Gene SpurPTP-sf1-14 in Strongylocentrotus purpuratus

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family PTP
Subfamily SpurPTP-sf1
Protein sequence
ID Type Fasta BLAST phosphatome Note
SpurP091_AA protein Get Run
SpurP091_AA_0-180 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_Urchin-PTP-5_pd Subfamily Urchin-PTP-5 1-185 1e-43 144.6 In-house 99-289 (297) alignment
Range on Protein: 1-185
Range on HMM: 99-289/297.0
MPLSQTVTDFLRLIYDYRISTIVMLNDLSKEDAS-SIYWDEANPNIKQPFSMNVLDTVESEHWTERTLELKHRK--NTRIIQHFQFLSWK--EVDSVDFY
||  .|| || ....|...||||||||....| .   || .   .     |. .| . | |   .|.||... |  ..|... .||..|   .|.  |  
mPmkatvadfWamvldeqvstivmlnddnerdkkcaryWsdkgvttfGdvsvvllsvsereGfikrelevtkgkakarrvvkqyqfveWPdkaverkdsa

QTLLDFMNNVTSQQG--GDSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMaMSQEN
..||.....|  . .   ..|.|||||.|||||||.. .. .. . . |..||.|..|| ||..  ...|  |.||. | ...  . .|.. 
ssllklisevrkdfsqnaegPllvhclaGvGrtgvlltidsvvaeakrekevdifglvkklrqerpylvqtkeqykfvyvavleal.lsedt

DSPc_SM00195 1-179 2.6e-42 140.3 In-house 76-262 (263) alignment
Range on Protein: 1-179
Range on HMM: 76-262/263.0
MPLSQTVTDFLRLIYDYRISTIVMLNDLSKE--DASSIYWDEA--NPNIKQPFSMNVLDTVESE-HWTERTLELKHRK--NTRIIQHFQFLSWKEVDSVD
.||..|| || |.... ....||||.. ...     . || |   ...  . .| .. .. . . ... |||||.. .  .|| ....|. .|.. .  |
gPlpstvedFWrmvweekvkiivmlteeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpd

FYQTLLDFMNNVTSQQGG-DSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLM
  . .|.... |....   ..|..||| .||||||.|......|..|| |. ||.|.|||.||.  ..|.|.|| |. .|... ...
stksvlellravkkskstssgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi

PTPc_SM00194 1-179 2.6e-42 140.3 In-house 76-262 (263) alignment
Range on Protein: 1-179
Range on HMM: 76-262/263.0
MPLSQTVTDFLRLIYDYRISTIVMLNDLSKE--DASSIYWDEA--NPNIKQPFSMNVLDTVESE-HWTERTLELKHRK--NTRIIQHFQFLSWKEVDSVD
.||..|| || |.... ....||||.. ...     . || |   ...  . .| .. .. . . ... |||||.. .  .|| ....|. .|.. .  |
gPlpstvedFWrmvweekvkiivmlteeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpd

FYQTLLDFMNNVTSQQGG-DSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLM
  . .|.... |....   ..|..||| .||||||.|......|..|| |. ||.|.|||.||.  ..|.|.|| |. .|... ...
stksvlellravkkskstssgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi

subfamily_Urchin-PTP-1_pd Subfamily Urchin-PTP-1 1-179 1.3e-37 124.3 In-house 94-277 (315) alignment
Range on Protein: 1-179
Range on HMM: 94-277/315.0
MPLSQTVTDFLRLIYDYRISTIVMLNDLSKEDA--SSIYWDEANPNIK--QPFSMNVLDTVESEHWTERTLELKHRKNTRIIQHFQFLSWKEVDSVDFYQ
.||  .| || |........||||.......|      || . . .      .....|..      . | | ... ...| .  |||  | .  .     
gPlkasvddfwrmvlqekvttivmvtkkqegdkikcrqywPdrkadsvefGsikvellsleadtdgvarklvtrkseesrtvtqfqftewPdkGvdkqts

TLLDFMNNVTSQQGG-DSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLM
.|| .. .| ...|  . ..||||. |||||||.. .. ...|.. ...||||..|| || .  ...|. |.| . | ..   .
sllklikevkadngkkefsllvhcsaGvGrtGvvisidevvaqikrtrsvdvfnfvknlrakrpylvqteeeyafiydavledl

0037934 (Phosphotyrosine protein) phosphatases II 1-178 4.3e-36 120.1 In-house 51-241 (243) alignment
Range on Protein: 1-178
Range on HMM: 51-241/243.0
MPLSQTVTD----FLRLIYDYRISTIVMLNDLS--KEDASSIYWDeaNPNIKQPFSMNVLDTVESEHWTERTLELKH---RKNTRIIQHFQFLSWKEVDS
.||..|| |    |.|......|..||||..|   .      ||   ..    .|. ..|.. . ...| |||.|..    . || ..|...|.| . . 
gPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywp..gevtygdftvtllseehlddytvrtlllenldlddltrlvihyhylpwpdhgv

VDFYQTLLDFMNNVTS---------QQGGDSPVLVHCLNGVGRTGVFCVVKMCLDQLeveDaVDVFQIVKALRHDNFQ-MIQSLEDYKLCYRILNHL
 |  . ||||.. |..         .  ...||||||  ||||||....  ..|..|   . ||....|| ||   .. ..|... |. .|..| .|
PdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtliaaylmllll...g.vdleeavkllreqRpgkavqtpsqyrflyeallel

subfamily_Urchin-PTP-6_pd Subfamily Urchin-PTP-6 1-177 9.4e-36 117.9 In-house 93-274 (515) alignment
Range on Protein: 1-177
Range on HMM: 93-274/515.0
MPLSQTVTDFLRLIYDYRISTIVMLNDLSKEDAS--SIYWDEANPNIK--QPFSMNVLDTVESEHWTERTLELKHRKNTRIIQHFQFLSWKEVDSVDFYQ
.|.  .| || ||.......||.|...|...| .  . || .   .      ...... .      . |.|.. . ...| .  |.|  | .  .    .
gPnkasvddfWrlvlqenvttiamvtklkegdkikcgkyWPdkpgdsvkfGsikvelvsleactggikrkltvlkgddsrtvtqfhfteWPdkGvpkhts

TLLDFMNNVTSQQGG-DSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNH
.|| .. .| ...|    |...||. |||||||.. .. .. . .  ..||||..|. .| .  ...|  |.| . | ..  
sllklikevkadhgqythpliihcsaGvGrtGvvisidsvvahakttrmvdvfnfvtnirqkrpylvqtqeqyafiygavle

subfamily_Urchin-PTP-3_pd Subfamily Urchin-PTP-3 1-182 5.3e-35 116.1 In-house 98-291 (325) alignment
Range on Protein: 1-182
Range on HMM: 98-291/325.0
MPLSQTVTDFLRLIYDYRISTIVMLNDLSKED-ASSIYWDEANPNIKQPFSMNV-LDTV-ESEHWTERTLELKHRKN--TRIIQHFQFLSWKEVDSVDFY
.||..|. |. ||..|.| | .|.|| | ...   ..|| .   . |.  ...| | |. |   .  | |..|  |.  || .. ||. ||...    . 
aPltatindlWrlvldWrcsvvvvlneldlgkdrcavywpkemgksktfGglevklrtieeisdyvhrvldvkqvkkGetrsvkqfqlqswddmGvqkrp

QTLLDF-------MNNVTSQQGGDSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMAMS
 ||. .        . ||..  . .|.|||| .||||||||  .   |...  |  ||.|. || ||.|  .|... . | |.|  |   .  .
atlisilqlvkavservtantkastpilvhcsaGvGrtGvfislysalakvieesrvdifgfvkklrkdrpsmvetvdqyiliyealveaymsg

subfamily_Urchin-PTP-2_pd Subfamily Urchin-PTP-2 1-178 3.5e-34 112.9 In-house 243-437 (440) alignment
Range on Protein: 1-178
Range on HMM: 243-437/440.0
MPLSQTVTDFLRLIYDYRISTIVMLNDLSkEDASSIYWDEANPNI-KQPFSMNVLDTVESEHWTERTLELKHRKNTRIIQHFQFLSWK---EVDSV----
|||  || || ||..|||||||.|||.|  . . ||||      .   ||..    . . .    ||||||....   |. |.  .|    . | |    
mpldstvldfwrlvhdyristiimlnqln.dktcsiywpvntrsvtfgpftvghkgsenmnrvkvrtlelkykeevheirqfevqtwptwiqsdgvqsqe

---DFYQTLLDFMNNVT-------SQQGGDSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHL
   |    |.|.....        |. |   |.||||| |.  .|||| |  ||.||. . |.|||| .. ||    ... .| || |||..| | 
qcmdavlqlmdylrkceiqrsteqsrpgdgppilvhclsgieesgvfctvmncleqlnndgaidvfqnlrllrlsrpnfvptltdyllcykllthh

subfamily_Urchin-PTP-4_pd Subfamily Urchin-PTP-4 1-110 1.7e-08 28.3 In-house 95-166 (392) alignment
Range on Protein: 1-110
Range on HMM: 95-166/392.0
MPLSQTVTDFLRLIYDYRISTIVMLNDLSKEDassiywdeanpnikqpfsmnvldtvesehwtertlelkHRKNTRIIQHFQFLSWKEVDSVDFYQTLLD
.| . .. || |.... ...||.|...| . |                                      . ...| .  |.|  | . |   .  .|| 
gpnaaslddfwrmvfqenvttiamvtklkegd......................................kgddartvaqfhftewPdkdvpkhtssllk

FMNNVTSQQG
|...| .. |
fikevkadfG

0050432 (Phosphotyrosine protein) phosphatases II 2-179 9.8e-48 158.4 In-house 116-299 (308) alignment
Range on Protein: 2-179
Range on HMM: 116-299/308.0
PLSQTVTDFLRLIYDYRISTIVMLNDLSKEDA--SSIYWDEA---NPNIKQPFSMNVLDTVESEHWTERTLELKH--RKNTRIIQHFQFLSWKEVDSVDF
||..|| || |.........||||..|   .      || .    .. .  .|. ..|.. . ...| |||||..   ...|...||....|.. .  . 
PlpntvedFwrmvweqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseevlddytvrtleltnlgdgesrtvthfhytnWpdhgvPps

YQTLLDFMNNVTSQQgGDSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLM
 . ||||.. | ... ...|..||| .||||||.|... ..|.||| |  ||||..|| ||.   .|.|..| |...||.| ...
peilldflelvrksl.pggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylflyralleyl

subfamily_PTPRD_pd Subfamily PTPRD 2-185 3.6e-47 156.2 In-house 99-287 (564) alignment
Range on Protein: 2-185
Range on HMM: 99-287/564.0
PLSQTVTDFLRLIYDYRISTIVMLNDLSKEDA--SSIYWDEANPNIKQPFSMNVLDTVESEHWTERTLEL--KHRKNTRIIQHFQFLSWKEVDSVDFYQT
||..|. || |.......||||||. |. ..    . || | ..   . .  .. ...| .. . ||..|  |.....| ...|.| || . .  .. ..
PlaetiedFWRmvweqnsstiVmltkleEkgkvkchkYWPekgtetygeltVtleeeeeladyeirtfklkkkkssesreVrqFhFtsWPdhgvpesats

LLDFMNNVTSQQG-GDSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMAMSQEN
|||....|.. .  .  |..||| .||||||.|.|....|.... |. ||..|.|||||..   |.|. | |  ....... .|. ...
lLdlirkvralnepdagPivVhCSaGVGRTGtfividamlerikeektvDiyqyvkalrkqRnamVqteeQYiFiheailealacgnte

0051299 (Phosphotyrosine protein) phosphatases II 2-178 3.5e-46 153.3 In-house 100-285 (288) alignment
Range on Protein: 2-178
Range on HMM: 100-285/288.0
PLSQTVTDFLRLIYDYRISTIVMLNDLSKEDA--SSIYWDEANPNIKQPFSMNVLDTVESEHWTERTLELK------HRKNTRIIQHFQFLSWKEVDSVD
||..|| || |.........||||..|   .   .  || . .. .  ... . |.... ...| ||||..        ...|...||....| . .  |
PlpntvedFWrmvweqnvrvIvmltklvelgrekcaqYwplggsltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpd

FYQTLLDFMNNVTSQ-QGGDSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHL
  . ||||.. | .. . |..||.||| .||||||.|... ..|.||| |  |||...|| ||.  ..|.|..| |...|..| ..
spellldflrlvrkalasgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyealley

subfamily_Anemone-PTP-2_pd Subfamily Anemone-PTP-2 2-180 3.2e-45 149.7 In-house 107-291 (298) alignment
Range on Protein: 2-180
Range on HMM: 107-291/298.0
PLSQTVTDFLRLIYDYRISTIVMLNDLSKEDA--SSIYWDEANPNIKQPFSMNVLDTVESEHWTERTLELKHRK--NTRIIQHFQFLSWKEVDSVDFYQT
|| .||.|| |.. .. |.|||||..|   |    . || . . .    .....| . |    . |.|.....|  ..| .....| || . .    ...
PltetvedFWrmvteedigtiVmltnleeldktkyhkywPdegketygeitvsllskeefadlivrklkvskkkeekerevrqlhftsWpdkgvpenats

LLDFMNNVT--SQQGGDSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMA
.||....|    || |..||.|.| .||||.| |....  |.... |  |||||.||.||..  ...|. |.|. .| .  . ..
vldllrkvrasqqqagnkpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavleald

0046845 (Phosphotyrosine protein) phosphatases II 2-179 4.9e-45 149.5 In-house 85-274 (284) alignment
Range on Protein: 2-179
Range on HMM: 85-274/284.0
PLSQTVTDFLRLIYDYRISTIVMLNDLSKED--ASSIYWDEAN-PNIKQPFSMNVLDTVESEHWTERTLELKH---RKNTRIIQHFQFLSWKEVDSVDFY
||..|| || |.........||||..|   .    . || . . . .  .|. ..|.. . ...| |||||..    ...|...||...|| . .  .  
PlpntvedFwrmvweqnvrvIVmltelvengrekcaqYwplegevltygdftvtllseevkddytvrtleltnlgytgesrtvthfhytswpdhgvppsp

QTLLDFMNNVTSQQGG---DSPVLVHCLNGVGRTGVFCVVKMCLDQLEVED---AVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLM
. ||.|.. | ...     ..|..||| .||||||.|... ..|.||| |.    |||...|| ||   ..|.|.|| |...|..| ...
edlleflrlvrellenlpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleyl

subfamily_Sponge-PTP8_pd Subfamily Sponge-PTP8 2-186 5e-45 149.0 In-house 97-290 (305) alignment
Range on Protein: 2-186
Range on HMM: 97-290/305.0
PLSQTVTDFLRLIYDYRISTIVMLNDLSKED--ASSIYWDEANPN--IKQPFSMNVLDTVESEHWTERTLELKH---RKNTRIIQHFQFLSWKEVDSVDF
|| .||.|| |||.....|||||| .| ...      || |.  .    ..||... .. . . ..|| |..      |..| . ..|. .| .   ..|
PlkntvadfWrliveekvstivmltklveggkdkCrqYWpesktekkefgefsvelksektasdyieRklkisiededkesrtvlqyqltdWPdhGvpqf

YQTLLDFMNNVTSQQGGD--SPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMAMSQENT
  .||.....|. .|  |   |.|||| .||||||||..|.. |..|. |. ||||...|.||.   .|.|.|. |  .. .|. |.   . . 
atsllslikrvqkdqkkdkgvpllVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkmvqtldqYvflhdaldelitcgdtsi

Y_phosphatase Protein-tyrosine phosphatase 2-175 1.2e-44 147.9 Pfam-A 50-233 (235) alignment
Range on Protein: 2-175
Range on HMM: 50-233/235.0
PLSQTVTDFLRLIYDYRISTIVMLNDLSKE--DASSIYWD--EANPNIKQPFSMNVL-DTV-ESEHWTERTLELKHRKNT---RIIQHFQFLSWKEVDSV
||..|. || |.........||||..| ..   . . ||.  | ...  . .....  ..  .....| |.||||..|.    |....... .|.. .  
PlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesltygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvp

DFYQTLLDFMNNVTSQQ-GGDSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRIL
. .. |||....| ...   ..||.||| .||||||.|......|.||| |. |||.|||| ||.  ..|.|||| |. .|...
espkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmvqsleqYiflykai

Y_phosphatase Protein-tyrosine phosphatase 2-175 1.2e-44 147.9 In-house 50-233 (235) alignment
Range on Protein: 2-175
Range on HMM: 50-233/235.0
PLSQTVTDFLRLIYDYRISTIVMLNDLSKE--DASSIYWD--EANPNIKQPFSMNVL-DTV-ESEHWTERTLELKHRKNT---RIIQHFQFLSWKEVDSV
||..|. || |.........||||..| ..   . . ||.  | ...  . .....  ..  .....| |.||||..|.    |....... .|.. .  
PlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesltygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvp

DFYQTLLDFMNNVTSQQ-GGDSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRIL
. .. |||....| ...   ..||.||| .||||||.|......|.||| |. |||.|||| ||.  ..|.|||| |. .|...
espkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmvqsleqYiflykai

0047943 (Phosphotyrosine protein) phosphatases II 2-177 2.1e-44 147.4 In-house 85-270 (273) alignment
Range on Protein: 2-177
Range on HMM: 85-270/273.0
PLSQTVTDFLRLIYDYRISTIVMLNDLSKEDA--SSIYWDEAN---PNIKQPFSMNVLDTVESEHWTERTLELKH--RKNTRIIQHFQFLSWKEVDSVDF
||..|| ||.|.........||||..|   .      || . .   . .  .|. ..|.. . ...| |||||..   ...|...||....| . .  . 
PlpntvedfwrmvweqnvrviVmLtelvelgrekcaqYwpleggelsltygkftvtllseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvpps

YQTLLDFMNNVTSQQG---GDSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNH
.. ||.|.. | ...    ...||.||| .||||||.|... ..||||| |  |||...|| ||   . |.|..| |...|..| .
lesllefielvrkalealpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyealle

0036941 (Phosphotyrosine protein) phosphatases II 2-178 3.7e-44 146.6 In-house 86-276 (297) alignment
Range on Protein: 2-178
Range on HMM: 86-276/297.0
PLSQTVTDFLRLIYDYRISTIVMLNDLSKEDA--SSIYWDEA--NPNIKQPFSMNVLDTVE--SEHWTERTLELKH--RKNTRIIQHFQFLSWKEVDSVD
||..|| || |.........||||..|   .      || .   ..    .|....|.. .  ....| ||||...   ...|...||....| . .  .
PlpntvedFWrmvweqnvtvIvmltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpe

FYQTLLDFMNNVTSQQG---GDSPVLVHCLNGVGRTGVFCVVKMCLDQLE---VEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHL
 ...||||.. | ...    ...|||||| .||||.|.|... ..|.|||    |  ||....|| ||.  ....|.|| |. .|..| .|
spaslldfielvrkvlkllpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallel

0039614 (Phosphotyrosine protein) phosphatases II 2-178 1.1e-43 145.2 In-house 109-288 (297) alignment
Range on Protein: 2-178
Range on HMM: 109-288/297.0
PLSQTVTDFLRLIYDYRISTIVMLNDLSKEDA-SSIYWDEANPnIKQPFSMNVLDTVESEHWTERTLELKHRKNTRIIQHFQFLSWKEVDSVDFYQTLLD
||..|| ||.|.........||||..|   .     || |       .|. ..|.. . ...| ||||... . .|...|||...| . .  .  ..||.
PlpetvedFwrmvweqgvtvivmLtklvelgrkcaqywpeegg.tygdftvtllkvehldgytvrtlevtnngesrtvthfqytgwpdhgvppslellle

FMNNVTSQQG---GDSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHL
|.. | ...    .. |||||| .||||||.|..  ..|.||| |  |||...|| ||    ...|... |. .|..| .|
flelvrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydallel

0040438 (Phosphotyrosine protein) phosphatases II 2-179 5.2e-43 142.9 In-house 94-276 (317) alignment
Range on Protein: 2-179
Range on HMM: 94-276/317.0
PLSQTVTDFLRLIYDYRISTIVMLNDLSKED--ASSIYWDEANPNIKQPFSMNVLDTVESEHWTERTLELKH--RKNTRIIQHFQFLSWKEVDSVDFYQT
||..|| ||.|.........||||..|   .   .  || . ..    .|....|...| ...| ||||...   ...|...||....| . .  .  ..
PlpntvedFwrmvweqgvtvivmLteleelgrekcaqYwplgetltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdl

LLDFMNNVTSQQGG-DSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLM
||||.. | ... . ..|||||| .||||||.|... ..|.||| |  |||...|| ||.   ...|..| |. .|..|....
lldfleavrealedpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleyl

subfamily_Urchin-PTPRB-like_pd Subfamily Urchin-PTPRB-like 2-181 4.6e-42 139.0 In-house 98-281 (288) alignment
Range on Protein: 2-181
Range on HMM: 98-281/288.0
PLSQTVTDFLRLIYDYRISTIVMLNDL--SKEDASSIYWDEA-NPNIKQPFSMNVLDTVESEHWTERTLELKHRKNTRIIQHFQFLSWKEVDSVDFYQTL
|| .|| || .|.|....||||||..|    .     || .| .|.    . . .... | |....|.|.|...|. . |...|.|.| . .  .  . |
PladtvndfWelvyenktstivmltelveggktkCeeYWPdadkpknyGsvtvtlveskeledfvlrklllekkkteleitqyqylaWpdhgvPeskapl

LDFMNNVTSQQGGD-SPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMAM
|.....|  ..  |  |..||| .||||||.| .... .|..| || .||. .|. ||.  ....| |. |  .|..| .|.  
lellrqvkvanqadtgpiivhCsaGvGrtgtFialdalidaveeedyiDvagtvaklRkqRallvqtlkqYefiyevllsliee

subfamily_PTPRK_pd Subfamily PTPRK 2-175 9e-42 138.0 In-house 94-273 (314) alignment
Range on Protein: 2-175
Range on HMM: 94-273/314.0
PLSQTVTDFLRLIYDYRISTIVMLNDLSKED--ASSIYWDEANPNiKQPFSMNVLDTVESEHWTERTLELKH----RKNTRIIQHFQFLSWKEVDSVDFY
|| .||.|| ||.||.. ..||||..| ..     . || |      ... .....|   .    |.. ...     ...|....||||.| . |     
PlqetvkdfWrlvydencasivmltelvevgrvkClkyWPedtev.ygdikvelvetellaelvvrifrveklargqeeirevrqfqflgWpdhdvPvsa

QTLLDFMNNVTSQ-QGGDSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRIL
..||... .| .. . .. ...|||..| ||||.|..... || .| |. ||||..||.||     |..  | ||..| ..
tgllklvrrvkksqeeeaGrivvhCsaGaGrtGtfiaidivldmieregvvdvfnavktlrsrkvnmveteeqykfiydvi

0043336 (Phosphotyrosine protein) phosphatases II 2-177 9.4e-42 138.8 In-house 96-275 (278) alignment
Range on Protein: 2-177
Range on HMM: 96-275/278.0
PLSQTVTDFLRLIYDYRISTIVMLNDLSKEDA--SSIYWDeANPNIKQPFSMNVLDTVESEHWTERTLELK--HRKNTRIIQHFQFLSWKEVDSVDFYQT
||..|| || |........|||||..|   .   .  ||   ..    .|. ..|.. . ...| ||||..    ...|...|...|.| . .  .  ..
PlpetvedFwrmvwelgvttivmLtelvelgrvkcaqYwp.ggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsl

LLDFMNNVTSQQG-GDSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNH
||||.. | ...   ..|||||| .||||||.|... ..|.||| |  ||....|| ||.  ....|... |. .|..| .
lldflkavrealedsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyealle

subfamily_Anemone-PTP-5_pd Subfamily Anemone-PTP-5 2-187 3.4e-41 136.4 In-house 99-292 (319) alignment
Range on Protein: 2-187
Range on HMM: 99-292/319.0
PLSQTVTDFLRLIYDYRISTIVMLNDLSKED--ASSIYWDEANPNIKQPFSMNVLDTVESEHWTERTLELKHRKN---TRIIQHFQFLSWKEVDSVDFYQ
||..|. || |.......|..|||..|. .     . ||.|.|..    . .....  | |..  | |.|.....   || ..|||...| . |  .  .
PlentiedfWrmvWeeessivvmltklveklkvklkkywpeenfeeyGrlivtleeeeeledyiirklklnkkssevetRevkhfqyteWpdhdvPekat

TLLDFMNNVTS-QQG-GDSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMAMSQ-ENTL
.|||.....   ...  . |. ||| .|||||| |.|... |.... | ..|||..|. ||     |.|  | ||..| .| . . . . |  .
slldllkrirksrektqsgPivvhCsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyealleaveagdteiev

subfamily_Nvec-PTP-2_pd Subfamily Nvec-PTP-2 2-182 3.4e-41 136.1 In-house 60-245 (250) alignment
Range on Protein: 2-182
Range on HMM: 60-245/250.0
PLSQTVTDFLRLIYDYRISTIVMLNDLSKEDA-SSIYWDEANPNIKQPFSMNVLDTVESEHWTERTLELKHRKNT--RIIQHFQFLSWKEVDSVDFYQTL
||..|. || |..... ..|||||..|. ..   . ||   ....     ...|.. |   .| |.| | ..|..  ||.....|..| .    . ... 
PlqatiedfWrmvleeksgtivmLtnLkesektyhqywPvekaekyGdvtvsllskeefadytkrklklskakkaderivrqlhfvvWPdkgvPevatav

LDFMNNVTS--QQGGDSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMAMS
|.....| .  || |..||.|.| .||||.| |....  |..|. |  ||||...|.||.|  ....||| |  .|.|. . .  .
LellkkvqasqqqagnaPvivqCsaGvgrsGafiaidavlerlkkekvvdvfkvikvlrkdrphavesleqyvfvyeiilkaldsv

0040439 (Phosphotyrosine protein) phosphatases II 2-178 1.1e-40 135.2 In-house 62-245 (249) alignment
Range on Protein: 2-178
Range on HMM: 62-245/249.0
PLSQTVTDFLRLIYDYRISTIVMLNDLSKE--DASSIYWDEANPNIKQPFSMNVLDTVESEHWTERTLELK--HRKNTRIIQHFQFLSWKEVDSVDFYQT
||..|| ||.|......|..||||..|          ||.. ..     |. ..|.. .....| |||||.    ...| ..|.|...| . .  .. ..
PlpetvedfwrmlwelgitvivmLtslvelgrekcaqywplggsleygdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfed

LLDFMNNVTSQQG---GDSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHL
||||.. | . .     ..|||||| .||||||.|..  ..|.||| |  ||....|| ||.  ....|..| |. .|..| .|
lldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdleeavkllrsqRpgavqnpeqyrflyeallel

0045450 (Phosphotyrosine protein) phosphatases II 2-178 1.2e-40 135.5 In-house 115-303 (307) alignment
Range on Protein: 2-178
Range on HMM: 115-303/307.0
PLSQTVTDFLRLIYDYRISTIVMLNDLSKEDA--SSIYWDEA-NPNIKQPFSMNVLDTVESEHWTERTLELK---HRKNTRIIQHFQFLSWKEVDSVDFY
||..|| ||.|.........||||..|   .      || .   .    .| ...|.. . ...| ||||..     ...|...||....| . .  .. 
PlpetvedFwrmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsf

QTLLDFMNNVTSQQG---GDSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDA---VDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHL
..||||.. | . ..   ...||||||  ||||||.|..  ..|.||| |     ||....|| ||    ...|..| |. .|..| .|
eelldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeallel

subfamily_Anemone-PTP-6_pd Subfamily Anemone-PTP-6 2-184 6.1e-40 132.2 In-house 97-285 (318) alignment
Range on Protein: 2-184
Range on HMM: 97-285/318.0
PLSQTVTDFLRLIYDYRISTIVMLNDLSKED--ASSIYWDEANPNIKQPFSMNVLDTVESEHWTERTLELKHRK--NTRIIQHFQFLSWKEVDSVDFYQT
||..|..|| |....   ..|||| ... .       || . ...  .   ... ..||..... |........  ..|... ... || . .. .   .
PlpetieDfWrmvWeqnsavivmltqeeergkakvhryWPskgsrsygklvvelkeevelsdyvlrefkvtrteeeesrqvrqyhytsWpdegvpesgas

LLDFMNNVTSQQ--GGDSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMAMSQE
|||.. .|.. |   | .|..|||  ||||||||..|.. |.... |  |||||.|| ||.    |.|  . |...| .|   .|  . 
lldlvrqvskaqqksgagpivvhCsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqtedqyefiydvllealasgdt

0042113 (Phosphotyrosine protein) phosphatases II 2-177 7.5e-39 129.0 In-house 60-241 (245) alignment
Range on Protein: 2-177
Range on HMM: 60-241/245.0
PLSQTVTDFLRLIYDYRISTIVMLNDLSKED--ASSIYWDEANPNIKQPFSMNVLDTVESEHWTERTLELK--HRKNTRIIQHFQFLSWKEVDSVDFYQT
||..|| ||.|......|.|||||...   .   .  || . ..     |....|..   ...| ||||..    . .| ..|...|.| . .  |  ..
PlpetvedfwrmlwelgittivmLteeeelgrvkcaqywplgesltygdftvtllseehlddytvrtlevtnlgddesrevihyhylpwpdhgvpdllel

LLDFMNNVTSQQG--GDSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNH
||||.. | ...   .. ||||||  ||||||.|... ..|.||| |  |.....|| ||    ...|... |. .|..| .
lldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleqlekelgvsleeavkelrsqRpgavqtpsqyrflyealle

subfamily_PTPRB_pd Subfamily PTPRB 2-184 3.9e-38 126.2 In-house 102-290 (293) alignment
Range on Protein: 2-184
Range on HMM: 102-290/293.0
PLSQTVTDFLRLIYDYRISTIVMLNDLSKEDA--SSIYWDEA-NPNIKQPFSMNVLDTVESEHWTERTLELKHRKNTRIIQHFQFLSWKEVDSVDFYQTL
|| .|| || |.... . |.|||| .|  .       || .  .| .    ..... . | |.|. |.|.....|..| .....|.|| . .  .  .||
PlpetvddfWrmvwekkssiivmltqlvekgkvkCeeYWPadeepvlyGdikvtlvaeeeledwvirelkiekekeerkvrqyhftsWpdhgvPektktl

LDFMNNVTSQQ---GGDSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMAMSQE
|||...| ...     ..|..|||  ||||||.|  ... |...| || ||.| || .||.. ....|. ..|   .. . .|.  ..|
ldfvrtvreaiektaskrPivvhCsaGvGRtGtfialdrllqaieeedyvdifgivaelReeRnllvqtekqYifihqcvldllrkkee

subfamily_Sponge-PTP11_pd Subfamily Sponge-PTP11 2-177 6.3e-38 125.3 In-house 99-281 (290) alignment
Range on Protein: 2-177
Range on HMM: 99-281/290.0
PLSQTVTDFLRLIYDYRISTIVMLNDLSKEDA--SSIYWDEANPNIKQPFSMNVLDTVESEHWTERTLELKHRKN---TRIIQHFQFLSWKEVDSVDFYQ
|.|.|. || .||.. ... |||| .  .|.      || ... .  ..||...|.  . .. .||.||.|....   .......|. .|.. ..|  .|
pvsntlvdFWkliwqekvtiivmltniieegkvkCqqYWpdsdtkaygefsikllneetlneyierklevknknsagakqsvtqyqitnwdstgkvtnpq

TLLDFMNNVTS--QQGGDSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNH
| |  .....    . |. ...||| ..|||..|||.... ... . |  .||||..| .|    ...|. . |.. ..|. .
tillvieemyktqrkrgntsivvHCSdtvgrsavfcaaattinkcktegvidvfqvlksqRiqkpgsvqtvqqyqgifqivlt

0045098 (Phosphotyrosine protein) phosphatases II 2-178 6.8e-37 122.8 In-house 72-271 (278) alignment
Range on Protein: 2-178
Range on HMM: 72-271/278.0
PLSQTVTDFLRLIYDYRISTIVMLNDLSKED--ASSIYWDEANPNIKQPFSMNVLDTVESEHWTERTLELKHR----KNT--RIIQHFQFLSWKEVDSVD
|| .|| ||.|......|..||||..|   .      || | .. .  .|. ..|.. . ...| |||.. .     ..   | ..|...|.| . .. .
Plpstvadfwrmlwelgitvivmltelvelgrekcaqywpeggsltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvps

FY--QTLLDFMNNVTSQQG--------------GDSPVLVHCLNGVGRTGVFCVVKMCLDQLevEDAVDVFQIVKALRHDNFQ-MIQSLEDYKLCYRILN
.   . .|.... . . .               .. ||||||  ||||||..... ..|..|  |. ||....|| ||    . ..|.|| |. .|. | 
lpilksflellefirealkllaslllsslllldsggpvlVHCsaGvgRtGtlvaaylmlell..eggvdlleavkelrsqRpglavqnleqyrflyefll

HL
.|
el

subfamily_Urchin-PTP-7_pd Subfamily Urchin-PTP-7 2-178 9.3e-37 121.6 In-house 100-278 (315) alignment
Range on Protein: 2-178
Range on HMM: 100-278/315.0
PLSQTVTDFLRLIYDYRISTIVMLNDLSKEDASS--IYWDEAnPNIKQPFSMNVLDTVESEHWTERTLELKHRKNTRIIQHFQFLSWKEVDSVDFYQTLL
|. ..| || ||.... |..||||..| ... .    || .    |  ....   .    ...| |||    ..| | .  ... || ...   .  .|.
pnvasvkdfwrlvfeedigkivmltnlvegekrkaekywpdk.kviyGkitvtrkseevnteytvrtlsvvfgdnirevvqlhytswpdmgvpkytiplm

DFMNNVTSQQG-GDSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHL
... .|   .    ....||| .|||||| |. ..  |||.|.|.|.||..... .|.   .|.|..| |.. | .|   
nlirtvkqhhtnsvgaivvhcsaGvGrtGtfitldavldqaeaenaidvynfitgvrqnrikmvqvaeqyqfiydallet

subfamily_Sponge-PTP5_pd Subfamily Sponge-PTP5 2-175 1.3e-36 120.9 In-house 83-262 (283) alignment
Range on Protein: 2-175
Range on HMM: 83-262/283.0
PLSQTVTDFLRLIYDYRISTIVMLNDLSK--EDASSIYWDEANPNIKQPFSMNVLDTVESEHWTERTLELKHR---KNTRIIQHFQFLSWKEVDSVDFYQ
|| .|| || ....| .|..||||  |    . . | || .       .| . . . . |. .. . | |..    |.| .. |.|.  | |..      
PldrtvvdfWkmvfdekitaivmltklqedlrikCsqyWPkrGsedyGeftvtlrkettsnsfiikelllrvnssakstlllahyqvidWleygeqaiin

TLLDFmNNVTSQQG--GDSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRIL
.|. | | | |.|    ..|..||| .|.|||.||. .   ....  |  ||||..|| .| .   ..|.|. ||| . . 
slvkf.nkvislqteskkgPivvhCstgiGrtavfiaasasvkdaltesvvdvfavvkimreqrmmavqtldqyklvhelv

subfamily_PTPRA_pd Subfamily PTPRA 2-178 3.1e-36 119.9 In-house 109-294 (330) alignment
Range on Protein: 2-178
Range on HMM: 109-294/330.0
PLSQTVTDFLRLIYDYRISTIVMLNDLS--KEDASSIYWDEANPNIKQPFSMNVLDTVESEHWTERTLELK------HRKNTRIIQHFQFLSWKEVDSVD
|...|| || |.|.... .||||| .|   ||.    || .          ..| |.......| | . ..      ..|..|... | | || .|    
PkeetvedfwrmiweqksativmltelkerkeekcaqywPdeGlvtyGnirvevedetvlvdytvrkflvqqlpdatrekksrlvrqfhftswPdvGvPf

FYQTLLDFMNNVTSQQG-GDSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHL
  . .|.....| ...    .|. |||  |||||| |.|..  |.... |  ||||..|| ||    ||.|..| |...|..| . 
epiGmlkllkkvkklnqqsagpivvhcsaGvGrtGtfivldavlervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvlley

subfamily_Ptp69D_pd Subfamily Ptp69D 2-182 3.6e-36 119.9 In-house 99-289 (307) alignment
Range on Protein: 2-182
Range on HMM: 99-289/307.0
PLSQTVTDFLRLIYDYRISTIVMLNDLSKEDA--SSIYWDEAnpNIKQPFSMNV--LDTVESEHWTERTLELKHRK-------NTRIIQHFQFLSWKEVD
|. .|. || |.| .  . .|||| .|.  .    . || .   ...|  ...|   .. . .....|.|.. . |       ..| .  .....||.. 
PveatigDfWRmiaeqevtlivmlsnlteknrkkcakYWpie..devqygdilvklvseekhsdyiiReldvskkkeesgevedsrkvvqyhytgWkDsk

SVDFYQTLLDFMNNV-TSQQGGDSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMAMS
  .  ..||.....|   ..   ||..||| .||||.|.|  ... |.||. || ||.|..|| ||..   ..|||| |. .|| |   . ..
vPevargllklieqvrelyklnrsPivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnllvqsleqYvflyralldyssyg

subfamily_Urchin-PTPRA_pd Subfamily Urchin-PTPRA 2-182 4.9e-36 119.6 In-house 112-296 (319) alignment
Range on Protein: 2-182
Range on HMM: 112-296/319.0
PLSQTVTDFLRLIYDYRISTIVMLNdlskEDASSIYWDEANPNIKQPFSMNVLDTVESEHWTERTLELKH---RKNTRIIQHFQFLSWKEVDSVDFYQTL
||  |. || |.|..|..||||.|     .|  | ||       .. | ..|    |.. .. | .|| .    |. | |. | || | .|   |.   |
PldntladfWrmiweyncstivllt....kdkcsqywplkivikeerfkvkvdsveetaeyvvrdielsedgkekdirkitqfhflGwpdvGvpdypsdl

LDFMNN---VTSQQGGDSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILN--HLMAMS
. ....   .||.. .  ...|||  |||||||. |... ||... |. |||...|. || .  ...|.| .||..|  |   ||.. |
mrlvkkvrhltskenhranivvhcsaGvGrtGvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleehlfghs

subfamily_Urchin-PTP-8_pd Subfamily Urchin-PTP-8 2-182 7.8e-36 119.0 In-house 76-260 (284) alignment
Range on Protein: 2-182
Range on HMM: 76-260/284.0
PLSQTVTDFLRLIYDYRISTIVMLNdlskEDASSIYWDEANPNIKQPFSMNVLDTVESEHWTERTLELKH---RKNTRIIQHFQFLSWKEVDSVDFYQTL
||  |. || |.|..|..||||.|     .|  | ||       .. | ..|    ||| .. | .|| .    |. | |. | || | .|   |.   |
PldntladfWrmiweyncstivllt....kdkcsqywplkivikeerfkvkvdsveeseeyvvrdielsedgkekdirkirqfhflgwpdvgvpdypsdl

LDFMNN---VTSQQGGDSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILN--HLMAMS
. ....   .||.. . ....|||  |||||||. |... ||... |. |||...|. || .  ...|.| .||..|  |   ||.. |
mrlvkkvrhltskenhranivvhcsagvgrtgvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleehlfghs

subfamily_Sponge-PTP10_pd Subfamily Sponge-PTP10 2-179 6.6e-35 115.5 In-house 94-278 (287) alignment
Range on Protein: 2-179
Range on HMM: 94-278/287.0
PLSQTVTDFLRLIYDYRISTIVMLNDLSKEDAS--SIYWDEANPNIKQPFSMNVLDTVESEHWTERTLELKHRK---NTRIIQHFQFLSWKEVDSVDFYQ
|...|. .| .|| | ....|||| ..  .| .    || | .  .  ......|.   .....||.||.|...   ... .. .|. .|..   |  .|
PmfntarnfWkliddrnvtaivmlcqekendeevcyqyWpeeksvvlGeyniellneevnagyierklevknknkagdkqqvkqyqitnWdstgkvtepq

TLLDFMNNV--TSQQGGDSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLM
| |  ...   | .. |.....||| ..|||...|| . . ... . | ..||||..|  |    ...|  | ||  . |. . .
tillvieemyktqrkrgntsivvhCsdtvGrsamfcaaattinkckteGviDvfqvlksqriqkpgsvqtveqykfindivleyl

subfamily_PTPN5_RR_pd Subfamily PTPN5_RR 2-178 9.2e-35 115.0 In-house 81-267 (274) alignment
Range on Protein: 2-178
Range on HMM: 81-267/274.0
PLSQTVTDFLRLIYDYRISTIVMLNDLSKEDA--SSIYWDEANPN-I---KQPFSMNVLDTVESEHWTERTLELKHRKNTRIIQHFQFLSWKEVDSVDFY
||..||.|| |.||  ... |||| .|. ..    . |. .|.   |    . ....| ..|| .... |.| ||. ...| ..|. . .| . .| |  
PlpntvadfWrmiyqeevqvivmltklkeaneqkCavyfPdaedyeiserygdveikvekiverndysvrklvlkylerersvkhywytdWPdhksPdda

QTLLDFMNNVTSQQ---GGD-SPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHL
.||||....| ...       .||.|||  |.||||.|  ..... ||. |  |||..||  || |   |.|. | |.| .|.| . 
ntlldlvleveesreeenaklapvvvhCsaGiGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralcly

subfamily_CG7180_pd Subfamily CG7180 2-180 7.7e-34 111.7 In-house 93-291 (296) alignment
Range on Protein: 2-180
Range on HMM: 93-291/296.0
PLSQTVTDFLRLIYDYRISTIVMLNDLSKEDA-SSIYWDEANPNIKQPFSMNVLDTVESEHWTERTLELKHR------------KNTRIIQHFQFLSWKE
|  .|| .| ||.||  ||..|.| .          || .   .  ... .... . .  . . ||. |...             .|||...||.  |. 
pkketvdefWrlvydeeisavvvLtktfdfakmypsywpnkskeqygeifveiveekqyanlkirtfkltkkivalteqekqvkaetRivklfqlteWel

VDSVDFY-QTLLDFMNNVTSQQGGD------SPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMA
 |.| .  ..|..... | . ..        .||.|.. .|..|.||.. . ..|...| |. ||||. || ||..  |.... |.|| .| .|.. . 
edkvPlstnalielrrrvrlwrekvdedpeegPvvvvssdGasRsGvylaidanlelvekeeevdvFeavktlrrsRpqLvenveeYkyiYdvlleavl

subfamily_Sponge-PTP9_pd Subfamily Sponge-PTP9 2-183 3.2e-32 106.4 In-house 93-297 (301) alignment
Range on Protein: 2-183
Range on HMM: 93-297/301.0
PLSQTVTDFLRLIYDYRISTIVMLNDLSKE--DASSIYWDEANPNIK--QPFSMNVLDTV-----------------ESEHWTERTLELKHRKNTRIIQH
|. .|..|| |||.... ..|||. .| ..  . .  || ... . .   ||.. . ..                   ..  .||... |..|... .  
pmkktlvdfWrliwqekpvsivmvtnlkegtkskceqywpnseaeseefgpftvtlvneqvyPdfvirqlnvkiqdgsnngyierkfkvksdksswdvlq

FQFLSWKEVDSVDFYQTLLDFMNNVT--SQQGGDSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHL
.|  .| .   |  ..| |  ...|    |. | .||.||| ..|.|.||.| | . |.|   |  |||||..||.|.    ... || |   | ...  
lqvtdWpqdGvvreprtvLqviddvihrqqkigggpvvVHCSdtVsrsGvYcsvsiglEQckaegVVdvfqvtkavrrskpgaVtTLeqytsiydvidmy

MAMSQ
... .
lqlns

subfamily_PTPN12_pd Subfamily PTPN12 2-182 1e-31 104.9 In-house 91-280 (290) alignment
Range on Protein: 2-182
Range on HMM: 91-280/290.0
PLSQTVTDFLRLIYDYRISTIVMLNDLSKED--ASSIYWDEANPNI--KQPFSMNVLDT-VESEHWTERTLELKHRKNTRIIQHFQFLSWKEVDSVDFYQ
||..|..|| |.|...... .||.  .   .      || | . .    ..|.... .    .. .. |||.....|..|... |.. .| . .     .
PLpktlddfWrmiweknveivvmaCrevelgkkkCerYWpeegeeelefgefevtleeekavdddflirtLkveaqkesrkvyqfhYtaWPDhgvPssak

TLLDFMNNVTSQQ-GGDSPVLVHCLNGVGRTGVFCVVKMCLDQLEV---EDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMAMS
.||.....| . |   |.|..|||  ||||||. ... .  ..|.    .. .|||..|  ||..   ..|. | |.| |. . .|.  .
sllelielvrelqesedaPlvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelvqke

subfamily_PTPRG_pd Subfamily PTPRG 2-189 1e-31 104.8 In-house 99-296 (563) alignment
Range on Protein: 2-189
Range on HMM: 99-296/563.0
PLSQTVTDFLRLIYDYRISTIVMLNDLSKED--ASSIYWDEANPNIKQPFSMNVLDTVESEHWTERTLELKH--------RKNTRIIQHFQFLSWKEVDS
|| .|. || |.|.. . ..|||. .| ..      .|| . ..   . ....  ..      |.||| .|.        ... . ...... .| ....
plkdtfddFWrmiWeqnvaiivmitnlvergrrkcdvYWPkdesetygalqvtlieeevlalytvrtlviknlklkkkkqcdteklvrqyhytkWPdhgv

VDFYQTLLDFMNNVTS-QQGGDSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMAMSQENtLQS
 ..    | |..     ..    |..||| .||||||...|..  | |.. |.||.||...| .|     ..|. |.|   . .|  ..|  ... |..
PehslpvLifvkkssaankaeaGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvqteEqYiflhdalleaiaskete.lla

subfamily_PTPN23_pd Subfamily PTPN23 2-175 8.3e-31 101.9 In-house 91-276 (288) alignment
Range on Protein: 2-175
Range on HMM: 91-276/288.0
PLSQTVTDFLRLIYDYRISTIVMLNDLSKEDAS--SIYWDE--ANPNIKQPFSMNVLDTVESEHWTERTLELKHRK--NTRIIQHFQFLSWKEVDSVDFY
|| .|. || ...|. . |.|||| . .. .    . || |   ...  ...|. . .. |.|.. ||.|.|....  ... ..| |. || |.   .  
PlqstlnDFWlmvyeqkssviVmllskeelgkpkvdrYwPedkgetvkfgdlsvtlksvretethvervlkletldadavksvshlqltsWpelGvPasP

QTLLDFMNNVTS-----QQGGDSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDA-VDVFQIVKALRHDNFQMIQSLEDYKLCYRIL
.|||.|...| |     |.  . |..|||. ||||||||..|   . .||...  .|. |.|. ||..   |.|  | .| .| . 
etllqfldevesayeavqrksktPlvvhCsaGvgRtgvfalvyaavrelekgnglldiiqvvsrlreqRrfmvqekeqlkfsyeav

subfamily_PTPN3_pd Subfamily PTPN3 2-176 4.2e-30 99.6 In-house 92-273 (280) alignment
Range on Protein: 2-176
Range on HMM: 92-273/280.0
PLSQTVTDFLRLIYDYRISTIVMLNDLSKEDA--SSIYWDEANPNIK-QPFSMNVLDTVESEHWTERTLELKHRK--NTRIIQHFQFLSWKEVDSVDFYQ
||..|.||| ..... ..|.|||| .|  .       || | . ...   ||...  . |.. .  | | ||...  . | | ..|.|.| . .  |  .
PlaktatdfWqmvweqksslivmlttlverGrvkChqyWPetedeleygefsvkcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsa

TLLDFMNNVTSQQ-GGDSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKL-CYRILN
 .|.|...| ... | ..||.|||  |.|||||. .....|  .| ...| . .||. .|     ..|. . ||. |  ||.
dflefvervrklrsgkeePvvvhCsaGigrtGvlilletalalieaaepvypldivrtmrdqramlvqtasqykfvCeailk

subfamily_Choan-PTP-2_pd Subfamily Choan-PTP-2 2-179 1.4e-29 98.0 In-house 72-264 (270) alignment
Range on Protein: 2-179
Range on HMM: 72-264/270.0
PLSQTVTDFLRLIYDYRISTIVMLNDLSKE--DASSIYWDEANPN-IKQPF-SMNVLDTV--ESEHWTERTLELKHRKNTRIIQHFQFLSWKE------V
||  |...|.|.|.. . ..|||. .|  .  .  . || . . . .|  .  ..|| .    .| .  . |.|... ..| . ||.. .| .       
PlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkekvkledgkikvlalseekeegyiltrlrleekgeerrlvHfwyntWpdhgvpree

DSVDFYQTLLDFMNNV--TSQQG-GDSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLM
||.   . ||  ...|  ....    .|.|||| .||||||.. .. ...  || .  ||| .|...||.|  ...|  | |.. |. . . .
dsslstdqllkmlravrrsekeldkaePllvHcsaGvgRtGtlialDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyeflykavveya

subfamily_PTPN9_pd Subfamily PTPN9 2-175 2.8e-29 97.1 In-house 93-286 (297) alignment
Range on Protein: 2-175
Range on HMM: 93-286/297.0
PLSQTVTDFLRLIYDYRISTIVMLNDLSKED--ASSIYWDEANPNIKQ--PFSMNVLDTVESEHWTERTLELKH--RKNTRIIQHFQFLSWKEVDSVDFY
|| .||.|| |.... .. .|||   .  .     . ||.. . . ..   .|.......|.|....|.||.|.   ...| . ||||||| .    .  
plkktvsdfWrmvWeqevlvivmttrvvergrlkcgqyWpleeessaefgdlsvsnveveeeedykvrvleiknvkteesrkvthfqflsWPdyGvPssa

QTLLDFMNNVTSQQG--------------GDSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRIL
..|||....| ..|.               . |..|||  |.|||| |. . .||..|| .. |||.. || ||     .||  | |..||  .
aslldvlekvrekqalavkelgdewkghpsgPPivvhcsaGiGrtGtfitldiclsrleevgtvdvvetvkllrtqrafsiqtpeqyefcylav

subfamily_Choan-PTP-1_pd Subfamily Choan-PTP-1 2-180 4.9e-28 93.0 In-house 92-277 (281) alignment
Range on Protein: 2-180
Range on HMM: 92-277/281.0
PLSQTVTDFLRLIYDYRISTIVMLNDLSKEDA--SSIYWDEANPNIK-QPFSMNVLDTVESEHWTERTLEL-KHRKNTRIIQHFQFLSWKEVDSVDFYQT
|. .....| ........|.|||.    ...      || . | ..|   . .. . . |.... ||...| ..  .|| ........| .    .  . 
PvPaslvafWqmvweqkvsaivmvtreieagklkChrYWPddnselkygdvtvkstaeeekatyierkfkleresgetreveqlaytaWPdhGvPattke

LLDFMNNVTSQQG--GDSPVLVHCLNGVGRTGVFCVVKMCLDQLEVE-DAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMA
||.| ..|.. .    . |...||  ||||||..  .   ....| |   .|| ..|. ||..   |.|..  |.  |... . . 
llefrkevlkltekktkaplvihCsaGvGrtGtyialDrlvkaveaeleeldvkavvaelrkernlmvqtvvqyefvykavldald

subfamily_PTPN13_pd Subfamily PTPN13 2-180 3.7e-27 90.3 In-house 85-270 (273) alignment
Range on Protein: 2-180
Range on HMM: 85-270/273.0
PLSQTVTDFLRLIYDYRISTIVMLN-DLSKED-ASSIYWDEANP---NIKQPFSMNVLDTVESEHWTERTLELKHRK--NTRIIQHFQFLSWKEVDSVDF
|| .||.|| ..... . . |.|.  .  |.      || | .     ... . ...|.... . .. |.|..|. .  ..| ..|..| .| . .    
PlPetvkdfwqmvweqkaeviamvtlekekgkvkchrywPesknkklkvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPss

YQTLLDFMNNVTSQQGGDSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMA
 . || |. .| . |   .|..|||  |.||.|.. .... |. .| .  .|| .||. ||.    ..|. . | ..|... ... 
aaellqfvaevrrlqtdagPivvhcsaGiGrsGtlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykailevlk

0051429 (Phosphotyrosine protein) phosphatases II 2-179 5.6e-27 90.5 In-house 30-225 (272) alignment
Range on Protein: 2-179
Range on HMM: 30-225/272.0
PLSQTVTDFLRLiYDYRISTIVMLNDLS--KEDASSIYWD------------EANPNIKQPFSMNVLDTVESEHWTERTLELK---HRKNTRIIQHFQFL
||  |. || || ....|.|||.| ...  . .  . ||             .| .     ... .| ..  .... |.|.|.   . ...| . |....
plpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseellldyilrellltlllsagearevmhlhyt

SWKEVDSV-DFYQTLLDFMNNvtsqqggDSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVD--------VFQIVKALRHDNFQMIQSLEDYKLCYRIL
.|       . . .||.....       . ||||||  |..|||..... ..| ... |. ||        ....|. ||    ...|. | |. .|..|
dwpdhgvpqeallellellld.......ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlyleeaveelraqrpgavqteeqylflyeal

NHLM
 .|.
lell

0041856 (Phosphotyrosine protein) phosphatases II 2-179 1.5e-26 88.5 In-house 42-171 (182) alignment
Range on Protein: 2-179
Range on HMM: 42-171/182.0
PLSQTVTDFLRLIYDYRISTIVMLNdlskedaSSIYWDEANpnikqpfsmnvldtvesehwtertlelkhrknTRIIQHFQFLSWKEVDSVDfYQTLLDF
|| .|| ||||......|.|||.|.       .  || |                                  .| . ....|.|   .  |  ..||||
pllstvadflrmlkelgittivnlt.......eelywpell................................erlgiqylylpwpDhgvpd.ldelldf

MNNVTSqqgGDSPVLVHCLNGVGRTGVFCVVKMCLDQlevedAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLM
.. | .    . ||||||  ||||||....  ... .      |.....|| .|   ..|..... | .....| .|.
ieevle...eggpvlVHCsaGvgRtgtlvaaylmkkl.....gvsleeavklvrsrRpgmvitpnqyfflqlallell

subfamily_PTPRN_pd Subfamily PTPRN 2-174 1.9e-26 87.4 In-house 108-287 (297) alignment
Range on Protein: 2-174
Range on HMM: 108-287/297.0
PLSQTVTDFLRLIYDYRISTIVMLNDLSKEDASSI--YWDEANPNIKQPFSMNVL-DTVESEHWTERTLELKH--RKNTRIIQHFQFLSWKEVDSVDFYQ
||..||.|| .....  .  ||.|  |..|. .    || .   .. . . .... . . .. .  |.. ||    ..|| .  | ||||.| .     .
plastvadfwqmvweqGvvvivnltrleeegvkqckrywpdeGsevyhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasak

TLLDFMNNVT-SQQGGDSPVLVHCLNGVGRTGVFCVVKMCLDQLEV-EDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRI
.||.|   |  | .|  .|..||| .|.|||||.... . |..|      .|.   .. || .  ..... .......  
sllefrrkvnksyrGrscpivvhcsdGaGrtGvyilidlvlnrllkGvkeidiaatlehlrdqrpglvktkdqfefalta

subfamily_PTPN14_pd Subfamily PTPN14 2-179 1.6e-24 81.4 In-house 101-296 (300) alignment
Range on Protein: 2-179
Range on HMM: 101-296/300.0
PLSQTVTDFLRLIYDYRISTIVMLNDLS--KEDASSIYWDEANPNIK----QPFSMNVLDTVESEHWTERTLELKHR--KNTRIIQHFQFLSWKEVDSVD
|| .||.|| .....  .. |||| .      . |  |. . . . |    . | .    . .|.  . ..|.|||   |. | . |.|.  | . .  .
PleltvqdfWqmvWeqgvqlivmlteeeedgkeksfkyfPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPe

FYQTLLDFMNNVTSQ----------QGGDSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLM
  .. |.....| |           .  . ||||||..|||||||  .. . .  || .. .|. .... ||.    ..|.|  ||  |..| . .
DvkgflsyLeevqsvrrktnseveskeskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLreqrmllvqtlaqYkfvYkvlikyl

subfamily_Sponge-PTP6_pd Subfamily Sponge-PTP6 2-203 1.7e-24 81.1 In-house 99-301 (439) alignment
Range on Protein: 2-203
Range on HMM: 99-301/439.0
PLSQTVTDFLRLIYDYRISTIVMLNDLSKEDAssiYWDEANPNIKQPFSMNVLDTVESEHWTERTLELKHR----KNTRIIQHFQFLSWKEVDSVDFYQT
|  .|. || ||... . .||||| .| .      ||   .  .    .. |   .|  ... | . .  .    .. | . .|....| . .       
pkkettddfwrlviekktvtivmltnlvesyk...ywpsdaevcygdiavrvdrnielpnyvirgfkvfnerdttekertvlqfhyiawpdknvpaqash

LLDFMNNVTSQQG--GDSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMAMSqeNTLQSGQEFDM
.|||.  . | .      ||.|||  ||||||    . ..|.|| .|. ||.  ||| ||..  ||.|.| .| . |  .   .     ..  . .||  
vldflrainsandkeeygpvvvhcsagvGrtGtiialdialeqlklenkvdikgivkvlrkqrkqmvqalcqyvfiynavledivyG..diavtidefkk

EKDDGLSE
| . |.| 
efnagfst

0043147 (Phosphotyrosine protein) phosphatases II 2-172 6.3e-24 80.0 In-house 28-154 (172) alignment
Range on Protein: 2-172
Range on HMM: 28-154/172.0
PLSQTVTDFLRLIYDYRISTIVMLNDLskedassiywdeanpnikqpfsmnvldtvesehwtertlELKHRKNTRIIQHFQFLSWKEVDSVdFYQTLLDF
||. |. ||.|..... |..||.|..|                                       ..   . .| . ....|.|   .     . ||.|
plrntladfwrmlkelgithivnltel.......................................lydpellerlgiqylylpwpDhgvp.llelllef

MNNVTS--QQGGDSPVLVHCLNGVGRTGVFCVVKMCLdqleveDAVDVFQIVKALRHDNFQMIQSLEDYKLCY
.. . .  ..  . ||||||  ||||||....  ..|        ......|. .|.  ....|. . |...|
lefidellalspggpvlVHCsaGvgRtgtlvaaylml......lglsleeavalvrekRpgavqnpsqyrfly

0049772 (Phosphotyrosine protein) phosphatases II 2-180 1.2e-23 79.8 In-house 92-281 (314) alignment
Range on Protein: 2-180
Range on HMM: 92-281/314.0
PLSQTVTDF----------LRLI--YDYRISTIVM---------------------LNDLSKEDassiywdeanpnikqpfsmN------VLDTVesehw
||. || ||          .|..  .|... .|||                     |..|.                      |      . .       
pleitvvdfreepvlyyngwrmvlrgdlnvrdivmsrdevladelsrLdaAlgKtpllildgng...................neptaadlellk.....

tERTLELKHRKNT-RIIQHFQFLSwKEVDSVDFYQTLLDFMNNVtsqqGGDSPVLVHCLNGVGRTGVFCVVKMCLDQLEVeDAVDVFQIVKALRH--DNF
 |.. . .. ...     .. .    .... .... .|.|....      ..||||||  |.||||.|.|. ... .| | .. .... |.. |.   |.
.eelydpelferlgikylripvpD.gsaplledfdeflefieea....dkggpvlvHCkaGkgRtgtfvvaaylmkllgv.sleealedvrlkRpinpnp

QMIQSLEDYKLCYRILNHLMA
 .|..||.|  ....|.... 
gfieqleqyefilealleylk

0049260 (Phosphotyrosine protein) phosphatases II 2-173 8.1e-23 76.2 In-house 17-144 (152) alignment
Range on Protein: 2-173
Range on HMM: 17-144/152.0
PLSQTVTDFLRLIYDYRISTIVMLNDLSKED--ASSIYWdeanpnikqpfsmnvldtvesehwtertlelkhrkntriiqHFQFLSWKEVDSVDFYQTLL
|...|. ||.|..... |.|||||..|.  .      |.                                         ....| |      |. | ||
pgpntladfwrmlkelgittivmltellelgklkceqyi.........................................qylhlpwpDhgvpdlsqlll

DFMNNVTS-QQGGDSPVLVHCLNGVGRTGVFCVVKMCLdqleveDAVDVFQIVKALRHDNFQMIQSLEDYKLCYR
...  .   ..  . ||||||  ||||||....  ..|        |.....|. .|  . ..... . ....| 
flllfieklaldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpgqlrflye

0046846 (Phosphotyrosine protein) phosphatases II 2-177 1e-22 76.2 In-house 31-171 (176) alignment
Range on Protein: 2-177
Range on HMM: 31-171/176.0
PLSQTVTDFLRLIYDYRISTIVMLNDLSKEDAS--SIYWDE-ANPNIkqpfsmnvldtvesehwtertlelkhrkntriiqHFQFLSWKEVDSVDFyQTL
|| .|. |||.......|...|.|...   .      ||.|  ...|                                  ....| | . .  |. . |
plprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgi..................................qylhlpwpDhgvpdl.ell

LDFMNNVTSQQGGDSPVLVHCLNGVGRTGVFCVvkmcLDQLEVEDAVDVFQIVKALRHDNF-QMIQSLEDYKLCYRILNH
|.... . ...  . ||||||  |.||||....    .. || |  ..|..... .|   . ...|. | |. .|. . .
lellefirealkeggpvlVHCsaGigRtgtlva....ayllelekglsveealalvreqRplgavqtpeQyrflyefell

subfamily_Sponge-PTP1_pd Subfamily Sponge-PTP1 2-177 1.3e-22 75.1 In-house 80-257 (267) alignment
Range on Protein: 2-177
Range on HMM: 80-257/267.0
PLSQTVTDFLRLIYDYRISTIVMLNDLSKEDaSSIYWDEANPNIKQPFSMNVLDTVESE--HWTERTLELKHRKNT-RIIQHFQFLSWKEV-DSVDFYQT
||..|.|||| .| |.....||.|    ...    .|     . |.   . |  ..| |   .   ||||| .... . .  . .  |.   .   . . 
plkntitdfltvihdqkvpvivlltkvftdn.irlfwPPkmgqakkyqdltvehslekeendyqiitlelkfknesahnvtlyyykkwnintnnkpylkp

LLDFMNNVtSQQGGDSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNH
|.  . .    . |. |..|.| .||||.| | |..  |...  |. .|.|. .. .|.    .....| |  ....| .
lfgilakn.qlengnrPlvvacsdGvGrsGtflvidsqleraktegvsdifdflrkirsqriglvdtkeryiyihellae

subfamily_PTPN1_pd Subfamily PTPN1 2-185 2.5e-22 73.9 In-house 79-278 (290) alignment
Range on Protein: 2-185
Range on HMM: 79-278/290.0
PLSQTVTDFLRLIYDYRISTIVMLNDLSKEDA--SSIYWDEANP--NIKQP---FSMNVLDTVESEHWTERTLELKH--RKNTRIIQHFQFLSWKEVDSV
||..||. | ..... .  ..|||| .  ..      || . .   ...     ...... . .....| |.|||.    ..|| | || ...| .    
PlpntvdhfWqmvWeqkskavvmlnkvvekeqikcaqywPqgeeekellledtklkvkliseerksyytvrllelenlktqetreilhfhyttwpdfgvp

DFYQTLLDFMNNVT---SQQGGDSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDA---VDVFQIVKALRHDNFQMIQSLEDYKLCYR-ILNHLMAMSQEN
.  ...|.|. .|    | .    |...||  |.||.| ||.|  || ..| .|    ||. . . .||.  . .||  .  .. |  ||.    . ...
espaaflkflfkvresGslssdvGpavihcsaGiGrsGtfclvdtclvliekkddlssvdikkvllelrkyrlGliqtadqlrfsylaileGakvikgds





subfamily_Choan-PTP-3_pd Subfamily Choan-PTP-3 2-176 6.1e-22 72.7 In-house 88-274 (287) alignment
Range on Protein: 2-176
Range on HMM: 88-274/287.0
PLSQTVTDFLRLIYDYRISTIVMLNDLSkEDASS---IYWDEAN-PNIKQPFSMNVLD-TVESEHWTERTLELKHR--KNTRIIQHFQFLSWKEVD----
|.. || || |.... | ......     |.|      || | . |     .|. .|| .. . ... |.| | .   ...|... ...||| .      
Piaatvrdfwravletrsasvitmtrev.eearlkcykywPerevPmrvGGysvvlldydikePeygvralrlidletrearvvkqldllswPdkvlaPt

SVDFYQTLLDFMNNVTSQQGG--DSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILN
.| . .  ||  ...  .. .    |..||.  |.||.|..  . .....||    ||| ..|  ||     ..|.   ..| |  | 
avglirfvldvkqhielardasevGPlvvhddvGiGrsGillatlvlvsrledlGrvdvaavvirlreyraalvqavvqlrllyealv

subfamily_Anemone-PTP-4_pd Subfamily Anemone-PTP-4 2-172 9e-21 69.2 In-house 53-232 (237) alignment
Range on Protein: 2-172
Range on HMM: 53-232/237.0
PLSQTVTDFLRLIYDYRISTIVMLNDLSKE--DASSIYWDEAN-PNIKQPFSMNVLDTVESEHWTERTLELKHR---KNTRIIQHFQFLSWKEVDSVDFY
||  .  || ..... . | ||||  | .        || ... |.    ... .    |   .| |.| | .|   |. |.|. .|| || .    .  
plesscddfwqmvwqekcsvivmltgliegnelkchkywpstdqpaaygvltvslkkkeefsdytvrslllskrltlkevrlihqyqftswpdrgvpqqt

QTLLDFMNNVTSQQGG---DSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCY
 .|| |  |.  .       .| ..||  ||||||.| |.   | | . .  ||... |...  |   .||. ..| . .
aallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlrqakekkvvdiynyvysieedrpyiiqtkdqyvfih

subfamily_Nvec-PTP-3_pd Subfamily Nvec-PTP-3 2-173 7.6e-20 65.9 In-house 12-197 (198) alignment
Range on Protein: 2-173
Range on HMM: 12-197/198.0
PLSQTVTDFLRLIYDYRISTIVMLNDLSKED--ASSIYWDEANPNIKQPFSMNVLDT-VE-SEHWTERTLELK----HRKNTRIIQHFQFLSWKEVD--S
|| .|..|| .....     |||.||  |.     ..||  ..    .  |..|    .     .|  .| |         || | |.|| ||||     
plretladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqftswkekttpn

VDFYQTLLDFMNNVTS--QQGGDSPVLVHCLNGVGRTGVFCVVKMCLDQLEVE--DAVDVFQIVKALRHDNFQMIQSLEDYKLCYR
| ..  ..    .|.   .|  |.||.||| .| | ||||  . . .   |      ||.|.. | ||     .| ||. |.. |.
valfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiyq

subfamily_Anemone-PTP-3_pd Subfamily Anemone-PTP-3 2-173 8.3e-20 65.8 In-house 13-198 (199) alignment
Range on Protein: 2-173
Range on HMM: 13-198/199.0
PLSQTVTDFLRLIYDYRISTIVMLNDLSKED--ASSIYWDEANPNIKQPFSMNVLDT-VE-SEHWTERTLELK----HRKNTRIIQHFQFLSWKEVD--S
|| .|..|| .....     |||.||  |.     ..||  ..    .  |..|    .     .|  .| |         || | |.|| ||||     
plretmadfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqftswkekttpn

VDFYQTLLDFMNNVTS--QQGGDSPVLVHCLNGVGRTGVFCVVKMCLDQLEVE--DAVDVFQIVKALRHDNFQMIQSLEDYKLCYR
| ..  ..    .|.   .|  |.||.||| .| | ||||  . . .   |      ||.|.. | ||     .| ||. |.. |.
valfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiyq

subfamily_Cele-PTP-8_pd Subfamily Cele-PTP-8 2-181 7.2e-18 59.6 In-house 90-273 (288) alignment
Range on Protein: 2-181
Range on HMM: 90-273/288.0
PLSQTVTDFLRLIYDYRISTIVMLNDLS-KEDASSIYWDEANPNIKQPFSMNVLDTVESEHWTERTLELKHRKNTRIIQHFQ------FLSWKEVDSVDF
||  |.  . ... .  .  ||||..|  |    |  .   .   |  .  .  .. ..    ......   .... ... .      .| |..    . 
PlngtieelWkmllesdveyivmlcellekGkeksaeyfPsklGekarigrlctvvkkkradidklvkvsllriskegeekvivkilhlleWdddgvPen

YQTLLDFMNNVtsqQGGDSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMAM
|.. | ... .   .  . |..||. .|||||| . .. . |..| ..| . . .... || . |. ||.   |   .|.. . ...
ylsplrllevl...kslqkPivvhssaGvGrtgtlililialeslrlddflgirsllaklreerfkaiqtemqylyvhrcvleelll

subfamily_Cele-PTP-20_pd Subfamily Cele-PTP-20 2-172 1.1e-16 55.3 In-house 102-276 (290) alignment
Range on Protein: 2-172
Range on HMM: 102-276/290.0
PLSQTVTDFLRLIYDYRISTIVMLNDLSKEDA--SSIYWDEANPNIKQPFSMNVLDTVE---SEHWTERTLELKHRKNT--RIIQHFQFLSWKEVDSVDF
.| .|| |. |.. . ....|||| .| ..     . |. | . ..    .. || . |    ..   .|| ......    ...|..  || .      
alkdtvidiwrmvlqekvaaivmlceliedGkakceqyypekeGevltfGeitvlcseeddkdaniikktlsvrdkdsGkehklkhlkikswpdksvals

YQTLLDFMNNVTSQQGgdsPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCY
  .||  .  .    |   || |||  |.|||| |  ....|. |    ..|. ..|.|||.   . .|   .| .  
tlallrtlrilrkasG...pvvvhcsaGiGrtGtfvaievglqilldGkeldlldlvralrnsrlnsvqvdiqylalv

subfamily_Cele-PTP-19_pd Subfamily Cele-PTP-19 2-167 1.5e-16 55.0 In-house 98-269 (301) alignment
Range on Protein: 2-167
Range on HMM: 98-269/301.0
PLSQTVTDFLRLIYDYRISTIVMLNDLS--KEDASSIYWDEANPNIKQ--PFSMNV--LDTVESEHWTERTLELKH---RKNTRIIQHFQFLSWKEVDSV
||..|  ||  ..  | . .||||      .|.  . |     ..  .   |....   ... ... ..||||..    . .|| . |.|. .| . .  
PlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkisekldigrfkikiknkelilnkkiskrtlevedstgkfatrtvthyqysewtdrgvP

DFYQTLLDFMNNVTSqqgGDSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLED
  .  | |.|. |      . |..||| .|.||.  |   ..   ..| .  ... . .| ||.. .. .|  . 
kshaelfdlmelvkk...sekPivvhcsaGiGrsvafigteylareveadptieltealkhlrehrwngvqtnsq

subfamily_Cele-PTP-10_pd Subfamily Cele-PTP-10 2-177 1.4e-12 41.9 In-house 104-288 (305) alignment
Range on Protein: 2-177
Range on HMM: 104-288/305.0
PLSQTVTDFLRLIYDYRISTIVMLNDLSKE--DASSIYWDEANPNIKQPFSMNVLDTVESEHWTERTLELK-------H-RKNTRIIQHFQFLSWKEVDS
|| ||. .|  .. . ..  ||||    .      . ||  |. . ..  |  |.. |   .  ||  |..       .  ...  ..|.|.  | .   
pldqtidefwwmviqnkveqivmlcktvelgklkcaqywpaaqgeklelksgivvenvsgskpmerdaeiqitllnltysgdqkmsvrhlqwtewpdrgv

VDFYQTLLDFMNNVtsqQGGDSPVLVHCLNGVGRTGVFCVVKMCLDQL-EVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRIL-NH
     | |...  .   .|   |..|||  |.||||    ..  |... |  ..  . ..||||| .    ||.  .|   .|.. |.
ppckltslellsai...rgskvpivvhcsagigrtgtivaieyilekiaenkpcppmpelvkalrdqrafsiqndvqylfihrvmlny

subfamily_ptpA1_pd Subfamily ptpA1 2-139 7.9e-11 36.3 In-house 97-256 (418) alignment
Range on Protein: 2-139
Range on HMM: 97-256/418.0
PLSQTVTDFLRLIYDYRISTIVMLNDLSKED--ASSIYWDEAN--------PNIK---QPFSMNVLDTVESE--HWTERTLELKHRKNTRIIQHFQFLSW
|| .|..|| |.... |   ||||.  |..       || |           | .     .|..... ..        | . |    .|| | ..|.  |
plpntiadfwrmvwenrcriivmlsresencrikcdrywpeqiggeqfsiygngnevfgtysvelveviqdpereiitrnirltfegetrditqyqyegw

KEVDSVDFYQTLLDFMNNVTSQQG-------GDSPVLVHCLNGVGRTGVFCVVKMCLDQL
 . .  |. | . ... ..| .|         . |..|||  |||||| ||   . . .|
pdhnipdhtqpfrqllhsitnrqnqiipssdrnvpiivhcsagvgrtgtfctavimmkkl

subfamily_Cele-PTP-15_pd Subfamily Cele-PTP-15 2-176 1.6e-10 35.4 In-house 83-267 (285) alignment
Range on Protein: 2-176
Range on HMM: 83-267/285.0
PLSQTVTDFLRLIYDYRISTIVMLNDLSKE--DASSIYWDEANPNIKQPFSMNV-LDTVESEH-----WTERTLELKH--RKNTRIIQHFQFLSWKEVDS
|| .|..|| ..||. .|. ..||  | .   .  ..|. |   .. .    .. |  .. |      .   |.        .   ..| |   | .  .
plpetlsdfwhmiyqekiayvlmlctlfeggvekcalyypeklgevvkfgkyeitlteckeeaiagtilnaltvintedasseplymnhvqvpwwpdqla

VDFYQTLLDFMNNVTSQQGGDSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILN
 .  . .... . |   .  . |. |||  |||||  |  .  .  ..  .  .....||. .|   || .||  .. . | .| 
pedarpmielykwvkkvnpkekpicvhcsagvgrtatfvgidyatirimenpniemldivremramrfqavqshmqflflyvvlm

subfamily_egg_pd Subfamily egg 2-205 7e-10 33.1 In-house 91-292 (307) alignment
Range on Protein: 2-205
Range on HMM: 91-292/307.0
PLSQTVTDFLRLIYDYRISTIVMLNDLSKEDASSIYWDEANPN--IKQP--FSMNVLDTVESEHWTERTLELKHR---KNTRIIQHFQflsWKEVDSVDF
||  || || |...  ..  ||||.   . .    ||  |. .  .  |  . .. |.  .      |  .||     .. | ..|.|   .    | | 
plkntvddfwrmvfqeevqyivmltsrkeserceyywpkaesdslvtvpGslrienlkvdskadplfrvtklklvGgddeerflehwq...gdvnnssdv

YQTLldfmNNVTSQQGGDSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEdAVDV---FQIVKALRHDNFQMIQSLEDYKLCYRilnhLMAMSQENTLQSGQ
|  |    . .   .    ||.|.. .|| .....  ... | .|     .      . |. ||      ..|   | . ||    |...   . . | .
yspl....rvlrklrnlskpvvvqdilGvskaatlvaieiallsllrG.pitkslvlravvflrlrrrlsvesvllylfvyr....lvlfffrdvigsak

EFDMEKDDGLSESV
|.|.. .  | | .
eldvdyerwleers

subfamily_Choan-PTP-4_pd Subfamily Choan-PTP-4 2-89 1.2e-09 32.5 In-house 84-177 (297) alignment
Range on Protein: 2-89
Range on HMM: 84-177/297.0
PLSQTVTDFLRLIYDYRISTIVMLNDLSKED--ASSIYWDEANPNIKQPFSM------NVLDTVESEHWTErtLELKHRKNTRIIQHFQFLSWKEV
|||.|| || .|...  . .|||.  | ..       || ... . ..  ..      .. |  .  . ||  |.| .|...| ..| ||||| . 
plsatvddfwtlvaeqdvrvivmvaklqedGrdkcapywpsvvqerlkagdvvveflsstsdefdrvilte..lqliyrsesrvvrhvqflswpdh

subfamily_PTPN6_pd Subfamily PTPN6 3-184 1.4e-27 91.5 In-house 107-302 (306) alignment
Range on Protein: 3-184
Range on HMM: 107-302/306.0
LSQTVTDFLRLIYDYRISTIVMLNDLSKE--DASSIYWDEANPNIKQ-PFSMNVLDTVESEHWTERTLELK---HRKNTRIIQHFQFLSWKEVDSVDFYQ
|..||.|| |....     |||.        .  . || ... . .    |.. ..  . .... |.| ..   . |..| . ...| || . .     .
lettvsdFWrmvwqensrvivmttkevErgkekCarYWPdeeekeeyGkisvtnvseksladYilRelsvskkkkkkeerevfqyhfksWPdhgvpkdpg

TLLDFMNNVTSQQGGDS-----PVLVHCLNGVGRTGVFCVVKMCLDQLEV---EDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMAMSQE
..|||...|...|   .     |..||| .|.|||| | |. . |...|    .  .|. ..|| .|.   ...|  . ||. |..... .  ...
avLdfledvnrkqeeleeaeagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqteqqykfvykaikkyietkkk

subfamily_hpo-7_pd Subfamily hpo-7 3-140 7.6e-11 36.4 In-house 43-186 (263) alignment
Range on Protein: 3-140
Range on HMM: 43-186/263.0
LSQTVTDFLRLIYDYRISTIVMLNDLSKE--DASSIYWDEANPNIKQPFSMNVLDTVESEHWTERTLELKH----RKNTRIIQHFQFLSWKEVDSVDFYQ
| ||.  |.. |   . ...||| |   |  .  | |.     . ..   .||  |   .    .||||      .|.|. ..|...  | |.  .   .
lvqtidkfyqtivqtktevvvmLcDfneegvekcssyfPlekdekqklanvnvcttkvqsdvllktlellstlgeKkkthtvkhysykgWiekndpelar

TLLDFMNNVTSQqggdSPVLVHCLNGVGRTGVFCVVKMCLD----QLE
  |  .. ..       .. ||| .|.||.  | |. .       .|.
eilnilkvarns....kslvvhcstGiGrsaafsvaElvyqkmirsld

0036282 (Phosphotyrosine protein) phosphatases II 4-173 2.9e-26 87.6 In-house 27-164 (174) alignment
Range on Protein: 4-173
Range on HMM: 27-164/174.0
SqtvtdFLRLIYDYRISTIVMLNDLSKED--ASSIYWDEanpnikqpfsmnvldtvesehwtertlelKHRKNTRIIQHFQFLSWKEVDSVDFYQtLLDF
.     |........|.|.|||...   .      || |                             ..   .| . ....| |      |. . ||.|
a.....fwemlkelgittvvmlleekelglykcinywpe.............................lredlerlgiqylylpwpDhgvpdlsi.llef

MNNVTSQQGG--DSPVLVHCLNGVGRTGVFCVVKMCLDQLEvEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYR
.. | . .    . ||||||  ||||||....  ..| .|. |..||....|..||  . .|.|. . |. .| 
vkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtpsQyrflyy

subfamily_Cele-PTP-13_pd Subfamily Cele-PTP-13 4-177 2.4e-14 47.7 In-house 91-267 (281) alignment
Range on Protein: 4-177
Range on HMM: 91-267/281.0
SQTVTDFLRLIYDYRISTIVMLNDLS---KEDASSIYWDEANPNIK-QPFSMNVLDTVESEHWTERTLELKHRKNTRIIQHFQFLSWKEVDSVDFYQTLL
 .| .|| |.|..   ..|||| ..    .| ..  .  .|   .. . .|..  |.   .      |.| .  .||.| |. .  | . .  .  . .|
ketradfwrmiwqenttaivmlcqfletnrekcaeyfprnahcclqfdklsvsyedstvnkslvttrlnlsyegetrlithwlwkewpdwqvpessevml

DFMNNVTSQQggdSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDA-VDVFQIVKALRHD-NFQMIQSLEDYKLCYRILNH
  . .. ..    .| ..||  ||||.| .  |...|. .    .  |. |||  ||       .|.|..| | ...|  
kilrkirars...tppvihcsagvgrsgtlmaveialqsihshftlpdikqivshlrvtgraasvqtlqqymliwkvlld

0044763 (Phosphotyrosine protein) phosphatases II 5-181 9.9e-20 66.4 In-house 35-173 (178) alignment
Range on Protein: 5-181
Range on HMM: 35-173/178.0
QTVTDFLRLIYDYRISTIVMLNDLSK---EDASSIYWDEANpnikqpfsmnvldtvesehwtertlelkhrkntRIIQHFQFLSWKEVDSVDFYQTLLDF
.   |.|.|.... |..||.|..      ..    ...||.                                    .|. .  ... |. .. . ...|
lppaddlellkelgithivnlteelelgflkcdpywpeeag.................................iqylhipipDhgvpdllehflefvef

MNNVTSQQGgdSPVLVHCLNGVGRTGVFCVVKMCLDQlevedAVDVFQIVKALRHDNFqMIQSLEDYKLCYRILNHLMAM
.... ...|  .||||||  ||||.|....  ... .      ........ .|   . .... .... .|..  .|...
ieealdekg..gpvlVHCsaGvgRsgtlvaaylmkkl.....glsleeaielvrerRp.ivpnpgqlrqLyefelrllke

subfamily_Cele-PTP-9_pd Subfamily Cele-PTP-9 5-156 3.8e-12 40.8 In-house 39-198 (255) alignment
Range on Protein: 5-156
Range on HMM: 39-198/255.0
QTVTDFLRLIYDYRISTIVMLNDLSKED--ASSIYWDEANPNIKQPFSMNVLDTVESEHWTERTLEL----KHRKNTRIIQHFQFLSWKEVDSVDFYQTL
 ||  |.. |   . ...||| |.  |.    | |.     . ..   .||  |  | .   ||||.     ..|.|. ..|...  | |  . .  . .
ltvdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdeklkladvnvtttkssadvvlrtleitstlgekkkthtvkhysykGWieknaPelarei

LDFMNNVTSQqggdSPVLVHCLNGVGRTGVFCVVKMCLD----QLEVEDAV--DVFQIVKALRH
|  .  |.       .|.||| .|.||.  | .. .       .|.  ..|  |  .... ||.
lnilkvvrds....ksvvvhCstGiGrsaafvlaelvyqkmirsldttetveldylslleelrs

subfamily_Nvec-PTP-1_pd Subfamily Nvec-PTP-1 6-171 6.9e-18 59.7 In-house 63-232 (239) alignment
Range on Protein: 6-171
Range on HMM: 63-232/239.0
TVTDFLRLIYDYRISTIVMLNDLSKE--DASSIYWDEANPNIKQpFSMNVLDTVESEHWTERTLELKH--RKNTRIIQHFQFLSWKEVDSVDFYQTLLDF
.  || |.... |   ||||  | .        || ..  .  . . . .  |     .  ||. . .  . . | . ...|  | .    ..  ..| .
ssgdfwrmmwqerrcvivmltglieghkkkchqywpdstskycn.lrvtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlgl

MNNVTSQ-QGGDSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLC
  ..| .   |  | ..||  |||||| | |.   | | . . .||.|. |||.| |  .|.|. |.| . 
rrkitkdslpgarpwvihcsagvgrtgaflvidamlrqakkqktvdifnyvkairedrphmvqtseqyvfi

subfamily_Anemone-PTP-1_pd Subfamily Anemone-PTP-1 6-170 7.6e-18 59.5 In-house 64-232 (239) alignment
Range on Protein: 6-170
Range on HMM: 64-232/239.0
TVTDFLRLIYDYRISTIVMLNDLSKE--DASSIYWDEANPNIKQpFSMNVLDTVESEHWTERTLELKH--RKNTRIIQHFQFLSWKEVDSVDFYQTLLDF
.  || |.... |   ||||  | .        || ..  .  . . . .  |     .  ||. . .  . . | . ...|  | .    ..  ..| .
ssgdfwrmmwqerrcvivmltglieghkkkchqywpdstskycn.lrvtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlgl

MNNVTSQ-QGGDSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKL
  ..| .   |  | ..||  |||||| | |.   | | . . .||.|. |||.| |  .|.|. |.| .
rrkitkdslpgarpwvihcsagvgrtgaflvidamlrqakkqktvdifnyvkairedrphmvqtseqyvf

subfamily_Cele-PTP-1_pd Subfamily Cele-PTP-1 6-183 4.4e-14 47.3 In-house 79-261 (290) alignment
Range on Protein: 6-183
Range on HMM: 79-261/290.0
TVTDFLRLIYDYRISTIVMLNDLSKEDAS------SIYWDEA-NPNIK-QPFSMNVLDTVESEHWTERTLELKHRKNTR-IIQHFQFLSWKEVDSVDFYQ
|. .|. .. . ..  .||| . ....|       . |  |. . ..| . ....  . .. .   .|.|..|. ..    ..| .. .|...   .  .
tiekfwwmakqEkvkqvVmlcefeeksantslfaCakYvpesvgeelkfkgltvkCkskekeddvetRelvvkfddeeeftvtHsllkgWnklnvqedtk

TLLDFMNNVTSQQggdSPVLVHCLNGVGRTGVFCVVKMCLDQLE-VEDAVDVFQIVKALRHDNFQMIQSLEDYKLC-YRILnhlMAMSQ
|||. ...|  ..   .||.||| .|. |  ..  ...    .   ...| . ...||||.   ..|.| ...    . |.   . . .
tllsliqkvkask...tpvivHcvdGiSrsAalaaiilgyQkiaetsgsvkledvlkalrkqralaitsalelafvdagiv...llaie

0051082 (Phosphotyrosine protein) phosphatases II 7-174 3.9e-23 77.1 In-house 22-148 (151) alignment
Range on Protein: 7-174
Range on HMM: 22-148/151.0
VTDFLRLIYDYRISTIVMLNDLSKEDASSIYWDEANpnikqpfsmnvldtvesehwtertlelkhrkntRIIQHFQFLSWKEVDSVDFYQTLLDFMNNVT
  |||.|.... |.|||.|...   .    |. |..                                 . . |...|.|.. .  ......|.|.. . 
ladflellkelgiktivnlrseeergycpeylpelg.................................ievlhipildwpdpglplsfdavleflelll

SqqGGDSPVLVHCLNGVGRTGVFCVVKMCLDQlevedaVDVFQIVKALRHDNFQMIQSLEDYKLCYRI
.   .. ||||||  |.||||..... ..| .      |....... .|  .. ..|. . . .... 
d..kkngpvlvHCsaGkgRTGtlvalylmllg......vsleealeeyrlkrpgvvqpnqqflfqlfa

Y_phosphatase3 Tyrosine phosphatase family 50-134 8.7e-06 20.8 Pfam-A 70-146 (164) alignment
Range on Protein: 50-134
Range on HMM: 70-146/164.0
SMNVLDTVES-EHWTERTLELKHRKNTRIIQHFQFLSWKEvdsVDFYQTLLDFMNNvtsQQgGdsPVLVHCLNGVGRTGVFCVVKM
...||.. .. .. ... |. ........ .... .  .|    . |...|. . .   .. |  |||.||  |  ||||.... .
nlpvlkeeaespeelaerlkeaeeaeeamaeayreilede...kkayrkvlealae...ee.g..pvlfHCtaGKDRTGvvaalll

0048076 (Phosphotyrosine protein) phosphatases II 51-178 9.4e-19 63.0 In-house 36-142 (145) alignment
Range on Protein: 51-178
Range on HMM: 36-142/145.0
MnvldtvesehwtertlELKHRKNTRIIQHFQFLSWKEVDSVDFYQTLLDFMNNVTSQQGGDSPVLVHCLNGVGRTGVFCVVKMCLDqlevEDaVDVFQI
.                    .  .| . ....|.|   .  |....||.|.. . . .  . ||||||  ||||||....  ..|     .. |.....
l................tselellerlgiqylylpwpDhgvpdllellleflefieealkeggpvlVHCsaGvgRtgtlvaaylmll....lg.vsleea

VKALRHDNFQMIQSLEDYKLCYRILNHL
.. .|   ...... . .. .|. . .|
lelvrsqrpgavpnpgqlrflyefelel

subfamily_DSP12_pd Subfamily DSP12 52-169 2.5e-08 28.5 In-house 29-140 (155) alignment
Range on Protein: 52-169
Range on HMM: 29-140/155.0
NVLDTVESEHWtertLELKHRKNTRIIQHFQFLSWKEVDSVDFYQTLLDFMNNVTSQqggDSPVLVHCLNGVGRTGVFCVVK-MCLDQLEVEDAVDVFQI
. . .| .|.      | |..|..   .. | |   |.| ...... .||...  ..   .  |||||  || |   ...   |  ..|..|.|... . 
thvlsvikeel....pehklkkgkvstkfiqilDepeediLshldeavdFieealee...egavlvHCqagvSRSvtiviAYlmkkeklslekAlklvke

VKALRHDNFQMIQSLEDYK
.|   . |   .. |  ..
kkpeiepNegFleQLklfe

PTPc_motif_SM00404 59-168 8.1e-10 33.7 In-house 37-137 (140) alignment
Range on Protein: 59-168
Range on HMM: 37-137/140.0
SEHWTertlelKHRKNTRIIQHFqFLSWKEVDSVDFYQTLLDFMNNVTSQQGgdsPVLVHCLNGVGRTGVFCVV-KMCLDQLEVEDAVDVFQIVKALRHD
.  .|      |. .. .|.|       .. . ... . .|||..|.....|    |||||  || |.. ....  |. .||....|.....  .     
evslt......kensgfqilqip.lddnekdklskyldkvldfienaekkgg...kvlVHCqaGvSRSatliiaYlmryrqlslaeayefvkerRpiisp

NFQMIQSLEDY
|.. ...| .|
nlnfvrqLiey

subfamily_DSP11_pd Subfamily DSP11 63-162 6.3e-07 23.5 In-house 66-167 (178) alignment
Range on Protein: 63-162
Range on HMM: 66-167/178.0
TERTLELKHRKNTRIIQHFQFLSWKEVDSVDFYQTLLDFMNNVTS-QQGGDSPVLVHCLNGVGRTGV-FCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQ
|.|  . |. ... .  .  . . .||.. . .... ..... .  ..  |. . ||| .|| |||   |   .  ...| |||...|. ..    .  .
tdryykkkeltdegvkylklncpGhevpkeelvkkfkeavkefleknkdndkligvhCthGvnrtGyliCrylidvegyepedaieafeearGhsleren

MI
 .
yl

subfamily_Cele-PTP-6_pd Subfamily Cele-PTP-6 65-177 3e-14 47.7 In-house 165-275 (307) alignment
Range on Protein: 65-177
Range on HMM: 165-275/307.0
RTLELKHRKNTRIIQHFQFLSWKEVDSvdfYQTLLDFMNNVTSQQGGDSPVLVHCLNGVGRTGVFCVVKMCLDQL-EVEDAVDVFQIVKALRHDNFQMIQ
 ||...  ...| |||.|.  | .       |. |  .| . . ..   ||.|||  ||||.|    . .  |.. . ..  |. ..|. || .    ||
ttlkvdwaqksrtiqhlqwenwpdrgv...pqinltainlleavrydtnpvvvhcsaGvGrsGtivaislvqdkmiaGinckdmkklveelrsqrhyaiq

SLEDYKLCYRILNH
.   |   .|.| .
teaqylylhrvlle

0048179 (Phosphotyrosine protein) phosphatases II 66-173 3.7e-18 61.1 In-house 22-139 (144) alignment
Range on Protein: 66-173
Range on HMM: 22-139/144.0
TLELKHRKNTRI---------------IQHFQFLSWKEVDSVDFYQTLLDFMNNVTSQQGGDSPVLVHCLNGVGRTGVFCVVKMCLdqleVEDaVDVFQI
  .||. . | .               . ....|.|   .  |... ||.|.. . . .  . ||||||  ||||||....  ...    ... ......
lellkklgittvinlteeyepefleregiqylhlpwpDhgvpdllellleflefieealeeggpvlVHCsaGvgRtgtlvaaylmk....klg.lsleea

VKALRHDNFQMIQSLEDYKLCYR
.. .|  ....... . .. ...
lalvrsrrpgavpnpgqlrfLle

0038934 (Phosphotyrosine protein) phosphatases II 66-153 2.4e-10 35.9 In-house 69-157 (194) alignment
Range on Protein: 66-153
Range on HMM: 69-157/194.0
TLELKHRKN-TRIIQHFQFLSWKEVDSVDFYQTLLDFMNNVTSQqGGDSPVLVHCLNGVGRTGVFCVVKMCL-DQLEVEDAVDVFQIVKA
. . .. ..    . ...| .  .| | . ... ||... ....   .  |.|||  |.||||....  .    .. .|.|.. |.... 
yYdpeefekagieylklpfpddgtvPsleillrfldlvdeflne.dpggvvaVHCkaGlgRtGtlvaaYLiyrlgmsaeeAialfrekRp

subfamily_Cele-PTP-7_pd Subfamily Cele-PTP-7 72-175 2.3e-09 31.1 In-house 184-282 (302) alignment
Range on Protein: 72-175
Range on HMM: 184-282/302.0
RKNTRIIQHFQFLSWKEVDSVDFYQTLLDFMNNVTSQQggdSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSleDYKLC
.|  . .. ..| .| .  . .  .| || ..   | .     ||||| .|||||| .  .|  ..    ..  |. .||. .|.  .  .|.  . .| 
kkvkktvdilafsawpdhGapkeaytaldilkfcesyk...knvlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqd..eqqli

YRIL
| .|
ylll

subfamily_Cele-PTP-18_pd Subfamily Cele-PTP-18 73-176 1.5e-08 28.7 In-house 183-285 (305) alignment
Range on Protein: 73-176
Range on HMM: 183-285/305.0
KNTRIIQHFQFLSWKEVDSVDFYQTLLDFMNNVTSQQGgdsPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVD-VFQIVKALRHDNFQMIQSLEDYKLC
...| ..|. .  | .       ...|.....  . .|   |. |||  |.||||   ...  ||||   . ..   .|.. .| .  . ||. ..| . 
ekarkvthyhwidwpdrgvpaadlailellekarpskg...pivvhcsagigrtgsvvmleyildqllagqiiedtdkilqkireqrnnsiqtdaqylfv

YRIL-N
.... |
hqviln

subfamily_DSP15_pd Subfamily DSP15 73-169 1.7e-08 28.7 In-house 37-136 (151) alignment
Range on Protein: 73-169
Range on HMM: 37-136/151.0
KNTRIIQH--FQFLSWKEVDSVDFYQTLLDFMNNVTSQQGGDSPVLVHCLNGVGRTGVFCVVK-MCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYK
 . .....  ..... ..  |... . . . .. . . .  .  |||||| || |    .|.  |   .|. .||..| .  ... . ||   . |..|.
nakkllkdieYkciaasDtpsaklskffkesvefihkcRlkeenvlvhClaGvsRsvtlvvaYlmtvtelnwrdalevikaaRsvanPnfGfkrqlkeye





DSPc Dual specificity phosphatase, catalytic domain 74-168 2.3e-09 32.2 Pfam-A 36-130 (133) alignment
Range on Protein: 74-168
Range on HMM: 36-130/133.0
NTRIIQHFQFL--SWKEVDSVDFYQTLLDFMNNVtsqQGGDSPVLVHCLNGVGRTGVFCVV-KMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDY
..  |....      .| . ... . . .|....   .     |||||  |. |.. ....  |. ..|....|.....  .     |.. ...| .|
kkseieylripvedetetkiskeleeavefieka...eqkgkkvlVHCqaGisRSatliiaYlmktknlslneAyefvkerrskispnagflrqLley

DSPc Dual specificity phosphatase, catalytic domain 74-168 2.3e-09 32.2 In-house 36-130 (133) alignment
Range on Protein: 74-168
Range on HMM: 36-130/133.0
NTRIIQHFQFL--SWKEVDSVDFYQTLLDFMNNVtsqQGGDSPVLVHCLNGVGRTGVFCVV-KMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDY
..  |....      .| . ... . . .|....   .     |||||  |. |.. ....  |. ..|....|.....  .     |.. ...| .|
kkseieylripvedetetkiskeleeavefieka...eqkgkkvlVHCqaGisRSatliiaYlmktknlslneAyefvkerrskispnagflrqLley

subfamily_Cele-PTP-4_pd Subfamily Cele-PTP-4 75-179 1.1e-12 42.0 In-house 180-285 (302) alignment
Range on Protein: 75-179
Range on HMM: 180-285/302.0
TRIIQHFQFLSWKEVDSVDFYQTLLDFMNNV-TSQQGGDSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYR
. ...   .  ||.    . | .|   . .| .... .|.....   ||.|| |.| .. . ...|. .... . .|||..| .  ....||. |   |.
svlanvyvltnWkqkkvpvkyaeliktaakvfakkikadentvivSknGaGRagafltlavaveklqkgkepnikeivksiRsqRpravdslkQyvslyi

ILNHLM
.|. ..
alllyi

subfamily_Cele-PTP-11_pd Subfamily Cele-PTP-11 76-179 2.9e-09 31.1 In-house 176-276 (312) alignment
Range on Protein: 76-179
Range on HMM: 176-276/312.0
RIIQHFQFLSWKEVDSVDFYQTLLDFMNNVTSQQggdSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRIL
  ..|.|. || .    |  .| | ..  |  ..    ||. ||  |||||| .....  .  |      .| ..   ||.|  . .. . .|  . |..
sklnhyqwaswpdhgmpdscdtalrllsavkkdk...kpviahcsagvgrtgtlaliesmiaalrhprkqnvkdsfvllrkdrarsvrvfpqyvyalrcv

NHLM
 ...
lefl

PTPc_DSPc_SM00012 78-176 8e-26 85.7 In-house 2-104 (105) alignment
Range on Protein: 78-176
Range on HMM: 2-104/105.0
IQHFQFLSWKEVDSVDFYQTLLDFMNNVTSQQGGD---SPVLVHCLNGVGRTGVFCVVKMCLDQLEVE-DAVDVFQIVKALRHDNFQMIQSLEDYKLCYR
..|.....|..    .  . .|.....| ...      .||.||| .||||||.|... ..|.||| | . ||.|||||.||.   .|.|..|.|  .||
vkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylflyr

ILN
.|.
all

subfamily_DSP19_pd Subfamily DSP19 82-168 2.9e-07 24.9 In-house 62-146 (152) alignment
Range on Protein: 82-168
Range on HMM: 62-146/152.0
QFLSWKEVDSVDFYQTLLDFMNNVTSQQggdSPVLVHCLNGVGRTGVFCVVKM-CLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDY
. |  .| | ...... |||.... |..     |||||  || |.  . .  .    .|..|.|... . ..   . |   |. |..|
eilDlpetdllsylkealdFieearskd...gavlvHCnAGvSRsasvviaylmkkeelsleealelvrearpcikPneGFikqLkey

subfamily_DSP6_pd Subfamily DSP6 88-169 5.3e-08 26.5 In-house 69-151 (158) alignment
Range on Protein: 88-169
Range on HMM: 69-151/158.0
EVDSVDFYQTLLDFMNNVTSQQGGDSPVLVHCLNGVGRTGVFCVV-KMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYK
.. | .. . . . .. .   .  .| |||||| |. |.   ..   |   .| ..|| |. .  |.    ||.... | |. 
dhlsqnlakffPeaiefidearskkskvlvhClaGisrsvtvtlaylmkklalslndaydlvkkrksnisPnfnfmgqlldfe

subfamily_DSP14_pd Subfamily DSP14 89-168 6.2e-06 20.2 In-house 63-140 (157) alignment
Range on Protein: 89-168
Range on HMM: 63-140/157.0
VDSVDFYQTLLDFMNNVTSQQGGdspVLVHCLNGVGRTGVFCVVK-MCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDY
.. ......  | ...|. ..|    .|||| .|| |   .|..  |   .|  ..|  . . .. . . |    . | ||
aklakhfdevadkieevkkkggk...tlvhCvaGvSRSAslclaylmkyeklsLreayklvksaRpiirPNvGFwkqlidy

subfamily_DSP1_pd Subfamily DSP1 90-169 6.5e-09 30.1 In-house 76-153 (163) alignment
Range on Protein: 90-169
Range on HMM: 76-153/163.0
DSVDFYQTLLDFMNNVTSQQGgdsPVLVHCLNGVGRTGVFCVVK-MCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYK
|    ... ..|...|....|    ||.||  |. |   .|..  |  .....|.| |  . .... . |.  ...| .|.
dislvfeeviefidevkkknG...kvlihCqaGisRsstlclaylmktkrvsleeafdfvkqrRsiisPnagFvlqLlnye

subfamily_Fungi-PTP1_pd Subfamily Fungi-PTP1 98-183 2e-09 31.7 In-house 247-348 (350) alignment
Range on Protein: 98-183
Range on HMM: 247-348/350.0
LLDF-MNNVTSQQGGDSPVLVHCLNGVGRTGVFCVVKMCLDQLEV-------------E-DAVD-VFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMAM
|.|  . .  ...   ||.||||  ||||||... . . | ..|.                  | ...||. ||.   .|.|.|. .  .|  | .. |.
liddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlisiivnelrkqrismvqnldqfifiYeallfyfaL

SQ
..
rk

subfamily_Fungi-PTP2_pd Subfamily Fungi-PTP2 98-180 2.4e-08 27.7 In-house 250-345 (349) alignment
Range on Protein: 98-180
Range on HMM: 250-345/349.0
LLDFMNN-VTSQQGGDSPVLVHCLNGVGRTGVFCVVKMCLDQLE--VEDAV----------DVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMA
|.| ..     ..   |..||||  | |||||.. . . |. ||   .. .           .. ||  ||   ..|.| | ..  .|  | . .|
liddlfarlyldtdqlstllvhcsaGcGrtGvlvtldlllsileplqnesnkiklqallkDlisiivnelrkqrismvqnlaqfiaiyealLkyfa

PTEN_1 100-168 3.6e-06 21.9 In-house 119-188 (196) alignment
Range on Protein: 100-168
Range on HMM: 119-188/196.0
DFMNNVTSQQGgDSPVLVHCLNGVGRTGV-FCVVKMCLDQLEVEDAVDVFQIVK-ALRHDNFQMIQSLEDY
.|.. . |..     |||||  |.||.|.  .   | . .| ...|.. ...   . .  .... . || .
sfiewllsdpn.gnvVlVHCkaGlgRsGtvvaayLmykgkltadeAlelvrekRppgapnspsqerlleyf

subfamily_Choan-PTP-4_pd Subfamily Choan-PTP-4 103-174 2e-11 38.3 In-house 219-290 (297) alignment
Range on Protein: 103-174
Range on HMM: 219-290/297.0
NNVTSQQGGDSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRI
. . ...  . ..||||  ||||.||    .. |..|  .   ||  |.. ||.   ...|.|| ..|.| .
eslraemprnayllvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqtleqfellyda

subfamily_CG42327_pd Subfamily CG42327 107-177 3e-14 47.4 In-house 242-313 (319) alignment
Range on Protein: 107-177
Range on HMM: 242-313/319.0
SQQGGDSPVLVHCLNGVGRTGVFCVVKMCLDQLEVE-DAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNH
...    |. ||| .||||||.     . . .||    .||. |.|  .|.|  . ... | |.. |..|  
gtresqGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefiykvlse

subfamily_PRL_pd Subfamily PRL 108-170 2.4e-06 21.7 In-house 86-147 (151) alignment
Range on Protein: 108-170
Range on HMM: 86-147/151.0
QQGGDSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVfqiVKALRHD--NFQMIQSLEDYKL
.. ..| | |||. |.||. |. .. .  . .. ||||..   ..  |..  | . .. ||.|| 
keepkstvavhcvaGlGraPvlvalalieaGmkyedavef...irekrrgainskqlkflekyka

subfamily_Cele-PTP-14_pd Subfamily Cele-PTP-14 112-174 5.6e-08 26.7 In-house 223-285 (310) alignment
Range on Protein: 112-174
Range on HMM: 223-285/310.0
DSPVLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRI
  |..|||  |..|..| . .|. .|.|.  . ||. ...  |...... ||.  .| .  |.
hgpcvvhcsagkdrlyvvvalklkidkldrglkvdaeevktellksraiciqtelqyliidrv

subfamily_Urchin-PTP-4_pd Subfamily Urchin-PTP-4 115-177 5.6e-19 62.8 In-house 321-383 (392) alignment
Range on Protein: 115-177
Range on HMM: 321-383/392.0
VLVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNH
.||||| | |||||||    |. |.   |.||.|| || || | .|..|. |.| . | . . 
ilvhclsgagrtgvfctameciaqiaegdsvdifqtvkilradrmqfvqteeeyafvydvire

subfamily_Sponge-PTP-7_pd Subfamily Sponge-PTP-7 116-168 9.3e-07 23.2 In-house 2-54 (69) alignment
Range on Protein: 116-168
Range on HMM: 2-54/69.0
LVHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDY
.|||  | |||| |  . . . ..  |  ||.|  |. .|     |.    .|
vvhcssgtgrtgtfiaimvemarikseklvdifnnvqymrkcrpmmvmneiey

subfamily_Sponge-PTP7_pd Subfamily Sponge-PTP7 117-170 7.9e-07 23.3 In-house 2-55 (69) alignment
Range on Protein: 117-170
Range on HMM: 2-55/69.0
VHCLNGVGRTGVFCVVKMCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKL
|||  | |||| |  . . . ..  |  ||.|  |. .|     |.   ..| .
vhcssGtGrtGtfiaimvemarikseklvdifnnvqymrkcrpmmvmneneymf