Gene OCA-2 in Amphimedon queenslandica

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family OCA
Subfamily OCA
Protein sequence
ID Type Fasta BLAST phosphatome Note
AqueP036_AA protein Get Run
AqueP036_AA_1-141 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_OCA_pd Subfamily OCA 9-142 2.1e-51 164.9 In-house 151-278 (282) alignment
Range on Protein: 9-142
Range on HMM: 151-278/282.0
TVNLSFVIKPAFCGMLKLLLSHEENLPVLIhcvygkDRTGVLVALILDCIGVERETIAmDY-ASSEDGLVSMRNEMYDDLIVNWGMA-EHSCQAKADTML
..  .. .||...|.|.|||..|||||.||      ||.|...|||||...||||||| |. ||||..|||.|||...||..|...| |.|||||.||.|
slveeykdkpvisgllrlllpeeenlpfLi......drlglktaliLdaeeveretia.dflasseiklvslrnevlkdlldndnyavelscqaktdtvl

KVLKEiDKRYGSTSQYLESIGFTLEDQESLKSILLH
|||.. ||.|||||.|||.||||||||||||||||.
kvLrk.dkkygstsiyleyigFtledqeslksilli

0051429 (Phosphotyrosine protein) phosphatases II 16-141 3.2e-27 91.3 In-house 136-272 (272) alignment
Range on Protein: 16-141
Range on HMM: 136-272/272.0
IKPAFCGMLKLLLSheeNLPVLIHCVYGKDRTGVLVALILDCIGVERETIAMDYASSEDGLVSMRNEMYDDLI--------------VNWGMAEHSCQAK
 . |.. .|.|||.   . |||.||  ||||||..|||.|   ||..|||. ||. .. .|   ..|. .                 . . ...   ...
pqeallellellld...ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlyleeaveelraqrpgavqteeqylflyeallellrsllsvr

ADTMLKVLKEIDKRYGSTSQYLESIGFTLEDQESLKSILL
|...| .|..||..|||. .||...|.. |..| |...||
aeyllaaldaideeyGsvegYLrdlglseeelerLrellL

Y_phosphatase3 Tyrosine phosphatase family 17-72 1.2e-17 59.4 Pfam-A 110-163 (164) alignment
Range on Protein: 17-72
Range on HMM: 110-163/164.0
KPAFCGMLKLLLSHEeNlPVLIHCVYGKDRTGVLVALILDCIGVERETIAMDYASS
|.|.  .|..|...| . |||.||  |||||||..||.|. .||..|||| ||. .
kkayrkvlealaeee.g.pvlfHCtaGKDRTGvvaalllsllgvdeetiaaDYllt

0051082 (Phosphotyrosine protein) phosphatases II 18-84 6.9e-13 43.9 In-house 78-143 (151) alignment
Range on Protein: 18-84
Range on HMM: 78-143/151.0
PAFCGMLKLLLShEENLPVLIHCVYGKDRTGVLVALILDCIGVERETIAMDYASSEDGLVSMRNEMY
.|.  .|.|||.  .| |||.||  ||.|||.||||.| . ||  |..  .| ..  |.|   ....
davleflellld.kkngpvlvHCsaGkgRTGtlvalylmllgvsleealeeyrlkrpgvvqpnqqfl

Y_phosphatase3C Tyrosine phosphatase family C-terminal region 100-141 5.6e-12 35.1 Pfam-A 26-68 (68) alignment
Range on Protein: 100-141
Range on HMM: 26-68/68.0
AKADTMLKVLKEIDKRYGSTSQYL-ESIGFTLEDQESLKSILL
......  .|..||.||||  .|| | .|.. ||.| |.. ||
vreeyleaaldtideryGsvegYLeeaLGlseedierLRerlL

0049772 (Phosphotyrosine protein) phosphatases II 18-72 3.5e-11 38.9 In-house 197-253 (314) alignment
Range on Protein: 18-72
Range on HMM: 197-253/314.0
PAFCGMLKLLLSHEENLPVLIHCVYGKDRTG--VLVALILDCIGVERETIAMDYASS
  |  .|......... |||.||  ||.|||  |..|... . ||  |..  |. . 
edfdeflefieeadkggpvlvHCkaGkgRtgtfvvaaylmkllgvsleealedvrlk

0042113 (Phosphotyrosine protein) phosphatases II 9-70 4.7e-10 34.8 In-house 152-219 (245) alignment
Range on Protein: 9-70
Range on HMM: 152-219/245.0
TVNLSFVIKPAFCGMLKLLLSHEENLPVLIHCVYGKDRTGVLVALIL------DCIGVERETIAMDYA
.|  .  .   |. ...  |.  .| |||.||  |..|||...|. |         ||  | .  .. 
gvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleqlekelgvsleeavkelr

0045450 (Phosphotyrosine protein) phosphatases II 5-80 1e-09 34.1 In-house 205-283 (307) alignment
Range on Protein: 5-80
Range on HMM: 205-283/307.0
SQDYTVNLSFVIKPAFCGMLKLLLSHE-ENLPVLIHCVYGKDRTGVLVALILDCIGVERETIA--MDYASSEDGLVSMR
  |..|  || .  .|. ...  |..  .. |||.||  |..|||...|. | . ..|.| .   .|. .  . | ..|
wpdhgvppsfeelldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqR

0043147 (Phosphotyrosine protein) phosphatases II 4-59 1.2e-09 33.6 In-house 72-126 (172) alignment
Range on Protein: 4-59
Range on HMM: 72-126/172.0
SSQDYTVNlSFVIKPAFCGMLKLLLSHEENLPVLIHCVYGKDRTGVLVALILDCIG
.  |..|  .. . . |.  .. ||  ... |||.||..|..|||.|||. | . |
pwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylmllg

0036282 (Phosphotyrosine protein) phosphatases II 18-60 2.1e-09 32.8 In-house 89-131 (174) alignment
Range on Protein: 18-60
Range on HMM: 89-131/174.0
PAFCGMLKLLLSHEENLPVLIHCVYGKDRTGVLVALILDCIGV
  |.  ..  ||. .. |||.||  |..|||.|||. | . | 
lefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgl

0040439 (Phosphotyrosine protein) phosphatases II 6-63 3e-09 32.3 In-house 151-215 (249) alignment
Range on Protein: 6-63
Range on HMM: 151-215/249.0
QDYTVNLSFVIKPAFCGMLKLLLSHE-ENLPVLIHCVYGKDRTGVLVALILD------CIGVERE
 |. |  || .  .|. ...  |..  .. |||.||  |..|||...|. |         ||  |
pdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdle

0039614 (Phosphotyrosine protein) phosphatases II 7-57 8.1e-09 30.8 In-house 195-246 (297) alignment
Range on Protein: 7-57
Range on HMM: 195-246/297.0
DYTVNLSFVIKPAFCGMLKLLLSHE-ENLPVLIHCVYGKDRTGVLVALILDC
|..|  |. .   |. ...  |..  .. |||.||. |..|||...|. | .
dhgvppslellleflelvrealaelpkggpvlVHCsaGvgRtGtfiaaylml

0043336 (Phosphotyrosine protein) phosphatases II 13-66 1e-08 30.5 In-house 191-249 (278) alignment
Range on Protein: 13-66
Range on HMM: 191-249/278.0
SFVIKPAFCGMLKLLLShEENLPVLIHCVYGKDRTGVLVALILD------CIGVERETIA
|. .   |. ...  |.  .| |||.||. |..|||...|| |         ||  | . 
slsllldflkavreale.dsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeav

0049260 (Phosphotyrosine protein) phosphatases II 20-59 1.6e-08 29.9 In-house 77-115 (152) alignment
Range on Protein: 20-59
Range on HMM: 77-115/152.0
FCGMLKLLlSHEENLPVLIHCVYGKDRTGVLVALILDCIG
.. ... |  .... |||.||..|..|||.|||. | . |
lllfiekl.aldkggpvlVHCsaGvgRtgtlvaaylmllg

0040438 (Phosphotyrosine protein) phosphatases II 6-61 1.9e-08 29.4 In-house 183-237 (317) alignment
Range on Protein: 6-61
Range on HMM: 183-237/317.0
QDYTVNLSFVIKPAFCGMLKLLLShEENLPVLIHCVYGKDRTGVLVALILDCIGVE
 |..|  |. .  .|. ...  |. ... |||.||. |..|||...|. | .  .|
pdhgvppspdllldfleavreale.dpggpvlVHCsaGvgRtGtfiaaylmleqle

0048076 (Phosphotyrosine protein) phosphatases II 24-55 2.7e-08 29.2 In-house 71-103 (145) alignment
Range on Protein: 24-55
Range on HMM: 71-103/145.0
LKLLLS-HEENLPVLIHCVYGKDRTGVLVALIL
|... . ..|. |||.||  |..|||.|||. |
lefieealkeggpvlVHCsaGvgRtgtlvaayl

0038934 (Phosphotyrosine protein) phosphatases II 12-55 3.5e-08 28.8 In-house 94-137 (194) alignment
Range on Protein: 12-55
Range on HMM: 94-137/194.0
LSFVIKPAFCGMLKLLLSHEENLPVLIHCVYGKDRTGVLVALIL
 |. |   |. ...  |.  ..  |..||..|. |||.|||  |
PsleillrfldlvdeflnedpggvvaVHCkaGlgRtGtlvaaYL

0048179 (Phosphotyrosine protein) phosphatases II 23-55 3.7e-08 28.7 In-house 72-105 (144) alignment
Range on Protein: 23-55
Range on HMM: 72-105/144.0
MLKLLLSH-EENLPVLIHCVYGKDRTGVLVALIL
.|... .. ||. |||.|| .|..|||.|||. |
flefieealeeggpvlVHCsaGvgRtgtlvaayl

0045098 (Phosphotyrosine protein) phosphatases II 23-60 3.8e-08 28.5 In-house 184-233 (278) alignment
Range on Protein: 23-60
Range on HMM: 184-233/278.0
MLKLLLS------------HEENLPVLIHCVYGKDRTGVLVALILDCIGV
...  |.            .... |||.|| .|..|||.|||. | .  .
firealkllaslllsslllldsggpvlVHCsaGvgRtGtlvaaylmlell

0044763 (Phosphotyrosine protein) phosphatases II 17-55 4.1e-08 28.6 In-house 95-132 (178) alignment
Range on Protein: 17-55
Range on HMM: 95-132/178.0
KPAFCGMLKLLLShEENLPVLIHCVYGKDRTGVLVALIL
 ..|. ... .|. |.. |||.|| .|..|.|.|||. |
flefvefieeald.ekggpvlVHCsaGvgRsgtlvaayl

0037934 (Phosphotyrosine protein) phosphatases II 24-59 5.3e-08 28.2 In-house 162-206 (243) alignment
Range on Protein: 24-59
Range on HMM: 162-206/243.0
LKLLLSH-------EENLPVLIHCVYGKDRTGVLVALILDCI--G
..  ..         .. |||.||. |..|||.|.|. | .   |
vrefieellsllaldsggpvlVHCsaGvgRtGtliaaylmllllg

0041856 (Phosphotyrosine protein) phosphatases II 22-55 7.9e-08 27.6 In-house 100-131 (182) alignment
Range on Protein: 22-55
Range on HMM: 100-131/182.0
GMLKLLLSheENLPVLIHCVYGKDRTGVLVALIL
 ...  |.  |. |||.|| .|..|||.|||. |
dfieevle..eggpvlVHCsaGvgRtgtlvaayl

PTPc_DSPc_SM00012 27-83 9e-08 27.6 In-house 32-89 (105) alignment
Range on Protein: 27-83
Range on HMM: 32-89/105.0
LLSHEE-NLPVLIHCVYGKDRTGVLVALILDCIGVERETIAMDYASSEDGLVSMRNEM
  ...| . ||..||  | .|||..||| . .  .|.||  .|       | ..|. |
nknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgm

0046846 (Phosphotyrosine protein) phosphatases II 23-58 1.7e-07 26.7 In-house 101-134 (176) alignment
Range on Protein: 23-58
Range on HMM: 101-134/176.0
MLKLLLSheENLPVLIHCVYGKDRTGVLVALILDCI
...  |.  |. |||.||. |. |||.|||. | . 
firealk..eggpvlVHCsaGigRtgtlvaayllel

0046845 (Phosphotyrosine protein) phosphatases II 2-68 2.2e-07 26.0 In-house 172-241 (284) alignment
Range on Protein: 2-68
Range on HMM: 172-241/284.0
FTSSQDYTVNLSFVIKPAFCGMLKLLLSH-EENLPVLIHCVYGKDRTGVLVALILDCIGVERETI--AMD
.||  |. |  |. .  .|. ... ||.. . . |...||  |. |||...|| | .  .|.| .   .|
ytswpdhgvppspedlleflrlvrellenlpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvd

Y_phosphatase2 Tyrosine phosphatase family 23-54 2.2e-07 22.8 Pfam-A 82-112 (165) alignment
Range on Protein: 23-54
Range on HMM: 82-112/165.0
MLKLLLShEENLPVLIHCVYGKDRTGVLVALI
.|||||  .|| |||.||  || |||.... .
alkllln.kenypvllhckrGkhrtglvigcl

0036941 (Phosphotyrosine protein) phosphatases II 3-62 2.3e-07 25.9 In-house 176-236 (297) alignment
Range on Protein: 3-62
Range on HMM: 176-236/297.0
TSSQDYTVNLSFVIKPAFCGMLKLLLSHE-ENLPVLIHCVYGKDRTGVLVALILDCIGVER
|.  |. |  |. .  .|. ...  |..  .. |||.||. |. |.|...|. | .  .|.
tgwpdhgvpespaslldfielvrkvlkllpsggpvlVHCsaGvgRsgtfiaadlmlqqled

0051299 (Phosphotyrosine protein) phosphatases II 3-67 2.4e-07 26.0 In-house 190-252 (288) alignment
Range on Protein: 3-67
Range on HMM: 190-252/288.0
TSSQDYTVNLSFVIKPAFCGMLKLLLShEENLPVLIHCVYGKDRTGVLVALILDCIGVEREtIAM
|.  |. |  |.    .|. ...  |.   . ||..||  |..|||...|| | .  .|.|   .
tnwpdhgvpdspellldflrlvrkala.sgggpvvVHCsaGvgRtgtfialdllleqleke.ggv

0050432 (Phosphotyrosine protein) phosphatases II 20-70 3e-07 25.5 In-house 219-268 (308) alignment
Range on Protein: 20-70
Range on HMM: 219-268/308.0
FCGMLKLLLSHEENLPVLIHCVYGKDRTGVLVALILDCIGVEREtIAMDYA
.  .|.|. .. .. |...||  |  |||...|| | .  .|.|   .|. 
lldflelvrkslpggpivVHCsaGvGRtGtfialdllleqleke.ggvdvf

0047943 (Phosphotyrosine protein) phosphatases II 7-63 5.7e-07 24.7 In-house 178-235 (273) alignment
Range on Protein: 7-63
Range on HMM: 178-235/273.0
DYTVNLSFVIKPAFCGMLKLLLSHE-ENLPVLIHCVYGKDRTGVLVALILDCIGVERE
|. |  |. .   |. ...  |..  .| ||..||. |. |||...|| | .  .|.|
dhgvppslesllefielvrkalealpsngpvvVHCsaGvgRtgtfialdllldqleke

IpgD Enterobacterial virulence protein IpgD 29-114 5.1e-06 11.2 Pfam-A 449-532 (559) alignment
Range on Protein: 29-114
Range on HMM: 449-532/559.0
SHEENLPVLIHCVYGKDRTGVLVALILDCIGVERETIAMDYASSEdgLVSMRNEMYDDLIVNWGMAEHSCQAKADTMLKVLKEIDK
..| .      |  ||||||.  | |   |    ||  .   .|   | |  . ... ...| |  | |      .  ||.|..  
ayeidavpawncksGkdrtGmqdaeikreiiskhetgqlsalnsk..ldseekklfskvllnsGnmeisemntGvaGnkvmkklsl