2.8e-07 24.9 In-house 130-172 (288) alignment 
Range on Protein: 21-62
Range on HMM: 130-172/288.0
KSCAQYWPDADS-AQFGSYSVATLSTSSDGDVTTRQMKVTRNS
. | .||||||   ..||  |  ...   .|...|.. . .. 
tkCeeYWPdadkpknyGsvtvtlveskeledfvlrklllekkk
subfamily_PTPN9_pd Subfamily PTPN9 21-60 9.9e-07 23.1 In-house 125-166 (297) alignment 
Range on Protein: 21-60
Range on HMM: 125-166/297.0
KSCAQYWP--DADSAQFGSYSVATLSTSSDGDVTTRQMKVTR
  |.||||  . .||.||..||..... .  | ..|......
lkcgqyWpleeessaefgdlsvsnveveeeedykvrvleikn
subfamily_PTPRD_pd Subfamily PTPRD 21-61 1.6e-06 22.1 In-house 131-171 (564) alignment 
Range on Protein: 21-61
Range on HMM: 131-171/564.0
KSCAQYWPDADSAQFGSYSVATLSTSSDGDVTTRQMKVTRN
. |..|||. .....|.. |   ..    |.. |..|....
vkchkYWPekgtetygeltVtleeeeeladyeirtfklkkk
subfamily_Anemone-PTP-6_pd Subfamily Anemone-PTP-6 21-61 2e-06 22.1 In-house 129-169 (318) alignment 
Range on Protein: 21-61
Range on HMM: 129-169/318.0
KSCAQYWPDADSAQFGSYSVATLSTSSDGDVTTRQMKVTRN
. ...|||. .| ..|.  |   .. . .| . |..||||.
akvhryWPskgsrsygklvvelkeevelsdyvlrefkvtrt
Y_phosphatase Protein-tyrosine phosphatase 21-61 7.6e-06 20.9 Pfam-A 82-126 (235) alignment 
Range on Protein: 21-61
Range on HMM: 82-126/235.0
KSCAQYWP--DADSAQFGSYSVATL-STS-SDGDVTTRQMKVTRN
. ||||||  . .| ..|...| .  ...  . ..|.|..... .
ekcaqYwpeeeeesltygdikvelkekekedekeytlrklelkkk
Y_phosphatase Protein-tyrosine phosphatase 21-61 7.6e-06 20.9 In-house 82-126 (235) alignment 
Range on Protein: 21-61
Range on HMM: 82-126/235.0
KSCAQYWP--DADSAQFGSYSVATL-STS-SDGDVTTRQMKVTRN
. ||||||  . .| ..|...| .  ...  . ..|.|..... .
ekcaqYwpeeeeesltygdikvelkekekedekeytlrklelkkk
NTP_transf_2 Nucleotidyltransferase domain 21-51 8.9e-06 12.5 Pfam-A 6-36 (93) alignment 
Range on Protein: 21-51
Range on HMM: 6-36/93.0
KSCAQYWPDADSAQFGSYSVATLSTSSDGDV
... .....|. . ||||   ||   || |.
erlkelygvaevvlfGSyarGtllpgSDiDl
subfamily_Urchin-PTP-1_pd Subfamily Urchin-PTP-1 22-63 3.9e-16 53.8 In-house 128-170 (315) alignment 
Range on Protein: 22-63
Range on HMM: 128-170/315.0
SCAQYWPD--ADSAQFGSYSVATLSTSSDGDVTTRQMkVTRNSN
.|.|||||  |||..|||..|..||...|.| ..|.. |||.|.
kcrqywPdrkadsvefGsikvellsleadtdgvarkl.vtrkse
subfamily_Anemone-PTP-2_pd Subfamily Anemone-PTP-2 22-62 2.5e-07 25.2 In-house 140-180 (298) alignment 
Range on Protein: 22-62
Range on HMM: 140-180/298.0
SCAQYWPDADSAQFGSYSVATLSTSSDGDVTTRQMKVTRNS
 . .||||  ....|. .|  ||. . .|...|..||....
kyhkywPdegketygeitvsllskeefadlivrklkvskkk
subfamily_PTPN3_pd Subfamily PTPN3 22-61 1.8e-06 22.1 In-house 125-165 (280) alignment 
Range on Protein: 22-61
Range on HMM: 125-165/280.0
SCAQYWPDA-DSAQFGSYSVATLSTSSDGDVTTRQMKVTRN
 | ||||.  |. ..|..||   .....  . .|.. ....
kChqyWPetedeleygefsvkcekedetksyvlrelvlkdk
subfamily_Urchin-PTP-4_pd Subfamily Urchin-PTP-4 39-62 9.1e-06 19.3 In-house 251-274 (392) alignment 
Range on Protein: 39-62
Range on HMM: 251-274/392.0
SVATLSTSSDGDVTTRQMKVTRNS
 ...|||||||||...|.|..|..
hlqdlstssdGdvrskqlkefrsl