Gene PTPN1 in Amphimedon queenslandica

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family PTP
Subfamily PTPN1
Protein sequence
ID Type Fasta BLAST phosphatome Note
AqueP048_AA protein Get Run
AqueP048_AA_26-164 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_PTPN1_pd Subfamily PTPN1 27-118 5.6e-43 141.7 In-house 63-156 (290) alignment
Range on Protein: 27-118
Range on HMM: 63-156/290.0
LFQVEEVKRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQGQDEPEVMFG--RYRIELISIEDYSFFRLSHLQLENV
|...||.||||||||||||.|.||||||||||..|...||||..|....||. |||||..| |...   .....||| |..|......|.|||.
lveleeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvvekeqikcaqywPqgeeekellledtklkvkliseerksyytvrllelenl

0050432 (Phosphotyrosine protein) phosphatases II 32-167 1.8e-37 124.7 In-house 105-303 (308) alignment
Range on Protein: 32-167
Range on HMM: 105-303/308.0
EVKRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQGQDEPEVMFGRYRIELISIEDYSFFRLSHLQLENVEI-----------
 ..| .|.||||||.|...||.||||||.. | ||.|..|.|..||..|||  ...  ...|.....|.|.| .. . . .|.|.|..            
klprkfIatqgPlpntvedFwrmvweqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseevlddytvrtleltnlgdgesrtvthfhy

----------------------------------------------------EDTDDYNSVEIQEVLLNMRKQRLGLIQTPDQLRFSYVAILQRIWKRM
                                                    |  .  . | ..|..  .|.|| | .|||.|..| | |.|  .....
tnWpdhgvPpspeilldflelvrkslpggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylflyralleylklkl

0036941 (Phosphotyrosine protein) phosphatases II 30-167 7e-36 119.4 In-house 73-281 (297) alignment
Range on Protein: 30-167
Range on HMM: 73-281/297.0
VEEVKRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQGQDEPEVmFGRYRIELISIED--YSFFRLSHLQLEN----------
. ..|| .|.||||||.|...||.||||||.. |.||....|.|..||..|||  ..|. . .|.....|.|.|   .. . | .|....          
gydlkrkfIatqgPlpntvedFWrmvweqnvtvIvmltelvelgrekcaqywpleegeslt.ygdftvtllsvevvllddytlrtlevtdtgngesrtvt

----VEIEDTD--------------------------------------------------------DYNSVEIQEVLLNMRKQRLGLIQTPDQLRFSYV
      . | .                                                         .. | | |... .|.|| | .||..|.|| | 
hfhytgwpdhgvpespaslldfielvrkvlkllpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflye

AILQRIWKRM
|.|. ..|..
allellkkkl

0051299 (Phosphotyrosine protein) phosphatases II 32-163 7.3e-36 119.5 In-house 89-286 (288) alignment
Range on Protein: 32-163
Range on HMM: 89-286/288.0
EVKRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQgqdEPEVMFGRYRIELISIEDYSFFRLSHLQLENVEIED---------
. || .|.||||||.|...||.||||||.. | ||.|..|.|..||..|||.   .  ...|.....|.|.| .. . . .|...|... |         
nlkrkfIatqgPlpntvedFWrmvweqnvrvIvmltklvelgrekcaqYwpl...ggsltygditvtllseevlddytvrtlevtnldlldgdgesrtvt

------------T------------------------------------------------DDYNSVEIQEVLLNMRKQRLGLIQTPDQLRFSYVAILQR
                                                             .  . |.. |..  .|.|| |..|||.|.|| | |.|  
hfhytnwpdhgvpdspellldflrlvrkalasgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyealley

I
.
l

0046845 (Phosphotyrosine protein) phosphatases II 32-167 2.1e-35 117.9 In-house 74-278 (284) alignment
Range on Protein: 32-167
Range on HMM: 74-278/284.0
EVKRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQGqdEPEVMFGRYRIELISIEDYSFFRLSHLQLENVE------------
 .|. .|.||||||.|...||.||||||.. | ||....|.|..||..|||.   .  ...|.....|.|.| .. . . .|.|.|..            
yikkkfIatqgPlpntvedFwrmvweqnvrvIVmltelvengrekcaqYwple..gevltygdftvtllseevkddytvrtleltnlgytgesrtvthfh

-----------------------------------------------------------IEDTDDYNSVEIQEVLLNMRKQRLGLIQTPDQLRFSYVAIL
                                                           .| ....  | ..|..  .|.|| | .||..|.|| | |.|
ytswpdhgvppspedlleflrlvrellenlpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyeall

QRIWKRM
  .....
eylklkl

0047943 (Phosphotyrosine protein) phosphatases II 29-161 3.6e-35 117.2 In-house 71-270 (273) alignment
Range on Protein: 29-161
Range on HMM: 71-270/273.0
QVEEVKRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQGQDEPEVMFGRYRIELISIEDYSFFRLSHLQLENVEIED------
.. ..|| .|.||||||.|...||.||||||.. | ||....|.|..||..|||. ..| ....|.....|.|.| .. . . .|.|.|.. ..      
dgynlkrkfiatqgPlpntvedfwrmvweqnvrviVmLtelvelgrekcaqYwpleggelsltygkftvtllseetkddytvrtleltnlgtgesrtvth

--------T--D---------------------------------------------------DYNSVEIQEVLLNMRKQRLGLIQTPDQLRFSYVAILQ
                                                                .. | . |..  .|.|| | .|||.|.|| | |.| 
fhytgwpdhgvppslesllefielvrkalealpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyealle





0040438 (Phosphotyrosine protein) phosphatases II 32-169 5e-35 116.7 In-house 83-282 (317) alignment
Range on Protein: 32-169
Range on HMM: 83-282/317.0
EVKRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQgqdEPEVMFGRYRIELISIEDYSFFRLSHLQLENV-------------
. || .|.||||||.|...||.|||||... |.||... |.| .||..|||.   . .. .|.....|.|.| .. . | .|..|.              
nlkrkfIatqgPlpntvedFwrmvweqgvtvivmLteleelgrekcaqYwpl...getltygdftvtllseeelagitlrtlevedlgdsesrtvthfhy

---EIEDTD-------------------------------------------------DYNSVEIQEVLLNMRKQRLGLIQTPDQLRFSYVAILQRIWKR
      ..                                                   .. | ..|..  .|.|| | .|||.|.|| | |.|. . ..
tgWpdhgvppspdllldfleavrealedpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleylkrk

MAD
. .
ltl

0045450 (Phosphotyrosine protein) phosphatases II 29-163 1.2e-32 109.4 In-house 101-304 (307) alignment
Range on Protein: 29-163
Range on HMM: 101-304/307.0
QVEEVKRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQGqdEPEVMFGRYRIELISIEDYSFFRLSHLQLENV----------
..  .|| .|.||||||.|...||.|.|||... |.||....|.| .||..|||.   . |...|.....|.|.| .. . . .| ...           
dgydlkrkfIatqgPlpetvedFwrmlweqgvtvivmltelvelgrekcaqywPde..geeltygnftvtllseehldgytvrtlevtdldgtgesrtvt

-----EIEDTDDYNS--------------------------------------------------------VEIQEVLLNMRKQRLGLIQTPDQLRFSYV
     .  |..   |                                                        | ..|..  .|.|| | .|.|.|.|| | 
hfhytgwpdhgvppsfeelldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflye

AILQRI
|.|. .
allell

0043336 (Phosphotyrosine protein) phosphatases II 32-160 2e-31 104.9 In-house 85-274 (278) alignment
Range on Protein: 32-160
Range on HMM: 85-274/278.0
EVKRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPqgqdEPEVMFGRYRIELISIEDYSFFRLSHLQLENVEIEDT--------
.|.| .|.||||||.|...||.||||.... |.||... |.|..||..|||    .  . .|.....|...| .. . . .| ..|     .        
nvprkfiatqgPlpetvedFwrmvwelgvttivmLtelvelgrvkcaqYwp....ggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhy

----------D-----------------------------------------------DYNSVEIQEVLLNMRKQRLGLIQTPDQLRFSYVAIL
          .                                               ..  | ..|..  .|.|| | .|||.|.|| | |.|
lgwpdhgvpeslsllldflkavrealedsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyeall

0039614 (Phosphotyrosine protein) phosphatases II 33-163 7.2e-31 103.2 In-house 81-289 (297) alignment
Range on Protein: 33-163
Range on HMM: 81-289/297.0
V------------------KRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMnKCYPYWPQGQDepevMFGRYRIELISIEDYSFFRLSHLQ
|                  .| .|.||||||.|...||.|||||... |.||.|..|.|. ||..|||. ..    ..|.....|...| .. . . .| 
vdldsdYinAsyvdgydlltrkfIatqgPlpetvedFwrmvweqgvtvivmLtklvelgr.kcaqywpeegg....tygdftvtllkvehldgytvrtle

LENveiEDTD--------------------------------------------------------------------DYNSVEIQEVLLNMRKQRLGLI
..|   ..                                                                       .  | ..|..  .|.|| | .
vtn...ngesrtvthfqytgwpdhgvppslellleflelvrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgav

QTPDQLRFSYVAILQRI
|||.|.|| | |.|. .
qtpsqyrflydallell

0040439 (Phosphotyrosine protein) phosphatases II 30-163 6.8e-29 96.6 In-house 49-246 (249) alignment
Range on Protein: 30-163
Range on HMM: 49-246/249.0
VEEVKRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQgqdEPEVMFGRYRIELISIEDYSFFRLSHLQLENVEIED-------
.  .|| .|.||||||.|...||.|.||.... |.||... |.|..||..|||.   . .. .|.....|.|.| .. . . .|.|.|..  .       
gyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywpl...ggsleygdftvtllsvevkddytvrtleltnlydgesrtvlhi

-------TD-----------------------------------------------------DYNSVEIQEVLLNMRKQRLGLIQTPDQLRFSYVAILQR
       ..                                                      .. | ..|..  .|.|| | .|.|.|.|| | |.|. 
qytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdleeavkllrsqRpgavqnpeqyrflyeallel

I
.
l

0045098 (Phosphotyrosine protein) phosphatases II 34-163 1.2e-28 95.7 In-house 63-272 (278) alignment
Range on Protein: 34-163
Range on HMM: 63-272/278.0
KRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQgqdEPEVMFGRYRIELISIEDYSFFRLSHLQLENV---------------
.. .|.||||||.|...||.|.||.... |.||....|.|..||..|||    .  . .|.....|.|.| .. . | .| ..|.               
pkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaqywpe...ggsltygdftvtllseevlddytlrtllvtnltveredlesrgvthl

-----EIEDTDDYN--------------------------------------------------------------SVEIQEVLLNMRKQRLG-LIQTPD
     .  .. ...                                                               | ..|..  .|.|| |  .|...
hylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvlVHCsaGvgRtGtlvaaylmlelleggvdlleavkelrsqRpglavqnle

QLRFSYVAILQRI
|.|| | ..|. .
qyrflyefllell

0042113 (Phosphotyrosine protein) phosphatases II 31-161 2.2e-28 94.7 In-house 48-241 (245) alignment
Range on Protein: 31-161
Range on HMM: 48-241/245.0
EEVKRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQgqdEPEVMFGRYRIELISIEDYSFFRLSHLQLENV------------
 .... .|.||||||.|...||.|.||.... |.||... |.|..||..|||.   . .. .|.....|.|.| .. . . .|...|.            
yritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywpl...gesltygdftvtllseehlddytvrtlevtnlgddesrevihyh

--EIEDTD----------------------------------------------------DYNSVEIQEVLLNMRKQRLGLIQTPDQLRFSYVAILQ
   ..| .                                                     .  | ..|..  .|.|| | .|||.|.|| | |.|.
ylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleqlekelgvsleeavkelrsqRpgavqtpsqyrflyealle

0037934 (Phosphotyrosine protein) phosphatases II 33-161 6.4e-27 90.1 In-house 43-240 (243) alignment
Range on Protein: 33-161
Range on HMM: 43-240/243.0
VKRsYILTQGPLPHTCDH----FWQMVWEQNCKGILMLNKCIERGMNKCYPYWPqgqdE-PevMFGRYRIELISIEDYSFFRLSHLQLENVE--------
..| .|.||||||.|...    ||.|.||.... |.||....|.|..||..|||    .    ..|.....|.|.| .. . . .|.|||..        
tpr.liatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywp....gev..tygdftvtllseehlddytvrtlllenldlddltrlv

-------IED----T---------DDYN------------------------------------------SVEIQEVLLNMRKQRLG-LIQTPDQLRFSY
       . |    .         |. .                                          .| ..|..  .|.|| |  .|||.|.|| |
ihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtliaaylmllllgvdleeavkllreqRpgkavqtpsqyrfly

VAILQ
 |.|.
ealle

subfamily_PTPRB_pd Subfamily PTPRB 32-117 1.6e-25 84.7 In-house 91-174 (293) alignment
Range on Protein: 32-117
Range on HMM: 91-174/293.0
EVKRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQgqDEPEVMFGRYRIELISIEDYSFFRLSHLQLEN
. .| .| ||||||.| |.||.||||.... |.|| ...|.|  ||  |||.  || .|..|  ...|.. |... . . .|..|.
nsprefiatqGPlpetvddfWrmvwekkssiivmltqlvekgkvkCeeYWPa..deepvlyGdikvtlvaeeeledwvirelkiek

Y_phosphatase Protein-tyrosine phosphatase 33-120 1.7e-25 85.2 Pfam-A 40-128 (235) alignment
Range on Protein: 33-120
Range on HMM: 40-128/235.0
VKRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQGQDEpEVMFGRYRIELI-SIE-DYSFFRLSHLQLENVEI
 |...|.|||||..|...||.|||....| | ||... |.| .|| .|||. ..| ....|....||  ... | . . |..|.|.. . 
ekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeee.sltygdikvelkekekedekeytlrklelkkkke

Y_phosphatase Protein-tyrosine phosphatase 33-120 1.7e-25 85.2 In-house 40-128 (235) alignment
Range on Protein: 33-120
Range on HMM: 40-128/235.0
VKRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQGQDEpEVMFGRYRIELI-SIE-DYSFFRLSHLQLENVEI
 |...|.|||||..|...||.|||....| | ||... |.| .|| .|||. ..| ....|....||  ... | . . |..|.|.. . 
ekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeee.sltygdikvelkekekedekeytlrklelkkkke

DSPc_SM00195 31-119 6.1e-25 83.4 In-house 65-153 (263) alignment
Range on Protein: 31-119
Range on HMM: 65-153/263.0
EEVKRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQGQdEPEVMFGRYRIELISIEDYS-FFRLSHLQLENVE
.. |..||.||||||.|...||.||||...| |.||... |.| .||. |||. . . .  ||.....|.. | ..  . | .|.|.. .
ankkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengkekcdrywpees.ggketfgkisvklvevekkkdeiilrtleltkeg

PTPc_SM00194 31-119 6.1e-25 83.4 In-house 65-153 (263) alignment
Range on Protein: 31-119
Range on HMM: 65-153/263.0
EEVKRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQGQdEPEVMFGRYRIELISIEDYS-FFRLSHLQLENVE
.. |..||.||||||.|...||.||||...| |.||... |.| .||. |||. . . .  ||.....|.. | ..  . | .|.|.. .
ankkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengkekcdrywpees.ggketfgkisvklvevekkkdeiilrtleltkeg

subfamily_PTPRD_pd Subfamily PTPRD 34-119 3e-24 80.6 In-house 90-172 (564) alignment
Range on Protein: 34-119
Range on HMM: 90-172/564.0
KRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQGqDepEVMFGRYRIELISIEDYSFFRLSHLQLENVE
...|| |||||..|.. ||.||||||.. | ||.|. |.| .||  |||.  .  .  .|.. ..| . |... . . ...|.. .
rkayIAtqgPlaetiedFWRmvweqnsstiVmltkleEkgkvkchkYWPek.g..tetygeltVtleeeeeladyeirtfklkkkk

subfamily_PTPN3_pd Subfamily PTPN3 34-119 4.6e-24 79.8 In-house 83-166 (280) alignment
Range on Protein: 34-119
Range on HMM: 83-166/280.0
KRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQGQDepEVMFGRYRIELISIEDYSFFRLSHLQLENVE
   || |||||..|. .||||||||... |.||   .|||  ||. |||. .|  |. .|...... . .  . . | .| |.. |
vnryiatqGPlaktatdfWqmvweqksslivmlttlverGrvkChqyWPeted..eleygefsvkcekedetksyvlrelvlkdke

subfamily_PTPN13_pd Subfamily PTPN13 29-121 6.9e-24 79.6 In-house 71-163 (273) alignment
Range on Protein: 29-121
Range on HMM: 71-163/273.0
QVEEVKRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQGQDEPEVMFGRYRIELISIEDYSFFRLSHLQLENVEIE
.|.. . .||..|||||.|.. ||||||||... | |. .  |.|  ||  |||. .... .. .|...||. ..... | ...|.....| .
pvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvkchrywPesknkklkvsnrlevellkvqkldgfvvralavkdsesg

subfamily_PTPN6_pd Subfamily PTPN6 30-121 2.7e-23 77.4 In-house 93-182 (306) alignment
Range on Protein: 30-121
Range on HMM: 93-182/306.0
VEEVKRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQGQDEPEvmFGRYRIELISIEDYSFFRLSHLQLENVEIE
|.. ..||| ||| |..|   ||.|||..|.. |.|. | .||| .||..|||. ....|  .|..... .| .. . . | .|...... .
vkgsdksyiatqgclettvsdFWrmvwqensrvivmttkevErgkekCarYWPdeeekee..yGkisvtnvseksladYilRelsvskkkkk

subfamily_PTPN9_pd Subfamily PTPN9 34-121 3.1e-23 77.3 In-house 84-170 (297) alignment
Range on Protein: 34-121
Range on HMM: 84-170/297.0
KRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQGQDEpEVMFGRYRIELISIEDYSFFRLSHLQLENVEIE
|...| |||||..|.. ||.|||||..  |.|  ...|||  ||  |||.....    || .... ...| .. .. . |...||. |
kkafiatqGplkktvsdfWrmvWeqevlvivmttrvvergrlkcgqyWpleees.saefgdlsvsnveveeeedykvrvleiknvkte

subfamily_Anemone-PTP-6_pd Subfamily Anemone-PTP-6 33-122 1.4e-22 75.2 In-house 87-173 (318) alignment
Range on Protein: 33-122
Range on HMM: 87-173/318.0
VKRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQGQdepEVMFGRYRIELISIEDYSFFRLSHLQLENVEIED
 |..|| .|.|||.|.. ||.||||||.. |.|| .. ||| .|.  |||. .      .|. ..|| .  ..| . | ...... | |.
rkkayiaaqaPlpetieDfWrmvWeqnsavivmltqeeergkakvhryWPskg...srsygklvvelkeevelsdyvlrefkvtrteeee

subfamily_Urchin-PTPRB-like_pd Subfamily Urchin-PTPRB-like 28-115 4.1e-22 73.6 In-house 83-168 (288) alignment
Range on Protein: 28-115
Range on HMM: 83-168/288.0
FQVEEVKRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQGQDepEVMFGRYRIELISIEDYSFFRLSHLQL
...|. |. || |||||..| ..||..|.|.. . |.||.. .|.| .||  |||....  .. .|   ..|.. ..   | | .| |
idgekkkkkyiatqgPladtvndfWelvyenktstivmltelveggktkCeeYWPdadk..pknyGsvtvtlveskeledfvlrklll

subfamily_PTPRG_pd Subfamily PTPRG 35-126 6e-22 72.6 In-house 91-179 (563) alignment
Range on Protein: 35-126
Range on HMM: 91-179/563.0
RSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQgqDEPEvMFGRYRIELISIEDYSFFRLSHLQLENVEIEDTDDY
. .| |||||..|.| ||.|.|||| . | |. .  ||| .||  |||.  ||.|  .|  .. ||. |  .     .|...|........ 
kafiatqgplkdtfddFWrmiWeqnvaiivmitnlvergrrkcdvYWPk..dese.tygalqvtlieeevlalytvrtlviknlklkkkkqc

subfamily_PTPN14_pd Subfamily PTPN14 30-106 2.1e-21 71.2 In-house 88-165 (300) alignment
Range on Protein: 30-106
Range on HMM: 88-165/300.0
VEEVKRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQG-QDEPEVMFGRYRIELISIEDYS
|   .|||| .||||..|.  ||||||||. . |.|| . .| | .|.. |.|.  . . .| ||....     || .
vggkersyivaqgPleltvqdfWqmvWeqgvqlivmlteeeedgkeksfkyfPkleskkktvefgkfkvttkfsedsd

subfamily_Choan-PTP-1_pd Subfamily Choan-PTP-1 33-119 2.1e-21 71.2 In-house 82-166 (281) alignment
Range on Protein: 33-119
Range on HMM: 82-166/281.0
VKRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQGQDepEVMFGRYRIELISIEDYSFFRLSHLQLENVE
 .. || ||||.|.....||||||||. . | |. . || |  ||. |||...   |. .| .... .. |. . .   ...||. .
gekeyiatqgPvPaslvafWqmvweqkvsaivmvtreieagklkChrYWPddns..elkygdvtvkstaeeekatyierkfkleres

subfamily_PTPN1_pd Subfamily PTPN1 118-171 2e-19 64.4 In-house 226-279 (290) alignment
Range on Protein: 118-171
Range on HMM: 226-279/290.0
VEIEDTDDYNSVEIQEVLLNMRKQRLGLIQTPDQLRFSYVAILQRIWKRMADAD
|.||..||..||.|..|||..||.|||||||.|||||||.|||. . . . |. 
vliekkddlssvdikkvllelrkyrlGliqtadqlrfsylaileGakvikgdss

subfamily_Anemone-PTP-4_pd Subfamily Anemone-PTP-4 33-113 2.5e-19 64.4 In-house 43-121 (237) alignment
Range on Protein: 33-113
Range on HMM: 43-121/237.0
VKRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQGqDEPEvMFGRYRIELISIEDYSFFRLSHL
  ..|| .||||  .|| ||||||...|  |.||   ||.   ||. |||.  |.|.  .| . . |   |..| . .  |
tpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpst.dqpa.aygvltvslkkkeefsdytvrsl

subfamily_PTPN5_RR_pd Subfamily PTPN5_RR 32-116 4.4e-19 63.6 In-house 70-155 (274) alignment
Range on Protein: 32-116
Range on HMM: 70-155/274.0
EVKRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQGQDE-PEVMFGRYRIELISIEDYSFFRLSHLQLE
|... |. ||||||.| . ||.|....... |.|| |  |. ..||  |.|. .|   .  .|   |.  .| .   ... .| |.
eeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneqkCavyfPdaedyeiserygdveikvekiverndysvrklvlk

0051429 (Phosphotyrosine protein) phosphatases II 34-165 7.1e-19 64.0 In-house 21-227 (272) alignment
Range on Protein: 34-165
Range on HMM: 21-227/272.0
KRSYILTQGPLPHTCDHFWQMvWEQNCKGILMLNKCIERGMNKCYPYWP---------QGQDEPEVMFGRYRIELISIEDYSFFRLSHLQLENV------
.. .....||||.|...||.. .|...| |..| .. |||..||..|||          . ..|.. .|..|. |.|.| .... | .|.|...      
pgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseellldyilrellltlllsagea

-----------------------------------------------------EIEDTDDYNSVE--------IQEVLLNMRKQRLGLIQTPDQLRFSYV
                                                      ... ..   |.        ..|..  .|.|| | .||..|..| | 
revmhlhytdwpdhgvpqeallellellldggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlyleeaveelraqrpgavqteeqylflye

AILQRIWK
|.|. . .
allellrs

subfamily_Sponge-PTP11_pd Subfamily Sponge-PTP11 34-119 9.9e-19 62.3 In-house 90-172 (290) alignment
Range on Protein: 34-119
Range on HMM: 90-172/290.0
KRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQGqDEPEvmFGRYRIELISIEDYSFFRLSHLQLENVE
|..||.||||...|  .||...|....  |.|| . || | .||. |||.  |  .  .| ..|.|.. | .. ..  .|...| .
kkqyiatqgpvsntlvdFWkliwqekvtiivmltniieegkvkCqqYWpds.dtka..ygefsikllneetlneyierklevknkn

subfamily_Choan-PTP-4_pd Subfamily Choan-PTP-4 27-112 1.2e-18 62.0 In-house 68-154 (297) alignment
Range on Protein: 27-112
Range on HMM: 68-154/297.0
LFQVEEVKRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQGQDEpEVMFGRYRIELISIE--DYSFFRLSH
 |  || .  |||.||||  | | ||..|.||. . | |. |  | | .||.||||. ..|     | . .| .|    ..    |. 
vfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrdkcapywpsvvqe.rlkagdvvveflsstsdefdrvilte

subfamily_PTPN12_pd Subfamily PTPN12 31-105 1.2e-18 62.1 In-house 79-152 (290) alignment
Range on Protein: 31-105
Range on HMM: 79-152/290.0
EEVKRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQGQDEpEVMFGRYRIELISIEDY
 | | .|| .|||||.| | ||.|.||.| . ..|. . .| | .||  |||. ..| |..|| ....|.. .  
vegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCerYWpeegee.elefgefevtleeekav

subfamily_Choan-PTP-2_pd Subfamily Choan-PTP-2 32-117 1.8e-18 61.5 In-house 61-147 (270) alignment
Range on Protein: 32-117
Range on HMM: 61-147/270.0
EVKRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQGQDE-PEVMFGRYRIELISIEDYSFFRLSHLQLEN
. |..|| ..|||| |  .||.|.||.. . |.|. .  |.| .||  |||. ..|  ....|  ..  .| |  ....| .|.||.
gekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkekvkledgkikvlalseekeegyiltrlrlee

subfamily_Sponge-PTP8_pd Subfamily Sponge-PTP8 34-117 2e-18 61.6 In-house 88-170 (305) alignment
Range on Protein: 34-117
Range on HMM: 88-170/305.0
KRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQGQDEPEvMFGRYRIELISIEDYSFFRLSHLQLEN
| .||..||||..| . ||....|   . |.|| | .| | .||. |||. . |..  ||.. .|| | . .| .   .|.. .
kkkyivaqgPlkntvadfWrliveekvstivmltklveggkdkCrqYWpesktekk.efgefsvelksektasdyieRklkisi

0049260 (Phosphotyrosine protein) phosphatases II 35-156 2e-18 62.0 In-house 9-143 (152) alignment
Range on Protein: 35-156
Range on HMM: 9-143/152.0
RSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWpqgqdepevmfgryRIELISIEDYSFFRLSHLQLENVEIEDT-----------
. .| ||||.|.|...||.|..|.... |.||... |.|  ||. |.              ..  . ..|..   || | |. ... .            
fefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi..............qylhlpwpDhgvpdlsqlllflllfieklaldkggpvlV

------------------DdyNSVEIQEVLLNMRKQRLGLIQTPDQLRFSY
                     . |...|..  .|..| | ...|.|||| |
HCsaGvgRtgtlvaaylml..lgvsleeavalvrekRpgavpnpgqlrfly

0046846 (Phosphotyrosine protein) phosphatases II 37-160 4.4e-18 61.1 In-house 25-170 (176) alignment
Range on Protein: 37-160
Range on HMM: 25-170/176.0
YILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQGQDEPEvmfgryRIELISIEDYSFFRLSHLQLENVEIEDTDDYN---------
.| ||||||.|. .|..|..|.... ...|....| |. ||. |||. ...        ..  . ..|..   |..|.    .|..  . .         
piatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgi......qylhlpwpDhgvpdlelllellefirealkeggpvlVHCsa

------------------SVEIQEVLLNMRKQRL-GLIQTPDQLRFSYVAIL
                   . ..|.|  .|.||  | .|||.|.|| | ..|
GigRtgtlvaayllelekglsveealalvreqRplgavqtpeQyrflyefel

0041856 (Phosphotyrosine protein) phosphatases II 33-163 7.3e-18 60.2 In-house 32-171 (182) alignment
Range on Protein: 33-163
Range on HMM: 32-171/182.0
VKRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNkciergmnkCYPYWPqgqdepevmfgryrielisiedySFFRLSHLQLENVEIEDTDD-------
  . .|.|||||..|. .|..|..|.... |..|.         ...|||                       ...    .|. .. ..| .        
patrfiatqgpllstvadflrmlkelgittivnlt.........eelywp.......................ellerlgiqylylpwpDhgvpdldell

----------------------------------YNSVEIQEVLLNMRKQRLGLIQTPDQLRFSYVAILQRI
                                  ...| ..|..  .|..| | ..||.|..| . |.|...
dfieevleeggpvlVHCsaGvgRtgtlvaaylmkklgvsleeavklvrsrRpgmvitpnqyfflqlallell

subfamily_PTPRA_pd Subfamily PTPRA 34-101 7.4e-18 59.5 In-house 100-164 (330) alignment
Range on Protein: 34-101
Range on HMM: 100-164/330.0
KRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPqgqDEPEVMFGRYRIELIS
| ..| .|||. .| . ||.|.|||.   |.|| .  ||  .||. |||   ||  | .|  |.|.  
kdkfiaaqGPkeetvedfwrmiweqksativmltelkerkeekcaqywP...deGlvtyGnirveved

subfamily_Sponge-PTP10_pd Subfamily Sponge-PTP10 34-118 1.9e-17 58.2 In-house 85-166 (287) alignment
Range on Protein: 34-118
Range on HMM: 85-166/287.0
KRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQGQDepeVMFGRYRIELISIEDYSFFRLSHLQLENV
|. .|....|. .|   ||......| . |.|| .  |   ..|| |||...    |..| |.|||.. | .. .   .|...| 
kkafiiaesPmfntarnfWkliddrnvtaivmlcqekendeevcyqyWpeeks...vvlGeyniellneevnagyierklevknk

subfamily_PTPRK_pd Subfamily PTPRK 35-103 2.6e-17 57.6 In-house 86-150 (314) alignment
Range on Protein: 35-103
Range on HMM: 86-150/314.0
RSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPqgqDEPEVmFGRYRIELISIE
. .| |||||..|   ||..|...||  |.||.. .| |  ||. |||   .. || .|  ..||.. |
aafivtqgPlqetvkdfWrlvydencasivmltelvevgrvkClkyWP...edtev.ygdikvelvete

subfamily_Anemone-PTP-2_pd Subfamily Anemone-PTP-2 34-118 2.9e-17 57.9 In-house 98-179 (298) alignment
Range on Protein: 34-118
Range on HMM: 98-179/298.0
KRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQGQDEpevMFGRYRIELISIEDYSFFRLSHLQLENV
. ..|.||.||..|   ||.||.|.. . | ||..  | .  |.  |||. . |    .|. ...| | |... .   .|.... 
rnafiatqaPltetvedFWrmvteedigtiVmltnleeldktkyhkywPdegke...tygeitvsllskeefadlivrklkvskk

subfamily_Urchin-PTP-6_pd Subfamily Urchin-PTP-6 34-104 3.7e-17 56.6 In-house 85-154 (515) alignment
Range on Protein: 34-104
Range on HMM: 85-154/515.0
KRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQGQDEpEVMFGRYRIELISIED
 ..|| .|||.. . | ||..|...|   | |..|  |    ||  |||.   .  | || ...||.|.| 
dkayiasqgPnkasvddfWrlvlqenvttiamvtklkegdkikcgkyWPdkpgd.svkfGsikvelvslea

subfamily_PTPRN_pd Subfamily PTPRN 34-103 9.6e-17 55.6 In-house 99-165 (297) alignment
Range on Protein: 34-103
Range on HMM: 99-165/297.0
KRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPqgqDEPEVMFGRYRIELISIE
. .|| |||||..|  .|||||||| .  |..| .  | |...|. |||   || . ... | ..|.|  
apayiatqgplastvadfwqmvweqGvvvivnltrleeegvkqckrywp...deGsevyhiyevhlvseh

0036282 (Phosphotyrosine protein) phosphatases II 32-154 1.1e-16 56.4 In-house 14-161 (174) alignment
Range on Protein: 32-154
Range on HMM: 14-161/174.0
EVKRSYILTQGPLPhtcdhFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQGQDEpeVMFGRYRIELISIEDYSFFRLSHLQLENVEIEDTDDY-----
.. . .|..||||.     ||.|..|.... ..||....|.|. ||. |||  ..        ...  . ..|.. . || |.    ..|.         
yitprliagqgpla.....fwemlkelgittvvmlleekelglykcinywpelred..lerlgiqylylpwpDhgvpdlsillefvkfveealsedpggp

---------------------------NSVEIQEVLLNMRKQRLGLIQTPDQLRF
                           . |.. ...  .|.|| | .|||.|.||
vlVHCsaGvgRtGtlvaaylmlrglleslvdaldlvrelRlqrpgmvqtpsQyrf

subfamily_Urchin-PTP-7_pd Subfamily Urchin-PTP-7 33-106 1.7e-16 55.0 In-house 90-159 (315) alignment
Range on Protein: 33-106
Range on HMM: 90-159/315.0
VKRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQGqdepEVMFGRYRIELISIEDYS
 || || .|||.. . . ||..|.|...  |.||.. .|.  .|.  |||      .|..|.. . ..| | ..
kkrryiaaqgpnvasvkdfwrlvfeedigkivmltnlvegekrkaekywpdk....kviyGkitvtrkseevnt

subfamily_Urchin-PTP-1_pd Subfamily Urchin-PTP-1 34-104 1.7e-16 55.0 In-house 86-155 (315) alignment
Range on Protein: 34-104
Range on HMM: 86-155/315.0
KRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQgQDEPEVMFGRYRIELISIED
 ..|| .||||. . | ||.||....   | |..|  |    ||  |||. ..   | || ...||.|.| 
dkayiasqgPlkasvddfwrmvlqekvttivmvtkkqegdkikcrqywPd.rkadsvefGsikvellslea

subfamily_PTPN23_pd Subfamily PTPN23 36-118 2.9e-16 54.1 In-house 84-165 (288) alignment
Range on Protein: 36-118
Range on HMM: 84-165/288.0
SYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQGQDEPEvMFGRYRIELISIEDYSFFRLSHLQLENV
..| ||.||. |   ||.||.||  . | || .  |.| .|.  |||. ..|..  || ... | | .. . .   .|.||  
dfiatqaPlqstlnDFWlmvyeqkssviVmllskeelgkpkvdrYwPedkgetv.kfgdlsvtlksvretethvervlkletl

subfamily_egg_pd Subfamily egg 36-118 3e-16 54.0 In-house 84-165 (307) alignment
Range on Protein: 36-118
Range on HMM: 84-165/307.0
SYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERgmNKCYPYWPQGQDEPEVM-FGRYRIELISIEDY--SFFRLSHLQLenV
 .||.| ||  | | ||.||...... |.||.   |   ..|  |||. .... |.  | .||| . ...    .||...|.|  |
efilaqaplkntvddfwrmvfqeevqyivmltsrkes..erceyywpkaesdslvtvpGslrienlkvdskadplfrvtklkl..v

subfamily_Nvec-PTP-2_pd Subfamily Nvec-PTP-2 32-117 3.2e-16 54.3 In-house 49-130 (250) alignment
Range on Protein: 32-117
Range on HMM: 49-130/250.0
EVKRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNkCYPYWPQgqDEPEvMFGRYRIELISIEDYSFFRLSHLQLEN
. ....| |||||..|  .||.||.|.. . |.||..  | . . .  |||   ...|  .|  ...| | | .. .   .|.| .
derkafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqywPv..ekae.kyGdvtvsllskeefadytkrklklsk

subfamily_Choan-PTP-3_pd Subfamily Choan-PTP-3 35-103 6e-16 53.1 In-house 80-146 (287) alignment
Range on Protein: 35-103
Range on HMM: 80-146/287.0
RSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQGqDEPeVMFGRYRIELISIE
 ..| .|||.. |   ||..|.|..   .... . .| . .||| |||.  . | .. | | . |.. .
eafiaaqgPiaatvrdfwravletrsasvitmtreveearlkcykywPer.evP.mrvGGysvvlldyd

subfamily_Fungi-PTP1_pd Subfamily Fungi-PTP1 36-122 8.6e-16 52.6 In-house 105-191 (350) alignment
Range on Protein: 36-122
Range on HMM: 105-191/350.0
SYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQGQDEP-EVMFGRYRIELISIEDYSFFRlSHLQLENVEIED
 || ||.||| | | |.... . . | ||.|.. .| ...||| ||..|. .   | .   . . ..|.| | .  .... | .. ..
kYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcyrYWqegsydditvklaskwenimgindsslys.advkkeasdndn

subfamily_Urchin-PTPRA_pd Subfamily Urchin-PTPRA 34-117 2.7e-15 51.5 In-house 103-177 (319) alignment
Range on Protein: 34-117
Range on HMM: 103-177/319.0
KRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNkciergMNKCYPYWPQGQDEpevMFGRYRIELISIEDYSFFRLSHLQLEN
|  || .||||. | . ||.|.||.||  |..|        .||  |||.  ..     .|. ... |.|. . . . ...| .
kdkyiaaqGPldntladfWrmiweyncstivllt......kdkcsqywplkivi...keerfkvkvdsveetaeyvvrdielse

subfamily_Urchin-PTP-8_pd Subfamily Urchin-PTP-8 34-117 3.1e-15 51.4 In-house 67-141 (284) alignment
Range on Protein: 34-117
Range on HMM: 67-141/284.0
KRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNkciergMNKCYPYWPQGQDEpevMFGRYRIELISIEDYSFFRLSHLQLEN
|  || |||||. | . ||.|.||.||  |..|        .||  |||.  ..     .|..... |.|. . . . ...| .
kdkyiatqGPldntladfWrmiweyncstivllt......kdkcsqywplkivi...keerfkvkvdsveeseeyvvrdielse

subfamily_Anemone-PTP-5_pd Subfamily Anemone-PTP-5 34-117 5e-15 50.4 In-house 90-170 (319) alignment
Range on Protein: 34-117
Range on HMM: 90-170/319.0
KRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQGQdepEVMFGRYRIELISIEDYSFFRLSHLQLEN
.. .| ||.|| .| . ||.||||...  ..||.|  |..  |.  |||. .    . .||. ..| . |  . .  ..|.|..
rekfiatqaPlentiedfWrmvWeeessivvmltklveklkvklkkywpeen...feeyGrlivtleeeeeledyiirklklnk

subfamily_Ptp69D_pd Subfamily Ptp69D 34-121 7.8e-15 49.8 In-house 90-174 (307) alignment
Range on Protein: 34-121
Range on HMM: 90-174/307.0
KRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQGqdePEVMFGRYRIELISIEDYSFFRLSHLQLENVEIE
|...|  |.|.  | . ||.|..||. . | || .  |   .||  |||.     || .|   ..|.| |  | .   .|.. ... |
kkkfiaaqdPveatigDfWRmiaeqevtlivmlsnlteknrkkcakYWpie...devqygdilvklvseekhsdyiiReldvskkkee

subfamily_Sponge-PTP5_pd Subfamily Sponge-PTP5 30-99 9.2e-15 49.3 In-house 70-136 (283) alignment
Range on Protein: 30-99
Range on HMM: 70-136/283.0
VEEVKRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQgqdEPEVMFGRYRIEL
 .. .. || .|.|| .|   ||.||....   |.|| |  |    ||  |||.   .  . .| . . |
sykqdkkyiiaqsPldrtvvdfWkmvfdekitaivmltklqedlrikCsqyWPk...rGsedyGeftvtl

subfamily_CG7180_pd Subfamily CG7180 34-115 1.1e-14 48.7 In-house 84-161 (296) alignment
Range on Protein: 34-115
Range on HMM: 84-161/296.0
KRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMnKCYPYWPQGQdepEVMFGRYRIELISIEDYSFFRLSHLQL
|. || |..|  .| | ||..|...... . .| |  .    ..  |||. .   .  .|   .|... . |. ..   ..|
kkeyivteapkketvdefWrlvydeeisavvvLtktfdfak.mypsywpnks...keqygeifveiveekqyanlkirtfkl

subfamily_Urchin-PTP-3_pd Subfamily Urchin-PTP-3 33-119 1.9e-14 48.5 In-house 89-173 (325) alignment
Range on Protein: 33-119
Range on HMM: 89-173/325.0
VKRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKcIERGMNKCYPYWPQGQDEpEVMFGRYRIELISIEDYSFFRLSHLQLENVE
 |  .. .| ||..| . .|..| . .|  ...||. .. | ..|  |||.   .  . ||  ...|..||..| .    |.. .|.
kkdvflaaqaPltatindlWrlvldWrcsvvvvlne.ldlgkdrcavywpkemgk.sktfGglevklrtieeisdyvhrvldvkqvk

subfamily_Cele-PTP-10_pd Subfamily Cele-PTP-10 35-100 7.3e-14 46.1 In-house 96-161 (305) alignment
Range on Protein: 35-100
Range on HMM: 96-161/305.0
RSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQGQDEPEVMFGRYRIELI
. .| .|||| .| |.|| || ... . |.|| | .| |  ||  |||  | |   . .   .| .
krficaqgpldqtidefwwmviqnkveqivmlcktvelgklkcaqywpaaqgeklelksgivvenv

0043147 (Phosphotyrosine protein) phosphatases II 33-156 1.4e-13 46.4 In-house 18-154 (172) alignment
Range on Protein: 33-156
Range on HMM: 18-154/172.0
VKRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCiergmnkcypywpqGQDEPEVMFGRYRIELISIEDYSFFrLSHLQLENVEIEDT---------
. ...| |||||..|...||.|..|.... |..|...                | . ..   ...  ....|.. . |. | || .|. |.         
ipdrfiatqgplrntladfwrmlkelgithivnltel..............lydpellerlgiqylylpwpDhgvp.llellleflefidellalspggp

---------------------DdyNSVEIQEVLLNMRKQRLGLIQTPDQLRFSY
                         .. ..|..  .|..| | .|.|.|.|| |
vlVHCsaGvgRtgtlvaaylml..lglsleeavalvrekRpgavqnpsqyrfly

subfamily_CG42327_pd Subfamily CG42327 32-122 1.6e-13 45.0 In-house 69-160 (319) alignment
Range on Protein: 32-122
Range on HMM: 69-160/319.0
EVKRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQGQDEPE-VMFGRYRIELISIEDYSFFRLSHLQLENVEIED
. . ||| .| .|  .   ||..||||. . |. | .  | |...|  |.|  .  ..  ..| ... |   |    . .| | | .|. | 
dapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlselGikvcaeylPtketldntslyGdilvtlkgrevkdryaistlllkrvdkee

subfamily_Cele-PTP-15_pd Subfamily Cele-PTP-15 35-105 2.8e-13 44.5 In-house 75-144 (285) alignment
Range on Protein: 35-105
Range on HMM: 75-144/285.0
RSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQGQDEpEVMFGRYRIELISIEDY
 .|| |||||| |   ||.|.....   .|||   .| |..||  |.|.   |  | ||.| | |   .. 
styittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyypeklge.vvkfgkyeitlteckee

subfamily_ptpA1_pd Subfamily ptpA1 35-84 3.1e-13 44.3 In-house 89-138 (418) alignment
Range on Protein: 35-84
Range on HMM: 89-138/418.0
RSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQG
. .| |||||| |   ||.||||. |. |.||..  |    ||  |||. 
kqfictqgplpntiadfwrmvwenrcriivmlsresencrikcdrywpeq

subfamily_Urchin-PTP-5_pd Subfamily Urchin-PTP-5 31-109 3.9e-13 44.2 In-house 88-162 (297) alignment
Range on Protein: 31-109
Range on HMM: 88-162/297.0
EEVKRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMnKCYPYWPqgqDEPEVMFGRYRIELISIEDYSFFR
. .|  .| || | . | . ||.||.... . |.|||.  ||   ||  ||.   |.  . ||   ..| |... . | 
kgnkhrlittqmPmkatvadfWamvldeqvstivmlnddnerdk.kcaryWs...dkgvttfGdvsvvllsvsereGfi

subfamily_Cele-PTP-20_pd Subfamily Cele-PTP-20 30-98 6.8e-13 42.9 In-house 89-156 (290) alignment
Range on Protein: 30-98
Range on HMM: 89-156/290.0
VEEVKRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQGQDEpEVMFGRYRIE
|. .|  .|||||.|  |   .|.|| ...   | || . || |  || .|.|. . |  . || . . 
vkGlkamfiltqGalkdtvidiwrmvlqekvaaivmlceliedGkakceqyypekeGe.vltfGeitvl

subfamily_Sponge-PTP9_pd Subfamily Sponge-PTP9 34-124 7.1e-13 42.9 In-house 84-170 (301) alignment
Range on Protein: 34-124
Range on HMM: 84-170/301.0
KRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQGQDEPEvMFGRYRIELISIEDYSFFRLSHLqleNVEIEDTD
|. .| .|||. .|   ||...|..    |.|. .  |.  .||. |||... | |  ||   ..|..   |  | . .|   || |.|. 
kkkfiaaqgpmkktlvdfWrliwqekpvsivmvtnlkegtkskceqywpnseaese.efgpftvtlvneqvyPdfvirql...nvkiqdgs

subfamily_Cele-PTP-19_pd Subfamily Cele-PTP-19 35-103 8.6e-13 42.7 In-house 90-157 (301) alignment
Range on Protein: 35-103
Range on HMM: 90-157/301.0
RSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQGQDEpEVMFGRYRIELISIE
. .| |||||. |.. || |.   . . | || . .|. ..||  | |.   | ..  ||..|.. . |
hrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkise.kldigrfkikiknke

subfamily_Cele-PTP-6_pd Subfamily Cele-PTP-6 35-90 5.2e-12 40.4 In-house 82-137 (307) alignment
Range on Protein: 35-90
Range on HMM: 82-137/307.0
RSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQGQDEPEV
. .| .||||  |  .|| |. ... . ..|| |.|| .  ||  |||  . .  |
kkficaqgplentqysfwamaiqekvesvimlckvielakikceqywpleegqklv

subfamily_Cele-PTP-13_pd Subfamily Cele-PTP-13 33-84 5.3e-12 40.0 In-house 79-130 (281) alignment
Range on Protein: 33-84
Range on HMM: 79-130/281.0
VKRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQG
.|| |||||||   |   ||.|.|..|   |.|| . .|   .||  |.|. 
lkrgyiltqgpkketradfwrmiwqenttaivmlcqfletnrekcaeyfprn

subfamily_Cele-PTP-14_pd Subfamily Cele-PTP-14 33-83 5.7e-12 39.8 In-house 92-142 (310) alignment
Range on Protein: 33-83
Range on HMM: 92-142/310.0
VKRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQ
.. ..| .|||| ||   ||.|.... .. ||.| |  | |  ||  ||| 
lrstficsqgplqhtiidfwrmifqeraesilllckvgeegrpkcvgywps

0051082 (Phosphotyrosine protein) phosphatases II 27-159 4.2e-11 38.2 In-house 5-149 (151) alignment
Range on Protein: 27-159
Range on HMM: 5-149/151.0
LFQVEEVKRSYILTQGPLPhtcdHFWQMVWEQNCKGILMLNKCIERGmnKCYPYWPQ-GqdepevmfgryrielisiedysfF-------------RLSH
..    |   .....|||.    .|.....|...| |..|..  |||  .|. |.|. |                       .              |..
yinfsyvtgglyrsggpla....dflellkelgiktivnlrseeerg..ycpeylpelg.......................ievlhipildwpdpglpl

LQ---LENVEIEDTD-DY-----------------------NSVEIQEVLLNMRKQRLGLIQTPDQLRFSYVAI
..   || .|. . . ..                         | ..|.|  .|..| |..|...| .| . |.
sfdavleflellldkkngpvlvHCsaGkgRTGtlvalylmllgvsleealeeyrlkrpgvvqpnqqflfqlfal

subfamily_Cele-PTP-18_pd Subfamily Cele-PTP-18 35-92 5.2e-11 36.8 In-house 88-144 (305) alignment
Range on Protein: 35-92
Range on HMM: 88-144/305.0
RSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQgQDEPEVMF
. .| || || .||  || | .... . |.|| . .|.| .||. |..  .|.... |
krfictqaplektcadfwymclqdkveaifmlcnllekgakkcleyfas.kdkdvlef

subfamily_eak_pd Subfamily eak 29-101 9.2e-11 35.7 In-house 87-158 (332) alignment
Range on Protein: 29-101
Range on HMM: 87-158/332.0
QVEEVKRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQGQDEpEVMFGRYRIELIS
.  || | ||||  .       ||||| ||.   |..| . .| ...|   |.|.   | |. || . .|  .
efsevGrkyiltGiasedkvfafwqmvleqkspaivqlledvelkleksdkyfpdktre.elkfGildverke

subfamily_Urchin-PTP-4_pd Subfamily Urchin-PTP-4 33-165 1.4e-10 35.2 In-house 86-238 (392) alignment
Range on Protein: 33-165
Range on HMM: 86-238/392.0
VKRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIE--RG--MNKCYPY----WPQGQ------------DEPEVMFGRYRIELISIEDYSFFRLSH
 ...|| .||| . . | ||.||...|   | |..|  |  .|  .. .  .    ||. .             | .. ||.|   ||        |   
nekayiasqgpnaaslddfwrmvfqenvttiamvtklkegdkgddartvaqfhftewPdkdvpkhtssllkfikevkadfGqythpliihcsagvgrtgv

LQLENVEIEDTDDYNSVEIQEVLLNMRKQRLGLIQTPDQLRFSYVAILQRIWK
.   .  .  .     |.. ... |.|..|  ..|| .|  | | |.|. .  
visidsvvahakktrmvdvfnfvtnirrkrpymvqtkeqyafiygavledllw

subfamily_Fungi-PTP2_pd Subfamily Fungi-PTP2 33-85 2.9e-10 34.0 In-house 105-157 (349) alignment
Range on Protein: 33-85
Range on HMM: 105-157/349.0
VKRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQGQ
|.. || || ||| | | |....  .. | .| ||.  | ...||. || ...
vekkyiatqaPlPstvddfykvillngvklvlsLnddkelslekcdiywqels

0044763 (Phosphotyrosine protein) phosphatases II 33-154 3.4e-10 35.3 In-house 26-162 (178) alignment
Range on Protein: 33-154
Range on HMM: 26-162/178.0
VKRSYILTQGPLphtcDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQGQDepevmfgrYRIELISIEDYSFFRLSHLQLENVEIEDTDD-------
.   ..|.. |      .......|.... |..|.. .|.| .||.||||.. .        ..   | |.|.. . |.   || ||. ..         
ilpglylgslpp....addlellkelgithivnlteelelgflkcdpywpeeag........iqylhipipDhgvpdllehflefvefieealdekggpv

---------------------YNSVEIQEVLLNMRKQRLgLIQTPDQLRF
                     .... ..|..  .|..|   ...|.|||.
lVHCsaGvgRsgtlvaaylmkklglsleeaielvrerRp.ivpnpgqlrq

subfamily_Sponge-PTP6_pd Subfamily Sponge-PTP6 35-86 4.9e-10 33.4 In-house 91-137 (439) alignment
Range on Protein: 35-86
Range on HMM: 91-137/439.0
RSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMnkcypYWPQGQD
. || ||||  .|.|.||..|.|...  |.|| . .|        |||  ..
klyiatqgpkkettddfwrlviekktvtivmltnlvesyk.....ywpsdae

subfamily_Cele-PTP-8_pd Subfamily Cele-PTP-8 28-85 6.7e-10 33.5 In-house 75-132 (288) alignment
Range on Protein: 28-85
Range on HMM: 75-132/288.0
FQVEEVKRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQGQ
.  .. ||  | .| ||  | . .|.|. |.. . |.||.. .|.| .|   |.|  .
vssakykrrlicaqaPlngtieelWkmllesdveyivmlcellekGkeksaeyfPskl

0049772 (Phosphotyrosine protein) phosphatases II 35-163 8.2e-10 34.4 In-house 84-280 (314) alignment
Range on Protein: 35-163
Range on HMM: 84-280/314.0
RSYILTQGPLPHTCDHF----------WQMV--WEQNCKGILM---------------------LNKCIERGmnkcypywpqgQ-----DEPEVMfgryr
...| |||||..|.. |          |.||  ...|.  | |                     |... ..|                 | ..       
lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivmsrdevladelsrLdaAlgKtpllildgng...........neptaadlellk.....

ielisiEDY---SFFRLSHLQLENVEIEDtDDYN---------------------------------------------SVEIQEVLLNMRKQRL-----
      | .   ..|   .... .. ..| .. .                                              | ..|.|  .|..|      
......eelydpelferlgikylripvpD.gsaplledfdeflefieeadkggpvlvHCkaGkgRtgtfvvaaylmkllgvsleealedvrlkRpinpnp

GLIQTPDQLRFSYVAILQRI
|.|....|. | . |.|...
gfieqleqyefilealleyl

subfamily_Nvec-PTP-1_pd Subfamily Nvec-PTP-1 33-85 2.9e-09 31.5 In-house 49-101 (239) alignment
Range on Protein: 33-85
Range on HMM: 49-101/239.0
VKRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQGQ
  ..|| ||| .  ..  ||.|.|..    |.||   ||   .||. |||.  
spkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdst

subfamily_Anemone-PTP-1_pd Subfamily Anemone-PTP-1 33-84 3.3e-09 31.3 In-house 50-101 (239) alignment
Range on Protein: 33-84
Range on HMM: 50-101/239.0
VKRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQG
  ..|| ||| .  ..  ||.|.|..    |.||   ||   .||. |||. 
spkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpds

subfamily_Cele-PTP-16_pd Subfamily Cele-PTP-16 24-68 2.3e-08 28.0 In-house 72-116 (303) alignment
Range on Protein: 24-68
Range on HMM: 72-116/303.0
WHPLFQVEEVKRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNK
 |  .   . ..  |||| ||.||.  ||||. ||. | .|.|  
ihasyleldsskkailtqlplshtaadfwqmiieqkvkcvllllt

subfamily_Sponge-PTP1_pd Subfamily Sponge-PTP1 33-84 2.6e-08 28.2 In-house 70-120 (267) alignment
Range on Protein: 33-84
Range on HMM: 70-120/267.0
VKRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPywPQ-G
 |. .|.||.||  |  .|.... .|..  | .| |  .  ... .|  |. |
tknafivtqdplkntitdfltvihdqkvpvivlltkvftdnirlfwP..Pkmg

subfamily_Anemone-PTP-3_pd Subfamily Anemone-PTP-3 34-85 3.9e-08 27.7 In-house 4-55 (199) alignment
Range on Protein: 34-85
Range on HMM: 4-55/199.0
KRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGmNKCYP-YWPQGQ
.| || || || .|   |||||||     |.|.|       .  || |||  .
qrryiatqhplretmadfwqmvwetgsghivmvnddqknk.eadypfywptte

subfamily_Nvec-PTP-3_pd Subfamily Nvec-PTP-3 34-85 4.5e-08 27.5 In-house 3-54 (198) alignment
Range on Protein: 34-85
Range on HMM: 3-54/198.0
KRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMnKCYP-YWPQGQ
.| || || || .|   |||||||     |.|.|          || |||  .
qrryiatqhplretladfwqmvwetgsghivmvnddqknke.adypfywptte

subfamily_Cele-PTP-11_pd Subfamily Cele-PTP-11 36-80 1.8e-07 25.2 In-house 83-127 (312) alignment
Range on Protein: 36-80
Range on HMM: 83-127/312.0
SYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPY
 .. |||||  || ||||..    .  |..|   .| | .||  |
rfvctqgplentcthfwqlalslgstsiillcgfvedgsekcaky

DSPc_SM00195 121-161 3.7e-07 25.1 In-house 220-260 (263) alignment
Range on Protein: 121-161
Range on HMM: 220-260/263.0
EDTDDYNSVEIQEVLLNMRKQRLGLIQTPDQLRFSYVAILQ
.  .... |.|.|.. ..|||| |..|| .|..| | |||.
skleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaile

PTPc_SM00194 121-161 3.7e-07 25.1 In-house 220-260 (263) alignment
Range on Protein: 121-161
Range on HMM: 220-260/263.0
EDTDDYNSVEIQEVLLNMRKQRLGLIQTPDQLRFSYVAILQ
.  .... |.|.|.. ..|||| |..|| .|..| | |||.
skleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaile

subfamily_PTPN12_pd Subfamily PTPN12 126-172 4.9e-07 23.9 In-house 240-286 (290) alignment
Range on Protein: 126-172
Range on HMM: 240-286/290.0
YNSVEIQEVLLNMRKQRLGLIQTPDQLRFSYVAILQRIWKRMADADD
 ..... ...|..||||  |.|| .| .. | |... . |...  ..
peeldvfdlvlelrkqraalvqtkeqyelvykavaelvqkeleiiee

subfamily_Cele-PTP-7_pd Subfamily Cele-PTP-7 30-120 1.3e-06 22.1 In-house 86-177 (302) alignment
Range on Protein: 30-120
Range on HMM: 86-177/302.0
VEEVKRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQGQDEpEVMFGRYRIELISIEDY--SFFRLSHLQLENVEI
 |...        |   |.. .| .. . |   .  | . .| . .|| .|. .  .. |. |||| .. .|...    |    ...| .|||
tekkekvskkpivpkkstlekhwalieqynvaivvqlcsfvedeekkcaeyysdkvgg.elkfgrytvktvsvktdleeftdkksfklytvei

subfamily_Cele-PTP-9_pd Subfamily Cele-PTP-9 32-89 1.4e-06 22.6 In-house 32-82 (255) alignment
Range on Protein: 32-89
Range on HMM: 32-82/255.0
EVKRSYILtqgplphTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQGQDEPE
. | .|.|       | |.|.|..  .. . . ||    | |..||  |.|  .||  
krknlysl.......tvdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdekl

subfamily_PTPN9_pd Subfamily PTPN9 120-161 1.7e-06 22.3 In-house 247-288 (297) alignment
Range on Protein: 120-161
Range on HMM: 247-288/297.0
IEDTDDYNSVEIQEVLLNMRKQRLGLIQTPDQLRFSYVAILQ
..  .. . |...|..  .|.||   ||||.|  | |.|.|.
lsrleevgtvdvvetvkllrtqrafsiqtpeqyefcylavle

subfamily_Urchin-PTP-2_pd Subfamily Urchin-PTP-2 32-98 3.6e-06 20.6 In-house 233-294 (440) alignment
Range on Protein: 32-98
Range on HMM: 233-294/440.0
EVKRSYILTQGPLPHTCDHFWQMVWEQNCKGILMLNKCIERgmnKCYPYWPQGQdePEVMFGRYRIE
  | ..| || ||  |   ||..| . .   |.|||.  ..    |  |||       | || . . 
skknafiatqmpldstvldfwrlvhdyristiimlnqlndk...tcsiywpvnt..rsvtfgpftvg

PTPc_DSPc_SM00012 123-160 4.4e-06 22.2 In-house 70-104 (105) alignment
Range on Protein: 123-160
Range on HMM: 70-104/105.0
TddyNSVEIQEVLLNMRKQRLGLIQTPDQLRFSYVAIL
|   ..|.|....  .|||| |..|| .|  | | |.|
t...kevdifqivkelrkqRpgmvqteeqylflyrall

subfamily_PTPN13_pd Subfamily PTPN13 127-161 4.4e-06 21.2 In-house 233-267 (273) alignment
Range on Protein: 127-161
Range on HMM: 233-267/273.0
NSVEIQEVLLNMRKQRLGLIQTPDQLRFSYVAILQ
......|.. ..|.|| |..|| ||  | | |||.
kefdvkeivrklreqrqgvvqtkdqyifvykaile

subfamily_hpo-7_pd Subfamily hpo-7 32-89 6.8e-06 20.2 In-house 35-88 (263) alignment
Range on Protein: 32-89
Range on HMM: 35-88/263.0
EVKRSYILtqgpLPHTCDHFWQMVWEQNCKGILMLNKCIERGMNKCYPYWPQGQDEPE
. | .|.|    |  | | |.|..  .. . . ||    | |..||  |.|  .||  
krknlysl....lvqtidkfyqtivqtktevvvmLcDfneegvekcssyfPlekdekq

Y_phosphatase Protein-tyrosine phosphatase 125-160 9.7e-06 20.5 Pfam-A 199-234 (235) alignment
Range on Protein: 125-160
Range on HMM: 199-234/235.0
DYNSVEIQEVLLNMRKQRLGLIQTPDQLRFSYVAIL
. ..|.. ... ..|||| |..|. .|. | | |||
aeeevdvlqivkelRkqRpgmvqsleqYiflykail

Y_phosphatase Protein-tyrosine phosphatase 125-160 9.7e-06 20.5 In-house 199-234 (235) alignment
Range on Protein: 125-160
Range on HMM: 199-234/235.0
DYNSVEIQEVLLNMRKQRLGLIQTPDQLRFSYVAIL
. ..|.. ... ..|||| |..|. .|. | | |||
aeeevdvlqivkelRkqRpgmvqsleqYiflykail