Gene PTEN in Amphimedon queenslandica

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family PTEN
Subfamily PTEN
Protein sequence
ID Type Fasta BLAST phosphatome Note
AqueP041_AA protein Get Run
AqueP041_AA_5-190 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_PTEN_pd Subfamily PTEN 6-185 3.6e-85 279.6 In-house 2-182 (184) alignment
Range on Protein: 6-185
Range on HMM: 2-182/184.0
FRHLVSKRKRRFIADGFDLDMTFIKPNIVAMGFPSEKLEGVYRNKMSDVQRYFDTHYTDHYKVYNLCSERFYDPKKFH-KVTVYPFDDHNPPPFELIQPF
.|..|||.|.||  ||.|||...|..||.|||.|.||||..|||...||.........||||.|||.||| || |||. .|.|||||||||||.||....
lrkivskkkkrfkedgldLDlsyiteniiamgyPaeklealyRnsledvvkflekkhkdhykiynlrserkydskkfdgrvavypfdDhnppplelleei

CEDVDGWLKEDNRNVAVIHCKAGKGRTGVMICSYLLHDRLFDTVKDALQFYGEARTQNAKGVTIPSQRRYVQYYGHLIRNN
.||.. ||.||..||.|.|||||||||||.|..|||. .|... ..||... ||||.|.||||||||||||.|| .|....
vediekwleedkknvvvvHCkaGkGRtGvlivayllkslllekaeealelfaeaRtknkkgvtiPsqrRYveYyeklleee

subfamily_VSP_pd Subfamily VSP 5-189 1.3e-63 208.7 In-house 15-205 (212) alignment
Range on Protein: 5-189
Range on HMM: 15-205/212.0
KFRHLVSKRKRRFIADGFDLDMTFIKPNIVAMGFPSEKLEGVYRNKMSDVQRYFDTHYTDHYKVYNLCSERFYDPKKFH-KVTVYPFDDHNPPPFELIQP
  |.|||. |||.  ||||||.|..   |.|| |||   . .||| .|.| |..|| ..|||||.|||||| ||.| |. .|.    |||| | .| .  
aarrlvsenkrrytqdGfdldltyvteriiamsfpssGkqslyrnpisevarfldtkhrdhykvvnlcseraydekyfnnrvkriliddhnvpkleellv

FCEDVDGWLKEDNRNVAVIHCKAGKGRTGVMICSYLLHDRLFDTVKDALQFYGEARTQNA-----KGVTIPSQRRYVQYYGHLIRNNLQYS
|...|  ||..|..|| .|||| |||||| ..|..||.  .|.| |..|...|| ||...     .||  |||.|||.|. ...    .  
ftkevkewlekdlknvlaihckGGkgrtGtivcalllaseifetakesldyfgerrtdktegekfqGvqtpsqkryvgyleqvktkynrkl

PTEN_1 11-182 2.6e-46 152.9 In-house 7-192 (196) alignment
Range on Protein: 11-182
Range on HMM: 7-192/196.0
SKRKRRFIADGFDLDMTFIKPNIVAMG-FPSEK-----LEGVYRNKMSDVQRYFDTHYTDH-YKVYNLCSERF-----YDPKK--FHKVT--VYPFDDHN
. .|.. . ....||.|.| . |.||| .||..      ||.||. ..||....|. . |. . |.||..|.      ||...   ..|.   .|..||.
rsskknlalptelldltyitsriiamgkapsrpllqeideglyrgslkdvaadldnlkedgitlvvnlseeeelsgrsydleeffksgveylhfpieDhg

PPPFELIQPFCEDVDGWLKEDN-RNVAVIHCKAGKGRTGVMICSYLLHDRLfDTVKDALQFYGEARTQNAKGvtIPSQRRYVQYYGHLI
.|... .. .|.... ||..|. .||...|||||.||.|.....||.. .  .|...||... |.|...|.   .|||.|...|.  | 
apslselfdicksfiewllsdpngnvVlVHCkaGlgRsGtvvaayLmykgk.ltadeAlelvrekRppgapn..spsqerlleyfaell

0036282 (Phosphotyrosine protein) phosphatases II 21-185 4.2e-42 139.1 In-house 7-172 (174) alignment
Range on Protein: 21-185
Range on HMM: 7-172/174.0
GFDLDMTFIKPNIVAMGFPSEKLEGVYRNKMSDVQRYFDTHYTDHYKVYNLCSERFYDPKKF-HKVTVYPFDDHNPPPFELIQPFCEDVDGWLKEDNRNV
 ..||.. | |...|...| . .| ..... ..| .. . .. ..||..|...|. .|.... ...  .|..||..|... .. |.. |. .|.||. ..
aspldlsyitprliagqgplafwemlkelgittvvmlleekelglykcinywpelredlerlgiqylylpwpDhgvpdlsillefvkfveealsedpggp

AVIHCKAGKGRTGVMICSYLLHDRLFDTVKDALQFYGEARTQNAKGVTIPSQRRYVQYYGHLIRNN
 ..||.||.||||.... ||.. .|. .. |||... |.|.|. ..|..|||.|...|.. |....
vlVHCsaGvgRtGtlvaaylmlrglleslvdaldlvrelRlqrpgmvqtpsQyrflyyfekllsgs

subfamily_Tensin_pd Subfamily Tensin 15-198 4.3e-41 133.5 In-house 2-187 (189) alignment
Range on Protein: 15-198
Range on HMM: 2-187/189.0
RRFIADGFDLDMTFIKPNIVAMGFPSEKLEGVYRNKMSDVQRYFDTHYTDHYKVYNLcSERFYDPKKFH-KVTVYPFDDHNPPPFELIQPFCEDVDGWLK
 |.. . .|||.|.|   |.|. ||.| ||  ||... || . ..... |.| |.|| ||. || .|.. ||. . . |.  |..| .   |...| |||
vryveekvdldltyiteriialsfpaegleekyrenlkdvakllkskhndkylvfnl.sekrydisklnkkvldfGWPdllaPsleklcsicksldsWlk

EDNRNVAVIHCKAGKGRTGVMICSYLLHDRLFDTVKDALQFYGEARTQNA--KGVTIPSQRRYVQYYGHLIRNNLQYSPRTILLHAI
.| .||.|.||| ||||.||.. .|. . ..  . . ||. .   |  ..  .|.| |||||||.|.  |. .... . . ..|| .
adpqnvvvvhckGgkgrigvvvsaymkyskisasadaaldrfamkrflddklsgetqPsqrryveyfsglLsgkiklnssplflhyv

subfamily_Auxilin_pd Subfamily Auxilin 23-184 6.6e-40 129.5 In-house 8-166 (166) alignment
Range on Protein: 23-184
Range on HMM: 8-166/166.0
DLDMTFIKPNIVAMGFPSEKLEGVYRNKMSDVQRYFDTHYTDHYKVYNLcSERFYDPKKFH-KVTVYPFDDHNPPPFELIQPFCEDVDGWLKEDNRNVAV
|||...|   |. | ||.|..|  |.|.. ||. . .......|.|||| |.| |...|.. .|. . .  .. |. | .   | ... |||.|..|| |
dlDisyitsriivmsfPaegvestyknniddvrsfLesrhpekylvynl.sqrtyrtaklssrvveagwparraPnLeslvevcrnlyswlkkdpknvvv

IHCKAGKGRTGVMICSYLLHDRLFDTVKDALQFYGEARTQNAkgvTIPSQRRYVQYYGHLIRN
.||| |.  ..|.....|.. ||. ....|....   |.        ||..||..| ..|...
vhckDGraasavlvsallvfcrllsepesavrlfsvkrlpig...lspsekryleyladllae

0038934 (Phosphotyrosine protein) phosphatases II 28-178 8.3e-40 131.9 In-house 15-166 (194) alignment
Range on Protein: 28-178
Range on HMM: 15-166/194.0
FIKPNIVAMGFPSEK-----LEGVYRNKMSDVQRYFDTHYTDHYKVYNLC-SERFYDPKKFHKV----TVYPFDD-HNPPPFELIQPFCEDVDGWLKEDN
.|.....|...|...     .|..||. ..|. ||..... ....|..|. .||.|||..|.|.      .|| | ...|..|... |.. || .|.||.
iitgrfiafkvPlsgsldkyieelyrfspedlvrylkllnvklglvidltnteryYdpeefekagieylklpfpddgtvPsleillrfldlvdeflnedp

RNVAVIHCKAGKGRTGVMICSYLLHDRLFdTVKDALQFYGEARtqnakgvtiPSQRRYVQYY
 .| ..|||||.||||.....||.. . . ....|.... |.|         |.. ....|.
ggvvaVHCkaGlgRtGtlvaaYLiyrlgm.saeeAialfrekR.........pgaipnqdyl

PTEN_C2 C2 domain of PTEN tumour-suppressor protein 188-346 2.4e-33 106.2 Pfam-A 1-133 (134) alignment
Range on Protein: 188-346
Range on HMM: 1-133/134.0
YSPRTILLHAIRLEGIPNF-SGGTCAPFFIVRKHKVVL-YTSKVYESIRRT-DAFAELMLTKPIPLCDDIKVEFYHNPrfgSKASYTEKMFLFWFNTFFV
| |... |..|.||||||| ..|.| |.. | ..|... .... |.. ... .  . . . ...|...|..|||.|.    || .. ||.| .||||.|.
ynpkrlelksiilegiPnfktrggckpkvkvyngkkkvfkelasykdsterraktfivkepnrlpveGDvlveflhkd...sklpkkekifrvwFNTsFi

DWhvmqqeaqnamatnslsvswlytasHFRVVILPKNEIDKANKDKkHKQYPCNFKVHMVLS
.                             |..|||||.|||.||| .|... ||||..|..
ek.........................nqnvltlpkneLDkalkdk.dkkfsknfkvelvfe

0046846 (Phosphotyrosine protein) phosphatases II 16-184 7.3e-33 109.2 In-house 2-174 (176) alignment
Range on Protein: 16-184
Range on HMM: 2-174/176.0
RFIADGFDLDMTFIKPNIVAMGFPSEKLEGVYRNKMSDVQRYFDThytDHYKVYNLCSER-------FYDPKK----FHKVTVYPFDDHNPPPFELIQPF
|.  .|.|||...| .|......|  . ....|. .........    ... | ||..|.       .....      ... ..|..||..|..||.. .
rlrllgldldldyinanlilgsrpiatqgplprtladflemlkel...gitavvnlteevelgrlkcpnywpeleklgiqylhlpwpDhgvpdlelllel

CEDVDGWLKEDnrNVAVIHCKAGKGRTGVMICSYLLHDRLFDTVKDALQFYGEARTQnaKGVTIPSQRRYVQYYGHLIRN
.| .. .|||.  .. ..||.||.||||.... |||. . . .| .||... | |    . |. |.|.|..... .|...
lefirealkeg..gpvlVHCsaGigRtgtlvaayllelekglsveealalvreqRpl..gavqtpeQyrflyefellllk

0043147 (Phosphotyrosine protein) phosphatases II 19-183 6.7e-32 106.0 In-house 8-161 (172) alignment
Range on Protein: 19-183
Range on HMM: 8-161/172.0
ADGFDLDMTFIKPNIVAMGFPseklegvYRNKMSDVQRYFDTHYTDHykVYNLCsERFYDPKKFH----KVTVYPFDDHNPPPFELIQPFCEDVDGWLKE
 . ..||...| ....|. .|       .|| ..|. |.. ..  .|  ..||. |..|||....    ..  .|..||..|..||.. |.| .| .| .
inasyldlyyipdrfiatqgp.......lrntladfwrmlkelgith..ivnlt.ellydpellerlgiqylylpwpDhgvpllellleflefidellal

DNRNVAVIHCKAGKGRTGVMICSYLLHdrLFDTVKDALQFYGEARtqnAKGVTIPSQRRYVQYYGHLIR
.. .. ..||.||.||||.... ||..  |  .. .|.... |.|    ..|..|||.|...|. .|..
spggpvlVHCsaGvgRtgtlvaaylml..lglsleeavalvrekR...pgavqnpsqyrflyyfeklll

0041856 (Phosphotyrosine protein) phosphatases II 13-181 1.8e-31 104.6 In-house 6-169 (182) alignment
Range on Protein: 13-181
Range on HMM: 6-169/182.0
RKRRFIADGFDLDMTFIKPNIVAMGFPSEKLEGVYRNKMSDVQRYFDTHYTDHYK-VYNLCsERFYDPKKFH----KVTVYPFDDHNPPPFELIQPFCED
| . ..   ...|...| .|......|. . .  ... .|.| ..... .  ... . ||. |. |.|....    ..  .|..||..|... .  |.|.
rysdilpydhsrdldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt.eelywpellerlgiqylylpwpDhgvpdldelldfiee

VDGwlkedNRNVAVIHCKAGKGRTGVMICSYLLHDRlFDTVKDALQFYGEARtqnAKGVTIPSQRRYVQYYGHL
|       . .. ..||.||.||||.... ||.. .   .. .|.... ..|    ..|..|.| ...|.. ..
vle.....eggpvlVHCsaGvgRtgtlvaaylmkkl.gvsleeavklvrsrR...pgmvitpnqyfflqlalle

0039614 (Phosphotyrosine protein) phosphatases II 6-179 1.1e-30 102.6 In-house 51-285 (297) alignment
Range on Protein: 6-179
Range on HMM: 51-285/297.0
FRHLVSKRKRRFI--------------ADGFDLDMTFI-----------KPNIVAMGFPSEKL-----EGVYRNKMSDVQ--------------------
... ..| |.|..               ||.|||...|           .....|...|...      . |.... . .                     
allpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIatqgPlpetvedFwrmvweqgvtvivmLtklvelgrkcaqywpeeg

--------RYFDTHYTDHYKVYNLCSERfYDPKKFHKVTVY-PFDDHNPP-PFELIQPFCEDVDGWLKED-NRNVAVIHCKAGKGRTGVMICSYLLH---
        .. .... |.|.|..|. .. ... .....  | .. ||..|  .||.. |.| |. .|.|. . .. ..||.||.||||..|. ||..   
gtygdftvtllkvehldgytvrtlevtn.ngesrtvthfqytgwpdhgvppslellleflelvrealaelpkggpvlVHCsaGvgRtGtfiaaylmleql

-DRLFDTVKDALQFYGEARtqnAKGVTIPSQRRYVQYYG
  .   .|..|.... |.|    ..|..||| |..... 
ekeggvdvleavkelreqR...pgavqtpsqyrflydal

0049260 (Phosphotyrosine protein) phosphatases II 34-182 1.9e-30 100.9 In-house 5-149 (152) alignment
Range on Protein: 34-182
Range on HMM: 5-149/152.0
VAMGFPSEKLEGVYRNKMSDVQRYFDTHYTDHYKVYNLCSERFYDPKK-FHKVTVYPFDDHNPPPFELIQPFCEDVDGWLKEDNRNVAVIHCKAGKGRTG
.||.|.    .|...| ..|. |.. ..  ... ... ..|. ..  .   ..  .|..||..|... . .|. ... .|..|. .. ..||.||.||||
yampfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyiqylhlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtg

VMICSYLLHdrlfdTVKDALQFYGEARTQNAKGVTIPSQRRYVQYYGHLI
.... ||..        ......   |... ..|. |.|.|.....  |.
tlvaaylml.....lgvsleeavalvrekRpgavpnpgqlrflyefekll

0037934 (Phosphotyrosine protein) phosphatases II 6-179 7.1e-30 99.8 In-house 5-238 (243) alignment
Range on Protein: 6-179
Range on HMM: 5-238/243.0
FRHLVSKRKRRFI--------------ADGFDLDMTFIKPNIVAMGFPSEK---------LEGVYRNKMSDVQ---------------------------
....... |.|.                | ...... . |.. |...| ..         .. ..... . .                            
allpenlsknrysdilpydhsrvklegsdyinanliyvtprliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywpgevtygdft

-RYFDTHYTDHYKVYNLCSER---FYDPKKFHKVTVYPFDDHNPPP-FELIQPFCEDVDGWLKE-------DNRNVAVIHCKAGKGRTGVMICSYLLHDR
 .. .....|.|.|..|. |.    . ..  ...  .|. ||..|. .| .. |...|  ...|       |. .. ..||.||.||||..|. ||....
vtllseehlddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtliaaylmlll

LFDTVKDALQFYGEARTQnaKGVTIPSQRRYVQYYG
|  .. .|.... | | .  |.|..|||.|..... 
lgvdleeavkllreqRpg..kavqtpsqyrflyeal

0045450 (Phosphotyrosine protein) phosphatases II 6-178 5.8e-29 97.2 In-house 50-299 (307) alignment
Range on Protein: 6-178
Range on HMM: 50-299/307.0
FRHLVSKRKRRFIA-------------------------------------DGFDLDMTFI----------------------------------KPNIV
......| |.|.                                       ||.||...||                                  . .. 
allpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydlkrkfIatqgPlpetvedFwrmlweqgvtvivmltelvelgrekc

AMGFPSEKLEGVYRNkmsDVQRYFDTHYTDHYKVYNLCSERFYDPKKFHKVTVYPF---DDHNPPP-FELIQPFCEDVDGWLKED-NRNVAVIHCKAGKG
|. .|.|. | .|.|   .. .. .... |.|.|..|. ..    .. ..||....    ||. || || .  |.| |. .|.|. . .. ..||.||.|
aqywPdegeeltygn...ftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfeelldfieevrkaleelpkggpvlVHCsaGvg

RTGVMICSYLLHDRLF-------DTVKDALQFYGEARtqnAKGVTIPSQRRYVQYY
|||..|. ||. ..|         .. .|.... | |    ..|. |.| |.....
RtGtfiaaylmlrqlekegtlldvdlleavkllreqR...pgavqnpeqyrflyea

0042113 (Phosphotyrosine protein) phosphatases II 6-178 1e-27 92.5 In-house 4-238 (245) alignment
Range on Protein: 6-178
Range on HMM: 4-238/245.0
FRHLVSKRKRRF-------------IADGFDLDMTFI----------KPNIVAMGFPSEKLEG-----VYRNKMSDVQ----------------------
......| |.|.               ||.||| ..|          .|.. |...|...  .     ..... . .                       
allpenkdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywplges

--------RYFDTHYTDHYKVYNLCSERFYDP--KKFHKVTVYPFDDHNPPP-FELIQPFCEDVDGWLKEDNRNVAVIHCKAGKGRTGVMICSYLLH---
        .. .... |.|.|..|. .. .|.  .. . .  .|..||..|.  ||.. |.| |. .|.||. .. ..||.||.||||..|. ||..   
ltygdftvtllseehlddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleql

-DRLFDTVKDALQFYGEARtqnAKGVTIPSQRRYVQYY
  .|  .. .|.... . |    . |..||| |.....
ekelgvsleeavkelrsqR...pgavqtpsqyrflyea

0045098 (Phosphotyrosine protein) phosphatases II 21-183 1.2e-27 92.4 In-house 4-272 (278) alignment
Range on Protein: 21-183
Range on HMM: 4-272/278.0
GFDLDMTFIKPNIVAMGFPSEKLEGVYRNKMS--------------------------------------------------------------------
...||.. .  .....|.||| ....|.. ..                                                                    
lasldlllefefllllgipseitpalylgnldknRykdilpydhsrVkdYINAsyidgypkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgr

-----------------------DVQRYfDTHYTDHYKVYNLCSERFYDPKKFHKVTVY-PFDDHNPPPFE---LIQPFCEDVDGWLK------------
                       ..... |. .. ...|.||..|| .... . ..  | |..||..|...    .. ..| .. .||            
ekcaqywpeggsltygdftvtllseevl.ddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslll

EDNRNVAVIHCKAGKGRTGVMICSYLLHDRLfDTVKDALQFYGEARTQNAK-GVTIPSQRRYVQYYGHLIR
.|. .. ..||.||.||||.... ||. ..| . . |.|. . | |.|     |....| |.. ..  ...
ldsggpvlVHCsaGvgRtGtlvaaylmlell.eggvdlleavkelrsqRpglavqnleqyrflyefllell

0043336 (Phosphotyrosine protein) phosphatases II 10-178 1.6e-27 92.1 In-house 44-272 (278) alignment
Range on Protein: 10-178
Range on HMM: 44-272/278.0
VSKRKRRF-------------IADGFDLDMTFI----------KPNIVAMGFPSEKLEGVYRNKMSDVQ-------------------------------
 .| |.|.               .|.|||...|          .....|...|... .. ... . . .                               
enkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpetvedFwrmvwelgvttivmLtelvelgrvkcaqYwpggsltygd

---RYFDTHYTDHYKVYNLCSERFYDPKKFHK--VTVYPFDDHNPP-PFELIQPFCEDVDGWLKeDNRNVAVIHCKAGKGRTGVMICSYLLH----DRLF
   .. .... |.|.|..|. .. .|.....   .  ... ||. | ...|.. |...|. .|. |. .. ..||.||.||||..|. |||.    ....
ftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldflkavreale.dsngpvlVHCsaGvgRTGtfialyllleqlekegg

DTVKDALQFYGEARtqnAKGVTIPSQRRYVQYY
 .. .|.... | |   .. |. ||| |.. ..
vdleeavkelreqR...pgavqtpsqyrflyea

0046845 (Phosphotyrosine protein) phosphatases II 19-177 4.6e-26 87.3 In-house 65-268 (284) alignment
Range on Protein: 19-177
Range on HMM: 65-268/284.0
ADGFDLDMTFIKPNIVAMGFPSEK-----------------------------LEGVYRNKMSDVQRY-------FDTHYTDHYKVYNLCSERFYDPKKF
 ||.|||.| ||....|. .| ..                                 |.. ...|..|        .... |.|.|..|. ..   ... 
vdgydldltyikkkfIatqgPlpntvedFwrmvweqnvrvIVmltelvengrekcaqYwplegevltygdftvtllseevkddytvrtleltnlgytges

HKVTVYPF---DDHNPPP-FELIQPFCEDVDGWLKE-DNRNVAVIHCKAGKGRTGVMICSYLLHDRLFDT----VKDALQFYGEARTQNAKGVTIPSQRR
..||.. .    ||. || .| .. |...|. .|.. .. .. |.||.||.||||..|. .||...|  .    . |.|. .   |.|    |. ..| |
rtvthfhytswpdhgvppspedlleflrlvrellenlpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyr

YVQY
.| .
fvye

0040439 (Phosphotyrosine protein) phosphatases II 8-178 7.2e-26 86.7 In-house 8-241 (249) alignment
Range on Protein: 8-178
Range on HMM: 8-241/249.0
HLVSKRKRRFI---------------ADGFD--------LDMTFIKPNIVAMGFPSEKLEGVYRNKMSDVQ-----------------------------
....| |.|.                 ..|.        .|.. ||....|...| ..  . ... . . .                             
lpenkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywplggsle

------RYFDTHYTDHYKVYNLCSERFYDPKKfHKVTVYPF---DDHNPP-PFELIQPFCEDVDGWLKED-NRNVAVIHCKAGKGRTGVMICSYLLHDRL
      ....... |.|.|..|. .. ||... ..|.....    ||. |  || .  |.| |. .|.|. . .. ..||.||.||||..|. ||....|
ygdftvtllsvevkddytvrtleltnlydges.rtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylmleql

-FDTVKDALQFYGEARTQNAKGVTIPSQRRYVQYY
      |... . . |.|  ..|. |.| |.....
ekelgvdleeavkllrsqRpgavqnpeqyrflyea

0048179 (Phosphotyrosine protein) phosphatases II 38-180 1.3e-25 85.2 In-house 3-142 (144) alignment
Range on Protein: 38-180
Range on HMM: 3-142/144.0
FPSEKLEGVYRNKMSDVQRYFDTHYTDHYKVYNLCSERFYDPKKFH--KVTVYPFDDHNPPPF-ELIQPFCEDVDGWLKEDnrNVAVIHCKAGKGRTGVM
.||| |.|.|.. . .....   .  ... |.||..|. ..  ...  ..  .|..||..|.. ||.. |.| .. .|.|.  .. ..||.||.||||..
npseilpglylgslptaldlellkklgittvinlteeyepefleregiqylhlpwpDhgvpdllellleflefieealeeg..gpvlVHCsaGvgRtgtl

ICSYLLHdRLFDTVKDALQFYgeaRTQNAKGVTIPSQRRYVQYYGH
.. ||.. .|  ....||...   |...  .|. |.|.|....|..
vaaylmk.klglsleealalv...rsrrpgavpnpgqlrfLleyek

0048076 (Phosphotyrosine protein) phosphatases II 38-180 1.6e-25 84.9 In-house 3-140 (145) alignment
Range on Protein: 38-180
Range on HMM: 3-140/145.0
FPSEKLEGVYRNKMSDVQRYFDTHYTDHYKVYNLCSERFYDPKKFHKVTVYPFDDHNPPPF-ELIQPFCEDVDGWLKEDnrNVAVIHCKAGKGRTGVMIC
.||| |.|.|.. . .....   .  ... |.||.||. .  ..  ..  .|..||..|.. ||.. |.| .. .|||.  .. ..||.||.||||....
wpseilpglylgslptaldlellkdlgittvlnltselellerlgiqylylpwpDhgvpdllellleflefieealkeg..gpvlVHCsaGvgRtgtlva

SYLLHDRLfDTVKDALQFYGEARtqnAKGVTIPSQRRYVQYYGH
 ||.. .   .. .||... ..|    ..|. |.|.|..... .
aylmlllg.vsleealelvrsqr...pgavpnpgqlrflyefel

0051082 (Phosphotyrosine protein) phosphatases II 24-178 2.9e-25 84.0 In-house 6-147 (151) alignment
Range on Protein: 24-178
Range on HMM: 6-147/151.0
LDMTFIKPNIVAMGFPSEklegvyrnkmsDVQRYFdtHYTDHYKVYNLCS--ERFYDPKKFHK----VTVYPFDDHNPPPFELIQPFCEDVDGWLKEDNR
...... ... ..|.|..           |. ...  .  ... ..||.|  || |.|. ...    |. .|..|. .|...|..... ..  .| ... 
infsyvtgglyrsggpla...........dflell..kelgiktivnlrseeergycpeylpelgievlhipildwpdpglplsfdavleflellldkkn

NVAVIHCKAGKGRTGVMICSYLLHdrLFDTVKDALQFYGEARTqnakGVTIPSQRRYVQYY
.. ..||.|||||||.... ||..  |  .. .||..| . |.    ||..|.| ...|..
gpvlvHCsaGkgRTGtlvalylml..lgvsleealeeyrlkrp....gvvqpnqqflfqlf

0040438 (Phosphotyrosine protein) phosphatases II 7-178 3.9e-25 84.2 In-house 39-271 (317) alignment
Range on Protein: 7-178
Range on HMM: 39-271/317.0
RHLVSKRKRRF-------------IADGFDLDMTFI----------KPNIVAMGFPSEK-----LEGVYRNKMSDVQ-----------------------
.....| |.|.               .|.||| ..|          |....|...| ..     .. |.... . .                        
elpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPlpntvedFwrmvweqgvtvivmLteleelgrekcaqYwplgetl

-------RYFDTHYTDHYKVYNLCSERF-YDPKKFHKVTVYPF-DDHNPPP-FELIQPFCEDVDGWLKeDNRNVAVIHCKAGKGRTGVMICSYLLH----
       .. .... .......|. |    ... . ..  |.. .||..|| ..|.. |.| |. .|. |. .. ..||.||.||||..|. ||..    
tygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavreale.dpggpvlVHCsaGvgRtGtfiaaylmleqle

DRLFDTVKDALQFYGEARtqnAKGVTIPSQRRYVQYY
 . . .|..|.... |.|   ...|. |.| |.. ..
keggvdveeavkelreqR...pgavqtpeqyrflyda

0049772 (Phosphotyrosine protein) phosphatases II 39-179 4e-25 84.6 In-house 155-274 (314) alignment
Range on Protein: 39-179
Range on HMM: 155-274/314.0
PseklegvyrnkmsdvqRYFDTHYTDHYKvynlcsERFYDPKKFHKV-TVY---PFDDHNPPPFELIQPFCEDVDGWlkeDNRNVAVIHCKAGKGRTGV-
.                 . . .. ...|      |. |||..| .    |   |..|...|..| .. |.| .. .   |. .. ..||||||||||. 
g................neptaadlellk......eelydpelferlgikylripvpDgsaplledfdeflefieea...dkggpvlvHCkaGkgRtgtf

MICSYLLHDRLFdTVKDALQFYGEARTQNAKGVTIPSQRRYVQYYG
... ||.. . . ....||... ..|. | . ..|.....|.... 
vvaaylmkllgv.sleealedvrlkRpinpnpgfieqleqyefile

0044763 (Phosphotyrosine protein) phosphatases II 9-185 2.7e-23 78.0 In-house 6-173 (178) alignment
Range on Protein: 9-185
Range on HMM: 6-173/178.0
LVSKRKRRFIADGFDLDMTFIKPNIVAMGFPSeklegvyrnkMSDVQRYFDTHYTdHykVYNLCSE--------RFYDPKKF-HKVTVYPFDDHNPPP-F
.|.  ... .  .. .....| |.. ....|.           .|.. . . . | |  . ||..|          |.|...  ..  .|..||..|. .
rvllsnleglersdyinaseilpglylgslpp..........addlellkelgit.h..ivnlteelelgflkcdpywpeeagiqylhipipDhgvpdll

ELIQPFCEDVDGWLKEDNRNVAViHCKAGKGRTGVMICSYLLHDRLFdTVKDALQFYGEARtqnAkGVTIPSQRRYVQYYGHLIRNN
| .. |.| .. .|.|....|.| ||.||.||.|.... ||.. . . .. .|.... |.|     .|. |.|.|.....   ....
ehflefvefieealdekggpvlV.HCsaGvgRsgtlvaaylmkklgl.sleeaielvrerR...p.ivpnpgqlrqLyefelrllke

0051299 (Phosphotyrosine protein) phosphatases II 58-177 2.8e-22 75.0 In-house 154-280 (288) alignment
Range on Protein: 58-177
Range on HMM: 154-280/288.0
FDTHYTDHYKVYNLCSERFY---DPKKFHKVTVYPFD---DHNPPP-FELIQPFCEDVDGWLKeDNRNVAVIHCKAGKGRTGVMICSYLLHDRL-FDTVK
 ...  |.|.|..|. ..      ... ..||.. .    ||. |. .||.  |...|. .|. .. .. |.||.||.||||..|. .||...| .  . 
lseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdspellldflrlvrkala.sgggpvvVHCsaGvgRtgtfialdllleqlekeggv

DALQFYGEARTQNAKGVTIPSQRRYVQY
|.|...   |.|    |. |.| |.| .
dvleavkrlreqRpgmvqtpeqyrfvye

0047943 (Phosphotyrosine protein) phosphatases II 58-177 3.4e-21 71.3 In-house 142-266 (273) alignment
Range on Protein: 58-177
Range on HMM: 142-266/273.0
FDTHYTDHYKVYNLCSERFYDPKkFHKVTVYPFD---DHNPP-PFELIQPFCEDVDGWLKED-NRNVAVIHCKAGKGRTGVMICSYLLHDRL-FDTVKDA
 .... |.|.|..|. ..  ...  ..||.. .    ||. |  .| .  |.|.|. .|... . .. |.||.||.||||..|. .||.|.|      |.
lseetkddytvrtleltnlgtge.srtvthfhytgwpdhgvppslesllefielvrkalealpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdv

LQFYGEARTQNAKGVTIPSQRRYVQY
|. .   |.|   .|. |.|.|.. .
leavkllrsqRpgmvqtpeqyrflye

0036941 (Phosphotyrosine protein) phosphatases II 21-178 2.4e-19 65.2 In-house 73-272 (297) alignment
Range on Protein: 21-178
Range on HMM: 73-272/297.0
GFDLDMTFIK---------------------PNIVAMG-------------FPSEKLEGVYRNKMSDVQRYFDTHYTDHYKVYNLCSERFyDPKKFHKVT
|.||...||                      . || .              .|.|. | .. ....   . ..... |.|....|. .   . .. ..||
gydlkrkfIatqgPlpntvedFWrmvweqnvtvIvmltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdt.gngesrtvt

VYPF---DDHNPPP-FELIQPFCEDVDGWLKED-NRNVAVIHCKAGKGRTGVMICSYLLHDRLF----DTVKDALQFYGEARTQNAKGVTIPSQRRYVQY
.. .   .||..|. .. .  |.| |. .||.  . .. ..||.||.||.|..|. .|....|         | |... . |.| .  |. ..| |.. .
hfhytgwpdhgvpespaslldfielvrkvlkllpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflye

Y
.
a

0050432 (Phosphotyrosine protein) phosphatases II 56-177 1.4e-17 59.4 In-house 152-293 (308) alignment
Range on Protein: 56-177
Range on HMM: 152-293/308.0
RYF-------------------DTHYTDHYKVYNLCSERFYDPkKFHKVTVYPF---DDHNPPP-FELIQPFCEDVDGWLkedNRNVAVIHCKAGKGRTG
.|.                   ...  |.|.|..|. .   |. . ..||.. .    ||. || .| .  |.| |. .|   . .. |.||.|| ||||
qYwplelgggsleygkftvtllseevlddytvrtleltnlgdg.esrtvthfhytnWpdhgvPpspeilldflelvrksl...pggpivVHCsaGvGRtG

VMICSYLLHDRL-FDTVKDALQFYGEARTQNAKGVTIPSQRRYVQY
..|. .||...|  .   |... .   |.| .  |. |.| ... .
tfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylflyr

0051429 (Phosphotyrosine protein) phosphatases II 39-190 7.4e-12 41.0 In-house 76-232 (272) alignment
Range on Protein: 39-190
Range on HMM: 76-232/272.0
PSEKLEGVYRNKMSDVQRYFDTHYTDHYKVYNLCSERFYDPKKFHKVTVYPFDDHNPPPF--ELIQPFCEDVDGwlkednRNVAVIHCKAGKGRTGVMIC
| .  .    . .  . ... ......| ...|. .. ..... ..|... . |    .   | .  . | .         .  ..||.|||.|||....
pilddsaptilygalrvtllseellldyilrellltlllsagearevmhlhytdwpdhgvpqeallellellld......ggpvlvHCsaGkdRTGtvva

SYLLHDRLF-DTVKD--------ALQFYGEARTQNAKGVTIPSQRRYVQYYGHLIRNNLQYSP
 .||  ..  .|. |        ..... | | | .. |  . |..... .   . ..|. ..
llllllgvsletivddYlltnlyleeaveelraqrpgavqteeqylflyeallellrsllsvr

PTPc_DSPc_SM00012 90-171 1.5e-11 39.8 In-house 10-95 (105) alignment
Range on Protein: 90-171
Range on HMM: 10-95/105.0
FDDHN-PPPFELIQPFCEDVDGWLKEDN-RNVAVIHCKAGKGRTGVMICSYLLHDRLFDT--VKDALQFYGEARTQNAKGVTIPSQ
  ||. | . . |  ....|. . .. . ..  |.||.|| ||||.... ..|...| ..    | .|.  | |.| .. |.   |
wpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeq

subfamily_DSP11_pd Subfamily DSP11 73-160 3e-11 37.5 In-house 66-158 (178) alignment
Range on Protein: 73-160
Range on HMM: 66-158/178.0
SERFYDPKKFHKVTVY----PFDDHNPPPFELIQPFCEDVDGWL--KEDNRNVAVIHCKAGKGRTGVMICSYLLHDRLFDTvKDALQFYGEART
 .|.|..|.... .|         |. |  ||.. |.| |. .|  ..|| ..  .||  |  ||| .|| ||..   ... .||.. . ||| 
tdryykkkeltdegvkylklncpGhevpkeelvkkfkeavkefleknkdndkligvhCthGvnrtGyliCrylidvegyep.edaieafeearG

subfamily_RNGTT_pd Subfamily RNGTT 54-161 3.7e-11 37.0 In-house 44-156 (189) alignment
Range on Protein: 54-161
Range on HMM: 44-156/189.0
VQRYFDTHYTDHYKVYNLCS-ERFYDPKKFHK-----VTVYPFDDHNPPPFELIQPFCEDVDGWLKEDNRNVAVIHCKAGKGRTGVMICSYLLHDRLFDt
.  |..|. .    | .|   .|.|| ....|     | .      . |  | .. | . |. . |.  ..|  .||. |  ||| .|.|||.. . .. 
llsylktlkvklglvidltntsryYdkeelekegikyvklqcagkgeaPeaeqvkefiklveeffkknpeevigvhCthGfnRtGFlivsyLvekedws.

VKDALQFYGEARTQ
|..|.. . .|| .
veaavalFakaRpp

subfamily_PRL_pd Subfamily PRL 71-160 1.2e-09 32.4 In-house 40-131 (151) alignment
Range on Protein: 71-160
Range on HMM: 40-131/151.0
LCSERFYDPKKFH----KVTVYPFDDHNPPPFELIQPFCEDVDGWLKEDNRNVAVIHCKAGKGRTGVMICSYLLHDRLfdTVKDALQFYGEART
 . |  || .|..    .|. ..||| ..|| |... . | .    ||.. ..  .|| || ||. |...  |. . .  . .||..|  | | 
rvceptydteklekegievldlafddGavPpeevveeWlellkekfkeepkstvavhcvaGlGraPvlvalalieaGm..kyedavefirekrr

subfamily_PTPDC1_pd Subfamily PTPDC1 86-174 2e-09 32.2 In-house 86-167 (182) alignment
Range on Protein: 86-174
Range on HMM: 86-167/182.0
TVYPFDDHNPPPFELIQPFCEDVDGWLKEDnrNVAViHCKAGKGRTGVMICSYLLHDRLFDTvKDALQFYgeaRTQNAKGVTIPSQRRY
  ....|.. .. | |      |.  |.|.  .||| || ||.|||||.|..||.. . ... ..|...    | . .| .   .| . 
ynfgwkDygvasleriLdivkvvafalqeg..kvav.hChaGlGrtGvliacylvyakrlta.ekaiklv...rskrpksiqtreqvel

0048567 (Phosphotyrosine protein) phosphatases II 75-178 2.4e-09 31.8 In-house 26-134 (157) alignment
Range on Protein: 75-178
Range on HMM: 26-134/157.0
RFYDPKKFHK----VTVYPFDDHNPPPFELIQPFCEDVDGWLK--EDNRNVAVIHCKAGK---GRTGVMICSYLLHDRLFdtvkDALQFYGEARTQNAKG
..|... |.     | . .| |. |..  ..  |.  .. .||  | .... ..|||||    |||...|..||.    |    .. ....  |  . . 
slynalyFsiddglvyedfffdfGPlnlailyrFilklnkflkilelagkaiavhckaglkkrgrtatLigcYlilhlgf....tpeeaiaplrivrpgs

VTIPSQRRYVQYY
|  . .  .. .|
vpfrdasyllsly

subfamily_CDC14_pd Subfamily CDC14 25-145 2.8e-09 31.3 In-house 171-291 (328) alignment
Range on Protein: 25-145
Range on HMM: 171-291/328.0
DMTFIKPN-IVAMGFPSEKLEGVYRNKMSDVQRYFDTHYTDHYKVYNLCSERFYDPKKFHKVTVY----PFDDHNPPPFELIQPFCEDVDGWlkednRNV
|...| |. ..|.  | .| .   . ..   .....   . . .      .. || ||| .  .      | |   |. .... | | ..       .  
DfnwivPdkflalagPhnkskledgyplhaPeklleyfrknnvttvvrLnkklYdakkftdaGfdhkDlffiDGstPsdaivkkfleiaeka.....eGa

AVIHCKAGKGRTGVMICSYLLHDRLF
...||||| |||| .| .||...  |
iavhCkaGLGrtGtLiacylmkhyrf

DSPc Dual specificity phosphatase, catalytic domain 72-162 3.7e-09 31.6 Pfam-A 29-117 (133) alignment
Range on Protein: 72-162
Range on HMM: 29-117/133.0
CSE-RFYDPKKFHKVTVYPFDDHNPPPFELIQPFCEDVDgWLKEDNRNVAViHCKAGKGRTGVMICSYLLHDRLFdTVKDALQFYGEARTQN
... ... ....... .   |...    . ..   | ..  .......|.| ||.||  |.. .|. ||.  . . ....|..|  | | . 
vpnnnaikkseieylripvedetetkiskeleeavefie.kaeqkgkkvlV.HCqaGisRSatliiaYlmktknl.slneAyefvkerrski

DSPc Dual specificity phosphatase, catalytic domain 72-162 3.7e-09 31.6 In-house 29-117 (133) alignment
Range on Protein: 72-162
Range on HMM: 29-117/133.0
CSE-RFYDPKKFHKVTVYPFDDHNPPPFELIQPFCEDVDgWLKEDNRNVAViHCKAGKGRTGVMICSYLLHDRLFdTVKDALQFYGEARTQN
... ... ....... .   |...    . ..   | ..  .......|.| ||.||  |.. .|. ||.  . . ....|..|  | | . 
vpnnnaikkseieylripvedetetkiskeleeavefie.kaeqkgkkvlV.HCqaGisRSatliiaYlmktknl.slneAyefvkerrski

subfamily_DSP23_pd Subfamily DSP23 90-177 3.6e-08 28.2 In-house 59-140 (148) alignment
Range on Protein: 90-177
Range on HMM: 59-140/148.0
FDDHNPPPFELIQPFCEDVDGwLKEDNRNVAvIHCKAGKGRTGVMICSYLLHDRLFDTvKDALqfyGEARTQNAKGVTIPSQRRYVQY
 ||. ||  | .. | . |.   .| |  |. .||  |.|||| |.  ||.. | . .  .|.    | | .    |    | . |. 
iddyhppaleqvvefvrvvee.aeekneavs.vhcllgrgrtgtmlacylvkerklaa.aeai...aevrrlrpgsvetveqeklvrd

Y_phosphatase Protein-tyrosine phosphatase 60-171 1.6e-07 26.4 Pfam-A 115-225 (235) alignment
Range on Protein: 60-171
Range on HMM: 115-225/235.0
THYTDHYKVYNLCSERfyDPKKFHKVTVYPFDDHNPP-PFELIQPFCEDVDGWLkEDNRNVAVIHCKAGKGRTGVMICSYLLHDRLFD-TVKDALQFYGE
   . .... . ..|.  ...... . .    ||. |   . .  ....|  .  |....  |.||.|| ||||....  .| ..| .    | ||.  |
eytlrklelkkkkees..ekrevkqlhytnWpdhgvpespkslldlirkveksk.eaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivke

ARTQNAKGVTIPSQ
 |.| .. |.  .|
lRkqRpgmvqsleq

Y_phosphatase Protein-tyrosine phosphatase 60-171 1.6e-07 26.4 In-house 115-225 (235) alignment
Range on Protein: 60-171
Range on HMM: 115-225/235.0
THYTDHYKVYNLCSERfyDPKKFHKVTVYPFDDHNPP-PFELIQPFCEDVDGWLkEDNRNVAVIHCKAGKGRTGVMICSYLLHDRLFD-TVKDALQFYGE
   . .... . ..|.  ...... . .    ||. |   . .  ....|  .  |....  |.||.|| ||||....  .| ..| .    | ||.  |
eytlrklelkkkkees..ekrevkqlhytnWpdhgvpespkslldlirkveksk.eaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivke

ARTQNAKGVTIPSQ
 |.| .. |.  .|
lRkqRpgmvqsleq

subfamily_PTPN5_RR_pd Subfamily PTPN5_RR 57-161 4.8e-07 24.1 In-house 138-246 (274) alignment
Range on Protein: 57-161
Range on HMM: 138-246/274.0
YFDTHYTDHYKVYNLCSERFYDPKKFHKVTVYPF-DDHNPPPFELIQPFCEDVDGWLKEDNRN--VAVIHCKAGKGRTGVMICSYLLHDRLF-DTVKDAL
  ..  ...|.| .|  .   .... .      . | . |   . .  ....|.   .|.| .   .|.|| || ||||. |   .   .|  ..| | |
vekiverndysvrklvlkylerersvkhywytdWPdhksPddantlldlvleveesreeenaklapvvvhCsaGiGrtGcfiaisiavrqlreeivvdvl

QFYGEARTQ
.   . | .
kivcnlrld

subfamily_PTPMT1_pd Subfamily PTPMT1 80-162 4.8e-07 24.4 In-house 72-151 (171) alignment
Range on Protein: 80-162
Range on HMM: 72-151/171.0
KKFHKVTVYPFDDHNPPPFELIQPFCEDVDGWLKEDNRnVaVIHCKAGKGRTGVMICSYLLHDRLFDtVKDALQFYGEARTQN
   . ...   |  . | .| ..   | ..   .. .| |  .|||||.||.. .. .||.. . ..  ..||..  . | . 
lgveqlqlatvDfteapdleklekgvefiekvaskgkr.v.YvHCkaGrgRsatlvacylmkkekls.peeAlkalkkkRkii

PTPc_motif_SM00404 79-161 4.9e-07 24.7 In-house 44-123 (140) alignment
Range on Protein: 79-161
Range on HMM: 44-123/140.0
PKKFHKVTVYpFDD-HNPPPFELIQPFCEDVDGWlkEDNRNVAVIHCKAGKGRTGVMICSYLLHDRLFDtVKDALQFYGEARTQ
 ..|. . .   || .. . .. ..   . ..    |...   ..||.||  |.. .|. ||.. | .. ...|..|. | | .
nsgfqilqip.lddnekdklskyldkvldfiena..ekkggkvlVHCqaGvSRSatliiaYlmryrqls.laeayefvkerRpi

subfamily_Anemone-PTP-6_pd Subfamily Anemone-PTP-6 85-174 9.5e-07 23.2 In-house 182-271 (318) alignment
Range on Protein: 85-174
Range on HMM: 182-271/318.0
VTVYPFDDHNPPPFELIQpFCEDVDGWLKEDNRNVAVIHCKAGKGRTGVMICSYLLHDRL-FDTVKDALQFYGEARTQNAKGVTIPSQRRY
.| .|  .    . .|.. .  .|. . .. .... |.|| || ||||| |    | .|.  ... | .|.  . |.|    | . .|  .
ytsWpdegvpesgaslld.lvrqvskaqqksgagpivvhCsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqtedqyef

subfamily_DSP19_pd Subfamily DSP19 79-159 3.1e-06 21.6 In-house 53-130 (152) alignment
Range on Protein: 79-159
Range on HMM: 53-130/152.0
PKKFHKVTVYPFDDHNPPPFELIQPFCEDVDGWLKEDnrNVAVIHCKAGKGRTGVMICSYLLHDRLFdTVKDALQFYGEAR
||.|. ...  .|. .    . ..   . ..  ...|  .. ..||.||  |.  .. .||....   ....||.   |||
pkdftylsieilDlpetdllsylkealdFieearskd..gavlvHCnAGvSRsasvviaylmkkeel.sleealelvrear

subfamily_Anemone-PTP-5_pd Subfamily Anemone-PTP-5 104-177 9.7e-06 19.8 In-house 203-277 (319) alignment
Range on Protein: 104-177
Range on HMM: 203-277/319.0
FCEDVDG-WLKEDNRNVaVIHCKAGKGRTGVMICSYLLHDRL-FDTVKDALQFYGEARTQNAKGVTIPSQRRYVQY
. ...   . |.... . |.|| || ||||  |      .|.  ..| |  ..  . |||    |  |.| ... .
llkrirksrektqsgPi.vvhCsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiye