Gene MTMR1-4 in Amphimedon queenslandica

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family Myotubularin
Subfamily MTMR1
Protein sequence
ID Type Fasta BLAST phosphatome Note
AqueP025_AA protein Get Run
AqueP025_AA_219-605 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_MTMR1_pd Subfamily MTMR1 216-604 8.4e-205 672.4 In-house 2-389 (389) alignment 
Range on Protein: 216-604
Range on HMM: 2-389/389.0
YPDDGWEVYDPEAELKRMGVGNDGvPWRICHLNKNYELCDTYTSTFSVPLNCSDEMVQGVAQFRSKGRIPVLSWLHPVTQASITRCSQPLVGTMNRRSKE
. .|||.||||||||.|.|. |.   |||..|||.|||||||.....||...|||....||.||||||.||||||.. .||.|.|.||||||....||||
lkedGWkvydpeaelerlgllnek.lWritklnkkyelcdtYpavlvvpkvvsdedlkkvaafrskgRlPvlswlnkenqavilrasqplvGlsgkrske

DEQYMQEILKANDKSNKLYILDARPKINAMTNVAMGGGYEHEDCYVNMDFSFLDIGNIHVMRESLKKLREICYPDVDDQRWFSNLESSHWLDHIKAILCG
||.|.|.||.||..|.||.|||||...||..| |.|.|||.|..|.|... ||||.||||.|||||||.|...|.|||..|.|.|||..||.|||.||.|
dekylqaileanaqsekllildarssvnavankakgkgyeseeaYknaelifldihnihvvReslkklkelvlpnvddkkwlsalestkWlehiklilag

AVKVVECVETHKSSVVVHCTDGWDRTAQITSLSMLMMDSYFRTIKGFEVLVEKEWLGCGHKFSQRTGHGDKNHSDDQRSPIFLQFIDCVWQLMEQFPTAF
|||.||.|||.|.||.|||.||||||||.|||.||..|||.|||.|||||.||||| .||||..|.||||||.||..|||.|||||||||||..||||||
avkivekvetektsvlvhcsdGWDRtaqltsLamlllDsyyRtieGfevliekeWlsfGHkfkeRlghgdknssdaersPvFlqfiDcvwqltrqfptAF

EFNEHFLITILDHLYSCLFGTFLFNCERLRVEAGVKDKTVSLWSFVNSQIDVYKNPLYAELMNNKVLFPRTSIRILKLWTGYYMRWNPR
||||.||||.|||||||||||||||.|. ||.. ||.|||||||.|||. . ..|||||| ...|||.|..|.| |.||. ||.|||||
efneefLitlldhlysclfGtflfnsekervkekvkektvslwsyvnsskeeftnplyaeelekkvlypkaslrrlelWkeyylrwnpr
subfamily_Dicty-MTMR1-like_pd Subfamily Dicty-MTMR1-like 217-602 2.8e-157 516.0 In-house 12-403 (404) alignment 
Range on Protein: 217-602
Range on HMM: 12-403/404.0
PDDGWEVYDPEAELKRMGVGNDGvPWRICHLNKNYELCDTYTSTFSVPLNCSDEMVQGVAQFRSKGRIPVLSWLHPVTQASITRCSQPLVGTMNRRSKED
 .||| .||.| | ||.|. ..  .||| ..|..||||.|| ... || ..||| .. ||.|||||||||||| |. ....|||.||||||  ..||.||
ledgwliydaeeEykRlgikses.eWriskinsdyelcetYPkllvvPesisDeelkkvasfRskgRiPvlswrhrsknstitRssqplvGltksrseed

EQYMQEILKANDKSNKLYILDARPKINAMTNVAMGGGYEHEDCYVNMDFSFLDIGNIHVMRESLKKLREICYPDVDD-QRWFSNLESSHWLDHIKAILCG
|.... | ||. ....|||||||||.||..| |.| |||. . | | . .|| | ||| .|||||||....   ... . |.|.||||.|||||| .| |
EklinsirkaktqletlyildarpkanavansakgagyedisryenceieflnienihelreslkklkkavnsiiekeknwlselessrWldhikllleg

AVKVVECVETHKSSVVVHCTDGWDRTAQITSLSMLMMDSYFRTIKGFEVLVEKEWLGCGHKFSQRTGHgDKNHSDDQRSPIFLQFIDCVWQLMEQFPTAF
. ..|| .|..||||.||| ||||||.|..|||.|..|.|.|||.||.||.|||||  |||| ||.|.  ...|.|.||||||||||||.||..|||| |
skriveliekekssvlvhcsdgwDrtsqlsslsqllldpyyrtiegFivliekewlsfGhkfaqRigq.ttekssdersPiflqFidcvyqltkqfptsF

EFNEHFLITILDHLYSCLFGTFLFNCERLRVEAGVKDKTVSLWSFVNSQIDVYKNPLY--AELMNNKVLFPRT-----SIRILKLWTGYYMRWN
||||.|||.|||.|||| |||||...|. |... .. .|||||. .... . | ||||   .  ...  .  .     .|. .|||  ||.||.
eFnekflikildalyscrfgtFLydsekeRqqnnlaketvslWalleankseylnplyilekkeqkenitssessssadikliklWseyylrwr
0040695 (Phosphotyrosine protein) phosphatases II 218-603 2.1e-153 504.4 In-house 5-387 (388) alignment 
Range on Protein: 218-603
Range on HMM: 5-387/388.0
DDGWEVYDPEAELKRMGVGNDgvPWRICHLNKNYELCDTYTSTFSVPLNCSDEMVQGVAQFRSKGRIPVLSWLHPVTQASITRCSQPLVGTMNRRSKEDE
 .|| .||.. ||||.|.|.|  .|||...|.|||||..| . . ||  .|||... ||.|||||||||||. || ..|...|.||||||....||.|||
eegwslydilrelkrlglgld..lwrisivNenyelcpsYPallvVPksisdellkrvarfrskgriPvlsyrhpnngavllRssqplvglllsrslede

QYMQEILKANDKSNKLYILDARPKINAMTNVAMGGGYEHEDCYVNMDFSFLDIGNIHVMRESLKKLREICYPDVDDQRWFSNLESSHWLDHIKAILCGAV
.....|||.. ...||.|.|.|||.||..|.|.|||.| || | |... ||.| ||||.||||.||...|.. .|.....| ||.|.|||.|| || .||
klleailkllpnlskllivdlrpklnalanralgggvenedaypnaeliflnipnihvvreslqklldaclnvpdslnllslleesgwldliklilelav

KVVECVETHKSSVVVHCTDGWDRTAQITSLSMLMMDSYFRTIKGFEVLVEKEWLGCGHKFSQRTGHGDKNHSDDQRSPIFLQFIDCVWQLMEQFPTAFEF
 .|....  .|||.|||.||||||.|..||..|..|.|.||..|| ||.|||||  ||||..|.||..........||.||.|.||||||. ||||||||
livklldlgnssvlvhcsdgwdrtsqlssLaqllldPyYRTleGFqvLiekeWlsfghkfadRlghleseidskefsPvFllFLdcvwqLlrqfPtaFeF

NEHFLITILDHLYSCLFGTFLFNCERLRVEAGVKDKTVSLWSFVNSQIDVYKNPLYAELMNNkVLFPRTSIRILKLWTGYYMRWNP
||..|....||||||.|||||||.|. |.|..| ..|.||||...|. ....||||    .  ||.| .|.. |.||..||.||.|
nerlLlfLadhlyscrfgtFlfnsekerlelsvsertlslwsyllsrkseflnplYdpssle.vllpslsvldlllWleyylrwlp
subfamily_MTMR6_pd Subfamily MTMR6 208-602 3.1e-152 499.5 In-house 2-396 (397) alignment 
Range on Protein: 208-602
Range on HMM: 2-396/397.0
YAFHFRG----DYPDDGWEVYDPEAELKRMGVGNDgvPWRICHLNKNYELCDTYTSTFSVPLNCSDEMVQGVAQFRSKGRIPVLSWLHPVTQASITRCSQ
|||...     .   .||. .| .||..|||| |.   | ...|||.|||||||.... || . . |.. | ..||||||.||||.||  ..|.| ||||
yafsykpkkdkeekvsGwklldlkaeytrmgvpne..kwtltdlnkdyelcdtyprelyvPksatkevlvgsskfrskgrlPvlsylhkeneaaicrcsq

PLVGtMNRRSKEDEQYMQEILKANDKSNKLYILDARPKINAMTNVAMGGGYEHEDCYVNMDFSFLDIGNIHVMRESLKKLREICYPDVDDQ-RWFSNLES
|| | ...|..|||. .. | ||| .|. ||..|.|||.||..| | | |||.|| | |. | |..| |||||||||.|| |..  .  ..  ..| |||
plsg.fsarcledeklleairkanpnsellyvvdtrpklnalankaagkGyenednysnikfqfvgienihvmreslqkllevvelksksvseflsgles

SHWLDHIKAILCGAVKVVECVETHKSSVVVHCTDGWDRTAQITSLSMLMMDSYFRTIKGFEVLVEKEWLGCGHKFSQRTGHGDKNhsDDQRSPIFLQFID
| || ||||.|  .. . . |.... ||.|||.||||||||..||. |..|.|.|||||| ||.|||||. |||||.|.|. |..    . ||||.||..
sgwlkhikavldasifiakavaeegasvlvhcsdGwdrtaqvcslasllldpyyrtikGflvliekewlsfGhkfsercGllded..skevsPiftqfle

CVWQLMEQFPTAFEFNEHFLITILDHLYSCLFGTFLFNCERLRVEAGVKDKTVSLWSFVNSQIDVYKNPLYAELMNNKVLFPRTSIRILKLWTGYYMRWN
|||||.||||.||||||.||... ||.||| ||||| |||. | .. .|..| |||... .. | | |||| . ....|| | |.   ||||.. |.|..
cvwqlleqfpkafefnerfllelhdhvyscqfGtflgncekdrrdlklkertkslwayllerkddylnplykaetekevlkpdtapaalklwralynrfd
Myotub-related Myotubularin-like phosphatase domain 217-547 1.2e-143 471.2 Pfam-A 17-352 (353) alignment
Myotub-related Myotubularin-like phosphatase domain 217-547 1.2e-143 471.2 In-house 17-352 (353) alignment
subfamily_MTMR9_pd Subfamily MTMR9 215-602 5.8e-118 386.4 In-house 9-393 (393) alignment 
Range on Protein: 215-602
Range on HMM: 9-393/393.0
DYPDDGWEVYDPEAELKRMGVGNDGvpWRICHLNKNYELCDTYTSTFSVPLNCSDEMVQGVAQFRSKGRIPVLSWLHPVTQASITRCSQPLVGTMNRRSK
.  .||.. .|.| |.... .  |.  ||| . |||...| .| ... || . .|| .. .|.||..||.||||.||  |.| . |.||||.|. ..| |
tiledgysafdrenefaklisasde..wRissvNknfkvcasypesvivPkaiddeelkasaafreggrfPvLsylhketkavllrssqplcgssgkrck

EDEQYMQEILKANdksNKLYILDARPKINAMTNVAMGGGYEHEDCYVNMDFSFLDIGNIHVMRESLKKLREICYP-DVDDQRWFSNLESSHWLDHIKAIL
|||. .. .||..   .| .|.| | |  |... . ||| | |. |...  .  .. ..... .|| || | |    .. ....|.||.| ||......|
edekllnlvlkkl...kkGlivdtrsksaaenarskgggietevkysqwkkasrslesvasiqdslaklleacsdaglstdkflsrleksgwlsqvadll

CGAVKVVECVETHKSSVVVHCTDGWDRTAQITSLSMLMMDSYFRTIKGFEVLVEKEWLGCGHKFSQRTGHGD-KNHSDDQRSPIFLQFIDCVWQLMEQFP
  |..|..|.......|||| ..| | | |.|||..|..|...||..||| |.|.||.  || |..|. .   |........|.|| |.|||.|...|||
eaalvvaqcldeegapvvvhgeeGlDatlqvtsLaqlildpdaRtvrgfealiereWiqaGHPFasRaskvaaketkkklsgpvfllFLDcvyqilsqfp

TAFEFNEHFLITILDHLYSCLFGTFLFNCERLRVEAGVKDKTVSLWSFVNS--QIDVYKNPLYAElmNNKVLFPRTSIRILKLWTGYYMRWN
 .|||||..||..  | ||. ||||| ..|. | |...| |||||||.||.  ... . |||| .  |..|. |      |.||.. |.||.
asFEFneelLillfehsyssqfgtflcdneaerkelklkkktvslwsyvnrpeklkqflnplyea..naeviwpsvapqslelWselylrwq
subfamily_Ank-MTMR1_pd Subfamily Ank-MTMR1 219-601 1.8e-111 364.8 In-house 14-404 (405) alignment 
Range on Protein: 219-601
Range on HMM: 14-404/405.0
DGWEVYDPEAELKRMGVGND----G-VPWRICHLNKNYELCDTYTSTFSVPLNCSDEMVQGVAQFRSKGRIPVLSWLHPVTQASITRCSQPLVGTMNRRS
||||||. . |  |. .  |    . . |..  .||.|..| .|.|.. |  .. |  .. .  |||||||| |||  | ..|||.||||||||    | 
dgwevynqkkeylrfniyideenssncywkvtsinkeykmcssyssslvvlskaldkdlekifsfrskgripslswkdpssnasisrcsqplvgierarc

KEDEQYMQEIlKANDKSNKLYILDARPKINAMTNVAMGGGYEHEDCYVNMDFSFLDIGNIHVMRESLKKL--------REICYPDVDDQRWFSNLESSHW
 ||| |  ..      |. ||..|||||.||..| | | |.|    | |  . |..| ||||.| ||.||        |.  . .  | |..  .| . |
pedelycssl.alsapsktlylidarpklnaiantangagfenihnypncklvfmnipnihvirksleklvlamkssardkdhtestdmrfwgyieetgw

LDHIKAILCGAVKVVECVEtHKSSVVVHCTDGWDRTAQITSLSMLMMDSYFRTIKGFEVLVEKEWLGCGHKFSQRTGHGDKNhsDDQRSPIFLQFIDCVW
. |||.||  |    | .  .  |..|||.|||||| |||||. ...| |.|||.||.||.|||||  ||||| | ||   |  ...||||| ||.||..
ishiksileaatfsaelil.kgnsilvhcsdgwdrtpqitsltqilldpyyrtivgfqvliekewlsfghkfslrlghlpgn..eeerspifqqfldccf

QLMEQFPTAFEFNEHFLITILDHLYSCLFGTFLFNCERLRVEAGVKDKTVSLWSFVNSQIDVYKNPLYAElMNNKVLFPRTSIRILKLWTGYYMRW
||..|||  |||   .|. | | ..|| .|||| |||. ||.  || ||.|.|| || ... . || |    . . . |.   | |.||   ||| 
qllsqfpllfeftpslllfisdnihsckygtflnncekdrvqdqvktktisiwsevnlnvnkflnpyynp.qdiqsikpklysrclelwkacymrv
subfamily_MTMR3_pd Subfamily MTMR3 328-599 3e-104 342.2 In-house 170-440 (442) alignment 
Range on Protein: 328-599
Range on HMM: 170-440/442.0
DKSNKLYILDARPKINAMTNVAMGGGYEHEDCYVNMDFSFLDIGNIHVMRESLKKLREICYPDVDDQRWFSNLESSHWLDHIKAILCGAVKVVECVETHK
....|| |.|||    |..| | |||.|.|. | | .  ||...||| .|.|...||...    |...|.|.||. .|| ..  .|  |||||| |....
eekkkllivdarsytaafanrakgGGceleeyypncevvflglanihavrksfnslrallsqspdesnwlsalektkWlqnlsvllkaavkvveavdkeg

SSVVVHCTDGWDRTAQITSLSMLMMDSYFRTIKGFEVLVEKEWLGCGHKFSQRTGHGDKNHSDDQRSPIFLQFIDCVWQLMEQFPTAFEFNEHFLITILD
 .|.|||.||||||.||..|. |..| |.||..||.||||.|||  ||||. |.|||.. .  ..|.|.|||..|.| || .||||.||||| ||. .. 
rpvlvhCsdGWdrttqivalakllldpyyrtleGfkvlvereWldfGhkfadrcghgenvddanercPvflqwldavhqlqrqfPtsfefneaflvklvq

HLYSCLFGTFLFNCERLRVEAGVKDKTVSLWSFVNSQIDVYKNPLYAELmNNKVLFPRTSIRILKLWTGYYM
| |||||||||.|.|. | |  ||..|.|.||..... . |.| ||.|  ...||.| .|.| ||||.  |.
htysclfGtflansekereeekvkertlsvWsllrakekeyrnllykek.teavllpavsvrelklwsevyl
subfamily_MTMR5_pd Subfamily MTMR5 357-599 5.6e-67 218.6 In-house 222-479 (483) alignment 
Range on Protein: 357-599
Range on HMM: 222-479/483.0
EDCYVNMDFSFLDIGNIHVMRESLKKLREICYPDVD-----DQRWFSNLESSHWLDHIKAILCGAVKVVECVETHKSSVVVHCTDGWDRTAQITSLSMLM
 . . ...|  ... .|  .. |.|||. .| |. .      | . . .| | ||  |...|  .. ||. .. ..|||.|   |||| |||..||. |.
sevdskaefipvelveirqvkasfkkllraClpstaveeaesqsFlksvedseWlqqissllqlsgavvdlldlqgssvlvslEdGwdvtaqvsslaqll

MDSYFRTIKGFEVLVEKEWLGCGHKFSQRTGHGdKNHSDDQRSPIFLQFIDCVWQLMEQFPTAFEFNEHFLITILDHLYSCLFGTFLFNCERLRVEAGV-
.|.|.||..||.||||||||. ||.|..|. .  ....    .|.||||.|||.|...|||.|||||...| ..  |  |. | |||...|  |.|.|. 
ldpyYRtleGFkvLveKEWLafGHrFtkrsnqt.lsaqssgfaPvFlqFLDcvhqvsrqfPlafefndfylkflayhsvsnrfrtfllDseyerlesgll

---------KDKTVSLWSFVNSQ---IDVYKNPLYAElMNNKVLFPRTSIRILKLWTgYYM
         |  ..|.| ... |     .. | ||..  ...|| | ...  ||.|. ||.
yeekaekrakkagksvwdyidrqhkrspifynflysp.desevlrPssnvsslkvWd.yyl
subfamily_MTMR10_pd Subfamily MTMR10 242-603 5e-65 211.7 In-house 26-379 (380) alignment 
Range on Protein: 242-603
Range on HMM: 26-379/380.0
WRICHLNKNYELCDTYTSTFSVPLNCSDEMVQGVAQFRSKGRIPVLSWLHPVTQASItRCSQplVGTMNRRSKEDEQYMQEILKANDKSNklyildarpk
..    |.  . . |.   | ||  .||. |. . .   ..| |...| |. ..| . |.|.   .. .   ||.|. |.| ... . .|          
ivvllknelfaaaqtlPqyfvvpnslsdsdverlsrhykesRfplwvwshakgaall.rlsa..lqeaesadkekeekmlelvrkchpan..........

inamtnvamgggyehedcYVNMDFSFLDIGNIHVMRESLKKLREICYPDVD------DQRWFSNLESSHWLDHIKAILCGAVKVVECVETHKSSVVVHCT
                   |..     .. .|. . .. .||||.| .|        |..|.|.||...||. ....|  |...|..|...| ||..   
..................dvklvdlsdelpsiqdvqkaylklreLcvidtseefvtlddkwlssLektrWLayvrlclstasdavktvvekkrsvilqes

DGWDRTAQITSLSMLMMDSYFRTIKGFEVLVEKEWLGCGHKFSQRTGHGDKNHSDDQrsPIFLQFIDCVWQLMEQFPTAFEFNEHFLITILDHLYSCLFG
.| |    . ||. ||.|...|||.||. |..|||   ||.| .| ||.... . ..  |.|| | |||.||.||||..|||.|.|||...|. .|..|.
egrDlscvvaSLaqlmldphyrtisGfqsliqkewvaaghpfldrlghikpsekses..pvfllFldcvdqlleqfpseFeFtetfLialwdsshsgifl

TFLFNCERLRVEAGVKDKTVSLWSFVNSQIDV------YKNPLYAELMN-------------NKVLFPRTSIRILKLWTGYYMRWNP
|||||.|. |..| |. . . .  .   . |.      |...|||| ..              ... | ..|  ..||   |.|| |
tflfnseeqrlkavvsssplliakselkendllkdeldyrqglyaeiiksirrlaaaksylrseiirPllqipdiqlWdeCYlRWvP
subfamily_MTMR3_pd Subfamily MTMR3 227-328 6.9e-28 90.6 In-house 30-130 (442) alignment 
Range on Protein: 227-328
Range on HMM: 30-130/442.0
EAELKRMGVGNDGvPWRICHLNKNYELCDTYTSTFSVPLNCSDEMVQGVAQFRSKGRIPVLSWLHPVTQASITRCSQPLVGTMNRRSKEDEQYMQEILKA
..|..|.|   ..  ||| ..|....|| .| ... ||   .|.... ||.||| .|.|.. | |  ..| ..||||| || .  |..|||. ...| ||
keeverlGfdlke.awrisdvnsdfklCssyPkklivPksitdddlkkvasfrslkrlPavvwrhkkngavlarcsqPevgwlgWrnaedekllkaiaka

ND
  
ca
subfamily_pats1_pd Subfamily pats1 494-575 1.2e-24 78.7 In-house 553-634 (691) alignment 
Range on Protein: 494-575
Range on HMM: 553-634/691.0
SPIFLQFIDCVWQLMEQFPTAFEFNEHFLITILDHLYSCLFGTFLFNCERLRVEAGVKDKTVSLWSFVNSQIDVYKNPLYAE
||||.||.| ||||  .||. |||||..|...... .|  ||.||..  . ..|  |  .. |.|||.|     . | || .
sPifvqfldlvwqlqkefPfhfefneslllllvkesfssrfGnflyseakrdserkvlkrsksiwsfinqnksrfinllykh
subfamily_pats1_pd Subfamily pats1 363-488 1e-23 75.6 In-house 336-464 (691) alignment 
Range on Protein: 363-488
Range on HMM: 336-464/691.0
MDFSFLDIGNIHVMRESLKKLRE-ICYPDVDDQRWfSNLESSHWLDHIKAILCGAVKVVECVETHKSSVVVHCTDGWDRTAQI---TSLSMLMMDSYFRT
 .  ||..   . ..|   .| . |   |  |. | ...| |.|.| .| .| .||||   ..  .| ..   .|. . . ..   .||.....| ..||
sniiflslPtrekveerffdllqsilsldgsddew.keieeskwvdsvkllleaavkvsnlldeGssvllknsidsPlieldlasisslaqvlsdPfyrt

IKGFEVLVEKEWLGCGHKFSQRTGHGDKNH
. || ||.|||||  |. ||... | ....
ldGfkvliekewlsyGfPfskinyhkesdd
subfamily_MTMR5_pd Subfamily MTMR5 230-309 3.9e-15 47.6 In-house 14-98 (483) alignment 
Range on Protein: 230-309
Range on HMM: 14-98/483.0
LKRMGVG-----NDGVPWRICHLNKNYELCDTYTSTFSVPLNCSDEMVQGVAQFRSKGRIPVLSWLHPVTQASITRCSQPLVGTM
 ||.|.|     .  ...|| . ||.|..|..| . . || ..||. .. ||.   ..|.||  | |. ..| . | ...    .
ykRlGlgalngaskrgkfrisevNkkytvcrsYPalivvPsevsddsiarvakcfrqnRlPvvtWrhernkalLiRsggfeskgv
PTPc_DSPc_SM00012 417-526 5.7e-12 41.1 In-house 26-101 (105) alignment 
Range on Protein: 417-526
Range on HMM: 26-101/105.0
VKVVECVETH---KSSVVVHCTDGWDRTAQITSLSMLMMDSYFRTikgfevlvekewlgcghkfsqrtghgdknhsddqrspIFLQFIDCVWQLMEQFPT
.. |. ....   ...||||| .|..||.... |..|... . .|                                      .... ..|..|..| |.
lravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleket.....................................kevdifqivkelrkqRpg

AFEFNEHFLITIL
.....| .|. . 
mvqteeqylflyr
GRAM GRAM domain 104-150 2.3e-10 31.2 Pfam-A 25-68 (69) alignment 
Range on Protein: 104-150
Range on HMM: 25-68/69.0
HFLGSIEGTVYITSYKMYFKSDPNPKNTeesVVLNVPLGVISHVEKI
  .|  .|..|.|.|...|.||.. ...   ||. .||..|. |||.
tskgpvqGrlYlTnyrliFrSdklddsk...vvvvipladikrveks
subfamily_pats1_pd Subfamily pats1 219-306 2.8e-10 31.2 In-house 4-91 (691) alignment 
Range on Protein: 219-306
Range on HMM: 4-91/691.0
DGWEVYDPEAELKRMGVGNDgVPWRICHLNkNYELCDTYTSTFSVPLNCSDEMVQGVAQFRSKgRIPVLSWLHPVTQASITR---CSQPLV
. ...| .  | .|...  |   ||. ..  . .|.. |  .  ||   |||...  .. ||  .|||||| ..  ..|. |     ||. 
eifdiyslliegqrlkldld.kdwrvvefl.srdlseiyPkrilvPklvsdellvsyvrkrss.kiPvlswsnqnnksslfricvynqpfn
0045098 (Phosphotyrosine protein) phosphatases II 366-467 5.5e-09 31.3 In-house 137-257 (278) alignment 
Range on Protein: 366-467
Range on HMM: 137-257/278.0
SFLDIGNIHVMRESL--KKLREICYPDVDDQRWFSNLESSHWLDHIKAILCGAVKVVECVET------HKSSVVVHCTDGWDRTAQITSLSMLMMD----
 .| . |..|.||.|   ... ..|. ..|  . |.  ....|.... |.    .... ...      ..  |.|||  |..||. .  . ...      
rtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvlVHCsaGvgRtGtlvaaylmlellegg

-------SYFRTIKGFEVLVE
       ...|. ......  
vdlleavkelrsqRpglavqn
0049772 (Phosphotyrosine protein) phosphatases II 353-452 1.8e-08 30.0 In-house 155-237 (314) alignment 
Range on Protein: 353-452
Range on HMM: 155-237/314.0
GyehedcyvnmdfSFLDIGNI---HvmreslkklrEICYPDVDDQRWFSNLESSHWLDHIKAILCGAVKVVECVET--HKSSVVVHCTDGWDRTAQITSL
|            ....  ..   .          |..|.. . .|.  ..   .. |.   .|    ...| .|.   .. |.|||..|..||.    .
g............neptaadlellk..........eelydpelferlgikylripvpDgsaplledfdeflefieeadkggpvlvHCkaGkgRtgtfvva

SMLMM
 .||.
aylmk
0051429 (Phosphotyrosine protein) phosphatases II 382-453 1e-06 24.1 In-house 104-176 (272) alignment 
Range on Protein: 382-453
Range on HMM: 104-176/272.0
KLREICYP---DVDDQRWFSNLESSHWLDHIKAILCgAVKVVECVEThKSSVVVHCTDGWDRTAQITSLSMLMMD
 |||...    . .. |..  |    |.||  .     ....| . . .  |.|||. |.|||. .  | .|...
ilrellltlllsagearevmhlhytdwpdhgvpqea.llellellld.ggpvlvHCsaGkdRTGtvvallllllg
DSPc Dual specificity phosphatase, catalytic domain 380-447 4.5e-06 21.6 Pfam-A 37-93 (133) alignment 
Range on Protein: 380-447
Range on HMM: 37-93/133.0
LKKLREICYPdVDDqrwfsnlessHWLDHIKAILCGAVKVVECVETHKSSVVVHCTDGWDRTAQITSL
 .. .....| |.|          .. . | . |  ||...| .|. . .|.|||. |  |.| ..  
kseieylrip.ved..........etetkiskeleeavefiekaeqkgkkvlVHCqaGisRSatliia
DSPc Dual specificity phosphatase, catalytic domain 380-447 4.5e-06 21.6 In-house 37-93 (133) alignment 
Range on Protein: 380-447
Range on HMM: 37-93/133.0
LKKLREICYPdVDDqrwfsnlessHWLDHIKAILCGAVKVVECVETHKSSVVVHCTDGWDRTAQITSL
 .. .....| |.|          .. . | . |  ||...| .|. . .|.|||. |  |.| ..  
kseieylrip.ved..........etetkiskeleeavefiekaeqkgkkvlVHCqaGisRSatliia
3-PAP Myotubularin-associated protein 578-638 4.5e-06 17.0 Pfam-A 73-133 (142) alignment 
Range on Protein: 578-638
Range on HMM: 73-133/142.0
NNKVLFPRTSIRILKLWTGYYMRWNPRMK------PQESEFERSRQLQIlikllkEKCQELTEQQRN
.. .| |..... |.||. .|.|| |  .      .|.... .  . .|      .| |.| ||...
lhqlLlpqqlgldlslWsqcylRwiPeaeikgggqvqvdlklselleei......aklqrlleqrdm
0044763 (Phosphotyrosine protein) phosphatases II 408-450 7.6e-06 21.2 In-house 90-133 (178) alignment 
Range on Protein: 408-450
Range on HMM: 90-133/178.0
HIKAILCGAVKVVECVE-THKSSVVVHCTDGWDRTAQITSLSML
 . ...  .|. .| .  .... |.|||. |..|.. .  . ..
dllehflefvefieealdekggpvlVHCsaGvgRsgtlvaaylm