Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
| Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
|---|---|---|---|---|---|---|---|---|---|
| subfamily_PTPN6_pd | Subfamily PTPN6 | 209-529 | 7.9e-150 | 493.0 | In-house | 2-305 (306) | alignment | ||
Range on Protein: 209-529
Range on HMM: 2-305/306.0
TSFLPLNIKQRVSELEKqNQDMYGKAGFWEEFEQMQQQETRHLYSRKEGVKPENRPKNRFKNILPFDHTRVILKdgyDPDVPGSDYINANYISGETPDSD
||.|. .|.|||||||| ......||||.||||..||.|...|.||||| ||||. |||.|||||||||||||| .|.||||||||||||..|...||
tsllakeieqrvselek.eeeslekagfeeefeelqqeeakkllsrkegakpenkeknryknilPfDhtrvilk...epsvpgsdyinanyikkevkgsd
CEYIATQGCLPATVNDFWRMVWQEGSLVIVMITNEVERGRNKCSRYWPSPESPEEtYGLIHVTSLEEdTANSHYILRHFLVEKRapdapeedggdEGAYE
..||||||||..||.||||||||| | ||||.|.|||||..||.||||. |. || || |.||...| .....||||...|.|. . . |
ksyiatqgclettvsdFWrmvwqensrvivmttkevErgkekCarYWPdeeekee.yGkisvtnvse.ksladYilRelsvskk...........kkkke
SRHIFQFHFKAWPDHGVPQDPGVVLAFMQDVNMKVQQLRSLNPGPTVVHCSAGIGRTGTYIIIDVIIKLIESQGWDVDIDIQKSVQIARGQRSGMVQTEQ
.|..||.|||.|||||||.|||.||.|..|||.| ..|.. ..||.|||||||||||||.|.||...||||..|.|.||||||.|...| ||||.|||||
erevfqyhfksWPdhgvpkdpgavLdfledvnrkqeeleeaeagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqteq
QYKFVYRAILHYVEASTQLKQ
||||||.|| .|.|....|..
qykfvykaikkyietkkklee
|
|||||||||
| 0050432 | (Phosphotyrosine protein) phosphatases II | 205-522 | 6.8e-98 | 323.0 | In-house | 13-300 (308) | alignment | ||
Range on Protein: 205-522
Range on HMM: 13-300/308.0
PFHSTSFLPLNIKQRVSELEKQNQDMYGKAGFWEEFEQMQQQETrhLYSRKEGVKPENRPKNRFKNILPFDHTRVILkdgydpDvPGSDYINANYISGET
.|..||.|. ..|..| .| |. ...... ...||||..... . |.... . .|||..|||.|.|||.||.||.| | .|||||||.|..| .
lfrdtsilvsslklsvldllkllekaldlglleeefeellsvkp..lleysvallpenkdkNrykdilpydhsRVkl......d.egsdYInAsyvdgys
PDSDCEYIATQGCLPATVNDFWRMVWQEGSLVIVMITNEVERGRNKCSRYWPSPES-PEETYGLIHVTSLEEDTaNSHYILRHFLVEKRApdapeedggd
......|||||.|| ||.|||||||.... ||||.|..||.||.|| .|||. . ..|| ..|| |.|.. ...|..|.. ...
sklprkfIatqgPlpntvedFwrmvweqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseev.lddytvrtleltnlg..........
egAYESRHIFQFHFKAWPDHGVPQDPGVVLAFMQDVNMKVqqlrslNPGPTVVHCSAGIGRTGTYIIIDVIIKLIESQgwdVDIDIQKSVQIARGQRSGM
|||.. .||...|||||||..| .|.|.. |. . ..||.|||||||.|||||.|..|... ..| . .|... |. | || ||
..dgesrtvthfhytnWpdhgvPpspeilldflelvrksl......pggpivVHCsaGvGRtGtfialdllleqleke...ggvdvfeavkklReqRpgm
VQTEQQYKFVYRAILHYVE
|||..||.|.|||.|.|..
vqtpeqylflyralleylk
|
|||||||||
| subfamily_PTPRD_pd | Subfamily PTPRD | 223-525 | 7.9e-98 | 323.5 | In-house | 10-285 (564) | alignment | ||
Range on Protein: 223-525
Range on HMM: 10-285/564.0
LEKQNQDM--YGKAGFWEEFEQMQQQetrHLYSRKEGVKPENRPKNRFKNILPFDHTRVILKDGydPDVPGSDYINANYISGETpdSDCEYIATQGCLPA
|.. . . ... | ||....... . . .. ||.|..|||..||...||.||.|. . ..|||||||..| | . .. .|||||| |.
lkehvaklkansdlkfeeeykkieeg...qqftweaankpaNkaKNRyanivaYdhsRVvLskv..egdegsDYINAsfidgyr..krkayIAtqgPlae
TVNDFWRMVWQEGSLVIVMITNEVERGRNKCSRYWPSPeSpEETYGLIHVTsLEEDTANSHYILRHFLVEKRApdapeedggdegAYESRHIFQFHFKAW
|..|||||||.. | .|||.|. .|.|..||..|||. . .|||| ..|| ||| . ..|..|.| ..| ||| . |||| .|
tiedFWRmvweqnsstiVmltkleEkgkvkchkYWPek.g.tetygeltVt.leeeeeladyeirtfklkkkk............ssesreVrqFhFtsW
PDHGVPQDPGVVLAFMQDVNMKVQqlrsLNPGPTVVHCSAGIGRTGTYIIIDVIIKLIESqgwDVDIDIQKSVQIARGQRSGMVQTEQQYKFVYRAILHY
||||||. . .|.....|. . . ||.|||||||.|||||.|.||.... |.. . ..|| . |. | || |||||.|| |...|||..
PdhgvpesatslLdlirkvralne....pdagPivVhCSaGVGRTGtfividamlerike...ektvDiyqyvkalrkqRnamVqteeQYiFiheailea
VEAST
... .
lacgn
|
|||||||||
| 0046845 | (Phosphotyrosine protein) phosphatases II | 235-522 | 2.1e-94 | 311.4 | In-house | 1-275 (284) | alignment | ||
Range on Protein: 235-522
Range on HMM: 1-275/284.0
GFWEEFEQMQQQETRHLYSRKEGVKPENRPKNRFKNILPFDHTRVILKdGYDPDVPGSDYINANYISGETP---DSDCEYIATQGCLPATVNDFWRMVWQ
|..||||..... . .|.|.. ...|||. |||.|.|||.||.||.|| .|.|...||||||.|..| .. ...||||| || ||.|||||||.
gleeefeellsltvklllslsvallpenlsknRykdilpydhsRVklk.sldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvwe
EGSLVIVMITNEVERGRNKCSRYWPSPeSPEETYGLIHVTSLEEDTaNSHYILRHFLVEKRAPdapeedggdegAYESRHIFQFHFKAWPDHGVPQDPGV
... ||||.|..||.||.||..|||. . ||| ..|| |.|.. ...|..|.. ... . |||.. .||...|||||||..|
qnvrvIVmltelvengrekcaqYwple.gevltygdftvtllseev.kddytvrtleltnlgy...........tgesrtvthfhytswpdhgvppsped
VLAFMQDVNMKVQQlrSLNPGPTVVHCSAGIGRTGTYIIIDVIIKLIESQGWDVDIDIQKSVQIARGQRSGMVQTEQQYKFVYRAILHYVE
.|.|...|. .. . ..||.|||||||.|||||.|..|......| .|... .|... |. | || |||||..||.|||.|.|.|.
lleflrlvrellen..lpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleylk
|
|||||||||
| 0045450 | (Phosphotyrosine protein) phosphatases II | 221-521 | 8.6e-92 | 303.4 | In-house | 14-304 (307) | alignment | ||
Range on Protein: 221-521
Range on HMM: 14-304/307.0
SELEKQNQDMYGKAGFWEEFEQMQQQETRHLYSRKEGVKPENRPKNRFKNILPFDHTRVILKDGyDPDVPGSDYINANYISG------ETPDSDCEYIAT
..|... . ...|...|||.........|...... .|||..|||.|.|||.|||||.|.. |.....||||||.|. ...|.. ..|||
llllvllllldfltgllkefekllsvtvfllgeysiallpenkdknrykdilpydhtRVklssl.dgsledsdYiNAsyvrvpllllldgydlkrkfIat
QGCLPATVNDFWRMVWQEGSLVIVMITNEVERGRNKCSRYWPSPeSPEETYGLIHVTSLEEDTaNSHYILRHFLVEKRapdapeedggdEGAYESRHIFQ
||.|| ||.|||||.|..|. ||||.|..||.||.|| .|||. . | ||| ..|| |.|.. ..|..|.. |. .| |||.. .
qgPlpetvedFwrmlweqgvtvivmltelvelgrekcaqywPde.geeltygnftvtllseeh.ldgytvrtlevtdl...........dgtgesrtvth
FHFKAWPDHGVPQDPGVVLAFMQDVNMKVQQLrsLNPGPTVVHCSAGIGRTGTYIIIDVIIKLIESQGWDVDIDIQKSVQIARGQRSGMVQTEQQYKFVY
||...|||||||... .|.|.. |. ...| ..||..||||||.|||||.|.........|..|. |.|... |. | ||.|.||...||.|.|
fhytgwpdhgvppsfeelldfieevrkaleel..pkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrfly
RAILHYV
.|.|...
eallell
|
|||||||||
| 0036941 | (Phosphotyrosine protein) phosphatases II | 224-522 | 9.3e-92 | 302.8 | In-house | 3-278 (297) | alignment | ||
Range on Protein: 224-522
Range on HMM: 3-278/297.0
EKQNQDMYGKAGFWEEFEQMqqQETRHLYSRKEGVKPENRPKNRFKNILPFDHTRVILkdgydpDVPGSDYINANYIsgETPDSDCEYIATQGCLPATVN
.| .. ..|....|||.. .. .|.|.. . .|||..|||.|.|||.|||||.| | .|||||||.|. ...| . ..|||||.|| ||.
lkllekllflalllkefeel..lpllllgslsvallpenleknRykdilpydhtRVkl......ddegsdYinAsyv..dgydlkrkfIatqgPlpntve
DFWRMVWQEGSLVIVMITNEVERGRNKCSRYWPSPESPEETYGLIHVTSLEEDTA-NSHYILRHFLVEKRapdapeedggdeGAYESRHIFQFHFKAWPD
|||||||.... ||||.|..||.||.|| .|||. | . ||| ..|| |.... ...|.||.. |.. | |||.. .||.. |||
dFWrmvweqnvtvIvmltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdt............gngesrtvthfhytgwpd
HGVPQDPGVVLAFMQDVNMKVQQLrsLNPGPTVVHCSAGIGRTGTYIIIDVIIKLIESQGWDVDIDIQKSVQIARGQRSGMVQTEQQYKFVYRAILHYVE
||||..| .|.|.. |. . ..| ..||..||||||.||.||.|..|... ..|.. .|| . |. | || |.|||..||.|.|.|.|...
hgvpespaslldfielvrkvlkll..psggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallellk
|
|||||||||
| 0051299 | (Phosphotyrosine protein) phosphatases II | 230-521 | 1.4e-91 | 302.2 | In-house | 19-286 (288) | alignment | ||
Range on Protein: 230-521
Range on HMM: 19-286/288.0
MYGKAGFWEEFEQMQQQETRhlYSRKEGVKPENRPKNRFKNILPFDHTRVILKDGYDpdVPGSDYINANYISGetPDSDCEYIATQGCLPATVNDFWRMV
. |..|..||||..... . .... ...|||..|||...|||.||.||.|.. . |.|||||||.||.| .......|||||.|| ||.||||||
angltglleefeellsllpd..ltlsaallpenleknRysdilpydhsRVkLsvldg..vegsdYinAsyidg..ynlkrkfIatqgPlpntvedFWrmv
WQEGSLVIVMITNEVERGRNKCSRYWPSpeSPEETYGLIHVTSLEEDTaNSHYILRHFLVEKRAP-DapeedggdeGAYESRHIFQFHFKAWPDHGVPQD
|.... ||||.|..||.||.|| .|||. . .||| |.|| |.|.. ...|..|.. |.. | | |||.. .||...|||||||..
weqnvrvIvmltklvelgrekcaqYwpl..ggsltygditvtllseev.lddytvrtlevtnldlld.........gdgesrtvthfhytnwpdhgvpds
PGVVLAFMQDVNMKVQqlrsLNPGPTVVHCSAGIGRTGTYIIIDVIIKLIESQGwdvDIDIQKSVQIARGQRSGMVQTEQQYKFVYRAILHYV
| .|.|...|. . . ..||.|||||||.|||||.|..|... ..| .| .|. . |. | || |||||..||.|||.|.|.|.
pellldflrlvrkala....sgggpvvVHCsaGvgRtgtfialdllleqlekeg...gvdvleavkrlreqRpgmvqtpeqyrfvyealleyl
|
|||||||||
| DSPc_SM00195 | 236-521 | 1.9e-89 | 294.8 | In-house | 2-262 (263) | alignment | |||
Range on Protein: 236-521
Range on HMM: 2-262/263.0
FWEEFEQMQQQETRHlySRKEGVKPENRPKNRFKNILPFDHTRVILKDGYDPdvPGSDYINANYISGEtpDSDCEYIATQGCLPATVNDFWRMVWQEGSL
..||||....... . . .|. |..|. |||.|||||.|||||.||. .. .||||||||||.|. ... .||||||.|| ||.|||||||.|..
lkeefekleestspk..etteaekkknksknRyknilpydhtrVklkkeekk..egsdYINAnyikga..nkkkkyIatQgPlpstvedFWrmvweekvk
VIVMITNEVERGRNKCSRYWPSPESPEETYGLIHVTSLEEDTANSHYILRHFLVEKRAPdapeedggdegaYESRHIFQFHFKAWPDHGVPQDPGVVLAF
.|||.|.|.|.|..||.||||. . .||.| |.|. |... ....|||.. ..| .. |.| . |...|.|||||||... ||..
iivmlteeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegk............eetrkvtqyqyknWpdhgvpdstksvlel
MQDVNMKVQQLrslnPGPTVVHCSAGIGRTGTYIIIDVIIKLIESQGWdvdIDIQKSVQIARGQRSGMVQTEQQYKFVYRAILHYV
.. |. . .. ||.|||||||.|||||.. ||.|.. .|.. .||.. |. | || |||||..||.|.|.|||.|.
lravkksksts....sgpivVhCsaGvgRtgtfvtidiilskleeekk...vdifeivkelRkqRpgmvqtleqYlfiyeaileyi
|
|||||||||
| PTPc_SM00194 | 236-521 | 1.9e-89 | 294.8 | In-house | 2-262 (263) | alignment | |||
Range on Protein: 236-521
Range on HMM: 2-262/263.0
FWEEFEQMQQQETRHlySRKEGVKPENRPKNRFKNILPFDHTRVILKDGYDPdvPGSDYINANYISGEtpDSDCEYIATQGCLPATVNDFWRMVWQEGSL
..||||....... . . .|. |..|. |||.|||||.|||||.||. .. .||||||||||.|. ... .||||||.|| ||.|||||||.|..
lkeefekleestspk..etteaekkknksknRyknilpydhtrVklkkeekk..egsdYINAnyikga..nkkkkyIatQgPlpstvedFWrmvweekvk
VIVMITNEVERGRNKCSRYWPSPESPEETYGLIHVTSLEEDTANSHYILRHFLVEKRAPdapeedggdegaYESRHIFQFHFKAWPDHGVPQDPGVVLAF
.|||.|.|.|.|..||.||||. . .||.| |.|. |... ....|||.. ..| .. |.| . |...|.|||||||... ||..
iivmlteeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegk............eetrkvtqyqyknWpdhgvpdstksvlel
MQDVNMKVQQLrslnPGPTVVHCSAGIGRTGTYIIIDVIIKLIESQGWdvdIDIQKSVQIARGQRSGMVQTEQQYKFVYRAILHYV
.. |. . .. ||.|||||||.|||||.. ||.|.. .|.. .||.. |. | || |||||..||.|.|.|||.|.
lravkksksts....sgpivVhCsaGvgRtgtfvtidiilskleeekk...vdifeivkelRkqRpgmvqtleqYlfiyeaileyi
|
|||||||||
| 0047943 | (Phosphotyrosine protein) phosphatases II | 228-521 | 3.3e-89 | 294.3 | In-house | 6-272 (273) | alignment | ||
Range on Protein: 228-521
Range on HMM: 6-272/273.0
QDMYGKAGFWEEFEQMQQQETrhLYSRKEGVKPENRPKNRFKNILPFDHTRVILkdgydpDVPGSDYINANYIsgETPDSDCEYIATQGCLPATVNDFWR
... |.....||||..... . |.... ...|||. |||.|.|||.||.||.| . .|||||||.|. ..... ..||||| || ||.||||
ekllgltllleefelllslkp..lltysvallpenkdknrykdilpydhsrvkl......gdggsdyinAsyv..dgynlkrkfiatqgPlpntvedfwr
MVWQEGSLVIVMITNEVERGRNKCSRYWPSPESP-EETYGLIHVTSLEEDTaNSHYILRHFLVEKRApdapeedggdegAYESRHIFQFHFKAWPDHGVP
|||.... ||||.|..||.||.|| .|||. . ..||| ..|| |.|.| ...|..|.. ... |||.. .||.. |||||||
mvweqnvrviVmLtelvelgrekcaqYwpleggelsltygkftvtllseet.kddytvrtleltnlg............tgesrtvthfhytgwpdhgvp
QDPGVVLAFMQDVNMKVQQLRSLnpGPTVVHCSAGIGRTGTYIIIDVIIKLIESQGwdvDIDIQKSVQIARGQRSGMVQTEQQYKFVYRAILHYV
... .| |...|. . ..|.| ||.|||||||.|||||.|..|... ..| | .|. . |. | || |||||..||.|.|.|.|.|.
pslesllefielvrkalealpsn..gpvvVHCsaGvgRtgtfialdllldqlekeg...gvdvleavkllrsqRpgmvqtpeqyrflyealleyl
|
|||||||||
| 0040438 | (Phosphotyrosine protein) phosphatases II | 231-529 | 3.8e-89 | 294.4 | In-house | 15-284 (317) | alignment | ||
Range on Protein: 231-529
Range on HMM: 15-284/317.0
YGKAGFWEEFEQMQQQetrHLYSRKEGVKPENRPKNRFKNILPFDHTRVILKDgyDPDVPGSDYINANYIsgETPDSDCEYIATQGCLPATVNDFWRMVW
.. ...||||..... .|...... .|||..|||...|||.||.||.|.. .. ...||||||.|. ..|. ..|||||.|| ||.|||||||
sdftalleefedllsl...kldtysvaelpenkdknrypdilpydhsRVkLsp..lggdldsdYInAsyv..dgpnlkrkfIatqgPlpntvedFwrmvw
QEGSLVIVMITNEVERGRNKCSRYWPSpeSPEETYGLIHVTSLEEDTaNSHYILRHFLVEKRapdapeedG-GdegayESRHIFQFHFKAWPDHGVPQDP
..|. ||||.|...|.||.|| .|||. . ||| ..|| |.|.. .....||.. ||. | . |||.. .||...|||||||..|
eqgvtvivmLteleelgrekcaqYwpl..getltygdftvtllseee.lagitlrtlevedl........gds.....esrtvthfhytgWpdhgvppsp
GVVLAFMQDVNMKVQqlrsLNPGPTVVHCSAGIGRTGTYIIIDVIIKLIESQGwdvDIDIQKSVQIARGQRSGMVQTEQQYKFVYRAILHYVEASTQLKQ
.|.|.. |. . . ..||..||||||.|||||.|...... ..| | ..|... |. | ||.|.|||..||.|.|.|.|.|. .|.
dllldfleavreale....dpggpvlVHCsaGvgRtGtfiaaylmleqlekeg...gvdveeavkelreqRpgavqtpeqyrflydalleylkrkltlep
|
|||||||||
| subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 216-530 | 9.9e-89 | 292.5 | In-house | 7-289 (318) | alignment | ||
Range on Protein: 216-530
Range on HMM: 7-289/318.0
IKQRVSELEKqnqdmYGKAGFWEEFEQMQQQETrHLYSRKEgVKPENRPKNRFKNILPFDHTRVILKDgyDPDVPGSDYINANYISGETpdSDCEYIATQ
....| .|.. |. . ||.|.....| . | | ..| |. |||. |||..||||| |.. ...|||||||||| | . .. .|||.|
leshvrrlre.....sGelllseeyerlsrsee.tvtslks.lepvnkaknryanilaydhtrvkLqm..legeegsDyinanyidGyr..rkkayiaaq
GCLPATVNDFWRMVWQEGSLVIVMITNEVERGRNKCSRYWPSPESpeETYGLIHVTsLEEDTANSHYILRHFLVEKRapdapeedggdeGAYESRHIFQF
. || |..|||||||. .| ||||.|.|.|||..|. ||||| .| ..|| ..|. |.|.. |.|.||.| |... . |||.. |.
aPlpetieDfWrmvWeqnsavivmltqeeergkakvhryWPskgs..rsygklvve.lkeevelsdyvlrefkvtrt............eeeesrqvrqy
HFKAWPDHGVPQDPGVVLAFMQDVNMkVQQlrSLNPGPTVVHCSAGIGRTGTYIIIDVIIKLIESQGWdvdIDIQKSVQIARGQRSGMVQTEQQYKFVYR
|. .|||.|||.... .|.....|. .|| . . ||.|||||||.||||..|..|.... |. .. .|. . |. | || |||||.||.|.|
hytsWpdegvpesgaslldlvrqvsk.aqq..ksgagpivvhCsaGvGrtGvfiavdillerikaeal...vDvfqtvkqlreqrnlmvqtedqyefiyd
AILHYVEASTQLKQA
..| .... . .|
vllealasgdtevda
|
|||||||||
| subfamily_PTPRB_pd | Subfamily PTPRB | 231-526 | 3.4e-85 | 280.6 | In-house | 22-290 (293) | alignment | ||
Range on Protein: 231-526
Range on HMM: 22-290/293.0
YGKAGFWEEFEQMQQQETRHlySRKEGVKPENRPKNRFKNILPFDHTRVILKDGYdpDVPGSDYINANYISGETpdSDCEYIATQGCLPATVNDFWRMVW
...| ||.|.... .. . . | ...|| |||..||||.||.|| |.. | .||||||||||.| . | |.||||| || ||.|||||||
dsdlrfseeyeelkavgkdq..avkaaelavnraknrytnilpydhsrvkLaalk..desgsDYinanyipgyn..sprefiatqGPlpetvddfWrmvw
QEGSLVIVMITNEVERGRNKCSRYWPSPESPEeTYGLIHVTSLEEdTANSHYILRHFLVEKrapdapeedggdegAYESRHIFQFHFKAWPDHGVPQDPG
.. | .|||.|. ||.|. || .|||. |.| .|| |.|| ..| . .....|....|| . |.|.. |.||..|||||||...
ekkssiivmltqlvekgkvkCeeYWPadeepv.lyGdikvtlvae.eeledwvirelkiek..............ekeerkvrqyhftsWpdhgvPektk
VVLAFMQDVNMKVQQlrSLNPGPTVVHCSAGIGRTGTYIIIDVIIKLIESQGWdvdIDIQKSVQIARGQRSGMVQTEQQYKFVYRAILHYVEASTQ
.|.|.. |. .... . . .|.|||||||.|||||.| .| ... ||.. . .|| |. | .| .||||.|| |.....|.... ...
tlldfvrtvreaiek..taskrPivvhCsaGvGRtGtfialdrllqaieeedy...vdifgivaelReeRnllvqtekqYifihqcvldllrkkee
|
|||||||||
| 0039614 | (Phosphotyrosine protein) phosphatases II | 207-521 | 4.9e-85 | 280.9 | In-house | 5-289 (297) | alignment | ||
Range on Protein: 207-521
Range on HMM: 5-289/297.0
HSTSFLPLNIKQRVSELEKQNQDMYGKAGFWEEFEQMQQQETrhlySRKEGVKPENRPKNRFKNILPFDHTRVILKDGYDPdVPGSDYINANYIsgETPD
..... . |. .| .| .. .. .| ....|||..... ..... .|||..|||.|.|||.||.||.||. . ...||||||.|. ...|
rdallesipiplsvldlllllekansktllllefeellslkp....dysiallpenkdknrykdilpydhsrvklkpedgv.dldsdYinAsyv..dgyd
S-DCEYIATQGCLPATVNDFWRMVWQEGSLVIVMITNEVERGRnKCSRYWPSPESpeeTYGLIHVTSLEEDTaNSHYILRHFLVEKraPDapeedggdeg
. ..|||||.|| ||.|||||||..|. ||||.|..||.|| || .|||. .. ||| ..|| |.... ...|..|.. |.. .
lltrkfIatqgPlpetvedFwrmvweqgvtvivmLtklvelgr.kcaqywpeegg...tygdftvtllkveh.ldgytvrtlevtn..ng..........
ayESRHIFQFHFKAWPDHGVPQDPGVVLAFMQDVNMKVQQLrsLNPGPTVVHCSAGIGRTGTYIIIDVIIKLIESQgwdVDIDIQKSVQIARGQRSGMVQ
|||.. .|.. |||||||... ..| |.. |. ...| ..||..||||||.|||||.|... .. ..|. ..|... |. | ||.|.||
..esrtvthfqytgwpdhgvppslellleflelvrealael..pkggpvlVHCsaGvgRtGtfiaaylmleqleke...ggvdvleavkelreqRpgavq
TEQQYKFVYRAILHYV
|..||.|.|.|.|...
tpsqyrflydallell
|
|||||||||
| 0043336 | (Phosphotyrosine protein) phosphatases II | 229-521 | 2e-84 | 278.6 | In-house | 15-277 (278) | alignment | ||
Range on Protein: 229-521
Range on HMM: 15-277/278.0
DMYGKAGFWEEFEQMQQQETrhlYSRKEGVKPENRPKNRFKNILPFDHTRVILKDgyDPDVPGSDYINANYIsgETPDSDCEYIATQGCLPATVNDFWRM
. .|.....|||..... . .... . .|||..|||.|.|||.||.||.|.. .. ...||||||.|. .... ..|||||.|| ||.|||||
llnlktllllefeellsfkl...dtysiallpenkdknrykdilpydhsrvklsl..lggdldsdYinAsyv..dgynvprkfiatqgPlpetvedFwrm
VWQEGSLVIVMITNEVERGRNKCSRYWPspeSPEETYGLIHVTSLEEDTaNSHYILRHFLVEKRAPDapeedggdegayESRHIFQFHFKAWPDHGVPQD
||..|. .|||.|..||.||.|| .||| . .||| ..|| |.|.. ...|..|.. |... . |||.. ..|...||||||| .
vwelgvttivmLtelvelgrvkcaqYwp...ggsltygdftvtllkeeh.lddytvrtlevtnlgdg............esrtvthyhylgwpdhgvpes
PGVVLAFMQDVNMKVQqlrsLNPGPTVVHCSAGIGRTGTYIIIDVIIKLIESQGwdvDIDIQKSVQIARGQRSGMVQTEQQYKFVYRAILHYV
. .| |...|. ... ..||..||||||.|||||.|...... ..|. | .|... |. | || |.|||..||.|.|.|.|.|.
lsllldflkavreale....dsngpvlVHCsaGvgRTGtfialyllleqlekeg...gvdleeavkelreqRpgavqtpsqyrflyealleyl
|
|||||||||
| subfamily_PTPN12_pd | Subfamily PTPN12 | 229-527 | 3.7e-84 | 277.0 | In-house | 3-283 (290) | alignment | ||
Range on Protein: 229-527
Range on HMM: 3-283/290.0
DMYGKAGFWEEFEQMQQQETR----HLYSRKEGVKPENRPKNRFKNILPFDHTRVILKDGYDPDvpGSDYINANYISGetPDSDCEYIATQGCLPATVND
. .|.. | .||......... . ||...| |.||. |||.|.|||.|..|| |. . . ||||||||.| | .....||||.|| ||.|..|
ekegeeefakefqklkklsekykaekvysteagekeenvkknrykDilPydksrvelskieeee..gsdYinanfikg..vegkleyiaaqgPLpktldd
FWRMVWQEGSLVIVMITNEVERGRNKCSRYWPSPESPEETYGLIHVTSLEEDTANSHYILRHFLVEKRapdapeedggdegaYESRHIFQFHFKAWPDHG
||||.|. ..||. .||| |..|| ||||. | ..| ..|| ||.. . ...| . ||.. |||.. |||..||||||
fWrmiweknveivvmaCrevelgkkkCerYWpeegeeelefgefevtleeekavdddflirtLkveaq..............kesrkvyqfhYtaWPDhg
VPQDPGVVLAFMQDVNMKVQqlrsLNPGPTVVHCSAGIGRTGTYIIIDVIIKLIESQGWDVDIDIQKSVQIARGQRSGMVQTEQQYKFVYRAILHYVEAS
||. . .|.....|. . . | |||||||.||||| | || . .|.... . ..|. . |. | ||. .|||..||..||.|....|...
vPssaksllelielvrelqe....sedaPlvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelvqke
TQL
.
lei
|
|||||||||
| subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 220-525 | 6e-82 | 270.3 | In-house | 14-287 (319) | alignment | ||
Range on Protein: 220-525
Range on HMM: 14-287/319.0
VSELEKqnqdmYGKAGFWEEFEQMQQQETRhlySRKEGVKPENRPKNRFKNILPFDHTRVILKDGydPDVPGSDYINANYISGEtpDSDCEYIATQGCLP
. .|.. |. .. .||..... .. . .. |.||..|||..|||..|.|||.|.. ..|.|||||||..| | . ..||||. |
lkalas.....tgetllekefkllkeavnd...tfdsaskeenkkknryqnilaydrtrvvlsel..dgvegsdyinasfidgy..qerekfiatqaPle
ATVNDFWRMVWQEGSLVIVMITNEVERGRNKCSRYWPSPEspEETYGLIHVTSLEEDtANSHYILRHFLVEKRAPDApeedggdegayESRHIFQFHFKA
|..|||||||.|.| ..||.|. ||... |...|||. . |.|| . || .||. ..|| |.. ..|.. . |.|....|....
ntiedfWrmvWeeessivvmltklveklkvklkkywpeen..feeyGrlivtleeee.eledyiirklklnkkssev...........etRevkhfqyte
WPDHGVPQDPGVVLAFMQDVNMKVQQLRSlnpGPTVVHCSAGIGRTGTYIIIDVIIKLIESQGWdvdIDIQKSVQIARGQRSGMVQTEQQYKFVYRAILH
||||.||.. .|....... ... | || |||||||.|||||.|..|... .. .| .|. . |. | || |||...||||.| |.|.
WpdhdvPekatslldllkrirksrektqs...gPivvhCsaGvGRtGtfivldamlervkeegv...lDvfstvsrlRtqRnimvqrpeqYkfiyealle
YVEAST
.|||
aveagd
|
|||||||||
| Y_phosphatase | Protein-tyrosine phosphatase | 262-518 | 3.9e-78 | 257.5 | Pfam-A | 1-234 (235) | alignment | ||
Range on Protein: 262-518
Range on HMM: 1-234/235.0
NRPKNRFKNILPFDHTRVILkdgydPDVPG-SDYINANYISGETpDsDCEYIATQGCLPATVNDFWRMVWQEGSLVIVMITNEVERGRNKCSRYWPSPES
|. |||.|.|||.|.||| | . .| ||||||||..| . . . ..|||||.|. |..||||||||| . ||||.|...|.||.||..|||. |.
nkkknRykdilpydktrvkl.....kgsegpsdYInAnyvkgyk.e.kkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeee
PEETYGLIHVTSL-EEDTANSHYILRHFLVEKRAPDApeedggdegayESRHIFQFHFKAWPDHGVPQDPGVVLAFMQDVNMKVqqlrSLNPGPTVVHCS
..||| |.|. .| .....|.||.. ..|.. . |.|.. |.|...|||||||..| .| ....|. . . . ||.|||||
esltygdikvelkekekedekeytlrklelkkkkees...........ekrevkqlhytnWpdhgvpespkslldlirkveksk....eaksgpvvVhCs
AGIGRTGTYIIIDVIIKLIESQGWdvdIDIQKSVQIARGQRSGMVQTEQQYKFVYRAIL
||.|||||.. .|.... .|... .|. . |. | || ||||...||.|.|.|||
aGvgRtgtfvaldilleqleaeee...vdvlqivkelRkqRpgmvqsleqYiflykail
|
|||||||||
| Y_phosphatase | Protein-tyrosine phosphatase | 262-518 | 3.9e-78 | 257.5 | In-house | 1-234 (235) | alignment | ||
Range on Protein: 262-518
Range on HMM: 1-234/235.0
NRPKNRFKNILPFDHTRVILkdgydPDVPG-SDYINANYISGETpDsDCEYIATQGCLPATVNDFWRMVWQEGSLVIVMITNEVERGRNKCSRYWPSPES
|. |||.|.|||.|.||| | . .| ||||||||..| . . . ..|||||.|. |..||||||||| . ||||.|...|.||.||..|||. |.
nkkknRykdilpydktrvkl.....kgsegpsdYInAnyvkgyk.e.kkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeee
PEETYGLIHVTSL-EEDTANSHYILRHFLVEKRAPDApeedggdegayESRHIFQFHFKAWPDHGVPQDPGVVLAFMQDVNMKVqqlrSLNPGPTVVHCS
..||| |.|. .| .....|.||.. ..|.. . |.|.. |.|...|||||||..| .| ....|. . . . ||.|||||
esltygdikvelkekekedekeytlrklelkkkkees...........ekrevkqlhytnWpdhgvpespkslldlirkveksk....eaksgpvvVhCs
AGIGRTGTYIIIDVIIKLIESQGWdvdIDIQKSVQIARGQRSGMVQTEQQYKFVYRAIL
||.|||||.. .|.... .|... .|. . |. | || ||||...||.|.|.|||
aGvgRtgtfvaldilleqleaeee...vdvlqivkelRkqRpgmvqsleqYiflykail
|
|||||||||
| subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 227-524 | 1.7e-77 | 255.3 | In-house | 14-282 (288) | alignment | ||
Range on Protein: 227-524
Range on HMM: 14-282/288.0
NQDMYGKAGFWEEFEQMQQQETRHlySRKEGVKPENRPKNRFKNILPFDHTRVILKDGydPDVPGSDYINANYISGETpdSDCEYIATQGCLPATVNDFW
... ...|| ||.... . | . | . | ...| .|||..||||.|..|| ||.. ....|.|||||.|| || .. .|||||| |..||||||
kksarnrtgfseeynsLaalektk..svtagrlavnakknRyrnilpyDekrvklkkl..eeeagaDYinasyidgek..kkkkyiatqgPladtvndfW
RMVWQEGSLVIVMITNEVERGRNKCSRYWPSPESPEeTYGLIHVTSLEEdTANSHYILRHFLVEkrapdapeedggdeGAYESRHIFQFHFKAWPDHGVP
..|... . |||.|. ||.|..|| .|||. . |. || . || .|. ...||..|.| . ..| |....||||||||
elvyenktstivmltelveggktkCeeYWPdadkpk.nyGsvtvtlves.keledfvlrkllle..............kkkteleitqyqylaWpdhgvP
QDPGVVLAFMQDVNMKVQQLrslnPGPTVVHCSAGIGRTGTYIIIDVIIKLIESqgwDVDIDIQKSVQIARGQRSGMVQTEQQYKFVYRAILHYVEAS
.. .|.... |.. |. || .||||||.|||||.| .| .|. .|. . ||. |. | || .|||..|| |.|...|. .|.
eskapllellrqvkvanqad....tgpiivhCsaGvGrtgtFialdalidavee...edyiDvagtvaklRkqRallvqtlkqYefiyevllslieed
|
|||||||||
| 0045098 | (Phosphotyrosine protein) phosphatases II | 250-522 | 1.7e-77 | 255.8 | In-house | 21-273 (278) | alignment | ||
Range on Protein: 250-522
Range on HMM: 21-273/278.0
HLYSRKEGVKPENRPKNRFKNILPFDHTRVIlkdgydpdvpgsDYINANYISGEtpdsDCEYIATQGCLPATVNDFWRMVWQEGSLVIVMITNEVERGRN
. .. ......|..|||.|.|||.||.||. |||||.||.| . ..|||||.|| ||.|||||.|..|. ||||.|..||.||.
ipseitpalylgnldknRykdilpydhsrVk............dYINAsyidgy....pkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgre
KCSRYWPSpeSPEETYGLIHVTSLEEDTAnSHYILRHFLVEKRA----PdapeedggdegaYESRHIFQFHFKAWPDHGVPQDP--GVVLAFMQDVNMKV
|| .|||. . .||| ..|| |.|.. ..|.||..||. .|||.....|.. ||||||| .| .| ... .. .
kcaqywpe..ggsltygdftvtllseevl.ddytlrtllvtnltvered............lesrgvthlhylpwpdhgvpslpilksflellefireal
QQLRSL---------NPGPTVVHCSAGIGRTGTYIIIDVIIKLIesqgwDVDIDIQKSVQIARGQRSG-MVQTEQQYKFVYRAILHYVE
..| || ..||..||||||.|||||..... ...|. . .|... |. | || | .||...||.|.|...|....
kllaslllsslllldsggpvlVHCsaGvgRtGtlvaaylmlell.....eggvdlleavkelrsqRpglavqnleqyrflyefllelll
|
|||||||||
| 0040439 | (Phosphotyrosine protein) phosphatases II | 254-521 | 1.1e-76 | 253.0 | In-house | 3-246 (249) | alignment | ||
Range on Protein: 254-521
Range on HMM: 3-246/249.0
RKEGVKPENRPKNRFKNILPFDHTRVILKDgyDPDVPGSDYINANYIsgETPDSDCEYIATQGCLPATVNDFWRMVWQEGSLVIVMITNEVERGRNKCSR
.... .|||..|||...|||.||.||.|.. |....||||||.|| ..... ..|||||.|| ||.|||||.|..|. ||||.|..||.||.|| .
ysvallpenkdknrypdilpydhsrvklsi..lpglflsdyinAsyi..dgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaq
YWPSpeSPEETYGLIHVTSLEEDTaNSHYILRHFLVEKRapdapeedggdeGAYESRHIFQFHFKAWPDHGVPQDPGVVLAFMQDVNMKVQQLrsLNPGP
|||. . . .|| ..|| |.... ...|..|.. ... . |||.. .... |||||||... .|.|.. |. ...| ..||
ywpl..ggsleygdftvtllsvev.kddytvrtleltnl............ydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleel..pkggp
TVVHCSAGIGRTGTYIIIDVIIKLIESQGWdvdIDIQKSVQIARGQRSGMVQTEQQYKFVYRAILHYV
..||||||.|||||.|... .. ..| . .|.. |. | ||.|.||...||.|.|.|.|...
vlVHCsaGvgRtGtfiaaylmleqlekelg...vdleeavkllrsqRpgavqnpeqyrflyeallell
|
|||||||||
| subfamily_PTPRA_pd | Subfamily PTPRA | 207-528 | 4.3e-76 | 250.9 | In-house | 7-303 (330) | alignment | ||
Range on Protein: 207-528
Range on HMM: 7-303/330.0
HSTSFLPLNIKQRVSELEKQNQDMygKAGFWEEFEQMQQQETRHLYsrKEGVKPENRPKNRFKNILPFDHTRVILKDgyDPDVPGSDYINANYISGETPD
. . || ... |.... | | |||. . . . . . | ||. |||. ||||.|..|||| |. |||||| .| |
gnkkyfplpvekleeeirirsadd..nklfreefnalPagpiqatl..elaskeenkeknrvvnilPydfsrvilsv..keGveesdyinasfidGykek
SdcEYIATQGCLPATVNDFWRMVWQEGSLVIVMITNEVERGRNKCSRYWPSPESpeETYGLIHVtSLEEDTANSHYILRHFLVEkRAPDAPEEDggdega
..||.|| . ||.|||||.|. | |||.|. || ..|| .|||. . ||| |.| ..|..| .| .|.|||. . ||| .|.
d..kfiaaqGPkeetvedfwrmiweqksativmltelkerkeekcaqywPdeGl..vtyGnirv.evedetvlvdytvrkflvq.qlpdatrek......
yESRHIFQFHFKAWPDHGVPQDPGVVLAFMQDVnmkvQQLRSLNPGPTVVHCSAGIGRTGTYIIIDVIIKLIESQGwdvDIDIQKSVQIARGQRSGMVQT
.|| . ||||..||| ||| .| .| ... | ..|. . || |||||||.|||||.|..| ... ..... .|. . |. | ||. ||||
.ksrlvrqfhftswPdvGvPfepiGmlkllkkv....kklnqqsagpivvhcsaGvGrtGtfivldavlervkaer...kvdvfefvkrlrlqrpqmvqt
EQQYKFVYRAILHY-VEASTQLK
..||.|.|...|.| . . |.|.
deqyefiykvlleyylygdteld
|
|||||||||
| subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 228-523 | 3.5e-75 | 247.7 | In-house | 9-278 (281) | alignment | ||
Range on Protein: 228-523
Range on HMM: 9-278/281.0
QDMYGKAGFWEEFEQMQQQETRHlySRKEGVKPENRPKNRFKNILPFDHTRVILKDgyDPDVPGSDYINANYISGETpdSDCEYIATQGCLPATVNDFWR
.. .||| ||.|.... .... . . ..||. |||..|| .|.||| ... . . .||||||...| . .. ||||||| .||....||.
lsqndnaGfieeyeklaaigvdn..tataskadenvlknrYsnivaYDatrvkvtp..neenkntDYinanfvpgyk..gekeyiatqgPvPaslvafWq
MVWQEGSLVIVMITNEVERGRNKCSRYWPSPESpEETYGLIHVTSLEEdTANSHYILRHFLVEKRapdapeeDGgdegayESRHIFQFHFKAWPDHGVPQ
|||.. .|||.|.|.| |. || |||| ..| | .|| ..|.|..| .....|| |.| .|.. .| |.|.. |....||||||||.
mvweqkvsaivmvtreieagklkChrYWPddns.elkygdvtvkstae.eekatyierkfklere.......sg......etreveqlaytaWPdhGvPa
DPGVVLAFMQDVNmKVQQLRSLnpGPTVVHCSAGIGRTGTYIIIDVIIKLIESQGWDvdIDIQKSVQIARGQRSGMVQTEQQYKFVYRAILHYVEA
.. .| | ..|. |... .. | |.|||||.||||||| .| ..| .|.. . .|.. |. | .| |||| ||.|||.|.|....
ttkellefrkevl.kltekktk..aplvihCsaGvGrtGtyialDrlvkaveaelee..ldvkavvaelrkernlmvqtvvqyefvykavldaldk
|
|||||||||
| 0042113 | (Phosphotyrosine protein) phosphatases II | 257-521 | 1.5e-74 | 245.8 | In-house | 4-243 (245) | alignment | ||
Range on Protein: 257-521
Range on HMM: 4-243/245.0
GVKPENRPKNRFKNILPFDHTRVILKdgYDPDVPGSDYINANYIsgETPDSDCEYIATQGCLPATVNDFWRMVWQEGSLVIVMITNEVERGRNKCSRYWP
. .|||..|||...|||.|||||.|. |. ..||||||.|. ... .||||| || ||.|||||.|..|. .|||.|.|.|.||.|| .|||
allpenkdknrysdilpydhtrvkls..pdggdldsdyinasyv..dgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywp
SpeSPEETYGLIHVTSLEEDTaNSHYILRHFLVEKRapdapeedggdeGAYESRHIFQFHFKAWPDHGVPQDPGVVLAFMQDVNMKVQQlrsLNPGPTVV
. . . ||| ..|| |.|.. ...|..|.. |.. | .|||.....|. ||||||| .. .| |.. |. ... ..||..|
l..gesltygdftvtllseeh.lddytvrtlevtnl............gddesrevihyhylpwpdhgvpdllellldflefvrkalae...dsngpvlV
HCSAGIGRTGTYIIIDVIIKLIESQGwdvDIDIQKSVQIARGQRSGMVQTEQQYKFVYRAILHYV
|||||.|||||.|... .. ..|. . ...... |. | ||.|.|||..||.|.|.|.|...
HCsaGvgRtGtfiaaylmleqlekel...gvsleeavkelrsqRpgavqtpsqyrflyeallell
|
|||||||||
| 0037934 | (Phosphotyrosine protein) phosphatases II | 257-520 | 2.1e-74 | 245.4 | In-house | 5-241 (243) | alignment | ||
Range on Protein: 257-520
Range on HMM: 5-241/243.0
GVKPENRPKNRFKNILPFDHTRVILkdgydpdvPGSDYINANYISGEtPdsdcEYIATQGCLPATVND----FWRMVWQEGSLVIVMITNEVERGRNKCS
. .|||..|||...|||.||.||.| .||||||||.| . | .||||| || ||.| ||||.|..|. ||||.|..||.||.||
allpenlsknrysdilpydhsrvkl........egsdyinanliyvt.p....rliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekca
RYWPspesPEETYGLIHVTSLEEDTAnSHYILRHFLVEkrapdapeedggD-EGAYESRHIFQFHFKAWPDHGVPQDPGVVLAFMQDVNMKVQQL----R
.||| |.||| ..|| |.| . ..|..|..|.| . ...|.....|. .|||||||..| .|.|...|. ...|
qywp....gevtygdftvtllseehl.ddytvrtllle............nldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellslla
SLNPGPTVVHCSAGIGRTGTYIIIDVIIKLIesqgwdvDIDIQKSVQIARGQRSG-MVQTEQQYKFVYRAILHY
. ||..||||||.|||||.|.......|. ..|... |. | ||.| .|||..||.|.|.|.|..
ldsggpvlVHCsaGvgRtGtliaaylmllll.......gvdleeavkllreqRpgkavqtpsqyrflyeallel
|
|||||||||
| subfamily_PTPRG_pd | Subfamily PTPRG | 220-525 | 2.2e-74 | 245.7 | In-house | 3-291 (563) | alignment | ||
Range on Protein: 220-525
Range on HMM: 3-291/563.0
VSELEKQNQDMY--GKAGFWEEFEQMQQQETRHLYSRKEGVKPENRPKNRFKNILPFDHTRVILKDGydPDVPGS-DYINANYISGETpdSDCEYIATQG
|.|..| ... |. || ||||..|.. . . . ||||. ||| ||...|..|| |.. |.. .. |||||||| | ..|||||
vkefakhvaslhadgdigfseefealqsetiskdldaehsqkpenkrKnRylnivaydrsRvklspl..pgkkkklDYinAnyidGyq..kskafiatqg
CLPATVNDFWRMVWQEGSLVIVMITNEVERGRNKCSRYWPSpESPeETYGLIHVTSLEEDTaNSHYILRHFLVEKRAPDAPEEdggdegAYESRHIFQFH
|. |..|||||.|.. . .|||||| |||||.|| .|||. . . |||| ..|| ||.. . | |.. .... .. .. . . ... |.|
plkdtfddFWrmiWeqnvaiivmitnlvergrrkcdvYWPk.des.etygalqvtlieeev.lalytvrtlviknlklkkkkq......cdteklvrqyh
FKAWPDHGVPQDPGVVLAFMQDVnmkvQQLRSLNPGPTVVHCSAGIGRTGTYIIIDVIIKLIESQGwdvDIDIQKSVQIARGQRSGMVQTEQQYKFVYRA
. |||||||. . || |.. .. . . ||.|||||||.|||||||..| ..| |... ... . .. | || .|||| || |.. |
ytkWPdhgvPehslpvLifvkks....saankaeaGPivvHcsaGvgrtGtyivldtllkqiqqen...avnvfgflkhiraqRnflvqteEqYiflhda
ILHYVEAST
.| . .
lleaiaske
|
|||||||||
| subfamily_PTPN3_pd | Subfamily PTPN3 | 239-521 | 1.6e-73 | 242.1 | In-house | 20-275 (280) | alignment | ||
Range on Protein: 239-521
Range on HMM: 20-275/280.0
EFEQMQQQETRHlySRKEGVKPENRPKNRFKNILPFDHTRVILKDGYdpdvpgSDYINANYISGETPDSDC--EYIATQGCLPATVNDFWRMVWQEGSLV
.|||. ... . .. |||| .|||...|||.|.|||.||.. .|||||||.. | | .. |||||| |. |..|||.|||.. | .
qfeqlyrkkpgl..aisaarkpenlsknryrdilpydatrvklkese......tdyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqkssl
IVMITNEVERGRNKCSRYWPSPEsPEETYGLIHVTSLEEdTANSHYILRHFLVEKRApdapeedggdegAYESRHIFQFHFKAWPDHGVPQDPGVVLAFM
|||.|. ||||| || .|||..| | .|| ..|. .| ... |.||........ . |.|.|.|. . ||||||||.|. .| |.
ivmlttlverGrvkChqyWPete.deleygefsvkceke.detksyvlrelvlkdke............tkeerkilqlqylaWpdhgvPddsadflefv
QdvnmKVQQLRSLNPGPTVVHCSAGIGRTGTYIIIDVIIKLIESQGwdvDIDIQKSVQIARGQRSGMVQTEQQYKFVYRAILHYV
. .|..||| . |.|||||||||||| .|.... . |||.. .. . . |. | ||. .|||..||||| |||.
e....rvrklrsgkeePvvvhCsaGigrtGvlilletalalieaae...pvypldivrtmrdqramlvqtasqykfvCeailkvy
|
|||||||||
| subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 217-523 | 1.8e-72 | 239.1 | In-house | 11-292 (298) | alignment | ||
Range on Protein: 217-523
Range on HMM: 11-292/298.0
KQRVSELEKQNQDMyGKAGFWEEFEQMQQQET-RHLYSRKEGVKPENRPKNRFKNILPFDHTRVILKDGYdpDVPGSDYINANYISGETPDSdcEYIATQ
|. ...|.. .... . .|. .||..... . . . . . ||||. |||. .|...|..||.|.. . |||||| .... . . .||||
kaalqklaavkkkk.kltgyalefqrlnsvsseieeeekevarkpenkkkNRyadiialdssRvvLeked..adeesdYiNAsflhaykgrn..afiatq
GCLPATVNDFWRMVWQEGSLVIVMITNEVERGRNKCSRYWPSpeSPEETYGLIHVTSLeEDTANSHYILRHFLVEKRApdapeedggdEGayESRHIFQF
. |..||.||||||..| . .|||.|| .| .. |...|||. . .|||| |.|. | .. . .| |.. |.|. | ..|.. |.
aPltetvedFWrmvteedigtiVmltnleeldktkyhkywPd..egketygeitvsll.skeefadlivrklkvskkk..........ee..kerevrql
HFKAWPDHGVPQDPGVVLAFMQDVNMKVQQlrSlNPGPTVVHCSAGIGRTGTYIIIDVIIKLIESqgwDVDIDIQKSVQIARGQRSGMVQTEQQYKFVYR
|| |||.|||. ||.....|... || . | .|.||||.||.||.|.|| .. .. . .|. . |.. | .| |.||||.||.|.|
hftsWpdkgvpenatsvldllrkvrasqqq..a.gnkpvivqCsaGvgRsGtfiaidsvlervkk...eqvvDvfqvvkvlRkkrpgavqteeqYvfiye
AILHYVEA
|.|.....
avlealds
|
|||||||||
| subfamily_PTPN13_pd | Subfamily PTPN13 | 238-521 | 1.9e-71 | 235.5 | In-house | 15-269 (273) | alignment | ||
Range on Protein: 238-521
Range on HMM: 15-269/273.0
EEFEQMQqqETRHLYSRKEGVKPENRPKNRFKNILPFDHTRVILKDGYDpdvpgsdYINANYISGETPDSDCEYIATQGCLPATVNDFWRMVWQEGSLVI
|||.... | . | . ..| | ||. |||..|.||.|.|||.|.| ||||..| . . ||||.|| || ||.|||.|||. . ||
eefkelr..elkpldtcevgkkkenkdknryrnvlPydetrvklgdegg.......yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaevi
VMITNEVERGRNKCSRYWPSPE-SPEETYGLIHVTSLEeDTANSHYILRHFLVEkrapdapeedggDEGAYESRHIFQFHFKAWPDHGVPQDPGVVLAFM
.|.|.|.|.|. || ||||. . .. .. ..|. |. . . . .|.. |. | . |||.. ...| .|||||||. . .| |.
amvtlekekgkvkchrywPesknkklkvsnrlevellk.vqkldgfvvralavk............dsesgesrevahlnfvkwPdhgvPssaaellqfv
QDVnmkvQQLRSlNPGPTVVHCSAGIGRTGTYIIIDVIIKLIESQGwdvDIDIQKSVQIARGQRSGMVQTEQQYKFVYRAILHYV
. | ..|.. . || ||||||||||.||.| |||.. ||| . ..|... |. | || |.|||..|| |||.|||. .
aev....rrlqt.dagPivvhcsaGiGrsGtlitidvvlglierdk...efdvkeivrklreqrqgvvqtkdqyifvykailevl
|
|||||||||
| subfamily_PTPRK_pd | Subfamily PTPRK | 234-519 | 3.7e-71 | 234.5 | In-house | 22-275 (314) | alignment | ||
Range on Protein: 234-519
Range on HMM: 22-275/314.0
AGFWEEFEQMQQQetrhlysRKEGVKPENRPKNRFKNILPFDHTRVILKDgYDPDvPGSDYINANYISGETpdSDCEYIATQGCLPATVNDFWRMVWQEG
|| ||.| . . | ||| |||...||..|..||.|. | | | ||||||..| . . ..|.||| |. ||.||||.|..|.
ygfkeeyeslfeg.......wdaakkdenreknrsgdilaydrsrvflit.idgd.pssdyinaalidsyk..rpaafivtqgPlqetvkdfWrlvyden
SLVIVMITNEVERGRNKCSRYWPSPEspeETYGLIHVTSLEEDTaNSHYILRHFLVEKrapdapeedgGDEGAYESRHIFQFHFKAWPDHGVPQDPGVVL
. |||.|. || || ||..||| |.|| |.|. .| .. .. .. | | ||| | | | . ||.| .||||.||. .|
casivmltelvevgrvkClkyWPedt...evygdikvelvetel.laelvvrifrvek..........largqeeirevrqfqflgWpdhdvPvsatgll
AFMQDVNMKVQQlrslNPGPTVVHCSAGIGRTGTYIIIDVIIKLIESQGWdvdIDIQKSVQIARGQRSGMVQTEQQYKFVYRAILH
.... |... .. . |..||||||| |||||.|.||... .|| .| .|. . |. | ... ||.||.||||.| .||
klvrrvkksqee....eaGrivvhCsaGaGrtGtfiaidivldmieregv...vdvfnavktlrsrkvnmveteeqykfiydvile
|
|||||||||
| subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 257-523 | 3.3e-69 | 228.0 | In-house | 23-270 (274) | alignment | ||
Range on Protein: 257-523
Range on HMM: 23-270/274.0
GVKPENRPKNRFKNILPFDHTRVILKDGyDPDVPGSDYINANYISGETPDSDCeYIATQGCLPATVNDFWRMVWQEGSLVIVMITNEVERGRNKCSRYWP
. . |||.|.||| ...||.|. ... . |.||||||| | .| . |.|||| || ||.|||||..|| . ||||.|. |. ..||..|.|
ldvfgsqtknryktilPnensrvllese.ssededssyinanyikGydeeska.yvatqGPlpntvadfWrmiyqeevqvivmltklkeaneqkCavyfP
SPESP--EETYGLIHVTSLEeDTANSHYILRHFLVEKRAPdaPEEdggdegayesrhIFQFHFKAWPDHGVPQDPGVVLAFMQDVNMKvQQLRSLNPGPT
|. .|.|| .... . . . .| .|...... . . . . . .|||| .|.|. .| ....|. . .. .. . .|.
daedyeiserygdveikvek.iverndysvrklvlkyler..ers............vkhywytdWPdhksPddantlldlvlevees.reeenaklapv
VVHCSAGIGRTGTYIIIDVIIKLIESqgwDVDIDIQKSVQIARGQRSGMVQTEQQYKFVYRAILHYVEA
|||||||||||| .| |.. .. .. . .|. | | | .| |||||..||....||. .|..
vvhCsaGiGrtGcfiaisiavrqlre...eivvdvlkivcnlrldrGGmvqtseqyelihralclylkr
|
|||||||||
| subfamily_PTPN9_pd | Subfamily PTPN9 | 220-526 | 4.9e-69 | 227.6 | In-house | 3-295 (297) | alignment | ||
Range on Protein: 220-526
Range on HMM: 3-295/297.0
VSELEKQNQDMyGKAGFWEEFEQMQQQETRHLYSRKEgvKPENRPKNRFKNILPFDHTRVILKDgyDPDVPGSDYINANYISGETpdSDCEYIATQGCLP
..||.. ... || | .|......... . . . .. | |||....| .|.||| |. .. . |||||||.. | .||||| |.
ieelvayvkek.gkrGlskeyaeirnepveGtflask..lranleknrytdvlcydetrvvlak..vdedeasdyinanfvdGyk..qkkafiatqGplk
ATVNDFWRMVWQEGSLVIVMITNEVERGRNKCSRYWPSPESPEETYGLIHVTSLEEDTaNSHYILRHFLVEKRAPDapeedggdegayESRHIFQFHFKA
||.|||||||.. |||||.| ||||| ||..|||. | . .| ..|...| .. ...| | . ... . |||.. | | .
ktvsdfWrmvWeqevlvivmttrvvergrlkcgqyWpleeessaefgdlsvsnvevee.eedykvrvleiknvkte............esrkvthfqfls
WPDHGVPQDPGVVLAFMQDVNMK----VQQLR-----SLNPGPTVVHCSAGIGRTGTYIIIDVIIKLIESQGwdvDIDIQKSVQIARGQRSGMVQTEQQY
|||.|||.. .| ... | | |..| .. | |||||||||||||.| .|. .. .|..| .|....|. | ||. ..||..||
WPdyGvPssaaslldvlekvrekqalavkelgdewkghpsgPPivvhcsaGiGrtGtfitldiclsrleevg...tvdvvetvkllrtqrafsiqtpeqy
KFVYRAILHYVEASTQ
.| | |.| | ...
efcylavleyalelka
|
|||||||||
| subfamily_Ptp69D_pd | Subfamily Ptp69D | 221-524 | 8.8e-69 | 227.0 | In-house | 11-289 (307) | alignment | ||
Range on Protein: 221-524
Range on HMM: 11-289/307.0
SELEKQNQDMygKAGFWEEFEQMQQQETRHlySRKEGVKPENRPKNRFKNILPFDHTRVILKDGYDPDvpGSDYINANYISGEtpDSDCEYIATQGCLPA
..|.....| . |. .|.|.....|. . | | . | || |||...| .||.|||.|| . ||||||..| | . ..|| |. . |
ealksrkrdt..dfglakeyekLeareidk..stkvsekkenalknRyedikafDktRvkLkkingke..dsdYinasfikgy..kekkkfiaaqdPvea
TVNDFWRMVWQEGSLVIVMITNEVERGRNKCSRYWPSPesPEETYGLIHVTSLEEDTaNSHYILRHFLVEKRAPDAPEEdggdegaYESRHIFQFHFKAW
|..|||||... . .|||..|. | |.||..||| | || | |. .|.. |.|| |.. | | ...|. .||.. |.|...|
tigDfWRmiaeqevtlivmlsnlteknrkkcakYWpie..devqygdilvklvseek.hsdyiiReldvskkkeesgev.......edsrkvvqyhytgW
PDHGVPQDPGVVLAFMQDVNmkvqQLRSLNPGPTVVHCSAGIGRTGTYIIIDVIIKLIESqgwDVDIDIQKSVQIARGQRSGMVQTEQQYKFVYRAILHY
.| ||. . .| ... |. .| .|| .| ||||||| ||.|... .|.... .. . .|| . |. | ||. .|| .||.|.|||.| |
kDskvPevargllklieqvr....elyklnrsPivvhCsaGvgrsgifvaldsllqqlka...edkvdifetvkdLrsqRnllvqsleqYvflyralldy
VEAS
. .
ssyg
|
|||||||||
| subfamily_PTPN1_pd | Subfamily PTPN1 | 235-520 | 4.3e-68 | 224.1 | In-house | 6-270 (290) | alignment | ||
Range on Protein: 235-520
Range on HMM: 6-270/290.0
GFWEEFEQMQQQETRhLYSRKEGVKPENRPKNRFKNILPFDHTRVILKDGYDpdvpgsDYINANYIsgETPDSDCEYIATQGCLPATVNDFWRMVWQEGS
...|. . ..|.. .. .| .||||..||.... |.||.|..|... |||||. . | .. . .|| ||| || ||. ||.|||.. |
rlykeiyldirkeas.dfptreaklpenrnlnryrdvspydhsrikleradn......dyinaslv..eleeakrsyiltqGPlpntvdhfWqmvWeqks
LVIVMITNEVERGRNKCSRYWPSPES-PEETYG--LIHVTSLEEDTaNSHYILRHFLVEKrapdapeedggdEGAYESRHIFQFHFKAWPDHGVPQDPGV
.||. . ||....|| .|||. |. | .. ..|. ..|.. .|.|..|.. .|. . |.|.|..||. .||| |||. |.
kavvmlnkvvekeqikcaqywPqgeeekellledtklkvkliseer.ksyytvrllelen............lktqetreilhfhyttwpdfgvpespaa
VLAFMQDVNMKvQQLrSLNPGPTVVHCSAGIGRTGTYIIIDVIIKLIESQGWDVDIDIQKSVQIARGQRSGMVQTEQQYKFVYRAILHY
| |...| | | . ||.|.||||||||.||....| .. ||| .. .||.| . .| .| |..|| .| .| | |||.
flkflfkvres.Gsl.ssdvGpavihcsaGiGrsGtfclvdtclvliekkddlssvdikkvllelrkyrlGliqtadqlrfsylaileG
|
|||||||||
| subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 257-527 | 1.2e-66 | 219.5 | In-house | 4-248 (250) | alignment | ||
Range on Protein: 257-527
Range on HMM: 4-248/250.0
GVKPENRPKNRFKNILPFDHTRVILKDGYdPDvPGSDYINANYISGETPDsdCEYIATQGCLPATVNDFWRMVWQEGSLVIVMITNEVERGRNkCSRYWP
. ||.|. |||. .|...|..||.|. | |||||| .. | . .||||| |.||..||||||..| | .|||.|| .| ... ...|||
akkpqnkeknryadiialdssrvvLekek.gd.kesdyinasflhgyder..kafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqywP
SPESpeETYGLIHVTSLEEDTaNSHYILRHFLVEKRApdapEEdggdegayESRHIFQFHFKAWPDHGVPQDPGVVLAFMQDVNMKVQQLRSlnpGPTVV
.. |.|| ..|. |.... . |. |.. . |. .. ..|.. |.|| .||| |||. ||.....|. . || . .| .|
veka..ekyGdvtvsllskee.fadytkrklklskak....ka........derivrqlhfvvWPdkgvPevatavLellkkvqasqqqagn...aPviv
HCSAGIGRTGTYIIIDVIIKLIESqgwDVDIDIQKSVQIARGQRSGMVQTEQQYKFVYRAILHYVEASTQL
.||||.||.|..|.|| ... .. . .|. | ... | .| ..|....|| |||..||...... ..
qCsaGvgrsGafiaidavlerlkk...ekvvdvfkvikvlrkdrphavesleqyvfvyeiilkaldsvedy
|
|||||||||
| subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 262-524 | 6.9e-65 | 213.7 | In-house | 20-267 (270) | alignment | ||
Range on Protein: 262-524
Range on HMM: 20-267/270.0
NRPKNRFKNILPFDHTRVILKDGYDpdVPGSDYINANYISGETpDSDCEYIATQGCLPATVNDFWRMVWQEGSLVIVMITNEVERGRNKCSRYWPSPESP
.. ||...||| .|||.|.. . . . ||||||. | . .....|||..| ||.|...||||.|.| . |||.|. .|.||.||.||||.
gkklnRyadiLPsPatRvrleelee..dsataYinAnyvrGfd.gekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepke
--EETYGLIHVTSLEEdTANSHYILRHFLVEKrapdapeeDGgdegayESRHIFQFHFKAWPDHGVPQDPG------VVLAFMQDVNMKVQQLRSLNpgP
. ..| |.|..|.| . .. |||.. .|. .| |.|.. |....|||||||.... .|. ...| ..|. . |
kvkledgkikvlalse.ekeegyiltrlrlee........kg......eerrlvHfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkae..P
TVVHCSAGIGRTGTYIIIDVIIKLIESQGwdvDIDIQKSVQIARGQRSGMVQTEQQYKFVYRAILHYVEAS
..||||||.||||| |..| ...|.|... .|. . .. | .| .||. .||.|.|.|...|.|
llvHcsaGvgRtGtlialDiavrlLeetk...kvdvlaiieelRkdRmalvqhpeqyeflykavveyaerr
|
|||||||||
| subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 226-524 | 1.3e-64 | 213.3 | In-house | 14-286 (305) | alignment | ||
Range on Protein: 226-524
Range on HMM: 14-286/305.0
QNQDMYGKAGFWEEFEQMQQQETRHLYSRKEgvkpENRPKNRFKNILPFDHTRVILKDgyDPDVPGSDYINANYISGETpdSDCEYIATQGCLPATVNDF
... .| . |. .........|. .|| .|. |||.|.| ..|. |.||. ..... ||||||.|. | . .||..|| |. ||.||
kearvysdkgleaqykslyeeeesidvgkke....ankaknrlkeitlldddriilte..keslddsdyinasyvdgyk..rkkkyivaqgPlkntvadf
WRMVWQEGSLVIVMITNEVERGRNKCSRYWPSPESPEETYGLIHVTsLEEDTANSHYILRHFLVEKRAPdapeedggdegAYESRHIFQFHFKAWPDHGV
||....| .|||.|. || |..|| .||| .. .. .| ..|. |.. .. | || |.. . .. ||| . |... ||||||
WrliveekvstivmltklveggkdkCrqYWpesktekkefgefsve.lksektasdyieRklkisiede...........dkesrtvlqyqltdWPdhGv
PQDPGVVLAFMQDVNMKVQQLRslnPGPTVVHCSAGIGRTGTYIIIDVIIKLIESQGwdvDIDIQKSVQIARGQRSGMVQTEQQYKFVYRAILHYVEAS
|| .. .| ....|. . .. . | .||||||.||||..| .|. . .. . .|. . .. .| .| .|||| .|| |.. |. ....
pqfatsllslikrvqkdqkkdk...gvpllVhCsagvgRtGvfiavdialerlkkEe...vvdvfevlkqlRskrmkmvqtldqYvflhdaldelitcg
|
|||||||||
| subfamily_PTPN23_pd | Subfamily PTPN23 | 225-524 | 1.4e-64 | 212.7 | In-house | 6-283 (288) | alignment | ||
Range on Protein: 225-524
Range on HMM: 6-283/288.0
KQNQDMYGKAGFWEEFEQMQQQETRHLYSRKEGVKPENRPKNRFKNILPFDHTRVILKDGYDpdvpgsDYINANYISGETPDSDCeYIATQGCLPATVND
|.. . ||... ..|....|.. .. .| . . |||...|||.||.|| |... | ||||| .. . .| . . .||||. |. |.||
lqrkmldgktaldkkfkeleqkqdkearkrsiaiaklyseknrsrdilPyDhnRvklrgskD......DYinAsfvkdlspgcPd.fiatqaPlqstlnD
FWRMVWQEGSLVIVMITNEVERGRNKCSRYWPSPESPEETYGLIHVTsLEEDTANSHYILRHFLVEKRAPDApeedggdegAYESRHIfqfHFKAWPDHG
||.||... | ||||.... |.|..|..||||. . ...| ..|| |.. . .... |.. .| . .|| .. .|. ....||..|
FWlmvyeqkssviVmllskeelgkpkvdrYwPedkgetvkfgdlsvt.lksvretethvervlkletldada.........vksvshl...qltsWpelG
VPQDPGVVLAFMQDVNMKVQQLRSLNPGPTVVHCSAGIGRTGTYIIIDVIIKLIeSQGwDVDIDIQKSVQIARGQRSGMVQTEQQYKFVYRAILHYVEAS
||. |...|.|.. |. . .. . | |||||||.||||.. .. ... . ..| . .|| . |. | || |||...|.||.| |.|....
vPasPetllqfldevesayeavqrksktPlvvhCsaGvgRtgvfalvyaavrel.ekg.nglldiiqvvsrlreqRrfmvqekeqlkfsyeavleaarrv
|
|||||||||
| subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 231-519 | 4.4e-62 | 205.2 | In-house | 31-289 (319) | alignment | ||
Range on Protein: 231-519
Range on HMM: 31-289/319.0
YGKAGFWEEFEQMQQQETrHLYSRKEGVKPENRPKNRFKNILPFDHTRVILKDGYDpdVPGSDYINANYISGEtpDSDCEYIATQGCLPATVNDFWRMVW
. .. || .. .. . | .. ..|. |||. |||.||...| |. . .|||||| ...| . |||.|| |. |..|||||.|
ddltklevefrracklgv.nladqtfanldqnkdknriinilafdknvvklerliG..eefsdyinasfvtGy..qrkdkyiaaqGPldntladfWrmiw
QEGSLVIVMITnevergRNKCSRYWPSPESPEETYGLIHVTSLEEDTAnshYILRHFLVEKRApdaPEEDggdegayeSRHIFQFHFKAWPDHGVPQDPG
. . ||..| ..|||.||| .| . ..|.|.|| |..|.. . . . |.| |.| ||||. |||.|||. |
eyncstivllt......kdkcsqywplkivikeerfkvkvdsveetae...yvvrdielsedg...kekd........irkitqfhflGwpdvGvpdyps
VVLAFMQDVNMKVQQLRslNPGPTVVHCSAGIGRTGTYIIIDVIIKLIESqgwDVDIDIQKSVQIARGQRSGMVQTEQQYKFVYRAILH
.. ... |. .. . .. . |||||||.||||.||..||... .. . .|. . |. | ||. .|| ||||.| |.|
dlmrlvkkvrhltsken..hranivvhcsaGvGrtGvyivldvlldrmke...ekqvdvynfvrdlrqqrntlvqdlvqykfiysalle
|
|||||||||
| subfamily_PTPN14_pd | Subfamily PTPN14 | 233-524 | 6.7e-62 | 204.2 | In-house | 22-299 (300) | alignment | ||
Range on Protein: 233-524
Range on HMM: 22-299/300.0
KAGFWEEFEQMQQQETRHLYSrkEGVKPENRPKNRFKNILPFDHTRVILKDGYDPdvpGSDYINANYISGETPDSDCEYIATQGCLPATVNDFWRMVWQE
.. . |.|....... |.| . ||| .|||||..||....|| |. . ..|||| |. .. .||..|| |. ||.|||.|||..
egkvfteyeripkkredalls..taklpenaeknrfkdvlPyednrvelsptken...stgyinassikvsvggkersyivaqgPleltvqdfWqmvWeq
GSLVIVMITNEVERGRNKCSRYWPSPESPE--ETYGLIHVTSLEEDTAnSHYILRHFLVEKrAPdapeedggdegAYESRHIFQFHFKAWPDHGVPQDPG
| .|||.|.| | |..|. .|.|. || . ..| .||. ... . .| . . .. | . | | .. . .. |||||||.|.
gvqlivmlteeeedgkeksfkyfPkleskkktvefgkfkvttkfseds.dsvittglklkh.lp...........skeertvwhlqytDWpdhgvPeDvk
VVLAFMQDVNMKVQQLRSLNP-----GPTVVHCSAGIGRTGTYIIIDVIIKLIESqgwDVDIDIQKSVQIARGQRSGMVQTEQQYKFVYRAILHYVEAS
| ....|. .. | .. | .||||||.|||| |. |..|. .| . .|||.|.... | || .||| ||||||.....|.. |
gflsyLeevqsvrrktnseveskeskPPvlvhCsaGvGrtGvlilsdlliatleh...neeidikkvlarLreqrmllvqtlaqYkfvYkvlikylkns
|
|||||||||
| subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 227-523 | 1.2e-61 | 203.1 | In-house | 13-285 (290) | alignment | ||
Range on Protein: 227-523
Range on HMM: 13-285/290.0
NQDMYGKAGFWEEFEQMQQqeTRHLYSRKEGVKPENRPKNRFKNILPFDHTRVILKDG-YDPDVPgSDYINANYISGETpdSDCEYIATQGCLPATVNDF
|. . |. || ..|..... . . .. . |. ..|...|||.||.. | |..|.. ..| . .|||| || | . .|||||| .. |. ||
nghakgnegfrnqfkmlds..gesehtvtvgltssnkllnRfanivvyddnritLrpisghkDCt.neyinAcyikgyk..ekkqyiatqgpvsntlvdF
WRMVWQEGSLVIVMITNEVERGRNKCSRYWPSPesPEETYGLIHVTSLEEDTANsHYILRHFLVEKRAPDapEedggdegayESRHIFQFHFKAWPDHG-
|...||| . .|||.||..| |..|| |||. . ..|| .... |.| | | .|| |.. |... . . ..... |.....|...|
WkliwqekvtiivmltniieegkvkCqqYWpds..dtkaygefsikllneetln.eyierklevknknsa..g.........akqsvtqyqitnwdstgk
VPQDPGVVLAFMQdvnMKVQQLRSLnPGPTVVHCSAGIGRTGTYIIIDVIIKLIESQGwdvDIDIQKSVQIARGQRSGMVQTEQQYKFVYRAILHYVEA
|.. ...|.. . | .| .. .. |||||...||..... ... |. ...| ||. . .. | |. |.|||.|||..... .|.|..
vtnpqtillviee...myktqrkrg.ntsivvHCSdtvgrsavfcaaattinkckteg...vidvfqvlksqRiqkpgsvqtvqqyqgifqivltylds
|
|||||||||
| subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 235-522 | 4.1e-61 | 201.5 | In-house | 20-278 (315) | alignment | ||
Range on Protein: 235-522
Range on HMM: 20-278/315.0
GFWEEFEQMQQQEtrhLYSRKEGVKPENRPKNRFKNILPFDHTRVILKDgYDpDVPGSDYINANYISGEtpDSDCEYIATQGCLPATVNDFWRMVWQEGS
| ||| .. . . | .. . ...| .|||.|||||.|..||.|. | | | |||||| || . |.| |||.|| |.|.|.||||||.||
lfseefhdlpdPd...iyrqrvaretinfkknryknilPldsarvklev.id.dsPdsdyinasyiksv..dddkayiasqgPlkasvddfwrmvlqekv
LVIVMITNEVERGRNKCSRYWPSPESPEETYGLIHVTSLEEDTAnSHYILRHFlVEKRapdapeedgGDegayESRHIFQFHFKAWPDHGVPQDPGVVLA
|||.|. | . || .||| .. .| |.|. |. .. . . |.. | .. .. ||| . ||.|. |||.||... . .|
ttivmvtkkqegdkikcrqywPdrkadsvefGsikvellslead.tdgvarkl.vtrk.........se....esrtvtqfqftewPdkGvdkqtssllk
FMQDVNMKvqqlRSLNPGPTVVHCSAGIGRTGTYIIIDVIIKLIESQGwdvDIDIQKSVQIARGQRSGMVQTEQQYKFVYRAILHYVE
....| . . . . .||||||.|||| | || ... |. . .|. . |.. | .| .||||..| |.| |.| ..
likevkad....ngkkefsllvhcsaGvGrtGvvisidevvaqikrtr...svdvfnfvknlrakrpylvqteeeyafiydavledll
|
|||||||||
| subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 260-519 | 1.9e-60 | 199.7 | In-house | 23-253 (284) | alignment | ||
Range on Protein: 260-519
Range on HMM: 23-253/284.0
PENRPKNRFKNILPFDHTRVILKDGYDpdVPGSDYINANYISGEtpDSDCEYIATQGCLPATVNDFWRMVWQEGSLVIVMITnevergRNKCSRYWPSPE
..|. |||. .||.||...| |. . .|||||| .|.| . |||||| |. |..|||||.|. . ||..| ..|||.|||
dqnkdknrighilafdknvvklerliG..eefsdyinasfitGy..qrkdkyiatqGPldntladfWrmiweyncstivllt......kdkcsqywplki
SPEETYGLIHVTSLEEDTAnshYILRHFLVEKRApdaPEEdggdegayESRHIFQFHFKAWPDHGVPQDPGVVLAFMQDVNMKVQQLRslNPGPTVVHCS
.| . ..|.|.|| |..|.. . . . |. . |.| ||||. |||.|||. | ...... |. .. . .. . |||||
vikeerfkvkvdsveesee...yvvrdielsedg...kek........dirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltsken..hranivvhcs
AGIGRTGTYIIIDVIIKLIESqgwDVDIDIQKSVQIARGQRSGMVQTEQQYKFVYRAILH
||.||||.||..||... .. . .|. . |. | ||. .|| ||||.| |.|
agvgrtgvyivldvlldrmke...ekqvdvynfvrdlrqqrntlvqdlvqykfiysalle
|
|||||||||
| subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 224-526 | 1.3e-59 | 197.0 | In-house | 15-294 (325) | alignment | ||
Range on Protein: 224-526
Range on HMM: 15-294/325.0
EKQ-NQDmygKAGFWEEFEQMQQQETRhlySRKEGVKPENRPKNRFKNILPFDHTRVILKDGydPDVPGSDYINANYISGETpdSDCEYIATQGCLPATV
||. || . || ||. . ... ..| .||||. ||||||....|..||.|. | | ||||||.|. . ..|.| |.||.
ekkkaqd...qdgfahefgllpsddgi...akkvamkpenkaknrfknvvaldksrvvletk..kddpssdyinasylrddk..kkdvflaaqaPltati
NDFWRMV--WQegsLVIVMITNEVERGRNKCSRYWPSPESPEETYGLIHVTSLEEDTAnSHYILRHFLVEKRapdapeeDGGdegayESRHIFQFHFKAW
||.||.| |. .|...||.. | ..|. ||| . |.| ..| .. | |. | . | . ..| |.| . ||....|
ndlWrlvldWr...csvvvvlneldlgkdrcavywpkemgksktfGglevklrtieei.sdyvhrvldvkqv.......kkG.....etrsvkqfqlqsw
PDHGVPQDPGVVLAFMQDVNMKVQQLRS--LNPGPTVVHCSAGIGRTGTYIIIDVII-KLIEsqgwDVDIDIQKSVQIARGQRSGMVQTEQQYKFVYRAI
.| ||.. | .....| |. ..... .| .||||||.||||..| . .. |.|| . .|| ..|. | .| ||.| || ..| |.
ddmGvqkrpatlisilqlvkavservtantkastpilvhcsaGvGrtGvfislysalakvie....esrvdifgfvkklrkdrpsmvetvdqyiliyeal
LHYV-EASTQ
.. . |.
veaymsgntd
|
|||||||||
| subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 250-522 | 8.1e-59 | 194.1 | In-house | 31-277 (515) | alignment | ||
Range on Protein: 250-522
Range on HMM: 31-277/515.0
HLYSRKEGVKPENRPKNRFKNILPFDHTRVILKDgyDPDVPGSDYINANYISGetPDSDCEYIATQGCLPATVNDFWRMVWQEGSLVIVMITNEVERGRN
.| . . | .|||.|||||.| .||.|. | | |||.|| || . |.| |||.|| ..|.|.||||.|.|| |.|.|. | .
niypqtvaqeeinfkknryknilPydsvrvklev..indnPhsdyfnasyips..fdndkayiasqgPnkasvddfWrlvlqenvttiamvtklkegdki
KCSRYWPSPESPEETYGLIHVTSLEEDtANSHYILRHFLVEKrapdapeedgGDEgayeSRHIFQFHFKAWPDHGVPQDPGVVLAFMQDVNMKVQQLRsl
||..||| . .| |.| . . | . | |.. | | ||. || . ||||. |||.|||.. .| ....| . .|.
kcgkyWPdkpgdsvkfGsikvelvsle.actggikrkltvlk..........gdd....srtvtqfhfteWPdkGvpkhtssllklikevkadhgqyt..
npGPTVVHCSAGIGRTGTYIIIDVIIKLIESQGwdvDIDIQKSVQIARGQRSGMVQTEQQYKFVYRAILHYVE
| ..|||||.|||| .| || .. .. .|. . |.. | .| .|||..|| |.| |.| ..
..hpliihcsaGvGrtGvvisidsvvahakttr...mvdvfnfvtnirqkrpylvqtqeqyafiygavledll
|
|||||||||
| subfamily_PTPRN_pd | Subfamily PTPRN | 252-523 | 4.1e-58 | 191.4 | In-house | 46-294 (297) | alignment | ||
Range on Protein: 252-523
Range on HMM: 46-294/297.0
YSRKEGVKPENRPKNRFKNILPFDHTRVILKDGYDPDvpGSDYINANYISGETPDSdCEYIATQGCLPATVNDFWRMVWQEGSLVIVMITNEVERGRNKC
... . ...| ||| |..||.||.|| ||. . . |||||| | . | . |||||| |..|| |||.|||..|. |||..|. | | ..|
stkevakaeknvkknrskavlpydhsrvklkeeasae..ksdyinasaildhdpra.payiatqgplastvadfwqmvweqGvvvivnltrleeegvkqc
SRYWPspESPEETYGLIHVTSLEEDTANSHYILRHFLVEKRApdapeedggdegAYESRHIFQFHFKAWPDHGVPQDPGVVLAFMQDVNMKVQQlRSlnp
.|||| . .|.|.. | . | |..| | . . |.| . |||| .||..||| . .| | . || . ||
krywp..deGsevyhiyevhlvsehiwcddylvrsfylknlq............tsetrtvtqfhflswpeegvPasaksllefrrkvnksyrG.rs...
GPTVVHCSAGIGRTGTYIIIDVIIKLIEsQGWdVDIDIQKSVQIARGQRSGMVQTEQQYKFVYRAILHYVEA
| |||||.| ||||.||.||.... . .| .||| ... | ||.|.|.|..|..|.. |. . |.|
cpivvhcsdGaGrtGvyilidlvlnrll.kGv.keidiaatlehlrdqrpglvktkdqfefaltavaeevna
|
|||||||||
| subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 261-518 | 4.1e-58 | 191.4 | In-house | 2-236 (237) | alignment | ||
Range on Protein: 261-518
Range on HMM: 2-236/237.0
ENRPKNRFKNILPFDHTRVILKDGYDPdvpgSDYINANYISGETpDSDCEYIATQGCLPATVNDFWRMVWQEGSLVIVMITNEVERGRNKCSRYWPSPES
||. |||. || .||.||.|| ||||||.|. | . .|||.|| | .. .|||.||||| ||||.| .|. . || .|||| .
enkiknrygnivaydhsrvvlkgagsg....sdyinatylkgfd.gtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpstdq
PEeTYGLIHVtSLEEDTANSHYILRHFLVEKRAPDApeedggdegayESRHIFQFHFKAWPDHGVPQDPGVVLAFMQDVNMKVQQLRslNPGPTVVHCSA
|. .|| . | || . . | | .| .|. || | | |.|..| .|||.|||| .| | ... . . . . || ..||||
pa.aygvltv.slkkkeefsdytvrslllskrltlk...........evrlihqyqftswpdrgvpqqtaallrfrkniinrsphvs..esgpwiihcsa
GIGRTGTYIIIDVIIKLIESQgwDVdIDIQKSVQIARGQRSGMVQTEQQYKFVYRAIL
|.|||| ...|| ... . . | .|| . |. .| ..||..|| |....||
gvgrtgiflvidamlrqakek..kv.vdiynyvysieedrpyiiqtkdqyvfihqtil
|
|||||||||
| subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 227-525 | 1.4e-57 | 189.8 | In-house | 13-282 (287) | alignment | ||
Range on Protein: 227-525
Range on HMM: 13-282/287.0
NQDMYGKAGFWEEFEQMQQ-QETRHlySRKEGVKPENRPKNRFKNILPFDHTRVILKdgydpdVPGSDYINANYISGETpdSDCEYIATQGCLPATVNDF
.. |. || . | ..| ..... . .. ..|..|||...||. | ||.|| ||||| .| | .. ..|.... . |. .|
kghakgnegfknqftvleqvtqred..evthniasqnkdknRltqilvpdnyrvllk......gehpdyinavfidgyk..ekkafiiaesPmfntarnf
WRMVWQEGSLVIVMITNEVERGRNKCSRYWPSPESpeETYGLIHVTSLEEDtANSHYILRHFLVEKRAPDApeedggdegayESRHIFQFHFKAWPDHG-
|...... .|||...| | ...| .|||. .| ..| ... |.|. |..|| |.. |... .. . ... |... .|...|
WkliddrnvtaivmlcqekendeevcyqyWpeeks..vvlGeyniellnee.vnagyierklevknknkag...........dkqqvkqyqitnWdstgk
VPQDPGVVLAFmQDvNMKVQqLRSlNPGPTVVHCSAGIGRTGTYIIIDVIIKLIESQGwdvDIDIQKSVQIARGQRSGMVQTEQQYKFVYRAILHYVEAS
|.. ..| . .. .| | .. .. |||||...||..... ... |. . .| ||. . .. | |. |.||| .||||.. ..|.|...
vtepqtillvi.ee.myktq.rkr.gntsivvhCsdtvGrsamfcaaattinkckteG...viDvfqvlksqriqkpgsvqtveqykfindivleyldsf
T
.
e
|
|||||||||
| subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 239-528 | 3e-57 | 188.6 | In-house | 15-284 (287) | alignment | ||
Range on Protein: 239-528
Range on HMM: 15-284/287.0
EFEQMQQQETRHLYSRKEGVKPENRPKNRFKNILPFDHTRVILKDgyDPDVpGSDYINANYISGETPDSdcEYIATQGCLPATVNDFWRMVWQEGSLVIV
|...... . |. . . |||. ..||.|.|||.| ... |||||||||... | | ..||.|| ..|||.||||.|... | ...
evdalkedsesstatfkaaeelaavkknryadvlPiddtrvllsa..egel.Gsdyinanyvasytdde..afiaaqgPiaatvrdfwravletrsasvi
MITNEVERGRNKCSRYWPSPESPEETYgLIHVTSLEEDTANSHYILRHFLVEkrapDApeeDggdegAYESRHIFQFHFKAWPDHGVPQDPGVVLAFMQD
..| ||| .|.|| .||| .| | |. |. | . .| | . . |. . . |.| . |... .|||.... .. |. |
tmtreveearlkcykywPerevPmrvG.GysvvlldydikePeygvralrli....dl...e.....trearvvkqldllswPdkvlaPtavglirfvld
VNMKVQQLRSLN-PGPTVVHCSAGIGRTGTYIIIDVIIKLIESQGwdvDIDIQKSVQIARGQRSGMVQTEQQYKFVYRAILHYVEASTQLK
|. ... |. . || |||...||||.|... . |... |. | .|. . | | .| ..||. |....| |. | .. ||
vkqhielardasevGPlvvhddvGiGrsGillatlvlvsrledlG...rvdvaavvirlreyraalvqavvqlrllyealvtyyktnpqly
|
|||||||||
| subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 230-529 | 1.7e-56 | 186.5 | In-house | 20-288 (315) | alignment | ||
Range on Protein: 230-529
Range on HMM: 20-288/315.0
MYGKAGFWEEFEQMQQQETRHLYSRKegvKPENRPKNRFKNILPFDHTRVILKdgYDPDVPGSDYINANYISGETPDSdcEYIATQGCLPATVNDFWRMV
| || ...| . . . | | | ||. |||. ||...|..|| | |.|||.|||.| | . |||.|| ..|.|.||||.|
astkngfkqdyesipggqlhpldvak...kienkqknryiniiaydksrvqlp..llendphsdyvnanfidGynkkr..ryiaaqgpnvasvkdfwrlv
WQEGSLVIVMITNEVERGRNKCSRYWPSPespEETYGLIHVTSLEEDtANSHYILRHFlvekrapdapeedgGDEGAYESRHIFQFHFKAWPDHGVPQDP
..| |||.|| ||. ..|. .||| . .|| | || .|. |..| | . . |...|.|. .||| |||.
feedigkivmltnlvegekrkaekywpdk...kviyGkitvtrksee.vnteytvrtl..............svvfgdnirevvqlhytswpdmgvpkyt
gvvLAFMqDVNMKVQQLRSLNPGPTVVHCSAGIGRTGTYIIIDVIIKLIESqgwDVDIDIQKSVQIARGQRSGMVQTEQQYKFVYRAILH-YVEASTQLK
...| .. .|.| . . |. |||||||.|||||.| .| ... .| . ||. . .. | .| .|||. .||.|.| |.| .| | .
...iplm.nlirtvkqhhtnsvgaivvhcsaGvGrtGtfitldavldqaea...enaidvynfitgvrqnrikmvqvaeqyqfiydalletfvcgdtsia
Q
|
q
|
|||||||||
| subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 256-524 | 7.5e-56 | 184.4 | In-house | 42-287 (297) | alignment | ||
Range on Protein: 256-524
Range on HMM: 42-287/297.0
EGVKPENR---PKNRFKNILPFDHTRVILKDGydPDVPGSDYINANYISGETPdsdcEYIATQGCLPATVNDFWRMVWQEGSLVIVMITNEVERGRnKCS
.. . |.. .|.|.|||||.| ||.|. | | |||.|| .. | ..|.|| .|||.|||.||..| .|||.... || . ||
pqtvaekkvnfeksRYkniLPydssRvkLaiv..nddpdsDyvnasfvkgnkh....rlittqmPmkatvadfWamvldeqvstivmlnddnerdk.kca
RYWPspESPEETYGLIHVTSLEEdTANSHYILRHFLVEKRAPDApeedggdegayeSRHIFQFHFKAWPDHGVPQ--DPGVVLAFMQDVNMKVQQLrslN
|||. .. |.| . |. | . . .| |.. |.| .. | | . |..| |||. |.. . .| ....|. . .| .
ryWs..dkgvttfGdvsvvllsv.sereGfikrelevtkgkaka............rrvvkqyqfveWPdkaverkdsassllklisevrkdfsqn...a
PGPTVVHCSAGIGRTGTYIIIDVIIKLIESQGwdvDIDIQKSVQIARGQRSGMVQTEQQYKFVYRAILHYVEAS
|| .|||.||.|||| .. || .. .. . ..|| . |. | .| .|||..|||||| |.| .. .
egPllvhclaGvGrtgvlltidsvvaeakrek...evdifglvkklrqerpylvqtkeqykfvyvavleallse
|
|||||||||
| subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 217-521 | 1e-53 | 177.4 | In-house | 8-279 (439) | alignment | ||
Range on Protein: 217-521
Range on HMM: 8-279/439.0
KQRVSELEKQNQDMygkagFWEEFEQMQQQETRHLYSRKEGVKPENRPKNRFKNILPFDHTRVILKDgyDPDVPGSDYINANYISGETpdSDCEYIATQG
.. | .|.|..|.. | |.||... . . . ...|||.|.. .||||||.|.. | || | ||||||| | | ||||||
qehvekldknkqei.....fkeifekinstspdyaciaslaaqeydqtknrykdvgafdhtrvtlqe..ipgvphshyinanyikGyy..ddklyiatqg
CLPATVNDFWRMVWQEGSLVIVMITNEVERGRnkcsrYWPSpeSPEETYGLIHVTsLEEDTANSHYILRHFLVEKRApdapeeDGGDegayESRHIFQFH
|..||||.|... . |||.|| || . |||| . | || | | . . .|..| | | .. | .. | ..|||
pkkettddfwrlviekktvtivmltnlvesyk.....ywps..daevcygdiavr.vdrnielpnyvirgfkvfner......dtte....kertvlqfh
FKAWPDHGVPQDPGVVLAFMQDVNMKVQqlrSLNPGPTVVHCSAGIGRTGTYIIIDVIIKLIESqgwDVDIDIQKSVQIARGQRSGMVQTEQQYKFVYRA
. ||||. || . || |.. .| . . . || |||||||.||||| | .|. .. . . . .||. |.. | || |||. || |.| |
yiawpdknvpaqashvldflrainsand...keeygpvvvhcsagvGrtGtiialdialeqlkl...enkvdikgivkvlrkqrkqmvqalcqyvfiyna
ILHYV
.| .
vledi
|
|||||||||
| subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 230-523 | 2.1e-53 | 176.0 | In-house | 11-295 (301) | alignment | ||
Range on Protein: 230-523
Range on HMM: 11-295/301.0
MYGKAGFWEEFEQMQQQETRHlysRKEGVKPENRPKNRFKNILPFDHTRVILKDGYDPDVPGSDYINANYISGETpdSDCEYIATQGCLPATVNDFWRMV
.. . .| |........| .. . |.. ||.. |||||| ..|. |.||| . |. .||||.||.| . . ..||.|| . |. ||||..
akhsnkfeeqykelkegedks...ctvglseenkalnrfknitvyddnriilkpkpnldlcqreyinasyidgys..ekkkfiaaqgpmkktlvdfWrli
WQEGSLVIVMITNEVERGRNKCSRYWPSPESPEETYGLIHVTSLEEdTANSHYILRHFLVEKRAPDA---PEEDGGDEGAYESRHIFQFHFKAWPDHGVP
||| |||.||. |. ..|| .|||. | .|..| ..|| .| .. ...|.. | . | . . .|... |.. ||..||
wqekpvsivmvtnlkegtkskceqywpnseaeseefgpftvtlvne.qvyPdfvirqlnvkiqdgsnngyierkfkvksdksswdvlqlqvtdWpqdGvv
QDPGVVLAFMQDVNMKVQqlrSLNPGPTVVHCSAGIGRTGTYIIIDVIIKLIESQGWdvdIDIQKSVQIARGQRSGMVQTEQQYKFVYRAILHYVEA
..| || ..|| .. | . . || |||||....|.|.|. ... . ..| .|. . .. | .. |.|.| .|| ..| .| |..
reprtvLqviddvihrqq...kigggpvvVHCSdtVsrsGvYcsvsiglEQckaegV...VdvfqvtkavrrskpgaVtTLeqytsiydvidmylql
|
|||||||||
| subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 261-518 | 5.6e-52 | 171.3 | In-house | 6-237 (239) | alignment | ||
Range on Protein: 261-518
Range on HMM: 6-237/239.0
ENRPKNRFKNILPFDHTRVILKDGYdpDVPGSDYINANYISgETPDSDCEYIATQGCLPATVNDFWRMVWQEGSLVIVMITNEVERGRNKCSRYWPSPES
|. |||. ||. .||.||.|. . | ||||||.|. . | |||||||. .. |||||.||| ||||.| .| ..|| .||| |
vnkaknryanivtydhsrvvlekls..ndphsdyinasylr.dydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdsts
peeTYGLIHVTsLEEDTANSHYILRHFLVEKRapdapeedggdeGAYESRHIFQFHFKAWPDHGVPQDPGVVLAFMQDVNMkvQQLRslNPGPTVVHCSA
| ..|| | . . ||.| |.. . | | |...|.|| |||.|||| || . . . . | | |.||||
...kycnlrvt.lrktevfadyiirtfvmsqv............gqteeryvyqyhftvwpdkgvpqyatavlglrrkitk..dslp..garpwvihcsa
GIGRTGTYIIIDVIIKLIESQGwdvDIDIQKSVQIARGQRSGMVQTEQQYKFVYRAIL
|.||||....|| ... . | .|| . |. | .| |||| .|| |.. |.|
gvgrtgaflvidamlrqakkqk...tvdifnyvkairedrphmvqtseqyvfihlavl
|
|||||||||
| subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 260-518 | 6.1e-52 | 171.1 | In-house | 6-238 (239) | alignment | ||
Range on Protein: 260-518
Range on HMM: 6-238/239.0
PENRPKNRFKNILPFDHTRVILKDGYdpDVPGSDYINANYISgETPDSDCEYIATQGCLPATVNDFWRMVWQEGSLVIVMITNEVERGRNKCSRYWPSPE
|. |||. ||. .||.||.|. . | ||||||.|. . | |||||||. .. |||||.||| ||||.| .| ..|| .|||
rvnkaknryanivtydhsrvvlekls..ndphsdyinasylr.dydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdst
SpeeTYGLIHVTsLEEDTANSHYILRHFLVEKRapdapeedggdeGAYESRHIFQFHFKAWPDHGVPQDPGVVLAFMQDVNMkvQQLRslNPGPTVVHCS
| | ..|| | . . ||.| |.. . | | |...|.|| |||.|||| || . . . . | | |.|||
s...kycnlrvt.lrktevfadyiirtfvmsqv............gqteeryvyqyhftvwpdkgvpqyatavlglrrkitk..dslp..garpwvihcs
AGIGRTGTYIIIDVIIKLIESQGwdvDIDIQKSVQIARGQRSGMVQTEQQYKFVYRAIL
||.||||....|| ... . | .|| . |. | .| |||| .|| |.. |.|
agvgrtgaflvidamlrqakkqk...tvdifnyvkairedrphmvqtseqyvfihlavl
|
|||||||||
| 0041856 | (Phosphotyrosine protein) phosphatases II | 262-522 | 5.4e-51 | 168.1 | In-house | 1-172 (182) | alignment | ||
Range on Protein: 262-522
Range on HMM: 1-172/182.0
NRPKNRFKNILPFDHTRvilkdgydpdvpGSDYINANYISGETPDSDceYIATQGCLPATVNDFWRMVWQEGSLVIVMITnevergrnkCSRYWPspesp
|..|||...|||.||.| ..||||||.. | |... .||||| |. ||.||.||....| .||..| . .|||
nldknrysdilpydhsr............dldyInanlylgslpatr..fiatqgpllstvadflrmlkelgittivnlt.........eelywp.....
eetyglihvtsleedtanshyilrhflvekrapdapeedggdegAYESRHIFQFHFKAWPDHGVPQdPGVVLAFMQDVNMkvqqlrslNPGPTVVHCSAG
.. |...|... ||||||| . .|.|...|. ..||..||||||
............................................ellerlgiqylylpwpDhgvpd.ldelldfieevle........eggpvlVHCsaG
IGRTGTYIIIDVIIKLiesqgwdvDIDIQKSVQIARGQRSGMVQTEQQYKFVYRAILHYVE
.|||||........|| ...... |. | .|.|||.|..|| |...|.|....
vgRtgtlvaaylmkkl........gvsleeavklvrsrRpgmvitpnqyfflqlallelll
|
|||||||||
| subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 256-524 | 4.8e-50 | 165.2 | In-house | 43-347 (350) | alignment | ||
Range on Protein: 256-524
Range on HMM: 43-347/350.0
EGVkpENRPKNRFKNILPFDHTRVILK------DGYDPDVPGSDYINANYISGE----TPDSDCEYIATQGCLPATVNDFWRMVWQEGSLVIVMITNEVE
||| | |||.|||||..|.||.|| |. . . ..|||||||.. . ..| |||||. || ||.||.... . . ||...|..||
eGv..elfaknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdve
RGRNKCSRYWPSPESPEETyglIHVTSLEEDTANS-HYILRHFLVEKRAP--DAPEE--DGGDE--------GAYESRHIFQFHFKAWPDHGVPQDPGVV
...|| |||. . . | ....| |.... |. . |.| |. | .. | |. | . ..|...| |.| .. .| .
lnlekcyrYWqegsyddit...vklaskwenimgindsslysadvkkeasdndnisddndlkdnnsltaitlaasdPyvvyqlqvknWkDlslllnPesi
LAFMQ------DVNMKVQQLRSLNPGPTVVHCSAGIGRTGTYIIIDVIIK------LIE--SQGWDV---DID-IQKSVQIARGQRSGMVQTEQQYKFVY
| .. | .. . | . . | .||||||.|||||.. .| ... .. |. || | |. |.. | || |||. .|. |.|
lqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlisiivnelrkqrismvqnldqfifiY
RAILHYVEAS
|.|.| . .
eallfyfaLr
|
|||||||||
| subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 240-520 | 3e-49 | 162.4 | In-house | 12-265 (283) | alignment | ||
Range on Protein: 240-520
Range on HMM: 12-265/283.0
FEQMQQQETRHLYSRKeGVKPENRPKNRFKNILPFDHTRVILKDGYDpdvpgsDYINANYIS-GETPDSDCEYIATQGCLPATVNDFWRMVWQEGSLVIV
.|.... .| . . ||..|||...|.| | || || ||||| .| . . | .||..|. | || |||.||..| ||
revlkrlsvpdldadi.asadenkrknrnqeivpadqwrvelksesr......dyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekitaiv
MITNEVERGRNKCSRYWPSPESpeETYGLIHVTSLEEDTANShYILRHFLVEKRapdapeedggdEGAYESRHIFQFHFKAWpdhgVPQDPGVVLAFMQD
|.|. | | |||.|||. | | || || .| | || .| . .|. . | .. . . . | . ... .. .
mltklqedlrikCsqyWPkrGs..edyGeftvtlrkettsns.fiikelllrvn...........ssakstlllahyqvidW....leygeqaiinslvk
VNMKVQQLRSLNPGPTVVHCSAGIGRTGTYIIIDVIIKLIESQGWdvdIDIQKSVQIARGQRSGMVQTEQQYKFVYRAILHY
.| . . . . || |||||.|||||...| . . .| . .. .|. . |.| | || ..||| .|||.|. ..|
fnkvislqteskkgPivvhCstgiGrtavfiaasasvkdaltesv...vdvfavvkimreqrmmavqtldqyklvhelvleq
|
|||||||||
| 0051429 | (Phosphotyrosine protein) phosphatases II | 289-536 | 4.7e-49 | 162.7 | In-house | 1-240 (272) | alignment | ||
Range on Protein: 289-536
Range on HMM: 1-240/272.0
VPGSDYINANYISGEtpdsdCE------YIATQGCLPATVNDFWRMvWQEGSLVIVMITNEVERGRNKCSRYWP----------SPESPEETYGLIHVTS
.| |.||||....| . .....|.||.|..||||. ...| .||....|.||||.||.|||| . . |. .|| ..||
lplsgyiNardvggy.....grvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtl
LEEDTANShYILRHFLVEKRAPdapeedggdegAYESRHIFQFHFKAWPDHGVPQDPgvVLAFMQDVNMkvqqlrslnPGPTVVHCSAGIGRTGTYIIID
|.| . . ||||..|... . | |.|.....|. .||||||||.. .|.... .. .|| .||||||..||||.. ..
lseellld.yilrellltllls...........agearevmhlhytdwpdhgvpqea..llellellld.........ggpvlvHCsaGkdRTGtvvall
VIIkliESQGWDVDID--------IQKSVQIARGQRSGMVQTEQQYKFVYRAILHYVEASTQLKQAFSQSST
.. . .... .| ... |. | || |.||||.||.|.|.|.|..... .. . .. ..
lll...lgvsletivddYlltnlyleeaveelraqrpgavqteeqylflyeallellrsllsvraeyllaal
|
|||||||||
| subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 263-523 | 7.7e-49 | 160.9 | In-house | 57-285 (290) | alignment | ||
Range on Protein: 263-523
Range on HMM: 57-285/290.0
RPKNRFKNILPFDHTRVILKDGYDpdvpgSDYINANYISGETPdsdcEYIATQGCLPATVNDFWRMVWQEGSLVIVMITNEVERGRNKCSRYWPSPESPE
|||.|.. | |||||||||| ||. |||. | . .| ||| | .|| |.|||| ||. .|||. . .| |. ||..|.| |
fkknrykdvvcndktrvilkdGyd.....GdyvhanyvkGlka....mfiltqGalkdtvidiwrmvlqekvaaivmlceliedGkakceqyypekeGev
ETYGLIHVTSLEEDTANSHYILRHFLVEKRapdapeeDGGdegayESRHIFQFHFKAWPDHGVPQDpgvVLAFMQdvnmKVQQLRSLnPGPTVVHCSAGI
|.| | |. |||. ... |.. . | .. | | . . .. |.|||. |.. ||... .. || . .|| ||||||||
ltfGeitvlcseeddkdaniikktlsvrdk.......dsG.....kehklkhlkikswpdksvals...tlallr....tlrilrka.sGpvvvhcsaGi
GRTGTYIIIDVIIKLIEsQGWdvDIDIQKSVQIARGQRSGMVQTEQQYKFVYRAILHYVEA
|||||.. |.| .... .| ..|. . |. | | . || . || . ...|.. .
GrtGtfvaievglqill.dGk..eldlldlvralrnsrlnsvqvdiqylalveilldlGkd
|
|||||||||
| subfamily_CG7180_pd | Subfamily CG7180 | 253-522 | 3.1e-48 | 158.9 | In-house | 33-291 (296) | alignment | ||
Range on Protein: 253-522
Range on HMM: 33-291/296.0
SRKEGVKPENRPKNRFKNILPFDHTRVILKDgYDPDVpGSDYINANYISGETPDSdcEYIATQGCLPATVNDFWRMVWQEGSLVIVMITNEVERGRnKCS
. |.. ||| ||| ...|.|..||.|. | . |||||| |. . . . ||| |.. ||..|||.|..|.. .|..|.. . . ..
dCagglrkenreknrdvkvvPyDynRvvLek.ldGee.ksdYinavyvdsflkkk..eyivteapkketvdefWrlvydeeisavvvLtktfdfak.myp
RYWPSPEspEETYGLIHVTSLEEDTaNSHYILRHFLVEKRAPDAPEEDggDEGAYESRHIFQFHFKAWPD-HGVPQDPGVVLAFMQDVNMKVQQL-RSLN
||| .| || | | .||.. .. | | . |. |.. . | | . .|... |. . || .. ... |.. ... .
sywpnks..keqygeifveiveekq.yanlkirtfkltkkivalteqe..kqvkaetRivklfqlteWeledkvPlstnalielrrrvrlwrekvdedpe
PGPTVVHCSAGIGRTGTYIIIDVIIKLIESQGwdvDIDIQKSVQIARGQRSGMVQTEQQYKFVYRAILHYVE
||.||..| | .|.| |. ||. . |.| .. .|. . |. | .| ..|.. ..||..| .|..|
egPvvvvssdGasRsGvylaidanlelvekee...evdvFeavktlrrsRpqLvenveeYkyiYdvlleavl
|
|||||||||
| subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 234-520 | 3.6e-48 | 158.9 | In-house | 20-235 (392) | alignment | ||
Range on Protein: 234-520
Range on HMM: 20-235/392.0
AGFWEEFEQMQQQetrHLYSRKEGVKPENRPKNRFKNILPFDHTRVILKDgYDpDVPGSDYINANYISGetPDSDCEYIATQGCLPATVNDFWRMVWQEG
| | ||| .. . ..| .. . |. | .|||.|||||.| .||.|. | |.| |||.|| || . |.. |||.|| .|...||||||.||
alffeefhdlpgp...diypqtvaqkeinlkknryknilpydsarvklev.id.dipdsdylnasyips..fdnekayiasqgpnaaslddfwrmvfqen
SLVIVMITNEVERGrnkcsrywpspespeetyglihvtsleedtanshyilrhflvekrapdapeedggdeGAYESRHIFQFHFKAWPDHGVPQDPGVVL
|.|.|. | . | . |||| |||..||. .|
vttiamvtklkegd.........................................................kgddartvaqfhftewPdkdvpkhtssll
AFMQDVNMKVQQLRSlnpgPTVVHCSAGIGRTGTYIIIDVIIKLIESQgwdVDIDIQKSVQIARGQRSGMVQTEQQYKFVYRAILHY
|...|. . | | ..|||||.|||| | || .. . .|. . | | .| ||||..|| |.| |.|
kfikevkadfGqyth....pliihcsagvgrtgvvisidsvvahakkt...rmvdvfnfvtnirrkrpymvqtkeqyafiygavled
|
|||||||||
| subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 261-521 | 2e-45 | 150.0 | In-house | 32-295 (297) | alignment | ||
Range on Protein: 261-521
Range on HMM: 32-295/297.0
ENRPKNRFKNILPFDHTRVILKDGydpdVPGSDYINANYISGETPDSDCEYIATQGCLPATVNDFWRMVWQEGSLVIVMITNEVERGRNKCSRYWPSPES
|||...|| .| ||| |. . ....|||||.|. ..| || .|| | |||.|||..|.... ||||... | ||.|| |||| .
sslrknryrdilatddtrvkllrv....iterdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrdkcapywpsvvq
PEETYGLIHVTSLEED--TANSHYIlRHFLVEKRapdapeedggdegaYESRHIFQFHFKAWPDHGVPQDPGVVLAF-----------------MQ----
. | . | | . . .. . . | |||.. | .||||||| | . | ..
erlkagdvvveflsstsdefdrvil.telqliyr..............sesrvvrhvqflswpdhGvpsdledlvrfqaqvcscciavpmmlalvemfta
DVNMKVQQLRSLNP--GPTVVHCSAGIGRTGTYIIIDVIIKLIESQgwdVDIDIQKSVQIARGQRSGMVQTEQQYKFVYRAILHYV
| .... ||. | ...||||||.||.| . |||.. . . |.. ..| | ||. .||| .|....| |.|. .
mvflqleslraemprnayllvhcsaGvGrsGvvvlsdvilaklrkk...ripdvaailsilreqrarlvqtleqfellydavlkkl
|
|||||||||
| 0049772 | (Phosphotyrosine protein) phosphatases II | 254-522 | 2.9e-45 | 150.7 | In-house | 38-281 (314) | alignment | ||
Range on Protein: 254-522
Range on HMM: 38-281/314.0
RKEGVKPENRPKNRFKNILPFDhTRVILkDgyDPDVPGSDYINANYISGEtpdsdCEYIATQGCLPATVNDF----------WRMV--WQEGSLVIVM--
.. . ...|| |||...|||.| .|||| . .| |||||||.|..| . .||||| |. ||.|| |||| .. . .|||
ilvadlflnrdknryldilpad.nrvil.p..glpvsgsdyinasyvdgf.....lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivmsr
-------------------ITNEVERGrnkcsrywpsPESPEETYGLIHvtsleedtanshyilrhflvekrapdapeeDGGDEGAYESRHIFQFHFKAW
... ..| .| ..... |.. . ... . .|...... .
devladelsrLdaAlgKtpllildgng..........neptaadlellk..............................eelydpelferlgikylripv
PDHGVPqDPGVVLAFMQDVNMKvqqlrsLNPGPTVVHCSAGIGRTGTYIIIDVIIKLIesqgwdvDIDIQKSVQIARGQRS-----GMVQTEQQYKFVYR
||...| .. ...|.. .. ..||..|||.||.|||||..... ..|| ...... .. | .|. |.... .|| |...
pDgsap.lledfdeflefieea......dkggpvlvHCkaGkgRtgtfvvaaylmkll.......gvsleealedvrlkRpinpnpgfieqleqyefile
AILHYVE
|.|.|..
alleylk
|
|||||||||
| 0046846 | (Phosphotyrosine protein) phosphatases II | 288-521 | 7.4e-43 | 141.6 | In-house | 8-173 (176) | alignment | ||
Range on Protein: 288-521
Range on HMM: 8-173/176.0
DVPGSDYINANYISGEtpdsdcEYIATQGCLPATVNDFWRMVWQEGSLVIVMITNEVERGRNKCSRYWPSPESPEEtyglihvtsleedtanshyilrhf
. ...||||||.| | .||||| || |. ||..|....| ..|..|.||| || || .||| |...
ldldldyinanlilgs......rpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgi........................
lvekrapdapeedggdegayesrhifQFHFKAWPDHGVPQDpGVVLAFMQDVNMKVQQlrslNpGPTVVHCSAGIGRTGTYIIIDVIIKliesqgwDVDI
|... |||||||.. .| ... .. ... . ||..||||||||||||..... ... . ..
..........................qylhlpwpDhgvpdl.elllellefirealke....g.gpvlVHCsaGigRtgtlvaayllel.......ekgl
DIQKSVQIARGQRS-GMVQTEQQYKFVYRAILHYV
.... .. | ||. |.|||..||.|.|...|..
sveealalvreqRplgavqtpeQyrflyefellll
|
|||||||||
| 0036282 | (Phosphotyrosine protein) phosphatases II | 291-514 | 2.8e-42 | 139.7 | In-house | 1-163 (174) | alignment | ||
Range on Protein: 291-514
Range on HMM: 1-163/174.0
GSDYINANYISGETPDSdcEYIATQGCLPatvndFWRMVWQEGSLVIVMITNEVERGRNKCSRYWPSpespeetyglihvtsleedtanshyilrhflve
|||||||..... . ..||.||.|. ||.|....|. ..|| ..|.|.|. || .|||.
gsdyinaspldlsyitp..rliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe.................................
krapdapeedggdEGAYESRHIFQFHFKAWPDHGVPQDPGvVLAFMQDVNMKVQQlrsLNPGPTVVHCSAGIGRTGTYIIIDVIIKLIEsqgwDVDIDIQ
...|...|... ||||||| .. .| |.. |. ... . ||..||||||.||||| .... ...... .|.
.............lredlerlgiqylylpwpDhgvpdlsi.llefvkfveealse...dpggpvlVHCsaGvgRtGtlvaaylmlrgll....eslvdal
KSVQIARGQRSGMVQTEQQYKFVY
. |. .| ||.|||||..||.|.|
dlvrelRlqrpgmvqtpsQyrfly
|
|||||||||
| subfamily_ptpA1_pd | Subfamily ptpA1 | 253-478 | 2.1e-41 | 137.0 | In-house | 38-256 (418) | alignment | ||
Range on Protein: 253-478
Range on HMM: 38-256/418.0
SRKEGVKPENRPKNRFKNILPFDHTRVILKDGYDPDvpGSDYINANYISGETPDsdcEYIATQGCLPATVNDFWRMVWQEGSLVIVMITNEVERGRNKCS
|| | | |||. |||| .|||| || | . |||||||||| | | ..|.||| || |. |||||||.. .|||.. | | | ||
etsegdkkhntsknrytnilpvnhtrvqlkkiqdke..gsdyinanyidgaypk...qfictqgplpntiadfwrmvwenrcriivmlsresencrikcd
RYWPSPESPEeTYGlIHVTSLEEDTANSHYILRHFLVEKRAPDAPEEDGGDEGayESRHIFQFHFKAWPDHGVPQDPGVVLAFMQDVNMKVQQL-R-SLN
|||| | . |. | . | .. .| . . || |.| | |.... |||| .|. . ... . . .|. |
rywpeqigge.qfs.iygngnevfgtysvelveviqdpereiitrnirltfeg..etrditqyqyegwpdhnipdhtqpfrqllhsitnrqnqiipssdr
PGPTVVHCSAGIGRTGTYIIIDVIIKLI
| .||||||.|||||. ...| .
nvpiivhcsagvgrtgtfctavimmkkl
|
|||||||||
| 0043147 | (Phosphotyrosine protein) phosphatases II | 290-514 | 7.9e-41 | 135.0 | In-house | 3-154 (172) | alignment | ||
Range on Protein: 290-514
Range on HMM: 3-154/172.0
PGSDYINANYISGETpdSDCEYIATQGCLPATVNDFWRMVWQEGSLVIVMITNEvergrnkcsrywpspespeetyglihvtsleedtanshyilrhflv
.|||||||.|... ...|||||.|. |..|||||....| .||..|..
egsdyinasyldlyy..ipdrfiatqgplrntladfwrmlkelgithivnltel..............................................
ekrapdapeedgGDEGAYESRHIFQFHFKAWPDHGVPqDPGVVLAFMQDVNMKVqqlRSLNPGPTVVHCSAGIGRTGTYIIIDVIIkliesQGWdvdiDI
. ...|...|... ||||||| .. ..| |.. .. .. . ||..||||||.||||| .... .. .|. ..
............lydpellerlgiqylylpwpDhgvp.llellleflefidell...alspggpvlVHCsaGvgRtgtlvaaylml.....lgl....sl
QKSVQIARGQRSGMVQTEQQYKFVY
.. |. | .|.|.||...||.|.|
eeavalvrekRpgavqnpsqyrfly
|
|||||||||
| subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 232-529 | 1.4e-39 | 130.6 | In-house | 20-295 (305) | alignment | ||
Range on Protein: 232-529
Range on HMM: 20-295/305.0
GKAGFWEEFEQMQQQETrhLYSRKEGVKPENRPKNRFKNILPFDHTRVILKDGYdPdvpgSDYINANYISgeTPDSDCEYIATQGCLPATVNDFWRMVWQ
| ||. .|| |.. . . | . ... |||.|.. .|. || |. . | .|| |||.| || .| || | | ||| | .|
gpaglraefvamkrfnd..fekmkafkeaqeagknrykdvgcldnnrvklegpw.p....heyihanyvs..tptnpkrfictqaplektcadfwymclq
EGSLVIVMITNEVERGRNKCSRYWPSPESPEETYGLI--HVTSLEEDTANShyilrHFLVEKRAPdAPEEDGGDEGA-YESRHIFQFHFKAWPDHGVPQD
. | |. | .|.| .||. |..| . .. .. ... | ... .| . .| | ||. ..|.. ..|. ||| |||
dkveaifmlcnllekgakkcleyfaskdkdvlefeekgqkisvkfessvtl.....kfrkdakak.vtetvlviegpgekarkvthyhwidwpdrgvpaa
PGVVLAFMQDVnmkvqqlRSlNPGPTVVHCSAGIGRTGTYIIIDVIIKLIEsQGWDVDiDIQKSVQIARGQRSGMVQTEQQYKFVYRAILHYVEASTQLK
.| .... |. ||.||||||||||||. .... |.. . .| .. | .| .| | || .||..|| ||.. || |.. |.
dlailelleka.......rp.skgpivvhcsagigrtgsvvmleyildqll.agqiie.dtdkilqkireqrnnsiqtdaqylfvhqvilnyfrkkklld
Q
.
e
|
|||||||||
| 0049260 | (Phosphotyrosine protein) phosphatases II | 309-514 | 3.8e-39 | 129.1 | In-house | 9-143 (152) | alignment | ||
Range on Protein: 309-514
Range on HMM: 9-143/152.0
CEYIATQGCLPATVNDFWRMVWQEGSLVIVMITNEVERGRNKCSRYWpspespeetyglihvtsleedtanshyilrhflvekrapdapeedggdegaye
|.|||||..| |..|||||... | .|||.|...|.|. || .|.
fefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi.....................................................
srhifQFHFKAWPDHGVPQDPGVVLAFMQDVNMKvqqlRSLNPGPTVVHCSAGIGRTGTYIIIDVIIkliesqgwdVDIDIQKSVQIARGQRSGMVQTEQ
|... |||||||... ..| ... .. . . ||..||||||.|||||..... .. ...... |. | .|.|.|....
.....qylhlpwpDhgvpdlsqlllflllfiekl....aldkggpvlVHCsaGvgRtgtlvaaylml.........lgvsleeavalvrekRpgavpnpg
QYKFVY
|..|.|
qlrfly
|
|||||||||
| subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 261-521 | 1.1e-37 | 124.7 | In-house | 40-277 (307) | alignment | ||
Range on Protein: 261-521
Range on HMM: 40-277/307.0
ENRPKNRFKNILPFDHTRVILKDgydpDVPGSDYINANYISGETpdSDCEYIATQGCLPATVNDFWRMVWQEGSLVIVMITNEVERGRNKCSRYWPSPES
| |||.... |..|...| | |||| |||. . .|..|| | .|. .|| |. || ..|. . .| .. || .||| |
antdknryqdvkcqdkgrivvkf....dglasdyihanylgiai..kpkkficaqgplentqysfwamaiqekvesvimlckvielakikceqywpleeg
PEETYGLIHVTsleedtanshYILRHFLVEKRAPDAPEEDGG---DEGAYESRHIFQFHFKAWPDHGVPQDPGVVLAFMQDVNMkvqqlrslNPGPTVVH
. ..| | . . ..| ||| . . | .|| | .. .. |||.|||| . ... |. . | |||
qklvfgeapnt..........isvanlgakklapdedlinvttlkvdwaqksrtiqhlqwenwpdrgvpqinltainlleavry........dtnpvvvh
CSAGIGRTGTYIIIDVII-KLIesQGWDVdIDIQKSVQIARGQRSGMVQTEQQYKFVYRAILHYV
||||.||.|| . | .. |.| .| . |..| |. | || .||| || ...| .|.|
csaGvGrsGtivaislvqdkmi..aGinc.kdmkklveelrsqrhyaiqteaqylylhrvlleyf
|
|||||||||
| subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 259-528 | 7.5e-36 | 118.2 | In-house | 34-276 (281) | alignment | ||
Range on Protein: 259-528
Range on HMM: 34-276/281.0
KPENRPKNRFKNILPFDHTRVILKDGyDPDVPGSDYINANYISgeTPDSDCEYIATQGCLPATVNDFWRMVWQEGSLVIVMITNEVERGRNKCSRYWPSP
.| | |||. || .| .|| || |. .||| |||| .| || ||| | |||||.||| . |||. . .| |.||. |.|
qpvnnkknrylnipcldisrvqlkvk.mpnknstdyihanyir..spflkrgyiltqgpkketradfwrmiwqenttaivmlcqfletnrekcaeyfprn
ESPEETYGLIHVtSLEEDTANSHyilrhfLVEKRAPDAPEedGgdegayESRHIFQFHFKAWPDHGVPQDPGVVLAFMQDVNMkvqqlRSlnpGPTVVHC
. . | | |. | | || | . | | |.| | .. .| ||| ||. |.| .. . || | |.||
ahcclqfdklsv.syedstvnks......lvttrlnlsye..g......etrlithwlwkewpdwqvpessevmlkilrkira.....rs...tppvihc
SAGIGRTGTYIIIDVIIKLIESQGWDVDIDIQKSvQIARGQRSGMVQTEQQYKFVYRAILHYVEASTQLK
|||.||.|| . ... .. | |. || | .. |. ||| ||| .... .| . | |.
sagvgrsgtlmaveialqsihshftlpdikqivs.hlrvtgraasvqtlqqymliwkvlldfgvaykqit
|
|||||||||
| subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 262-522 | 1.6e-35 | 117.1 | In-house | 48-345 (349) | alignment | ||
Range on Protein: 262-522
Range on HMM: 48-345/349.0
NRPKNRFKNILPFDHTRVILKDGYDPDVP------------GSDYINANYISGETPDSDCEYIATQGCLPATVNDFWRMVWQEGSLVIVMITNEVERGRN
|||.|.|||..|.||.|| . . |||||||.. . . ||||| ||.||.||.... .| ... .... | . .
lfaknrykdilPyehsrvklkkslksskvikastsesdsgklddyinanylkltrisvekkyiatqaPlPstvddfykvillngvklvlsLnddkelsle
KCSRYWPSPESPEETYGLihVTSLEEDTANSHYILRHFLVEKRAPD---------APEEDGGDEGAYESRH---IFQFHFKAWPDHGVPQDPGVVLAFMQ
|| .|| . . | | | . . || . |.. ..| |..| | .... ..|. .| |.| .. .| .| ..
kcdiywqelsysnitvkl..qnsslyianvqGnslrvstvkdtdndndnnkknCdlpddddddaillavekPyellqlqvknwldlslllnPisilqale
------DVNMKVQQLRSLNPGPTVVHCSAGIGRTGTYIIIDVIIKLIE-SQGWDVDID--------IQKSVQIARGQRSGMVQTEQQYKFVYRAILHYVE
| .. . | . . . .|||||| ||||... .|... ..| | . |. |. .| . | || ||| .|. ..| |.|.|.
vkndliddlfarlyldtdqlstllvhcsaGcGrtGvlvtldlllsileplqnesnkiklqallkDlisiivnelrkqrismvqnlaqfiaiyealLkyfa
|
|||||||||
| 0044763 | (Phosphotyrosine protein) phosphatases II | 273-521 | 6.8e-34 | 112.4 | In-house | 1-171 (178) | alignment | ||
Range on Protein: 273-521
Range on HMM: 1-171/178.0
PFDHTRVILKDGydPDVPGSDYINANYISGEtpdsdcEYIATQGClpatvNDFWRMVWQEGSLVIVMITNEVERGRNKCSRYWPSPESpeetyglihvts
|.|.|||.| .....||||||..| . |...... |........| .||..|.|.|.|..|| .|||. ..
pldrtrvllsnl..eglersdyinaseilpg......lylgslpp.....addlellkelgithivnlteelelgflkcdpywpeeag............
leedtanshyilrhflvekrapdapeedggdegayesrhiFQFHFKAWPDHGVPQDPGVVLAFMQDVNMKVqqlrSLNPGPTVVHCSAGIGRTGTYIIID
.|... .||||||. . .|.|.. .. . . ..||..||||||.||.|| ....
........................................iqylhipipDhgvpdllehflefvefieeal....dekggpvlVHCsaGvgRsgtlvaay
VIIKLiesqgwdvDIDIQKSVQIARGQRSgMVQTEQQYKFVYRAILHYV
..|| ...... .. | .|. .|... |....|. |..
lmkkl........glsleeaielvrerRp.ivpnpgqlrqLyefelrll
|
|||||||||
| subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 262-526 | 1.2e-33 | 111.0 | In-house | 52-295 (310) | alignment | ||
Range on Protein: 262-526
Range on HMM: 52-295/310.0
NRPKNRFKNILPFDHTRVILKdgYDpDVPGSDYINANYISgeTPDSDCEYIATQGCLPATVNDFWRMVWQEGSLVIVMITNEVERGRNKCSRYWPSPESp
. |||. ... | .|| || | ||| |||. | .| .|| | |. |||||..|| . |... . .| || || ||||
ymhknrysdvvcldtsrvklk..id.ksryedyihanyvk..tnylrstficsqgplqhtiidfwrmifqeraesilllckvgeegrpkcvgywpslgv.
EETYGLIHVTSLEEDTANshYILRHFLVeKRAPDAPEEDGGdEGAYESRHIFQFHFKAWPDHGVPQDPGVVLafMQDVnmkVQQLRSlnpGPTVVHCSAG
|||| | || | | . . . . . | || | . . .. ||| |||.. . | . . |.| || |||||||
tetygcirvtnlsessee..feicnlav.tfvpdnvpvdeq.panlkelrvslikwpnwpdrgvpdekchtv..pqrl...laqvrh...gpcvvhcsag
IGRTGTYIIIDVIIKLIEsQGWDvdIDIQKSVQIARGQRSGMVQTEQQYKFVYRAILHYVEASTQ
..|... . ... |. .. .| .|... . . .| .||| || .. | . .. . |.
kdrlyvvvalklkidkld.rglk..vdaeevktellksraiciqtelqyliidrvriifargete
|
|||||||||
| 0051082 | (Phosphotyrosine protein) phosphatases II | 291-517 | 1.6e-32 | 107.6 | In-house | 2-149 (151) | alignment | ||
Range on Protein: 291-517
Range on HMM: 2-149/151.0
GSDYINANYISGEtpdsdceYIATQGCLPatvnDFWRMVWQEGSLVIVMITNEVERGrnKCSRYWPSPEspeetyglihvtsleedtanshyilrhflve
|||||..|. | .....| |. ||.......| .||....|.||| .| .|.|. .
lsdyinfsyvtgg.......lyrsggpla....dflellkelgiktivnlrseeerg..ycpeylpelg...............................
krapdapeedggdegayesRHIFQFHFKAWPDHGVPQDPGVVLAFMQDVNMkvqqlrsLNPGPTVVHCSAGIGRTGTYIIIDVIIklIEsqgwdvdIDIQ
........ |||.|.|. . ||.|.. .. ..||..||||||.||||| .... .. ....
...................ievlhipildwpdpglplsfdavleflellld.......kkngpvlvHCsaGkgRTGtlvalylml..lg.......vsle
KSVQIARGQRSGMVQTEQQYKFVYRAI
. .. | .| |.||..||. |...|.
ealeeyrlkrpgvvqpnqqflfqlfal
|
|||||||||
| PTPc_DSPc_SM00012 | 414-518 | 7.4e-31 | 101.8 | In-house | 4-104 (105) | alignment | |||
Range on Protein: 414-518
Range on HMM: 4-104/105.0
QFHFKAWPDHGVPQDPGVVLAFMQDVNMKVQQLRSlnPGPTVVHCSAGIGRTGTYIIIDVIIKLIESQGwdVDIDIQKSVQIARGQRSGMVQTEQQYKFV
..|...|||||||... .| ....|. . .. | .|.|||||||.|||||.. .|.... .|.. .||.. |. | ||.||||||.|| |.
hyhytgwpdhgvPeesdsilellravkknknkses..skpvvVhCsaGvgRtgtfvaldillqqleket..kevdifqivkelrkqRpgmvqteeqylfl
YRAIL
|||.|
yrall
|
|||||||||
| subfamily_CG42327_pd | Subfamily CG42327 | 237-442 | 1.1e-30 | 101.4 | In-house | 8-193 (319) | alignment | ||
Range on Protein: 237-442
Range on HMM: 8-193/319.0
WEEFEQMQqqetrHLYSRKEGVKPENRPKNRFKNILPFDHTRVILKDgyDPDVPGSDYINANYISGETpDSDCEYIATQGCLPATVNDFWRMVWQEGSLV
|||... | .| . | . ..|.|. |..|. .|||.|. .| . . |..|.|. | |... |||.| | . ||||.||. | |
aeefrdlP.....qliaradevPvtskdksrvinvvPlPetrvvlqr..igdddkdeyldasyvrGyd.dapnsyiaaqvsledsssdfwrtvweqqsrv
IVMITNEVERGRNKCSRYWPSPESPE--ETYGLIHVTsLEEDTANSHYILRHFLVEKrApdapeeD-GgdegayESRHIFQFHFkAWPDHGVPQDPGVVL
|| .|. | | ..|..|.|. |. . ..|| | || | . .. .|.. .|. . | |||.. . . |.. .|| .. ..
ivqltdlselGikvcaeylPtketldntslyGdilvt.lkgrevkdryaistlllkr.v......dke......esrelthywy.kwleaevPaeeaali
AFMQDVNMK
| . .|.
amllevrss
|
|||||||||
| subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 262-522 | 1.1e-30 | 101.4 | In-house | 55-290 (305) | alignment | ||
Range on Protein: 262-522
Range on HMM: 55-290/305.0
NRPKNRFKNILPFDHTRVILKDgydPDvpGSDYINANYISGETpDSDCEYIATQGCLPATVNDFWRMVWQEGSLVIVMITNEVERGRNKCSRYWPSPESP
. |||.... |.. | |.. | |||| |||. . .|..|| | |...|| || |. |||. . || |. ||..|||
aitknryqdvpcqdqsavkldk...ps..psdyihanyvgcpm.ipekrficaqgpldqtidefwwmviqnkveqivmlcktvelgklkcaqywpaaqge
EETyglIHVTSLEEDTANSHYILRHFLVEKRAPDAPEedGGDEgAYESRHIfqfHFKAWPDHGVPQDPGVVLAFMQDVnmkvqqlRSlNPGPTVVHCSAG
. .. . |. . |. . | .. . ||. ||. .. ||| ||| | .. . | | |||||||
kle...lksgivvenvsgskpmerdaeiqitllnlty..sgdq.kmsvrhl...qwtewpdrgvppckltslellsai.......rg.skvpivvhcsag
IGRTGTYIIIDVIIKLIES-QGWDvdiDIQKSVQIARGQRSGMVQTEQQYKFVYRAILHYVE
|||||| . |. |.. | . . . |. | ||. .|.. || |..| .| |.
igrtgtivaieyilekiaenkpcp...pmpelvkalrdqrafsiqndvqylfihrvmlnyfl
|
|||||||||
| subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 262-521 | 9.7e-30 | 98.6 | In-house | 43-271 (288) | alignment | ||
Range on Protein: 262-521
Range on HMM: 43-271/288.0
NRPKNRFKNILPFDHTRVILKDgyDPDVpgsdYINANYISgeTPDSDCEYIATQGCLPATVNDFWRMVWQEGSLVIVMITNEVERGRNKCSRYWPSPESP
| ..|..|. | ||| |.| ||| ||.|| .| . . | .| | .|.. .|.|. ... |||... .|.|..| |.||
nptrdryenlprcditrvklsd..dpdf....yiaanvvs..sakykrrlicaqaPlngtieelWkmllesdveyivmlcellekGkeksaeyfPsklGe
EETYGLIhVTSLEEDTANSHYILRHFLVEKRAPdapeedgGDEGAyesrHIFQFHFKAWPDHGVPQDpgvvlaFMQDVNMkVQQLRSLNpGPTVVHCSAG
. .| . | .. |. . ... |. . |.| . . |.. |.|.|||.. .. ... .. |.||. | |||.|||
karigrl.ctvvkkkradidklvkvsllriske.......geekv....ivkilhlleWdddgvPen......ylsplrl.levlkslq.kPivvhssaG
IGRTGTYIIIDVIIKLIESqgwDVDIDIQKSVQIARGQRSGMVQTEQQYKFVYRAILHYV
.||||| |.| .... . . | .. |.. .. | .| .|||.|| .|.| .|...
vGrtgtlililialeslrl...ddflgirsllaklreerfkaiqtemqylyvhrcvleel
|
|||||||||
| subfamily_egg_pd | Subfamily egg | 258-521 | 2.1e-28 | 93.9 | In-house | 36-270 (307) | alignment | ||
Range on Protein: 258-521
Range on HMM: 36-270/307.0
VKPENRPKNRFKNILPFDHTRVILkdGYDPDVPGSDYINANYISGEtPdSDCEYIATQGCLPATVNDFWRMVWQEGSLVIVMITNEVERgrNKCSRYWPS
.. .|. | | | . | .|| | . |.| ||...|. | |.| .| | ||.||||||.|| |||.| .| ..| |||
asdnnlekarskrvhckdssrvkl..elrrGqylddfihanrvkGk.p.llnefilaqaplkntvddfwrmvfqeevqyivmltsrkes..erceyywpk
PESPEETY--GLIHVTSLEEDTAN-SHYILRHFLVekRAPDapeedggdegaYESRHIFqfHFKaWpDhgVpQDPGVVLAFMqDVnmkVQQLRSLNpGPT
|| . | .....|. | . . . .. . .| | |.. |.. . | | . . | . | ...|| | |.
aesdslvtvpGslrienlkvdskadplfrvtklkl..vGgd...........deerfle..hwq.g.d..v.nnssdvyspl.rv...lrklrnls.kpv
VVHCSAGIGRTGTYIIIDVII-KLIesQGWDVDIDIQKSVQIARGQRSGMVQTEQQYKFVYRAILHYV
||.. |. ...| . |.. . .|. .| . ....|. | .| |.. .| |||| .| ..
vvqdilGvskaatlvaieiallsll..rGpitkslvlravvflrlrrrlsvesvllylfvyrlvlfff
|
|||||||||
| subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 295-513 | 1.5e-26 | 87.9 | In-house | 78-273 (301) | alignment | ||
Range on Protein: 295-513
Range on HMM: 78-273/301.0
INANYISgeTPDSDCEYIATQGCLPATVNDFWRMVWQEGSLVIVMITNEVERGRNKCSRYWPSPESpeetyGLIHVTSLEEDTANSHYILRHFLVeKRAP
| ||.|. |. .||||| |..| .||| |. | |||....||. .||. | |. | ... . . |...||.. .. ||.
ihanwip..tsGhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkis.....ekldigrfkikiknkelilnkkis.krtl
DApeEDGgdEGAYESRHIFQFHFKAWPDHGVPQDPGVVLAFMQDVNmkvqqlRSLNpgPTVVHCSAGIGRTGTYIIIDVIIKLIESqgwDVDIDIQKSVQ
. || | ...| . . .. |.|.|||. . .|. | .| . | ||||||||||. ..| ... . .|. | |.......
ev..eds..tgkfatrtvthyqysewtdrgvPkshaelfdlmelvk......ksek..PivvhcsaGiGrsvafigteylarevea...dptieltealk
IARGQRSGMVQTEQQYKFV
| .| |||..| ..
hlrehrwngvqtnsqlywm
|
|||||||||
| subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 263-521 | 1.8e-26 | 87.8 | In-house | 36-270 (285) | alignment | ||
Range on Protein: 263-521
Range on HMM: 36-270/285.0
RPKNRFKNILPFDHTRVILKDgYDpdvpgSDYINANYISGETPDsDCEYIATQGCLPATVNDFWRMVWQEGSLVIVMITNEVERGRNKCSRYWPSPESPE
||. .. . |||.||. .| ||| |... | . ||.||| || |..|||.|..|| ..|. .| | .||. |.|
pdlnryadvrcieetrvvlkn.hd.....rdyihaswmrmpgkd.qstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyypeklgev
ETYGLIHVTSLEE-DTANSHYILRHFLVEKrapdapEEDGGDEGAYESrHIfqfHFKAWPDHGVPQDPGVVLAFMQDVNmKVQQlrslNPGPTVVHCSAG
.| .| | . | . || . | . || | | |. . |||. |.| .. . . |. ||. . | .||||||
vkfgkyeitlteckeeaiagtilnaltvin......tedasseplymn.hv...qvpwwpdqlapedarpmielykwvk.kvnp....kekpicvhcsag
IGRTGTYIIIDV-IIKLIESQgwdvDIDIQKSVQIARGQRSGMVQTEQQYKFVYRAILHYV
.||| |.. || |...| .|.. |. | | ||. |. |.| .. |.
vgrtatfvgidyatirimenp....niemldivremramrfqavqshmqflflyvvlmeyf
|
|||||||||
| 0048076 | (Phosphotyrosine protein) phosphatases II | 372-520 | 4.5e-26 | 86.6 | In-house | 35-142 (145) | alignment | ||
Range on Protein: 372-520
Range on HMM: 35-142/145.0
SLeedtanshyilrhflvekrapdapeedgGDEGAYESRHIFQFHFKAWPDHGVPQDPGVVLAFMQDVNMKVQQlrslnPGPTVVHCSAGIGRTGTYIII
.| .| ...|...|... |||||||... .|.|.. .. ... .||..||||||.|||||....
nl............................tselellerlgiqylylpwpDhgvpdllellleflefieealke.....ggpvlVHCsaGvgRtgtlvaa
DVIIKliesqgwdVDIDIQKSVQIARGQRSGMVQTEQQYKFVYRAILHY
..... ...... .. | ||.|.|....|..|.|...|..
ylmll........lgvsleealelvrsqrpgavpnpgqlrflyefelel
|
|||||||||
| SH2 | SH2 domain | 6-81 | 6.9e-26 | 80.7 | Pfam-A | 1-77 (77) | alignment | ||
Range on Protein: 6-81
Range on HMM: 1-77/77.0
WFHPNINGAKAEEMLMERGTPGSFLTRPSQNNPGDFTLSVRREHDVTHIRIQNQGDY-YDLYGGEKFATLAELIQYY
|.| .|....||..|.|....|.|| |.|...|||.||||... .|.|.|||.. . | . ..||| .|.||...|
WyhgkisreeaerlLlegkkdGtFLvReSeskpGdytlsvvddgkvkhyriqslengkyyitenekfsslqeLvehY
|
|||||||||
| SH2 | SH2 domain | 112-187 | 7.1e-24 | 74.3 | Pfam-A | 1-77 (77) | alignment | ||
Range on Protein: 112-187
Range on HMM: 1-77/77.0
WFHGGINGREAEVLIMSKGQDGSYLVRTSAHTPGNYVLSTRVGDEISHVIIRCRDNM-FDMGGGPQFRSLSDLIEHY
|.|| |...||| |......||..||| | ..||.|.|| . ... |. |....|. . . .. .|.||..|.|||
WyhgkisreeaerlLlegkkdGtFLvReSeskpGdytlsvvddgkvkhyriqslengkyyitenekfsslqeLvehY
|
|||||||||
| 0048179 | (Phosphotyrosine protein) phosphatases II | 404-515 | 1.1e-23 | 78.9 | In-house | 41-139 (144) | alignment | ||
Range on Protein: 404-515
Range on HMM: 41-139/144.0
EGAYESRHIFQFHFKAWPDHGVPQDPGVVLAFMQDVNMKVQqlrslNPGPTVVHCSAGIGRTGTYIIIDVIIkliesqgwDVDIDIQKSVQIARGQRSGM
| ... |...|... |||||||... .|.|.. .. .. ..||..||||||.|||||........ ...... .. | .|.|.
epefleregiqylhlpwpDhgvpdllellleflefieeale.....eggpvlVHCsaGvgRtgtlvaaylmk........klglsleealalvrsrrpga
VQTEQQYKFVYR
|....|..|...
vpnpgqlrfLle
|
|||||||||
| subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 309-515 | 2.9e-22 | 73.8 | In-house | 4-197 (198) | alignment | ||
Range on Protein: 309-515
Range on HMM: 4-197/198.0
CEYIATQGCLPATVNDFWRMVWQEGSLVIVMITNEVERGRNKCSRYWPSPESPEETYGLIHVTSLEEdTANSHYILRHFLVEKRApDAPEedggdegayE
||||| | |. |||.|||. || |||. .. . |||. || || . ||. |... | . ... . . ||
rryiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttkti.ttkpdytitaliltnnt.tapp.........s
SRHIFQFHFKAWPDHGVPQDP---GVVLAfMQDVNMKVQQLRslnPGPTVVHCSAGIGRTGTYIIIDVIIKLIESQGWDVdIDIQKSVQIARGQRSGMVQ
.| | .. | .| .. |. | |.| ..| | .| . | .|||| | | || .. .|. .. | | .|. . . | | |..
treishyqftswkekttpnvalfvgfvva.srevskkyeqek...dapvivhcsdgqgftgvfvaldigvrsheesktsv.vdlfevakrlrqarcgiis
TEQQYKFVYR
. |.|.|.|.
slqhynfiyq
|
|||||||||
| subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 309-515 | 3.1e-22 | 73.7 | In-house | 5-198 (199) | alignment | ||
Range on Protein: 309-515
Range on HMM: 5-198/199.0
CEYIATQGCLPATVNDFWRMVWQEGSLVIVMITNEVERGRNKCSRYWPSPESPEETYGLIHVTSLEEdTANSHYILRHFLVEKRApDAPEedggdegayE
||||| | |. |||.|||. || |||. .. . |||. || || . ||. |... | . ... . . ||
rryiatqhplretmadfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttkti.ttkpdytitaliltnnt.tapp.........s
SRHIFQFHFKAWPDHGVPQDP---GVVLAfMQDVNMKVQQLRslnPGPTVVHCSAGIGRTGTYIIIDVIIKLIESQGWDVdIDIQKSVQIARGQRSGMVQ
.| | .. | .| .. |. | |.| ..| | .| . | .|||| | | || .. .|. .. | | .|. . . | | |..
treishyqftswkekttpnvalfvgfvva.srevskkyeqek...dapvivhcsdgqgftgvfvaldigvrsheesktsv.vdlfevakrlrqarcgiis
TEQQYKFVYR
. |.|.|.|.
slqhynfiyq
|
|||||||||
| subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 407-521 | 3.6e-22 | 73.3 | In-house | 86-194 (440) | alignment | ||
Range on Protein: 407-521
Range on HMM: 86-194/440.0
YESRHIFQFHFKAWPDHGVPQDPGVVLAFMQDVNMKVQqlRSlNPGPTVVHCSAGIGRTGTYIIIDVIIKliESQGWDvDIDIQKSVQIARGQRSGMVQT
||| . |.|...|||.|||. | || ..|||| . .. || .|||||| |||| | .| |.. |.. | .||| .. | .| ||||
iesrtlkqyhyqgwpdkgvpkfagpvlkmiqdvnesqe..ka.gngpllvhcsagagrtgviiavdsilr..eakrsd.qidifsfinsmrnnrpqmvqt
EQQYKFVYRAILHYV
.|| ||. |.|. .
peqyafvheavlegl
|
|||||||||
| subfamily_eak_pd | Subfamily eak | 248-527 | 6.1e-21 | 69.2 | In-house | 38-311 (332) | alignment | ||
Range on Protein: 248-527
Range on HMM: 38-311/332.0
TRHLYSRKEGVKPENRPKNrFKNILPFDHTRVILKDGYDpdvPGSDYINANYIsgETPDSDCEYIATQGCLPATVNDFWRMVWQEGSLVIVMITNEVERG
..| | .|. . |. .| .|.|.|. | | |||| . | .. .|| | | ||.|| .. | ||.. ..|| .
yqrllsisetarleavnrn.vvkivpydrylvrltssql...nrlGyinasla..efsevGrkyiltGiasedkvfafwqmvleqkspaivqlledvelk
RNKCSRYWPSPESPEETYGLIHVTSLEEdTANSHYILRHFLVEKRAPDAPEEDGGDEGAYESRHIFQFHFKAWpdHGVPQDPGVV-LAFMQDVNMKVQQL
.| .|.| | .| ..|. | .. . | . ..| | | | | . | .. ||. |. |.. ..
leksdkyfpdktreelkfGildverkef.vkrniletrllelskGnethrvlhykvfGwtettlpkyedflal..rkvmkevGvlllivmksallsstlk
RSLNPGPT---VVHCSAGIGRTGTYIIIDVIIKLIESQGWDVdIDIQKSVQIARGQRSGMVQTEQQYKFVYRAILHYVEASTQL
. |. .. .. | |.|....||..|.||... .. ... . . .| | ...|. |.| ..|.|. .
kyihtppsfapiiqsarGsaraGvfvvidllirlidnkkknl.ysvedlilkvkskrihsvlvalqhsfiyeivldyllrrnnr
|
|||||||||
| subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 303-533 | 2.8e-17 | 57.6 | In-house | 39-233 (255) | alignment | ||
Range on Protein: 303-533
Range on HMM: 39-233/255.0
EtpdsdceyiatqgclpaTVNDFWRMVWQEGSLVIVMITNEVERGRNKCSRYWPSPESPEETYGLIHVTSLEedtANSHYILRHFLVEKRApdapeedgG
||. |.... | .. |.||... | |..|||.|.| . . ||. . . .. .|| . |
l.................tvdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdeklkladvnvtttk...ssadvvlrtleitstl........g
DegAYESRHIFQFHFKAWPDHGVPQDPGVVLAFMQDVNmkvqQLRSLnpgptVVHCSAGIGRTGTYIIIDVIIK-LIES--QGWDVDIDIQKSVQIARGQ
. . . . ...| |... |... .| .. | . .|. |||||.||||. ........ . .| | . |..| . .. | .
e..kkkthtvkhysykGWieknaPelareilnilkvvr....dsksv.....vvhCstGiGrsaafvlaelvyqkmirsldttetveldylslleelrsk
RSGMVQTEQQYKFVYRAILHYVEASTQLKQAFSQ
|.. ..| | | .| .| ..|......
rkraihtPlqlafsilmvldlvfpkgeleakyqe
|
|||||||||
| subfamily_CG42327_pd | Subfamily CG42327 | 451-521 | 7.9e-16 | 52.6 | In-house | 247-315 (319) | alignment | ||
Range on Protein: 451-521
Range on HMM: 247-315/319.0
PGPTVVHCSAGIGRTGTYIIIDVIIKLIESQGWDVDidIQKSVQIARGQRSGMVQTEQQYKFVYRAILHYV
|| ||||| |.||||. | |. |. .| || | . |. | .|. |.| .||.|.|. . |
qGPlvvhcsdGvGrtGlviasdiairsleeskrsvd..iPqlvssvrrdrasavltkeqyefiykvlseya
|
|||||||||
| subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 265-537 | 8.4e-16 | 52.9 | In-house | 22-272 (290) | alignment | ||
Range on Protein: 265-537
Range on HMM: 22-272/290.0
KNRFKNILpFDHTRVILKdGYDPDVpGSDYINANYISgeTPdSDCEYIATQGCL-------PATVNDFWRMVWQEGSLVIVMITNEVERGRN----KCSR
..| .. | . .|||.|| || .||| ||... | .. . |.|| . .|...|| |. || . .||. . |. .| |..
dqRlevpL.veatrvvLk.gygkrf.nddyiHAnrvt..cp.nglrliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCak
YWPSPESPEETYGLIHVTSlEEDTANSHYILRHFLVEKrapdapeedgGDEGAYESRHIfqfHFKAWPDHGVPQDPGVVLAFMQDVNMKVqqlrslnpGP
| | . | ... . | . .. . |. .|. .|| . | .| | . |..|. ..|. .| |. . |
YvpesvgeelkfkgltvkC.kskekeddvetRelvvkf..........ddeeeftvtHs...llkgWnklnvqedtktllsliqkvkask........tp
TVVHCSAGIGRTGTYIIIDVIIKLIE-SQGwdvDIDIQKSVQIARGQRSGMVQTEQQYKFVYRAILhyVEAsTQLKQAFSQSSTG
.||| || | . |.. .| ..| .. ... .. | || ........ || .|. . | .. ...|....|
vivHcvdGiSrsAalaaiilgyQkiaetsg...svkledvlkalrkqralaitsalelafvdagiv..lla.ievldqfaeeete
|
|||||||||
| subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 320-514 | 9.7e-16 | 52.1 | In-house | 102-281 (302) | alignment | ||
Range on Protein: 320-514
Range on HMM: 102-281/302.0
ATVNDFWRMVWQEGSLVIVMITNEVERGRNKCSRYWPSPESPEETYGLIHVTSLEEDTAnshyiLRHFLVEKRAPDAPEEDGGDEG-AYESRHIFQFHFK
|.. .| .. | ..| ... || . .||. |. | ..| |.... .| | .| | . | .. . . ..|
stlekhwalieqynvaivvqlcsfvedeekkcaeyysdkvggelkfgrytvktvsvktd.....leeftdkksfklytveiknekkkkkvkktvdilafs
AWPDHGVPQDPGVVLAFMQDVNMKVQQlrslnpgpTVVHCSAGIGRTGTYIIIDVIIKLIESQGWDvdiDIQKSVQIARGQRSGMVQTEQQYKFVY
|||||| |... | .. . .. .||||||.||||| . | |.| . |. . |. | | | ||.||| ..
awpdhGapkeaytaldilkfcesykkn........vlvhcsaGvGrtGtlvaikyGiqlcskkkvt...dllsivlpvrqcryGavqdeqqliyll
|
|||||||||
| subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 236-375 | 3.1e-15 | 50.9 | In-house | 8-136 (267) | alignment | ||
Range on Protein: 236-375
Range on HMM: 8-136/267.0
FWEEFEQMQQQETRHLYsRKEGVKPENRPKNRFKNILPFDHTRVILKDGYDPdvpgsdYINANYISGETpdSDCEYIATQGCLPATVNDFWRMVWQEGSL
. .|||.... . . . .|. .||. . ||.|.|||||.. . |||| |. | .|.||. | |. ||. .. ...
iekefelikkisdtsst.isqsiaeknqernrlddnlpyddtrvilrtkeee......yinasyvegyk..tknafivtqdplkntitdfltvihdqkvp
VIVMITNEverGRNKCSRYWPSPESPEETYGLIHVT-SLEE
|||..|. . .. ..|| . | . | |||.
vivlltkv...ftdnirlfwPPkmgqakkyqdltvehslek
|
|||||||||
| subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 444-524 | 1.6e-13 | 45.3 | In-house | 186-262 (267) | alignment | ||
Range on Protein: 444-524
Range on HMM: 186-262/267.0
QQLRSLNPgPTVVHCSAGIGRTGTYIIIDVIIKLIESQGwdvDIDIQKSVQIARGQRSGMVQTEQQYKFVYRAILHYVEAS
.|| |. | ||.||.|.||.||...|| .. . .| || . .. .| || |.|.| ..| .... . .| |
nqlengnr.PlvvacsdGvGrsGtflvidsqlerakteg...vsdifdflrkirsqriglvdtkeryiyihellaeyaegr
|
|||||||||
| subfamily_hpo-7_pd | Subfamily hpo-7 | 313-523 | 2.8e-13 | 44.4 | In-house | 38-229 (263) | alignment | ||
Range on Protein: 313-523
Range on HMM: 38-229/263.0
ATQGCLPATVNDFWRMVWQEGSLVIVMITNEVERGRNKCSRYWPSPESPEETYGLIHVTSLEEDTanshyilrHFLveKRAPDAPEE------------D
... | |.. |.... | .. |.||... | |..|||.|.| . . |.. . | ... . .
nlysllvqtidkfyqtivqtktevvvmLcDfneegvekcssyfPlekdekqklanvnvcttkvqs........dvl..lktlellstlgeKkkthtvkhy
ggdegayesrhifqfHFKAWPDHGVPQDPGVVLAFMQdVNmkvQQLRSLnpgptVVHCSAGIGRTGTYIIIDVIIK-LIES--QGWDVDIDIQKSVQIAR
.| |... |... .| .. |. ....|| |||||.||||. . ..... . .| | . |..| . .. |
...............sykgWiekndpelareilnilk.va...rnsksl.....vvhcstGiGrsaafsvaElvyqkmirsldttstveldylsLleelr
GQRSGMVQTEQQYKFVYRAILHYVEA
.|.. ..| | | .| .|
ssrkraihtPmqLafsilmvLdfvln
|
|||||||||
| subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 412-529 | 1.3e-12 | 42.0 | In-house | 178-284 (312) | alignment | ||
Range on Protein: 412-529
Range on HMM: 178-284/312.0
IFQFHFKAWPDHGVPQDPGVVLAFMQDVNMKVQqlrslnpgPTVVHCSAGIGRTGTYIIIDVIIKLIESqgwDVDIDIQKSVQIARGQRSGMVQTEQQYK
. .. . .|||||.|. | .. |. . | . |||||.||||| ..|. .| . ....| . | .|. |.. ||
lnhyqwaswpdhgmpdscdtalrllsavkkdkk........pviahcsagvgrtgtlaliesmiaalrh...prkqnvkdsfvllrkdrarsvrvfpqyv
FVYRAILHYVEASTQLKQ
.. |..|... . . |.
yalrcvleflyskglykr
|
|||||||||
| 0038934 | (Phosphotyrosine protein) phosphatases II | 414-517 | 1.9e-11 | 39.4 | In-house | 81-173 (194) | alignment | ||
Range on Protein: 414-517
Range on HMM: 81-173/194.0
QFHFKAWPDHGVPQDPGVVLAFMQDVNMKVQQlrsLNPGPTVVHCSAGIGRTGTYIIidviIKLIESQGWdvdiDIQKSVQIARGQRSGMVQTEQQYKFV
... .||.|.. . ..| |.. |. .... ..| .||| ||.||||| .. ||...|. . ...... | | |.... .... .
eylklpfpddgtvPsleillrfldlvdeflne...dpggvvaVHCkaGlgRtGtlva....aYLiyrlgm....saeeAialfrekRpgaipnqdyleal
YRAI
..
lkry
|
|||||||||
| subfamily_Sponge-PTP-7_pd | Subfamily Sponge-PTP-7 | 455-518 | 3.5e-11 | 37.3 | In-house | 2-62 (69) | alignment | ||
Range on Protein: 455-518
Range on HMM: 2-62/69.0
VVHCSAGIGRTGTYIIIDVIIKLIESQGWdvdIDIQKSVQIARGQRSGMVQTEQQYKFVYRAIL
|||||.| |||||.| | | . | |. .|| || | | || |..| |.. |.
vvhcssgtgrtgtfiaimvemariksekl...vdifnnvqymrkcrpmmvmneieyifihdalv
|
|||||||||
| subfamily_Sponge-PTP7_pd | Subfamily Sponge-PTP7 | 455-518 | 4e-11 | 37.1 | In-house | 1-61 (69) | alignment | ||
Range on Protein: 455-518
Range on HMM: 1-61/69.0
VVHCSAGIGRTGTYIIIDVIIKLIESQGWdvdIDIQKSVQIARGQRSGMVQTEQQYKFVYRAIL
|||||.| |||||.| | | . | |. .|| || | | || | .| |.. |.
vvhcssGtGrtGtfiaimvemariksekl...vdifnnvqymrkcrpmmvmneneymfihdalv
|
|||||||||
| subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 263-340 | 1.8e-10 | 34.9 | In-house | 38-116 (347) | alignment | ||
Range on Protein: 263-340
Range on HMM: 38-116/347.0
RPKNRFKNILPFDHTRVILKD---GYDPDVPGSDYINANYISGEtpDSDCEYIATQGCLPATVNDFWRMVWQEGSLVIVMI
||| |. | |||.| . . |||| .| . ... ||| || || || |||.|| .| |
lsknrskdvklidatrvvlspeksknsraddvetyinashikfd..naskeyiltqyplpdtvrdfwkmvsvtkvtqvvti
|
|||||||||
| subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 416-525 | 2.3e-10 | 34.4 | In-house | 187-289 (302) | alignment | ||
Range on Protein: 416-525
Range on HMM: 187-289/302.0
HFKAWPDHGVPQDPGVVLAFMQDVnmkvQQLRSLNPGPTVVHCSAGIGRTGTYIIIDVIIKLIESQgwdVDIDIQKSVQIARGQRSGMVQTEQQYKFVYR
... |... ||. . . . ...| .. . .||. |.|| |. . | .. .... . |. |. | ||. .|.. .|| ..|.
vltnWkqkkvpvkyaeliktaakv....fakkikadentvivSknGaGRagafltlavaveklqkg...kepnikeivksiRsqRpravdslkQyvslyi
AILHYVEAST
|.| |.
alllyikkkv
|
|||||||||
| subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 239-303 | 1.5e-09 | 31.8 | In-house | 18-77 (244) | alignment | ||
Range on Protein: 239-303
Range on HMM: 18-77/244.0
EFEQMQqQETRHLYsRKEGVKPENRPKNRFKNILPFDHTRVILKDGydpDVPGSDYINANYISGE
|| . . ||.. . . | | |||. ||||||.||||| |||||||||| |
efvgls.dhtrefl.qtnavlsanatknryinilpfdetrvilsss...kkegsdyinanyiqgs
|
|||||||||
| subfamily_Sponge-PTP3_pd | Subfamily Sponge-PTP3 | 257-316 | 3.2e-09 | 30.8 | In-house | 43-95 (95) | alignment | ||
Range on Protein: 257-316
Range on HMM: 43-95/95.0
GVKPENRPKNRFKNILPFDHTRVILKDGYDpdvpgSDYINANYISGETPdSDCeYIATQG
| | ||||| ||.|.| |||.| | |||||| .. | . .| |||.||
gsseanipknrflnifpydatrvvlttkrd.....sdyinacfvdgyar.knc.yiaaqg
|
|||||||||
| subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 259-302 | 1.3e-08 | 28.6 | In-house | 44-85 (440) | alignment | ||
Range on Protein: 259-302
Range on HMM: 44-85/440.0
KPENRPKNRFKNILPFDHTRVILKDGYdpDVPGSDYINANYISG
|.|. |||..||| .||.||.|.. || |||||| ||.|
lpnnkvknryrnilaydhsrvmleevk..gvpdsdyinasying
|
|||||||||
| subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 405-528 | 1.3e-08 | 28.8 | In-house | 167-286 (303) | alignment | ||
Range on Protein: 405-528
Range on HMM: 167-286/303.0
GAYESrHIFQFHFKAWPDHGVPQDPGVvlAFMQDVNMKVQQLRSLNPG-PTVVHCSAGIGRTGTYIIIDVIIKLIESQgwDVDIDIQKSVQIARGQRSGM
| | | . |.|||| .| | |.... || .. ||| .| ||.||. ... . |. . .|. | .. | |
gdyks.flhvhhykawphnsipsdgsp..kfvkqiwqlqsvlrkysdstptvymslsgcgragtfalfetahlslhse..qasldlvkclenvrngrlha
VQTEQQYKFVYRAILHYVEASTQLK
|| |. .|| . .| |
vqnlsqfsvvytllaehvldngick
|
|||||||||
| subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 255-341 | 2.1e-08 | 28.2 | In-house | 42-116 (303) | alignment | ||
Range on Protein: 255-341
Range on HMM: 42-116/303.0
KEGVKpeNRPKNRFKNILPFDHTRVILKDgydpdvpgSDYINANYISGetpDSDCEYIATQGCLPATVNDFWRMVWQEGSL-VIVMIT
.. || | |||| ... .||..| | | | || |.|. ||. | || |. | |||.|. .. |....|
nqfvk..nmdknrfvdvicldhskvklsd........ssyihasylel...dsskkailtqlplshtaadfwqmiieqkvkcvllllt
|
|||||||||
| subfamily_PTPDC1_pd | Subfamily PTPDC1 | 407-515 | 3.3e-08 | 28.2 | In-house | 78-170 (182) | alignment | ||
Range on Protein: 407-515
Range on HMM: 78-170/182.0
YESRHIFQFHFkAWPDHGVPQdpgvvLAFMQDVnMKVQQlRSLNPGPTVVHCSAGIGRTGTYIIIDVIikliesqgWDVDIDIQKSVQIARGQRSGMVQT
. ..|. . | .|.|.||. | . |. .|| . .|. | . ||| || |||| | .. . ... .|.... | .|. .||
lmeqgiyvynf.gwkDygvas.....leriLdi.vkvva.falqegkvavhChaGlGrtGvliacylv........yakrltaekaiklvrskrpksiqt
EQQYKFVYR
.| ..|
reqvelvke
|
|||||||||
| subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 266-354 | 4e-08 | 27.3 | In-house | 47-127 (312) | alignment | ||
Range on Protein: 266-354
Range on HMM: 47-127/312.0
NRFKNILPFDHTRVILKDgyDPdvpgSDYINANYISGETPDSdcEYIATQGCLPATVNDFWRMVWQEGSLVIVMITNEVERGRNKCSRY
||. || .| | | | || ||.. | ...||| | |. ||... || |.... || | .||..|
nrypniqcwdrgrftlag..de....nfyihanfvkictkpe..rfvctqgplentcthfwqlalslgstsiillcgfvedgsekcaky
|
|||||||||
| PTEN_1 | 399-498 | 6.3e-08 | 27.6 | In-house | 82-172 (196) | alignment | |||
Range on Protein: 399-498
Range on HMM: 82-172/196.0
EDGGDEGAYESRHIFQFHFKaWPDHGVPQdpgvvLAFMQDVNMKVQQLRSLNP--GPTVVHCSAGIGRTGTYIIidviIKLIESQGWDVDiDIQKSVQIA
. .|. .. ... . || ..|||.| |....|. .. . ....| . .||| ||.||.|| .. |........| . . |...
grsydleeffksgveylhfp.ieDhgaps.....lselfdicksfiewllsdpngnvVlVHCkaGlgRsGtvva....ayLmykgkltad.eAlelvrek
RG
|
Rp
|
|||||||||
| subfamily_Sponge-PTP-4_pd | Subfamily Sponge-PTP-4 | 289-376 | 2.5e-07 | 25.1 | In-house | 10-90 (130) | alignment | ||
Range on Protein: 289-376
Range on HMM: 10-90/130.0
VPGSDYINANYISgeTPDSDCEYIATQGCLPATVNDFWRMVWQEGSLVIVmITNEVERGrnkcSRYWPSPESPEETYGLIHVTSLEED
..| .||||... . ||. || | .| |||.|. . |.| . || ||| | | | ||. . |
lqgntyinasfvG..llgrtaeylltqhpladtsmdfwkmmleryvnvlv.vlgsveee....deywpdsePlewyeediivtltdrd
|
|||||||||
| subfamily_Sponge-PTP-2_pd | Subfamily Sponge-PTP-2 | 262-432 | 8.3e-07 | 22.1 | In-house | 27-161 (169) | alignment | ||
Range on Protein: 262-432
Range on HMM: 27-161/169.0
NRPKNRFKNILPFDHTRVILKDGYDpDVpGSDYINAnyisgetpdsdceyiatqgclpatvndfwRMVWQEGSLVIVMITNEVERgrnkcSRYWPSpesp
| ||| | |||| |. . |. ||||||| ||.|. . |||.. . .. .||
netknrpagplapshtrvklqrvme.dl.gsdyina.............................rmiwetnasvivvlgdtddk.....nnfwpe....
EETYGLIHVTSLEEDTANSHYILRHFLVEK-RAPDAPEEDGGDEGAYES---RHIFQFHFKAWPDHGVPQDPGVV
| | | | | ..| |. . . . .. | |.. .. .|. .||. |||| | |
kedyqlhpavilgewytdslyvrtdkvhantsgveglfevsmvihsydddvteklsllhystwpqngvpqspvhv
|
|||||||||
| subfamily_Sponge-PTP2_pd | Subfamily Sponge-PTP2 | 262-432 | 1.1e-06 | 21.6 | In-house | 26-160 (169) | alignment | ||
Range on Protein: 262-432
Range on HMM: 26-160/169.0
NRPKNRFKNILPFDHTRVILKDGYDpDVpGSDYINAnyisgetpdsdceyiatqgclpatvndfwRMVWQEGSLVIVMITNEVERgrnkcSRYWPSpesp
| ||| | |||| |. . |. ||||||| ||.|. . |||.. . .. .||
netknrpagplapshtrvklqrvme.dl.gsdyina.............................rmiwetnasvivvlGdtddk.....nnfwpe....
EETYGLIHVTSLEEDTANSHYILRhflvEKRAPDAPEEDGGD-----EGAYES---RHIFQFHFKAWPDHGVPQDPGVV
| | | | | ..| |. .| |.. .| . |.. ... .|. .||. |||| | |
kedyqlhpavilGewytdslyvrt....dkvhpntsgveglfevslvihsydddvteqlsllhystwpqngvpqspvhv
|
|||||||||
| Peptidase_M4_C | Thermolysin metallopeptidase, alpha-helical domain | 453-549 | 1.9e-06 | 14.1 | Pfam-A | 79-148 (164) | alignment | ||
Range on Protein: 453-549
Range on HMM: 79-148/164.0
PTVVHCSAGIGRTGTYIIIDViikliesqgwdvdidiqksvqiaRGQRSGMVQTEQQYKFVYRAILHYVEASTqlkqAFSQSSTGTVQTTESLYGNA
. ||...|| |.... ... ...|. .| .||| .|..... |.. ....| ...|||.
nggvHlnSGilNkafyllaeg.......................sevkvtgigiekaekifyraltkyltsts....dFaearaaviqaAkdlygak
|
|||||||||
| subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 406-524 | 2.8e-06 | 21.1 | In-house | 223-341 (347) | alignment | ||
Range on Protein: 406-524
Range on HMM: 223-341/347.0
AYESRHIFQFHFKAWPDHGVPQDPGVVLAFMQDVNMKVQQL--RSL-NPGPTVVHCSAGIGRTGTYIIIDVIIK-LIESQGWDVDIDIQKsvqiARGQRS
|. . .|| . |.| |||... . . .| . | || | |. |. | .. .||. ... . |.| ..| | ||.
cseatfakvyncttwpwkkypddekkvlalvrapvkesstslianleklapvvvmcdlgldrsatvvltsiiieqvldgktpdcddlfkk....mrdqra
GMVQTEQQYKFVYRAILHYVEAS
|. | . || | |.
gvftmsifytyairaalfylklk
|
|||||||||
| subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 310-357 | 7.4e-06 | 19.5 | In-house | 237-281 (440) | alignment | ||
Range on Protein: 310-357
Range on HMM: 237-281/440.0
EYIATQGCLPATVNDFWRMVWQEGSLVIVMItNEVErgRNKCSRYWPS
.|||| | .|| ||||.| . |.|. |... . || |||
afiatqmpldstvldfwrlvhdyristiiml.nqln..dktcsiywpv
|
|||||||||