Gene MTMR6 in Amphimedon queenslandica

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family Myotubularin
Subfamily MTMR6
Protein sequence
ID Type Fasta BLAST phosphatome Note
AqueP033_AA protein Get Run
AqueP033_AA_124-504 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_MTMR6_pd Subfamily MTMR6 108-502 5.4e-205 673.2 In-house 1-396 (397) alignment 
Range on Protein: 108-502
Range on HMM: 1-396/397.0
LYAFQFTPSSDGFVKSSGWNLYDSVVEYGRMGVPNEHWVCTELNKDYELCETYSNTLFVPAKAEKSVVLGSAKFRSKGRLPVLSYYCQAKNSALCRSSQP
||||...|..| ..|.|||.|.|. .||.|||||||.|..|.||||||||.||...|.||..|.|.|..||.|||||||||||||.......|.||.|||
lyafsykpkkdkeekvsGwklldlkaeytrmgvpnekwtltdlnkdyelcdtyprelyvPksatkevlvgsskfrskgrlPvlsylhkeneaaicrcsqp

LTYITRRSQEDEAMIQAIIDANPNSSSLHLLDSRPKINAVANKAAHKgGYETTDNYPNIVYQFNNIQNIHVMRESLQKLLEAL-HSPAGVSSVLQGLDAS
|.....|..|||....|| .|||||..|...|.|||.||.|||||.| |||..||| || .||..|.||||||||||||||.  ..   ||..|.||..|
lsgfsarcledeklleairkanpnsellyvvdtrpklnalankaagk.Gyenednysnikfqfvgienihvmreslqkllevvelksksvseflsgless

SWLRHIHLVLEAGAFIAKALYTEGINVLVHCSDGWDRTAQTCSLASLMIDKYYRTIHGFMILIEKEWLSFGHKFTIRSGHINSDSKEVSPIFTQFLDAVW
.||.||. ||.|..|||||...||..||||||||||||||.||||||..|.|||||.||..|||||||||||||. |.|....|||||||||||||..||
gwlkhikavldasifiakavaeegasvlvhcsdGwdrtaqvcslasllldpyyrtikGflvliekewlsfGhkfsercGlldedskevsPiftqflecvw

QIMVQFPKSFEFNELFLLTIHDHLFSCQFGTFLGNNERDRKINKFSEKTYSLWGYIWSRLDDFTNPLFDNDTE-NYIMPKTEVSILSLWRGLYCCYE
|.. ||||.||||| |||..|||..||||||||||.|.||. .|..|.|.|||.|...| ||..|||....|| ....|.|... |.|||.||....
qlleqfpkafefnerfllelhdhvyscqfGtflgncekdrrdlklkertkslwayllerkddylnplykaetekevlkpdtapaalklwralynrfd
subfamily_MTMR1_pd Subfamily MTMR1 122-502 1.1e-140 461.4 In-house 3-387 (389) alignment 
Range on Protein: 122-502
Range on HMM: 3-387/389.0
KSSGWNLYDSVVEYGRMGVPNE-HWVCTELNKDYELCETYSNTLFVPAKAEKSVVLGSAKFRSKGRLPVLSYYCQAKNSALCRSSQPLTYIT-RRSQEDE
|. ||..|| . |. |.|..|| .|  |.|||.||||.||...|.||. .. ... ..|.|||||||||||.. . ..... |.||||. .. .||.|||
kedGWkvydpeaelerlgllneklWritklnkkyelcdtYpavlvvpkvvsdedlkkvaafrskgRlPvlswlnkenqavilrasqplvGlsgkrskede

AMIQAIIDANPNSSSLHLLDSRPKINAVANKAAhKGGYETTDNYPNIVYQFNNIQNIHVMRESLQKLLEALHSPAGVSSVLQGLDASSWLRHIHLVLEAG
...|||..|| .|. | .|| |...|||||||   .|||....| |.   | .|.||||.||||.|| |.. .    .. |. |... || ||.|.|.. 
kylqaileanaqsekllildarssvnavankak.gkgyeseeaYknaelifldihnihvvReslkklkelvlpnvddkkwlsalestkWlehiklilaga

AFIAKALYTEGINVLVHCSDGWDRTAQTCSLASLMIDKYYRTIHGFMILIEKEWLSFGHKFTIRSGH--INSDSKEVSPIFTQFLDAVWQIMVQFPKSFE
  |.... || ..||||||||||||||  ||| |..| |||||.|| .|||||||||||||. | ||   ||  .| ||.| ||.|.|||.. |||  ||
vkivekvetektsvlvhcsdGWDRtaqltsLamlllDsyyRtieGfevliekeWlsfGHkfkeRlghgdknssdaersPvFlqfiDcvwqltrqfptAFe

FNELFLLTIHDHLFSCQFGTFLGNNERDRKINKFSEKTYSLWGYIWSRLDDFTNPLFDND-TENYIMPKTEVSILSLWRGLYCCYE
||| ||.|. ||| || ||||| |.|. |. .| .||| ||| |. |. ..|||||.... ... ..||. .. | ||.  |. ..
fneefLitlldhlysclfGtflfnsekervkekvkektvslwsyvnsskeeftnplyaeelekkvlypkaslrrlelWkeyylrwn
0040695 (Phosphotyrosine protein) phosphatases II 123-499 6.8e-136 446.8 In-house 5-383 (388) alignment 
Range on Protein: 123-499
Range on HMM: 5-383/388.0
SSGWNLYDSVVEYGRMGVPNEHWVCTELNKDYELCETYSNTLFVPAKAEKSVVLGSAKFRSKGRLPVLSYYCQAKNSALCRSSQPLTYIT-RRSQEDEAM
  ||.||| . |. |.|.....|  . .|..||||..|   |.||. ......  .|.||||||.|||||... ....|.||||||. .. .||.||| .
eegwslydilrelkrlglgldlwrisivNenyelcpsYPallvVPksisdellkrvarfrskgriPvlsyrhpnngavllRssqplvglllsrsledekl

IQAIIDANPNSSSLHLLDSRPKINAVANKAaHKGGYETTDNYPNIVYQFNNIQNIHVMRESLQKLLEALHSPAGVSSVLQGLDASSWLRHIHLVLEAGAF
..||....||.| |...| |||.||.||.| ..||.| .|.|||. ..| || ||||.||||||||.|. .  .....|  |. |.|| .|.|.||.  .
leailkllpnlskllivdlrpklnalanra.lgggvenedaypnaeliflnipnihvvreslqklldaclnvpdslnllslleesgwldliklilelavl

IAKALYTEGINVLVHCSDGWDRTAQTCSLASLMIDKYYRTIHGFMILIEKEWLSFGHKFTIRSGHINS--DSKEVSPIFTQFLDAVWQIMVQFPKSFEFN
|.| |  .. .||||||||||||.| .||| |..|.||||. ||..|||||||||||||  |.|| .|  ||||.||.| .|||.|||.. ||| .||||
ivklldlgnssvlvhcsdgwdrtsqlssLaqllldPyYRTleGFqvLiekeWlsfghkfadRlghleseidskefsPvFllFLdcvwqLlrqfPtaFeFn

ELFLLTIHDHLFSCQFGTFLGNNERDRKINKFSEKTYSLWGYIWSRLDDFTNPLFDNDTENYIMPKTEVSILSLWRGLYC
| .||...|||.||.|||||.|.|..| ....||.|.||| |..|| ..|.|||.| ... ...| ..|. | || ..|.
erlLlfLadhlyscrfgtFlfnsekerlelsvsertlslwsyllsrkseflnplYdpsslevllpslsvldlllWleyyl
subfamily_Dicty-MTMR1-like_pd Subfamily Dicty-MTMR1-like 120-501 1.6e-129 424.6 In-house 10-402 (404) alignment 
Range on Protein: 120-501
Range on HMM: 10-402/404.0
FVKSSGWNLYDSVVEYGRMGVPNE-HWVCTELNKDYELCETYSNTLFVPAKAEKSVVLGSAKFRSKGRLPVLSYYCQAKNSALCRSSQPLTYITR-RSQE
 | ..||..||.  || |.|...| .|  ...|.|||||||| ..| || .   . .  .|.||||||.||||.  . ||| . ||||||  .|. ||.|
svledgwliydaeeEykRlgikseseWriskinsdyelcetYPkllvvPesisDeelkkvasfRskgRiPvlswrhrsknstitRssqplvGltksrsee

DEAMIQAIIDANPNSSSLHLLDSRPKINAVANKAAHKgGYETTDNYPNIVYQFNNIQNIHVMRESLQKLLEALHSPAGV-SSVLQGLDASSWLRHIHLVL
|| .|..|  |......| .||.|||.|||||.|  . |||....| |   .| ||.||| .||||.|| .| .|     . .|. |. | || ||.|.|
dEklinsirkaktqletlyildarpkanavansakga.gyedisryenceieflnienihelreslkklkkavnsiiekeknwlselessrWldhiklll

EAGAFIAKALYTEGINVLVHCSDGWDRTAQTCSLASLMIDKYYRTIHGFMILIEKEWLSFGHKFTIRSGH-INSDSKEVSPIFTQFLDAVWQIMVQFPKS
|. . |.. . .|. .||||||||||||.| .||. |..| |||||.||..|||||||||||||. |.|.  . .|.| |||| ||.|.|.|.. |||.|
egskriveliekekssvlvhcsdgwDrtsqlsslsqllldpyyrtiegFivliekewlsfGhkfaqRigqttekssdersPiflqFidcvyqltkqfpts

FEFNELFLLTIHDHLFSCQFGTFLGNNERDRKINKFSEKTYSLWGYIWSRLDDFTNPLF---DNDTENYIMPKT-----EVSILSLWRGLYCCY
||||| ||..| |.| ||.||||| ..|..|. |.  ..| ||| .. .  ... |||.   ...... |  ..     ..  ..||. .|. .
FeFnekflikildalyscrfgtFLydsekeRqqnnlaketvslWalleankseylnplyilekkeqkenitssessssadikliklWseyylrw
Myotub-related Myotubularin-like phosphatase domain 107-447 8.6e-124 405.8 Pfam-A 1-351 (353) alignment
Myotub-related Myotubularin-like phosphatase domain 107-447 8.6e-124 405.8 In-house 1-351 (353) alignment
subfamily_Ank-MTMR1_pd Subfamily Ank-MTMR1 124-500 4.2e-100 327.4 In-house 14-403 (405) alignment 
Range on Protein: 124-500
Range on HMM: 14-403/405.0
SGWNLYDSVVEYGRMGVP----N---EHWVCTELNKDYELCETYSNTLFVPAKAEKSVVLGSAKFRSKGRLPVLSYYCQAKNSALCRSSQPLTYITR-RS
 ||..|.   || |. .     |    .|  |..||.|..| .|| .| | .||    .     ||||||.| ||.   . |... | ||||  | | | 
dgwevynqkkeylrfniyideenssncywkvtsinkeykmcssyssslvvlskaldkdlekifsfrskgripslswkdpssnasisrcsqplvgierarc

QEDEAMIQAIIDANPnSSSLHLLDSRPKINAVANKAAhKGGYETTDNYPNIVYQFNNIQNIHVMRESLQKLLEALHSPAGVSSV--------LQGLDASS
 |||    ..  . | | .|.|.|.|||.||.|| |    |.|   ||||    | || ||||.| ||.||  |..| |                .. . 
pedelycsslalsap.sktlylidarpklnaiantan.gagfenihnypncklvfmnipnihvirksleklvlamkssardkdhtestdmrfwgyieetg

WLRHIHLVLEAGAFIAKaLYTEGINVLVHCSDGWDRTAQTCSLASLMIDKYYRTIHGFMILIEKEWLSFGHKFTIRSGHINSDSKEVSPIFTQFLDAVWQ
|. ||. .||| .| |. |   |  .||||||||||| |  ||. ...| |||||.|| .|||||||||||||..| ||.  . .| |||| ||||...|
wishiksileaatfsae.lilkgnsilvhcsdgwdrtpqitsltqilldpyyrtivgfqvliekewlsfghkfslrlghlpgneeerspifqqfldccfq

IMVQFPKSFEFNELFLLTIHDHLFSCQFGTFLGNNERDRKINKFSEKTYSLWGYIWSRLDDFTNPLFDNDTENYIMPKTEVSILSLWRGLYCC
.. |||  |||   .|| | | . ||..|||| | |.||  ..   || |.|  .   .. | || .. .  . | ||     | ||.  |  
llsqfpllfeftpslllfisdnihsckygtflnncekdrvqdqvktktisiwsevnlnvnkflnpyynpqdiqsikpklysrclelwkacymr
subfamily_MTMR9_pd Subfamily MTMR9 122-499 1e-97 319.7 In-house 11-390 (393) alignment 
Range on Protein: 122-499
Range on HMM: 11-390/393.0
KSSGWNLYDSVVEYGRMGVPNEHWVCTELNKDYELCETYSNTLFVPAKAEKSVVLGSAKFRSKGRLPVLSYYCQAKNSALCRSSQPLTYI-TRRSQEDEA
.  |.. .|   |.... .. ..|  .. ||....|..| ... ||.. .   .  ||.||..||.|||||. ......| ||||||.   ..| .|||.
ledgysafdrenefaklisasdewRissvNknfkvcasypesvivPkaiddeelkasaafreggrfPvLsylhketkavllrssqplcgssgkrckedek

MIQAIIDANpnsSSLHLLDSRPKiNAVANKAAHKGGYETTDNYPNIVYQFNNIQNIHVMRESLQKLLEALHS-PAGVSSVLQGLDASSWLRHIHLVLEAG
...... ..   .    .| | | .|. |. .. || ||...|... .. ......... .||.||||| .      .. |. |..| || ... .||| 
llnlvlkkl...kkGlivdtrsk.saaenarskgggietevkysqwkkasrslesvasiqdslaklleacsdaglstdkflsrleksgwlsqvadlleaa

AFIAKALYTEGINVLVHCSDGWDRTAQTCSLASLMIDKYYRTIHGFMILIEKEWLSFGHKFTIRSGHINSDS---KEVSPIFTQFLDAVWQIMVQFPKSF
. .|..|..||. |.|| ..| | | |  ||| |..| ..||..||. |||.||.  || |. |  ..   .   |. .|.|  |||.|.||. ||| ||
lvvaqcldeegapvvvhgeeGlDatlqvtsLaqlildpdaRtvrgfealiereWiqaGHPFasRaskvaaketkkklsgpvfllFLDcvyqilsqfpasF

EFNELFLLTIHDHLFSCQFGTFLGNNERDRKINKFSEKTYSLWGYIWS--RLDDFTNPLFDNdTENYIMPKTEVSILSLWRGLYC
|||| .| ... | .|.||||||..||. || .| ..|| ||| |. .  .|..|.|||... ... |.|  .   |.||..||.
EFneelLillfehsyssqfgtflcdneaerkelklkkktvslwsyvnrpeklkqflnplyea.naeviwpsvapqslelWselyl
subfamily_MTMR3_pd Subfamily MTMR3 232-499 1.3e-86 284.1 In-house 172-440 (442) alignment 
Range on Protein: 232-499
Range on HMM: 172-440/442.0
SSSLHLLDSRPKINAVANKAaHKGGYETTDNYPNIVYQFNNIQNIHVMRESLQKLLEALHSPAGVSSVLQGLDASSWLRHIHLVLEAGAFIAKALYTEGI
. .| ..| |    |.||.| . ||.|... |||   .| .. ||| .|.|...| . |..    |  |  |.. .||...  .|.| . ...|. .|| 
kkkllivdarsytaafanra.kgGGceleeyypncevvflglanihavrksfnslrallsqspdesnwlsalektkWlqnlsvllkaavkvveavdkegr

NVLVHCSDGWDRTAQTCSLASLMIDKYYRTIHGFMILIEKEWLSFGHKFTIRSGHI-N-SDSKEVSPIFTQFLDAVWQIMVQFPKSFEFNELFLLTIHDH
 ||||||||||||.|  .|| |..|.||||..|| .|.|.|||.|||||. |.||  |  |..| .|.| |.|||| |.  ||| |||||| ||. .  |
pvlvhCsdGWdrttqivalakllldpyyrtleGfkvlvereWldfGhkfadrcghgenvddanercPvflqwldavhqlqrqfPtsfefneaflvklvqh

LFSCQFGTFLGNNERDRKINKFSEKTYSLWGYIWSRLDDFTNPLFDNDTENYIMPKTEVSILSLWRGLYC
 .|| |||||.|.|..|. .|  |.| |.| .. .. ....| |....||. ..|...|  |.||. .| 
tysclfGtflansekereeekvkertlsvWsllrakekeyrnllykekteavllpavsvrelklwsevyl
subfamily_MTMR5_pd Subfamily MTMR5 240-495 6.2e-56 182.2 In-house 204-476 (483) alignment 
Range on Protein: 240-495
Range on HMM: 204-476/483.0
SRPKINAVANKAAHKG-GYETTDNYPNIVYQFNNIQNihvMRESLQKLLEALHSPAG-----VSSVLQGLDASSWLRHIHLVLEAGAFIAKALYTEGINV
 . .. .. .|.  |.   |.. .   | ... .|..   .. |..||| |  .        ..| |. ...| ||. |. .|.  . ... |  .|  |
rkaaLYvlgeksqlknvksevdskaefipvelveirq...vkasfkkllraClpstaveeaesqsFlksvedseWlqqissllqlsgavvdlldlqgssv

LVHCSDGWDRTAQTCSLASLMIDKYYRTIHGFMILIEKEWLSFGHKFTIRSGHINSDSK-EVSPIFTQFLDAVWQIMVQFPKSFEFNELFLLTIHDHLFS
||   |||| |||  ||| |..| ||||..|| .|.|||||.|||.|| || ...| ..  ..|.| ||||.|.|.. ||| .||||. .| ..  |  |
lvslEdGwdvtaqvsslaqllldpyYRtleGFkvLveKEWLafGHrFtkrsnqtlsaqssgfaPvFlqFLDcvhqvsrqfPlafefndfylkflayhsvs

CQFGTFLGNNERDRKINKF----------SEKTYSLWGYIWS---RLDDFTNPLFDNDTENYIMPKTEVSILSLWR
..| ||| . | .|  .             . . |.| ||     |   | | |...| .. . |...|| |..| 
nrfrtfllDseyerlesgllyeekaekrakkagksvwdyidrqhkrspifynflyspdesevlrPssnvsslkvWd
subfamily_MTMR10_pd Subfamily MTMR10 300-467 5e-43 139.3 In-house 156-323 (380) alignment 
Range on Protein: 300-467
Range on HMM: 156-323/380.0
LQGLDASSWLRHIHLVLEAGAFIAKALYTEGINVLVHCSDGWDRTAQTCSLASLMIDKYYRTIHGFMILIEKEWLSFGHKFTIRSGHINSDSKEVSPIFT
|  |. ..||  ..|.|.    ..|...... .|..  |.| |     .|||.||.| .|||| ||  ||.||| . ||.|. | ||| ...|. ||.| 
lssLektrWLayvrlclstasdavktvvekkrsvilqesegrDlscvvaSLaqlmldphyrtisGfqsliqkewvaaghpfldrlghikpseksespvfl

QFLDAVWQIMVQFPKSFEFNELFLLTIHDHLFSCQFGTFLGNNERDRKINKFSEKTYSLWGYIWSRLD
 ||| |.| . |||..|||.| ||....|. .|. |.||| |.|. |. .. | .   .  . . . |
lFldcvdqlleqfpseFeFtetfLialwdsshsgifltflfnseeqrlkavvsssplliakselkend
subfamily_pats1_pd Subfamily pats1 393-475 4.8e-23 73.4 In-house 551-633 (691) alignment 
Range on Protein: 393-475
Range on HMM: 551-633/691.0
EVSPIFTQFLDAVWQIMVQFPKSFEFNELFLLTIHDHLFSCQFGTFLGNNERDRKINKFSEKTYSLWGYIWSRLDDFTNPLFD
  |||| ||||.|||.  .||  ||||| .||.. .. || .||.|| .. ...  .|. ... |.| .|      |.| |. 
sfsPifvqfldlvwqlqkefPfhfefneslllllvkesfssrfGnflyseakrdserkvlkrsksiwsfinqnksrfinllyk
subfamily_MTMR3_pd Subfamily MTMR3 130-229 4.3e-21 68.2 In-house 28-129 (442) alignment 
Range on Protein: 130-229
Range on HMM: 28-129/442.0
DSVVEYGRMG-VPNEHWVCTELNKDYELCETYSNTLFVPAKAEKSVVLGSAKFRSKGRLPVLSYYCQAKNSALCRSSQP-LTYITRRSQEDEAMIQAIID
.   |. |.|   .|.|  ...|.|..||..| ..| ||.. . . .  .|.||| .|||.. . .. . ..| |.||| ..... |..||| ...|| .
klkeeverlGfdlkeawrisdvnsdfklCssyPkklivPksitdddlkkvasfrslkrlPavvwrhkkngavlarcsqPevgwlgWrnaedekllkaiak

AN
| 
ac
subfamily_pats1_pd Subfamily pats1 269-391 4e-19 60.4 In-house 339-464 (691) alignment 
Range on Protein: 269-391
Range on HMM: 339-464/691.0
QFNNIQNIHVMRESLQKLLEALHSPAGVSSVLQGLDASSWLRHIHLVLEAGAFIAKALyTEGINVLVH-CSDGWDRTAQT---CSLASLMIDKYYRTIHG
.| ..   . ..|   .||... |  |  .  . .  | |.  . |.|||   ... |  ||  ||..  .|. . . .     ||| .. | .|||. |
iflslPtrekveerffdllqsilsldgsddewkeieeskwvdsvkllleaavkvsnll.deGssvllknsidsPlieldlasisslaqvlsdPfyrtldG

FMILIEKEWLSFGHKFTIRSGHINSDS
|..||||||||.|. |. .. | .|| 
fkvliekewlsyGfPfskinyhkesdd
FYVE FYVE zinc finger 610-670 5e-14 42.0 Pfam-A 3-65 (69) alignment 
Range on Protein: 610-670
Range on HMM: 3-65/69.0
WTPLRVASQCG-CGSAFTFSKRKYHCSYCGTVVCSTCGSYHAPLR-YLATSTTSHRVCKSCSK
| . . |..|  |...|....|. ||  || ||||.| | ...     . .... ||||.| .
wvddaeakkCeiCakkFsltrrrhhCrlCGkvvCskCsskrvekleeesaeekevrvCkeCle
PTPc_DSPc_SM00012 268-430 7.8e-11 37.5 In-house 5-104 (105) alignment 
Range on Protein: 268-430
Range on HMM: 5-104/105.0
YQFNNIQNIHVMRESlQ---KLLEALHSPAGVSSVlqgldasswlrhihlvleagafiakalyteGINVLVHCSDGWDRTAQTCSLASLMIDKYYRTihg
|....... .| .|| .   .||.|...    |.                               . .|.||||.|..||.. . |. |. . ...|   
yhytgwpdhgvPees.dsilellravkknknkses..............................skpvvVhCsaGvgRtgtfvaldillqqleket...

fmiliekewlsfghkftirsghinsdskevspIFTQFLDAVWQIMVQFPKSFEFNELFLLTIHDHL
                                 . .... |.... | |......| .|  .. .|
................................kevdifqivkelrkqRpgmvqteeqylflyrall
subfamily_MTMR5_pd Subfamily MTMR5 132-207 5.4e-09 27.4 In-house 11-93 (483) alignment 
Range on Protein: 132-207
Range on HMM: 11-93/483.0
VVEYGRMGVP-------NEHWVCTELNKDYELCETYSNTLFVPAKAEKSVVLGSAKFRSKGRLPVLSYYCQAKNSALCRSSQP
| .| |.|.        ....  .| ||.|..|..| . . || . . . .   ||   ..||||  .  . ... | ||...
vqdykRlGlgalngaskrgkfrisevNkkytvcrsYPalivvPsevsddsiarvakcfrqnRlPvvtWrhernkalLiRsggf
0045098 (Phosphotyrosine protein) phosphatases II 299-382 9.8e-08 27.2 In-house 169-269 (278) alignment 
Range on Protein: 299-382
Range on HMM: 169-269/278.0
VLQGLDASSWLRHIHLVLEAGAFIAKALYT------EGINVLVHCSDGWDRTAQTCSLASLMID-----------KYYRTIHGFMILIEKEWLSFGHKFT
|      .|.|...  ..|| ...|. |..      .|  |||||| |..||.  . .  ..             |..|.  .....  .|.. | ..| 
vpslpilksflellefirealkllaslllsslllldsggpvlVHCsaGvgRtGtlvaaylmlelleggvdlleavkelrsqRpglavqnleqyrflyefl

I
.
l
subfamily_pats1_pd Subfamily pats1 126-208 1.1e-07 22.7 In-house 6-90 (691) alignment 
Range on Protein: 126-208
Range on HMM: 6-90/691.0
WNLYDSVVEYGRMGVPNEH-WVCTELNkDYELCETYSNTLFVPAKAEKSVVLGSAKFRSKgRLPVLSYYCQAKNSA---LCRSSQPL
.. |  ..|. |...  .. |  .|.  . .|.| | ..  ||      ..  ... ||  ..||||.  |.. |.   .|   ||.
fdiyslliegqrlkldldkdwrvvefl.srdlseiyPkrilvPklvsdellvsyvrkrss.kiPvlswsnqnnksslfricvynqpf
0049772 (Phosphotyrosine protein) phosphatases II 313-356 1.4e-06 23.8 In-house 197-238 (314) alignment 
Range on Protein: 313-356
Range on HMM: 197-238/314.0
HLVLEAGAFIAKAlyTEGINVLVHCSDGWDRTAQTCSLASLMID
  ..|. .|| .|   .| .|||||..|..||.  . .| ||. 
edfdeflefieea..dkggpvlvHCkaGkgRtgtfvvaaylmkl
subfamily_DSP3_pd Subfamily DSP3 317-357 1.4e-06 22.0 In-house 84-123 (162) alignment 
Range on Protein: 317-357
Range on HMM: 84-123/162.0
EAGAFIAKALYTEGINVLVHCSDGWDRTAqTCSLASLMIDK
.| .||..|| ..   |||||  |  | | |. || ||| .
taakfidealsqkegkvlvhcvvGvsRsa.tlvlayLmirr
IBR IBR domain 618-652 1.4e-06 16.6 Pfam-A 20-62 (64) alignment 
Range on Protein: 618-652
Range on HMM: 20-62/64.0
QC---GCGSAFTFSKRKYH----CSYCGTVVCSTCGS-YHAPL
.|   .|..... .. . .    || ||. .|. |.. .|..|
wCprpdCeaiiekeegakkssvtCskCgfefCflCkkewHegl
0044763 (Phosphotyrosine protein) phosphatases II 313-354 4.8e-06 21.9 In-house 93-133 (178) alignment 
Range on Protein: 313-354
Range on HMM: 93-133/178.0
HLVLEAGAFIAKALYTEGINVLVHCSDGWDRTAQTCsLASLM
  .||. .|| .|| ..| .|||||| |..|..  . .| ||
ehflefvefieealdekggpvlVHCsaGvgRsgtlv.aaylm
0051429 (Phosphotyrosine protein) phosphatases II 306-354 6.8e-06 21.5 In-house 128-174 (272) alignment 
Range on Protein: 306-354
Range on HMM: 128-174/272.0
SSWLRHI---HLVLEAGAFIAKalyteGINVLVHCSDGWDRTAQTCSLASLM
 .|. |    . .||. .....     | .|||||| |.|||.  . |  |.
tdwpdhgvpqeallellellld.....ggpvlvHCsaGkdRTGtvvalllll
0051082 (Phosphotyrosine protein) phosphatases II 318-357 8.2e-06 21.0 In-house 80-119 (151) alignment 
Range on Protein: 318-357
Range on HMM: 80-119/151.0
AGAFIAKALYTEGINVLVHCSDGWDRTAQTCSLASLMIDK
. .|. ..| ... .|||||| |..||.  . |  .. . 
vleflellldkkngpvlvHCsaGkgRTGtlvalylmllgv
FYVE_2 FYVE-type zinc finger 619-677 9.4e-06 14.0 Pfam-A 57-109 (118) alignment 
Range on Protein: 619-677
Range on HMM: 57-109/118.0
C-GCGSAFTFSK-RKYHCSYCGTVVCSTCGSYhaplrylaTSTTSHRVCKSCSKMSNISDQ
|  | . |.. .  | .|. | . || .|...        . . .  .||.||.   .  .
CllCleefkllvnskrqCldCkknvCkkCsve........skkekgwlCklcseaRevkkk