Gene SpurPTP-sf1-18 in Strongylocentrotus purpuratus

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family PTP
Subfamily SpurPTP-sf1
Protein sequence
ID Type Fasta BLAST phosphatome Note
SpurP095_AA protein Get Run
SpurP095_AA_0-68 phosphatase_domain Get Run
SpurP095_AA_66-111 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_Urchin-PTP-6_pd Subfamily Urchin-PTP-6 1-70 1.7e-42 140.2 In-house 99-168 (515) alignment 
Range on Protein: 1-70
Range on HMM: 99-168/515.0
MDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPGDSVKFGNIRVELVSLEACTGGIKRTMTMIEG
.|||||.|.||||||||||||||||||||||||||.|||||||||.|.|||||||||||||||..|.. |
vddfWrlvlqenvttiamvtklkegdkikcgkyWPdkpgdsvkfGsikvelvsleactggikrkltvlkg
subfamily_Urchin-PTP-1_pd Subfamily Urchin-PTP-1 1-68 1.8e-32 107.4 In-house 100-167 (315) alignment 
Range on Protein: 1-68
Range on HMM: 100-167/315.0
MDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPGDSVKFGNIRVELVSLEACTGGIKRTMTMI
.|||||||.||.||||.||||..||||||| .|||.. .|||.||.|.|||.||||.|.|..| ... 
vddfwrmvlqekvttivmvtkkqegdkikcrqywPdrkadsvefGsikvellsleadtdgvarklvtr
subfamily_Urchin-PTP-5_pd Subfamily Urchin-PTP-5 1-68 5.2e-23 76.6 In-house 105-169 (297) alignment 
Range on Protein: 1-68
Range on HMM: 105-169/297.0
MDDFWRMVWQENVTTIAMVTKLKEGDKiKCGKYWPNKPgdSVKFGNIRVELVSLEACTGGIKRTMTMI
..|||.||..|.|.||.|.....|.|| || .||..|   ...||.. |.| |.. ..|.|||.... 
vadfWamvldeqvstivmlnddnerdk.kcaryWsdkg..vttfGdvsvvllsvsereGfikrelevt
0046845 (Phosphotyrosine protein) phosphatases II 1-67 6.8e-22 73.6 In-house 90-155 (284) alignment 
Range on Protein: 1-67
Range on HMM: 90-155/284.0
MDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKpGDSVKFGNIRVELVSLEACTGGIKRTMTM
..|||||||..||..| |.|.| | ...|| .|||.. |.....|...|.|.| | . . ..||...
vedFwrmvweqnvrvIVmltelvengrekcaqYwple.gevltygdftvtllseevkddytvrtlel
0050432 (Phosphotyrosine protein) phosphatases II 1-67 8.2e-22 73.3 In-house 121-188 (308) alignment 
Range on Protein: 1-67
Range on HMM: 121-188/308.0
MDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPG-DSVKFGNIRVELVSLEACTGGIKRTMTM
..|||||||..||..| |.||| | ...|| .|||...| .|...|...|.|.| | . . ..||...
vedFwrmvweqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseevlddytvrtlel
subfamily_PTPRD_pd Subfamily PTPRD 1-67 1.5e-21 71.6 In-house 104-168 (564) alignment 
Range on Protein: 1-67
Range on HMM: 104-168/564.0
MDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKpGdSVKFGNIRVELVSLEACTGGIKRTMTM
..|||||||..|..|| |.|||.| .| || ||||.| | . ..|.. |.|.. |  .  . ||...
iedFWRmvweqnsstiVmltkleEkgkvkchkYWPek.g.tetygeltVtleeeeeladyeirtfkl
0051299 (Phosphotyrosine protein) phosphatases II 1-68 2.3e-21 71.9 In-house 105-170 (288) alignment 
Range on Protein: 1-68
Range on HMM: 105-170/288.0
MDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNkpGDSVKFGNIRVELVSLEACTGGIKRTMTMI
..|||||||..||..| |.||| | ...|| .|||.  |.|...|.|.|.|.| | . . ..||... 
vedFWrmvweqnvrvIvmltklvelgrekcaqYwpl..ggsltygditvtllseevlddytvrtlevt
DSPc_SM00195 1-66 8.2e-20 66.6 In-house 82-148 (263) alignment 
Range on Protein: 1-66
Range on HMM: 82-148/263.0
MDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPGDSVKFGNIRVELVSLEACT-GGIKRTMT
..|||||||.|.|..|.|.|. .| .|.|| .|||.. |.. .||.|.|.||. | .    |.||..
vedFWrmvweekvkiivmlteeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtle
PTPc_SM00194 1-66 8.2e-20 66.6 In-house 82-148 (263) alignment 
Range on Protein: 1-66
Range on HMM: 82-148/263.0
MDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPGDSVKFGNIRVELVSLEACT-GGIKRTMT
..|||||||.|.|..|.|.|. .| .|.|| .|||.. |.. .||.|.|.||. | .    |.||..
vedFWrmvweekvkiivmlteeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtle
Y_phosphatase Protein-tyrosine phosphatase 1-64 1.7e-19 65.6 Pfam-A 55-120 (235) alignment 
Range on Protein: 1-64
Range on HMM: 55-120/235.0
MDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPGDSVKFGNIRVELV-SLE-ACTGGIKRT
..|||||||||.|..|.|.|.|.| .. || .|||.. ..|...|.|.|||. . . .... . |.
iedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesltygdikvelkekekedekeytlrk
Y_phosphatase Protein-tyrosine phosphatase 1-64 1.7e-19 65.6 In-house 55-120 (235) alignment 
Range on Protein: 1-64
Range on HMM: 55-120/235.0
MDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPGDSVKFGNIRVELV-SLE-ACTGGIKRT
..|||||||||.|..|.|.|.|.| .. || .|||.. ..|...|.|.|||. . . .... . |.
iedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesltygdikvelkekekedekeytlrk
subfamily_Urchin-PTPRB-like_pd Subfamily Urchin-PTPRB-like 1-66 9e-19 62.6 In-house 103-167 (288) alignment 
Range on Protein: 1-66
Range on HMM: 103-167/288.0
MDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKpGDSVKFGNIRVELVSLEACTGGIKRTMT
..|||..|......||.|.|.| ||.| ||..|||.. .. ...|.. |.||. .  .  ..|.. 
vndfWelvyenktstivmltelveggktkCeeYWPda.dkpknyGsvtvtlveskeledfvlrkll
subfamily_PTPRB_pd Subfamily PTPRB 1-67 1.1e-18 62.3 In-house 107-172 (293) alignment 
Range on Protein: 1-67
Range on HMM: 107-172/293.0
MDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPgDSVKFGNIRVELVSLEACTGGIKRTMTM
.||||||||......| |.|.| |. |.|| .|||..  ..| .|.|.|.||. |  .  . |....
vddfWrmvwekkssiivmltqlvekgkvkCeeYWPade.epvlyGdikvtlvaeeeledwvirelki
subfamily_Choan-PTP-1_pd Subfamily Choan-PTP-1 1-67 6.5e-18 59.8 In-house 97-162 (281) alignment 
Range on Protein: 1-67
Range on HMM: 97-162/281.0
MDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPnKPGDSVKFGNIRVELVSLEACTGGIKRTMTM
...||.|||...|..|.|||.  |..|.|| .|||  .  ..|.|...|. .. |. .  |.|....
lvafWqmvweqkvsaivmvtreieagklkChrYWP.ddnselkygdvtvkstaeeekatyierkfkl
subfamily_Anemone-PTP-2_pd Subfamily Anemone-PTP-2 1-66 4.1e-17 57.4 In-house 112-175 (298) alignment 
Range on Protein: 1-66
Range on HMM: 112-175/298.0
MDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKpgDSVKFGNIRVELVSLEACTGGIKRTMT
. ||||||..|...|| |.|.|.| ||.|. ||||..   . ..|.|.|.| | |  .  |.|...
vedFWrmvteedigtiVmltnleeldktkyhkywPde..gketygeitvsllskeefadlivrklk
subfamily_PTPRG_pd Subfamily PTPRG 1-66 7.6e-17 55.7 In-house 104-167 (563) alignment 
Range on Protein: 1-66
Range on HMM: 104-167/563.0
MDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNkpGDSVKFGNIRVELVSLEACTGGIKRTMT
.||||||.|..||..| |.|.|.|  . ||  |||.   .|...|...| |.. |  .   .||..
fddFWrmiWeqnvaiivmitnlvergrrkcdvYWPk..desetygalqvtlieeevlalytvrtlv
subfamily_Anemone-PTP-6_pd Subfamily Anemone-PTP-6 1-65 8.7e-17 56.1 In-house 102-164 (318) alignment 
Range on Protein: 1-65
Range on HMM: 102-164/318.0
MDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKpgDSVKFGNIRVELVSLEACTGGIKRTM
..|||||||. | ..| |.|...|  |.|. .|||.|  .| ..|...||| .   ..  . |..
ieDfWrmvWeqnsavivmltqeeergkakvhryWPsk..gsrsygklvvelkeevelsdyvlref
subfamily_PTPN12_pd Subfamily PTPN12 1-65 3.5e-15 50.7 In-house 96-161 (290) alignment 
Range on Protein: 1-65
Range on HMM: 96-161/290.0
MDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPGDSVKFGNIRVELVSLEACT-GGIKRTM
.||||||.|. ||. . |. .. | .|.|| .|||.. .....||...|.| . .|.. . . ||.
lddfWrmiweknveivvmaCrevelgkkkCerYWpeegeeelefgefevtleeekavdddflirtL
subfamily_Anemone-PTP-5_pd Subfamily Anemone-PTP-5 1-67 2.3e-14 48.2 In-house 104-168 (319) alignment 
Range on Protein: 1-67
Range on HMM: 104-168/319.0
MDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKpgDSVKFGNIRVELVSLEACTGGIKRTMTM
..|||||||.|.. .. |.|||.|  |.|. ||||..  . ...|.. |.| . |   . |.| ...
iedfWrmvWeeessivvmltklveklkvklkkywpee..nfeeyGrlivtleeeeeledyiirklkl
subfamily_Urchin-PTP-4_pd Subfamily Urchin-PTP-4 1-37 2e-13 44.5 In-house 101-145 (392) alignment 
Range on Protein: 1-37
Range on HMM: 101-145/392.0
MDDFWRMVWQENVTTIAMVTKLKEGDKI----KCGKY----WPNK
.|||||||.||||||||||||||||||      . ..    ||.|
lddfwrmvfqenvttiamvtklkegdkgddartvaqfhftewPdk
subfamily_PTPN14_pd Subfamily PTPN14 1-50 2.6e-13 44.6 In-house 106-157 (300) alignment 
Range on Protein: 1-50
Range on HMM: 106-157/300.0
MDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNK--PGDSVKFGNIRVE
. |||.|||...|. |.|.|. .|. | |. ||.|..    ..|.||. .| 
vqdfWqmvWeqgvqlivmlteeeedgkeksfkyfPkleskkktvefgkfkvt
subfamily_CG7180_pd Subfamily CG7180 1-65 1.3e-12 42.0 In-house 98-159 (296) alignment 
Range on Protein: 1-65
Range on HMM: 98-159/296.0
MDDFWRMVWQENVTTIAMVTKLKEGDKiKCGKYWPNKPgdSVKFGNIRVELVSLEACTGGIKRTM
.|.|||.|..|.. .. ..||  .  | .. .|||||     ..|.| ||.|. .  .   .||.
vdefWrlvydeeisavvvLtktfdfak.mypsywpnks..keqygeifveiveekqyanlkirtf
subfamily_Urchin-PTPRA_pd Subfamily Urchin-PTPRA 1-53 8.5e-12 40.0 In-house 117-163 (319) alignment 
Range on Protein: 1-53
Range on HMM: 117-163/319.0
MDDFWRMVWQENVTTIAMVTklkegdKIKCGKYWPNKPGDSVKFGNIRVELVS
..|||||.|. |..|| ..|      | || .|||.|     . ....|..| 
ladfWrmiweyncstivllt......kdkcsqywplkivikeerfkvkvdsve
subfamily_Urchin-PTP-8_pd Subfamily Urchin-PTP-8 1-53 1.1e-11 39.8 In-house 81-127 (284) alignment 
Range on Protein: 1-53
Range on HMM: 81-127/284.0
MDDFWRMVWQENVTTIAMVTklkegdKIKCGKYWPNKPGDSVKFGNIRVELVS
..|||||.|. |..|| ..|      | || .|||.|     . ....|..|.
ladfWrmiweyncstivllt......kdkcsqywplkivikeerfkvkvdsve
subfamily_Cele-PTP-10_pd Subfamily Cele-PTP-10 1-53 1.3e-09 32.1 In-house 109-162 (305) alignment 
Range on Protein: 1-53
Range on HMM: 109-162/305.0
MDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPGDSVKF-GNIRVELVS
.|.|| || |..|  | |. |  |  |.|| .|||   |. ... . | || ||
idefwwmviqnkveqivmlcktvelgklkcaqywpaaqgeklelksgivvenvs
0049260 (Phosphotyrosine protein) phosphatases II 1-68 1e-08 30.5 In-house 22-107 (152) alignment 
Range on Protein: 1-68
Range on HMM: 22-107/152.0
MDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYW-------PNKPGDSVKFGNIRVELVSLE-----------ACTGGIKRTMTMI
..|||||... ..||| |.|.| | .|.|| .|.       |  .  .  .  . . |.  .            |..|. || |..
ladfwrmlkelgittivmltellelgklkceqyiqylhlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlv
subfamily_Fungi-PTP1_pd Subfamily Fungi-PTP1 1-62 2e-08 28.3 In-house 117-173 (350) alignment 
Range on Protein: 1-62
Range on HMM: 117-173/350.0
MDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKpgdsvKFGNIRVELVSLEACTGGIK
.|||.... . .|. | ..|.. | .  || .||..      .. .| | | |    ..||.
vddfykvillnkvkvilsltsdvelnlekcyrYWqeg.....sydditvklaskwenimgin
subfamily_Cele-PTP-9_pd Subfamily Cele-PTP-9 1-67 3.4e-08 27.9 In-house 41-105 (255) alignment 
Range on Protein: 1-67
Range on HMM: 41-105/255.0
MDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPGDSVKFGNIRVELVSleACTGGIKRTMTM
.| |.... | . ....|.. ..| .. || .|.| .  .  |. .. |      . .  . ||...
vdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdeklkladvnvtttk..ssadvvlrtlei
subfamily_hpo-7_pd Subfamily hpo-7 1-67 1.6e-07 25.5 In-house 47-111 (263) alignment 
Range on Protein: 1-67
Range on HMM: 47-111/263.0
MDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPGDSVKFGNIRVELVSLEActGGIKRTMTM
.| |.... | . ....|..  .| .. || .|.| .  .  |. |. |           ...|  .
idkfyqtivqtktevvvmLcDfneegvekcssyfPlekdekqklanvnvcttkvqs..dvllktlel
subfamily_Anemone-PTP-3_pd Subfamily Anemone-PTP-3 1-53 1.8e-06 22.3 In-house 18-70 (199) alignment 
Range on Protein: 1-53
Range on HMM: 18-70/199.0
MDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPGDSVKFGNIRVELVS
| |||.|||.     | ||   .   .     |||     . |.|.. |   .
madfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttkt
subfamily_Nvec-PTP-3_pd Subfamily Nvec-PTP-3 1-53 2.4e-06 21.9 In-house 17-69 (198) alignment 
Range on Protein: 1-53
Range on HMM: 17-69/198.0
MDDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPGDSVKFGNIRVELVS
. |||.|||.     | ||   .   .     |||     . |.|.. |   .
ladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttkt
0036941 (Phosphotyrosine protein) phosphatases II 2-67 2.3e-21 71.8 In-house 92-159 (297) alignment 
Range on Protein: 2-67
Range on HMM: 92-159/297.0
DDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPGDSVKFGNIRVELVSLEA--CTGGIKRTMTM
.|||||||..|||.| |.|.| | ...|| .|||.. |.|...|...|.|.| |   ... . ||...
edFWrmvweqnvtvIvmltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlev
0047943 (Phosphotyrosine protein) phosphatases II 2-67 1.1e-20 69.7 In-house 91-157 (273) alignment 
Range on Protein: 2-67
Range on HMM: 91-157/273.0
DDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPGD-SVKFGNIRVELVSLEACTGGIKRTMTM
.|||||||..||..| |.|.| | ...|| .|||.. |. |...|...|.|.| | . . ..||...
edfwrmvweqnvrviVmLtelvelgrekcaqYwpleggelsltygkftvtllseetkddytvrtlel
0040438 (Phosphotyrosine protein) phosphatases II 2-67 5e-20 67.4 In-house 100-163 (317) alignment 
Range on Protein: 2-67
Range on HMM: 100-163/317.0
DDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNkpGDSVKFGNIRVELVSLEACTGGIKRTMTM
.|||||||...||.| |.|.|.| ...|| .|||.  |.....|...|.|.| | . | . ||...
edFwrmvweqgvtvivmLteleelgrekcaqYwpl..getltygdftvtllseeelagitlrtlev
subfamily_Ptp69D_pd Subfamily Ptp69D 2-67 4.1e-19 63.8 In-house 105-168 (307) alignment 
Range on Protein: 2-67
Range on HMM: 105-168/307.0
DDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKpgDSVKFGNIRVELVSLEACTGGIKRTMTM
.|||||... .||.| |...|.| .. || ||||.   | |..|.| |.||| | ..  |.|.. .
gDfWRmiaeqevtlivmlsnlteknrkkcakYWpie..devqygdilvklvseekhsdyiiReldv
0043336 (Phosphotyrosine protein) phosphatases II 2-68 4.2e-19 64.5 In-house 102-165 (278) alignment 
Range on Protein: 2-68
Range on HMM: 102-165/278.0
DDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPnkpGDSVKFGNIRVELVSLEACTGGIKRTMTMI
.|||||||...|||| |.|.|.| ...|| .|||   |.|...|...|.|.. | . . . ||... 
edFwrmvwelgvttivmLtelvelgrvkcaqYwp...ggsltygdftvtllkeehlddytvrtlevt
subfamily_PTPN9_pd Subfamily PTPN9 2-66 5.4e-19 63.3 In-house 99-163 (297) alignment 
Range on Protein: 2-66
Range on HMM: 99-163/297.0
DDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPGDSVKFGNIRVELVSLEACTGGIKRTMT
.|||||||...| .| |.|.. |  ..|||.|||.. ..| .||...|. |. |      .|...
sdfWrmvWeqevlvivmttrvvergrlkcgqyWpleeessaefgdlsvsnveveeeedykvrvle
0045450 (Phosphotyrosine protein) phosphatases II 2-67 5.7e-19 64.4 In-house 121-185 (307) alignment 
Range on Protein: 2-67
Range on HMM: 121-185/307.0
DDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKpGDSVKFGNIRVELVSLEACTGGIKRTMTM
.|||||.|...||.| |.|.|.| ...|| .|||.. |... .||..|.|.| | . | . ||...
edFwrmlweqgvtvivmltelvelgrekcaqywPde.geeltygnftvtllseehldgytvrtlev
subfamily_PTPRK_pd Subfamily PTPRK 2-68 1.3e-18 61.9 In-house 100-163 (314) alignment 
Range on Protein: 2-68
Range on HMM: 100-163/314.0
DDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNkpgDSVKFGNIRVELVSLEACTGGIKRTMTMI
 ||||.|..|| ..| |.|.|.|  ..|| ||||.   |. ..|.|.||||. |. .  ..|.... 
kdfWrlvydencasivmltelvevgrvkClkyWPe...dtevygdikvelvetellaelvvrifrve
0045098 (Phosphotyrosine protein) phosphatases II 2-68 2e-18 62.3 In-house 78-142 (278) alignment 
Range on Protein: 2-68
Range on HMM: 78-142/278.0
DDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNkpGDSVKFGNIRVELVSLEACTGGIKRTMTMI
.|||||.|....|.| |.|.|.|....|| .|||.  |.|. .|...|.|.| | .   ..||....
adfwrmlwelgitvivmltelvelgrekcaqywpe..ggsltygdftvtllseevlddytlrtllvt
subfamily_Sponge-PTP8_pd Subfamily Sponge-PTP8 2-67 2.2e-18 61.4 In-house 103-168 (305) alignment 
Range on Protein: 2-67
Range on HMM: 103-168/305.0
DDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPGDSVKFGNIRVELVSLEACTGGIKRTMTM
.||||....| |.|| |.|||.||.| || .|||.. .....||.. ||| | .. .. |.| ...
adfWrliveekvstivmltklveggkdkCrqYWpesktekkefgefsvelksektasdyieRklki
0039614 (Phosphotyrosine protein) phosphatases II 2-67 2.6e-18 62.0 In-house 115-176 (297) alignment 
Range on Protein: 2-67
Range on HMM: 115-176/297.0
DDFWRMVWQENVTTIAMVTKLKEGDKiKCGKYWPNKPGdsvKFGNIRVELVSLEACTGGIKRTMTM
.|||||||...||.| |.|||.| .. || .|||.. |   ..|...|.|.. | . | . ||...
edFwrmvweqgvtvivmLtklvelgr.kcaqywpeegg...tygdftvtllkvehldgytvrtlev
0040439 (Phosphotyrosine protein) phosphatases II 2-67 5.2e-18 61.0 In-house 68-131 (249) alignment 
Range on Protein: 2-67
Range on HMM: 68-131/249.0
DDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNkpGDSVKFGNIRVELVSLEACTGGIKRTMTM
.|||||.|....|.| |.|.|.| ...|| .|||.  |.|...|...|.|.| | . . . ||...
edfwrmlwelgitvivmLtslvelgrekcaqywpl..ggsleygdftvtllsvevkddytvrtlel
subfamily_PTPN13_pd Subfamily PTPN13 2-69 6.1e-18 60.1 In-house 91-159 (273) alignment 
Range on Protein: 2-69
Range on HMM: 91-159/273.0
DDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPGDSVKFGN-IRVELVSLEACTGGIKRTMTMIE
.|||.|||. ... |||||. ||..|.|| .|||.. ....|  | ..|||. ..   |   |......
kdfwqmvweqkaeviamvtlekekgkvkchrywPesknkklkvsnrlevellkvqkldgfvvralavkd
0042113 (Phosphotyrosine protein) phosphatases II 2-67 1.2e-17 59.6 In-house 66-129 (245) alignment 
Range on Protein: 2-67
Range on HMM: 66-129/245.0
DDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNkpGDSVKFGNIRVELVSLEACTGGIKRTMTM
.|||||.|....||| |.|.. | ...|| .|||.  |.|...|...|.|.| | . . . ||...
edfwrmlwelgittivmLteeeelgrvkcaqywpl..gesltygdftvtllseehlddytvrtlev
subfamily_PTPRA_pd Subfamily PTPRA 2-57 4.8e-17 56.8 In-house 115-168 (330) alignment 
Range on Protein: 2-57
Range on HMM: 115-168/330.0
DDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKpgDSVKFGNIRVELVSLEAC
.|||||.|. . .|| |.|.||| .. || .|||..   .| .||||||.   . .
edfwrmiweqksativmltelkerkeekcaqywPde..GlvtyGnirvevedetvl
subfamily_Sponge-PTP11_pd Subfamily Sponge-PTP11 2-67 5.6e-17 56.5 In-house 105-168 (290) alignment 
Range on Protein: 2-67
Range on HMM: 105-168/290.0
DDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKpgDSVKFGNIRVELVSLEACTGGIKRTMTM
 |||...|||.|| | |.|. .| .| || .|||..  |. ..|.....|.. |.... |.|.. .
vdFWkliwqekvtiivmltniieegkvkCqqYWpds..dtkaygefsikllneetlneyierklev
subfamily_PTPN6_pd Subfamily PTPN6 2-67 6.5e-17 56.5 In-house 112-176 (306) alignment 
Range on Protein: 2-67
Range on HMM: 112-176/306.0
DDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPGDSVkFGNIRVELVSLEACTGGIKRTMTM
 |||||||||| . | |.||  |  | || .|||..  ..  .|.|.|. || .. .  | |....
sdFWrmvwqensrvivmttkevErgkekCarYWPdeeekee.yGkisvtnvseksladYilRelsv
subfamily_PTPN23_pd Subfamily PTPN23 2-67 7.2e-17 56.1 In-house 97-162 (288) alignment 
Range on Protein: 2-67
Range on HMM: 97-162/288.0
DDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPGDSVKFGNIRVELVSLEACTGGIKRTMTM
 |||.||... . .| |... .| .| |. .|||.. |..||||...| | | .     ..|....
nDFWlmvyeqkssviVmllskeelgkpkvdrYwPedkgetvkfgdlsvtlksvretethvervlkl
subfamily_Choan-PTP-2_pd Subfamily Choan-PTP-2 2-66 8e-17 56.1 In-house 78-144 (270) alignment 
Range on Protein: 2-66
Range on HMM: 78-144/270.0
DDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPGD--SVKFGNIRVELVSLEACTGGIKRTMT
 .||||.|.|.||.|.|.|.|.|  . || .|||..|..  ....|.|.|  .| |  .| |.. ..
ksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkekvkledgkikvlalseekeegyiltrlr
subfamily_PTPN3_pd Subfamily PTPN3 2-68 1.1e-16 55.6 In-house 98-163 (280) alignment 
Range on Protein: 2-68
Range on HMM: 98-163/280.0
DDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNkPGDSVKFGNIRVELVSLEACTGGIKRTMTMI
 |||.|||......| |.| | |  ..|| .|||. ..|....|...|.. . .. .  . | ... 
tdfWqmvweqksslivmlttlverGrvkChqyWPe.tedeleygefsvkcekedetksyvlrelvlk
subfamily_Urchin-PTP-7_pd Subfamily Urchin-PTP-7 2-69 1.3e-16 55.4 In-house 106-170 (315) alignment 
Range on Protein: 2-69
Range on HMM: 106-170/315.0
DDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKpgdSVKFGNIRVELVSLEACTGGIKRTMTMIE
.||||.|..|....| |.|.| ||.| |. ||||.|    | .|.| | ..| |  |    ||.... 
kdfwrlvfeedigkivmltnlvegekrkaekywpdk...kviyGkitvtrkseevnteytvrtlsvvf
0037934 (Phosphotyrosine protein) phosphatases II 2-67 1.7e-16 56.0 In-house 58-123 (243) alignment 
Range on Protein: 2-67
Range on HMM: 58-123/243.0
DD----FWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPnkpgDSVKFGNIRVELVSLEACTGGIKRTMTM
.|    ||||.|....|.| |.|.|.| ...|| .|||    ..| .|...|.|.| | . . . ||...
eddlasfwrmlwelgitvivmltelvElgrekcaqywp....gevtygdftvtllseehlddytvrtlll
subfamily_Choan-PTP-4_pd Subfamily Choan-PTP-4 2-53 5e-16 53.4 In-house 90-141 (297) alignment 
Range on Protein: 2-53
Range on HMM: 90-141/297.0
DDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPGDSVKFGNIRVELVS
||||..|....| .|.||.||.|. . ||  |||.  ..  | |.. || .|
ddfwtlvaeqdvrvivmvaklqedGrdkcapywpsvvqerlkagdvvvefls
subfamily_Nvec-PTP-2_pd Subfamily Nvec-PTP-2 2-66 6e-16 53.4 In-house 66-127 (250) alignment 
Range on Protein: 2-66
Range on HMM: 66-127/250.0
DDFWRMVWQENVTTIAMVTKLKEGDKIkCGKYWPNKpgDSVKFGNIRVELVSLEACTGGIKRTMT
 ||||||..|...|| |.|.||| .|  . .||| .   . |.|...|.| | |  .  .||.. 
edfWrmvleeksgtivmLtnLkesekt.yhqywPve..kaekyGdvtvsllskeefadytkrklk
subfamily_Urchin-PTP-3_pd Subfamily Urchin-PTP-3 2-66 7.1e-16 53.2 In-house 105-168 (325) alignment 
Range on Protein: 2-66
Range on HMM: 105-168/325.0
DDFWRMV--WQenvTTIAMVTKLKEGDKIKCGKYWPNKPGDSVKFGNIRVELVSLEACTGGIKRTMT
.|.||.|  |.   ... .|.   ...| .| .|||.. |.|..|| ..|.|...|  .  ..| . 
ndlWrlvldWr...csvvvvlneldlgkdrcavywpkemgksktfGglevklrtieeisdyvhrvld
subfamily_PTPN5_RR_pd Subfamily PTPN5_RR 2-68 8.9e-16 52.8 In-house 87-155 (274) alignment 
Range on Protein: 2-68
Range on HMM: 87-155/274.0
DDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPGD--SVKFGNIRVELVSLEACTGGIKRTMTMI
.|||||..||.|. | |.||||| .. || .|.|.. .   | ..|.. .. ..   . .   |.... 
adfWrmiyqeevqvivmltklkeaneqkCavyfPdaedyeiserygdveikvekiverndysvrklvlk
subfamily_Sponge-PTP9_pd Subfamily Sponge-PTP9 2-59 2.3e-15 51.1 In-house 99-156 (301) alignment 
Range on Protein: 2-59
Range on HMM: 99-156/301.0
DDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPGDSVKFGNIRVELVSLEACTG
 ||||..||| ...| |||.|||| | || .||||   .| .||.. |.||.  .   
vdfWrliwqekpvsivmvtnlkegtkskceqywpnseaeseefgpftvtlvneqvyPd
subfamily_Anemone-PTP-1_pd Subfamily Anemone-PTP-1 2-67 1.1e-14 49.2 In-house 66-128 (239) alignment 
Range on Protein: 2-67
Range on HMM: 66-128/239.0
DDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKpgdSVKFGNIRVELVSLEACTGGIKRTMTM
 |||||.|||    | |.| | || | || .|||.    . |. |.|| |   |  .  | ||. |
gdfwrmmwqerrcvivmltglieghkkkchqywpds...tskycnlrvtlrktevfadyiirtfvm
subfamily_Anemone-PTP-4_pd Subfamily Anemone-PTP-4 2-66 1.1e-14 49.2 In-house 59-122 (237) alignment 
Range on Protein: 2-66
Range on HMM: 59-122/237.0
DDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKpGDSVKFGNIRVELVSLEACTGGIKRTMT
||||.|||||. . | |.| | ||...|| ||||.   .   .| . | |   |. .    |...
ddfwqmvwqekcsvivmltgliegnelkchkywpst.dqpaaygvltvslkkkeefsdytvrsll
subfamily_Nvec-PTP-1_pd Subfamily Nvec-PTP-1 2-67 1.1e-14 49.2 In-house 65-127 (239) alignment 
Range on Protein: 2-67
Range on HMM: 65-127/239.0
DDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKpgdSVKFGNIRVELVSLEACTGGIKRTMTM
 |||||.|||    | |.| | || | || .|||.    . |. |.|| |   |  .  | ||. |
gdfwrmmwqerrcvivmltglieghkkkchqywpds...tskycnlrvtlrktevfadyiirtfvm
subfamily_egg_pd Subfamily egg 2-55 1.4e-13 45.2 In-house 97-150 (307) alignment 
Range on Protein: 2-55
Range on HMM: 97-150/307.0
DDFWRMVWQENVTTIAMVTKLKEGDkiKCGKYWPNKPGDSVKF--GNIRVELVSLE
|||||||.||.|  | |.|  || .  .|  |||. . ||...  |..|.| . ..
ddfwrmvfqeevqyivmltsrkese..rceyywpkaesdslvtvpGslrienlkvd
subfamily_Cele-PTP-15_pd Subfamily Cele-PTP-15 2-69 1.5e-12 42.1 In-house 89-158 (285) alignment 
Range on Protein: 2-69
Range on HMM: 89-158/285.0
DDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPGDSVKFGNIRVELVS--LEACTGGIKRTMTMIE
 |||.|..||... . |.  | ||   ||  |.|.| |. ||||.  . |     || .| |  ..|.|.
sdfwhmiyqekiayvlmlctlfeggvekcalyypeklgevvkfgkyeitlteckeeaiagtilnaltvin
subfamily_PTPN1_pd Subfamily PTPN1 2-58 1.7e-12 41.7 In-house 85-144 (290) alignment 
Range on Protein: 2-58
Range on HMM: 85-144/290.0
DDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPG-DSVKFG--NIRVELVSLEACT
| ||.|||...  .. |. |. | ..||| .|||..   .....   ...|.|.| |   
dhfWqmvWeqkskavvmlnkvvekeqikcaqywPqgeeekellledtklkvkliseerks
subfamily_Choan-PTP-3_pd Subfamily Choan-PTP-3 2-53 1.1e-10 35.8 In-house 94-144 (287) alignment 
Range on Protein: 2-53
Range on HMM: 94-144/287.0
DDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKpGDSVKFGNIRVELVS
 ||||.|...........|.  |  . || ||||..    .. |   | |..
rdfwravletrsasvitmtreveearlkcykywPer.evPmrvGGysvvlld
0051429 (Phosphotyrosine protein) phosphatases II 2-68 3.9e-10 35.4 In-house 36-111 (272) alignment 
Range on Protein: 2-68
Range on HMM: 36-111/272.0
DDFWRMvWQENVTTIAMVTKLKEGDKIKCGKYWP----------NKPGDSVKFGNIRVELVSLEACTGGIKRTMTMI
.||||. ......|| ..... | .. || .|||          .    .. .|..|| |.| | ..  | |.....
adfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseellldyilrelllt
subfamily_PTPRN_pd Subfamily PTPRN 2-53 5.5e-10 33.4 In-house 114-163 (297) alignment 
Range on Protein: 2-53
Range on HMM: 114-163/297.0
DDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKpGDSVkFGNIRVELVS
 |||.|||.. |. | ..|.|.| .  .| .|||.. | .| ..   |.|||
adfwqmvweqGvvvivnltrleeegvkqckrywpde.Gsev.yhiyevhlvs
subfamily_Cele-PTP-1_pd Subfamily Cele-PTP-1 2-67 1.1e-09 32.9 In-house 81-150 (290) alignment 
Range on Protein: 2-67
Range on HMM: 81-150/290.0
DDFWRMVWQENVTTIAMVTKLKEGDKI----KCGKYWPNKPGDSVKFGNIRVELVSLEACTGGIKRTMTM
 .|| |. ||.|. . |. . .| ..      | || |.. |...||... |.  | |.  . ..|....
ekfwwmakqEkvkqvVmlcefeeksantslfaCakYvpesvgeelkfkgltvkCkskekeddvetRelvv
subfamily_ptpA1_pd Subfamily ptpA1 2-39 3.7e-09 30.8 In-house 103-140 (418) alignment 
Range on Protein: 2-39
Range on HMM: 103-140/418.0
DDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPG
 |||||||.. .  | |...  |  .||| .|||.. |
adfwrmvwenrcriivmlsresencrikcdrywpeqig
subfamily_Cele-PTP-19_pd Subfamily Cele-PTP-19 2-56 4.8e-09 30.4 In-house 104-158 (301) alignment 
Range on Protein: 2-56
Range on HMM: 104-158/301.0
DDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPGDSVKFGNIRVELVSLEA
.||| |. | .| .|.|...  |  . || .| | |...... |  ...... | 
edfwamlvqydvekivmlgqkvekleekceeylpvkisekldigrfkikiknkel
0046846 (Phosphotyrosine protein) phosphatases II 2-41 1.6e-08 30.0 In-house 37-76 (176) alignment 
Range on Protein: 2-41
Range on HMM: 37-76/176.0
DDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPGDS
 ||..|......|.. ..|...| ...||  |||   . .
adflemlkelgitavvnlteevelgrlkcpnywpeleklg
subfamily_Cele-PTP-7_pd Subfamily Cele-PTP-7 2-56 7.2e-08 26.2 In-house 105-159 (302) alignment 
Range on Protein: 2-56
Range on HMM: 105-159/302.0
DDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPGDSVKFGNIRVELVSLEA
. .| .. | ||. .. .....|... || .|. .| |. .|||.  |. ||.. 
ekhwalieqynvaivvqlcsfvedeekkcaeyysdkvggelkfgrytvktvsvkt
subfamily_Sponge-PTP6_pd Subfamily Sponge-PTP6 2-50 2.5e-07 24.5 In-house 105-146 (439) alignment 
Range on Protein: 2-50
Range on HMM: 105-146/439.0
DDFWRMVWQENVTTIAMVTKLKEGDKikcgkYWPNKpgDSVKFGNIRVE
|||||.|......|| |.|.| |  |     ||| .  . | .|.| | 
ddfwrlviekktvtivmltnlvesyk.....ywpsd..aevcygdiavr
subfamily_Cele-PTP-4_pd Subfamily Cele-PTP-4 2-50 5.5e-07 23.3 In-house 107-154 (302) alignment 
Range on Protein: 2-50
Range on HMM: 107-154/302.0
DDFWRMVWQENVTTIAMVTKLKEGDKiKCGKYWPNKPGDSVKFGNIRVE
..|||||.||..... .. . .| .|    ...|.| || ...|...| 
eeFWrmvfqekivsvvilvgeeelkk.tlselfpkksgdykeygkmfvN
0041856 (Phosphotyrosine protein) phosphatases II 2-42 7.2e-07 24.4 In-house 48-79 (182) alignment 
Range on Protein: 2-42
Range on HMM: 48-79/182.0
DDFWRMVWQENVTTIAMVTklkegdkikCGKYWPNKPGDSV
 ||.||......||| ..|         .  |||..  . .
adflrmlkelgittivnlt.........eelywpellerlg
0051082 (Phosphotyrosine protein) phosphatases II 2-67 7.7e-07 24.4 In-house 23-109 (151) alignment 
Range on Protein: 2-67
Range on HMM: 23-109/151.0
DDFWRMVWQENVTTIAMVTKLKEGDkiKCGKYWPNKPGDSVKFGNIRV-----------------------ELVSLEACTGGIKRTMTM
.||..........|| ......| .  .| .|.|.   . . .  .                         . . |  |..|. || |.
adflellkelgiktivnlrseeerg..ycpeylpelgievlhipildwpdpglplsfdavleflellldkkngpvlvHCsaGkgRTGtl
subfamily_Cele-PTP-8_pd Subfamily Cele-PTP-8 2-65 1.1e-06 22.9 In-house 96-156 (288) alignment 
Range on Protein: 2-65
Range on HMM: 96-156/288.0
DDFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPGDSVKFGNIrvelvsleaCT------GGIKRTM
. .|.|. ...|  | |...| |  | |  .|.| | |.....| .         ||       .|....
eelWkmllesdveyivmlcellekGkeksaeyfPsklGekarigrl.........ctvvkkkradidklv
subfamily_Sponge-PTP5_pd Subfamily Sponge-PTP5 3-53 4.7e-17 56.8 In-house 90-138 (283) alignment 
Range on Protein: 3-53
Range on HMM: 90-138/283.0
DFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKpgDSVKFGNIRVELVS
|||.||..|..|.| |.|||.|. .||| .|||..   |...|.  | |  
dfWkmvfdekitaivmltklqedlrikCsqyWPkr..GsedyGeftvtlrk
subfamily_Sponge-PTP10_pd Subfamily Sponge-PTP10 3-68 7.5e-17 56.2 In-house 101-164 (287) alignment 
Range on Protein: 3-68
Range on HMM: 101-164/287.0
DFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKpgDSVKFGNIRVELVSLEACTGGIKRTMTMI
.||......|||.| |....|| |. .| .|||..  .|| .|. ..||.. |  .| |.|.. ..
nfWkliddrnvtaivmlcqekendeevcyqyWpee..ksvvlGeyniellneevnagyierklevk
subfamily_Cele-PTP-20_pd Subfamily Cele-PTP-20 3-51 1.8e-12 41.5 In-house 109-157 (290) alignment 
Range on Protein: 3-51
Range on HMM: 109-157/290.0
DFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPGDSVKFGNIRVEL
|.|||| ||.|..| |. .| |  | || .|.|.| |. . ||.| |  
diwrmvlqekvaaivmlceliedGkakceqyypekeGevltfGeitvlc
subfamily_Cele-PTP-13_pd Subfamily Cele-PTP-13 3-50 3.7e-11 37.2 In-house 96-143 (281) alignment 
Range on Protein: 3-50
Range on HMM: 96-143/281.0
DFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPGDSVKFGNIRVE
|||||.|||| |.| |. .. | .. || .|.| .    ..| .. |.
dfwrmiwqenttaivmlcqfletnrekcaeyfprnahcclqfdklsvs
subfamily_Cele-PTP-6_pd Subfamily Cele-PTP-6 3-47 2.8e-10 34.7 In-house 97-141 (307) alignment 
Range on Protein: 3-47
Range on HMM: 97-141/307.0
DFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPGDSVKFGNI
.|| |. ||.| .. |. |. |  |||| .||| . |.   ||. 
sfwamaiqekvesvimlckvielakikceqywpleegqklvfgea
subfamily_CG42327_pd Subfamily CG42327 3-53 7.4e-09 29.7 In-house 87-139 (319) alignment 
Range on Protein: 3-53
Range on HMM: 87-139/319.0
DFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPGD--SVKFGNIRVELVS
||||.||. .  .|  .|.| |    .| .|.| | .      .|.|.| |  
dfwrtvweqqsrvivqltdlselGikvcaeylPtketldntslyGdilvtlkg
subfamily_Cele-PTP-14_pd Subfamily Cele-PTP-14 3-52 1.1e-08 29.1 In-house 109-157 (310) alignment 
Range on Protein: 3-52
Range on HMM: 109-157/310.0
DFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKpGDSVKFGNIRVELV
|||||..||   .| .. |  |  . ||  |||   | .  .| |||  .
dfwrmifqeraesilllckvgeegrpkcvgywpsl.gvtetygcirvtnl
subfamily_Cele-PTP-18_pd Subfamily Cele-PTP-18 3-46 8.4e-08 26.3 In-house 103-146 (305) alignment 
Range on Protein: 3-46
Range on HMM: 103-146/305.0
DFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPGDSVKFGN
||| | .|..| .| |. .|.|    || .|.. | .| ..| .
dfwymclqdkveaifmlcnllekgakkcleyfaskdkdvlefee
0044763 (Phosphotyrosine protein) phosphatases II 3-61 1.1e-07 27.2 In-house 39-76 (178) alignment 
Range on Protein: 3-61
Range on HMM: 39-76/178.0
DFWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPGdsvkfgnirvelvsleactggI
|..........|.| ..|. .|. ..|| .||| . |                     |
ddlellkelgithivnlteelelgflkcdpywpeeag.....................i
subfamily_Urchin-PTP-2_pd Subfamily Urchin-PTP-2 3-50 5.5e-06 20.0 In-house 251-294 (440) alignment 
Range on Protein: 3-50
Range on HMM: 251-294/440.0
DFWRMVWQENVTTIAMVTKLKegDKiKCGKYWPNKpGDSVKFGNIRVE
||||.| . ...|| |. .|.  ||  |  ||| .   || || . | 
dfwrlvhdyristiimlnqln..dk.tcsiywpvn.trsvtfgpftvg
0036282 (Phosphotyrosine protein) phosphatases II 4-46 1.5e-09 33.3 In-house 28-70 (174) alignment 
Range on Protein: 4-46
Range on HMM: 28-70/174.0
FWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPGDSVKFGN
||.|......||. |....|| .. ||  ||| .. | ...| 
fwemlkelgittvvmlleekelglykcinywpelredlerlgi
subfamily_eak_pd Subfamily eak 4-51 6.8e-06 19.7 In-house 109-156 (332) alignment 
Range on Protein: 4-51
Range on HMM: 109-156/332.0
FWRMVWQENVTTIAMVTKLKEGDKIKCGKYWPNKPGDSVKFGNIRVEL
||.|| ...  .| .. .  | .  |  ||.|.|  . .||| . || 
fwqmvleqkspaivqlledvelkleksdkyfpdktreelkfGildver
subfamily_Sponge-PTP4_pd Subfamily Sponge-PTP4 29-109 5.5e-06 20.2 In-house 93-173 (244) alignment 
Range on Protein: 29-109
Range on HMM: 93-173/244.0
KCGKYWPNKPGDSVKFGNIRVELVSLEACTGGIKRTMTMIEGIHCTFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDKSQ
.  . | |. | .. |   || |         |. ..    |  . .. || ||  |  ||| |... .   .|.|    .
npnnswknregaglpfdfnrvplskgsmgntyinasfvgclgrtaeyiltqhpladtsmdfwkmmlerhvnvlvvlgsvee
subfamily_PTPN14_pd Subfamily PTPN14 40-110 3.9e-08 27.6 In-house 57-130 (300) alignment 
Range on Protein: 40-110
Range on HMM: 57-130/300.0
DSVKFGNIRVELVSLEACT-GGIK--RTMTMIEGIHCTFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDKSQN
| . . . ||||.. .  . | |   .  . . | . .....| ||..|| ||| || ... . .||| .. ..
dvlPyednrvelsptkenstgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivmlteeeed
subfamily_ptpA1_pd Subfamily ptpA1 48-110 4.4e-09 30.6 In-house 63-126 (418) alignment 
Range on Protein: 48-110
Range on HMM: 63-126/418.0
RVELVSLEACTGGIKRTMTMIEGIHC-TFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDKSQN
||.|  ..   |        |.| .   |. || ||| |..||| || .|.   .|||. .|.|
rvqlkkiqdkegsdyinanyidgaypkqfictqgplpntiadfwrmvwenrcriivmlsresen
subfamily_Urchin-PTP-4_pd Subfamily Urchin-PTP-4 64-112 5.4e-11 36.5 In-house 77-127 (392) alignment 
Range on Protein: 64-112
Range on HMM: 77-127/392.0
TMTMIEGIHC--TFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDKSQNDK
  . |.....  .....|.| .....|||.|| .....|..|...  . ||
nasyipsfdnekayiasqgpnaaslddfwrmvfqenvttiamvtklkegdk
subfamily_PTPN1_pd Subfamily PTPN1 65-106 6.5e-09 29.9 In-house 63-104 (290) alignment 
Range on Protein: 65-106
Range on HMM: 63-104/290.0
MTMIEGIHCTFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLND
.  .| ..  .. || ||| ||. || || ..|  .||||| 
lveleeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnk
subfamily_Cele-PTP-15_pd Subfamily Cele-PTP-15 65-104 6.9e-08 26.8 In-house 67-106 (285) alignment 
Range on Protein: 65-104
Range on HMM: 67-106/285.0
MTMIEGIHCTFMTTQMPLPTTVSDFWSMVIDNKPSTVVML
| |    . |..||| ||| |.|||| |. ..| . |.||
mrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlml
subfamily_Urchin-PTP-1_pd Subfamily Urchin-PTP-1 67-112 2.6e-18 60.9 In-house 79-126 (315) alignment 
Range on Protein: 67-112
Range on HMM: 79-126/315.0
MIEGIHC--TFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDKSQNDK
 |.....  .....|.||...|.|||.||...|..|.||...|...||
yiksvdddkayiasqgPlkasvddfwrmvlqekvttivmvtkkqegdk
0045098 (Phosphotyrosine protein) phosphatases II 67-110 1.8e-10 36.1 In-house 58-101 (278) alignment 
Range on Protein: 67-110
Range on HMM: 58-101/278.0
MIEGIHCTFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDKSQN
.|.| . .|  || |||.||.||| |. ... ...|||..  ..
yidgypkkfIatqgPlpstvadfwrmlwelgitvivmltelvel
subfamily_Cele-PTP-20_pd Subfamily Cele-PTP-20 67-107 2.8e-07 24.5 In-house 88-128 (290) alignment 
Range on Protein: 67-107
Range on HMM: 88-128/290.0
MIEGIHCTFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDK
 ..|.. .|. || .|  || |.| ||...| ...||| . 
yvkGlkamfiltqGalkdtvidiwrmvlqekvaaivmlcel
subfamily_Urchin-PTP-5_pd Subfamily Urchin-PTP-5 68-112 8.6e-14 46.3 In-house 87-131 (297) alignment 
Range on Protein: 68-112
Range on HMM: 87-131/297.0
IEGIHCTFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDKSQNDK
..|..  ..||||| ..|| ||| ||.|...||.|||||....||
vkgnkhrlittqmPmkatvadfWamvldeqvstivmlnddnerdk
subfamily_PTPN6_pd Subfamily PTPN6 68-107 3.8e-08 27.7 In-house 93-132 (306) alignment 
Range on Protein: 68-107
Range on HMM: 93-132/306.0
IEGIHCTFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDK
..| ......||  |.|||||||.|| ...   .||.  .
vkgsdksyiatqgclettvsdFWrmvwqensrvivmttke
subfamily_Anemone-PTP-4_pd Subfamily Anemone-PTP-4 68-105 4.4e-06 21.1 In-house 40-77 (237) alignment 
Range on Protein: 68-105
Range on HMM: 40-77/237.0
IEGIHCTFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLN
..|   .....| || ..  ||| || ..| | .||| 
fdgtpkkyiaaqgplesscddfwqmvwqekcsvivmlt
subfamily_Urchin-PTP-6_pd Subfamily Urchin-PTP-6 69-112 4.3e-23 76.2 In-house 367-410 (515) alignment 
Range on Protein: 69-112
Range on HMM: 367-410/515.0
EGIHCTFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDKSQNDK
.||||||||||||||||||||||||..|||||.|||||||||||
kgihctfmttqmplpttvsdfwsmvlnnkpstivmlndksqndk
subfamily_Choan-PTP-2_pd Subfamily Choan-PTP-2 69-106 2.9e-07 24.7 In-house 60-97 (270) alignment 
Range on Protein: 69-106
Range on HMM: 60-97/270.0
EGIHCTFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLND
.| ........ |||||...|| |....| ...||. .
dgekkkYiaamgPlpttlksfwrmiweekvtaivmttg
0050432 (Phosphotyrosine protein) phosphatases II 70-111 4e-12 41.5 In-house 105-146 (308) alignment 
Range on Protein: 70-111
Range on HMM: 105-146/308.0
GIHCTFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDKSQND
.. ..|  || |||.|| ||| || ... ...|||..  .|.
klprkfIatqgPlpntvedFwrmvweqnvrvIvmLtklveng
0039614 (Phosphotyrosine protein) phosphatases II 70-111 1.5e-10 36.5 In-house 95-139 (297) alignment 
Range on Protein: 70-111
Range on HMM: 95-139/297.0
GI---HCTFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDKSQND
|      .|  || ||| || ||| || ... ...|||..   ..
gydlltrkfIatqgPlpetvedFwrmvweqgvtvivmLtklvelg
subfamily_Cele-PTP-19_pd Subfamily Cele-PTP-19 70-110 1.7e-07 25.3 In-house 87-127 (301) alignment 
Range on Protein: 70-110
Range on HMM: 87-127/301.0
GIHCTFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDKSQN
|    |..|| ||. |  ||| |..  .  ..|||  | ..
GhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvek
0046845 (Phosphotyrosine protein) phosphatases II 71-111 7.1e-12 40.7 In-house 75-115 (284) alignment 
Range on Protein: 71-111
Range on HMM: 75-115/284.0
IHCTFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDKSQND
|...|. ||.|||.|| ||| || ... ...|||..  .|.
ikkkfIatqgPlpntvedFwrmvweqnvrvIVmltelveng
subfamily_Anemone-PTP-2_pd Subfamily Anemone-PTP-2 71-111 5e-11 37.4 In-house 98-137 (298) alignment 
Range on Protein: 71-111
Range on HMM: 98-137/298.0
IHcTFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDKSQND
 . .|..|| ||..||.||| ||.... .|.|||..  . |
rn.afiatqaPltetvedFWrmvteedigtiVmltnleeld
0051299 (Phosphotyrosine protein) phosphatases II 72-111 5.8e-12 41.1 In-house 91-130 (288) alignment 
Range on Protein: 72-111
Range on HMM: 91-130/288.0
HCTFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDKSQND
 ..|. || |||.||.||| || ... ...|||..   ..
krkfIatqgPlpntvedFWrmvweqnvrvIvmltklvelg
0047943 (Phosphotyrosine protein) phosphatases II 72-111 1.4e-11 39.8 In-house 76-115 (273) alignment 
Range on Protein: 72-111
Range on HMM: 76-115/273.0
HCTFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDKSQND
  .|. ||.||| || ||| || ... ...|||..  ...
krkfiatqgPlpntvedfwrmvweqnvrviVmLtelvelg
0036941 (Phosphotyrosine protein) phosphatases II 72-111 5.8e-11 37.7 In-house 77-116 (297) alignment 
Range on Protein: 72-111
Range on HMM: 77-116/297.0
HCTFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDKSQND
  .|. || |||.|| ||| || ... ...|||..  ...
krkfIatqgPlpntvedFWrmvweqnvtvIvmltelvelg
0040439 (Phosphotyrosine protein) phosphatases II 72-110 3.2e-09 32.2 In-house 53-91 (249) alignment 
Range on Protein: 72-110
Range on HMM: 53-91/249.0
HCTFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDKSQN
  .|  || ||| ||.||| |. ... ...|||..  ..
krrfiatqgPlpetvedfwrmlwelgitvivmLtslvel
subfamily_PTPN12_pd Subfamily PTPN12 72-111 3e-08 27.9 In-house 82-121 (290) alignment 
Range on Protein: 72-111
Range on HMM: 82-121/290.0
HCTFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDKSQND
..... .| |||.|..||| |... . . |||.  .  ..
kleyiaaqgPLpktlddfWrmiweknveivvmaCrevelg
subfamily_Ptp69D_pd Subfamily Ptp69D 72-110 3.5e-08 27.9 In-house 90-128 (307) alignment 
Range on Protein: 72-110
Range on HMM: 90-128/307.0
HCTFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDKSQN
. .|.. | |. .|. ||| |. . .  ..||| . .. 
kkkfiaaqdPveatigDfWRmiaeqevtlivmlsnltek
subfamily_PTPN3_pd Subfamily PTPN3 72-107 9.9e-08 26.2 In-house 83-118 (280) alignment 
Range on Protein: 72-107
Range on HMM: 83-118/280.0
HCTFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDK
   ...|| ||..|..||| || ..| |..||| . 
vnryiatqGPlaktatdfWqmvweqksslivmlttl
subfamily_egg_pd Subfamily egg 72-110 1e-07 25.9 In-house 82-120 (307) alignment 
Range on Protein: 72-110
Range on HMM: 82-120/307.0
HCTFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDKSQN
  .|. .| ||  || ||| ||  ..   .|||. . ..
lnefilaqaplkntvddfwrmvfqeevqyivmltsrkes
0041856 (Phosphotyrosine protein) phosphatases II 72-106 1.7e-06 23.3 In-house 33-67 (182) alignment 
Range on Protein: 72-106
Range on HMM: 33-67/182.0
HCTFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLND
...|  || ||. || ||. |. ... .|.|.|..
atrfiatqgpllstvadflrmlkelgittivnlte
subfamily_Cele-PTP-17_pd Subfamily Cele-PTP-17 72-106 3.8e-06 20.7 In-house 84-118 (347) alignment 
Range on Protein: 72-106
Range on HMM: 84-118/347.0
HCTFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLND
.  .. || ||| || ||| ||   | . || . .
skeyiltqyplpdtvrdfwkmvsvtkvtqvvtife
subfamily_PTPRN_pd Subfamily PTPRN 72-111 4.2e-06 20.7 In-house 99-138 (297) alignment 
Range on Protein: 72-111
Range on HMM: 99-138/297.0
HCTFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDKSQND
. ....|| ||..||.||| || ..    .|.|   ....
apayiatqgplastvadfwqmvweqGvvvivnltrleeeg
0043147 (Phosphotyrosine protein) phosphatases II 72-107 5.1e-06 21.8 In-house 19-54 (172) alignment 
Range on Protein: 72-107
Range on HMM: 19-54/172.0
HCTFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDK
 . |  || ||. |..||| |. ... ...|.|.. 
pdrfiatqgplrntladfwrmlkelgithivnltel
Y_phosphatase Protein-tyrosine phosphatase 73-110 5.8e-11 37.6 Pfam-A 42-79 (235) alignment 
Range on Protein: 73-110
Range on HMM: 42-79/235.0
CTFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDKSQN
 .|. ||.||. |..||| ||...| ...|||..  ..
kkfIatQgPlkstiedFWrmvwqekvkvivmltsleek
Y_phosphatase Protein-tyrosine phosphatase 73-110 5.8e-11 37.6 In-house 42-79 (235) alignment 
Range on Protein: 73-110
Range on HMM: 42-79/235.0
CTFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDKSQN
 .|. ||.||. |..||| ||...| ...|||..  ..
kkfIatQgPlkstiedFWrmvwqekvkvivmltsleek
0045450 (Phosphotyrosine protein) phosphatases II 73-111 2.1e-10 36.3 In-house 107-145 (307) alignment 
Range on Protein: 73-111
Range on HMM: 107-145/307.0
CTFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDKSQND
 .|. || ||| || ||| |. ... ...|||..   ..
rkfIatqgPlpetvedFwrmlweqgvtvivmltelvelg
0043336 (Phosphotyrosine protein) phosphatases II 73-111 2.4e-10 35.8 In-house 88-126 (278) alignment 
Range on Protein: 73-111
Range on HMM: 88-126/278.0
CTFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDKSQND
 .|  || ||| || ||| || ... .|.|||..   ..
rkfiatqgPlpetvedFwrmvwelgvttivmLtelvelg
0042113 (Phosphotyrosine protein) phosphatases II 73-111 1.5e-08 29.9 In-house 52-90 (245) alignment 
Range on Protein: 73-111
Range on HMM: 52-90/245.0
CTFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDKSQND
 .|  || ||| || ||| |. ... .|.|||..   ..
pkfiatqgPlpetvedfwrmlwelgittivmLteeeelg
subfamily_Sponge-PTP9_pd Subfamily Sponge-PTP9 73-110 6.4e-08 26.6 In-house 85-122 (301) alignment 
Range on Protein: 73-110
Range on HMM: 85-122/301.0
CTFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDKSQN
  |. .| |.  |. ||| .....||...||. .. ..
kkfiaaqgpmkktlvdfWrliwqekpvsivmvtnlkeg
subfamily_PTPN5_RR_pd Subfamily PTPN5_RR 73-106 7.3e-08 26.8 In-house 73-106 (274) alignment 
Range on Protein: 73-106
Range on HMM: 73-106/274.0
CTFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLND
 ... || |||.||.||| |.  .. . .||| .
kayvatqGPlpntvadfWrmiyqeevqvivmltk
0049260 (Phosphotyrosine protein) phosphatases II 73-110 7.6e-07 24.4 In-house 9-46 (152) alignment 
Range on Protein: 73-110
Range on HMM: 9-46/152.0
CTFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDKSQN
  |. || |.| |..||| |. ... .|.|||.. . .
fefiatqgpgpntladfwrmlkelgittivmltellel
subfamily_Choan-PTP-4_pd Subfamily Choan-PTP-4 73-106 9.1e-06 19.7 In-house 76-109 (297) alignment 
Range on Protein: 73-106
Range on HMM: 76-109/297.0
CTFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLND
  .. .| || .|| ||| .| ..   ..||.  
lkyilaqGplsatvddfwtlvaeqdvrvivmvak
DSPc_SM00195 74-111 6.2e-12 40.8 In-house 70-107 (263) alignment 
Range on Protein: 74-111
Range on HMM: 70-107/263.0
TFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDKSQND
..  ||.|||.||.||| ||...| ...|||.. ..|.
kyIatQgPlpstvedFWrmvweekvkiivmlteeeeng
PTPc_SM00194 74-111 6.2e-12 40.8 In-house 70-107 (263) alignment 
Range on Protein: 74-111
Range on HMM: 70-107/263.0
TFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDKSQND
..  ||.|||.||.||| ||...| ...|||.. ..|.
kyIatQgPlpstvedFWrmvweekvkiivmlteeeeng
subfamily_PTPN23_pd Subfamily PTPN23 74-110 2.4e-10 34.7 In-house 84-120 (288) alignment 
Range on Protein: 74-110
Range on HMM: 84-120/288.0
TFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDKSQN
.|..|| ||..|..|||.|| ..| |..||| .|.. 
dfiatqaPlqstlnDFWlmvyeqkssviVmllskeel
0040438 (Phosphotyrosine protein) phosphatases II 74-111 2.6e-10 35.6 In-house 87-124 (317) alignment 
Range on Protein: 74-111
Range on HMM: 87-124/317.0
TFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDKSQND
.|  || ||| || ||| || ... ...|||..  ...
kfIatqgPlpntvedFwrmvweqgvtvivmLteleelg
subfamily_Sponge-PTP8_pd Subfamily Sponge-PTP8 74-111 4.7e-10 34.1 In-house 90-127 (305) alignment 
Range on Protein: 74-111
Range on HMM: 90-127/305.0
TFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDKSQND
.....| ||..||.||| .... |.||.||| .  ...
kyivaqgPlkntvadfWrliveekvstivmltklvegg
subfamily_Urchin-PTPRB-like_pd Subfamily Urchin-PTPRB-like 74-107 6.7e-10 33.5 In-house 91-124 (288) alignment 
Range on Protein: 74-107
Range on HMM: 91-124/288.0
TFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDK
....|| ||. || ||| .| .|| ||.|||.. 
kyiatqgPladtvndfWelvyenktstivmltel
subfamily_PTPRD_pd Subfamily PTPRD 74-109 8.7e-10 32.8 In-house 92-127 (564) alignment 
Range on Protein: 74-109
Range on HMM: 92-127/564.0
TFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDKSQ
... || ||..|..||| || ... ||.|||.  . 
ayIAtqgPlaetiedFWRmvweqnsstiVmltkleE
subfamily_Nvec-PTP-2_pd Subfamily Nvec-PTP-2 74-111 1.3e-09 32.6 In-house 53-90 (250) alignment 
Range on Protein: 74-111
Range on HMM: 53-90/250.0
TFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDKSQND
.|..|| ||..|. ||| ||...| .|.|||.. ....
afiatqgPlqatiedfWrmvleeksgtivmLtnLkese
subfamily_PTPRB_pd Subfamily PTPRB 74-106 1.5e-09 32.3 In-house 95-127 (293) alignment 
Range on Protein: 74-106
Range on HMM: 95-127/293.0
TFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLND
 |..|| |||.|| ||| || ..| |..||| .
efiatqGPlpetvddfWrmvwekkssiivmltq
subfamily_Urchin-PTP-3_pd Subfamily Urchin-PTP-3 74-111 2.7e-09 31.6 In-house 92-129 (325) alignment 
Range on Protein: 74-111
Range on HMM: 92-129/325.0
TFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDKSQND
.|...|.||..|. |.| .|.| . | ||.||   ...
vflaaqaPltatindlWrlvldWrcsvvvvlneldlgk
subfamily_Urchin-PTP-2_pd Subfamily Urchin-PTP-2 74-107 3.5e-09 30.5 In-house 237-270 (440) alignment 
Range on Protein: 74-107
Range on HMM: 237-270/440.0
TFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDK
.|..||||| .|| ||| .| | . ||..|||. 
afiatqmpldstvldfwrlvhdyristiimlnql
subfamily_Urchin-PTP-7_pd Subfamily Urchin-PTP-7 74-112 4e-09 30.8 In-house 93-131 (315) alignment 
Range on Protein: 74-112
Range on HMM: 93-131/315.0
TFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDKSQNDK
 ....| |....| ||| .| ... ...|||..  ...|
ryiaaqgpnvasvkdfwrlvfeedigkivmltnlvegek
subfamily_PTPRK_pd Subfamily PTPRK 74-107 5e-09 30.4 In-house 87-120 (314) alignment 
Range on Protein: 74-107
Range on HMM: 87-120/314.0
TFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDK
 |. || ||. || ||| .| |.. ...|||.. 
afivtqgPlqetvkdfWrlvydencasivmltel
subfamily_Anemone-PTP-5_pd Subfamily Anemone-PTP-5 74-110 5.7e-09 30.5 In-house 92-128 (319) alignment 
Range on Protein: 74-110
Range on HMM: 92-128/319.0
TFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDKSQN
 |. || || .|..||| || ... |.||||.. ...
kfiatqaPlentiedfWrmvWeeessivvmltklvek
subfamily_Sponge-PTP5_pd Subfamily Sponge-PTP5 74-106 2.4e-08 28.2 In-house 76-108 (283) alignment 
Range on Protein: 74-106
Range on HMM: 76-108/283.0
TFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLND
 .. .| ||  || ||| || |.| ...|||  
kyiiaqsPldrtvvdfWkmvfdekitaivmltk
subfamily_Anemone-PTP-6_pd Subfamily Anemone-PTP-6 74-108 2.5e-08 28.4 In-house 90-124 (318) alignment 
Range on Protein: 74-108
Range on HMM: 90-124/318.0
TFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDKS
... .| ||| |..||| || . . ...||| ...
ayiaaqaPlpetieDfWrmvWeqnsavivmltqee
subfamily_PTPRG_pd Subfamily PTPRG 74-110 2.6e-08 27.5 In-house 92-128 (563) alignment 
Range on Protein: 74-110
Range on HMM: 92-128/563.0
TFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDKSQN
 |..|| ||..|. ||| |. ... ...||. .  ..
afiatqgplkdtfddFWrmiWeqnvaiivmitnlver
0037934 (Phosphotyrosine protein) phosphatases II 74-108 4.1e-08 28.6 In-house 45-83 (243) alignment 
Range on Protein: 74-108
Range on HMM: 45-83/243.0
TFMTTQMPLPTTVSD----FWSMVIDNKPSTVVMLNDKS
..  ||.||| || |    || |. ... ...|||..  
rliatqgPlpetveddlasfwrmlwelgitvivmltelv
subfamily_Sponge-PTP11_pd Subfamily Sponge-PTP11 74-111 8.2e-08 26.4 In-house 92-129 (290) alignment 
Range on Protein: 74-111
Range on HMM: 92-129/290.0
TFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDKSQND
 .. || |.. |. |||... ..| . .||| .  ...
qyiatqgpvsntlvdFWkliwqekvtiivmltniieeg
subfamily_Fungi-PTP1_pd Subfamily Fungi-PTP1 74-110 1.1e-07 26.0 In-house 105-141 (350) alignment 
Range on Protein: 74-110
Range on HMM: 105-141/350.0
TFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDKSQN
 .. || ||| || ||. ... ||   ...|...  .
kYiatqaPlpstvddfykvillnkvkvilsltsdvel
subfamily_Urchin-PTP-8_pd Subfamily Urchin-PTP-8 74-106 2.5e-07 25.5 In-house 69-102 (284) alignment 
Range on Protein: 74-106
Range on HMM: 69-102/284.0
TFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLN-D
 ...|| ||. |. ||| |. . . ||.|.|  |
kyiatqGPldntladfWrmiweyncstivlltkd
subfamily_Sponge-PTP10_pd Subfamily Sponge-PTP10 74-111 2.9e-07 24.7 In-house 87-124 (287) alignment 
Range on Protein: 74-111
Range on HMM: 87-124/287.0
TFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDKSQND
 |. .. |.  |. .|| .. |......||| .. .||
afiiaesPmfntarnfWkliddrnvtaivmlcqekend
subfamily_Choan-PTP-1_pd Subfamily Choan-PTP-1 74-108 3e-07 24.8 In-house 85-119 (281) alignment 
Range on Protein: 74-108
Range on HMM: 85-119/281.0
TFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDKS
 ...|| |.|... .|| ||...| |..||.  . 
eyiatqgPvPaslvafWqmvweqkvsaivmvtrei
subfamily_Urchin-PTPRA_pd Subfamily Urchin-PTPRA 74-106 3.5e-07 24.8 In-house 105-138 (319) alignment 
Range on Protein: 74-106
Range on HMM: 105-138/319.0
TFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLN-D
 ....| ||. |. ||| |. . . ||.|.|  |
kyiaaqGPldntladfWrmiweyncstivlltkd
subfamily_PTPRA_pd Subfamily PTPRA 74-106 4.5e-07 24.0 In-house 102-134 (330) alignment 
Range on Protein: 74-106
Range on HMM: 102-134/330.0
TFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLND
.|...| |.  || ||| |. . | .|.||| .
kfiaaqGPkeetvedfwrmiweqksativmlte
subfamily_Fungi-PTP2_pd Subfamily Fungi-PTP2 74-110 4.7e-07 23.4 In-house 108-144 (349) alignment 
Range on Protein: 74-110
Range on HMM: 108-144/349.0
TFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDKSQN
 ...||.|||.|| ||. ... |.   |. |||  ..
kyiatqaPlPstvddfykvillngvklvlsLnddkel
subfamily_CG7180_pd Subfamily CG7180 74-108 7.2e-07 23.1 In-house 86-120 (296) alignment 
Range on Protein: 74-108
Range on HMM: 86-120/296.0
TFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDKS
 .. |..|   || .||..| |.. |.||.| .. 
eyivteapkketvdefWrlvydeeisavvvLtktf
subfamily_PTPN9_pd Subfamily PTPN9 74-105 8.8e-07 23.2 In-house 86-117 (297) alignment 
Range on Protein: 74-105
Range on HMM: 86-117/297.0
TFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLN
.|..|| ||. |||||| || ...  ..||  
afiatqGplkktvsdfWrmvWeqevlvivmtt
subfamily_Choan-PTP-3_pd Subfamily Choan-PTP-3 74-105 1.2e-06 22.6 In-house 81-112 (287) alignment 
Range on Protein: 74-105
Range on HMM: 81-112/287.0
TFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLN
.|...| |...|| ||| .|.... ..|... 
afiaaqgPiaatvrdfwravletrsasvitmt
subfamily_Cele-PTP-10_pd Subfamily Cele-PTP-10 74-106 2e-06 21.7 In-house 97-129 (305) alignment 
Range on Protein: 74-106
Range on HMM: 97-129/305.0
TFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLND
 |. .| ||  |. .|| |||.||   .|||  
rficaqgpldqtidefwwmviqnkveqivmlck
subfamily_Anemone-PTP-3_pd Subfamily Anemone-PTP-3 74-111 2.7e-06 21.7 In-house 6-43 (199) alignment 
Range on Protein: 74-111
Range on HMM: 6-43/199.0
TFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDKSQND
 ...|| ||  |..||| || .     .||.||  .| 
ryiatqhplretmadfwqmvwetgsghivmvnddqknk
subfamily_Nvec-PTP-3_pd Subfamily Nvec-PTP-3 74-111 2.7e-06 21.7 In-house 5-42 (198) alignment 
Range on Protein: 74-111
Range on HMM: 5-42/198.0
TFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDKSQND
 ...|| ||  |..||| || .     .||.||  .| 
ryiatqhplretladfwqmvwetgsghivmvnddqknk
0046846 (Phosphotyrosine protein) phosphatases II 74-107 7.5e-06 21.3 In-house 24-57 (176) alignment 
Range on Protein: 74-107
Range on HMM: 24-57/176.0
TFMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDK
 . .|| ||| |. ||. |. ... ..||.|.. 
rpiatqgplprtladflemlkelgitavvnltee
subfamily_PTPN13_pd Subfamily PTPN13 75-109 6.9e-07 23.8 In-house 79-113 (273) alignment 
Range on Protein: 75-109
Range on HMM: 79-113/273.0
FMTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDKSQ
.. .| |||.||.||| || . | . ..|.  . .
yiacqGPlPetvkdfwqmvweqkaeviamvtleke
subfamily_Cele-PTP-16_pd Subfamily Cele-PTP-16 76-109 1.8e-06 21.8 In-house 86-119 (303) alignment 
Range on Protein: 76-109
Range on HMM: 86-119/303.0
MTTQMPLPTTVSDFWSMVIDNKPSTVVMLNDKSQ
. ||.||. | .||| |.|..|   |..|   |.
iltqlplshtaadfwqmiieqkvkcvlllltdse