Gene OCA-1 in Amphimedon queenslandica

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family OCA
Subfamily OCA
Protein sequence
ID Type Fasta BLAST phosphatome Note
AqueP035_AA protein Get Run
AqueP035_AA_1-119 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_OCA_pd Subfamily OCA 1-120 1.2e-46 149.4 In-house 165-278 (282) alignment
Range on Protein: 1-120
Range on HMM: 165-278/282.0
MLKLLLSHEENLPVLIhcvygkDRTGVLVALILDCIGVESETIAmDY-ASSEDGLVSMRNEMYDDLIVHWGMA-EHSCRAKADTMLKVLNEiDKRYGSTS
.|.|||..|||||.||      ||.|...|||||...||.|||| |. ||||..|||.|||...||......| |.||.||.||.||||.. ||.|||||
llrlllpeeenlpfLi......drlglktaliLdaeeveretia.dflasseiklvslrnevlkdlldndnyavelscqaktdtvlkvLrk.dkkygsts

QYLKSIGFTLEDQESLKSILLH
.||..||||||||||||||||.
iyleyigFtledqeslksilli

0051429 (Phosphotyrosine protein) phosphatases II 2-119 1.1e-25 86.3 In-house 144-272 (272) alignment
Range on Protein: 2-119
Range on HMM: 144-272/272.0
LKLLLSheeNLPVLIHCVYGKDRTGVLVALILDCIGVESETIAMDYASSEDGLVSMRNEMYDDLI--------------VHWGMAEHSCRAKADTMLKVL
|.|||.   . |||.||  ||||||..|||.|   ||. |||. ||. .. .|   ..|. .                 . . ...    ..|...| .|
lellld...ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlyleeaveelraqrpgavqteeqylflyeallellrsllsvraeyllaal

NEIDKRYGSTSQYLKSIGFTLEDQESLKSILL
..||..|||. .||...|.. |..| |...||
daideeyGsvegYLrdlglseeelerLrellL

Y_phosphatase3 Tyrosine phosphatase family 3-50 2.2e-16 55.3 Pfam-A 118-163 (164) alignment
Range on Protein: 3-50
Range on HMM: 118-163/164.0
KLLLSHEeNlPVLIHCVYGKDRTGVLVALILDCIGVESETIAMDYASS
..|...| . |||.||  |||||||..||.|. .||..|||| ||. .
ealaeee.g.pvlfHCtaGKDRTGvvaalllsllgvdeetiaaDYllt

0051082 (Phosphotyrosine protein) phosphatases II 5-63 3.5e-12 41.7 In-house 87-144 (151) alignment
Range on Protein: 5-63
Range on HMM: 87-144/151.0
LLShEENLPVLIHCVYGKDRTGVLVALILDCIGVESETIAMDYASSEDGLVSMRNEMYD
||.  .| |||.||  ||.|||.||||.| . ||  |..  .| ..  |.|   .... 
lld.kkngpvlvHCsaGkgRTGtlvalylmllgvsleealeeyrlkrpgvvqpnqqflf

Y_phosphatase3C Tyrosine phosphatase family C-terminal region 77-119 7.3e-12 34.7 Pfam-A 25-68 (68) alignment
Range on Protein: 77-119
Range on HMM: 25-68/68.0
RAKADTMLKVLNEIDKRYGSTSQYL-KSIGFTLEDQESLKSILL
 ......  .| .||.||||  .|| . .|.. ||.| |.. ||
gvreeyleaaldtideryGsvegYLeeaLGlseedierLRerlL

0049772 (Phosphotyrosine protein) phosphatases II 2-50 3e-10 35.8 In-house 203-253 (314) alignment
Range on Protein: 2-50
Range on HMM: 203-253/314.0
LKLLLSHEENLPVLIHCVYGKDRTG--VLVALILDCIGVESETIAMDYASS
|......... |||.||  ||.|||  |..|... . ||  |..  |. . 
lefieeadkggpvlvHCkaGkgRtgtfvvaaylmkllgvsleealedvrlk

0042113 (Phosphotyrosine protein) phosphatases II 8-47 5.5e-09 31.3 In-house 173-218 (245) alignment
Range on Protein: 8-47
Range on HMM: 173-218/245.0
HEENLPVLIHCVYGKDRTGVLVALIL------DCIGVESETIAMDY
  .| |||.||  |..|||...|. |         ||  | .  ..
edsngpvlVHCsaGvgRtGtfiaaylmleqlekelgvsleeavkel

0045450 (Phosphotyrosine protein) phosphatases II 9-58 9e-09 31.0 In-house 232-283 (307) alignment
Range on Protein: 9-58
Range on HMM: 232-283/307.0
EENLPVLIHCVYGKDRTGVLVALILDCIGVESETIA--MDYASSEDGLVSMR
 .. |||.||  |..|||...|. | . ..|.| .   .|. .  . | ..|
pkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqR

0036282 (Phosphotyrosine protein) phosphatases II 6-39 1.2e-08 30.3 In-house 99-132 (174) alignment
Range on Protein: 6-39
Range on HMM: 99-132/174.0
LSHEENLPVLIHCVYGKDRTGVLVALILDCIGVE
||. .. |||.||  |..|||.|||. | . | .
lsedpggpvlVHCsaGvgRtGtlvaaylmlrgll

0040439 (Phosphotyrosine protein) phosphatases II 9-42 2.3e-08 29.4 In-house 177-216 (249) alignment
Range on Protein: 9-42
Range on HMM: 177-216/249.0
EENLPVLIHCVYGKDRTGVLVALILD------CIGVESET
... |||.||  |..|||...|. |         ||  | 
pkggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdlee

0043147 (Phosphotyrosine protein) phosphatases II 7-38 3.7e-08 28.8 In-house 96-127 (172) alignment
Range on Protein: 7-38
Range on HMM: 96-127/172.0
SHEENLPVLIHCVYGKDRTGVLVALILDCIGV
  ... |||.||..|..|||.|||. | . |.
alspggpvlVHCsaGvgRtgtlvaaylmllgl

0049260 (Phosphotyrosine protein) phosphatases II 7-38 4.2e-08 28.5 In-house 85-116 (152) alignment
Range on Protein: 7-38
Range on HMM: 85-116/152.0
SHEENLPVLIHCVYGKDRTGVLVALILDCIGV
 .... |||.||..|..|||.|||. | . ||
aldkggpvlVHCsaGvgRtgtlvaaylmllgv

0043336 (Phosphotyrosine protein) phosphatases II 9-42 4.3e-08 28.4 In-house 208-247 (278) alignment
Range on Protein: 9-42
Range on HMM: 208-247/278.0
EENLPVLIHCVYGKDRTGVLVALILD------CIGVESET
 .| |||.||. |..|||...|| |         ||  | 
dsngpvlVHCsaGvgRTGtfialyllleqlekeggvdlee

0039614 (Phosphotyrosine protein) phosphatases II 9-35 6.1e-08 28.0 In-house 220-246 (297) alignment
Range on Protein: 9-35
Range on HMM: 220-246/297.0
EENLPVLIHCVYGKDRTGVLVALILDC
... |||.||. |..|||...|. | .
pkggpvlVHCsaGvgRtGtfiaaylml

0048076 (Phosphotyrosine protein) phosphatases II 8-33 7.2e-08 27.8 In-house 78-103 (145) alignment
Range on Protein: 8-33
Range on HMM: 78-103/145.0
HEENLPVLIHCVYGKDRTGVLVALIL
..|. |||.||  |..|||.|||. |
lkeggpvlVHCsaGvgRtgtlvaayl

0045098 (Phosphotyrosine protein) phosphatases II 8-38 8.7e-08 27.4 In-house 203-233 (278) alignment
Range on Protein: 8-38
Range on HMM: 203-233/278.0
HEENLPVLIHCVYGKDRTGVLVALILDCIGV
.... |||.|| .|..|||.|||. | .  .
ldsggpvlVHCsaGvgRtGtlvaaylmlell

0048179 (Phosphotyrosine protein) phosphatases II 8-33 1e-07 27.3 In-house 80-105 (144) alignment
Range on Protein: 8-33
Range on HMM: 80-105/144.0
HEENLPVLIHCVYGKDRTGVLVALIL
.||. |||.|| .|..|||.|||. |
leeggpvlVHCsaGvgRtgtlvaayl

0037934 (Phosphotyrosine protein) phosphatases II 8-38 1.1e-07 27.2 In-house 175-207 (243) alignment
Range on Protein: 8-38
Range on HMM: 175-207/243.0
HEENLPVLIHCVYGKDRTGVLVALILDCI--GV
  .. |||.||. |..|||.|.|. | .   ||
ldsggpvlVHCsaGvgRtGtliaaylmllllgv

0041856 (Phosphotyrosine protein) phosphatases II 9-33 1.6e-07 26.6 In-house 107-131 (182) alignment
Range on Protein: 9-33
Range on HMM: 107-131/182.0
EENLPVLIHCVYGKDRTGVLVALIL
||. |||.|| .|..|||.|||. |
eeggpvlVHCsaGvgRtgtlvaayl

0044763 (Phosphotyrosine protein) phosphatases II 9-33 1.6e-07 26.6 In-house 108-132 (178) alignment
Range on Protein: 9-33
Range on HMM: 108-132/178.0
EENLPVLIHCVYGKDRTGVLVALIL
|.. |||.|| .|..|.|.|||. |
ekggpvlVHCsaGvgRsgtlvaayl

PTPc_DSPc_SM00012 10-61 1.7e-07 26.8 In-house 37-89 (105) alignment
Range on Protein: 10-61
Range on HMM: 37-89/105.0
E-NLPVLIHCVYGKDRTGVLVALILDCIGVESETIAMDYASSEDGLVSMRNEM
| . ||..||  | .|||..||| . .  .|.||  .|       | ..|. |
esskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgm

0040438 (Phosphotyrosine protein) phosphatases II 9-35 3.2e-07 25.4 In-house 207-233 (317) alignment
Range on Protein: 9-35
Range on HMM: 207-233/317.0
EENLPVLIHCVYGKDRTGVLVALILDC
... |||.||. |..|||...|. | .
dpggpvlVHCsaGvgRtGtfiaaylml

Y_phosphatase2 Tyrosine phosphatase family 2-32 3.3e-07 22.2 Pfam-A 83-112 (165) alignment
Range on Protein: 2-32
Range on HMM: 83-112/165.0
LKLLLShEENLPVLIHCVYGKDRTGVLVALI
|||||  .|| |||.||  || |||.... .
lkllln.kenypvllhckrGkhrtglvigcl

0046846 (Phosphotyrosine protein) phosphatases II 9-36 3.5e-07 25.7 In-house 107-134 (176) alignment
Range on Protein: 9-36
Range on HMM: 107-134/176.0
EENLPVLIHCVYGKDRTGVLVALILDCI
.|. |||.||. |. |||.|||. | . 
keggpvlVHCsaGigRtgtlvaayllel

0038934 (Phosphotyrosine protein) phosphatases II 9-33 1e-06 24.0 In-house 113-137 (194) alignment
Range on Protein: 9-33
Range on HMM: 113-137/194.0
EENLPVLIHCVYGKDRTGVLVALIL
 ..  |..||..|. |||.|||  |
dpggvvaVHCkaGlgRtGtlvaaYL

0050432 (Phosphotyrosine protein) phosphatases II 5-46 1.6e-06 23.1 In-house 226-266 (308) alignment
Range on Protein: 5-46
Range on HMM: 226-266/308.0
LLSHEENLPVLIHCVYGKDRTGVLVALILDCIGVESEtIAMD
. .. .. |...||  |  |||...|| | .  .| |   .|
vrkslpggpivVHCsaGvGRtGtfialdllleqleke.ggvd

0036941 (Phosphotyrosine protein) phosphatases II 10-40 1.6e-06 23.1 In-house 206-236 (297) alignment
Range on Protein: 10-40
Range on HMM: 206-236/297.0
ENLPVLIHCVYGKDRTGVLVALILDCIGVES
.. |||.||. |. |.|...|. | .  .|.
sggpvlVHCsaGvgRsgtfiaadlmlqqled

0046845 (Phosphotyrosine protein) phosphatases II 9-46 1.7e-06 23.1 In-house 202-241 (284) alignment
Range on Protein: 9-46
Range on HMM: 202-241/284.0
EENLPVLIHCVYGKDRTGVLVALILDCIGVESETI--AMD
. . |...||  |. |||...|| | .  .| | .   .|
pgggpivVHCsaGvgRtGtfialdllleqlekeglllgvd

0051299 (Phosphotyrosine protein) phosphatases II 9-41 1.7e-06 23.2 In-house 217-249 (288) alignment
Range on Protein: 9-41
Range on HMM: 217-249/288.0
EENLPVLIHCVYGKDRTGVLVALILDCIGVESE
  . ||..||  |..|||...|| | .  .| |
sgggpvvVHCsaGvgRtgtfialdllleqleke

0047943 (Phosphotyrosine protein) phosphatases II 10-37 2.6e-06 22.6 In-house 204-231 (273) alignment
Range on Protein: 10-37
Range on HMM: 204-231/273.0
ENLPVLIHCVYGKDRTGVLVALILDCIG
.| ||..||. |. |||...|| | .  
sngpvvVHCsaGvgRtgtfialdllldq