Gene SpurPTP-sf1-17 in Strongylocentrotus purpuratus

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family PTP
Subfamily SpurPTP-sf1
Protein sequence
ID Type Fasta BLAST phosphatome Note
SpurP094_AA protein Get Run
SpurP094_AA_0-47 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
Y_phosphatase Protein-tyrosine phosphatase 1-42 4.2e-09 31.5 Pfam-A 192-233 (235) alignment 
Range on Protein: 1-42
Range on HMM: 192-233/235.0
MCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRIL
..|.||| |. |||.|||| ||.  ..|.|||| |. .|...
illeqleaeeevdvlqivkelRkqRpgmvqsleqYiflykai
Y_phosphatase Protein-tyrosine phosphatase 1-42 4.2e-09 31.5 In-house 192-233 (235) alignment 
Range on Protein: 1-42
Range on HMM: 192-233/235.0
MCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRIL
..|.||| |. |||.|||| ||.  ..|.|||| |. .|...
illeqleaeeevdvlqivkelRkqRpgmvqsleqYiflykai
DSPc_SM00195 1-46 1.5e-08 29.7 In-house 217-262 (263) alignment 
Range on Protein: 1-46
Range on HMM: 217-262/263.0
MCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLM
..|..|| |. ||.|.|||.||.  ..|.|.|| |. .|... ...
iilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi
PTPc_SM00194 1-46 1.5e-08 29.7 In-house 217-262 (263) alignment 
Range on Protein: 1-46
Range on HMM: 217-262/263.0
MCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLM
..|..|| |. ||.|.|||.||.  ..|.|.|| |. .|... ...
iilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi
0050432 (Phosphotyrosine protein) phosphatases II 1-46 3.6e-08 28.6 In-house 254-299 (308) alignment 
Range on Protein: 1-46
Range on HMM: 254-299/308.0
MCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLM
..|.||| |  ||||..|| ||.   .|.|..| |...||.| ...
llleqlekeggvdvfeavkklReqRpgmvqtpeqylflyralleyl
0051299 (Phosphotyrosine protein) phosphatases II 1-45 9e-08 27.4 In-house 241-285 (288) alignment 
Range on Protein: 1-45
Range on HMM: 241-285/288.0
MCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHL
..|.||| |  |||...|| ||.  ..|.|..| |...|..| ..
llleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyealley
0046845 (Phosphotyrosine protein) phosphatases II 1-46 1.2e-07 26.9 In-house 226-274 (284) alignment 
Range on Protein: 1-46
Range on HMM: 226-274/284.0
MCLDQLEVED---AVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLM
..|.||| |.    |||...|| ||   ..|.|.|| |...|..| ...
llleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleyl
PTPc_DSPc_SM00012 1-43 2.7e-07 26.1 In-house 61-104 (105) alignment 
Range on Protein: 1-43
Range on HMM: 61-104/105.0
MCLDQLEVE-DAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILN
..|.||| | . ||.|||||.||.   .|.|..|.|  .||.|.
illqqleketkevdifqivkelrkqRpgmvqteeqylflyrall
subfamily_PTPN9_pd Subfamily PTPN9 1-42 7.7e-07 23.4 In-house 245-286 (297) alignment 
Range on Protein: 1-42
Range on HMM: 245-286/297.0
MCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRIL
.||..|| .. |||.. || ||     .||  | |..||  .
iclsrleevgtvdvvetvkllrtqrafsiqtpeqyefcylav
0047943 (Phosphotyrosine protein) phosphatases II 1-44 9.2e-07 24.1 In-house 227-270 (273) alignment 
Range on Protein: 1-44
Range on HMM: 227-270/273.0
MCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNH
..||||| |  |||...|| ||   . |.|..| |...|..| .
llldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyealle
0036941 (Phosphotyrosine protein) phosphatases II 1-45 1.1e-06 23.6 In-house 229-276 (297) alignment 
Range on Protein: 1-45
Range on HMM: 229-276/297.0
MCLDQLE---VEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHL
..|.|||    |  ||....|| ||.  ....|.|| |. .|..| .|
lmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallel
0040438 (Phosphotyrosine protein) phosphatases II 1-46 3.4e-06 22.0 In-house 231-276 (317) alignment 
Range on Protein: 1-46
Range on HMM: 231-276/317.0
MCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLM
..|.||| |  |||...|| ||.   ...|..| |. .|..|....
lmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleyl
subfamily_Sponge-PTP10_pd Subfamily Sponge-PTP10 1-46 7.3e-06 20.2 In-house 233-278 (287) alignment 
Range on Protein: 1-46
Range on HMM: 233-278/287.0
MCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLM
. ... . | ..||||..|  |    ...|  | ||  . |. . .
ttinkckteGviDvfqvlksqriqkpgsvqtveqykfindivleyl
subfamily_Sponge-PTP8_pd Subfamily Sponge-PTP8 2-56 1.4e-10 35.8 In-house 239-293 (305) alignment 
Range on Protein: 2-56
Range on HMM: 239-293/305.0
CLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMAMSQENTLQS
 |..|. |. ||||...|.||.   .|.|.|. |  .. .|. |.   . . . |
alerlkkEevvdvfevlkqlRskrmkmvqtldqYvflhdaldelitcgdtsiigs
subfamily_CG7180_pd Subfamily CG7180 2-47 2.7e-10 34.4 In-house 246-291 (296) alignment 
Range on Protein: 2-47
Range on HMM: 246-291/296.0
CLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMA
.|...| |. ||||. || ||..  |.... |.|| .| .|.. . 
nlelvekeeevdvFeavktlrrsRpqLvenveeYkyiYdvlleavl
subfamily_PTPRD_pd Subfamily PTPRD 2-54 4e-10 34.0 In-house 237-289 (564) alignment 
Range on Protein: 2-54
Range on HMM: 237-289/564.0
CLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMAMSQENTL
.|.... |. ||..|.|||||..   |.|. | |  ....... .|. ...  
mlerikeektvDiyqyvkalrkqRnamVqteeQYiFiheailealacgnteve
subfamily_Urchin-PTP-7_pd Subfamily Urchin-PTP-7 2-46 1.6e-09 32.1 In-house 235-279 (315) alignment 
Range on Protein: 2-46
Range on HMM: 235-279/315.0
CLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLM
 |||.|.|.|.||..... .|.   .|.|..| |.. | .|   .
vldqaeaenaidvynfitgvrqnrikmvqvaeqyqfiydalletf
subfamily_Anemone-PTP-5_pd Subfamily Anemone-PTP-5 2-58 2.2e-09 31.8 In-house 239-296 (319) alignment 
Range on Protein: 2-58
Range on HMM: 239-296/319.0
CLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMAMSQ-ENTLQSTQ
 |.... | ..|||..|. ||     |.|  | ||..| .| . . . . |  .|  .
mlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyealleaveagdteievqdlr
subfamily_Sponge-PTP9_pd Subfamily Sponge-PTP9 2-50 3.8e-09 30.7 In-house 249-297 (301) alignment 
Range on Protein: 2-50
Range on HMM: 249-297/301.0
CLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMAMSQ
 |.|   |  |||||..||.|.    ... || |   | ...  ... .
glEQckaegVVdvfqvtkavrrskpgaVtTLeqytsiydvidmylqlns
subfamily_Urchin-PTP-5_pd Subfamily Urchin-PTP-5 2-54 5.2e-09 30.6 In-house 240-291 (297) alignment 
Range on Protein: 2-54
Range on HMM: 240-291/297.0
CLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMaMSQENTL
.. . . |..||.|..|| ||..  ...|  |.||. | ...  . .|..  .
vvaeakrekevdifglvkklrqerpylvqtkeqykfvyvavleal.lsedtri
subfamily_Urchin-PTP-2_pd Subfamily Urchin-PTP-2 2-45 8.5e-09 29.2 In-house 394-437 (440) alignment 
Range on Protein: 2-45
Range on HMM: 394-437/440.0
CLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHL
||.||. . |.|||| .. ||    ... .| || |||..| | 
cleqlnndgaidvfqnlrllrlsrpnfvptltdyllcykllthh
subfamily_Urchin-PTP-1_pd Subfamily Urchin-PTP-1 2-61 1.2e-08 29.2 In-house 233-290 (315) alignment 
Range on Protein: 2-61
Range on HMM: 233-290/315.0
CLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMamSQENTLQSTQEFD
...|.. ...||||..|| || .  ...|. |.| . | ..   .     |||     | 
vvaqikrtrsvdvfnfvknlrakrpylvqteeeyafiydavledl..lwrntlilvihft
subfamily_Urchin-PTPRB-like_pd Subfamily Urchin-PTPRB-like 2-48 1.6e-08 29.0 In-house 235-281 (288) alignment 
Range on Protein: 2-48
Range on HMM: 235-281/288.0
CLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMAM
 .|..| || .||. .|. ||.  ....| |. |  .|..| .|.  
lidaveeedyiDvagtvaklRkqRallvqtlkqYefiyevllsliee
subfamily_Urchin-PTP-4_pd Subfamily Urchin-PTP-4 2-44 6e-08 26.5 In-house 341-383 (392) alignment 
Range on Protein: 2-44
Range on HMM: 341-383/392.0
CLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNH
|. |.   |.||.|| || || | .|..|. |.| . | . . 
ciaqiaegdsvdifqtvkilradrmqfvqteeeyafvydvire
subfamily_PTPN5_RR_pd Subfamily PTPN5_RR 2-45 5.3e-07 24.0 In-house 224-267 (274) alignment 
Range on Protein: 2-45
Range on HMM: 224-267/274.0
CLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHL
.. ||. |  |||..||  || |   |.|. | |.| .|.| . 
avrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralcly
subfamily_Sponge-PTP11_pd Subfamily Sponge-PTP11 2-44 8.6e-07 23.1 In-house 239-281 (290) alignment 
Range on Protein: 2-44
Range on HMM: 239-281/290.0
CLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNH
 ... . |  .||||..| .|    ...|. . |.. ..|. .
tinkcktegvidvfqvlksqRiqkpgsvqtvqqyqgifqivlt
subfamily_Choan-PTP-2_pd Subfamily Choan-PTP-2 2-46 4.6e-06 20.8 In-house 220-264 (270) alignment 
Range on Protein: 2-46
Range on HMM: 220-264/270.0
CLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLM
..  || .  ||| .|...||.|  ...|  | |.. |. . . .
avrlLeetkkvdvlaiieelRkdRmalvqhpeqyeflykavveya
subfamily_Sponge-PTP6_pd Subfamily Sponge-PTP6 2-69 8.7e-06 19.4 In-house 235-300 (439) alignment 
Range on Protein: 2-69
Range on HMM: 235-300/439.0
CLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMamSQENTLQSTQEFDMEKDDGLS
.|.|| .|. ||.  ||| ||..  ||.|.| .| . |  .   .     ..  . .||  | . |.|
aleqlklenkvdikgivkvlrkqrkqmvqalcqyvfiynavledi..vyGdiavtidefkkefnagfs
subfamily_PTPRA_pd Subfamily PTPRA 3-46 6.1e-10 33.5 In-house 252-295 (330) alignment 
Range on Protein: 3-46
Range on HMM: 252-295/330.0
LDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLM
|.... |  ||||..|| ||    ||.|..| |...|..| .  
lervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvlleyy
subfamily_Anemone-PTP-2_pd Subfamily Anemone-PTP-2 3-47 6.8e-10 33.7 In-house 247-291 (298) alignment 
Range on Protein: 3-47
Range on HMM: 247-291/298.0
LDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMA
|.... |  |||||.||.||..  ...|. |.|. .| .  . ..
lervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavleald
subfamily_Ptp69D_pd Subfamily Ptp69D 3-50 7e-10 33.5 In-house 243-290 (307) alignment 
Range on Protein: 3-50
Range on HMM: 243-290/307.0
LDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMAMSQ
|.||. || ||.|..|| ||..   ..|||| |. .|| |   . ...
lqqlkaedkvdifetvkdLrsqRnllvqsleqYvflyralldyssygd
subfamily_Nvec-PTP-2_pd Subfamily Nvec-PTP-2 3-50 2.3e-09 31.8 In-house 199-246 (250) alignment 
Range on Protein: 3-50
Range on HMM: 199-246/250.0
LDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMAMSQ
|..|. |  ||||...|.||.|  ....||| |  .|.|. . .  ..
lerlkkekvvdvfkvikvlrkdrphavesleqyvfvyeiilkaldsve
subfamily_Anemone-PTP-6_pd Subfamily Anemone-PTP-6 3-52 4.5e-09 30.8 In-house 237-286 (318) alignment 
Range on Protein: 3-52
Range on HMM: 237-286/318.0
LDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMAMSQEN
|.... |  |||||.|| ||.    |.|  . |...| .|   .|  . .
lerikaealvDvfqtvkqlreqrnlmvqtedqyefiydvllealasgdte
subfamily_Urchin-PTP-3_pd Subfamily Urchin-PTP-3 3-50 4.8e-08 27.5 In-house 245-292 (325) alignment 
Range on Protein: 3-50
Range on HMM: 245-292/325.0
LDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMAMSQ
|...  |  ||.|. || ||.|  .|... . | |.|  |   .  ..
lakvieesrvdifgfvkklrkdrpsmvetvdqyiliyealveaymsgn
subfamily_PTPRK_pd Subfamily PTPRK 3-42 6.4e-08 26.8 In-house 234-273 (314) alignment 
Range on Protein: 3-42
Range on HMM: 234-273/314.0
LDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRIL
|| .| |. ||||..||.||     |..  | ||..| ..
ldmieregvvdvfnavktlrsrkvnmveteeqykfiydvi
subfamily_Urchin-PTP-6_pd Subfamily Urchin-PTP-6 3-45 2.8e-07 24.0 In-house 233-275 (515) alignment 
Range on Protein: 3-45
Range on HMM: 233-275/515.0
LDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHL
. . .  ..||||..|. .| .  ...|  |.| . | ..   
vahakttrmvdvfnfvtnirqkrpylvqtqeqyafiygavled
subfamily_Urchin-PTP-8_pd Subfamily Urchin-PTP-8 3-49 5.1e-07 24.5 In-house 212-260 (284) alignment 
Range on Protein: 3-49
Range on HMM: 212-260/284.0
LDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILN--HLMAMS
||... |. |||...|. || .  ...|.| .||..|  |   ||.. |
ldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleehlfghs
subfamily_PTPRG_pd Subfamily PTPRG 3-58 5.7e-07 23.1 In-house 244-298 (563) alignment 
Range on Protein: 3-58
Range on HMM: 244-298/563.0
LDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMAmSQENTLQSTQ
| |.. |.||.||...| .|     ..|. |.|   . .|  ..| |.|. |...|
lkqiqqenavnvfgflkhiraqRnflvqteEqYiflhdalleaia.sketellaeq
subfamily_Urchin-PTPRA_pd Subfamily Urchin-PTPRA 3-49 6.1e-07 24.0 In-house 248-296 (319) alignment 
Range on Protein: 3-49
Range on HMM: 248-296/319.0
LDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRIL-N-HLMAMS
||... |. |||...|. || .  ...|.| .||..|  | . ||.. |
ldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleehlfghs
subfamily_Sponge-PTP5_pd Subfamily Sponge-PTP5 3-42 2e-06 21.9 In-house 223-262 (283) alignment 
Range on Protein: 3-42
Range on HMM: 223-262/283.0
LDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRIL
....  |  ||||..|| .| .   ..|.|. ||| . . 
vkdaltesvvdvfavvkimreqrmmavqtldqyklvhelv
subfamily_PTPRB_pd Subfamily PTPRB 3-51 3.5e-06 21.3 In-house 242-290 (293) alignment 
Range on Protein: 3-51
Range on HMM: 242-290/293.0
LDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMAMSQE
|...| || ||.| || .||.. ....|. ..|   .. . .|.  ..|
lqaieeedyvdifgivaelReeRnllvqtekqYifihqcvldllrkkee
subfamily_PTPN12_pd Subfamily PTPN12 4-50 1.6e-06 22.2 In-house 235-281 (290) alignment 
Range on Protein: 4-50
Range on HMM: 235-281/290.0
DQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMAMSQ
 .  ... .|||..|  ||..   ..|. | |.| |. . .|.  . 
kaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelvqkel
AAA_PrkA PrkA AAA domain 9-68 4.8e-06 11.7 Pfam-A 217-276 (358) alignment 
Range on Protein: 9-68
Range on HMM: 217-276/358.0
EDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMAMSQENTLQSTQEFDMEKDDGL
|.  |...   || . |  ... .| .|   ..| .|... ||....||... . . ||.
endpdaysysGalnranrGllefvemfkadikvlhplltatqegnyksteklslipfdgi