Gene OCA-1 in Amphimedon queenslandica

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family OCA
Subfamily OCA
Protein sequence
ID Type Fasta BLAST phosphatome Note
AqueP035_AA protein Get Run
AqueP035_AA_1-119 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_OCA_pd Subfamily OCA 1-120 1.2e-46 149.4 In-house 165-278 (282) alignment 
Range on Protein: 1-120
Range on HMM: 165-278/282.0
MLKLLLSHEENLPVLIhcvygkDRTGVLVALILDCIGVESETIAmDY-ASSEDGLVSMRNEMYDDLIVHWGMA-EHSCRAKADTMLKVLNEiDKRYGSTS
.|.|||..|||||.||      ||.|...|||||...||.|||| |. ||||..|||.|||...||......| |.||.||.||.||||.. ||.|||||
llrlllpeeenlpfLi......drlglktaliLdaeeveretia.dflasseiklvslrnevlkdlldndnyavelscqaktdtvlkvLrk.dkkygsts

QYLKSIGFTLEDQESLKSILLH
.||..||||||||||||||||.
iyleyigFtledqeslksilli
0051429 (Phosphotyrosine protein) phosphatases II 2-119 1.1e-25 86.3 In-house 144-272 (272) alignment 
Range on Protein: 2-119
Range on HMM: 144-272/272.0
LKLLLSheeNLPVLIHCVYGKDRTGVLVALILDCIGVESETIAMDYASSEDGLVSMRNEMYDDLI--------------VHWGMAEHSCRAKADTMLKVL
|.|||.   . |||.||  ||||||..|||.|   ||. |||. ||. .. .|   ..|. .                 . . ...    ..|...| .|
lellld...ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlyleeaveelraqrpgavqteeqylflyeallellrsllsvraeyllaal

NEIDKRYGSTSQYLKSIGFTLEDQESLKSILL
..||..|||. .||...|.. |..| |...||
daideeyGsvegYLrdlglseeelerLrellL
Y_phosphatase3 Tyrosine phosphatase family 3-50 2.2e-16 55.3 Pfam-A 118-163 (164) alignment 
Range on Protein: 3-50
Range on HMM: 118-163/164.0
KLLLSHEeNlPVLIHCVYGKDRTGVLVALILDCIGVESETIAMDYASS
..|...| . |||.||  |||||||..||.|. .||..|||| ||. .
ealaeee.g.pvlfHCtaGKDRTGvvaalllsllgvdeetiaaDYllt
0051082 (Phosphotyrosine protein) phosphatases II 5-63 3.5e-12 41.7 In-house 87-144 (151) alignment 
Range on Protein: 5-63
Range on HMM: 87-144/151.0
LLShEENLPVLIHCVYGKDRTGVLVALILDCIGVESETIAMDYASSEDGLVSMRNEMYD
||.  .| |||.||  ||.|||.||||.| . ||  |..  .| ..  |.|   .... 
lld.kkngpvlvHCsaGkgRTGtlvalylmllgvsleealeeyrlkrpgvvqpnqqflf
Y_phosphatase3C Tyrosine phosphatase family C-terminal region 77-119 7.3e-12 34.7 Pfam-A 25-68 (68) alignment 
Range on Protein: 77-119
Range on HMM: 25-68/68.0
RAKADTMLKVLNEIDKRYGSTSQYL-KSIGFTLEDQESLKSILL
 ......  .| .||.||||  .|| . .|.. ||.| |.. ||
gvreeyleaaldtideryGsvegYLeeaLGlseedierLRerlL
0049772 (Phosphotyrosine protein) phosphatases II 2-50 3e-10 35.8 In-house 203-253 (314) alignment 
Range on Protein: 2-50
Range on HMM: 203-253/314.0
LKLLLSHEENLPVLIHCVYGKDRTG--VLVALILDCIGVESETIAMDYASS
|......... |||.||  ||.|||  |..|... . ||  |..  |. . 
lefieeadkggpvlvHCkaGkgRtgtfvvaaylmkllgvsleealedvrlk
0042113 (Phosphotyrosine protein) phosphatases II 8-47 5.5e-09 31.3 In-house 173-218 (245) alignment 
Range on Protein: 8-47
Range on HMM: 173-218/245.0
HEENLPVLIHCVYGKDRTGVLVALIL------DCIGVESETIAMDY
  .| |||.||  |..|||...|. |         ||  | .  ..
edsngpvlVHCsaGvgRtGtfiaaylmleqlekelgvsleeavkel
0045450 (Phosphotyrosine protein) phosphatases II 9-58 9e-09 31.0 In-house 232-283 (307) alignment 
Range on Protein: 9-58
Range on HMM: 232-283/307.0
EENLPVLIHCVYGKDRTGVLVALILDCIGVESETIA--MDYASSEDGLVSMR
 .. |||.||  |..|||...|. | . ..|.| .   .|. .  . | ..|
pkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqR
0036282 (Phosphotyrosine protein) phosphatases II 6-39 1.2e-08 30.3 In-house 99-132 (174) alignment 
Range on Protein: 6-39
Range on HMM: 99-132/174.0
LSHEENLPVLIHCVYGKDRTGVLVALILDCIGVE
||. .. |||.||  |..|||.|||. | . | .
lsedpggpvlVHCsaGvgRtGtlvaaylmlrgll
0040439 (Phosphotyrosine protein) phosphatases II 9-42 2.3e-08 29.4 In-house 177-216 (249) alignment 
Range on Protein: 9-42
Range on HMM: 177-216/249.0
EENLPVLIHCVYGKDRTGVLVALILD------CIGVESET
... |||.||  |..|||...|. |         ||  | 
pkggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdlee
0043147 (Phosphotyrosine protein) phosphatases II 7-38 3.7e-08 28.8 In-house 96-127 (172) alignment 
Range on Protein: 7-38
Range on HMM: 96-127/172.0
SHEENLPVLIHCVYGKDRTGVLVALILDCIGV
  ... |||.||..|..|||.|||. | . |.
alspggpvlVHCsaGvgRtgtlvaaylmllgl
0049260 (Phosphotyrosine protein) phosphatases II 7-38 4.2e-08 28.5 In-house 85-116 (152) alignment 
Range on Protein: 7-38
Range on HMM: 85-116/152.0
SHEENLPVLIHCVYGKDRTGVLVALILDCIGV
 .... |||.||..|..|||.|||. | . ||
aldkggpvlVHCsaGvgRtgtlvaaylmllgv
0043336 (Phosphotyrosine protein) phosphatases II 9-42 4.3e-08 28.4 In-house 208-247 (278) alignment 
Range on Protein: 9-42
Range on HMM: 208-247/278.0
EENLPVLIHCVYGKDRTGVLVALILD------CIGVESET
 .| |||.||. |..|||...|| |         ||  | 
dsngpvlVHCsaGvgRTGtfialyllleqlekeggvdlee
0039614 (Phosphotyrosine protein) phosphatases II 9-35 6.1e-08 28.0 In-house 220-246 (297) alignment 
Range on Protein: 9-35
Range on HMM: 220-246/297.0
EENLPVLIHCVYGKDRTGVLVALILDC
... |||.||. |..|||...|. | .
pkggpvlVHCsaGvgRtGtfiaaylml
0048076 (Phosphotyrosine protein) phosphatases II 8-33 7.2e-08 27.8 In-house 78-103 (145) alignment 
Range on Protein: 8-33
Range on HMM: 78-103/145.0
HEENLPVLIHCVYGKDRTGVLVALIL
..|. |||.||  |..|||.|||. |
lkeggpvlVHCsaGvgRtgtlvaayl
0045098 (Phosphotyrosine protein) phosphatases II 8-38 8.7e-08 27.4 In-house 203-233 (278) alignment 
Range on Protein: 8-38
Range on HMM: 203-233/278.0
HEENLPVLIHCVYGKDRTGVLVALILDCIGV
.... |||.|| .|..|||.|||. | .  .
ldsggpvlVHCsaGvgRtGtlvaaylmlell
0048179 (Phosphotyrosine protein) phosphatases II 8-33 1e-07 27.3 In-house 80-105 (144) alignment 
Range on Protein: 8-33
Range on HMM: 80-105/144.0
HEENLPVLIHCVYGKDRTGVLVALIL
.||. |||.|| .|..|||.|||. |
leeggpvlVHCsaGvgRtgtlvaayl
0037934 (Phosphotyrosine protein) phosphatases II 8-38 1.1e-07 27.2 In-house 175-207 (243) alignment 
Range on Protein: 8-38
Range on HMM: 175-207/243.0
HEENLPVLIHCVYGKDRTGVLVALILDCI--GV
  .. |||.||. |..|||.|.|. | .   ||
ldsggpvlVHCsaGvgRtGtliaaylmllllgv
0041856 (Phosphotyrosine protein) phosphatases II 9-33 1.6e-07 26.6 In-house 107-131 (182) alignment 
Range on Protein: 9-33
Range on HMM: 107-131/182.0
EENLPVLIHCVYGKDRTGVLVALIL
||. |||.|| .|..|||.|||. |
eeggpvlVHCsaGvgRtgtlvaayl
0044763 (Phosphotyrosine protein) phosphatases II 9-33 1.6e-07 26.6 In-house 108-132 (178) alignment 
Range on Protein: 9-33
Range on HMM: 108-132/178.0
EENLPVLIHCVYGKDRTGVLVALIL
|.. |||.|| .|..|.|.|||. |
ekggpvlVHCsaGvgRsgtlvaayl
PTPc_DSPc_SM00012 10-61 1.7e-07 26.8 In-house 37-89 (105) alignment 
Range on Protein: 10-61
Range on HMM: 37-89/105.0
E-NLPVLIHCVYGKDRTGVLVALILDCIGVESETIAMDYASSEDGLVSMRNEM
| . ||..||  | .|||..||| . .  .|.||  .|       | ..|. |
esskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgm
0040438 (Phosphotyrosine protein) phosphatases II 9-35 3.2e-07 25.4 In-house 207-233 (317) alignment 
Range on Protein: 9-35
Range on HMM: 207-233/317.0
EENLPVLIHCVYGKDRTGVLVALILDC
... |||.||. |..|||...|. | .
dpggpvlVHCsaGvgRtGtfiaaylml
Y_phosphatase2 Tyrosine phosphatase family 2-32 3.3e-07 22.2 Pfam-A 83-112 (165) alignment 
Range on Protein: 2-32
Range on HMM: 83-112/165.0
LKLLLShEENLPVLIHCVYGKDRTGVLVALI
|||||  .|| |||.||  || |||.... .
lkllln.kenypvllhckrGkhrtglvigcl
0046846 (Phosphotyrosine protein) phosphatases II 9-36 3.5e-07 25.7 In-house 107-134 (176) alignment 
Range on Protein: 9-36
Range on HMM: 107-134/176.0
EENLPVLIHCVYGKDRTGVLVALILDCI
.|. |||.||. |. |||.|||. | . 
keggpvlVHCsaGigRtgtlvaayllel
0038934 (Phosphotyrosine protein) phosphatases II 9-33 1e-06 24.0 In-house 113-137 (194) alignment 
Range on Protein: 9-33
Range on HMM: 113-137/194.0
EENLPVLIHCVYGKDRTGVLVALIL
 ..  |..||..|. |||.|||  |
dpggvvaVHCkaGlgRtGtlvaaYL
0050432 (Phosphotyrosine protein) phosphatases II 5-46 1.6e-06 23.1 In-house 226-266 (308) alignment 
Range on Protein: 5-46
Range on HMM: 226-266/308.0
LLSHEENLPVLIHCVYGKDRTGVLVALILDCIGVESEtIAMD
. .. .. |...||  |  |||...|| | .  .| |   .|
vrkslpggpivVHCsaGvGRtGtfialdllleqleke.ggvd
0036941 (Phosphotyrosine protein) phosphatases II 10-40 1.6e-06 23.1 In-house 206-236 (297) alignment 
Range on Protein: 10-40
Range on HMM: 206-236/297.0
ENLPVLIHCVYGKDRTGVLVALILDCIGVES
.. |||.||. |. |.|...|. | .  .|.
sggpvlVHCsaGvgRsgtfiaadlmlqqled
0046845 (Phosphotyrosine protein) phosphatases II 9-46 1.7e-06 23.1 In-house 202-241 (284) alignment 
Range on Protein: 9-46
Range on HMM: 202-241/284.0
EENLPVLIHCVYGKDRTGVLVALILDCIGVESETI--AMD
. . |...||  |. |||...|| | .  .| | .   .|
pgggpivVHCsaGvgRtGtfialdllleqlekeglllgvd
0051299 (Phosphotyrosine protein) phosphatases II 9-41 1.7e-06 23.2 In-house 217-249 (288) alignment 
Range on Protein: 9-41
Range on HMM: 217-249/288.0
EENLPVLIHCVYGKDRTGVLVALILDCIGVESE
  . ||..||  |..|||...|| | .  .| |
sgggpvvVHCsaGvgRtgtfialdllleqleke
0047943 (Phosphotyrosine protein) phosphatases II 10-37 2.6e-06 22.6 In-house 204-231 (273) alignment 
Range on Protein: 10-37
Range on HMM: 204-231/273.0
ENLPVLIHCVYGKDRTGVLVALILDCIG
.| ||..||. |. |||...|| | .  
sngpvvVHCsaGvgRtgtfialdllldq