Gene SpurPTP-sf1-17 in Strongylocentrotus purpuratus

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family PTP
Subfamily SpurPTP-sf1
Protein sequence
ID Type Fasta BLAST phosphatome Note
SpurP094_AA protein Get Run
SpurP094_AA_0-47 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
Y_phosphatase Protein-tyrosine phosphatase 1-42 4.2e-09 31.5 Pfam-A 192-233 (235) alignment
Range on Protein: 1-42
Range on HMM: 192-233/235.0
MCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRIL
..|.||| |. |||.|||| ||.  ..|.|||| |. .|...
illeqleaeeevdvlqivkelRkqRpgmvqsleqYiflykai

Y_phosphatase Protein-tyrosine phosphatase 1-42 4.2e-09 31.5 In-house 192-233 (235) alignment
Range on Protein: 1-42
Range on HMM: 192-233/235.0
MCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRIL
..|.||| |. |||.|||| ||.  ..|.|||| |. .|...
illeqleaeeevdvlqivkelRkqRpgmvqsleqYiflykai

DSPc_SM00195 1-46 1.5e-08 29.7 In-house 217-262 (263) alignment
Range on Protein: 1-46
Range on HMM: 217-262/263.0
MCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLM
..|..|| |. ||.|.|||.||.  ..|.|.|| |. .|... ...
iilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi

PTPc_SM00194 1-46 1.5e-08 29.7 In-house 217-262 (263) alignment
Range on Protein: 1-46
Range on HMM: 217-262/263.0
MCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLM
..|..|| |. ||.|.|||.||.  ..|.|.|| |. .|... ...
iilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi

0050432 (Phosphotyrosine protein) phosphatases II 1-46 3.6e-08 28.6 In-house 254-299 (308) alignment
Range on Protein: 1-46
Range on HMM: 254-299/308.0
MCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLM
..|.||| |  ||||..|| ||.   .|.|..| |...||.| ...
llleqlekeggvdvfeavkklReqRpgmvqtpeqylflyralleyl

0051299 (Phosphotyrosine protein) phosphatases II 1-45 9e-08 27.4 In-house 241-285 (288) alignment
Range on Protein: 1-45
Range on HMM: 241-285/288.0
MCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHL
..|.||| |  |||...|| ||.  ..|.|..| |...|..| ..
llleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyealley

0046845 (Phosphotyrosine protein) phosphatases II 1-46 1.2e-07 26.9 In-house 226-274 (284) alignment
Range on Protein: 1-46
Range on HMM: 226-274/284.0
MCLDQLEVED---AVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLM
..|.||| |.    |||...|| ||   ..|.|.|| |...|..| ...
llleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleyl

PTPc_DSPc_SM00012 1-43 2.7e-07 26.1 In-house 61-104 (105) alignment
Range on Protein: 1-43
Range on HMM: 61-104/105.0
MCLDQLEVE-DAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILN
..|.||| | . ||.|||||.||.   .|.|..|.|  .||.|.
illqqleketkevdifqivkelrkqRpgmvqteeqylflyrall

subfamily_PTPN9_pd Subfamily PTPN9 1-42 7.7e-07 23.4 In-house 245-286 (297) alignment
Range on Protein: 1-42
Range on HMM: 245-286/297.0
MCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRIL
.||..|| .. |||.. || ||     .||  | |..||  .
iclsrleevgtvdvvetvkllrtqrafsiqtpeqyefcylav

0047943 (Phosphotyrosine protein) phosphatases II 1-44 9.2e-07 24.1 In-house 227-270 (273) alignment
Range on Protein: 1-44
Range on HMM: 227-270/273.0
MCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNH
..||||| |  |||...|| ||   . |.|..| |...|..| .
llldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyealle

0036941 (Phosphotyrosine protein) phosphatases II 1-45 1.1e-06 23.6 In-house 229-276 (297) alignment
Range on Protein: 1-45
Range on HMM: 229-276/297.0
MCLDQLE---VEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHL
..|.|||    |  ||....|| ||.  ....|.|| |. .|..| .|
lmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallel

0040438 (Phosphotyrosine protein) phosphatases II 1-46 3.4e-06 22.0 In-house 231-276 (317) alignment
Range on Protein: 1-46
Range on HMM: 231-276/317.0
MCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLM
..|.||| |  |||...|| ||.   ...|..| |. .|..|....
lmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleyl

subfamily_Sponge-PTP10_pd Subfamily Sponge-PTP10 1-46 7.3e-06 20.2 In-house 233-278 (287) alignment
Range on Protein: 1-46
Range on HMM: 233-278/287.0
MCLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLM
. ... . | ..||||..|  |    ...|  | ||  . |. . .
ttinkckteGviDvfqvlksqriqkpgsvqtveqykfindivleyl

subfamily_Sponge-PTP8_pd Subfamily Sponge-PTP8 2-56 1.4e-10 35.8 In-house 239-293 (305) alignment
Range on Protein: 2-56
Range on HMM: 239-293/305.0
CLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMAMSQENTLQS
 |..|. |. ||||...|.||.   .|.|.|. |  .. .|. |.   . . . |
alerlkkEevvdvfevlkqlRskrmkmvqtldqYvflhdaldelitcgdtsiigs

subfamily_CG7180_pd Subfamily CG7180 2-47 2.7e-10 34.4 In-house 246-291 (296) alignment
Range on Protein: 2-47
Range on HMM: 246-291/296.0
CLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMA
.|...| |. ||||. || ||..  |.... |.|| .| .|.. . 
nlelvekeeevdvFeavktlrrsRpqLvenveeYkyiYdvlleavl

subfamily_PTPRD_pd Subfamily PTPRD 2-54 4e-10 34.0 In-house 237-289 (564) alignment
Range on Protein: 2-54
Range on HMM: 237-289/564.0
CLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMAMSQENTL
.|.... |. ||..|.|||||..   |.|. | |  ....... .|. ...  
mlerikeektvDiyqyvkalrkqRnamVqteeQYiFiheailealacgnteve

subfamily_Urchin-PTP-7_pd Subfamily Urchin-PTP-7 2-46 1.6e-09 32.1 In-house 235-279 (315) alignment
Range on Protein: 2-46
Range on HMM: 235-279/315.0
CLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLM
 |||.|.|.|.||..... .|.   .|.|..| |.. | .|   .
vldqaeaenaidvynfitgvrqnrikmvqvaeqyqfiydalletf

subfamily_Anemone-PTP-5_pd Subfamily Anemone-PTP-5 2-58 2.2e-09 31.8 In-house 239-296 (319) alignment
Range on Protein: 2-58
Range on HMM: 239-296/319.0
CLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMAMSQ-ENTLQSTQ
 |.... | ..|||..|. ||     |.|  | ||..| .| . . . . |  .|  .
mlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyealleaveagdteievqdlr

subfamily_Sponge-PTP9_pd Subfamily Sponge-PTP9 2-50 3.8e-09 30.7 In-house 249-297 (301) alignment
Range on Protein: 2-50
Range on HMM: 249-297/301.0
CLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMAMSQ
 |.|   |  |||||..||.|.    ... || |   | ...  ... .
glEQckaegVVdvfqvtkavrrskpgaVtTLeqytsiydvidmylqlns

subfamily_Urchin-PTP-5_pd Subfamily Urchin-PTP-5 2-54 5.2e-09 30.6 In-house 240-291 (297) alignment
Range on Protein: 2-54
Range on HMM: 240-291/297.0
CLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMaMSQENTL
.. . . |..||.|..|| ||..  ...|  |.||. | ...  . .|..  .
vvaeakrekevdifglvkklrqerpylvqtkeqykfvyvavleal.lsedtri

subfamily_Urchin-PTP-2_pd Subfamily Urchin-PTP-2 2-45 8.5e-09 29.2 In-house 394-437 (440) alignment
Range on Protein: 2-45
Range on HMM: 394-437/440.0
CLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHL
||.||. . |.|||| .. ||    ... .| || |||..| | 
cleqlnndgaidvfqnlrllrlsrpnfvptltdyllcykllthh

subfamily_Urchin-PTP-1_pd Subfamily Urchin-PTP-1 2-61 1.2e-08 29.2 In-house 233-290 (315) alignment
Range on Protein: 2-61
Range on HMM: 233-290/315.0
CLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMamSQENTLQSTQEFD
...|.. ...||||..|| || .  ...|. |.| . | ..   .     |||     | 
vvaqikrtrsvdvfnfvknlrakrpylvqteeeyafiydavledl..lwrntlilvihft

subfamily_Urchin-PTPRB-like_pd Subfamily Urchin-PTPRB-like 2-48 1.6e-08 29.0 In-house 235-281 (288) alignment
Range on Protein: 2-48
Range on HMM: 235-281/288.0
CLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMAM
 .|..| || .||. .|. ||.  ....| |. |  .|..| .|.  
lidaveeedyiDvagtvaklRkqRallvqtlkqYefiyevllsliee

subfamily_Urchin-PTP-4_pd Subfamily Urchin-PTP-4 2-44 6e-08 26.5 In-house 341-383 (392) alignment
Range on Protein: 2-44
Range on HMM: 341-383/392.0
CLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNH
|. |.   |.||.|| || || | .|..|. |.| . | . . 
ciaqiaegdsvdifqtvkilradrmqfvqteeeyafvydvire

subfamily_PTPN5_RR_pd Subfamily PTPN5_RR 2-45 5.3e-07 24.0 In-house 224-267 (274) alignment
Range on Protein: 2-45
Range on HMM: 224-267/274.0
CLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHL
.. ||. |  |||..||  || |   |.|. | |.| .|.| . 
avrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralcly

subfamily_Sponge-PTP11_pd Subfamily Sponge-PTP11 2-44 8.6e-07 23.1 In-house 239-281 (290) alignment
Range on Protein: 2-44
Range on HMM: 239-281/290.0
CLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNH
 ... . |  .||||..| .|    ...|. . |.. ..|. .
tinkcktegvidvfqvlksqRiqkpgsvqtvqqyqgifqivlt

subfamily_Choan-PTP-2_pd Subfamily Choan-PTP-2 2-46 4.6e-06 20.8 In-house 220-264 (270) alignment
Range on Protein: 2-46
Range on HMM: 220-264/270.0
CLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLM
..  || .  ||| .|...||.|  ...|  | |.. |. . . .
avrlLeetkkvdvlaiieelRkdRmalvqhpeqyeflykavveya

subfamily_Sponge-PTP6_pd Subfamily Sponge-PTP6 2-69 8.7e-06 19.4 In-house 235-300 (439) alignment
Range on Protein: 2-69
Range on HMM: 235-300/439.0
CLDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMamSQENTLQSTQEFDMEKDDGLS
.|.|| .|. ||.  ||| ||..  ||.|.| .| . |  .   .     ..  . .||  | . |.|
aleqlklenkvdikgivkvlrkqrkqmvqalcqyvfiynavledi..vyGdiavtidefkkefnagfs

subfamily_PTPRA_pd Subfamily PTPRA 3-46 6.1e-10 33.5 In-house 252-295 (330) alignment
Range on Protein: 3-46
Range on HMM: 252-295/330.0
LDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLM
|.... |  ||||..|| ||    ||.|..| |...|..| .  
lervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvlleyy

subfamily_Anemone-PTP-2_pd Subfamily Anemone-PTP-2 3-47 6.8e-10 33.7 In-house 247-291 (298) alignment
Range on Protein: 3-47
Range on HMM: 247-291/298.0
LDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMA
|.... |  |||||.||.||..  ...|. |.|. .| .  . ..
lervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavleald

subfamily_Ptp69D_pd Subfamily Ptp69D 3-50 7e-10 33.5 In-house 243-290 (307) alignment
Range on Protein: 3-50
Range on HMM: 243-290/307.0
LDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMAMSQ
|.||. || ||.|..|| ||..   ..|||| |. .|| |   . ...
lqqlkaedkvdifetvkdLrsqRnllvqsleqYvflyralldyssygd

subfamily_Nvec-PTP-2_pd Subfamily Nvec-PTP-2 3-50 2.3e-09 31.8 In-house 199-246 (250) alignment
Range on Protein: 3-50
Range on HMM: 199-246/250.0
LDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMAMSQ
|..|. |  ||||...|.||.|  ....||| |  .|.|. . .  ..
lerlkkekvvdvfkvikvlrkdrphavesleqyvfvyeiilkaldsve

subfamily_Anemone-PTP-6_pd Subfamily Anemone-PTP-6 3-52 4.5e-09 30.8 In-house 237-286 (318) alignment
Range on Protein: 3-52
Range on HMM: 237-286/318.0
LDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMAMSQEN
|.... |  |||||.|| ||.    |.|  . |...| .|   .|  . .
lerikaealvDvfqtvkqlreqrnlmvqtedqyefiydvllealasgdte

subfamily_Urchin-PTP-3_pd Subfamily Urchin-PTP-3 3-50 4.8e-08 27.5 In-house 245-292 (325) alignment
Range on Protein: 3-50
Range on HMM: 245-292/325.0
LDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMAMSQ
|...  |  ||.|. || ||.|  .|... . | |.|  |   .  ..
lakvieesrvdifgfvkklrkdrpsmvetvdqyiliyealveaymsgn

subfamily_PTPRK_pd Subfamily PTPRK 3-42 6.4e-08 26.8 In-house 234-273 (314) alignment
Range on Protein: 3-42
Range on HMM: 234-273/314.0
LDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRIL
|| .| |. ||||..||.||     |..  | ||..| ..
ldmieregvvdvfnavktlrsrkvnmveteeqykfiydvi

subfamily_Urchin-PTP-6_pd Subfamily Urchin-PTP-6 3-45 2.8e-07 24.0 In-house 233-275 (515) alignment
Range on Protein: 3-45
Range on HMM: 233-275/515.0
LDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHL
. . .  ..||||..|. .| .  ...|  |.| . | ..   
vahakttrmvdvfnfvtnirqkrpylvqtqeqyafiygavled

subfamily_Urchin-PTP-8_pd Subfamily Urchin-PTP-8 3-49 5.1e-07 24.5 In-house 212-260 (284) alignment
Range on Protein: 3-49
Range on HMM: 212-260/284.0
LDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILN--HLMAMS
||... |. |||...|. || .  ...|.| .||..|  |   ||.. |
ldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleehlfghs

subfamily_PTPRG_pd Subfamily PTPRG 3-58 5.7e-07 23.1 In-house 244-298 (563) alignment
Range on Protein: 3-58
Range on HMM: 244-298/563.0
LDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMAmSQENTLQSTQ
| |.. |.||.||...| .|     ..|. |.|   . .|  ..| |.|. |...|
lkqiqqenavnvfgflkhiraqRnflvqteEqYiflhdalleaia.sketellaeq

subfamily_Urchin-PTPRA_pd Subfamily Urchin-PTPRA 3-49 6.1e-07 24.0 In-house 248-296 (319) alignment
Range on Protein: 3-49
Range on HMM: 248-296/319.0
LDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRIL-N-HLMAMS
||... |. |||...|. || .  ...|.| .||..|  | . ||.. |
ldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleehlfghs

subfamily_Sponge-PTP5_pd Subfamily Sponge-PTP5 3-42 2e-06 21.9 In-house 223-262 (283) alignment
Range on Protein: 3-42
Range on HMM: 223-262/283.0
LDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRIL
....  |  ||||..|| .| .   ..|.|. ||| . . 
vkdaltesvvdvfavvkimreqrmmavqtldqyklvhelv

subfamily_PTPRB_pd Subfamily PTPRB 3-51 3.5e-06 21.3 In-house 242-290 (293) alignment
Range on Protein: 3-51
Range on HMM: 242-290/293.0
LDQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMAMSQE
|...| || ||.| || .||.. ....|. ..|   .. . .|.  ..|
lqaieeedyvdifgivaelReeRnllvqtekqYifihqcvldllrkkee

subfamily_PTPN12_pd Subfamily PTPN12 4-50 1.6e-06 22.2 In-house 235-281 (290) alignment
Range on Protein: 4-50
Range on HMM: 235-281/290.0
DQLEVEDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMAMSQ
 .  ... .|||..|  ||..   ..|. | |.| |. . .|.  . 
kaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelvqkel

AAA_PrkA PrkA AAA domain 9-68 4.8e-06 11.7 Pfam-A 217-276 (358) alignment
Range on Protein: 9-68
Range on HMM: 217-276/358.0
EDAVDVFQIVKALRHDNFQMIQSLEDYKLCYRILNHLMAMSQENTLQSTQEFDMEKDDGL
|.  |...   || . |  ... .| .|   ..| .|... ||....||... . . ||.
endpdaysysGalnranrGllefvemfkadikvlhplltatqegnyksteklslipfdgi