Gene MTMR3 in Amphimedon queenslandica

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family Myotubularin
Subfamily MTMR3
Protein sequence
ID Type Fasta BLAST phosphatome Note
AqueP030_AA protein Get Run
AqueP030_AA_156-556 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_MTMR3_pd Subfamily MTMR3 146-550 2e-193 636.2 In-house 12-441 (442) alignment 
Range on Protein: 146-550
Range on HMM: 12-441/442.0
KKRQLKRRGNPSLSTELLTSEYSRLGFNKPGTWRITDANAKYELCSSYPKVFVVPQSVTDSDLLQVSKFRSLSRLPAVVWRHKGNGCVLARASQPLVGFL
|.|.     ..| ..| |..|..||||.. ..|||.|.|....||||||| ..||.|.||.|| .|..||||.||||||||||.||.||||.||| ||.|
kerdgfllraasvaeeklkeeverlGfdlkeawrisdvnsdfklCssyPkklivPksitdddlkkvasfrslkrlPavvwrhkkngavlarcsqPevgwl

GWRCQEDEQFLKALSKSCHPHAPPmevMSHGEKITNGVG-----------------------QTPSLLVVDLRSYTAAFGNRAKGGGCEHQDYYSNCEIV
|||..|||..|||..|.|. .|..   ...|||..||.                        .. .||.||.|||||||.|||||||||...||.|||.|
gWrnaedekllkaiakacaldage...kakgeklsngkakkkdvsdaldaeadaseeeslaeekkkllivdarsytaafanrakgGGceleeyypncevv

YKGLPNIHSVRTSFGSLRNLLS-GNEQIRFFSQLEGTHWLQNISQLLQTAVEVSNTLHHHSRPVLIHCSDGWDRTTQITSLAQLLLDPYYRSLEGFRVLV
..||.|||.||.|| |||.||| ........|.|| |.||||.|.||..||.|........||||.||||||||||||..||.||||||||.||||.|||
flglanihavrksfnslrallsqspdesnwlsalektkWlqnlsvllkaavkvveavdkegrpvlvhCsdGWdrttqivalakllldpyyrtleGfkvlv

EREWLSFGHKFSDRCGFGPD----GEQSPVFLQWLDCLYQISNQFPTSFEFNSIFLVKLAQHCYSQLYGTFLGNCEQERERELVRLQTLSLWDCL-EKER
|||||.|||||.||||.|..    .|..||||||||...|...|||||||||..|||||.||.||.|.||||.|.|.|||.| |. .|||.|..| .||.
ereWldfGhkfadrcghgenvddanercPvflqwldavhqlqrqfPtsfefneaflvklvqhtysclfGtflansekereeekvkertlsvWsllrakek

EITNAIYKENgDEVVLCPNYQVRSLKLWRELFLH
|..|..|||. .|.||.|...||.||||.|..|.
eyrnllykek.teavllpavsvrelklwsevyle
0040695 (Phosphotyrosine protein) phosphatases II 160-550 4.7e-130 427.6 In-house 10-384 (388) alignment 
Range on Protein: 160-550
Range on HMM: 10-384/388.0
TELLTSEYSRLGFNKPgTWRITDANAKYELCSSYPKVFVVPQSVTDSDLLQVSKFRSLSRLPAVVWRHKGNGCVLARASQPLVGFLGWRCQEDEQFLKAL
.   . |..|||..   .|||.. | .||||.||| ..|||.|..|..| .|..|||  |.|....||. ||.|| | ||||||.|..|..|||..|.|.
lydilrelkrlglgld.lwrisivNenyelcpsYPallvVPksisdellkrvarfrskgriPvlsyrhpnngavllRssqplvglllsrsledeklleai

SKSCHphappmevmshgekitngvgQTPSLLVVDLRSYTAAFGNRAKGGGCEHQDYYSNCEIVYKGLPNIHSVRTSFGSLRNLLSGNE-QIRFFSQLEGT
 |...                    ... ||.||||... |. |||.|||.| .|.|.|.|......|||| || |. .|.... ...   ...| || .
lkllp....................nlskllivdlrpklnalanralgggvenedaypnaeliflnipnihvvreslqklldaclnvpdslnllsllees

HWLQNISQLLQTAVEVSNTLHHHSRPVLIHCSDGWDRTTQITSLAQLLLDPYYRSLEGFRVLVEREWLSFGHKFSDRCGFGPD----GEQSPVFLQWLDC
.||. |...|..||.. . |.. . .||.|||||||||.|..||||||||||||.||||.||.|.|||||||||.||.|....     | |||||..|||
gwldliklilelavlivklldlgnssvlvhcsdgwdrtsqlssLaqllldPyYRTleGFqvLiekeWlsfghkfadRlghleseidskefsPvFllFLdc

LYQISNQFPTSFEFNSIFLVKLAQHCYSQLYGTFLGNCEQERERELVRLQTLSLWDCLE-KEREITNAIYKENGDEvVLCPNYQVRSLKLWRELFLH
..|. .||||.||||. .|. ||.|.|| ..||||.|.|.|| .  |. .|||||..|   ..| .| .|. . .| || |...|..|.|| |..|.
vwqLlrqfPtaFeFnerlLlfLadhlyscrfgtFlfnsekerlelsvsertlslwsyllsrkseflnplYdpssle.vllpslsvldlllWleyylr
Myotub-related Myotubularin-like phosphatase domain 147-498 2.8e-129 423.9 Pfam-A 11-352 (353) alignment
Myotub-related Myotubularin-like phosphatase domain 147-498 2.8e-129 423.9 In-house 11-352 (353) alignment
subfamily_MTMR1_pd Subfamily MTMR1 165-549 2.6e-127 417.4 In-house 14-384 (389) alignment 
Range on Protein: 165-549
Range on HMM: 14-384/389.0
SEYSRLGFNKPGTWRITDANAKYELCSSYPKVFVVPQSVTDSDLLQVSKFRSLSRLPAVVWRHKGNGCVLARASQPLVGFLGWRCQEDEQFLKALSKSch
.|. |||  .  .||||. | ||||| .||.|.|||..|.|.|| .|..||| .||| ..| .| |..|..||||||||  | |..|||..|.|. ..  
aelerlgllneklWritklnkkyelcdtYpavlvvpkvvsdedlkkvaafrskgRlPvlswlnkenqavilrasqplvGlsgkrskedekylqailea..

phappmevMShgekitngvgQTPSLLVVDLRSYTAAFGNRAKGGGCEHQDYYSNCEIVYKGLPNIHSVRTSFGSLRNLLS-GNEQIRFFSQLEGTHWLQN
         .          |.  ||..| || ..|..|.|||.| |....| |.|...  ..|||.|| |.  |..|.    .. ...|.||.|.||..
........na..........qsekllildarssvnavankakgkgyeseeaYknaelifldihnihvvReslkklkelvlpnvddkkwlsalestkWleh

ISQLLQTAVEVSNTLHHHSRPVLIHCSDGWDRTTQITSLAQLLLDPYYRSLEGFRVLVEREWLSFGHKFSDRCGFGP----DGEQSPVFLQWLDCLYQIS
|...|..||.. .......  ||.|||||||||.|.||||.||||.|||..|||.||.|.|||||||||..| | |     | |.||||||..||..|..
iklilagavkivekvetektsvlvhcsdGWDRtaqltsLamlllDsyyRtieGfevliekeWlsfGHkfkeRlghgdknssdaersPvFlqfiDcvwqlt

NQFPTSFEFNSIFLVKLAQHCYSQLYGTFLGNCEQERERELVRLQTLSLWDCLEKER-EITNAIYKENGDEVVLCPNYQVRSLKLWRELFL
.|||| ||||. ||. |..| ||.|.|||| |.|.||..| |  .|.|||  ..... | || .|.|. .. || |. ..|.|.||.| .|
rqfptAFefneefLitlldhlysclfGtflfnsekervkekvkektvslwsyvnsskeeftnplyaeelekkvlypkaslrrlelWkeyyl
subfamily_Dicty-MTMR1-like_pd Subfamily Dicty-MTMR1-like 165-550 6.1e-123 402.9 In-house 23-401 (404) alignment 
Range on Protein: 165-550
Range on HMM: 23-401/404.0
SEYSRLGFNKPGTWRITDANAKYELCSSYPKVFVVPQSVTDSDLLQVSKFRSLSRLPAVVWRHKGNGCVLARASQPLVGFLGWRCQEDEQFLKALSKSCH
.||.|||...   |||...| .||||..|||..|||.|..|..| .|..|||  |.|...|||. ......|.||||||  . |..|||.......|.. 
eEykRlgikseseWriskinsdyelcetYPkllvvPesisDeelkkvasfRskgRiPvlswrhrsknstitRssqplvGltksrseedEklinsirkakt

PHAppmevmshgekitngvgqtpSLLVVDLRSYTAAFGNRAKGGGCEHQDYYSNCEIVYKGLPNIHSVRTSFGSLRNLLSGNEQ--IRFFSQLEGTHWLQ
                       .|...| |... |  |.||| |.|. . |.||||  ... |||..| |. .|... . ...    ..|.|| ..||.
qle....................tlyildarpkanavansakgagyedisryenceieflnienihelreslkklkkavnsiiekeknwlselessrWld

NISQLLQTAVEVSNTLHHHSRPVLIHCSDGWDRTTQITSLAQLLLDPYYRSLEGFRVLVEREWLSFGHKFSDRCGF---GPDGEQSPVFLQWLDCLYQIS
.|..||... .......... .||.|||||||||.|..||.||||||||| .||| ||.|.||||||||| .|.|      . |.||.|||..|| ||. 
hiklllegskriveliekekssvlvhcsdgwDrtsqlsslsqllldpyyrtiegFivliekewlsfGhkfaqRigqttekssdersPiflqFidcvyqlt

NQFPTSFEFNSIFLVKLAQHCYSQLYGTFLGNCEQERERELVRLQTLSLWDCLEKER-EITNAIYK--ENGD-EVVLCP----NYQVRSLKLWRELFLH
.|||||||||. ||.|. .. ||  .|||| ..|.||... .  .| |||  ||... |  | .|   ..   | .       . ... .|||.|..|.
kqfptsFeFnekflikildalyscrfgtFLydsekeRqqnnlaketvslWalleankseylnplyilekkeqkenitssessssadikliklWseyylr
subfamily_MTMR6_pd Subfamily MTMR6 163-549 1.6e-107 352.2 In-house 24-393 (397) alignment 
Range on Protein: 163-549
Range on HMM: 24-393/397.0
LTSEYSRLGFNKPgTWRITDANAKYELCSSYPKVFVVPQSVTDSDLLQVSKFRSLSRLPAVVWRHKGNGCVLARASQPLVGFLGwRCQEDEQFLKALSKS
|..||.|.|  .  .| .||.| .||||..||. ..||.|.| . |.  |||||  ||| . . || |   . |.|||| ||   ||.|||..|.|..|.
lkaeytrmgvpne.kwtltdlnkdyelcdtyprelyvPksatkevlvgsskfrskgrlPvlsylhkeneaaicrcsqplsgfsa.rcledeklleairka

chphappmevmshgekitNGvgQTPSLLVVDLRSYTAAFGNRAKGGGCEHQDYYSNCEIVYKGLPNIHSVRTSFGSLRNLL--SGNEQIRFFSQLEGTHW
                  |   .. .| ||| |    |. |.|.| | |..| |||... . |. ||| .|.|   | .    . . .  |.| || . |
..................np..nsellyvvdtrpklnalankaagkGyenednysnikfqfvgienihvmreslqkllevvelksksvseflsglessgw

LQNISQLLQTAVEVSNTLHHHSRPVLIHCSDGWDRTTQITSLAQLLLDPYYRSLEGFRVLVEREWLSFGHKFSDRCGF--GPDGEQSPVFLQWLDCLYQI
|. | ..|.... ........   ||.|||||||||.|..|||.||||||||...|| ||.|.||||||||||.|||.  .   | ||.|.|.|.|..|.
lkhikavldasifiakavaeegasvlvhcsdGwdrtaqvcslasllldpyyrtikGflvliekewlsfGhkfsercGlldedskevsPiftqflecvwql

SNQFPTSFEFNSIFLVKLAQHCYSQLYGTFLGNCEQERERELVRLQTLSLWDCLEK-EREITNAIYKENGDEVVLCPNYQVRSLKLWRELFL
 .|||..||||  ||..| .| ||  .||||||||..|.   .. .| |||  | . . . .| .||.. .. || |. .. .||||| |. 
leqfpkafefnerfllelhdhvyscqfGtflgncekdrrdlklkertkslwayllerkddylnplykaetekevlkpdtapaalklwralyn
subfamily_Ank-MTMR1_pd Subfamily Ank-MTMR1 176-549 4e-83 271.4 In-house 40-402 (405) alignment 
Range on Protein: 176-549
Range on HMM: 40-402/405.0
GTWRITDANAKYELCSSYPKVFVVPQSVTDSDLLQVSKFRSLSRLPAVVWRHKGNGCVLARASQPLVGFLGWRCQEDEQFLKALSKSChphaPpmevmsh
  |..|. | .|..||||.  .|| .  .| || ..  |||  |.|.. |.     . ..|.||||||    || ||| .  .|. |.    |       
cywkvtsinkeykmcssyssslvvlskaldkdlekifsfrskgripslswkdpssnasisrcsqplvgierarcpedelycsslalsa....p.......

gEKitngvgqtpSLLVVDLRSYTAAFGNRAKGGGCEHQDYYSNCEIVYKGLPNIHSVRTSFGSLRNLLS---------GNEQIRFFSQLEGTHWLQNISQ
  |         .| ..| |    |. | |.| | |    | || .|.  .|||| .| |.  |   .             ..||.  .| | |.  |  
.sk.........tlylidarpklnaiantangagfenihnypncklvfmnipnihvirksleklvlamkssardkdhtestdmrfwgyieetgwishiks

LLQTAVeVSNTLHHHSRPVLIHCSDGWDRTTQITSLAQLLLDPYYRSLEGFRVLVEREWLSFGHKFSDRCGFGP--DGEQSPVFLQWLDCLYQISNQFPT
.|..|  .|  |  .   .|.||||||||| |||||.|.|||||||.. ||.||.|.|||||||||| | |  |  . |.||.| |.||| .|. .||| 
ileaat.fsaelilkgnsilvhcsdgwdrtpqitsltqilldpyyrtivgfqvliekewlsfghkfslrlghlpgneeerspifqqfldccfqllsqfpl

SFEFNSIFLVKLAQHCYSQLYGTFLGNCEQERERELVRLQTLSLWDCLEKEREITNAIYKENGDEVVLCPNYQVRSLKLWRELFL
 |||   .|. ...  .|  ||||| |||..| .. |...|.|.|  .. . .     | .  |   . |.   | |.||.  ..
lfeftpslllfisdnihsckygtflnncekdrvqdqvktktisiwsevnlnvnkflnpyynpqdiqsikpklysrclelwkacym
subfamily_MTMR9_pd Subfamily MTMR9 290-550 2.6e-69 226.2 In-house 123-391 (393) alignment 
Range on Protein: 290-550
Range on HMM: 123-391/393.0
LVVDLRSYTAAFGNRAKGGGCEHQDYYSNCEIVYKGLPNIHSVRTSFGSL--RNLLSGNEQIRFFSQLEGTHWLQNISQLLQTAVEVSNTLHHHSRPVLI
|.|| || .||  .|.|||| | .. ||. . ... | ...|.  |.  |       | .. .|.|.|| . ||... .||..|. |...|...  ||..
livdtrsksaaenarskgggietevkysqwkkasrslesvasiqdslaklleacsdaglstdkflsrleksgwlsqvadlleaalvvaqcldeegapvvv

HCSDGWDRTTQITSLAQLLLDPYYRSLEGFRVLVEREWLSFGHKFSDRCG---FGP--DGEQSPVFLQWLDCLYQISNQFPTSFEFNSIFLVKLAQHCYS
| ..| | | |.||||||.|||..| ..||  |.||||.  || |. |.    . .  . ...|||| .|||.||| .||| |||||  .|. | .| ||
hgeeGlDatlqvtsLaqlildpdaRtvrgfealiereWiqaGHPFasRaskvaaketkkklsgpvfllFLDcvyqilsqfpasFEFneelLillfehsys

QLYGTFLGNCEQERERELVRLQTLSLWDCLEKE---REITNAIYKEngDEVVLCPNYQVRSLKLWRELFLH
  .||||...|.||... .. .| |||. ....   ....| .|..  .. |..|. .  ||.||.||.|.
sqfgtflcdneaerkelklkkktvslwsyvnrpeklkqflnplyea..naeviwpsvapqslelWselylr
subfamily_MTMR5_pd Subfamily MTMR5 312-545 9.5e-65 211.2 In-house 221-476 (483) alignment 
Range on Protein: 312-545
Range on HMM: 221-476/483.0
HQDYYSNCEIVYKGLPNIHSVRTSFGSLRNLLSGN------EQIRFFSQLEGTHWLQNISQLLQTAVEVSNTLHHHSRPVLIHCSDGWDRTTQITSLAQL
... .|..|..   |..|  |..||  |.   . .      |.  | ...|   ||| ||.||| .. |.. |  .   ||.   |||| |.|..|||||
ksevdskaefipvelveirqvkasfkkllraClpstaveeaesqsFlksvedseWlqqissllqlsgavvdlldlqgssvlvslEdGwdvtaqvsslaql

LLDPYYRSLEGFRVLVEREWLSFGHKFSDRCGFGPDGEQ---SPVFLQWLDCLYQISNQFPTSFEFNSIFLVKLAQHCYSQLYGTFLGNCEQERERELV-
|||||||.||||.||||.|||.|||.|..|.   .  ..   .|||||.||| .|.|.|||..||||. .|  || |  |. . ||| ..|.||  . . 
lldpyYRtleGFkvLveKEWLafGHrFtkrsnqtlsaqssgfaPvFlqFLDcvhqvsrqfPlafefndfylkflayhsvsnrfrtfllDseyerlesgll

-------RLQ--TLSLWDCLEKEREITNAIYKE---NGDEVVLCPNYQVRSLKLWR
       | .  . |.||..... . . . | .   . ...|| |. .| |||.| 
yeekaekrakkagksvwdyidrqhkrspifynflyspdesevlrPssnvsslkvWd
subfamily_MTMR10_pd Subfamily MTMR10 324-511 2.9e-47 153.2 In-house 121-317 (380) alignment 
Range on Protein: 324-511
Range on HMM: 121-317/380.0
KGLPNIHSVRTSFGSLRNLLSGNE-------QIRFFSQLEGTHWLQNISQLLQTAVEVSNTLHHHSRPVLIHCSDGWDRTTQITSLAQLLLDPYYRSLEG
. ||.|. | ...  ||.|   .        . ...|.|| |.||. .. .|.||.....|.... |.|..  |.| |    . |||||.|||.||...|
delpsiqdvqkaylklreLcvidtseefvtlddkwlssLektrWLayvrlclstasdavktvvekkrsvilqesegrDlscvvaSLaqlmldphyrtisG

FRVLVEREWLSFGHKFSDRCGFGPDGEQ--SPVFLQWLDCLYQISNQFPTSFEFNSIFLVKLAQHCYSQLYGTFLGNCEQERERELVRLQTLSLWDC
|  |...|| . ||.| ||.| . . |.  |||||  ||| .|  .|||..|||.  ||..|  ...| ...||| |.|..|... |  . | .   
fqsliqkewvaaghpfldrlghikpseksespvfllFldcvdqlleqfpseFeFtetfLialwdsshsgifltflfnseeqrlkavvsssplliaks
subfamily_pats1_pd Subfamily pats1 317-436 1.3e-24 78.6 In-house 334-457 (691) alignment 
Range on Protein: 317-436
Range on HMM: 334-457/691.0
SNCEIVYKGLPNIHSVRTSFGSLRN-LLSGNEQIRFFSQLEGTHWLQNISQLLQTAVEVSNTLHHHSRPVLIHCSDGWDRTTQI---TSLAQLLLDPYYR
  ..|..  ||  . |.  |  | . .|| ..    ....|  .|. ..  ||..||.||| | . |  .|   .|. . . ..   .||||.|.||.||
issniiflslPtrekveerffdllqsilsldgsddewkeieeskwvdsvkllleaavkvsnlldeGssvllknsidsPlieldlasisslaqvlsdPfyr

SLEGFRVLVEREWLSFGHKFSDRC
.|.||.||.|.||||.|. ||...
tldGfkvliekewlsyGfPfskin
subfamily_MTMR9_pd Subfamily MTMR9 175-259 6.3e-24 76.8 In-house 31-115 (393) alignment 
Range on Protein: 175-259
Range on HMM: 31-115/393.0
PGTWRITDANAKYELCSSYPKVFVVPQSVTDSDLLQVSKFRSLSRLPAVVWRHKGNGCVLARASQPLVGFLGWRCQEDEQFLKAL
   |||.. | ....|.|||. ..||....| .| ....||. .|.|   ..|| .. || |.||||.|  | ||.|||..|.. 
sdewRissvNknfkvcasypesvivPkaiddeelkasaafreggrfPvLsylhketkavllrssqplcgssgkrckedekllnlv
subfamily_MTMR5_pd Subfamily MTMR5 164-240 3.5e-23 74.1 In-house 11-93 (483) alignment 
Range on Protein: 164-240
Range on HMM: 11-93/483.0
TSEYSRLGFN------KPGTWRITDANAKYELCSSYPKVFVVPQSVTDSDLLQVSKFRSLSRLPAVVWRHKGNGCVLARASQP
  .|.|||..      | |..||. .| ||..| ||| ..|||..| |. . .|.|     |||.|.|||. |. .| |....
vqdykRlGlgalngaskrgkfrisevNkkytvcrsYPalivvPsevsddsiarvakcfrqnRlPvvtWrhernkalLiRsggf
FYVE FYVE zinc finger 852-914 3.6e-19 58.5 Pfam-A 2-67 (69) alignment 
Range on Protein: 852-914
Range on HMM: 2-67/69.0
TWIPDHAVSHCP-CGAEFWMGKRKHHCRSCGGIFCWQCSNYFTPVP--HEQLFKDQRVCKICFDKL
.| .|.....|. |...| . .|.|||| || ..| .||. .....  ...  |..|||| |...|
kwvddaeakkCeiCakkFsltrrrhhCrlCGkvvCskCsskrvekleeesaeekevrvCkeCleel
subfamily_pats1_pd Subfamily pats1 445-526 2.2e-15 48.1 In-house 553-635 (691) alignment 
Range on Protein: 445-526
Range on HMM: 553-635/691.0
SPVFLQWLDCLYQISNQFPTSFEFNSIFLVKLAQHCYSQLYGTFLGNCEQERERELVRLQTLSLWDCLEKER-EITNAIYKEN
||.|.|.|| ..|.  .||. ||||  .|. | .. .|  .|.|| .  ...  . |  .. |.|   ....   .| .||. 
sPifvqfldlvwqlqkefPfhfefneslllllvkesfssrfGnflyseakrdserkvlkrsksiwsfinqnksrfinllykhs
PTPc_DSPc_SM00012 366-474 1.1e-09 33.8 In-house 21-98 (105) alignment 
Range on Protein: 366-474
Range on HMM: 21-98/105.0
QLLQTAVEVSNTLHHH--SRPVLIHCSDGWDRTTQITSLAQLLLDPYYRSlegfrvlverewlsfghkfsdrcgfgpdgeqspVFLQWLDCLYQISNQFP
 .|..  .| .  ...  | ||..|||.|..|| ... |. || . ....                                  ........ .. .| |
silellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleket.................................kevdifqivkelrkqRp

TSFEFNSIFLV
......  .|.
gmvqteeqylf
subfamily_pats1_pd Subfamily pats1 165-236 1.2e-08 25.8 In-house 13-82 (691) alignment 
Range on Protein: 165-236
Range on HMM: 13-82/691.0
SEYSRLGFNKPGTWRITDANaKYELCSSYPKVFVVPQSVTDsDLLQVSKFRSLSRLPAVVWRHKGNGCVLAR
 |. ||. .    ||...   . .|.  |||  .||..|.| .||. .  .  |..| . | .. |  .| |
iegqrlkldldkdwrvvefl.srdlseiyPkrilvPklvsd.ellvsyvrkrsskiPvlswsnqnnksslfr
subfamily_MTMR10_pd Subfamily MTMR10 177-238 5.3e-08 24.0 In-house 25-85 (380) alignment 
Range on Protein: 177-238
Range on HMM: 25-85/380.0
TWRITDANAKYELCSSYPKVFVVPQSVTDSDLLQVSKFRSLSRLPAVVWRHkGNGCVLARAS
... .  | . . . ..|. ||||.|..|||. ..|.    || |  || | ..| .| | |
aivvllknelfaaaqtlPqyfvvpnslsdsdverlsrhykesRfplwvwsh.akgaallrls
subfamily_MTMR14_pd Subfamily MTMR14 382-438 6.9e-07 20.4 In-house 268-330 (357) alignment 
Range on Protein: 382-438
Range on HMM: 268-330/357.0
SRPVLIHCSDGWDRTTQITSLAQLLL--D-PYYRSLEGFRVL---VEREWLSFGHKFSDRCGF
   .|.||  |||||   .|| .| |  |   ..||.  ..|   |  .|. |||...||   
dsGllvhcisGWdrtPlfvsllrlslWadglihqslsaaellyltvaydWflfghqlpdrlkk
0051429 (Phosphotyrosine protein) phosphatases II 345-408 2.3e-06 23.0 In-house 115-176 (272) alignment 
Range on Protein: 345-408
Range on HMM: 115-176/272.0
GNEQIRFFSQLEGTHWLQNISQL--LQTAVEVSNTlhhhSRPVLIHCSDGWDRTTQITSLAQLLLD
.....| . .|  | |.        | ...|. ..    ..|||.||| |.|||  .  |  |||.
sagearevmhlhytdwpdhgvpqeallellellld....ggpvlvHCsaGkdRTGtvvallllllg
0049772 (Phosphotyrosine protein) phosphatases II 362-402 2.3e-06 23.1 In-house 193-232 (314) alignment 
Range on Protein: 362-402
Range on HMM: 193-232/314.0
QNISQLLQTAVEVSNTLhHHSRPVLIHCSDGWDRTTQITSL
..... .. ..|. ... .  .|||.||..|..||.    .
aplledfdeflefieea.dkggpvlvHCkaGkgRtgtfvva
0044763 (Phosphotyrosine protein) phosphatases II 359-400 2.7e-06 22.6 In-house 86-128 (178) alignment 
Range on Protein: 359-400
Range on HMM: 86-128/178.0
HWLQNISQLLQTAVEVSNTLH-HHSRPVLIHCSDGWDRTTQIT
|  ..... .. .||  ....  . .|||.||| |..|.. . 
hgvpdllehflefvefieealdekggpvlVHCsaGvgRsgtlv
0048076 (Phosphotyrosine protein) phosphatases II 359-401 2.9e-06 22.6 In-house 58-100 (145) alignment 
Range on Protein: 359-401
Range on HMM: 58-100/145.0
HWLQNISQLLQTAVEVSNTLHHHSRPVLIHCSDGWDRTTQITS
|  .....||....|  .... . .|||.||| | .||. .  
hgvpdllellleflefieealkeggpvlVHCsaGvgRtgtlva
0048179 (Phosphotyrosine protein) phosphatases II 358-401 3e-06 22.6 In-house 59-102 (144) alignment 
Range on Protein: 358-401
Range on HMM: 59-102/144.0
THWLQNISQLLQTAVEVSNTLHHHSRPVLIHCSDGWDRTTQITS
 |   ....||....|  .... ...|||.||| | .||. .  
DhgvpdllellleflefieealeeggpvlVHCsaGvgRtgtlva
0051082 (Phosphotyrosine protein) phosphatases II 359-406 6.7e-06 21.3 In-house 68-116 (151) alignment 
Range on Protein: 359-406
Range on HMM: 68-116/151.0
HWLQNISQLLQTAVEVSNTLHHH-SRPVLIHCSDGWDRTTQITSLAQLL
.. ...........|. . | .. . |||.||| |..||  .  |  .|
wpdpglplsfdavleflellldkkngpvlvHCsaGkgRTGtlvalylml