Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 653-944 | 7.8e-104 | 341.6 | In-house | 2-288 (290) | alignment | ||
Range on Protein: 653-944
Range on HMM: 2-288/290.0
VKLSEFADHIElLNKSNGGKGFKSEFQRLQNFGHLFSTEVANCSENKKRNRFKTILPYDNNLLTLRPISSRGDCSHSYINASYIDGYKKKHQFIATQGPL
.....|..... ....| .||...|..|... . ....|...|.||..|||..|..||.| .||||||.. ||...||||.||.|||.|.|.||||||.
ipvdkfgefva.nghakgnegfrnqfkmldsgesehtvtvgltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgykekkqyiatqgpv
PQTLVDFWRLIWQEDICCILMMLSITSDGGiVRCQQYWPDAiGVAAfYGPFKIIVegINDNKVSEERIIKLSMTSSSSSdNSHKTIHHYLFKCWPDHG-V
..||||||.|||||....|.|...|...| |.|||||||. ...| ||.|.| . .|.....|....||......|. ........| ...|...| |
sntlvdFWkliwqekvtiivmltniieegk.vkCqqYWpds.dtka.ygefsikl..lneetlneyierklevknknsa.gakqsvtqyqitnwdstgkv
PATPTSTHSFYEQIK-MWLDLPPPVLIHCSGGIGVTGMLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEAFYTIGK
... |......|..| .. . ....|||...|...........|.. ..|..||.......|.|.....||..|||......|...... .
tnpqtillvieemyktqrkrgntsivvHCSdtvgrsavfcaaattinkcktegvidvfqvlksqRiqkpgsvqtvqqyqgifqivltyldsfet
|
|||||||||
subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 962-1237 | 2.7e-94 | 310.3 | In-house | 13-289 (290) | alignment | ||
Range on Protein: 962-1237
Range on HMM: 13-289/290.0
HDEILNMNRYEAHYKALQVlTVKPNSVLRNFGLSNLPLVRSDLYLPPDEYRVVLNKKTED------FIHASYINGYQEARSFIVAESPTKLTAANFWSMI
.... .........|.|.. . ....| .... || .| |.. ....|..|..|...... .|.|.||.||.|....|....|.. |...||..|
nghakgnegfrnqfkmlds.gesehtvtvgltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgykekkqyiatqgpvsntlvdFWkli
VKNKCSVIVMLCDIVEMEVDTCYQYWPATyDSERhFDFYRIK-HHEMNIDnYYTQTILRVLDTQAGeEQTIILIQLPLSNIVSDElSHTERVGILSAIQE
...|...||||..|.|.. ..|.||||.. |... .. ..|| ..|.... .|... |.| ..... ... ...|. ..|. |.. ..|.. .||..|.|
wqekvtiivmltniieegkvkCqqYWpds.dtka.ygefsikllneetln.eyierklevknknsa.gakqsvtqyqitnwdstg.kvtnpqtillviee
IEKIQRKTGNNPILVHCSDTVSRSGVFCVLYTSIQQMKIEQQVNIYEILYNMRTCKPGLITTPVQYKMVYLLLMRYVEEFEAY
..|.|||.||..|.|||||||.||.|||...|.|...|.|........|...|..|||...| .||.... ....|...||.|
myktqrkrgntsivvHCSdtvgrsavfcaaattinkcktegvidvfqvlksqRiqkpgsvqtvqqyqgifqivltyldsfety
|
|||||||||
subfamily_PTPRD_pd | Subfamily PTPRD | 653-979 | 7.5e-83 | 274.0 | In-house | 5-320 (564) | alignment | ||
Range on Protein: 653-979
Range on HMM: 5-320/564.0
VKLSEFADHIELLNkSNGGKGFKSEFQRLQNFgHLFSTEVANCSENKKRNRFKTILPYDNNLLTLRPIssRGDCSHSYINASYIDGYKKKHQFIATQGPL
.. .|...|.. |. .|.. |..|...... . |..|.|| ..||..||.. |..||.. |... .|| . |||||.||||.|....|||||||
ipvaelkehvaklk.ansdlkfeeeykkieeg.qqftweaankpaNkaKNRyanivaYdhsRVvLskv..egdegsDYINAsfidgyrkrkayIAtqgPl
PQTLVDFWRLIWQEDICCILMMLSItSDGGIVRCQQYWPDAiGvAAFYGPFKiiVEGINDNKVSEERIIKLSMtSSSSSDNShKTIHHYLFKCWPDHGVP
..|. ||||..|......| |. .. .. | |.|..|||. | . || .. |. . ..... | .... . ..|..| ...... | |||||||
aetiedFWRmvweqnsstiVmltkl.eEkgkvkchkYWPek.g.tetygelt..Vtleeeeeladyeirtfkl.kkkksses.reVrqFhFtsWPdhgvp
ATPTSTHSFYEQIKMWLD-LPPPVLIHCSGGIGVTGMLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEAFYTiGKESITPSN
..|| .. .... . |...||| |.| ||. | | . .|. . . ||.. .|...|.|| |.||||||.|.|...||| |..... .|
esatslLdlirkvralnepdagPivVhCSaGVGRTGtfividamlerikeektvDiyqyvkalrkqRnamVqteeQYiFiheailealac.gntevesen
LQLIVKRLGKHDEILNMNRYEAHYKALQ
|. ...| . .| .| .|. .. |.
lkqhlqkLaeveedtemtgleleFqrLa
|
|||||||||
0051299 | (Phosphotyrosine protein) phosphatases II | 652-939 | 6.2e-80 | 264.0 | In-house | 4-286 (288) | alignment | ||
Range on Protein: 652-939
Range on HMM: 4-286/288.0
YVKLSEFADHIELLNkSNGGKGFKSEFQRLQNFGHLFSTEVANCSENKKRNRFKTILPYDNNLLTLRPISSrgDCSHSYINASYIDGYKKKHQFIATQGP
....|...... | || .|.. ||..|... . ... .|. ||...||.. |||||.. |..... . ...||||||||||..|..|||||||
eisveellklvlkll.angltglleefeellsllpdltlsaallpenleknRysdilpydhsRVkLsvldg..vegsdYinAsyidgynlkrkfIatqgP
LPQTLVDFWRLIWQEDICCILMMLSITSdGGIVRCQQYWPDaiGVAAFYGPFKIIVEGINDNKVSEERIIKLSMTSSSSSDNSHKTIHHYLFKCWPDHGV
||.|. ||||..|.... .| |. ... | . | ||||. | ||.... . .. | .... .. . |. ..|..|. .. ||||||
lpntvedFWrmvweqnvrvIvmltklve.lgrekcaqYwpl..ggsltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdhgv
PATPTSTHSFYEQIKMW-LDLPPPVLIHCSGGIGVTGMLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEAF
| .|.. .|..... . . ..||..||| |.| ||..| . . .|| . .|||||. .|...|.||..|.||.|||.||...|||..
pdspellldflrlvrkalasgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyealleyl
|
|||||||||
0050432 | (Phosphotyrosine protein) phosphatases II | 658-941 | 7e-79 | 260.7 | In-house | 28-301 (308) | alignment | ||
Range on Protein: 658-941
Range on HMM: 28-301/308.0
FADHIELLNKSNGGKGFKSEFQRLQNFGHLFSTEVANCSENKKRNRFKTILPYDNNLLTLrpissrgDCSHSYINASYIDGY--KKKHQFIATQGPLPQT
| ..||.| .. .... ||..|... |....||. |||..||.| |||||.. | | ...||||||.||| |....|||||||||.|
vldllkllekaldlglleeefeellsvkplleysvallpenkdkNrykdilpydhsRVkl.......degsdYInAsyvdgyssklprkfIatqgPlpnt
LVDFWRLIWQEDICCILMMLSITSdGGIVRCQQYWPDAIG-VAAFYGPFKIIVEGINDNKVSEERIIKLSMTSSSSSdnshKTIHHYLFKCWPDHGVPAT
. ||||..|.... .| |. ... |.. | ||||. .| ||.|.. . . .. | ..|...... | .|..|. .. |||||||
vedFwrmvweqnvrvIvmLtklve.ngrekcaqYwplelgggsleygkftvtllseevlddytvrtleltnlgdges....rtvthfhytnWpdhgvPps
PTSTHSFYEQIKMWLdLPPPVLIHCSGGIGVTGMLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEAFYT
|.. .|.|... .| ..|...||| |.| || .| . . .|| .||||| .|.|.|.||..|.||.|||.|....||| ...
peilldflelvrksl.pggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylflyralleylkl
|
|||||||||
0047943 | (Phosphotyrosine protein) phosphatases II | 663-938 | 1.9e-77 | 255.7 | In-house | 3-271 (273) | alignment | ||
Range on Protein: 663-938
Range on HMM: 3-271/273.0
ELLNKSNGGKGFKSEFQRLQNFGHLFSTEVANCSENKKRNRFKTILPYDNNLLTLrpissrGDCSHSYINASYIDGYKKKHQFIATQGPLPQTLVDFWRL
||.|..| .... ||..|... .|....||. |||..||.| |||||.. | || ...||||||.|||..|..|||||||||.|. ||||.
lllekllgltllleefelllslkplltysvallpenkdknrykdilpydhsrvkl......gdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrm
IWQEDICCILMMLSITSDgGIVRCQQYWPDAIGV-AAFYGPFKIIVEGINDNKVSEERIIKLSMTSssssDNSHKTIHHYLFKCWPDHGVPATPTSTHSF
.|.... .| |. ..... | . | ||||. | ||.|.. . ... .. | ..|.... .. .|..|.... |||||||....| .|
vweqnvrviVmLtelvel.grekcaqYwpleggelsltygkftvtllseetkddytvrtleltnlg....tgesrtvthfhytgwpdhgvppslesllef
YEQIKMWLD---LPPPVLIHCSGGIGVTGMLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEA
.|... .| ..||..|||.|.| ||..| . . ..| .||||| .|...||||..|.||.|||.|....|||
ielvrkalealpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyealley
|
|||||||||
0036941 | (Phosphotyrosine protein) phosphatases II | 662-941 | 2e-77 | 255.7 | In-house | 3-279 (297) | alignment | ||
Range on Protein: 662-941
Range on HMM: 3-279/297.0
IELLNKSNGGKGFKSEFQRLQNFGHLFSTEVANCSENKKRNRFKTILPYDNNLLTLrpissrGDCSHSYINASYIDGYKKKHQFIATQGPLPQTLVDFWR
. ||.|... ....||..|... .|.|..||. ||...||.| |||||.. | .| ...||||||.|||. |..|||||||||.|. ||||
lkllekllflalllkefeellpllllgslsvallpenleknRykdilpydhtRVkl......ddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWr
LIWQEDICCILMMLSITSDgGIVRCQQYWPDAIGVAAFYGPFKIIVEGIND--NKVSEERIIKLSMTssssSDNSHKTIHHYLFKCWPDHGVPATPTSTH
..|.... .|.|. . ... | . |.||||. .| ||.|.. . ... .. | .....| .. ..|..|. .. ||||||| .|.|
mvweqnvtvIvmltelvel.grekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdt....gngesrtvthfhytgwpdhgvpespasll
SFYEQIKMWLD---LPPPVLIHCSGGIGVTGMLISIMIGIEQGL---STGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEAFYT
.|.|... .|. ..|||.|||.|.| .|..| . . ..| .||||. .|.|.|.||....||.|||.|....||| ...
dfielvrkvlkllpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallellkk
|
|||||||||
0040438 | (Phosphotyrosine protein) phosphatases II | 657-943 | 7e-76 | 250.8 | In-house | 4-280 (317) | alignment | ||
Range on Protein: 657-943
Range on HMM: 4-280/317.0
EFADHIELLNKSNGgKGFKSEFQRLQNFGHLfSTEVANCSENKKRNRFKTILPYDNNLLTLRPISSrgDCSHSYINASYIDGYKKKHQFIATQGPLPQTL
.. .....|.||. .....||..|... . ...||. |||..||.. |||||.. | |... | ...||||||.||...|..|||||||||.|.
dlllalldllksdf.talleefedllslkld.tysvaelpenkdknrypdilpydhsRVkLsplgg..dldsdYInAsyvdgpnlkrkfIatqgPlpntv
VDFWRLIWQEDICCILMMLSITSdGGIVRCQQYWPDaiGVAAFYGPFKIIVEGINDnkvsEERIIKLSMTS--SssSDNSHKTIHHYLFKCWPDHGVPAT
||||..|......|.|. . . | . |.||||. | ||.|.. . .. .. |. . .. . |. . |..|. .. ||||||| .
edFwrmvweqgvtvivmLtelee.lgrekcaqYwpl..getltygdftvtllseee....lagitlrtlevedl..gdsesrtvthfhytgWpdhgvpps
PTSTHSFYEQIKMWLDL-PPPVLIHCSGGIGVTGMLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEAFYTIG
|.. .| |... .|. . |||.|||.|.| ||..| . . .|| .||||| .|...|.||....||.|||.|....||| ... .
pdllldfleavrealedpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleylkrkl
|
|||||||||
0046845 | (Phosphotyrosine protein) phosphatases II | 673-941 | 2.4e-75 | 248.8 | In-house | 1-276 (284) | alignment | ||
Range on Protein: 673-941
Range on HMM: 1-276/284.0
GFKSEFQRLQNFGHLF--STEVANCSENKKRNRFKTILPYDNNLLTLRPISSRgDCSHSYINASYIDGY-----KKKHQFIATQGPLPQTLVDFWRLIWQ
|.. ||..|... . . |..||. ||...||.| |||||.. |...... . ...||||||.||| ..|..|||||||||.|. ||||..|.
gleeefeellsltvklllslsvallpenlsknRykdilpydhsRVklksldgd.ledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvwe
EDICCILMMLSITSdGGIVRCQQYWPDAiGVAAFYGPFKIIVEGINDNKVSEERIIKLSMTsssSSDNSHKTIHHYLFKCWPDHGVPATPTSTHSFYEQI
... .| |. .... | . | ||||. | ||.|.. . .. .. | ..|... . .. ..|..|. .. |||||||..|.. .|....
qnvrvIVmltelve.ngrekcaqYwple.gevltygdftvtllseevkddytvrtleltnl...gytgesrtvthfhytswpdhgvppspedlleflrlv
KMWLDL---PPPVLIHCSGGIGVTGMLISIMIGIEQGLSTG---GVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEAFYT
. .|. ..|...|||.|.| ||..| ... .|| .| |||| .|...|.||..|.||.|||.||...|||....
rellenlpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleylkl
|
|||||||||
0039614 | (Phosphotyrosine protein) phosphatases II | 656-939 | 1.1e-73 | 243.6 | In-house | 16-289 (297) | alignment | ||
Range on Protein: 656-939
Range on HMM: 16-289/297.0
SEFADHIELLNKSNGGKGFKSEFQRLQNFGHlfSTEVANCSENKKRNRFKTILPYDNNLLTLRPISSRgDCSHSYINASYIDGYKK-KHQFIATQGPLPQ
.. | . ||.| |. ... ||..|... . ....|. |||..||.| |||||.. | |. .. | ...||||||.|||.. ...|||||||||.
lsvldlllllekansktllllefeellslkp..dysiallpenkdknrykdilpydhsrvklkpedgv.dldsdYinAsyvdgydlltrkfIatqgPlpe
TLVDFWRLIWQEDICCILMMLSITSDGGivRCQQYWPDAIGvaaFYGPFKIIVEGINDNKVSEERIIKLSMtsssssDNSHKTIHHYLFKCWPDHGVPAT
|. ||||..|.... .|.|. . . .| |.||||. | ||.|.. . .. .. | ..... .. .|..|... .||||||| .
tvedFwrmvweqgvtvivmLtklvelgr..kcaqywpeegg...tygdftvtllkvehldgytvrtlevtn......ngesrtvthfqytgwpdhgvpps
PTSTHSFYEQIKMWLD---LPPPVLIHCSGGIGVTGMLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEAF
... .|.|... .| . |||.|||.|.| ||..| . . .|| ..||||| .|...|.||....||..||.|....||| .
lellleflelvrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydallell
|
|||||||||
0045450 | (Phosphotyrosine protein) phosphatases II | 664-939 | 4.4e-73 | 242.0 | In-house | 19-304 (307) | alignment | ||
Range on Protein: 664-939
Range on HMM: 19-304/307.0
LLNKSNGGKGFKSEFQRLQNFGH--LFSTEVANCSENKKRNRFKTILPYDNNLLTLRPISSRgDCSHSYINASYI--------DGYKKKHQFIATQGPLP
||.. .. |.. ||..|... . |.....|. |||..||.| |||||.. | ..... . ...||||||. |||..|..|||||||||
llllldfltgllkefekllsvtvfllgeysiallpenkdknrykdilpydhtRVklssldgs.ledsdYiNAsyvrvpllllldgydlkrkfIatqgPlp
QTLVDFWRLIWQEDICCILMMLSITSDgGIVRCQQYWPDAiGVAAFYGPFKIIVEGINDNKVSEERIIKLSMTsssSSDNSHKTIHHYLFKCWPDHGVPA
.|. ||||..|.... .|.|. . . . | . | ||||| | ||.|.. . ... . | ...... . .. . |..|. ...|||||||
etvedFwrmlweqgvtvivmltelvel.grekcaqywPde.geeltygnftvtllseehldgytvrtlevtdl...dgtgesrtvthfhytgwpdhgvpp
TPTSTHSFYEQIKMWLD---LPPPVLIHCSGGIGVTGMLISIMIGIEQGLSTGG---VDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEAF
.. .. .|.|... .|. . |||.|||.|.| ||..| . . ..|. ..| ||. .|...|.||....|..|||.|....||| .
sfeelldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeallell
|
|||||||||
subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 653-961 | 7.9e-72 | 237.0 | In-house | 4-304 (305) | alignment | ||
Range on Protein: 653-961
Range on HMM: 4-304/305.0
VKLSEFADHIELlNKSNGGKGFKSEFQRLQNFGHlfSTEVANCSENKKRNRFKTILPYDNNLLTLRPISSRGdcSHSYINASYIDGYKKKHQFIATQGPL
. |...| .|. .... ||.. ... |.. .. |..| . ..||..||.| | ..|.. . |.. .| . . ||||||.||||.|...|..||||
ialddlaayike.arvysdkgleaqykslyeeee..sidvgkkeankaknrlkeitlldddriiltekesld..dsdyinasyvdgykrkkkyivaqgPl
PQTLVDFWRLIWQEDICCILMMlSITSDGGIVRCQQYWPDAIGVAAFYGPFKIIVEGINDNKVSEERIIKLSMTSSsssDNSHKTIHHYLFKCWPDHGVP
..|..||||||..| . |.|. . . .|| .|.||||.... .|.|..... . . || .|.|. .. |. .|. .| . |||||||
kntvadfWrliveekvstivml.tklveggkdkCrqYWpesktekkefgefsvelksektasdyieRklkisiede...dkesrtvlqyqltdWPdhGvp
ATPTSTHSFYEQIKMWLDL--PPPVLIHCSGGIGVTGMLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEAFyTIGKESITPS
..|| |...... |.|.||| |.| ||. |.. | .|. . |||. .....||.||.|.|| .||.|.| .| | | |. || |
qfatsllslikrvqkdqkkdkgvpllVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkmvqtldqYvflhdaldeli.tcgdtsiigs
NLQLIVKRLGK
||.. |..| |
nlrarvnklkk
|
|||||||||
subfamily_PTPRB_pd | Subfamily PTPRB | 652-939 | 1.6e-71 | 235.7 | In-house | 6-285 (293) | alignment | ||
Range on Protein: 652-939
Range on HMM: 6-285/293.0
YVKLSEFADHIELLNKSNgGKGFKSEFQRLQNFGHLFSTEVANCSENKKRNRFKTILPYDNNLLTLRPISSrgDCSHSYINASYIDGYKKKHQFIATQGP
.||..|..|.. ... . .|. |...|...|. ....|. ..|...||.. |||||.. . | .... . . ||||.||.||. ...|||||||
piklekfeehvkkmkads.dlrfseeyeelkavgkdqavkaaelavnraknrytnilpydhsrvkLaalkd..esgsDYinanyipgynsprefiatqGP
LPQTLVDFWRLIWQEDICCILMMlSITSDGGIVRCQQYWPDAIgVAAFYGpfKIIVEGINDNKVSEERIIKLSMTSssssDNSHKTIHHYLFKCWPDHGV
||.|. ||||..|.. |.|. . ..| |.|..|||. . .|| .| |. ........ | .|... .........| |. ||||||
lpetvddfWrmvwekkssiivml.tqlvekgkvkCeeYWPade.epvlyG..dikvtlvaeeeledwvirelkiek....ekeerkvrqyhftsWpdhgv
PATPTSTHSFYEQIKMWL---DLPPPVLIHCSGGIGVTGMLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEAF
| .... .| .... .. |...||| |.| || .|.. ... .. ||...|| ..|..|....|||.|| |.| ..|. .
PektktlldfvrtvreaiektaskrPivvhCsaGvGRtGtfialdrllqaieeedyvdifgivaelReeRnllvqtekqYifihqcvldll
|
|||||||||
0043336 | (Phosphotyrosine protein) phosphatases II | 656-937 | 6.5e-71 | 234.3 | In-house | 5-275 (278) | alignment | ||
Range on Protein: 656-937
Range on HMM: 5-275/278.0
SEFADHIELLnKSNGGKGFKSEFQRLQNFGHlFSTEVANCSENKKRNRFKTILPYDNNLLTLRPISSrgDCSHSYINASYIDGYKKKHQFIATQGPLPQT
........ | . |. .... ||..|..| . .....|. |||..||.| |||||... | .... | ...||||||.|||.....|||||||||.|
kdllkallel.llnlktllllefeellsfkl.dtysiallpenkdknrykdilpydhsrvklsllgg..dldsdYinAsyvdgynvprkfiatqgPlpet
LVDFWRLIWQEDICCILMMLSITSdGGIVRCQQYWPdaiGVAAFYGPFKIIVEGINDNKVSEERIIKLSMtsssSSDNSHKTIHHYLFKCWPDHGVPATP
. ||||..|.... .|.|. . . | | |.|||| | ||.|.. . ... .. | ..... |. .|..|| ...||||||| ..
vedFwrmvwelgvttivmLtelve.lgrvkcaqYwp...ggsltygdftvtllkeehlddytvrtlevtn....lgdgesrtvthyhylgwpdhgvpesl
TSTHSFYEQIKMWLD-LPPPVLIHCSGGIGVTGMLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLE
.. .|..... .|. . |||.|||.|.| ||..| . . .|| ..||||. .|...|.||....||..||.|....|||
sllldflkavrealedsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyealle
|
|||||||||
subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 654-964 | 1.3e-69 | 229.8 | In-house | 6-307 (319) | alignment | ||
Range on Protein: 654-964
Range on HMM: 6-307/319.0
KLSEFADHIELLNKsNGGKGFKSEFQRLQNFGHLfSTEVANCSENKKRNRFKTILPYDNNLLTLRPISSrgDCSHSYINASYIDGYKKKHQFIATQGPLP
.. |...... |.. .| .... ||. |.. . ... |. ||||.||.. ||.||. ..| .. . |||||.||||.....|||||.||
evqeLkerlkalas.tgetllekefkllkeavnd.tfdsaskeenkkknryqnilaydrtrvvlseldg..vegsdyinasfidgyqerekfiatqaPle
QTLVDFWRLIWQEDICCILMMLSItSDGGIVRCQQYWPDAIgvAAFYGpfKIIVEGINDNKVSEERIIKLSMtSSSSSDNSHKTIHHYLFKCWPDHGVPA
.|. ||||..|.|.. ...|. . .. . |....|||.. || ..||. .... .. | ||.. ||. ... |. .. ||||.||
ntiedfWrmvWeeessivvmltkl.veklkvklkkywpeen..feeyG..rlivtleeeeeledyiirklkl.nkkssevetRevkhfqyteWpdhdvPe
TPTSTHSFYEQIKMWLD--LPPPVLIHCSGGIGVTGMLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEAFyTIGKESITPSN
. || ....|. . |. .||| |.| || | . . .|. | .|| .|...| || |.|..|||.|....|||| ..|. | .
katslldllkrirksrektqsgPivvhCsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyealleav.eagdteievqd
LQLIVKRLGKHDE
|. .|.| ...
lrdrlkqlaekva
|
|||||||||
DSPc_SM00195 | 674-939 | 1.4e-69 | 229.7 | In-house | 2-262 (263) | alignment | |||
Range on Protein: 674-939
Range on HMM: 2-262/263.0
FKSEFQRLQNFGHLFSTEVANCSENKKRNRFKTILPYDNNLLTLRPISSRgdCSHSYINASYIDGYKKKHQFIATQGPLPQTLVDFWRLIWQEDICCILM
.| ||..|.. . .|. |. ..||..||.| |||||.. | .. .. ...||||.||.|..||...||||||||.|. ||||..|.|.. .|.|
lkeefekleestspketteaekkknksknRyknilpydhtrVklkkeekk..egsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivm
MLSITSDgGIVRCQQYWPDAIGVAAFYGpfKIIVEGINDNKVSeERIIKLSMTSSSSSDNSHKTIHHYLFKCWPDHGVPATPTSTHSFYEQIKMWLD-LP
. . . | .|..|||. .| .| || |. .. .|.. . ||. .. . .. ......| .| ||||||| ...|. ......| . .
lteeeen.gkekcdrywpeesggketfg..kisvklvevekkk.deiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkkskstss
PPVLIHCSGGIGVTGMLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEAF
.|...||| |.| ||....| | ... .. ||. .||...|.||..|.||.|||.|.. ..||..
gpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi
|
|||||||||
PTPc_SM00194 | 674-939 | 1.4e-69 | 229.7 | In-house | 2-262 (263) | alignment | |||
Range on Protein: 674-939
Range on HMM: 2-262/263.0
FKSEFQRLQNFGHLFSTEVANCSENKKRNRFKTILPYDNNLLTLRPISSRgdCSHSYINASYIDGYKKKHQFIATQGPLPQTLVDFWRLIWQEDICCILM
.| ||..|.. . .|. |. ..||..||.| |||||.. | .. .. ...||||.||.|..||...||||||||.|. ||||..|.|.. .|.|
lkeefekleestspketteaekkknksknRyknilpydhtrVklkkeekk..egsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivm
MLSITSDgGIVRCQQYWPDAIGVAAFYGpfKIIVEGINDNKVSeERIIKLSMTSSSSSDNSHKTIHHYLFKCWPDHGVPATPTSTHSFYEQIKMWLD-LP
. . . | .|..|||. .| .| || |. .. .|.. . ||. .. . .. ......| .| ||||||| ...|. ......| . .
lteeeen.gkekcdrywpeesggketfg..kisvklvevekkk.deiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkkskstss
PPVLIHCSGGIGVTGMLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEAF
.|...||| |.| ||....| | ... .. ||. .||...|.||..|.||.|||.|.. ..||..
gpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi
|
|||||||||
subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 653-966 | 4.3e-69 | 228.0 | In-house | 2-306 (318) | alignment | ||
Range on Protein: 653-966
Range on HMM: 2-306/318.0
VKLSEFADHIELLNKsNGGKGFKSEFQRLQNFGHLFSTEVANCSENKKRNRFKTILPYDNNLLTLRPISsrGDCSHSYINASYIDGYKKKHQFIATQGPL
........|.. |.. .| ...|..||. . ... .. . ||..||. ||.||. |.... |. . ||||.|||||..|...||.|.||
isvedleshvrrlre.sGelllseeyerlsrseetvtslkslepvnkaknryanilaydhtrvkLqmle..geegsDyinanyidGyrrkkayiaaqaPl
PQTLVDFWRLIWQEDiCCILMMLSITSDGGIVRCQQYWPDAIgvAAFYGpfKIIVEGINDNKVSEERIIKLSMTSssSSDNSHKTIHHYLFKCWPDHGVP
|.|. ||||..|. . .....||. ... | .....|||. . || |. || .. ..|. . ....| . ....... | . |||.|||
petieDfWrmvWeqn.savivmltqeeergkakvhryWPskg..srsyg..klvvelkeevelsdyvlrefkvtr..teeeesrqvrqyhytsWpdegvp
ATPTSTHSFYEQIKMWL--DLPPPVLIHCSGGIGVTGMLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEAFYTiGKESITPS
. ..| .. |.. . |...|||.|.| ||. | . | .|. . |||. .|...|.|| |.|||.||.|.. ||||| . |. . |
esgaslldlvrqvskaqqksgagpivvhCsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqtedqyefiydvllealas.gdtevdas
NLQLIVKRLGKHDEIL
.|. ...| ..|
dlrsrirelreqdpes
|
|||||||||
subfamily_PTPRK_pd | Subfamily PTPRK | 654-961 | 4.6e-68 | 224.4 | In-house | 5-298 (314) | alignment | ||
Range on Protein: 654-961
Range on HMM: 5-298/314.0
KLSEFADHIELLNKSNgGKGFKSEFQRLQNFghlfsTEVANCSENKKRNRFKTILPYDNNLLTLRPISsrGDCSHSYINASYIDGYKKKHQFIATQGPLP
. . ..| ||.... | ||| |.. | . ..|. ||...||.. ||.||. . .| .| || | ||||..||.||. ..||.|||||.
rvadllqsiallkrae.gygfkeeyeslfeg.....wdaakkdenreknrsgdilaydrsrvflitid..gdpssdyinaalidsykrpaafivtqgPlq
QTLVDFWRLIWQEDICCILMMLSItSDGGIVRCQQYWPDAIGVaafYGPFKIIVEGINDNKVSEERIIKLsmTSSSSSDNSHKTIHHYLFKCWPDHGVPA
.|. |||||...|. ..|.|. . . | |.| .|||. | ||..|. . . .. || .. . .. . . ....... | ||||.||
etvkdfWrlvydencasivmltel.vevgrvkClkyWPedtev...ygdikvelvetellaelvvrifrv..eklargqeeirevrqfqflgWpdhdvPv
TPTSTHSFYEQIKMWLDL-PPPVLIHCSGGIGVTGMLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEAFYtIGKESITPSNL
|. .. ..|.. . ....||| | | ||. | | | .. | ||| .| ..||...||..|||||.|.. |.||| |. .| |..
satgllklvrrvkksqeeeaGrivvhCsaGaGrtGtfiaidivldmieregvvdvfnavktlrsrkvnmveteeqykfiydvileacl.cgetaipvsef
QLIVKRLGK
. . . .
kalylesir
|
|||||||||
subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 667-941 | 6.4e-66 | 217.3 | In-house | 16-281 (288) | alignment | ||
Range on Protein: 667-941
Range on HMM: 16-281/288.0
KSNGGKGFKSEFQRLQNFGHLFSTEVANCSENKKRNRFKTILPYDNNLLTLRPISSRGDcsHSYINASYIDGYKKKHQFIATQGPLPQTLVDFWRLIWQE
. .. .||..|.. | .... |..... ..|.|.||.. ||||| . . |. . |||||||||.|||...|||||||..|. |||.|....
sarnrtgfseeynsLaalektksvtagrlavnakknRyrnilpyDekrvklkkleeeag..aDYinasyidgekkkkkyiatqgPladtvndfWelvyen
DICCILMMLSITsDGGIVRCQQYWPDAiGVAAFYGPFKIIVEGINDNKVSEERIIKLSmtssssSDNSHKTIHHYLFKCWPDHGVPATPTSTHSFYEQIK
.. |.|. .. .|| .|..||||| . || ..... . .. . .| . | .... .|..| .. |||||||. . . .|.|
ktstivmltelv.eggktkCeeYWPda.dkpknyGsvtvtlveskeledfvlrkllle......kkkteleitqyqylaWpdhgvPeskapllellrqvk
MWLDLP-PPVLIHCSGGIGVTGMLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEAFYT
. . |...||| |.| || |.. |.. .. .||...|.|.| ||....||..||.|.. |||. .
vanqadtgpiivhCsaGvGrtgtFialdalidaveeedyiDvagtvaklRkqRallvqtlkqYefiyevllsliee
|
|||||||||
0045098 | (Phosphotyrosine protein) phosphatases II | 674-939 | 2.2e-65 | 216.1 | In-house | 9-272 (278) | alignment | ||
Range on Protein: 674-939
Range on HMM: 9-272/278.0
FKSEFQRLQNFGHLFSTEVANCSENKKRNRFKTILPYDNNLLTlrpissrgdcshSYINASYIDGYkkKHQFIATQGPLPQTLVDFWRLIWQEDICCILM
...||..| |. . ..|. .|...||.| |||||.. |||||||||| ...|||||||||.|. ||||..|...| .|.|
lllefefllllgipseitpalylgnldknRykdilpydhsrVk............dYINAsyidgy..pkkfIatqgPlpstvadfwrmlwelgitvivm
MLSITSDGgIVRCQQYWPDaiGVAAFYGPFKIIVEGINDNKVSEERIIKLSMTSSSSSDNSHKTIHHYLFKCWPDHGVPATP--TSTHSFYEQIKMWLD-
. . . .| . | ||||. | ||.|.. .. . .. | ... ... .|. ...|. ...||||||| .| .| ...|.|. .|.
ltelvelg.rekcaqywpe..ggsltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkl
-------------LPPPVLIHCSGGIGVTGMLISIMIGIEQGlsTGGVDVMAIVNKMRSQRMN-MIQTEEQYQFVHYVLLEAF
. |||.||| |.| ||.|. ... .|. ||||. .|...||||.. ..|..|||.|....||| .
laslllsslllldsggpvlVHCsaGvgRtGtlvaaylmlell..eggvdlleavkelrsqRpglavqnleqyrflyefllell
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 698-937 | 2.6e-65 | 215.5 | Pfam-A | 1-235 (235) | alignment | ||
Range on Protein: 698-937
Range on HMM: 1-235/235.0
NKKRNRFKTILPYDNNLLTLrpiSSRGDCSHsYINASYIDGYKKKHQFIATQGPLPQTLVDFWRLIWQEDICCILMMLSITSDgGIVRCQQYWPDAIGVA
|||.||.|.|||||.. | ..... | ||||.|..|||.|..||||||||..|. ||||..|||.. .| |. | . | . |.||||.. .
nkkknRykdilpydktrvkl...kgsegpsd.YInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleek.grekcaqYwpeeeees
AFYGPFKIIVEgiN-DNKVSEERIIKLSMTSSSSSDNSHKTIHHYLFKCWPDHGVPATPTSTHSFYEQIKMWL-DLPPPVLIHCSGGIGVTGMLISIMIG
|| .|. .. . .. ..| ... ... ... ....... .. |||||||..|.| .. .... . . ||..||| |.| ||......|
ltygdikvelk..ekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldil
IEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLE
.|| ... |||. ||...|.||..|.|..|||.|.. ..||
leqleaeeevdvlqivkelRkqRpgmvqsleqYiflykaile
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 698-937 | 2.6e-65 | 215.5 | In-house | 1-235 (235) | alignment | ||
Range on Protein: 698-937
Range on HMM: 1-235/235.0
NKKRNRFKTILPYDNNLLTLrpiSSRGDCSHsYINASYIDGYKKKHQFIATQGPLPQTLVDFWRLIWQEDICCILMMLSITSDgGIVRCQQYWPDAIGVA
|||.||.|.|||||.. | ..... | ||||.|..|||.|..||||||||..|. ||||..|||.. .| |. | . | . |.||||.. .
nkkknRykdilpydktrvkl...kgsegpsd.YInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleek.grekcaqYwpeeeees
AFYGPFKIIVEgiN-DNKVSEERIIKLSMTSSSSSDNSHKTIHHYLFKCWPDHGVPATPTSTHSFYEQIKMWL-DLPPPVLIHCSGGIGVTGMLISIMIG
|| .|. .. . .. ..| ... ... ... ....... .. |||||||..|.| .. .... . . ||..||| |.| ||......|
ltygdikvelk..ekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldil
IEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLE
.|| ... |||. ||...|.||..|.|..|||.|.. ..||
leqleaeeevdvlqivkelRkqRpgmvqsleqYiflykaile
|
|||||||||
subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 662-941 | 4.2e-65 | 214.9 | In-house | 17-292 (298) | alignment | ||
Range on Protein: 662-941
Range on HMM: 17-292/298.0
IELLNKSNGGKGFKSEFQRLQNFGH---LFSTEVANCSENKKRNRFKTILPYDNNLLTLRPISsrGDCSHSYINASYIDGYKKKHQFIATQGPLPQTLVD
.. .|... |...|||||.. . ...|||. .||||.||. |...| |. .. .| |||||....||... |||||.||..|..|
laavkkkkkltgyalefqrlnsvsseieeeekevarkpenkkkNRyadiialdssRvvLeked..adeesdYiNAsflhaykgrnafiatqaPltetved
FWRLIWQEDICCILMMLSItSDGGIVRCQQYWPDAigVAAFYGPFKIivEGINDNKVSEERIIKLSMTSSSSSdnSHKTIHHYLFKCWPDHGVPATPTST
|||....||| .| |. .. . . .....|||| .. || ... . .... .. . || ....... ....... | |||.|||.. ||
FWrmvteedigtiVmltnl.eeldktkyhkywPde..gketygeitv..sllskeefadlivrklkvskkkee..kerevrqlhftsWpdkgvpenatsv
HSFYEQIKMWLDLPP--PVLIHCSGGIGVTGMLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEAFYT
. ...... ||...|| |.| .| | | .|. |||. .|. .| .|....|||||| |.... |||. .
ldllrkvrasqqqagnkpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavlealds
|
|||||||||
0040439 | (Phosphotyrosine protein) phosphatases II | 690-939 | 4.7e-64 | 211.7 | In-house | 3-246 (249) | alignment | ||
Range on Protein: 690-939
Range on HMM: 3-246/249.0
TEVANCSENKKRNRFKTILPYDNNLLTLRPISSrgDCSHSYINASYIDGYKKKHQFIATQGPLPQTLVDFWRLIWQEDICCILMMLSITSDgGIVRCQQY
..||. |||..||.. |||||.. | .... ..||||||||||. |..|||||||||.|. ||||..|...| .|.|. | . | . |.||
ysvallpenkdknrypdilpydhsrvklsilpg..lflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvel.grekcaqy
WPDaiGVAAFYGPFKIIVEGINDNKVSEERIIKLSMTssssSDNSHKTIHHYLFKCWPDHGVPATPTSTHSFYEQIKMWLD---LPPPVLIHCSGGIGVT
||. | || |.. . .. .. | ..|... |... |..|. . ||||||| .. .. .|.|... .|. . |||.|||.|.| |
wpl..ggsleygdftvtllsvevkddytvrtleltnl....ydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRt
GMLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEAF
|..| . . .|| ..|||. .|...||||....|..|||.|....||| .
GtfiaaylmleqlekelgvdleeavkllrsqRpgavqnpeqyrflyeallell
|
|||||||||
subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 667-939 | 1.4e-63 | 209.7 | In-house | 10-276 (281) | alignment | ||
Range on Protein: 667-939
Range on HMM: 10-276/281.0
KSNGGKGFKSEFQRLQNFGHLFSTEVANCSENKKRNRFKTILPYDNNLLTLRPISSRGdcSHSYINASYIDGYKKKHQFIATQGPLPQTLVDFWRLIWQE
..| .||..|.. |.. | ... .. ||...||.. | ||. .. | .. . ||||....|||.....||||||.|..||.||...|..
sqndnaGfieeyeklaaigvdntataskadenvlknrYsnivaYDatrvkvtpneenk..ntDYinanfvpgykgekeyiatqgPvPaslvafWqmvweq
DICCILMMlSITSDGGIVRCQQYWPDAIGvAAFYGPFKIIVEGINDNKVSEERIIKLSMTSssssdNSHKTIHHYLFKCWPDHGVPATPTSTHSFYEQIK
... | |. ..| ..| .|||| . || ... . .... . || .||...| . ...... .. |||||||||.. .| ....
kvsaivmv.treieagklkChrYWPddns.elkygdvtvkstaeeekatyierkfkleres.....getreveqlaytaWPdhGvPattkellefrkevl
MWL--DLPPPVLIHCSGGIGVTGMLISIMIGIEQGLST-GGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEAF
. |..|||| |.| || |.. ... .. .|| |.|...| .|. |.|| ||.||. ..|.|.
kltekktkaplvihCsaGvGrtGtyialDrlvkaveaeleeldvkavvaelrkernlmvqtvvqyefvykavldal
|
|||||||||
subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 961-1240 | 2.1e-63 | 209.0 | In-house | 12-287 (287) | alignment | ||
Range on Protein: 961-1240
Range on HMM: 12-287/287.0
KHDEILNMNRYEAHYKALQVLTVKPNSVLRNFGLSNLPLVRSDLYLPPDEYRVVLNKKTEDFIHASYINGYQEARSFIVAESPTKLTAANFWSMIVKNKC
.... . . .. .. |. .| ....| | .| .. |. |.||.|||.|... .|.| |..|.||.|.. ||.|||| || ||| .| ...
akghakgnegfknqftvleqvtqredevthniasqnkdknRltqilvpdnyrvllkgehpdyinavfidgykekkafiiaesPmfntarnfWkliddrnv
SVIVMLCDIVEMEVDTCYQYWPATYDseRHFDFYRIKHHEMNIDNYYTQTILRVLDTQA-GEEQTIilIQLPLSNIVSDElSHTERVGILSAIQEIEKIQ
..|||||. | . . |||||| . . |.|. . .. . |.. |.| .. |..|.. | . | | || || |.| | |
taivmlcqekendeevcyqyWpeeks..vvlGeyniellneevnagyierklevknknkagdkqqv..kqyqitnWdstg.kvtepqtillvieemyktq
RKTGNNPILVHCSDTVSRSGVFCVLYTSIQQMKIEQQVNIYEILYNMRTCKPGLITTPVQYKMVYLLLMRYVEEFEAYGNF
|| || .|.||||||| ||..|| |.|.. | | ......| ..| ||| . | |||... ... |.. ||.| .|
rkrgntsivvhCsdtvGrsamfcaaattinkckteGviDvfqvlksqriqkpgsvqtveqykfindivleyldsfetysdf
|
|||||||||
subfamily_PTPRA_pd | Subfamily PTPRA | 667-953 | 7.5e-63 | 207.4 | In-house | 27-308 (330) | alignment | ||
Range on Protein: 667-953
Range on HMM: 27-308/330.0
KSNGGKGFKSEFQRLQNFGHLFSTEVANCSENKKRNRFKTILPYDNNLLTLRPIssRGDCSHSYINASYIDGYKKKHQFIATQGPLPQTLVDFWRLIWQE
... | |. ||. | . |.|. |||..||. ||||| . . | .. .| . |||||.|||||.|..|||.|||. .|. ||||.||.
saddnklfreefnalPagpiqatlelaskeenkeknrvvnilPydfsrvilsvk..eGveesdyinasfidGykekdkfiaaqGPkeetvedfwrmiweq
DICCILMMLSITsDGGIVRCQQYWPDAiGVAAfYGPFKIIVEgiNDNKVSEERIIKLSMT--SSSSSDNSHKTIHHYLFKCWPDHGVPATPTSTHSFYEQ
. . |.|. . . .|.||||| |. . || .. || ... . . . |. .. . .. ..... .. . |. ||| |||..| .. ..
ksativmltelk.erkeekcaqywPde.Glvt.yGnirveve..detvlvdytvrkflvqqlpdatrekksrlvrqfhftswPdvGvPfepiGmlkllkk
IKMWLD-LPPPVLIHCSGGIGVTGMLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEaFYTIGKESITPSNLQ
.| . |. .||| |.| || .| . .|. . . ||| .|...| || .|.||.|||.|.. |||| .| | . | |.
vkklnqqsagpivvhcsaGvGrtGtfivldavlervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvlle.yylygdteldvssle
|
|||||||||
subfamily_PTPN12_pd | Subfamily PTPN12 | 669-939 | 7.6e-63 | 207.1 | In-house | 5-277 (290) | alignment | ||
Range on Protein: 669-939
Range on HMM: 5-277/290.0
NGGKGFKSEFQRLQNFG------HLFSTEVANCSENKKRNRFKTILPYDNNLLTLRPISSRGdcSHSYINASYIDGYKKKHQFIATQGPLPQTLVDFWRL
.| . |..|||.|.. . .|||... .||.|.||.| |||||.. ..|. |.. .||||..| | ..|...||.|||||.|| ||||.
egeeefakefqklkklsekykaekvysteagekeenvkknrykDilPydksrvelskieeee..gsdYinanfikgvegkleyiaaqgPLpktlddfWrm
IWQEDICCILMMLSITsDGGIVRCQQYWPDAIGVAAFYGPFKIIVEgiNDNKVSEERIIKL-SMTSSsssdNSHKTIHHYLFKCWPDHGVPATPTSTHSF
||. .. ..|. . . | .|..|||. . . .|.|.. .| ....|... .|. .. . . ..... . .. |||||||....| ..
iweknveivvmaCrev.elgkkkCerYWpeegeeelefgefevtle..eekavdddflirtLkveaq....kesrkvyqfhYtaWPDhgvPssaksllel
YEQIKMWL-DLPPPVLIHCSGGIGVTGMLISIMIG---IEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEAF
|... . |...||| |.| || .|.| . .... . .|| .| ..| || ..||.|||..|. ..| .
ielvrelqesedaPlvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelv
|
|||||||||
0042113 | (Phosphotyrosine protein) phosphatases II | 692-937 | 8.6e-63 | 207.3 | In-house | 3-241 (245) | alignment | ||
Range on Protein: 692-937
Range on HMM: 3-241/245.0
VANCSENKKRNRFKTILPYDNNLLTLRPISSrgDCSHSYINASYIDGYKKKHQFIATQGPLPQTLVDFWRLIWQEDICCILMMLSITSdGGIVRCQQYWP
||. |||..||.. |||||... | |... | ..||||||.|||. ...|||||||||.|. ||||..|...| .|.|. . . | | |.||||
vallpenkdknrysdilpydhtrvklspdgg..dldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeee.lgrvkcaqywp
DaiGVAAFYGPFKIIVEGINDNKVSEERIIKLSMTssssSDNSHKTIHHYLFKCWPDHGVPATPTSTHSFYEQIKMWLD--LPPPVLIHCSGGIGVTGML
. | || |.. . ... .. |....... |. .....||.. ||||||| .. . .|.| .. .| . |||.|||.|.| ||..
l..gesltygdftvtllseehlddytvrtlevtnl....gddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtf
ISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLE
| . . .|| ...||.. .| ..||||....||..||.|....|||
iaaylmleqlekelgvsleeavkelrsqRpgavqtpsqyrflyealle
|
|||||||||
0050432 | (Phosphotyrosine protein) phosphatases II | 955-1235 | 1.4e-61 | 203.9 | In-house | 28-303 (308) | alignment | ||
Range on Protein: 955-1235
Range on HMM: 28-303/308.0
IVKRLGKHDEILNMNRYEAHYKALQVLTVkPNSVLRNFGLSNLPLVRSDLYLPPDEYRVVLnKKTEDFIHASYINGY--QEARSFIVAESPTKLTAANFW
. . | .... |.. ..|. ...|. ... ... | .. |. .|| | ||.| ... |.|.|||..|| | ||.. .|.. | ..||
vldllkllekaldlglleeefeellsvkp.lleysvallpenkdkNrykdilpydhsRVkl.degsdYInAsyvdgyssklprkfIatqgPlpntvedFw
SMIVKNKCSVIVMLCDIVEMEVDTCYQYWPATYD-SERHFDFYRIKHHEMNIDNYYTQTILRVLDTQAGEEQTIILIQLPLSNivsDELSHTERVGILSA
|. .....|||||...||... .|.|||| ... . .... ..... .. ....||.. |.. ... ||. |. .. . | .. .|.
rmvweqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseevlddytvrtleltnlgdgesrtvthfhytnWp...dhgvPpspeilldf
IQEIEKIQrktGNNPILVHCSDTVSRSGVFCVLYTSIQQMKIEQQVNIYEILYNMRTCKPGLITTPVQYKMVYLLLMRYVEEFE
.....| . ...||.||||. |.|.|.|..|.. ..|.. |. |...|... .|...|| ..|| ||. .| .|. |.. ..
lelvrksl...pggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylflyralleylklkl
|
|||||||||
subfamily_PTPN6_pd | Subfamily PTPN6 | 665-936 | 1.6e-61 | 203.0 | In-house | 19-294 (306) | alignment | ||
Range on Protein: 665-936
Range on HMM: 19-294/306.0
LNKSNGGKGFKSEFQRLQN--FGHLFSTEVANCSENKKRNRFKTILPYDNNLLTLRpisSRGDCSHSYINASYIDGY--KKKHQFIATQGPLPQTLVDFW
..| . .||. ||..||. .|.| . .. |||..||.|.|||.|.. ..|. . . . ||||.||.. ......||||| |..|. |||
eeeslekagfeeefeelqqeeakkllsrkegakpenkeknryknilPfDhtrvilk...epsvpgsdyinanyikkevkgsdksyiatqgclettvsdFW
RLIWQEDICCIlMMLSITSDGGIVRCQQYWPDAIGVAAfYGpfKIIVEGINDNKVSEERIIKLSMTSSsSSDNSHKTIHHYLFKCWPDHGVPATPTSTHS
|..|||. | .|. . | .| .||||. . || || |. ..... .. . .||.. ...........| || |||||||. | .
rmvwqensrvi.vmttkevErgkekCarYWPdeeekee.yG..kisvtnvseksladYilRelsvskk.kkkkeerevfqyhfksWPdhgvpkdpgavLd
FYEQIKMWLDLPP-----PVLIHCSGGIGVTGMLISIMIGIEQGLST---GGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLL
| |.... . |...||| ||| || .| | | ... .. .|. .|...|.|| ..|||.||.||....
fledvnrkqeeleeaeagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqteqqykfvykaik
|
|||||||||
subfamily_PTPRG_pd | Subfamily PTPRG | 653-941 | 4.8e-61 | 201.6 | In-house | 1-289 (563) | alignment | ||
Range on Protein: 653-941
Range on HMM: 1-289/563.0
VKLSEFADHIELLnKSNGGKGFKSEFQRLQN--FGHLFSTEVANCSENKKRNRFKTILPYDNNLLTLRPISSRgDCSHSYINASYIDGYKKKHQFIATQG
|...||| |. | ...| .||. ||. ||. . . .| .. |||..|| |..||. .|.|.. . .. ||||.|||||.|...||||||
vpvkefakhvasl.hadgdigfseefealqsetiskdldaehsqkpenkrKnRylnivaydrsRvklsplpgk.kkklDYinAnyidGyqkskafiatqg
PLPQTLVDFWRLIWQEDICCILMMLSITSDgGIVRCQQYWPDaiGVAAFYGPFKIIVEGINDNKVSEERIIKLSMTSSS-SSD-NSHKTIHHYLFKCWPD
||..|. ||||.||.. | |. .. . | |..||| . || ... . . .. .| ... . .. ...|.. .| . |||
plkdtfddFWrmiWeqnvaiivmitnlver.grrkcdvYWPk..desetygalqvtlieeevlalytvrtlviknlklkkkkqcdteklvrqyhytkWPd
HGVPATPTSTHSFYEQIKMWLD-LPPPVLIHCSGGIGVTGMLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEAFYT
|||| .. .| .. . |...||| |.| ||..| . ..| . |.| .. ..|.|| ...||||||.|.| .|||| .
hgvPehslpvLifvkkssaankaeaGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvqteEqYiflhdalleaias
|
|||||||||
subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 666-938 | 5.2e-61 | 201.1 | In-house | 14-277 (287) | alignment | ||
Range on Protein: 666-938
Range on HMM: 14-277/287.0
NKSNGGKGFKSEFQRLQNFGHLF-STEVANCSENKKRNRFKTILPYDNNLLTLRpissrgDCSHSYINASYIDGYKKKHQFIATQGPLPQTLVDFWRLIW
.. .| .||| |. |.. .. . .. |.||..||.. ||..||. . |. .. . ||||..|||||.|..||....|. .|...||.||.
ghakgnegfknqftvleqvtqredevthniasqnkdknRltqilvpdnyrvllk......gehpdyinavfidgykekkafiiaesPmfntarnfWklid
QEDICCILMMLSITsDGGIVRCQQYWPDAIGvaAFYGPFKIIVEGINDNKVSEERIIKLsmTSsSSSDNSHKTIHHYLFKCWPDHG-VPATPTSTHSFYE
.. . |.|. . . | ||||. .|...| . . |. || ... . ........... | . |...| |. |. . |
drnvtaivmlcqek.endeevcyqyWpeeks..vvlGeyniellneevnagyierklev..kn.knkagdkqqvkqyqitnWdstgkvtepqtillviee
QIKMWL-DLPPPVLIHCSGGIGVTGMLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEA
..| ....||| ..| ..|.... ..|.. |..||. .....| |.....|| |||.|. ..||
myktqrkrgntsivvhCsdtvGrsamfcaaattinkckteGviDvfqvlksqriqkpgsvqtveqykfindivley
|
|||||||||
0036941 | (Phosphotyrosine protein) phosphatases II | 968-1234 | 5.6e-61 | 201.8 | In-house | 12-280 (297) | alignment | ||
Range on Protein: 968-1234
Range on HMM: 12-280/297.0
MNRYEAHYKALQVLTVkPNSVLRNFGLSNLPLVRSDLYLPPDEYRVVLNKKTEDFIHASYINGYQEARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLC
..... ... |. | . . | . ||.. |. .|| | ||.|.. |.|.|||..||. | ||... |.. | ..|| |. .....|||||.
lalllkefeellplll.lgslsvallpenleknRykdilpydhtRVklddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqnvtvIvmlt
DIVEMEVDTCYQYWPATYDSERHFDFYRIKHHEMNI--DNYYTQTILRVLDTQAGEEQTIILIQLPLSNivsDELSHTERVGILSAIQEIEKIQRKT-GN
. ||.. .|.|||| . ... .. .... .... ...||.. |.|.||. ||. |. .. . | . .|. |....|..... ..
elvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwp...dhgvpespaslldfielvrkvlkllpsg
NPILVHCSDTVSRSGVFCVLYTSIQQMK---IEQQVNIYEILYNMRTCKPGLITTPVQYKMVYLLLMRYVEEF
.|.|||||. |.|||.|..... .||.. .|..|.|.|.. .|...|| ..|. ||. .| .|. .. .
gpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallellkkk
|
|||||||||
0047943 | (Phosphotyrosine protein) phosphatases II | 964-1231 | 9.4e-60 | 197.7 | In-house | 7-272 (273) | alignment | ||
Range on Protein: 964-1231
Range on HMM: 7-272/273.0
EILNMNRYEAHYKALQVLTVkPNSVLRNFGLSNLPLVRSDLYLPPDEYRVVLNKKTEDFIHASYINGYQEARSFIVAESPTKLTAANFWSMIVKNKCSVI
. |....... ...|. |.. . . |. . |. .|| | ||.|. .. |.|.|||..||. | ||... |.. | ..|| |. .....||
kllgltllleefelllslkp.lltysvallpenkdknrykdilpydhsrvklgdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvweqnvrvi
VMLCDIVEMEVDTCYQYWPATYDS-ERHFDFYRIKHHEMNIDNYYTQTILRVLDTQAGEEQTIILIQLPLSNivsDELSHTERVGILSAIQEIEKIQRKT
|||...||.. .|.|||| . .. . .. ..... .......||.. |.. ... ||. |.. .. . | . .|. |....|.....
VmLtelvelgrekcaqYwpleggelsltygkftvtllseetkddytvrtleltnlgtgesrtvthfhytgwp...dhgvppslesllefielvrkaleal
-GNNPILVHCSDTVSRSGVFCVLYTSIQQMKIEQQVNIYEILYNMRTCKPGLITTPVQYKMVYLLLMRYV
.|.|..||||. |.|.|.|..|.. ..|.. |..|...|... .|...|| ..|| ||...| .|. |.
psngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyealleyl
|
|||||||||
0051299 | (Phosphotyrosine protein) phosphatases II | 966-1231 | 2e-59 | 196.7 | In-house | 20-286 (288) | alignment | ||
Range on Protein: 966-1231
Range on HMM: 20-286/288.0
LNMNRYEAHYKALQVLTVKpNSVLRNFGLSNLPLVRSDLYLPPDEYRVVLNK----KTEDFIHASYINGYQEARSFIVAESPTKLTAANFWSMIVKNKCS
....... ...|. |... ... ||. |. .|| | ||.|. . |.|.||||.||. | ||... |.. | ..|| |. .....
ngltglleefeellsllpd.ltlsaallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyidgynlkrkfIatqgPlpntvedFWrmvweqnvr
VIVMLCDIVEMEVDTCYQYWPAtyDSERHFDFYRIKHHEMNIDNYYTQTILRVLDT--QAGEEQTIILIQLPLSNIVsDELSHTERVGILSAIQEIEKIQ
|||||...||... .|.|||| .. .. .... .. ....||.. |.| .. |...... ... |. | . .|. .... | .
vIvmltklvelgrekcaqYwpl..ggsltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwp.dhgvpdspellldflrlvrkal
RkTGNNPILVHCSDTVSRSGVFCVLYTSIQQMKIEQQVNIYEILYNMRTCKPGLITTPVQYKMVYLLLMRYV
. |..|..||||. |.|.|.|..|.. ..|.. |. |...|.. .|...||...|| ||..|| .|. |.
a.sgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyealleyl
|
|||||||||
subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 689-937 | 8.2e-59 | 193.9 | In-house | 19-266 (274) | alignment | ||
Range on Protein: 689-937
Range on HMM: 19-266/274.0
STEVANCSENKKRNRFKTILPYDNNLLTLRPISSRGDcSHSYINASYIDGYKKKH-QFIATQGPLPQTLVDFWRLIWQEDICCILMMLSITSdGGIVRCQ
..| . . ....||.||||| .| ..|.. ||. . ||||| || ||.... ..|||||||.|. ||||.|.||.. |.|. .. .|.
dqeeldvfgsqtknryktilPnensrvllesessede.dssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklke.aneqkCa
QYWPDAIGV--AAFYGPFKIIVEGINDNKvsEERIIKLSMTSSSS--SdnshktIHHYLFKCWPDHGVPATPTSTHSFYEQIKMW---LDLP-PPVLIHC
.|.|||... . || ..| ||.|.... . .. ||.. .... | ..||.. |||| .| ... .. .... . . ||..||
vyfPdaedyeiserygdveikvekivern..dysvrklvlkylerers......vkhywytdWPdhksPddantlldlvleveesreeenaklapvvvhC
SGGIGVTGMLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLE
| ||| ||. |.| |.. | .. |||. || ..| .| |.||.|||...| .| .
saGiGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralcl
|
|||||||||
subfamily_Ptp69D_pd | Subfamily Ptp69D | 668-939 | 1.6e-58 | 193.3 | In-house | 18-286 (307) | alignment | ||
Range on Protein: 668-939
Range on HMM: 18-286/307.0
SNGGKGFKSEFQRLQNFGHLFSTEVANCSENKKRNRFKTILPYDNNLLTLRPISSRGDcsHSYINASYIDGYKKKHQFIATQGPLPQTLVDFWRLIWQED
. |.. |...|.. ||.|.. ||. .||.. | ..|.. |..| . | .|||||.| |||.|..||| |.|. .|. ||||.|.. .
rdtdfglakeyekLeareidkstkvsekkenalknRyedikafDktRvkLkkingked..sdYinasfikgykekkkfiaaqdPveatigDfWRmiaeqe
ICCILmMLSITSDGGIVRCQQYWPDAigVAAFYGpfKIIVEGINDNKVSE--ERIIKLSMTSSSS-SDNSHKTIHHYLFKCWPDHGVPATPTSTHSFYEQ
. | ||| .. .|..|||. || .|.|. .. .| |. .| ...|.. .| . .. . | .. |.| || .... . ||
vtliv.mlsnlteknrkkcakYWpie..devqyg..dilvklvseekhsdyiiReldvskkkeesgevedsrkvvqyhytgWkDskvPevargllklieq
IK-MWLDLPPPVLIHCSGGIGVTGMLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEAF
.. . |...||| | | .|..... . ..| ||....| ..|||| ..| |||.|.. ||.
vrelyklnrsPivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnllvqsleqYvflyralldys
|
|||||||||
subfamily_PTPN9_pd | Subfamily PTPN9 | 667-937 | 2.9e-58 | 192.3 | In-house | 11-288 (297) | alignment | ||
Range on Protein: 667-937
Range on HMM: 11-288/297.0
KSNGGKGFKSEFQRLQNFGHLFSTEVANCSENKKRNRFKTILPYDNNLLTLRPISsrGDCSHSYINASYIDGYKKKHQFIATQGPLPQTLVDFWRLIWQE
|..| .| . |.. ..| .... | ..||.. .| ||. ..| .. .| ||||...||||.|. ||||||||..| ||||..|..
kekgkrGlskeyaeirnepveGtflasklranleknrytdvlcydetrvvlakvd..edeasdyinanfvdGykqkkafiatqGplkktvsdfWrmvWeq
DICCILMMlSITSDGGIVRCQQYWPDAIGVAAFYGpfKIIVEGINDNKVSEERIIKLSMtsSSSSDNSHKTIHHYLFKCWPDHGVPATPTSTHSFYEQIK
.. |.|. . . | ..|.||||. . .| .| .. |. ..... .. .. .| . . . .. .... |. | |||.||| . .| . |...
evlvivmt.trvvergrlkcgqyWpleeessaefg..dlsvsnveveeeedykvrvlei..knvkteesrkvthfqflsWPdyGvPssaaslldvlekvr
MW------------L--DLPPPVLIHCSGGIGVTGMLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLE
||...||| ||| || .|.. | ... ..| |||. |...|.|| .|||.|||.| . .||
ekqalavkelgdewkghpsgPPivvhcsaGiGrtGtfitldiclsrleevgtvdvvetvkllrtqrafsiqtpeqyefcylavle
|
|||||||||
0046845 | (Phosphotyrosine protein) phosphatases II | 974-1234 | 1.3e-57 | 190.7 | In-house | 5-277 (284) | alignment | ||
Range on Protein: 974-1234
Range on HMM: 5-277/284.0
HYKALQVLTVKPN-SVLRNFGLSNLPLVRSDLYLPPDEYRVVLNK-----KTEDFIHASYINGY-----QEARSFIVAESPTKLTAANFWSMIVKNKCSV
...|. ||||. |. . || . |. .|| | ||.|. .. |.|.|||..|| . ||.. |.. | ..|| |. .....|
efeellsltvklllslsvallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqnvrv
IVMLCDIVEMEVDTCYQYWPATyDSERHFDFYRIKHHEMNIDNYYTQTILRVLDTQAgEEQTIILIQLPLSNIVsDELSHTERVGILSAIQEIEKIQRK-
||||...||... |.|||| . .. ... .... .......||.. |.. ... .......... .. | .. .|. ..........
IVmltelvengrekcaqYwple.gevltygdftvtllseevkddytvrtleltnlgy.tgesrtvthfhytswp.dhgvppspedlleflrlvrellenl
TGNNPILVHCSDTVSRSGVFCVLYTSIQQMKIEQ---QVNIYEILYNMRTCKPGLITTPVQYKMVYLLLMRYVEEF
|..||.||||. |.|.|.|..|.. ..|.. |. |...|... .|...|| ..|. ||..|| .|. |. .
pgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleylklk
|
|||||||||
subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 667-948 | 3.3e-57 | 188.8 | In-house | 19-287 (315) | alignment | ||
Range on Protein: 667-948
Range on HMM: 19-287/315.0
KSNGGKGFKSEFQRLQNfGHLFSTEVANCSENKKRNRFKTILPYDNNLLTLrPISSRgDCSHSYINASYIDGYKKKHQFIATQGPLPQTLVDFWRLIWQE
|.. .||| ... . |.|. .||. .|||..||. |..||. | |. | |.||..||||.||...||.|||..... |||||...|
kastkngfkqdyesipg.gqlhpldvakkienkqknryiniiaydksrvql.pllen.dphsdyvnanfidGynkkrryiaaqgpnvasvkdfwrlvfee
DICCILmMLSITSDGGIVRCQQYWPDAigvAAFYGPFKIIVEginDNKVSEERIIK-LsmtsSSSSDNSHKTIHHYLFKCWPDHGVPATPTSTHSFYEQI
|| |. ||. . .| ....|||| ||.. . ...| .| .. | | ... ... . . .||| |||. .. .. ..
digkiv.mltnlvegekrkaekywpdk...kviyGkitvtrk...seevnteytvrtl....svvfgdnirevvqlhytswpdmgvpkytiplmnlirtv
KMWLDL-PPPVLIHCSGGIGVTGMLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEAFYtIGKESIT
|.. . ....||| |.| || .|.. ..| .|| .....|..|..|.|. |||||.. .|||.| | ||.
kqhhtnsvgaivvhcsaGvGrtGtfitldavldqaeaenaidvynfitgvrqnrikmvqvaeqyqfiydalletfv.cgdtsia
|
|||||||||
subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 663-940 | 5.2e-57 | 188.1 | In-house | 10-278 (315) | alignment | ||
Range on Protein: 663-940
Range on HMM: 10-278/315.0
ELLNKSNGGKGFKSEFQRLQNfGHLFSTEVANCSENKKRNRFKTILPYDNNLLTLRPISSrgDCSHSYINASYIDGYKKKHQFIATQGPLPQTLVDFWRL
..|| | ||. | . . . || ..| |.||.| |||.|.. . | | . . ||||||| .... . .||.||||. .. ||||.
afvnknrhtalfseefhdlpd.PdiyrqrvaretinfkknryknilPldsarvklevidd..sPdsdyinasyiksvdddkayiasqgPlkasvddfwrm
IWQEDICCILMmLSITSDGGIVRCQQYWPDAIGVAAFYGPFKiiVEGINDNKVSEERIIKLSMTSSsssDNShKTIHHYLFKCWPDHGVPATPTSTHSFY
..||.. | | .. ..| ..|.||||| . .. .| .| || .. . .. . || . | ..| .|. . |. |||.||. .| .
vlqekvttivm.vtkkqegdkikcrqywPdrkadsvefGsik..vellsleadtdgvarklvtrks...ees.rtvtqfqftewPdkGvdkqtssllkli
EQIKMWLD-LPPPVLIHCSGGIGVTGMLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEAFY
..| . ..|.||| |.| ||..|||. ..| | |||. .|...|..|. ..||||.| |.. ..|| ..
kevkadngkkefsllvhcsaGvGrtGvvisidevvaqikrtrsvdvfnfvknlrakrpylvqteeeyafiydavledll
|
|||||||||
0040438 | (Phosphotyrosine protein) phosphatases II | 971-1235 | 8e-57 | 188.3 | In-house | 20-280 (317) | alignment | ||
Range on Protein: 971-1235
Range on HMM: 20-280/317.0
YEAHYKALQVLtvKPNSVLRNFGLSNLPLVRSDLYLPPDEYRVVLNKKT----EDFIHASYINGYQEARSFIVAESPTKLTAANFWSMIVKNKCSVIVML
. ... |. | |... . | .. |. .|| | ||.|. . |.|.|||..|... | ||.. .|.. | ..|| |. .....|||||
lleefedllsl..kldtysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPlpntvedFwrmvweqgvtvivmL
CDIVEMEVDTCYQYWPAtyDSERHFDFYRIKHHEMNIDNYYTQTILRVLDTQAGEEQTIILIQLPLSNivsDELSHTERVGILSAIQEIEKIQRkTGNNP
.. .|... .|.|||| ... ... ..... .. ....| . |.| |.. .|. |. .. . | .|. ...... .. ...|
teleelgrekcaqYwpl..getltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWp...dhgvppspdllldfleavreale.dpggp
ILVHCSDTVSRSGVFCVLYTSIQQMKIEQQVNIYEILYNMRTCKPGLITTPVQYKMVYLLLMRYVEEFE
.|||||. |.|.|.|...|. ..|.. |..|...|... .| ..|| ..|| ||. .| .|. |. ..
vlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleylkrkl
|
|||||||||
subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 672-940 | 9.6e-57 | 187.7 | In-house | 34-292 (319) | alignment | ||
Range on Protein: 672-940
Range on HMM: 34-292/319.0
KGFKSEFQRLQNFGHLF-STEVANCSENKKRNRFKTILPYDNNLLTLRPISsrGDCSHSYINASYIDGYKKKHQFIATQGPLPQTLVDFWRLIWQEDICC
. .. ||.|. . | . || .|| .||. ||..|.| . |... | |||||...||..| ..||.||||. || ||||.||. ...
tklevefrracklgvnladqtfanldqnkdknriinilafdknvvklerli..GeefsdyinasfvtGyqrkdkyiaaqGPldntladfWrmiweyncst
ILMMLsitsdggIVRCQQYWPDAIGVAafYGPFKIIVEGINDnkvSEERIIKLSMTSSSSSDNSHKTIHHYLFKCWPDHGVPATPTSTHSFYEQ---IKM
|... .| |||| | . .. ||. |. ... ..| ... | . . . |. . |. |||.||| |. . .. ..
ivllt.......kdkcsqywplkivik..eerfkvkvdsvee...taeyvvrdielsedgkekdirkitqfhflGwpdvGvpdypsdlmrlvkkvrhlts
WLDLPPPVLIHCSGGIGVTGMLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEAFY
. . ....||| |.| ||. | . . ... ||| .|. .| || ...| ||.|.. ||| .
kenhranivvhcsaGvGrtGvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleehl
|
|||||||||
0037934 | (Phosphotyrosine protein) phosphatases II | 692-937 | 2.6e-56 | 186.2 | In-house | 4-240 (243) | alignment | ||
Range on Protein: 692-937
Range on HMM: 4-240/243.0
VANCSENKKRNRFKTILPYDNNLLTLrpissrGDcsHSYINASYIDGYKKkhqFIATQGPLPQTLVD----FWRLIWQEDICCILMMLSITsDGGIVRCQ
.|. ||...||...|||||.. | .. ..||||..|..... .||||||||.|. | |||..|...| .|.|. . . . | . |
iallpenlsknrysdilpydhsrvkl......eg..sdyinanliyvtpr...liatqgPlpetveddlasfwrmlwelgitvivmltelv.Elgrekca
QYWPDAIgvaaFYGPFKIIVEGINDNKVSEERIIKLSMtssSSSDNSHKTIHHYLFKCWPDHGVPATPTSTHSFYEQIKMWLDL---------PPPVLIH
||||. . ||.|.. . ... . | ..|.. . |. .....||.. .||||||| .|.. .| .... ... |||.|
qywpgev....tygdftvtllseehlddytvrtlllen...ldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVH
CSGGIGVTGMLISIMIGIEQGlstgGVDVMAIVNKMRSQRMN-MIQTEEQYQFVHYVLLE
||.|.| ||.|| . . ... |||. .|...|.||.. ..||..||.|....|||
CsaGvgRtGtliaaylmllll....gvdleeavkllreqRpgkavqtpsqyrflyealle
|
|||||||||
subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 657-946 | 4.5e-56 | 185.3 | In-house | 9-294 (325) | alignment | ||
Range on Protein: 657-946
Range on HMM: 9-294/325.0
EFADHIELlNKSNGGKGFKSEFQRLQNFGHLfSTEVANCSENKKRNRFKTILPYDNNLLTLRpiSSRGDCSHSYINASYIDGYKKKHQFIATQGPLPQTL
.. .|.| .|.. || ||. | . . . .|| |||..|||| ....|.. | . . | | ||||||. .|||. |.|.| ||..|.
nlvehvek.kkaqdqdgfahefgllpsddgi.akkvamkpenkaknrfknvvaldksrvvle..tkkddpssdyinasylrddkkkdvflaaqaPltati
VDFWRLI--WQediCCILMMLSITsDGGIVRCQQYWPDAIGVAAFYGPFKIIVEGINDNkvSEERIIKLSMTSSSSsdNSHKTIHHYLFKCWPDHGVPAT
|.|||. |. | ....| . |.| || .|||. .| . .|.... . |.. |. .| . . .... . .. |.| ||.
ndlWrlvldWr...csvvvvlnel.dlgkdrcavywpkemgksktfGglevklrtieei..sdyvhrvldvkqvkk..GetrsvkqfqlqswddmGvqkr
PTSTHSFYEQ-------IKMWLDLPPPVLIHCSGGIGVTGMLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEAFYTiGKES
|.. |. . .. |.|.||| |.| ||..||. ... . ||.. |.|.| .| .|..| .|| ... | ||. . |.
patlisilqlvkavservtantkastpilvhcsaGvGrtGvfislysalakvieesrvdifgfvkklrkdrpsmvetvdqyiliyealveayms.gntd
|
|||||||||
subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 666-939 | 5.1e-56 | 184.8 | In-house | 12-276 (515) | alignment | ||
Range on Protein: 666-939
Range on HMM: 12-276/515.0
NKSNGGKGFKSEFQRLQNfGHLFSTEVANCSENKKRNRFKTILPYDNNLLTLRPISSRgdCSHSYINASYIDGYKKKHQFIATQGPLPQTLVDFWRLIWQ
||.. | ||. | .. ||. | |.||.| |||||.. . | | . |.||||| ... . .||.|||.. .. |||||..|
nknrhttlfseefhdlpg.pniypqtvaqeeinfkknryknilPydsvrvklevindn..PhsdyfnasyipsfdndkayiasqgPnkasvddfWrlvlq
EDICCILMmLSITSDGGIVRCQQYWPDAIGVAAFYGPFKiiVEGINDNKVSEERIIKLSMTssSSSDnsHKTIHHYLFKCWPDHGVPATPTSTHSFYEQI
|.. | | .. ..| ..| .|||| | . .| .| || . . .. . || .. ..| .|. . |. |||.||| .| . ..
envttiam.vtklkegdkikcgkyWPdkpgdsvkfGsik..velvsleactggikrkltvl..kgdd..srtvtqfhfteWPdkGvpkhtssllklikev
KMWL-DLPPPVLIHCSGGIGVTGMLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEAF
| . |..|||| |.| ||..|||. . . | |||. .|...| .|. ..||.||| |.. ..|| .
kadhgqythpliihcsaGvGrtGvvisidsvvahakttrmvdvfnfvtnirqkrpylvqtqeqyafiygavledl
|
|||||||||
subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 673-952 | 6.4e-56 | 184.3 | In-house | 10-278 (283) | alignment | ||
Range on Protein: 673-952
Range on HMM: 10-278/283.0
GFKSEFQRLQNfgHLFSTEVANCSENKKRNRFKTILPYDNNLLTLRPISSrgdcshSYINASYID---GYKKKHQFIATQGPLPQTLVDFWRLIWQEDIC
|. ..|| ....| ..|||. ||.. |.|.|.. . |.. | .||||..| ||.....|..|.|| .| ||||.....|.|.
lfrevlkrlsv..pdldadiasadenkrknrnqeivpadqwrvelksesr......dyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekit
CILMMLSITSDgGIVRCQQYWPDAiGvAAFYGPFKIIVEginDNKVSEERIIKLSMTSSSSSDNSHKTIHHYLFKCWPDHGVPAtPTSTHSFYEQIKMW-
.|.|. . | ..| |||| | . ||.| . .. .. |. |||. . .|| .| . || . | . | | . . .....
aivmltklqed.lrikCsqyWPkr.G.sedyGeftvtlr...kettsnsfiikelllrvnssakstlllahyqvidWleygeqa.iinslvkfnkvislq
LDL-PPPVLIHCSGGIGVTGMLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEAFYtIGKESITPSNL
. |...||| ||| |...|... ... |. |||.|.|. || ||| ..|| .||..|| . || | |. .|
teskkgPivvhCstgiGrtavfiaasasvkdaltesvvdvfavvkimreqrmmavqtldqyklvhelvleqal.cgdtqiaavdl
|
|||||||||
subfamily_PTPN13_pd | Subfamily PTPN13 | 675-940 | 1.5e-55 | 183.4 | In-house | 14-270 (273) | alignment | ||
Range on Protein: 675-940
Range on HMM: 14-270/273.0
KSEFQRLQNFGHLFSTEVANCSENKKRNRFKTILPYDNNLLTLRPISSrgdcshsYINASYIDG--YKKKHQFIATQGPLPQTLVDFWRLIWQEDICCIL
. ||. |... | ..||.. |||..||.. .||||. ..| .. |||||.| |.....||.|||||.| |||...|. . |
aeefkelrelkpldtcevgkkkenkdknryrnvlPydetrvklgdegg.......yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaevia
MMlSITSDGGIVRCQQYWPDAIGVAAFYGPfKIIVEGINDNKVSEERIIKLSMTSSSSSDNshKTIHHYLFKCWPDHGVPATPTSTHSFYEQIKMWLDLP
|. . ..| |.|..|||. . .. || .. .| .. . .| .. | |.. . . | | |||||||..... | ... .
mv.tlekekgkvkchrywPesknkklkvsn.rlevellkvqkldgfvvralavkdsesges..revahlnfvkwPdhgvPssaaellqfvaevrrlqtda
PPVLIHCSGGIGVTGMLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEAFY
|...||| ||| .|.||.| . .. .|| ||.|.| || ..||..|| ||. ..||..
gPivvhcsaGiGrsGtlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykailevlk
|
|||||||||
subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 677-940 | 1.5e-55 | 183.7 | In-house | 3-256 (284) | alignment | ||
Range on Protein: 677-940
Range on HMM: 3-256/284.0
EFQRLQNFGHLFS-TEVANCSENKKRNRFKTILPYDNNLLTLRPISsrGDCSHSYINASYIDGYKKKHQFIATQGPLPQTLVDFWRLIWQEDICCILMML
||.|. . | . . || .|| .||. ||..|.| . |... | |||||.| ||..|...|||||||. || ||||.||. ... |...
efrracklgvngtdqtfanldqnkdknrighilafdknvvklerli..GeefsdyinasfitGyqrkdkyiatqGPldntladfWrmiweyncstivllt
sitsdggIVRCQQYWPDAIGVAafYGPFKIIVEGINDnkvSEERIIKLSMTSSSSSDNSHKTIHHYLFKCWPDHGVPATPTSTHSFYEQ---IKMWLDLP
.| |||| | . .. ||. |. ... ||| ... | . . ..|. . |. |||.||| |. . .. .. . .
.......kdkcsqywplkivik..eerfkvkvdsvee...seeyvvrdielsedgkekdirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhr
PPVLIHCSGGIGVTGMLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEAFY
....||| |.| ||. | . . ... |||. .|...| || ...| ||.|.. ||| .
anivvhcsagvgrtgvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleehl
|
|||||||||
subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 964-1233 | 2.4e-55 | 182.8 | In-house | 17-285 (305) | alignment | ||
Range on Protein: 964-1233
Range on HMM: 17-285/305.0
EILNMNRYEAHYKALQVLtVKPNSVLRNFGLSNLPLVRSDLYLPPDEYRVVLNKKTE--DFIHASYINGYQEARSFIVAESPTKLTAANFWSMIVKNKCS
.. . . .||.||.|. . ... | .. . ... .|..| ... ..... |.| |||..||.. ..||| .| | | |.|| .||. | |
rvysdkgleaqykslyee.eesidvgkkeankaknrlkeitlldddriiltekeslddsdyinasyvdgykrkkkyivaqgPlkntvadfWrliveekvs
VIVMLCDIVEMEVDTCYQYWPATYDSERHFDFYRIKHHEMNIDNYYTQTILRVLDtQAGEEQTIILIQLPLSNIVsDELSHTERVGILSAIQEIEKIQRK
.||||...|| . | |.|||| . ...|. . .. .. . . |.. |.. . ..... ..|. | . |. .. .|| |....| |.|
tivmltklveggkdkCrqYWpesktekkefgefsvelksektasdyieRklkisi.ededkesrtvlqyqltdWP.dhGvpqfatsllslikrvqkdqkk
TGNNPILVHCSDTVSRSGVFCVLYTSIQQMKIEQQVNIYEILYNMRTCKPGLITTPVQYKMVYLLLMRYVEE
. |.|||||..|.|.|||... ....| |..|...|.| ..|. ......| || .. | ...
dkgvpllVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkmvqtldqYvflhdaldelitc
|
|||||||||
0045450 | (Phosphotyrosine protein) phosphatases II | 971-1231 | 3e-55 | 183.5 | In-house | 30-304 (307) | alignment | ||
Range on Protein: 971-1231
Range on HMM: 30-304/307.0
YEAHYKALQVLTVKPNSVLRNFGLSNLPLVRSDLYLPPDEYRVVLNK-----KTEDFIHASYI--------NGYQEARSFIVAESPTKLTAANFWSMIVK
.....| |.| . ... . | .. |. .|| | ||.|. .. |.|.|||. .|| | ||.. .|.. | ..|| |. .
lkefekllsvtvfllgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydlkrkfIatqgPlpetvedFwrmlwe
NKCSVIVMLCDIVEMEVDTCYQYWPATyDSERHFDFYRIKHHEMNIDNYYTQTILRVLDT-QAGEEQTIILIQL---PLSNIVSdelshtERVGILSAIQ
....|||||.. ||.. |.|||| . ..| .. .... .......|| . |.| |. . ||. |.. .. | .. . .|. |.
qgvtvivmltelvelgrekcaqywPde.geeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpdhgvpp......sfeelldfie
EIEKIQRKT-GNNPILVHCSDTVSRSGVFCVLYTSIQQMKIEQQ---VNIYEILYNMRTCKPGLITTPVQYKMVYLLLMRYV
|..|..... ...|.|||||. |.|.|.|...|. ..|.. |. |...|.. .| ..|| ...| ||. .| .|. ..
evrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeallell
|
|||||||||
subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 691-942 | 5e-55 | 181.4 | In-house | 2-245 (250) | alignment | ||
Range on Protein: 691-942
Range on HMM: 2-245/250.0
EVANCSENKKRNRFKTILPYDNNLLTLRPISsrGDCSHSYINASYIDGYKKKHQFIATQGPLPQTLVDFWRLIWQEDICCILMMLSITSDGGIvrCQQYW
.||. .||..||. |...|. . | . . || |||||...||.... ||||||||..|..||||....|.. |.|. ... . ..|||
svakkpqnkeknryadiialdssrvvLekek..gdkesdyinasflhgyderkafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt..yhqyw
PdaIGVAAFYGpfKIIVEGINDNKVSEERIIKLSMTSSSssDNSHKTIHHYLFKCWPDHGVPATPTSTHSFYEQIKMWLDL--PPPVLIHCSGGIGVTGM
| . .| || .. |. .... .. . || ... . ...... .. | ||| |||.. |. . .... . ||...|| |.| .|
P..vekaekyG..dvtvsllskeefadytkrklklskak..kaderivrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGa
LISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEAFYTI
| | .|. |||. .....| .|.......||| ||. ..|.| ..
fiaidavlerlkkekvvdvfkvikvlrkdrphavesleqyvfvyeiilkaldsv
|
|||||||||
0043336 | (Phosphotyrosine protein) phosphatases II | 979-1231 | 3.2e-54 | 179.6 | In-house | 28-277 (278) | alignment | ||
Range on Protein: 979-1231
Range on HMM: 28-277/278.0
QVLTVKPNSVLRNFGLSNLPLVRSDLYLPPDEYRVVLNKKT----EDFIHASYINGYQEARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEV
..|..|... . | .. |. .|| | ||.|. . |.|.|||..||. | ||.. |.. | ..|| |. ......||||.. ||...
ellsfkldtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpetvedFwrmvwelgvttivmLtelvelgr
DTCYQYWPatyDSERHFDFYRIKHHEMNIDNYYTQTILRVLDTQAGEEQTIILIQLplSNIVSDELSHtERVGILSAIQEIEKIQRkTGNNPILVHCSDT
.|.|||| .. .. .... ... ...||.. |.| ... ||..|. .. .. ... . .|. .... .... . |.|.|||||.
vkcaqYwp...ggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhy..lgwpdhgvpe.slsllldflkavreale.dsngpvlVHCsaG
VSRSGVFCVLYTSIQQMKIEQQVNIYEILYNMRTCKPGLITTPVQYKMVYLLLMRYV
|.|.|.|..||. ..|.. |. |...|.. .|...|| ..|| ||...| .|. |.
vgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyealleyl
|
|||||||||
0039614 | (Phosphotyrosine protein) phosphatases II | 959-1232 | 1e-53 | 178.1 | In-house | 22-290 (297) | alignment | ||
Range on Protein: 959-1232
Range on HMM: 22-290/297.0
LGKHDEILNMNRYEAHYKALQVLTVkpNsVLRNFGLSNLPLVRSDLYLPPDEYRVVLNKKTE-----DFIHASYINGYQE-ARSFIVAESPTKLTAANFW
| ... ........... |. |.. . | .. |. .|| | ||.|. . . |.|.|||..|| | ||.. |.. | ..||
llllekansktllllefeellslkp..d.ysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIatqgPlpetvedFw
SMIVKNKCSVIVMLCDIVEMEVdTCYQYWPATYDserHFDFYRIKHHEMNIDNYYTQTILRVLDtqagEEQTIILIQLPLSNIVsDELSHTERVGILSAI
|. .....|||||.. ||... .|.|||| . . .. .... . ...||.. |.| . .... .. .. .. | .|...
rmvweqgvtvivmLtklvelgr.kcaqywpeegg...tygdftvtllkvehldgytvrtlevtn....ngesrtvthfqytgwp.dhgvppslelllefl
QEIEKIQRKT-GNNPILVHCSDTVSRSGVFCVLYTSIQQMKIEQQVNIYEILYNMRTCKPGLITTPVQYKMVYLLLMRYVE
.......... ...|.|||||. |.|.|.|...|. ..|.. |..|...|.. .| ..|| ..|| ||. .| .|. ..
elvrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydallellk
|
|||||||||
subfamily_PTPN3_pd | Subfamily PTPN3 | 678-939 | 3.4e-53 | 175.4 | In-house | 21-275 (280) | alignment | ||
Range on Protein: 678-939
Range on HMM: 21-275/280.0
FQRLQNFGHLFSTEVANCSENKKRNRFKTILPYDNNLLTLRpissrgDCSHSYINASYI----DGYKKKHQFIATQGPLPQTLVDFWRLIWQEDICcILM
|..| ....|. .|| ..||.. |||||. ..|. . . ||||.|. .. . ..|||||||..| |||...|.... ...
feqlyrkkpglaisaarkpenlsknryrdilpydatrvklk......esetdyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqkss.liv
MLSITSDGGIVRCQQYWPDAIGVAaFYGPFKIIVEGINDNKvseeRIIKLSMTSSSSSDNSHKTIHHYLFKCWPDHGVPATPTSTHSFYEQIKMWL-DLP
|| . . | |.| ||||. || |.. .| . .| .. .. . .. . ...|.. . ||||||| ... .| |...
mlttlverGrvkChqyWPetedel.eygefsvkcekedetk....syvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklrsgke
PPVLIHCSGGIGVTGMLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEAF
||..|||.||| ||.|| . . . .. | ...|| .|| ||....||..||.|| .|...
ePvvvhCsaGigrtGvlilletalalieaaepvypldivrtmrdqramlvqtasqykfvCeailkvy
|
|||||||||
subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 671-936 | 1.2e-52 | 173.5 | In-house | 14-290 (301) | alignment | ||
Range on Protein: 671-936
Range on HMM: 14-290/301.0
GKGFKSEFQRLQNfGHLFSTEVANCSENKKRNRFKTILPYDNNLLTLRPISSRGDCSHSYINASYIDGYKKKHQFIATQGPLPQTLVDFWRLIWQEDICC
..|......|.. |. |..| .|||. |||| | .||.| ..|.| .. |...||||||||||..|..|||.|||. .||||||||||||
snkfeeqykelke.gedksctvglseenkalnrfknitvyddnriilkpkpnldlcqreyinasyidgysekkkfiaaqgpmkktlvdfWrliwqekpvs
ILMMLSiTSDGGIVRCQQYWPDAIGVAAFYGPFKIIVEGIN--D-----------NKVSEERIIKLSMTssSSSDNSHKTIHHYLFKCWPDHGV-PATPT
|.|. . .| .|.||||.. .|||.. . . ...|.. |. .. .||.| ... . ||..|| . |
ivmvtn.lkegtkskceqywpnseaeseefgpftvtlvneqvyPdfvirqlnvkiqdgsnngyierkfk..vksdksswdvlqlqvtdWpqdGvvreprt
STHSFYEQIKMWLD-LPPPVLIHCSGGIGVTGMLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLL
.. ..|. ||..||| ... .|. .|. ||.|| . | |||. ... .| ... ...| ||| ... |.
vLqviddvihrqqkigggpvvVHCSdtVsrsGvYcsvsiglEQckaegVVdvfqvtkavrrskpgaVtTLeqytsiydvid
|
|||||||||
DSPc_SM00195 | 998-1231 | 4.2e-52 | 172.5 | In-house | 28-262 (263) | alignment | |||
Range on Protein: 998-1231
Range on HMM: 28-262/263.0
PLVRSDLYLPPDEYRVVLNKK----TEDFIHASYINGYQEARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPATYDSERHFDF
|. .|| |. || |.|. ..|.|.|.||.|... ...|.. |.. | . || |....|...||||.. .| . .|..||| . ... |.
sknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengkekcdrywpeesggketfgk
YRIKHHEMNIDN-YYTQTILRVLDTQAGEEQTIILIQLPLSNIVsdELShTERVGILSAIQEIEKIQRKTgNNPILVHCSDTVSRSGVFCVLYTSIQQMK
...| | .... .... |.. .. |.... .| . .. . .|. .....| .... ..||.||||. |.|.|.|... . .....
isvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdh..gvp.dstksvlellravkksksts.sgpivVhCsaGvgRtgtfvtidiilskle
IEQQVNIYEILYNMRTCKPGLITTPVQYKMVYLLLMRYV
|..|.| ||. ..|. .||...| ||...| ...|.
eekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi
|
|||||||||
PTPc_SM00194 | 998-1231 | 4.2e-52 | 172.5 | In-house | 28-262 (263) | alignment | |||
Range on Protein: 998-1231
Range on HMM: 28-262/263.0
PLVRSDLYLPPDEYRVVLNKK----TEDFIHASYINGYQEARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPATYDSERHFDF
|. .|| |. || |.|. ..|.|.|.||.|... ...|.. |.. | . || |....|...||||.. .| . .|..||| . ... |.
sknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengkekcdrywpeesggketfgk
YRIKHHEMNIDN-YYTQTILRVLDTQAGEEQTIILIQLPLSNIVsdELShTERVGILSAIQEIEKIQRKTgNNPILVHCSDTVSRSGVFCVLYTSIQQMK
...| | .... .... |.. .. |.... .| . .. . .|. .....| .... ..||.||||. |.|.|.|... . .....
isvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdh..gvp.dstksvlellravkksksts.sgpivVhCsaGvgRtgtfvtidiilskle
IEQQVNIYEILYNMRTCKPGLITTPVQYKMVYLLLMRYV
|..|.| ||. ..|. .||...| ||...| ...|.
eekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 1000-1228 | 4.7e-52 | 172.1 | Pfam-A | 5-234 (235) | alignment | ||
Range on Protein: 1000-1228
Range on HMM: 5-234/235.0
VRSDLYLPPDEYRVVL--NKKTEDFIHASYINGYQEARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPATYDSERHFDFYRIK
|. .|| |. || | .....|.|.|.|..||.| ..||... |.| | . || |....|..|||||.. .|.. .| |||| . . . ... ....
nRykdilpydktrvklkgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesltygdikve
HHeMNIDNYYTQTILRVLDTQ---AGEEQTIIlIQLPLSNIVsDELSHTERVGILSAIQEIEKIQrKTGNNPILVHCSDTVSRSGVFCVLYTSIQQMKIE
... . ....||.|. . . .|. .. || . | |. .. ..|. |...|| . .. ..|..||||. |.|.|.|..| . ..|.. |
lk.ekekedekeytlrklelkkkkeesekrev.kqlhytnWp.dhgvpespkslldlirkveksk.eaksgpvvVhCsaGvgRtgtfvaldilleqleae
QQVNIYEILYNMRTCKPGLITTPVQYKMVYLLLM
..|....|. ..|...||.... ||...| ...
eevdvlqivkelRkqRpgmvqsleqYiflykail
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 1000-1228 | 4.7e-52 | 172.1 | In-house | 5-234 (235) | alignment | ||
Range on Protein: 1000-1228
Range on HMM: 5-234/235.0
VRSDLYLPPDEYRVVL--NKKTEDFIHASYINGYQEARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPATYDSERHFDFYRIK
|. .|| |. || | .....|.|.|.|..||.| ..||... |.| | . || |....|..|||||.. .|.. .| |||| . . . ... ....
nRykdilpydktrvklkgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesltygdikve
HHeMNIDNYYTQTILRVLDTQ---AGEEQTIIlIQLPLSNIVsDELSHTERVGILSAIQEIEKIQrKTGNNPILVHCSDTVSRSGVFCVLYTSIQQMKIE
... . ....||.|. . . .|. .. || . | |. .. ..|. |...|| . .. ..|..||||. |.|.|.|..| . ..|.. |
lk.ekekedekeytlrklelkkkkeesekrev.kqlhytnWp.dhgvpespkslldlirkveksk.eaksgpvvVhCsaGvgRtgtfvaldilleqleae
QQVNIYEILYNMRTCKPGLITTPVQYKMVYLLLM
..|....|. ..|...||.... ||...| ...
eevdvlqivkelRkqRpgmvqsleqYiflykail
|
|||||||||
0045098 | (Phosphotyrosine protein) phosphatases II | 980-1233 | 6.1e-52 | 172.1 | In-house | 17-274 (278) | alignment | ||
Range on Protein: 980-1233
Range on HMM: 17-274/278.0
VLTVKPNSVLRNFGLSNLPLVRSDLYLPPDEYRVVlnkkteDFIHASYINGYqeARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQ
.|. |.... . |.||.. | .|| | ||. |.|.||||.|| . ||.. |.. |.|.|| |. .....|||||.. ||... |.|
lllgipseitpalylgnldknRykdilpydhsrVk......dYINAsyidgy..pkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaq
YWPAtyDSERHFDFYRIKHHEMNIDNYYTQTILRVLDT----QAGEEQTIILIQL-PLSniVSDELSHTERVGILSAIQEIEKIQR------------KT
||| .. .. .... .. . ..|| . |.| .. . .|. .. ... | . |.. .|.....|.. ..
ywpe..ggsltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwp..dhgvpslpilksflellefirealkllaslllsslllld
GNNPILVHCSDTVSRSGVFCVLYTSIQQMkiEQQVNIYEILYNMRTCKPG-LITTPVQYKMVYLLLMRYVEE
...|.||||| |.|.|.....|. .... |..|...|.. .|...|| .... ||. .| .|.....
sggpvlVHCsaGvgRtGtlvaaylmlell..eggvdlleavkelrsqRpglavqnleqyrflyefllelllr
|
|||||||||
0040439 | (Phosphotyrosine protein) phosphatases II | 995-1231 | 7.3e-52 | 171.8 | In-house | 10-246 (249) | alignment | ||
Range on Protein: 995-1231
Range on HMM: 10-246/249.0
SNLPLVRSDLYLPPDEYRVVLNK----KTEDFIHASYINGYQEARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPAtyDSERH
|... |. .||.| ||.|. |.|.||||.||. | ||.. |.. | ..|| |. .....|||||.. ||.. .|.|||| ...
enkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywpl..ggsle
FDFYRIKHHEMNIDNYYTQTILRVLDTqaGEEQTIILIQLPLSNIVsDELSHTERVGILSAIQEIEKIQRKT-GNNPILVHCSDTVSRSGVFCVLYTSIQ
.. .... .... ..||.. |.. .. .. ... ... .. | .|. |....|..... ..|.|||||. |.|.|.|...|. ..
ygdftvtllsvevkddytvrtleltnl..ydgesrtvlhiqytdwp.dhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylmle
QMKIEQQVNIYEILYNMRTCKPGLITTPVQYKMVYLLLMRYV
|.. |..|...|.. .|...|| ...| ||. .| .|....
qlekelgvdleeavkllrsqRpgavqnpeqyrflyeallell
|
|||||||||
subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 653-941 | 8.2e-52 | 171.2 | In-house | 10-286 (297) | alignment | ||
Range on Protein: 653-941
Range on HMM: 10-286/297.0
VKLSEFADhieLLNKSNGGKGFKSEFQRLqNFGHLFSTEVANCSENKKRNRFKTILPYDNNLLTLRPISSrgDCSHSYINASYIDGYKKkhQFIATQGPL
. ||.|| |..|. . |. ||. | .... ||. | ...|.| ||||| . .|. . . | . |.|||.. |.|. ..|.|| |
iplsdfat...lvqknrhtdvfseeflcl.peaniqpqtvaekkvnfeksRYkniLPydssRvkLaivnd..dpdsDyvnasfvkgnkh..rlittqmPm
PQTLVDFWRLIWQEDICCILMMLSiTSDGGIvRCQQYWPDAiGVAAfYGPFKIIVEGINDNKVSEERIIKLSMTSSsssdNSHKTIHHYLFKCWPDHGVP
..|. |||.....|.. |.|. ... .|..||.| ||.. .| .... ... . .| .... .. ... .. | | |||. |.
katvadfWamvldeqvstivmlnd.dnerdk.kcaryWsdk.gvtt.fGdvsvvllsvsereGfikrelevtkgka....karrvvkqyqfveWPdkave
A--TPTSTHSFYEQI-KMWLDLPP-PVLIHCSGGIGVTGMLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEAFYT
. .| . ... | . . |.|.||. |.| ||.|..| . . . ||.. .|.|.| .|....||.|||.||. ..|||...
rkdsassllklisevrkdfsqnaegPllvhclaGvGrtgvlltidsvvaeakrekevdifglvkklrqerpylvqtkeqykfvyvavlealls
|
|||||||||
0042113 | (Phosphotyrosine protein) phosphatases II | 995-1231 | 1.5e-51 | 170.5 | In-house | 8-243 (245) | alignment | ||
Range on Protein: 995-1231
Range on HMM: 8-243/245.0
SNLPLVRSDLYLPPDEYRVVLNKKT----EDFIHASYINGYQEARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPAtyDSERH
| .. |. .|| | ||.|. |.|.|||..||. . ||.. |.. | ..|| |. ......||||.. .|.. .|.|||| ...
enkdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywpl..geslt
FDFYRIKHHEMNIDNYYTQTILRVLDTQAGEEQTIILIQLPLSNivsdELSHTE-RVGILSAIQEIEKIQRKTGNNPILVHCSDTVSRSGVFCVLYTSIQ
.. .... .......||...|.| ... .|....| .. . . .. .|.......|......|.|.|||||. |.|.|.|...|. ..
ygdftvtllseehlddytvrtlevtnlgddesrevihyhylpwp....dhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmle
QMKIEQQVNIYEILYNMRTCKPGLITTPVQYKMVYLLLMRYV
|.. |. |...|... .| ..|| ..|| ||. .| .|. ..
qlekelgvsleeavkelrsqRpgavqtpsqyrflyeallell
|
|||||||||
subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 945-1237 | 1.9e-51 | 170.1 | In-house | 3-296 (298) | alignment | ||
Range on Protein: 945-1237
Range on HMM: 3-296/298.0
ESITPSNLQLIVKRLGKHDEILNMNRYEAHYKALQVLTV----KPNSVLRNfgLSNLPLVRSDLYLPPDEYRVVLNK----KTEDFIHASYINGYQEARS
. |. ..|. ...| . .. .. .|.. .. |. . . .| |. .| | ... | ||||.| . |.| ||....|.. .
teieaedlkaalqklaavkkkkkltgyalefqrlnsvsseieeeekevark..penkkkNRyadiialdssRvvLekedadeesdYiNAsflhaykgrna
FIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPATydSERHFDFYRIKHHEMNIDNYYTQTILRVLDTQAGEEQTIILIQlpLSNiV
||... | . | ..|| |..... ..|||| ...|.. .. .||| . ..... ... .. . .... | | ... .|... .. ..
fiatqaPltetvedFWrmvteedigtiVmltnleeldktkyhkywPde..gketygeitvsllskeefadlivrklkvskkkeekerevrqlh..fts.W
SDELSHTERVGILSAIQEIEKIQRKTGNNPILVHCSDTVSRSGVFCVLYTSIQQMKIEQQVNIYEILYNMRTCKPGLITTPVQYKMVYLLLMRYVEEFEA
.|. .. .| ...... |...||.|..|.||. | ||| |..... ....|.|| | ..... .|. .||...| ||. .| . ..... |.
pdkgvpenatsvldllrkvrasqqqagnkpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavlealdsfnd
Y
.
e
|
|||||||||
subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 689-936 | 2.3e-51 | 169.4 | In-house | 11-261 (270) | alignment | ||
Range on Protein: 689-936
Range on HMM: 11-261/270.0
STEVANCSENKKRNRFKTILPYDNNLLTLRPISSrgDCSHSYINASYIDGYKKK-HQFIATQGPLPQTLVDFWRLIWQEDICCILMMLSITsDGGIVRCQ
.... . .|| ||.. ||| . .| .... | |||| |. |.... ...||..|||| || .|||.||.| .|.|. .. . | .|.
esdlpeaargkklnRyadiLPsPatRvrleelee..dsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgle.EkgrkkCe
QYWPDAIGVAAFYGPFKIIVEGINDNKVSEERIIKLSMTsssSSDNSHKTIhHYLFKCWPDHGVPATPTSTHSFYEQIKMWLDL---------PPPVLIH
.||| . . || | ....| . .. .| .. .. .... . |. .. ||||||| .. |. | . .|| .. |.|.|
rYWpaepkekvkledgkikvlalseekeegyiltrlrle...ekgeerrlv.HfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvH
CSGGIGVTGMLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLL
|| |.| ||.|| . |... .|. |||.||....| .||...|. |||.|.. ...
csaGvgRtGtlialDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyeflykavv
|
|||||||||
subfamily_PTPN14_pd | Subfamily PTPN14 | 676-937 | 1.4e-48 | 160.4 | In-house | 27-294 (300) | alignment | ||
Range on Protein: 676-937
Range on HMM: 27-294/300.0
SEFQRLQNFGHLFSTEVANCSENKKRNRFKTILPYDNNLLTLRPISSRgdcSHSYINASYIDGY--KKKHQFIATQGPLPQTLVDFWRLIWQEDICCILM
|..|... . ...|. ||...|||| .|||..| . | | |. ||||| | |....|..||||..|. |||...|.... |.|
teyeripkkredallstaklpenaeknrfkdvlPyednrvelsptken...stgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivm
MLSiTSDGGIVRCQQYWPDA--IGVAAFYGPFKIIVEGINDNKVSEERIIKLSMTSSSssdnSHKTIHHYLFKCWPDHGVPATPTSTHSFYEQIKMW---
. . . ..| .. .|.|. . .| ||.. . .| . . .|| |. ..|..| .. ||||||| ... |. |...
lte.eeedgkeksfkyfPkleskkktvefgkfkvttkfsedsdsvittglklkhlpsk....eertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrk
-------LDLPPPVLIHCSGGIGVTGMLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLE
. ||||.||| |.| ||.|| . |. .|. .....| ||| ..|| ||.||. ||..
tnseveskeskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLreqrmllvqtlaqYkfvYkvlik
|
|||||||||
subfamily_PTPN23_pd | Subfamily PTPN23 | 669-938 | 8.2e-48 | 157.7 | In-house | 12-279 (288) | alignment | ||
Range on Protein: 669-938
Range on HMM: 12-279/288.0
NGGKGFKSEFQRLQNFGH--LFSTEVANCSENKKRNRFKTILPYDNNLLTLRpissrgDCSHSYINASYIDGYKK-KHQFIATQGPLPQTLVDFWRLIWQ
.| ... .|. |.. . .. .| . ..||.. |||||.| .|| . |||||.. . .|||||.||..|| |||.....
dgktaldkkfkeleqkqdkearkrsiaiaklyseknrsrdilPyDhnRvklr......gskDDYinAsfvkdlspgcPdfiatqaPlqstlnDFWlmvye
EDICCILMMLSiTSDGGIVRCQQYWPDAIGVAAFYGPFKIIVEGINDNKVSEERIIKLSMTSSSssdnSHKTIHHYLFKCWPDHGVPATPTSTHSFYEQI
. | |.|| .. | ....||| . | . .|.... .. .. . ||..||.. ... |.. | .. ||..||||.| . | ...
qkssviVmlls.keelgkpkvdrYwPedkgetvkfgdlsvtlksvretethvervlkletldad....avksvshlqltsWpelGvPasPetllqfldev
KMWL-----DLPPPVLIHCSGGIGVTGMLISIMIGIEQGL-STGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEA
. . . |...||| |.| ||.. .. ... | .|.. .|...| || .|.|..||..|. . |||
esayeavqrksktPlvvhCsaGvgRtgvfalvyaavrelekgnglldiiqvvsrlreqRrfmvqekeqlkfsyeavlea
|
|||||||||
0041856 | (Phosphotyrosine protein) phosphatases II | 698-940 | 6.3e-47 | 154.8 | In-house | 1-172 (182) | alignment | ||
Range on Protein: 698-940
Range on HMM: 1-172/182.0
NKKRNRFKTILPYDNNLltlrpissrgdcSHSYINASYIDGYKKKHQFIATQGPLPQTLVDFWRLIWQEDICCILMMLsitsdggivrCQQYWPdaigva
|...||.. |||||... .||||....|. . .||||||||..|. ||.|......| .|... . .|||
nldknrysdilpydhsr............dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt..........eelywp......
afygpfkiivegindnkvseeriiklsmtsssssDNSHKTIHHYLFKCWPDHGVPAtptsTHSFYEQIKMWLDLPPPVLIHCSGGIGVTGMLISIMIGIE
.. ......||. ||||||| ...... |...|. . |||.|||.|.| ||.|. . . ..
..................................ellerlgiqylylpwpDhgvpd....ldelldfieevleeggpvlVHCsaGvgRtgtlvaaylmkk
QglstgGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEAFY
. ||.. .|. .||.|..|..|..||.|....||| ..
l.....gvsleeavklvrsrRpgmvitpnqyfflqlallelll
|
|||||||||
subfamily_PTPN1_pd | Subfamily PTPN1 | 674-947 | 1.2e-46 | 153.8 | In-house | 8-279 (290) | alignment | ||
Range on Protein: 674-947
Range on HMM: 8-279/290.0
FKSEFQRLQNFGHLFSTEVANCSENKKRNRFKTILPYDNNLLTLRPISSrgdcshSYINASYIDGYKKKHQFIATQGPLPQTLVDFWRLIWQEDICCILM
.|. .. ... . |.|..|. ||...||.. . ||| ..|. . ||||| .. . |...| ||||||.| ||...|... ...|
ykeiyldirkeasdfptreaklpenrnlnryrdvspydhsrikleradn......dyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskavvm
MLSITsDGGIVRCQQYWPDAIG-VAAFYGPFKIIVEGINDNKVSEERIIKLSMTSSSSSDnsHKTIHHYLFKCWPDHGVPATPTSTHSFYEQIKMWLDLP
. . . . ..|.|||| . . |. |. |. .. |. .. .| .. .. . ..| |. . ||| ||| .|.. .| ... |
lnkvv.ekeqikcaqywPqgeeekellledtklkvkliseerksyytvrllelenlktqe..treilhfhyttwpdfgvpespaaflkflfkvresGsls
---PPVLIHCSGGIGVTGMLI---SIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEAFYTIGKESI
|..|||| ||| .| .. .... ||. . .||. . ..|..|. .||| .| .| . .|| .| ..|
sdvGpavihcsaGiGrsGtfclvdtclvliekkddlssvdikkvllelrkyrlGliqtadqlrfsylaileGakvikgdss
|
|||||||||
subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 958-1239 | 3.1e-46 | 152.5 | In-house | 4-301 (301) | alignment | ||
Range on Protein: 958-1239
Range on HMM: 4-301/301.0
RLGKHDEILNMNRYEAHYKALQVLTVKPNSVLRNFGLSNLPLVRSDLYLppDEYRVVLNKK------TEDFIHASYINGYQEARSFIVAESPTKLTAANF
||.| . . |..|..||.|. . |...| . ..| .. .. |. |..|..| ....| ||||.||.|.. ||.|..| | | ..|
dlgthvaakhsnkfeeqykelkegedksctvglseenkalnrfknitvy..ddnriilkpkpnldlcqreyinasyidgysekkkfiaaqgpmkktlvdf
WSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPATYDSERHFDFYRIKHHEMN-------------IDNYYT-QTILRVLDTQAGEeQTIILIQLPLSNIVS
| .|...| . |||... | . |.|||| . .. .| . .. .. . | . . | | ..... .. ..|| . .
WrliwqekpvsivmvtnlkegtkskceqywpnseaeseefgpftvtlvneqvyPdfvirqlnvkiqdgsnngyierkfkvksdk.sswdvlqlqvtdWpq
DELSHTERVgILSAIQEIEKIQRKTGNNPILVHCSDTVSRSGVFCVLYTSIQQMKIEQQVNIYEILYNMRTCKPGLITTPVQYKMVYLLLMRYVEEFEAY
| . . | .| .|... . |.| | |..||||||||||||.| . .. | | | |..... .| ||| .|| || ..| . .|.. ..|
dGvvreprt.vLqviddvihrqqkigggpvvVHCSdtVsrsGvYcsvsiglEQckaegVVdvfqvtkavrrskpgaVtTLeqytsiydvidmylqlnsty
GN
.|
an
|
|||||||||
subfamily_PTPRD_pd | Subfamily PTPRD | 1007-1236 | 1.7e-45 | 150.8 | In-house | 59-286 (564) | alignment | ||
Range on Protein: 1007-1236
Range on HMM: 59-286/564.0
PPDEYRVVL----NKKTEDFIHASYINGYQEARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPATyDsERHFDFYRIKHHEMN
. |. |||| ... |.| ||.|.||.. ...| . |.. | ..|| |. ...|.|||| ..|.. . | .|||.. . . ... . .. .| .
aYdhsRVvLskvegdegsDYINAsfidgyrkrkayIAtqgPlaetiedFWRmvweqnsstiVmltkleEkgkvkchkYWPek.g.tetygeltVtleeee
IDNYYTQTILRVldTQAGEEQTIILIQLPLSNIvSDELSHTERVGILSAIQEIEKIQrKTGNNPILVHCSDTVSRSGVFCVLYTSIQQMKIEQQVNIYEI
..|. . ... ... .... | . |. .. ..|. |....... .... ||.|||| | |.|.|.|. ....| |..|.||..
eladyeirtfkl..kkkkssesreVrqFhFtsW.PdhgvpesatslLdlirkvraln.epdagPivVhCSaGVGRTGtfividamlerikeektvDiyqy
LYNMRTCKPGLITTPVQYKMVYLLLMRYVEEFEA
. ..|. .. .. |. || .. .. ... ..
vkalrkqRnamVqteeQYiFiheailealacgnt
|
|||||||||
subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 1004-1238 | 3.3e-44 | 146.0 | In-house | 17-249 (250) | alignment | ||
Range on Protein: 1004-1238
Range on HMM: 17-249/250.0
LYLPPDEYRVVLNKKT----EDFIHASYINGYQEARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDtCYQYWPAtyDSERHFDFYRIKHH
... |. ||||.|. |.| ||...||.| ..||.. .| . | .|| |....| ..|||| ...|.| . ||||. . ... ... .
diialdssrvvLekekgdkesdyinasflhgyderkafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqywPv..ekaekyGdvtvsll
EMNIDNYYTQTILRVldTQAGEEQTIILIQLPLSNIvSDELSHTERVGILSAIQEIEKIQRKTGNNPILVHCSDTVSRSGVFCVLYTSIQQMKIEQQVNI
. .. ||.. | . ..| ... |. || . | . .| ...... |...||.|..|.|| |.||| |..... ....|.|..|..
skeefadytkrklkl..skakkaderivrqlhfvvW.PdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidavlerlkkekvvdv
YEILYNMRTCKPGLITTPVQYKMVYLLLMRYVEEFEAYG
.... .|. .|. ... || .|| ....... .| |
fkvikvlrkdrphavesleqyvfvyeiilkaldsvedya
|
|||||||||
subfamily_CG7180_pd | Subfamily CG7180 | 694-939 | 5.3e-44 | 145.0 | In-house | 38-290 (296) | alignment | ||
Range on Protein: 694-939
Range on HMM: 38-290/296.0
NCSENKKRNRFKTILPYDNNLLTLRPISsrGDCSHSYINASYIDGYKKKHQFIATQGPLPQTLVDFWRLIWQEDICCILMmLSITSDGGIvRCQQYWPDA
.||...|| ...|||.| |. . |. . ||||.|.|.. ||...| |..| .|. .||||...|.| .. . |. | | ...|||
lrkenreknrdvkvvPyDynRvvLekld..GeeksdYinavyvdsflkkkeyivteapkketvdefWrlvydeeisavvv.Ltktfdfak.mypsywpnk
IgvAAFYGPFKiiVEGINDNKVS--EERIIKLSMT------SSSSSDNSHKTIHHYLFKCWPD-HGVPATPTSTHSFYEQIKMWLDLP------PPVLIH
. ||.. || .. .. . . | .|| . . ...... ...|. . || .. . .....| . ||...
s..keqygeif..veiveekqyanlkirtfkltkkivalteqekqvkaetRivklfqlteWeledkvPlstnalielrrrvrlwrekvdedpeegPvvvv
CSGGIGVTGMLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEAF
.| | . .|. ..| . .|. .. ||| | ..| .| ..... |.|... |||||.
ssdGasRsGvylaidanlelvekeeevdvFeavktlrrsRpqLvenveeYkyiYdvlleav
|
|||||||||
0037934 | (Phosphotyrosine protein) phosphatases II | 995-1230 | 1.2e-43 | 144.8 | In-house | 9-241 (243) | alignment | ||
Range on Protein: 995-1230
Range on HMM: 9-241/243.0
SNLPLVRSDLYLPPDEYRVVLNKktEDFIHASYINGYqeaRSFIVAESPTKLTAAN----FWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPatyDSErH
||. | .|| | ||.|. .|.|.|..|... . .|. |.. | .. || |. .....|||||.. ||... |.|||| ... .
enlsknrysdilpydhsrvkleg..sdyinanliyvt...prliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywp...gev.t
FDFYRIKHHEMNIDNYYTQTILRVLDTQ-AGEEQTIILIQLPLSNivsDELSHTERVGILSAIQEIEKIQRK-------TGNNPILVHCSDTVSRSGVFC
.. .... ... ..||.. |.. .. ......| .. | .. .|. ..|. ..... ...|.||||| |.|.|...
ygdftvtllseehlddytvrtlllenldlddltrlvihyhylpwp...dhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtli
VLYTSIQQMkieqQVNIYEILYNMRTCKPG-LITTPVQYKMVYLLLMRY
..|. .... .|...|.. .|...|| ..|| ||. .| .|. .
aaylmllll....gvdleeavkllreqRpgkavqtpsqyrflyeallel
|
|||||||||
subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 691-936 | 3.4e-43 | 142.5 | In-house | 31-274 (287) | alignment | ||
Range on Protein: 691-936
Range on HMM: 31-274/287.0
EVANCSENKKRNRFKTILPYDNNLLTlrpISSRGDCSHSYINASYIDGYKKKHQFIATQGPLPQTLVDFWRLIWQEDICCILMMLSITSDgGIVRCQQYW
|. . |.||. .||.|.. . .| |. .|||| |. .|.....|||.|||.. |. ||||..... . ...| . . .| .||
kaaeelaavkknryadvlPiddtrvl...lsaegelGsdyinanyvasytddeafiaaqgPiaatvrdfwravletrsasvitmtrevee.arlkcykyw
PDAiGVAAFYGPFKIIVEGiNDNKVSEERIIKLSMTssSSSDNSHKTIHHYLFKCWPDHGVPATPTSTHSFYEQIKMWLDLP------PPVLIHCSGGIG
|. | | . ... |.| | . | . . . .. . . |||.... | . | ..| ..| |...|.. |||
Per.evPmrvGGysvvlld.ydikePeygvralrli..dletrearvvkqldllswPdkvlaPtavglirfvldvkqhielardasevGPlvvhddvGiG
VTGMLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLL
.|.|..... .......| ||| |.| ..| .| ..|. |.... |
rsGillatlvlvsrledlGrvdvaavvirlreyraalvqavvqlrllyealv
|
|||||||||
subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 664-939 | 4.7e-43 | 142.1 | In-house | 12-236 (392) | alignment | ||
Range on Protein: 664-939
Range on HMM: 12-236/392.0
LLNKSNGGKGFKSEFQRLQNfGHLFSTEVANCSENKKRNRFKTILPYDNNLLTLRPISSRGDcsHSYINASYIDGYKKKHQFIATQGPLPQTLVDFWRLI
...| | .||. | . ... . ||. |.|.||.| |||||.. . | | | . |.|||||.... .. .||.||| . .| ||||..
fveknrhsalffeefhdlpg.pdiypqtvaqkeinlkknryknilpydsarvkleviddipd..sdylnasyipsfdnekayiasqgpnaaslddfwrmv
WQEDICCILMMLSITSDGgivrcqqywpdaigvaafygpfkiivegindnkvseeriiklsmtssssSDNSHKTIHHYLFKCWPDHGVPATPTSTHSFYE
.||... | |. . ....|. . | |||..|| .| | .
fqenvttiamvtklkegd.................................................kgddartvaqfhftewPdkdvpkhtssllkfik
QIKMWL-DLPPPVLIHCSGGIGVTGMLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEAF
..| . |..|||| |.| ||..||| . . | |||. .| ..| .| |.||.||| |.. .|| .
evkadfGqythpliihcsagvgrtgvvisidsvvahakktrmvdvfnfvtnirrkrpymvqtkeqyafiygavledl
|
|||||||||
subfamily_PTPRN_pd | Subfamily PTPRN | 675-938 | 1.3e-41 | 137.3 | In-house | 32-291 (297) | alignment | ||
Range on Protein: 675-938
Range on HMM: 32-291/297.0
KSEFQRLQNFGHLFST-EVANCSENKKRNRFKTILPYDNNLLTLRPISSRgdCSHSYINASYI-DGYKKKHQFIATQGPLPQTLVDFWRLIWQEDiCCIL
. |.. | .. || |||. .| |.|| |..||||.. ..|. .|. .. ||||| | | .. .|||||||..|. |||...|.. ....
ekewealcayeaepstkevakaeknvkknrskavlpydhsrvklkeeasa..eksdyinasaildhdprapayiatqgplastvadfwqmvweqG.vvvi
MMLSITSDGGIVRCQQYWPDAiGvAAFYGPFKIIVegINDNKVSEERIIKlSMTSSSSSDNSHKTIHHYLFKCWPDHGVPATPTSTHSFYEQI-KMWLDL
..|. .. |. .|..|||| | .. |. ... . . . ... ... |. . .|. . | ||..||||.. | | .. | .
vnltrleeegvkqckrywpde.G.sevyhiyevhl..vsehiwcddylvr.sfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrGr
PPPVLIHCSGGIGVTGMLISIMIGIEQGLS-TGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEA
|...|||.| | ||. | | . ... | .|..| ....| || ....|..|..|. .. |
scpivvhcsdGaGrtGvyilidlvlnrllkGvkeidiaatlehlrdqrpglvktkdqfefaltavaee
|
|||||||||
0036282 | (Phosphotyrosine protein) phosphatases II | 729-933 | 3.3e-41 | 136.2 | In-house | 3-164 (174) | alignment | ||
Range on Protein: 729-933
Range on HMM: 3-164/174.0
SYINASYIDGYKKKHQFIATQGPLPqtlvdFWRLIWQEDICCILMMLSITSdGGIVRCQQYWPDaigvaafygpfkiivegindnkvseeriiklsmtss
.|||||..|.. .||.||||. ||.......| ...|.|. |...| .|||.
dyinaspldlsyitprliagqgpla.....fwemlkelgittvvmlleeke.lglykcinywpe....................................
sSSDNSHKTIHHYLFKCWPDHGVPATPTsTHSFYEQIKMWLDL--PPPVLIHCSGGIGVTGMLISIMIGIEQGLsTGGVDVMAIVNKMRSQRMNMIQTEE
.. ......||. ||||||| ... ..|..... .| |||.|||.|.| ||.|. ... . ..| .. ||....| ..|.||..|.||..
.lredlerlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtps
QYQFVHY
||.|..|
Qyrflyy
|
|||||||||
subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 1011-1239 | 4e-41 | 136.1 | In-house | 61-288 (318) | alignment | ||
Range on Protein: 1011-1239
Range on HMM: 61-288/318.0
YRVVLN----KKTEDFIHASYINGYQEARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPATydSERHFDFYRIkhhEMNIDNY
|| |. ... |.| |.||.||.. ...| | .| | .|| |. ...||||| ...| . . .||| |... .. |.. .
trvkLqmlegeegsDyinanyidGyrrkkayiaaqaPlpetieDfWrmvWeqnsavivmltqeeergkakvhryWPsk..gsrsygklvv...elkeeve
YTQTILRVLDTQAG-EEQTIILIQLPLSNiVSDELSHTERVGILSAIQEIEKIQRKTGNNPILVHCSDTVSRSGVFCVLYTSIQQMKIEQQVNIYEILYN
... .|| . . ||.. . | . .|| . .. ...|. .....|.|.|.|..||.|||| | | |||... . ....| |. |..... .
lsdyvlrefkvtrteeeesrqvrqyhyts.WpdegvpesgaslldlvrqvskaqqksgagpivvhCsaGvGrtGvfiavdillerikaealvDvfqtvkq
MRTCKPGLITTPVQYKMVYLLLMRYVEEFEAYGN
.|. .. .. | ||...| |. ... .... .
lreqrnlmvqtedqyefiydvllealasgdtevd
|
|||||||||
subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 673-947 | 1.2e-40 | 134.4 | In-house | 17-285 (307) | alignment | ||
Range on Protein: 673-947
Range on HMM: 17-285/307.0
GFKSEFQRLQNFGHLfSTEVANCSENKKRNRFKTILPYDNNLLTLRpisSRGdCSHSYINASYIDGYKKKHQFIATQGPLPQTLVDFWRLIWQEDICCIL
.. ||. | . . | | | ..||.. . |.. . .. | . || | |. | ..||..|||| .| .|| .. ||.. ...
alvdefrvlakktpe.gvtveafsantdknryqdvkcqdkgrivvk...fdg.lasdyihanylgiaikpkkficaqgplentqysfwamaiqekvesvi
MMLSITsDGGIVRCQQYWPDAIGVAAFYG--PFKIIVEGINDNKVS-EERIIKLSMTSSSSSdNSHKTIHHYLFKCWPDHGVPATPTSTHSFYEQIKMWL
|. . . . ..|.|||| | .| | | |. . .|.. .| .|... . . .||.|. .. |||.||| . .. . | ..
mlckvi.elakikceqywpleegqklvfgeapntisvanlgakklapdedlinvttlkvdwa.qksrtiqhlqwenwpdrgvpqinltainlleavrydt
DlppPVLIHCSGGIGVTGMLISIMIGIEQGLSTG-GVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEAFYTIGKESI
. ||..||| |.| .| ...| . .. .. |. .|...|||| |||| || ..| |||| | ||.
n...pvvvhcsaGvGrsGtivaislvqdkmiaGinckdmkklveelrsqrhyaiqteaqylylhrvlleyflelykety
|
|||||||||
subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 967-1227 | 1.4e-40 | 134.0 | In-house | 4-262 (283) | alignment | ||
Range on Protein: 967-1227
Range on HMM: 4-262/283.0
NMNRYEAHYKALQVLTVKPNSVLRNFGLSNLPLVRSDLYLPPDEYRVVLNKKTEDFIHASYIN---GYQEARSFIVAESPTKLTAANFWSMIVKNKCSVI
. | ...... |. |.| . .. . | . | . .| | .|| |. ...|.| |..| |.. . .|.| || . | .|| |. ..| . |
rvnnnklfrevlkrlsvpdldadiasadenkrknrnqeivpadqwrvelksesrdyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekitai
VMLCDIVEMEVDTCYQYWPATyDSERhFDFYRIKHHEMNIDNYYTQTILRVlDTQAGEEQTIILIQLPLSNIvsdeLSHTERVGILSA--IQEIEKIQRK
||| . | . | |||| || . . . .. | ... | . ... ..|..| . . |. | | | . . |..
vmltklqedlrikCsqyWPkr.Gsed.yGeftvtlrkettsnsfiikelll.rvnssakstlllahyqvidW....leygeqaiinslvkfnkvislqte
TGNNPILVHCSDTVSRSGVFCVLYTSIQQMKIEQQVNIYEILYNMRTCKPGLITTPVQYKMVYLLL
. ||.|||| .. |..||. . .|..... | |...... .|| ..... | |||.|. |
skkgPivvhCstgiGrtavfiaasasvkdaltesvvdvfavvkimreqrmmavqtldqyklvhelv
|
|||||||||
subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 653-939 | 1.9e-40 | 133.7 | In-house | 2-279 (439) | alignment | ||
Range on Protein: 653-939
Range on HMM: 2-279/439.0
VKLSEFADHIELLNKSNgGKGFKSEFQRLQNFGHLFST--EVANCSENKKRNRFKTILPYDNNLLTLRPISsrGDCSHSYINASYIDGYKKKHQFIATQG
|. .|| .|.| |.| . . || .|. .. .. .| . .. .||.| . ..| ||. | | |||| ||.|| ... .|||||
vgrdefqehvekldknk.qeifkeifekinstspdyaciaslaaqeydqtknrykdvgafdhtrvtlqeip..gvphshyinanyikGyyddklyiatqg
PLPQTLVDFWRLIWQEDICCILMMLSitsdggIVRCQQYWPDAIgvAAFYGpfKIIVEGINDNKVSEERIIKLSMTSSSSSDNSHKTIHHYLFKCWPDHG
| .| |||||.... |.|. .| .||| ..|| |.| . .. . | . . . . .|. .. . .|||.
pkkettddfwrlviekktvtivmltn......lvesykywpsda..evcyg..diavrvdrnielpnyvirgfkvfnerdttekertvlqfhyiawpdkn
VPATPTSTHSFYEQIKMWLDL--PPPVLIHCSGGIGVTGMLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEAF
||| . | |. | ||..||| |.| || .|.. | .|| . ||. ||. .| || .|.|. || |.. .||
vpaqashvldflrainsandkeeygpvvvhcsagvGrtGtiialdialeqlklenkvdikgivkvlrkqrkqmvqalcqyvfiynavledi
|
|||||||||
subfamily_Ptp69D_pd | Subfamily Ptp69D | 1002-1232 | 2.1e-40 | 133.8 | In-house | 54-287 (307) | alignment | ||
Range on Protein: 1002-1232
Range on HMM: 54-287/307.0
SDLYLPPDEYRVVLNK----KTEDFIHASYINGYQEARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPATydSERHFDFYRIK
.. . |..||.|.| .. |.| ||.|.||.| ..||.| | |. .|| || . .|||| .. |.. . | .||| | ... .|
yedikafDktRvkLkkingkedsdYinasfikgykekkkfiaaqdPveatigDfWRmiaeqevtlivmlsnlteknrkkcakYWpie..devqygdilvk
HHEMNIDNYYTQTILRVLDTQ---AGEEQTIILIQLPLSNIVsDELSHTERVGILSAIQEIEKIQRKTgNNPILVHCSDTVSRSGVFCVLYTSIQQMKIE
. . ..|.. | | .. . .|.. ..| . | |.| |......... . ||.|||| |.|||.| | .||.| |
lvseekhsdyiiReldvskkkeesgevedsrkvvqyhytgWk.DskvPevargllklieqvrelykln.rsPivvhCsaGvgrsgifvaldsllqqlkae
QQVNIYEILYNMRTCKPGLITTPVQYKMVYLLLMRYVE
..|.|.|. ..| .. |.. ||. .| |. | .
dkvdifetvkdLrsqRnllvqsleqYvflyralldyss
|
|||||||||
0043147 | (Phosphotyrosine protein) phosphatases II | 727-933 | 3.7e-40 | 132.8 | In-house | 4-155 (172) | alignment | ||
Range on Protein: 727-933
Range on HMM: 4-155/172.0
SHSYINASYIDGYKKKHQFIATQGPLPQTLVDFWRLIWQEDICCILMMLSItsdggivrcqqywpdaigvaafygpfkiivegindnkvseeriiklsmt
.. ||||||.|.| . ..||||||||. || ||||......| .|... .
gsdyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltel.................................................
sSSSSDNSHKTIHHYLFKCWPDHGVPaTPTSTHSFYEQIKM--WLDLPPPVLIHCSGGIGVTGMLISIMIGIeqglstGGVDVMAIVNKMRSQRMNMIQT
.. .... .||. ||||||| .. .|.|.|. |. |||.|||.|.| ||.|. . . . |... .|. .|..|....|.
.lydpellerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml......lglsleeavalvrekRpgavqn
EEQYQFVHY
..||.|..|
psqyrflyy
|
|||||||||
subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 697-938 | 3.9e-40 | 132.5 | In-house | 6-239 (239) | alignment | ||
Range on Protein: 697-938
Range on HMM: 6-239/239.0
ENKKRNRFKTILPYDNNLLTLRPISSrgDCSHSYINASYIDGYKK-KHQFIATQGPLPQTLVDFWRLIWQEDICCILMMlSITSDGGIVRCQQYWPDAIg
|| .||. |. || . . | .| | ||||||. | . .||||| . . ||||..||| | |.|. . .| .|.|||||.
vnkaknryanivtydhsrvvleklsn..dphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivml.tglieghkkkchqywpdst.
vaAFYGPFKIIvegINDNKVSEERIIKLSMTSsSSSDNSHKTIHHYLFKCWPDHGVPATPTSTHSFYEQI-KMWLDLPPPVLIHCSGGIGVTGMLISIMI
. | ... . .| . ||. . | . . ...| | |||.||| |. . .| | | | .|||| |.| || .. |
..skycnlrvt...lrktevfadyiirtfvms.qvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvida
GIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEA
. | ||.. |. .| .| |.|| ||| |.| .|||
mlrqakkqktvdifnyvkairedrphmvqtseqyvfihlavlea
|
|||||||||
subfamily_PTPRA_pd | Subfamily PTPRA | 1006-1230 | 4e-40 | 132.7 | In-house | 68-294 (330) | alignment | ||
Range on Protein: 1006-1230
Range on HMM: 68-294/330.0
LPPDEYRVVLNKK----TEDFIHASYINGYQEARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPATydSERHFDFYRIKHHEM
|| | ||.|..| . |.| ||.|.||.| .|| | | . | .|| || . | . |||| .. | . . |.|||| . |.. ...
lPydfsrvilsvkeGveesdyinasfidGykekdkfiaaqGPkeetvedfwrmiweqksativmltelkerkeekcaqywPde..GlvtyGnirvevede
NIDNYYTQT--ILRVLDTQAGEEQTIILIQLPLSNIVSDELsHTERVGILSAIQEIEKIQRKTGNnPILVHCSDTVSRSGVFCVLYTSIQQMKIEQQVNI
.. . || ... | .. |... .. |. . . .| .|.|. .....|....... || |||| | |.| |.|| . ....| |..|..
tvlvdytvrkflvqqlpdatrekksrlvrqfhftswPdvGv.PfepiGmlkllkkvkklnqqsag.pivvhcsaGvGrtGtfivldavlervkaerkvdv
YEILYNMRTCKPGLITTPVQYKMVYLLLMRY
.|.. ..|. .| .. | ||...| |. |
fefvkrlrlqrpqmvqtdeqyefiykvlley
|
|||||||||
subfamily_PTPN23_pd | Subfamily PTPN23 | 1002-1234 | 4.1e-40 | 132.4 | In-house | 49-283 (288) | alignment | ||
Range on Protein: 1002-1234
Range on HMM: 49-283/288.0
SDLYLPPDEYRVVLNKKTEDFIHASYINGYQ-EARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPATYDSERHFDFYRIKHHE
| || |. ||.|.....|.| ||.... . .||.. .| . |.. ||.|....| |||||| . |.. . .|||. . .|. ... ..
srdilPyDhnRvklrgskDDYinAsfvkdlspgcPdfiatqaPlqstlnDFWlmvyeqkssviVmllskeelgkpkvdrYwPedkgetvkfgdlsvtlks
MNIDNYYTQTILRVLDTQAGEEQTIILIQLPLSNIVSDELSHTERVGILSAIQEIEKIQRKTGNNPILVHCSDTVSRSGVFCVLYTSIQQMKIEQQ-VNI
. ... . .|.. .| . ... ..|| . | . . .| .... . ... . |..|||| | |.|||...|. ..... .. ..|
vretethvervlkletldadavksvshlqltsWpelGvPasPetllqfldevesayeavqrksktPlvvhCsaGvgRtgvfalvyaavrelekgnglldi
YEILYNMRTCKPGLITTPVQYKMVYLLLMRYVEEF
... .|. . . . |.|..| ......
iqvvsrlreqRrfmvqekeqlkfsyeavleaarrv
|
|||||||||
subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 1007-1236 | 7.7e-40 | 131.9 | In-house | 59-288 (319) | alignment | ||
Range on Protein: 1007-1236
Range on HMM: 59-288/319.0
PPDEYRVVLN----KKTEDFIHASYINGYQEARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPATYDSErhFDFYRIK-HHEM
. | |||| .. |.| ||.|.|||| . || . .| . | .|| |. ....|..|||...|| . .||| . | . . .. .|
aydrtrvvlseldgvegsdyinasfidgyqerekfiatqaPlentiedfWrmvWeeessivvmltklveklkvklkkywpeenfee..yGrlivtleeee
NIDNYYTQTIlRVlDTQAGEEQTIILIQLPLSNIVSDELsHTERVGILSAIQEIEKIQRKTGNNPILVHCSDTVSRSGVFCVLYTSIQQMKIEQQVNIYE
. ..| . . . .....| .| . . . .. .. ..| ...|.| ..|| . || ||||. | | | |.|| ....| |. .....
eledyiirkl.kl.nkkssevetRevkhfqyteWpdhdv.PekatslldllkrirksrektqsgPivvhCsaGvGRtGtfivldamlervkeegvlDvfs
ILYNMRTCKPGLITTPVQYKMVYLLLMRYVEEFEA
. ..|| .. .. .| |||..| |. .|| ...
tvsrlRtqRnimvqrpeqYkfiyealleaveagdt
|
|||||||||
subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 693-937 | 8.5e-40 | 131.4 | In-house | 3-239 (239) | alignment | ||
Range on Protein: 693-937
Range on HMM: 3-239/239.0
ANCSENKKRNRFKTILPYDNNLLTLRPISSrgDCSHSYINASYIDGYKK-KHQFIATQGPLPQTLVDFWRLIWQEDICCILMMlSITSDGGIVRCQQYWP
|. || .||. |. || . . | .| | ||||||. | . .||||| . . ||||..||| | |.|. . .| .|.||||
akkrvnkaknryanivtydhsrvvleklsn..dphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivml.tglieghkkkchqywp
DAIgvaAFYGPFKIIvegINDNKVSEERIIKLSMTSsSSSDNSHKTIHHYLFKCWPDHGVPATPTSTHSFYEQI-KMWLDLPPPVLIHCSGGIGVTGMLI
|. . | ... . .| . ||. . | . . ...| | |||.||| |. . .| | | | .|||| |.| || ..
dst...skycnlrvt...lrktevfadyiirtfvms.qvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgafl
SIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLE
| . | ||.. |. .| .| |.|| ||| |.| .||
vidamlrqakkqktvdifnyvkairedrphmvqtseqyvfihlavle
|
|||||||||
subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 696-937 | 5.6e-39 | 128.8 | In-house | 1-237 (237) | alignment | ||
Range on Protein: 696-937
Range on HMM: 1-237/237.0
SENKKRNRFKTILPYDNNLLTLRPISSRgdcsHSYINASYIDGYKK-KHQFIATQGPLPQTLVDFWRLIWQEDiCCILMMLSITSDGGIVRCQQYWPDAI
|||| .||. | || . . |. | ||||.|..|. ...||.|||| . |||...||| | ...||. .| ..| .|||..
senkiknrygnivaydhsrvvlkgagsg....sdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqek.csvivmltgliegnelkchkywpstd
GvAAFYGPFKIIVegINDNKVSEERIIKLSMTsSSSSDNSHKTIHHYLFKCWPDHGVPATPTSTHSFYEQIKM---WLDLPPPVLIHCSGGIGVTGMLIS
| || . . . ... |. . | .. . . . || | | .|||.||| .. | .| . | .|||| |.| ||...
q.paaygvltvsl..kkkeefsdytvrsllls.krltlkevrlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflv
IMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLE
| . | ||. | . .| .|||..|| |.| ..||
idamlrqakekkvvdiynyvysieedrpyiiqtkdqyvfihqtile
|
|||||||||
subfamily_PTPN3_pd | Subfamily PTPN3 | 1005-1229 | 1.4e-38 | 127.4 | In-house | 50-273 (280) | alignment | ||
Range on Protein: 1005-1229
Range on HMM: 50-273/280.0
YLPPDEYRVVLNKKTEDFIHASYINGY----QEARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPATYDSERHFdFYRIKHHE
|| |. || |.. . |.| |.|.| . .|.. | . ||..|| |. ..|.|.|||| ..|| |.|||| | |. .. ...| ..
ilpydatrvklkesetdyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqksslivmlttlverGrvkChqyWPetedeleyg.efsvkcek
MNIDNYYTQTILRVLDTQAGEEQTIILIQLplsNIVSDELSHTERVGILSAIQEIEKIqRKTGNNPILVHCSDTVSRSGVFCVLYTSIQQMKIEQQVNIY
. .. | | . |... ||..|. .| .|. .. .|. .....|. |.. ..|..|||| . |.||. .| |... . ....|..
edetksyvlrelvlkdketkeerkilqlqy...laWpdhgvPddsadflefvervrkl.rsgkeePvvvhCsaGigrtGvlilletalalieaaepvypl
EILYNMRTCKPGLITTPVQYKMVYLLLMR
.|. .|| . |. |. |||.| ...
divrtmrdqramlvqtasqykfvCeailk
|
|||||||||
subfamily_PTPRG_pd | Subfamily PTPRG | 1016-1232 | 2.4e-38 | 126.7 | In-house | 72-288 (563) | alignment | ||
Range on Protein: 1016-1232
Range on HMM: 72-288/563.0
NKKTEDFIHASYINGYQEARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPAtyDSERHFDFYRIKHHEMNIDNYYTQTILRVL
.||. |.| |.||.||| .. ||.. | | |. || || .. ..|||. ..|| . | .|||. | ... ... | .. .||. | .
kkkklDYinAnyidGyqkskafiatqgplkdtfddFWrmiWeqnvaiivmitnlvergrrkcdvYWPk..desetygalqvtlieeevlalytvrtlvik
DTQAGEEQT----IILIQLPLSNIvSDELSHTERVGILSAIQEIEKIQRKTgNNPILVHCSDTVSRSGVFCVLYTSIQQMKIEQQVNIYEILYNMRTCKP
... ... .| .. | . . . |. .. .. .... ||.|||| |.|.|...|| | ..|.. |..||....| .|. ..
nlklkkkkqcdteklvrqyhytkW.PdhgvPehslpvLifvkkssaankae.aGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRn
GLITTPVQYKMVYLLLMRYVE
|..| || .. |. .
flvqteEqYiflhdalleaia
|
|||||||||
subfamily_PTPN12_pd | Subfamily PTPN12 | 1006-1232 | 3e-38 | 126.4 | In-house | 50-278 (290) | alignment | ||
Range on Protein: 1006-1232
Range on HMM: 50-278/290.0
LPPDEYRVVLNKKT----EDFIHASYINGYQEARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPATYDSERHFDFYRIKHHEM
|| |. ||.|.|.. .|.| |..|.| .. ..| | .| | .|| || . . ...||.| .||.. | .||| . ..| .|. .... .|
lPydksrvelskieeeegsdYinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCerYWpeegeeelefgefevtleee
niDNYYTQTILRVLDTQAGEEQTIIlIQLPLSNIVsDELSHTERVGILSAIQEIEKIQRkTGNNPILVHCSDTVSRSGVFCVLY---TSIQQMKIEQQVN
.. . ..| | .| .|. .. |. . | . .|. |......|. . ..|..|||| | | |. ... . ... ||.....
..kavdddflirtLkveaqkesrkv.yqfhYtaWP.DhgvPssaksllelielvrelqe.sedaPlvvhCsaGvGrtGtiiaidyvrellkaekipeeld
IYEILYNMRTCKPGLITTPVQYKMVYLLLMRYVE
..... ..|. .. |. | ||..|| .. .|.
vfdlvlelrkqraalvqtkeqyelvykavaelvq
|
|||||||||
subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 673-937 | 4e-38 | 125.9 | In-house | 7-257 (267) | alignment | ||
Range on Protein: 673-937
Range on HMM: 7-257/267.0
GFKSEFQRLQNFGHLFST-EVANCSENKKRNRFKTILPYDNNLLTLRPISSRgdcshsYINASYIDGYKKKHQFIATQGPLPQTLVDFWRLIWQEDICCI
.. ||. ... . || ..|..|||. ||||.. . || ||||||..|||.|..||.||.|| .| ||. .| .... |
eiekefelikkisdtsstisqsiaeknqernrlddnlpyddtrvilrtkeee......yinasyvegyktknafivtqdplkntitdfltvihdqkvpvi
LMMlSITSDGGIvrcQQYWPDAIGVAAFYGpfKIIVEGINDNKVSEERIIKLSMTSSSssdNSHKTIHHYLFKCWPdHGVPATPTSTHSFYEQIKMWLDL
.. .. . | ...|| .| | | . || ... . .|| | . .| . . | .| | . | | | |.
vll.tkvftdni...rlfwPPkmgqakkyq..dltvehslekeendyqiitlelkfkn...esahnvtlyyykkwn.intnnkpylkplfgilaknqlen
-PPPVLIHCSGGIGVTGMLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLE
.|....|| |.| .| .. | .|. | .|. . |.||||. ...| |.| ..| .| |
gnrPlvvacsdGvGrsGtflvidsqleraktegvsdifdflrkirsqriglvdtkeryiyihellae
|
|||||||||
subfamily_PTPN9_pd | Subfamily PTPN9 | 1009-1233 | 8.9e-38 | 125.0 | In-house | 55-292 (297) | alignment | ||
Range on Protein: 1009-1233
Range on HMM: 55-292/297.0
DEYRVVLNKK----TEDFIHASYINGYQEARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPATYDSERHFDFYRIKHHEMNID
|| ||||.|. . |.|.|....||.. ..|| . | | | .|| |. ... |||| .||. | |||| . .| .| ...... |..
detrvvlakvdedeasdyinanfvdGykqkkafiatqGplkktvsdfWrmvWeqevlvivmttrvvergrlkcgqyWpleeessaefgdlsvsnveveee
NYYTQTILRVLDTQAGEEQTIILIQL--------PLSNIVSDELSHTERVGILSAIQEIEK-IQRKTGNNPILVHCSDTVSRSGVFCVLYTSIQQMKIEQ
. |....| . ... .|..... |. | | .. .. | .|..|. . . .. . ||.|||| . |.| |. | ...... ..
edykvrvleiknvkteesrkvthfqflsWPdyGvPssaaslldvlekvrekqalavkelgdewkghpsgPPivvhcsaGiGrtGtfitldiclsrleevg
QVNIYEILYNMRTCKPGLITTPVQYKMVYLLLMRYVEE
.|.. | . .|| . | || ||.. || .. | |
tvdvvetvkllrtqrafsiqtpeqyefcylavleyale
|
|||||||||
subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 972-1232 | 2e-37 | 123.7 | In-house | 9-260 (267) | alignment | ||
Range on Protein: 972-1232
Range on HMM: 9-260/267.0
EAHYKALQVLTVKPNSVLRNFGLSNLPLVRSDLYLPPDEYRVVLNKKTEDFIHASYINGYQEARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVE
| .. .. .. . . . .. | | | || |. ||.| .|.|..| |||..||. . ||| . | | | ..|. .| ..|..|||.| . .
ekefelikkisdtsstisqsiaeknqernrlddnlpyddtrvilrtkeeeyinasyvegyktknafivtqdplkntitdfltvihdqkvpvivlltkvft
mevDTCYQYWPATYDSERHFDFYRIKHHEMNIDNYYtQTILRVLDTQAGEEQTIILIQLPLSNIVSDELSHTER-VGILSaiqeieKIQRKTGNNPILVH
| ..|| .... ..| . .| | | | | . . . | || ... . . .|||. | | . ||.|..|.
...dnirlfwPPkmgqakkyqdltvehslekeendy.qiitlelkfknesahnvtlyyykkwnintnnkpylkplfgila......knqlengnrPlvva
CSDTVSRSGVFCVLYTSIQQMKIEQQVNIYEILYNMRTCKPGLITTPVQYKMVYLLLMRYVE
||| | ||| | |... ....| |. ..|.. | ..| ..||. | .| .. || | |
csdGvGrsGtflvidsqleraktegvsdifdflrkirsqriglvdtkeryiyihellaeyae
|
|||||||||
subfamily_CG7180_pd | Subfamily CG7180 | 967-1231 | 3.4e-37 | 122.7 | In-house | 11-290 (296) | alignment | ||
Range on Protein: 967-1231
Range on HMM: 11-290/296.0
NMNRYEAHYKAL--QVLTVKPNSVLRNFGLSNLPLVRSDLYLPPDEYRVVLNK----KTEDFIHASYINGYQEARSFIVAESPTKLTAANFWSMIVKNKC
....... || . .. ... . . .. |. | .|.| ||||.| ...|.| |.|.... . .|| | |.| | .||... ....
krrkfrveyklelkltprleigdCagglrkenreknrdvkvvPyDynRvvLekldGeeksdYinavyvdsflkkkeyivteapkketvdefWrlvydeei
SVIVMLCDIVEMEVdTCYQYWPATYdserHFDFYRIKHHEMNIDNY--YTQTILRVLDT----------QAGEEQTIILIQLPLSNI-VSDELSHTervG
| .|.|.. ... . .||| . .... | . .. ..| .. ... . |. .. |.|| .. . || . .
savvvLtktfdfak.mypsywpnks....keqygeifveiveekqyanlkirtfkltkkivalteqekqvkaetRivklfqlteWeledkvPlstn...a
ILSAIQEIEKIQRKT----GNNPILVHCSDTVSRSGVFCVLYTSIQQMKIEQQVNIYEILYNMRTCKPGLITTPVQYKMVYLLLMRYV
.. .. ......|. ..|..|..|| .|||||.. . .......|..|...| . .| .|.|. . .|| .| .| .|
lielrrrvrlwrekvdedpeegPvvvvssdGasRsGvylaidanlelvekeeevdvFeavktlrrsRpqLvenveeYkyiYdvlleav
|
|||||||||
0051429 | (Phosphotyrosine protein) phosphatases II | 729-941 | 3.5e-37 | 123.9 | In-house | 5-227 (272) | alignment | ||
Range on Protein: 729-941
Range on HMM: 5-227/272.0
SYINASYIDGYKK---KHQFIATQGPLPQTLVDFWRLiWQEDICCILMMLSITSdGGIVRCQQYWP----------DAIGVAAFYGPFKIIVEGINDNKV
.||||....|| . .. .....|||| | ||||| ....| .|... | . | . | .||| | .|| . ... . .
gyiNardvggygrvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeE.rgrlkcdrywpgirylhlpilddsaptilygalrvtllseellld
SEERIIKLSMTSSSSSDnshKTIHHYLFKCWPDHGVPATPtsthsFYEQIKMWLDlPPPVLIHCSGGIGVTGMLISIMIGIeQGLS-TGGVD--------
| . |....| . ...|... ||||||| . . | ... || . |||.|||.|.. ||... . . . .|.| . ||
yilrellltlllsagea...revmhlhytdwpdhgvpqea.....llellellld.ggpvlvHCsaGkdRTGtvvalllll.lgvsletivddYlltnly
VMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEAFYT
. ..|...|.||....||||||.|.. .|||....
leeaveelraqrpgavqteeqylflyeallellrs
|
|||||||||
subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 1001-1233 | 3.5e-37 | 122.9 | In-house | 25-266 (270) | alignment | ||
Range on Protein: 1001-1233
Range on HMM: 25-266/270.0
RSDLYLPPDEYRVVLNKKT----EDFIHASYINGYQE-ARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPATYDSERHFDFYR
|. || . ||.|.. . .| | |..|... ...| | .|.. | .|| ||...| . |||. ...| . | .|||| ... .. .
RyadiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkekvkledgk
IKHHEMN--IDNYYTQTILRVLdtQAGEEQTII---LIQLPLSNIVSDELSHTERVGILSAIQEIEKIQRKTGNN-PILVHCSDTVSRSGVFCVLYTSIQ
|| .. .. | .| ||. . |||. .. . | ....| | .. .|. .... . .... .. |.|||||. | |.|.. .| . ..
ikvlalseekeegyiltrlrle..ekgeerrlvHfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcsaGvgRtGtlialDiavr
QMKIEQQVNIYEILYNMRTCKPGLITTPVQYKMVYLLLMRYVEE
.. ...|.. .|. ..| .. |. .|.||...| .. |.|
lLeetkkvdvlaiieelRkdRmalvqhpeqyeflykavveyaer
|
|||||||||
0049772 | (Phosphotyrosine protein) phosphatases II | 690-942 | 4.1e-37 | 124.0 | In-house | 38-283 (314) | alignment | ||
Range on Protein: 690-942
Range on HMM: 38-283/314.0
TEVANCSENKKRNRFKTILPYDnNLLTLrPISSRGDcsHSYINASYIDGYkkkHQFIATQGPLPQTLVDF----------WRLI--WQEDICCILM----
. ||. .|...||.. |||.| |. | | . . ..||||||.||. .||||||||. |.||| ||.. .. .. | |
ilvadlflnrdknryldilpad.nrvil.pglpvsg..sdyinasyvdgf...lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivmsrde
-----------------MLSITSDGgivrcqqywpdaigvaafygpfkiivegindNKVSEERIIKLSmtsSSS--SDNSHKTIHHYLFKCWPDHGVPaT
|... | | ..... | . . ... .|| .||...| .
vladelsrLdaAlgKtpllildgng...............................neptaadlellk...eelydpelferlgikylripvpDgsap.l
PTSTHSFYEQIKMWlDLPPPVLIHCSGGIGVTG--MLISIMIGIEqglstgGVDVMAIVNKMRSQRM-----NMIQTEEQYQFVHYVLLEAFYTI
. .|.| |. . | . |||.||..|.| || ... ... ||.. ... .|..|. ..|.. |||.|....|||.. ..
ledfdeflefieea.dkggpvlvHCkaGkgRtgtfvvaaylmkll......gvsleealedvrlkRpinpnpgfieqleqyefilealleylkfl
|
|||||||||
subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 680-937 | 5.7e-37 | 121.9 | In-house | 36-281 (290) | alignment | ||
Range on Protein: 680-937
Range on HMM: 36-281/290.0
RLQNF--GHLFSTEVANCSENKKRNRFKTILPYDNNlltlRPISSRGDcSHSYINASYIDGYKkkHQFIATQGPLPQTLVDFWRLIWQEDICCILMMLSI
.|. . .. . .. . . |.||.| . | | | . | |. | |..| | || |||.| .| .|.||.. ||.. | |. .
klkpylpvqylerkifdkntefkknrykdvvcndkt....rvilkdGy.dGdyvhanyvkGlk..amfiltqGalkdtvidiwrmvlqekvaaivmlcel
TSDGgIVRCQQYWPDAIGVAAFYGPFKIIVEgINDNKvsEERIIKLSMTSSS-SSDNSHKtIHHYLFKCWPDHGVPatpTSTHSFYEQIKMWLDLPPPVL
|| .|.||.|. | . .| . .. .|.| ...||| .. | .|| ..|. |.|||. |. || .. ... .. ||
iedG.kakceqyypekeGevltfGeitvlcs.eeddk..daniikktlsvrdkdsGkehk.lkhlkikswpdksva...lstlallrtlrilrkasGpvv
IHCSGGIGVTGMLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLE
.||| ||| || ...| .|.. | .|.. .| .| |.| .| . || . .||.
vhcsaGiGrtGtfvaievglqilldGkeldlldlvralrnsrlnsvqvdiqylalveilld
|
|||||||||
subfamily_PTPRK_pd | Subfamily PTPRK | 1005-1225 | 6.1e-37 | 122.1 | In-house | 52-271 (314) | alignment | ||
Range on Protein: 1005-1225
Range on HMM: 52-271/314.0
YLPPDEYRVVLNKKTE----DFIHASYINGYQEARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPAtyDSERhFDFYRIKHHE
|..| ||.| . |.| |..|..|. .. |||. | . | ..|| .. ...|. |||| ..|| |..||| |.| .. ... |
ilaydrsrvflitidgdpssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasivmltelvevgrvkClkyWPe..dtev.ygdikvelve
MNIDNYYTQTILRVLDTQAGEEQTIILIQLPLSNIVSDELShTERVGILSAIQEIEKIQRKtGNNPILVHCSDTVSRSGVFCVLYTSIQQMKIEQQVNIY
..... . . |.|| .. | |.. .. |. . . . ... |.|. .....| | . .. .|.|||| |.|.|... . .. .. |. |...
tellaelvvrifrveklargqeeirevrqfqflgWpdhdvP.vsatgllklvrrvkksqee.eaGrivvhCsaGaGrtGtfiaidivldmieregvvdvf
EILYNMRTCKPGLITTPVQYKMVYL
.. ..|. |. .. | |||..|
navktlrsrkvnmveteeqykfiyd
|
|||||||||
0046846 | (Phosphotyrosine protein) phosphatases II | 725-937 | 1.5e-36 | 121.1 | In-house | 9-171 (176) | alignment | ||
Range on Protein: 725-937
Range on HMM: 9-171/176.0
DCSHSYINASYIDGYKkkhqFIATQGPLPQTLVDFWRLIWQEDICCILMMLSITsDGGIVRCQQYWPDAIGVAAfygpfkiivegindnkvseeriikls
| . .||||..|.|.. .||||||||.|| ||........| ....... . . | ..| .|||. ..
dldldyinanlilgsr....piatqgplprtladflemlkelgitavvnlteev.elgrlkcpnywpeleklgi..........................
mtsssssdnshktihHYLFKCWPDHGVPATpTSTHSFYEQIKMWLDLPPPVLIHCSGGIGVTGMLISIMigieqGLS-TGGVDVMAIVNKMRSQRM-NMI
.||. ||||||| . ....|.|. .|. |||.|||.||| ||.|. . | |..| .. ..|.||. ...
...............qylhlpwpDhgvpdl.elllellefirealkeggpvlVHCsaGigRtgtlvaay.....llelekglsveealalvreqRplgav
QTEEQYQFVHYVLLE
||.|||.|.....|.
qtpeQyrflyefell
|
|||||||||
subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 1010-1233 | 1.7e-36 | 120.8 | In-house | 55-278 (281) | alignment | ||
Range on Protein: 1010-1233
Range on HMM: 55-278/281.0
EYRVVL----NKKTEDFIHASYINGYQEARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPaTYDSERHFDFYRIKHHEMNIDN
||.. ..|. |.| |....||.. . .|....| . ..|| |....| |.|||. .| . |..||| .|| .. ...|... . .
atrvkvtpneenkntDYinanfvpgykgekeyiatqgPvPaslvafWqmvweqkvsaivmvtreieagklkChrYWP.ddnselkygdvtvkstaeeeka
YYTQTILRVlDTQAGEEQTIIliQLPLSNIvSDELSHTERVGILSAIQEIEKIQRKTGNNPILVHCSDTVSRSGVFCVLYTSIQQMKIE-QQVNIYEILY
| . ... ... ||.... || . | .. .|. .|..|...| . |...||| | |.|.. | . ..... | ..... ...
tyierkfkl.eresgetreve..qlaytaW.PdhGvPattkellefrkevlkltekktkaplvihCsaGvGrtGtyialDrlvkaveaeleeldvkavva
NMRTCKPGLITTPVQYKMVYLLLMRYVEE
..| . .. | |||. ||. .......
elrkernlmvqtvvqyefvykavldaldk
|
|||||||||
subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 995-1231 | 2.7e-36 | 120.1 | In-house | 46-279 (288) | alignment | ||
Range on Protein: 995-1231
Range on HMM: 46-279/288.0
SNLPLVRSDLYLPPDEYRVVLNK----KTEDFIHASYINGYQEARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPATYDSERH
| . | || || || |.| ...|.| ||||.|... . .| . .| | .|| .. || | |||| ..|| . .| .|||.. . ...
vnakknRyrnilpyDekrvklkkleeeagaDYinasyidgekkkkkyiatqgPladtvndfWelvyenktstivmltelveggktkCeeYWPdadkpkny
FDFYRIKHHEMNIDNYYTQTILRVldtQAGEEQTIIliQLPLSNIVSDELShTERVGILSAIQEIEKIQRKTgNNPILVHCSDTVSRSGVFCVLYTSIQQ
.. . .. . ... ....| . . ..| .| |. . .. .| .. .. . . .||.||||. | |.|.| .| . |..
Gsvtvtlveskeledfvlrkllle...kkkteleit..qyqylaWpdhgvP.eskapllellrqvkvanqad.tgpiivhCsaGvGrtgtFialdalida
MKIEQQVNIYEILYNMRTCKPGLITTPVQYKMVYLLLMRYV
.. |..... ... ..| .. |. | || .| |. .
veeedyiDvagtvaklRkqRallvqtlkqYefiyevllsli
|
|||||||||
subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 670-939 | 3.9e-36 | 119.3 | In-house | 20-287 (305) | alignment | ||
Range on Protein: 670-939
Range on HMM: 20-287/305.0
GGKGFKSEFQRLQNFGHLFSTEVANCSENKKRNRFKTILPYDNNLLTLrpissRGDCSHSYINASYIDGYKKKHQFIATQGPLPQTLVDFWRLIWQEDIC
| .|...||. .. | . . ......||.| . ||| . | .| | || | |. . ..|| || || .| ||| . .|. .
gpaglraefvamkrfndfekmkafkeaqeagknrykdvgcldnnrvkl.....egpwpheyihanyvstptnpkrfictqaplektcadfwymclqdkve
CILMMLSITsDGGIVRCQQYWPDAIG-VAAFY-GPFKIIVEGINDNKV-----SEERIIKLSMTSSSSSDNSHKtIHHYLFKCWPDHGVPATPTSTHSFY
|.|. . . | .|..|.. . | | . ||.| ... .. .. . .. . ...| . || . ||| ||||. .. .
aifmlcnll.ekgakkcleyfaskdkdvlefeekgqkisvkfessvtlkfrkdakakvtetvlviegpgekark.vthyhwidwpdrgvpaadlailell
EQIKMwldLPPPVLIHCSGGIGVTGMLISIMIGIEQGLSTGGVD-VMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEAF
|. . . |. .||| ||| || .. . ..| |. .. |..|.| || | |||..|| ||| |.|. |
ekarp...skgpivvhcsagigrtgsvvmleyildqllagqiiedtdkilqkireqrnnsiqtdaqylfvhqvilnyf
|
|||||||||
subfamily_PTPRB_pd | Subfamily PTPRB | 1006-1233 | 5.1e-36 | 119.2 | In-house | 61-287 (293) | alignment | ||
Range on Protein: 1006-1233
Range on HMM: 61-287/293.0
LPPDEYRVVL----NKKTEDFIHASYINGYQEARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPATYDSERHFDFYRIKHHEM
|| |. || | .....|.| |.||.||. | ||.. | | .|| |. ..|.|.|||| ..|| | .||||.... . | .|
lpydhsrvkLaalkdesgsDYinanyipgynsprefiatqGPlpetvddfWrmvwekkssiivmltqlvekgkvkCeeYWPadeepvlyGdikvtlvaee
NIDNYYTQTilrvLDTQAgEEQTIILIQLPLSNIVSDELShTERVGILSAIQEIEK-IQRKTGNNPILVHCSDTVSRSGVFCVLYTSIQQMKIEQQVNIY
. ... ... | . |... . |. . . . .|. ...... |.... ..||.|||| | |.|.| | . .|... |. |.|.
eledwvire....lkiek.ekeerkvrqyhftsWpdhgvP.ektktlldfvrtvreaiektaskrPivvhCsaGvGRtGtfialdrllqaieeedyvdif
EILYNMRTCKPGLITTPVQYKMVYLLLMRYVEE
|....|. . |. | || ... .......
givaelReeRnllvqtekqYifihqcvldllrk
|
|||||||||
subfamily_PTPN6_pd | Subfamily PTPN6 | 949-1233 | 7.5e-36 | 118.7 | In-house | 6-299 (306) | alignment | ||
Range on Protein: 949-1233
Range on HMM: 6-299/306.0
PSNLQLIVKRLGKHDEILNMNRYEAHYKALQVLTVKpNSVLRNFG--LSNLPLVRSDLYLPPDEYRVVL---NKKTEDFIHASYINGYQ--EARSFIVAE
..... |..| |..| |. . .| ....|| .| . . |. | .| | || |. ||.| . . .|.| |.||.. . . .|.| ..
akeieqrvselekeeeslekagfeeefeelqqeeak.kllsrkegakpenkeknryknilPfDhtrvilkepsvpgsdyinanyikkevkgsdksyiatq
SPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPATYDSERhFDFYRIKHHEMNIDNYYTQTILRVLD-TQAGEEQTIilIQLPLSNiVSDEL
. | ..||.|...... ||||. || . |..|||.. ..|. . ..... . . ..|. |.| ....||... .|. . |.
gclettvsdFWrmvwqensrvivmttkevErgkekCarYWPdeeekee.yGkisvtnvseksladYilRelsvskkkkkkeerev..fqyhfks.WPdhg
SHTERVGILSAIQEIEKIQRKTG---NNPILVHCSDTVSRSGVFCVL---YTSIQQMKIEQQVNIYEILYNMRTCKPGLITTPVQYKMVYLLLMRYVEE
... .|. ...... |... . ||.||||. . | | | |. |.. ... ...|... .|. . ||. | |||.|| . |.|.
vpkdpgavLdfledvnrkqeeleeaeagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqteqqykfvykaikkyiet
|
|||||||||
subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 1006-1233 | 2.4e-35 | 116.9 | In-house | 38-270 (274) | alignment | ||
Range on Protein: 1006-1233
Range on HMM: 38-270/274.0
LPPDEYRVVLNKK-----TEDFIHASYINGYQE-ARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPATYDS---ERHFDFyRI
|| .. ||.|... ..| | || ||.| . .. . | | |.|| || .....||||| .. |.. . | .|.| . | ||. |. |
lPnensrvllesessededssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneqkCavyfPdaedyeiserygdv.ei
KHHEMNIDNYYTQTILRVLDTQAgeEQTIILIQLPlsnIVSDELSHTERVGILSAIQEIEKIQRKTGNN--PILVHCSDTVSRSGVFCVLYTSIQQMKIE
| .... | |. . | .. .. |.... . . |. | . .|. ..|.|. .... .. |..|||| . | |.| ...|.. |
kvekiverndysvrklvlkyler..ersvkhywyt...dWPdhksPddantlldlvleveesreeenaklapvvvhCsaGiGrtGcfiaisiavrqlree
QQVNIYEILYNMRTCKPGLITTPVQYKMVYLLLMRYVEE
. |.. .| |.| . |.. | ||.... |. |...
ivvdvlkivcnlrldrGGmvqtseqyelihralclylkr
|
|||||||||
subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 1007-1231 | 3.3e-34 | 113.5 | In-house | 59-288 (325) | alignment | ||
Range on Protein: 1007-1231
Range on HMM: 59-288/325.0
PPDEYRVVLNKKT----EDFIHASYINGYQEARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLcDIVEMEVDTCYQYWPATYDSERHFDFYRIKHHEMN
. |. ||||. | |.| |||.. ... |. | .| | ..| ... .|||.|.| .... . | | .||| ..| ..| ..
aldksrvvletkkddpssdyinasylrddkkkdvflaaqaPltatindlWrlvldWrcsvvvvl.neldlgkdrcavywpkemgksktfGglevklrtie
IDNYYTQTILRVLDTQAGEEQTIILIQLPLSNIVSDELSHTERVGILSAIQEIE-KIQR-KTGNNPILVHCSDTVSRSGVFCVLYTSIQQMKIEQQVNIY
| . .| | ... || ... || . . . . . || ..... ... . |||||||. | |.||| ||. .... | .|.|.
eisdyvhrvldvkqvkkGetrsvkqfqlqswddmGvqkrpatlisilqlvkavservtantkastpilvhcsaGvGrtGvfislysalakvieesrvdif
EILYNMRTCKPGLITTPVQYKMVYLLLMRYV
. . ..| .| .. | || ..| |. ..
gfvkklrkdrpsmvetvdqyiliyealveay
|
|||||||||
0049260 | (Phosphotyrosine protein) phosphatases II | 735-933 | 4.8e-34 | 112.6 | In-house | 1-144 (152) | alignment | ||
Range on Protein: 735-933
Range on HMM: 1-144/152.0
YIDGYKKKHQFIATQGPLPQTLVDFWRLIWQEDICCILMMLSITSdGGIVRCQQYWpdaigvaafygpfkiivegindnkvseeriiklsmtsssssdns
.||||.....|||||||.|.|| ||||.... .| .|.|. . . | . | ||.
fidgyampfefiatqgpgpntladfwrmlkelgittivmltelle.lgklkceqyi............................................
hktihHYLFKCWPDHGVPATPTSTHSFYEQIKM-WLDLPPPVLIHCSGGIGVTGMLISIMIGIeqglstGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHY
.||. ||||||| . ... |. .|| |||.|||.|.| ||.|. . . . ||.. .|. .|..|........|..|...
.....qylhlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpgqlrflye
|
|||||||||
subfamily_PTPN1_pd | Subfamily PTPN1 | 1006-1228 | 1.2e-33 | 111.1 | In-house | 42-268 (290) | alignment | ||
Range on Protein: 1006-1228
Range on HMM: 42-268/290.0
LPPDEYRVVLNKKTEDFIHASYINGYQEARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPATYD-SERHFD--FYRIKHHEMN
| | |..|... |.| || .. . ||.|.. | |.. || |. ..|. .||| .|| | |.|||| . .| .. ...| . .
spydhsrikleradndyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvvekeqikcaqywPqgeeekellledtklkvklisee
IDNYYTQTILRVLDTQAGEEQTIILIQLPLSNIVSDELSHTERVGILSAIQEIEKIQRKTGnnPILVHCSDTVSRSGVFCVLYTSIQQMKIEQQ---VNI
. .||| .|.. . .. | ..|. . . | . . | ..| .... | | ..||| . ||| ||.. | . ... ... |.|
rksyytvrllelenlktqetreilhfhyttwpdfgvpespaaflkflfkvresGslssdvG..pavihcsaGiGrsGtfclvdtclvliekkddlssvdi
YEILYNMRTCKPGLITTPVQYKMVYLLLM
. | ..| . ||| |. | .. || ..
kkvllelrkyrlGliqtadqlrfsylail
|
|||||||||
subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 996-1230 | 1.4e-33 | 111.1 | In-house | 44-276 (315) | alignment | ||
Range on Protein: 996-1230
Range on HMM: 44-276/315.0
NLPLVRSDLYLPPDEYRVVL----NKKTEDFIHASYINGYQEARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPATYDSERHF
| . | . || |. ||.| .. .|.| ||||..... ...| . | | . .||.|....| . |||. . | . | |||| .|
nfkknryknilPldsarvkleviddsPdsdyinasyiksvdddkayiasqgPlkasvddfwrmvlqekvttivmvtkkqegdkikcrqywPdrkadsvef
DFYRIKHheMNIDNYyTQTILRVLDTQAGEEQTIIlIQLPLSNIvSDELSHTERVGILSAIQEIEKIqRKTGNNPILVHCSDTVSRSGVFCVLYTSIQQM
.... .... |... | | |. .||. . | . . |. . . .| |.|. ... . ..||||| | |.||.. . ..|.
Gsikvel..lslead.tdgvarklvtrkseesrtv.tqfqftew.PdkGvdkqtssllklikevkad.ngkkefsllvhcsaGvGrtGvvisidevvaqi
KIEQQVNIYEILYNMRTCKPGLITTPVQYKMVYLLLMRY
| .. |...... |.|. .| |. | .| ..| .. .
krtrsvdvfnfvknlrakrpylvqteeeyafiydavled
|
|||||||||
subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 1003-1231 | 3.2e-33 | 110.1 | In-house | 58-284 (297) | alignment | ||
Range on Protein: 1003-1231
Range on HMM: 58-284/297.0
DLYLPPDEYRVVLNKKTE----DFIHASYINGYQEarSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVdTCYQYWPATYDSErhfdFYRIKH
|| | || |. . |.. ||...|... .| . | | | |.|| |..... |.|||| | | . | .||. . .. | .
kniLPydssRvkLaivnddpdsDyvnasfvkgnkh..rlittqmPmkatvadfWamvldeqvstivmlnddnerdk.kcaryWsdkgvtt....fGdvsv
HEMNIDNYyTQTILRVLDTQAGE-EQTIILIQLPLSNIVSDELSHT-ERVGILSAIQEIEKIQRKTGNNPILVHCSDTVSRSGVFCVLYTSIQQMKIEQQ
. ... . | | |. . |. .. .. | . ... . . .| |.|..| .. ..|.||||. | | ||.. . . ..| |..
vllsvser.eGfikrelevtkgkakarrvvkqyqfveWPdkaverkdsassllklisevrkdfsqnaegPllvhclaGvGrtgvlltidsvvaeakreke
VNIYEILYNMRTCKPGLITTPVQYKMVYLLLMRYV
|.|.... .| .| |. | |||.|| ... ..
vdifglvkklrqerpylvqtkeqykfvyvavleal
|
|||||||||
subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 1018-1229 | 1.9e-32 | 107.9 | In-house | 51-253 (284) | alignment | ||
Range on Protein: 1018-1229
Range on HMM: 51-253/284.0
KTEDFIHASYINGYQEARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCdivemeVDTCYQYWPATYDSErhFDFYRIKHHEMNIDNYYTQTILRVldT
|.| ||.|.||| .| . | . | |.|| || . .|| ||.| | | |||| . . . ...| . .. . |. ... .
efsdyinasfitGyqrkdkyiatqGPldntladfWrmiweyncstivllt......kdkcsqywplkivik..eerfkvkvdsveeseeyvvrdiel..s
QAGEEQTIILI-QLPLSNiVSDELSHTERVGILSAIQEIEKIQRK-TGNNPILVHCSDTVSRSGVFCVLYTSIQQMKIEQQVNIYEILYNMRTCKPGLIT
. |.|. | | | . | . .. .. ......| ....|.|||| | |.||. || . ...|| |.||..|... ..| .. |.
edgkekdirkirqfhflg.wpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrtgvyivldvlldrmkeekqvdvynfvrdlrqqrntlvq
TPVQYKMVYLLLMR
||||..| |.
dlvqykfiysalle
|
|||||||||
0051429 | (Phosphotyrosine protein) phosphatases II | 1019-1234 | 3e-32 | 107.7 | In-house | 3-228 (272) | alignment | ||
Range on Protein: 1019-1234
Range on HMM: 3-228/272.0
TEDFIHASYINGYqeaRS------FIVAESPTKLTAANFWSMiVKNKCSVIVMLCDIVEMEVDTCYQYWP----------ATYDSERHFDFYRIKHHEMN
... |.|....|| . .. . |..||||.|| . ......||.|.. .|.. . |..||| ... . . ..|......
lsgyiNardvggy...grvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllsee
IDNYYTQTILRVLDTQAGEEQtIILIQLPLSNIVSDELSHTErvgILSAIQEIEKiqrktgNNPILVHCSDTVSRSGVFCVLYTSIQQMKIEQQVN----
. ..|. . |.. . .| . .| ... . . . .|...... . ..|.||||| ..|.|....|. ..... |. |.
llldyilrellltlllsagea.revmhlhytdwpdhgvpqea...llellellld......ggpvlvHCsaGkdRTGtvvallllllgvsletivddYll
----IYEILYNMRTCKPGLITTPVQYKMVYLLLMRYVEEF
..|.. .| . || . |. ||...| |. .....
tnlyleeaveelraqrpgavqteeqylflyeallellrsl
|
|||||||||
subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 1017-1229 | 5e-32 | 106.5 | In-house | 86-289 (319) | alignment | ||
Range on Protein: 1017-1229
Range on HMM: 86-289/319.0
KKTEDFIHASYINGYQEARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCdivemeVDTCYQYWPATYDSErhFDFYRIKHHEMNIDNYYTQTILRVld
. |.| ||...||| .| | | . | |.|| || . .|| ||.| | | |||| . . . . .| . .. . |. ...
eefsdyinasfvtGyqrkdkyiaaqGPldntladfWrmiweyncstivllt......kdkcsqywplkivik..eerfkvkvdsveetaeyvvrdiel..
TQAGEEQTIILI-QLPLSNiVSDELSHTERVGILSAIQEIEKIQRK-TGNNPILVHCSDTVSRSGVFCVLYTSIQQMKIEQQVNIYEILYNMRTCKPGLI
.. |.|. | | | . | . .. .. ......| ....|.|||| | |.||. || . ...|| |.||..|... ..| .. |.
sedgkekdirkitqfhflG.wpdvGvpdypsdlmrlvkkvrhltskenhranivvhcsaGvGrtGvyivldvlldrmkeekqvdvynfvrdlrqqrntlv
TTPVQYKMVYLLLMR
||||..| |.
qdlvqykfiysalle
|
|||||||||
subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 728-943 | 7.3e-32 | 105.5 | In-house | 59-274 (285) | alignment | ||
Range on Protein: 728-943
Range on HMM: 59-274/285.0
HSYINASYIDG-YKKKHQFIATQGPLPQTLVDFWRLIWQEDICCILMMLsITSDGGIVRCQQYWPDAIGVAAFYGPFKIIVEGINDNKVSEERIIKLSMT
. || ||.. | . .|.||||||.|| |||..|.|| |. .||. .||. .| |.|. .| .| ..| . ... .. . |...
rdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlc.tlfeggvekcalyypeklgevvkfgkyeitlteckeeaiagtilnaltvi
SSSSSDNSHKTIHHYLFKCWPDHGVPATPTSTHSFYEQIKMWLDLPPPVLIHCSGGIGVTGMLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEE
. . . . | |||. | .|. .| |. .||| |.| | .. | . . .... || .||. |.. .|.
ntedasseplymnhvqvpwwpdqlapedarpmielykwvkkvnpkekpicvhcsagvgrtatfvgidyatirimenpniemldivremramrfqavqshm
QYQFVHYVLLEAFYTIG
|. |.. ||.| | |
qflflyvvlmeyfigeg
|
|||||||||
subfamily_ptpA1_pd | Subfamily ptpA1 | 674-894 | 1.2e-31 | 104.9 | In-house | 23-251 (418) | alignment | ||
Range on Protein: 674-894
Range on HMM: 23-251/418.0
FKSEFQRLQNFGHLFSTEVANCSENKKRNRFKTILPYDNNLLTLRPISSRGdcSHSYINASYIDGYKKKhQFIATQGPLPQTLVDFWRLIWqEDICCILM
| ||. |.. | . | .||. ||| . . |. | . |||| |||| | |||.||||||.|. ||||..| |. | |..
ikeefrlleesvgpsetsegdkkhntsknrytnilpvnhtrvqlkkiqdke..gsdyinanyidgaypk.qfictqgplpntiadfwrmvw.enrcriiv
MLSITSDGGIVRCQQYWPDAIGVAAF--YGPFKII-----VEGINDNKVSEERIIKLSMTSSssSDNSHKTIHHYLFKCWPDHGVPATPTS----THSF-
||| |. ..|..|||. || | || . . || .. . | || . . . . | .| .. |||| .| ||
mlsresencrikcdrywpeqiggeqfsiygngnevfgtysvelveviqdpereiitrnirlt..fegetrditqyqyegwpdhnipdhtqpfrqllhsit
--YEQIKMWLDLPPPVLIHCSGGIGVTGMLISIMI
.|| | |...||| |.| || . . .|
nrqnqiipssdrnvpiivhcsagvgrtgtfctavi
|
|||||||||
subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 1006-1231 | 2.6e-31 | 103.5 | In-house | 48-277 (287) | alignment | ||
Range on Protein: 1006-1231
Range on HMM: 48-277/287.0
LPPDEYRVVLNKKTE---DFIHASYINGYQEARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPATyDSERHFDFYRIKHHEMN
|| |. ||.| ...| |.| | |. .|.. .||.| .| | .|| ...... ...... || ||.||| . | . . .
lPiddtrvllsaegelGsdyinanyvasytddeafiaaqgPiaatvrdfwravletrsasvitmtreveearlkcykywPer.evPmrvGGysvvlldyd
-IDNYYTQTILRVLDTQAGEEQtiILIQLPLSNIVSDELSHTeRVG----ILSAIQEIEKIQRKTGNNPILVHCSDTVSRSGVFCVLYTSIQQMKIEQQV
. |. ||..| .. | . .. || | .. .. |. | || .|. | || . .. |..||.. . |||.. ... ..... .|
ikePeygvralrlidletrear..vvkqldllswPdkvlaPt.avglirfvldvkqhielardasevGPlvvhddvGiGrsGillatlvlvsrledlGrv
NIYEILYNMRTCKPGLITTPVQYKMVYLLLMRYV
.. .. .| . .|. ..||....| |. |
dvaavvirlreyraalvqavvqlrllyealvtyy
|
|||||||||
subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 697-944 | 2.9e-31 | 103.2 | In-house | 54-294 (305) | alignment | ||
Range on Protein: 697-944
Range on HMM: 54-294/305.0
ENKKRNRFKTILPYDNNLLTLRPISsrgdcSHSYINASYIDGY-KKKHQFIATQGPLPQTLVDFWRLIWQEDICCILmMLSITSDGGIVRCQQYWPDAIG
.. .||.. . |.... | | || | |. ...||..|||| ||. .|| .. |. . |. || | . | ..| |||| | |
iaitknryqdvpcqdqsavkldkps.....psdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkveqiv.mlcktvelgklkcaqywpaaqg
VAAFYGpFKIIVEGINDNKVSE-ERIIKLSMTSSSSSDNSHKTIHHYLFKCWPDHGVPATPTSTHSFYEQIKmwlDLPPPVLIHCSGGIGVTGMLISIMI
|.|| . .| | . |.... . | . . .. | . ||| ||| .. . |. |...||| ||| || ...|
eklelk.sgivvenvsgskpmerdaeiqitllnltysgdqkmsvrhlqwtewpdrgvppckltslellsair...gskvpivvhcsagigrtgtivaiey
GIEQGLSTGGVDVM-AIVNKMRSQRMNMIQTEEQYQFVHYVLLEAFYTIGK
.|. . | .|. .| || ||.. || |.| |.|. | |
ilekiaenkpcppmpelvkalrdqrafsiqndvqylfihrvmlnyflekyk
|
|||||||||
subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 1005-1228 | 7e-31 | 102.3 | In-house | 58-276 (315) | alignment | ||
Range on Protein: 1005-1228
Range on HMM: 58-276/315.0
YLPPDEYRVVL----NKKTEDFIHASYINGYQEARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPATydsERHFDFYRIKHHE
.. |. || | |.. |.. |..|.||. | .| |..| . .|| .. ..... |||| ..|| | . .||| . . . . . .
iiaydksrvqlpllendphsdyvnanfidGynkkrryiaaqgpnvasvkdfwrlvfeedigkivmltnlvegekrkaekywpdk...kviyGkitvtrks
mniDNYYTQTILRVLDTQAGEEqTIILIQLPLSNIVSDELSHtERVGILSAIQEIEKIQRKTGnNPILVHCSDTVSRSGVFCVLYTSIQQMKIEQQVNIY
....|. | | . |.. ..|| .. .... . .. |. . . . .. .|.||||. | |.| |. | . ..|...|. ...|
...eevnteytvrtlsvvfgdn.irevvqlhytswpdmgvpk.ytiplmnlirtvkqhhtnsv.gaivvhcsaGvGrtGtfitldavldqaeaenaidvy
EILYNMRTCKPGLITTPVQYKMVYLLLM
... ..| . ... . ||...| |.
nfitgvrqnrikmvqvaeqyqfiydall
|
|||||||||
subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 670-938 | 1.2e-30 | 101.6 | In-house | 17-270 (288) | alignment | ||
Range on Protein: 670-938
Range on HMM: 17-270/288.0
GGKGFKSEFQRLQNFGHLFSteVANCSENKKRNRFKTILPYDNNLLTLRpissrgDCSHSYINASYIDGYKKKHQFIATQGPLPQTLVDFWRLIWQEDIC
. .| | |.. | . . . . .| |.|.. . | . | | .. ||.| . | |...| .| || |. .|... ..|.
aveglkkeyrdspneasidi..idsfianptrdryenlprcditrvkls......ddpdfyiaanvvssakykrrlicaqaPlngtieelWkmllesdve
CILMMLSITSdGGIVRCQQYWPDAIGVAAFYGPFkiiVEGINDNKVSEERIIKLSMTSSSSSDNSHKTIHHYLFKCWPDHGVPATPTSTHSFYEQIkmwL
|.|. . | . ..|.| .| .| .| . . .... ....|.|. | . .. . . .. |.|.||| | . | .
yivmlcelle.kGkeksaeyfPsklGekarigrl...ctvvkkkradidklvkvsllriskegeekvivkilhlleWdddgvPenylsplrllevl...k
DLPPPVLIHCSGGIGVTGMLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEA
.| |...|.| |.| || || |.| .|. .. . . ...|.| .|.. |||| || .|| ..||
slqkPivvhssaGvGrtgtlililialeslrlddflgirsllaklreerfkaiqtemqylyvhrcvlee
|
|||||||||
subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 1001-1229 | 3.4e-30 | 99.6 | In-house | 48-274 (515) | alignment | ||
Range on Protein: 1001-1229
Range on HMM: 48-274/515.0
RSDLYLPPDEYRVVL----NKKTEDFIHASYINGYQEARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPATYDSERHFDFYRI
| || | || | .. .|.. ||||.... ...| . | | . .||....... . |.|. . | . | .||| .| ...
ryknilPydsvrvklevindnPhsdyfnasyipsfdndkayiasqgPnkasvddfWrlvlqenvttiamvtklkegdkikcgkyWPdkpgdsvkfGsikv
KHHEMNIDnyyTQTILRVLDTQAGEEqTIILIQLPLSNIvSDELSHTERVGILSAIQEIEKIQRKTGnNPILVHCSDTVSRSGVFCVLYTSIQQMKIEQQ
. .. . |..| | | |.. . . | . . |. . . .| |.|. . . |...||| | | ||.. . . ..| .
elvsleac...tggikrkltvlkgdd.srtvtqfhfteW.PdkGvpkhtssllklikevkadhgqyt.hpliihcsaGvGrtGvvisidsvvahakttrm
VNIYEILYNMRTCKPGLITTPVQYKMVYLLLMR
|...... |.| .| |. | || ..| ..
vdvfnfvtnirqkrpylvqtqeqyafiygavle
|
|||||||||
0036282 | (Phosphotyrosine protein) phosphatases II | 1020-1224 | 3.6e-30 | 100.3 | In-house | 2-163 (174) | alignment | ||
Range on Protein: 1020-1224
Range on HMM: 2-163/174.0
EDFIHASYINGYQEARSFIVAESPTKltaanFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPAtydserhfdfyrikhhemnidnyytqtilrvldtqA
.|.|.||..... . .|. |.. || |. .......|||.. .|.. |..|||
sdyinaspldlsyitprliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe...................................l
GEEQTIILIQLPLSNIVSDELSHTERvgILSAIQEIEKIQRKTGNNPILVHCSDTVSRSGVFCVLYTSIQQMKiEQQVNIYEILYNMRTCKPGLITTPVQ
| . ||. ... .. .. .|......|... . ...|.||||| |.|.|.....| ..... | |....... .|...|| ..|| |
redlerlgiqylylpwpDhgvpdlsi..llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtpsQ
YKMVY
|. .|
yrfly
|
|||||||||
subfamily_PTPN14_pd | Subfamily PTPN14 | 1005-1232 | 6e-30 | 99.3 | In-house | 58-297 (300) | alignment | ||
Range on Protein: 1005-1232
Range on HMM: 58-297/300.0
YLPPDEYRVVLNK---KTEDFIHASYINGY--QEARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPATYDSERH--FDFYRIK
|| .. || |. .....| || |. . ||.||| .| .|| .|| |. .. ..|||| .. | . ...|.| . ..... |. ...
vlPyednrvelsptkenstgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivmlteeeedgkeksfkyfPkleskkktvefgkfkvt
HHEMNIDNYYTQTILRVLDTQAGEEQTIILIQL---PLSNIVSDELSHTERVGILSAIQEI--EKIQRKTGNNPILVHCSDTVSRSGVFCVLYTSIQQMK
. . . .. | |.. ..||.|.. .| | .. .| . . . . .... .... | . |.|||||. | |.|| . |. ..
tkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseveskeskPPvlvhCsaGvGrtGvlilsdlliatle
IEQQVNIYEILYNMRTCKPGLITTPVQYKMVYLLLMRYVE
.....| ..| .|. . |. | |||.|| .|..|..
hneeidikkvlarLreqrmllvqtlaqYkfvYkvlikylk
|
|||||||||
0051082 | (Phosphotyrosine protein) phosphatases II | 729-936 | 7.6e-30 | 98.9 | In-house | 4-150 (151) | alignment | ||
Range on Protein: 729-936
Range on HMM: 4-150/151.0
SYINASYIDGYkkkhqFIATQGPLPqtlvDFWRLIWQEDICCILMMLSITSDGgivRCQQYWPDAIgvaafygpfkiivegindnkvseeriiklsmtss
.|||.||..|. .....|||. ||..|.....| .|... | . | | .|.|..
dyinfsyvtgg.....lyrsggpla....dflellkelgiktivnlrseeerg...ycpeylpelg..................................
sssdnshKTIHHYLFKCWPDHGvpaTPTSTHSFYEQIKMWLDL-PPPVLIHCSGGIGVTGMLISIMIGIeQGlstggVDVMAIVNKMRSQRMNMIQTEEQ
...|. . |||.| .|.|.... | ... || . |||.|||.|.| ||.|. ... . .| |.. .... .|..|....|...|
.......ievlhipildwpdpg...lplsfdavleflellldkkngpvlvHCsaGkgRTGtlvalylml.lg.....vsleealeeyrlkrpgvvqpnqq
YQFVHYVLL
..|....||
flfqlfall
|
|||||||||
0041856 | (Phosphotyrosine protein) phosphatases II | 1007-1230 | 8.3e-30 | 99.1 | In-house | 12-170 (182) | alignment | ||
Range on Protein: 1007-1230
Range on HMM: 12-170/182.0
PPDEYRvvlnkkTEDFIHASYINGYQEARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCdivemevdtCYQYWPatydserhfdfyrikhhemnidny
|.| | |.|.|... |.. |. ||.. |.. | |.|. |. ......||.|. ...|||
pydhsr......dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt.........eelywp........................
ytqtilrvldtqagE---EQTIILIQLPLSNIVSDElshtervgILSAIQEIEKIQRktGNNPILVHCSDTVSRSGVFCVLYTSIQQmkieqQVNIYEIL
| . | ...|| . . .... ||.... ..|.||||| |.|.|.....| ... .|...|..
..............ellerlgiqylylpwpDhgvpd........ldelldfieevle..eggpvlVHCsaGvgRtgtlvaaylmkkl.....gvsleeav
YNMRTCKPGLITTPVQYKMVYLLLMRY
.| ..|| ..|| || ...|.|. .
klvrsrRpgmvitpnqyfflqlallel
|
|||||||||
0044763 | (Phosphotyrosine protein) phosphatases II | 721-936 | 1.5e-29 | 98.3 | In-house | 11-168 (178) | alignment | ||
Range on Protein: 721-936
Range on HMM: 11-168/178.0
SSRGDCSHSYINASYIDGYkkkhQFIATQGPlpqtlVDFWRLIWQEDICCILMMLSITSDGgIVRCQQYWPDAIGvaafygpfkiivegindnkvseeri
. .| .. |||||.|... ......| .|...|.....| .|... . . | . | .|||. |
nleglersdyinaseilpg....lylgslpp.....addlellkelgithivnlteelelg.flkcdpywpeeag.........................
iklsmtsssssdnshktiHHYLFKCWPDHGVPATPTSTHSFYEQIKMWL-DLPPPVLIHCSGGIGVTGMLISIMIGIEQglstgGVDVMAIVNKMRSQRM
.||. .|||||| . .. |.| |. .| . . |||.||| |.| .|.|. . . ... |... .... .|..|.
..................iqylhipipDhgvpdllehflefvefieealdekggpvlVHCsaGvgRsgtlvaaylmkkl.....glsleeaielvrerRp
nMIQTEEQYQFVHYVLL
......|....... |
.ivpnpgqlrqLyefel
|
|||||||||
subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 674-937 | 4.3e-29 | 96.1 | In-house | 13-267 (281) | alignment | ||
Range on Protein: 674-937
Range on HMM: 13-267/281.0
FKSEFQRLQNFGHLFSTEVANCSENKKRNRFKTILPYDNNLLTLRpISSRGDCSHSYINASYIDGYKKKHQFIATQGPLPQTLVDFWRLIWQEDICCILM
|| || | | | |.|.||. | | . |. . | || | || |. .| |||| .| ||||.||||. .|.|
fkqefsnlpgdppsdlctvfnqpvnnkknrylnipcldisrvqlk.vkmpnknstdyihanyirspflkrgyiltqgpkketradfwrmiwqenttaivm
MLSITsDGGIVRCQQYWPDAIGVAAFYGPFKIIVEGINDNKVSEERIIKLsmtsssSSDNSHKTIHHYLFKCWPDHGVPATPTSTHSFYEQIKMWldLPP
. .. . .| .|.| .. . . . | || ..| | . . | |.|.| ||| || . .|. |
lcqfl.etnrekcaeyfprnahcclqfdklsvsyedstvnkslvttrlnl......syegetrlithwlwkewpdwqvpessevmlkilrkirar..stp
PVlIHCSGGIGVTGMLISIMIGIEQGLSTG-GVDVMAIVNKMRS-QRMNMIQTEEQYQFVHYVLLE
|| |||| |.| .| |... | .. | |. || ..| | .|| .|| .. |||.
pv.ihcsagvgrsgtlmaveialqsihshftlpdikqivshlrvtgraasvqtlqqymliwkvlld
|
|||||||||
subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 696-937 | 1.9e-28 | 93.9 | In-house | 50-288 (310) | alignment | ||
Range on Protein: 696-937
Range on HMM: 50-288/310.0
SENKKRNRFKTILPYDNNLLTLRPISSRgdcSHSYINASYIDGYKKKHQFIATQGPLPQTLVDFWRLIWQEDICCILMMLSItSDGGIVRCQQYWPdAIG
.. ..||. .. |. . |. || . || | |. . || .|||| .|..||||.|.|| ||.. . .. | .| ||| ..|
kkymhknrysdvvcldtsrvklkidksr...yedyihanyvktnylrstficsqgplqhtiidfwrmifqeraesilllckv.geegrpkcvgywp.slg
VAAFYGPFKIIVEGinDnKVSEERIIKLSMTSSS---SSDNS---HKTIHHYLFK--CWPDHGVPATptSTHSFYEQIKMWLDLpPPVLIHCSGGIGVTG
|. || .. . . | | .|..| |. | . | | ||| ||| |. ... . |...||| |.. ..
vtetygcirvtnls..e.sseefeicnlavtfvpdnvpvdeqpanlkelrvslikwpnwpdrgvpde..kchtvpqrllaqvrh.gpcvvhcsagkdrly
MLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLE
..... . |.. ||. .. ... .|. |||| || ....| .
vvvalklkidkldrglkvdaeevktellksraiciqtelqyliidrvrii
|
|||||||||
subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 728-945 | 2.6e-28 | 93.7 | In-house | 75-284 (301) | alignment | ||
Range on Protein: 728-945
Range on HMM: 75-284/301.0
HSYINASYIDGYKKKHQFIATQGPLPQTLVDFWRLIWQEDICCILMmLSITSDGGIVRCQQYWPDAIGVAAFYGPFKIIVEgiNDNKVSEERIIKLSMTS
| | .|. . |.||||||||..| ||| .. | |. | | |. . . . .|..| | |. | ||| .. | ... ...|.| ..
rvPihanwiptsGhphrfiatqgPlkntsedfwamlvqydvekivm.lgqkvekleekceeylpvkisekldigrfkikik..nkelilnkkiskrtlev
SSS-SDNSHKTIHHYLFKCWPDHGVPATPTSThsfYEQIKMWLDLPPPVLIHCSGGIGVTGMLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEE
| . . .|. || .. |.|.||| . . . .. ... . |...||| ||| . .|. . . .. ... ....| .| | .||..
edstgkfatrtvthyqysewtdrgvPkshael...fdlmelvkksekPivvhcsaGiGrsvafigteylareveadptieltealkhlrehrwngvqtns
QyqfVHYVLLEAFYTIGKE
| .... | . | . ||
q...lywmtlGtvyrlike
|
|||||||||
subfamily_PTPN13_pd | Subfamily PTPN13 | 1006-1228 | 8.6e-28 | 92.4 | In-house | 47-266 (273) | alignment | ||
Range on Protein: 1006-1228
Range on HMM: 47-266/273.0
LPPDEYRVVLNKKTEdFIHASYINGY--QEARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPATYDSERHFDF-YRIKHHEMN
|| || || |.... .| ||.|. .. ..|.. | |...|| |. |..||.|. .| . | .||| . ... .... ...
lPydetrvklgdegg.yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvkchrywPesknkklkvsnrlevellkvq
IDNYYTQTILRVLDTQAGEEQTIILIQLplSNiVSDELSHTERVGILSAIQEIEKIQRktGNNPILVHCSDTVSRSGVFCVLYTSIQQMKIEQQVNIYEI
. ... | | |...|| . . ... . | .. . .| ..|. ..|. . ||.|||| . |||.. .... .. .. ...... ||
kldgfvvralavkdsesgesrevahlnf..vk.wPdhgvPssaaellqfvaevrrlqt..dagPivvhcsaGiGrsGtlitidvvlglierdkefdvkei
LYNMRTCKPGLITTPVQYKMVYLLLM
. ..| . |.. | || .|| ..
vrklreqrqgvvqtkdqyifvykail
|
|||||||||
subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 1009-1234 | 9e-28 | 91.7 | In-house | 69-286 (290) | alignment | ||
Range on Protein: 1009-1234
Range on HMM: 69-286/290.0
DEYRVVLNKK-TEDFIHASYINGYQEarSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPATYDSERHFDFYRIKH-HEMNIDNY
| ||.|. |..|| |..| . ||... ..| |. ..| |....| ..|||||...| | ||.| . | . . | . |.
dktrvilkdGydGdyvhanyvkGlka..mfiltqGalkdtvidiwrmvlqekvaaivmlceliedGkakceqyypekeGevltfGeitvlcseeddkdan
YTQTILRVLDTQAGEEQTIILIQlpLSNiVSDELSHTERVGILSAIQEIEKIqrktgNNPILVHCSDTVSRSGVFCVLYTSIQQMKIEQQVNIYEILYNM
. .| | | ..| | . .. . | . .| .. . |. . |. |||| . |.| | . ...| . ..... .. .
iikktlsvrdkdsGkehklkhlk..iks.wpdksvalstlallrtlrilrka.....sGpvvvhcsaGiGrtGtfvaievglqilldGkeldlldlvral
RTCKPGLITTPVQYKMVYLLLMRYVEEF
| .. . . .|| .. .|. . .|
rnsrlnsvqvdiqylalveilldlGkdf
|
|||||||||
subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 1009-1224 | 2.7e-27 | 90.5 | In-house | 16-232 (237) | alignment | ||
Range on Protein: 1009-1224
Range on HMM: 16-232/237.0
DEYRVVLNKK--TEDFIHASYINGYQE-ARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPATyDSERHFDFYRIKHHEM-NID
| ||||. . |.| |.|..|.. ...| |. | . . .|| |. ..|||||||| ..| . |..||| | | . . . . . ..
dhsrvvlkgagsgsdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpst.dqpaaygvltvslkkkeefs
NYYTQTILrvlDTQAGEEQTIILIQLPLSNIVSDELSHTERVGILSAIQEIEKIQRK-TGNNPILVHCSDTVSRSGVFCVLYTSIQQMKIEQQVNIYEIL
.| ...| .. .. . . ||. | . .| ..| . .. . | ..||| | |.|.| |. . ..| | .. |.||. .
dytvrsll...lskrltlkevrlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlrqakekkvvdiynyv
YNMRTCKPGLITTPVQYKMVY
|.. .| .| | || ...
ysieedrpyiiqtkdqyvfih
|
|||||||||
PTPc_DSPc_SM00012 | 837-937 | 2.1e-26 | 87.5 | In-house | 1-105 (105) | alignment | |||
Range on Protein: 837-937
Range on HMM: 1-105/105.0
TIHHYLFKCWPDHGVPATPTSTHSFYEQIKMWLDLP---PPVLIHCSGGIGVTGMLISIMIGIEQGLST-GGVDVMAIVNKMRSQRMNMIQTEEQYQFVH
|..|| .. ||||||| ...| .. ...| . .||..||| |.| ||... . | ..| .. . ||. ||...|.||..|.||||||.|..
tvkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylfly
YVLLE
.|||
ralle
|
|||||||||
subfamily_PTPRN_pd | Subfamily PTPRN | 963-1231 | 3e-26 | 86.8 | In-house | 23-292 (297) | alignment | ||
Range on Protein: 963-1231
Range on HMM: 23-292/297.0
DEILNMNRYEAHYKALQVLTVKPNSVLRNFGLSNLPLVRSDLYLPPDEYRVVLNKKT----EDFIHASYINGYQ-EARSFIVAESPTKLTAANFWSMIVK
| . | .| |....|| .|.. |. || || |. || |.... .|.| || | . | ..| ...| | |.|| |. .
dhlknkdrlekewealcayeaepstkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplastvadfwqmvwe
NKCSVIVMLCDIVEMEVDTCYQYWPATYDSERHFDFYRIKHHEMNIDNYYTQTI-LRVLDTQagEEQTIilIQLPLSNIVsDELSHTERVGILSAIQEIE
. . |||.|. . | .| |..||| . . |. .. . |.| ... |. |.|. | .|. |. .| .. .| . ..
qGvvvivnltrleeegvkqckrywpdeGsevyhiyevhlvsehiwcddylvrsfylknlqts..etrtv..tqfhflswp.eegvPasaksllefrrkvn
KIQRKtGNNPILVHCSDTVSRSGVFCVLYTSIQQM-KIEQQVNIYEILYNMRTCKPGLITTPVQYKMVYLLLMRYV
| | ||.||||| . |.||.... .... | ....| | .| .|||. | |..... . . |
ksyrG.rscpivvhcsdGaGrtGvyilidlvlnrllkGvkeidiaatlehlrdqrpglvktkdqfefaltavaeev
|
|||||||||
0049772 | (Phosphotyrosine protein) phosphatases II | 1003-1233 | 6.6e-26 | 87.2 | In-house | 53-282 (314) | alignment | ||
Range on Protein: 1003-1233
Range on HMM: 53-282/314.0
DLYLPPDeYRVVLNK---KTEDFIHASYINGYqeaRSFIVAESPTKLTAANF----------WSMIV--KNKCSVIVM---------------------L
|| | ||.|.. .. |.|.|||..|. ..||... |.. | .| |.|.. .... .||| |
ldilpad.nrvilpglpvsgsdyinasyvdgf...lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivmsrdevladelsrLdaAlgKtpl
CDIVEMEvdtcyqywpaTYDSERHFDFYRikhHEMNIDNYYTQTILRVLDTQAGEEQTIILIQlplsnivsdelshtervgILSAIQEIEKIqrkTGNNP
... . . ......... |.. ...........|.. ... .| . ...... ||. ..|
lildgng..........neptaadlellk...eelydpelferlgikylripvpDgsaplled..................fdeflefieea...dkggp
ILVHCSDTVSRSGVFCVLYTSIQQMkieqQVNIYEILYNMRTCKP-----GLITTPVQYKMVYLLLMRYVEE
.||||.. ..|.|.|.|.. . .. .|.. |.| .| . | |.| .. || ... |. |..
vlvHCkaGkgRtgtfvvaaylmkll....gvsleealedvrlkRpinpnpgfieqleqyefilealleylkf
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 696-861 | 3.1e-25 | 83.6 | In-house | 31-189 (297) | alignment | ||
Range on Protein: 696-861
Range on HMM: 31-189/297.0
SENKKRNRFKTILPYDNNLLTLRpissRGDCSHSYINASYIDGYKKKH--QFIATQGPLPQTLVDFWRLIWQEDICCILMMLSITsDGGIVRCQQYWPDA
. ..||.. || .|.. . |. |. . |||| |. .... ..| .|||| .|. |||.|....|. | |. . ..| .| |||..
nsslrknryrdilatddtrvkll....rviterdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklq.edGrdkcapywpsv
IGVAAFYGpfKIIVEGINDNKVSEERIIKLSMTSSSSsdNSHKTIHHYLFKCWPDHGVPATPTSTHSF
. | ...|| . . .|.| .. . .. ..| | |||||||. |
vqerlkag..dvvveflsstsdefdrviltelqliyr..sesrvvrhvqflswpdhGvpsdledlvrf
|
|||||||||
0043147 | (Phosphotyrosine protein) phosphatases II | 1018-1224 | 3.5e-25 | 84.1 | In-house | 3-154 (172) | alignment | ||
Range on Protein: 1018-1224
Range on HMM: 3-154/172.0
KTEDFIHASYINGYQEARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIvemevdtcyqywpatydserhfdfyrikhhemnidnyytqtilrvldt
. .|.|.|||...| ..||. |. | | || |. ......||.|..
egsdyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltel................................................
qageeqtiI---------LIQLPLSnIVSDELSHtERVGILSAIQEIEKIQRKTGNNPILVHCSDTVSRSGVFCVLYTSIqqmkieQQVNIYEILYNMRT
||. . | .|.... |.... . ..|.||||| |.|.|.....| . ......|.. .|.
........lydpellerlgiqylyl.pwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml......lglsleeavalvre
CKPGLITTPVQYKMVY
..|| ...| ||. .|
kRpgavqnpsqyrfly
|
|||||||||
0046846 | (Phosphotyrosine protein) phosphatases II | 1020-1231 | 5.8e-25 | 83.5 | In-house | 12-173 (176) | alignment | ||
Range on Protein: 1020-1231
Range on HMM: 12-173/176.0
EDFIHASYINGYQearsFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPATYDSERhfdfyrikhhemnidnyytqtilrvldtqa
|.|.|..| |. .|. |. | |.|. |. .......|.|.. ||.. |..||| .. .
ldyinanlilgsr....piatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgi..............................
geeqtiiliqlPLSN-IVSDELSHTErVGILSAIQEIEKIQRKTgnNPILVHCSDTVSRSGVFCVLYtsiqQMKIEQQVNIYEILYNMRTCKP-GLITTP
. . | . .|.....|.. ... .|.||||| ..|.|.....| .. |......|.|. .| ..| | ..||
...........qylhlpwpDhgvpdl.elllellefirealkeg..gpvlVHCsaGigRtgtlvaay....llelekglsveealalvreqRplgavqtp
VQYKMVYLLLMRYV
||...| ....
eQyrflyefellll
|
|||||||||
0049260 | (Phosphotyrosine protein) phosphatases II | 1027-1224 | 2e-24 | 81.5 | In-house | 1-143 (152) | alignment | ||
Range on Protein: 1027-1224
Range on HMM: 1-143/152.0
YINGYQEARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWpatydserhfdfyrikhhemnidnyytqtilrvldtqageeqtii
.|.|| . || .. |. |.|.|| |. ......||||.. .|. . |.||.
fidgyampfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi.............................................
liqLPLSNIVSDELSHTERVGILSAIQEIEKIqRKTGNNPILVHCSDTVSRSGVFCVLYTSIqqmkieQQVNIYEILYNMRTCKPGLITTPVQYKMVY
| . | . .| ... |||. .. ..|.||||| |.|.|.....| . ..|...|.. .|...|| ...| |.. .|
...qylhlpwpDhgvpdlsqlllflllfiekl.aldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpgqlrfly
|
|||||||||
subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 1020-1227 | 3.8e-24 | 79.9 | In-house | 76-275 (439) | alignment | ||
Range on Protein: 1020-1227
Range on HMM: 76-275/439.0
EDFIHASYINGYQEARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEmevdtCYQYWPATYDSErHFDFYRIKHHEMNIDNYYTQtILRVLDTQA
.| | ||.|| . . .| .. |.| |. .|| .....|.. ||||...|| |.|||. . . | ..... || . ..|.. .
shyinanyikGyyddklyiatqgpkkettddfwrlviekktvtivmltnlve.....sykywpsdaevc.ygdiavrvdrnielpnyvir.gfkvfnerd
GEEQTIILIQLPLSNIvSDELSHTERVGILSAIQEIEKIQRKTGNNPILVHCSDTVSRSGVFCVLYTSIQQMKIEQQVNIYEILYNMRTCKPGLITTPVQ
|. ..|. |. .. .| .. |. . | |..|||| | |.| | ...|.|.|..|.| |. .| . .. . .|
ttekertvlqfhyiaw.pdknvpaqashvldflrainsandkeeygpvvvhcsagvGrtGtiialdialeqlklenkvdikgivkvlrkqrkqmvqalcq
YKMVYLLL
| ..| .
yvfiynav
|
|||||||||
0044763 | (Phosphotyrosine protein) phosphatases II | 1009-1230 | 5.4e-24 | 80.2 | In-house | 3-170 (178) | alignment | ||
Range on Protein: 1009-1230
Range on HMM: 3-170/178.0
DEYRVVLNKKT----EDFIHASYINGYqearsFIVAESPTkltaANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPATYDserhfdfyrIKHHEMNID
|..||.|.. |.|.||.| .. .... |. |... .. ......||.|.. .|. |..||| .. |... ..|.
drtrvllsnleglersdyinaseilpg.....lylgslpp....addlellkelgithivnlteelelgflkcdpywpeeag.........iqylhipip
NYYTQTILRVLDTQAGEEQTIIliqlplsnivsdelshtervgilsaiqeiekiqrKTGNNPILVHCSDTVSRSGVFCVLYTSIQQmkieqQVNIYEILY
. ....|. .. .... .. ..|.||||| |.|||.....| ... .....|..
Dhgvpdllehflefvefieeal..................................dekggpvlVHCsaGvgRsgtlvaaylmkkl.....glsleeaie
NMRTCKPgLITTPVQYKMVYLLLMRY
.| ..| ...| |.. .|.. .|.
lvrerRp.ivpnpgqlrqLyefelrl
|
|||||||||
subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 1009-1231 | 2.1e-23 | 77.7 | In-house | 48-270 (285) | alignment | ||
Range on Protein: 1009-1231
Range on HMM: 48-270/285.0
DEYRVVLNKKTEDFIHASYINGY-QEARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPATYDSERHFDFYRIKHHEMNIDnYY
.| ||||... |.||||.. .. ..| .. | | ..|| || ..| . ..||| ..| |. | |.| .| | | | . .
eetrvvlknhdrdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyypeklgevvkfgkyeitlteckee.ai
TQTILRVLDTQAGEEQTIILIQLPL--SNIVSDELSHTERVGILSAIQEIEKIQRKtgNNPILVHCSDTVSRSGVFC-VLYTSIQQMKiEQQVNIYEILY
. ||| | |. . . . |.|. . .. . ..|.. | ..|| |||| | |. | . |..|. |. . .... .|.
agtilnaltvintedasseplymnhvqvpwwpdqlapedarpmielykwvkkvnpk..ekpicvhcsagvgrtatfvgidyatirime.npniemldivr
NMRTCKPGLITTPVQYKMVYLLLMRYV
.||. . . . .|. ..|..|| |.
emramrfqavqshmqflflyvvlmeyf
|
|||||||||
0048076 | (Phosphotyrosine protein) phosphatases II | 819-936 | 2.8e-23 | 77.6 | In-house | 32-140 (145) | alignment | ||
Range on Protein: 819-936
Range on HMM: 32-140/145.0
RIIKLsmtsSSSSDNSHKTIHHYLFKCWPDHGVPATPTSTHSFYEQIKMWLDLPPPVLIHCSGGIGVTGMLISIMIGIEqglstGGVDVMAIVNKMRSQR
... | .| .. ... .||. ||||||| . .|.|.|. .|. . |||.||| |.| ||.|. ... .. ||.. .....||||
tvlnl....tselellerlgiqylylpwpDhgvpdllellleflefieealkeggpvlVHCsaGvgRtgtlvaaylmll.....lgvsleealelvrsqr
MNMIQTEEQYQFVHYVLL
........|..|.....|
pgavpnpgqlrflyefel
|
|||||||||
subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 1009-1226 | 5.4e-23 | 76.4 | In-house | 21-236 (239) | alignment | ||
Range on Protein: 1009-1226
Range on HMM: 21-236/239.0
DEYRVVLNKK----TEDFIHASYINGYQE-ARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPatyDSERHFDFYRIKHHEMNI
| ||||.| |.| |||. |. ...| .. . .. .|| |. ... ||||| ..| |.|||| || .. |. .. ..
dhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywp...dstskycnlrvtlrktev
DNYYtqtILR-VLDTQAGEEQTIILIQLPLSnIVSDELSHTERVGILSAIQEIEKiQRKTGNNPILVHCSDTVSRSGVFCVLYTSIQQMKIEQQVNIYEI
| |.| .. .| |. . . | .. . |. .| ..| | . | | ..||| | |.| | |. . ..| | .. |.|..
fady...iirtfvmsqvgqteeryvyqyhft.vwpdkgvpqyatavlglrrkitk.dslpgarpwvihcsagvgrtgaflvidamlrqakkqktvdifny
LYNMRTCKPGLITTPVQYKMVYLL
. .| .| .. | || ...|
vkairedrphmvqtseqyvfihla
|
|||||||||
subfamily_egg_pd | Subfamily egg | 692-939 | 5.5e-23 | 76.1 | In-house | 34-270 (307) | alignment | ||
Range on Protein: 692-939
Range on HMM: 34-270/307.0
VANCSENKKRNRFKTILPYDNNLLTLrpISSRGDCSHSYINASYIDGYKKKHQFIATQGPLPQTLVDFWRLIWQEDICCILMMLSITSDggiVRCQQYWP
| ..|... | | . | ..| || . .| | ...| .|| .| || | ||||...||.. |.|. | ||. |||
taasdnnlekarskrvhckdssrvkl..elrrGqylddfihanrvkGkpllnefilaqaplkntvddfwrmvfqeevqyivmltsrkes...erceyywp
DAIGVAAFY--GPFKIIVEGINDNKVSEERIIKLSMtssSSSDNSHKTIHHYLFKcWpdhgvpATPTSTHSFYEQIKMWLDLPPPVLIHCSGGIGVTGML
| .. . | ..| ..... |. || . .|. . . |. . . .| .. ... .| ||.... |. .. |
kaesdslvtvpGslrienlkvdskadplfrvtklkl...vGgddeerflehwqgd.v......nnssdvysplrvlrklrnlskpvvvqdilGvskaatl
ISIMIGIEQGL--STGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEAF
..| | . . | . |. | .| .| ... .| ||. ..| |
vaieiallsllrGpitkslvlravvflrlrrrlsvesvllylfvyrlvlfff
|
|||||||||
subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 1009-1227 | 5.6e-23 | 76.3 | In-house | 20-236 (239) | alignment | ||
Range on Protein: 1009-1227
Range on HMM: 20-236/239.0
DEYRVVLNKK----TEDFIHASYINGYQE-ARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPatyDSERHFDFYRIKHHEMNI
| ||||.| |.| |||. |. ...| .. . .. .|| |. ... ||||| ..| |.|||| || .. |. .. ..
dhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywp...dstskycnlrvtlrktev
DNYYtqtILR-VLDTQAGEEQTIILIQLPLSnIVSDELSHTERVGILSAIQEIEKiQRKTGNNPILVHCSDTVSRSGVFCVLYTSIQQMKIEQQVNIYEI
| |.| .. .| |. . . | .. . |. .| ..| | . | | ..||| | |.| | |. . ..| | .. |.|..
fady...iirtfvmsqvgqteeryvyqyhft.vwpdkgvpqyatavlglrrkitk.dslpgarpwvihcsagvgrtgaflvidamlrqakkqktvdifny
LYNMRTCKPGLITTPVQYKMVYLLL
. .| .| .. | || ...| .
vkairedrphmvqtseqyvfihlav
|
|||||||||
0051082 | (Phosphotyrosine protein) phosphatases II | 1020-1226 | 5.8e-23 | 76.6 | In-house | 3-148 (151) | alignment | ||
Range on Protein: 1020-1226
Range on HMM: 3-148/151.0
EDFIHASYINGYqearsFIVAESPTKltaaNFWSMIVKNKCSVIVMLCDIVEMEvdTCYQYWPATYdserhfdfyrIKHHEMNIDNYYTQTilrvldtqa
.|.|..||. |. ... |. |. .. ......||.|.. .|.. .|..|.|.. |... . |.. ...
sdyinfsyvtgg.....lyrsggpla....dflellkelgiktivnlrseeerg..ycpeylpelg..........ievlhipildwpdpg.........
geeqtiiliqlplsnivsdelshteRVGILSAIQEIEKIQRKTGNNPILVHCSDTVSRSGVFCVLYTSIQQmkieqqVNIYEILYNMRTCKPGLITTPVQ
.. |..|. .. ....|.|.||||| ..|.|....|| ... |...|.| .| . ||..... |
.........................lplsfdavleflellldkkngpvlvHCsaGkgRTGtlvalylmllg......vsleealeeyrlkrpgvvqpnqq
YKMVYLL
. ....
flfqlfa
|
|||||||||
subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 1012-1234 | 2.3e-22 | 74.4 | In-house | 57-280 (307) | alignment | ||
Range on Protein: 1012-1234
Range on HMM: 57-280/307.0
RVVLN--KKTEDFIHASYINGYQEARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPATYDSERhfdFYRIKHHEMNIDNYYTQ
|.|.. . |.||| |. . . ||.|. | . | .||.|....| ..|||...|. | ||||. . . . . ....| ..
rivvkfdglasdyihanylgiaikpkkficaqgplentqysfwamaiqekvesvimlckvielakikceqywpleegqkl...vfgeapntisvanlgak
TILRvlDTQAGEEQTIILIQ---------LPLSNIVSDELSHTErvgiLSAIQEIEKIQRKTgnNPILVHCSDTVSRSGVFC-VLYTSIQQMKIEQQVNI
.. | . . |. . | .| ... |.|| .| .. .| ||..|||| | ||| . . . .. . ..
klap..dedlinvttlkvdwaqksrtiqhlqwenwpdrgvpqin....ltainlleavrydt..npvvvhcsaGvGrsGtivaislvqdkmiaGinckdm
YEILYNMRTCKPGLITTPVQYKMVYLLLMRYVEEF
... ..|. .. | | .|| .. .|. | |
kklveelrsqrhyaiqteaqylylhrvlleyflel
|
|||||||||
subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 1009-1233 | 3.6e-22 | 73.5 | In-house | 61-289 (305) | alignment | ||
Range on Protein: 1009-1233
Range on HMM: 61-289/305.0
DEYRVVLNK-KTEDFIHASYINGYQEARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPATYDSERHFDfyrIKHHEMNIDNYY
|. || |. ..||| |. ... || ...| . | |.|| | ...| | |||...| |..|... . . .|. | . . .
dnnrvklegpwpheyihanyvstptnpkrfictqaplektcadfwymclqdkveaifmlcnllekgakkcleyfaskdkdvlefe...ekgqkisvkfes
TQTILRVLDTQAGEEQTIILIQLPLSNIVSDELSHTE---RVGILSAIQEIEKIQR--KTGNNPILVHCSDTVSRSGVFCVLYTSIQQMKIEQQVNI-YE
..|. . |..| ..|...|. | .. | |. .| . | .. .. || |||| . |.| .| ..|. |...
svtlkfrkdakakvtetvlviegpgekarkvthyhwidwpdrgvpaadlailellekarpskgpivvhcsagigrtgsvvmleyildqllagqiiedtdk
ILYNMRTCKPGLITTPVQYKMVYLLLMRYVEE
|| .| . | | || .|. ... |...
ilqkireqrnnsiqtdaqylfvhqvilnyfrk
|
|||||||||
0048179 | (Phosphotyrosine protein) phosphatases II | 827-933 | 7.3e-22 | 73.1 | In-house | 38-139 (144) | alignment | ||
Range on Protein: 827-933
Range on HMM: 38-139/144.0
SSSSSDNSHKTIHHYLFKCWPDHGVPATPTSTHSFYEQIKMWLDLPPPVLIHCSGGIGVTGMLISIMIGIeqglsTGGVDVMAIVNKMRSQRMNMIQTEE
.. . .....||. ||||||| .. .|.| |. .|. . |||.|||.|.| ||.|. . . . . |... ... .||.|........
eeyepefleregiqylhlpwpDhgvpdllellleflefieealeeggpvlVHCsaGvgRtgtlvaaylmk.....klglsleealalvrsrrpgavpnpg
QYQFVHY
|..|...
qlrfLle
|
|||||||||
subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 1009-1230 | 5e-21 | 70.0 | In-house | 56-270 (288) | alignment | ||
Range on Protein: 1009-1230
Range on HMM: 56-270/288.0
DEYRVVLNKKTEDFIHASYINGYQEARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPATYDSERHFDF--YRIKHHEMNIDNY
| || |. .. .|.| . . | .| |..| . | ..| |.... |||||...| . .|.| . .. .|.. .||
ditrvklsddpdfyiaanvvssakykrrlicaqaPlngtieelWkmllesdveyivmlcellekGkeksaeyfPsklGekarigrlctvvkkkradidkl
YTQTILRVldTQAGEEQTiILIQLPLSNIVSDELSHTervgILSAIQEIEKIqrKTGNNPILVHCSDTVSRSGVFCVLYTSIQQMKIEQQVNIYEILYNM
. ..||. .. |||. |. .| | . | . . || .. .| . |. ..||.||.| | |.| . . ....... .. | ..| ..
vkvsllri..skegeekv.ivkilhlleWdddgvPen....ylsplrllevl..kslqkPivvhssaGvGrtgtlililialeslrlddflgirsllakl
RTCKPGLITTPVQYKMVYLLLMRY
| . |.| || |. ... .
reerfkaiqtemqylyvhrcvlee
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 696-861 | 7.4e-21 | 69.1 | In-house | 26-186 (319) | alignment | ||
Range on Protein: 696-861
Range on HMM: 26-186/319.0
SENKKRNRFKTILPYDNNLLTLRPISSrgDCSHSYINASYIDGYKKKH-QFIATQGPLPQTLVDFWRLIWQEDICCILMMLSiTSDGGIVRCQQYWPDAI
|...|. ..| . .|. |.. | . |..|||. ||.. . ..||.| .| .. ||||..|. |. . . |. || .| .|.|
vtskdksrvinvvPlPetrvvlqrigd..ddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltd.lselGikvcaeylPtke
GVA--AFYGPFKIIVEGindNKVSEERIIKLSMTSsSSSDNSHKTIHHYLFkCWPDHGVPATPTSTHSF
. || ... . | ..| .. .| . .. . . || . |.. .||| ... .
tldntslyGdilvtlkg...revkdryaistlllk.rvdkeesrelthywy.kwleaevPaeeaaliam
|
|||||||||
subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 691-943 | 9.8e-21 | 68.7 | In-house | 36-280 (312) | alignment | ||
Range on Protein: 691-943
Range on HMM: 36-280/312.0
EVANCSENKKRNRFKTILPYDNNLLTLrpissRGDCsHSYINASYIDGYKKKHQFIATQGPLPQTLVDFWRLIWQEDICCILMMLSITSDGGiVRCQQYW
|.. | ||. | .| .|| || || | .. | .|..||||| .| . ||.| ..|... .. || .| .|
ectaflkfkdlnrypniqcwdrgrftl.....agde.nfyihanfvkictkperfvctqgplentcthfwqlalslgstsiillcgfvedgs.ekcakyi
PDAIGVAAFYGpFKIIVEGIND---NKVSEERIIKLSMTSSSSSDNSHKTIHHYLFKCWPDHGVPATPTSTHSFYEQIKMwlDlPPPVLIHCSGGIGVTG
| .| . .. | . | ..| . . . . || . |||||.| . ... . .| | ||. ||| |.| ||
sdivgfvdled.hrvyteycteieiggkskdkithrvlkvvvkatgqesklnhyqwaswpdhgmpdscdtalrllsavkk..d.kkpviahcsagvgrtg
MLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEAFYTIG
|. | | .| . .| .| ... || .. ..|| .|. |
tlaliesmiaalrhprkqnvkdsfvllrkdrarsvrvfpqyvyalrcvleflyskg
|
|||||||||
subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 1014-1229 | 4.4e-20 | 66.5 | In-house | 60-267 (281) | alignment | ||
Range on Protein: 1014-1229
Range on HMM: 60-267/281.0
VLNKKTEDFIHASYINGYQEARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPATYDSERHFDFYRIKHHEMNIDNYYTQTILR
. ||.. |.||| || | .|... | | | |.|| || ... . |||||...| . . | .|.| .|| . ... . ... | |
mpnknstdyihanyirspflkrgyiltqgpkketradfwrmiwqenttaivmlcqfletnrekcaeyfprnahcclqfdklsvsyedstvnkslvttrln
VldTQAGEEQtiiLIQLPLSNIVSDE-LSHTERVgILSAiqeIEKIQRKtgNNPILVHCSDTVSRSGVFCVLYTSIQQMKIEQQV-NIYEILYNMR-TCK
. . || . || | . | . .. | .| . ||. . | ..||| | ||| . . ..| .. . .| .|. .| | .
l..syegetr...lithwlwkewpdwqvpessev.mlki...lrkirar..stppvihcsagvgrsgtlmaveialqsihshftlpdikqivshlrvtgr
PGLITTPVQYKMVYLLLMR
. | || ... .|.
aasvqtlqqymliwkvlld
|
|||||||||
subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 736-932 | 7.2e-20 | 65.6 | In-house | 83-281 (302) | alignment | ||
Range on Protein: 736-932
Range on HMM: 83-281/302.0
IDGYKKKHQFI-ATQGPLPQTLVDFWRLIWQEDICCILMMLSITsDGGIVRCQQYWPDAIGVAAFYGPFKIIVEGINDNK--VS---EERIIKLSMTSSS
.|| .||.. | .|| .| || | ... . . |. ... .| .|. | .| .| . . .... . . .. .. .. .
mdGtekkekvskkpivpkkstlekhwalieqynvaivvqlcsfv.edeekkcaeyysdkvggelkfgrytvktvsvktdleeftdkksfklytveiknek
SSDNSHKTIHHYLFKCWPDHGVPATPtstHSFYEQIKMWLDLPPPVLIHCSGGIGVTGMLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQ
.. .||.. .| .||||| |. . .. . .| ||.||| |.| || |..| ||. . |.. || .|. | .|.|.|
kkkkvkktvdilafsawpdhGapkea...ytaldilkfcesykknvlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqdeqqli
FVH
..
yll
|
|||||||||
subfamily_egg_pd | Subfamily egg | 1019-1230 | 1.1e-19 | 65.2 | In-house | 67-269 (307) | alignment | ||
Range on Protein: 1019-1230
Range on HMM: 67-269/307.0
TEDFIHASYINGYQEARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMevDTCYQYWPATYDSERHF--DFYRIKHHEM--NIDNYYTQTILRV
..||||| ...| ||.|..| | | .|| |. .... |||| .| . | ||| . . . .||. .. . | .. | |..
lddfihanrvkGkpllnefilaqaplkntvddfwrmvfqeevqyivmltsrkes..erceyywpkaesdslvtvpGslrienlkvdskadplfrvtklkl
LDTQaGEEQTIILIQLPLSNiVSDelshtervgILSAIQeIEKIQRKTgNNPILVHCSDTVSRSGVFCVLYTSIQQMKIE--QQVNIYEILYNMRTCKPG
. .. ||. . | . | .|| . | .. . . |. .|..|.. . ||..... . ... .. . . . .| ..
vGgd.deerflehwqgdvnn.ssd.........vysplr.vlrklrnl.skpvvvqdilGvskaatlvaieiallsllrGpitkslvlravvflrlrrrl
LITTPVQYKMVYLLLMRY
. ....| .|| |.. .
svesvllylfvyrlvlff
|
|||||||||
subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 1020-1219 | 1.1e-19 | 65.3 | In-house | 75-269 (301) | alignment | ||
Range on Protein: 1020-1219
Range on HMM: 75-269/301.0
EDFIHASYINGYQEARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPATYDSERHFDFYRIKHHEMN--IDNYYTQTILRVLDT
||| .|. ... ||.. .| | |. .|| |.| . ||||. || ... | .| | . .. . . ..|| .... ... .. |.| |.
rvPihanwiptsGhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkisekldigrfkikiknkelilnkkiskrtleveds
QA-GEEQTIILIQlpLSNIVSDEL--SHTERVGILSAIqeiekiqrKTGNNPILVHCSDTVSRSGVFCVLYTSIQQMKIEQQVNIYEILYNMRTCKPGLI
. .|.. | |. .. ||.| .. . | ..||.||||. . || | .... ...... | | ..| . .
tgkfatrtvthyq..ysewtdrgvPkshaelfdlmelv........kksekPivvhcsaGiGrsvafigteylareveadptieltealkhlrehrwngv
TTPVQ
| |
qtnsq
|
|||||||||
subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 1019-1236 | 1.5e-19 | 65.3 | In-house | 45-265 (290) | alignment | ||
Range on Protein: 1019-1236
Range on HMM: 45-265/290.0
TEDFIHASYINgYQEARSFIVAESPTKL-------TAANFWSMIVKNKCSVIVMLCDIVEMEVD----TCYQYWPATYDSERHFDFYRIKHHEMNIDNYY
..|.|||... . . .|. .|| . | .|| |. . | .||||. | . . .| .| | . . | |. .| .. ..
nddyiHAnrvt.cpnglrliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCakYvpesvgeelkfkgltvkCkskekeddv
TQtilRVLDTQAGEEQTIILIQLPLSNIVSDElSHTERVGILSAIQEIEkiqrkTGNNPILVHCSDTVSRSGVFCVLYTSIQQMK-IEQQVNIYEILYNM
. | | . ..|. . |.. . . . .||.|| .. . . |..||| | .||| .. . . | . ...|.. ..|...
et...RelvvkfddeeeftvtHsllkgWnkln.vqedtktllsliqkvk.....asktpvivHcvdGiSrsAalaaiilgyQkiaetsgsvkledvlkal
RTCKPGLITTPVQYKMV-YLLLMRYVEEFEA
| . .||.. .. | . .... .|. ..
rkqralaitsalelafvdagivllaievldq
|
|||||||||
subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 996-1225 | 1.9e-19 | 64.4 | In-house | 45-230 (392) | alignment | ||
Range on Protein: 996-1225
Range on HMM: 45-230/392.0
NLPLVRSDLYLPPDEYRVVL----NKKTEDFIHASYINGYQEARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEvdtcyqywpatydserhf
||. | . || |. ||.| . .|.. ||||.... ...| ...| . .||.|. ... . |.|. .. | .
nlkknryknilpydsarvkleviddipdsdylnasyipsfdnekayiasqgpnaaslddfwrmvfqenvttiamvtklkegd..................
dfyrikhhemnidnyytqtilrvldtqAGEEQTIiLIQLPLSNIVSDE-LSHTErvGILSAIQEIeKIQRKTGNNPILVHCSDTVSRSGVFCVLYTSIQQ
|... | ... .. || .| |.|. |.. |...||| | |.|| . . . .
...........................kgddart.vaqfhftewPdkdvpkhts..sllkfikev.kadfGqythpliihcsagvgrtgvvisidsvvah
MKIEQQVNIYEILYNMRTCKPGLITTPVQYKMVYL
| . |...... |.| .| .. | || ..|
akktrmvdvfnfvtnirrkrpymvqtkeqyafiyg
|
|||||||||
subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 728-945 | 3.2e-19 | 64.2 | In-house | 46-265 (290) | alignment | ||
Range on Protein: 728-945
Range on HMM: 46-265/290.0
HSYINASYIDgYKKKHQFIATQGPLPQT-------LVDFWRLIWQEDICCILMMLSITSDG---GIVRCQQYWPDAIGVAAFYGPFKIIVEGINDNKVSE
|| |... . . ..|.|| |. .. . .|| .. || . . |. . . . |..| |...| .. ... .. |
ddyiHAnrvt.cpnglrliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCakYvpesvgeelkfkgltvkCkskekeddve
ERIIKLSMtssssSDNSHKTIHHYLFKCWPDHGVPATPTSTHSFYEQIKmwlDLPPPVLIHCSGGIGVTGMLISIMIGIEQGL-STGGVDVMAIVNKMRS
.| . . |. . |. |.|.| | . |. .. . | ...| ||..|| || .| .| .| ..| | . ......|.
tRelvvkf.....ddeeeftvtHsllkgWnklnvqedtktllsliqkvk...asktpvivHcvdGiSrsAalaaiilgyQkiaetsgsvkledvlkalrk
QRMNMIQTEEQYQFVHYVLLEAFYTIGKE
|| ..|...... || .... . ....
qralaitsalelafvdagivllaievldq
|
|||||||||
PTPc_DSPc_SM00012 | 1146-1228 | 7.7e-19 | 63.2 | In-house | 20-104 (105) | alignment | |||
Range on Protein: 1146-1228
Range on HMM: 20-104/105.0
VGILSAIQEIEKIQRKTG-NNPILVHCSDTVSRSGVFCVLYTSIQQMKIE-QQVNIYEILYNMRTCKPGLITTPVQYKMVYLLLM
||.......| ..| . ..|..||||. |.|.|.|..|.. .||.. | ..|.|..|. .|. .||...| || ..| |.
dsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylflyrall
|
|||||||||
subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 740-933 | 1.2e-18 | 62.0 | In-house | 2-198 (199) | alignment | ||
Range on Protein: 740-933
Range on HMM: 2-198/199.0
KKKHQFIATQGPLPQTLVDFWRLIWQEDICCILMMLSITsDGGIVRCQQYWPDAIGVAAFYGPFKIIVEGINDNkvSEERIIKLSMTSSSSSDNSHKTIH
| ....|||| || .|. |||...|. |.|. . ||| . .. || . . .. | . .. | | .|..... | . |
kgqrryiatqhplretmadfwqmvwetgsghivmvnddq.knkeadypfywpttesgtgkygslsvttktittk..pdytitaliltnnttappstreis
HYLFKCWPDHGVPATPTST----HSFYEQIKMWLDLPPPVLIHCSGGIGVTGMLISIMIGIEQ--GLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHY
|| | | .. | | | . ||..||| | | ||..... ||. | ||.. . ...| | .| . ..|.|..
hyqftswkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiyq
|
|||||||||
subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 742-933 | 2e-18 | 61.3 | In-house | 3-197 (198) | alignment | ||
Range on Protein: 742-933
Range on HMM: 3-197/198.0
KHQFIATQGPLPQTLVDFWRLIWQEDICCILMMLSITsDGGIVRCQQYWPDAIGVAAFYGPFKIIVEGINDNkvSEERIIKLSMTSSSSSDNSHKTIHHY
....|||| || .|| |||...|. |.|. . ||| . .. || . . .. | . .. | | .|..... | . | ||
qrryiatqhplretladfwqmvwetgsghivmvnddq.knkeadypfywpttesgtgkygslsvttktittk..pdytitaliltnnttappstreishy
LFKCWPDHGVPATPTST----HSFYEQIKMWLDLPPPVLIHCSGGIGVTGMLISIMIGIEQ--GLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHY
| | .. | | | . ||..||| | | ||..... ||. | ||.. . ...| | .| . ..|.|..
qftswkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiyq
|
|||||||||
subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 973-1232 | 3.9e-18 | 59.9 | In-house | 30-286 (302) | alignment | ||
Range on Protein: 973-1232
Range on HMM: 30-286/302.0
AHYKALQVLTVKPNSvLRNFgLSNLPLVRSDLYLPPDEYRVVLNKKTEDFIHASYINGYQEARSFIVAESPTKLTA---ANFWSMIVKNKCSVIVMLCDI
. .|... . |. .. . | .|| .|. . .|. .| |... .....|| .. . || |.| |.. .. ..|| |. ..|. .|.|
kefkkidtmkvdlek.Ckaf.kknlkknqsedvpildsnlvkleaepdsyvnaskvevPeltrsiilaQlpkvdsedsveeFWrmvfqekivsvvilvge
VEMEVdTCYQYWPATYDSERHFDFYRIKHH--EMNIDNYyTQTILRVLDTQAGEEqTIILIQLpLSNIVSDELShtERVGilSAIQEIEKI--QRKTGNN
|.. | ...| . .. ... .. | .. |. .. || . .. ... |.| ... .... ..|....|. . ...
eelkk.tlselfpkksgdykeygkmfvNnrkVekaeeek.tryviEvlPegcsns.vlanvyv.ltnWkqkkvp..vkya..eliktaakvfakkikade
PILVHCSDTVSRSGVFCVLYTSIQQMKIEQQVNIYEILYNMRTCKPGLITTPVQYKMVYLLLMRYVE
.... . | |.| .| ....... ....|| ||. ..|. .| . . || ..|. |. |.
ntvivSknGaGRagafltlavaveklqkgkepnikeivksiRsqRpravdslkQyvslyialllyik
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 693-792 | 3.3e-17 | 57.2 | In-house | 42-152 (350) | alignment | ||
Range on Protein: 693-792
Range on HMM: 42-152/350.0
ANCSENKKRNRFKTILPYDNNLLTLR--PISSRG---DCSH-SYINASYIDGY----KKKHQ--FIATQGPLPQTLVDFWRLIWQEDICCILMMlSITSD
.. | .||.| ||||. . |. . || . .| ||||.|. . . . .||||.|||.|. ||...| . .. ||.. . .
seGvelfaknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsl.tsdve
GGIVRCQQYWPD
.. .|..||..
lnlekcyrYWqe
|
|||||||||
subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 1017-1230 | 5.3e-17 | 56.3 | In-house | 76-289 (310) | alignment | ||
Range on Protein: 1017-1230
Range on HMM: 76-289/310.0
KKTEDFIHASYINGYQEARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPATYDSErHFDFYRIKHHEMNIDNYYT--QTILRV
. ||.||| |.. .||... | . | .|| || .... |..|| ..| | |||. .| . |. ... .. |
sryedyihanyvktnylrstficsqgplqhtiidfwrmifqeraesilllckvgeegrpkcvgywpslgvte.tygcirvtnlsesseefeicnlavtfv
LDTQAGEEQTIILIQLPLSNIVSDELSHTErVGILSAIQEIEKIQRKTGNNPILVHCSDTVSRSGVFCVLYTSIQQMKIEQQVNIYEILYNMRTCKPGLI
| .|| | .| .| | . . | ... . | .|||| . | .| . | .|.... ..|.. |. ... . |
pdnvpvdeqpanlkelrvslikwpnwpdrg.vpdekchtvpqrllaqvrhgpcvvhcsagkdrlyvvvalklkidkldrglkvdaeevktellksraici
TTPVQYKMVYLLLMRY
|..|| .. . . .
qtelqyliidrvriif
|
|||||||||
subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 1017-1233 | 2.8e-16 | 54.0 | In-house | 76-291 (305) | alignment | ||
Range on Protein: 1017-1233
Range on HMM: 76-291/305.0
K-KTEDFIHASYINGY-QEARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPATYDSERHFDFYRIK-----HHEMNIDNYYTQ
| |.||| |. . ||.|. | | .|| |...|| ||||| ||. | |||||. ... . . |. |.
kpspsdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkveqivmlcktvelgklkcaqywpaaqgeklelksgivvenvsgskpmerdaeiqi
TILRVldtQAGEEQTIILIQLPLSNIVSDELSHTErvgiLSAIQEIEKIqrKTGNNPILVHCSDTVSRSGVFCVLYTSIQQMKIEQQ-VNIYEILYNMRT
|.|.. .|.. . .| .. . |.... . | . . ||.|||| . |.| . .... ... . |.. .|
tllnl...tysgdqkmsvrhlqwtewpdrgvppck....ltslellsai..rgskvpivvhcsagigrtgtivaieyilekiaenkpcppmpelvkalrd
CKPGLITTPVQYKMVYLLLMRYVEE
. | . ||| ... ... |. |
qrafsiqndvqylfihrvmlnyfle
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 1016-1126 | 1.5e-15 | 51.7 | In-house | 52-167 (319) | alignment | ||
Range on Protein: 1016-1126
Range on HMM: 52-167/319.0
NKKTEDFIHASYINGYQEAR-SFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPA--TYDSERHFDFYRIK-HHEMNIDNYYTQTI
... . ...|||. ||..|. |.| |. . . ....|| .. ... ||| |.|. | .. | .|.|. | |... . ... . |.|.. |.
dddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlselGikvcaeylPtketldntslyGdilvtlkgrevkdryaistl
-LRVLDTQAGEEQTII
|. .| . | |
llkrvdkeesrelthy
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 833-940 | 1.7e-15 | 51.3 | In-house | 86-195 (440) | alignment | ||
Range on Protein: 833-940
Range on HMM: 86-195/440.0
NSHKTIHHYLFKCWPDHGVPATPTSTHSFYEQIKMWLD--LPPPVLIHCSGGIGVTGMLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQF
.|...| .. |||.||| . .... . |.|.||| | | ||..|.. . . . .|.....| ||..| .|.|| ||| |
iesrtlkqyhyqgwpdkgvpkfagpvlkmiqdvnesqekagngpllvhcsagagrtgviiavdsilreakrsdqidifsfinsmrnnrpqmvqtpeqyaf
VHYVLLEAFY
|| ..||..
vheavlegll
|
|||||||||
subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 1044-1231 | 3.6e-15 | 50.7 | In-house | 37-221 (255) | alignment | ||
Range on Protein: 1044-1231
Range on HMM: 37-221/255.0
TKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPATYDSERHFDFYRIKHHEmNIDNYYTQTIlrVLDTQAG-EEQTIILIQLPLSNIVSDELSH
|| ..|. .||..| .|.||||| | .|. | .|.| | . . . . .. . .|. .. .. | .| . . .
ysltvdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdeklkladvnvtttk.ssadvvlrtl..eitstlgekkkthtvkhysykGWieknaPe
TERvgilsAIQEIEKIQRKTgnNPILVHCSDTVSRSGVFCVLYTSIQ----QMKIEQQVN--IYEILYNMRTCKPGLITTPVQYKMVYLLLMRYV
| |..| |. |.. ...|||| . || | . | ... . |. ..| ..| ... | ||.| . |... .|
lar.....eilnilkvvrds..ksvvvhCstGiGrsaafvlaelvyqkmirsldttetveldylslleelrskrkraihtPlqlafsilmvldlv
|
|||||||||
subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 675-936 | 1.3e-14 | 48.4 | In-house | 29-282 (302) | alignment | ||
Range on Protein: 675-936
Range on HMM: 29-282/302.0
KSEFQRLQNFghlfSTEVANC---SENKKRNRFKTILPYDNNLLTLrpissrGDCSHSYINASYIDGYKKKHQFIATQGPLPQTL---VDFWRLIWQEDI
|.||...... ... .| .| |.|. . . .|.||. | . . ||.||| .. . ... | .| | .. .|||...|| |
kkefkkidtm....kvdlekCkafkknlkknqsedvpildsnlvkl......eaepdsyvnaskvevPeltrsiilaQlpkvdsedsveeFWrmvfqeki
CCILMMLSiTSDGGIvRCQQYWPDAIGVAAFYGPFKIIVEGINdnKVSEER-IIKLSMTSSSSSDNSHKTIhhYLFKCWPDHGVPATPTSTHSFYEQI-K
. ... . . ....| | || . . . .. |..||. . . |. .. |... |... || ... ... .
vsvvilvg.eeelkk.tlselfpkksgdykeygkmfvNnrkVe..kaeeektryviEvlPegcsnsvlanv..yvltnWkqkkvpvkyaeliktaakvfa
MWLDLPPPVLIHCSGGIGVTGMLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLL
. ...| |.| |.... .. .|. . . . ||...|||| ..... .|| ... .||
kkikadentvivSknGaGRagafltlavaveklqkgkepnikeivksiRsqRpravdslkQyvslyiall
|
|||||||||
subfamily_ptpA1_pd | Subfamily ptpA1 | 1014-1186 | 1.4e-14 | 48.7 | In-house | 69-251 (418) | alignment | ||
Range on Protein: 1014-1186
Range on HMM: 69-251/418.0
VLNKKTEDFIHASYINGYQeARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPATYDSER---------HFDFYRIKHHEMNID
. .|. |.| | ||.| . ||... | | |.|| |. .|.| .|||| | | .||| |. | | .. |. |
iqdkegsdyinanyidgay.pkqfictqgplpntiadfwrmvwenrcriivmlsresencrikcdrywpeqiggeqfsiygngnevfgtysvelveviqd
NYyTQTILR-VLDTQAGEEQTIILIQL---PLSNIVSDELSHTERVGILSAIQeIEKIQRKTGNNPILVHCSDTVSRSGVFCVLYT
. | | . | || . | | | || . . .. | . | | ||.|||| | |.| ||
pe.reiitrnirltfegetrditqyqyegwpdhnipdhtqpfrqllhsitnrq.nqiipssdrnvpiivhcsagvgrtgtfctavi
|
|||||||||
0048076 | (Phosphotyrosine protein) phosphatases II | 1103-1230 | 1.7e-14 | 49.2 | In-house | 25-142 (145) | alignment | ||
Range on Protein: 1103-1230
Range on HMM: 25-142/145.0
IDNYYTQTILRVLDTQAGEEQTII-LIQLPLSnivsDELSHTERVGILSAIQEIEKIQRKtgNNPILVHCSDTVSRSGVFCVLYTSIQqmkieQQVNIYE
. .. |.|.. ... ..|...| ...||. | . .|.... ||..... ..|.||||| |.|.|.....| .. ..|...|
lkdlgittvlnltselellerlgiqylylpwp....Dhgvpdllellleflefieealke..ggpvlVHCsaGvgRtgtlvaaylmll.....lgvslee
ILYNMRTCKPGLITTPVQYKMVYLLLMRY
.| .|.. || ...| |....|......
alelvrsqrpgavpnpgqlrflyefelel
|
|||||||||
subfamily_hpo-7_pd | Subfamily hpo-7 | 1047-1244 | 5.6e-14 | 46.7 | In-house | 46-240 (263) | alignment | ||
Range on Protein: 1047-1244
Range on HMM: 46-240/263.0
TAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPATYDSERHFDFYRIKHHEMNIDNY-YTQTILRVLDTqAGEEQTIILIqlplsniVSDELSHTER
| ..|...||..| .|.||||| | .|. | .|.| | . . . .. | |. .| .|. . .|. ...
tidkfyqtivqtktevvvmLcDfneegvekcssyfPlekdekqklanvnvcttkvqsdvllktlellstlge.Kkkthtvkhy.......sykgWieknd
VGILSAIQEIEKIQRKTgnNPILVHCSDTVSRSGVFCVLYTSIQ----QMKIEQQVNI--YEILYNMRTCKPGLITTPVQYKMVYLLLMRYVEEFEAYGN
. | .| |. |. .. |||| . || | | . | ... . |.. ..| ..| ... | ||.| . |... .| . | |.
pelareilnilkvarns..kslvvhcstGiGrsaafsvaElvyqkmirsldttstveldylsLleelrssrkraihtPmqLafsilmvLdfvlnnfakge
FEGQK
| .
leaky
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 1017-1106 | 6.2e-14 | 46.5 | In-house | 80-175 (350) | alignment | ||
Range on Protein: 1017-1106
Range on HMM: 80-175/350.0
KKTEDFIHASYINGY----QEARSF--IVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPATYDSERHFDFYRIKHHEMNIDNY
.|.|.| |.|.. . .| | . .|.. | .|. .|..|| ||..| . ||.... ||.||. .. . . .. |.|..
lstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcyrYWqegsydditvklaskwenimginds
|
|||||||||
subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 697-939 | 7.5e-14 | 46.0 | In-house | 46-279 (303) | alignment | ||
Range on Protein: 697-939
Range on HMM: 46-279/303.0
ENKKRNRFKTILPYDNNLLTLrpissrgdCSHSYINASYIDGYKKKhQFIATQGPLPQTLVDFWRLIWQEDICCILMMLSiTSDGGIVRCQQYWPDAIGV
.| ..||| .. | . | . ||| |||.. .| . | || ||..| |||..| .. . |.|..|. |. . . .|
knmdknrfvdvicldhskvkl........sdssyihasyleldssk.kailtqlplshtaadfwqmiieqkvkcvllllt.dseydklggdsvfprnqdf
AAFYGPFkIIVEGINDNKVSEERIIKLsMTSSSSSDNSHKTIHHYlfKCWPDHGVPAT--PTSTHSFY---EQIKMWLDLPPPVLIHCSGgIGVTGMLIS
| . | | .. .... .|. .. | . .| .||| | || .|. | . . .. . | |.| . || | .| .
lkfeers.irvgefkrvelgdgwvlkv.lsvsngdyksflhvhhy..kawphnsipsdgspkfvkqiwqlqsvlrkysdstptvymslsg.cgragtfal
I-MIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEAF
. . .|.. ....| |. .| |. .|. .| |
fetahlslhseqasldlvkclenvrngrlhavqnlsqfsvvytllaehv
|
|||||||||
subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 747-944 | 8.8e-14 | 46.2 | In-house | 39-226 (255) | alignment | ||
Range on Protein: 747-944
Range on HMM: 39-226/255.0
AtqgplpqTLVDFWRLIWQEDICCILMmLSITSDGGIVRCQQYWPDAIGVAAFYGPFKIIVEGindnKVSEERIIKLSMTSSSSSDNSHKTIHHYLFKCW
|. |.. | | . . | |. . |...|..|.| . .... ... . | .|| . .|..|| .| |
l.......tvdkfyqtivqtktevvvm.lcdfaeegvekcssyfplekdeklkladvnvtttk....ssadvvlrtleitstlgekkkthtvkhysykGW
PDHGVPATPTSTHSFYeqiKMWLDLpPPVLIHCSGGIGVTG------MLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEAFY
... | . . |. | .|..||| ||| . .. || . .|...| . .....||.| |.| | | ...|. ..
ieknaPelareilnil...kvvrds.ksvvvhCstGiGrsaafvlaelvyqkmirsldttetveldylslleelrskrkraihtPlqlafsilmvldlvf
TIGK
|.
pkge
|
|||||||||
0048179 | (Phosphotyrosine protein) phosphatases II | 1138-1225 | 1.3e-13 | 46.3 | In-house | 59-139 (144) | alignment | ||
Range on Protein: 1138-1225
Range on HMM: 59-139/144.0
DELSHTERVGILSAIQEIEKIQRktGNNPILVHCSDTVSRSGVFCVLYtsiqQMKiEQQVNIYEILYNMRTCKPGLITTPVQYKMVYL
| . .|.... ||.... ..|.||||| |.|.|.....| || .......|.|. .|.. || ...| |......
Dhgvpdllellleflefieeale..eggpvlVHCsaGvgRtgtlvaay....lmk.klglsleealalvrsrrpgavpnpgqlrfLle
|
|||||||||
subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 1034-1224 | 1.6e-13 | 45.3 | In-house | 4-197 (199) | alignment | ||
Range on Protein: 1034-1224
Range on HMM: 4-197/199.0
ARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEM-EVDTCYqYWPATYDSERHFDFYRIKHHEMNIDNYYTQTILRVLDTQAGEEQTIILIQLPL
| .|... | . | |.|| |. . |||. | |.| . |||.| . .. . . . || | | . . . | . . .
qrryiatqhplretmadfwqmvwetgsghivmvnddqknkeadypf.ywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqf
SNIVS-DELSHTERVGILSAIQEIEKIQRKTGNNPILVHCSDTVSRSGVFCVLYTSIQQMKIE--QQVNIYEILYNMRTCKPGLITTPVQYKMVY
. . ||.. | .|. | . . |..||||| .||| | .. . |...|. .| .. |.|.. .|...|
tswkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiy
|
|||||||||
subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 1034-1224 | 1.8e-13 | 45.2 | In-house | 3-196 (198) | alignment | ||
Range on Protein: 1034-1224
Range on HMM: 3-196/198.0
ARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEM-EVDTCYqYWPATYDSERHFDFYRIKHHEMNIDNYYTQTILRVLDTQAGEEQTIILIQLPL
| .|... | . | |.|| |. . |||. | |.| . |||.| . .. . . . || | | . . . | . . .
qrryiatqhplretladfwqmvwetgsghivmvnddqknkeadypf.ywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqf
SNIVS-DELSHTERVGILSAIQEIEKIQRKTGNNPILVHCSDTVSRSGVFCVLYTSIQQMKIE--QQVNIYEILYNMRTCKPGLITTPVQYKMVY
. . ||.. | .|. | . . |..||||| .||| | .. . |...|. .| .. |.|.. .|...|
tswkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiy
|
|||||||||
I-set | Immunoglobulin I-set domain | 534-615 | 4.9e-13 | 40.7 | Pfam-A | 3-86 (90) | alignment | ||
Range on Protein: 534-615
Range on HMM: 3-86/90.0
LLSTTKDINAAKGDDIVLKLCVGGEPRPDVTWFFNNQIIGDDEHYEMSEED--NTLLIHDILPMHAGVYNYTASNLLKSISGQI
. . ||... .|... |. | ||| |.|.|. ... . ........|. || |... . .| |. .|.| ... . ..
ftqklkdvevseGesvelectveGepepsvsWakdgselkssqrvkvtveeaeytLtIsnvevsDeGkYtckatnsagkaeaka
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 1009-1108 | 4.9e-13 | 43.6 | In-house | 46-149 (297) | alignment | ||
Range on Protein: 1009-1108
Range on HMM: 46-149/297.0
DEYRVVLNK--KTEDFIHASYINGYQEAR--SFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPATYDSERHFDFYRIKHHEMNID
|. || | . .|.| | |. .| .|.|. |.. | .|| ..... ||||.. . | | |. ||| . . .. . ... |
ddtrvkllrviterdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrdkcapywpsvvqerlkagdvvveflsstsd
NYYT
.. .
efdr
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 1148-1225 | 8.1e-13 | 42.5 | In-house | 111-188 (440) | alignment | ||
Range on Protein: 1148-1225
Range on HMM: 111-188/440.0
ILSAIQEIEKIQRKTGNNPILVHCSDTVSRSGVFCVLYTSIQQMKIEQQVNIYEILYNMRTCKPGLITTPVQYKMVYL
.| ||.... | |.|| |.||||| ..|.|| .. . ... | .|..|. .. .|| .| .. || || .|.
vlkmiqdvnesqekagngpllvhcsagagrtgviiavdsilreakrsdqidifsfinsmrnnrpqmvqtpeqyafvhe
|
|||||||||
fn3 | Fibronectin type III domain | 399-477 | 1.5e-12 | 40.7 | Pfam-A | 5-85 (85) | alignment | ||
Range on Protein: 399-477
Range on HMM: 5-85/85.0
NLTASV-GLITAQLSWNEPNSTNGIINNYIILISTSSSSS-SSVRNLSTGNKIIDIKELLPNMGYTFSVAAVNEGGIGQRS
||..| . ...|||..|.. .| | .| . ....... . .... . ...| |.. |.|.|.|||..| |..|
nlsvsevtstsltlsWsppkdgggpitgYeveyrekgggeewkeftvprtttsvtltgLkpgteYefrVqavngagegpeS
|
|||||||||
subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 695-851 | 2.1e-12 | 41.2 | In-house | 93-235 (244) | alignment | ||
Range on Protein: 695-851
Range on HMM: 93-235/244.0
CSENKKRNRFKTILPYDNNLLTLrpisSRGDCSHSYINASYIDGYKKKHQFIATQGPLPQTLVDFWRLIWQEDICCILMMlsitsdGGIVRCQQYWPDAI
.| .|| . ||.| | . | |.| . .|||||.. . ..| || || .| .|||... . . .... | . ..||||.
npnnswknregaglpfdfnrvpl....skgsmgntyinasfvgclgrtaeyiltqhpladtsmdfwkmmlerhvnvlvvl......gsveeedeywpdse
GVAAFYGpfKIIVEgINDNkvSEERIIKLSM-TSSSSSDNSHKTIHHYLFKCWPDHGV
. . | | . | | . || | | ..||... . || |
plewyee..ditvt.ltdr..defknikasnleiesdmneshqaltmfqisnwpsdgt
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 737-812 | 9.3e-12 | 39.0 | In-house | 230-300 (440) | alignment | ||
Range on Protein: 737-812
Range on HMM: 230-300/440.0
DGYKKKHQFIATQGPLPQTLVDFWRLIWQEDICCILMMLSITsDGgivRCQQYWPDAIGVAAfYGPFKIIVEGIND
.|| || ||||| || |..|||||. . | |.|. . | | ||| . .||| . | ..
egyskknafiatqmpldstvldfwrlvhdyristiimlnqln.dk...tcsiywpvntrsvt.fgpftvghkgsen
|
|||||||||
subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 1041-1228 | 3.5e-11 | 37.1 | In-house | 97-283 (302) | alignment | ||
Range on Protein: 1041-1228
Range on HMM: 97-283/302.0
ESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPATYDSERHFDFYRIKHHEM--NIDNYYTQTILRVLDTQAGEEQTIILIQLPLSNIV-S
| | | .|..| . . ...| ||..|| | | .|. . | .| | .| .. ..... . ... . .|.. . ... .. |
ivpkkstlekhwalieqynvaivvqlcsfvedeekkcaeyysdkvggelkfgrytvktvsvktdleeftdkksfklytveiknekkkkkvkktvdilafs
DELSHTERVGILSAIQEIeKIQrKTGNNPILVHCSDTVSRSGVFCVLYTSIQQMKIEQQVNIYEILYNMRTCKPGLITTPVQykMVYLLLM
| .|.. . | .. . .||||| | |.| . . || . .. .. .|. .|.|. | . . | ..||||.
awpdhGapkeaytaldil.kfc.esykknvlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqdeqq..liylllc
|
|||||||||
subfamily_Sponge-PTP-7_pd | Subfamily Sponge-PTP-7 | 876-939 | 5.1e-11 | 36.8 | In-house | 2-65 (69) | alignment | ||
Range on Protein: 876-939
Range on HMM: 2-65/69.0
LIHCSGGIGVTGMLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEAF
..||| | | || .|.||. . . | ||.. |. || | |. | .| |.| | ||.
vvhcssgtgrtgtfiaimvemarikseklvdifnnvqymrkcrpmmvmneieyifihdalveal
|
|||||||||
subfamily_Sponge-PTP7_pd | Subfamily Sponge-PTP7 | 877-939 | 5.7e-11 | 36.6 | In-house | 2-64 (69) | alignment | ||
Range on Protein: 877-939
Range on HMM: 2-64/69.0
IHCSGGIGVTGMLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLLEAF
.||| | | || .|.||. . . | ||.. |. || | |. |..| |.| | ||.
vhcssGtGrtGtfiaimvemarikseklvdifnnvqymrkcrpmmvmneneymfihdalveal
|
|||||||||
subfamily_hpo-7_pd | Subfamily hpo-7 | 741-941 | 6.2e-11 | 36.7 | In-house | 36-229 (263) | alignment | ||
Range on Protein: 741-941
Range on HMM: 36-229/263.0
KKHQFIAtqgpLPQTLVDFWRLIWQEDICCILMmLSITSDGGIVRCQQYWPDAIGVAAFYGPFKIIVEGINDnkvseERIIK-LSMTSSSSSDNSHKTIH
.| .. | ||. |.. | | . | |. . |...|..|.| . .. . . . . ..| | ..| . .|..
rknlysl....lvqtidkfyqtivqtktevvvm.LcDfneegvekcssyfPlekdekqklanvnvcttkvqs.....dvllktlellstlgeKkkthtvk
HYLFKCWPDHGVPATPTSThsfYEQIKMWLDLpPPVLIHCSGGIG------VTGMLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHY
|| .| |... | . . .. .|. .. .. .||| ||| |. .. || . ||...| . .....||.| |.| | | .
hysykgWiekndpelarei...lnilkvarns.kslvvhcstGiGrsaafsvaElvyqkmirsldttstveldylsLleelrssrkraihtPmqLafsil
VLLEAFYT
..|. ..
mvLdfvln
|
|||||||||
subfamily_eak_pd | Subfamily eak | 681-853 | 7.2e-11 | 36.0 | In-house | 35-196 (332) | alignment | ||
Range on Protein: 681-853
Range on HMM: 35-196/332.0
LQNFGHLFSTEVANCSENKKRNrFKTILPYDNNLLTLRPISSRgdcSHSYINASYIDGYKKKHQFIATQGPLPQTLVDFWRLIWQEDICCILMMLSiTSD
|... .| | .... |. .|| |.||| .|. | . ||||| .. . ...| | . . . ||... .. .|...| .
lddyqrllsisetarleavnrn.vvkivpydrylvrltssqln...rlGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlle.dve
GGIVRCQQYWPDAIGVAAFYGPFKIIVEGINDNKVSEERIIKLSMTsssssDNSHKtIHHYLFKCWPDHGVPA
.. . ..|.|| .| ... ... | | ..||. ...|. ..|| . | . .|
lkleksdkyfpdktreelkfGildverkefvkrniletrllelskG.....nethr.vlhykvfGwtettlpk
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 695-792 | 1.1e-10 | 35.4 | In-house | 45-155 (349) | alignment | ||
Range on Protein: 695-792
Range on HMM: 45-155/349.0
CSENKKRNRFKTILPYDNNLLTLR--PISSR----------GDCSHSYINASYID--GYKKKHQFIATQGPLPQTLVDFWRLIWQEDICCILmMLSITSD
| .||.| ||||. . |. . ||. . . |||| |. .. ....|||| ||| |. ||...| . . .| |. .
GvelfaknrykdilPyehsrvklkkslksskvikastsesdsgklddyinanylkltrisvekkyiatqaPlPstvddfykvillngvklvl.sLnddke
GGIVRCQQYWPD
.. .|..|| .
lslekcdiywqe
|
|||||||||
subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 958-1231 | 1.1e-10 | 35.6 | In-house | 15-279 (303) | alignment | ||
Range on Protein: 958-1231
Range on HMM: 15-279/303.0
RLGKHDEILNMNRYEahykalQVLTVKPNSVLRNFGLSNLPLVRSDLYLPPDEYRVVLNKktEDFIHASYINGYQEaRSFIVAESPTKLTAANFWSMIVK
|. ..| . .| .| .| . | || .| ..|. | . | .| | .|||||.. . . |... | |||.|| ||..
rtldedaniavnefe......kvvsylppsvsknqfvknmdknrfvdvicldhskvklsd..ssyihasyleldss.kkailtqlplshtaadfwqmiie
NKCSVIVMLCDIVEMEVDTCYQYWPATYDSErHFDFYRIKHHEMNIDNYYTQTILRVLDTQAGEEQTIILIQLpLSNIVSDELSHTERVGILSAIQEIEK
.| ....| |.. .| | .|. |. |.. . |.|| |. .... .. . ... .. | ...
qkvkcvlllltdseydklggdsvfprnqdfl.kfeersirvgefkrvelgdgwvlkvlsvsngdyksflhvhh.ykawphnsipsdgspkfvkqiwqlqs
IQRKTG-NNPILVHCSDTVSRSGVFCVLYTSIQQMKIEQQ-VNIYEILYNMRTCKPGLITTPVQYKMVYLLLMRYV
. || ..| . . |.| |... |. .. || ... | |.| . . |. .|| || .|
vlrkysdstptvymslsgcgragtfalfetahlslhseqasldlvkclenvrngrlhavqnlsqfsvvytllaehv
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 874-936 | 1.6e-10 | 35.2 | In-house | 249-312 (319) | alignment | ||
Range on Protein: 874-936
Range on HMM: 249-312/319.0
PVLIHCSGGIGVTGMLISIMIGIEQgLSTG--GVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLL
|. .||| |.| ||..|. | |.. | . ||. .| .| .| . ..| |||.|.. ||
PlvvhcsdGvGrtGlviasdiairs.leeskrsvdiPqlvssvrrdrasavltkeqyefiykvls
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 872-936 | 1.8e-10 | 35.2 | In-house | 228-292 (297) | alignment | ||
Range on Protein: 872-936
Range on HMM: 228-292/297.0
PPPVLIHCSGGIGVTGMLISIMIGIEQGLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVHYVLL
. ..|.||| |.| .|... .. ... || ||....|.|| ..|| ||..... . |
nayllvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqtleqfellydavl
|
|||||||||
subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 1011-1230 | 2.6e-10 | 34.5 | In-house | 58-275 (312) | alignment | ||
Range on Protein: 1011-1230
Range on HMM: 58-275/312.0
YRVVLNKKTEDFIHASYINGYQEARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPAT---YDSERHfDFYRIKHHEMNID---
| | . .||| ... |.....| . |...|| . . .. |..|| .|| . | .| | | | | |..|
grftlagdenfyihanfvkictkperfvctqgplentcthfwqlalslgstsiillcgfvedgsekcakyisdivgfvdledh.rvyteycteieiggks
-NYYTQTILRVLDTQAGEEQTIILIQLPLSNIVSDELSHTERVGILSAIqeiekiqrKTGNNPILVHCSDTVSRSGVFCVLYTSIQQMKIEQQVNIYEIL
. |. .|.|. .|.| . | | .|||. | ..|.. ||| | |.| .... . | .. .. |. ...
kdkithrvlkvvvkatgqesklnhyqwaswpdhgmpdscdtalrllsav........kkdkkpviahcsagvgrtgtlaliesmiaalrhprkqnvkdsf
YNMRTCKPGLITTPVQYKMVYLLLMRY
.| . . . || .. .. .
vllrkdrarsvrvfpqyvyalrcvlef
|
|||||||||
subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 697-783 | 5.4e-10 | 33.3 | In-house | 36-125 (347) | alignment | ||
Range on Protein: 697-783
Range on HMM: 36-125/347.0
ENKKRNRFKTILPYDNNLLTLRPI---SSRGDCSHSYINASYIDGYKKKHQFIATQGPLPQTLVDFWRLIWQEDICCILMMLSITSDGGI
. ..|| | |. . | | || | ...|||||.| . ....| || |||.|. |||... . .. .. | |
kslsknrskdvklidatrvvlspeksknsraddvetyinashikfdnaskeyiltqyplpdtvrdfwkmvsvtkvtqvvtifepikdeai
|
|||||||||
subfamily_Sponge-PTP3_pd | Subfamily Sponge-PTP3 | 653-750 | 1.5e-09 | 31.9 | In-house | 5-95 (95) | alignment | ||
Range on Protein: 653-750
Range on HMM: 5-95/95.0
VKLSEFADHIeLLNKSNGGKGFKSEFQRLQNFGHLfSTEVANCSENKKRNRFKTILPYDNNLLTLrpiSSRGDcsHSYINASYIDGYKKKHQFIATQG
...| | |. | .|| . | ||. .. . | | .||| |.||| ..| ... | |||| ..||| .| .||.||
ihvsvfhshv.lemhsnsdqefdnefksismtsga.pytvgsseanipknrflnifpydatrvvl...ttkrd..sdyinacfvdgyarkncyiaaqg
|
|||||||||
subfamily_Sponge-PTP-4_pd | Subfamily Sponge-PTP-4 | 727-851 | 1.3e-08 | 29.2 | In-house | 12-126 (130) | alignment | ||
Range on Protein: 727-851
Range on HMM: 12-126/130.0
SHSYINASYIDGYKKKHQFIATQGPLPQTLVDFWRLIWQEDICcILMMLsitsdGGIVRCQQYWPDAIGVAaFYGpFKIIVEGINDNkvsEERIIKLS-M
. |||||.. . ... || || .| .|||... . . .|..| | . ..||||. . .| .||| . . | . || | .
gntyinasfvGllgrtaeylltqhpladtsmdfwkmmleryvn.vlvvl.....gsveeedeywpdsePle.wye.ediivtltdrd...efknikasnl
TSSSSSDNSHKTIHHYLFKCWPDHGV
.| .||... . || |
eiesdlneshqaltmfqisnwpsdgt
|
|||||||||
subfamily_eak_pd | Subfamily eak | 1017-1116 | 1.4e-08 | 28.5 | In-house | 75-171 (332) | alignment | ||
Range on Protein: 1017-1116
Range on HMM: 75-171/332.0
KKTEDFIHASYINGYQEARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPATYDSERHFDFYRIKHHEMnIDNYYTQTilRVLD
. . .| || .. . | .|.. . . || |....| ||.| . ||.... .|.| | .| .. .. | . . .| | |
lnrlGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledvelkleksdkyfpdktreelkfGildverkef.vkrnilet..rlle
|
|||||||||
0038934 | (Phosphotyrosine protein) phosphatases II | 839-932 | 1.5e-08 | 30.0 | In-house | 80-170 (194) | alignment | ||
Range on Protein: 839-932
Range on HMM: 80-170/194.0
HHYLFKCWPDHGVPATPTSTHSFYEQIKMWLDLP--PPVLIHCSGGIGVTGMLISIMIgieqgLSTGGVDVMAIVNKMRSQRMNMIQTEEQYQFVH
.|| .||.|.. . ...|.. .. .|. |..|| .|.| ||.|. . . . | .. . .. .|. | ..|.. .... ..
ieylklpfpddgtvPsleillrfldlvdeflnedpggvvaVHCkaGlgRtGtlvaaYL.....iyrlgmsaeeAialfrekRpgaipnqdyleall
|
|||||||||
subfamily_Cele-PTP-2_pd | Subfamily Cele-PTP-2 | 995-1086 | 5.5e-08 | 24.7 | In-house | 44-135 (327) | alignment | ||
Range on Protein: 995-1086
Range on HMM: 44-135/327.0
SNLPlVRSDLYLPPDEYRVVLNKKTEDFIHASYINgyQEARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEME---VDTCYQYWPATYD
||| | | .| . | || |.|. |. | .|. ..||| .. | .|.|.. ..| || .| || |.|. .
knlp.vnvrlpipirdnrrvlcgsdeeffpgqyvr..megaeyiivqaptkksskliwrvilkdhirilvclchdeqmsgsddgkcytyfptele
|
|||||||||
subfamily_PTEN_pd | Subfamily PTEN | 816-934 | 2.3e-07 | 26.0 | In-house | 60-175 (184) | alignment | ||
Range on Protein: 816-934
Range on HMM: 60-175/184.0
SEERIIKLSMTSSSSSDNSHKTIHHYLFKcwpDHGVPATpTSTHSFYEQIKMWLDLPPP--VLIHCSGGIGVTGMLISIMIgIEQGLSTGGVDVMAIVNK
. .|. | . . .|.. .. ...| |. || | ... |.|..||. . | .|| | | ||.||. . ....| . ..... ..
dhykiynlrserkydskkfdgrvavypfd...Dhnpppl.elleeivediekwleedkknvvvvHCkaGkGRtGvlivayl.lkslllekaeealelfae
MRSQRMNMIQTEEQYQFVHYV
.|.. . .. | .|.|.
aRtknkkgvtiPsqrRYveYy
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 836-937 | 2.6e-07 | 24.7 | In-house | 215-342 (350) | alignment | ||
Range on Protein: 836-937
Range on HMM: 215-342/350.0
KTIHHYLFKCWPDHGVPATPTSTHSFYE-----------QIKMWLDLPPPVLIHCSGGIGVTGMLISIMIGIE---------Q-----GLSTGGVD-VMA
... .| |.| .. | | . | . . . .|.|.||| |.| ||.|... .. . . | .
yvvyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlisi
IVNKMRSQRMNMIQTEEQYQFVHYVLLE
|||..|.||..|.|. .|. |.. ||
ivnelrkqrismvqnldqfifiYeallf
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 1018-1093 | 3.1e-07 | 24.0 | In-house | 88-165 (349) | alignment | ||
Range on Protein: 1018-1093
Range on HMM: 88-165/349.0
KTEDFIHASYING--YQEARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEMEVDTCYQYWPATYDSERHFDF
| .|.| | |.. .. . .| | | .|. .|. |. ... | | | ... |..|| |. . .
klddyinanylkltrisvekkyiatqaPlPstvddfykvillngvklvlsLnddkelslekcdiywqelsysnitvkl
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 1161-1231 | 4.3e-07 | 23.9 | In-house | 244-315 (319) | alignment | ||
Range on Protein: 1161-1231
Range on HMM: 244-315/319.0
KTGNNPILVHCSDTVSRSGVFCVLYTSIQQMKIE-QQVNIYEILYNMRTCKPGLITTPVQYKMVYLLLMRYV
. . |. ||||| | |.|. .|.... . |.| .... .| . . | ||...| | |
resqGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefiykvlseya
|
|||||||||
subfamily_PTPDC1_pd | Subfamily PTPDC1 | 835-932 | 5.4e-07 | 24.2 | In-house | 80-169 (182) | alignment | ||
Range on Protein: 835-932
Range on HMM: 80-169/182.0
HKTIHHYLFkCWPDHGVPAtPTSTHSFYEQIKMWLDLPpPVLIHCSGGIGVTGMLISIMIGIEQGLSTggvdvMAIVNKMRSQRMNMIQTEEQYQFVH
.. | .| | |.|.||.. .. ... |. | .|| | | ||.||. .. . |.. ....||.| . ||| || ..|.
eqgiyvynf.gwkDygvas.leriLdivkvvafalqeg.kvavhChaGlGrtGvliacylvyakrlta.....ekaiklvrskrpksiqtreqvelvk
|
|||||||||
subfamily_Sponge-PTP-7_pd | Subfamily Sponge-PTP-7 | 1168-1223 | 6.6e-07 | 23.6 | In-house | 2-57 (69) | alignment | ||
Range on Protein: 1168-1223
Range on HMM: 2-57/69.0
LVHCSDTVSRSGVFCVLYTSIQQMKIEQQVNIYEILYNMRTCKPGLITTPVQYKMV
.|||| |.| | . . ..| |. |.|.. . || |.| .. ..| ..
vvhcssgtgrtgtfiaimvemarikseklvdifnnvqymrkcrpmmvmneieyifi
|
|||||||||
subfamily_Cele-PTP-12_pd | Subfamily Cele-PTP-12 | 1009-1072 | 1e-06 | 22.5 | In-house | 47-113 (332) | alignment | ||
Range on Protein: 1009-1072
Range on HMM: 47-113/332.0
DEYRVVLNK--KTEDFIHASYINGYQEARSFIVAESPTK-LTAANFWSMIVKNKCSVIVMLCDIVEM
| || | .|| ||...|| . ..|.|..| . | || |. . | |.|... || |
dhsrvelapqdgkddfynaswvdgyskksayifaqapfndhteyvfwrmvserkpsmilvfgdidek
|
|||||||||
subfamily_CDKN3_pd | Subfamily CDKN3 | 837-932 | 1.9e-06 | 21.6 | In-house | 101-189 (202) | alignment | ||
Range on Protein: 837-932
Range on HMM: 101-189/202.0
TIHHYLFkcwPDHGVPAtPTSTHSFYEQIKMWLDLPPPVLIHCSGGIGVTGMLISIMIGI-EQGLSTggVDVMAIVNKMRSQRmnMIQTEEQYQFVH
..||| . .| .|| ..| . |.... |. |.|| ||.| . ..|. .. . .. .. | .. . ... | ||| ||....
ivhhypi...adglvpd.iasclkileelrinlkayrktlvhcygglgrsslviaclllylddtiep..kdaidklrdlkgsr..aiqtvkqynyls
|
|||||||||
PTEN_1 | 838-934 | 1.9e-06 | 22.8 | In-house | 95-188 (196) | alignment | |||
Range on Protein: 838-934
Range on HMM: 95-188/196.0
IHHYLFkCWPDHGVPATPTSTHsFYEQIKMWLD-LPP--PVLIHCSGGIGVTG-MLISIMIGIEQglsTGGVDVMAIVNKMRSQRMNMiqTEEQYQFVHY
. .. | ..|||.| . . .... || .|. ||.|| .|.| .| .... .. .. . ...|...|.... . .| ....|
veylhf.pieDhgapslselfd.icksfiewllsdpngnvVlVHCkaGlgRsGtvvaayLmykgk...ltadeAlelvrekRppgapn..spsqerlley
V
.
f
|
|||||||||
subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 984-1084 | 3.3e-06 | 20.9 | In-house | 84-181 (244) | alignment | ||
Range on Protein: 984-1084
Range on HMM: 84-181/244.0
KPNSVLRNFGLSNLPLVRSDLYLPPDEYRVVLNKKT--EDFIHASYINGYQEARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIVEmEvDtcyQYW
|. . | .| | || | || |.| . . .| ||.. . .|... | |. .|| |... . |.|.| . | | | .||
dpsvmkdafnpnnswknregaglpfdfnrvplskgsmgntyinasfvgclgrtaeyiltqhpladtsmdfwkmmlerhvnvlvvlgsvee.e.d...eyw
PAT
| .
pds
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 1155-1230 | 3.6e-06 | 21.0 | In-house | 218-294 (297) | alignment | ||
Range on Protein: 1155-1230
Range on HMM: 218-294/297.0
IEKIQRK-TGNNPILVHCSDTVSRSGVFCVLYTSIQQMKIEQQVNIYEILYNMRTCKPGLITTPVQYKMVYLLLMRY
.| .. . | ..||||| | |||| . ..... .. .. || .| .. |. | |....| . ..
leslraemprnayllvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqtleqfellydavlkk
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 656-738 | 3.7e-06 | 20.5 | In-house | 9-85 (440) | alignment | ||
Range on Protein: 656-738
Range on HMM: 9-85/440.0
SEFADHIEllnKSNGGKGFKSEFQRLQnFGHLFSTEVANCSENKKRNRFKTILPYDNNLLTLRPIssRGDCSHSYINASYIDG
..|||... .. . |. |. | | ...|. .|| .||.. || ||.. . | . .| . |||||||.|
adfadyvq...nnrrsrafedewsllp.sglsqpsdiaslpnnkvknryrnilaydhsrvmleev..kgvpdsdyinasying
|
|||||||||
subfamily_Sponge-PTP7_pd | Subfamily Sponge-PTP7 | 1169-1223 | 4e-06 | 21.1 | In-house | 2-56 (69) | alignment | ||
Range on Protein: 1169-1223
Range on HMM: 2-56/69.0
VHCSDTVSRSGVFCVLYTSIQQMKIEQQVNIYEILYNMRTCKPGLITTPVQYKMV
|||| |.| | . . ..| |. |.|.. . || |.| .. .| ..
vhcssGtGrtGtfiaimvemarikseklvdifnnvqymrkcrpmmvmneneymfi
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 1019-1088 | 5.4e-06 | 20.0 | In-house | 220-286 (440) | alignment | ||
Range on Protein: 1019-1088
Range on HMM: 220-286/440.0
TEDFIHASYINGYQEARSFIVAESPTKLTAANFWSMIVKNKCSVIVMLCDIvemEVDTCYQYWPATYDSE
|. ..|| .|| .. | | .|| .. . | |.|| .. . || ||| |
tdksplqqefegyskknafiatqmpldstvldfwrlvhdyristiimlnql...ndktcsiywpvntrsv
|
|||||||||
subfamily_DSP1_pd | Subfamily DSP1 | 1150-1195 | 8.2e-06 | 20.0 | In-house | 83-127 (163) | alignment | ||
Range on Protein: 1150-1195
Range on HMM: 83-127/163.0
SAIQEIEKIQRKTGNnpILVHCSDTVSRSGVFCVLYT-SIQQMKIEQ
.|. |.....| | .|.|| .||| .|..| . .....|.
eviefidevkkknGk..vlihCqaGisRsstlclaylmktkrvslee
|
|||||||||
0038934 | (Phosphotyrosine protein) phosphatases II | 1147-1225 | 9.1e-06 | 20.9 | In-house | 98-171 (194) | alignment | ||
Range on Protein: 1147-1225
Range on HMM: 98-171/194.0
GILSAIQEIEKIQRKTGNNPILVHCSDTVSRSGVFCVLYTsiqqmKIEQQVNIYEILYNMRTCKPGLITTPVQYKMVYL
.|. .. .... .. .. ..||| ..|.|.... | .. . | .. .| ..|| | .. ......
illrfldlvdeflnedpggvvaVHCkaGlgRtGtlvaaYL.....iyrlgmsaeeAialfrekRpgaipnqdyleallk
|