Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
subfamily_PTPRD_pd | Subfamily PTPRD | 78-436 | 4.7e-137 | 453.0 | In-house | 2-359 (564) | alignment | ||
Range on Protein: 78-436
Range on HMM: 2-359/564.0
HPPLNVSDFIEMMALLQSNNSDRLEEEYPDIELEWNFTSYAAKLPINHGKNRYVNIIPYDHSRVTLK-PDGNPGSDYINASFIGGLNSPKDYIATQGPIP
..|..|... | .| |..|.. ..|||| .|| . .|| ||. |.| |||| ||..|||||| |. .|..|||||||||| | ...| |||||||..
skpipvaelkehvaklkansdlkfeeeykkieegqqftweaankpaNkaKNRyanivaYdhsRVvLskvegdegsDYINAsfidgyrkrkayIAtqgPla
AAFPDFWRMIWEYNVPTIIMVTNLKEDDKIKCHQYWPSFGAANYGSFQVTLKEVETVADYAIRTFQLqSLHGQGPIKEVRQYHFLVWPDHGVPQYATPLL
.. |||||.||.|. ||.|.|.|.| .| |||.|||. | ..||...|||.| |..||| ||||.| . . . .||||.|| |||||||..||.||
etiedFWRmvweqnsstiVmltkleEkgkvkchkYWPekgtetygeltVtleeeeeladyeirtfkl.kkkkssesreVrqFhFtsWPdhgvpesatslL
SFQKRVRNHHKGKPGPMVVHCSAGVGRTGTFITIDTMIMKIDAEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAIMCRDTTIPAVHMATKIATL
.. ..||.... . ||.|||||||||||||||.|| |. .| .|. |||...|. .| ||.|||| .|| |.|.|||||. | .| ... .. ... |
dlirkvralnepdagPivVhCSaGVGRTGtfividamlerikeektvDiyqyvkalrkqRnamVqteeQYiFiheailealacgntevesenlkqhlqkL
KEIAPSSGKTGFQSQFETLESSSPTDdDFDCSIAQLSDNLAKSRVKEHLPPNDYRVVLST
.|. . .. ||.. |. |....... . . |. . |. | | . |. . |||||.
aeveedtemtgleleFqrLatakeie.leefavatkpknkkknrfsnilalescrvvlsa
|
|||||||||
subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 82-395 | 3.5e-109 | 359.7 | In-house | 3-318 (318) | alignment | ||
Range on Protein: 82-395
Range on HMM: 3-318/318.0
NVSDFIEMMALLQSNNSDRLEEEYPDI-ELEWNFTSYAAKLPINHGKNRYVNIIPYDHSRVTLKP-DGNPGSDYINASFIGGLNSPKDYIATQGPIPAAF
.|.|. . .. |... . |.||| . | ..||. . |.|. ||||.||..|||.|| |.. .|..|||||||..| | .. | |||.|.|.| ..
svedleshvrrlresGelllseeyerlsrseetvtslkslepvnkaknryanilaydhtrvkLqmlegeegsDyinanyidGyrrkkayiaaqaPlpeti
PDFWRMIWEYNVPTIIMVTNLKEDDKIKCHQYWPSFGAANYGSFQVTLKEVETVADYAIRTFQLQSlHGQGPIKEVRQYHFLVWPDHGVPQYATPLLSFQ
.|||||.|| | .|.|.|...| |.|.|.|||| |. .||. .|.||| ...|| .|.|... ... ..|||||. |||.|||. .. ||..
eDfWrmvWeqnsavivmltqeeergkakvhryWPskgsrsygklvvelkeevelsdyvlrefkvtr.teeeesrqvrqyhytsWpdegvpesgaslldlv
KRVRNHH-KGKPGPMVVHCSAGVGRTGTFITIDTMIMKIDAEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAIMCRDTTIPAVHMATKIATLKE
..|.. . | . ||.||||||||||||.||..|... .| ||..||.|..|. .| || |||| .||.|.....|||... || . | .....| |.|
rqvskaqqksgagpivvhCsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqtedqyefiydvllealasgdtevdasdlrsrirelre
IAPSSGKTGFQSQFETL
| ||.| .. .|. |
qdpesgttemdaefqrl
|
|||||||||
subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 80-392 | 4.3e-103 | 339.7 | In-house | 4-318 (319) | alignment | ||
Range on Protein: 80-392
Range on HMM: 4-318/319.0
PLNVSDFIEMMALLQSNNSDRLEEEYPDIELEWNFTSYAAKLPINHGKNRYVNIIPYDHSRVTLKP-DGNPGSDYINASFIGGLNSPKDYIATQGPIPAA
...| .. | . |.|. . ||.|. ... |.| . |. ..|. |||| ||..||..||.|.. || .|||||||||| | . . .||||.|. .
eievqeLkerlkalastgetllekefkllkeavndtfdsaskeenkkknryqnilaydrtrvvlseldgvegsdyinasfidgyqerekfiatqaPlent
FPDFWRMIWEYNVPTIIMVTNLKEDDKIKCHQYWPSFGAANYGSFQVTLKEVETVADYAIRTFQLQSLHGQGPIKEVRQYHFLVWPDHGVPQYATPLLSF
. |||||.||... ...|.|.|.| |.|...|||. .|| . |||.| | .|| || ..|. . .. .|| ..... ||||.||..|| || .
iedfWrmvWeeessivvmltklveklkvklkkywpeenfeeyGrlivtleeeeeledyiirklklnkkssevetRevkhfqyteWpdhdvPekatslldl
QKRVRNHHKG-KPGPMVVHCSAGVGRTGTFITIDTMIMKIDAEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAIMCRDTTIPAVHMATKIATLK
||.|. ... . ||.|||||||||||||||..| |. .. ||..|.|..|. .| || |||. .|| |...|.|||. . || | .. ... .|.
lkrirksrektqsgPivvhCsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyealleaveagdteievqdlrdrlkqla
EIAPSSGKTGFQSQF
| . .|.||.. .|
ekvadtgetgleref
|
|||||||||
0051299 | (Phosphotyrosine protein) phosphatases II | 78-357 | 8.5e-101 | 332.4 | In-house | 2-286 (288) | alignment | ||
Range on Protein: 78-357
Range on HMM: 2-286/288.0
HPPLNVSDFIEMMALLQSNNSDRLEEEYPDIELEW-NFTSYAAKLPINHGKNRYVNIIPYDHSRVTLKPDGN-PGSDYINASFIGGLNSPKDYIATQGPI
. ...|....... |. |. .|.||. .. . ..| .||.|| |. ||||..|.||||||| |.. .. .||||||||.| | |... .||||||
dteisveellklvlkllangltglleefeellsllpdltlsaallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyidgynlkrkfIatqgPl
PAAFPDFWRMIWEYNVPTIIMVTNLKEDDKIKCHQYWPSFGAANYGSFQVTLKEVETVADYAIRTFQLQSLH---GQGPIKEVRQYHFLVWPDHGVPQYA
| . |||||.||.||..|.|.|.| |....||.||||. | .|| ..|||...|. .|| .||.... |. |.| ..|...|.. |||||||...
pntvedFWrmvweqnvrvIvmltklvelgrekcaqYwplggsltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdsp
TPLLSFQKRVRNHHKGKPGPMVVHCSAGVGRTGTFITIDTMIMKIDAEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAI
..||.| ..||.... ..||.|||||||||||||||..|.... ...|| ||....|. .| .|..|||| .|| |...|.||..
ellldflrlvrkalasgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyealleyl
|
|||||||||
0050432 | (Phosphotyrosine protein) phosphatases II | 75-362 | 5e-100 | 330.1 | In-house | 20-304 (308) | alignment | ||
Range on Protein: 75-362
Range on HMM: 20-304/308.0
DPNHPPLNVSDFIEMMalLQSNNSDRLEEEYPDIELEWN-FTSYAAKLPINHGKNRYVNIIPYDHSRVTLkpdgNPGSDYINASFIGGL--NSPKDYIAT
... .|.| |..... . ... .||||. .. . .. ..|.|| |. ||||..|.||||||| | ..||||||||.. | ..|. .|||
lvsslklsvldllkll..ekaldlglleeefeellsvkplleysvallpenkdkNrykdilpydhsRVkl....degsdYInAsyvdgyssklprkfIat
QGPIPAAFPDFWRMIWEYNVPTIIMVTNLKEDDKIKCHQYWPSF---GAANYGSFQVTLKEVETVADYAIRTFQLQSLHGQgPIKEVRQYHFLVWPDHGV
||| | . |||||.||.||..|.|.|.| |....||.||||. | .|| |.|||...|. .|| .||..|. | .. . ..|...|.. ||||||
qgPlpntvedFwrmvweqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseevlddytvrtleltnlgdg.esrtvthfhytnWpdhgv
PQYATPLLSFQKRVRNHHkgKPGPMVVHCSAGVGRTGTFITIDTMIMKIDAEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAIMCRDT
|.....||.| ..||... ..||.|||||||||||||||..|... ...|| ||.|. |. .| .|..|||| .|| ||..|.|| .... |
Ppspeilldflelvrksl..pggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylflyralleylklklt
|
|||||||||
subfamily_PTPRB_pd | Subfamily PTPRB | 80-359 | 1.8e-98 | 324.2 | In-house | 6-287 (293) | alignment | ||
Range on Protein: 80-359
Range on HMM: 6-287/293.0
PLNVSDFIEMMALLQSNNSDRLEEEYPDIE-LEWNFTSYAAKLPINHGKNRYVNIIPYDHSRVTL-KPDGNPGSDYINASFIGGLNSPKDYIATQGPIPA
|.....| | .. ..... |. ||| ... .. . . ||.|..|. |||| ||.||||||| | . ....|||||||..| |.|||...||||||.|
piklekfeehvkkmkadsdlrfseeyeelkavgkdqavkaaelavnraknrytnilpydhsrvkLaalkdesgsDYinanyipgynsprefiatqGPlpe
AFPDFWRMIWEYNVPTIIMVTNLKEDDKIKCHQYWPSF-GAANYGSFQVTLKEVETVADYAIRTFQLQSlhgQGPIKEVRQYHFLVWPDHGVPQYATPLL
.. |||||.|| .. .|.|.|.| | |.||..|||. . .||. .|||.. |.. |..||..... . ...||||||. |||||||. ...||
tvddfWrmvwekkssiivmltqlvekgkvkCeeYWPadeepvlyGdikvtlvaeeeledwvirelkiek...ekeerkvrqyhftsWpdhgvPektktll
SFQKRVRNHH--KGKPGPMVVHCSAGVGRTGTFITIDTMIMKIDAEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAIMC
.| ..||... . . .|.|||||||||||||||..|... .|. | .|||| .| .| ||..||| .|| |.|...|. ..
dfvrtvreaiektaskrPivvhCsaGvGRtGtfialdrllqaieeedyvdifgivaelReeRnllvqtekqYifihqcvldllrk
|
|||||||||
0040438 | (Phosphotyrosine protein) phosphatases II | 85-392 | 1.8e-98 | 325.0 | In-house | 4-311 (317) | alignment | ||
Range on Protein: 85-392
Range on HMM: 4-311/317.0
DFIEMMALLQSNNSDRLEEEYPDIELEWNFTSYAAKLPINHGKNRYVNIIPYDHSRVTLKPDGN-PGSDYINASFIGGLNSPKDYIATQGPIPAAFPDFW
|... . .| .. .|.||. |. | |.|| |..||||..|.||||||| |.|.|. ..|||||||.. | | .. .|||||| | . |||
dlllalldllksdftalleefedllslkldtysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPlpntvedFw
RMIWEYNVPTIIMVTNLKEDDKIKCHQYWPSFGAANYGSFQVTLKEVETVADYAIRTFQLQSLhGQGPIKEVRQYHFLVWPDHGVPQYATPLLSFQKRVR
||.||..| .|.|.|.|.|....||.||||. . .|| |.|||...|. |.. .||.... | | .. .|...|.. |||||||.. ..||.| ..||
rmvweqgvtvivmLteleelgrekcaqYwplgetltygdftvtllseeelagitlrtlevedl.gdsesrtvthfhytgWpdhgvppspdllldfleavr
NHHKGKPGPMVVHCSAGVGRTGTFITIDTMIMKIDAEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAIMCRDTTIPAVHMATKIATLKEIAPSS
.. ....||..||||||||||||||....|.. .. || ||... |. .| .|...||| .|| ||. |.|| .....| .|| . ..|. |... . .
ealedpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleylkrkltlepaselklkllklliplald
GKTGFQSQF
. .. ....
dvklkekel
|
|||||||||
subfamily_PTPRG_pd | Subfamily PTPRG | 82-378 | 2.3e-97 | 321.5 | In-house | 2-304 (563) | alignment | ||
Range on Protein: 82-378
Range on HMM: 2-304/563.0
NVSDFIEMMALLQSNNSDRLEEEYPDIELEWNF---TSYAAKLPINHGKNRYVNIIPYDHSRVTLKPD-GNPGS-DYINASFIGGLNSPKDYIATQGPIP
.|..| . .| | ... ...||. ... | . . ... | |. ||||.||..||.|||.|.| |. .. |||||..| | . |..||||||..
pvkefakhvaslhadgdigfseefealqsetiskdldaehsqkpenkrKnRylnivaydrsRvklsplpgkkkklDYinAnyidGyqkskafiatqgplk
AAFPDFWRMIWEYNVPTIIMVTNLKEDDKIKCHQYWPSFGAANYGSFQVTLKEVETVADYAIRTFQLQSLH---GQG--PIKEVRQYHFLVWPDHGVPQY
| |||||||| || .|.|.|||.|. . ||..|||. .. .||..||||.| |..| |..||.... |. .. |.|||||. |||||||..
dtfddFWrmiWeqnvaiivmitnlvergrrkcdvYWPkdesetygalqvtlieeevlalytvrtlviknlklkkkkqcdteklvrqyhytkWPdhgvPeh
ATPLLSFQKRVRNHHKGKPGPMVVHCSAGVGRTGTFITIDTMIMKIDAEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAIMCRDTTIpavhMAT
..| |.| |. .| . ||.|||||||||||||.| .||.. .| .| .|..|.|.. .| ||..||| || ||| |.||||. ..| . .|.
slpvLifvkkssaankaeaGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvqteEqYiflhdalleaiasketel....lae
KIATLKE
.. ||.
qveelkn
|
|||||||||
0046845 | (Phosphotyrosine protein) phosphatases II | 105-363 | 6.7e-96 | 316.3 | In-house | 6-280 (284) | alignment | ||
Range on Protein: 105-363
Range on HMM: 6-280/284.0
YPDIE---LEWNFTSYAAKLPINHGKNRYVNIIPYDHSRVTLKPDGN--PGSDYINASFIGGL-----NSPKDYIATQGPIPAAFPDFWRMIWEYNVPTI
. . . .. ..|.|| |. ||||..|.||||||| ||. .. ..|||||||.. | ...| .|||||| | . |||||.||.||..|
feellsltvklllslsvallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqnvrvI
IMVTNLKEDDKIKCHQYWPSFG-AANYGSFQVTLKEVETVADYAIRTFQLQSLHGQGPIKEVRQYHFLVWPDHGVPQYATPLLSFQKRVRNHHK--GKPG
.|.|.| |....||.||||. | .|| |.|||...|. || .||..|. |. |. ..|...|.. |||||||.....||.| . ||.... ...|
VmltelvengrekcaqYwplegevltygdftvtllseevkddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrellenlpggg
PMVVHCSAGVGRTGTFITIDTMIMKIDAEG---IVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAIMCRDTT
|.|||||||||||||||..|... ...|| ||... |. .| .|..|||| .|| |...|.||..... |
pivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleylklkltl
|
|||||||||
subfamily_PTPRK_pd | Subfamily PTPRK | 78-394 | 1.8e-95 | 314.4 | In-house | 1-314 (314) | alignment | ||
Range on Protein: 78-394
Range on HMM: 1-314/314.0
HPPLNVSDFIEMMALLQSNNSDRLEEEYPDIELEWNftsyAAKLPINHGKNRYVNIIPYDHSRVTLKP-DGNPGSDYINASFIGGLNSPKDYIATQGPIP
|| . | | .. .|||. ... . ||| . |. ||| |. |||. .|..||.|||.|.. ||.| ||||||..| . . |. .|.||||..
hpairvadllqsiallkraegygfkeeyeslfegwd....aakkdenreknrsgdilaydrsrvflitidgdpssdyinaalidsykrpaafivtqgPlq
AAFPDFWRMIWEYNVPTIIMVTNLKEDDKIKCHQYWPSFGAAnYGSFQVTLKEVETVADYAIRTFQLQS-LHGQGPIKEVRQYHFLVWPDHGVPQYATPL
||||.....| .|.|.|.|.| ..|| .||| . || ..|.| |.|. |.. .|.|... .|| |.||||..|| ||||.||..|| |
etvkdfWrlvydencasivmltelvevgrvkClkyWPedtev.ygdikvelvetellaelvvrifrveklargqeeirevrqfqflgWpdhdvPvsatgl
LSFQKRVRNHHKGKPGPMVVHCSAGVGRTGTFITIDTMIMKIDAEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAIMCRDTTIPAVHMATKIAT
|.. .|| .... . |..||||||| |||||||.||... |. ||.||.|| |. .| . ||.| || |.. .|||| .| .|.||. .. .
lklvrrvkksqeeeaGrivvhCsaGaGrtGtfiaidivldmieregvvdvfnavktlrsrkvnmveteeqykfiydvileaclcgetaipvsefkalyle
LKEIAPSSGKTGFQSQFET
... | . . .. .|.|
sirldpqtnssqlkeefqt
|
|||||||||
0036941 | (Phosphotyrosine protein) phosphatases II | 94-369 | 6.4e-95 | 313.1 | In-house | 8-289 (297) | alignment | ||
Range on Protein: 94-369
Range on HMM: 8-289/297.0
QSNNSDRLEEEYPDIE-LEWNFTSYAAKLPINHGKNRYVNIIPYDHSRVTLkpdGNPGSDYINASFIGGLNSPKDYIATQGPIPAAFPDFWRMIWEYNVP
..... .|..|. .. | .... ..|.|| | |||| .|.||||.|| | ...||||||||.. | . .. .|||||| | . |||||.||.||.
kllflalllkefeellpllllgslsvallpenleknRykdilpydhtRVkl...ddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqnvt
TIIMVTNLKEDDKIKCHQYWPSF--GAANYGSFQVTLKEVET--VADYAIRTFQLQSLhGQGPIKEVRQYHFLVWPDHGVPQYATPLLSFQKRVRNHHKG
.|.|.|.| |....||.||||. . .|| |.|||..||. .|| .||.... . | |. ..|...|.. |||||||.....||.| ..||...|
vIvmltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdt.gngesrtvthfhytgwpdhgvpespaslldfielvrkvlkl
--KPGPMVVHCSAGVGRTGTFITIDTMIMKID---AEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAIMCRDTTIPAVHM
..||..|||||||||.||||..|.|.. .. || |||...|. .| .|. .||| .|| ||..|.|| .....| .|.. .
lpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallellkkkltkepllkl
|
|||||||||
subfamily_PTPRD_pd | Subfamily PTPRD | 403-656 | 1.8e-94 | 312.4 | In-house | 36-286 (564) | alignment | ||
Range on Protein: 403-656
Range on HMM: 36-286/564.0
DDFDCSIAQLSDNLAKSRVKEHLPPNDYRVVLSTKNY--DSDYICASYVDGYRQRSAFIATQGPMKNTAGDFWRMVWEMKSMIIIMLTNTEENGEEQSVQ
. | .. |. . | || |... .. . |||||. . .|||| ||..||||.| |.||||||...| |||||||| .| .|.|||..||.|... .
qqftweaankpaNkaKNRyanivaYdhsRVvLskvegdegsDYINAsfidgyrkrkayIAtqgPlaetiedFWRmvweqnsstiVmltkleEkgkvkchk
YWPVNpNeEDMYGSFNvVALPEERALPDYIVRKFKLsHSKNPDDSRTITHFQYINWPSTSCPKEATSMIDLVADVVRIQrKSGNGPITVHCSDGLGRTGT
||| . . . ||.. | | || | ||..|.||| . |. ..||....|....||.. |..|||..||. .| ... ....|||.|||| | |||||
YWPek.g.tetygelt.Vtleeeeeladyeirtfkl.kkkkssesreVrqFhFtsWPdhgvpesatslLdlirkvraln.epdagPivVhCSaGVGRTGt
FCAMFTVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFVNTFDN
|... .|||.|.|...|....||.|| ||. | .|| |||.| ||... ...
fividamlerikeektvDiyqyvkalrkqRnamVqteeQYiFiheailealacgnt
|
|||||||||
0045450 | (Phosphotyrosine protein) phosphatases II | 76-359 | 1.8e-93 | 308.9 | In-house | 4-306 (307) | alignment | ||
Range on Protein: 76-359
Range on HMM: 4-306/307.0
PNHPPLNVSDFIEMMALLQSNNSDRLEEEYPDIELEWNF---TSYAAKLPINHGKNRYVNIIPYDHSRVTLKPDGN--PGSDYINASFI--------GGL
| ...... ... ...||. .. .|..|. .. .. | . ..|.|| |. ||||..|.||||.|| |.. .. ..|||||||.. .|
plslfidalkllllvllllldfltgllkefekllsvtvfllgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgy
NSPKDYIATQGPIPAAFPDFWRMIWEYNVPTIIMVTNLKEDDKIKCHQYWPSFGAA-NYGSFQVTLKEVETVADYAIRTFQLQSLHGQGPIKEVRQYHFL
.... .|||||| | . |||||.||..| .|.|.|.|.|....||.||||. | .|| |.|||...|. ..| .||. .. |.| |. .|...|..
dlkrkfIatqgPlpetvedFwrmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhyt
VWPDHGVPQYATPLLSFQKRVRNHHKG--KPGPMVVHCSAGVGRTGTFITIDTMIMKIDAEGI---VDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEA
|||||||.. .||.| ..||.... |.||..||||||||||||||....|. ...||. ||... |. .| .| .||. .|| ||..|.||
gwpdhgvppsfeelldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeallel
IMC
...
llk
|
|||||||||
subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 88-364 | 3.5e-93 | 307.1 | In-house | 16-297 (298) | alignment | ||
Range on Protein: 88-364
Range on HMM: 16-297/298.0
EMMALLQSNNSDRLEEEYPDIELEWN----FTSYAAKLPINHGKNRYVNIIPYDHSRVTLKP-DGNPGSDYINASFIGGLNSPKDYIATQGPIPAAFPDF
.. | .... ....|. .. . ... .|. | |. |||| .||..|.||| |. |.. ||||||||. . . . .||||.|..... ||
klaavkkkkkltgyalefqrlnsvsseieeeekevarkpenkkkNRyadiialdssRvvLekedadeesdYiNAsflhaykgrnafiatqaPltetvedF
WRMIWEYNVPTIIMVTNLKEDDKIKCHQYWPSFGAANYGSFQVTLKEVETVADYAIRTFQLQSLHGQgPIKEVRQYHFLVWPDHGVPQYATPLLSFQKRV
|||..|... ||.|.|||.| ||.|.|.|||. |...||...|.|.. |. ||...|...... . . .|||| || .|||.|||..|| .| . ..|
WrmvteedigtiVmltnleeldktkyhkywPdegketygeitvsllskeefadlivrklkvskkkee.kerevrqlhftsWpdkgvpenatsvldllrkv
RNhHKGKPG--PMVVHCSAGVGRTGTFITIDTMIMKIDAEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAIMCRDTTI
| .. . | |..|.|||||||.|||| ||... .. .| ||.|. |. .| | .||| .|| |...|.|||. . .. |
ra.sqqqagnkpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavlealdsfndei
|
|||||||||
subfamily_PTPRA_pd | Subfamily PTPRA | 77-392 | 6.4e-93 | 306.2 | In-house | 10-330 (330) | alignment | ||
Range on Protein: 77-392
Range on HMM: 10-330/330.0
NHPPLNVSDFIEMMALLQSNNSDRLEEEYPDIEL-EWNFTSYAAKLPINHGKNRYVNIIPYDHSRVTLKP-DGNPGSDYINASFIGGLNSPKDYIATQGP
...|| | .. | . ..... .. ||. . . . | .|. |. |||.|||.|||.||| | . .|.. ||||||||| | . . .||.|||
kyfplpvekleeeirirsaddnklfreefnalPagpiqatlelaskeenkeknrvvnilPydfsrvilsvkeGveesdyinasfidGykekdkfiaaqGP
IPAAFPDFWRMIWEYNVPTIIMVTNLKEDDKIKCHQYWPSFGAANYGSFQVTLKEVETVADYAIRTFQLQSLHGQ---GPIKEVRQYHFLVWPDHGVPQY
. ||||||||.. ||.|.|.||| .. ||.||||. |. || .|...... . ||..| | .| | . . . |||.|| ||| |||
keetvedfwrmiweqksativmltelkerkeekcaqywPdeGlvtyGnirvevedetvlvdytvrkflvqqlpdatrekksrlvrqfhftswPdvGvPfe
ATPLLSFQKRVRNHHKGKPGPMVVHCSAGVGRTGTFITIDTMIMKIDAEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAIMCRDTTIPAVHMAT
. .|.. |.|.. .. . ||.|||||||||||||||..|... .. ||..||.|.||. .| | |||| || |.....|| . || . .. . .
piGmlkllkkvkklnqqsagpivvhcsaGvGrtGtfivldavlervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvlleyylygdteldvsslek
KIATLKEIAPSSGKTGFQSQF
.. .|.. .. |.|.. .|
hlqklynkitgtdkigleeef
|
|||||||||
0039614 | (Phosphotyrosine protein) phosphatases II | 76-362 | 2.1e-92 | 305.0 | In-house | 9-294 (297) | alignment | ||
Range on Protein: 76-362
Range on HMM: 9-294/297.0
PNHPPLNVSDFIEMMALLQSNNSDRLEEEYPDIELEWNfTSYAAKLPINHGKNRYVNIIPYDHSRVTLKPDGN--PGSDYINASFIGGLNS-PKDYIATQ
...| .| . . |.. |.. .|..|. .. . |.|| | ||||..|.||||||| ||| .. ..|||||||.. | . ....||||
lesipiplsvldlllllekansktllllefeellslkp.dysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIatq
GPIPAAFPDFWRMIWEYNVPTIIMVTNLKEDDKiKCHQYWPSFGAaNYGSFQVTLKEVETVADYAIRTFQLQSlhgQGPIKEVRQYHFLVWPDHGVPQYA
|| | . |||||.||..|..|.|.|.|.|... ||.||||. | .|| |.|||..||. ..| .||. .. |. ..|...... |||||||...
gPlpetvedFwrmvweqgvtvivmLtklvelgr.kcaqywpeegg.tygdftvtllkvehldgytvrtlevtn...ngesrtvthfqytgwpdhgvppsl
TPLLSFQKRVRNHHKG--KPGPMVVHCSAGVGRTGTFITIDTMIMKIDAEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAIMCRDT
. ||.| . ||.... |.||..||||||||||||||....|. .. || ||... |. .| .|...||| ||| ||..|.|| .....|
ellleflelvrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydallellkrklt
|
|||||||||
0047943 | (Phosphotyrosine protein) phosphatases II | 94-357 | 2.9e-92 | 304.3 | In-house | 7-272 (273) | alignment | ||
Range on Protein: 94-357
Range on HMM: 7-272/273.0
QSNNSDRLEEEYPDIEL-EWNFTSYAAKLPINHGKNRYVNIIPYDHSRVTLkpdGNPGSDYINASFIGGLNSPKDYIATQGPIPAAFPDFWRMIWEYNVP
.......|.||. .. ...| ..|.|| |. |||| .|.||||||| | |..||||||||.. | |... .|||||| | . |||||.||.||.
kllgltllleefelllslkplltysvallpenkdknrykdilpydhsrvkl...gdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvweqnvr
TIIMVTNLKEDDKIKCHQYWPSFG---AANYGSFQVTLKEVETVADYAIRTFQLQSLHGQGpIKEVRQYHFLVWPDHGVPQYATPLLSFQKRVRNHHKG-
.|.|.|.| |....||.||||. | .|| |.|||...|| .|| .||..|..|. . ..|...|.. |||||||.. ..||.| . ||....
viVmLtelvelgrekcaqYwpleggelsltygkftvtllseetkddytvrtleltnlgtge.srtvthfhytgwpdhgvppslesllefielvrkaleal
-KPGPMVVHCSAGVGRTGTFITIDTMIMKIDAEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAI
..||.|||||||||||||||..|... . .|| ||... |. .| .| .|||| .|| ||..|.|| .
psngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyealleyl
|
|||||||||
subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 78-393 | 9e-92 | 302.3 | In-house | 3-315 (315) | alignment | ||
Range on Protein: 78-393
Range on HMM: 3-315/315.0
HPPLNVSDFIEMMALLQSNNSDRLEEEYPDIELEWNFTSYAAKLPINHGKNRYVNIIPYDHSRVTL-KPDGNPGSDYINASFIGGLNSPKDYIATQGPIP
| |. . ..| .| ... . ....| | . || |. ||||.|||.||.||| | . .|.|||.||.|| | | .. |||.||| .
hqpipldqlityvaqkkastkngfkqdyesipggqlhpldvakkienkqknryiniiaydksrvqlpllendphsdyvnanfidGynkkrryiaaqgpnv
AAFPDFWRMIWEYNVPTIIMVTNLKEDDKIKCHQYWPSFgAANYGSFQVTLKEVETVADYAIRTFqlqSLHGQGPIKEVRQYHFLVWPDHGVPQYATPLL
|. ||||...|... .|.|.||| |..| |. .||| || . ||.|. | .|..||. | . |.|| |.|. ||| |||.|..||.
asvkdfwrlvfeedigkivmltnlvegekrkaekywpdk.kviyGkitvtrkseevnteytvrtl...svvfgdnirevvqlhytswpdmgvpkytiplm
SFQKRVRNHHKGKPGPMVVHCSAGVGRTGTFITIDTMIMKIDAEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAIMCRDTTIPAVHMATKIATL
. ..|. ||. . |..||||||||||||||||.|... ...|| ..|..||..|.| | |||.| ||.|.. |.||...| ||.| . .|
nlirtvkqhhtnsvgaivvhcsaGvGrtGtfitldavldqaeaenaidvynfitgvrqnrikmvqvaeqyqfiydalletfvcgdtsiaqdlylqrydsl
KEIAPSSGKTGFQSQFE
.| .| | .| |||
lapspdtgstllqeqfe
|
|||||||||
0043336 | (Phosphotyrosine protein) phosphatases II | 80-356 | 4.8e-91 | 300.3 | In-house | 1-276 (278) | alignment | ||
Range on Protein: 80-356
Range on HMM: 1-276/278.0
PLNVSDFIEMMALLQSNNSDRLEEEYPDIELEWNFTSYAAKLPINHGKNRYVNIIPYDHSRVTLKP-DGNPGSDYINASFIGGLNSPKDYIATQGPIPAA
|..|.|...... | |. .|..|. .. . .| . |.|| |. ||||..|.||||||| |.. .| ..|||||||.. | | |...|||||| |
pisvkdllkallelllnlktllllefeellsfkldtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpet
FPDFWRMIWEYNVPTIIMVTNLKEDDKIKCHQYWPsFGAANYGSFQVTLKEVETVADYAIRTFQLQSlHGQGPIKEVRQYHFLVWPDHGVPQYATPLLSF
. |||||.||..|.||.|.|.|.|....||.|||| | .|| |.|||...|. .|| .||. . .| |. ..|..||.| ||||||| ..||.|
vedFwrmvwelgvttivmLtelvelgrvkcaqYwp.ggsltygdftvtllkeehlddytvrtlevtn.lgdgesrtvthyhylgwpdhgvpeslsllldf
QKRVRNHHKGKPGPMVVHCSAGVGRTGTFITIDTMIMKIDAEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEA
|.||.. . ..||..||||||||||||||....... .. || ||... |. .| .| .||| ||| ||..|.||
lkavrealedsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyealley
|
|||||||||
0050432 | (Phosphotyrosine protein) phosphatases II | 363-657 | 1.3e-90 | 299.2 | In-house | 19-305 (308) | alignment | ||
Range on Protein: 363-657
Range on HMM: 19-305/308.0
TIPAVHMATKIATLKEIAPSSGKTGFQSQFETLESSSPtddDFDCSIAQLSDNLAKSRVKEHLPPNDYRVVLstkNYDSDYICASYVDGY--RQRSAFIA
. . .. . . || . . ...... .||.| | | ....|.|.| .| | | | || ||.| . .||||.||||||| ... .|||
ilvsslklsvldllkllekaldlglleeefeellsvkp...lleysvallpenkdkNrykdilpydhsRVkl...degsdYInAsyvdgyssklprkfIa
TQGPMKNTAGDFWRMVWEMKSMIIIMLTNTEENGEEQSVQYWPVNPN-EEDMYGSFNVVALPEERaLPDYIVRKFKLSHSKNPdDSRTITHFQYINWPST
||||..|| .|||||||| .. .|.|||...||| |. |||| ... . .|| | | | || |.||.||...|...... .|||.|||.|.|||
tqgPlpntvedFwrmvweqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseev.lddytvrtleltnlgdg.esrtvthfhytnWpdh
SCPKEATSMIDLVADVVRIQrksGNGPITVHCSDGLGRTGTFCAMFTVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFVNTFDNY
..| ......|.. | . . ..||| ||||.|.||||||.|. ..||.|..|. .|||..||.|| |||| |.. .||.|...|.||..... ..
gvPpspeilldflelvrksl...pggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylflyralleylklkltk
|
|||||||||
subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 91-357 | 3.8e-90 | 296.8 | In-house | 13-279 (288) | alignment | ||
Range on Protein: 91-357
Range on HMM: 13-279/288.0
ALLQSNNSDRLEEEYPDI-ELEWNFTSYAAKLPINHGKNRYVNIIPYDHSRVTLKP-DGNPGSDYINASFIGGLNSPKDYIATQGPIPAAFPDFWRMIWE
| . .| . ..||| . .|| . .. |..|. |. |||| ||.|||. || || . ..|.||||||.| | .. | |||||||.... |||....|
akksarnrtgfseeynsLaalektksvtagrlavnakknRyrnilpyDekrvklkkleeeagaDYinasyidgekkkkkyiatqgPladtvndfWelvye
YNVPTIIMVTNLKEDDKIKCHQYWPSFGA-ANYGSFQVTLKEVETVADYAIRTFQLQslhGQGPIKEVRQYHFLVWPDHGVPQYATPLLSFQKRVRNHHK
... ||.|.|.| |..| ||..|||. . ||||..|||.|.... |. |.. |. .. |. ||..|.|||||||. ..||| . . | . ..
nktstivmltelveggktkCeeYWPdadkpknyGsvtvtlveskeledfvlrkllle...kkkteleitqyqylaWpdhgvPeskapllellrqvkvanq
GKPGPMVVHCSAGVGRTGTFITIDTMIMKIDAEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAI
. ||..||||||||||||||..|..| ....| .|....| .| |. .||| .|| |.....|. |
adtgpiivhCsaGvGrtgtFialdalidaveeedyiDvagtvaklRkqRallvqtlkqYefiyevllsli
|
|||||||||
subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 101-401 | 4.1e-90 | 297.3 | In-house | 20-320 (515) | alignment | ||
Range on Protein: 101-401
Range on HMM: 20-320/515.0
LEEEYPDIELEWNFTSYAAKLPINHGKNRYVNIIPYDHSRVTL-KPDGNPGSDYINASFIGGLNSPKDYIATQGPIPAAFPDFWRMIWEYNVPTIIMVTN
. ||. |. . |. ||. |||| ||.||| .|| | . || |||.|||.| .... | |||.||| .|. ||||.....|| ||.|||.
fseefhdlpgpniypqtvaqeeinfkknryknilPydsvrvklevindnPhsdyfnasyipsfdndkayiasqgPnkasvddfWrlvlqenvttiamvtk
LKEDDKIKCHQYWPS--FGAANYGSFQVTLKEVETVADYAIRTFQLqsLHGQGpIKEVRQYHFLVWPDHGVPQYATPLLSFQKRVRNHHKGKPGPMVVHC
|||.||||| .||| . ..||..| | .|. .. .|.... |.|. .. | |.|| |||.|||. .. || . | |. | |...||
lkegdkikcgkyWPdkpgdsvkfGsikvelvsleactggikrkltv..lkgdd.srtvtqfhfteWPdkGvpkhtssllklikevkadhgqythpliihc
SAGVGRTGTFITIDTMIMKIDAEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAIMCRDTTIPAVHMATKIATLKEIAPSSGKTGFQSQFETLES
|||||||| .|.|| .. .. .||.||||. .| | |.||| || |.. |.|| .. |.| || .|.. .. |. |.. . .|.||.|
saGvGrtGvvisidsvvahakttrmvdvfnfvtnirqkrpylvqtqeqyafiygavledllwrntlipvihftdhlqdlhssgdgrgrskmtkefqtlks
SSPT
|
lcpd
|
|||||||||
subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 362-657 | 1.3e-89 | 295.4 | In-house | 3-296 (298) | alignment | ||
Range on Protein: 362-657
Range on HMM: 3-296/298.0
TTIPAVHMATKIATLKEIAPSSGKTGFQSQFETLESSSPTDDDFDCSIAQLSDNLAKSRVKEHLPPNDYRVVLST--KNYDSDYICASYVDGYRQRSAFI
| | | .. ... |... .. . ||....|..|.| | . ... ..|. ..| | | . .. . ||||.. .. .|||| ||....|..|.|||
teieaedlkaalqklaavkkkkkltgyalefqrlnsvsseieeeekevarkpenkkkNRyadiialdssRvvLekedadeesdYiNAsflhaykgrnafi
ATQGPMKNTAGDFWRMVWEMKSMIIIMLTNTEENGEEQSVQYWPVNpnEEDMYGSFNVvALPEERALPDYIVRKFKLSHSKNPdDSRTITHFQYINWPST
|||.|...| ||||||.| .. |.||||.|| .. . .||| . ... ||...| | .. |.||||.|.|..|. ..|.. ......||.
atqaPltetvedFWrmvteedigtiVmltnleeldktkyhkywPde..gketygeitv.sllskeefadlivrklkvskkkee.kerevrqlhftsWpdk
SCPKEATSMIDLVADVVRIQRKSGNGPITVHCSDGLGRTGTFCAMFTVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFVNTFDNY
. |..|||..||...| . |...|| |..|.||.| ||.|||.|. .||||.|.|||.||| .||.||..||| |. .|| ||..| ||....|...
gvpenatsvldllrkvrasqqqagnkpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavlealdsfnde
|
|||||||||
subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 92-358 | 3e-89 | 293.8 | In-house | 8-277 (281) | alignment | ||
Range on Protein: 92-358
Range on HMM: 8-277/281.0
LLQSNNSDRLEEEYPDIEL-EWNFTSYAAKLPINHGKNRYVNIIPYDHSRVTLKPD-GNPGSDYINASFIGGLNSPKDYIATQGPIPAAFPDFWRMIWEY
|..|.. . ||| ... . . |. |.| . | ||||.||. ||..||...|. | .|||||.|. |....|.|||||||.||.. .||.|.||.
qlsqndnaGfieeyeklaaigvdntataskadenvlknrYsnivaYDatrvkvtpneenkntDYinanfvpgykgekeyiatqgPvPaslvafWqmvweq
NVPTIIMVTNLKEDDKIKCHQYWPSFG-AANYGSFQVTLKEVETVADYAIRTFQLqsLHGQGPIKEVRQYHFLVWPDHGVPQYATPLLSFQKRVRNHHKG
.| .|.|||. | .|.|||.||| . .|| ..|. .. |. | |. |.|.| . .|. .||.| ... |||||||. .. ||.|.| |.. ..
kvsaivmvtreieagklkChrYWPddnselkygdvtvkstaeeekatyierkfkl..eresgetreveqlaytaWPdhGvPattkellefrkevlkltek
-KPGPMVVHCSAGVGRTGTFITIDTMIMKIDAE-GIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAIM
. |.|.|||||||||||.|..|... ...|| .|. . |. .| ||.|||| ||.|...|.|.|..
ktkaplvihCsaGvGrtGtyialDrlvkaveaeleeldvkavvaelrkernlmvqtvvqyefvykavldald
|
|||||||||
subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 82-377 | 7.5e-89 | 292.9 | In-house | 5-303 (305) | alignment | ||
Range on Protein: 82-377
Range on HMM: 5-303/305.0
NVSDFIEMMALLQSNNSDRLEEEYPDIELEwNFTSYAAKLPINHGKNRYVNIIPYDHSRVTLKPDGNPG-SDYINASFIGGLNSPKDYIATQGPIPAAFP
...|. . . ...... ||..| . | . . | |. |||...|...|..|. |... . . |||||||.. | .. | ||..|||..
alddlaayikearvysdkgleaqykslyee.eesidvgkkeankaknrlkeitlldddriiltekeslddsdyinasyvdgykrkkkyivaqgPlkntva
DFWRMIWEYNVPTIIMVTNLKEDDKIKCHQYWPSFGAA--NYGSFQVTLKEVETVADYAIRTFQLQSLHGQGPIKEVRQYHFLVWPDHGVPQYATPLLSF
||||.|.|. | ||.|.|.|.|..| ||.|||| . ..|.|.|.||. .|..|| .| ... ... . | ||.. ||||||||.|| |||.
dfWrliveekvstivmltklveggkdkCrqYWpesktekkefgefsvelksektasdyieRklkisiededkesrtvlqyqltdWPdhGvpqfatsllsl
QKRVRNHHKGKPG-PMVVHCSAGVGRTGTFITIDTMIMKIDAEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAIMCRDTTIPAVHMATKIATLK
|||....| | |..|||||||||||.||..| .. .. .|..||.|. .. .| | .|||| ||.||| |. | | | || | . .. ||
ikrvqkdqkkdkgvpllVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkmvqtldqYvflhdaldelitcgdtsiigsnlrarvnklk
|
|||||||||
0051299 | (Phosphotyrosine protein) phosphatases II | 364-651 | 3.1e-87 | 287.9 | In-house | 5-286 (288) | alignment | ||
Range on Protein: 364-651
Range on HMM: 5-286/288.0
IPAVHMATKIATLKeiapSSGKTGFQSQFETLESSSPTdddFDCSIAQLSDNLAKSRVKEHLPPNDYRVVLSTKNY--DSDYICASYVDGYRQRSAFIAT
|.. ... . .|. .|.||.. .||.| | |. ...|.|.| || | | . || .. ||.||. . .||||.|||.|||.. .||||
isveellklvlkll....angltglleefeellsllpd...ltlsaallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyidgynlkrkfIat
QGPMKNTAGDFWRMVWEMKSMIIIMLTNTEENGEEQSVQYWPVnpNEEDMYGSFNVVALPEERaLPDYIVRKFKLSHSK---NPDDSRTITHFQYINWPS
|||..|| .|||||||| .. .|.|||...|.| |.. |||| .. .|| . | | || |.||.||...... . .. |||.|||.|.|||
qgPlpntvedFWrmvweqnvrvIvmltklvelgrekcaqYwpl..ggsltygditvtllseev.lddytvrtlevtnldlldgdgesrtvthfhytnwpd
TSCPKEATSMIDLVADVVRIQRkSGNGPITVHCSDGLGRTGTFCAMFTVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFV
..| .....|.. .| . .. ||.||. ||||.|.||||||.|....||.|..|...||...||.|| |||| |. .||.|...|.||..
hgvpdspellldflrlvrkala.sgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyealleyl
|
|||||||||
subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 382-655 | 3.4e-87 | 287.5 | In-house | 19-287 (319) | alignment | ||
Range on Protein: 382-655
Range on HMM: 19-287/319.0
SSGKTGFQSQFETLESSSPTdddfDCSIAQLSDNLAKSRVKEHLPPNDYRVVLSTK--NYDSDYICASYVDGYRQRSAFIATQGPMKNTAGDFWRMVWEM
|.|.|... .|..|. .... . . |. .| | | .. |. . |||||. .|||| ||..|||..|..|||||.|..|| ||||||||
stgetllekefkllkeavnd....tfdsaskeenkkknryqnilaydrtrvvlseldgvegsdyinasfidgyqerekfiatqaPlentiedfWrmvWee
KSMIIIMLTNTEENGEEQSVQYWPVNpnEEDMYGSFnVVALPEERALPDYIVRKFKLSHSKNPDDSRTITHFQYINWPSTSCPKEATSMIDLVADVVRIQ
.|.|..|||. |... . .||| . . || . .| | ||. | |||.||.|| . .. ..|...|||| .|| |..|||..||. .. . .
essivvmltklveklkvklkkywpee..nfeeyGrl.ivtleeeeeledyiirklklnkkssevetRevkhfqyteWpdhdvPekatslldllkrirksr
RKSGNGPITVHCSDGLGRTGTFCAMFTVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFVNTFD
.|. .|||.||||.| ||||||.... .|||.| |.|.||||||..||.||. |. .||.||..| ||.|...|
ektqsgPivvhCsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyealleaveagd
|
|||||||||
0046845 | (Phosphotyrosine protein) phosphatases II | 387-657 | 1.1e-86 | 286.0 | In-house | 1-280 (284) | alignment | ||
Range on Protein: 387-657
Range on HMM: 1-280/284.0
GFQSQFETLESSSPTDDdFDCSIAQLSDNLAKSRVKEHLPPNDYRVVLSTKNYD---SDYICASYVDGY-----RQRSAFIATQGPMKNTAGDFWRMVWE
|.. .||.| | .. ...|.|.| || | | | || .. ||.|.. . | |||| ||||||| ... .|||||||..|| .||||||||
gleeefeellsltvkll.lslsvallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvwe
MKSMIIIMLTNTEENGEEQSVQYWPVNpNEEDMYGSFNVVALPEERaLPDYIVRKFKLSHSKNPDDSRTITHFQYINWPSTSCPKEATSMIDLVADVVRI
.. .|.|||...||| |. |||| . .| .|| | | | || .||.||...|.. . .. |||.|||.|..|| ..| ......... .| ..
qnvrvIVmltelvengrekcaqYwple.gevltygdftvtllseev.kddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrel
QRK-SGNGPITVHCSDGLGRTGTFCAMFTVLERLKAEQ---VIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFVNTFDNY
... .|.||| ||||.|.||||||.|. ..||.|..|. ..||...|| || ||||.|. .||.|...|.||..... ..
lenlpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleylklkltl
|
|||||||||
DSPc_SM00195 | 115-357 | 2.4e-86 | 284.7 | In-house | 17-262 (263) | alignment | |||
Range on Protein: 115-357
Range on HMM: 17-262/263.0
TSYAAKLPINHGKNRYVNIIPYDHSRVTLKPDG-NPGSDYINASFIGGLNSPKDYIATQGPIPAAFPDFWRMIWEYNVPTIIMVTNLKEDDKIKCHQYWP
.. |. . |. |||| ||.||||.|| ||.. ..|||||||..| | |..|.||||||| | . |||||.|| .|..|.|.|. .|..|.||..|||
etteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengkekcdrywp
SF--GAANYGSFQVTLKEVETVA-DYAIRTFQLQSLHGqGPIKEVRQYHFLVWPDHGVPQYATPLLSFQKRVRNHHKGKPGPMVVHCSAGVGRTGTFITI
. | ..|...|.|.|||.. .. .||..|. ..|.||.. |||||||. ....|.. . |..... . ||.||||||||||||||.||
eesggketfgkisvklvevekkkdeiilrtleltkegk.eetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivVhCsaGvgRtgtfvti
DTMIMKIDAEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAI
|... |...| ||||. |. .| | |||| || |...||||.|
diilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi
|
|||||||||
PTPc_SM00194 | 115-357 | 2.4e-86 | 284.7 | In-house | 17-262 (263) | alignment | |||
Range on Protein: 115-357
Range on HMM: 17-262/263.0
TSYAAKLPINHGKNRYVNIIPYDHSRVTLKPDG-NPGSDYINASFIGGLNSPKDYIATQGPIPAAFPDFWRMIWEYNVPTIIMVTNLKEDDKIKCHQYWP
.. |. . |. |||| ||.||||.|| ||.. ..|||||||..| | |..|.||||||| | . |||||.|| .|..|.|.|. .|..|.||..|||
etteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengkekcdrywp
SF--GAANYGSFQVTLKEVETVA-DYAIRTFQLQSLHGqGPIKEVRQYHFLVWPDHGVPQYATPLLSFQKRVRNHHKGKPGPMVVHCSAGVGRTGTFITI
. | ..|...|.|.|||.. .. .||..|. ..|.||.. |||||||. ....|.. . |..... . ||.||||||||||||||.||
eesggketfgkisvklvevekkkdeiilrtleltkegk.eetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivVhCsaGvgRtgtfvti
DTMIMKIDAEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAI
|... |...| ||||. |. .| | |||| || |...||||.|
diilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi
|
|||||||||
subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 102-395 | 2.9e-86 | 284.2 | In-house | 22-315 (315) | alignment | ||
Range on Protein: 102-395
Range on HMM: 22-315/315.0
EEEYPDIELEWNFTSYAAKLPINHGKNRYVNIIPYDHSRVTL-KPDGNPGSDYINASFIGGLNSPKDYIATQGPIPAAFPDFWRMIWEYNVPTIIMVTNL
||. |. . .|. .||. |||| ||.|.|..|| | | .| |||||||.| .... | |||.||| .|. |||||.....| ||.|||..
seefhdlpdPdiyrqrvaretinfkknryknilPldsarvkleviddsPdsdyinasyiksvdddkayiasqgPlkasvddfwrmvlqekvttivmvtkk
KEDDKIKCHQYWPS--FGAANYGSFQVTLKEVETVADYAIRTFqlqSLHGQGPIKEVRQYHFLVWPDHGVPQYATPLLSFQKRVRNHHKGKPGPMVVHCS
.|.||||| |||| ....||..|.| ..|. .| .| . . . | |..| |||.||.. .. || . | |. .. | ...||||
qegdkikcrqywPdrkadsvefGsikvellsleadtdgvarkl...vtrkseesrtvtqfqftewPdkGvdkqtssllklikevkadngkkefsllvhcs
AGVGRTGTFITIDTMIMKIDAEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAIMCRDTTIPAVHMATKIATLKEIAPSSGKTGFQSQFETL
||||||| .|.|| .. .| . ||.||||. .| | |.||| .| |.. |.|| .. |.| |. .|.. .. |. . ||.. . .||||
aGvGrtGvvisidevvaqikrtrsvdvfnfvknlrakrpylvqteeeyafiydavledllwrntlilvihftdhlqdlhtsvdgsgrskmtkefetl
|
|||||||||
subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 118-359 | 4.8e-86 | 283.9 | In-house | 55-293 (319) | alignment | ||
Range on Protein: 118-359
Range on HMM: 55-293/319.0
AAKLPINHGKNRYVNIIPYDHSRVTLKP-DGNPGSDYINASFIGGLNSPKDYIATQGPIPAAFPDFWRMIWEYNVPTIIMVTnlkeddKIKCHQYWPSFG
| |. | |||..||...|...| |.. .| .||||||||. | ... |||.||| . . ||||||||||. ||...| | || |||| .
fanldqnkdknriinilafdknvvklerliGeefsdyinasfvtGyqrkdkyiaaqGPldntladfWrmiweyncstivllt......kdkcsqywplki
AANYGSFQVTLKEVETVADYAIRTFQLQSLHGQGPIKEVRQYHFLVWPDHGVPQYATPLLSFQKRVRNHHK--GKPGPMVVHCSAGVGRTGTFITIDTMI
... |.| .. || |.|..| ..| . |....|.||| |||.|||.|...|. . |.|| .. .. ..||||||||||||..|..|...
vikeerfkvkvdsveetaeyvvrdielsedgkekdirkitqfhflGwpdvGvpdypsdlmrlvkkvrhltskenhranivvhcsaGvGrtGvyivldvll
MKIDAEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAIMC
... | ||..||||..| || .|| || |.. |.|| .
drmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleehlf
|
|||||||||
0036941 | (Phosphotyrosine protein) phosphatases II | 376-656 | 6.8e-86 | 283.5 | In-house | 3-282 (297) | alignment | ||
Range on Protein: 376-656
Range on HMM: 3-282/297.0
LKEIAPSSGKTGFQSQFETLessSPTDDDFDCSIAQLSDNLAKSRVKEHLPPNDYRVVLstKNYDSDYICASYVDGYRQRSAFIATQGPMKNTAGDFWRM
|| . ...........||.| | ....|.|.| .|| | | | || .. ||.| .. .||||.|||||||.. .|||||||..|| .|||||
lkllekllflalllkefeel...lpllllgslsvallpenleknRykdilpydhtRVkl..ddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrm
VWEMKSMIIIMLTNTEENGEEQSVQYWPVNPNEEDMYGSFNVVALPEERA-LPDYIVRKFKLSHSKNPdDSRTITHFQYINWPSTSCPKEATSMIDLVAD
||| .. .|.|||. .|.| |. |||| . .|. || | | | .| |.||..|...... .|. .|||.|||.|..|| ..| ..|..|..
vweqnvtvIvmltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgng.esrtvthfhytgwpdhgvpespaslldfiel
VVRIQRKS-GNGPITVHCSDGLGRTGTFCAMFTVLERLK---AEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFVNTFDN
| ...... ..||. ||||.|.||.|||.|....|..|. |. .|....||.|| |||| | .||.|.. | ||.......
vrkvlkllpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallellkkklt
|
|||||||||
subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 119-360 | 3.3e-85 | 280.3 | In-house | 4-245 (250) | alignment | ||
Range on Protein: 119-360
Range on HMM: 4-245/250.0
AKLPINHGKNRYVNIIPYDHSRVTLKPDG-NPGSDYINASFIGGLNSPKDYIATQGPIPAAFPDFWRMIWEYNVPTIIMVTNLKEDDKIkCHQYWPSFGA
|| | |. |||| .||..|.||| |... . ||||||||. | . | .||||||..|.. |||||..|... ||.|.||||| .| .||||| .|
akkpqnkeknryadiialdssrvvLekekgdkesdyinasflhgyderkafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqywPveka
ANYGSFQVTLKEVETVADYAIRTFQLQSLHGQGPiKEVRQYHFLVWPDHGVPQYATPLLSFQKRVRNHHKG-KPGPMVVHCSAGVGRTGTFITIDTMIMK
.||. .|.|.. |. ||| .|...| . . .. . |||.||.|||| |||..|| | ..|.|. .. . .|..|.|||||||.|.||.||... .
ekyGdvtvsllskeefadytkrklklskakkade.rivrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidavler
IDAEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAIMCR
. | .||.|.... .| | .|.. .|| |....||.|. .
lkkekvvdvfkvikvlrkdrphavesleqyvfvyeiilkaldsv
|
|||||||||
0045098 | (Phosphotyrosine protein) phosphatases II | 110-361 | 1.2e-84 | 279.2 | In-house | 19-276 (278) | alignment | ||
Range on Protein: 110-361
Range on HMM: 19-276/278.0
LEWNFTSYAAKLPINHGKNRYVNIIPYDHSRVTlkpdgnpgsDYINASFIGGLnsPKDYIATQGPIPAAFPDFWRMIWEYNVPTIIMVTNLKEDDKIKCH
| . . . | .. | ||||..|.||||||| ||||||.| | || .|||||| | . |||||.||.....|.|.|.|.|....||.
lgipseitpalylgnldknRykdilpydhsrVk.........dYINAsyidgy..pkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekca
QYWPSFGAANYGSFQVTLKEVETVADYAIRTFQLQSL---HGQGPIKEVRQYHFLVWPDHGVPQYA--TPLLSFQKRVRNHHK-------------GKPG
||||. | .|| |.|||...|.. || .||. .. | . .. .|...|.| ||||||| . ...|.. ...|...| ...|
qywpeggsltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsgg
PMVVHCSAGVGRTGTFITIDTMIMKIdaEGIVDIFNFVRGMRFCRNY-MVQTASQYDFLHHAILEAIMCRD
|..||||||||||||.. ...|. . || ||... |. .| .|.. .||. .|| ||....|| .....
pvlVHCsaGvgRtGtlvaaylmlell..eggvdlleavkelrsqRpglavqnleqyrflyefllelllrgk
|
|||||||||
0040439 | (Phosphotyrosine protein) phosphatases II | 117-358 | 1.3e-84 | 279.0 | In-house | 4-247 (249) | alignment | ||
Range on Protein: 117-358
Range on HMM: 4-247/249.0
YAAKLPINHGKNRYVNIIPYDHSRVTLKP-DGNPGSDYINASFIGGLNSPKDYIATQGPIPAAFPDFWRMIWEYNVPTIIMVTNLKEDDKIKCHQYWPSF
. |.|| |. ||||..|.||||||| |.. .| ..|||||||.| | ......|||||| | ...|||||.||... .|.|.|.|.| ...||.||||.
svallpenkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywplg
GAANYGSFQVTLKEVETVADYAIRTFQLQSLhGQGPIKEVRQYHFLVWPDHGVPQYATPLLSFQKRVRNHHKG--KPGPMVVHCSAGVGRTGTFITIDTM
| .|| |.|||..||. .|| .||..|. | . |. .|...... |||||||.. .||.| ..||.... |.||..||||||||||||||....|
gsleygdftvtllsvevkddytvrtleltnl.ydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylm
IMKIDAEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAIM
.. .. |. ||... |. .| .|...||. .|| ||. |.|| ..
leqlekelgvdleeavkllrsqRpgavqnpeqyrflyeallelll
|
|||||||||
subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 118-359 | 1.3e-84 | 279.1 | In-house | 19-257 (284) | alignment | ||
Range on Protein: 118-359
Range on HMM: 19-257/284.0
AAKLPINHGKNRYVNIIPYDHSRVTLKP-DGNPGSDYINASFIGGLNSPKDYIATQGPIPAAFPDFWRMIWEYNVPTIIMVTnlkeddKIKCHQYWPSFG
| |. | |||...|...|...| |.. .|. .||||||||| | ... ||||||| . . ||||||||||. ||...| | || |||| .
fanldqnkdknrighilafdknvvklerliGeefsdyinasfitGyqrkdkyiatqGPldntladfWrmiweyncstivllt......kdkcsqywplki
AANYGSFQVTLKEVETVADYAIRTFQLQSLHGQGPIKEVRQYHFLVWPDHGVPQYATPLLSFQKRVRNHHK--GKPGPMVVHCSAGVGRTGTFITIDTMI
... |.| .. || ..|..| ..| . |...||.||| |||.|||.|...|. . |.|| .. .. ..||||||||||||..|..|...
vikeerfkvkvdsveeseeyvvrdielsedgkekdirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrtgvyivldvll
MKIDAEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAIMC
... | ||..||||..| || .|| || |.. |.|| .
drmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleehlf
|
|||||||||
0047943 | (Phosphotyrosine protein) phosphatases II | 378-651 | 2.5e-84 | 278.2 | In-house | 4-272 (273) | alignment | ||
Range on Protein: 378-651
Range on HMM: 4-272/273.0
EIAPSSGKTGFQSQFETLESSSPtddDFDCSIAQLSDNLAKSRVKEHLPPNDYRVVLstKNYDSDYICASYVDGYRQRSAFIATQGPMKNTAGDFWRMVW
. ...|.|... .||.| | | ....|.|.| .|. | | | || .. ||.| .. .||||.|||||||.. .|||||||..|| .|||||||
llekllgltllleefelllslkp...lltysvallpenkdknrykdilpydhsrvkl..gdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvw
EMKSMIIIMLTNTEENGEEQSVQYWPVNPNE-EDMYGSFNVVALPEERaLPDYIVRKFKLSHSKNPDdSRTITHFQYINWPSTSCPKEATSMIDLVADVV
| .. .|.|||...|.| |. |||| . .| . .|| | | | || .||.||...|....... |||.|||.| .|| ..| .|..... .|
eqnvrviVmLtelvelgrekcaqYwpleggelsltygkftvtllseet.kddytvrtleltnlgtge.srtvthfhytgwpdhgvppslesllefielvr
RIQRKS-GNGPITVHCSDGLGRTGTFCAMFTVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFV
...... .|||. ||||.|.||||||.|....|..|..|. .||...|| || |||| | .||.|...|.||..
kalealpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyealleyl
|
|||||||||
0040438 | (Phosphotyrosine protein) phosphatases II | 382-657 | 7.6e-84 | 277.0 | In-house | 14-282 (317) | alignment | ||
Range on Protein: 382-657
Range on HMM: 14-282/317.0
SSGKTGFQSQFETLESSSPTdddfDCSIAQLSDNLAKSRVKEHLPPNDYRVVLSTKNY--DSDYICASYVDGYRQRSAFIATQGPMKNTAGDFWRMVWEM
|..|.....||.| | .. ..|.|.| .| | | . || . ||.|| .. |||||.||||||.... .|||||||..|| .||||||||
ksdftalleefedllslkld....tysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPlpntvedFwrmvweq
KSMIIIMLTNTEENGEEQSVQYWPVnpNEEDMYGSFNVVALPEERaLPDYIVRKFKLSHSkNPDDSRTITHFQYINWPSTSCPKEATSMIDLVADVVRIQ
.. .|.|||..||.| |.. |||| .|. || | | | || |.....|....... . ..|||.|||.|..|| ..|. ....|.. | . .
gvtvivmLteleelgrekcaqYwpl..getltygdftvtllseee.lagitlrtlevedl.gdsesrtvthfhytgWpdhgvppspdllldfleavreal
RkSGNGPITVHCSDGLGRTGTFCAMFTVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFVNTFDNY
. ...||. ||||.|.||||||.|....||.|. |. .||...||.|| |||| | .||.|...|.||........
e.dpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleylkrkltl
|
|||||||||
subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 384-655 | 1.4e-83 | 275.5 | In-house | 20-287 (305) | alignment | ||
Range on Protein: 384-655
Range on HMM: 20-287/305.0
GKTGFQSQFETLESSsPTDDDfdcsIAQLSDNLAKSRVKEHLPPND--YRVVLSTKNYDSDYICASYVDGYRQRSAFIATQGPMKNTAGDFWRMVWEMKS
..|.. |...| . .. | . . . | ||.|.|| . .| ... . .. ||||| |||||||... ..|..|||.||| ||||...|.|
sdkgleaqykslyee.eesid....vgkkeankaknrlkeitlldddriiltekeslddsdyinasyvdgykrkkkyivaqgPlkntvadfWrliveekv
MIIIMLTNTEENGEEQSVQYWPVNPNEEDMYGSFNVvALPEERALPDYIVRKFKLSHSKNPDDSRTITHFQYINWPSTSCPKEATSMIDLVADVVRIQRK
|.|||.. |.|... |||| . .|. .|.|.| | .|.. .||| ||.|.| .. ..|||....| .|| |..|||...|. .| . |.|
stivmltklveggkdkCrqYWpesktekkefgefsv.elksektasdyieRklkisiededkesrtvlqyqltdWPdhGvpqfatsllslikrvqkdqkk
SGNGPITVHCSDGLGRTGTFCAMFTVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFVNTFD
. . |..||||.|.||||.|.|. |||||.|.|.||| .|.|| .|.. |. ||| |.| | | ....|
dkgvpllVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkmvqtldqYvflhdaldelitcgd
|
|||||||||
0042113 | (Phosphotyrosine protein) phosphatases II | 119-356 | 3.7e-83 | 274.0 | In-house | 4-242 (245) | alignment | ||
Range on Protein: 119-356
Range on HMM: 4-242/245.0
AKLPINHGKNRYVNIIPYDHSRVTLKPDGNP-GSDYINASFIGGLNSPKDYIATQGPIPAAFPDFWRMIWEYNVPTIIMVTNLKEDDKIKCHQYWPSFGA
|.|| |. ||||..|.||||.|| |.|||. .|||||||...| . .. .|||||| | ..|||||.||... ||.|.|.. |....||.||||. .
allpenkdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywplges
ANYGSFQVTLKEVETVADYAIRTFQLQSlHGQGPIKEVRQYHFLVWPDHGVPQYATPLLSFQKRVRNHHK-GKPGPMVVHCSAGVGRTGTFITIDTMIMK
.|| |.|||...|. .|| .||.... .| .. .||..||.| ||||||| . ||.| ..||.. . ...||..||||||||||||||....|..
ltygdftvtllseehlddytvrtlevtn.lgddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleq
IDAEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEA
...|. |.... |. .| .| .||| ||| ||..|.||
lekelgvsleeavkelrsqRpgavqtpsqyrflyeallel
|
|||||||||
0045450 | (Phosphotyrosine protein) phosphatases II | 371-651 | 2.2e-82 | 272.5 | In-house | 12-304 (307) | alignment | ||
Range on Protein: 371-651
Range on HMM: 12-304/307.0
TKIATLKEIAPSSGKTGFQSQFETLESSSPTDdDFDCSIAQLSDNLAKSRVKEHLPPNDYRVVLSTKNY---DSDYICASYV--------DGYRQRSAFI
.|. |. . . ...||.. .||.| | ... ...|||.| | | | |. || .. ||.||. . ||||| |||| |||.. .||
lkllllvllllldfltgllkefekllsvtvfl.lgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydlkrkfI
ATQGPMKNTAGDFWRMVWEMKSMIIIMLTNTEENGEEQSVQYWPVNpNEEDMYGSFNVVALPEERaLPDYIVRKFKLSHSKNPDDSRTITHFQYINWPST
|||||...| |||||.|| .. .|.|||...|.| |. .|||| . .|| .|| | | | || |..|.||........ . |||.|||.|..|| .
atqgPlpetvedFwrmlweqgvtvivmltelvelgrekcaqywPde.geeltygnftvtllseeh.ldgytvrtlevtdldgtgesrtvthfhytgwpdh
SCPKEATSMIDLVADVVRIQRKS-GNGPITVHCSDGLGRTGTFCAMFTVLERLKAEQV---IDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFV
..|. ...|.. | ...... ..||. ||||.|.||||||.|....|..|..|.. .|....||.|| |||| | .||.|...|.||..
gvppsfeelldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeallell
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 124-355 | 2.4e-82 | 271.2 | Pfam-A | 1-235 (235) | alignment | ||
Range on Protein: 124-355
Range on HMM: 1-235/235.0
NHGKNRYVNIIPYDHSRVTLkpDGNPG-SDYINASFIGGLNSPKDYIATQGPIPAAFPDFWRMIWEYNVPTIIMVTNLKEDDKIKCHQYWP--SFGAANY
|. |||| .|.|||..|| | .|..| ||||||... | ...| .||||||.. . |||||.|...| .|.|.|.|.| .. ||.|||| . . .|
nkkknRykdilpydktrvkl..kgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeeslty
GSFQVTLK-EVE-TVADYAIRTFQLQSLHGQGPIKEVRQYHFLVWPDHGVPQYATPLLSFQKRVRNHHKGKPGPMVVHCSAGVGRTGTFITIDTMIMKID
|...|.|| ... ..|..|...|.. .. .||.|.|. |||||||. ...||.. ..|..... | ||.||||||||||||||...|.......
gdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleqle
AEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILE
||. ||....|. .| .|. |||...|| ||..||||
aeeevdvlqivkelRkqRpgmvqsleqYiflykaile
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 124-355 | 2.4e-82 | 271.2 | In-house | 1-235 (235) | alignment | ||
Range on Protein: 124-355
Range on HMM: 1-235/235.0
NHGKNRYVNIIPYDHSRVTLkpDGNPG-SDYINASFIGGLNSPKDYIATQGPIPAAFPDFWRMIWEYNVPTIIMVTNLKEDDKIKCHQYWP--SFGAANY
|. |||| .|.|||..|| | .|..| ||||||... | ...| .||||||.. . |||||.|...| .|.|.|.|.| .. ||.|||| . . .|
nkkknRykdilpydktrvkl..kgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeeslty
GSFQVTLK-EVE-TVADYAIRTFQLQSLHGQGPIKEVRQYHFLVWPDHGVPQYATPLLSFQKRVRNHHKGKPGPMVVHCSAGVGRTGTFITIDTMIMKID
|...|.|| ... ..|..|...|.. .. .||.|.|. |||||||. ...||.. ..|..... | ||.||||||||||||||...|.......
gdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleqle
AEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILE
||. ||....|. .| .|. |||...|| ||..||||
aeeevdvlqivkelRkqRpgmvqsleqYiflykaile
|
|||||||||
0039614 | (Phosphotyrosine protein) phosphatases II | 374-656 | 2.9e-82 | 271.8 | In-house | 20-294 (297) | alignment | ||
Range on Protein: 374-656
Range on HMM: 20-294/297.0
ATLKEIAPSSGKTGFQSQFETLESSSPtdddfDCSIAQLSDNLAKSRVKEHLPPNDYRVVLSTKN---YDSDYICASYVDGYRQ-RSAFIATQGPMKNTA
. |. . . ..||... .||.| | | |.|||.| | | | |..|| .. ||.|.... |||||.|||||||.. .|||||||...|
dlllllekansktllllefeellslkp.....dysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIatqgPlpetv
GDFWRMVWEMKSMIIIMLTNTEENGEeQSVQYWPVNPNeedMYGSFNVVALPEERaLPDYIVRKFKLSHsknPDDSRTITHFQYINWPSTSCPKEATSMI
.|||||||| .. .|.|||...|.| . .|||| . . .|| | | | .| |..|.||...... . |||.|||||..|| ..| .....
edFwrmvweqgvtvivmLtklvelgr.kcaqywpeegg...tygdftvtllkveh.ldgytvrtlevtn...ngesrtvthfqytgwpdhgvppslelll
DLVADVVRIQRKS-GNGPITVHCSDGLGRTGTFCAMFTVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFVNTFDN
... | ...... ..||. ||||.|.||||||.|....||.|. |. .||...||.|| |||| | .||.|...|.||.......
eflelvrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydallellkrklt
|
|||||||||
subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 383-658 | 3.8e-82 | 270.9 | In-house | 17-287 (318) | alignment | ||
Range on Protein: 383-658
Range on HMM: 17-287/318.0
SGKTGFQSQFETLESSSPTDDDFDCsiaQLSDNLAKSRVKEHLPPNDYRVVLSTK--NYDSDYICASYVDGYRQRSAFIATQGPMKNTAGDFWRMVWEMK
||.. .....| |. |. | .. . | || | |. .. || |... . .|||| |.|.||||.. |.||.|.|. .| |||||||| .
sGelllseeyerlsrseetvtslks...lepvnkaknryanilaydhtrvkLqmlegeegsDyinanyidGyrrkkayiaaqaPlpetieDfWrmvWeqn
SMIIIMLTNTEENGEEQSVQYWPVNpnEEDMYGSFNvVALPEERALPDYIVRKFKLSHsKNPDDSRTITHFQYINWPSTSCPKEATSMIDLVADVVRIQR
|..|.|||..||.| .. .||| . . ||. | | || | ||..|.||... .. ..||.. ..| .|| .. |....|..||| .| ..|.
savivmltqeeergkakvhryWPsk..gsrsygklv.velkeevelsdyvlrefkvtr.teeeesrqvrqyhytsWpdegvpesgaslldlvrqvskaqq
KSGNGPITVHCSDGLGRTGTFCAMFTVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFVNTFDNYD
|||.|||.|||| | ||||.|.|. ..|||.|||...||| |||.|| ||. | ||||||... ||.....| .
ksgagpivvhCsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqtedqyefiydvllealasgdtev
|
|||||||||
subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 381-657 | 1.6e-80 | 265.1 | In-house | 15-289 (290) | alignment | ||
Range on Protein: 381-657
Range on HMM: 15-289/290.0
PSSGKTGFQSQFETLESsspTDDDFDCSIAQLSDNLAKSRVKEHLPPNDYRVVLSTKNYDSD----YICASYVDGYRQRSAFIATQGPMKNTAGDFWRMV
. |..||..||..|.| .. .. .. |.| . | .. ....|.|..| .. . | || |.|..||... ..||||||..||. |||...
hakgnegfrnqfkmlds...gesehtvtvgltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgykekkqyiatqgpvsntlvdFWkli
WEMKSMIIIMLTNTEENGEEQSVQYWPVNPNEEdmYGSFNVVaLPEERALPDYIVRKFKLSHSKNPDDSRTITHFQYINWPSTSCPKEATSMIDLVADVV
|. |. ||.|||| |.|... |||| ..... || |.. | .|..| .|| ||... .... ......|..| ||.|| .. .... ... ..
wqekvtiivmltniieegkvkCqqYWpdsdtka..ygefsik.llneetlneyierklevknknsagakqsvtqyqitnwdstgkvtnpqtillvieemy
RIQRKSGNGPITVHCSDGLGRTGTFCAMFTVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFVNTFDNY
..|||.||..| |||||..||...|||. | ... | |.|||||. .|..|||.|| |. .||..|.. |. ...|..|
ktqrkrgntsivvHCSdtvgrsavfcaaattinkcktegvidvfqvlksqRiqkpgsvqtvqqyqgifqivltyldsfety
|
|||||||||
DSPc_SM00195 | 388-651 | 2.8e-80 | 264.8 | In-house | 2-262 (263) | alignment | |||
Range on Protein: 388-651
Range on HMM: 2-262/263.0
FQSQFETLESSSPTDddfDCSIAQLSDNLAKSRVKEHLPPNDYRVVLSTKN--YDSDYICASYVDGYRQRSAFIATQGPMKNTAGDFWRMVWEMKSMIII
.. .||.||.| ... ... |. . | .| | |..|| .. || |.... .||||.|.|..|.......||||||...| ||||||||.|. ||.
lkeefekleestspk...etteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiiv
MLTNTEENGEEQSVQYWPVNPNEEDMYGSFNVVALPEERALPDYIVRKFKLSHSKNpDDSRTITHFQYINWPSTSCPKEATSMIDLVADVVRIQRKSgNG
|||. ||||.|. .||| . ... .|...| .| ..|.|...|.. .. ...|..|..|| ||| ..|....|...|. | ...| .|
mlteeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegk.eetrkvtqyqyknWpdhgvpdstksvlellravkksksts.sg
PITVHCSDGLGRTGTFCAMFTVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFV
|| ||||.|.||||||... ..|..|..|. .|.|..|| || |||| |. .|| ||..|.||..
pivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi
|
|||||||||
PTPc_SM00194 | 388-651 | 2.8e-80 | 264.8 | In-house | 2-262 (263) | alignment | |||
Range on Protein: 388-651
Range on HMM: 2-262/263.0
FQSQFETLESSSPTDddfDCSIAQLSDNLAKSRVKEHLPPNDYRVVLSTKN--YDSDYICASYVDGYRQRSAFIATQGPMKNTAGDFWRMVWEMKSMIII
.. .||.||.| ... ... |. . | .| | |..|| .. || |.... .||||.|.|..|.......||||||...| ||||||||.|. ||.
lkeefekleestspk...etteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiiv
MLTNTEENGEEQSVQYWPVNPNEEDMYGSFNVVALPEERALPDYIVRKFKLSHSKNpDDSRTITHFQYINWPSTSCPKEATSMIDLVADVVRIQRKSgNG
|||. ||||.|. .||| . ... .|...| .| ..|.|...|.. .. ...|..|..|| ||| ..|....|...|. | ...| .|
mlteeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegk.eetrkvtqyqyknWpdhgvpdstksvlellravkksksts.sg
PITVHCSDGLGRTGTFCAMFTVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFV
|| ||||.|.||||||... ..|..|..|. .|.|..|| || |||| |. .|| ||..|.||..
pivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi
|
|||||||||
subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 374-660 | 3.4e-80 | 264.1 | In-house | 8-287 (287) | alignment | ||
Range on Protein: 374-660
Range on HMM: 8-287/287.0
ATLKEIAPSSGKTGFQSQFETLESSSPTDDDFDCSIAqlSDNLAKSRVKEHLPPNDYRVVLStkNYDSDYICASYVDGYRQRSAFIATQGPMKNTAGDFW
. . . . |..||. || .||. . ..|. .|| |.| | |... |.|..|||.| . . ||| |...|||... |||....|| ||| .||
gefvakghakgnegfknqftvleqvtqredevthnia..sqnkdknRltqilvpdnyrvllk..gehpdyinavfidgykekkafiiaesPmfntarnfW
RMVWEMKSMIIIMLTNTEENGEEQSVQYWPVNPNeeDMYGSFNVVALPEErALPDYIVRKFKLSHSKNPDDSRTITHFQYINWPSTS-CPKEATSMIdLV
..... . .|.||.. .|| ||. |||| . . ..| .|. | || .||.||... .... .| .... .|. ||.|| .. .|... ..
kliddrnvtaivmlcqekendeevcyqyWpeeks..vvlGeyniellnee.vnagyierklevknknkagdkqqvkqyqitnWdstgkvtepqtill.vi
ADVVRIQRKSGNGPITVHCSDGLGRTGTFCAMFTVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFVNTFDNYDNF
. .. |||.||..| |||||. ||...|||. | ... | | |||||. .| |||.|| | ..||.|| .. ||....|. | .|
eemyktqrkrgntsivvhCsdtvGrsamfcaaattinkckteGviDvfqvlksqriqkpgsvqtveqykfindivleyldsfetysdf
|
|||||||||
0043336 | (Phosphotyrosine protein) phosphatases II | 381-651 | 3.6e-80 | 264.7 | In-house | 15-277 (278) | alignment | ||
Range on Protein: 381-651
Range on HMM: 15-277/278.0
PSSGKTGFQSQFETLESSSPtdddFDCSIAQLSDNLAKSRVKEHLPPNDYRVVLSTKNYD--SDYICASYVDGYRQRSAFIATQGPMKNTAGDFWRMVWE
..||... .||.| | . ...|||.| .| | | | || . ||.|| ..| ||||.|||||||.. .|||||||...| .||||||||
llnlktllllefeellsfkl....dtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpetvedFwrmvwe
MKSMIIIMLTNTEENGEEQSVQYWPvnpNEEDMYGSFNVVALPEERaLPDYIVRKFKLSHsKNPDDSRTITHFQYINWPSTSCPKEATSMIDLVADVVRI
.. .|.|||. .|.| ....|||| .. || | | | || |.||.||...... . . |||.||..|..|| ..| ....|.. .| ..
lgvttivmLtelvelgrvkcaqYwp...ggsltygdftvtllkeeh.lddytvrtlevtn.lgdgesrtvthyhylgwpdhgvpeslsllldflkavrea
QRkSGNGPITVHCSDGLGRTGTFCAMFTVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFV
.. . |||. ||||.|.||||||.|....||.|. |. .|....||.|| |||| | .||.|...|.||..
le.dsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyealleyl
|
|||||||||
subfamily_Ptp69D_pd | Subfamily Ptp69D | 83-376 | 6.7e-80 | 263.5 | In-house | 6-305 (307) | alignment | ||
Range on Protein: 83-376
Range on HMM: 6-305/307.0
VSDFIEMMALLQSNNSDRLEEEYPDIE-LEWNFTSYAAKLPINHGKNRYVNIIPYDHSRVTLKP-DGNPGSDYINASFIGGLNSPKDYIATQGPIPAAFP
. | | . . . |..|| .| | . .. ... | |||| .|...|. || ||. |. ||||||||| | . |..|| |.|. |
iddleealksrkrdtdfglakeyekLeareidkstkvsekkenalknRyedikafDktRvkLkkingkedsdYinasfikgykekkkfiaaqdPveatig
DFWRMIWEYNVPTIIMVTNLKEDDKIKCHQYWPSFGAANYGSFQVTLKEVETVADYAIRTFQLQSLHGQG----PIKEVRQYHFLVWPDHGVPQYATPLL
||||||.| .| .|.|..||.| .. ||..||| .||. |.| . |. ||.||.... . .. ..| |||.. |.| ||. |. ||
DfWRmiaeqevtlivmlsnlteknrkkcakYWpiedevqygdilvklvseekhsdyiiReldvskkkeesgevedsrkvvqyhytgWkDskvPevargll
SFQKRVRNHHKGKPGPMVVHCSAGVGRTGTFITIDTMIMKIDAEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAIMCRDTTIPAVHMATKIATL
. ..||...| . .|.||||||||||.|.|...| .. .. || ||||..|...| || .|| || ||..|.|. .. || . ... .| .|
klieqvrelyklnrsPivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnllvqsleqYvflyralldyssygdtdedvddledaierl
|
|||||||||
0037934 | (Phosphotyrosine protein) phosphatases II | 117-356 | 9.1e-80 | 263.0 | In-house | 3-241 (243) | alignment | ||
Range on Protein: 117-356
Range on HMM: 3-241/243.0
YAAKLPINHGKNRYVNIIPYDHSRVTLkpdgnPGSDYINASFIGGLnsPKdYIATQGPIPAAFPD----FWRMIWEYNVPTIIMVTNLKEDDKIKCHQYW
. |.|| |. |||| .|.||||||| | .|||||||..| .. |. .|||||| | . | ||||.||... .|.|.|.|.| ...||.|||
siallpenlsknrysdilpydhsrvkl.....egsdyinanliyvt..pr.liatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqyw
PsfGAANYGSFQVTLKEVETVADYAIRTFQLQSLHGQGPIKEVRQYHFLVWPDHGVPQYATPLLSFQKRVRNH--------HKGKPGPMVVHCSAGVGRT
| | .|| |.|||...|. .|| .||..|. | ... ..|..||.| |||||||. ..||.| . ||.. . . ||..||||||||||
p..gevtygdftvtllseehlddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRt
GTFITIDTMIMKIdaeGiVDIFNFVRGMRFCRNY-MVQTASQYDFLHHAILEA
||.|....|.... | ||... |. .| .|.. .||| ||| ||..|.||
Gtliaaylmllll...g.vdleeavkllreqRpgkavqtpsqyrflyeallel
|
|||||||||
subfamily_PTPN12_pd | Subfamily PTPN12 | 111-357 | 5.1e-79 | 260.2 | In-house | 27-277 (290) | alignment | ||
Range on Protein: 111-357
Range on HMM: 27-277/290.0
EWNFTSYAAKLPINHGKNRYVNIIPYDHSRVTLKP-DGNPGSDYINASFIGGLNSPKDYIATQGPIPAAFPDFWRMIWEYNVPTIIMVTNLKEDDKIKCH
| ... |.. . | |||| .|.|||.|||.|. ....|||||||.|| | .... |||.|||.|.. ||||||||.|| ..|. .. | .|.||.
ekvysteagekeenvkknrykDilPydksrvelskieeeegsdYinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCe
QYWPSFGAA--NYGSFQVTLKEVETVA-DYAIRTFQLQSlhgQGPIKEVRQYHFLVWPDHGVPQYATPLLSFQKRVRNHHKGKPGPMVVHCSAGVGRTGT
.|||. | ..|.|.|||.| ..| |. |||.... |. ..|.|.|. |||||||. |..||.. . ||.... . |.|||||||||||||
rYWpeegeeelefgefevtleeekavdddflirtLkvea...qkesrkvyqfhYtaWPDhgvPssaksllelielvrelqesedaPlvvhCsaGvGrtGt
FITIDTMIMKIDAEGI---VDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAI
|.|| . . . || | .|.|. |. .| |. .||| || ....|..| .
iiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelv
|
|||||||||
subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 79-369 | 8.6e-79 | 259.7 | In-house | 8-296 (297) | alignment | ||
Range on Protein: 79-369
Range on HMM: 8-296/297.0
PPLNVSDFiemMALLQSNNSDR-LEEEYPDIELEWNFTSYAAKLPINHGKNRYVNIIPYDHSRVTLKPDGN-PGSDYINASFIGGLNSpkDYIATQGPIP
|. .||| .|.| | . .||. .. ... |. .| |.|| ||.||| |||.|. .. | |||.||||. | . .|.|| | .
rpiplsdf...atlvqknrhtdvfseeflclpeaniqpqtvaekkvnfeksRYkniLPydssRvkLaivnddpdsDyvnasfvkgnkh..rlittqmPmk
AAFPDFWRMIWEYNVPTIIMVTNLKEDDKiKCHQYWPSFGAANYGSFQVTLKEVETVADYAIRTFQLQSLHGQgPIKEVRQYHFLVWPDHGVPQ--YATP
|. |||.|.....| ||.|.....| || || .||. | ...|. |.|. |. . |..... . . . |.||.|. |||. |.. |.
atvadfWamvldeqvstivmlnddnerdk.kcaryWsdkgvttfGdvsvvllsvsereGfikrelevtkgkak.arrvvkqyqfveWPdkaverkdsass
LLSFQKRVRNHHKGKPG-PMVVHCSAGVGRTGTFITIDTMIMKIDAEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAIMCRDTTIPAVHM
|| . . ||...... |..|||.||||||| ..||| .. .. | ||||..|. .| | |.||| || |.. |.|||... || |.| ..
llklisevrkdfsqnaegPllvhclaGvGrtgvlltidsvvaeakrekevdifglvkklrqerpylvqtkeqykfvyvavleallsedtriqasyf
|
|||||||||
subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 408-658 | 1.1e-78 | 258.9 | In-house | 2-249 (250) | alignment | ||
Range on Protein: 408-658
Range on HMM: 2-249/250.0
SIAQLSDNLAKSRVKEHLPPNDYRVVLSTKN--YDSDYICASYVDGYRQRSAFIATQGPMKNTAGDFWRMVWEMKSMIIIMLTNTEENGEEqSVQYWPVN
|.|. .|. | | . .. . |||| ... .|||| ||...||..|.||||||||...| ||||||.| || |.|||| .|.... |||||.
svakkpqnkeknryadiialdssrvvLekekgdkesdyinasflhgyderkafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqywPve
PNEedMYGSFNVVALPEErALPDYIVRKFKLSHSKNpDDSRTITHFQYINWPSTSCPKEATSMIDLVADVVRIQRKSGNGPITVHCSDGLGRTGTFCAMF
| ||. | | .| ||..||.|||. |. |.|.. ......|| . |..||....|. .| . |...||.|. |.|| | ||.|.|.|.
kae..kyGdvtvsllske.efadytkrklklskakk.aderivrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaid
TVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFVNTFDNYD
.|||||| |.|.||| .|.||..||. |. .|| |.....|........|
avlerlkkekvvdvfkvikvlrkdrphavesleqyvfvyeiilkaldsvedya
|
|||||||||
subfamily_PTPN6_pd | Subfamily PTPN6 | 101-357 | 9.1e-78 | 256.3 | In-house | 28-297 (306) | alignment | ||
Range on Protein: 101-357
Range on HMM: 28-297/306.0
LEEEYPDI---ELEWNFTSYAAKLPINHGKNRYVNIIPYDHSRVTLKPDGNPGSDYINASFIG--GLNSPKDYIATQGPIPAAFPDFWRMIWEYNVPTII
.|||. .. | . .. .. | |. |||| ||.|.||.||.|| .. ||||||||..| .| | |||||| ... .|||||.|. | |.
feeefeelqqeeakkllsrkegakpenkeknryknilPfDhtrvilkepsvpgsdyinanyikkevkgsdksyiatqgclettvsdFWrmvwqensrviv
MVTNLKEDDKIKCHQYWPSFGA-ANYGSFQVTLKEVETVADYAIRTFQLQSLHGQGPIKEVRQYHFLVWPDHGVPQYATPLLSFQKRVRNHHKGKP----
|.|. | | || .|||. . .||. .|| . .. ||| .|..... . .. .||.|||| .|||||||. .|.| . |.....
mttkevErgkekCarYWPdeeekeeyGkisvtnvseksladYilRelsvskkkkkkeerevfqyhfksWPdhgvpkdpgavLdfledvnrkqeeleeaea
GPMVVHCSAGVGRTGTFITIDTMIMKIDAEGI---VDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAI
||.|||||||.||||||| ||... .| .|. .|| ..|. .| |. .|||..|| |...|| . |
gpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqteqqykfvykaikkyi
|
|||||||||
subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 123-363 | 3.7e-77 | 254.1 | In-house | 46-284 (287) | alignment | ||
Range on Protein: 123-363
Range on HMM: 46-284/287.0
INHGKNRYVNIIPYDHSRVTLKpdgNPGSDYINASFIGGLNSPKDYIATQGPIPAAFPDFWRMIWEYNVPTIIMVTNLKEDDKIKCHQYWPSFGAANYGS
|. |||. .|...| || || . |||||.|| | .. | .|....|. . .||..|.. ||..|.|....||.|. .|.||||. . .|
qnkdknRltqilvpdnyrvllk...gehpdyinavfidgykekkafiiaesPmfntarnfWkliddrnvtaivmlcqekendeevcyqyWpeeksvvlGe
FQVTLKEVETVADYAIRTFQLQSLHGQGPIKEVRQYHFLVWPDHG-VPQYATPLLSFQKRVRNHHKGKPGPMVVHCSAGVGRTGTFITIDTMIMKIDAEG
....| . |. |.| .|..... . .|. ..|.||.. |...| |....| || .........| ...|||||..|||...|. ..| | | . ||
yniellneevnagyierklevknknkagdkqqvkqyqitnWdstgkvtepqtillvieemyktqrkrgntsivvhCsdtvGrsamfcaaattinkckteG
IVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAIMCRDTT
..|.|. .. .| . .|||..|| |. ...|| . . .|
viDvfqvlksqriqkpgsvqtveqykfindivleyldsfety
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 415-649 | 8.9e-77 | 253.0 | Pfam-A | 1-235 (235) | alignment | ||
Range on Protein: 415-649
Range on HMM: 1-235/235.0
NLAKSRVKEHLPPNDYRVVLSTKNYDSDYICASYVDGYRQRSAFIATQGPMKNTAGDFWRMVWEMKSMIIIMLTNTEENGEEQSVQYWPVNPNEEDMYGS
|. | | |. || .. || |. .. .|||| |.||.||.. ..|||||||.|.| .|||||||. |. .|.|||. ||.|.|. |||| . .|. .||.
nkkknRykdilpydktrvklkgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesltygd
FNVVAL-PEERALPDYIVRKFKLSHSKNPDDSRTITHFQYINWPSTSCPKEATSMIDLVADVVRIQrKSGNGPITVHCSDGLGRTGTFCAMFTVLERLKA
..| |... .|..||..|...|.....|......| ||| ..|....|..||. .| . . .. .||..||||.| ||||||.|. ..||.|.|
ikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkveksk.eaksgpvvVhCsaGvgRtgtfvaldilleqlea
EQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALE
|. .||...||.|| |||| |....||.|..|| ||
eeevdvlqivkelRkqRpgmvqsleqYiflykaile
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 415-649 | 8.9e-77 | 253.0 | In-house | 1-235 (235) | alignment | ||
Range on Protein: 415-649
Range on HMM: 1-235/235.0
NLAKSRVKEHLPPNDYRVVLSTKNYDSDYICASYVDGYRQRSAFIATQGPMKNTAGDFWRMVWEMKSMIIIMLTNTEENGEEQSVQYWPVNPNEEDMYGS
|. | | |. || .. || |. .. .|||| |.||.||.. ..|||||||.|.| .|||||||. |. .|.|||. ||.|.|. |||| . .|. .||.
nkkknRykdilpydktrvklkgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesltygd
FNVVAL-PEERALPDYIVRKFKLSHSKNPDDSRTITHFQYINWPSTSCPKEATSMIDLVADVVRIQrKSGNGPITVHCSDGLGRTGTFCAMFTVLERLKA
..| |... .|..||..|...|.....|......| ||| ..|....|..||. .| . . .. .||..||||.| ||||||.|. ..||.|.|
ikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkveksk.eaksgpvvVhCsaGvgRtgtfvaldilleqlea
EQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALE
|. .||...||.|| |||| |....||.|..|| ||
eeevdvlqivkelRkqRpgmvqsleqYiflykaile
|
|||||||||
subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 82-358 | 9.2e-77 | 252.8 | In-house | 3-284 (290) | alignment | ||
Range on Protein: 82-358
Range on HMM: 3-284/290.0
NVSDFIEMMALLQSNNSDRLEEEYPDIEL-EWNFTSYAAKLPINHGKNRYVNIIPYDHSRVTLKPDGNP---GSDYINASFIGGLNSPKDYIATQGPIPA
.|..| |..| .... .. .... .. | ..| . . . |. .||. ||..|| |.||.| .. .||||..| | . |.|||||||..
pvdkfgefvanghakgnegfrnqfkmldsgesehtvtvgltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgykekkqyiatqgpvsn
AFPDFWRMIWEYNVPTIIMVTNLKEDDKIKCHQYWPSFGAANYGSFQVTLKEVETVADYAIRTFQLQSLHGQGPIKEVRQYHFLVWPDHG-VPQYATPLL
|||..||. .|. |.|.|| .|..| ||.||||. ....|| |...| . ||. .| .|...... . .|. ..| ||.. |...| |....| ||
tlvdFWkliwqekvtiivmltniieegkvkCqqYWpdsdtkaygefsikllneetlneyierklevknknsagakqsvtqyqitnwdstgkvtnpqtill
SFQKRVRNHHKGKPGPMVVHCSAGVGRTGTFITIDTMIMKIDAEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAIM
..........| ...|||||..|||...|....| | | || .|.|. .. .| .. .|||. || .... .|...
vieemyktqrkrgntsivvHCSdtvgrsavfcaaattinkcktegvidvfqvlksqRiqkpgsvqtvqqyqgifqivltyld
|
|||||||||
subfamily_Ptp69D_pd | Subfamily Ptp69D | 382-653 | 9.7e-77 | 253.1 | In-house | 16-288 (307) | alignment | ||
Range on Protein: 382-653
Range on HMM: 16-288/307.0
SSGKT--GFQSQFETLESSsptDDDFDCSIAQLSDNLAKSRVKEHLPPNDYRVVLSTKN--YDSDYICASYVDGYRQRSAFIATQGPMKNTAGDFWRMVW
. ..| |.. .|.||.. | ...... .|. | | .. . ...||.|.. | ||||| ||.. ||... ||| |.|. .|.||||||..
rkrdtdfglakeyekLear...eidkstkvsekkenalknRyedikafDktRvkLkkingkedsdYinasfikgykekkkfiaaqdPveatigDfWRmia
EMKSMIIIMLTNTEENGEEQSVQYWPVNpnEEDMYGSFNVVALpEERALPDYIVRKFKLSHSK----NPDDSRTITHFQYINWPSTSCPKEATSMIDLVA
| .. .|.||.| .| ... .|||.. .| ||. .| .|. .||| |....|. | . .||| .. ..| .|. . |. |.....|.
eqevtlivmlsnlteknrkkcakYWpie..devqygdilvklv.seekhsdyiiReldvskkkeesgevedsrkvvqyhytgWkDskvPevargllklie
DVVRIQRKSgNGPITVHCSDGLGRTGTFCAMFTVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFVNT
| ..... ..||.|||| | ||.|.| |. .|..||||. .|.| ||| || ||. .|. ..||.|...| |.. .
qvrelykln.rsPivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnllvqsleqYvflyralldyssy
|
|||||||||
subfamily_PTPRA_pd | Subfamily PTPRA | 404-651 | 1.5e-76 | 252.4 | In-house | 47-295 (330) | alignment | ||
Range on Protein: 404-651
Range on HMM: 47-295/330.0
DFDCSIAQLSDNLAKSRVKEHLPPNDYRVVLSTKN--YDSDYICASYVDGYRQRSAFIATQGPMKNTAGDFWRMVWEMKSMIIIMLTNTEENGEEQSVQY
. . .|. .| |.|| . || . ||.||.|. .|||| ||..|||... |||.||| ..| |||||.|| ||. |.|||. .| ||. ||
qatlelaskeenkeknrvvnilPydfsrvilsvkeGveesdyinasfidGykekdkfiaaqGPkeetvedfwrmiweqksativmltelkerkeekcaqy
WPVNPNeeDMYGSFNVvALPEERALPDYIVRKFKLS---HSKNPDDSRTITHFQYINWPSTSCPKEATSMIDLVADVVRIQRKSGNgPITVHCSDGLGRT
|| . || .| .. .| | || |||| . .... ..|| .. | . || | |. |..|.. | .....|.. ||.|||| | |||
wPdeGl..vtyGnirv.evedetvlvdytvrkflvqqlpdatrekksrlvrqfhftswPdvGvPfepiGmlkllkkvkklnqqsag.pivvhcsaGvGrt
GTFCAMFTVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFV
|||... .||||.|||...||| .|| || ||| |. |||||.|. ||.
Gtfivldavlervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvlleyy
|
|||||||||
subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 118-356 | 5.2e-76 | 249.9 | In-house | 1-239 (239) | alignment | ||
Range on Protein: 118-356
Range on HMM: 1-239/239.0
AAKLPINHGKNRYVNIIPYDHSRVTLKP-DGNPGSDYINASFIGGLN-SPKDYIATQGPIPAAFPDFWRMIWEYNVPTIIMVTNLKEDDKIKCHQYWPSf
||| .|. |||| ||. |||||| |. .| |||||||.. . ||| |||||| . .. |||||.|. |.|.| | | | |||||||
aakkrvnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpd.
GAANYGSFQVTLKEVETVADYAIRTFQLqSLHGQGPIKEVRQYHFLVWPDHGVPQYATPLLSFQKRVRNHHKGKPGPMVVHCSAGVGRTGTFITIDTMIM
...| ..|||.. | .||| |||| . | || . | |||| ||||.||||||| .| ..... . | |.||||||||||.|. ||.|.
stskycnlrvtlrktevfadyiirtfvm.sqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlr
KIDAEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEA
. . |||||.|. .| | .||||. || |.| |.|||
qakkqktvdifnyvkairedrphmvqtseqyvfihlavlea
|
|||||||||
subfamily_PTPN9_pd | Subfamily PTPN9 | 88-356 | 1.2e-75 | 249.3 | In-house | 5-289 (297) | alignment | ||
Range on Protein: 88-356
Range on HMM: 5-289/297.0
EMMALLQSNNSDRLEEEYPDIELEW-NFTSYAAKLPINHGKNRYVNIIPYDHSRVTLKP-DGNPGSDYINASFIGGLNSPKDYIATQGPIPAAFPDFWRM
|..| ..... | .|| .| | . | .|.||. | |||| ... ||..||.|. |... ||||||.|. | . .| .||||||.. .. |||||
elvayvkekgkrGlskeyaeirnepveGtflasklranleknrytdvlcydetrvvlakvdedeasdyinanfvdGykqkkafiatqGplkktvsdfWrm
IWEYNVPTIIMVTNLKEDDKIKCHQYWP--SFGAANYGSFQVTLKEVETVADYAIRTFQLQSLHgQGPIKEVRQYHFLVWPDHGVPQYATPLLSFQKRVR
.|| .| .|.|.| . | ..|| |||| . .|..|...|. |||. || .|..... . .. ...| . || |||.|||. |. || . . ||
vWeqevlvivmttrvvergrlkcgqyWpleeessaefgdlsvsnveveeeedykvrvleiknvk.teesrkvthfqflsWPdyGvPssaaslldvlekvr
NH-----------HKGKP--GPMVVHCSAGVGRTGTFITIDTMIMKIDAEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEA
.. .||.| |.|||||||.||||||||.| . ... .| ||... |. .| | ...|| || | . |.||
ekqalavkelgdewkghpsgPPivvhcsaGiGrtGtfitldiclsrleevgtvdvvetvkllrtqrafsiqtpeqyefcylavley
|
|||||||||
subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 118-355 | 1.6e-75 | 248.4 | In-house | 2-239 (239) | alignment | ||
Range on Protein: 118-355
Range on HMM: 2-239/239.0
AAKLPINHGKNRYVNIIPYDHSRVTLKP-DGNPGSDYINASFIGGLN-SPKDYIATQGPIPAAFPDFWRMIWEYNVPTIIMVTNLKEDDKIKCHQYWPSf
||| .|. |||| ||. |||||| |. .| |||||||.. . ||| |||||| . .. |||||.|. |.|.| | | | |||||||
aakkrvnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpd.
GAANYGSFQVTLKEVETVADYAIRTFQLqSLHGQGPIKEVRQYHFLVWPDHGVPQYATPLLSFQKRVRNHHKGKPGPMVVHCSAGVGRTGTFITIDTMIM
...| ..|||.. | .||| |||| . | || . | |||| ||||.||||||| .| ..... . | |.||||||||||.|. ||.|.
stskycnlrvtlrktevfadyiirtfvm.sqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlr
KIDAEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILE
. . |||||.|. .| | .||||. || |.| |.||
qakkqktvdifnyvkairedrphmvqtseqyvfihlavle
|
|||||||||
subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 124-355 | 4.6e-74 | 243.6 | In-house | 3-237 (237) | alignment | ||
Range on Protein: 124-355
Range on HMM: 3-237/237.0
NHGKNRYVNIIPYDHSRVTLKPDGNpGSDYINASFIGGLN-SPKDYIATQGPIPAAFPDFWRMIWEYNVPTIIMVTNLKEDDKIKCHQYWPSFG-AANYG
|. |||| ||. |||||| || |. |||||||... |.. .|| |||.|||. .. |||.|.|. . |.|.| | | ...|||.|||| | ||
nkiknrygnivaydhsrvvlkgags.gsdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpstdqpaayg
SFQVTLKEVETVADYAIRTFQLQSLHGQGPIKEVRQYHFLVWPDHGVPQYATPLLSFQKRVRN--HHKGKPGPMVVHCSAGVGRTGTFITIDTMIMKIDA
. |.|| | .||..|.. |. . . .. . ||.| .|||.||||... || |.|.. | .| . || ..|||||||||| |. ||.|. .
vltvslkkkeefsdytvrslllskrltlkevrlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlrqake
EGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILE
. .|||.|.| . | |..|| || |.|..|||
kkvvdiynyvysieedrpyiiqtkdqyvfihqtile
|
|||||||||
0040439 | (Phosphotyrosine protein) phosphatases II | 406-651 | 1.1e-73 | 243.2 | In-house | 2-246 (249) | alignment | ||
Range on Protein: 406-651
Range on HMM: 2-246/249.0
DCSIAQLSDNLAKSRVKEHLPPNDYRVVLSTKN--YDSDYICASYVDGYRQRSAFIATQGPMKNTAGDFWRMVWEMKSMIIIMLTNTEENGEEQSVQYWP
..|.|.| |. | | . .||.. ||.|| . ..||||.|||.|||.. .|||||||...| .|||||.|| .. .|.|||...|.| |. ||||
eysvallpenkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywp
VnpNEEDMYGSFNVVALPEERaLPDYIVRKFKLSHSkNPDDSRTITHFQYINWPSTSCPKEATSMIDLVADVVRIQRKS-GNGPITVHCSDGLGRTGTFC
... || | | | .| ..||.||...|... ..|||..|.||..|| ...|. ...|.. | .... .||. ||||.|.||||||.
l..ggsleygdftvtllsvev.kddytvrtleltnl.ydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfi
AMFTVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFV
|....||.|. |. .|....||.|| |||| | .||.|...|.||..
aaylmleqlekelgvdleeavkllrsqRpgavqnpeqyrflyeallell
|
|||||||||
subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 111-393 | 5.1e-73 | 241.0 | In-house | 35-324 (325) | alignment | ||
Range on Protein: 111-393
Range on HMM: 35-324/325.0
EWNFTSYAAKLPINHGKNRYVNIIPYDHSRVTLKPDG-NPGSDYINASFIGGLNSPKDYIATQGPIPAAFPDFWRMIWEYNvPTIIMVTNLKEDDKIKCH
. . .| .| | |||. |....|.||| |. . .| |||||||.. . ..|.| | .|. |.||.. ... ....|.| . .| .|
ddgiakkvamkpenkaknrfknvvaldksrvvletkkddpssdyinasylrddkkkdvflaaqaPltatindlWrlvldWr.csvvvvlneldlgkdrca
QYWPSF--GAANYGSFQVTLKEVETVADYAIRTFQLQSLHGqGPIKEVRQYHFLVWPDHGVPQYATPLLSFQKRVRNHHKG------KPGPMVVHCSAGV
.||| . ..|...| |. .|...|| | .... .. | . |.|... |.| ||... . |.|. . | . .. .|..|||||||
vywpkemgksktfGglevklrtieeisdyvhrvldvkqvkk.GetrsvkqfqlqswddmGvqkrpatlisilqlvkavservtantkastpilvhcsaGv
GRTGTFITIDTMIMKIDAEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAIMCRDTTIPAVHMATKIATLKEIAPSSGKTGFQSQFE
||||.||.. ... |. | ||||.||. .| | ||.|. || ....|. ||.|. .| .| . .|...|.| | . | . .||
GrtGvfislysalakvieesrvdifgfvkklrkdrpsmvetvdqyiliyealveaymsgntdvpvssfeaklsslqernpltqklniekefe
|
|||||||||
subfamily_PTPRK_pd | Subfamily PTPRK | 383-649 | 7.2e-73 | 240.2 | In-house | 19-275 (314) | alignment | ||
Range on Protein: 383-649
Range on HMM: 19-275/314.0
SGKTGFQSQFETLESSsptdddfdCSIAQLSDNLAKSRVKEHLPPNDYRVVLSTKNYD--SDYICASYVDGYRQRSAFIATQGPMKNTAGDFWRMVWEMK
. ||. ..|.| |. .| .|.|... |... ||.| | . | |||| |...|.|.. .|||.||||...| ||||.|.. .
aegygfkeeyeslfeg........wdaakkdenreknrsgdilaydrsrvflitidgdpssdyinaalidsykrpaafivtqgPlqetvkdfWrlvyden
SMIIIMLTNTEENGEEQSVQYWPvnpNEEDMYGSFNVVALpEERALPDYIVRKFKLSH-SKNPDDSRTITHFQYINWPSTSCPKEATSMIDLVADVVRIQ
. |.|||. |.| . ..||| .. ..|| ..| . | .| ...|| |.... ... .. |.. .||...||. |..||....||. | |
casivmltelvevgrvkClkyWP...edtevygdikvelv.etellaelvvrifrveklargqeeirevrqfqflgWpdhdvPvsatgllklvrrvkksq
RKsGNGPITVHCSDGLGRTGTFCAMFTVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALE
. ..|.| |||| | ||||||.|. .||. .. |.|.||| .||||| ... .|. .|| ||. ..||
ee.eaGrivvhCsaGaGrtGtfiaidivldmieregvvdvfnavktlrsrkvnmveteeqykfiydvile
|
|||||||||
subfamily_PTPRG_pd | Subfamily PTPRG | 382-654 | 8.3e-73 | 240.5 | In-house | 15-290 (563) | alignment | ||
Range on Protein: 382-654
Range on HMM: 15-290/563.0
SSGKTGFQSQFETLESSSpTDDDFDCSIAQLSDNLAKSRVKEHLPPNDYRVVLSTKN-YD--SDYICASYVDGYRQRSAFIATQGPMKNTAGDFWRMVWE
..|..||. .|| |.| . ...|.|.. .| .| | | . .. . || || . ||| |.|.|||.. ||||||||.|.|. |||||.||
adgdigfseefealqset.iskdldaehsqkpenkrKnRylnivaydrsRvklsplpgkkkklDYinAnyidGyqkskafiatqgplkdtfddFWrmiWe
MKSMIIIMLTNTEENGEEQSVQYWPVnpNEEDMYGSFNVVaLPEERALPDYIVRKFKLSH-----SKNPDDSRTITHFQYINWPSTSCPKEATSMIDLVA
.. ||.|.|| .|.| .. .||| .| ||...| | || | | ||.... . |. |. .......| .|| .. |. .. . |
qnvaiivmitnlvergrrkcdvYWPk..desetygalqvt.lieeevlalytvrtlviknlklkkkkqcdteklvrqyhytkWPdhgvPehslpvLifvk
DVVRIqRKSGNGPITVHCSDGLGRTGTFCAMFTVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFVNTF
. .|. |||.|||| | |||||.... |.|.....|....|| ..|..| ||. |....|| |.|.| || ...
kssaa.nkaeaGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvqteEqYiflhdalleaiask
|
|||||||||
0042113 | (Phosphotyrosine protein) phosphatases II | 407-651 | 3.7e-72 | 238.0 | In-house | 1-243 (245) | alignment | ||
Range on Protein: 407-651
Range on HMM: 1-243/245.0
CSIAQLSDNLAKSRVKEHLPPNDYRVVLSTKNYD--SDYICASYVDGYRQRSAFIATQGPMKNTAGDFWRMVWEMKSMIIIMLTNTEENGEEQSVQYWPV
.|.|.| | | | .. || .. ||.|| ..| |||| ||||||||. |||||||...| .|||||.|| .. .|.|||..||.| ... ||||
ysvallpenkdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywpl
npNEEDMYGSFNVVALPEERaLPDYIVRKFKLSHsKNPDDSRTITHFQYINWPSTSCPKEATSMIDLVADVVRIQRKSGNGPITVHCSDGLGRTGTFCAM
.|. || | | | || |.||.||...... . | ||...|..|..|| ..| ...|.. | .......|||. ||||.|.||||||.|.
..gesltygdftvtllseeh.lddytvrtlevtn.lgddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaa
FTVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFV
...||.|..|. ......|| || |||| | .||.|...|.||..
ylmleqlekelgvsleeavkelrsqRpgavqtpsqyrflyeallell
|
|||||||||
subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 379-651 | 4.8e-72 | 237.4 | In-house | 14-279 (288) | alignment | ||
Range on Protein: 379-651
Range on HMM: 14-279/288.0
IAPSSGKTGFQSQFETLessSPTDDDFDCSIAQLSDNLAKSRVKEHLPPNDYRVVLST--KNYDSDYICASYVDGYRQRSAFIATQGPMKNTAGDFWRMV
.. ...|||......| .. . . . ....|. | | | .. || . || | .. ..||| |||.||.... ..||||||. .| .|||..|
kksarnrtgfseeynsL...aalektksvtagrlavnakknRyrnilpyDekrvklkkleeeagaDYinasyidgekkkkkyiatqgPladtvndfWelv
WEMKSMIIIMLTNTEENGEEQSVQYWPVNpNEEDMYGSFNVVaLPEERALPDYIVRKFKLShskNPDDSRTITHFQYINWPSTSCPKEATSMIDLVAdVV
.| |. |.|||. |.|... .||| . ... |||..|. | |.. | |...||. | . ..||..|| || .. |. .. ...|. |
yenktstivmltelveggktkCeeYWPda.dkpknyGsvtvt.lveskeledfvlrkllle...kkkteleitqyqylaWpdhgvPeskapllellr.qv
RIQRKSGNGPITVHCSDGLGRTGTFCAMFTVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFV
.. .. |||.||||.|.|||||| |. ........|..|||..||. || ||. .|. |||||... |. .
kvanqadtgpiivhCsaGvGrtgtFialdalidaveeedyiDvagtvaklRkqRallvqtlkqYefiyevllsli
|
|||||||||
subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 97-355 | 1.2e-71 | 236.0 | In-house | 3-266 (274) | alignment | ||
Range on Protein: 97-355
Range on HMM: 3-266/274.0
NSDRLEEEYPDIELewNFTSYAAKLPINHGKNRYVNIIPYDHSRVTLKPDG--NPGSDYINASFIGGLN-SPKDYIATQGPIPAAFPDFWRMIWEYNVPT
.. ||.|. .. | ||. ... .. |||| .|.| ..|||.|... .. |.|||| .| | . | |.|||||.| . ||||||.. .|.
sfkdlekeflelPl..nfdqeeldvfgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqv
IIMVTNLKEDDKIKCHQYWPSFGAA----NYGSFQVTLKEVETVADYAIRTFQLQSLHGqgpIKEVRQYHFLVWPDHGVPQYATPLLSFQKRVRN---HH
|.|.|.||| .. ||..|.| . .|| .... ... . || .|.. |..|. ..| | . |||| .|. |..||.. . |.. ..
ivmltklkeaneqkCavyfPdaedyeiserygdveikvekiverndysvrklvlkyler...ersvkhywytdWPdhksPddantlldlvleveesreee
KGKPGPMVVHCSAGVGRTGTFITIDTMIMKIDAEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILE
. | .|.|||||||.|||| ||.|. . ....|..||... | .| | ||||..||...|.|. .
naklapvvvhCsaGiGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralcl
|
|||||||||
subfamily_PTPN6_pd | Subfamily PTPN6 | 366-654 | 1.2e-71 | 236.2 | In-house | 6-300 (306) | alignment | ||
Range on Protein: 366-654
Range on HMM: 6-300/306.0
AVHMATKIATLKEIAPSSGKTGFQSQFETLESSSpTDDDFDCSIAQLSDNLAKSRVKEHLPPNDYRVVL-STKNYDSDYICASYVDGYRQ--RSAFIATQ
| .. .. |.. | .|.||. .||.|. . . . .. . .. .| | | | || .. ||.| . . ..|||| |.|... . . ..||||
akeieqrvselekeeeslekagfeeefeelqqee.akkllsrkegakpenkeknryknilPfDhtrvilkepsvpgsdyinanyikkevkgsdksyiatq
GPMKNTAGDFWRMVWEMKSMIIIMLTNTEENGEEQSVQYWPVNPNEEDmYGSFNVVALPEeRALPDYIVRKFKLSHSKNPDDSRTITHFQYINWPSTSCP
| ...| |||||||. .| .|.|.|. | |.|. ..||| . ..|. ||. .| . | ..| |||.|....|. |. ...|.. .... .|| ..|
gclettvsdFWrmvwqensrvivmttkevErgkekCarYWPdeeekee.yGkisvtnvse.ksladYilRelsvskkkkkkeerevfqyhfksWPdhgvp
KEATSMIDLVADVVRIQRKSG---NGPITVHCSDGLGRTGTFCAMFTVLERLK---AEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFVNTF
|. ..|.. || | |... .||| ||||.|.|||||| . ..|. .. . ||. ..||..| || |.|. .|| |..|| ....|
kdpgavLdfledvnrkqeeleeaeagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqteqqykfvykaikkyietk
|
|||||||||
subfamily_PTPN3_pd | Subfamily PTPN3 | 115-358 | 4.4e-71 | 234.1 | In-house | 32-276 (280) | alignment | ||
Range on Protein: 115-358
Range on HMM: 32-276/280.0
TSYAAKLPINHGKNRYVNIIPYDHSRVTLKPDGNpgsDYINASFIG----GLNSPKDYIATQGPIPAAFPDFWRMIWEYNVPTIIMVTNLKEDDKIKCHQ
. ||..| | |||| .|.|||. ||.|| . |||||... . . . |||||||.. . |||.|.|| .. .|.|.|.| |. ..||||
aisaarkpenlsknryrdilpydatrvklkeset...dyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqksslivmlttlverGrvkChq
YWPSFG-AANYGSFQVTLKEVETVADYAIRTFQLQSLHGQGpIKEVRQYHFLVWPDHGVPQYATPLLSFQKRVRNHHKGKPGPMVVHCSAGVGRTGTFIT
|||. . .||.|.|.... .. |..| . |. . . ... | .| |||||||. .. .|.| .|||. ..|| |.|||||||.|||| .|.
yWPetedeleygefsvkcekedetksyvlrelvlkdketke.erkilqlqylaWpdhgvPddsadflefvervrklrsgkeePvvvhCsaGigrtGvlil
IDTMIMKIDAEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAIM
..| ...|.|. | . . || || | .||||||| |. .|||.. .
letalalieaaepvypldivrtmrdqramlvqtasqykfvCeailkvye
|
|||||||||
0045098 | (Phosphotyrosine protein) phosphatases II | 405-655 | 9.9e-71 | 233.7 | In-house | 23-276 (278) | alignment | ||
Range on Protein: 405-655
Range on HMM: 23-276/278.0
FDCSIAQLSDNLAKSRVKEHLPPNDYRVVlstknydsDYICASYVDGYrqRSAFIATQGPMKNTAGDFWRMVWEMKSMIIIMLTNTEENGEEQSVQYWPv
... |.. .||.| | |. || . ||. ||| |||.||| . .|||||||...|. |||||.||... .|.|||. .|.| | .||||
seitpalylgnldknRykdilpydhsrVk........dYINAsyidgy..pkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaqywp.
NpNEEDMYGSFNVVALPEERAlPDYIVRKFKLSHS---KNPDDSRTITHFQYINWPSTSCPKEA--TSMIDLVADVVRIQR------------KSGNGPI
. .. || | | | ||. .||..|.... . .. . ||..||..|..|| ..| . .|...|. . . .. ...||.
e.ggsltygdftvtllseevl.ddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpv
TVHCSDGLGRTGTFCAMFTVLERLkaEQVIDVFSTVKTLRIQRPG-FVNDIDQYEFIHKAALEFVNTFD
|||| |.|||||..|....||.| |...|....||.|| |||| | .||.|.....||... ..
lVHCsaGvgRtGtlvaaylmlell..eggvdlleavkelrsqRpglavqnleqyrflyefllelllrgk
|
|||||||||
subfamily_PTPRB_pd | Subfamily PTPRB | 384-652 | 1.2e-70 | 232.8 | In-house | 23-286 (293) | alignment | ||
Range on Protein: 384-652
Range on HMM: 23-286/293.0
GKTGFQSQFETLESsspTDDDFDCSIAQLSDNLAKSRVKEHLPPNDYRVVL--STKNYDSDYICASYVDGYRQRSAFIATQGPMKNTAGDFWRMVWEMKS
...|. ..|.|.. . | ...|.|. | || | .. || . || | ... .|||| |.|..||... |||||||. .| |||||||| ||
sdlrfseeyeelka...vgkdqavkaaelavnraknrytnilpydhsrvkLaalkdesgsDYinanyipgynsprefiatqGPlpetvddfWrmvwekks
MIIIMLTNTEENGEEQSVQYWPVNPNEEdMYGSFNVVaLPEERALPDYIVRKFKLSHsknPDDSRTITHFQYINWPSTSCPKEATSMIDLVADVVR-IQR
||.|||.. |.| .. .||| . .. .||. .| | .|. | |...|..|... ...|........ || |.......|.| | . |..
siivmltqlvekgkvkCeeYWPadeepv.lyGdikvt.lvaeeeledwvirelkiek...ekeerkvrqyhftsWpdhgvPektktlldfvrtvreaiek
KSGNGPITVHCSDGLGRTGTFCAMFTVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFVN
.. ..||.|||| |.|||||| |. ..|.... |...|.|..| || .| .| .|| |||.. |....
taskrPivvhCsaGvGRtGtfialdrllqaieeedyvdifgivaelReeRnllvqtekqYifihqcvldllr
|
|||||||||
subfamily_PTPN9_pd | Subfamily PTPN9 | 373-652 | 1.4e-69 | 229.4 | In-house | 3-291 (297) | alignment | ||
Range on Protein: 373-652
Range on HMM: 3-291/297.0
IATLKEIAPSSGKTGFQSQFETLESSSPTdDDFDCSiaQLSDNLAKSRVKEHLPPNDYRVVLSTKNYD--SDYICASYVDGYRQRSAFIATQGPMKNTAG
| | . . || | . ... . . ... |..| .| || | | .. | .. ||||.... | |||| |..||||.|. ||||||||.|.|
ieelvayvkekgkrGlskeyaeirnepve.Gtflas..klranleknrytdvlcydetrvvlakvdedeasdyinanfvdGykqkkafiatqGplkktvs
DFWRMVWEMKSMIIIMLTNTEENGEEQSVQYWPVNPNEEDMYGSFNVVALPEErALPDYIVRKFKLSHSKNpDDSRTITHFQYINWPSTSCPKEATSMID
|||||||| . ..|.| | ..|.| . |||| . .. . .|...| . | || ||.......|. ..||..||||.. || |..|.|..|
dfWrmvWeqevlvivmttrvvergrlkcgqyWpleeessaefgdlsvsnveve.eeedykvrvleiknvkt.eesrkvthfqflsWPdyGvPssaaslld
LVADVVRIQRK------------SGNGPITVHCSDGLGRTGTFCAMFTVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFVN
.. | . | . . || |||| |.||||||... |.||. ....||. |||.|| || . .|||| ..| ||.
vlekvrekqalavkelgdewkghpsgPPivvhcsaGiGrtGtfitldiclsrleevgtvdvvetvkllrtqrafsiqtpeqyefcylavleyal
|
|||||||||
subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 98-398 | 3.4e-69 | 228.1 | In-house | 19-277 (392) | alignment | ||
Range on Protein: 98-398
Range on HMM: 19-277/392.0
SDRLEEEYPDIELEWNFTSYAAKLPINHGKNRYVNIIPYDHSRVTL-KPDGNPGSDYINASFIGGLNSPKDYIATQGPIPAAFPDFWRMIWEYNVPTIIM
| . ||. |. . .|. .|| |||| ||.||| .|| | | | |||.|||.| .... | |||.||| .|.. |||||... || ||.|
salffeefhdlpgpdiypqtvaqkeinlkknryknilpydsarvkleviddipdsdylnasyipsfdnekayiasqgpnaaslddfwrmvfqenvttiam
VTNLKEDDkikchqywpsfgaanygsfqvtlkevetvadyairtfqlqslHGQgPIKEVRQYHFLVWPDHGVPQYATPLLSFQKRVRNHHKGKPGPMVVH
||.||| | .|. . | |.|| |||..||.... || | | |. .. |...|
vtklkegd..........................................kgd.dartvaqfhftewPdkdvpkhtssllkfikevkadfGqythpliih
CSAGVGRTGTFITIDTMIMKIDAEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAIMCRDTTIPAVHMATKIATLKEIAPSSGKTGFQSQFETLE
||||||||| |.||... . .||.|||| .| | ||||| || |.. |.|| .. |.| || ||.. ....|. . ... . .|..|
csagvgrtgvvisidsvvahakktrmvdvfnfvtnirrkrpymvqtkeqyafiygavledllwrntlipvvhftdhlqdlstssdGdvrskqlkefrslk
SS
.|
as
|
|||||||||
subfamily_PTPN13_pd | Subfamily PTPN13 | 98-357 | 1e-67 | 223.3 | In-house | 10-269 (273) | alignment | ||
Range on Protein: 98-357
Range on HMM: 10-269/273.0
SDRLEEEYPDI-ELEWNFTSYAAKLPINHGKNRYVNIIPYDHSRVTLKPDGNpgsdYINASFIGGLN--SPKDYIATQGPIPAAFPDFWRMIWEYNVPTI
.. .||. .. || |. .| |. |||| |..|||..||.|. .|. |||||.| .|||.|||.| . |||.|.|| .. |
qqqPaeefkelrelkpldtcevgkkkenkdknryrnvlPydetrvklgdegg....yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaevi
IMVTNLKEDDKIKCHQYWPSFGAA---NYGSFQVTLKEVETVADYAIRTFQLQSLHGqGPIKEVRQYHFLVWPDHGVPQYATPLLSFQKRVRNHHKgKPG
.|||. ||..|.|||.|||. .. ..|.| .|. ....|..... .. | .|| . .| |||||||. |..|| | ..||. .. . |
amvtlekekgkvkchrywPesknkklkvsnrlevellkvqkldgfvvralavkdses.gesrevahlnfvkwPdhgvPssaaellqfvaevrrlqt.dag
PMVVHCSAGVGRTGTFITIDTMIMKIDAEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAI
|.|||||||.||.||.||||... |. . .|. . || .| |. .||| || | ..||||..
PivvhcsaGiGrsGtlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykailevl
|
|||||||||
0037934 | (Phosphotyrosine protein) phosphatases II | 406-650 | 1.8e-66 | 219.5 | In-house | 1-241 (243) | alignment | ||
Range on Protein: 406-650
Range on HMM: 1-241/243.0
DCSIAQLSDNLAKSRVKEHLPPNDYRVVLstknYDSDYICASYVDGYRQrsaFIATQGPMKNTAGD----FWRMVWEMKSMIIIMLTNTEENGEEQSVQY
..|||.| || | |.. || .. ||.| .||||.|........ .||||||...| | ||||.|| .. .|.|||...|.| |. .||
sfsiallpenlsknrysdilpydhsrvkl....egsdyinanliyvtpr...liatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqy
WPvnpNEEdMYGSFNVVALPEERaLPDYIVRKFKLSHSKNPDDSRTITHFQYINWPSTSCPKEATSMIDLVADVVRIQRK-------SGNGPITVHCSDG
|| .|. .|| | | | || |.||.||...|.. . .| .|...|..|..|| ..| . ....|.. .| .... ...||. |||| |
wp...gev.tygdftvtllseeh.lddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaG
LGRTGTFCAMFTVLERLkaeQvIDVFSTVKTLRIQRPG-FVNDIDQYEFIHKAALEF
.|||||..|....|..| . .|....||.|| |||| | .||.|...|.||.
vgRtGtliaaylmllll...g.vdleeavkllreqRpgkavqtpsqyrflyeallel
|
|||||||||
subfamily_PTPN12_pd | Subfamily PTPN12 | 384-652 | 7.3e-66 | 217.0 | In-house | 6-278 (290) | alignment | ||
Range on Protein: 384-652
Range on HMM: 6-278/290.0
GKTGFQSQFETLESSSP---TDDDFDCSIAQLSDNLAKSRVKEHLPPNDYRVVLSTKN--YDSDYICASYVDGYRQRSAFIATQGPMKNTAGDFWRMVWE
|. |...|..| . | ... . . .. . | .| | |. || . ||.||... .|||| |... | .. ..||.|||. .| |||||.||
geeefakefqklkklsekykaekvysteagekeenvkknrykDilPydksrvelskieeeegsdYinanfikgvegkleyiaaqgPLpktlddfWrmiwe
MKSMIIIMLTNTEENGEEQSVQYWPVNPNEEDMYGSFNVVALPEERALPDYIVRKFKLSHSknpDDSRTITHFQYINWPSTSCPKEATSMIDLVADVVRI
.. |..|. . |.| . .||| . .|| ..|.|.| |.. |...| .|. .. ..||... |.| .|| .|. |.|...|...| ..
knveivvmaCrevelgkkkCerYWpeegeeelefgefevtleeekavdddflirtLkveaq...kesrkvyqfhYtaWPDhgvPssaksllelielvrel
QRkSGNGPITVHCSDGLGRTGTFCAMFTVLERLKAEQV---IDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFVN
|. | . |. |||| | ||||| .|. | | ||||.. .|||. | .|| ||. | .|||...|| .|.|.
qe.sedaPlvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelvq
|
|||||||||
subfamily_PTPN1_pd | Subfamily PTPN1 | 103-361 | 1.1e-65 | 216.2 | In-house | 10-277 (290) | alignment | ||
Range on Protein: 103-361
Range on HMM: 10-277/290.0
EEYPDIELEWN-FTSYAAKLPINHGKNRYVNIIPYDHSRVTLKPDGNpgsDYINASFIGGLNSPKDYIATQGPIPAAFPDFWRMIWEYNVPTIIMVTNLK
| | ||. | . |. .|||| |...||| .. ||||||..|. . | ||||||.. . . || ||||.| . ||.|.|| . ...|. ..
eiyldirkeasdfptreaklpenrnlnryrdvspydhsrikleradn...dyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvv
EDDKIKCHQYWPSFGA---A--NYGSFQVTLKEVETVADYAIRTFQLQSLHGQGpIKEVRQYHFLVWPDHGVPQYATPLLSFQKRVRNHH--KGKPGPMV
| ..|||.||||. . ...|.| . |. | .|...|. |. | .|. ..|.. ||| |||. . .|.| .||. . . || |
ekeqikcaqywPqgeeekellledtklkvkliseerksyytvrllelenlktqe.treilhfhyttwpdfgvpespaaflkflfkvresGslssdvGpav
VHCSAGVGRTGTFITIDTMIMKIDAEGI---VDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAIM--CRD
.|||||.||.|||. .||....|.... ||| . . .| | ..||| | .| . |||| . .|
ihcsaGiGrsGtfclvdtclvliekkddlssvdikkvllelrkyrlGliqtadqlrfsylaileGakvikgd
|
|||||||||
subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 383-657 | 2.7e-65 | 215.0 | In-house | 12-299 (301) | alignment | ||
Range on Protein: 383-657
Range on HMM: 12-299/301.0
SGKTGFQSQFETLESSSptddDFDCSIAQLSDNLAKSRVKEHLPPNDYRVVLSTKNY----DSDYICASYVDGYRQRSAFIATQGPMKNTAGDFWRMVWE
...|..|...|.. . | |.. ..| | .| |. . .| |..|..|. .|| |||.|||... .|||.|||||.| ||||..|.
khsnkfeeqykelkege....dksctvglseenkalnrfknitvyddnriilkpkpnldlcqreyinasyidgysekkkfiaaqgpmkktlvdfWrliwq
MKSMIIIMLTNTEENGEEQSVQYWPVNPNEEDMYGSFNVvALPEERALPDYIVRKFKL--------------SHSKNPDDSRTITHFQYINWPSTSCPKE
| . |.|.||..|. .... |||| .|.. .| |.| | .| ..||...|.... . |. .|.... .| ..|| .|
ekpvsivmvtnlkegtkskceqywpnseaeseefgpftv.tlvneqvyPdfvirqlnvkiqdgsnngyierkfkvksdksswdvlqlqvtdWpqdGvvre
ATSMIDLVADVVRIQRKSGNGPITVHCSDGLGRTGTFCAMFTVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFVNTFDNY
.. . ||. |.| | ||. |||||. .|.|..|.. || ||| |.||| .|..| ..|| | ..|| .|... .... . |
prtvLqviddvihrqqkigggpvvVHCSdtVsrsGvYcsvsiglEQckaegVVdvfqvtkavrrskpgaVtTLeqytsiydvidmylqlnsty
|
|||||||||
subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 124-373 | 1.4e-64 | 212.7 | In-house | 33-282 (283) | alignment | ||
Range on Protein: 124-373
Range on HMM: 33-282/283.0
NHGKNRYVNIIPYDHSRVTLKPDGNpgsDYINASFIG---GLNSPKDYIATQGPIPAAFPDFWRMIWEYNVPTIIMVTNLKEDDKIKCHQYWPSFGAANY
|. |||. .|.|.| || ||.. . |||||.|| . |.||..|.|. . |||.|... .. .|.|.|.|.|| .||| ||||. |. .|
nkrknrnqeivpadqwrvelksesr...dyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekitaivmltklqedlrikCsqyWPkrGsedy
GSFQVTLKEVETVADYAIRTFQLQSL-HGQGPIKeVRQYHFLVWPDHGVPQYATPLLSFQKRVRNHHKGKPGPMVVHCSAGVGRTGTFITIDTMIMKIDA
| | |||.. | . |. . |. . . . | . | . | |. | | . . . | ||.|||||.|.|||..||.. . . .. .
Geftvtlrkettsnsfiikelllrvnssakstll.lahyqvidWleygeqaiinslvkfnkvislqteskkgPivvhCstgiGrtavfiaasasvkdalt
EGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAIMCRDTTIPAVHMATKI
| .||.|. |. || | .||| || ..|...|| .| || | || . . |
esvvdvfavvkimreqrmmavqtldqyklvhelvleqalcgdtqiaavdlqsti
|
|||||||||
subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 384-651 | 4.7e-63 | 208.0 | In-house | 22-279 (315) | alignment | ||
Range on Protein: 384-651
Range on HMM: 22-279/315.0
GKTGFQSQFEtlesSSPTDDDFDCSIAQLSDNLAKSRVKEHLPPNDYRVVL--STKNYDSDYICASYVDGYRQRSAFIATQGPMKNTAGDFWRMVWEMKS
| ||. ..| | | . . .|. . | | | . .. . || | .. .|||. |...||| .. .||.||| .. .||||.|.| .
tkngfkqdye....sipggqlhpldvakkienkqknryiniiaydksrvqlpllendphsdyvnanfidGynkkrryiaaqgpnvasvkdfwrlvfeedi
MIIIMLTNTEENGEEQSVQYWPVNpneEDMYGSFNVVALPEErALPDYIVRKFklsHSKNPDDSRTITHFQYINWPSTSCPKEATSMIDLVADVVRIQRK
|.||||. |. .... .||| . . .|| . | || .| || . |. |.. ..| || . || ......|. | . . .
gkivmltnlvegekrkaekywpdk...kviyGkitvtrksee.vnteytvrtl...svvfgdnirevvqlhytswpdmgvpkytiplmnlirtvkqhhtn
SGnGPITVHCSDGLGRTGTFCAMFTVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFV
| |.| ||||.| ||||||... .||....||..|||. .. .| .| . |. ..||.||..| || .
sv.gaivvhcsaGvGrtGtfitldavldqaeaenaidvynfitgvrqnrikmvqvaeqyqfiydalletf
|
|||||||||
subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 411-652 | 8.3e-63 | 207.0 | In-house | 24-269 (274) | alignment | ||
Range on Protein: 411-652
Range on HMM: 24-269/274.0
QLSDNLAKSRVKEHLPPNDYRVVLSTKN---YDSDYICASYVDGYRQR-SAFIATQGPMKNTAGDFWRMVWEMKSMIIIMLTNTEENGEEQSVQYWPVNP
... . | | |. || . ||.|.... ||.|| | |. ||... |..|||||. || |||||... .. .|.|||. .|. |.. ..|.| .
dvfgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneqkCavyfPdae
NE--EDMYGSFNVVaLPEERALPDYIVRKFKLSHSKNpddSRTITHFQYINWPSTSCPKEATSMIDLVADVVRI--QRKSGNGPITVHCSDGLGRTGTFC
. .. || ... . || |||. |..... .|...|. | .|| . |..|....|||..| . ... .|. |||| |.|||| |
dyeiserygdveik.vekiverndysvrklvlkyler...ersvkhywytdWPdhksPddantlldlvleveesreeenaklapvvvhCsaGiGrtGcfi
AMFTVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFVN
|. . .|..|.|.||...| ||..| | |. .|||.||.| ....
aisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralclylk
|
|||||||||
subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 406-649 | 2.9e-62 | 205.8 | In-house | 52-289 (319) | alignment | ||
Range on Protein: 406-649
Range on HMM: 52-289/319.0
DCSIAQLSDNLAKSRVKEHLPPNDYRVVLSTKN--YDSDYICASYVDGYRQRSAFIATQGPMKNTAGDFWRMVWEMKSMIIIMLTnteengEEQSVQYWP
| . | | .| | |. . |. . .| | . |||| ||.|.||... .||.|||..|| |||||.||... |..|| ... ||||
dqtfanldqnkdknriinilafdknvvklerliGeefsdyinasfvtGyqrkdkyiaaqGPldntladfWrmiweyncstivllt......kdkcsqywp
VNPNEEDMYGSFNVVALPEERAlpdYIVRKFKLSHSKNPDDSRTITHFQYINWPSTSCPKEATSMIDLVADVVRIQRK-SGNGPITVHCSDGLGRTGTFC
. .... . .| .. | |.||...||. . | | || | . || |. .. .. || | ...| .. .| |||| | ||||..
lkivikeerfkvkvdsveetae...yvvrdielsedgkekdirkitqfhflGwpdvGvpdypsdlmrlvkkvrhltskenhranivvhcsaGvGrtGvyi
AMFTVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALE
.. ..|.|.| |. .||. .|. || ||. .|.|. || ||. | ||
vldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalle
|
|||||||||
subfamily_PTPN23_pd | Subfamily PTPN23 | 123-357 | 1.6e-61 | 202.6 | In-house | 42-280 (288) | alignment | ||
Range on Protein: 123-357
Range on HMM: 42-280/288.0
INHGKNRYVNIIPYDHSRVTLKpdgNPGSDYINASFIGGLNSP-KDYIATQGPIPAAFPDFWRMIWEYNVPTIIMVTNLKEDDKIKCHQYWPSF-G-AAN
.. |||. .|.||||.||.|. . |||||||. .| . |.||||.|.. . |||.|..| ...|.|... .| .| |...|||. | . .
lyseknrsrdilPyDhnRvklr...gskDDYinAsfvkdlspgcPdfiatqaPlqstlnDFWlmvyeqkssviVmllskeelgkpkvdrYwPedkgetvk
YGSFQVTLKEVETVADYAIRTFQLQSlHGQGPIKEVRQYHFLVWPDHGVPQYATPLLSFQKRVRNHHK----GKPGPMVVHCSAGVGRTGTFITIDTMIM
.| ..||||.|.. . |...|. ... .|.|. .. ||..|||. || | . |..... |.||||||||||||.| . . .
fgdlsvtlksvretethvervlklet.ldadavksvshlqltsWpelGvPasPetllqfldevesayeavqrksktPlvvhCsaGvgRtgvfalvyaavr
KIDA-EGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAI
.... .|..|| . |. .| | .|||. .|. |. .|.|||.
elekgnglldiiqvvsrlreqRrfmvqekeqlkfsyeavleaa
|
|||||||||
subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 385-650 | 1.8e-61 | 202.5 | In-house | 5-265 (283) | alignment | ||
Range on Protein: 385-650
Range on HMM: 5-265/283.0
KTGFQSQFETLESSSPTDDDFDCSIAQlsDNLAKSRVKEHLPPNDYRVVLSTKNYdsDYICASYVD---GYRQRSAFIATQGPMKNTAGDFWRMVWEMKS
..... ..|.|. | | | |.. |. .| | | .| .| . .|| | ... ||| |... |.| .|..|.|...| |||.||.. |
vnnnklfrevlkrlsvpdldadiasad..enkrknrnqeivpadqwrvelksesr..dyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdeki
MIIIMLTNTEENGEEQSVQYWPVNPNEEdmYGSFNvVALPEERALPDYIVRKFKLSHSKNPDDSRTITHFQYINWpsTSCPKEA--TSMIDlVADVVRIQ
|.|||. |. ... |||| . |. || | |.| .| . .|.... | .. .. ..|.|.|.| ... ..| |.. . |. |
taivmltklqedlrikCsqyWPkrGsed..yGeft.vtlrkettsnsfiikelllrvnssakstlllahyqvidW..leygeqaiinslvk.fnkvislq
RKSGNGPITVHCSDGLGRTGTFCAMFTVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEF
..| .||| |||| | |||..|.|. . .. ...| |.|||..|| .| ||.. | ||| ..|...||
teskkgPivvhCstgiGrtavfiaasasvkdaltesvvdvfavvkimreqrmmavqtldqyklvhelvleq
|
|||||||||
subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 406-649 | 1.8e-61 | 203.1 | In-house | 16-253 (284) | alignment | ||
Range on Protein: 406-649
Range on HMM: 16-253/284.0
DCSIAQLSDNLAKSRVKEHLPPNDYRVVLSTK--NYDSDYICASYVDGYRQRSAFIATQGPMKNTAGDFWRMVWEMKSMIIIMLTnteengEEQSVQYWP
| . | | .| | |. . |. . .| | . |||| ||.. ||... .||||||..|| |||||.||... |..|| ... ||||
dqtfanldqnkdknrighilafdknvvklerliGeefsdyinasfitGyqrkdkyiatqGPldntladfWrmiweyncstivllt......kdkcsqywp
VNPNEEDMYGSFNVVALPEERAlpdYIVRKFKLSHSKNPDDSRTITHFQYINWPSTSCPKEATSMIDLVADVVRIQRK-SGNGPITVHCSDGLGRTGTFC
. .... . .| .. | |.||...||. . | |.|. | . || |. .. .. || | ...| .. .| |||| | ||||..
lkivikeerfkvkvdsveesee...yvvrdielsedgkekdirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrtgvyi
AMFTVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALE
.. ..|.|.| |. .||. .|. || ||. .|.|. || ||. | ||
vldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalle
|
|||||||||
subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 383-653 | 2.6e-61 | 202.2 | In-house | 12-278 (281) | alignment | ||
Range on Protein: 383-653
Range on HMM: 12-278/281.0
SGKTGFQSQFETLESSsptDDDFDCSIAQLSDNLAKSRVKEHLPPNDYRVVL--STKNYDSDYICASYVDGYRQRSAFIATQGPMKNTAGDFWRMVWEMK
. ..||....|.|.. . | . .. .| | | . . ||.. . .| ..||| |..|.||.. ..||||||. .. .||.|||| |
ndnaGfieeyeklaai...gvdntataskadenvlknrYsnivaYDatrvkvtpneenkntDYinanfvpgykgekeyiatqgPvPaslvafWqmvweqk
SMIIIMLTNTEENGEEQSVQYWPvNPNEEDMYGSFNVVALPEeRALPDYIVRKFKLshSKNPDDSRTITHFQYINWPSTSCPKEATSMIDLVADVVRIQR
.|.|.|. |.| . .||| ..|.| || . | . | .. . || ||||| ... ..|......|..|| . |.... ... ..| ....
vsaivmvtreieagklkChrYWP.ddnselkygdvtvkstae.eekatyierkfkl..eresgetreveqlaytaWPdhGvPattkellefrkevlklte
KSGNGPITVHCSDGLGRTGTFCAMFTVLERLKAE-QVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFVNT
|. . |. .||| | |||||. |. .......|| . .|| .|. || .| .| . ||||..|| |. ..
kktkaplvihCsaGvGrtGtyialDrlvkaveaeleeldvkavvaelrkernlmvqtvvqyefvykavldaldk
|
|||||||||
subfamily_PTPRN_pd | Subfamily PTPRN | 96-356 | 1.5e-60 | 199.5 | In-house | 26-291 (297) | alignment | ||
Range on Protein: 96-356
Range on HMM: 26-291/297.0
NNSDRLEEEYPDIELEW--NFTSYAAKLPINHGKNRYVNIIPYDHSRVTLKPDGNP-GSDYINASFIGGLNSP-KDYIATQGPIPAAFPDFWRMIWEYNV
.| ||||.|. . . |. .|| . | |||. ...|||||||.|| . . |||||||.| . |||||||... |||.|.|| |
knkdrlekewealcayeaepstkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplastvadfwqmvweqGv
PTIIMVTNLKEDDKIKCHQYWPSFGAANYGSFQVTLK-EVETVADYAIRTFQLQSLHGQGpIKEVRQYHFLVWPDHGVPQYATPLLSFQKRVRNHHKGKP
|...|.|.|.. .|..||| |.. |. ..| | | || .|.| |. |. . . | |.||| ||..||| | .|| |...| ..|.
vvivnltrleeegvkqckrywpdeGsevyhiyevhlvsehiwcddylvrsfylknlqtse.trtvtqfhflswpeegvPasaksllefrrkvnksyrGrs
GPMVVHCSAGVGRTGTFITIDTMIMKIdAEGI--VDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEA
|.|||||.|.||||..| || .. .. . |. .|| . .| |. .|.| .|..| |. |
cpivvhcsdGaGrtGvyilidlvlnrl.lkGvkeidiaatlehlrdqrpglvktkdqfefaltavaee
|
|||||||||
subfamily_PTPN3_pd | Subfamily PTPN3 | 402-649 | 2.4e-60 | 198.8 | In-house | 28-273 (280) | alignment | ||
Range on Protein: 402-649
Range on HMM: 28-273/280.0
DDDFDCSIAQLSDNLAKSRVKEHLPPNDYRVVLSTKNYdsDYICASYVD----GYRQRSAFIATQGPMKNTAGDFWRMVWEMKSMIIIMLTNTEENGEEQ
. . ..|.|....||.| | .. || .. || |. . ||| |.||. . . .||||||...|| |||.|||| || .|.|||.. |.| .
kpglaisaarkpenlsknryrdilpydatrvklkeset..dyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqksslivmlttlverGrvk
SVQYWPVnPNEEDMYGSFNVVALPEeRALPDYIVRKFKLSHsKNPDDSRTITHFQYINWPSTSCPKEATSMIDLVADvVRIQRKSGNGPITVHCSDGLGR
|||| ...| ||.|.|. | .. |..|.. |.. |. ...|.|...||..|| . |.........| || .|.. . |. |||| |.||
ChqyWPe.tedeleygefsvkceke.detksyvlrelvlkd.ketkeerkilqlqylaWpdhgvPddsadflefver.vrklrsgkeePvvvhCsaGigr
TGTFCAMFTVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALE
|| . .. | | . |.. . . |.|.| || .|. .||.|. .| |.
tGvlilletalalieaaepvypldivrtmrdqramlvqtasqykfvCeailk
|
|||||||||
subfamily_PTPN14_pd | Subfamily PTPN14 | 113-357 | 3.1e-60 | 198.7 | In-house | 38-296 (300) | alignment | ||
Range on Protein: 113-357
Range on HMM: 38-296/300.0
NFTSYAAKLPINHGKNRYVNIIPYDHSRVTLKPDGNPGSDYINASFIGGLNS--PKDYIATQGPIPAAFPDFWRMIWEYNVPTIIMVTNLKEDDKIKCHQ
. . ..|||| | |||. ...||...|| |.| . ..||||| | . ..||..|||.. . |||.|.|| .| |.|.|. .|| | |...
dallstaklpenaeknrfkdvlPyednrvelsptkenstgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivmlteeeedgkeksfk
YWPSF----GAANYGSFQVTLKEVETVADYAIRTFQLQSLHGQgPIKEVRQYHFLVWPDHGVPQYATPLLSFQKR---VRNHHKGKP------GPMVVHC
|.|. ...| |.|| | .|. .. ....|. | . ..| . |||||||. .. ||. .. ||.. . . |..|||
yfPkleskkktvefgkfkvttkfsedsdsvittglklkhlpsk.eertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseveskeskPPvlvhC
SAGVGRTGTFITIDTMIMKIDAEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAI
|||||||| |. | .| .. . .|| . .. .| | ..||| .|| |....... .
saGvGrtGvlilsdlliatlehneeidikkvlarLreqrmllvqtlaqYkfvYkvlikyl
|
|||||||||
subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 124-358 | 1.1e-58 | 193.3 | In-house | 20-265 (270) | alignment | ||
Range on Protein: 124-358
Range on HMM: 20-265/270.0
NHGKNRYVNIIPYDHSRVTLKP-DGNPGSDYINASFIGGL-NSPKDYIATQGPIPAAFPDFWRMIWEYNVPTIIMVTNLKEDDKIKCHQYWPSFGAA---
.. ||| .|.| ..||.|.. . .. . |||| .. | ...| |||..|| |.. .||||||| .|..|.|.|.|.|. . || .|||.
gkklnRyadiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkekvk
-NYGSFQVTLKEVETVADYAIRTFQLQslhGQGPIKEVRQYHFLVWPDHGVPQYAT------PLLSFQKRVRNHHKGK--PGPMVVHCSAGVGRTGTFIT
..| .|. . | | .. .|. .| .... ... |||||||. . ||. . ||...| . .|..||||||||||||.|.
ledgkikvlalseekeegyiltrlrle...ekgeerrlvHfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcsaGvgRtGtlia
IDTMIMKIDAEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAIM
.|... .. .. ||. . .. .| | .||. || ||..|..| .
lDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyeflykavveyae
|
|||||||||
subfamily_PTPN23_pd | Subfamily PTPN23 | 382-653 | 1.8e-58 | 192.6 | In-house | 11-282 (288) | alignment | ||
Range on Protein: 382-653
Range on HMM: 11-282/288.0
SSGKTGFQSQFETLESSSPTDdDFDCSIAQLSDNLAKSRVKEHLPPNDYRVVLStkNYDSDYICASYVDGYRQRS-AFIATQGPMKNTAGDFWRMVWEMK
.|||... .|. ||.. . . ||| . | | .. || . ||.| . ||| ||.| . . |||||.|...|..|||.||.| |
ldgktaldkkfkeleqkqdke.arkrsiaiaklyseknrsrdilPyDhnRvklr..gskDDYinAsfvkdlspgcPdfiatqaPlqstlnDFWlmvyeqk
SMIIIMLTNTEENGEEQSVQYWPVNPNEEDMYGSFNvVALPEERALPDYIVRKFKLSHSkNPDDSRTITHFQYINWPSTSCPKEATSMIDLVADVVR---
| .|.||.. || |... .||| . .| .| .. |.| ..| .. .. |..||.. ..| ....| |. .||. |. ...... |
ssviVmllskeelgkpkvdrYwPedkgetvkfgdls.vtlksvretethvervlkletl.dadavksvshlqltsWpelGvPasPetllqfldevesaye
IQRKSGNGPITVHCSDGLGRTGTFCAMFTVLERLKAEQ-VIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFVNT
... . |. |||| | ||||.|. ...... |.... ..|. |..|| || |.. .|..| .| || ..
avqrksktPlvvhCsaGvgRtgvfalvyaavrelekgnglldiiqvvsrlreqRrfmvqekeqlkfsyeavleaarr
|
|||||||||
subfamily_CG7180_pd | Subfamily CG7180 | 388-656 | 2.1e-58 | 192.3 | In-house | 15-295 (296) | alignment | ||
Range on Protein: 388-656
Range on HMM: 15-295/296.0
FQSQFETLESSSPTDDDFDCSIAQLSDNLAKSRVKEHLPPNDYRVVLSTK--NYDSDYICASYVDGYRQRSAFIATQGPMKNTAGDFWRMVWEMKSMIII
|. ... . |. . || . ..|. | | . .|.. ||||.. . .|||| |.|||.. . ..| |..|.|.| ..|||.|.. .. ..
frveyklelkltprleigdCagglrkenreknrdvkvvPyDynRvvLekldGeeksdYinavyvdsflkkkeyivteapkketvdefWrlvydeeisavv
MLTNTEENGEeQSVQYWPVNPneEDMYGSFNvVALPEERALPDYIVRKFKLSHS---------KNPDDSRTITHFQYINWPS-TSCPKEATSMIDLVADV
.||.| . . . .||| . . || . | . ||. ... |.||| . . . |....||. |.. ..| ....|.|. |
vLtktfdfak.mypsywpnks..keqygeif.veiveekqyanlkirtfkltkkivalteqekqvkaetRivklfqlteWeledkvPlstnalielrrrv
VRIQRKS----GNGPITVHCSDGLGRTGTFCAMFTVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFVNTFDN
...| .||. |..||| .|.| ..|. || .. |. .||| |||||..||. |. ...| .| ||.| .. .
rlwrekvdedpeegPvvvvssdGasRsGvylaidanlelvekeeevdvFeavktlrrsRpqLvenveeYkyiYdvlleavlcnkd
|
|||||||||
subfamily_PTPN13_pd | Subfamily PTPN13 | 391-653 | 1.1e-57 | 190.4 | In-house | 16-271 (273) | alignment | ||
Range on Protein: 391-653
Range on HMM: 16-271/273.0
QFETLESSSPTDddfDCSIAQLSDNLAKSRVKEHLPPNDYRVVLSTKNYdsdYICASYVDGY--RQRSAFIATQGPMKNTAGDFWRMVWEMKSMIIIMLT
.|..|. |.| .|.... .| .| | .. || .. || |. . || ||.. .. .||.|||. .|. |||.|||| |. .|.|.|
efkelrelkpld...tcevgkkkenkdknryrnvlPydetrvklgdegg...yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamvt
NTEENGEEQSVQYWPVNPNEEDMYGSFNVVALPEERALPDYIVRKFKLSHSKNpDDSRTITHFQYINWPSTSCPKEATSMIDLVADVVRIQRksGNGPIT
. |.|. . .|||.. |.. . . |.| . | .. ||......|. .|| ..|.....|| . |..|.... .|| | |.|. .|||
lekekgkvkchrywPesknkklkvsnrlevellkvqkldgfvvralavkdses.gesrevahlnfvkwPdhgvPssaaellqfvaevrrlqt..dagPiv
VHCSDGLGRTGTFCAMFTVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFVNT
|||| |.||.||. .. .||. .. .. .|| .|..|| || | | ||| |..||.|| ...
vhcsaGiGrsGtlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykailevlks
|
|||||||||
subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 401-651 | 1.2e-57 | 190.2 | In-house | 30-277 (315) | alignment | ||
Range on Protein: 401-651
Range on HMM: 30-277/315.0
TDDDFDCSIAQLSDNLAKSRVKEHLPPNDYRVVL--STKNYDSDYICASYVDGYRQRSAFIATQGPMKNTAGDFWRMVWEMKSMIIIMLTNTEENGEEQS
| . .|. ..| | | |. || . ||.| .. ||||| |||. .. . |.||.||| | . ||||||.. | |.|.|. .|. .
dPdiyrqrvaretinfkknryknilPldsarvkleviddsPdsdyinasyiksvdddkayiasqgPlkasvddfwrmvlqekvttivmvtkkqegdkikc
VQYWPVNPNEEDMYGSFNVVALpEERALPDYIVRKFklsHSKNPDDSRTITHFQYINWPSTSCPKEATSMIDLVADVvRIQRKSGNGPITVHCSDGLGRT
|||| . . .||..| | . | | ..||. .. ..|||.| ||. .|| .|...|.. |. .| . .... . .. |||| | |||
rqywPdrkadsvefGsikvell.sleadtdgvarkl...vtrkseesrtvtqfqftewPdkGvdkqtssllklikev.kadngkkefsllvhcsaGvGrt
GTFCAMFTVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFV
| .... |....| ....||| .||.|| .|| .|. ..| ||. | || .
Gvvisidevvaqikrtrsvdvfnfvknlrakrpylvqteeeyafiydavledl
|
|||||||||
subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 399-651 | 1.5e-57 | 190.2 | In-house | 32-288 (325) | alignment | ||
Range on Protein: 399-651
Range on HMM: 32-288/325.0
SPTDDDFDCSIAQLSDNLAKSRVKEHLPPNDYRVVLSTKNYD--SDYICASYVDGYRQRSAFIATQGPMKNTAGDFWRMVWEMKSMIiIMLTNTEENGEE
|.|| .| . .| || | |. .. . |||| ||. | |||| |||. .... |.|.| |. .| .|.||.| . .. . ....| ..|..
lpsddgiakkvamkpenkaknrfknvvaldksrvvletkkddpssdyinasylrddkkkdvflaaqaPltatindlWrlvldWrcsv.vvvlneldlgkd
QSVQYWPVNPNEEDMYGSFNVVALPEERAlPDYIVRKFKLSHSKNpDDSRTITHFQYINWPSTSCPKEATSMIDLVA---DVV-RIQR-KSGNGPITVHC
. .||| . . .|...| | ||. |.... |. ..|.. ||. |. .| ...| .. | |.. . .|| |||
rcavywpkemgksktfGglevklrtieei.sdyvhrvldvkqvkk.GetrsvkqfqlqswddmGvqkrpatlisilqlvkavservtantkastpilvhc
SDGLGRTGTFCAMFTVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFV
|.|.||||.| .....|... | .|.| || || .|| |. .||| .|..| |..
saGvGrtGvfislysalakvieesrvdifgfvkklrkdrpsmvetvdqyiliyealveay
|
|||||||||
subfamily_CG7180_pd | Subfamily CG7180 | 124-361 | 2.1e-57 | 189.0 | In-house | 42-294 (296) | alignment | ||
Range on Protein: 124-361
Range on HMM: 42-294/296.0
NHGKNRYVNIIPYDHSRVTLK-PDGNPGSDYINASFIGGLNSPKDYIATQGPIPAAFPDFWRMIWEYNVPTIIMVTNLKEDDKiKCHQYWPSFGAANYGS
| .|||.|...|||. || |. ||. ||||||... .. .|.|| |..| . .|||.... .. .....|. . | ....||| . ..||
nreknrdvkvvPyDynRvvLekldGeeksdYinavyvdsflkkkeyivteapkketvdefWrlvydeeisavvvLtktfdfak.mypsywpnkskeqyge
FQVTLKEVETVADYAIRTFQLQSL---------HGQGPIKEVRQYHFLVWPD-HGVPQYATPLLSFQKRVRNHHKGK-----PGPMVVHCSAGVGRTGTF
. | . |... |. ||||.|. . . . . |..... .|. . || .. |. . .||| . ||.||..| |..|.| .
ifveiveekqyanlkirtfkltkkivalteqekqvkaetRivklfqlteWeledkvPlstnalielrrrvrlwrekvdedpeegPvvvvssdGasRsGvy
ITIDTMIMKIDAEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAIMCRD
..|| . ... |. ||.|..|. .| |. .|.. .| .. .|||..|
laidanlelvekeeevdvFeavktlrrsRpqLvenveeYkyiYdvlleavlcnk
|
|||||||||
subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 406-651 | 2.2e-57 | 189.3 | In-house | 34-276 (515) | alignment | ||
Range on Protein: 406-651
Range on HMM: 34-276/515.0
DCSIAQLSDNLAKSRVKEHLPPNDYRVVL--STKNYDSDYICASYVDGYRQRSAFIATQGPMKNTAGDFWRMVWEMKSMIIIMLTNTEENGEEQSVQYWP
..|| | | | |. || . || | | .|||. |||. .. |.||.||| | . ||||.|.. . |.|.|. .|. . .|||
pqtvaqeeinfkknryknilPydsvrvklevindnPhsdyfnasyipsfdndkayiasqgPnkasvddfWrlvlqenvttiamvtklkegdkikcgkyWP
VNPNEEDMYGSFNVVALPEErALPDYIVRKFKLShsKNpDDSRTITHFQYINWPSTSCPKEATSMIDLVADVvRIQRKSGNGPITVHCSDGLGRTGTFCA
| . .||..| . | | . | ||... |. |||||.| |.. .|| ||...|.. |. .| . .. . |. .||| | |||| ...
dkpgdsvkfGsikvelvsle.actggikrkltvl..kg.ddsrtvtqfhfteWPdkGvpkhtssllklikev.kadhgqythpliihcsaGvGrtGvvis
MFTVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFV
. |. . | ...||| .|. .| .|| .| .|| ||. | || .
idsvvahakttrmvdvfnfvtnirqkrpylvqtqeqyafiygavledl
|
|||||||||
subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 85-365 | 7.6e-57 | 187.7 | In-house | 6-287 (439) | alignment | ||
Range on Protein: 85-365
Range on HMM: 6-287/439.0
DFIEMMALLQSNNSDRLEEEYPDIELE-WNFTSYA--AKLPINHGKNRYVNIIPYDHSRVTL-KPDGNPGSDYINASFIGGLNSPKDYIATQGPIPAAFP
.| | . |. |. . ..|.. |. ... | | .. |||| .. ..||.|||| . | | | |||| .| | .| ||||||| .
efqehvekldknkqeifkeifekinstspdyaciaslaaqeydqtknrykdvgafdhtrvtlqeipgvphshyinanyikGyyddklyiatqgpkkettd
DFWRMIWEYNVPTIIMVTNLKEDDKikchqYWPSFGAANYGSFQVTLKEVETVADYAIRTFQLQSLHGQGP-IKEVRQYHFLVWPDHGVPQYATPLLSFQ
||||...| .. ||.|.||| | | |||| . . || | . .|.|| |.. . .. . | |.|.. |||. || |. .| |
dfwrlviekktvtivmltnlvesyk.....ywpsdaevcygdiavrvdrnielpnyvirgfkvfnerdttekertvlqfhyiawpdknvpaqashvldfl
KRVRN-HHKGKPGPMVVHCSAGVGRTGTFITIDTMIMKIDAEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAIMCRDTTIP
. . | . ||.||||||||||||| |..| . .. .| ||| |. .| |. |||. || |.. |.|| |. |...
rainsandkeeygpvvvhcsagvGrtGtiialdialeqlklenkvdikgivkvlrkqrkqmvqalcqyvfiynavledivyGdiavt
|
|||||||||
0051429 | (Phosphotyrosine protein) phosphatases II | 149-377 | 4.5e-56 | 185.7 | In-house | 2-244 (272) | alignment | ||
Range on Protein: 149-377
Range on HMM: 2-244/272.0
PGSDYINASFIGGLNS---PKDYIATQGPIPAAFPDFWRMiWEYNVPTIIMVTNLKEDDKIKCHQYWP------------SFGAANYGSFQVTLKEVETV
| |.||||...||... |. .....|| |. ||||. .|... ||...... | .. ||..||| |. .|| . ||| ..|.
plsgyiNardvggygrvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseell
ADYAIRTFQLQSLHGQGPIKEVRQYHFLVWPDHGVPQYAtpLLSFQKRVRNhhkgkPGPMVVHCSAGVGRTGTFITIDTMIMKIDAEGIVD--------I
|| .|...| |.. | . ||...|.. |||||||| | ||.. . ... .||..||||||..||||.. .. ... ...| ||| .
ldyilrellltlllsagearevmhlhytdwpdhgvpqea..llellellld.....ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlyl
FNFVRGMRFCRNYMVQTASQYDFLHHAILEAiMCRDTTIPAVHMATKIATLK
...|. .| .| ..||| || ||..|.||. ... ....| .... .....
eeaveelraqrpgavqteeqylflyeallel.lrsllsvraeyllaaldaid
|
|||||||||
subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 407-653 | 4.6e-56 | 185.1 | In-house | 43-286 (297) | alignment | ||
Range on Protein: 407-653
Range on HMM: 43-286/297.0
CSIAQLSDNLAKSRVKEHLPPNDYRVVLSTKNYD--SDYICASYVDGYRQrsAFIATQGPMKNTAGDFWRMVWEMKSMIIIMLTNTEENGEeQSVQYWPV
|. |. ||| | || . || | | | |||. ||.| |... .|.|| |||.| |||.||.. . .|.||.. .|. . . .||.
qtvaekkvnfeksRYkniLPydssRvkLaivnddpdsDyvnasfvkgnkh..rlittqmPmkatvadfWamvldeqvstivmlnddnerdk.kcaryWsd
NPNEEdmYGSFNVVALPEERAlPDYIVRKFKLSHSKnPDDSRTITHFQYINWPSTSCPK--EATSMIDLVADVVRIQRKSGNGPITVHCSDGLGRTGTFC
. . .|. || | .. .| |.......| . | . .|...||. . .. .|.|...|. .| . .||. |||. |.|||| ..
kgvtt..fGdvsvvllsvser.eGfikrelevtkgk.akarrvvkqyqfveWPdkaverkdsassllklisevrkdfsqnaegPllvhclaGvGrtgvll
AMFTVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFVNT
.. |. . | |. .|.| .|| || .|| .| .||.|...| ||.. .
tidsvvaeakrekevdifglvkklrqerpylvqtkeqykfvyvavlealls
|
|||||||||
subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 94-363 | 1.1e-55 | 183.5 | In-house | 10-299 (301) | alignment | ||
Range on Protein: 94-363
Range on HMM: 10-299/301.0
QSNNSDRLEEEYPDIELEWNFTSYAAKLPINHGKNRYVNIIPYDHSRVTLKPDGN---PGSDYINASFIGGLNSPKDYIATQGPIPAAFPDFWRMIWEYN
...|...||.| ... . . .. |. ||. || .||. |..||| | .|||||.| | .. | .||.|||. ||||.||..
aakhsnkfeeqykelkegedksctvglseenkalnrfknitvyddnriilkpkpnldlcqreyinasyidgysekkkfiaaqgpmkktlvdfWrliwqek
VPTIIMVTNLKEDDKIKCHQYWPSFG--AANYGSFQVTLKEVETVADYAIRTFQLQSLHGQG--------------PIKEVRQYHFLVWPDHGV-PQYAT
. .|.|||||||. | ||.||||. ..| |.|||.. .. |. || .... .| . ..| |.. ||..|| ....|
pvsivmvtnlkegtkskceqywpnseaeseefgpftvtlvneqvyPdfvirqlnvkiqdgsnngyierkfkvksdksswdvlqlqvtdWpqdGvvreprt
PLLSFQKRVRNHHKGKPGPMVVHCSAGVGRTGTFITIDTMIMKIDAEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAIMCRDTT
| . .. . .| ||.|||||..|.|.|...... . |||.||.|. .. .| . .|.| || ... .| . ... .|
vLqviddvihrqqkigggpvvVHCSdtVsrsGvYcsvsiglEQckaegVVdvfqvtkavrrskpgaVtTLeqytsiydvidmylqlnsty
|
|||||||||
0041856 | (Phosphotyrosine protein) phosphatases II | 124-364 | 5.3e-55 | 181.1 | In-house | 1-178 (182) | alignment | ||
Range on Protein: 124-364
Range on HMM: 1-178/182.0
NHGKNRYVNIIPYDHSRvtlkpdgnpGSDYINASFIGGLNSPKDYIATQGPIPAAFPDFWRMIWEYNVPTIIMVTnlkeddkikCHQYWPsfgaanygsf
|. ||||..|.|||||| ..|||||... | ....|||||| . ..||.||..|... ||...| ...|||
nldknrysdilpydhsr.........dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt.........eelywp..........
qvtlkevetvadyairtfqlqslhgQGPIKEVRQYHFLVWPDHGVPQyATPLLSFQKRVRNhhkgKPGPMVVHCSAGVGRTGTFITIDTMIMKidaeGiV
. ... ||..| ||||||| ||.| ..|.. ..|| .||||||||||||.. .. |. . | |
.........................ellerlgiqylylpwpDhgvpd.ldelldfieevle....eggpvlVHCsaGvgRtgtlvaaylmkkl....g.v
DIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAIMCRDTTI
.... |. .| .|. ||.| .|| ||. |.|| .....|..
sleeavklvrsrRpgmvitpnqyfflqlallellllkktrp
|
|||||||||
subfamily_PTPN14_pd | Subfamily PTPN14 | 393-652 | 6.1e-55 | 181.3 | In-house | 27-297 (300) | alignment | ||
Range on Protein: 393-652
Range on HMM: 27-297/300.0
ETLESSSPTDDDFDCSIAQLSDNLAKSRVKEHLPPNDYRVVL-STKNYDSDYICASYVDGY--RQRSAFIATQGPMKNTAGDFWRMVWEMKSMIIIMLTN
| .. | ..| |.| .| |.|.|. || .| || | .||. ...|| || . .. .|..|||...| |||.|||| . .|.|||.
teyeripkkredallstaklpenaeknrfkdvlPyednrvelsptkenstgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivmlte
TEENGEEQSVQYWPVN--PNEEDMYGSFNVVALPEERAlPDYIVRKFKLSHSKNpDDSRTITHFQYINWPSTSCPKEATSMIDLVADVVRIQRKS-----
.||.| |.|..|.| . ... .| |.|.. | . . .| ...|| | . ||. |.||..|| .|.. ..... . .| ..||.
eeedgkeksfkyfPkleskkktvefgkfkvttkfseds.dsvittglklkhlps.keertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseve
---GNGPITVHCSDGLGRTGTFCAMFTVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFVN
. |. ||||.| |||| ... |. ...||. .....|| || .|. . ||.|..|. .....
skeskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLreqrmllvqtlaqYkfvYkvlikylk
|
|||||||||
subfamily_PTPRN_pd | Subfamily PTPRN | 389-653 | 6.3e-55 | 181.0 | In-house | 32-294 (297) | alignment | ||
Range on Protein: 389-653
Range on HMM: 32-294/297.0
QSQFETLESSspTDDDFDCSIAQLSDNLAKSRVKEHLPPNDYRVVLSTKN--YDSDYICASYVD-GYRQRSAFIATQGPMKNTAGDFWRMVWEMKSMIII
. ..|.| . .. ...|. .|. | |.|. || .. || |.... .|||| || . ...|.||||||. .| |||.|||| ...|.
ekewealcay..eaepstkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplastvadfwqmvweqGvvviv
MLTNTEENGEEQSVQYWPVNpnEEDMYGSFNVVALPEERALPDYIVRKFKLSHSKNpDDSRTITHFQYINWPSTSCPKEATSMIDLVADVVRIQRKsGNG
.||. ||.| .| .||| . ...|. ..| . | ||.|| | | .. ...||.| | .. ||....| .| |.... | . |
nltrleeegvkqckrywpde..Gsevyhiyevhlvsehiwcddylvrsfylknlqt.setrtvtqfhflswpeegvPasaksllefrrkvnksyrG.rsc
PITVHCSDGLGRTGTFCAMFTVLERL-KAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFVNT
|| |||||| ||||..... ||.|| | . ||. .|.. || ||||.|. ||.||. .| | ||.
pivvhcsdGaGrtGvyilidlvlnrllkGvkeidiaatlehlrdqrpglvktkdqfefaltavaeevna
|
|||||||||
subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 117-354 | 1.5e-54 | 179.8 | In-house | 31-274 (287) | alignment | ||
Range on Protein: 117-354
Range on HMM: 31-274/287.0
YAAKLPINHGKNRYVNIIPYDHSRVTLKPDGNPGSDYINASFIGGLNSPKDYIATQGPIPAAFPDFWRMIWEYNVPTIIMVTNLKEDDKIKCHQYWPSFG
||. . |||| ...|.|..|| | .|. ||||||| .. . . . .||.||||.|. ||||...| .. ..|..| |. . ||..|||
kaaeelaavkknryadvlPiddtrvllsaegelGsdyinanyvasytddeafiaaqgPiaatvrdfwravletrsasvitmtreveearlkcykywPere
A-ANYGSFQVTLKEVE-TVADYAIRTFQLQSLHGQGpIKEVRQYHFLVWPDHGVPQYATPLLSFQKRVRNHH-----KGKPGPMVVHCSAGVGRTGTFIT
| . |.| . . .|..|...| |... . |.|...| |||.... | |. | |..| . ||.|||...|.||.|....
vPmrvGGysvvlldydikePeygvralrlidletre.arvvkqldllswPdkvlaPtavglirfvldvkqhielardasevGPlvvhddvGiGrsGilla
IDTMIMKIDAEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAIL
. ... . | ||. . | .| |. .||.. |. .| |.
tlvlvsrledlGrvdvaavvirlreyraalvqavvqlrllyealv
|
|||||||||
subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 388-653 | 2.6e-54 | 179.0 | In-house | 12-279 (287) | alignment | ||
Range on Protein: 388-653
Range on HMM: 12-279/287.0
FQSQFETLESSSpTDDDFDCSIAQLSDNLAKSRVKEHLPPNDYRVVLS-TKNYDSDYICASYVDGYRQRSAFIATQGPMKNTAGDFWRMVWEMKSMIIIM
. ....| | . |. . | | . || .| ||.|| . .. |||| | || .|.. ||||.|||. | .||||.|.| .| .|.
vdkevdalkeds.esstatfkaaeelaavkknryadvlPiddtrvllsaegelGsdyinanyvasytddeafiaaqgPiaatvrdfwravletrsasvit
LTNTEENGEEQSVQYWPVNpNEEDMYGSFNVVALPEERALPDYIVRKFKLSHSKNpDDSRTITHFQYINWPSTSCPKEATSMIDLVADV---VRIQRK-S
.| |.. . .||| . . . | . ||.| . |.| || ..| . . ..| . .....||. . . | ..| .| || . ..|. |
mtreveearlkcykywPer.evPmrvGGysvvlldydikePeygvralrlidlet.rearvvkqldllswPdkvlaPtavglirfvldvkqhielardas
GNGPITVHCSDGLGRTGTFCAMFTVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFVNT
. ||. ||.. |.||.|.. |......||. .|| .| || .| ..|. . |. .. .| . .|
evGPlvvhddvGiGrsGillatlvlvsrledlGrvdvaavvirlreyraalvqavvqlrllyealvtyykt
|
|||||||||
subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 410-653 | 2.9e-53 | 175.6 | In-house | 15-266 (270) | alignment | ||
Range on Protein: 410-653
Range on HMM: 15-266/270.0
AQLSDNLAKSRVKEHLPPNDYRVVLSTKNYD--SDYICASYVDGYRQ-RSAFIATQGPMKNTAGDFWRMVWEMKSMIIIMLTNTEENGEEQSVQYWPVNP
. . . | .. || ||.|.. . | . || | || |. . . ..||..||...| .||||.|| |. |.|.|. ||.| .. .||| .|
peaargkklnRyadiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaep
NE--EDMYGSFNVVALPEERAlPDYIVRKFKLShskNPDDSRTITHFQYINWPSTSCPKEAT------SMIDLVADVVRIQRKSGNG-PITVHCSDGLGR
.| . ..| .|.|| ||.. ||... .| . ..| ..||.| .|| . |.|. ... ....| | ... .. |. ||||.|.||
kekvkledgkikvlalseeke.egyiltrlrle...ekgeerrlvHfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcsaGvgR
TGTFCAMFTVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFVNT
|||. |. .... |. .. .|| . .. || .|. .|. .||||..|| .|....
tGtlialDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyeflykavveyaer
|
|||||||||
0036282 | (Phosphotyrosine protein) phosphatases II | 150-350 | 6.1e-53 | 174.4 | In-house | 1-163 (174) | alignment | ||
Range on Protein: 150-350
Range on HMM: 1-163/174.0
GSDYINASFIGGLNSPKDYIATQGPIPaafpdFWRMIWEYNVPTIIMVTNLKEDDKIKCHQYWPSfgaanygsfqvtlkevetvadyairtfqlqslHGQ
||||||||.... .. .||.||| . ||.|..|... |..|....||... ||..|||. . .
gsdyinaspldlsyitprliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe................................lre
GPIKEVRQYHFLVWPDHGVPQYATpLLSFQKRVRNHHKG-KPGPMVVHCSAGVGRTGTFITIDTMIMKIDaEGIVDIFNFVRGMRFCRNYMVQTASQYDF
. ... ||..| ||||||| .. ||.| |.|..... . ||..||||||||||||.. .. |.. . |. ||....|| .|..| .|||| ||| |
dlerlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtpsQyrf
LH
|.
ly
|
|||||||||
subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 388-651 | 1.3e-52 | 173.7 | In-house | 22-279 (439) | alignment | ||
Range on Protein: 388-651
Range on HMM: 22-279/439.0
FQSQFETLESSSPtDDDFDCSIAQLSDNLAKSRVKEHLPPNDYRVVL--STKNYDSDYICASYVDGYRQRSAFIATQGPMKNTAGDFWRMVWEMKSMIII
|. ||...| || | ..|.| . . .| | |. . . ||.| | || | |..|| . .|||||| |.|. ||||.|.| |.. |.
fkeifekinstsp.dyaciaslaaqeydqtknrykdvgafdhtrvtlqeipgvphshyinanyikGyyddklyiatqgpkkettddfwrlviekktvtiv
MLTNTEENGEeqsvqYWPVNpnEEDMYGSFnVVALPEERALPDYIVRKFKLSHSKN-PDDSRTITHFQYINWPSTSCPKEATSMIDLVADVVRIQRKSGN
|||| | ||| . .| .|| .| . ||.|..| ||. .. . ||. .|.|| || | .|. ..|.. . . |
mltnlvesyk.....ywpsd..aevcygdi.avrvdrnielpnyvirgfkvfnerdttekertvlqfhyiawpdknvpaqashvldflrainsandkeey
GPITVHCSDGLGRTGTFCAMFTVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFV
||. |||| |.||||| |. ||.||.|. .|. || || || .|... || ||..| || .
gpvvvhcsagvGrtGtiialdialeqlklenkvdikgivkvlrkqrkqmvqalcqyvfiynavledi
|
|||||||||
subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 385-651 | 3.4e-49 | 162.2 | In-house | 5-259 (267) | alignment | ||
Range on Protein: 385-651
Range on HMM: 5-259/267.0
KTGFQSQFETLESSSPTDDDFDCSIAqlSDNLAKSRVKEHLPPNDYRVVLSTKNYDsdYICASYVDGYRQRSAFIATQGPMKNTAGDFWRMVWEMKSMII
.. .. .|| .. |.| .||| ..| .. |. . || .| ||.|.||. . || ||||.||... |||.||.|.||| .||. .. . | .|
eceiekefelikkisdtsstisqsia..eknqernrlddnlpyddtrvilrtkeee..yinasyvegyktknafivtqdplkntitdfltvihdqkvpvi
IMLTNTeenGEEQSVQYWPVNPNEEDMYGSFNVVAlPEERALPDYIVRKFKLSHsKNpDDSRTITHFQYINWPSTSCPKEatSMIDLVADVVRIQRKSGN
..||.. .... ..|| . . | . | |. || . ..| || . .. .| . | .| . | . |.. . . | . ||
vlltkv...ftdnirlfwPPkmgqakkyqdltveh.slekeendyqiitlelkf.kn.esahnvtlyyykkwnintnnkp..ylkplfgilaknqlengn
GPITVHCSDGLGRTGTFCAMFTVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFV
|. |.||||.||.||| . . |||.| |.| |.| .. .| ||.|.|. ..| .||. |.
rPlvvacsdGvGrsGtflvidsqleraktegvsdifdflrkirsqriglvdtkeryiyihellaeya
|
|||||||||
0051429 | (Phosphotyrosine protein) phosphatases II | 441-653 | 6e-48 | 159.1 | In-house | 4-227 (272) | alignment | ||
Range on Protein: 441-653
Range on HMM: 4-227/272.0
SDYICASYVDGYRQ---RSAFIATQGPMKNTAGDFWRMvWEMKSMIIIMLTNTEENGEEQSVQYWP---------VNPNEEDMYGSFNVVALPEERALPD
|.|| |..|.|| . . ......||...|| ||||. .|.. |..|...|| | .. .||| .. .... . .| | .| |.|
sgyiNardvggygrvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseellld
YIVRKFKLSHSKNPDDSRTITHFQYINWPSTSCPKEAtsMIDLVADVVRiqrksgNGPITVHCSDGLGRTGTFCAMFTVLERLKAEQVID--------VF
||.|.. |.. .....|...|..|..|| . |.|| ...|.. . . .||. |||| | .||||..|.. .|... .|...| ..
yilrellltlllsagearevmhlhytdwpdhgvpqea..llellellld......ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlyle
STVKTLRIQRPGFVNDIDQYEFIHKAALEFVNT
.|. || ||||.| . .||.|...|.||....
eaveelraqrpgavqteeqylflyeallellrs
|
|||||||||
subfamily_PTPN1_pd | Subfamily PTPN1 | 399-651 | 7.2e-48 | 157.8 | In-house | 19-271 (290) | alignment | ||
Range on Protein: 399-651
Range on HMM: 19-271/290.0
SPtddDFDCSIAQLSDNLAKSRVKEHLPPNDYRVVLSTKnyDSDYICASYVDGYRQRSAFIATQGPMKNTAGDFWRMVWEMKSMIIIMLTNTEENGEEQS
. ||... |.| | .. | .. | . |..| . | ||| || |. . . .| ||||. ||.. ||.|||| || ..|| . |... .
as...dfptreaklpenrnlnryrdvspydhsriklera..dndyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvvekeqikc
VQYWPVNPNEEDMYG---SFNVVALPEERAlPDYIVRKFKLSHSKnPDDSRTITHFQYINWPSTSCPKEATSMIDLVADVVRIQR-KSGNGPITVHCSDG
.|||| . .|. . ...| . ||| |.||...| | ...|.|.|| |. || . |. ....... .| . .| || .||| |
aqywPqgeeekellledtklkvkliseerk.syytvrllelenlk.tqetreilhfhyttwpdfgvpespaaflkflfkvresGslssdvGpavihcsaG
LGRTGTFCAMFTVLERLKAEQV---IDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFV
.||.|||| . |.| ...... .|. .. || .| |.. || .| . | || .
iGrsGtfclvdtclvliekkddlssvdikkvllelrkyrlGliqtadqlrfsylaileGa
|
|||||||||
subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 415-649 | 5.6e-47 | 155.0 | In-house | 3-237 (237) | alignment | ||
Range on Protein: 415-649
Range on HMM: 3-237/237.0
NLAKSRVKEHLPPNDYRVVLSTKNYDSDYICASYVDGYRQ-RSAFIATQGPMKNTAGDFWRMVWEMKSMIIIMLTNTEENGEEQSVQYWPvNPNEEDMYG
| .|.| . . |||| .|||| |.|..|. .||.|||.... |||.|||. | .|.||| |. |.. .||| . .. ||
nkiknrygnivaydhsrvvlkgagsgsdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywp.stdqpaayg
SFNvVALPEERALPDYIVRKFKLSHSKNPDDSRTITHFQYINWPSTSCPKEATSMIDLVADVVRIQRK-SGNGPITVHCSDGLGRTGTFCAMFTVLERLK
. |.| . .. || || . ||. . . | | .|. || |....... . ... .. | || .||| |.|||| | . ..| . |
vlt.vslkkkeefsdytvrslllskrltlkevrlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlrqak
AEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALE
..|.|.. |... .|| .. ||| |||.. ||
ekkvvdiynyvysieedrpyiiqtkdqyvfihqtile
|
|||||||||
0043147 | (Phosphotyrosine protein) phosphatases II | 148-350 | 1.4e-46 | 153.6 | In-house | 2-154 (172) | alignment | ||
Range on Protein: 148-350
Range on HMM: 2-154/172.0
NPGSDYINASFIGGLNSPKDYIATQGPIPAAFPDFWRMIWEYNVPTIIMVTNLkeddkikchqywpsfgaanygsfqvtlkevetvadyairtfqlqSLH
..||||||||.. . |...|||||| . ..|||||..|... .|...|.| .
degsdyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltel............................................lyd
GQGPIKEVRQYHFLVWPDHGVPqYATPLLSFQKRVRN-HHKGKPGPMVVHCSAGVGRTGTFITIDTMImkidaEGIvDIFNFVRGMRFCRNYMVQTASQY
... ... ||..| ||||||| . ||.| . ... ... . ||..||||||||||||.. .. |. .|. .... |. .| .|...||. |||
pellerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml.....lgl.sleeavalvrekRpgavqnpsqy
DFLH
||.
rfly
|
|||||||||
0046846 | (Phosphotyrosine protein) phosphatases II | 144-355 | 2.8e-45 | 149.5 | In-house | 5-171 (176) | alignment | ||
Range on Protein: 144-355
Range on HMM: 5-171/176.0
KPDGNPGSDYINASFIGGLnspkDYIATQGPIPAAFPDFWRMIWEYNVPTIIMVTNLKEDDKIKCHQYWPSFGAANYgsfqvtlkevetvadyairtfql
.. ....|||||..| | .||||||.| ..||..|..|... .....|...| ...||..||| . ....
llgldldldyinanlilgs....rpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgi.......................
qslhgqgpikevrQYHFLVWPDHGVPQYaTPLLSFQKRVRNHHKGKpGPMVVHCSAGVGRTGTFITIDTMIMkidaEGIVDIFNFVRGMRFCRN-YMVQT
||..| |||||||.. . ||.. . .|.. | . || .||||||.|||||.. .. .. | ..... .. .| .| ..|||
.............qylhlpwpDhgvpdl.elllellefirealkeg.gpvlVHCsaGigRtgtlvaayllel....ekglsveealalvreqRplgavqt
ASQYDFLHHAILE
.|| ||....|.
peQyrflyefell
|
|||||||||
0049772 | (Phosphotyrosine protein) phosphatases II | 97-356 | 5.3e-45 | 149.8 | In-house | 19-279 (314) | alignment | ||
Range on Protein: 97-356
Range on HMM: 19-279/314.0
NSDRLEEEYPDIELEWNFTSYAAKLPINHGKNRYVNIIPYDhSRVTLKPDGNPGSDYINASFIGGLnspKDYIATQGPIPAAFPDF----------WRMI
.. .|. . .... ..| ..|.|. |. |||| .|.|.| .|| |. .. ||||||||.. | ...|||||| . . || |||.
lklllvlnrrslsvlpeltilvadlflnrdknryldilpad.nrvilpglpvsgsdyinasyvdgf...lkfIatqgpleitvvdfreepvlyyngwrmv
--WEYNVPTIIM---------------------VTNLKEDDkikchqywPSFGAANYGSFQvtlkevetvadyairtfqlqSLH--GQGPIKEVRQYHFL
...|| .| | ..| . . ||.. .. . . .. . ... .|. .
lrgdlnvrdivmsrdevladelsrLdaAlgKtpllildgng........neptaadlellk....................eelydpelferlgikylri
VWPDHGVPqYATPLLSFQKRVRNHhkGKPGPMVVHCSAGVGRTGTFITIDTMIMKIDAeGIVDIFNFVRGMRFcRN---YMVQTASQYDFLHHAILEA
.||...| ...| . .... |.|| .|||.||.||||||.... .... . . .....|| .|. | .... || | ..|.||.
pvpDgsap.lledfdeflefieea..dkggpvlvHCkaGkgRtgtfvvaaylmkllgv.sleealedvrlkRp.inpnpgfieqleqyefilealley
|
|||||||||
0036282 | (Phosphotyrosine protein) phosphatases II | 441-645 | 4.2e-44 | 145.6 | In-house | 2-164 (174) | alignment | ||
Range on Protein: 441-645
Range on HMM: 2-164/174.0
SDYICASYVDGYRQRSAFIATQGPMKntagdFWRMVWEMKSMIIIMLTNTEENGEEQSVQYWPVnpneedmygsfnvvalpeeralpdyivrkfklshsK
|||| ||..|... . .||.|||.. ||.|..| .. ...||.. .|.| . .||| .
sdyinaspldlsyitprliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe...................................l
NPDDSRTITHFQYINWPSTSCPKEATsMIDLVADVVRIQRKSGNGPITVHCSDGLGRTGTFCAMFTVLERLKaEQVIDVFSTVKTLRIQRPGFVNDIDQY
| .|.. ...|..|| ..| .. ....| | ... ....||. |||| |.|||||..|.. .| .|. | ..|....|..|| |||| | .||
redlerlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtpsQy
EFIHK
.|...
rflyy
|
|||||||||
0049260 | (Phosphotyrosine protein) phosphatases II | 158-350 | 4.8e-44 | 145.0 | In-house | 1-143 (152) | alignment | ||
Range on Protein: 158-350
Range on HMM: 1-143/152.0
FIGGLNSPKDYIATQGPIPAAFPDFWRMIWEYNVPTIIMVTNLKEDDKIKCHQYWpsfgaanygsfqvtlkevetvadyairtfqlqslhgqgpikevrQ
|| | . |. .|||||| | ..|||||..|... ||.|.|.| |..|.||.||. |
fidgyampfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi............................................q
YHFLVWPDHGVPQYATPLLSFQKRVRNHHKGKPGPMVVHCSAGVGRTGTFITIDTMImkidaeGIVDIFNFVRGMRFCRNYMVQTASQYDFLH
|..| |||||||. . || . . .. . . | || .||||||||||||.. .. |. |.....|. .| .|...|.. .|. ||.
ylhlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpgqlrfly
|
|||||||||
subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 122-358 | 1.9e-43 | 143.7 | In-house | 39-278 (307) | alignment | ||
Range on Protein: 122-358
Range on HMM: 39-278/307.0
PINHGKNRYVNIIPYDHSRVTLKPDGNpGSDYINASFIGGLNSPKDYIATQGPIPAAFPDFWRMIWEYNVPTIIMVTNLKEDDKIKCHQYWPSFGA--AN
| |||| .. |..|. .| || |||| | ..| || .|..||| .. .|| |. . .| ..||. .. | ||||.||||
santdknryqdvkcqdkgrivvkfdgl.asdyihanylgiaikpkkficaqgplentqysfwamaiqekvesvimlckvielakikceqywpleegqklv
YGSFQVTL----KEVETVA--DYAIRTFQLQSLHGQGpIKEVRQYHFLVWPDHGVPQYATPLLSFQKRVRnhhkGKPGPMVVHCSAGVGRTGTFITIDTM
.|. |. ....| . | .|. .|. . .... . |||.|||| . . . || .. |.||||||||||.|| ..| .
fgeapntisvanlgakklapdedlinvttlkvdwaqk.srtiqhlqwenwpdrgvpqinltainlleavr....ydtnpvvvhcsaGvGrsGtivaislv
IMK-IDAEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAIM
| |. . |. ..|. .| |.| .|| || .|| .|| .
qdkmiaGinckdmkklveelrsqrhyaiqteaqylylhrvlleyfl
|
|||||||||
subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 124-355 | 2.7e-43 | 142.9 | In-house | 33-257 (267) | alignment | ||
Range on Protein: 124-355
Range on HMM: 33-257/267.0
NHGKNRYVNIIPYDHSRVTLKPDGNPgsdYINASFIGGLNSPKDYIATQGPIPAAFPDFWRMIWEYNVPTIIMVTNLKEDDkIKchQYWPSF-G-AANYG
|. .||. . .|||..|| |. . |||||.. | . . .|.||.|. . ||. .| ...||.|...|. .|. |. ..|| | | .|
nqernrlddnlpyddtrvilrtkeee...yinasyvegyktknafivtqdplkntitdfltvihdqkvpvivlltkvftdn.ir..lfwPPkmgqakkyq
SFQVTLKEVETVADYAIRTFQLQSLhgQGPIKEVRQYHFLVWPDH-GVPQYATPLLSFQKrvRNHHKGKPGPMVVHCSAGVGRTGTFITIDTMIMKIDAE
. | . || | |..|. . ..| |.. | | ||. .|. . |.||.||.||||.|||..||... .. |
dltvehslekeendyqiitlelkfk..nesahnvtlyyykkwnintnnkpylkplfgila..knqlengnrPlvvacsdGvGrsGtflvidsqlerakte
GIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILE
|..|||.|.| .| | .|.| .| ..|. . |
gvsdifdflrkirsqriglvdtkeryiyihellae
|
|||||||||
subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 125-355 | 7.3e-43 | 141.3 | In-house | 57-281 (290) | alignment | ||
Range on Protein: 125-355
Range on HMM: 57-281/290.0
HGKNRYVNIIPYDHSRVTLKpDGNPGsDYINASFIGGLNSPkdYIATQGPIPAAFPDFWRMIWEYNVPTIIMVTNLKEDDKIKCHQYWPSFG--AANYGS
|||| ... | .|| || || .| ||. | .. ||... .| |||.. .. |.|||. . .| .|.|. .| || | ||.||.| . .|.
fkknrykdvvcndktrvilk.dGydG.dyvhanyvkGlkam..filtqGalkdtvidiwrmvlqekvaaivmlceliedGkakceqyypekeGevltfGe
FQVTLKEVETVADYA-IRTFQLQSlHGQGPIKEVRQYHFLVWPDHGVPQYATPLLSFQKRVRNhhkgKPGPMVVHCSAGVGRTGTFITIDTMIMKIDAEG
. |. | .. . .|. .. .| . .. .. |||. |.. . || . .|. .||.|||||||.||||||..|.. . .
itvlcseeddkdaniikktlsvrd.kdsGkehklkhlkikswpdksvalstlallrtlrilrk....asGpvvvhcsaGiGrtGtfvaievglqilldGk
IVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILE
.|. . || .| .| || || | ...|.
eldlldlvralrnsrlnsvqvdiqylalveilld
|
|||||||||
subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 415-649 | 7.7e-43 | 141.3 | In-house | 7-238 (239) | alignment | ||
Range on Protein: 415-649
Range on HMM: 7-238/239.0
NLAKSRVKEHLPPNDYRVVLSTKN--YDSDYICASYVDGYRQ-RSAFIATQGPMKNTAGDFWRMVWEMKSMIIIMLTNTEENGEEQSVQYWPvnpNEEDM
| || | . . . |||| . |||| |||. | |.||||| .. ..||||||.|. . .|.||| | ... |||| .
nkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywp...dstsk
YGSFNVvALPEERALPDYIVRKFKLSHSKNPdDSRTITHFQYINWPSTSCPKEATSMIDLVADVVRiQRKSGNGPITVHCSDGLGRTGTFCAMFTVLERL
| . | .| . . |||.| | .|. . . | . .... || |. ||... | . . . | | .||| |.||||.| . ..| .
ycnlrv.tlrktevfadyiirtfvmsqvgqt.eeryvyqyhftvwpdkgvpqyatavlglrrkitk.dslpgarpwvihcsagvgrtgaflvidamlrqa
KAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALE
| .. .|.| ||..| .|| .|. .|| ||| | ||
kkqktvdifnyvkairedrphmvqtseqyvfihlavle
|
|||||||||
subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 415-649 | 1e-42 | 140.9 | In-house | 8-239 (239) | alignment | ||
Range on Protein: 415-649
Range on HMM: 8-239/239.0
NLAKSRVKEHLPPNDYRVVLSTKN--YDSDYICASYVDGYRQ-RSAFIATQGPMKNTAGDFWRMVWEMKSMIIIMLTNTEENGEEQSVQYWPvnpNEEDM
| || | . . . |||| . |||| |||. | |.||||| .. ..||||||.|. . .|.||| | ... |||| .
nkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywp...dstsk
YGSFNVvALPEERALPDYIVRKFKLSHSKNPdDSRTITHFQYINWPSTSCPKEATSMIDLVADVVRiQRKSGNGPITVHCSDGLGRTGTFCAMFTVLERL
| . | .| . . |||.| | .|. . . | . .... || |. ||... | . . . | | .||| |.||||.| . ..| .
ycnlrv.tlrktevfadyiirtfvmsqvgqt.eeryvyqyhftvwpdkgvpqyatavlglrrkitk.dslpgarpwvihcsagvgrtgaflvidamlrqa
KAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALE
| .. .|.| ||..| .|| .|. .|| ||| | ||
kkqktvdifnyvkairedrphmvqtseqyvfihlavle
|
|||||||||
0041856 | (Phosphotyrosine protein) phosphatases II | 415-651 | 1.3e-42 | 140.8 | In-house | 1-171 (182) | alignment | ||
Range on Protein: 415-651
Range on HMM: 1-171/182.0
NLAKSRVKEHLPPNDYRvvlstknyDSDYICASYVDGYRQRSAFIATQGPMKNTAGDFWRMVWEMKSMIIIMLTnteengeeqSVQYWPvnpneedmygs
|| | |... ||.. | |.||| |....|.. . |||||||...| ||.||..|.. .|..|| ...|||
nldknrysdilpydhsr........dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt.........eelywp...........
fnvvalpeeralpdyivrkfklshsknPDDSRTITHFQYINWPSTSCPKeatsmIDLVADVVRIQRKsGNGPITVHCSDGLGRTGTFCAMFTVLERlkae
. |......|..|| ..| .| . | ... .. .||. |||| |.|||||..|.. ....
...........................ellerlgiqylylpwpDhgvpd.....ldelldfieevle.eggpvlVHCsaGvgRtgtlvaaylmkkl....
QvIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFV
. ......||..| .||| | .|| |.. |.||..
g.vsleeavklvrsrRpgmvitpnqyfflqlallell
|
|||||||||
subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 400-649 | 3.3e-42 | 139.3 | In-house | 30-234 (392) | alignment | ||
Range on Protein: 400-649
Range on HMM: 30-234/392.0
PTDDDFDCSIAQLSDNLAKSRVKEHLPPNDYRVVL--STKNYDSDYICASYVDGYRQRSAFIATQGPMKNTAGDFWRMVWEMKSMIIIMLTNTEENGeeq
| | .. ..|| .|| | | |. || . ||.| ||||. |||.... . |.||.||| . ||||||.. . |.|.|. .|
pgpdiypqtvaqkeinlkknryknilpydsarvkleviddipdsdylnasyipsfdnekayiasqgpnaaslddfwrmvfqenvttiamvtklkegd...
svqywpvnpneedmygsfnvvalpeeralpdyivrkfklshskNPDDSRTITHFQYINWPSTSCPKEATSMIDLVADvVRIQRKSGNGPITVHCSDGLGR
. || ||.. |.. .|| || ..|.. .. . |... . |. .||| |.||
...........................................kgddartvaqfhftewPdkdvpkhtssllkfike.vkadfGqythpliihcsagvgr
TGTFCAMFTVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALE
|| .. .|. . | ...||| | .| .|| .|. .|| ||. | ||
tgvvisidsvvahakktrmvdvfnfvtnirrkrpymvqtkeqyafiygavle
|
|||||||||
subfamily_ptpA1_pd | Subfamily ptpA1 | 124-318 | 8.9e-42 | 138.3 | In-house | 47-257 (418) | alignment | ||
Range on Protein: 124-318
Range on HMM: 47-257/418.0
NHGKNRYVNIIPYDHSRVTLKP-DGNPGSDYINASFIGGlNSPKDYIATQGPIPAAFPDFWRMIWEYNVPTIIMVTNLKEDDKIKCHQYWPS--------
| |||| ||.| .|.|| || . . ||||||| .| | ||..|.||||.| . |||||.|| . |.|.. |. .||| .|||
ntsknrytnilpvnhtrvqlkkiqdkegsdyinanyidg.aypkqfictqgplpntiadfwrmvwenrcriivmlsresencrikcdrywpeqiggeqfs
-FG--AANYGSFQVTLKEVETVADYAIRTFQLQsLHGQGPIKEVRQYHFLVWPDHGVPQYATPLLSFQKRVRNHHK------GKPGPMVVHCSAGVGRTG
.| .|.. | | || . | | ... | .| ... ||.. |||| .|... |. . . . |... . |..|||||||||||
iygngnevfgtysvelveviqdpereiitrnir.ltfegetrditqyqyegwpdhnipdhtqpfrqllhsitnrqnqiipssdrnvpiivhcsagvgrtg
TFITIDTMIMKID
|| | |. |.|
tfctavimmkkld
|
|||||||||
subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 402-655 | 1.2e-40 | 134.0 | In-house | 43-287 (290) | alignment | ||
Range on Protein: 402-655
Range on HMM: 43-287/290.0
DDDFDCSIAQLSDNLAKSRVKEhLPPNDYRVVLSTKNYDSDYICASYVDGYRqrSAFIATQGPMKNTAGDFWRMVWEMKSMIIIMLTNTEENGEEQSVQY
. .. .| . .. | | |. .. || |. || ||. | ||.| . . || |||..|.|. |.|||| . | |.|| . |.| . ||
vqylerkifdkntefkknrykd.vvcndktrvilkdGydGdyvhanyvkGlk..amfiltqGalkdtvidiwrmvlqekvaaivmlceliedGkakceqy
WPVNPNEEDMYGSFNVVALPEERALPDYIVRKFKLsHSKNPDDSRTITHFQYINWPSTSCPKEATSMIDlvadVVRIQRKSgNGPITVHCSDGLGRTGTF
.| . | .|.. |. |. . | . . . |. . . |.. . || | .. . ... ..|| || .||..|||| |.||||||
ypekeGevltfGeitvlcseeddkdaniikktlsv.rdkdsGkehklkhlkikswpdksvalstlallr....tlrilrka.sGpvvvhcsaGiGrtGtf
CAMFTVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFVNTFD
|. . |. | . .|. .|..|| | . |. || . .. |.. |.
vaievglqilldGkeldlldlvralrnsrlnsvqvdiqylalveilldlGkdfk
|
|||||||||
0043147 | (Phosphotyrosine protein) phosphatases II | 440-645 | 2.1e-40 | 133.6 | In-house | 4-155 (172) | alignment | ||
Range on Protein: 440-645
Range on HMM: 4-155/172.0
DSDYICASYVDGYRQRSAFIATQGPMKNTAGDFWRMVWEMKSMIIIMLTNTeengeeqsvqywpvnpneedmygsfnvvalpeeralpdyivrkfklsHS
.|||| |||.|.|. |||||||. || |||||..|.. .|..||.
gsdyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltel...............................................ly
KNPDDSRTITHFQYINWPSTSCPkEATSMIDLVADVVRIQRKSGNGPITVHCSDGLGRTGTFCAMFTVLerlkaeQVIDVFSTVKTLRIQRPGFVNDIDQ
.. .|.. ...|..|| ..| . ..... . ... .| .||. |||| |.|||||..|.. .| . .... .|...| .||| | .|
dpellerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml......lglsleeavalvrekRpgavqnpsq
YEFIHK
| |...
yrflyy
|
|||||||||
0049772 | (Phosphotyrosine protein) phosphatases II | 407-654 | 2.2e-40 | 134.7 | In-house | 38-283 (314) | alignment | ||
Range on Protein: 407-654
Range on HMM: 38-283/314.0
CSIAQLSDNLAKSRVKEHLPPNDYRVVLSTKNYDSDYICASYVDGYrqrSAFIATQGPMKNTAGDF----------WRMV--WEMKSMIIIM--------
. .|.| | | | .. || . .... . ...|||| ||||||. .|||||||...| || |||| ..... .| |
ilvadlflnrdknryldilpadnrvilpglpvsgsdyinasyvdgf...lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivmsrdevlad
-------------LTNTEENGeeqsvqywpvnpneedmY----------GsfnvvalpEERALPDYIvrkfklshsknpddSRTITHFQYINWPSTSCPk
|.. .|| || |.. .|.. .. .|..| |.|
elsrLdaAlgKtpllildgng.................neptaadlellk........eelydpelf..............erlgikylripvpDgsap.
EATSMIDLVADVVRIqrkSGNGPITVHCSDGLGRTGTFCAMFTVLERLKaeqViDVFSTVKTLRIQRP-----GFVNDIDQYEFIHKAALEFVNTF
. .... . . . .||. |||..| ||||||... .. .|. | .. ... .| .|| ||.. .|||||..| ||.....
lledfdeflefieea...dkggpvlvHCkaGkgRtgtfvvaaylmkllg...v.sleealedvrlkRpinpnpgfieqleqyefilealleylkfl
|
|||||||||
0046846 | (Phosphotyrosine protein) phosphatases II | 431-650 | 3.4e-39 | 129.7 | In-house | 2-172 (176) | alignment | ||
Range on Protein: 431-650
Range on HMM: 2-172/176.0
RVVLSTKNYDSDYICASYVDGYRqrsaFIATQGPMKNTAGDFWRMVWEMKSMIIIMLTNTEENGEEQSVQYWPVnP-NEEDmygsfnvvalpeeralpdy
|..|.. ..|.||| |....|.| .||||||. .| ||..|..|.. ....||. | | . .|||. ...
rlrllgldldldyinanlilgsr....piatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpe.leklgi...................
ivrkfklshsknpddsrtitHFQYINWPSTSCPKEaTSMIDLVADVVRIQRKSgnGPITVHCSDGLGRTGTFCAMFtvleRLKAEQVIDVFSTVKTLRIQ
......|| ..| . ...|.. . . ... ||. |||| |.|||||..|.. |. |. ..|. .....| |
....................qylhlpwpDhgvpdl.elllellefirealkeg..gpvlVHCsaGigRtgtlvaay....llelekglsveealalvreq
RP-GFVNDIDQYEFIHKAALEF
|| | | .||.|.....|..
RplgavqtpeQyrflyefelll
|
|||||||||
0051082 | (Phosphotyrosine protein) phosphatases II | 150-354 | 9.3e-38 | 124.5 | In-house | 2-150 (151) | alignment | ||
Range on Protein: 150-354
Range on HMM: 2-150/151.0
GSDYINASFIGGLnspkdYIATQGPipaaFPDFWRMIWEYNVPTIIMVTNLKEDDkiKCHQYWPSFGaanygsfqvtlkevetvadyairtfqlqslhgq
|||||.|...| .....|| .||.....|... ||.......| . .|..|.|. |
lsdyinfsyvtgg.....lyrsggp....ladflellkelgiktivnlrseeerg..ycpeylpelg.................................
gpiKEVRQYHFLVWPDHGVPQYATPLLSFQKRVRNhhkGKPGPMVVHCSAGVGRTGTFITIDTMIMKidaegiVDIFNFVRGMRFCRNYMVQTASQYDFL
||.....| |||.|.|.. .|.| . ... |.||..||||||.|||||.. .. |... |... .. .| .| ..||. |. |.
...ievlhipildwpdpglplsfdavleflellld...kkngpvlvHCsaGkgRTGtlvalylmllg......vsleealeeyrlkrpgvvqpnqqflfq
HHAIL
..|.|
lfall
|
|||||||||
subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 409-651 | 1.2e-37 | 124.6 | In-house | 35-277 (307) | alignment | ||
Range on Protein: 409-651
Range on HMM: 35-277/307.0
IAQLSDNLAKSRVKEHLPPNDYRVVLSTKNYDSDYICASYVDGYRQRSAFIATQGPMKNTAGDFWRMVWEMKSMIIIMLTNTEENGEEQSVQYWPVNPNE
. .| | | | .. . |.|. .. |||| | |. . ||..|||..|| .|| |. . | .||| .. | .. . ||||.. .
veafsantdknryqdvkcqdkgrivvkfdglasdyihanylgiaikpkkficaqgplentqysfwamaiqekvesvimlckvielakikceqywpleegq
EDMYGS----FNVVALPEERALPDYIVRKFKLSHSKNPDDSRTITHFQYINWPSTSCPKEATSMIDLVADVvriqrKSGNGPITVHCSDGLGRTGTFCAM
. ..|. .| | .. || . . . . ..||||.|.|. ||| .|. . |.|. | . . |. |||| |.||.|| |.
klvfgeapntisvanlgakklapdedlinvttlkvdwaqksrtiqhlqwenwpdrgvpqinltainlleav.....rydtnpvvvhcsaGvGrsGtivai
FTVLERL-KAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFV
| ... . . |. |. || ||. ... || ..|. ||.
slvqdkmiaGinckdmkklveelrsqrhyaiqteaqylylhrvlleyf
|
|||||||||
0049260 | (Phosphotyrosine protein) phosphatases II | 448-645 | 1.8e-37 | 123.7 | In-house | 1-144 (152) | alignment | ||
Range on Protein: 448-645
Range on HMM: 1-144/152.0
YVDGYRQRSAFIATQGPMKNTAGDFWRMVWEMKSMIIIMLTNTEENGEEQSVQYWpvnpneedmygsfnvvalpeeralpdyivrkfklshsknpddsrt
..|||.. .|||||||. ||. |||||..|.. .|.|||. .|.|... ||.
fidgyampfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi.............................................
itHFQYINWPSTSCPKEATSMIDLVADVVRIqRKSGNGPITVHCSDGLGRTGTFCAMFTVLerlkaeQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHK
......|| ..|. . ...|. . .. ... .||. |||| |.|||||..|.. .| . .... .|. .| .||| | .|..|...
..qylhlpwpDhgvpdlsqlllflllfiekl.aldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpgqlrflye
|
|||||||||
0044763 | (Phosphotyrosine protein) phosphatases II | 135-354 | 2.9e-37 | 123.4 | In-house | 1-168 (178) | alignment | ||
Range on Protein: 135-354
Range on HMM: 1-168/178.0
PYDHSRVTLKP-DGNPGSDYINASFIGglnsPKDYIATQGPipaafPDFWRMIWEYNVPTIIMVTNLKEDDKIKCHQYWPSFGAanygsfqvtlkevetv
|.|..|| | . | ..|||||||.| | |.....| .|......|... .|...|. .| ..||..|||.
pldrtrvllsnleglersdyinaseil....pglylgslpp.....addlellkelgithivnlteelelgflkcdpywpeeag................
adyairtfqlqslhgqgpikevRQYHFLVWPDHGVPQYATPLLSFQKRVRNHHKGKPGPMVVHCSAGVGRTGTFITIDTMIMKidaeGIvDIFNFVRGMR
||... .||||||. .| | . ...... |.|| .|||||||||.||.. .. |.. |. .... .. .|
......................iqylhipipDhgvpdllehflefvefieealdekggpvlVHCsaGvgRsgtlvaaylmkkl....gl.sleeaielvr
FCRNyMVQTASQYDFLHHAIL
.|. .|.. .|. .|. |
erRp.ivpnpgqlrqLyefel
|
|||||||||
subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 122-358 | 3.5e-37 | 122.8 | In-house | 46-288 (305) | alignment | ||
Range on Protein: 122-358
Range on HMM: 46-288/305.0
PINHGKNRYVNIIPYDHSRVTLkpDGNPGSDYINASFIGGLNSPKDYIATQGPIPAAFPDFWRMIWEYNVPTIIMVTNLKEDDKIKCHQYWPSFGAAN--
..||||| .. |. || | .| .|| | .. || .| || |. . ||| | .. .| .|.|. ||.| ||..|..|
aqeagknrykdvgcldnnrvkl..egpwpheyihanyvstptnpkrfictqaplektcadfwymclqdkveaifmlcnllekgakkcleyfaskdkdvle
--YGSFQVTLKEvETVADYA--------IRTFQLqSLHGQGP-IKEVRQYHFLVWPDHGVPQYATPLLSFQKRVRNHHkgkpGPMVVHCSAGVGRTGTFI
. ....| |. . . .. .| . | | . | .||. ||| ||| . .| . .. | . ||.|||||||.||||. .
feekgqkisvkf.essvtlkfrkdakakvtetvl.viegpgekarkvthyhwidwpdrgvpaadlailellekarpsk....gpivvhcsagigrtgsvv
TIDTMIMKIDAEGIV-DIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAIM
.. .. .. | |. | .. .| || .|| || |.| ||. .
mleyildqllagqiiedtdkilqkireqrnnsiqtdaqylfvhqvilnyfr
|
|||||||||
PTPc_DSPc_SM00012 | 255-355 | 7.8e-36 | 117.8 | In-house | 2-105 (105) | alignment | |||
Range on Protein: 255-355
Range on HMM: 2-105/105.0
VRQYHFLVWPDHGVPQYATPLLSFQKRVRNHHKGKP--GPMVVHCSAGVGRTGTFITIDTMIMKIDAE-GIVDIFNFVRGMRFCRNYMVQTASQYDFLHH
|..||.. |||||||......|.. . |..... . .|.||||||||||||||...|........| . ||||..|. .| |. |||| || ||..
vkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylflyr
AILE
|.||
alle
|
|||||||||
subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 122-357 | 2.9e-35 | 116.4 | In-house | 53-289 (305) | alignment | ||
Range on Protein: 122-357
Range on HMM: 53-289/305.0
PINHGKNRYVNIIPYDHSRVTLKpdGNPGSDYINASFIGGLNSP-KDYIATQGPIPAAFPDFWRMIWEYNVPTIIMVTNLKEDDKIKCHQYWPSFGAAN-
|. |||| .. |.| | |. . |||| | ..| | | .|..|||. . .|| |. . .| |.|. . | |.|| |||| .
diaitknryqdvpcqdqsavkld..kpspsdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkveqivmlcktvelgklkcaqywpaaqgekl
YGSFQVTL------KEVETVADYAIRTfqLQSLHGQGPIKEVRQYHFLVWPDHGVPQYATPLLSFQKRVRnhhkGKPGPMVVHCSAGVGRTGTFITIDTM
. . | .| |. | . |. . . ||. .. ||| ||| | . .| | |.|||||||.||||| ..|. .
elksgivvenvsgskpmerdaeiqitl..lnltysgdqkmsvrhlqwtewpdrgvppckltslellsair....gskvpivvhcsagigrtgtivaieyi
IMKIDA-EGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAI
. || . ..|. .| | . .|. || |.| .|. .
lekiaenkpcppmpelvkalrdqrafsiqndvqylfihrvmlnyf
|
|||||||||
subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 120-355 | 1.4e-34 | 114.1 | In-house | 33-267 (281) | alignment | ||
Range on Protein: 120-355
Range on HMM: 33-267/281.0
KLPINHGKNRYVNIIPYDHSRVTLKP--DGNPGSDYINASFIGGLNSPKDYIATQGPIPAAFPDFWRMIWEYNVPTIIMVTNLKEDDKIKCHQYWPSFGA
. |.| ||||.|| | ||| || . .||| | .| . || |||| . |||||||. | .|.|. .. | .. || .|.|
nqpvnnkknrylnipcldisrvqlkvkmpnknstdyihanyirspflkrgyiltqgpkketradfwrmiwqenttaivmlcqfletnrekcaeyfprnah
--ANYGSFQVTLkEVETVADyAIRTFQLQsLHGQGPIKEVRQYHFLVWPDHGVPQYATPLLSFQKRVRNhhkgKPGPMVVHCSAGVGRTGTFITIDTMIM
.. . |. | || .. | .|. | .| . . .. . ||| ||. . .| ...| . | |.||||||||.||..... .
cclqfdklsvsy.edstvnk.slvttrln.lsyegetrlithwlwkewpdwqvpessevmlkilrkira....rstppvihcsagvgrsgtlmaveialq
KIDAE-GIVDIFNFVRGMRF-CRNYMVQTASQYDFLHHAILE
| . . || . | .| | ||| || .. . .|.
sihshftlpdikqivshlrvtgraasvqtlqqymliwkvlld
|
|||||||||
subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 399-639 | 4.2e-34 | 112.7 | In-house | 36-269 (301) | alignment | ||
Range on Protein: 399-639
Range on HMM: 36-269/301.0
SPTDDDFDCSIAQLSDNlaKSRVKeHLPPNDYRVVLSTKNYDSDYICASYVDGYRQRSAFIATQGPMKNTAGDFWRMVWEMKSMIIIMLTNTEENGEEQS
. |. . | | | .. | | . ..| . | .. | | ... . |||||||.|||. ||| |. . |.||... |. ||.
tidkdhitesyaylpkd..khryp.tvPckPstavevivdGkrvPihanwiptsGhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekc
VQYWPVNPNEEDMYGSFNVVALPEERALPDYIV-RKFKLSHSKNPDDSRTITHFQYINWPSTSCPKEATSMIDLVadvvRIQRKSgNGPITVHCSDGLGR
.| ||...|. | |.. .| | . |. |.... | . ..||.||.|| .|. || . . ||. . .|| . || ||||.|.||
eeylpvkisekldigrfkikiknkelilnkkiskrtlevedstgkfatrtvthyqysewtdrgvPkshaelfdlm....elvkks.ekPivvhcsaGiGr
TGTFCAMFTVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQ
. .| . . ...|.. |.. ..| || .| |. |
svafigteylareveadptieltealkhlrehrwngvqtnsq
|
|||||||||
subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 122-358 | 5.1e-34 | 112.5 | In-house | 33-271 (285) | alignment | ||
Range on Protein: 122-358
Range on HMM: 33-271/285.0
PINHGKNRYVNIIPYDHSRVTLKpdgNPGSDYINASFIGGL-NSPKDYIATQGPIPAAFPDFWRMIWEYNVPTIIMVTNLKEDDKIKCHQYWPS-FG-AA
| ||| .. . .|| || | ||| ||.. . ||.||||.| .. |||.||.. .. ..|. | | || |.| .|
eanpdlnryadvrcieetrvvlk...nhdrdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyypeklgevv
NYGSFQVTLKEVE--TVADYAIRTFQLQslHGQGPIKE---VRQYHFLVWPDHGVPQYATPLLSFQKRVRNHhKGKPGPMVVHCSAGVGRTGTFITIDTM
..| ...|| |.. ..| . .. . . | . . . |||. |. | |.. . | |.. . | |..|||||||||| ||. ||
kfgkyeitlteckeeaiagtilnaltvi..ntedasseplymnhvqvpwwpdqlapedarpmielykwvkkv.npkekpicvhcsagvgrtatfvgidya
IMKIDAEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAIM
..| . ..... || || | ||. |. ||. ..| ..
tirimenpniemldivremramrfqavqshmqflflyvvlmeyfi
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 119-282 | 7.7e-34 | 111.9 | In-house | 28-193 (297) | alignment | ||
Range on Protein: 119-282
Range on HMM: 28-193/297.0
AKLPINHGKNRYVNIIPYDHSRVTLKpDGNPGSDYINASFIGGLNSPKD--YIATQGPIPAAFPDFWRMIWEYNVPTIIMVTNLKEDDKIKCHQYWPSFG
|| . |||| .|. .| .|| |. . ...||||| .. . ..| || .|||. |. |||....| .| .|.||..|.|| . || ||||
akrnsslrknryrdilatddtrvkll.rviterdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrdkcapywpsvv
AANYGSFQVTLKEVETVAD-YA-IRTFQLQSLHGqGPIKEVRQYHFLVWPDHGVPQYATPLLSFQKRV
. . .| .. . ...| . . .|| .. . || || ||||||| | || .|
qerlkagdvvveflsstsdefdrviltelqliyr.sesrvvrhvqflswpdhGvpsdledlvrfqaqv
|
|||||||||
subfamily_ptpA1_pd | Subfamily ptpA1 | 407-611 | 1e-32 | 108.4 | In-house | 39-256 (418) | alignment | ||
Range on Protein: 407-611
Range on HMM: 39-256/418.0
CSIAQLSDNLAKSRVKEHLPPNDYRVVLST--KNYDSDYICASYVDGYRQRsAFIATQGPMKNTAGDFWRMVWEMKSMIIIMLTNTEENGEEQSVQYWPV
| . | .| | . || | || | . |||| | |.|| . ||.||||. || |||||||| . ||.||. || . .|||
tsegdkkhntsknrytnilpvnhtrvqlkkiqdkegsdyinanyidgaypk.qfictqgplpntiadfwrmvwenrcriivmlsresencrikcdrywpe
NPNEE--DMYGSFNV------VALPEERALP--DYIVRKFKLSHSknpDDSRTITHFQYINWPSTSCPKEATSMIDLVADVVRIQR-----KSGNGPITV
. | .|| | | | | | . | |. .|. ..| ||..|| || | . . .|. . | | || |
qiggeqfsiygngnevfgtysvelveviqdpereiitrnirltfe...getrditqyqyegwpdhnipdhtqpfrqllhsitnrqnqiipssdrnvpiiv
HCSDGLGRTGTFCAMFTVLERL
||| |.|||||||. ....|
hcsagvgrtgtfctavimmkkl
|
|||||||||
subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 126-348 | 6.9e-32 | 105.4 | In-house | 52-272 (301) | alignment | ||
Range on Protein: 126-348
Range on HMM: 52-272/301.0
GKNRYVNIIPYDHSRVTLKPDGNpgSDYINASFIGGLNSPKDYIATQGPIPAAFPDFWRMIWEYNVPTIIMVTNLKEDDKIKCHQYWPSFGAA--NYGSF
|.|| .. .. | . ||. | | .| |. .||||||.... ||| |. |.| .|.|... |. . ||..| |. . . | |
dkhryptvPckPstavevivdGk..rvPihanwiptsGhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkisekldigrf
QVTLKEVETVADYAI--RTFQLQSLHGQGPIKEVRQYHFLVWPDHGVPQYATPLLSFQKRVRNHHKgkpgPMVVHCSAGVGRTGTFITIDTMIMKIDAEG
....|. |.. . | ||.... |. . . | | . |.|.|||. . | . . |.. .| |.|||||||.||. .||. . . ...|.
kikiknkelilnkkiskrtlevedstgkfatrtvthyqysewtdrgvPkshaelfdlmelvkksek....PivvhcsaGiGrsvafigteylareveadp
IVDIFNFVRGMRFCRNYMVQTASQYDF
... . .. .| | ||| || .
tieltealkhlrehrwngvqtnsqlyw
|
|||||||||
subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 415-651 | 9.5e-32 | 104.8 | In-house | 53-289 (305) | alignment | ||
Range on Protein: 415-651
Range on HMM: 53-289/305.0
NL--AKSRVkEHLPPNDYRVVLSTKNYDSDYICASYVDGYR-QRSAFIATQGPMKNTAGDFWRMVWEMKSMIIIMLTNTEENGEEQSVQYWPVNPNEEDM
.. .| | . .| .| .|. | |||| | || ||..|||. .| .|| || . | |.|| .| | | . ||||. |
diaitknry.qdvpcqdqsavkldkpspsdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkveqivmlcktvelgklkcaqywpaaqgekle
YGSFNVVA-----LPEERAlPDYIVRKFKLSHSknPDDSRTITHFQYINWPSTSCPKEATSMIDLVADVvriqrKSGNGPITVHCSDGLGRTGTFCAMFT
| || | || .. . ..|..| |.. .. |.|. .|| | . ..|.. . . . || |||| |.||||| |.
lksgivvenvsgskpmerd.aeiqitllnltys..gdqkmsvrhlqwtewpdrgvppckltslellsai.....rgskvpivvhcsagigrtgtivaiey
VLERLKAE-QVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFV
.||.. . .. . ||.|| || ... || |||. |...
ilekiaenkpcppmpelvkalrdqrafsiqndvqylfihrvmlnyf
|
|||||||||
0051082 | (Phosphotyrosine protein) phosphatases II | 441-647 | 1.4e-31 | 104.5 | In-house | 3-149 (151) | alignment | ||
Range on Protein: 441-647
Range on HMM: 3-149/151.0
SDYICASYVDGYrqrsaFIATQGPMKntagDFWRMVWEMKSMIIIMLTNTEENGeeQSVQYWPVNPneedmygsfnvvalpeeralpdyivrkfklshsk
|||| .|||.|. .....||. ||.....|.. |..|...||.| .|.| .
sdyinfsyvtgg.....lyrsggpla....dflellkelgiktivnlrseeerg..ycpeylpelg..................................
npddsRTITHFQYINWPSTScpkeATSMIDLVADVVRIQRKSGNGPITVHCSDGLGRTGTFCAMFTVLERlkaeqvIDVFSTVKTLRIQRPGFVNDIDQY
....|.....|| .. ..| |...... .. .|||. |||| |.|||||..|.. .|.. ........ .|..|||.|. .|.
.....ievlhipildwpdpg....lplsfdavleflellldkkngpvlvHCsaGkgRTGtlvalylmllg......vsleealeeyrlkrpgvvqpnqqf
EFIHKAA
|...|
lfqlfal
|
|||||||||
subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 101-360 | 3e-31 | 103.5 | In-house | 21-274 (288) | alignment | ||
Range on Protein: 101-360
Range on HMM: 21-274/288.0
LEEEYPDIELEWNFTSyAAKLPINHGKNRYVNIIPYDHSRVTLKPDGnpgSDYINASFIGGLNSPKDYIATQGPIPAAFPDFWRMIWEYNVPTIIMVTNL
|. || | | . . . . | ..|| |. | .|| |. | ||.| . . .. | .| |. .. .|.|. | .| |.|...|
lkkeyrdspneasidi.idsfianptrdryenlprcditrvklsddp...dfyiaanvvssakykrrlicaqaPlngtieelWkmllesdveyivmlcel
KEDDKIKCHQYWPSF-G-AANYGSFQVTLKEVETVADyaiRTFQLQSLHGQGPI--KE-VRQYHFLVWPDHGVPQYATPLLSFQKRVRNHHKgkpgPMVV
| | | .|.|| | .| .| . |. . | .. .. |. . .. | |.. |.| |.|.|||. . | . .......| |.||
lekGkeksaeyfPsklGekarigrlctvvkkkradid...klvkvsllriskegeekvivkilhlleWdddgvPenylsplrllevlkslqk....Pivv
HCSAGVGRTGTFITIDTMIMKIDAEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAIMCR
|.|||||||||.| | .. . . . | ... .| | .|| || ..| .|| .. .
hssaGvGrtgtlililialeslrlddflgirsllaklreerfkaiqtemqylyvhrcvleelllk
|
|||||||||
subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 455-645 | 3.2e-31 | 103.1 | In-house | 4-198 (199) | alignment | ||
Range on Protein: 455-645
Range on HMM: 4-198/199.0
RSAFIATQGPMKNTAGDFWRMVWEMKSMIIIMLTNTEENGEEQSVQYWPVNPNEEDMYGSFNVVALpEERALPDYIVRKFKLSH-SKNPDDSRTITHFQY
. .|||| |...| |||.|||| | |.|. . . | | . |||. . |||..|.. . ||| . . |. . | .| |.|.|.
qrryiatqhplretmadfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttk.tittkpdytitaliltnnttappstreishyqf
INWPSTSCPKEATSMIDLVA--DVVRIQRKSGNGPITVHCSDGLGRTGTFCAMFTVLERL--KAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHK
| . |. | . .|| .| . . . |. |||||| | || | |. . |.|.| | || | | . ...|.||..
tswkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiyq
|
|||||||||
subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 456-645 | 3.5e-31 | 102.9 | In-house | 4-197 (198) | alignment | ||
Range on Protein: 456-645
Range on HMM: 4-197/198.0
SAFIATQGPMKNTAGDFWRMVWEMKSMIIIMLTNTEENGEEQSVQYWPVNPNEEDMYGSFNVVALpEERALPDYIVRKFKLSH-SKNPDDSRTITHFQYI
.|||| |...| |||.|||| | |.|. . . | | . |||. . |||..|.. . ||| . . |. . | .| |.|.|.
rryiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttk.tittkpdytitaliltnnttappstreishyqft
NWPSTSCPKEATSMIDLVA--DVVRIQRKSGNGPITVHCSDGLGRTGTFCAMFTVLERL--KAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHK
| . |. | . .|| .| . . . |. |||||| | || | |. . |.|.| | || | | . ...|.||..
swkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiyq
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 121-287 | 3.7e-31 | 103.0 | In-house | 24-195 (319) | alignment | ||
Range on Protein: 121-287
Range on HMM: 24-195/319.0
LPI-NHGKNRYVNIIPYDHSRVTLKPDGN-PGSDYINASFIGGLN-SPKDYIATQGPIPAAFPDFWRMIWEYNVPTIIMVTNLKEDDKIKCHQYWPSF--
.|. . |.|..|..| ..||.|. |. . . |..||.. | . .| |||.| . . ||||..|| . .|. .|.| | .| .|.|.
vPvtskdksrvinvvPlPetrvvlqrigdddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlselGikvcaeylPtket
--GAANYGSFQVTLKEVETVADYAIRTFQLQSLHGQGpIKEVRQYHFlVWPDHGVPQYATPLLSFQKRVRNHHK
. || ..||||. |. ||| |. |. .... .|. | . |.. .|| ..|.. .||. |
ldntslyGdilvtlkgrevkdryaistlllkrvdkee.srelthywy.kwleaevPaeeaaliamllevrsslk
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 254-394 | 3.7e-31 | 102.9 | In-house | 90-231 (440) | alignment | ||
Range on Protein: 254-394
Range on HMM: 90-231/440.0
EVRQYHFLVWPDHGVPQYATPLLSFQKRVRN-HHKGKPGPMVVHCSAGVGRTGTFITIDTMIMKIDAEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHA
..|||. |||.|||..| |.| . . | . ..| ||..||||||.|||| |..|... . .|||.|. || | |||| || |.|.|
tlkqyhyqgwpdkgvpkfagpvlkmiqdvnesqekagngpllvhcsagagrtgviiavdsilreakrsdqidifsfinsmrnnrpqmvqtpeqyafvhea
ILEAIMCRDTTIPAVHMATKIATLKEIAPSSGKTGFQSQFET
.||...| || | .. .. .. | . |. .| .||
vlegllcgdtliledditerveqiqwpnphtdksplqqefeg
|
|||||||||
PTPc_DSPc_SM00012 | 547-649 | 5.6e-31 | 102.2 | In-house | 1-105 (105) | alignment | |||
Range on Protein: 547-649
Range on HMM: 1-105/105.0
TITHFQYINWPSTSCPKEATSMIDLVADVVRIQRKSG-NGPITVHCSDGLGRTGTFCAMFTVLERLKAE-QVIDVFSTVKTLRIQRPGFVNDIDQYEFIH
|..|..| .|| ...|.|..|...|...| . ..||. ..|. ||||.| ||||||.|. ..|..|..| . .|.| .|| || |||| |. .|| |..
tvkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylfly
KAALE
.| ||
ralle
|
|||||||||
subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 124-354 | 5.4e-30 | 99.0 | In-house | 52-287 (310) | alignment | ||
Range on Protein: 124-354
Range on HMM: 52-287/310.0
NHGKNRYVNIIPYDHSRVTLKPDGNPGSDYINASFIGGLNSPKDYIATQGPIPAAFPDFWRMIWEYNVPTIIMVTNLKEDDKIKCHQYWPSFGAA-NYGS
. |||| ... | ||| || | ||| | .. . .| .|||. . ||||||.. .|... . |. . || ||||.| . ||
ymhknrysdvvcldtsrvklkidksryedyihanyvktnylrstficsqgplqhtiidfwrmifqeraesilllckvgeegrpkcvgywpslgvtetygc
FQVTLKeVETVADYAIRTFQLQSLHGQGPIK-------EVR--QYHFLVWPDHGVPQYATPLLSfqKRVRnhHKGKPGPMVVHCSAGVGRTGTFITIDTM
.|| |. .. | . . . . |. |.| .. ||| |||. . .|. . . || |||||||..|... ....
irvtnl.sesseefeicnlavtfvpdnvpvdeqpanlkelrvslikwpnwpdrgvpdekchtvp..qrll..aqvrhgpcvvhcsagkdrlyvvvalklk
IMKIDAEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAIL
| |.| ||. . . .. | .|| || .... .
idkldrglkvdaeevktellksraiciqtelqyliidrvri
|
|||||||||
0044763 | (Phosphotyrosine protein) phosphatases II | 429-649 | 1.6e-29 | 98.2 | In-house | 4-169 (178) | alignment | ||
Range on Protein: 429-649
Range on HMM: 4-169/178.0
DYRVVLST--KNYDSDYICASYVDGYrqrsAFIATQGPmkntaGDFWRMVWEMKSMIIIMLTNTEENGEEQSVQYWPVNPNeedmygsfnvvalpeeral
..||.||. |||| ||..... ......| |......|.. |..||.. |.| ... .||| . .
rtrvllsnleglersdyinaseilpg....lylgslpp.....addlellkelgithivnlteelelgflkcdpywpeeag...................
pdyivrkfklshsknpddsrtiTHFQYINWPSTSCPKeATSMIDLVADVVRIQRKSGNGPITVHCSDGLGRTGTFCAMFTVLERlkaeQViDVFSTVKTL
....|..| ..| ..... . . .. ... .||. |||| |.||.||..|.. .... .. .... .. .
......................iqylhipipDhgvpd.llehflefvefieealdekggpvlVHCsaGvgRsgtlvaaylmkkl....gl.sleeaielv
RIQRPgFVNDIDQYEFIHKAALE
| .|| .| .|...... .|.
rerRp.ivpnpgqlrqLyefelr
|
|||||||||
subfamily_egg_pd | Subfamily egg | 388-650 | 3.1e-29 | 96.6 | In-house | 16-269 (307) | alignment | ||
Range on Protein: 388-650
Range on HMM: 16-269/307.0
FQSQFETLESSSpTDDDFDCSiaQLSDNLAKSRVKEHLPPNDYRVVLSTK--NYDSDYICASYVDGYRQRSAFIATQGPMKNTAGDFWRMVWEMKSMIII
.. ..| || |. . . . ..|| |.| | . || | . | |.| | .|.| || .| |.||| ||||||.. . |.
lerrlevleesv.deisltta..asdnnlekarskrvhckdssrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvddfwrmvfqeevqyiv
MLTNTEENgeEQSVQYWPVNPNEEDMY--GSFNVVALP-EERALPDYIVRKFKLSHSKnpDDSRTITHFQYiNWpstscpkEATSMIDLVADVVRIQRKS
||| . |. |. ||| ... .. ||... .| ...| | . | |.|| .. |. | . |.|. .. . .| . |.| |.
mltsrkes..erceyywpkaesdslvtvpGslrienlkvdskadplfrvtklklvGgd..deerflehwqg.dv.......nnssdvysplrvlrklrnl
GNgPITVHCSDGLGRTGTFCAMFTVLERLKAEQV--IDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEF
. |. |.. .| ...|. |. . | | . | .|. || .|. |. . .| |... | |
sk.pvvvqdilGvskaatlvaieiallsllrGpitkslvlravvflrlrrrlsvesvllylfvyrlvlff
|
|||||||||
subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 415-652 | 3.7e-29 | 96.4 | In-house | 48-288 (305) | alignment | ||
Range on Protein: 415-652
Range on HMM: 48-288/305.0
NLAKSRVKEHLPPNDYRVVLsTKNYDSDYICASYVDGYRQRSAFIATQGPMKNTAGDFWRMVWEMKSMIIIMLTNTEENGEEQSVQYWPVNPNEEDMY--
. | | |. .. || | . .|| | || . || || |...| ||| | .. | |.|| | | | .. ..|.. . ... .
eagknrykdvgcldnnrvkl.egpwpheyihanyvstptnpkrfictqaplektcadfwymclqdkveaifmlcnllekgakkcleyfaskdkdvlefee
------GSFNVVALPEERALPDYIVRKFKLSHSKNPDDSRTITHFQYINWPSTSCPKEATSMIDLVADVvriqrKSGNGPITVHCSDGLGRTGTFCAMFT
|. . . |. . |.. .| ..| .||. .|.|| | .....|... .. |||.|||| |.||||. .
kgqkisvkfessvtlkfrkdakakvtetvlviegpgekarkvthyhwidwpdrgvpaadlailelleka.....rpskgpivvhcsagigrtgsvvmley
VLERLKAEQVIDVFS-TVKTLRIQRPGFVNDIDQYEFIHKAALEFVN
.|..| | |.|. .. .| || .. .|| |.|. |....
ildqllagqiiedtdkilqkireqrnnsiqtdaqylfvhqvilnyfr
|
|||||||||
subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 428-650 | 8.3e-29 | 95.4 | In-house | 48-269 (285) | alignment | ||
Range on Protein: 428-650
Range on HMM: 48-269/285.0
NDYRVVLstKNYDSDYICASYVD-GYRQRSAFIATQGPMKNTAGDFWRMVWEMKSMIIIMLTNTEENGEEQSVQYWPVNPNEEDMYGSFNVV-ALPEERA
.. |||| ||.| ||| ||.. ...|..|.||||. .| |||.|... | ..|| | | |. |.| . | .| ... . .| |
eetrvvl..knhdrdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyypeklgevvkfgkyeitlteckeea
LPDYIVRKFKLSHSKNP-DDSRTITHFQYINWPSTSCPKEATSMIDLVADVVRIQRKsgNGPITVHCSDGLGRTGTFCAMFTVLERLKAEQVIDVFSTVK
. |. . . ... . . | | || .|..| ||.| | ... | . || |||| |.||| || . |. . |... |.
iagtilnaltvintedasseplymnhvqvpwwpdqlapedarpmielykwvkkvnpk..ekpicvhcsagvgrtatfvgidyatirimenpniemldivr
TLRIQRPGFVNDIDQYEFIHKAALEF
.| | |. |. |.. .|.
emramrfqavqshmqflflyvvlmey
|
|||||||||
subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 407-654 | 1.5e-28 | 94.2 | In-house | 29-272 (281) | alignment | ||
Range on Protein: 407-654
Range on HMM: 29-272/281.0
CSIAQLSDNLAKSRVKEhLPPND-YRVVLST----KNyDSDYICASYVDGYRQRSAFIATQGPMKNTAGDFWRMVWEMKSMIIIMLTNTEENGEEQSVQY
|.. . | | | . .| | || | || .||| | |. . .| |||| |.| |||||.|. .. |.|| . | |. .|
ctvfnqpvnnkknryln.ipcldisrvqlkvkmpnkn.stdyihanyirspflkrgyiltqgpkketradfwrmiwqenttaivmlcqfletnrekcaey
WPVNPNEEDMYGSFNVVAlpEERALPDY-IVRKFKLSHSknpDDSRTITHFQYINWPSTSCPKEATSMIDLVAdvvRIQRKSgnGPITVHCSDGLGRTGT
.| | . . | |. .. . ...||. ..| |||. . .|| |. . |. .. .|. .| | .||| |.||.||
fprnahcclqfdklsvsy..edstvnkslvttrlnlsye...getrlithwlwkewpdwqvpessevmlkilr...kirars..tppvihcsagvgrsgt
FCAMFTVLERLKAEQV-IDVFSTVKTLRIQ-RPGFVNDIDQYEFIHKAALEFVNTF
. |. |. ... |. | ||. | |. ..|| .| | |.| ..
lmaveialqsihshftlpdikqivshlrvtgraasvqtlqqymliwkvlldfgvay
|
|||||||||
0048076 | (Phosphotyrosine protein) phosphatases II | 220-353 | 6.2e-28 | 92.7 | In-house | 13-139 (145) | alignment | ||
Range on Protein: 220-353
Range on HMM: 13-139/145.0
YGSFQvTLKEVETVADYAIRTFQLQSLHGQGPIKEVRQYHFLVWPDHGVPQYATPLLSFQKRVRNHHKGKpGPMVVHCSAGVGRTGTFITIDTMIMkida
.||. | ...|. .|. |.| . ... ... ||..| |||||||. . ||.| . .....| . ||..||||||||||||.. .. |..
lgslp.taldlellkdlgittvlnltselellerlgiqylylpwpDhgvpdllellleflefieealkeg.gpvlVHCsaGvgRtgtlvaaylmll....
EGiVDIFNFVRGMRFCRNYMVQTASQYDFLHHAI
.| |.... .. .| .| ..|.. .|. ||. ..
lg.vsleealelvrsqrpgavpnpgqlrflyefe
|
|||||||||
subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 389-650 | 3e-27 | 90.4 | In-house | 15-270 (288) | alignment | ||
Range on Protein: 389-650
Range on HMM: 15-270/288.0
QSQFETLES---SSPTDDDFDcSIAQLSDNLAKSRVkEHLPPNDY-RVVLStknYDSD-YICASYVDGYRQRSAFIATQGPMKNTAGDFWRMVWEMKSMI
| .|.|. || . | .| . .| .. | |.|| |. || || |.| || | | . . .| .| |.. | . .|.|. |
qiaveglkkeyrdspneasid.iidsfianptrdry.enlprcditrvkls...ddpdfyiaanvvssakykrrlicaqaPlngtieelWkmllesdvey
IIMLTNTEENGEEQSVQYWPVNPNEEDMYGSFNVVAlPEERALPDYIVRKFKLSHSKNPDDSRTITHFQYINWPSTSCPKEATSMIDLVADVvriqrKSG
|.||.. | | |.| .|.|.. |. .| . | ..|| | .|. | ||. ... . . . .|. . |.. | . |. . ||
ivmlcellekGkeksaeyfPsklGekarigrlctvv.kkkradidklvkvsllriskegeekvivkilhlleWdddgvPenylsplrllevl.....ksl
NGPITVHCSDGLGRTGTFCAMFTVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEF
. || ||.| | |||||. .. .|| |. . . . | .. || .| .. || ..|. ||
qkPivvhssaGvGrtgtlililialeslrlddflgirsllaklreerfkaiqtemqylyvhrcvlee
|
|||||||||
0048179 | (Phosphotyrosine protein) phosphatases II | 238-351 | 1.5e-26 | 88.2 | In-house | 48-139 (144) | alignment | ||
Range on Protein: 238-351
Range on HMM: 48-139/144.0
IrtfqlqslhgqgpikeVRQYHFLVWPDHGVPQYATPLLSFQKRVRNHHKgKPGPMVVHCSAGVGRTGTFITIDTMImkidAEGiVDIFNFVRGMRFCRN
. ||..| |||||||.... ||.| . ...... ..||..||||||||||||..... |. .| ..... .. .| .|
e................giqylhlpwpDhgvpdllellleflefieeale.eggpvlVHCsaGvgRtgtlvaaylmk....klg.lsleealalvrsrrp
YMVQTASQYDFLHH
..|.. .|. ||.
gavpnpgqlrfLle
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 126-244 | 2.9e-26 | 87.0 | In-house | 49-183 (350) | alignment | ||
Range on Protein: 126-244
Range on HMM: 49-183/350.0
GKNRYVNIIPYDHSRVTLK-----PDG----NPGSDYINASFIGGL------NSPKDYIATQGPIPAAFPDFWRMIWEYNVPTIIMVTNLKEDDKIKCHQ
||||.||.||.|||| || .|. ..|||||... |. |||||.|.| .. ||...| . .|. |...|.. | . ||..
aknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcyr
YWPSFGAAN-YGSFQVTLKEVETVADYAIRTFQLQ
||. . . .. . ... . | ........
YWqegsydditvklaskwenimgindsslysadvk
|
|||||||||
subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 127-360 | 6.7e-26 | 85.7 | In-house | 46-279 (312) | alignment | ||
Range on Protein: 127-360
Range on HMM: 46-279/312.0
KNRYVNIIPYDHSRVTLKPDGNpgsDYINASFIGGLNSPKDYIATQGPIPAAFPDFWRMIWEYNVPTIIMVTNLKEDDKIKCHQYWPS-FGAANYGSFQV
||| || .| | || | | || | |. |. ...||||. . ||.. .||... . || || .| | . .|
lnrypniqcwdrgrftlagden...fyihanfvkictkperfvctqgplentcthfwqlalslgstsiillcgfvedgsekcakyisdivgfvdledhrv
TL---KEVET--VADYAIRTFQLQ-SLHGQGPIKEVRQYHFLVWPDHGVPQYATPLLSFQKRVRNHHKgkpgPMVVHCSAGVGRTGTFITIDTMIMKIDA
|.| . | |. .. | . .| . |||||.|. | . |.. .| |.. |||||||||||.. |..|| .
yteycteieiggkskdkithrvlkvvvkatgqesklnhyqwaswpdhgmpdscdtalrllsavkkdkk....pviahcsagvgrtgtlaliesmiaalrh
E---GIVDIFNFvrgMRFCRNYMVQTASQYDFLHHAILEAIMCR
. |.| . .| | |.. || . ...|| ....
prkqnvkdsfvl...lrkdrarsvrvfpqyvyalrcvleflysk
|
|||||||||
subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 408-652 | 7.5e-26 | 85.4 | In-house | 45-291 (310) | alignment | ||
Range on Protein: 408-652
Range on HMM: 45-291/310.0
SIAQLSDNLAKSRVKEHLPPNDYRVVLST-KNYDSDYICASYVDGYRQRSAFIATQGPMKNTAGDFWRMVWEMKSMIIIMLTNTEENGEEQSVQYWPVNP
. ... | | . . .. || | | ||| | || ||.|| .|||.. | |||||... .. |..| .. |.| ..| |||
tyeaykkymhknrysdvvcldtsrvklkidksryedyihanyvktnylrstficsqgplqhtiidfwrmifqeraesilllckvgeegrpkcvgywpslg
NEEdMYGSFNVVALPEERALPDYIVRKFKLS-----HSKNPDD--SRTITHFQYINWPSTSCPKEATSMIdlvADvvRIQRKSGNGPITVHCSDGLGRTG
| || | | | . . ..| . .. .. ||| . | | . . |. . || |||| | .|..
vte.tygcirvtnlsesseefeicnlavtfvpdnvpvdeqpanlkelrvslikwpnwpdrgvpdekchtv...pq..rllaqvrhgpcvvhcsagkdrly
TFCAMFTVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFVN
. .|. ...|. . .|. . |. .| .. || .|.. . |.
vvvalklkidkldrglkvdaeevktellksraiciqtelqyliidrvriifar
|
|||||||||
subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 166-350 | 1.2e-25 | 84.8 | In-house | 5-197 (199) | alignment | ||
Range on Protein: 166-350
Range on HMM: 5-197/199.0
KDYIATQGPIPAAFPDFWRMIWEYNVPTIIMVTNLKEDDKIKCHQYWPS--FGAANYGSFQVTLKEVETVADYAIRTFQLQSLHGQGP-IKEVRQYHFLV
. ||||| |. .. |||.|.|| |.|| . . . . |||. |...|||. || | . | .||.| .. | . | .|. .| |
rryiatqhplretmadfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqfts
WPDHGVPQYATP---LLSFQKRVRNHHKGKPGPMVVHCSAGVGRTGTFITIDTMIMKID--AEGIVDIFNFVRGMRFCRNYMVQTASQYDFLH
| .. |. | ... .. ... . | |..|||| | | || |...| . . .||.|. . .| .| .. . .|.|..
wkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiy
|
|||||||||
subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 166-350 | 1.2e-25 | 84.9 | In-house | 4-196 (198) | alignment | ||
Range on Protein: 166-350
Range on HMM: 4-196/198.0
KDYIATQGPIPAAFPDFWRMIWEYNVPTIIMVTNLKEDDKIKCHQYWPS--FGAANYGSFQVTLKEVETVADYAIRTFQLQSLHGQGP-IKEVRQYHFLV
. ||||| |. .. |||.|.|| |.|| . . . . |||. |...|||. || | . | .||.| .. | . | .|. .| |
rryiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqfts
WPDHGVPQYATP---LLSFQKRVRNHHKGKPGPMVVHCSAGVGRTGTFITIDTMIMKID--AEGIVDIFNFVRGMRFCRNYMVQTASQYDFLH
| .. |. | ... .. ... . | |..|||| | | || |...| . . .||.|. . .| .| .. . .|.|..
wkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiy
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 418-574 | 1.2e-25 | 84.8 | In-house | 31-189 (319) | alignment | ||
Range on Protein: 418-574
Range on HMM: 31-189/319.0
KSRVKEHLPPNDYRVVLSTKNYD--SDYICASYVDGYRQR-SAFIATQGPMKNTAGDFWRMVWEMKSMIIIMLTNTEENGEEQSVQYWPVNP--NEEDMY
|||| . .| . |||| . | . |. |||| ||.. . .||.| ...... ||||.||| .| .|. ||. |.| .. .|.| . .....|
ksrvinvvPlPetrvvlqrigdddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlselGikvcaeylPtketldntsly
GSFNVvALPEERALPDYIVRKFKLSHsKNPDDSRTITHFQYiNWPSTSCPKEATSMIDLVAD
| . | .| . . |.. . | . . . || .||. | .|. . | | ...| .. .
Gdilv.tlkgrevkdryaistlllkr.vdkeesrelthywy.kwleaevPaeeaaliamlle
|
|||||||||
subfamily_egg_pd | Subfamily egg | 125-354 | 9e-25 | 82.0 | In-house | 41-267 (307) | alignment | ||
Range on Protein: 125-354
Range on HMM: 41-267/307.0
HGKNRYVNIIPYDHSRVTLK-PDGNPGSDYINASFIGGLNSPKDYIATQGPIPAAFPDFWRMIWEYNVPTIIMVTNLKEDDkiKCHQYWPSFG--AANY-
| | . | |||.|. . | |.| | . | ..| .| |. . |||||... .|. |.|.| || . .|. ||| .. .
lekarskrvhckdssrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvddfwrmvfqeevqyivmltsrkese..rceyywpkaesdslvtv
-GSFQVTLKEVETVADYAIRTFQLQSlhgQGPIKEVRQYHFLVWPDHGVPQYATPLlSFQKRVRNHHKgkpgPMVVHCSAGVGRTGTFITIDTMIMKIDA
||.... .|. || | .|. |. .| | . . . . .|| ...|| | |.||.. || ...|...|.. ....
pGslrienlkvdskadplfrvtklkl...vGgddeerflehwqgdvnnssdvyspl.rvlrklrnlsk....pvvvqdilGvskaatlvaieiallsllr
EGIV--DIFNFVRGMRFCRNYMVQTASQYDFLHHAIL
|. . . | .| |.. |... .| |.. .|
Gpitkslvlravvflrlrrrlsvesvllylfvyrlvl
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 408-575 | 4.6e-24 | 79.8 | In-house | 26-193 (297) | alignment | ||
Range on Protein: 408-575
Range on HMM: 26-193/297.0
SIAQLSDNLAKSRVKEHLPPNDYRVVLSTKNYDSDYICASYVDGY--RQRSAFIATQGPMKNTAGDFWRMVWEMKSMIIIMLTNTEENGEEQSVQYWPVN
| |. . | | | .. | .| || | ..||| | || . .| .|||...| |||..|.| .|.|... .|.| .. . |||
ssakrnsslrknryrdilatddtrvkllrviterdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrdkcapywpsv
PNEEDMYGSFNVVALPEERA-LPDYIVRKFKLSHSknpDDSRTITHFQYINWPSTSCPKEATSMIDLVADV
.| |.. | | . |. ...| . ..|| ..| |...|| | . . . |.|
vqerlkagdvvveflsstsdefdrviltelqliyr...sesrvvrhvqflswpdhGvpsdledlvrfqaqv
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 543-652 | 2e-23 | 77.4 | In-house | 86-195 (440) | alignment | ||
Range on Protein: 543-652
Range on HMM: 86-195/440.0
DDSRTITHFQYINWPSTSCPKEATSMIDLVADVVRIQRKSGNGPITVHCSDGLGRTGTFCAMFTVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQYEF
.|||. ...| || . || | .. .. || | |.||||. |||| | |||| |. ..| | . ||.|| ....| .|| .|. .|| |
iesrtlkqyhyqgwpdkgvpkfagpvlkmiqdvnesqekagngpllvhcsagagrtgviiavdsilreakrsdqidifsfinsmrnnrpqmvqtpeqyaf
IHKAALEFVN
.|.| || .
vheavlegll
|
|||||||||
subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 180-360 | 1.2e-22 | 74.7 | In-house | 105-291 (302) | alignment | ||
Range on Protein: 180-360
Range on HMM: 105-291/302.0
PDFWRMIWEYNVPTIIMVTNLKEDDKIKCHQYWPS--FGAANYGSFQVTLKEVETVAD-YA-IRTFQLQSL-----H-GQGPIKEVRQYHFLVWPDHGVP
.| .| .||| .. .....||.. || .|. | ..| . |. ..|.| . .. ..|.| .. . . | | .| ||||| |
ekhwalieqynvaivvqlcsfvedeekkcaeyysdkvggelkfgrytvktvsvktdleeftdkksfklytveiknekkkkkvkktvdilafsawpdhGap
QYATPLLSFQKRVRNHHKGkpgpMVVHCSAGVGRTGTFITIDTMIMKIDAEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAIMCR
. | . | | . | ..||||||||||||...| | . . |. . | .| || ||...| .| . ..| .
keaytaldilkfcesykkn....vlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqdeqqliylllcvtkglmek
|
|||||||||
subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 387-651 | 1.1e-21 | 71.6 | In-house | 27-285 (302) | alignment | ||
Range on Protein: 387-651
Range on HMM: 27-285/302.0
GFQSQFETLESSSPTDDDfdCSIAQlsDNLAKSRvKEHLPPNDYRVVLSTKNyDSDYICASYVDGYRQRSAFIATQGPMKNTA---GDFWRMVWEMKSMI
...|..... . |.. . .||.|.. .|..| | ..| ... .|..|| |. . | .| | .... .|||||.. |
evkkefkkidtmkvdlek..Ckafk..knlkknq.sedvpildsnlvkleae.pdsyvnaskvevPeltrsiilaQlpkvdsedsveeFWrmvfqekivs
IIMLTNTEENGEeQSVQYWPVNPNEedmYGSFNVVALPEERaLPDYIVRKFKLSHSKNPDDS-R--TITHFQYINWPSTSCPKEATSMIDLVADVvRIQR
. .| .|| . ...| . .. | .. . . . . |.... |.. .. ||.... |.. ...| .|.| .
vvilvgeeelkk.tlselfpkksgd...ykeygkmfvNnrk.VekaeeektryviEvlPegcsnsvlanvyvltnWkqkkvpvkyaeliktaakv.fakk
KSGNGPITVHCSDGLGRTGTFCAMFTVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFV
... .. . | || |.| ......|.|.... . .||..| ||| |. ..|| ... |.| ..
ikadentvivSknGaGRagafltlavaveklqkgkepnikeivksiRsqRpravdslkQyvslyialllyi
|
|||||||||
0048076 | (Phosphotyrosine protein) phosphatases II | 538-649 | 2.3e-21 | 71.4 | In-house | 37-141 (145) | alignment | ||
Range on Protein: 538-649
Range on HMM: 37-141/145.0
HSKNPDDSRTITHFQYINWPSTSCPKEATSMIDLVADVVRIQRKsGnGPITVHCSDGLGRTGTFCAMFTVLErlkaEQvIDVFSTVKTLRIQRPGFVNDI
| .. .|......|..|| ..| . ...... . ..... | ||. |||| |.|||||..|.. .|. .. ........ .| ||||.|
tselellerlgiqylylpwpDhgvpdllellleflefieealke.g.gpvlVHCsaGvgRtgtlvaaylmll....lg.vsleealelvrsqrpgavpnp
DQYEFIHKAALE
.|..|.... ||
gqlrflyefele
|
|||||||||
subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 124-360 | 7.4e-21 | 69.0 | In-house | 47-282 (303) | alignment | ||
Range on Protein: 124-360
Range on HMM: 47-282/303.0
NHGKNRYVNIIPYDHSRVTLKpDgnpgSDYINASFIgGLNSPKDYIATQGPIPAAFPDFWRMIWEYNVPTIIMVTNLKEDDKIKCHQYWPSFG-AANYGS
| |||.|..| |||.| | | | || ||.. |.| | | || |.. . |||.|| | .| .... | ||. . .| ..
nmdknrfvdvicldhskvkls.d....ssyihasyl.eldsskkailtqlplshtaadfwqmiieqkvkcvlllltdseydklggdsvfprnqdflkfee
FQVT---LKEVETVADYAIRTFQLQslhgQGPIKE-VRQYHFLVWPDHGVPQYAT-----PLLSFQKRVRNHHKGKPgpMVVHCSAGVGRTGTFITIDTM
. .|.|| . .... . .| | . .|. || .| .. . | .|.. ...| | .|.||.||| ..|
rsirvgefkrvelgdgwvlkvlsvs....ngdyksflhvhhykawphnsipsdgspkfvkqiwqlqsvlrkysdstp..tvymslsgcgragtfalfeta
IMKIDAEG-IVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAIMCR
. . .| .|. . . .| | . || ||. ... . | ..
hlslhseqasldlvkclenvrngrlhavqnlsqfsvvytllaehvldn
|
|||||||||
subfamily_Sponge-PTP-7_pd | Subfamily Sponge-PTP-7 | 293-357 | 1.9e-20 | 67.0 | In-house | 1-65 (69) | alignment | ||
Range on Protein: 293-357
Range on HMM: 1-65/69.0
MVVHCSAGVGRTGTFITIDTMIMKIDAEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAI
||||||.| |||||||.| . .| .| .||||| |. || || || .| |.| |. ||.
mvvhcssgtgrtgtfiaimvemarikseklvdifnnvqymrkcrpmmvmneieyifihdalveal
|
|||||||||
0048179 | (Phosphotyrosine protein) phosphatases II | 541-645 | 4.9e-20 | 67.2 | In-house | 42-139 (144) | alignment | ||
Range on Protein: 541-645
Range on HMM: 42-139/144.0
NPDDSRTITHFQYINWPSTSCPKEATSMIDLVADVVRIQRksGNGPITVHCSDGLGRTGTFCAMFTVLerlkAEQvIDVFSTVKTLRIQRPGFVNDIDQY
... |.........|| ..| .. ...... . .... .||. |||| |.|||||..|.. .. .. ........ .| .||| | .|.
pefleregiqylhlpwpDhgvpdllellleflefieeale..eggpvlVHCsaGvgRtgtlvaaylmk....klg.lsleealalvrsrrpgavpnpgql
EFIHK
.|...
rfLle
|
|||||||||
subfamily_Sponge-PTP7_pd | Subfamily Sponge-PTP7 | 294-357 | 6.6e-20 | 65.2 | In-house | 1-64 (69) | alignment | ||
Range on Protein: 294-357
Range on HMM: 1-64/69.0
VVHCSAGVGRTGTFITIDTMIMKIDAEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAI
|||||.| |||||||.| . .| .| .||||| |. || || || .| |.| |. ||.
vvhcssGtGrtGtfiaimvemarikseklvdifnnvqymrkcrpmmvmneneymfihdalveal
|
|||||||||
subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 429-648 | 8.6e-20 | 66.0 | In-house | 32-256 (290) | alignment | ||
Range on Protein: 429-648
Range on HMM: 32-256/290.0
DYRVVLS--TKNYDSDYICASYVDgYRQRSAFIATQGPMKN-------TAGDFWRMVWEMKSMIIIMLTNTEENGEEQSV----QYWPVNPNEEDMYGSF
. |||| | . .||| |..| . . ..|.|| | .. | .|| |. . |. ..|| . ||. ...| .| | . .|| .. .
atrvvLkgygkrfnddyiHAnrvt.cpnglrliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCakYvpesvgeelkfkgl
NVVAlPEERALPDYIVRKFKLSHSKNPddSRTITHFQYINWPSTSCPKEATSMIDLVADVvriqrKSGNGPITVHCSDGLGRTGTFCAMFTVLERLK-AE
.| . . | ..|. . . .. |.|| .. .| ... ... ....|. | | . |. ||| ||. | .. |. . .
tvkC.kskekeddvetRelvvkfddee..eftvtHsllkgWnklnvqedtktllsliqkv.....kasktpvivHcvdGiSrsAalaaiilgyQkiaets
QVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAAL
. . . . .|.|| || . . .. |. ...
gsvkledvlkalrkqralaitsalelafvdagiv
|
|||||||||
subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 441-657 | 2.3e-19 | 64.2 | In-house | 67-282 (312) | alignment | ||
Range on Protein: 441-657
Range on HMM: 67-282/312.0
SDYICASYVDGYRQRSAFIATQGPMKNTAGDFWRMVWEMKSMIIIMLTNTEENGEEQSVQYWP-----VNPNEEDMYGSFNVVALPEERAlPDYIVRKFK
|| | .| . |..||||..||. ||... . | ||.|. |.| |....| |. .. .| . .. | | .
nfyihanfvkictkperfvctqgplentcthfwqlalslgstsiillcgfvedgsekcakyisdivgfvdledhrvyteycteieiggks.kdkithrvl
LSHSKNPDDSRTITHFQYINWPSTSCPKEATSMIDLVADVvriqrKSGNGPITVHCSDGLGRTGTFCAMFTVLERLKAEQVIDVFSTVKTLRIQRPGFVN
| . . |.|. || | . |.. | | . |. ||| |.|||||.. . ... |. . .| . || .| |.
kvvvkatgqesklnhyqwaswpdhgmpdscdtalrllsav.....kkdkkpviahcsagvgrtgtlaliesmiaalrhprkqnvkdsfvllrkdrarsvr
DIDQYEFIHKAALEFVNTFDNY
. || . .. |||. . |
vfpqyvyalrcvleflyskgly
|
|||||||||
subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 179-357 | 6.1e-19 | 63.1 | In-house | 41-221 (255) | alignment | ||
Range on Protein: 179-357
Range on HMM: 41-221/255.0
FPDFWRMIWEYNVPTIIMVTNLKEDDKIKCHQYWPSFGAANYGSFQVTLKEVETVADYAIRTFQLQSLHG-QGPIKEVRQYHFLVWPDHGVPQYATPLLS
|...| . ...|.....|... ||..|.| .|.. ...|| .|| .. | | . ..|. |.. |... |. | .|
vdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdeklkladvnvtttkssadvvlrtleitstlgekkkthtvkhysykGWieknaPelareiln
FQKRVRNHhKgkpgPMVVHCSAGVGRTGTFITID----TMIMKIDAEGIVD--IFNFVRGMRFCRNYMVQTASQYDFLHHAILEAI
| ||. | ..|||||.|.||. .|. .. .||. .| |. .... .| |. ..| | | .|. .
ilkvvrds.k....svvvhCstGiGrsaafvlaelvyqkmirsldttetveldylslleelrskrkraihtPlqlafsilmvldlv
|
|||||||||
subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 468-652 | 3.7e-18 | 60.5 | In-house | 40-222 (255) | alignment | ||
Range on Protein: 468-652
Range on HMM: 40-222/255.0
TAGDFWRMVWEMKSMIIIMLTNTEENGEEQSVQYWPVNPNEEDMYGSFNVVALPeerALPDYIVRKFKLSHSKN-PDDSRTITHFQYINWPSTSCPKEAT
| |.... |. ..||.. .|.| |. .|.|.. .| .. ||.. . | ..| .. .|..|..| |. |..|
tvdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdeklkladvnvtttk...ssadvvlrtleitstlgekkkthtvkhysykGWieknaPelar
SMIdlvaDVVRIQRKSgnGPITVHCSDGLGRTGTFCAMFTVLE----RLKAEQ--VIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFVN
. .... |.| .. |||| | ||. .| . | |. . .| | .. || .|.. ... | | |..|
eil....nilkvvrds..ksvvvhCstGiGrsaafvlaelvyqkmirsldttetveldylslleelrskrkraihtPlqlafsilmvldlvf
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 377-504 | 8.8e-18 | 59.1 | In-house | 13-152 (350) | alignment | ||
Range on Protein: 377-504
Range on HMM: 13-152/350.0
KEIAPSSGKTGFQSqfeTLESSSPTDDDfDCSIAQLSDNLAKSRVKEHLPPNDYRVVLS-------TK---NYDSDYICASYVDGY----RQRSAF--IA
| | . ... .. .|||.| .. . | ... . || | |. || . || | .| .||| |.|. .. . | ||
kliitknstvksrl...sLesdsespsn.DvilseGvelfaknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYia
TQGPMKNTAGDFWRMVWEMKSMIIIMLTNTEENGEEQSVQYWPV
||.|...| ||.... . | .|..||. |.. |. .||.
tqaPlpstvddfykvillnkvkvilsltsdvelnlekcyrYWqe
|
|||||||||
subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 124-357 | 1.1e-17 | 58.5 | In-house | 51-285 (302) | alignment | ||
Range on Protein: 124-357
Range on HMM: 51-285/302.0
NHGKNRYVNIIPYDHSRVTLKpdgNPGSDYINASFIGGLNSPKDYIATQGPIPAAF---PDFWRMIWEYNVPTIIMVTNLKEDDKiKCHQYWP--SFGAA
| ||. .. .|. .| |. . .|.||| . . . | .| |. .||||... .. .. .. .| .| ....| |
nlkknqsedvpildsnlvkle...aepdsyvnaskvevPeltrsiilaQlpkvdsedsveeFWrmvfqekivsvvilvgeeelkk.tlselfpkksgdyk
NYGSFQVTLKEVETVADYAiRTFQLQSL-HG--QGPIKEVrqYHFLVWPDHGVPQYATPLLSFQKRVRNHHKGKPGPMVVHCSAGVGRTGTFITIDTMIM
.||.. | . || . . . . . | .| . .. .| |.. |... ||. . | . | ... ..|. |.|| |.|.| . .
eygkmfvNnrkVekaeeek.tryviEvlPegcsnsvlanv..yvltnWkqkkvpvkyaeliktaakvfakkikadentvivSknGaGRagafltlavave
KIDAEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAI
|.... . | . |. .| | .|....|| .|. |.| |
klqkgkepnikeivksiRsqRpravdslkQyvslyialllyi
|
|||||||||
subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 410-646 | 9.1e-17 | 55.6 | In-house | 42-274 (303) | alignment | ||
Range on Protein: 410-646
Range on HMM: 42-274/303.0
AQLSDNLAKSRVKEHLPPNDYRVVLStknyDSDYICASYVDGYRQRSAfIATQGPMKNTAGDFWRMVWEMKSMIII-MLTNTEENgEEQSVQYWPVNPNE
|. .|. | | . . . .| || || || |||.. .. | | || |. || |||.|. | | .. .||..| . . .| | .
nqfvknmdknrfvdvicldhskvkls....dssyihasyleldsskka.iltqlplshtaadfwqmiieqkvkcvlllltdseyd.klggdsvfprnqdf
EDMYGSFNVVALPEERALPDYIVRKfkLSHSKNPDDSRTITHFQYINWPSTSCPKE-ATSMIDLVADVVRIQRKSGNGPITVHCS-DGLGRTGTFCAMFT
.. . | . | | | | . | | . .| .|| .| | . . .. . .. . || .. ||. | | ||.|||. . |
lkfeersirvgefkrvelgdgwvlk..vlsvsngdyksflhvhhykawphnsipsdgspkfvkqiwqlqsvlrkysdstptvymslsgcgragtfalfet
VLERLKAEQV-IDVFSTVKTLRIQRPGFVNDIDQYEFIHKA
|..|| .|. ....| | |... |. ...
ahlslhseqasldlvkclenvrngrlhavqnlsqfsvvytl
|
|||||||||
subfamily_hpo-7_pd | Subfamily hpo-7 | 467-651 | 1.3e-16 | 55.4 | In-house | 45-227 (263) | alignment | ||
Range on Protein: 467-651
Range on HMM: 45-227/263.0
NTAGDFWRMVWEMKSMIIIMLTNTEENGEEQSVQYWPVNPNEEDMYGSFNVVALPEERalpDYIVRKFKLSH-SKNPDDSRTITHFQYINWPSTSCPKEA
.| |.... |. ..||.. .|.| |. .|.|.. .| .. ||.. | ... .| .. .|..|..| |. . |..|
qtidkfyqtivqtktevvvmLcDfneegvekcssyfPlekdekqklanvnvcttkvqs...dvllktlellstlgeKkkthtvkhysykgWiekndpela
TSMIdlvaDVVRIQRKSgnGPITVHCSDGLGRTGTFCAMFTVLE----RLKAEQ--VIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFV
... .... |.| .. |||| | ||. | . .| |. . .| | .. || .|.. ... | | |.||
reil....nilkvarns..kslvvhcstGiGrsaafsvaElvyqkmirsldttstveldylsLleelrssrkraihtPmqLafsilmvLdfv
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 578-651 | 1.7e-16 | 54.8 | In-house | 241-315 (319) | alignment | ||
Range on Protein: 578-651
Range on HMM: 241-315/319.0
IQRKSGNGPITVHCSDGLGRTGTFCAMFTVLERLKAE-QVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFV
... .||..|||||| ||||. | ...|. . .|. .| .| .| | ...|||||.| . |.
sgtresqGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefiykvlseya
|
|||||||||
subfamily_eak_pd | Subfamily eak | 128-281 | 2.4e-16 | 54.0 | In-house | 56-206 (332) | alignment | ||
Range on Protein: 128-281
Range on HMM: 56-206/332.0
NrYVNIIPYDHSRVTLKPDGNPGSDYINASFIGGLNSPKDYIATQGPIPAAFPDFWRMIWEYNVPTIIMVTNLKEDDKIKCHQYWPSFG--AANYGSFQV
| |.|.|||. | | . ||||| . . . || | . . ||.|. | . |.|... . | . | .|.| . ..| ..|
n.vvkivpydrylvrltssqlnrlGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledvelkleksdkyfpdktreelkfGildv
TLKEVETVADYAIRTFQLQslHGQgPIKEVRQYHFLVWPDHGVPQYATpLLSFQKR
. || . . | ..|. | ..| |.. | . .|.| .|...|
erkefvkrniletrllels..kGn.ethrvlhykvfGwtettlpkyed.flalrkv
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 126-228 | 5.1e-16 | 52.9 | In-house | 50-166 (349) | alignment | ||
Range on Protein: 126-228
Range on HMM: 50-166/349.0
GKNRYVNIIPYDHSRVTLKPDG---------------NPGSDYINASFI--GGLNSPKDYIATQGPIPAAFPDFWRMIWEYNVPTIIMVTNLKEDDKIKC
|||| .|.||.|||| || ||||| .. .. | ||||| |.|.. ||...| .|. .. ... || . ||
aknrykdilPyehsrvklkkslksskvikastsesdsgklddyinanylkltrisvekkyiatqaPlPstvddfykvillngvklvlsLnddkelslekc
HQYWPSfgaANYGSFQVTLK
..|| .| ...| |.
diywqe...lsysnitvklq
|
|||||||||
subfamily_hpo-7_pd | Subfamily hpo-7 | 178-358 | 1.7e-15 | 51.7 | In-house | 46-228 (263) | alignment | ||
Range on Protein: 178-358
Range on HMM: 46-228/263.0
AFPDFWRMIWEYNVPTIIMVTNLKEDDKIKCHQYWPSFGAANYGSFQVTLKEVETVADYAIRTFQLQSLHG-QGPIKEVRQYHFLVWPDHGVPQYATPLL
. . |...| . ...|... .|... || .|.| .|.. ... | ..| .| | | . ...|..| . |... |. | |
tidkfyqtivqtktevvvmLcDfneegvekcssyfPlekdekqklanvnvcttkvqsdvllktlellstlgeKkkthtvkhysykgWiekndpelareil
SFQKRVRNHhKgkpgPMVVHCSAGVGRTGTFITID----TMIMKIDAEGIVD--IFNFVRGMRFCRNYMVQTASQYDFLHHAILEAIM
| .|| | ..|||||.|.||. | .. .||. .| |. .... .| |. ..| | | .|. ..
nilkvarns.k....slvvhcstGiGrsaafsvaElvyqkmirsldttstveldylsLleelrssrkraihtPmqLafsilmvLdfvl
|
|||||||||
subfamily_Sponge-PTP7_pd | Subfamily Sponge-PTP7 | 589-649 | 1.7e-15 | 51.1 | In-house | 2-62 (69) | alignment | ||
Range on Protein: 589-649
Range on HMM: 2-62/69.0
VHCSDGLGRTGTFCAMFTVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALE
|||| | |||||| |. . |.|.|...|.| |. .| || | . ..| ||| | |
vhcssGtGrtGtfiaimvemarikseklvdifnnvqymrkcrpmmvmneneymfihdalve
|
|||||||||
subfamily_Sponge-PTP-7_pd | Subfamily Sponge-PTP-7 | 588-649 | 1.9e-15 | 51.0 | In-house | 2-63 (69) | alignment | ||
Range on Protein: 588-649
Range on HMM: 2-63/69.0
TVHCSDGLGRTGTFCAMFTVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALE
|||| | |||||| |.. . |.|.|...|.| |. .| || | . .| ||| | |
vvhcssgtgrtgtfiaimvemarikseklvdifnnvqymrkcrpmmvmneieyifihdalve
|
|||||||||
subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 462-642 | 6.3e-15 | 49.4 | In-house | 97-279 (302) | alignment | ||
Range on Protein: 462-642
Range on HMM: 97-279/302.0
QGPMKNTAGDFWRMVWEMKSMIIIMLTNTEENGEEQSVQYWPVNPNEEDMYGSFNVVALPEERALPDYIVRK-FKL-----SHS-KNPDDSRTITHFQYI
| |.| .| .. . . |.. |.. |..|.. .|. . ..| .| . | .. . | .. .| ||| . |. . .|. ...
ivpkkstlekhwalieqynvaivvqlcsfvedeekkcaeyysdkvggelkfgrytvktvsvktdleeftdkksfklytveiknekkkkkvkktvdilafs
NWPSTSCPKEATSMIDLVADVvriqrKSGNGPITVHCSDGLGRTGTFCAMFTVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQYEF
|| |||| . .|.. .| . |||| |.|||||. |. .. . ..| |. | |. .| | | |.| .| .
awpdhGapkeaytaldilkfc.....esykknvlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqdeqqliy
|
|||||||||
subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 122-214 | 6.7e-15 | 49.4 | In-house | 94-180 (244) | alignment | ||
Range on Protein: 122-214
Range on HMM: 94-180/244.0
PINHGKNRYVNIIPYDHSRVTLKpDGNPGSDYINASFIGGLNSPKDYIATQGPIPAAFPDFWRMIWEYNVPTIIMVTNLKEDDkikchQYWPS
| | ||| .|.| .|| | |. | ||||||.| | .|| || |. . |||.|. | | .... ..|.| .|||
pnnswknregaglpfdfnrvpls.kgsmgntyinasfvgclgrtaeyiltqhpladtsmdfwkmmlerhvnvlvvlgsveeed.....eywpd
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 283-353 | 1.6e-14 | 48.3 | In-house | 240-311 (319) | alignment | ||
Range on Protein: 283-353
Range on HMM: 240-311/319.0
RNHHKGKPGPMVVHCSAGVGRTGTFITIDTMIMKIDAE-GIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAI
|. .. . ||.||||| ||||||. |. | | ... ||| . | .| | |.| ||.|... .
rsgtresqGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefiykvl
|
|||||||||
subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 414-560 | 1.6e-13 | 44.9 | In-house | 95-234 (244) | alignment | ||
Range on Protein: 414-560
Range on HMM: 95-234/244.0
DNLAKSRVKEHLPPNDYRVVLSTKNYDSDYICASYVDGYRQRSAFIATQGPMKNTAGDFWRMVWEMKSMIIIMLTNTEENGEeqsvqYWPVNpNEEDMYG
.| |.| || . || || . || ||.| . . .| || |. .|. |||.|. | . ....| ||. | ||| . . |
nnswknregaglpfdfnrvplskgsmgntyinasfvgclgrtaeyiltqhpladtsmdfwkmmlerhvnvlvvlgsveeede.....ywpds.eplewye
SFNVVALPEERALPDYIVRKFKLSHSKNpDDSRTITHFQYINWPSTS
|.| . . . .... | . ...| || ||||
editvtltdrdefknikasnleiesdmn.eshqaltmfqisnwpsdg
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 288-357 | 3.9e-13 | 43.9 | In-house | 226-295 (297) | alignment | ||
Range on Protein: 288-357
Range on HMM: 226-295/297.0
GKPGPMVVHCSAGVGRTGTFITIDTMIMKIDAEGIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAI
.. ...|||||||||.| . |... |. . | |. ... .| | .||| |...|..|.|. .
prnayllvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqtleqfellydavlkkl
|
|||||||||
subfamily_eak_pd | Subfamily eak | 411-564 | 1.6e-12 | 41.5 | In-house | 48-197 (332) | alignment | ||
Range on Protein: 411-564
Range on HMM: 48-197/332.0
QLSDNLAKSrVKEHLPPNDYRVVLS-TKNYDSDYICASYVDGYRQRSAFIATQGPMKNTAGDFWRMVWEMKSMIIIMLTNTEENGEEQSVQYWPVNPNEE
. ... . | . .| . | | |. .. || || .. .| | . .. ||.|| | || |..| . |.. |.| .|.| . ||
arleavnrn.vvkivpydrylvrltssqlnrlGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledvelkleksdkyfpdktree
DMYGSFNVVALPEeRALPDYIVRKFKLSHSknpDDSRTITHFQYINWPSTSCPKE
.| ..| . .|...|| ... . |... | |. ||
lkfGildverkef.vkrniletrllelskG...nethrvlhykvfGwtettlpky
|
|||||||||
subfamily_Sponge-PTP3_pd | Subfamily Sponge-PTP3 | 80-173 | 2.5e-12 | 40.8 | In-house | 4-95 (95) | alignment | ||
Range on Protein: 80-173
Range on HMM: 4-95/95.0
PLNVSDFIEMMALLQSNNSDRLEEEYPDIELEWNFTSYAAKLPINHGKNRYVNIIPYDHSRVTLKPDgnPGSDYINASFIGGLNSPKDYIATQG
|. || | . ..|| . ...|. | . . . | |||..||.||| .||.| |||||| |. | . |||.||
pihvsvfhshvlemhsnsdqefdnefksismtsgapytvgsseanipknrflnifpydatrvvlttk..rdsdyinacfvdgyarkncyiaaqg
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 80-164 | 1.1e-11 | 38.7 | In-house | 5-88 (440) | alignment | ||
Range on Protein: 80-164
Range on HMM: 5-88/440.0
PLNVSDFIEMMalLQSNNSDRLEEEYPDIELEWNFTSYAAKLPINHGKNRYVNIIPYDHSRVTLK-PDGNPGSDYINASFIGGLNS
|. |.|| ... .. | |.|. . | | || |. |||| ||. |||||| |. | | |||||||.| |..|
piivadfadyv..qnnrrsrafedewsllpsglsqpsdiaslpnnkvknryrnilaydhsrvmleevkgvpdsdyinasyingies
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 582-651 | 1.6e-11 | 38.6 | In-house | 226-295 (297) | alignment | ||
Range on Protein: 582-651
Range on HMM: 226-295/297.0
SGNGPITVHCSDGLGRTGTFCAMFTVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFV
| .. |||| |.||.| ..|..|. ... || . .. || ||. |. ..|.|....|.|. .
prnayllvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqtleqfellydavlkkl
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 167-244 | 2e-11 | 37.9 | In-house | 237-312 (440) | alignment | ||
Range on Protein: 167-244
Range on HMM: 237-312/440.0
DYIATQGPIPAAFPDFWRMIWEYNVPTIIMVTNLKedDKiKCHQYWPSFG-AANYGSFQVTLKEVETVADYAIRTFQLQ
.|||| |. .. ||||.. .|.. ||||. .|. || | ||| . .| | | | | . .||..|.
afiatqmpldstvldfwrlvhdyristiimlnqln..dk.tcsiywpvntrsvtfgpftvghkgsenmnrvkvrtlelk
|
|||||||||
I-set | Immunoglobulin I-set domain | 2-66 | 2.2e-11 | 35.4 | Pfam-A | 22-90 (90) | alignment | ||
Range on Protein: 2-66
Range on HMM: 22-90/90.0
CESTGTPAPTISWHKEGMILEEPDYVQFN-DG---SLYITNTKLKDQGHFIVRATNNIGVVEETVRVTV
|. .|.| |..||.|.| |.. . |... .. .| |.| . .|.| . ..|||..| .|......|
ctveGepepsvsWakdgselkssqrvkvtveeaeytLtIsnvevsDeGkYtckatnsagkaeakaeLkV
|
|||||||||
subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 136-364 | 2.2e-11 | 38.5 | In-house | 30-257 (290) | alignment | ||
Range on Protein: 136-364
Range on HMM: 30-257/290.0
YDHSRVTLKPDGNP-GSDYINASFIGgLNSPKDYIATQGPIPAA-------FPDFWRMIWEYNVPTIIMVTNLKEDDKI----KCHQYWPSFG--AANYG
..|| || |. .||| |... . |.|| | . .|| |. . .| ..|. . .| .. | .| | ...
veatrvvLkgygkrfnddyiHAnrvt.cpnglrliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCakYvpesvgeelkfk
SFQVTLKEVETVADYAIRTFQLQslHGQGPIKEVRQYHFLVWPDHGVPQYATPLLSFQKRVRNHHkgkpGPMVVHCSAGVGRTGTFITIDTMIMKID-AE
..| |. |.. | .|. .. .... | . . | . |.. ||| . |.... |..||| |. | .. .|. || .
gltvkCkskekeddvetRelvvk..fddeeeftvtHsllkgWnklnvqedtktllsliqkvkask....tpvivHcvdGiSrsAalaaiilgyQkiaets
GIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILeaimcrdttI
| | . . . .| |. ....| .. | .|. .
gsvkledvlkalrkqralaitsalelafvdagiv.........l
|
|||||||||
0038934 | (Phosphotyrosine protein) phosphatases II | 550-640 | 2.4e-11 | 39.1 | In-house | 79-172 (194) | alignment | ||
Range on Protein: 550-640
Range on HMM: 79-172/194.0
HFQYINWPS---TSCPkEATSMIDLVADVVRIQRKSGNGPITVHCSDGLGRTGTFCAMFTVL-ERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQY
..|...| ..| . . . | .. ... .| . ||| |||||||..| . . ...||. |. |. .. |......... ..
gieylklpfpddgtvP.sleillrfldlvdeflnedpggvvaVHCkaGlgRtGtlvaaYLiyrlgmsaeeAialfrekRpgaipnqdyleallkr
|
|||||||||
subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 125-209 | 3.3e-11 | 37.3 | In-house | 38-128 (347) | alignment | ||
Range on Protein: 125-209
Range on HMM: 38-128/347.0
HGKNRYVNIIPYDHSRVTLKPDG------NPGSDYINASFIGGLNSPKDYIATQGPIPAAFPDFWRMIWEYNVPTIIMVTNLKEDDKIKCH
||| . | .|| | |. .. ||||| | |. |.|| || |.| . |||.|. .| .. . . ..|. |.
lsknrskdvklidatrvvlspeksknsraddvetyinashikfdnaskeyiltqyplpdtvrdfwkmvsvtkvtqvvtifepikdeaieef
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 450-517 | 3.5e-11 | 37.1 | In-house | 230-293 (440) | alignment | ||
Range on Protein: 450-517
Range on HMM: 230-293/440.0
DGYRQRSAFIATQGPMKNTAGDFWRMVWEMKSMIIIMLTNTEEngEeQSVQYWPVNPNEeDMYGSFNV
.|| .. |||||| |. | ||||.| . . |||| . .. ||||| .| | |
egyskknafiatqmpldstvldfwrlvhdyristiimlnqlnd..k.tcsiywpvntrs.vtfgpftv
|
|||||||||
subfamily_Cele-PTP-12_pd | Subfamily Cele-PTP-12 | 414-534 | 3.6e-11 | 37.1 | In-house | 33-153 (332) | alignment | ||
Range on Protein: 414-534
Range on HMM: 33-153/332.0
DNLAKSRVKEHLPPNDYRVVLSTKNYDSDYICASYVDGYRQRSAFIATQGPMKN-TAGDFWRMVWEMKSMIIIMLTNTEENGEEQSVQYWPVNPNEEDMY
.|. |. . || |. .. |. ||.|||| ..||.| .| |... | ||||| | | .|... . .|. . .. |. .
nnmdmnriphlycfdhsrvelapqdgkddfynaswvdgyskksayifaqapfndhteyvfwrmvserkpsmilvfgdidekqkrkapydisdrgfeksfl
GSFNVVALpEERALPDYIVRKF
| .| || | |.|||
hefgaksl.eecelkakicrkf
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 284-354 | 5.3e-11 | 36.8 | In-house | 255-341 (350) | alignment | ||
Range on Protein: 284-354
Range on HMM: 255-341/350.0
NHHK-GKPGPMVVHCSAGVGRTGTFITIDTMIM-------------KIDAEG-IV-DIFNFVRGMRFCRNYMVQTASQYDFLHHAIL
.| . . |..||||||||||||..|.| .. |.| . |. | .| | |||. |. |...|.|
shldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlisiivnelrkqrismvqnldqfifiYeall
|
|||||||||
subfamily_Sponge-PTP-4_pd | Subfamily Sponge-PTP-4 | 134-226 | 8.1e-11 | 36.4 | In-house | 3-83 (130) | alignment | ||
Range on Protein: 134-226
Range on HMM: 3-83/130.0
IPYDHSRVTlkpdgnpGSDYINASFIGGLNSPKDYIATQGPIPAAFPDFWRMIWEYNVPTIIMVTNLKEDDkikchQYWPSFGAANYGSFQVT
.... ||. | .||||||.| |. ..|. || |. .. |||.|. | | .... ..|.| .||| .. ...
lefevsrlq.......gntyinasfvGllgrtaeylltqhpladtsmdfwkmmleryvnvlvvlgsveeed.....eywpdsePlewyeedii
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 547-650 | 1.1e-10 | 35.8 | In-house | 216-343 (350) | alignment | ||
Range on Protein: 547-650
Range on HMM: 216-343/350.0
TITHFQYINWPST---SCPKEATSMID----LVADVV-R-IQRKSGNGPITVHCSDGLGRTGTFCAMFTVLE------RLK--------AEQVID-VFST
. ..|. ||. |.. .... |. | . . .. || |||| | |||||.... .|. |. | .. | .. .
vvyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlisii
VKTLRIQRPGFVNDIDQYEFIHKAALEF
|. || || | ..||. ||..|.| .
vnelrkqrismvqnldqfifiYeallfy
|
|||||||||
subfamily_Sponge-PTP-4_pd | Subfamily Sponge-PTP-4 | 440-560 | 2.4e-10 | 34.8 | In-house | 12-125 (130) | alignment | ||
Range on Protein: 440-560
Range on HMM: 12-125/130.0
DSDYICASYVDGYRQRSAFIATQGPMKNTAGDFWRMVWEMKSMIIIMLTNTEENGEeqsvqYWPVNpNEEDMYGSFNVVALPeERALPDYIVRKFkLSHS
. .|| ||.| . . .. || |. .|. |||.|. | ....| ||. | ||| . . | .|.| .| ..| .. | .
gntyinasfvGllgrtaeylltqhpladtsmdfwkmmleryvnvlvvlgsveeede.....ywpds.ePlewyeediivtlt.drdefknikasn.leie
KNPDD-SRTITHFQYINWPSTS
.. . ...| || ||||
sdlneshqaltmfqisnwpsdg
|
|||||||||
subfamily_Sponge-PTP3_pd | Subfamily Sponge-PTP3 | 409-463 | 1e-09 | 32.5 | In-house | 42-95 (95) | alignment | ||
Range on Protein: 409-463
Range on HMM: 42-95/95.0
IAQLSDNLAKSRVKEHLPPNDYRVVLSTKNyDSDYICASYVDGYRQRSAFIATQG
. |. | |. . .| . ||||.|| ||||| | .|||| .. ..||.||
vgsseanipknrflnifpydatrvvlttkr.dsdyinacfvdgyarkncyiaaqg
|
|||||||||
0038934 | (Phosphotyrosine protein) phosphatases II | 254-349 | 1.3e-09 | 33.5 | In-house | 78-169 (194) | alignment | ||
Range on Protein: 254-349
Range on HMM: 78-169/194.0
EVRQYHFLVWPDHGVPQYATPLLSFQKRVRN-HHKGKPGPMVVHCSAGVGRTGTFITIDTMI-MKIDAEGIVDIFNFVRgmrfcrNYMVQTASQYDFL
.|. | .||.|.. ||.| . | ... ..| .||| ||.|||||.. . ....|| ...|...| . .... .... |
agieylklpfpddgtvPsleillrfldlvdeflnedpggvvaVHCkaGlgRtGtlvaaYLiyrlgmsaeeAialfrekR......pgaipnqdyleal
|
|||||||||
subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 406-492 | 6e-09 | 29.9 | In-house | 28-123 (347) | alignment | ||
Range on Protein: 406-492
Range on HMM: 28-123/347.0
DCSIAQLSDNLAKSRVKEHLPPNDYRVVLSTKNYD-------SDYICASYVDGYRQRSAFIATQGPMKNTAGDFWRMVWEMKSMIIIMLTN--TEE
... .. .|.| | |.. .. ||||| .. . || ||.. . .| || |. .| |||.|| .| .. . . ..|
kftsvewekslsknrskdvklidatrvvlspeksknsraddvetyinashikfdnaskeyiltqyplpdtvrdfwkmvsvtkvtqvvtifepikde
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 289-355 | 1.4e-08 | 28.4 | In-house | 264-342 (349) | alignment | ||
Range on Protein: 289-355
Range on HMM: 264-342/349.0
KPGPMVVHCSAGVGRTGTFITIDTMIM----------KIDAEGIV--DIFNFVRGMRFCRNYMVQTASQYDFLHHAILE
. ...|||||| ||||...|.| .. ||. . . |. | .| | ||| .|......|.|.
qlstllvhcsaGcGrtGvlvtldlllsileplqnesnkiklqallkDlisiivnelrkqrismvqnlaqfiaiyealLk
|
|||||||||
subfamily_CDC14_pd | Subfamily CDC14 | 571-643 | 1.7e-08 | 28.7 | In-house | 251-317 (328) | alignment | ||
Range on Protein: 571-643
Range on HMM: 251-317/328.0
LVADVVRIQRKSgNGPITVHCSDGLGRTGTFCAMFTVLE-RLKAEqvidvfSTVKTLRIQRPGFVNDIDQYEFI
.| ..| |. .| |.||| |||||||. | . . . |. |. .. ||| ||| | | ..
ivkkfleiaeka.eGaiavhCkaGLGrtGtLiacylmkhyrftaa......eaiawlricrPGsvigpqqkfle
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 439-503 | 2.3e-08 | 27.8 | In-house | 88-154 (349) | alignment | ||
Range on Protein: 439-503
Range on HMM: 88-154/349.0
YDSDYICASYVDGYR--QRSAFIATQGPMKNTAGDFWRMVWEMKSMIIIMLTNTEENGEEQSVQYWP
||| | |. | .|||| |. | ||.... . ... |.. .|.. |. .||
klddyinanylkltrisvekkyiatqaPlPstvddfykvillngvklvlsLnddkelslekcdiywq
|
|||||||||
subfamily_Cele-PTP-12_pd | Subfamily Cele-PTP-12 | 123-208 | 3.9e-08 | 27.1 | In-house | 33-118 (332) | alignment | ||
Range on Protein: 123-208
Range on HMM: 33-118/332.0
INHGKNRYVNIIPYDHSRVTLKPDGNpGSDYINASFIGGLNSPKDYIATQGPIPAAF-PDFWRMIWEYNVPTIIMVTNLKEDDKIKC
| || . .||||| | |. |. |||.. | . || .| |. ||||. | . |... .. | .| |.
nnmdmnriphlycfdhsrvelapqdg.kddfynaswvdgyskksayifaqapfndhteyvfwrmvserkpsmilvfgdidekqkrka
|
|||||||||
subfamily_Sponge-PTP-2_pd | Subfamily Sponge-PTP-2 | 113-214 | 5e-08 | 26.1 | In-house | 16-86 (169) | alignment | ||
Range on Protein: 113-214
Range on HMM: 16-86/169.0
NFTSYAAKLPINHGKNRYVNIIPYDHSRVTLKP-DGNPGSDYINAsfigglnspkdyiatqgpipaafpdfwRMIWEYNVPTIIMVTNlkEDDKikcHQY
.. . |.| .|. ||| . | || |. . ||||||| ||||| | |... . ||| ..
eynnfmaeltcnetknrpagplapshtrvklqrvmedlgsdyina...........................rmiwetnasvivvlgd..tddk...nnf
WPS
||
wpe
|
|||||||||
subfamily_PTPDC1_pd | Subfamily PTPDC1 | 569-641 | 6.4e-08 | 27.2 | In-house | 98-172 (182) | alignment | ||
Range on Protein: 569-641
Range on HMM: 98-172/182.0
IDLVADVVRIQRK-SGNGPITVHCSDGLGRTGTFCAMFTVL-ERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQYE
.. . |.|.. .| ..||| |||||| | . | .||.||. |.. .. || . |. . ...
leriLdivkvvafalqegkvavhChaGlGrtGvliacylvyakrltaekaiklvrskrpksiqtreqvelvkefa
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 581-651 | 7.1e-08 | 26.1 | In-house | 262-344 (349) | alignment | ||
Range on Protein: 581-651
Range on HMM: 262-344/349.0
KSGNGPITVHCSDGLGRTGTFCAMFTVLE---RL---------KAEQVIDVFSTVKTLRIQRPGFVNDIDQYEFIHKAALEFV
.. .. |||| | ||||... . .|. | .| . .. .| .|| || |... |. .|..| |...
tdqlstllvhcsaGcGrtGvlvtldlllsileplqnesnkiklqallkDlisiivnelrkqrismvqnlaqfiaiyealLkyf
|
|||||||||
subfamily_eak_pd | Subfamily eak | 284-364 | 7.4e-08 | 26.1 | In-house | 230-312 (332) | alignment | ||
Range on Protein: 284-364
Range on HMM: 230-312/332.0
NHHKGKPGPMVVHCSAGVGRTGTFITIDTMIMKIDAE--GIVDIFNFVRGMRFCRNYMVQTASQYDFLHHAILEAIMCRDTTI
.| .. .. | |.|.|. || .| ||. . ... .. |.. | .| |. |.....|. .. |. .
yihtppsfapiiqsarGsaraGvfvvidllirlidnkkknlysvedlilkvkskrihsvlvalqhsfiyeivldyllrrnnrl
|
|||||||||
subfamily_Sponge-PTP2_pd | Subfamily Sponge-PTP2 | 113-214 | 7.7e-08 | 25.3 | In-house | 15-85 (169) | alignment | ||
Range on Protein: 113-214
Range on HMM: 15-85/169.0
NFTSYAAKLPINHGKNRYVNIIPYDHSRVTLKP-DGNPGSDYINAsfigglnspkdyiatqgpipaafpdfwRMIWEYNVPTIIMVTNlkEDDKikcHQY
.. . |.| .| ||| . | || |. . ||||||| ||||| | |... . ||| ..
eynnfmaeltcnetknrpagplapshtrvklqrvmedlgsdyina...........................rmiwetnasvivvlGd..tddk...nnf
WPS
||
wpe
|
|||||||||
ig | Immunoglobulin domain | 2-45 | 1.5e-07 | 22.7 | Pfam-A | 8-58 (64) | alignment | ||
Range on Protein: 2-45
Range on HMM: 8-58/64.0
CES-TGTPAPTISWHKEGMILEEPDYVQFNDGS------LYITNTKLKDQG
|.. .|.| ...|| ||| |||...... . . | |.|.. | |
CsvssgppstdvsWykegkgleesqktgvvenrvsaqevLtinnvtkedsG
|
|||||||||
subfamily_DSP23_pd | Subfamily DSP23 | 572-645 | 3.2e-07 | 25.1 | In-house | 70-140 (148) | alignment | ||
Range on Protein: 572-645
Range on HMM: 70-140/148.0
VADVVRIQR--KSGNGPITVHCSDGLGRTGTFCAMFTVLERlkaeqVIDVFSTVKTLRIQRPGFVNDIDQYEFIHK
| . ||. .. | ..||| | |||||. | . | || . .. .| .||| |. ..| . ...
vvefvrvveeaeekneavsvhcllgrgrtgtmlacylvker.....klaaaeaiaevrrlrpgsvetveqeklvrd
|
|||||||||
subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 113-156 | 5.3e-07 | 23.5 | In-house | 28-71 (244) | alignment | ||
Range on Protein: 113-156
Range on HMM: 28-71/244.0
NFTSYAAKLPINHGKNRYVNIIPYDHSRVTLKPDGNPGSDYINA
.| | | | ||||.||.|.|..|| | . |||||||
eflqtnavlsanatknryinilpfdetrvilssskkegsdyina
|
|||||||||
PTEN_1 | 550-622 | 7.5e-07 | 24.1 | In-house | 94-169 (196) | alignment | |||
Range on Protein: 550-622
Range on HMM: 94-169/196.0
HFQYINWPSTSCPKEATSMIDLVADVVRIQRK--SGNGPITVHCSDGLGRTGTFCAMFTVLER-LKAEQVIDVFST
...|.. | . ... |.. ..... ... . .. . ||| ||||.|| .|.. . . | |.. .. .
gveylhfpieDhgapslselfdicksfiewllsdpngnvVlVHCkaGlgRsGtvvaayLmykgkltadeAlelvre
|
|||||||||
0048567 | (Phosphotyrosine protein) phosphatases II | 551-642 | 1.3e-06 | 22.9 | In-house | 33-130 (157) | alignment | ||
Range on Protein: 551-642
Range on HMM: 33-130/157.0
F------QYINWPSTSCPKEATSMIDLVADVVRIQR--KSGNGPITVHCSDGL---GRTGTFCAMFTVLE-RLKAEQVIDVFstvktlRIQRPGFVNDID
| .|... | . . .... . .. . . ...| |||. || |||.|... . .| .. .|..|. . || |||.| |
FsiddglvyedfffdfGPlnlailyrFilklnkflkilelagkaiavhckaglkkrgrtatLigcYlilhlgftpeeaiapl......rivrpgsvpfrd
QYEF
.. .
asyl
|
|||||||||
Ig_2 | Immunoglobulin domain | 1-66 | 1.7e-06 | 20.0 | Pfam-A | 20-80 (80) | alignment | ||
Range on Protein: 1-66
Range on HMM: 20-80/80.0
MCESTGTPAPTISWHKEGMILEepdyV---QfndgsLYITNTKLKDQGHFIVRATN-NIGVVEETVRVTV
.|...| |.|...| |.| .|. . |.| |. ..|.|.. ||.| . . . ..|.|||
tCqapgnptpkvqwykdgeels....qsqna.....lfipnvsaedsGtYtCrasnsegskqsnsvevtv
|
|||||||||
subfamily_DSP11_pd | Subfamily DSP11 | 566-639 | 2.1e-06 | 21.8 | In-house | 99-172 (178) | alignment | ||
Range on Protein: 566-639
Range on HMM: 99-172/178.0
TSMIDLVADVVRIqRKSGNGPITVHCSDGLGRTGTF-CAMFTVLERLKAEQVIDVFSTVKTLRIQRPGFVNDIDQ
..... | . . .| . |.||| .|. ||| . | . | ...|. |..|.... ..| ...|. .
kkfkeavkeflek.nkdndkligvhCthGvnrtGyliCrylidvegyepedaieafeearGhslerenylkdLkk
|
|||||||||
subfamily_CDC14_pd | Subfamily CDC14 | 288-349 | 2.2e-06 | 21.8 | In-house | 261-316 (328) | alignment | ||
Range on Protein: 288-349
Range on HMM: 261-316/328.0
GKPGPMVVHCSAGVGRTGTFITIdtMIMKIDAEGIVDIFNFvrgMRFCRNYMVQTaSQYDFL
| ..||| ||.|||||.|. .|| .. . .|.|| .| . | ||
kaeGaiavhCkaGLGrtGtLiac..ylmkhyrftaaeaiaw...lricrPGsvig.pqqkfl
|
|||||||||
DSPc | Dual specificity phosphatase, catalytic domain | 545-638 | 3.4e-06 | 22.0 | Pfam-A | 34-128 (133) | alignment | ||
Range on Protein: 545-638
Range on HMM: 34-128/133.0
SRTITHFQYINWPSTS-CPKEATSMIDLVADVVRiQRKSGNGPITVHCSDGLGRTGTFCAMFTVL-ERLKAEQVIDVFSTVKTLRIQRPGFVNDID
... ....|.. | .. .. .. . .... . .. .. . ||| |. |..|..... ..|.... ..... . .. ||. .
aikkseieylripvedetetkiskeleeavefie.kaeqkgkkvlVHCqaGisRSatliiaYlmktknlslneAyefvkerrskispnagflrqLl
|
|||||||||
DSPc | Dual specificity phosphatase, catalytic domain | 545-638 | 3.4e-06 | 22.0 | In-house | 34-128 (133) | alignment | ||
Range on Protein: 545-638
Range on HMM: 34-128/133.0
SRTITHFQYINWPSTS-CPKEATSMIDLVADVVRiQRKSGNGPITVHCSDGLGRTGTFCAMFTVL-ERLKAEQVIDVFSTVKTLRIQRPGFVNDID
... ....|.. | .. .. .. . .... . .. .. . ||| |. |..|..... ..|.... ..... . .. ||. .
aikkseieylripvedetetkiskeleeavefie.kaeqkgkkvlVHCqaGisRSatliiaYlmktknlslneAyefvkerrskispnagflrqLl
|
|||||||||
PTPc_motif_SM00404 | 549-624 | 5.8e-06 | 21.2 | In-house | 45-121 (140) | alignment | |||
Range on Protein: 549-624
Range on HMM: 45-121/140.0
THFQYINWPSTS-CPKEATSMIDLVADVVRiQRKSGNGPITVHCSDGLGRTGTFCAMFTVL-ERLKAEQVIDVFSTVK
.||... | .. . .| |.|... . .. .| . ||| |. |..|..... . |.......... .
sgfqilqiplddnekdklskyldkvldfie.naekkggkvlVHCqaGvSRSatliiaYlmryrqlslaeayefvkerR
|
|||||||||
Ig_3 | Immunoglobulin domain | 2-53 | 6e-06 | 18.4 | Pfam-A | 22-75 (75) | alignment | ||
Range on Protein: 2-53
Range on HMM: 22-75/75.0
CESTGTP-APTISWH-KEGMILEEPDYVQFNDGSLYITNTKLKDQGHFIVRATN
|...|.| .||||| .....|. ... ....| |.... .| | . . |.|
CsaeggpppptisWyietppelqgsegssssestLtissvtsedsGtYtCvasN
|
|||||||||
subfamily_PTEN_pd | Subfamily PTEN | 275-350 | 7.9e-06 | 21.0 | In-house | 98-173 (184) | alignment | ||
Range on Protein: 275-350
Range on HMM: 98-173/184.0
LLSFQKRVRNHHKGKP-GPMVVHCSAGVGRTGTFITIdTMIMKIDAEGIVDIFNFVRGMRFCRNYMVQTASQYDFLH
| .. . .... . .. .|||| || ||||. |. .. . | .. .. .|. . |. || ...
leeivediekwleedkknvvvvHCkaGkGRtGvliva.yllkslllekaeealelfaeaRtknkkgvtiPsqrRYve
|
|||||||||
subfamily_PTPDC1_pd | Subfamily PTPDC1 | 258-350 | 8.8e-06 | 20.3 | In-house | 85-169 (182) | alignment | ||
Range on Protein: 258-350
Range on HMM: 85-169/182.0
YHFLVWPDHGVPQYATpLLSFQKRVRNHHKgkPGPMVVHCSAGVGRTGTFITIDTMI-MKIDAEGIVdifNFvrgMRFCRNYMVQTASQYDFLH
.. . |.|.||. . .| | | . | . ||| || |||| |. . ...|| . .. .| | .|| .| ....
vynfgwkDygvasler.iLdivkvvafalq..egkvavhChaGlGrtGvliacylvyakrltaekai...kl...vrskrpksiqtreqvelvk
|