Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
fn3 | Fibronectin type III domain | 322-398 | 9.1e-10 | 31.7 | Pfam-A | 8-82 (85) | alignment | ||
Range on Protein: 322-398
Range on HMM: 8-82/85.0
IVSTTSTTVGLRWDAWSeeddIGDPPLVGYDVFVM-E-DGD-WVMDQRANQLTtSAIVSNLTPDTDYRFGVAAVREGTGG
. ..|||.. |.|.. . |. |..||.| . . .|. |. .. .. | |.....|.|.|.|.| |.|| ....|
vsevtstsltlsWsppk....dgggpitgYeveyrekgggeewkeftvprttt.svtltgLkpgteYefrVqavngageg
|
|||||||||
fn3 | Fibronectin type III domain | 418-504 | 1.5e-13 | 43.8 | Pfam-A | 2-85 (85) | alignment | ||
Range on Protein: 418-504
Range on HMM: 2-85/85.0
SPTGLQVSAINHKELEVTWEHLPsksaECRSGVTNYMIYYAPTGSTS-SNSILVRNDTSSYTLGGLDTYLNYTIQLTASNKDEESDRS
.|..|.||.... .|...|.. . . .. .|.| . |...|... .... | ..|.|.|| || . .|.....| |.. |. .|
aPenlsvsevtstsltlsWsppk....dgggpitgYeveyrekgggeewkeftvprtttsvtltgLkpgteYefrVqavngagegpeS
|
|||||||||
subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 571-862 | 2.3e-122 | 402.8 | In-house | 6-297 (297) | alignment | ||
Range on Protein: 571-862
Range on HMM: 6-297/297.0
TRQPLPLAQFPTFVNKNRHTTLFSEEFHDLPGPNIYPQTVAQEEINFKKNRYKNILPYDSVRVKLEVINDNPHSDYFNASYIPSFDNdkAYIASQGPNKA
|.|.||..|.|.|.|||||..|||||..|| ||.|||||.. .||.|.|||||||||| ||||...||.| |||.|||..... . .|..| |.||
errpiplsdfatlvqknrhtdvfseeflclpeaniqpqtvaekkvnfeksRYkniLPydssRvkLaivnddpdsDyvnasfvkgnkh..rlittqmPmka
SMDDFWRMVWQENVTTIAMVTKLKEGDKiKCGKYWPNKPgdSVKFGYIRVELVSLEACTGGIKRTMTMLKGD--DCRTVTQFHFTEWPDKGVPK--HTSA
...|||.||..|.|.||.|.....|.|| || .||..| ...||.. |.| |.. ..|.|||.... ||. | | |..|.||||| |.. ..|.
tvadfWamvldeqvstivmlnddnerdk.kcaryWsdkg..vttfGdvsvvllsvsereGfikrelevtkgkakarrvvkqyqfveWPdkaverkdsass
LLKFIKEVKADHGQYTH-PLIIHCSAGVGRTGVVISIDSVVAHAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLEDLLWRNTLIPVIHFT
|||.|.||. |..| .. ||..||.||||||||...||||||.|| . ||.|..|. .||.|||.|||.|||.|.| |||| || .| |.. .|.
llklisevrkdfsqnaegPllvhclaGvGrtgvlltidsvvaeakrekevdifglvkklrqerpylvqtkeqykfvyvavleallsedtriqasyfe
|
|||||||||
subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 572-889 | 4e-171 | 563.7 | In-house | 1-276 (392) | alignment | ||
Range on Protein: 572-889
Range on HMM: 1-276/392.0
RQPLPLAQFPTFVNKNRHTTLFSEEFHDLPGPNIYPQTVAQEEINFKKNRYKNILPYDSVRVKLEVINDNPHSDYFNASYIPSFDNDKAYIASQGPNKAS
|||.| ||||.||.||||..||.|||||||||.||||||||.||| ||||||||||||| |||||||.| |.|||.||||||||||.|||||||||| ||
rqpipvaqfpafveknrhsalffeefhdlpgpdiypqtvaqkeinlkknryknilpydsarvkleviddipdsdylnasyipsfdnekayiasqgpnaas
MDDFWRMVWQENVTTIAMVTKLKEGDkikcgkywpnkpgdsvkfgyirvelvsleactggikrtmtmlKGDDCRTVTQFHFTEWPDKGVPKHTSALLKFI
.|||||||.||||||||||||||||| ||||.|||.||||||||||.||||||.|||||
lddfwrmvfqenvttiamvtklkegd..........................................kgddartvaqfhftewPdkdvpkhtssllkfi
KEVKADHGQYTHPLIIHCSAGVGRTGVVISIDSVVAHAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLEDLLWRNTLIPVIHFTDHLQDLHSS
||||||.||||||||||||||||||||||||||||||||.||||||||||||||.||||||||.|||||||||||||||||||||||.|||||||||..|
kevkadfGqythpliihcsagvgrtgvvisidsvvahakktrmvdvfnfvtnirrkrpymvqtkeqyafiygavledllwrntlipvvhftdhlqdlsts
GDGHGRSKMTKEFQTLKS
.||..|||..|||..||.
sdGdvrskqlkefrslka
|
|||||||||
subfamily_PTPRD_pd | Subfamily PTPRD | 572-927 | 2e-123 | 408.0 | In-house | 2-358 (564) | alignment | ||
Range on Protein: 572-927
Range on HMM: 2-358/564.0
RQPLPLAQFPTFVNKNR--HTTLFSEEFHDLPGPNIYPQTVAQEEINFKKNRYKNILPYDSVRVKLEVINDNPHSDYFNASYIPSFDNDKAYIASQGPNK
..|.| |.....|.| . . . |.||.... .. . ..|....| .||||.||..||. ||.|. .. .. ||| |||.| .....|||||.||| .
skpipvaelkehvaklkansdlkfeeeykkieegqqftweaankpaNkaKNRyanivaYdhsRVvLskvegdegsDYINAsfidgyrkrkayIAtqgPla
ASMDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKpGdSVKFGYIRVELVSLEACTGGIKRTMTMLK--GDDCRTVTQFHFTEWPDKGVPKHTSAL
...|||||||..|..|| |.|||.| .| || ||||.| | . ..|.. |.|.. | . . ||... | .. |.|.|||||.|||.|||... .|
etiedFWRmvweqnsstiVmltkleEkgkvkchkYWPek.g.tetygeltVtleeeeeladyeirtfklkkkkssesreVrqFhFtsWPdhgvpesatsl
LKFIKEVKADHGQYTHPLIIHCSAGVGRTGVVISIDSVVAHAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLEDLLWRNTLIPVIHFTDHLQD
|..|..|.| . . ..|...||||||||||. | ||... .|. ..||....|...|..|..||||.|||.||. |.|| | || ... ....|||
LdlirkvralnepdagPivVhCSaGVGRTGtfividamlerikeektvDiyqyvkalrkqRnamVqteeQYiFiheailealacgntevesenlkqhlqk
LHSSGDGHGRSKMTKEFQTLKSLCPDPpASQTRSGRTRDNHPKNRYGNNLPLQRNRVILD
|.. .... ... .||| |.. ... ... .. |. |||. | |.|...||.|.
LaeveedtemtgleleFqrLatakeie.leefavatkpknkkknrfsnilalescrvvls
|
|||||||||
subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 572-866 | 1.4e-88 | 291.9 | In-house | 3-296 (315) | alignment | ||
Range on Protein: 572-866
Range on HMM: 3-296/315.0
RQPLPLAQFPTFVNKNRHTT--LFSEEFHDLPGPNIYPQTVAQEEINFKKNRYKNILPYDSVRVKLEVINDNPHSDYFNASYIPSFDNDKAYIASQGPNK
.||.|| |. |.| ... .| | ... .|| ...| ||.. | .|||| ||..|| ||.| ... .||||| ||..|. .. . |||.||||
hqpipldqlityvaqkkastkngfkqdyesipggqlhpldvakkienkqknryiniiaydksrvqlpllendphsdyvnanfidGynkkrryiaaqgpnv
ASMDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKpgdSVKFGYIRVELVSLEACTGGIKRTMTMLKGDDCRTVTQFHFTEWPDKGVPKHTSALLK
||..||||.|..|....| |.|.| ||.| |. ||||.| | .| | | ..| | | ||... ||. |.| |.|.| ||| ||||.| .|..
asvkdfwrlvfeedigkivmltnlvegekrkaekywpdk...kviyGkitvtrkseevnteytvrtlsvvfgdnirevvqlhytswpdmgvpkytiplmn
FIKEVKADHGQYTHPLIIHCSAGVGRTGVVISIDSVVAHAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLEDLLWRNTLIPVIHFTDHLQ
.|. || | . ....|||||||||| |..|.|. .|.. ...||.||.|..||.| |||. ||| ||| |.|| .. .| | . .. .
lirtvkqhhtnsvgaivvhcsaGvGrtGtfitldavldqaeaenaidvynfitgvrqnrikmvqvaeqyqfiydalletfvcgdtsiaqdlylqryd
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 572-655 | 3.1e-13 | 43.8 | In-house | 3-86 (440) | alignment | ||
Range on Protein: 572-655
Range on HMM: 3-86/440.0
RQPLPLAQFPTFVNKNRHTTLFSEEFHDLPGPNIYPQTVAQEEINFKKNRYKNILPYDSVRVKLEVINDNPHSDYFNASYIPSF
..|. .|.| .|..|| . | .|. || | .| | ||||.||| || || || .. |.||| ||||| .
qrpiivadfadyvqnnrrsrafedewsllpsglsqpsdiaslpnnkvknryrnilaydhsrvmleevkgvpdsdyinasyingi
|
|||||||||
subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 573-887 | 5.6e-184 | 605.1 | In-house | 1-315 (315) | alignment | ||
Range on Protein: 573-887
Range on HMM: 1-315/315.0
QPLPLAQFPTFVNKNRHTTLFSEEFHDLPGPNIYPQTVAQEEINFKKNRYKNILPYDSVRVKLEVINDNPHSDYFNASYIPSFDNDKAYIASQGPNKASM
||.|.||||.||||||||.||||||||||.|.||.|.||.|.|||||||||||||.|| |||||||.|.|.|||.|||||.|.|.||||||||||.|||.
qpipvaqfpafvnknrhtalfseefhdlpdPdiyrqrvaretinfkknryknilPldsarvkleviddsPdsdyinasyiksvdddkayiasqgPlkasv
DDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPGDSVKFGYIRVELVSLEACTGGIKRTMTMLKGDDCRTVTQFHFTEWPDKGVPKHTSALLKFIK
|||||||.||.||||.||||..||||||| .|||.. .|||.|| |.|||.||||.|.|..| ... |... ||||||.|||||||||.|.||.|||.||
ddfwrmvlqekvttivmvtkkqegdkikcrqywPdrkadsvefGsikvellsleadtdgvarklvtrkseesrtvtqfqftewPdkGvdkqtssllklik
EVKADHGQYTHPLIIHCSAGVGRTGVVISIDSVVAHAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLEDLLWRNTLIPVIHFTDHLQDLHSSG
|||||.|.....|..||||||||||||||||.|||..| ||.|||||||.|.|.||||.|||.|.|||||.|||||||||||||.||||||||||||.|.
evkadngkkefsllvhcsaGvGrtGvvisidevvaqikrtrsvdvfnfvknlrakrpylvqteeeyafiydavledllwrntlilvihftdhlqdlhtsv
DGHGRSKMTKEFQTL
||.|||||||||.||
dgsgrskmtkefetl
|
|||||||||
0050432 | (Phosphotyrosine protein) phosphatases II | 573-853 | 2.1e-90 | 298.5 | In-house | 24-303 (308) | alignment | ||
Range on Protein: 573-853
Range on HMM: 24-303/308.0
QPLPLAQFPTFVNKNRHTTLFSEEFHDLPGPNIYPQ-TVAQEEINFKKNRYKNILPYDSVRVKLevindNPHSDYFNASYIPSF--DNDKAYIASQGPNK
.|.. .. ...| ..|..|||..|. .... .||. . |..|||||.|||||. |||| ...||| ||||.. . ......|| ||| .
lklsvldllkllekaldlglleeefeellsvkplleysvallpenkdkNrykdilpydhsRVkl.....degsdYInAsyvdgyssklprkfIatqgPlp
ASMDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPG-DSVKFGYIRVELVSLEACTGGIKRTMTMLK--GDDCRTVTQFHFTEWPDKGVPKHTSA
...|||||||..||..| |.||| | ...|| .|||...| .|...|...|.|.| | . . ..||... . ... ||||.||.| ||| ||| ....
ntvedFwrmvweqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseevlddytvrtleltnlgdgesrtvthfhytnWpdhgvPpspei
LLKFIKEVKADHGQytHPLIIHCSAGVGRTGVVISIDSVVAHAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLEDLLWRN
||.|...|. ... .| ..||||||||||..| .| .. . .....||||. | .|..||.|||| ||| |.| |.|| |...
lldflelvrkslpg..gpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylflyralleylklkl
|
|||||||||
subfamily_PTPRB_pd | Subfamily PTPRB | 573-847 | 1.2e-89 | 295.2 | In-house | 5-283 (293) | alignment | ||
Range on Protein: 573-847
Range on HMM: 5-283/293.0
QPLPLAQFPTFVNKN--RHTTLFSEEFHDLPGP-NIYPQTVAQEEINFKKNRYKNILPYDSVRVKLEVINDNPHSDYFNASYIPSFDNDKAYIASQGPNK
.|. | .| ..|.|. . . ||||...| . ...|....| .||||.|||||| ||||. ..|...||| ||.||| . . .||.|||
kpiklekfeehvkkmkadsdlrfseeyeelkavgkdqavkaaelavnraknrytnilpydhsrvkLaalkdesgsDYinanyipgynsprefiatqGPlp
ASMDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPgDSVKFGYIRVELVSLEACTGGIKRTMTMLKGDDCRTVTQFHFTEWPDKGVPKHTSALLK
..||||||||......| |.|.| |. |.|| .|||.. ..| .| |.|.||. | . . |.... |....|.|.|.||| ||| |||..|..||.
etvddfWrmvwekkssiivmltqlvekgkvkCeeYWPade.epvlyGdikvtlvaeeeledwvirelkiekekeerkvrqyhftsWpdhgvPektktlld
FIKEVKADH--GQYTHPLIIHCSAGVGRTGVVISIDSVVAHAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLE
|...|. . . ..|...||||||||||. |..| .. . ... .||.| .|...|..| ..|||..|| ||. .||.
fvrtvreaiektaskrPivvhCsaGvGRtGtfialdrllqaieeedyvdifgivaelReeRnllvqtekqYifihqcvld
|
|||||||||
subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 574-1088 | 0.0 | 1188.3 | In-house | 1-515 (515) | alignment | ||
Range on Protein: 574-1088
Range on HMM: 1-515/515.0
PLPLAQFPTFVNKNRHTTLFSEEFHDLPGPNIYPQTVAQEEINFKKNRYKNILPYDSVRVKLEVINDNPHSDYFNASYIPSFDNDKAYIASQGPNKASMD
||||||||.|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||.|
plplaqfPafvnknrhttlfseefhdlpgpniypqtvaqeeinfkknryknilPydsvrvklevindnPhsdyfnasyipsfdndkayiasqgPnkasvd
DFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPGDSVKFGYIRVELVSLEACTGGIKRTMTMLKGDDCRTVTQFHFTEWPDKGVPKHTSALLKFIKE
||||.|.||||||||||||||||||||||||||.|||||||||.|.|||||||||||||||..|.|||||.|||||||||||||||||||||.|||.|||
dfWrlvlqenvttiamvtklkegdkikcgkyWPdkpgdsvkfGsikvelvsleactggikrkltvlkgddsrtvtqfhfteWPdkGvpkhtssllklike
VKADHGQYTHPLIIHCSAGVGRTGVVISIDSVVAHAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLEDLLWRNTLIPVIHFTDHLQDLHSSGD
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||.||||||||||||||||||||||||||||||||||||||||||
vkadhgqythpliihcsaGvGrtGvvisidsvvahakttrmvdvfnfvtnirqkrpylvqtqeqyafiygavledllwrntlipvihftdhlqdlhssgd
GHGRSKMTKEFQTLKSLCPDPPASQTRSGRTRDNHPKNRYGNNLPLQRNRVILDSPDHDYINASQMKGIHCTFMTTQMPLPTTVSDFWSMVLNNKPSTIV
|.||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
grgrskmtkefqtlkslcpdppasqtrsgrtrdnhpknrygnnlplqrnrvildspdhdyinasqmkgihctfmttqmplpttvsdfwsmvlnnkpstiv
MLNDKSQNDKSCAQYWPDANSVQFGSYSVSTLSTSSDGDMTIRQLQVTRNSKRNRVILDSPDHDYINASNMKGVHCTFMTTQMPLPTTVSDFWSMVLNNK
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
mlndksqndkscaqywpdansvqfgsysvstlstssdgdmtirqlqvtrnskrnrvildspdhdyinasnmkgvhctfmttqmplpttvsdfwsmvlnnk
PSTIVMLNDKSQNDK
|||||||||||||||
pstivmlndksqndk
|
|||||||||
subfamily_PTPRA_pd | Subfamily PTPRA | 574-883 | 1e-89 | 295.7 | In-house | 13-329 (330) | alignment | ||
Range on Protein: 574-883
Range on HMM: 13-329/330.0
PLPLAQFPTFVNKN--RHTTLFSEEFHDLPGPNIYP-QTVAQEEINFKKNRYKNILPYDSVRVKLEVINDNPHSDYFNASYIPSFDNDKAYIASQGPNKA
|||. .. ... . || ||| || .| .|..| | .|||. |||||| || | |.. ...||| |||.| . . . .||.||| .
plpvekleeeirirsaddnklfreefnalPagpiqatlelaskeenkeknrvvnilPydfsrvilsvkeGveesdyinasfidGykekdkfiaaqGPkee
SMDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKpgDSVKFGYIRVELVSLEACTGGIKRTMTML-KGDDC-----RTVTQFHFTEWPDKGVPKHT
...|||||.|. . .|| |.|.||| .. || .|||.. .| .| ||||. . . | . . ..| . | |.||||| ||| ||| ..
tvedfwrmiweqksativmltelkerkeekcaqywPde..GlvtyGnirvevedetvlvdytvrkflvqqlpdatrekksrlvrqfhftswPdvGvPfep
SALLKFIKEVKADHGQYTHPLIIHCSAGVGRTGVVISIDSVVAHAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLEDLLWRNTLIPVIHFTDH
.||..|.||. . |.. |...|||||||||| | .|.|.. |. |.||||.|| ..|..|| ||||.||| ||| ..|| |. .| . |. . |
iGmlkllkkvkklnqqsagpivvhcsaGvGrtGtfivldavlervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvlleyylygdteldvsslekh
LQDLHSSGDGHGRSKMTKE
|| |... | . . .|
lqklynkitgtdkigleee
|
|||||||||
subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 575-869 | 9.6e-83 | 272.8 | In-house | 4-303 (305) | alignment | ||
Range on Protein: 575-869
Range on HMM: 4-303/305.0
LPLAQFPTFVNKNRHT--TLFSEEFHDLPGPnIYPQTVAQEEINFKKNRYKNILPYDSVRVKLEVINDNPHSDYFNASYIPSFDNDKAYIASQGPNKASM
. |... ......| . . . .... |. . | ..| | .|||.|.| ..| |..| .....||| ||||. .... |.||..||| | .
ialddlaayikearvysdkgleaqykslyee.eesidvgkkeankaknrlkeitlldddriiltekeslddsdyinasyvdgykrkkkyivaqgPlkntv
DDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPGDSVKFGYIRVELVSLEACTGGIKRTMTMLK---GDDCRTVTQFHFTEWPDKGVPKHTSALLK
.||||....| |.|| |.|||.||.| || .|||.. .....|| . ||| | .. .. |.| ... . .. |||.|...|.|||.|||. ...||.
adfWrliveekvstivmltklveggkdkCrqYWpesktekkefgefsvelksektasdyieRklkisiededkesrtvlqyqltdWPdhGvpqfatslls
FIKEVKADHGQYTH-PLIIHCSAGVGRTGVVISIDSVVAHAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLEDLLWRNTLIPVIHFTDHLQDL
.||.|. |. . ||..||||||||||| |..| . ..|. .||||. . ..|.||..||||..|| |.. |. | . .| | . .. ... |
likrvqkdqkkdkgvpllVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkmvqtldqYvflhdaldelitcgdtsiigsnlrarvnkl
H
.
k
|
|||||||||
subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 576-848 | 2.5e-65 | 215.2 | In-house | 3-282 (290) | alignment | ||
Range on Protein: 576-848
Range on HMM: 3-282/290.0
PLAQFPTFVNKN--RHTTLFSEEFHDLP-GPNIYPQTVAQEEINFKKNRYKNILPYDSVRVKLEVINDNPH--SDYFNASYIPSFDNDKAYIASQGPNKA
|. .| || .. . .. | ..|. | | . . ||. . | ..||..||..|| |. | |.... .| ||.|| . ..|.||| ||| .
pvdkfgefvanghakgnegfrnqfkmldsgesehtvtvgltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgykekkqyiatqgpvsn
SMDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKpgDSVKFGYIRVELVSLEACTGGIKRTMTMLKGDD---CRTVTQFHFTEWPDKG-VPKHTSA
. |||...|||.|| | |.|. .| .| || .|||.. |. ..|.....|.. |.... |.|.. . . . ...|||...| |...| |.....
tlvdFWkliwqekvtiivmltniieegkvkCqqYWpds..dtkaygefsikllneetlneyierklevknknsagakqsvtqyqitnwdstgkvtnpqti
LLKFIKEVKADHGQYTHPLIIHCSAGVGRTGVVISIDSVVAHAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLED
|| . . .| . . .....|||..|||..| .... . ..||. .|||. . . |...| .|||..|| .|. ||.
llvieemyktqrkrgntsivvHCSdtvgrsavfcaaattinkcktegvidvfqvlksqRiqkpgsvqtvqqyqgifqivlty
|
|||||||||
0040438 | (Phosphotyrosine protein) phosphatases II | 578-886 | 1.4e-88 | 292.6 | In-house | 6-313 (317) | alignment | ||
Range on Protein: 578-886
Range on HMM: 6-313/317.0
AQFPTFVNKNRHtTLFSEEFHDLPGPNIYPQTVAQEEINFKKNRYKNILPYDSVRVKLEVINDNPHSDYFNASYIPSFDNDKAYIASQGPNKASMDDFWR
.. ...|. . |...|||.||. .... .||. . | .||||..|||||. |||| ... ..||| ||||.. .. ...|| ||| . ...||||
llalldllksdf.talleefedllslkldtysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPlpntvedFwr
MVWQENVTTIAMVTKLKEGDKIKCGKYWPNkpGDSVKFGYIRVELVSLEACTGGIKRTMTML--KGDDCRTVTQFHFTEWPDKGVPKHTSALLKFIKEVK
|||...||.| |.|.|.| ...|| .|||. |.....| ..|.|.| | . | . ||... .....||||.||.| ||| |||.... ||.|...|.
mvweqgvtvivmLteleelgrekcaqYwpl..getltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavr
ADHGQYTHPLIIHCSAGVGRTGVVISIDSVVAHAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLEDLLWRNTLIPVIHFTDHLQDLHSSGDGH
. . .|...||||||||||..| .. .. . .... |||.. | .|..||..||| ||| |.| |.|| |....||.|. .. .|. |. ..
ealedpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleylkrkltlepaselklkllklliplald
GRSKMTKEFQT
. . ..||...
dvklkekelkl
|
|||||||||
subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 578-850 | 3.5e-64 | 211.5 | In-house | 5-279 (287) | alignment | ||
Range on Protein: 578-850
Range on HMM: 5-279/287.0
AQFPTFVNKNRH--TTLFSEEFHDLPGPNIYP--QTVAQEEINFKKNRYKNILPYDSVRVKLEvindNPHSDYFNASYIPSFDNDKAYIASQGPNKASMD
.| ||.|... . |.. | | . . |.. . | .|||...||..| || |. . | || ||..| .. ..||.|....| .
ekfgefvakghakgnegfknqftvleqvtqredevthniasqnkdknRltqilvpdnyrvllk....gehpdyinavfidgykekkafiiaesPmfntar
DFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKpgDSVKFGYIRVELVSLEACTGGIKRTMTMLK---GDDCRTVTQFHFTEWPDKG-VPKHTSALLK
.||......|||.| |....|| |. .| .|||.. .|| .| ..||.. | .| |.|.. . . .| ..|.|...|.|...| |... . ||
nfWkliddrnvtaivmlcqekendeevcyqyWpee..ksvvlGeyniellneevnagyierklevknknkagdkqqvkqyqitnWdstgkvtepqtillv
FIKEVKADHGQYTHPLIIHCSAGVGRTGVVISIDSVVAHAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLEDLL
. . .|... . ....|||..|||... .... . ..|| .|||. . . |...| .||| ||| ||. .||| |
ieemyktqrkrgntsivvhCsdtvGrsamfcaaattinkckteGviDvfqvlksqriqkpgsvqtveqykfindivleyld
|
|||||||||
0047943 | (Phosphotyrosine protein) phosphatases II | 582-847 | 2.9e-85 | 281.3 | In-house | 3-270 (273) | alignment | ||
Range on Protein: 582-847
Range on HMM: 3-270/273.0
TFVNKNRHTTLFSEEFHDLPGPN-IYPQTVAQEEINFKKNRYKNILPYDSVRVKLevinDNPHSDYFNASYIPSFDNDKAYIASQGPNKASMDDFWRMVW
...| ..||. |||..|. ... .||. . |..|||||.|||||. |||| ....||| ||||.. .. ...|| ||| . ...|||||||
lllekllgltllleefelllslkplltysvallpenkdknrykdilpydhsrvkl....gdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvw
QENVTTIAMVTKLKEGDKIKCGKYWPNKPGD-SVKFGYIRVELVSLEACTGGIKRTMTMLK--GDDCRTVTQFHFTEWPDKGVPKHTSALLKFIKEVKAD
..||..| |.|.| | ...|| .|||.. |. |...| ..|.|.| | . . ..||... . ...||||.||.|.||| ||| ... ||.||..|.
eqnvrviVmLtelvelgrekcaqYwpleggelsltygkftvtllseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvrka
HGQ--YTHPLIIHCSAGVGRTGVVISIDSVVAHAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLE
. . .| ..||||||||||..| .| .. . .....|||.. | .|..||.|||| ||| |.| |.||
lealpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyealle
|
|||||||||
0039614 | (Phosphotyrosine protein) phosphatases II | 582-854 | 4.2e-82 | 271.2 | In-house | 23-294 (297) | alignment | ||
Range on Protein: 582-854
Range on HMM: 23-294/297.0
TFVNKNRHTTLFSEEFHDLPGPNIyPQTVAQEEINFKKNRYKNILPYDSVRVKLEVINDN-PHSDYFNASYIPSFDN-DKAYIASQGPNKASMDDFWRMV
...| .||. .|| .|. .. ....|. . | .|||||.|||||. |||| .... ..||| ||||.. .| ....||.|||.. ...||||||
lllekansktllllefeellslkp.dysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIatqgPlpetvedFwrmv
WQENVTTIAMVTKLKEGDKiKCGKYWPNKPGdsvKFGYIRVELVSLEACTGGIKRTMTMLKGDDCRTVTQFHFTEWPDKGVPKHTSALLKFIKEVKADHG
|...||.| |.|||.| .. || .|||.. | ..| ..|.|.. | . | . ||... ... ||||.|..| ||| ||| ... ||.|...|. .
weqgvtvivmLtklvelgr.kcaqywpeegg...tygdftvtllkvehldgytvrtlevtnngesrtvthfqytgwpdhgvppslellleflelvreala
Q--YTHPLIIHCSAGVGRTGVVISIDSVVAHAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLEDLLWRNT
. .| ..||||||||||..| .. .. . .... |||.. | .|..||..||| .|| |.| |.|| |....|
elpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydallellkrklt
|
|||||||||
subfamily_PTPN9_pd | Subfamily PTPN9 | 582-847 | 8.2e-72 | 236.7 | In-house | 8-288 (297) | alignment | ||
Range on Protein: 582-847
Range on HMM: 8-288/297.0
TFVNKNRHTTLfSEEFHDLPGPNIYP-QTVAQEEINFKKNRYKNILPYDSVRVKLEVINDNPHSDYFNASYIPSFDNDKAYIASQGPNKASMDDFWRMVW
..|..... | |.|. .. .. .... | .||||...| ||. ||.|. ......||| ||... . . ||.|| ||| | ..|||||||
ayvkekgkrGl.skeyaeirnepveGtflasklranleknrytdvlcydetrvvlakvdedeasdyinanfvdGykqkkafiatqGplkktvsdfWrmvW
QENVTTIAMVTKLKEGDKIKCGKYWPNKPGDSVKFGYIRVELVSLEACTGGIKRTMTML--KGDDCRTVTQFHFTEWPDKGVPKHTSALLKFIKEVKADH
...| .| |.|.. | ..|||.|||.. ..| .|| ..|. |. | .|.... | .. |.|| | |. ||| |||. ...||.....|.
eqevlvivmttrvvergrlkcgqyWpleeessaefgdlsvsnveveeeedykvrvleiknvkteesrkvthfqflsWPdyGvPssaaslldvlekvrekq
GQYT-------------HPLIIHCSAGVGRTGVVISIDSVVAHAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLE
.. . |...|||||.|||| |..| ... ... .|||.. | .|..| ...||.|||.| | ||||
alavkelgdewkghpsgPPivvhcsaGiGrtGtfitldiclsrleevgtvdvvetvkllrtqrafsiqtpeqyefcylavle
|
|||||||||
0045450 | (Phosphotyrosine protein) phosphatases II | 583-847 | 5e-81 | 268.1 | In-house | 19-302 (307) | alignment | ||
Range on Protein: 583-847
Range on HMM: 19-302/307.0
FVNKNRHTTLFSEEFHDLPGPNI---YPQTVAQEEINFKKNRYKNILPYDSVRVKLEVINDN-PHSDYFNASYI--------PSFDNDKAYIASQGPNKA
.... . |.. .||..|. .. .. ..|. . | .|||||.|||||. |||| ..... ..|||.||||. ...|.....|| ||| .
llllldfltgllkefekllsvtvfllgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydlkrkfIatqgPlpe
SMDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKpGDSVKFGYIRVELVSLEACTGGIKRTMTML---KGDDCRTVTQFHFTEWPDKGVPKHTSAL
...|||||.|...||.| |.|.|.| ...|| .|||.. |... .| ..|.|.| | . | . ||... . . ||||.||.|.||| |||.... |
tvedFwrmlweqgvtvivmltelvelgrekcaqywPde.geeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfeel
LKFIKEVKADHGQ--YTHPLIIHCSAGVGRTGVVISIDSVVAHAKTTRM---VDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLE
|.||.||.. ... .| ..||||||||||..| .. . . ... . ||... | .|..|| .||..||| |.| |.||
ldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyealle
|
|||||||||
subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 584-854 | 9.3e-86 | 282.7 | In-house | 20-295 (298) | alignment | ||
Range on Protein: 584-854
Range on HMM: 20-295/298.0
VNKNRHTTLFSEEFHDLPGPNI----YPQTVAQEEINFKKNRYKNILPYDSVRVKLEVINDNPHSDYFNASYIPSFDNDKAYIASQGPNKASMDDFWRMV
|.|. . | ...||. | . ..||... | ||||| .|...|| || || .... .||| |||.. .... .|.||.|.| .... ||||||
vkkkkkltgyalefqrlnsvsseieeeekevarkpenkkkNRyadiialdssRvvLekedadeesdYiNAsflhaykgrnafiatqaPltetvedFWrmv
WQENVTTIAMVTKLKEGDKIKCGKYWPNKpgDSVKFGYIRVELVSLEACTGGIKRTMTMLKGD--DCRTVTQFHFTEWPDKGVPKHTSALLKFIKEVKAD
..|...|| |.|.|.| ||.|. ||||.. . ..| |.|.| | | . |.|.... | . . |.| |.|||.|||||||......|.....|.|
teedigtiVmltnleeldktkyhkywPde..gketygeitvsllskeefadlivrklkvskkkeekerevrqlhftsWpdkgvpenatsvldllrkvras
HGQYT-HPLIIHCSAGVGRTGVVISIDSVVAHAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLEDLLWRNT
. | .|.|..|||||||.| | ||||. ..|. ..||||. | .|.||| .|||.|||.||| |||| | |.
qqqagnkpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavlealdsfnd
|
|||||||||
subfamily_Ptp69D_pd | Subfamily Ptp69D | 584-868 | 1.6e-83 | 275.4 | In-house | 14-305 (307) | alignment | ||
Range on Protein: 584-868
Range on HMM: 14-305/307.0
VNKNRHT-TLFSEEFHDLPGPNIYPQT-VAQEEINFKKNRYKNILPYDSVRVKLEVINDNPHSDYFNASYIPSFDNDKAYIASQGPNKASMDDFWRMVWQ
....|.| .. .|.. |. .| .| |.... | ||||..| ..|. ||||..|| . .||| |||.| .... | .||.|.| | ..|||||...
ksrkrdtdfglakeyekLeareidkstkvsekkenalknRyedikafDktRvkLkkingkedsdYinasfikgykekkkfiaaqdPveatigDfWRmiae
ENVTTIAMVTKLKEGDKIKCGKYWPNKpgDSVKFGYIRVELVSLEACTGGIKRTMTMLKGD-------DCRTVTQFHFTEWPDKGVPKHTSALLKFIKEV
.||.| |...|.| .. || ||||. | |..| | |.||| | .. |.|.. . | . | | |.|.|.|.|.| ||... .|||.|..|
qevtlivmlsnlteknrkkcakYWpie..devqygdilvklvseekhsdyiiReldvskkkeesgevedsrkvvqyhytgWkDskvPevargllklieqv
KADHGQYTHPLIIHCSAGVGRTGVVISIDSVVAHAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLEDLLWRNTLIPVIHFTDHLQDL
. . . |...||||||||.|.....||.. . |. ||.|..| ..|..|. .|| ||| |.| |.|. . .| . | .. |... |
relyklnrsPivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnllvqsleqYvflyralldyssygdtdedvddledaierl
|
|||||||||
subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 585-862 | 2.6e-58 | 192.5 | In-house | 15-292 (439) | alignment | ||
Range on Protein: 585-862
Range on HMM: 15-292/439.0
NKNRHtTLFSEEFHDLPG--PN-IYPQTVAQEEINFKKNRYKNILPYDSVRVKLEVINDNPHSDYFNASYIPSFDNDKAYIASQGPNKASMDDFWRMVWQ
.||.. .|.|.|. . |. ..| .| . |||||.. ..| || |. | ||| |.|| || . .|| |||.|||.| . |||||.|..
dknkq.eifkeifekinstspdyaciaslaaqeydqtknrykdvgafdhtrvtlqeipgvphshyinanyikGyyddklyiatqgpkkettddfwrlvie
ENVTTIAMVTKLKEGDKikcgkYWPNKpgDSVKFGYIRVELV---SL-EACTGGIKRTMTMLKGDDCRTVTQFHFTEWPDKGVPKHTSALLKFIKEVK-A
....|| |.|.| | | ||| . . | .| | | | . . |.| ... ||| |||.. |||| || ..| .|.|.. .. |
kktvtivmltnlvesyk.....ywpsd..aevcygdiavrvdrnielpnyvirgfkvfnerdttekertvlqfhyiawpdknvpaqashvldflrainsa
DHGQYTHPLIIHCSAGVGRTGVVISIDSVVAHAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLEDLLWRNTLIPVIHFT
. . . |...|||||||||| .|..| . . |. ||. |. .|..| |||. || ||| |||||. . .. . . .|
ndkeeygpvvvhcsagvGrtGtiialdialeqlklenkvdikgivkvlrkqrkqmvqalcqyvfiynavledivyGdiavtidefk
|
|||||||||
0036941 | (Phosphotyrosine protein) phosphatases II | 586-860 | 2.5e-85 | 281.7 | In-house | 9-288 (297) | alignment | ||
Range on Protein: 586-860
Range on HMM: 9-288/297.0
KNRHTTLFSEEFHDLPGPNIYPQTVAQEEINFKKNRYKNILPYDSVRVKLevinDNPHSDYFNASYIPSFDNDKAYIASQGPNKASMDDFWRMVWQENVT
.. . | .| . || .... .||. . | .|||||.|||||. |||| |...|||.||||.. .| ....|| ||| . ...|||||||..|||
llflalllkefeellpllllgslsvallpenleknRykdilpydhtRVkl....ddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqnvt
TIAMVTKLKEGDKIKCGKYWPNKPGDSVKFGYIRVELVSLEA--CTGGIKRTMTMLK--GDDCRTVTQFHFTEWPDKGVPKHTSALLKFIKEVKADHGQ-
.| |.|.| | ...|| .|||.. |.|...| ..|.|.| | ... . ||..... ... ||||.||.| ||| ||| ... ||.||..|. . .
vIvmltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrkvlkll
-YTHPLIIHCSAGVGRTGVVISIDSVVAHAK---TTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLEDLLWRNTLIPVIH
.| ..||||||||.|..| .| .. . ... ||....| .|..|| .||| ||| |.| |.|| |....| .|..
psggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallellkkkltkepllk
|
|||||||||
subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 586-846 | 4e-85 | 280.4 | In-house | 16-276 (288) | alignment | ||
Range on Protein: 586-846
Range on HMM: 16-276/288.0
KNRHTTLFSEEFHDLPG-PNIYPQTVAQEEINFKKNRYKNILPYDSVRVKLEVINDNPHSDYFNASYIPSFDNDKAYIASQGPNKASMDDFWRMVWQENV
. | | ||||.. |. . .|.... | |||||.|||||| ||||. .... .|| ||||| . ...|.|||.|||. ....|||..|.....
sarnrtgfseeynsLaalektksvtagrlavnakknRyrnilpyDekrvklkkleeeagaDYinasyidgekkkkkyiatqgPladtvndfWelvyenkt
TTIAMVTKLKEGDKIKCGKYWPNKpGDSVKFGYIRVELVSLEACTGGIKRTMTMLKGDDCRTVTQFHFTEWPDKGVPKHTSALLKFIKEVKADHGQYTHP
.||.|.|.| ||.| ||..|||.. .. ...| . |.||. . . ..|.. . | . ...||.... |||.|||. . ||.... || . . | |
stivmltelveggktkCeeYWPda.dkpknyGsvtvtlveskeledfvlrklllekkkteleitqyqylaWpdhgvPeskapllellrqvkvanqadtgp
LIIHCSAGVGRTGVVISIDSVVAHAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVL
.|.||||||||||. |..| .. . ... ..||...|...|..|. .|||..|| ||| ..|
iivhCsaGvGrtgtFialdalidaveeedyiDvagtvaklRkqRallvqtlkqYefiyevll
|
|||||||||
0051299 | (Phosphotyrosine protein) phosphatases II | 587-847 | 1.6e-90 | 298.7 | In-house | 19-284 (288) | alignment | ||
Range on Protein: 587-847
Range on HMM: 19-284/288.0
NRHTTLFSEEFHDLPGPNI-YPQTVAQEEINFKKNRYKNILPYDSVRVKLEVINDNPHSDYFNASYIPSFDNDKAYIASQGPNKASMDDFWRMVWQENVT
...|.. |||..|. .. .....|. . |..||||..|||||. |||| |......||| |||||. .......|| ||| . ...|||||||..||.
angltglleefeellsllpdltlsaallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyidgynlkrkfIatqgPlpntvedFWrmvweqnvr
TIAMVTKLKEGDKIKCGKYWPNkpGDSVKFGYIRVELVSLEACTGGIKRTMTML------KGDDCRTVTQFHFTEWPDKGVPKHTSALLKFIKEVKADHG
.| |.||| | ...|| .|||. |.|...| |.|.|.| | . . ..||... ... .||||.||.| ||| ||| ....||.|...|. .
vIvmltklvelgrekcaqYwpl..ggsltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdspellldflrlvrkala
QYTHPLIIHCSAGVGRTGVVISIDSVVAHAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLE
. .| ..||||||||||..| .| .. . .....|||...| .|..||.|||| ||| |.| |.||
sgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyealle
|
|||||||||
subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 587-884 | 4.7e-76 | 251.0 | In-house | 19-323 (325) | alignment | ||
Range on Protein: 587-884
Range on HMM: 19-323/325.0
NRHTTLFSEEFHDLPGPNIYPQTVAQEEINFKKNRYKNILPYDSVRVKLEVINDNPHSDYFNASYIPSFDNDKAYIASQGPNKASMDDFWRMV--WQenv
. |. || || . ..|| | .|||.||....| || || .|.|.|||.||||. .. . . ..|.| |. |...|.||.| |.
aqdqdgfahefgllpsddgiakkvamkpenkaknrfknvvaldksrvvletkkddpssdyinasylrddkkkdvflaaqaPltatindlWrlvldWr...
TTIAMVTKLKEGDKIKCGKYWPNKPGDSVKFGYIRVELVSLEACTGGIKRTMTM--LKGDDCRTVTQFHFTEWPDKGVPKHTSALLKFIKEVKADHGQYT
... .|. ...| .| .|||.. |.|..|| ..|.|...| . ..| . . |. . |.| ||.. |.| ||.|. ..|. ... ||| . . |
csvvvvlneldlgkdrcavywpkemgksktfGglevklrtieeisdyvhrvldvkqvkkGetrsvkqfqlqswddmGvqkrpatlisilqlvkavservt
H------PLIIHCSAGVGRTGVVISIDSVVAHAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLEDLLWRNTLIPVIHFTDHLQDLHSSGDGHG
|...||||||||||| ||. |..|. . ||.|.|| ..|..|| ||.| .|| .|| |. | .. || .|| | .| |.
antkastpilvhcsaGvGrtGvfislysalakvieesrvdifgfvkklrkdrpsmvetvdqyiliyealveaymsgntdvpvssfeaklsslqernpltq
RSKMTKEF
. .. |||
klniekef
|
|||||||||
subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 587-858 | 4.8e-59 | 194.6 | In-house | 5-275 (283) | alignment | ||
Range on Protein: 587-858
Range on HMM: 5-275/283.0
NRHTTLFSEEFHDLPGPNIyPQTVAQEEINFKKNRYKNILPYDSVRVKLEVINDnphsDYFNASYIP---SFDNDKAYIASQGPNKASMDDFWRMVWQEN
. || | .. | |. . ..| . | .|||...|.|.| ||.|. . || ||..|| | ..|| ||..|.| . . |||.||..|.
vnnnklfrevlkrlsvpdl.dadiasadenkrknrnqeivpadqwrvelksesr....dyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdek
VTTIAMVTKLKEGDKIKCGKYWPNKpgDSVKFGYIRVELVSLEACTGGIKRTMTMLKG---DDCRTVTQFHFTEWPDKGVPKHTSALLKFIKEVKADHGQ
.|.| |.|||.|. .||| .|||.. |...| | | . |.. ... . . .. . . .| . | .|.|| | . .
itaivmltklqedlrikCsqyWPkr..GsedyGeftvtlrkettsnsfiikelllrvnssakstlllahyqvidWleygeqaiinslvkfnkvislqtes
YTHPLIIHCSAGVGRTGVVISIDSVVAHAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLEDLLWRNTLIPV
|...|||.|.|||.| |.. . | .|.| .||||. |...|..|. .|||..|| ... .|||. | .| |
kkgPivvhCstgiGrtavfiaasasvkdaltesvvdvfavvkimreqrmmavqtldqyklvhelvleqalcgdtqiaa
|
|||||||||
subfamily_CG7180_pd | Subfamily CG7180 | 587-850 | 7.2e-58 | 190.5 | In-house | 13-291 (296) | alignment | ||
Range on Protein: 587-850
Range on HMM: 13-291/296.0
NRHTTLFSEEFHDLPGPNIYPQTVAQEEINFKKNRYKNILPYDSVRVKLEVINDNPHSDYFNASYIPSFDNDKAYIASQGPNKASMDDFWRMVWQENVTT
... .. |.. | .| . .. | .|||. ...||| || || .. . .||| ||.|. || .|.|| ..| | ..|.|||.|..|.. .
rkfrveyklelkltprleigdCagglrkenreknrdvkvvPyDynRvvLekldGeeksdYinavyvdsflkkkeyivteapkketvdefWrlvydeeisa
IAMVTKLKEGDKiKCGKYWPNKPgdSVKFGYIRVELVSLEACTGGIKRTMTMLKG------------DDCRTVTQFHFTEWPD-KGVPKHTSALLKFIKE
. ..|| . | .. .||||| ..| | ||.|. . . .||. . | . |.|..|..|||. . || |.||.....
vvvLtktfdfak.mypsywpnks..keqygeifveiveekqyanlkirtfkltkkivalteqekqvkaetRivklfqlteWeledkvPlstnalielrrr
VKADHGQY-----THPLIIHCSAGVGRTGVVISIDSVVAHAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLEDLL
|. .. . |.....| |..|.|| ..|| . .. . ||||..| .|..|| .|.. |.| .|| .|| .|
vrlwrekvdedpeegPvvvvssdGasRsGvylaidanlelvekeeevdvFeavktlrrsRpqLvenveeYkyiYdvlleavl
|
|||||||||
subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 587-848 | 4.7e-56 | 184.7 | In-house | 11-292 (301) | alignment | ||
Range on Protein: 587-848
Range on HMM: 11-292/301.0
NRHTTLFSEEFHDLPGPNIYPQTVAQEEINFKKNRYKNILPYDSVRVKLEVIN--DNPHSDYFNASYIPSFDNDKAYIASQGPNKASMDDFWRMVWQENV
. |.. |.|....| . . || .| | . ||.||| .|| |. |. . | . .| ||||| .. . |..||.||| | . ||||..||| .
akhsnkfeeqykelkegedksctvglseenkalnrfknitvyddnriilkpkpnldlcqreyinasyidgysekkkfiaaqgpmkktlvdfWrliwqekp
TTIAMVTKLKEGDKIKCGKYWPNKPGDSVKFGYIRVELVSLE-----------------ACTGGIKRTMTMLKGDDCRTVTQFHFTEWPDKGVPKHTSAL
..| |||.|||| | || .|||| .| .|| . |.||. . | |.|.. . . . ..|.|.. |.||. || .
vsivmvtnlkegtkskceqywpnseaeseefgpftvtlvneqvyPdfvirqlnvkiqdgsnngyierkfkvksdksswdvlqlqvtdWpqdGvvreprtv
LKFIKEV-KADHGQYTHPLIIHCSAGVGRTGVVISIDSVVAHAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLED
|. | .| .. . |...|||..|.|.|| .|.. . .| ||||. . .|...| .|.| ||| .|| .. .
LqviddvihrqqkigggpvvVHCSdtVsrsGvYcsvsiglEQckaegVVdvfqvtkavrrskpgaVtTLeqytsiydvidmy
|
|||||||||
subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 588-885 | 1.5e-85 | 282.1 | In-house | 20-319 (319) | alignment | ||
Range on Protein: 588-885
Range on HMM: 20-319/319.0
RHTTLFSEEFHDLPGPNIYPQTVAQEEINFKKNRYKNILPYDSVRVKLEVINDNPHSDYFNASYIPSFDNDKAYIASQGPNKASMDDFWRMVWQENVTTI
.||. .||..| ... . |..|.| |||||.|||.|| ||.| ... . ||| |||.| .... ...|| |.| . ..|||||||.|.. ..
tgetllekefkllkeavndtfdsaskeenkkknryqnilaydrtrvvlseldgvegsdyinasfidgyqerekfiatqaPlentiedfWrmvWeeessiv
AMVTKLKEGDKIKCGKYWPNKpgDSVKFGYIRVELVSLEACTGGIKRTMTML-KGDDC--RTVTQFHFTEWPDKGVPKHTSALLKFIKEVKAD-HGQYTH
|.|||.| |.|. ||||.. . ...| . |.| . | . |.| ... | .. |.|..|..|||||..||... .||...|... ...
vmltklveklkvklkkywpee..nfeeyGrlivtleeeeeledyiirklklnkkssevetRevkhfqyteWpdhdvPekatslldllkrirksrektqsg
PLIIHCSAGVGRTGVVISIDSVVAHAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLEDLLWRNTLIPVIHFTDHLQDLHSSGDGHGRSKMTKE
|...|||||||||| | .| .. . | ..|||..| ..| .|. |||..||| ||| |.|| . .| | | .. | |..| . . | ... .|
PivvhCsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyealleaveagdteievqdlrdrlkqlaekvadtgetglere
FQ
||
fq
|
|||||||||
0043336 | (Phosphotyrosine protein) phosphatases II | 588-847 | 4.1e-82 | 271.1 | In-house | 17-275 (278) | alignment | ||
Range on Protein: 588-847
Range on HMM: 17-275/278.0
RHTTLFSEEFHDLPGPNIYPQTVAQEEINFKKNRYKNILPYDSVRVKLEVINDNPHSDYFNASYIPSFDNDKAYIASQGPNKASMDDFWRMVWQENVTTI
||...||..|. .......|. . |..|||||.|||||. ||||.... ..||| ||||.. .. ...||.|||.. ...|||||||...||||
nlktllllefeellsfkldtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpetvedFwrmvwelgvtti
AMVTKLKEGDKIKCGKYWPnkpGDSVKFGYIRVELVSLEACTGGIKRTMTML--KGDDCRTVTQFHFTEWPDKGVPKHTSALLKFIKEVKADHGQYTHPL
|.|.|.| ...|| .||| |.|...| ..|.|.. | . . . ||... . . .||||..|.. ||| ||| ..| ||.|.|.|. .|.
vmLtelvelgrvkcaqYwp...ggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldflkavrealedsngpv
IIHCSAGVGRTGVVISIDSVVAHAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLE
..||||||||||..| .. .. ...... ||... | .|..|| .|||..|| |.| |.||
lVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyealle
|
|||||||||
subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 589-887 | 2e-91 | 301.4 | In-house | 18-318 (318) | alignment | ||
Range on Protein: 589-887
Range on HMM: 18-318/318.0
HTTLFSEEFHDL-PGPNIYPQTVAQEEINFKKNRYKNILPYDSVRVKLEVINDNPHSDYFNASYIPSFDNDKAYIASQGPNKASMDDFWRMVWQENVTTI
..|.|||.. | . .. .. . |..| .|||| |||.||. ||||. ..... ||| ||.||. . ..|||||.|.| ..|||||||. | ..|
GelllseeyerlsrseetvtslkslepvnkaknryanilaydhtrvkLqmlegeegsDyinanyidGyrrkkayiaaqaPlpetieDfWrmvWeqnsavi
AMVTKLKEGDKIKCGKYWPNKpgDSVKFGYIRVELVSLEACTGGIKRTMTML--KGDDCRTVTQFHFTEWPDKGVPKHTSALLKFIKEVKADH-GQYTHP
|.|...| |.|. .|||.| .| ..| ..||| . .. . |.... . .. |.| |.|.|.|||.|||.... ||.....|.. . . ..|
vmltqeeergkakvhryWPsk..gsrsygklvvelkeevelsdyvlrefkvtrteeeesrqvrqyhytsWpdegvpesgaslldlvrqvskaqqksgagp
LIIHCSAGVGRTGVVISIDSVVAHAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLEDLLWRNTLIPVIHFTDHLQDLHSSGDGHGRSKMTKEF
...||||||||||| | .|... ..| .||||..|...|..|. ||||..|| ||| ..|| | .| . ........|. . |...| ||
ivvhCsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqtedqyefiydvllealasgdtevdasdlrsrirelreqdpesgttemdaef
QTL
| |
qrl
|
|||||||||
subfamily_PTPN6_pd | Subfamily PTPN6 | 589-846 | 1.2e-73 | 242.8 | In-house | 24-294 (306) | alignment | ||
Range on Protein: 589-846
Range on HMM: 24-294/306.0
HTTLFSEEFHDLP---GPNIYPQTVAQEEINFKKNRYKNILPYDSVRVKLEvINDNPHSDYFNASYIP--SFDNDKAYIASQGPNKASMDDFWRMVWQEN
. . |.|||..| . . .. .. | .|||||||||.| ||.|. .. | ||| ||.|| . ..||.|||.|| .. . ||||||||||
ekagfeeefeelqqeeakkllsrkegakpenkeknryknilPfDhtrvilk.epsvpgsdyinanyikkevkgsdksyiatqgclettvsdFWrmvwqen
VTTIAMVTKLKEGDKIKCGKYWPNKPGDSVkFGYIRVELVSLEACTGGIKRTMTML---KGDDCRTVTQFHFTEWPDKGVPKHTSALLKFIKEVKADHGQ
. | |.|| | | || .|||.. .. .| |.|. || .. . | |.... |....|.| |.||..|||.||||...|.|.|...|.. . .
srvivmttkevErgkekCarYWPdeeekee.yGkisvtnvseksladYilRelsvskkkkkkeerevfqyhfksWPdhgvpkdpgavLdfledvnrkqee
YT----HPLIIHCSAGVGRTGVVISIDSVVAHAKT---TRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVL
. |...|||||.|||| .| || .. .. .|. ..| .|. | .|||..|| |.| |.
leeaeagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqteqqykfvykaik
|
|||||||||
subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 591-849 | 1.9e-81 | 268.3 | In-house | 15-276 (281) | alignment | ||
Range on Protein: 591-849
Range on HMM: 15-276/281.0
TLFSEEFHDLPG-PNIYPQTVAQEEINFKKNRYKNILPYDSVRVKLEVINDNPHSDYFNASYIPSFDNDKAYIASQGPNKASMDDFWRMVWQENVTTIAM
. | ||...| . . | .... | .||||.|| || |||.. ..| ..|| ||...|.....|.|||.||| ||...||.|||...|..|.|
aGfieeyeklaaigvdntataskadenvlknrYsnivaYDatrvkvtpneenkntDYinanfvpgykgekeyiatqgPvPaslvafWqmvweqkvsaivm
VTKLKEGDKIKCGKYWPnKPGDSVKFGYIRVELVSLEACTGGIKRTMTM-LKGDDCRTVTQFHFTEWPDKGVPKHTSALLKFIKEVKADHGQYT-HPLII
||. |..|.|| .||| . ..|.| ..|. .. |. . |.|.... .. . |.|.|...| |||.|||. |..||.| |||. . . | .||.|
vtreieagklkChrYWP.ddnselkygdvtvkstaeeekatyierkfkleresgetreveqlaytaWPdhGvPattkellefrkevlkltekktkaplvi
HCSAGVGRTGVVISIDSVVAHA-KTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLEDL
||||||||||. |..| .| .. ......|| . |...|..| .|||| ||.|.| |||. |
hCsaGvGrtGtyialDrlvkaveaeleeldvkavvaelrkernlmvqtvvqyefvykavldal
|
|||||||||
subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 591-846 | 5.5e-68 | 224.0 | In-house | 5-265 (274) | alignment | ||
Range on Protein: 591-846
Range on HMM: 5-265/274.0
TLFSEEFHDLPGpNIyPQTVAQEEINFKKNRYKNILPYDSVRVKLEV-INDNPHSDYFNASYIPSFDN-DKAYIASQGPNKASMDDFWRMVWQENVTTIA
. . .|| .|| | .| . . .|||||.||| . || || .... |.| || || .|. .|||.| ||| ..|||||..||.|. |
kdlekeflelPl.nf.dqeeldvfgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqviv
MVTKLKEGDKIKCGKYWPNKPGD--SVKFGYIRVELVSLEACTGGIKRTMTMLKGDDCRTVTQFHFTEWPDKGVPKHTSALLKFIKEVKADHGQYTH---
|.||||| .. || .|.|.. . | ..| . .. .. . . |...... ..|.|. . .|.|||. .|.....||....||. .. . ..
mltklkeaneqkCavyfPdaedyeiserygdveikvekiverndysvrklvlkylerersvkhywytdWPdhksPddantlldlvleveesreeenakla
PLIIHCSAGVGRTGVVISIDSVVAHAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVL
| ..|||||.||||. |.|. | . . . .|||.. |.|.|..| ||||.||| .|. |.
pvvvhCsaGiGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralc
|
|||||||||
subfamily_PTPRG_pd | Subfamily PTPRG | 592-853 | 7.6e-75 | 247.2 | In-house | 20-291 (563) | alignment | ||
Range on Protein: 592-853
Range on HMM: 20-291/563.0
LFSEEFHDLPG---PNIYPQTVAQEEINFKKNRYKNILPYDSVRVKLEVINDNPHS-DYFNASYIPSFDNDKAYIASQGPNKASMDDFWRMVWQENVTTI
|||||..| .. . . .|.. | .|||| ||..||. ||||. . .. .. || ||.|| . ||.||.||| | .||||||.|..||..|
gfseefealqsetiskdldaehsqkpenkrKnRylnivaydrsRvklsplpgkkkklDYinAnyidGyqkskafiatqgplkdtfddFWrmiWeqnvaii
AMVTKLKEGDKIKCGKYWPNkpGDSVKFGYIRVELVSLEACTGGIKRTMTMLK-----GD---DCRTVTQFHFTEWPDKGVPKHTSALLKFIKEVKADHG
|.|.|.| . || |||. .|...| ..| |.. | . .||... . .. . ..|.|.|.|.|||.|||.|. |.|.| .| .
vmitnlvergrrkcdvYWPk..desetygalqvtlieeevlalytvrtlviknlklkkkkqcdteklvrqyhytkWPdhgvPehslpvLifvkkssaank
QYTHPLIIHCSAGVGRTGVVISIDSVVAHAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLEDLLWRN
. . |...||||||||||. | .|... .. .|.||.|. || .|...|||.||| |.. |.|| .. ..
aeaGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvqteEqYiflhdalleaiaske
|
|||||||||
0045098 | (Phosphotyrosine protein) phosphatases II | 592-851 | 1.2e-71 | 236.6 | In-house | 9-274 (278) | alignment | ||
Range on Protein: 592-851
Range on HMM: 9-274/278.0
LFSEEFHDLPGPNIYPQTVAQEEINFKKNRYKNILPYDSVRVKlevindnphsDYFNASYIPSFdnDKAYIASQGPNKASMDDFWRMVWQENVTTIAMVT
|..| .. |. .... |.|. . |..|||||.|||||. ||| || |||||... .|..|| ||| . ..|||||.|....|.| |.|
lllefefllllgipseitpalylgnldknRykdilpydhsrVk..........dYINAsyidgy..pkkfIatqgPlpstvadfwrmlwelgitvivmlt
KLKEGDKIKCGKYWPNkpGDSVKFGYIRVELVSLEACTGGIKRTMTML------KGDDCRTVTQFHFTEWPDKGVPKHT--SALLKFIKEVKADHGQ---
.|.|....|| .|||. |.|. .| ..|.|.| | . ..||... ... .|.||..|.. ||| ||| .. . .|........ . .
elvelgrekcaqywpe..ggsltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllas
----------YTHPLIIHCSAGVGRTGVVISIDSVVAHAktTRMVDVFNFVTNIRQKRPY-MVQTQEQYAFIYGAVLEDLLW
.| ..||||||||||... .. . . . ||... |. .|..||. .||..||| |.| ..|| ||.
lllsslllldsggpvlVHCsaGvgRtGtlvaaylmlell..eggvdlleavkelrsqRpglavqnleqyrflyefllelllr
|
|||||||||
subfamily_Sponge-PTP3_pd | Subfamily Sponge-PTP3 | 592-666 | 6.8e-12 | 39.4 | In-house | 24-95 (95) | alignment | ||
Range on Protein: 592-666
Range on HMM: 24-95/95.0
LFSEEFHDLPGPNIYPQTVAQEEINFKKNRYKNILPYDSVRVKLEVINDnphSDYFNASYIPSFDNDKAYIASQG
| .||. .. | || | | |||. ||.|||. || | | ||| || .. . ..|||.||
efdnefksismtsgapytvgsseanipknrflnifpydatrvvlttkrd...sdyinacfvdgyarkncyiaaqg
|
|||||||||
subfamily_PTPRK_pd | Subfamily PTPRK | 593-886 | 3.1e-83 | 274.2 | In-house | 24-314 (314) | alignment | ||
Range on Protein: 593-886
Range on HMM: 24-314/314.0
FSEEFHDLPGPniypQTVAQEEINFKKNRYKNILPYDSVRVKLEVINDNPHSDYFNASYIPSFDNDKAYIASQGPNKASMDDFWRMVWQENVTTIAMVTK
| ||. |. .|... | .|||...||.|| ||.| .|...|.||| ||..| |. . .|.|. ||| . . ||||.|..|| ..| |.|.
fkeeyeslfeg....wdaakkdenreknrsgdilaydrsrvflitidgdpssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasivmlte
LKEGDKIKCGKYWPNkpgDSVKFGYIRVELVSLEACTGGIKRTMTMLK----GDDCRTVTQFHFTEWPDKGVPKHTSALLKFIKEVKADHGQYTHPLIIH
|.| ..|| ||||. |. ..| |.||||. |. . ..|.... | .. |.| ||.|. ||| .||.. .|||....||. . . ....|
lvevgrvkClkyWPe...dtevygdikvelvetellaelvvrifrveklargqeeirevrqfqflgWpdhdvPvsatgllklvrrvkksqeeeaGrivvh
CSAGVGRTGVVISIDSVVAHAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLEDLLWRNTLIPVIHFTDHLQDLHSSGDGHGRSKMTKEFQT
|||| ||||. | ||.|. ... ..||||| | ..|.... ||.|.||| ||| ..|| | .| ||| .| . |.. .||||
CsaGaGrtGtfiaidivldmieregvvdvfnavktlrsrkvnmveteeqykfiydvileaclcgetaipvsefkalylesirldpqtnssqlkeefqt
|
|||||||||
subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 593-870 | 4.2e-72 | 238.1 | In-house | 36-312 (319) | alignment | ||
Range on Protein: 593-870
Range on HMM: 36-312/319.0
FSEEFHDLP--GPNIYPQTVAQEEINFKKNRYKNILPYDSVRVKLEVINDNPHSDYFNASYIPSFDNDKAYIASQGPNKASMDDFWRMVWQENVTTIAMV
. ||. .. |.| || | . | |||. |||..| .|||| .. ||| |||.. . . . |||.||| . ...|||||.|. |..|| ..
levefrracklgvnladqtfanldqnkdknriinilafdknvvklerliGeefsdyinasfvtGyqrkdkyiaaqGPldntladfWrmiweyncstivll
TklkegdKIKCGKYWPNKPGDSVKFGYIRVELVSleACTGGIKRTMTMLK---GDDCRTVTQFHFTEWPDKGVPKHTSALLKFIKEVKADHGQ--YTHPL
| | || .|||.| . . ..|..| . . | . . . | | .||||| |||.|||...| |....| |. . . ...
t......kdkcsqywplkivikeerfkvkvdsve..etaeyvvrdielsedgkekdirkitqfhflGwpdvGvpdypsdlmrlvkkvrhltskenhrani
IIHCSAGVGRTGVVISIDSVVAHAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLEDLLWRNTLIPVIHFTDHLQDLHS
..||||||||||| | .| .. | ..|||.||| ..||.|. .|| || ||| |.||. |. .. . . | .|..| .
vvhcsaGvGrtGvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleehlfghsdvampdfpayleelsn
|
|||||||||
subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 593-846 | 1.3e-44 | 147.0 | In-house | 13-266 (281) | alignment | ||
Range on Protein: 593-846
Range on HMM: 13-266/281.0
FSEEFHDLPG-PNIYPQTVAQEEINFKKNRYKNILPYDSVRVKLEV-INDNPHSDYFNASYIPSFDNDKAYIASQGPNKASMDDFWRMVWQENVTTIAMV
| .|| .||| | || .. .| ||||| || | ||.|.| . .. .|| | || | . || .|||.| . |||||.|||| |.| |.
fkqefsnlpgdppsdlctvfnqpvnnkknrylnipcldisrvqlkvkmpnknstdyihanyirspflkrgyiltqgpkketradfwrmiwqenttaivml
TKLKEGDKIKCGKYWPNKPGDSVKFGYIRVELVSLEACTGGIKRTMTMLKGDDCRTVTQFHFTEWPDKGVPKHTSALLKFIKEVKADhgqyTHPLIIHCS
.. | .. || .|.| . ..| . |. . . . . | .|.. . |||| ||. . .|| .....| . | .||||
cqfletnrekcaeyfprnahcclqfdklsvsyedstvnkslvttrlnlsyegetrlithwlwkewpdwqvpessevmlkilrkirar....stppvihcs
AGVGRTGVVISIDSVVAHAKT-TRMVDVFNFVTNIRQ-KRPYMVQTQEQYAFIYGAVL
|||||.| ..... . .. . |. . |. .| | ||| .|| .|. .|
agvgrsgtlmaveialqsihshftlpdikqivshlrvtgraasvqtlqqymliwkvll
|
|||||||||
0046845 | (Phosphotyrosine protein) phosphatases II | 594-855 | 4.3e-88 | 290.6 | In-house | 3-280 (284) | alignment | ||
Range on Protein: 594-855
Range on HMM: 3-280/284.0
SEEFHDLPGPNIY---PQTVAQEEINFKKNRYKNILPYDSVRVKLEVINDN-PHSDYFNASYIPSF-----DNDKAYIASQGPNKASMDDFWRMVWQENV
|||. |. ... . .||. . |..|||||.|||||. |||| ..... ..|||.||||.. . .. |..|| ||| . ...|||||||..||
eeefeellsltvklllslsvallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqnv
TTIAMVTKLKEGDKIKCGKYWPNKpGDSVKFGYIRVELVSLEACTGGIKRTMTMLK---GDDCRTVTQFHFTEWPDKGVPKHTSALLKFIKEVKADHG--
..| |.|.| | ...|| .|||.. |.....| ..|.|.| | . . ..||... . .. ||||.||.|.||| ||| ... ||.|...|. .
rvIVmltelvengrekcaqYwple.gevltygdftvtllseevkddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrellenl
QYTHPLIIHCSAGVGRTGVVISIDSVVAHAKTTR---MVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLEDLLWRNTL
. .| ..||||||||||..| .| . . .... .|||.. | .|..||.|||| ||| |.| |.|| |....||
pgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleylklkltl
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 594-777 | 8.7e-27 | 88.6 | In-house | 8-193 (319) | alignment | ||
Range on Protein: 594-777
Range on HMM: 8-193/319.0
SEEFHDLPgpNIYPQTVAQEEINFKKNRYKNILPYDSVRVKLEVINDNPHSDYFNASYIPSFDND-KAYIASQGPNKASMDDFWRMVWQENVTTIAMVTK
|||.||| .. .. . .|.|. |..| || |. | |.... |..|||. .|. |||.| . . | ||||.||. . .| .|.
aeefrdlP..qliaradevPvtskdksrvinvvPlPetrvvlqrigdddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltd
LKEGDKIKCGKYWPNKPGD--SVKFGYIRVELVSLEACTGGIKRTMTM--LKGDDCRTVTQFHFtEWPDKGVPKHTSALLKFIKEVKAD
| | .| .|.| | . .| |.| | |. . |. . .... .| .| . . .|.. .|| . .||. . ||..
lselGikvcaeylPtketldntslyGdilvtlkgrevkdryaistlllkrvdkeesrelthywy.kwleaevPaeeaaliamllevrss
|
|||||||||
subfamily_PTPN13_pd | Subfamily PTPN13 | 595-849 | 1e-66 | 220.0 | In-house | 15-269 (273) | alignment | ||
Range on Protein: 595-849
Range on HMM: 15-269/273.0
EEFHDLPGPNIY-PQTVAQEEINFKKNRYKNILPYDSVRVKLEVINDnphsdYFNASYIP--SFDNDKAYIASQGPNKASMDDFWRMVWQENVTTIAMVT
|||..| .|.... | .||||.|.|||| ||||. | |||.| .. |||.||| ...|||.|||. ... |||||
eefkelrelkpldtcevgkkkenkdknryrnvlPydetrvklgdegg.....yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamvt
KLKEGDKIKCGKYWPNKPGDSVKFGY-IRVELVSLEACTGGIKRTMTML--KGDDCRTVTQFHFTEWPDKGVPKHTSALLKFIKEVKADHGqYTHPLIIH
. ||..|.|| .|||.. ....| ..|||. .. | |.... . . | |....|..||| |||... ||.|..||. . . |...|
lekekgkvkchrywPesknkklkvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaellqfvaevrrlqt.dagPivvh
CSAGVGRTGVVISIDSVVAHAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLEDL
||||.||.|..|.|| |. . . .|| . | ..|..| .|||..|| |.| |.|| |
csaGiGrsGtlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykailevl
|
|||||||||
subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 595-850 | 1.4e-43 | 144.1 | In-house | 20-278 (307) | alignment | ||
Range on Protein: 595-850
Range on HMM: 20-278/307.0
EEFHDLPGPNIYPQTVAQEEINFKKNRYKNILPYDSVRVKLEVinDNPHSDYFNASYIPSFDNDKAYIASQGPNKASMDDFWRMVWQENVTTIAMVTKLK
.||. | . || . | .||||... | |. ... | ||| | |. . | .|..||| .... .|| |. ||.| .. |. |.
defrvlakktpegvtveafsantdknryqdvkcqdkgrivvkf..dglasdyihanylgiaikpkkficaqgplentqysfwamaiqekvesvimlckvi
EGDKIKCGKYWPNKPGDSVKFGYI----RVELVSLEAC---TGGIKR-TMTMLKGDDCRTVTQFHFTEWPDKGVPKHTSALLKFIKEVKADhgqyTHPLI
| |||| .||| . |. || |. . . |. |. . ....||.... ...|||.|||. . . ... |. | | |..
elakikceqywpleegqklvfgeapntisvanlgakklapdedlinvttlkvdwaqksrtiqhlqwenwpdrgvpqinltainlleavryd....tnpvv
IHCSAGVGRTGVVISIDSVVAHA-KTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLEDLL
.||||||||.| ...| | . |. ..| ..|..|.| .||. || ... .|| .|
vhcsaGvGrsGtivaislvqdkmiaGinckdmkklveelrsqrhyaiqteaqylylhrvlleyfl
|
|||||||||
subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 602-870 | 6e-71 | 234.2 | In-house | 11-276 (284) | alignment | ||
Range on Protein: 602-870
Range on HMM: 11-276/284.0
GPNIYPQTVAQEEINFKKNRYKNILPYDSVRVKLEVINDNPHSDYFNASYIPSFDNDKAYIASQGPNKASMDDFWRMVWQENVTTIAMVTklkegdKIKC
|.| || | . | |||. .||..| .|||| . . ||| |||.| . . . |||.||| . ...|||||.|. |..|| ..| | ||
gvngtdqtfanldqnkdknrighilafdknvvklerliGeefsdyinasfitGyqrkdkyiatqGPldntladfWrmiweyncstivllt......kdkc
GKYWPNKPGDSVKFGYIRVELVSleACTGGIKRTMTMLK---GDDCRTVTQFHFTEWPDKGVPKHTSALLKFIKEVKADHGQ--YTHPLIIHCSAGVGRT
.|||.| . . ..|..|. . . | . . . | |...|||| |||.|||...| |....| |. . . .....|||||||||
sqywplkivikeerfkvkvdsve..eseeyvvrdielsedgkekdirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrt
GVVISIDSVVAHAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLEDLLWRNTLIPVIHFTDHLQDLHS
|| | .| .. | ..|||.||| ..||.|. .|| || ||| |.||. |. .. . . | .|..| .
gvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleehlfghsdvalpdfpayleelsn
|
|||||||||
subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 603-852 | 6.6e-36 | 118.8 | In-house | 29-274 (288) | alignment | ||
Range on Protein: 603-852
Range on HMM: 29-274/288.0
PNIYPQTVAQEEI-NFKKNRYKNILPYDSVRVKLEvinDNPHSdYFNASYIPSFDNDKAYIASQGPNKASMDDFWRMVWQENVTTIAMVTKLKEGDKIKC
|| .. .... | | ..||.|. | ||||. |.|. | .| ..| ... | .| | .. .. .|.|. ...| | |...| | | |
pneasidiidsfianptrdryenlprcditrvkls...ddpdf.yiaanvvssakykrrlicaqaPlngtieelWkmllesdveyivmlcellekGkeks
GKYWPNKPGDSVKFGYIrVELVSLEActGGIKRTMTM--L----KGDDCRTVTQFHFTEWPDKGVPKHTSALLKFIKEVkadhGQYTHPLIIHCSAGVGR
.|.| | |.....| . | . .|...... | .|.. | . |. ||.|.|||. . |.... . ....|...|.||||||
aeyfPsklGekarigrl.ctvvkkkr..adidklvkvsllriskegeekvivkilhlleWdddgvPenylsplrllevl....kslqkPivvhssaGvGr
TGVVISIDSVVAHAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLEDLLWR
|| .| | .. .. . . . ..... |..| .||. || ... |||.|| .
tgtlililialeslrlddflgirsllaklreerfkaiqtemqylyvhrcvleelllk
|
|||||||||
subfamily_PTPN12_pd | Subfamily PTPN12 | 604-847 | 3.7e-83 | 273.7 | In-house | 28-275 (290) | alignment | ||
Range on Protein: 604-847
Range on HMM: 28-275/290.0
NIYPQTVAQEEINFKKNRYKNILPYDSVRVKLEVINDNPHSDYFNASYIPSFDNDKAYIASQGPNKASMDDFWRMVWQENVTTIAMVTKLKEGDKIKCGK
..|.......| | ||||||.||||| ||.|. |.....||| ||..| .....|||.||| . .||||||.|. ||. . |. .. | .|.|| .
kvysteagekeenvkknrykDilPydksrvelskieeeegsdYinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCer
YWPNKPGDSVKFGYIRVELVSLEACT-GGIKRTMTMLKGDDCRTVTQFHFTEWPDKGVPKHTSALLKFIKEVKADHGQYTHPLIIHCSAGVGRTGVVISI
|||.. .....|| ..|.| . .|.. . . ||... . ...|.|.|||.|.|||.|||. .. ||..|..|. . . .||..||||||||||..|.|
YWpeegeeelefgefevtleeekavdddflirtLkveaqkesrkvyqfhYtaWPDhgvPssaksllelielvrelqesedaPlvvhCsaGvGrtGtiiai
DSVVAHAKTTRM---VDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLE
| | |. .. .|||. |...|..|. .|||.||| ..| ||.|
dyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavae
|
|||||||||
subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 604-850 | 2.2e-24 | 80.7 | In-house | 30-277 (312) | alignment | ||
Range on Protein: 604-850
Range on HMM: 30-277/312.0
NIYPQTVAQEEINFKK-NRYKNILPYDSVRVKLEviNDNphSDYFNASYIPSFDNDKAYIASQGPNKASMDDFWRMVWQENVTTIAMVTKLKEGDKIKCG
||.... ..|| ||| || .| | | |. | | .. . . ....||| . . ||... |.| ... . | ||
nivsdsectaflkfkdlnrypniqcwdrgrftla..gde..nfyihanfvkictkperfvctqgplentcthfwqlalslgstsiillcgfvedgsekca
KYWpnkpGDSVKFGYIRVELVSLEACT----GGI---KRTMTMLK------GDDCrTVTQFHFTEWPDKGVPKHTSALLKFIKEVKADHgqytHPLIIHC
|| | | | . | | || || | | .|| |.. . .. .. |||.|.| . |... || |. .|.| ||
kyi....sdivgfvdledhrvyteycteieiggkskdkithrvlkvvvkatgqes.klnhyqwaswpdhgmpdscdtalrllsavkkdk....kpviahc
SAGVGRTGVVISIDSVVAHAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLEDLL
|||||||| .. |.|..| . | .| . .|. | |.. || . .||| |
sagvgrtgtlaliesmiaalrhprkqnvkdsfvllrkdrarsvrvfpqyvyalrcvlefly
|
|||||||||
subfamily_PTPN1_pd | Subfamily PTPN1 | 605-848 | 1.4e-55 | 183.1 | In-house | 21-270 (290) | alignment | ||
Range on Protein: 605-848
Range on HMM: 21-270/290.0
IYPQTVAQEEINFKKNRYKNILPYDSVRVKLEVINDnphsDYFNASYIPSFDNDKAYIASQGPNKASMDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKY
.|...|... | ..|||... ||| |.||| . || ||| . . .. || .||| .| ||.|||... .. |. |. | ..||| .|
dfptreaklpenrnlnryrdvspydhsrikleradn....dyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvvekeqikcaqy
WPNKPG-DSVKFG--YIRVELVSLEACTGGIKRTMTM--LKGDDCRTVTQFHFTEWPDKGVPKHTSALLKFIKEVKADH--GQYTHPLIIHCSAGVGRTG
||.. ..... ..|.|.| | . |.. . || ...|....||.| ||| |||. .|.|||. .|. . | .||||||.||.|
wPqgeeekellledtklkvkliseerksyytvrllelenlktqetreilhfhyttwpdfgvpespaaflkflfkvresGslssdvGpavihcsaGiGrsG
VVISIDSVVAHAKTTRM---VDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLED
.. .|..... . . ||. . . ..|. | ..||..| | | |.||
tfclvdtclvliekkddlssvdikkvllelrkyrlGliqtadqlrfsylaileG
|
|||||||||
subfamily_Cele-PTP-12_pd | Subfamily Cele-PTP-12 | 605-700 | 1.3e-07 | 25.4 | In-house | 23-117 (332) | alignment | ||
Range on Protein: 605-700
Range on HMM: 23-117/332.0
IYPQTVAQEEINFKKNRYKNILPYDSVRVKLevINDNPHSDYFNASYIPSFDNDKAYIASQGPNKA-SMDDFWRMVWQENVTTIAMVTKLKEGDKIK
||.| . |. || . .| ||.| .. . |..|||.. . . ||| .| | . . ||||| . . . | .. . | .| |
typntydkflnnmdmnriphlycfdhsrvel..apqdgkddfynaswvdgyskksayifaqapfndhteyvfwrmvserkpsmilvfgdidekqkrk
|
|||||||||
subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 606-655 | 5.9e-06 | 20.1 | In-house | 29-77 (244) | alignment | ||
Range on Protein: 606-655
Range on HMM: 29-77/244.0
YPQTVAQEEINFKKNRYKNILPYDSVRVKLEVINdNPHSDYFNASYIPSF
. || | | |||| ||||.| .|| | . . ||| ||.|| .
flqtnavlsanatknryinilpfdetrvilsssk.kegsdyinanyiqgs
|
|||||||||
DSPc_SM00195 | 607-847 | 1e-83 | 276.0 | In-house | 17-260 (263) | alignment | |||
Range on Protein: 607-847
Range on HMM: 17-260/263.0
PQTVAQEEINFKKNRYKNILPYDSVRVKLEVINDNPHSDYFNASYIPSFDNDKAYIASQGPNKASMDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWP
. | |... | .|||||||||||. ||||. ......||| ||.|| ...|.||| ||| . ..|||||||.|.|..|.|.|. .| .|.|| .|||
etteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengkekcdrywp
NKPGDSVKFGYIRVELVSLEACT-GGIKRTMTMLKGD--DCRTVTQFHFTEWPDKGVPKHTSALLKFIKEVKADHGQYTHPLIIHCSAGVGRTGVVISID
.. |.. .||.|.|.||. | . |.||... | . . |.|||.....|||.|||..|. .|.....|| .. . ..|...||||||||||....||
eesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivVhCsaGvgRtgtfvtid
SVVAHAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLE
... . ... .||.|. |...|..|| ||||.|||.||| |.||
iilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaile
|
|||||||||
PTPc_SM00194 | 607-847 | 1e-83 | 276.0 | In-house | 17-260 (263) | alignment | |||
Range on Protein: 607-847
Range on HMM: 17-260/263.0
PQTVAQEEINFKKNRYKNILPYDSVRVKLEVINDNPHSDYFNASYIPSFDNDKAYIASQGPNKASMDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWP
. | |... | .|||||||||||. ||||. ......||| ||.|| ...|.||| ||| . ..|||||||.|.|..|.|.|. .| .|.|| .|||
etteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengkekcdrywp
NKPGDSVKFGYIRVELVSLEACT-GGIKRTMTMLKGD--DCRTVTQFHFTEWPDKGVPKHTSALLKFIKEVKADHGQYTHPLIIHCSAGVGRTGVVISID
.. |.. .||.|.|.||. | . |.||... | . . |.|||.....|||.|||..|. .|.....|| .. . ..|...||||||||||....||
eesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivVhCsaGvgRtgtfvtid
SVVAHAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLE
... . ... .||.|. |...|..|| ||||.|||.||| |.||
iilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaile
|
|||||||||
0040439 | (Phosphotyrosine protein) phosphatases II | 607-847 | 5.4e-75 | 247.5 | In-house | 2-244 (249) | alignment | ||
Range on Protein: 607-847
Range on HMM: 2-244/249.0
PQTVAQEEINFKKNRYKNILPYDSVRVKLEVINDNPHSDYFNASYIPSFDNDKAYIASQGPNKASMDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWP
. .||. . | .||||..|||||. ||||..... ..||| |||||. .. ...|| ||| . ...|||||.|....|.| |.|.|.| ...|| .|||
eysvallpenkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywp
NkpGDSVKFGYIRVELVSLEACTGGIKRTMTML--KGDDCRTVTQFHFTEWPDKGVPKHTSALLKFIKEVKADHGQ--YTHPLIIHCSAGVGRTGVVISI
. |.|...| ..|.|.| | . . . ||... . .. |||.....| ||| |||.... ||.||..|. . . .|...||||||||||..| .
l..ggsleygdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaa
DSVVAHAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLE
. .. . .... ||... | .|..||..||..||| |.| |.||
ylmleqlekelgvdleeavkllrsqRpgavqnpeqyrflyealle
|
|||||||||
subfamily_Sponge-PTP-2_pd | Subfamily Sponge-PTP-2 | 607-764 | 4.5e-07 | 22.9 | In-house | 18-158 (169) | alignment | ||
Range on Protein: 607-764
Range on HMM: 18-158/169.0
PQTVAQEEINFKKNRYKNILPYDSVRVKLEVINDNPHSDYFNAsyipsfdndkayiasqgpnkasmddfwRMVWQENVTTIAMVtklkeGDKIKCGKYWP
. .|. .| ||| | .||||. . .. ||| || ||.|. | . | .. || .||
nnfmaeltcnetknrpagplapshtrvklqrvmedlgsdyina...........................rmiwetnasvivvl.....gdtddknnfwp
NKPGD----SVKFG-------YIRVELVSLEAC--TGGIKRTMTMLKGDDCRT--VTQFHFTEWPDKGVPKHT
.| .| .| |.| . | . | .. .| . . || | .. .|.. ||..|||.
ekedyqlhpavilgewytdslyvrtdkvhantsgveglfevsmvihsydddvteklsllhystwpqngvpqsp
|
|||||||||
subfamily_PTPRN_pd | Subfamily PTPRN | 608-848 | 8.4e-59 | 193.7 | In-house | 48-291 (297) | alignment | ||
Range on Protein: 608-848
Range on HMM: 48-291/297.0
QTVAQEEINFKKNRYKNILPYDSVRVKLEVINDNPHSDYFNASYIPSFDN-DKAYIASQGPNKASMDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWP
..||..| | ||||.|..|||| ||||. ... .||| ||| | | ||||.||| ... |||.|||.. |. | ..|.|.| . .| .|||
kevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplastvadfwqmvweqGvvvivnltrleeegvkqckrywp
NKpGDSVkFGYIRVELVSLEA-CTGGIKRTM--TMLKGDDCRTVTQFHFTEWPDKGVPKHTSALLKFIKEVKADHGQYTHPLIIHCSAGVGRTGVVISID
.. | .| .. |.||| | . |.. |. .. |||||||| ||..||| . .||.| . | . . |...|||.|.||||| | ||
de.Gsev.yhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrGrscpivvhcsdGaGrtGvyilid
SVVAH-AKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLED
|... .| . .|. . .|..|| .|.|..|. |...|| |.
lvlnrllkGvkeidiaatlehlrdqrpglvktkdqfefaltavaee
|
|||||||||
0049772 | (Phosphotyrosine protein) phosphatases II | 608-851 | 1.5e-37 | 125.4 | In-house | 38-282 (314) | alignment | ||
Range on Protein: 608-851
Range on HMM: 38-282/314.0
QTVAQEEINFKKNRYKNILPYDsVRVKLEVINDNPhSDYFNASYIPSFdndKAYIASQGPNKASMDDF----------WRMV--WQENVTTIAM------
.||. . | .||||..|||.| ||.| . . |||.||||. .| ...||.|||.. ..|| |||| .. || .| |
ilvadlflnrdknryldilpad.nrvilpglpvsg.sdyinasyvdgf...lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivmsrdevl
---------------VTKLKEGDkikcgkywpNKPgDSVKFGYIRvelvsleactggikrtM-TMLKGDDCRTVTQFHFTEWPDKGVP--KHTSALLKFI
..| .. | | . . ... . . . |.. ... . .|| ..| .. ..|.||
adelsrLdaAlgKtpllildgng.........nep.taadlellk................eelydpelferlgikylripvpDgsaplledfdeflefi
KEVkadhgQYTHPLIIHCSAGVGRTG--VVISIdsVVAHAkttRMvDVFNFVTNIRQKRP-----YMVQTQEQYAFIYGAVLEDLLW
.|. . .|...||.||.|||| ||. . .. . .. .. . .|.||| .....||| ||. |.|| | .
eea.....dkggpvlvHCkaGkgRtgtfvvaay..lmkll...gv.sleealedvrlkRpinpnpgfieqleqyefilealleylkf
|
|||||||||
subfamily_egg_pd | Subfamily egg | 608-846 | 4.1e-30 | 99.5 | In-house | 32-267 (307) | alignment | ||
Range on Protein: 608-846
Range on HMM: 32-267/307.0
QTVAQEEINFKKNRYKNILPYDSVRVKLEVINDNPHSDYFNASYIPSFDNDKAYIASQGPNKASMDDFWRMVWQENVTTIAMVTKLKEGDkiKCGKYWPN
| | .. | .| | | . || |||||. . |. | .. .| .| | | ..|||||||.||.| | |.| || . .| |||.
lttaasdnnlekarskrvhckdssrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvddfwrmvfqeevqyivmltsrkese..rceyywpk
KPGDSVKF--GYIRVELVSLEACTGGIKRtMTMLK--GDDcrtVTQFHFTEWpdKGVPKHTSALLKFIKeVKADHGQYTHPLIIHCSAGVGRTGVVISID
. ||... | .|.| . .. . . | .| || | | . . | .| ...| . .. | . ..| .... || .......|.
aesdslvtvpGslrienlkvdskadplfr.vtklklvGgd...deerflehw..qgdvnnssdvysplr.vlrklrnlskpvvvqdilGvskaatlvaie
SVVAHAK--TTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVL
. . . | . | .|..|.. |.. .| |.| ||
iallsllrGpitkslvlravvflrlrrrlsvesvllylfvyrlvl
|
|||||||||
subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 608-692 | 7.7e-09 | 29.5 | In-house | 29-118 (347) | alignment | ||
Range on Protein: 608-692
Range on HMM: 29-118/347.0
QTVAQEEINFKKNRYKNILPYDSVRVKLEV-----INDNPHSDYFNASYIpSFDN-DKAYIASQGPNKASMDDFWRMVWQENVTTIAMVTK
|... | . .||| |. |. || | . .. | |||.| ||| .| || .| | .. |||.|| .|| . . .
ftsvewekslsknrskdvklidatrvvlspeksknsraddvetyinashi.kfdnaskeyiltqyplpdtvrdfwkmvsvtkvtqvvtife
|
|||||||||
subfamily_Sponge-PTP2_pd | Subfamily Sponge-PTP2 | 608-764 | 7.9e-07 | 22.0 | In-house | 18-157 (169) | alignment | ||
Range on Protein: 608-764
Range on HMM: 18-157/169.0
QTVAQEEINFKKNRYKNILPYDSVRVKLEVINDNPHSDYFNAsyipsfdndkayiasqgpnkasmddfwRMVWQENVTTIAMVtklkeGDKIKCGKYWPN
. .|. .| ||| | .||||. . .. ||| || ||.|. | . | .. || .||.
nfmaeltcnetknrpagplapshtrvklqrvmedlgsdyina...........................rmiwetnasvivvl.....Gdtddknnfwpe
KPGDSVK----FG-------YIRVELVSLEacTGGIK--RTMTMLKGDDCRTVTQ----FHFTEWPDKGVPKHT
| .. .| |.| . | . | |.. ....... ..||. .|.. ||..|||.
kedyqlhpavilGewytdslyvrtdkvhpn..tsgveglfevslvihsydddvteqlsllhystwpqngvpqsp
|
|||||||||
subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 609-849 | 8e-80 | 262.6 | In-house | 2-242 (250) | alignment | ||
Range on Protein: 609-849
Range on HMM: 2-242/250.0
TVAQEEINFKKNRYKNILPYDSVRVKLEVINDNPHSDYFNASYIPSFDNDKAYIASQGPNKASMDDFWRMVWQENVTTIAMVTKLKEGDKIkCGKYWPNK
.||.. | .|||| .|...|| || || . . .||| |||.. ..|. ||.||.||| .|.. ||||||..|...|| |.|.||| .| . .||| .
svakkpqnkeknryadiialdssrvvLekekgdkesdyinasflhgyderkafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqywPve
pgDSVKFGYIRVELVSLEACTGGIKRTMTMLKGD--DCRTVTQFHFTEWPDKGVPKHTSALLKFIKEVKADHGQ-YTHPLIIHCSAGVGRTGVVISIDSV
. |.| ..|.| | | . .||.. . | | |.| |.||. |||||||... | |...|.|.| . | . |.|..|||||||.| | ||.|
..kaekyGdvtvsllskeefadytkrklklskakkaderivrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidav
VAHAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLEDL
. ..|. ..||||... .|..|| .|...||| |.| ..|. |
lerlkkekvvdvfkvikvlrkdrphavesleqyvfvyeiilkal
|
|||||||||
0037934 | (Phosphotyrosine protein) phosphatases II | 609-847 | 8.4e-67 | 220.5 | In-house | 3-240 (243) | alignment | ||
Range on Protein: 609-847
Range on HMM: 3-240/243.0
TVAQEEINFKKNRYKNILPYDSVRVKLevinDNphSDYFNASYIPSFDNdkaYIASQGPNKASMDD----FWRMVWQENVTTIAMVTKLKEGDKIKCGKY
..|. . | .||||..||||| |||| .. |||.||..|. ... .||.||| . . .| ||||.|....|.| |.|.|.| ...|| .|
siallpenlsknrysdilpydhsrvkl....eg..sdyinanliyvtpr...liatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqy
WPnkpgDSVKFGYIRVELVSLEACTGGIKRTMTMLK---GDDCRTVTQFHFTEWPDKGVPKHTSALLKFIKEVKAD----------HGQytHPLIIHCSA
|| ..| .| ..|.|.| | . . . ||... .| .|.|...|.. ||| ||| ... ||.|..||.. ... .|...||||
wp....gevtygdftvtllseehlddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsg..gpvlVHCsa
GVGRTGVVISIDSVVAHAkttRmVDVFNFVTNIRQKRPY-MVQTQEQYAFIYGAVLE
||||||..| .. . . . ||... | .|..||. .|||..|| |.| |.||
GvgRtGtliaaylmllll...g.vdleeavkllreqRpgkavqtpsqyrflyealle
|
|||||||||
subfamily_PTPN3_pd | Subfamily PTPN3 | 609-847 | 3.3e-66 | 218.1 | In-house | 34-273 (280) | alignment | ||
Range on Protein: 609-847
Range on HMM: 34-273/280.0
TVAQEEINFKKNRYKNILPYDSVRVKLEvinDNPHsDYFNASY----IPSFDNDKAYIASQGPNKASMDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKY
..|. | .||||..|||||. ||||. ... || ||.| ||| . . |||.||| . .. |||.|||......| |.| | | ..|| .|
saarkpenlsknryrdilpydatrvklk...eset.dyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqksslivmlttlverGrvkChqy
WPNkPGDSVKFGYIRVELVSLEACTGGIKRTMTMLKGD--DCRTVTQFHFTEWPDKGVPKHTSALLKFIKEVKADHGQYTHPLIIHCSAGVGRTGVVISI
||. ..|....| ..|.. . .. . . | ... . . . |...|. ...|||.|||.... .|.|...|.. . ..|...|||||.|||||.| .
WPe.tedeleygefsvkcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklrsgkeePvvvhCsaGigrtGvlill
DSVVAHAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLE
. .| ... | . . | ..|..| .|||..|| |. |.|.
etalalieaaepvypldivrtmrdqramlvqtasqykfvCeailk
|
|||||||||
subfamily_PTPN14_pd | Subfamily PTPN14 | 609-847 | 1.5e-58 | 193.1 | In-house | 42-294 (300) | alignment | ||
Range on Protein: 609-847
Range on HMM: 42-294/300.0
TVAQEEINFKKNRYKNILPYDSVRVKLEVINDNpHSDYFNASYIPS--FDNDKAYIASQGPNKASMDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWP
..|. . | .|||.|..|||. .||.| ..| ...| ||| | ... ||..||| . . |||.|||...|. |.|.|. .|. | |. ||.|
staklpenaeknrfkdvlPyednrvelsptken.stgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivmlteeeedgkeksfkyfP
NK--PGDSVKFGYIRVE--LVSLEACTGGIKRTMTMLKGDDCRTVTQFHFTEWPDKGVPKHTSALLKFIKEVKA--DHGQY-------THPLIIHCSAGV
.. ..|.|| .| ... .. .. .. | . ||| . .|.|||.|||. . |....||.. . . |...||||||
kleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseveskeskPPvlvhCsaGv
GRTGVVISIDSVVAHAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLE
|||||.| | ..| .. . .|. . .. .|..| ..||| || |.| ....
GrtGvlilsdlliatlehneeidikkvlarLreqrmllvqtlaqYkfvYkvlik
|
|||||||||
subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 609-846 | 1e-41 | 137.5 | In-house | 49-280 (290) | alignment | ||
Range on Protein: 609-846
Range on HMM: 49-280/290.0
TVAQEEINFKKNRYKNILPYDSVRVkleVINDNPHSDYFNASYIPSFdnDKAYIASQGPNKASMDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNK
. ... .|||||||.. | || ...| . || | |. . .| .||. |... |.|||| ||.|..| |. .| | | || .|.|.|
kifdkntefkknrykdvvcndktrv...ilkdGydGdyvhanyvkGl..kamfiltqGalkdtvidiwrmvlqekvaaivmlceliedGkakceqyypek
PGDSVKFGYIRVELVSL-EACTGGIKRTMTMLKGDDCRT--VTQFHFTEWPDKGVPKHTSALLKFIKEVKADHGqythPLIIHCSAGVGRTGVVISIDSV
|. . || | | . . ||.|... . |. . . .. |||| |.. | |||. .. .. | |...|||||.|||| ..|.
eGevltfGeitvlcseeddkdaniikktlsvrdkdsGkehklkhlkikswpdksvalstlallrtlrilrkasG....pvvvhcsaGiGrtGtfvaievg
VAHAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVL
. . .|. . | .|. | || . || . ..|
lqilldGkeldlldlvralrnsrlnsvqvdiqylalveill
|
|||||||||
0042113 | (Phosphotyrosine protein) phosphatases II | 610-847 | 1.7e-72 | 239.1 | In-house | 3-241 (245) | alignment | ||
Range on Protein: 610-847
Range on HMM: 3-241/245.0
VAQEEINFKKNRYKNILPYDSVRVKLEVINDNPHSDYFNASYIPSFDNDKAYIASQGPNKASMDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNkp
||. . | .||||..|||||. |||| ... ...||| ||||.. .. . .||.||| . . .|||||.|....||| |.|.. | ...|| .|||.
vallpenkdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywpl..
GDSVKFGYIRVELVSLEACTGGIKRTMTML--KGDDCRTVTQFHFTEWPDKGVPKHTSALLKFIKEVKADHG-QYTHPLIIHCSAGVGRTGVVISIDSVV
|.|...| ..|.|.| | . . . ||... . | |.|...|.. ||| ||| ... ||.|...|. .|...||||||||||..| .. ..
gesltygdftvtllseehlddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylml
AHAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLE
...... |.... | .|..|| .|||..|| |.| |.||
eqlekelgvsleeavkelrsqRpgavqtpsqyrflyealle
|
|||||||||
subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 610-847 | 1.9e-69 | 228.7 | In-house | 14-262 (270) | alignment | ||
Range on Protein: 610-847
Range on HMM: 14-262/270.0
VAQEEINFKKNRYKNILPYDSVRVKLEVINDNPHSDYFNASYIPSFD-NDKAYIASQGPNKASMDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNK
. . . | |||..||| ||.|| ....... |.|| |.. || ..|.|||..|| .... .||||.|.|.||.|.|.|.|.| . || .|||..
lpeaargkklnRyadiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpae
PGD--SVKFGYIRVELVSLEACTGGIKRTMTMLKGDDCRTVTQFHFTEWPDKGVPKHTS------ALLKFIKEVKADHGQYT--HPLIIHCSAGVGRTGV
|.. ....| |.| .| | .| |.. ... . . | .. |....|||.|||... ||| ...|.. . . .||..||||||||||.
pkekvkledgkikvlalseekeegyiltrlrleekgeerrlvHfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcsaGvgRtGt
VISIDSVVAHAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLE
.| .| .| ..|. ||| . ....|..|. .||. |||.|.| ||.|
lialDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyeflykavve
|
|||||||||
subfamily_PTPN23_pd | Subfamily PTPN23 | 610-848 | 1.9e-63 | 209.0 | In-house | 37-279 (288) | alignment | ||
Range on Protein: 610-848
Range on HMM: 37-279/288.0
VAQEEINFKKNRYKNILPYDSVRVKLEvindNPHSDYFNASYIPSFDND-KAYIASQGPNKASMDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNK
.| ... .|||...|||||. ||||. . . || |||.. . .||.|.| . .. |||.||... . .| |... .| .| |. .|||..
iaiaklyseknrsrdilPyDhnRvklr....gskDDYinAsfvkdlspgcPdfiatqaPlqstlnDFWlmvyeqkssviVmllskeelgkpkvdrYwPed
PGDSVKFGYIRVELVSLEACTGGIKRTM--TMLKGDDCRTVTQFHFTEWPDKGVPKHTSALLKFIKEVKA----DHGQYTHPLIIHCSAGVGRTGVVISI
|..|||| ..| | | . ..|.. ..|. | ..|. ..|.||. |||. . ||.|..||.. . . ||..|||||||||||. .
kgetvkfgdlsvtlksvretethvervlkletldadavksvshlqltsWpelGvPasPetllqfldevesayeavqrksktPlvvhCsaGvgRtgvfalv
DSVVAHA-KTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLED
..|. | ..|. . | .|..| .|||..||. | | ||||
yaavrelekgnglldiiqvvsrlreqRrfmvqekeqlkfsyeavlea
|
|||||||||
subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 610-846 | 3.9e-52 | 171.8 | In-house | 32-274 (287) | alignment | ||
Range on Protein: 610-846
Range on HMM: 32-274/287.0
VAQEEINFKKNRYKNILPYDSVRVKLeVINDNPHSDYFNASYIPSFDNDKAYIASQGPNKASMDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKp
|.| . ||||| ..||.| || | . . . ||| || |..|. .|.|.||.||| |.. ||||.|...........|. | . || ||||..
aaeelaavkknryadvlPiddtrvll.saegelGsdyinanyvasytddeafiaaqgPiaatvrdfwravletrsasvitmtreveearlkcykywPer.
GDSVKFGYIRVELVSLEACTG-GIKRTMTM--LKGDDCRTVTQFHFTEWPDKGVPKHTSALLKFIKEV-----KADHGQYTHPLIIHCSAGVGRTGVVIS
.. | | |.. . |.. . |.. ..| | |... .||||... . .|..|. .| | .. . ||..|...|.||.|....
evPmrvGGysvvlldydikePeygvralrlidletrearvvkqldllswPdkvlaPtavglirfvldvkqhielardasevGPlvvhddvGiGrsGilla
IDSVVAHAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVL
. .| . . ||| . | .|..| .||. |. ..| |.
tlvlvsrledlGrvdvaavvirlreyraalvqavvqlrllyealv
|
|||||||||
subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 610-849 | 1e-34 | 114.8 | In-house | 29-270 (285) | alignment | ||
Range on Protein: 610-849
Range on HMM: 29-270/285.0
VAQEEINFKKNRYKNILPYDSVRVKLEvindNPHSDYFNASYIPSFDND-KAYIASQGPNKASMDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNK
. | | ||| .. . || |. | || ||.. .| .||..||| .. |||.|..||... . |. | || || |.|.|
ytayeanpdlnryadvrcieetrvvlk....nhdrdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyypek
PGDSVKFGYIRVELVS--LEACTGGIKRTMTMLKGDDCRTV----TQFHFTEWPDKGVPKHTSALLKFIKEVKADHGQyTHPLIIHCSAGVGRTGVVISI
|. |||| . | || .| | ..|... .|. . . . |||. |. . .... | || . .|. .||||||||| .. |
lgevvkfgkyeitlteckeeaiagtilnaltvintedasseplymnhvqvpwwpdqlapedarpmielykwvkkvnpk.ekpicvhcsagvgrtatfvgi
DSVVAHAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLEDL
| . ..... | ..| | ||.. |. |.| ..| .
dyatirimenpniemldivremramrfqavqshmqflflyvvlmeyf
|
|||||||||
subfamily_eak_pd | Subfamily eak | 610-855 | 2.5e-22 | 73.7 | In-house | 46-311 (332) | alignment | ||
Range on Protein: 610-855
Range on HMM: 46-311/332.0
VAQEEINFKKNrYKNILPYDSVRVKLEVINDNPHsDYFNASYIPSFDNDKAYIASQGPNKASMDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKP
... . ..| .|.||| |.| |. | ||| . . . || . ... . ||.|| ... .| .. . | . | ||.|.|
etarleavnrn.vvkivpydrylvrltssqlnrl.GyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledvelkleksdkyfpdkt
GDSVKFGYIRVELVSLEACTGGIKRTMTMLKGDDCRTVTQFHFTEWPDKGVPKHTS--ALLKFIKEVKAD-------------HGQYTH-----PLIIHC
. .|||.. || . | . . ||.. | ... | . .|| || | .||| . .| | || .
reelkfGildverkefvkrniletrllelskGnethrvlhykvfGwtettlpkyedflalrkvmkevGvlllivmksallsstlkkyihtppsfapiiqs
SAGVGRTGVVISIDSVVA--HAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLEDLLWRNTL
. | |.|| . || .. .| . . | ... ...|| . | .. |..||| .||. || ||
arGsaraGvfvvidllirlidnkkknlysvedlilkvkskrihsvlvalqhsfiyeivldyllrrnnr
|
|||||||||
subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 611-847 | 1.6e-70 | 232.0 | In-house | 2-238 (239) | alignment | ||
Range on Protein: 611-847
Range on HMM: 2-238/239.0
AQEEINFKKNRYKNILPYDSVRVKLEVINDNPHSDYFNASYIPSFDN-DKAYIASQGPNKASMDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKp
|.. .| |||| ||. || || || ....||||| ||||. .| |||||.|| ..| |||||.||| | |.| | || | || .|||.
akkrvnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpds.
gdSVKFGYIRVELVSLEACTGGIKRTMTMLK--GDDCRTVTQFHFTEWPDKGVPKHTSALLKFIKEVKADHGQYTHPLIIHCSAGVGRTGVVISIDSVVA
. |. .|| | | . | ||. | . . | | |.||| |||||||....|.| . ... | ..| .||||||||||| .. ||...
..tskycnlrvtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlr
HAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLE
.|| . ||.||.| ||. ||.|||| ||| ||. ||||
qakkqktvdifnyvkairedrphmvqtseqyvfihlavle
|
|||||||||
subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 611-847 | 2e-70 | 231.7 | In-house | 3-239 (239) | alignment | ||
Range on Protein: 611-847
Range on HMM: 3-239/239.0
AQEEINFKKNRYKNILPYDSVRVKLEVINDNPHSDYFNASYIPSFDN-DKAYIASQGPNKASMDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKp
|.. .| |||| ||. || || || ....||||| ||||. .| |||||.|| ..| |||||.||| | |.| | || | || .|||.
akkrvnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpds.
gdSVKFGYIRVELVSLEACTGGIKRTMTMLK--GDDCRTVTQFHFTEWPDKGVPKHTSALLKFIKEVKADHGQYTHPLIIHCSAGVGRTGVVISIDSVVA
. |. .|| | | . | ||. | . . | | |.||| |||||||....|.| . ... | ..| .||||||||||| .. ||...
..tskycnlrvtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlr
HAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLE
.|| . ||.||.| ||. ||.|||| ||| ||. ||||
qakkqktvdifnyvkairedrphmvqtseqyvfihlavle
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 612-772 | 8.9e-37 | 121.5 | In-house | 29-191 (297) | alignment | ||
Range on Protein: 612-772
Range on HMM: 29-191/297.0
QEEINFKKNRYKNILPYDSVRVKLEviNDNPHSDYFNASYI--PSFDNDKAYIASQGPNKASMDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKP
. . ..||||..|| .|. |||| . . .|| || |. | ..| || .||| .|..||||..|....| .|.||.||.|. . || |||.
krnsslrknryrdilatddtrvkll..rviterdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrdkcapywpsvv
GDSVKFGYIRVELVSLEACT--GGIKRTMTMLKGDDCRTVTQFHFTEWPDKGVPKHTSALLKFIK
.. | | . || .| . | .... .. | |. | |||.||| | .|
qerlkagdvvveflsstsdefdrviltelqliyrsesrvvrhvqflswpdhGvpsdledlvrfqa
|
|||||||||
subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 613-850 | 1.4e-38 | 127.3 | In-house | 52-290 (305) | alignment | ||
Range on Protein: 613-850
Range on HMM: 52-290/305.0
EEINFKKNRYKNILPYDSVRVKLEvinDNPHSDYFNASYIPS-FDNDKAYIASQGPNKASMDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPGD
.|. ||||... | |||. . . ||| | |. . .| .|..||| ..|.|| || |..| | |. | | |.|| .||| |.
adiaitknryqdvpcqdqsavkld...kpspsdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkveqivmlcktvelgklkcaqywpaaqge
SVKF-GYIRVELVSLEAC---TGGIKRTMTML--KGDDCRTVTQFHFTEWPDKGVPKHTSALLKFIKEVKADHgqytHPLIIHCSAGVGRTGVVISIDSV
... . | || || |. |. | ||. .| ....|||||.||| . |... .. . |...|||||.|||| ...|. .
klelksgivvenvsgskpmerdaeiqitllnltysgdqkmsvrhlqwtewpdrgvppckltslellsairgsk....vpivvhcsagigrtgtivaieyi
VAH-AKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLEDLL
. . |. . . ..| .|..| . .|.. || ||. .|. .|
lekiaenkpcppmpelvkalrdqrafsiqndvqylfihrvmlnyfl
|
|||||||||
subfamily_ptpA1_pd | Subfamily ptpA1 | 613-801 | 1.2e-35 | 118.1 | In-house | 44-248 (418) | alignment | ||
Range on Protein: 613-801
Range on HMM: 44-248/418.0
EEINFKKNRYKNILPYDSVRVKLEVINDNPHSDYFNASYIPSfDNDKAYIASQGPNKASMDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPGDS
.. | |||| |||| . ||.|. |.|. ||| || || | .|..||| .. |||||||.. . | |... | .||| .|||.. |
kkhntsknrytnilpvnhtrvqlkkiqdkegsdyinanyidg.aypkqfictqgplpntiadfwrmvwenrcriivmlsresencrikcdrywpeqigge
---------VKFGYIRVELVSL--EACTGGIKRTMTMLKGDDCRTVTQFHFTEWPDKGVPKHTSALLKFIKEVKADHGQY------THPLIIHCSAGVGR
|| |||| . . | | . . . | .||... |||. .| || . .... . . | |.|.||||||||
qfsiygngnevfgtysvelveviqdpereiitrnirltfegetrditqyqyegwpdhnipdhtqpfrqllhsitnrqnqiipssdrnvpiivhcsagvgr
TGVVIS
|| . .
tgtfct
|
|||||||||
subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 615-847 | 2.2e-39 | 130.0 | In-house | 47-285 (305) | alignment | ||
Range on Protein: 615-847
Range on HMM: 47-285/305.0
INFKKNRYKNILPYDSVRVKLEviNDNPHsDYFNASYIPSFDNDKAYIASQGPNKASMDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPGDSVK
. .|||||.. | ||||| . || .| | |. . | | .| .| | . . ||| | .|..| .| |. .|.| || .|.. | .| ..
qeagknrykdvgcldnnrvkle..gpwph.eyihanyvstptnpkrfictqaplektcadfwymclqdkveaifmlcnllekgakkcleyfaskdkdvle
FGY----IRVELVSL------EACTGGIKRTMTMLKGD--DCRTVTQFHFTEWPDKGVPKHTSALLKFIKEVKADHGqythPLIIHCSAGVGRTGVVISI
| | | . | . . ...|. ...| . | ||..|. .|||.||| |.|..... .. .| |...|||||.|||| |. .
feekgqkisvkfessvtlkfrkdakakvtetvlviegpgekarkvthyhwidwpdrgvpaadlailellekarpskg....pivvhcsagigrtgsvvml
DSVVAHAKTTRMVDV-FNFVTNIRQKRPYMVQTQEQYAFIYGAVLE
. .. . .... . ||..| .||..|| |.. .|.
eyildqllagqiiedtdkilqkireqrnnsiqtdaqylfvhqviln
|
|||||||||
subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 615-850 | 6.4e-18 | 59.4 | In-house | 46-280 (303) | alignment | ||
Range on Protein: 615-850
Range on HMM: 46-280/303.0
INFKKNRYKNILPYDSVRVKLEvindnpHSDYFNASYIpSFDNDKAYIASQGPNKASMDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKpGDSVK
|..|||. ... | .||| | | |||. .| .| | .| | . |||.|. ...| . .. | ||. .|.. | .|
knmdknrfvdvicldhskvkls......dssyihasyl.eldsskkailtqlplshtaadfwqmiieqkvkcvlllltdseydklggdsvfprn.qdflk
FG--YIRV-ELVSLEACTGGIKRTMTMLKGDDCRTVTQFHFTEWPDKGVPKH-TSALLKFIKEVKADHGQYT--HPLIIHCSAGVGRTGVVISIDSV--V
| .||| |. .| | . ... .|| . |. .|| . .| . .. ..| | .... .|. .| . .|.||.| ...
feersirvgefkrvelgdgwvlkvlsvsngdyksflhvhhykawphnsipsdgspkfvkqiwqlqsvlrkysdstptvymslsgcgragtfalfetahls
AHAkTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLEDLL
|. .|. . . |.|. | . || |....| . | .|
lhs.eqasldlvkclenvrngrlhavqnlsqfsvvytllaehvl
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 616-847 | 5e-80 | 263.7 | Pfam-A | 1-235 (235) | alignment | ||
Range on Protein: 616-847
Range on HMM: 1-235/235.0
NFKKNRYKNILPYDSVRVKLeviNDNPH-SDYFNASYIPSFDNDKAYIASQGPNKASMDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPGDSVK
|.||||||.|||||. |||| ..... ||| ||.|. .....|..||.||| | ...|||||||||.|..|.|.|.|.| .. || .|||.. ..|..
nkkknRykdilpydktrvkl...kgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeeslt
FGYIRVELV-SLE-ACTGGIKRTMTMLKGDDC---RTVTQFHFTEWPDKGVPKHTSALLKFIKEVKADHGQYTHPLIIHCSAGVGRTGVVISIDSVVAHA
.| |.|||. . . .... . |.... | .. |.|.|.|.|.|||.|||.....||..|..|. .. . ..|...||||||||||.....| .. ..
ygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleql
KTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLE
.... |||...| ..|..|| |||. |||.|.| |.||
eaeeevdvlqivkelRkqRpgmvqsleqYiflykaile
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 616-847 | 5e-80 | 263.7 | In-house | 1-235 (235) | alignment | ||
Range on Protein: 616-847
Range on HMM: 1-235/235.0
NFKKNRYKNILPYDSVRVKLeviNDNPH-SDYFNASYIPSFDNDKAYIASQGPNKASMDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPGDSVK
|.||||||.|||||. |||| ..... ||| ||.|. .....|..||.||| | ...|||||||||.|..|.|.|.|.| .. || .|||.. ..|..
nkkknRykdilpydktrvkl...kgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeeslt
FGYIRVELV-SLE-ACTGGIKRTMTMLKGDDC---RTVTQFHFTEWPDKGVPKHTSALLKFIKEVKADHGQYTHPLIIHCSAGVGRTGVVISIDSVVAHA
.| |.|||. . . .... . |.... | .. |.|.|.|.|.|||.|||.....||..|..|. .. . ..|...||||||||||.....| .. ..
ygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleql
KTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLE
.... |||...| ..|..|| |||. |||.|.| |.||
eaeeevdvlqivkelRkqRpgmvqsleqYiflykaile
|
|||||||||
0041856 | (Phosphotyrosine protein) phosphatases II | 616-857 | 5.7e-45 | 148.5 | In-house | 1-179 (182) | alignment | ||
Range on Protein: 616-857
Range on HMM: 1-179/182.0
NFKKNRYKNILPYDSVRvklevindnpHSDYFNASYIPSFDNDKAYIASQGPNKASMDDFWRMVWQENVTTIAMVTklkegdkikCGKYWPNKPgdsvkf
|..||||..||||| | ..|| ||... . .. .|| ||| . .. ||.||......||| ..| . |||..
nldknrysdilpydhsr..........dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt.........eelywpell......
gyirvelvsleactggikrtmtmlkgddCRTVTQFHFTEWPDKGVPKhTSALLKFIKEVKAdhgqYTHPLIIHCSAGVGRTGVVISIDSVVAHakttrMV
|...|.... ||| ||| .. ||.||.||.. .| ..||||||||||... .. . . |
............................erlgiqylylpwpDhgvpd.ldelldfieevle....eggpvlVHCsaGvgRtgtlvaaylmkkl.....gv
DVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLEDLLWRNTLIP
.... | .|..|| ||.| .|| |.. |.|| ||...| ..
sleeavklvrsrRpgmvitpnqyfflqlallellllkktrpk
|
|||||||||
subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 616-844 | 2e-37 | 123.7 | In-house | 33-254 (267) | alignment | ||
Range on Protein: 616-844
Range on HMM: 33-254/267.0
NFKKNRYKNILPYDSVRVKLEVINDNphsdYFNASYIPSFDNDKAYIASQGPNKASMDDFWRMVWQENVTTIAMVTKLKEgDKIKcgKYWPNKPGDSVKF
| ..||. . |||| || | ... | ||||. .. .|.|. |.| | .. ||. .. ...|..| ..|| . |.|. ..|| | |.. |.
nqernrlddnlpyddtrvilrtkeee....yinasyvegyktknafivtqdplkntitdfltvihdqkvpvivlltkvft.dnir..lfwPPkmgqakky
GYIRVELvSLEACTGG--IKRTMTMLKGDDCRTVTQFHFTEWPDKGVPKHTSA-LLKFIkeVKADHGQYTHPLIIHCSAGVGRTGVVISIDSVVAHAKTT
. || ||| | .| . .. || ... .| . | |. . | . . .||...||.||||.| . ||| . |||
qdltveh.slekeendyqiitlelkfknesahnvtlyyykkwnintnnkpylkplfgil..aknqlengnrPlvvacsdGvGrsGtflvidsqlerakte
RMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGA
..|.|.|. .||..|. .|.|.|.| .|.
gvsdifdflrkirsqriglvdtkeryiyihel
|
|||||||||
subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 616-842 | 1.4e-30 | 101.0 | In-house | 52-283 (310) | alignment | ||
Range on Protein: 616-842
Range on HMM: 52-283/310.0
NFKKNRYKNILPYDSVRVKLEvINDNPHSDYFNASYIPSFDNDKAYIASQGPNKASMDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKpGDSVKF
...|||| ... |. ||||. |. . || | |. . ...| |||| . .. |||||..|| .| .. | | . || ||| | . .
ymhknrysdvvcldtsrvklk.idksryedyihanyvktnylrstficsqgplqhtiidfwrmifqeraesilllckvgeegrpkcvgywpsl.gvtety
GYIRVELVS-----LEACTGGIKRTMTMLKGDDC------RTVTQFHFTEWPDKGVPKHTSALLKFIKEVKADHGqythPLIIHCSAGVGRTGVVISIDS
| ||| .| .| | . . |. |. .. .|||.||| . . || | ..|||||..|..||....
gcirvtnlsesseefeicnlavtfvpdnvpvdeqpanlkelrvslikwpnwpdrgvpdekchtvpqrllaqvrhg....pcvvhcsagkdrlyvvvalkl
VVAHAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIY
. ... ||. . .|.....| .||. || .|
kidkldrglkvdaeevktellksraiciqtelqyliid
|
|||||||||
subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 616-846 | 6.9e-25 | 82.1 | In-house | 51-282 (302) | alignment | ||
Range on Protein: 616-846
Range on HMM: 51-282/302.0
NFKKNRYKNILPYDSVRVKLEVINDnphsDYFNASYI--PSFDndKAYIASQGPNKASM---DDFWRMVWQENVTTIAMVTKLKEGDKiKCGKYWPNKPG
| |||. ... .|| .|||| .| .| ||| . |.. . | .| |.. | ..|||||.||..... .. . .| .| ...|.| |
nlkknqsedvpildsnlvkleaepd....syvnaskvevPelt..rsiilaQlpkvdsedsveeFWrmvfqekivsvvilvgeeelkk.tlselfpkksg
DSVKFGYIRVELVSLEACTGGIKRTMTMLKGDDCRT---VTQFHFTEWPDKGVPKHTSALLKFIKEVKADHGQYTHPLIIHCSAGVGRTGVVISIDSVVA
| ...| ..| | . .| . . ..| .. ..| |..| ||.. ..| | ...| | . . .....| |.|| |.... .|
dykeygkmfvNnrkVekaeeektryviEvlPegcsnsvlanvyvltnWkqkkvpvkyaeliktaakvfakkikadentvivSknGaGRagafltlavave
HAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVL
. .. . . . |..||..|| .|.. .||...| |.|
klqkgkepnikeivksiRsqRpravdslkQyvslyiall
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 616-712 | 1.5e-21 | 71.5 | In-house | 47-157 (350) | alignment | ||
Range on Protein: 616-712
Range on HMM: 47-157/350.0
NFKKNRYKNILPYDSVRVKLE-------VIN-DNPHSDYFNASYIP------SFDNDKAYIASQGPNKASMDDFWRMVWQENVTTIAMVTKLKEGDKIKC
| ||||||||||. ||||. .. .|| ||.|. . . | ||| |.| . .|||.... . .|. | ..|.. | . ||
lfaknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekc
GKYWPNKPGDS
.||.. |
yrYWqegsydd
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 616-708 | 2.4e-13 | 44.1 | In-house | 48-156 (349) | alignment | ||
Range on Protein: 616-708
Range on HMM: 48-156/349.0
NFKKNRYKNILPYDSVRVKLEVINDNP--------------HSDYFNASYI--PSFDNDKAYIASQGPNKASMDDFWRMVWQENVTTIAMVTKLKEGDKI
| |||||.||||. ||||. .. || || |. . .. .| ||| | | ...|||.... ..| . ... || .
lfaknrykdilPyehsrvklkkslksskvikastsesdsgklddyinanylkltrisvekkyiatqaPlPstvddfykvillngvklvlsLnddkelsle
KCGKYWPNK
|| .|| .
kcdiywqel
|
|||||||||
subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 617-847 | 4.1e-67 | 220.9 | In-house | 4-237 (237) | alignment | ||
Range on Protein: 617-847
Range on HMM: 4-237/237.0
FKKNRYKNILPYDSVRVKLEVINDNphSDYFNASYIPSFDN-DKAYIASQGPNKASMDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKpGDSVKF
|||| || || || |. . ||| ||.|. .|| | |||.||| ..| ||||.|||||. . | |.| | ||...|| ||||. . .
kiknrygnivaydhsrvvlkgagsg..sdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpst.dqpaay
GYIRVELVSLEACTGGIKRTMTMLK---GDDCRTVTQFHFTEWPDKGVPKHTSALLKFIKEV--KADHGQYTHPLIIHCSAGVGRTGVVISIDSVVAHAK
| . | | |. . |.... | . | . |..|| |||.|||..|.|||.| |.. .. | . . | ||||||||||||... ||... .||
gvltvslkkkeefsdytvrslllskrltlkevrlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlrqak
TTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLE
..||..|.| .| . |||..||..|| ||. ..||
ekkvvdiynyvysieedrpyiiqtkdqyvfihqtile
|
|||||||||
subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 618-844 | 6e-32 | 105.6 | In-house | 52-277 (301) | alignment | ||
Range on Protein: 618-844
Range on HMM: 52-277/301.0
KKNRYKNIlPYDSvRVKLEVINDNPHSdYFNASYIPSFDNDKAYIASQGPNKASMDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPGDSVKFGY
.|.||... | . .|||.| | .||. . . .||.||| |....||| |. | .| .|.|... | . || .| | |...... |
dkhryptv.PckP.stavevivdGkrv.PihanwiptsGhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkisekldigr
IRVELVSLEACTGG--IKRTMTMLKG---DDCRTVTQFHFTEWPDKGVPKHTSALLKFIKEVKADhgqyTHPLIIHCSAGVGRTGVVISIDSVVAHAKTT
...... | .|||. . . |||| . ..||.|.|||| | .... || .|...|||||.||. |. . . . ..
fkikiknkelilnkkiskrtlevedstgkfatrtvthyqysewtdrgvPkshaelfdlmelvkks....ekPivvhcsaGiGrsvafigteylarevead
RMVDVFNFVTNIRQKRPYMVQTQEQYAFI-YGA
. ... . . ..|..| |||..| .. |.
ptieltealkhlrehrwngvqtnsqlywmtlGt
|
|||||||||
subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 619-856 | 5.4e-27 | 89.7 | In-house | 22-257 (290) | alignment | ||
Range on Protein: 619-856
Range on HMM: 22-257/290.0
KNRYKNILPYDsVRVKLEVINDNPHSDYFNASYIpSFDNDKAYIASQGPNKAS-------MDDFWRMVWQENVTTIAMVTKLKEGDKI----KCGKYWPN
..|... | . || |.. .||. |... .. |. . |..| | .. . .|| |. ||.|. . |. . .| .. | || |.
dqRlevpLvea.trvvLkgygkrfnddyiHAnrv.tcpnglrliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCakYvpe
KPGDSVKFGYIRVELVSLEACTGGIKRTMTMLKGDD-CRTVTQFHFTEWPDKGVPKHTSALLKFIKEVKadhgQYTHPLIIHCSAGVGRTGVVISIDSVV
. |...||. . |. | |. . ..|.... .|. ||| . .| . |...| ||. |. || ... | |.|| |. | .. .|.
svgeelkfkgltvkCkskekeddvetRelvvkfddeeeftvtHsllkgWnklnvqedtktllsliqkvk....asktpvivHcvdGiSrsAalaaiilgy
AH-AKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLedllwrntlI
|.|. | . . . ..|..| ........||. ... .
Qkiaetsgsvkledvlkalrkqralaitsalelafvdagiv.........l
|
|||||||||
0044763 | (Phosphotyrosine protein) phosphatases II | 627-844 | 4.9e-34 | 112.9 | In-house | 1-166 (178) | alignment | ||
Range on Protein: 627-844
Range on HMM: 1-166/178.0
PYDSVRVKLEVINDNPHSDYFNASYIPSFdndkAYIASQGPnkasmDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPGdsvkfgyirvelvsle
|.| ||.|. . . . |||.|||.| . |..|..| |..........|.| ..|. .|. ..|| .||| . |
pldrtrvllsnleglersdyinaseilpg....lylgslpp.....addlellkelgithivnlteelelgflkcdpywpeeag................
actggikrtmtmlkgddcrtvTQFHFTEWPDKGVPKHTSALLKFIKEVKADHGQYTHPLIIHCSAGVGRTGVVISIDSVVAHakttRMvDVFNFVTNIRQ
|.... .|| ||| .. .|.|.. ... . . .| ..||||||||.|... .. . . .. .... . .|.
.....................iqylhipipDhgvpdllehflefvefieealdekggpvlVHCsaGvgRsgtlvaaylmkkl....gl.sleeaielvre
KRPyMVQTQEQYAFIYGA
.|| .|....|. ..|
rRp.ivpnpgqlrqLyef
|
|||||||||
0046846 | (Phosphotyrosine protein) phosphatases II | 637-845 | 5.3e-37 | 122.6 | In-house | 5-169 (176) | alignment | ||
Range on Protein: 637-845
Range on HMM: 5-169/176.0
VINDNPHSDYFNASYIPSFdndkAYIASQGPNKASMDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNkpgdSVKFGYirvelvsleactggikrtm
.. .....|| ||..| . ..|| ||| .. ||..|......|.. ..|...| ...|| ||| |.|.
llgldldldyinanlilgs....rpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpe....leklgi...................
tmlkgddcrtvtQFHFTEWPDKGVPKHtSALLKFIKEVKADHGQYtHPLIIHCSAGVGRTGVVISIDsvvaHAKTTRMVDVFNFVTNIRQKRP-YMVQTQ
|.... ||| ||| . ..||....... . .| ..|||||.||||... .. .. . ..|.. . .|..|| ..|||.
............qylhlpwpDhgvpdl.elllellefirealkeg.gpvlVHCsaGigRtgtlvaay....llelekglsveealalvreqRplgavqtp
EQYAFIYGAV
||| |.| ..
eQyrflyefe
|
|||||||||
0051429 | (Phosphotyrosine protein) phosphatases II | 642-848 | 8.8e-48 | 158.6 | In-house | 2-224 (272) | alignment | ||
Range on Protein: 642-848
Range on HMM: 2-224/272.0
PHSDYFNASYIPSFDN---DKAYIASQGPNKASMDDFWRMvWQENVTTIAMVTKLKEGDKIKCGKYWP----------NKPGDSVKFGYIRVELVSLEAC
| |.|.||.... . . ......|.|| ... .||||. ......|| ..... | .. || .||| . .. .|..|| |.| | .
plsgyiNardvggygrvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseell
TGGIKRTMTML---KGDDCRTVTQFHFTEWPDKGVPKHTsaLLKFIKEVKAdhgqyTHPLIIHCSAGVGRTGVVISIDSVVAHAKTTRMVD--------V
. | |.... . .. |.|...|.| ||| |||... ||...... . .|...|||||..|||.|. .. ... . .|| .
ldyilrellltlllsagearevmhlhytdwpdhgvpqea..llellellld.....ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlyl
FNFVTNIRQKRPYMVQTQEQYAFIYGAVLED
...| .|..||..|||.|||.|.| |.||
eeaveelraqrpgavqteeqylflyeallel
|
|||||||||
0043147 | (Phosphotyrosine protein) phosphatases II | 642-842 | 1.3e-38 | 127.7 | In-house | 3-154 (172) | alignment | ||
Range on Protein: 642-842
Range on HMM: 3-154/172.0
PHSDYFNASYIPSFDNDKAYIASQGPNKASMDDFWRMVWQENVTTIAMVTKLkegdkikcgkywpnkpgdsvkfgyirvelvsleactggikrtmTMLKG
..||| ||||.. . .|| ||| ..|||||......|.| ..|.| . ..
egsdyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltel...........................................lydpe
DDCRTVTQFHFTEWPDKGVPkHTSALLKFIKEVKA-DHGQYTHPLIIHCSAGVGRTGVVISIDSVVahakttRMVDVFNFVTNIRQKRPYMVQTQEQYAF
. .|.. |.... ||| ||| ... ||.|.. .. . . .| ..||||||||||... .. . . ..... | .|.|||..||...|| |
llerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml......lglsleeavalvrekRpgavqnpsqyrf
IY
.|
ly
|
|||||||||
0051082 | (Phosphotyrosine protein) phosphatases II | 642-845 | 2.5e-34 | 113.4 | In-house | 1-149 (151) | alignment | ||
Range on Protein: 642-845
Range on HMM: 1-149/151.0
PHSDYFNASYIPSFdndkaYIASQGPnkasMDDFWRMVWQENVTTIAMVTKLKEGDkiKCGKYWPNKPgdsvkfgyirvelvsleactggikrtmtmlkg
|.|||.|.||. .. ...|.|| ..||..........|| ......| . .| .|.|.
plsdyinfsyvtgg.....lyrsggp....ladflellkelgiktivnlrseeerg..ycpeylpelg................................
ddcRTVTQFHFTEWPDKGVPKHTSALLKFIKEVKAdhgQYTHPLIIHCSAGVGRTGVVISIDSVVAHakttrmVDVFNFVTNIRQKRPYMVQTQEQYAFI
..|...... ||| |.| .. |.|.|.... . . .|...|||||.||||... .. . . |... . .|.|||..||. .|. |.
...ievlhipildwpdpglplsfdavleflellld...kkngpvlvHCsaGkgRTGtlvalylmllg......vsleealeeyrlkrpgvvqpnqqflfq
YGAV
. |.
lfal
|
|||||||||
0036282 | (Phosphotyrosine protein) phosphatases II | 644-842 | 8.3e-44 | 144.7 | In-house | 2-163 (174) | alignment | ||
Range on Protein: 644-842
Range on HMM: 2-163/174.0
SDYFNASYIPSFDNDKAYIASQGPNKasmddFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNkpgdsvkfgyirvelvsleactggikrtmtmLKGDD
|||.|||.. . . .||.||| . ||.|......||. |....|| .. || ||| |. |
sdyinaspldlsyitprliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe...............................lredl
CRTVTQFHFTEWPDKGVPKHTSaLLKFIKEVKADHGQ-YTHPLIIHCSAGVGRTGVVISIDSVVAHAKtTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIY
|.. |.... ||| ||| . ||.|.|.|. . . .|...||||||||||... .. . . . ...||....| .|..||.||||..|| |.|
erlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtpsQyrfly
|
|||||||||
0049260 | (Phosphotyrosine protein) phosphatases II | 652-842 | 3.6e-37 | 122.7 | In-house | 2-143 (152) | alignment | ||
Range on Protein: 652-842
Range on HMM: 2-143/152.0
IPSFDNDKAYIASQGPNKASMDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWpnkpgdsvkfgyirvelvsleactggikrtmtmlkgddcrtvtQFH
|. . . ...|| ||| ...|||||... ..||| |.|.| | .|.|| .|. |..
idgyampfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi...........................................qyl
FTEWPDKGVPKHTSALLKFIKEVKADHGQYTHPLIIHCSAGVGRTGVVISIDSVVahakttRMVDVFNFVTNIRQKRPYMVQTQEQYAFIY
.. ||| |||... || ... .. . .| ..||||||||||... .. . . |.....| .|.|||..|....|. |.|
hlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpgqlrfly
|
|||||||||
subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 652-883 | 2e-20 | 68.0 | In-house | 26-248 (255) | alignment | ||
Range on Protein: 652-883
Range on HMM: 26-248/255.0
IPSFDNDKAYIASQgpnkaSMDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPGDSVKFGYIRVELVSleACTGGIKRTMTMLK----GDDCRTV
|. |... . | ..| |.... | . ....|.. ..| .. || .|.| . . |. . | . . . ||.... .||
kPekdkkrknlysl.....tvdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdeklkladvnvtttk..ssadvvlrtleitstlgekkkthtv
TQFHFTEWPDKGVPKHTSALLKFIKEVKADhgqytHPLIIHCSAGVGRTGVVISIDSVVA------HAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFI
. .... |..| |. . .|. .| |. .....|||.|.||. . ...| . | .| ......|.||. ..| | ||
khysykGWieknaPelareilnilkvvrds.....ksvvvhCstGiGrsaafvlaelvyqkmirsldttetveldylslleelrskrkraihtPlqlafs
YGAVLEDLlwrntlIPVIHFTDHLQDLHSSgDGHGRSKMTKE
||. . | .. ...|... | | | | |.
ilmvldlv......fpkgeleakyqeirks.ylharqmmhkd
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 657-720 | 8.9e-08 | 25.9 | In-house | 234-293 (440) | alignment | ||
Range on Protein: 657-720
Range on HMM: 234-293/440.0
NDKAYIASQGPNKASMDDFWRMVWQENVTTIAMVTKLKegDKiKCGKYWPNKpGDSVKFGYIRV
. .|.||.| | ... ||||.| . ...|| |. .|. || | ||| . || || . |
kknafiatqmpldstvldfwrlvhdyristiimlnqln..dk.tcsiywpvn.trsvtfgpftv
|
|||||||||
subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 658-842 | 5.8e-23 | 76.1 | In-house | 4-197 (199) | alignment | ||
Range on Protein: 658-842
Range on HMM: 4-197/199.0
DKAYIASQGPNKASMDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPGDSVKFGYIRVELVSLEACTG----GIKRTMTMLKGDDCRTVTQFHFT
.. |||.| | . .| |||.|||. | || . . ||| . |.| . | .. . . | | .... ||
qrryiatqhplretmadfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqft
EWPDKGVPKHTsALLKFI---KEVKADHGQY-THPLIIHCSAGVGRTGVVISIDSVV-AHAK-TTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIY
| .| |. . .. |. .|| . | |.|.||| | | ||| ...| | .| . | .||.|. .|| | .. . ..| |||
swkekttpnva.lfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiy
|
|||||||||
subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 658-842 | 9.8e-23 | 75.4 | In-house | 3-196 (198) | alignment | ||
Range on Protein: 658-842
Range on HMM: 3-196/198.0
DKAYIASQGPNKASMDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPGDSVKFGYIRVELVSLEACTG----GIKRTMTMLKGDDCRTVTQFHFT
.. |||.| | . .. |||.|||. | || . . ||| . |.| . | .. . . | | .... ||
qrryiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqft
EWPDKGVPKHTsALLKFI---KEVKADHGQY-THPLIIHCSAGVGRTGVVISIDSVV-AHAK-TTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIY
| .| |. . .. |. .|| . | |.|.||| | | ||| ...| | .| . | .||.|. .|| | .. . ..| |||
swkekttpnva.lfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiy
|
|||||||||
subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 665-847 | 2e-23 | 77.3 | In-house | 97-286 (302) | alignment | ||
Range on Protein: 665-847
Range on HMM: 97-286/302.0
QGPNKASMDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPGDSVKFGYIRVELVSLEACTGG--IKRTMTM---------LKGDDCRTVTQFHFT
| | ... .| .. | ||. .. .....|... || .|. .| |. .||| |. ||.. |..... | . .|| ..|.
ivpkkstlekhwalieqynvaivvqlcsfvedeekkcaeyysdkvggelkfgrytvktvsvktdleeftdkksfklytveiknekkkkkvkktvdilafs
EWPDKGVPKHTSALLKFIKEVKAdhgqYTHPLIIHCSAGVGRTGVVISIDSVVAHAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLE
|||.| ||.. . |. .| .. | . ...|||||||||| ...| . .. .. |. . |. .|| | ||...| .. |
awpdhGapkeaytaldilkfces....ykknvlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqdeqqliylllcvtk
|
|||||||||
subfamily_Cele-PTP-5_pd | Subfamily Cele-PTP-5 | 665-847 | 1.4e-08 | 27.8 | In-house | 124-307 (346) | alignment | ||
Range on Protein: 665-847
Range on HMM: 124-307/346.0
QGPNKASMDDFWRMVWQENVTTIAMvtkLKEGDKIKC--GKYWPNKPGDSVKFGYIRVELVSLEACTGGIKRTMTMLK-GDDCRTVTQ-FHFTEWPDKGV
| |.. ..||| |..||.. . . . ||.| . .. | | . .. . . |. .| |. . | | . |
qmenesfvedfwymiyqeqihlvyl...mvpddklkntttslfndenggyqytgkmfinnrradvsgdpkeytievlpegnsdsvicqvhhhapwkhlqq
PKHTSALLKFIKEVKADHGQYTHPLIIHCSAGVGRTGVVISIDSVVAHAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLE
| .| ..|.|.. .... . . . | ||. | . .... . ||.|.|| |.. ||| || |..
ppktlpiikmihqflsekqvqnagvcvvslfgcgracsfigalyainqlnngiepniceimknikqqrpggvesfaqyasiyaivfd
|
|||||||||
subfamily_hpo-7_pd | Subfamily hpo-7 | 670-847 | 6.4e-17 | 56.3 | In-house | 45-225 (263) | alignment | ||
Range on Protein: 670-847
Range on HMM: 45-225/263.0
ASMDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPGDSVKFGYIRVelVSLEACTGGIKRTMTMLK--G--DDCRTVTQFHFTEWPDKGVPKHTS
.| |.... | . ....|.. .| .. || .|.| . . |. . | .. .. ...| .|. | .||... .. |..| |. .
qtidkfyqtivqtktevvvmLcDfneegvekcssyfPlekdekqklanvnv..cttkvqsdvllktlellstlgeKkkthtvkhysykgWiekndpelar
ALLKFIKEVKADhgqytHPLIIHCSAGVGRTGVVISIDSVVA----H--AKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLE
|. .| .. ..|..|||.|.||. ...| | .| ......|..|. ..| | || ||.
eilnilkvarns.....kslvvhcstGiGrsaafsvaElvyqkmirsldttstveldylsLleelrssrkraihtPmqLafsilmvLd
|
|||||||||
0048076 | (Phosphotyrosine protein) phosphatases II | 704-845 | 6e-23 | 76.5 | In-house | 2-139 (145) | alignment | ||
Range on Protein: 704-845
Range on HMM: 2-139/145.0
YWPNKPGDSVKFGYIRVELVSLEACTGGIKR--TMTMLKGDDCRTVTQFHFTEWPDKGVPKHTSALLKFIKEVKADHGQYtHPLIIHCSAGVGRTGVVIS
|||.. ... .| . . | . . ||.. ..|. . . |...|.... ||| ||| .. ||.|.. ... . . .| ..||||||||||...
ywpseilpglylgslptaldlellkdlgittvlnltselellerlgiqylylpwpDhgvpdllellleflefieealkeg.gpvlVHCsaGvgRtgtlva
IDSVVAhakttRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAV
.. . . |.... . .|..||..|....|. |.| ..
aylmll.....lgvsleealelvrsqrpgavpnpgqlrflyefe
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 738-885 | 4.8e-35 | 115.7 | In-house | 82-230 (440) | alignment | ||
Range on Protein: 738-885
Range on HMM: 82-230/440.0
MLKGDDCRTVTQFHFTEWPDKGVPKHTSALLKFIKEVKADHGQ-YTHPLIIHCSAGVGRTGVVISIDSVVAHAKTTRMVDVFNFVTNIRQKRPYMVQTQE
...| ..||. |.|. |||||||| .. .||.|..|. . . ||..|||||.|||||.|..||.. .|| . .|.|.|. ..|..|| |||| |
yingiesrtlkqyhyqgwpdkgvpkfagpvlkmiqdvnesqekagngpllvhcsagagrtgviiavdsilreakrsdqidifsfinsmrnnrpqmvqtpe
QYAFIYGAVLEDLLWRNTLIPVIHFTDHLQDLHSSGDGHGRSKMTKEFQ
||||.. |||| || .||| |....... .| . .||.
qyafvheavlegllcgdtliledditerveqiqwpnphtdksplqqefe
|
|||||||||
0048179 | (Phosphotyrosine protein) phosphatases II | 742-842 | 2.4e-21 | 71.4 | In-house | 44-138 (144) | alignment | ||
Range on Protein: 742-842
Range on HMM: 44-138/144.0
DDCRTVTQFHFTEWPDKGVPKHTSALLKFIKEVKADHGQYtHPLIIHCSAGVGRTGVVISIDSVVahakTTRmVDVFNFVTNIRQKRPYMVQTQEQYAFI
. |...|.... ||| ||| ... ||.|.. ... . . .| ..||||||||||... .. .. . . ..... . .|..||..|....|. |.
fleregiqylhlpwpDhgvpdllellleflefieealeeg.gpvlVHCsaGvgRtgtlvaaylmk....klg.lsleealalvrsrrpgavpnpgqlrfL
Y
.
l
|
|||||||||
PTPc_DSPc_SM00012 | 746-847 | 3.2e-33 | 109.4 | In-house | 1-105 (105) | alignment | |||
Range on Protein: 746-847
Range on HMM: 1-105/105.0
TVTQFHFTEWPDKGVPKHTSALLKFIKEVKADHGQYT--HPLIIHCSAGVGRTGVVISIDSVVAHAKTT-RMVDVFNFVTNIRQKRPYMVQTQEQYAFIY
||...|.|.|||.|||......|.....|| . . . .|...||||||||||... .| .. . ... . ||.|..| .|..|| ||||.||| |.|
tvkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylfly
GAVLE
|.||
ralle
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 746-846 | 1.1e-13 | 45.7 | In-house | 216-341 (350) | alignment | ||
Range on Protein: 746-846
Range on HMM: 216-341/350.0
TVTQFHFTEWPDKGVPKHTSALLKFIK-------EVKA-DH--GQYTHPLIIHCSAGVGRTGVVISIDSVVA-------------HAK-TTRMVD-VFNF
| |... |.| .. . .|. .. . | | . . |...||||||||||.....||.. . . .... | ..
vvyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlisii
VTNIRQKRPYMVQTQEQYAFIYGAVL
| ..|..| |||. .|. ||| |.|
vnelrkqrismvqnldqfifiYeall
|
|||||||||
subfamily_PTPDC1_pd | Subfamily PTPDC1 | 749-840 | 8.4e-09 | 30.1 | In-house | 84-167 (182) | alignment | ||
Range on Protein: 749-840
Range on HMM: 84-167/182.0
QFHFTEWPDKGVPKHTSaLLKFIKEVKADHGQYthPLIIHCSAGVGRTGVVISIDSVVAHAKTTRmvdvfNFVTNIRQKRPYMVQTQEQYAF
.. |.| ||. .. .| .| |. . . .|| || |||||.|. | |. |. . .. .|.||| .||.|| .
yvynfgwkDygvasler.iLdivkvvafalqeg..kvavhChaGlGrtGvliacylvyakrltae.....kaiklvrskrpksiqtreqvel
|
|||||||||
0038934 | (Phosphotyrosine protein) phosphatases II | 749-841 | 1.4e-07 | 26.9 | In-house | 81-169 (194) | alignment | ||
Range on Protein: 749-841
Range on HMM: 81-169/194.0
QFHFTEWPDKGVPKHTSALLKFIKEVKADHGQY-THPLIIHCSAGVGRTGVVIsidsvVAHAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFI
... .||.|.. .. ||.|.. |. . . . .|| ||.||||... .|. .. .. . .|.||| ....|... .
eylklpfpddgtvPsleillrfldlvdeflnedpggvvaVHCkaGlgRtGtlv.....aaYLiyrlgmsaeeAialfrekRpgaipnqdyleal
|
|||||||||
subfamily_DSP10_pd | Subfamily DSP10 | 762-825 | 8.6e-06 | 19.7 | In-house | 76-133 (159) | alignment | ||
Range on Protein: 762-825
Range on HMM: 76-133/159.0
KHTSALLKFIKEVKadhgQYTHPLIIHCSAGVGRTgVVISIDSVVAHAKtTRMVDVFNFVTNIR
.. . |.||.|.. . . ...|| ||. | . . | ...| . . | ..|| . |
qyfeealefieear....kkgsrvLvhCqaGisrs.atvviaYlmkhln.lslndaykfvkekr
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 771-849 | 1.1e-17 | 58.8 | In-house | 218-295 (297) | alignment | ||
Range on Protein: 771-849
Range on HMM: 218-295/297.0
IKEVKADHGQyTHPLIIHCSAGVGRTGVVISIDSVVAHAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLEDL
.. ..|.. . .|..||||||||.|||. | ..| . |. || ... .|..|. .||| ||. ..| |||. |
leslraempr.nayllvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqtleqfellydavlkkl
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 778-844 | 1.5e-16 | 54.9 | In-house | 243-310 (319) | alignment | ||
Range on Protein: 778-844
Range on HMM: 243-310/319.0
HGQYTHPLIIHCSAGVGRTGVVISIDSVVAHAKTT-RMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGA
. . ||..||| ||||||.||. | . . ... | ||. . | .|. | |.|.|||.|||
tresqGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefiykv
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 781-847 | 1.6e-08 | 28.3 | In-house | 264-342 (349) | alignment | ||
Range on Protein: 781-847
Range on HMM: 264-342/349.0
YTHPLIIHCSAGVGRTGVVISIDSVVA----HAK-------TTRMVDVFNFVTNI-RQKRPYMVQTQEQYAFIYGAVLE
. .|..||||| |||||.. .|.... . . . |. .. |. |..| ||| |. .|| |.|.
qlstllvhcsaGcGrtGvlvtldlllsileplqnesnkiklqallkDlisiivnelrkqrismvqnlaqfiaiyealLk
|
|||||||||
subfamily_Sponge-PTP-7_pd | Subfamily Sponge-PTP-7 | 786-849 | 6.9e-16 | 52.4 | In-house | 2-65 (69) | alignment | ||
Range on Protein: 786-849
Range on HMM: 2-65/69.0
IIHCSAGVGRTGVVISIDSVVAHAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLEDL
..|||.| |||| |.| .| |. ..||.|| | .|. || || . .| ||. |. | |
vvhcssgtgrtgtfiaimvemarikseklvdifnnvqymrkcrpmmvmneieyifihdalveal
|
|||||||||
subfamily_Sponge-PTP7_pd | Subfamily Sponge-PTP7 | 786-849 | 1.8e-15 | 51.1 | In-house | 1-64 (69) | alignment | ||
Range on Protein: 786-849
Range on HMM: 1-64/69.0
IIHCSAGVGRTGVVISIDSVVAHAKTTRMVDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLEDL
..|||.| |||| |.| .| |. ..||.|| | .|. || || ...| ||. |. | |
vvhcssGtGrtGtfiaimvemarikseklvdifnnvqymrkcrpmmvmneneymfihdalveal
|
|||||||||
0050432 | (Phosphotyrosine protein) phosphatases II | 844-1022 | 7.4e-42 | 139.1 | In-house | 7-190 (308) | alignment | ||
Range on Protein: 844-1022
Range on HMM: 7-190/308.0
AVLEDLLWRNTLIPVIHFTDHLQDLHS-SGDGHGRSKMTKEFQTLKSLCPdppASQTRSGRTRDNHPKNRYGNNLPLQRNRVILdSPDHDYINASQMKGI
|.|| ||.|.| |.|.... ...||. . ...... .||..| |..| ...... .|..|||| . ||. ..||.| ....|||||| ..|
allelllfrdtsilvsslklsvldllkllekaldlglleeefeellsvkp...lleysvallpenkdkNrykdilpydhsRVkl.degsdYInAsyvdgy
----HCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQND-KSCAQYWPDA---NSVQFGSYSVSTLSTSSDGDMTIRQLQVTR
..| || |||.|| ||| || ... ..||||.. .|. . ||||||. .|...| ..| .||. ...|.|.|.|..|
ssklprkfIatqgPlpntvedFwrmvweqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseevlddytvrtleltn
|
|||||||||
subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 844-1003 | 2.2e-12 | 41.1 | In-house | 34-192 (244) | alignment | ||
Range on Protein: 844-1003
Range on HMM: 34-192/244.0
AVLEDLLWRNTLIPVIHFTDHlQDLHSSGDGHGRSKMTKEF-QTLKS-LCPDPpaSQTRSGRTRDNHPKNRYGNNLPLQRNRVILD--SPDHDYINASQM
||| .| | .. | . . . || .| . .. | .. . ||| | . .| ||| | ||.. ||| | | ||||| .
avlsanatknryinilpfdet.rvilssskkegsdyinanyiqgsqniirpdp..svmkdafnpnnswknregaglpfdfnrvplskgsmgntyinasfv
K--GIHCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQNDkscaQYWPDANSVQFGSYSVS
| . .. || || | ||| |.|. . .|.| ..| .||||.. ... ..
gclgrtaeyiltqhpladtsmdfwkmmlerhvnvlvvlgsveeed....eywpdseplewyeedit
|
|||||||||
0051299 | (Phosphotyrosine protein) phosphatases II | 853-1023 | 1.8e-40 | 134.6 | In-house | 2-172 (288) | alignment | ||
Range on Protein: 853-1023
Range on HMM: 2-172/288.0
NTLIPVIHFTDHLQDLHssgdGHGRSKMTKEFQTLKSLCPDppaSQTRSGRTRDNHPKNRYGNNLPLQRNRVILDS----PDHDYINASQMKG--IHCTF
.| |.| ....... |. .| ... .||..| ||.|| ...... |..|||| . ||. ..||.| . ...|||||| ..| . ..|
dteisveellklvlkll....angltglleefeellsllpd...ltlsaallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyidgynlkrkf
MTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQND-KSCAQYWPDANSVQFGSYSVSTLSTSSDGDMTIRQLQVTRN
. || |||.||.||| || ... ..||||.. .. . ||||||. .|...| ..| .||. ...|.|.|.|.||..
IatqgPlpntvedFWrmvweqnvrvIvmltklvelgrekcaqYwplggsltygditvtllseevlddytvrtlevtnl
|
|||||||||
subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 853-1024 | 2.2e-30 | 100.8 | In-house | 2-172 (319) | alignment | ||
Range on Protein: 853-1024
Range on HMM: 2-172/319.0
NTLIPVIHFTDHLQDLHSsgdgHGRSKMTKEFQTLKSLCPDppasQTRSGRTRDNHPKNRYGNNLPLQRNRVIL----DSPDHDYINASQMKGIH--CTF
.| |.| .. ..|. |.| | .. |||..|| .| ...| . .|..|||| | |. .| ||.| .... |||||| . | . |
dteievqeLkerlkalas....tgetllekefkllkeavnd....tfdsaskeenkkknryqnilaydrtrvvlseldgvegsdyinasfidgyqerekf
MTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQNDK-SCAQYWPDANSVQFGSYSVSTLSTSSDGDMTIRQLQVTRNS
. || || .|..||| || ... |..|||.. ... | . .|||..| ...| . | .. |. ||.|.. ..|
iatqaPlentiedfWrmvWeeessivvmltklveklkvklkkywpeenfeeyGrlivtleeeeeledyiirklklnkks
|
|||||||||
subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 855-1026 | 7.3e-29 | 95.5 | In-house | 1-174 (290) | alignment | ||
Range on Protein: 855-1026
Range on HMM: 1-174/290.0
LIPVIHFTDHLQdlhsSGDGHGRSKMTKEFQTLKSlcpDPPASQTRSGRTRDNHPKNRYGNNLPLQRNRVILD----SPD--HDYINASQMKGI--HCTF
|||| .|..... | .|.... ..|..|.| .. | | .|...||. | .. . ||..| .| ..||||. .|| . .
lipvdkfgefva....nghakgnegfrnqfkmlds...gesehtvtvgltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgykekkqy
MTTQMPLPTTVSDFWSMVLNNKPSTIVMLND-KSQNDKSCAQYWPDANSVQFGSYSVSTLSTSSDGDMTIRQLQVTRNSKR
. || |.. |. |||... ..| . |||| . .... . | |||||... ..| .|. |. .. ....|.|.|. ...
iatqgpvsntlvdFWkliwqekvtiivmltniieegkvkCqqYWpdsdtkaygefsikllneetlneyierklevknknsa
|
|||||||||
subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 856-1028 | 2.3e-37 | 123.8 | In-house | 5-184 (298) | alignment | ||
Range on Protein: 856-1028
Range on HMM: 5-184/298.0
IPVIHFTDHLQDLHSSGDGHGRSKMTKEFQTLKSLCPDPPASQTRSGRTRDNHPKNRYGNNLPLQRNRVILDS----PDHDYINASQMKGIHC--TFMTT
| . ... .|| | . .. .....|||.|.| . .. ... .|...|. |||| . ..|. ||.| . . |||||| ... . .|..|
ieaedlkaalqklaavkkkkkltgyalefqrlnsvsseieeeekevarkpenkkkNRyadiialdssRvvLekedadeesdYiNAsflhaykgrnafiat
QMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQNDK-SCAQYWPDANSVQFGSYSVSTLSTSSDGDMTIRQLQVTRNSKRNR
| ||..||.||| || ... .|||||.. . || . .|||| .. ..|. .|| ||. . .|...|.|.|........
qaPltetvedFWrmvteedigtiVmltnleeldktkyhkywPdegketygeitvsllskeefadlivrklkvskkkeeke
|
|||||||||
subfamily_PTPRB_pd | Subfamily PTPRB | 856-1029 | 1.9e-31 | 104.2 | In-house | 7-181 (293) | alignment | ||
Range on Protein: 856-1029
Range on HMM: 7-181/293.0
IPVIHFTDHLQDLHSSGDghgrSKMTKEFQTLKSLCPDPPASqtrSGRTRDNHPKNRYGNNLPLQRNRVIL----DSPDHDYINASQMKGIHC--TFMTT
| . .|..|...... | ....|...||.. | . . .. |. |||| | || . .|| | |... |||||. ..| .. |..|
iklekfeehvkkmkadsd....lrfseeyeelkavgkdqavk...aaelavnraknrytnilpydhsrvkLaalkdesgsDYinanyipgynsprefiat
QMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQNDK-SCAQYWPDA-NSVQFGSYSVSTLSTSSDGDMTIRQLQVTRNSKRNRV
| |||.|| ||| ||...| |.|||| . . | | .|||. ..|..|. .|. ..... | .||.|..........|
qGPlpetvddfWrmvwekkssiivmltqlvekgkvkCeeYWPadeepvlyGdikvtlvaeeeledwvirelkiekekeerkv
|
|||||||||
subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 856-1026 | 2.5e-31 | 103.9 | In-house | 2-172 (318) | alignment | ||
Range on Protein: 856-1026
Range on HMM: 2-172/318.0
IPVIHFTDHLQDLHSsgdgHGRSKMTKEFQTLKSlCPDPpASQTRSgRTRDNHPKNRYGNNLPLQRNRVILD----SPDHDYINASQMKGIH--CTFMTT
|.| .. .|.. |.. .|. ....|.. |. ... .....| . |. |||| | |. .. || |. ... |||||. . | . ... .
isvedleshvrrlre....sGelllseeyerlsr.seet.vtslks.lepvnkaknryanilaydhtrvkLqmlegeegsDyinanyidGyrrkkayiaa
QMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQ-NDKSCAQYWPDANSVQFGSYSVSTLSTSSDGDMTIRQLQVTRNSKR
| ||| |..||| || . . ..|||| .... . ...|||. .| ..|. | .. . .|...|...|||. .
qaPlpetieDfWrmvWeqnsavivmltqeeergkakvhryWPskgsrsygklvvelkeevelsdyvlrefkvtrteee
|
|||||||||
subfamily_PTPRG_pd | Subfamily PTPRG | 856-1023 | 4.9e-29 | 96.0 | In-house | 1-171 (563) | alignment | ||
Range on Protein: 856-1023
Range on HMM: 1-171/563.0
IPVIHFTDHLQDLHSSGDghgrSKMTKEFQTLKSLCPDPpASQTRSGRTRDNHPKNRYGNNLPLQRNRVILDS-PD----HDYINASQMKGIH--CTFMT
.|| .|. |. .||..|| ....||. |.| . . .. . . ..|. |||| | .. .| || | . |. .|||||. ..| . |..
vpvkefakhvaslhadgd....igfseefealqsetisk.dldaehsqkpenkrKnRylnivaydrsRvklsplpgkkkklDYinAnyidGyqkskafia
TQMPLPTTVSDFWSMVLNNKPSTIVMLND-KSQNDKSCAQYWPDANSVQFGSYSVSTLSTSSDGDMTIRQLQVTRN
|| ||..|. ||| |. ... ..|||. . . .. . | .||| .|...|. .| .. |.|.|..
tqgplkdtfddFWrmiWeqnvaiivmitnlvergrrkcdvYWPkdesetygalqvtlieeevlalytvrtlviknl
|
|||||||||
subfamily_Sponge-PTP3_pd | Subfamily Sponge-PTP3 | 858-941 | 8.5e-06 | 19.9 | In-house | 7-83 (95) | alignment | ||
Range on Protein: 858-941
Range on HMM: 7-83/95.0
VIHFTDHLQDLHSSGDghgrSKMTKEFQTLkslCPDPPASQTrSGRTRDNHPKNRYGNNLPLQRNRVILDS-PDHDYINASQMKG
| | |. ..|| | .. .||... |. | | . | ||||. | .| . ||.| . | ||||| . |
vsvfhshvlemhsnsd....qefdnefksi...smtsgapyt.vgsseanipknrflnifpydatrvvlttkrdsdyinacfvdg
|
|||||||||
0040438 | (Phosphotyrosine protein) phosphatases II | 860-1023 | 5.7e-36 | 119.8 | In-house | 4-166 (317) | alignment | ||
Range on Protein: 860-1023
Range on HMM: 4-166/317.0
HFTDHLQDLHSSGDghgrSKMTKEFQTLKSLCPDppasQTRSGRTRDNHPKNRYGNNLPLQRNRVILDSP----DHDYINASQMKGI--HCTFMTTQMPL
.. ..|.||. |. .. .||..| || .| .. .. .|..|||| . ||. ..||.| .. |.|||||| ..| .| || ||
dlllalldllksdf....talleefedllslkld....tysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPl
PTTVSDFWSMVLNNKPSTIVMLNDKSQN-DKSCAQYWPDANSVQFGSYSVSTLSTSSDGDMTIRQLQVTRN
| || ||| || ... ..||||.. .. .. ||||||. .....| ..| .||. ....|.|.|.|. .
pntvedFwrmvweqgvtvivmLteleelgrekcaqYwplgetltygdftvtllseeelagitlrtlevedl
|
|||||||||
subfamily_PTPN6_pd | Subfamily PTPN6 | 862-1028 | 4.4e-31 | 103.0 | In-house | 10-186 (306) | alignment | ||
Range on Protein: 862-1028
Range on HMM: 10-186/306.0
TDHLQDLHSSGDGHGRSKMTKEFQTLKSLCPDPPASQtRSGRTRDNHPKNRYGNNLPLQRNRVIL---DSPDHDYINASQMK----GIHCTFMTTQMPLP
.. ..|. ... ... ...||..|. |. . |. .|. |||| | || .|||| . |..|||||...| | ......|| |.
eqrvselekeeeslekagfeeefeelqqeeakkllsr.kegakpenkeknryknilPfDhtrvilkepsvpgsdyinanyikkevkgsdksyiatqgcle
TTVSDFWSMVLNNKPSTIVMLNDKSQN-DKSCAQYWPDANS-VQFGSYSVSTLSTSSDGDMTIRQLQVTRN--SKRNR
|||||||.||.... |||. . . ||.||||... ..|..||...| .| | ..|.|.|... .|..|
ttvsdFWrmvwqensrvivmttkevErgkekCarYWPdeeekeeyGkisvtnvseksladYilRelsvskkkkkkeer
|
|||||||||
subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 864-1025 | 3.8e-29 | 96.6 | In-house | 6-168 (287) | alignment | ||
Range on Protein: 864-1025
Range on HMM: 6-168/287.0
HLQDLHSSGDGHGRSKMTKEFQTLKSLCPDPpASQTrSGRTRDNHPKNRYGNNLPLQRNRVILDSPDHDYINASQMKGIH--CTFMTTQMPLPTTVSDFW
.. .. .| .|. .. |..|... .. . | . . .|..|||. . |. . .||.| ..|||||. ..| . |. .. |. |. .||
kfgefvakghakgnegfknqftvleqvtqre.devt.hniasqnkdknRltqilvpdnyrvllkgehpdyinavfidgykekkafiiaesPmfntarnfW
SMVLNNKPSTIVMLNDKSQN-DKSCAQYWPDANSVQFGSYSVSTLSTSSDGDMTIRQLQVTRNSK
.. ......|||| .. .| .. | ||||. .|| .| |... |. ....|.|.|....|
kliddrnvtaivmlcqekendeevcyqyWpeeksvvlGeyniellneevnagyierklevknknk
|
|||||||||
subfamily_PTPN9_pd | Subfamily PTPN9 | 866-1025 | 1.5e-25 | 84.9 | In-house | 4-169 (297) | alignment | ||
Range on Protein: 866-1025
Range on HMM: 4-169/297.0
QDLHSSGDGHGRSKMTKEFQTLKSlcpDPPASQTRSGRTRDNHPKNRYGNNLPLQRNRVILDSP----DHDYINASQMKGI--HCTFMTTQMPLPTTVSD
..| . .|.. ..||.. ... |.. . ..| | |||| . | ... || | . |||||. . | . .|..|| ||. ||||
eelvayvkekgkrGlskeyaeirn...epveGtflasklranleknrytdvlcydetrvvlakvdedeasdyinanfvdGykqkkafiatqGplkktvsd
FWSMVLNNKPSTIVMLNDKSQNDK-SCAQYWP--DANSVQFGSYSVSTLSTSSDGDMTIRQLQVTRNSK
|| || ... .||| .. . |.|||| . .| .||..|||.... . | ..|.|.... .
fWrmvWeqevlvivmttrvvergrlkcgqyWpleeessaefgdlsvsnveveeeedykvrvleiknvkt
|
|||||||||
subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 873-1028 | 7.2e-33 | 108.9 | In-house | 16-176 (288) | alignment | ||
Range on Protein: 873-1028
Range on HMM: 16-176/288.0
DGHGRSKMTKEFQTLKSLCPdppASQTRSGRTRDNHPKNRYGNNLPLQRNRVILDS----PDHDYINASQMKGIHC--TFMTTQMPLPTTVSDFWSMVLN
. ..|. ...|...| .| ... || |..|||| | ||. .|| |. .. |||||| ..| . ....|| ||. || ||| .| .
sarnrtgfseeynsLaalek...tksvtagrlavnakknRyrnilpyDekrvklkkleeeagaDYinasyidgekkkkkyiatqgPladtvndfWelvye
NKPSTIVMLNDK-SQNDKSCAQYWPDANS-VQFGSYSVSTLSTSSDGDMTIRQLQVTRNSKRNR
|| ||||||.. .... | .|||||. ...|| | ... .|.. |.| . .. .. .
nktstivmltelveggktkCeeYWPdadkpknyGsvtvtlveskeledfvlrklllekkktele
|
|||||||||
0047943 | (Phosphotyrosine protein) phosphatases II | 874-1022 | 3.2e-38 | 127.1 | In-house | 8-159 (273) | alignment | ||
Range on Protein: 874-1022
Range on HMM: 8-159/273.0
GHGRSKMTKEFQTLKSLCPdppASQTRSGRTRDNHPKNRYGNNLPLQRNRVILDSPDHDYINASQMKG--IHCTFMTTQMPLPTTVSDFWSMVLNNKPST
|.... .||..|.||.| .. .. .|. |||| . ||. ..||.|.....|||||| ..| . .|. ||.||| || ||| || ... ..
llgltllleefelllslkp...lltysvallpenkdknrykdilpydhsrvklgdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvweqnvrv
IVMLNDKSQNDK-SCAQYWPDAN---SVQFGSYSVSTLSTSSDGDMTIRQLQVTR
||||.. .... ||||||. . |...| ..| .||. ...|.|.|.|..|.
iVmLtelvelgrekcaqYwpleggelsltygkftvtllseetkddytvrtleltn
|
|||||||||
0043336 | (Phosphotyrosine protein) phosphatases II | 874-1024 | 2.3e-34 | 114.6 | In-house | 16-168 (278) | alignment | ||
Range on Protein: 874-1024
Range on HMM: 16-168/278.0
GHGRSKMTKEFQTLKSLCPdppaSQTRSGRTRDNHPKNRYGNNLPLQRNRVILDSPD----HDYINASQMKGI--HCTFMTTQMPLPTTVSDFWSMVLNN
..... .||..| | . .. .. .|..|||| . ||. ..||.|.. . .|||||| ..| .| || ||| || ||| || ..
lnlktllllefeellsfkl....dtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpetvedFwrmvwel
KPSTIVMLNDKSQND-KSCAQYWPdANSVQFGSYSVSTLSTSSDGDMTIRQLQVTRNS
. .|||||.. .. . |||||| .|...| ..| .|.. ...|.|.|.| ||..
gvttivmLtelvelgrvkcaqYwp.ggsltygdftvtllkeehlddytvrtlevtnlg
|
|||||||||
0039614 | (Phosphotyrosine protein) phosphatases II | 875-1025 | 1.9e-37 | 124.8 | In-house | 29-181 (297) | alignment | ||
Range on Protein: 875-1025
Range on HMM: 29-181/297.0
HGRSKMTKEFQTLKSLCPDppasqTRSGRTRDNHPKNRYGNNLPLQRNRVILDS-----PDHDYINASQMKGIHC---TFMTTQMPLPTTVSDFWSMVLN
..... .||..|.|| || .. .. | .|||| . ||. ..||.| . .|.|||||| ..| .. .| || ||| || ||| || .
nsktllllefeellslkpd.....ysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIatqgPlpetvedFwrmvwe
NKPSTIVMLNDKSQNDKSCAQYWPDANSvQFGSYSVSTLSTSSDGDMTIRQLQVTRNSK
.. ..||||.. ... ||||||. . ..| ..| .|.. ....|.|.| ||.|..
qgvtvivmLtklvelgrkcaqywpeegg.tygdftvtllkvehldgytvrtlevtnnge
|
|||||||||
subfamily_PTPN23_pd | Subfamily PTPN23 | 875-1024 | 2.7e-30 | 100.2 | In-house | 12-166 (288) | alignment | ||
Range on Protein: 875-1024
Range on HMM: 12-166/288.0
HGRSKMTKEFQTLKSLCPDPpASQTRSGRTRDNHPKNRYGNNLPLQRNRVILDSPDHDYINASQMKGIHC---TFMTTQMPLPTTVSDFWSMVLNNKPST
.|.... |.|. |.. | .. . . |||. . || .||| |.. |||||| .|.. .|..|| ||..|..|||.|| ..| |.
dgktaldkkfkeleqkqdke.arkrsiaiaklyseknrsrdilPyDhnRvklrgskDDYinAsfvkdlspgcPdfiatqaPlqstlnDFWlmvyeqkssv
IVMLNDKSQNDK-SCAQYWPDA--NSVQFGSYSVSTLSTSSDGDMTIRQLQVTRNS
|||| .|.. .| ....||| . ..|.|| .||. |. . . . |.|... ..
iVmllskeelgkpkvdrYwPedkgetvkfgdlsvtlksvretethvervlkletld
|
|||||||||
subfamily_PTPN12_pd | Subfamily PTPN12 | 875-1028 | 4.5e-27 | 89.7 | In-house | 5-171 (290) | alignment | ||
Range on Protein: 875-1028
Range on HMM: 5-171/290.0
HGRSKMTKEFQTLKSLCPDPPASQ---TRSGRTRDNHPKNRYGNNLPLQRNRVILD----SPDHDYINASQMKGI--HCTFMTTQMPLPTTVSDFWSMVL
.|. ...||||.||.| |.. | .|.. | |||| . || . .|| | ... |||||. .|| ..... .| |||.|..||| |.
egeeefakefqklkklsekykaekvysteagekeenvkknrykDilPydksrvelskieeeegsdYinanfikgvegkleyiaaqgPLpktlddfWrmiw
NNKPSTIVMLNDKSQNDK-SCAQYWPDA--NSVQFGSYSVSTLSTSS-DGDMTIRQLQVTRNSKRNR
. . . .||. . ..| |..|||. ....||...|.. . | |..||.|.|........
eknveivvmaCrevelgkkkCerYWpeegeeelefgefevtleeekavdddflirtLkveaqkesrk
|
|||||||||
0036941 | (Phosphotyrosine protein) phosphatases II | 876-1022 | 6.2e-37 | 122.9 | In-house | 11-161 (297) | alignment | ||
Range on Protein: 876-1022
Range on HMM: 11-161/297.0
GRSKMTKEFQTLkslCPDPPASQTRSGRTRDNHPKNRYGNNLPLQRNRVILDSPDHDYINASQMKGIH--CTFMTTQMPLPTTVSDFWSMVLNNKPSTIV
..... |||..| .| . .. .. .| .|||| . ||. ..||.||....|||||| ..| . .|. || |||.|| ||| ||.... ..||
flalllkefeel...lpllllgslsvallpenleknRykdilpydhtRVklddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqnvtvIv
MLNDKSQNDK-SCAQYWPDA--NSVQFGSYSVSTLSTSS--DGDMTIRQLQVTR
||.. .... ||||||. .|...| ..| .||... ..|.|.|.|.||
mltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtd
|
|||||||||
0045450 | (Phosphotyrosine protein) phosphatases II | 876-1023 | 1.5e-34 | 115.5 | In-house | 25-188 (307) | alignment | ||
Range on Protein: 876-1023
Range on HMM: 25-188/307.0
GRSKMTKEFQTLKSLCPDPpASQTRSGRTRDNHPKNRYGNNLPLQRNRVILDS-----PDHDYINASQMKG----------IHCTFMTTQMPLPTTVSDF
..... |||..|.|..... ..... |..|||| . ||. ..||.| | .|.|||||| .. . .|. || ||| || ||
fltgllkefekllsvtvfl.lgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydlkrkfIatqgPlpetvedF
WSMVLNNKPSTIVMLNDKSQNDKS-CAQYWPDANSV-QFGSYSVSTLSTSSDGDMTIRQLQVTRN
| |. ... ..||||.. ... ||||||| ... ..| . | .||.. ....|.|.| ||..
wrmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdl
|
|||||||||
subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 876-994 | 7.7e-12 | 39.8 | In-house | 14-133 (307) | alignment | ||
Range on Protein: 876-994
Range on HMM: 14-133/307.0
GRSKMTKEFQTLKSLCPDPPASQTrsgrTRDNHPKNRYGNNLPLQRNRVILDSP--DHDYINASQMkGIH---CTFMTTQMPLPTTVSDFWSMVLNNKPS
| .... ||. | |. . .. . | |||| . ...|... . ||| | . || |. .| || .|. .||.|....|
gvqalvdefrvlakktpegvtvea....fsantdknryqdvkcqdkgrivvkfdglasdyihanyl.giaikpkkficaqgplentqysfwamaiqekve
TIVMLNDKSQNDK-SCAQYWPDANS
...|| . . | | |||| .
svimlckvielakikceqywpleeg
|
|||||||||
subfamily_CG7180_pd | Subfamily CG7180 | 877-1023 | 4e-22 | 73.2 | In-house | 12-164 (296) | alignment | ||
Range on Protein: 877-1023
Range on HMM: 12-164/296.0
RSKMTKEFQTLKSLCPDPPASQTRSGRTRDNHPKNRYGNNLPLQRNRVILDS----PDHDYINASQMKGIH--CTFMTTQMPLPTTVSDFWSMVLNNKPS
| |. |.. . | | . . | .| |||. . .| |||.|.. . |||||. . . .. |..| || .||..| ... |
rrkfrveyklelkltprleigdCagglrkenreknrdvkvvPyDynRvvLekldGeeksdYinavyvdsflkkkeyivteapkketvdefWrlvydeeis
TIVMLNDKSQNDKSCAQYWPDANSVQFGSYSVSTLSTSSDGDMTIRQLQVTRN
..|.| .. . | . .||| |.| | .... . ...||....|..
avvvLtktfdfakmypsywpnkskeqygeifveiveekqyanlkirtfkltkk
|
|||||||||
subfamily_PTPRN_pd | Subfamily PTPRN | 877-1006 | 1.1e-18 | 62.0 | In-house | 28-163 (297) | alignment | ||
Range on Protein: 877-1006
Range on HMM: 28-163/297.0
RSKMTKEFQTLKSLCPDPPASQTrsGRTRDNHPKNRYGNNLPLQRNRVILDS----PDHDYINASQMKGI---HCTFMTTQMPLPTTVSDFWSMVLNNKP
.... ||...|.. .| .... ... .| |||. . || . .|| |.. ..||||||.. . ....|| ||..||.||| || ..
kdrlekewealcayeaepstkev..akaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplastvadfwqmvweqGv
STIVMLNDKSQN-DKSCAQYWPDANSVQFGSYSVSTLS
||.| ... | |..|||| | .. | | .|
vvivnltrleeegvkqckrywpdeGsevyhiyevhlvs
|
|||||||||
subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 877-1026 | 1.7e-15 | 51.4 | In-house | 19-172 (439) | alignment | ||
Range on Protein: 877-1026
Range on HMM: 19-172/439.0
RSKMTKEFQTLKSLCPDPPASQTRSGRTRDnHPKNRYGNNLPLQRNRVIL----DSPDHDYINASQMKGIHC--TFMTTQMPLPTTVSDFWSMVLNNKPS
. ....|....| || . . . | ..|||| . ... ||.| | |||| .|| . ...||.| |. ||| .|...| .
qeifkeifekinstspdyaciaslaaqeyd.qtknrykdvgafdhtrvtlqeipgvphshyinanyikGyyddklyiatqgpkkettddfwrlviekktv
TIVMLNDKSQNDKscaqYWPDANSVQFGSYSVSTLSTSSDGDMTIRQLQVTRNS---KR
||||| . . | ||| . | .| .| . . .|| ..| . ..
tivmltnlvesyk....ywpsdaevcygdiavrvdrnielpnyvirgfkvfnerdttek
|
|||||||||
subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 878-1026 | 1.4e-23 | 78.7 | In-house | 34-181 (319) | alignment | ||
Range on Protein: 878-1026
Range on HMM: 34-181/319.0
SKMTKEFQTLKSLCPdPPASQTRSgRTRDNHPKNRYGNNLPLQRNRVILDSPD----HDYINASQMKGIHC--TFMTTQMPLPTTVSDFWSMVLNNKPST
.|. ||. . | . . | || . .| |||..| |. .|.| |. . |||||| ..| ....| ||. |. ||| |. . . ||
tklevefrracklgv.nladqtfa.nldqnkdknriinilafdknvvklerliGeefsdyinasfvtGyqrkdkyiaaqGPldntladfWrmiweyncst
IVMLNdksqnDKSCAQYWPDANSVQFGSYSVSTLSTSSDGDMTIRQLQVTRNSKR
||.| . |.|||| .. . . |. | . ..|........|
ivllt.....kdkcsqywplkivikeerfkvkvdsveetaeyvvrdielsedgke
|
|||||||||
subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 878-992 | 3.9e-16 | 53.9 | In-house | 6-118 (267) | alignment | ||
Range on Protein: 878-992
Range on HMM: 6-118/267.0
SKMTKEFQTLKSLCPDppASQTRSGRTRDNHPKNRYGNNLPLQRNRVILDSPDHDYINASQMKGIH--CTFMTTQMPLPTTVSDFWSMVLNNKPSTIVML
.. |||. .| . .. |. . .|. .||. .||| . .|||| ...||||| ..| . .|. || || |..||. .. ..| ..||.|
ceiekefelikkisdt..sstisqsiaeknqernrlddnlpyddtrvilrtkeeeyinasyvegyktknafivtqdplkntitdfltvihdqkvpvivll
NDKSqNDKsCAQYWPDA
|. ..||
tkvf.tdn.irlfwPPk
|
|||||||||
subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 878-994 | 2.5e-12 | 41.0 | In-house | 24-147 (305) | alignment | ||
Range on Protein: 878-994
Range on HMM: 24-147/305.0
SKMTKEFQTL-KSLCPDPPASQTRSGRTRD-NHPKNRYGNNLPLQRNRVILDSPD-HDYINASQMKGI---HCTFMTTQMPLPTTVSDFWSMVLNNKPST
|. .||. | | || . .. | . |||| . ... | || | ||| | . . |. .| || |. .|| ||..||
dklreefrglakytrpdmtqvafnanqsadiaitknryqdvpcqdqsavkldkpspsdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkveq
IVMLNDKSQNDK-SCAQYWPDANS
|||| . | |||||| |.
ivmlcktvelgklkcaqywpaaqg
|
|||||||||
subfamily_Ptp69D_pd | Subfamily Ptp69D | 879-1026 | 4.9e-29 | 96.4 | In-house | 23-174 (307) | alignment | ||
Range on Protein: 879-1026
Range on HMM: 23-174/307.0
KMTKEFQTLKSLcpdPPASQTRSGRTRDNHPKNRYGNNLPLQRNRVILDS----PDHDYINASQMKGI--HCTFMTTQMPLPTTVSDFWSMVLNNKPSTI
..||...|.. .|. . .| |||| . . ..||.| | |||||| .|| . .|.. | |. .|. ||| |. . . .|
glakeyekLear...eidkstkvsekkenalknRyedikafDktRvkLkkingkedsdYinasfikgykekkkfiaaqdPveatigDfWRmiaeqevtli
VMLNDKSQNDK-SCAQYWPDANSVQFGSYSVSTLSTSSDGDMTIRQLQVTRNSKR
||| . .. .. ||.|||. . ||.|. | . |... .| .||.|.|... .
vmlsnlteknrkkcakYWpiedevqygdilvklvseekhsdyiiReldvskkkee
|
|||||||||
subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 879-1030 | 1.9e-24 | 81.2 | In-house | 16-172 (281) | alignment | ||
Range on Protein: 879-1030
Range on HMM: 16-172/281.0
KMTKEFQTLKSLCPDPPASQTrsgRTRDNHPKNRYGNNLPLQRNRVIL----DSPDHDYINASQMKGIH--CTFMTTQMPLPTTVSDFWSMVLNNKPSTI
...|...|... | .|. . .. .| |||| | || . .. . |||||. ..|.. ...|| |.|... .|| ||...| |.|
Gfieeyeklaaigvdntatas...kadenvlknrYsnivaYDatrvkvtpneenkntDYinanfvpgykgekeyiatqgPvPaslvafWqmvweqkvsai
VMLNDKSQNDK-SCAQYWPDAN-SVQFGSYSVSTLSTSSDGDMTIRQLQVTRNSKRNRVI
||. . ...| | .|||| | ....| . |....... . |.....|.| .| .
vmvtreieagklkChrYWPddnselkygdvtvkstaeeekatyierkfkleresgetrev
|
|||||||||
subfamily_ptpA1_pd | Subfamily ptpA1 | 879-1000 | 1.4e-19 | 65.1 | In-house | 22-147 (418) | alignment | ||
Range on Protein: 879-1000
Range on HMM: 22-147/418.0
KMTKEFQTLKSLCpdpPASQTRSGRTRDNHPKNRYGNNLPLQRNRVIL----DSPDHDYINASQMKGIHC-TFMTTQMPLPTTVSDFWSMVLNNKPSTIV
|. .||. |. |.| | . | |||| | ||... || | | ||||| . | . |. || ||| |..||| || .|. ||
kikeefrlleesv...gpsetsegdkkhntsknrytnilpvnhtrvqlkkiqdkegsdyinanyidgaypkqfictqgplpntiadfwrmvwenrcriiv
MLNDKSQNDK-SCAQYWPDAN-SVQFGSY
||. .|.| . | .|||. || |
mlsresencrikcdrywpeqiggeqfsiy
|
|||||||||
subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 880-1030 | 1e-43 | 144.6 | In-house | 23-179 (297) | alignment | ||
Range on Protein: 880-1030
Range on HMM: 23-179/297.0
MTKEFQTLKSLCPdpPASQTRSGRTRD---NHPKNRYGNNLPLQRNRVIL----DSPDHDYINASQMKGIHCTFMTTQMPLPTTVSDFWSMVLNNKPSTI
. .. . . ||. |....... . . | .|.|| | || ...||.| |.|| ||.||| .||.. ..||||| ..|| ||| |||....|||
rhtdvfseeflcl..peaniqpqtvaekkvnfeksRYkniLPydssRvkLaivnddpdsDyvnasfvkgnkhrlittqmPmkatvadfWamvldeqvsti
VMLNDKSQNDKSCAQYWPDANSVQFGSYSVSTLSTSSDGDMTIRQLQVTRNS-KRNRVI
|||||....||.||.||.| ...||. || .||.|. . |.|.||... | .||.
vmlnddnerdkkcaryWsdkgvttfGdvsvvllsvsereGfikrelevtkgkakarrvv
|
|||||||||
0046845 | (Phosphotyrosine protein) phosphatases II | 880-1023 | 2.5e-37 | 124.2 | In-house | 2-158 (284) | alignment | ||
Range on Protein: 880-1023
Range on HMM: 2-158/284.0
MTKEFQTLKSLCPDPPaSQTRSGRTRDNHPKNRYGNNLPLQRNRVILDS-----PDHDYINASQMKGI-------HCTFMTTQMPLPTTVSDFWSMVLNN
. .||..| || ... ... .. |. |||| . ||. ..||.|.| .|.|||||| ..| ...|. ||.|||.|| ||| ||...
leeefeellsltvkll.lslsvallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweq
KPSTIVMLNDKSQNDK-SCAQYWPDAN-SVQFGSYSVSTLSTSSDGDMTIRQLQVTRN
. ..||||.. .|.. ||||||. . ....| ..| .||. ..|.|.| |..|..
nvrvIVmltelvengrekcaqYwplegevltygdftvtllseevkddytvrtleltnl
|
|||||||||
DSPc_SM00195 | 880-1025 | 2e-36 | 121.0 | In-house | 2-154 (263) | alignment | |||
Range on Protein: 880-1025
Range on HMM: 2-154/263.0
MTKEFQTLKSLCPDPpasQTRSGRTRDNHPKNRYGNNLPLQRNRVILDSPD----HDYINASQMKG--IHCTFMTTQMPLPTTVSDFWSMVLNNKPSTIV
. .||..|.. .. .|.... |. |||| | || ...||.|.... .|||||. .|| .. ||.|||.||.||| ||...| ..||
lkeefekleestspk...etteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiiv
MLNDKSQ-NDKSCAQYWPDA--NSVQFGSYSVSTLSTSSDG-DMTIRQLQVTRNSK
||.. .. . . |..|||. .. .||..|| . .. .. ....|.|..| . |
mlteeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegk
|
|||||||||
PTPc_SM00194 | 880-1025 | 2e-36 | 121.0 | In-house | 2-154 (263) | alignment | |||
Range on Protein: 880-1025
Range on HMM: 2-154/263.0
MTKEFQTLKSLCPDPpasQTRSGRTRDNHPKNRYGNNLPLQRNRVILDSPD----HDYINASQMKG--IHCTFMTTQMPLPTTVSDFWSMVLNNKPSTIV
. .||..|.. .. .|.... |. |||| | || ...||.|.... .|||||. .|| .. ||.|||.||.||| ||...| ..||
lkeefekleestspk...etteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiiv
MLNDKSQ-NDKSCAQYWPDA--NSVQFGSYSVSTLSTSSDG-DMTIRQLQVTRNSK
||.. .. . . |..|||. .. .||..|| . .. .. ....|.|..| . |
mlteeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegk
|
|||||||||
subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 880-1030 | 1.2e-21 | 71.7 | In-house | 12-170 (287) | alignment | ||
Range on Protein: 880-1030
Range on HMM: 12-170/287.0
MTKEFQTLKSLCpDPPASQTRSGRTRDNHPKNRYGNNLPLQRNRVILD-SPDH--DYINASQMKGIH--CTFMTTQMPLPTTVSDFWSMVLNNKPSTIVM
. ||...|| . . .. . ||||.. ||. .||.| ... ||||| . . . .|...| |...|| ||| .||... .....
vdkevdalkeds.esstatfkaaeelaavkknryadvlPiddtrvllsaegelGsdyinanyvasytddeafiaaqgPiaatvrdfwravletrsasvit
L-NDKSQNDKSCAQYWPDAN-SVQFGSYSVSTLST-SSDGDMTIRQLQVTRNSKRN-RVI
. . . . | .|||. . .. | ||| |. . . ..| |.. |. ||.
mtreveearlkcykywPerevPmrvGGysvvlldydikePeygvralrlidletrearvv
|
|||||||||
subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 880-1024 | 3.3e-21 | 70.3 | In-house | 17-168 (301) | alignment | ||
Range on Protein: 880-1024
Range on HMM: 17-168/301.0
MTKEFQTLKSLCPDppasQTRSGRTRDNHPKNRYGNNLPLQRNRVILDSP------DHDYINASQMKGIH--CTFMTTQMPLPTTVSDFWSMVLNNKPST
. .....||. .. .. | . .|.. ||. |. ... ||.|| ..||||| ..|. |. .| |. |. ||| .....||..
feeqykelkegedk....sctvglseenkalnrfknitvyddnriilkpkpnldlcqreyinasyidgysekkkfiaaqgpmkktlvdfWrliwqekpvs
IVMLNDKSQN-DKSCAQYWPDANSV--QFGSYSVSTLSTSSDGDMTIRQLQVTRNS
|||. .. .. ..| ||||... .|| .| .. |..||||.|. .
ivmvtnlkegtkskceqywpnseaeseefgpftvtlvneqvyPdfvirqlnvkiqd
|
|||||||||
subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 880-1022 | 3.9e-20 | 66.7 | In-house | 29-176 (290) | alignment | ||
Range on Protein: 880-1022
Range on HMM: 29-176/290.0
MTKEFqtLKSLCPDPP-ASQTRSGRTRDN-HPKNRYGNNLPLQRNRVIL-DSPDHDYINASQMKGIHCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLN
..||. |. | | | |. .. |||| . .. |||| | | ||. | .||.. .|. || .| || |.| |||..| ..||||
lakey..leklkpylpvqylerkifdkntefkknrykdvvcndktrvilkdGydGdyvhanyvkGlkamfiltqGalkdtvidiwrmvlqekvaaivmlc
DKSQNDKS-CAQYWPDAN--SVQFGSYSVS-TLSTSSDGDMTIRQLQVTR
. .. |. |.||.|. . . ||...| ..... | .. . | |
eliedGkakceqyypekeGevltfGeitvlcseeddkdaniikktlsvrd
|
|||||||||
subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 880-992 | 5e-06 | 20.4 | In-house | 21-131 (312) | alignment | ||
Range on Protein: 880-992
Range on HMM: 21-131/312.0
MTKEFQTLKSLCPDPPAsqTRSGRTRDnhpKNRYGNNLPLQRNRVILDSPDHDYINASQMKGIH--CTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLND
.|||.... . .| | . .| ||| | .| | | . || | .| |..|| || |.. || ..|. ..|..|
ltkeykavgnivsdsec..taflkfkd...lnrypniqcwdrgrftlagdenfyihanfvkictkperfvctqgplentcthfwqlalslgstsiillcg
KSQ-NDKSCAQYWPDA
. . ||.| |
fvedgsekcakyisdi
|
|||||||||
subfamily_PTPN13_pd | Subfamily PTPN13 | 881-1024 | 2.6e-22 | 74.4 | In-house | 14-161 (273) | alignment | ||
Range on Protein: 881-1024
Range on HMM: 14-161/273.0
TKEFQTLKSLCpdpPASQTRSGRTRDNHPKNRYGNNLPLQRNRVILDSPDHdYINASQMKGI----HCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLN
..||..|. | | ....|....|. |||| | || .. ||.|.. ||||| .| . ... .| |||.||.||| || . | . |.|.
aeefkelrelk...pldtcevgkkkenkdknryrnvlPydetrvklgdegg.yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamvt
-DKSQNDKSCAQYWPDANSVQFGS---YSVSTLSTSSDGDMTIRQLQVTRNS
.| .. | .|||. .. . . |. | . ....|.|.|. .
lekekgkvkchrywPesknkklkvsnrlevellkvqkldgfvvralavkdse
|
|||||||||
subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 885-1012 | 1.1e-10 | 35.7 | In-house | 15-152 (281) | alignment | ||
Range on Protein: 885-1012
Range on HMM: 15-152/281.0
QTLKSLCPDPPASQTRSGRTRDNHPKNRYGNNLPLQRNRVILDS--P---DHDYINASQMKG--IHCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLND
| . | |||. | |||| | |. || | | ||| | .. .. .. || | | .||| |. ... ..|||| .
qefsnlpgdppsdlctvfnqpvnnkknrylnipcldisrvqlkvkmpnknstdyihanyirspflkrgyiltqgpkketradfwrmiwqenttaivmlcq
K-SQNDKSCAQYWPDAN--SVQFGSYSVSTLSTSSDGD
| . ||.|.| .|| .||| .. .
fletnrekcaeyfprnahcclqfdklsvsyedstvnks
|
|||||||||
subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 887-1028 | 9.5e-28 | 92.2 | In-house | 28-178 (305) | alignment | ||
Range on Protein: 887-1028
Range on HMM: 28-178/305.0
LKSLCPDppASQTRSGRTRDNHPKNRYGNNLPLQRNRVILDS----PDHDYINASQMKGIH--CTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLN-DKS
|||. . ... |.. |. |||. .. .|. .|.|| .|.|||||| ..| . .....| ||..||.||| .... |.|||||| .
ykslyee..eesidvgkkeankaknrlkeitlldddriiltekeslddsdyinasyvdgykrkkkyivaqgPlkntvadfWrliveekvstivmltklve
QNDKSCAQYWPDANSV--QFGSYSVSTLSTSSDGDMTIRQLQVTR--NSKRNR
.... | ||||.. . .||..|| |... | ..|.|... ..| .|
ggkdkCrqYWpesktekkefgefsvelksektasdyieRklkisiededkesr
|
|||||||||
subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 891-1025 | 3.8e-28 | 93.5 | In-house | 33-174 (325) | alignment | ||
Range on Protein: 891-1025
Range on HMM: 33-174/325.0
CPDPPASQTRSGrTRDNHPKNRYGNNLPLQRNRVIL----DSPDHDYINASQMKGIH--CTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQNDKS
.| . ... .. .| |||. | ..|...||.| |.|. |||||| .. .|...|.||..|. |.| .||. . | .|.|| .....
psddgiakkvam.kpenkaknrfknvvaldksrvvletkkddpssdyinasylrddkkkdvflaaqaPltatindlWrlvldWrcsvvvvlneldlgkdr
CAQYWPDA--NSVQFGSYSVSTLSTSSDGDMTIRQLQVTRNSK
||.|||. .|..||. |. . | |.|.| . .|
cavywpkemgksktfGglevklrtieeisdyvhrvldvkqvkk
|
|||||||||
subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 892-1028 | 2e-65 | 215.7 | In-house | 29-173 (315) | alignment | ||
Range on Protein: 892-1028
Range on HMM: 29-173/315.0
PDPPASQTRSGRTRDNHPKNRYGNNLPLQRNRVIL----DSPDHDYINASQMKGIHC--TFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQNDK-S
|||.....|..|...|..||||.|.|||...||.| ||||.||||||..|.... .....|.||...|.|||.|||..|..||||...|...|| .
pdPdiyrqrvaretinfkknryknilPldsarvkleviddsPdsdyinasyiksvdddkayiasqgPlkasvddfwrmvlqekvttivmvtkkqegdkik
CAQYWPD--ANSVQFGSYSVSTLSTSSDGDMTIRQLqVTRNSKRNR
|.||||| |.||.|||..|..||...|.|...|.| |||.|. |
crqywPdrkadsvefGsikvellsleadtdgvarkl.vtrkseesr
|
|||||||||
subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 892-995 | 4.9e-34 | 112.4 | In-house | 30-148 (392) | alignment | ||
Range on Protein: 892-995
Range on HMM: 30-148/392.0
PDPPASQTRSGRTRDNHPKNRYGNNLPLQRNRVIL----DSPDHDYINASQMKGIHC--TFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLND-----KSQ
|.|.......... .| .||||.|.||....||.| |.||.||.|||....... .....|.| .....|||.||......||.|... | .
pgpdiypqtvaqkeinlkknryknilpydsarvkleviddipdsdylnasyipsfdnekayiasqgpnaaslddfwrmvfqenvttiamvtklkegdkgd
NDKSCAQY----WPDANSV
.....||. |||..
dartvaqfhftewPdkdvp
|
|||||||||
0045098 | (Phosphotyrosine protein) phosphatases II | 892-1022 | 1.1e-31 | 105.7 | In-house | 18-143 (278) | alignment | ||
Range on Protein: 892-1022
Range on HMM: 18-143/278.0
PDPPASQTRSGRTRDNHPKNRYGNNLPLQRNRVIldspdhDYINASQMKGIHCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQN-DKSCAQYWP
. .. |. . ..| .|||| . ||. ..||. |||||| ..| . .| || |||.||.||| |. ... ..||||.. .. . ||||||
llgipseitpalylgnldknRykdilpydhsrVk......dYINAsyidgypkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaqywp
DANSVQFGSYSVSTLSTSSDGDMTIRQLQVTR
. .|...| ..| .||.. .|.|.| | ||
eggsltygdftvtllseevlddytlrtllvtn
|
|||||||||
subfamily_PTPRD_pd | Subfamily PTPRD | 895-1026 | 8.5e-32 | 105.5 | In-house | 36-173 (564) | alignment | ||
Range on Protein: 895-1026
Range on HMM: 36-173/564.0
PASQTRSGRTRDNHPKNRYGNNLPLQRNRVIL----DSPDHDYINASQMKGIH--CTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQNDK-SCAQ
. ..... . | .|||| | .. ..||.| .. |||||| ..| . ... || ||..|..||| || ... ||||||. . ..| |..
qqftweaankpaNkaKNRyanivaYdhsRVvLskvegdegsDYINAsfidgyrkrkayIAtqgPlaetiedFWRmvweqnsstiVmltkleEkgkvkchk
YWPDANSVQFGSYSVSTLSTSSDGDMTIRQLQVtRNSKR
|||. .. ..|.. |. .. |..||.... ...|.
YWPekgtetygeltVtleeeeeladyeirtfkl.kkkks
|
|||||||||
subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 895-1029 | 1.2e-25 | 84.9 | In-house | 21-162 (283) | alignment | ||
Range on Protein: 895-1029
Range on HMM: 21-162/283.0
PASQTRSGRTRDNHPKNRYGNNLPLQRNRVILDSPDHDYINASQMK-----GIHCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKS-QNDKSCAQY
| .. ...|..|||. . .| ...|| |.| .|||||. . .. .| || || ||| || ..| ..|||| .... |.||
pdldadiasadenkrknrnqeivpadqwrvelksesrdyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekitaivmltklqedlrikCsqy
WPDANSVQFGSYSVSTLSTSSDGDMTIRQLQVTRN-SKRNRV
|| |...| . |. . ..|..| . | | .. .
WPkrGsedyGeftvtlrkettsnsfiikelllrvnssakstl
|
|||||||||
subfamily_PTPN3_pd | Subfamily PTPN3 | 895-1029 | 2.5e-25 | 84.0 | In-house | 29-172 (280) | alignment | ||
Range on Protein: 895-1029
Range on HMM: 29-172/280.0
PASQTRSGRTRDNHPKNRYGNNLPLQRNRVILDSPDHDYINASQMK------GIHCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQNDK-SCAQ
| .. | .| .|||| . || ||.|.. . |||||. .. |. ...|| ||..|..||| || ..| |.|||| . .. . | |
pglaisaarkpenlsknryrdilpydatrvklkesetdyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqksslivmlttlverGrvkChq
YWPDA-NSVQFGSYSVSTLSTSSDGDMTIRQLQVTRNS-KRNRV
|||. .....|..|| ..... . .|.| ..... |..|
yWPetedeleygefsvkcekedetksyvlrelvlkdketkeerk
|
|||||||||
subfamily_eak_pd | Subfamily eak | 895-1029 | 4.5e-10 | 33.4 | In-house | 40-181 (332) | alignment | ||
Range on Protein: 895-1029
Range on HMM: 40-181/332.0
PASQTRSGRTRDNHPKNRYGnNLPLQRNRVILDSPD---HDYINASQMK--GIHCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQND-KSCAQY
.. . .. .. .| .. .| .|. | | | ||||| .. . .. | .. . | || |||..| .||.| .. ... . .|
rllsisetarleavnrnvvk.ivpydrylvrltssqlnrlGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledvelkleksdky
WPDAN--SVQFGSYSVSTLSTSSDGDMTIRQLQVTRNSKRNRV
.|| ..|| . | . . . . |.|.... . ||
fpdktreelkfGildverkefvkrniletrllelskGnethrv
|
|||||||||
subfamily_PTPN14_pd | Subfamily PTPN14 | 896-1028 | 2.6e-20 | 67.6 | In-house | 38-183 (300) | alignment | ||
Range on Protein: 896-1028
Range on HMM: 38-183/300.0
ASQTRSGRTRDNHPKNRYGNNLPLQRNRVILDSP---DHDYINASQMK----GIHCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQNDK-SCAQ
... ... .| .|||. . || . ||| | . ...|||||..| | . .....| ||..|| ||| || ... . |||| .. .. | . .
dallstaklpenaeknrfkdvlPyednrvelsptkenstgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivmlteeeedgkeksfk
YWPDA----NSVQFGSYSVSTLSTSSDGDMTIRQLQVTR-NSKRNR
|.|. ..|.|| . |.| ... . .. ..|.. ||..|
yfPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeer
|
|||||||||
subfamily_PTPRA_pd | Subfamily PTPRA | 897-1025 | 4.4e-26 | 86.5 | In-house | 48-183 (330) | alignment | ||
Range on Protein: 897-1025
Range on HMM: 48-183/330.0
SQTRSGRTRDNHPKNRYGNNLPLQRNRVILD----SPDHDYINASQMKGIH--CTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLND-KSQNDKSCAQYW
. .|. |||. | || . .|||| .. |||||| ..| . .|...| |. || ||| |. . | .||||| . | .... |||||
atlelaskeenkeknrvvnilPydfsrvilsvkeGveesdyinasfidGykekdkfiaaqGPkeetvedfwrmiweqksativmltelkerkeekcaqyw
PDANSVQFGSYSVSTLSTSSDGDMTIRQLQVTRNSK
|| .| .| |. . |.|.|.. |.. ..
PdeGlvtyGnirvevedetvlvdytvrkflvqqlpd
|
|||||||||
subfamily_PTPN1_pd | Subfamily PTPN1 | 898-1022 | 2.4e-23 | 77.3 | In-house | 23-155 (290) | alignment | ||
Range on Protein: 898-1022
Range on HMM: 23-155/290.0
QTRSGRTRDNHPKNRYGNNLPLQRNRVILDSPDHDYINAS--QMKGIHCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQ-NDKSCAQYWPDA--
.||. .. |...||| . | . |..|.. | |||||| ... .. .. || ||| ||. || || ..| ..|||| . . ||||||
ptreaklpenrnlnryrdvspydhsrikleradndyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvvekeqikcaqywPqgee
-NSVQFG--SYSVSTLSTSSDGDMTIRQLQVTR
..... ...| .|. . |.|.|...
ekellledtklkvkliseerksyytvrllelen
|
|||||||||
subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 900-1028 | 2.6e-25 | 84.0 | In-house | 42-176 (315) | alignment | ||
Range on Protein: 900-1028
Range on HMM: 42-176/315.0
RSGRTRDNHPKNRYGNNLPLQRNRVIL----DSPDHDYINASQMKGIH--CTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQNDKSCAQ-YWPDA
. . |. |||| | .. . || | |. ||.||. ..| ....| |....| ||| .| ... ..||||.. ...|. |. ||||
dvakkienkqknryiniiaydksrvqlpllendphsdyvnanfidGynkkrryiaaqgpnvasvkdfwrlvfeedigkivmltnlvegekrkaekywpdk
nSVQFGSYSVSTLSTSSDGDMTIRQLQVTRNSKRNR
| .| ..|. | ..|.| | |. ... .
.kviyGkitvtrkseevnteytvrtlsvvfgdnire
|
|||||||||
subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 901-992 | 1.9e-12 | 41.5 | In-house | 42-137 (305) | alignment | ||
Range on Protein: 901-992
Range on HMM: 42-137/305.0
SGRTRDNHPKNRYGNNLPLQRNRVILDSP-DHDYINASQMKG--IHCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVML-NDKSQNDKSCAQYWPDA
. . ... |||| . |..||| |..| |.|| | . |. || || | .||| | |..| .| || | . . | |..|..
afkeaqeagknrykdvgcldnnrvklegpwpheyihanyvstptnpkrfictqaplektcadfwymclqdkveaifmlcnllekgakkcleyfask
|
|||||||||
subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 902-1030 | 6.7e-32 | 105.6 | In-house | 4-138 (250) | alignment | ||
Range on Protein: 902-1030
Range on HMM: 4-138/250.0
GRTRDNHPKNRYGNNLPLQRNRVILDSPD----HDYINASQMKGIHC--TFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQNDKSCAQYWPDANSV
.. .|. |||| . ..|. ||.| . . |||||| ..| . .|..|| ||..|. ||| |||..| .|||||.. ....| . |||| ..
akkpqnkeknryadiialdssrvvLekekgdkesdyinasflhgyderkafiatqgPlqatiedfWrmvleeksgtivmLtnLkesektyhqywPvekae
QFGSYSVSTLSTSSDGDMTIRQLQVTRNSKRNRVI
..|. || ||. .|.|.|.|......| ...|
kyGdvtvsllskeefadytkrklklskakkaderi
|
|||||||||
subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 902-1026 | 6.5e-23 | 76.6 | In-house | 20-145 (284) | alignment | ||
Range on Protein: 902-1026
Range on HMM: 20-145/284.0
GRTRDNHPKNRYGNNLPLQRNRVILDSPD----HDYINASQMKGIHC--TFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNdksqnDKSCAQYWPDANSV
.| |||.|. |. .|.| |. . |||||| ..| ...|| ||. |. ||| |. . . ||||.| .. |.|||| .
anldqnkdknrighilafdknvvklerliGeefsdyinasfitGyqrkdkyiatqGPldntladfWrmiweyncstivllt.....kdkcsqywplkivi
QFGSYSVSTLSTSSDGDMTIRQLQVTRNSKR
. . . |. | . ....|........|
keerfkvkvdsveeseeyvvrdielsedgke
|
|||||||||
0040439 | (Phosphotyrosine protein) phosphatases II | 903-1023 | 4.3e-30 | 100.5 | In-house | 7-134 (249) | alignment | ||
Range on Protein: 903-1023
Range on HMM: 7-134/249.0
RTRDNHPKNRYGNNLPLQRNRVILDS----PDHDYINASQMKG--IHCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQN-DKSCAQYWPDANSV
. |..|||| . ||. ..||.| . ...|||||| ..| | .| || ||| ||.||| |. ... ..||||.. .. . ||||||. .|.
llpenkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywplggsl
QFGSYSVSTLSTSSDGDMTIRQLQVTRN
..| ..| .||. . .|.|.|.|..|..
eygdftvtllsvevkddytvrtleltnl
|
|||||||||
0042113 | (Phosphotyrosine protein) phosphatases II | 903-1023 | 4.5e-29 | 97.0 | In-house | 5-132 (245) | alignment | ||
Range on Protein: 903-1023
Range on HMM: 5-132/245.0
RTRDNHPKNRYGNNLPLQRNRVILDSPD----HDYINASQMKGI--HCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQNDK-SCAQYWPDANSV
. |..|||| . ||. ..||.| ... .|||||| ..| .| || ||| || ||| |. ... .|||||.. ... ||||||. .|.
llpenkdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywplgesl
QFGSYSVSTLSTSSDGDMTIRQLQVTRN
..| ..| .||. ...|.|.|.|.||..
tygdftvtllseehlddytvrtlevtnl
|
|||||||||
subfamily_PTPRK_pd | Subfamily PTPRK | 903-1026 | 9.5e-27 | 88.6 | In-house | 39-168 (314) | alignment | ||
Range on Protein: 903-1026
Range on HMM: 39-168/314.0
RTRDNHPKNRYGNNLPLQRNRVILDSPDHD----YINASQMKGIHC--TFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQND-KSCAQYWPDANSV
. .|. |||.|. |. | ||.| . | | ||||. . . . |. || ||. || ||| .|.... ..||||.. .. | .|||. .|
kkdenreknrsgdilaydrsrvflitidgdpssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasivmltelvevgrvkClkyWPedtev
qFGSYSVSTLSTSSDGDMTIRQLQVTRNSKR
.| | ..|. . .. .| ..|.. ..
.ygdikvelvetellaelvvrifrveklarg
|
|||||||||
subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 903-1019 | 8.1e-14 | 46.4 | In-house | 4-127 (239) | alignment | ||
Range on Protein: 903-1019
Range on HMM: 4-127/239.0
RTRDNHPKNRYGNNLPLQRNRVILD----SPDHDYINASQMK---GIHCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQ-NDKSCAQYWPDANS
. | |. |||| | . ...||.|. | |||||| .. | ....|| . .. ||| |. ... |||| . | | |||||. |
kkrvnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdsts
vQFGSYSVSTLSTSSDGDMTIRQLQ
.. |. | | || .
.kycnlrvtlrktevfadyiirtfv
|
|||||||||
subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 903-1020 | 8.9e-14 | 46.2 | In-house | 3-127 (239) | alignment | ||
Range on Protein: 903-1020
Range on HMM: 3-127/239.0
RTRDNHPKNRYGNNLPLQRNRVILD----SPDHDYINASQMK---GIHCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQ-NDKSCAQYWPDANS
. | |. |||| | . ...||.|. | |||||| .. | ....|| . .. ||| |. ... |||| . | | |||||. |
kkrvnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdsts
vQFGSYSVSTLSTSSDGDMTIRQLQV
.. |. | | || . .
.kycnlrvtlrktevfadyiirtfvm
|
|||||||||
0049772 | (Phosphotyrosine protein) phosphatases II | 903-982 | 2.7e-13 | 45.8 | In-house | 42-155 (314) | alignment | ||
Range on Protein: 903-982
Range on HMM: 42-155/314.0
RTRDNHPKNRYGNNLPLQrNRVILDS---PDHDYINASQMKGIhCTFMTTQMPLPTTVSDF----------WSMVL--NNKPSTIVM-------------
. |. |||| . || |||||.. ..|||||| ..|. ..|. || ||. || || |.||| ... .|||
dlflnrdknryldilpad.nrvilpglpvsgsdyinasyvdgf.lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivmsrdevladelsrL
--------LNDKSQND
|.. . |
daAlgKtpllildgng
|
|||||||||
0037934 | (Phosphotyrosine protein) phosphatases II | 905-1022 | 3.6e-28 | 94.2 | In-house | 8-125 (243) | alignment | ||
Range on Protein: 905-1022
Range on HMM: 8-125/243.0
RDNHPKNRYGNNLPLQRNRVILdsPDHDYINASQMKGIHcTFMTTQMPLPTTVSD----FWSMVLNNKPSTIVMLNDKS-QNDKSCAQYWPdaNSVQFGS
|..|||| . ||. ..||.| ...|||||. ... .. ||.||| || | || |. ... ..||||.. . . |||||| ..|..|
penlsknrysdilpydhsrvkl..egsdyinanliyvtp.rliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywp..gevtygd
YSVSTLSTSSDGDMTIRQLQVTR
..| .||... .|.|.| |....
ftvtllseehlddytvrtlllen
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 905-1024 | 4.7e-15 | 50.2 | In-house | 31-161 (297) | alignment | ||
Range on Protein: 905-1024
Range on HMM: 31-161/297.0
RDNHPKNRYGNNLPLQRNRVILD--SPDHDYINASQMK----GIHCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQND-KSCAQYWPDAN--SV
|||| . | . .|| | ...||||| . .. .| || .|| ||| .| .. .|||. .. . || |||...
nsslrknryrdilatddtrvkllrviterdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrdkcapywpsvvqerl
QFGSYSVSTLSTSSDG--DMTIRQLQVTRNS
. |.. | ||. || . . .||. |
kagdvvveflsstsdefdrviltelqliyrs
|
|||||||||
subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 905-983 | 2e-07 | 24.9 | In-house | 45-122 (303) | alignment | ||
Range on Protein: 905-983
Range on HMM: 45-122/303.0
RDNHPKNRYGNNLPLQRNRVILDspDHDYINASQMKG-IHCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQNDK
.| |||. . . |. .| | | || || .. . . ||.||. | .||| |....| ...| |. ||
vknmdknrfvdvicldhskvkls..dssyihasyleldsskkailtqlplshtaadfwqmiieqkvkcvlllltdseydk
|
|||||||||
subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 905-992 | 1e-06 | 22.4 | In-house | 49-141 (302) | alignment | ||
Range on Protein: 905-992
Range on HMM: 49-141/302.0
RDNHPKNRYGNNLPLQRNRVILDSPDHDYINASQMKGIHC--TFMTTQMPLPTTV---SDFWSMVLNNKPSTIVMLNDKSQNDKSCAQYWPDA
..| ||. . |. |.|.|. .|.|||... .. . . .|.| ... .|| || ..| ..|.| . . .|. ...|
kknlkknqsedvpildsnlvkleaepdsyvnaskvevPeltrsiilaQlpkvdsedsveeFWrmvfqekivsvvilvgeeelkktlselfpkk
|
|||||||||
subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 906-1028 | 1.1e-22 | 75.5 | In-house | 27-162 (274) | alignment | ||
Range on Protein: 906-1028
Range on HMM: 27-162/274.0
DNHPKNRYGNNLPLQRNRVIL-----DSPDHDYINASQMKGIH---CTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLND-KSQNDKSCAQYWPDANSV-
.. |||| . || .. ||.| ...| .|||| .|| . ... || |||.||.||| |. ... . |||| . | .| . ||.|.|||...
gsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneqkCavyfPdaedye
---QFGSYSVSTLSTSSDGDMTIRQLQVTRNSKRNR
..| .. . .. . | ..|.| . .....
iserygdveikvekiverndysvrklvlkylerers
|
|||||||||
subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 906-1028 | 5.2e-21 | 69.9 | In-house | 2-131 (237) | alignment | ||
Range on Protein: 906-1028
Range on HMM: 2-131/237.0
DNHPKNRYGNNLPLQRNRVILDSP--DHDYINASQMKGIHC---TFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDK-SQNDKSCAQYWPDANS-VQFG
.|. |||||| . .||.| . . |||||. .||. .....| || .. ||| || ..| | |||| .|.. | .|||... .|
enkiknrygnivaydhsrvvlkgagsgsdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpstdqpaayg
SYSVSTLSTSSDGDMTIRQLQVTRNSKRNR
..|| | |.| | .... . .
vltvslkkkeefsdytvrslllskrltlke
|
|||||||||
subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 906-1021 | 4.3e-13 | 43.5 | In-house | 51-172 (310) | alignment | ||
Range on Protein: 906-1021
Range on HMM: 51-172/310.0
DNHPKNRYGNNLPLQRNRVIL---DSPDHDYINASQMKG--IHCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQNDK-SCAQYWPDANS-VQFG
.. |||| . . |. || | | .||| | .| . ||. .| || |. ||| |..... .|..| ... . | ||| .|
kymhknrysdvvcldtsrvklkidksryedyihanyvktnylrstficsqgplqhtiidfwrmifqeraesilllckvgeegrpkcvgywpslgvtetyg
SYSVSTLSTSSDgDMTIRQLQVT
|. || ||. .. | .| ||
cirvtnlsesse.efeicnlavt
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 907-1025 | 1.6e-31 | 104.9 | Pfam-A | 1-128 (235) | alignment | ||
Range on Protein: 907-1025
Range on HMM: 1-128/235.0
NHPKNRYGNNLPLQRNRVIL-DSPD-HDYINASQMKGI--HCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQ-NDKSCAQYWP--DANSVQFGS
|. |||| . || ...|| | .|.. .|||||. .|| . .|. ||.||. |..||| ||...| ..||||.. . ... |||||| . .|...|.
nkkknRykdilpydktrvklkgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesltygd
YSVSTL-STS-SDGDMTIRQLQVTRNSK
..| . ... . ..|.|.|... . .
ikvelkekekedekeytlrklelkkkke
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 907-1025 | 1.6e-31 | 104.9 | In-house | 1-128 (235) | alignment | ||
Range on Protein: 907-1025
Range on HMM: 1-128/235.0
NHPKNRYGNNLPLQRNRVIL-DSPD-HDYINASQMKGI--HCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQ-NDKSCAQYWP--DANSVQFGS
|. |||| . || ...|| | .|.. .|||||. .|| . .|. ||.||. |..||| ||...| ..||||.. . ... |||||| . .|...|.
nkkknRykdilpydktrvklkgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesltygd
YSVSTL-STS-SDGDMTIRQLQVTRNSK
..| . ... . ..|.|.|... . .
ikvelkekekedekeytlrklelkkkke
|
|||||||||
subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 907-1029 | 1e-18 | 62.3 | In-house | 20-154 (270) | alignment | ||
Range on Protein: 907-1029
Range on HMM: 20-154/270.0
NHPKNRYGNNLPLQRNRVILDS----PDHDYINASQMKG---IHCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLND-KSQNDKSCAQYWPDANSV---
.. ||| . || . ||.|.. . |||| ..| ........ |||||...|| |....| ..|||. . . .. | |..||| .
gkklnRyadiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkekvk
-QFGSYSVSTLSTSSDGDMTIRQLQVTRNSKRNRV
..| .| .||.. . ...|.........|.
ledgkikvlalseekeegyiltrlrleekgeerrl
|
|||||||||
subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 907-1003 | 4.4e-15 | 50.4 | In-house | 35-137 (285) | alignment | ||
Range on Protein: 907-1003
Range on HMM: 35-137/285.0
NHPKNRYGNNLPLQRNRVILDSPDHDYINASQMK--G-IHCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQN-DKSCAQYWPDA--NSVQFGSY
| ||| . .. ||.| |.||| || |. | . |..||| ||| |.|||| |. ..| . ..|| . . || |.|. . |.|| |
npdlnryadvrcieetrvvlknhdrdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyypeklgevvkfgky
SVS
..
eit
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 907-1002 | 1.6e-14 | 48.3 | In-house | 28-135 (319) | alignment | ||
Range on Protein: 907-1002
Range on HMM: 28-135/319.0
NHPKNRYGNNLPLQRNRVILDS----PDHDYINASQMKGI---HCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQND-KSCAQYWPDANSV---
..|.|. | .|| ||.|.. . |..|| ..| .. ....|..| . |||| .| ... .|| | | |.. | ||.|.| ..
skdksrvinvvPlPetrvvlqrigdddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlselGikvcaeylPtketldnt
-QFGSYSV
.| . |
slyGdilv
|
|||||||||
0041856 | (Phosphotyrosine protein) phosphatases II | 907-993 | 1.9e-14 | 49.1 | In-house | 1-75 (182) | alignment | ||
Range on Protein: 907-993
Range on HMM: 1-75/182.0
NHPKNRYGNNLPLQRNRvildspDHDYINASQMKGIHCT--FMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNdksqndksCAQYWPDAN
|..|||| . || ..| | |||||. . | . . | || ||. || ||. |. ... .|||.|. . .|||.
nldknrysdilpydhsr......dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt........eelywpell
|
|||||||||
subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 907-998 | 6.4e-07 | 23.7 | In-house | 43-139 (288) | alignment | ||
Range on Protein: 907-998
Range on HMM: 43-139/288.0
NHPKNRYGNNLPLQRNRVILDSPDHDYINASQMKGIHC--TFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQNDK-SCAQYWPDA--NSVQFG
| ..|| | || |. . ||.| . . .. .| || .|. .| |.|.. ||||.. . | |.|.| .....|
nptrdryenlprcditrvklsddpdfyiaanvvssakykrrlicaqaPlngtieelWkmllesdveyivmlcellekGkeksaeyfPsklGekarig
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 908-1030 | 4.9e-16 | 53.4 | In-house | 48-192 (350) | alignment | ||
Range on Protein: 908-1030
Range on HMM: 48-192/350.0
HPKNRYGNNLPLQRNRVILD----S--------PDHDYINASQMK------GIHCTF--MTTQMPLPTTVSDFWSMVLNNKPSTIVMLND-KSQNDKSCA
|||| | || ..||.| | |||||. .| | | . || ||| || ||. ..|.|| |..|.. .| . |
faknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcy
QYWPDANSVQFGSYSVS-TLSTSSDGDMTIRQLQVTRNSKRNRVI
.||.. . .. | .. . |.... .| ... | |
rYWqegsydditvklaskwenimgindsslysadvkkeasdndni
|
|||||||||
subfamily_Sponge-PTP-4_pd | Subfamily Sponge-PTP-4 | 918-1021 | 8.5e-08 | 26.6 | In-house | 4-101 (130) | alignment | ||
Range on Protein: 918-1021
Range on HMM: 4-101/130.0
PLQRNRVIldspDHDYINASQM--KGIHCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQNDkscaQYWPDANSVQFGSYSVSTLSTSSDGDMTI
. . .|. ...||||| . | .. || || | ||| |.|. .|.| ..| .||||.. ... . .| |. |
efevsrlq....gntyinasfvGllgrtaeylltqhpladtsmdfwkmmleryvnvlvvlgsveeed....eywpdsePlewyeediivtltdrdefkni
RQLQVT
. ..
kasnle
|
|||||||||
0046846 | (Phosphotyrosine protein) phosphatases II | 922-996 | 1.1e-09 | 33.9 | In-house | 3-76 (176) | alignment | ||
Range on Protein: 922-996
Range on HMM: 3-76/176.0
NRVILDSPDHDYINASQMKGihCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKS-QNDKSCAQYWPDANSVQ
|.. . .| |||||. . | . . .|| ||| |. ||. |..... ...|.|.. . .|..|||. ...
lrllgldldldyinanlilg..srpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklg
|
|||||||||
subfamily_egg_pd | Subfamily egg | 927-1044 | 4.5e-15 | 50.1 | In-house | 68-187 (307) | alignment | ||
Range on Protein: 927-1044
Range on HMM: 68-187/307.0
DspdhDYINASQMKG--IHCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQNdKSCAQYWPDAN--SVQF--GSYSVSTLSTSSDGD--MTIRQL
| |.| | ..|| . .|. .| || || ||| || ... ||||. . .. . | ||| |. |... ||. . .| | | ... .|
d....dfihanrvkGkpllnefilaqaplkntvddfwrmvfqeevqyivmltsrkes.erceyywpkaesdslvtvpGslrienlkvdskadplfrvtkl
QVTRNSkRNRVILDSPDHDYINASNM
.. .. |. |. |.|..
klvGgd.deerflehwqgdvnnssdv
|
|||||||||
0043147 | (Phosphotyrosine protein) phosphatases II | 929-978 | 9.5e-08 | 27.4 | In-house | 3-54 (172) | alignment | ||
Range on Protein: 929-978
Range on HMM: 3-54/172.0
PDHDYINASQMKGIHCT--FMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDK
...|||||| ... ... | || ||. |..||| |. ... ..||.|..
egsdyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltel
|
|||||||||
subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 929-989 | 1.3e-07 | 25.4 | In-house | 68-129 (347) | alignment | ||
Range on Protein: 929-989
Range on HMM: 68-129/347.0
PDHDYINASQMKG--IHCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDkSQNDKSCAQYW
. . |||||..| . .. || ||| || ||| || | . .| . . ..|.. ..
dvetyinashikfdnaskeyiltqyplpdtvrdfwkmvsvtkvtqvvtife.pikdeaieefa
|
|||||||||
0051082 | (Phosphotyrosine protein) phosphatases II | 930-1021 | 5.2e-08 | 28.1 | In-house | 2-66 (151) | alignment | ||
Range on Protein: 930-1021
Range on HMM: 2-66/151.0
DHDYINASQMKGIhctFMTTQMPLPttvsDFWSMVLNNKPSTIVMLNDKSQNDkSCAQYWPDANsvqfgsysvstlstssdgdMTIRQLQVT
||||.|.. | . ...||. ||. .. ... .|||.|... .. |..|.|... .........
lsdyinfsyvtgg...lyrsggpla....dflellkelgiktivnlrseeerg.ycpeylpelg...................ievlhipil
|
|||||||||
0051429 | (Phosphotyrosine protein) phosphatases II | 931-1024 | 3e-11 | 39.0 | In-house | 4-114 (272) | alignment | ||
Range on Protein: 931-1024
Range on HMM: 4-114/272.0
HDYINASQMKGIhCT------FMTTQMPLPTTVSDFWSMvLNNKPSTIVMLNDKSQND-KSCAQYWP------------DANSVQFGSYSVSTLSTSSDG
.||||. ..| . . ...||| |. ||| . ... .|||.| . . . | .||| .| .. .| ..| .||..
sgyiNardvggy.grvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseelll
DMTIRQLQVTRNS
|...| |..|. .
dyilrellltlll
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 931-993 | 7.3e-10 | 32.7 | In-house | 90-157 (349) | alignment | ||
Range on Protein: 931-993
Range on HMM: 90-157/349.0
HDYINASQMKG----IHCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLN-DKSQNDKSCAQYWPDAN
.||||| .| .. ...||.|||.|| ||. ..|.|. .. || || .. . | .|| . .
ddyinanylkltrisvekkyiatqaPlPstvddfykvillngvklvlsLnddkelslekcdiywqels
|
|||||||||
subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 931-1023 | 7.2e-08 | 26.9 | In-house | 46-153 (290) | alignment | ||
Range on Protein: 931-1023
Range on HMM: 46-153/290.0
HDYINASQMKGI-HCTFMTTQMPLPT-------TVSDFWSMVLNNKPSTIVMLNDKSQNDK-----SCAQYWPDANS--VQFGSYSVSTLSTSSDGDMTI
||| |.... .. || |. |. .|| |. . | .||| . ..... .||.| |.. ..|. .|. | . |. .
ddyiHAnrvtcpnglrliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCakYvpesvgeelkfkgltvkCkskekeddvet
RQLQVTRN
|.| |. .
Relvvkfd
|
|||||||||
0036282 | (Phosphotyrosine protein) phosphatases II | 931-998 | 3.3e-07 | 25.6 | In-house | 2-61 (174) | alignment | ||
Range on Protein: 931-998
Range on HMM: 2-61/174.0
HDYINASQMKGIHCT--FMTTQMPLPttvsdFWSMVLNNKPSTIVMLNDKSQND-KSCAQYWPDansvqfG
.|||||| ... ..| . .| ||. || |. ... .|.|||.. ... | .|||.
sdyinaspldlsyitprliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe......l
|
|||||||||
subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 940-1022 | 7.4e-10 | 33.0 | In-house | 86-173 (301) | alignment | ||
Range on Protein: 940-1022
Range on HMM: 86-173/301.0
KGIHCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQ-NDKSCAQYWPDA--NSVQFGSYSVSTLSTSS--DGDMTIRQLQVTR
.| |..|| ||. | ||| |. . .|||| | . . . |..| | .... | ... . .. . . ... |.|.|.
sGhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkisekldigrfkikiknkelilnkkiskrtleved
|
|||||||||
0049260 | (Phosphotyrosine protein) phosphatases II | 944-1019 | 3.8e-07 | 25.4 | In-house | 9-56 (152) | alignment | ||
Range on Protein: 944-1019
Range on HMM: 9-56/152.0
CTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQNDK-SCAQYWpdansvqfgsysvstlstssdgdmtirqlQ
|. || |.| |..||| |. ... .|||||.. . ..| |.||. |
fefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi.............................q
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 945-1016 | 1.4e-14 | 48.3 | In-house | 237-307 (440) | alignment | ||
Range on Protein: 945-1016
Range on HMM: 237-307/440.0
TFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDksQNDKSCAQYWP-DANSVQFGSYSVSTLSTSSDGDMTIR
.|..||||| .|| ||| .| . . |||.|||. |||.|. ||| .. || || ..| . . .|
afiatqmpldstvldfwrlvhdyristiimlnq..lndktcsiywpvntrsvtfgpftvghkgsenmnrvkvr
|
|||||||||
subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 945-1024 | 1.5e-11 | 38.9 | In-house | 5-87 (198) | alignment | ||
Range on Protein: 945-1024
Range on HMM: 5-87/198.0
TFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQNDK-SCAQYWPDANS--VQFGSYSVSTLSTSSDGDMTIRQLQVTRNS
...|| || |..||| || . |||.|| .| . . ||| ..| ..|| ||.| . .. |.|| | .| |.
ryiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnt
|
|||||||||
subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 945-1024 | 1.6e-11 | 38.8 | In-house | 6-88 (199) | alignment | ||
Range on Protein: 945-1024
Range on HMM: 6-88/199.0
TFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQNDK-SCAQYWPDANS--VQFGSYSVSTLSTSSDGDMTIRQLQVTRNS
...|| || |..||| || . |||.|| .| . . ||| ..| ..|| ||.| . .. |.|| | .| |.
ryiatqhplretmadfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnt
|
|||||||||
subfamily_hpo-7_pd | Subfamily hpo-7 | 954-1023 | 7.8e-06 | 20.0 | In-house | 44-114 (263) | alignment | ||
Range on Protein: 954-1023
Range on HMM: 44-114/263.0
PTTVSDFWSMVLNNKPSTIVMLNDKSQN-DKSCAQYWPDANSVQFGSYSVSTLSTSSDGDMTIRQLQVTRN
|. |.... .|....||| | . . | .|.| . |. .| . |. .. |... .
vqtidkfyqtivqtktevvvmLcDfneegvekcssyfPlekdekqklanvnvcttkvqsdvllktlellst
|
|||||||||
subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 956-1023 | 6.8e-07 | 23.6 | In-house | 40-108 (255) | alignment | ||
Range on Protein: 956-1023
Range on HMM: 40-108/255.0
TVSDFWSMVLNNKPSTIVMLNDKSQ-NDKSCAQYWPDANSVQFGSYSVSTLSTSSDGDMTIRQLQVTRN
|| |. .. .|....||| | . . . | .|.| . |. .| | |. .| |..| .
tvdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdeklkladvnvtttkssadvvlrtleitst
|
|||||||||
0049772 | (Phosphotyrosine protein) phosphatases II | 1012-1079 | 2e-09 | 33.1 | In-house | 35-126 (314) | alignment | ||
Range on Protein: 1012-1079
Range on HMM: 35-126/314.0
DMTIRQLQVTRNSKRNRVI-------------LDSPDHDYINASNMKGVhCTFMTTQMPLPTTVSDF----------WSMVL--NNKPSTIVM
..|| . . .| ..|| . |. ..|||||| ..|. ..|. || ||. || || |.||| ... .|||
eltilvadlflnrdknryldilpadnrvilpglpvsgsdyinasyvdgf.lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivm
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 1013-1086 | 8.4e-07 | 22.9 | In-house | 33-109 (319) | alignment | ||
Range on Protein: 1013-1086
Range on HMM: 33-109/319.0
MTIRQLQVTRNSKRNRVILDSPDHDYINASNMKGV---HCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQN
|. . . . . | | . |..|| ..| .. ....|..| . |||| .| ... .|| | | |..
rvinvvPlPetrvvlqrigdddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlsel
|
|||||||||
subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 1017-1081 | 5.7e-06 | 20.2 | In-house | 60-128 (305) | alignment | ||
Range on Protein: 1017-1081
Range on HMM: 60-128/305.0
QLQVTRNSKRNRVILDSPD-HDYINASNMkGV----HCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLN
. | .. | || | ||| | . |. . |. .| || |. .|| ||..|| ||||
ryqdvpcqdqsavkldkpspsdyihanyv.gcpmipekrficaqgpldqtidefwwmviqnkveqivmlc
|
|||||||||
subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 1020-1080 | 1e-10 | 36.0 | In-house | 43-106 (285) | alignment | ||
Range on Protein: 1020-1080
Range on HMM: 43-106/285.0
VTRNSKRNRVILDSPDHDYINASNMKG---VHCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVML
| . ||.| |.||| || |. . |..||| ||| |.|||| |. ..| . ..||
dvrcieetrvvlknhdrdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlml
|
|||||||||
subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 1021-1083 | 6.5e-07 | 23.2 | In-house | 63-128 (310) | alignment | ||
Range on Protein: 1021-1083
Range on HMM: 63-128/310.0
TRNSKRNRVILD-SPDHDYINASNMKG--VHCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDK
... | .. .| | .||| | .| . ||. .| || |. ||| |..... .|..|
cldtsrvklkidksryedyihanyvktnylrstficsqgplqhtiidfwrmifqeraesilllckv
|
|||||||||
subfamily_ptpA1_pd | Subfamily ptpA1 | 1022-1086 | 5.3e-11 | 36.9 | In-house | 61-126 (418) | alignment | ||
Range on Protein: 1022-1086
Range on HMM: 61-126/418.0
RNSKRNRVILDSPDHDYINASNMKGVHC-TFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQN
. . . | | ||||| . | . |. || ||| |..||| || .|. ||||. .|.|
htrvqlkkiqdkegsdyinanyidgaypkqfictqgplpntiadfwrmvwenrcriivmlsresen
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 1022-1082 | 3.1e-07 | 24.6 | In-house | 45-109 (297) | alignment | ||
Range on Protein: 1022-1082
Range on HMM: 45-109/297.0
RNSKRNRVILDSPDHDYINASNMK----GVHCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLND
...| .. ...||||| . .. .| || .|| ||| .| .. .|||.
tddtrvkllrviterdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvak
|
|||||||||
subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 1024-1082 | 3.5e-09 | 31.1 | In-house | 45-105 (267) | alignment | ||
Range on Protein: 1024-1082
Range on HMM: 45-105/267.0
SKRNRVILDSPDHDYINASNMKGVH--CTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLND
. .|||| ...||||| ..| . .|. || || |..||. .. ..| ..||.|
yddtrvilrtkeeeyinasyvegyktknafivtqdplkntitdfltvihdqkvpvivlltk
|
|||||||||
subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 1025-1088 | 4.1e-28 | 93.1 | In-house | 57-126 (315) | alignment | ||
Range on Protein: 1025-1088
Range on HMM: 57-126/315.0
KRNRVIL----DSPDHDYINASNMKGVHC--TFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQNDK
...||.| ||||.|||||| .|.|.. .....|.||...|.|||.|||..|..||||...|...||
dsarvkleviddsPdsdyinasyiksvdddkayiasqgPlkasvddfwrmvlqekvttivmvtkkqegdk
|
|||||||||
subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 1026-1088 | 4.9e-19 | 63.6 | In-house | 65-131 (297) | alignment | ||
Range on Protein: 1026-1088
Range on HMM: 65-131/297.0
RNRVIL----DSPDHDYINASNMKGVHCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQNDK
..||.| |.|| ||.||| .||.. ..||||| ..|| ||| |||....||||||||....||
ssRvkLaivnddpdsDyvnasfvkgnkhrlittqmPmkatvadfWamvldeqvstivmlnddnerdk
|
|||||||||
0050432 | (Phosphotyrosine protein) phosphatases II | 1026-1087 | 8.3e-19 | 63.5 | In-house | 82-146 (308) | alignment | ||
Range on Protein: 1026-1087
Range on HMM: 82-146/308.0
RNRVILdSPDHDYINASNMKGV----HCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQND
..||.| ....|||||| ..| ..| || |||.|| ||| || ... ..||||.. .|.
hsRVkl.degsdYInAsyvdgyssklprkfIatqgPlpntvedFwrmvweqnvrvIvmLtklveng
|
|||||||||
0047943 | (Phosphotyrosine protein) phosphatases II | 1026-1087 | 4.1e-18 | 61.3 | In-house | 52-115 (273) | alignment | ||
Range on Protein: 1026-1087
Range on HMM: 52-115/273.0
RNRVILDSPDHDYINASNMKG--VHCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQND
..||.|.....|||||| ..| . .|. ||.||| || ||| || ... ..||||.. ...
hsrvklgdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvweqnvrviVmLtelvelg
|
|||||||||
0036941 | (Phosphotyrosine protein) phosphatases II | 1026-1086 | 5.2e-18 | 60.8 | In-house | 53-115 (297) | alignment | ||
Range on Protein: 1026-1086
Range on HMM: 53-115/297.0
RNRVILDSPDHDYINASNMKGVH--CTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQN
..||.||....|||||| ..| . .|. || |||.|| ||| ||.... ..||||.. ..
htRVklddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqnvtvIvmltelvel
|
|||||||||
subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 1026-1088 | 5.3e-18 | 59.6 | In-house | 59-127 (392) | alignment | ||
Range on Protein: 1026-1088
Range on HMM: 59-127/392.0
RNRVIL----DSPDHDYINASNMKGVHC--TFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQNDK
..||.| |.||.||.||| ...... .....|.| .....|||.||......||.|... . ||
sarvkleviddipdsdylnasyipsfdnekayiasqgpnaaslddfwrmvfqenvttiamvtklkegdk
|
|||||||||
0046845 | (Phosphotyrosine protein) phosphatases II | 1026-1087 | 9.4e-18 | 60.0 | In-house | 42-115 (284) | alignment | ||
Range on Protein: 1026-1087
Range on HMM: 42-115/284.0
RNRVILDS-----PDHDYINASNMKGV-------HCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQND
..||.|.| .|.|||||| ..| ...|. ||.|||.|| ||| ||.... ..||||.. .|.
hsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqnvrvIVmltelveng
|
|||||||||
DSPc_SM00195 | 1026-1087 | 2.5e-17 | 58.4 | In-house | 40-107 (263) | alignment | |||
Range on Protein: 1026-1087
Range on HMM: 40-107/263.0
RNRVILDSPD----HDYINASNMKG--VHCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQND
..||.|.... .|||||. .|| .. ||.|||.||.||| ||...| ..||||.. ..|.
htrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeeng
|
|||||||||
PTPc_SM00194 | 1026-1087 | 2.5e-17 | 58.4 | In-house | 40-107 (263) | alignment | |||
Range on Protein: 1026-1087
Range on HMM: 40-107/263.0
RNRVILDSPD----HDYINASNMKG--VHCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQND
..||.|.... .|||||. .|| .. ||.|||.||.||| ||...| ..||||.. ..|.
htrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeeng
|
|||||||||
0051299 | (Phosphotyrosine protein) phosphatases II | 1026-1087 | 3e-17 | 58.5 | In-house | 63-130 (288) | alignment | ||
Range on Protein: 1026-1087
Range on HMM: 63-130/288.0
RNRVILDS----PDHDYINASNMKG--VHCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQND
..||.| . ...|||||| ..| ..|. || |||.||.||| || ... ..||||.. ..
hsRVkLsvldgvegsdYinAsyidgynlkrkfIatqgPlpntvedFWrmvweqnvrvIvmltklvelg
|
|||||||||
subfamily_PTPN23_pd | Subfamily PTPN23 | 1026-1086 | 1.7e-16 | 54.9 | In-house | 57-120 (288) | alignment | ||
Range on Protein: 1026-1086
Range on HMM: 57-120/288.0
RNRVILDSPDHDYINASNMKGVHC---TFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQN
.||| |.. |||||| .|.. .|..|| ||..|..|||.|| ..| |.|||| .|..
hnRvklrgskDDYinAsfvkdlspgcPdfiatqaPlqstlnDFWlmvyeqkssviVmllskeel
|
|||||||||
0039614 | (Phosphotyrosine protein) phosphatases II | 1026-1087 | 1.8e-16 | 55.9 | In-house | 70-139 (297) | alignment | ||
Range on Protein: 1026-1087
Range on HMM: 70-139/297.0
RNRVILDS-----PDHDYINASNMKGVHC---TFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQND
..||.| . .|.|||||| ..| .. .| || ||| || ||| || ... ..||||.. ..
hsrvklkpedgvdldsdYinAsyvdgydlltrkfIatqgPlpetvedFwrmvweqgvtvivmLtklvelg
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 1026-1086 | 5.1e-16 | 54.2 | Pfam-A | 15-79 (235) | alignment | ||
Range on Protein: 1026-1086
Range on HMM: 15-79/235.0
RNRVIL-DSPD-HDYINASNMKGV--HCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQN
..|| | .|.. .|||||. .|| . .|. ||.||. |..||| ||...| ..||||.. ..
ktrvklkgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleek
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 1026-1086 | 5.1e-16 | 54.2 | In-house | 15-79 (235) | alignment | ||
Range on Protein: 1026-1086
Range on HMM: 15-79/235.0
RNRVIL-DSPD-HDYINASNMKGV--HCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQN
..|| | .|.. .|||||. .|| . .|. ||.||. |..||| ||...| ..||||.. ..
ktrvklkgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleek
|
|||||||||
0040438 | (Phosphotyrosine protein) phosphatases II | 1026-1087 | 7.6e-16 | 53.7 | In-house | 57-124 (317) | alignment | ||
Range on Protein: 1026-1087
Range on HMM: 57-124/317.0
RNRVILDS----PDHDYINASNMKGV--HCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQND
..||.| . .|.|||||| ..| .| || ||| || ||| || ... ..||||.. ...
hsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPlpntvedFwrmvweqgvtvivmLteleelg
|
|||||||||
0045098 | (Phosphotyrosine protein) phosphatases II | 1026-1086 | 1.2e-15 | 53.1 | In-house | 47-101 (278) | alignment | ||
Range on Protein: 1026-1086
Range on HMM: 47-101/278.0
RNRVIldspdhDYINASNMKGVHCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQN
..||. |||||| ..| . .| || |||.||.||| |. ... ..||||.. ..
hsrVk......dYINAsyidgypkkfIatqgPlpstvadfwrmlwelgitvivmltelvel
|
|||||||||
0045450 | (Phosphotyrosine protein) phosphatases II | 1026-1087 | 1.8e-15 | 52.9 | In-house | 69-145 (307) | alignment | ||
Range on Protein: 1026-1087
Range on HMM: 69-145/307.0
RNRVILDS-----PDHDYINASNMKG----------VHCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQND
..||.| | .|.|||||| .. . .|. || ||| || ||| |. ... ..||||.. ..
htRVklssldgsledsdYiNAsyvrvpllllldgydlkrkfIatqgPlpetvedFwrmlweqgvtvivmltelvelg
|
|||||||||
0043336 | (Phosphotyrosine protein) phosphatases II | 1026-1087 | 6e-15 | 50.9 | In-house | 59-126 (278) | alignment | ||
Range on Protein: 1026-1087
Range on HMM: 59-126/278.0
RNRVILDSPD----HDYINASNMKGV--HCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQND
..||.|.. . .|||||| ..| .| || ||| || ||| || ... .|||||.. ..
hsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpetvedFwrmvwelgvttivmLtelvelg
|
|||||||||
0040439 | (Phosphotyrosine protein) phosphatases II | 1026-1086 | 3.2e-13 | 45.3 | In-house | 25-91 (249) | alignment | ||
Range on Protein: 1026-1086
Range on HMM: 25-91/249.0
RNRVILDS----PDHDYINASNMKGV--HCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQN
..||.| . ...|||||| ..| .| || ||| ||.||| |. ... ..||||.. ..
hsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvel
|
|||||||||
0037934 | (Phosphotyrosine protein) phosphatases II | 1026-1084 | 7.6e-13 | 44.0 | In-house | 24-83 (243) | alignment | ||
Range on Protein: 1026-1084
Range on HMM: 24-83/243.0
RNRVILdsPDHDYINASNMKGVHcTFMTTQMPLPTTVSD----FWSMVLNNKPSTIVMLNDKS
..||.| ...|||||. .... .. ||.||| || | || |. ... ..||||..
hsrvkl..egsdyinanliyvtp.rliatqgPlpetveddlasfwrmlwelgitvivmltelv
|
|||||||||
0042113 | (Phosphotyrosine protein) phosphatases II | 1026-1087 | 1.9e-12 | 42.6 | In-house | 23-90 (245) | alignment | ||
Range on Protein: 1026-1087
Range on HMM: 23-90/245.0
RNRVILDSPD----HDYINASNMKGV--HCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQND
..||.| ... .|||||| ..| .| || ||| || ||| |. ... .|||||.. ..
htrvklspdggdldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelg
|
|||||||||
subfamily_PTPN1_pd | Subfamily PTPN1 | 1026-1082 | 1.4e-11 | 38.6 | In-house | 46-104 (290) | alignment | ||
Range on Protein: 1026-1082
Range on HMM: 46-104/290.0
RNRVILDSPDHDYINAS--NMKGVHCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLND
|..|.. | |||||| ... .. .. || ||| ||. || || ..| ..||||
hsrikleradndyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnk
|
|||||||||
subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 1026-1082 | 3e-11 | 37.5 | In-house | 70-127 (290) | alignment | ||
Range on Protein: 1026-1082
Range on HMM: 70-127/290.0
RNRVIL-DSPDHDYINASNMKGVHCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLND
. |||| | | ||. | .||.. .|. || .| || |.| |||..| ..|||| .
ktrvilkdGydGdyvhanyvkGlkamfiltqGalkdtvidiwrmvlqekvaaivmlce
|
|||||||||
subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 1026-1087 | 5.2e-11 | 37.1 | In-house | 61-124 (287) | alignment | ||
Range on Protein: 1026-1087
Range on HMM: 61-124/287.0
RNRVILDSPDHDYINASNMKGVH--CTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQND
.||.| ..|||||. ..| . |. .. |. |. .|| .. ......|||| .. .||
nyrvllkgehpdyinavfidgykekkafiiaesPmfntarnfWkliddrnvtaivmlcqekend
|
|||||||||
subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 1026-1082 | 1e-09 | 32.7 | In-house | 47-108 (283) | alignment | ||
Range on Protein: 1026-1082
Range on HMM: 47-108/283.0
RNRVILDSPDHDYINASNMK-----GVHCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLND
..|| |.| .|||||. . .. .| || || ||| || ..| ..||||
qwrvelksesrdyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekitaivmltk
|
|||||||||
subfamily_PTPN13_pd | Subfamily PTPN13 | 1026-1085 | 7.3e-08 | 27.0 | In-house | 51-113 (273) | alignment | ||
Range on Protein: 1026-1085
Range on HMM: 51-113/273.0
RNRVILDSPDHdYINASNMKGV----HCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQ
. ||.|.. ||||| .| . ... .| |||.||.||| || . | . |.|. . .
etrvklgdegg.yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamvtleke
|
|||||||||
subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 1026-1081 | 1.1e-06 | 22.7 | In-house | 62-120 (305) | alignment | ||
Range on Protein: 1026-1081
Range on HMM: 62-120/305.0
RNRVILDSP-DHDYINASNMKG--VHCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLN
.||| |..| |.|| | . |. || || | .||| | |..| .| ||
nnrvklegpwpheyihanyvstptnpkrfictqaplektcadfwymclqdkveaifmlc
|
|||||||||
subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 1027-1087 | 8.5e-14 | 46.5 | In-house | 71-137 (298) | alignment | ||
Range on Protein: 1027-1087
Range on HMM: 71-137/298.0
NRVILDS----PDHDYINASNMKGVHC--TFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQND
||.| . . |||||| ... . .|..|| ||..||.||| || ... .|||||.. . |
sRvvLekedadeesdYiNAsflhaykgrnafiatqaPltetvedFWrmvteedigtiVmltnleeld
|
|||||||||
subfamily_PTPN6_pd | Subfamily PTPN6 | 1027-1083 | 9.2e-11 | 36.3 | In-house | 69-132 (306) | alignment | ||
Range on Protein: 1027-1083
Range on HMM: 69-132/306.0
NRVIL---DSPDHDYINASNMK----GVHCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDK
.|||| . |..|||||. .| | ......|| |.|||||||.||.... |||. .
trvilkepsvpgsdyinanyikkevkgsdksyiatqgclettvsdFWrmvwqensrvivmttke
|
|||||||||
subfamily_PTPN3_pd | Subfamily PTPN3 | 1027-1083 | 7.1e-10 | 33.3 | In-house | 56-118 (280) | alignment | ||
Range on Protein: 1027-1083
Range on HMM: 56-118/280.0
NRVILDSPDHDYINAS--NMK----GVHCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDK
||.|.. . |||||. ||. |. ...|| ||..|..||| || ..| |.|||| .
trvklkesetdyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqksslivmlttl
|
|||||||||
0046846 | (Phosphotyrosine protein) phosphatases II | 1027-1083 | 3.6e-07 | 25.6 | In-house | 3-57 (176) | alignment | ||
Range on Protein: 1027-1083
Range on HMM: 3-57/176.0
NRVILDSPDHDYINASNMKGvhCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDK
|.. . .| |||||. . | . . .|| ||| |. ||. |..... ...|.|..
lrllgldldldyinanlilg..srpiatqgplprtladflemlkelgitavvnltee
|
|||||||||
subfamily_PTPRD_pd | Subfamily PTPRD | 1028-1085 | 1e-12 | 42.5 | In-house | 64-127 (564) | alignment | ||
Range on Protein: 1028-1085
Range on HMM: 64-127/564.0
RVIL----DSPDHDYINASNMKGVH--CTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQ
||.| .. |||||| ..| . ... || ||..|..||| || ... ||||||. .
RVvLskvegdegsDYINAsfidgyrkrkayIAtqgPlaetiedFWRmvweqnsstiVmltkleE
|
|||||||||
subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 1028-1087 | 5.4e-12 | 40.4 | In-house | 25-90 (250) | alignment | ||
Range on Protein: 1028-1087
Range on HMM: 25-90/250.0
RVILDSP----DHDYINASNMKGVHC--TFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQND
||.| . . |||||| ..| . .|..|| ||..|. ||| |||..| .|||||.. ....
rvvLekekgdkesdyinasflhgyderkafiatqgPlqatiedfWrmvleeksgtivmLtnLkese
|
|||||||||
subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 1028-1082 | 6.1e-11 | 36.9 | In-house | 44-106 (274) | alignment | ||
Range on Protein: 1028-1082
Range on HMM: 44-106/274.0
RVIL-----DSPDHDYINASNMKGVH---CTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLND
||.| ...| .|||| .|| . ... || |||.||.||| |. ... . |||| .
rvllesessededssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltk
|
|||||||||
subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 1028-1087 | 5.5e-10 | 33.6 | In-house | 62-129 (290) | alignment | ||
Range on Protein: 1028-1087
Range on HMM: 62-129/290.0
RVILD----SPD--HDYINASNMKG--VHCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQND
|..| .| ..||||. .|| . .. || |.. |. |||... ..| . |||| . ...
ritLrpisghkDCtneyinAcyikgykekkqyiatqgpvsntlvdFWkliwqekvtiivmltniieeg
|
|||||||||
subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 1028-1081 | 5.2e-08 | 27.4 | In-house | 19-77 (237) | alignment | ||
Range on Protein: 1028-1081
Range on HMM: 19-77/237.0
RVILDSP--DHDYINASNMKGVHC---TFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLN
||.| . . |||||. .||. .....| || .. ||| || ..| | ||||
rvvlkgagsgsdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmlt
|
|||||||||
subfamily_PTPRK_pd | Subfamily PTPRK | 1029-1083 | 1e-11 | 39.2 | In-house | 64-120 (314) | alignment | ||
Range on Protein: 1029-1083
Range on HMM: 64-120/314.0
VILDSPDHDYINASNMKGVHC--TFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDK
.| . |. |||||. . . . |. || ||. || ||| .|.... ..||||..
tidgdpssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasivmltel
|
|||||||||
subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 1029-1086 | 1.3e-11 | 39.1 | In-house | 65-128 (319) | alignment | ||
Range on Protein: 1029-1086
Range on HMM: 65-128/319.0
VIL----DSPDHDYINASNMKGVH--CTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQN
|.| .... |||||| . | . |. || || .|..||| || ... |..|||.. ...
vvlseldgvegsdyinasfidgyqerekfiatqaPlentiedfWrmvWeeessivvmltklvek
|
|||||||||
subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 1030-1087 | 1.7e-10 | 35.5 | In-house | 66-129 (325) | alignment | ||
Range on Protein: 1030-1087
Range on HMM: 66-129/325.0
IL----DSPDHDYINASNMKGV--HCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQND
.| |.|. |||||| .. .|...|.||..|. |.| .||. . | .|.|| ...
vletkkddpssdyinasylrddkkkdvflaaqaPltatindlWrlvldWrcsvvvvlneldlgk
|
|||||||||
subfamily_PTPRA_pd | Subfamily PTPRA | 1030-1082 | 4.2e-10 | 34.0 | In-house | 76-134 (330) | alignment | ||
Range on Protein: 1030-1082
Range on HMM: 76-134/330.0
ILD----SPDHDYINASNMKGVH--CTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLND
|| .. |||||| ..| . .|...| |. || ||| |. . | .||||| .
ilsvkeGveesdyinasfidGykekdkfiaaqGPkeetvedfwrmiweqksativmlte
|
|||||||||
subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 1031-1086 | 6.2e-10 | 33.2 | In-house | 65-122 (301) | alignment | ||
Range on Protein: 1031-1086
Range on HMM: 65-122/301.0
LDSPDHDYINASNMKGVH--CTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQN
||. ..||||| ..|. |. .| |. |. ||| .....||..|||. .. ..
ldlcqreyinasyidgysekkkfiaaqgpmkktlvdfWrliwqekpvsivmvtnlkeg
|
|||||||||
subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 1031-1082 | 2.5e-07 | 24.5 | In-house | 66-118 (347) | alignment | ||
Range on Protein: 1031-1082
Range on HMM: 66-118/347.0
LDSPDhDYINASNMKG--VHCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLND
| .. ||||| .| . .. || ||| || ||| || | . .| . .
addve.tyinashikfdnaskeyiltqyplpdtvrdfwkmvsvtkvtqvvtife
|
|||||||||
subfamily_PTPRB_pd | Subfamily PTPRB | 1032-1082 | 6.1e-14 | 46.7 | In-house | 75-127 (293) | alignment | ||
Range on Protein: 1032-1082
Range on HMM: 75-127/293.0
DSPDHDYINASNMKGVHC--TFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLND
|... |||||. ..| .. |..|| |||.|| ||| ||...| |.|||| .
desgsDYinanyipgynsprefiatqGPlpetvddfWrmvwekkssiivmltq
|
|||||||||
subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 1032-1088 | 2.6e-11 | 38.0 | In-house | 73-131 (315) | alignment | ||
Range on Protein: 1032-1088
Range on HMM: 73-131/315.0
DSPDHDYINASNMKGVH--CTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQNDK
|. ||.||. ..| ....| |....| ||| .| ... ..||||.. ...|
ndphsdyvnanfidGynkkrryiaaqgpnvasvkdfwrlvfeedigkivmltnlvegek
|
|||||||||
subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 1032-1084 | 3.1e-11 | 37.9 | In-house | 70-124 (318) | alignment | ||
Range on Protein: 1032-1084
Range on HMM: 70-124/318.0
DSPDHDYINASNMKGVH--CTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKS
.... |||||. . | . ... .| ||| |..||| || . . ..|||| ...
geegsDyinanyidGyrrkkayiaaqaPlpetieDfWrmvWeqnsavivmltqee
|
|||||||||
subfamily_PTPN12_pd | Subfamily PTPN12 | 1032-1086 | 8e-11 | 36.3 | In-house | 64-120 (290) | alignment | ||
Range on Protein: 1032-1086
Range on HMM: 64-120/290.0
DSPDHDYINASNMKGVH--CTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQN
.... |||||. .|||. .... .| |||.|..||| |. . . . .||. . .
eeegsdYinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevel
|
|||||||||
subfamily_PTPN9_pd | Subfamily PTPN9 | 1032-1081 | 3.4e-09 | 31.1 | In-house | 66-117 (297) | alignment | ||
Range on Protein: 1032-1081
Range on HMM: 66-117/297.0
DSPDHDYINASNMKGV--HCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLN
. . |||||. . | . .|..|| ||. |||||| || ... .|||
edeasdyinanfvdGykqkkafiatqGplkktvsdfWrmvWeqevlvivmtt
|
|||||||||
0041856 | (Phosphotyrosine protein) phosphatases II | 1032-1082 | 1.5e-07 | 26.7 | In-house | 15-67 (182) | alignment | ||
Range on Protein: 1032-1082
Range on HMM: 15-67/182.0
DSPDHDYINASNMKGVHCT--FMTTQMPLPTTVSDFWSMVLNNKPSTIVMLND
|.| |||||. . | . . | || ||. || ||. |. ... .|||.|..
hsrdldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlte
|
|||||||||
subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 1033-1083 | 5.5e-13 | 43.6 | In-house | 72-124 (288) | alignment | ||
Range on Protein: 1033-1083
Range on HMM: 72-124/288.0
SPDHDYINASNMKGVHC--TFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDK
.. |||||| ..| . ....|| ||. || ||| .| .|| ||||||..
eagaDYinasyidgekkkkkyiatqgPladtvndfWelvyenktstivmltel
|
|||||||||
subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 1033-1086 | 1.1e-12 | 42.8 | In-house | 71-126 (305) | alignment | ||
Range on Protein: 1033-1086
Range on HMM: 71-126/305.0
SPDHDYINASNMKGVH--CTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQN
.|.|||||| ..| . .....| ||..||.||| .... |.|||||| . ..
lddsdyinasyvdgykrkkkyivaqgPlkntvadfWrliveekvstivmltklveg
|
|||||||||
subfamily_Ptp69D_pd | Subfamily Ptp69D | 1033-1086 | 7.6e-11 | 36.7 | In-house | 73-128 (307) | alignment | ||
Range on Protein: 1033-1086
Range on HMM: 73-128/307.0
SPDHDYINASNMKGV--HCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQN
. | |||||| .|| . .|.. | |. .|. ||| |. . . .|||| . ..
kedsdYinasfikgykekkkfiaaqdPveatigDfWRmiaeqevtlivmlsnltek
|
|||||||||
subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 1033-1083 | 5.9e-10 | 33.7 | In-house | 66-118 (281) | alignment | ||
Range on Protein: 1033-1083
Range on HMM: 66-118/281.0
SPDHDYINASNMKGVH--CTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDK
. . |||||. ..|.. ...|| |.|... .|| ||...| |.|||. .
nkntDYinanfvpgykgekeyiatqgPvPaslvafWqmvweqkvsaivmvtre
|
|||||||||
subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 1033-1082 | 1.4e-08 | 29.1 | In-house | 45-97 (270) | alignment | ||
Range on Protein: 1033-1082
Range on HMM: 45-97/270.0
SPDHDYINASNMK---GVHCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLND
. |||| .. | ........ |||||...|| |....| ..|||. .
dsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttg
|
|||||||||
subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 1033-1082 | 4.8e-07 | 23.6 | In-house | 73-124 (439) | alignment | ||
Range on Protein: 1033-1082
Range on HMM: 73-124/439.0
SPDHDYINASNMKGVHC--TFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLND
| |||| .|| . ...||.| |. ||| .|...| .||||| .
vphshyinanyikGyyddklyiatqgpkkettddfwrlviekktvtivmltn
|
|||||||||
subfamily_CG7180_pd | Subfamily CG7180 | 1034-1084 | 5.4e-08 | 26.8 | In-house | 68-120 (296) | alignment | ||
Range on Protein: 1034-1084
Range on HMM: 68-120/296.0
PDHDYINASNMKGV--HCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKS
. |||||. . . . .. |..| || .||..| ... |..|.| ..
eksdYinavyvdsflkkkeyivteapkketvdefWrlvydeeisavvvLtktf
|
|||||||||
0043147 | (Phosphotyrosine protein) phosphatases II | 1034-1082 | 1.6e-07 | 26.7 | In-house | 3-53 (172) | alignment | ||
Range on Protein: 1034-1082
Range on HMM: 3-53/172.0
PDHDYINASNMKGVHCT--FMTTQMPLPTTVSDFWSMVLNNKPSTIVMLND
...||||||........ | || ||. |..||| |. ... ..||.|..
egsdyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnlte
|
|||||||||
subfamily_PTPRG_pd | Subfamily PTPRG | 1035-1086 | 6.8e-11 | 36.1 | In-house | 75-128 (563) | alignment | ||
Range on Protein: 1035-1086
Range on HMM: 75-128/563.0
DHDYINASNMKGVH--CTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQN
..|||||. ..| . |..|| ||..|. ||| |. ... ..|||. . ..
klDYinAnyidGyqkskafiatqgplkdtfddFWrmiWeqnvaiivmitnlver
|
|||||||||
subfamily_PTPN14_pd | Subfamily PTPN14 | 1035-1086 | 3.6e-08 | 27.7 | In-house | 75-130 (300) | alignment | ||
Range on Protein: 1035-1086
Range on HMM: 75-130/300.0
DHDYINASNMK----GVHCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQN
...|||||..| | . .....| ||..|| ||| || ... . |||| .. ..
stgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivmlteeeed
|
|||||||||
subfamily_PTPRN_pd | Subfamily PTPRN | 1035-1086 | 1.1e-06 | 22.7 | In-house | 83-137 (297) | alignment | ||
Range on Protein: 1035-1086
Range on HMM: 83-137/297.0
DHDYINASNMKG---VHCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQN
..|||||| . . ....|| ||..||.||| || .. ||.| ...
ksdyinasaildhdprapayiatqgplastvadfwqmvweqGvvvivnltrleee
|
|||||||||
subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 1036-1082 | 1.4e-09 | 32.8 | In-house | 53-102 (284) | alignment | ||
Range on Protein: 1036-1082
Range on HMM: 53-102/284.0
HDYINASNMKGVHC--TFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLN-D
|||||| ..| ...|| ||. |. ||| |. . . ||||.| |
sdyinasfitGyqrkdkyiatqGPldntladfWrmiweyncstivlltkd
|
|||||||||
subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 1036-1082 | 1.8e-09 | 32.3 | In-house | 89-138 (319) | alignment | ||
Range on Protein: 1036-1082
Range on HMM: 89-138/319.0
HDYINASNMKGVHC--TFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLN-D
|||||| ..| ....| ||. |. ||| |. . . ||||.| |
sdyinasfvtGyqrkdkyiaaqGPldntladfWrmiweyncstivlltkd
|
|||||||||
subfamily_egg_pd | Subfamily egg | 1036-1086 | 2.6e-08 | 27.9 | In-house | 68-120 (307) | alignment | ||
Range on Protein: 1036-1086
Range on HMM: 68-120/307.0
HDYINASNMKG--VHCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQN
|.| | .|| . .|. .| || || ||| || ... ||||. . ..
ddfihanrvkGkpllnefilaqaplkntvddfwrmvfqeevqyivmltsrkes
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 1036-1086 | 4.4e-08 | 27.2 | In-house | 83-141 (350) | alignment | ||
Range on Protein: 1036-1086
Range on HMM: 83-141/350.0
HDYINASNMKGV------HCTF--MTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQN
|||||. .| | . || ||| || ||. ..|.|| |..|... .
nDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvel
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 1036-1086 | 6.3e-08 | 26.3 | In-house | 90-144 (349) | alignment | ||
Range on Protein: 1036-1086
Range on HMM: 90-144/349.0
HDYINASNMK----GVHCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQN
.||||| .| |. ...||.|||.|| ||. ..|.|. .. ||| ..
ddyinanylkltrisvekkyiatqaPlPstvddfykvillngvklvlsLnddkel
|
|||||||||
subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 1036-1081 | 2.4e-07 | 24.8 | In-house | 65-112 (287) | alignment | ||
Range on Protein: 1036-1081
Range on HMM: 65-112/287.0
HDYINASNMKGVH--CTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLN
||||| . . . .|...| |...|| ||| .||... ......
sdyinanyvasytddeafiaaqgPiaatvrdfwravletrsasvitmt
|
|||||||||
0051429 | (Phosphotyrosine protein) phosphatases II | 1036-1084 | 5.8e-06 | 21.7 | In-house | 4-56 (272) | alignment | ||
Range on Protein: 1036-1084
Range on HMM: 4-56/272.0
HDYINASNMKGVhCT------FMTTQMPLPTTVSDFWSMvLNNKPSTIVMLNDKS
.||||. ..| . . ...||| |. ||| . ... .|||.| . .
sgyiNardvggy.grvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrsee
|
|||||||||
subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 1043-1086 | 8.3e-07 | 23.0 | In-house | 84-127 (301) | alignment | ||
Range on Protein: 1043-1086
Range on HMM: 84-127/301.0
NMKGVHCTFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDKSQN
. .| |..|| ||. | ||| |. . .|||| | ..
ptsGhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvek
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 1050-1083 | 2.2e-07 | 24.6 | In-house | 237-270 (440) | alignment | ||
Range on Protein: 1050-1083
Range on HMM: 237-270/440.0
TFMTTQMPLPTTVSDFWSMVLNNKPSTIVMLNDK
.|..||||| .|| ||| .| . . |||.|||.
afiatqmpldstvldfwrlvhdyristiimlnql
|