Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
| Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
|---|---|---|---|---|---|---|---|---|---|
| subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 1095-1311 | 2.9e-124 | 408.7 | In-house | 69-287 (287) | alignment | ||
Range on Protein: 1095-1311
Range on HMM: 69-287/287.0
EHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSNRK---LGEYNISLLNEEiHNAGYIERKIEVTNDN
|||||||||||.||||||||||||||||||||||||.|||||||||||||||. |..|||||||.. | ||||||.||||| .||||||||.||.|.|
ehpdyinavfidgykekkafiiaesPmfntarnfWkliddrnvtaivmlcqekendeevcyqyWpeeksvvlGeyniellnee.vnagyierklevknkn
KAGDKQQVKQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKRGNTSIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQY
|||||||||||||||||||||.|.||||||||||||.|||||||||||.|||||||||..|||||||||||||||||||||||||||||||||||||.||
kagdkqqvkqyqitnWdstgkvtepqtillvieemyktqrkrgntsivvhCsdtvGrsamfcaaattinkckteGviDvfqvlksqriqkpgsvqtveqy
QGIFQIVLTYLDSFETYSNF
..|..|||.|||||||||.|
kfindivleyldsfetysdf
|
|||||||||
| subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 1097-1309 | 4.9e-112 | 368.5 | In-house | 72-290 (290) | alignment | ||
Range on Protein: 1097-1309
Range on HMM: 72-290/290.0
P----DYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSNR---KLGEYNISLLNEEIHNaGYIERKIEVTN
. .||||..|.||||||..|....|..||...|||.|....||.||||..........|.|||... ..||..| |||||..| .|||||.||.|
kDCtneyinAcyikgykekkqyiatqgpvsntlvdFWkliwqekvtiivmltniieegkvkCqqYWpdsdtkaygefsikllneetln.eyierklevkn
DNKAGDKQQVKQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKRGNTSIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQ
.|.||.||.|.||||||||||||.||||||||||||||.|||||||||||.|||||||||.|||||||||||||||||||||||||||||||||||||||
knsagakqsvtqyqitnwdstgkvtnpqtillvieemyktqrkrgntsivvHCSdtvgrsavfcaaattinkcktegvidvfqvlksqRiqkpgsvqtvq
QYQGIFQIVLTYLDSFETYS
||||||||||||||||||||
qyqgifqivltyldsfetys
|
|||||||||
| subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 942-1094 | 4.6e-88 | 289.8 | In-house | 1-153 (290) | alignment | ||
Range on Protein: 942-1094
Range on HMM: 1-153/290.0
MIPVDKFGEFVANGHAKGNEGFRNQFGMLDSGESDHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMPGHKDCTNEYINACFIKDYSNQYQYIATQGPV
.|||||||||||||||||||||||||.|||||||.||||||||.|||||||||||||||||||||||..|||||||||||||.||.|....|||||||||
lipvdkfgefvanghakgnegfrnqfkmldsgesehtvtvgltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgykekkqyiatqgpv
SNTLVDFWQLIWQEKSTIIVMITNIIEEGKVKCQQYWPNSDTKDYGPFSVTLR
||||||||.||||||.|||||.||||||||||||||||.||||.||.||..|
sntlvdFWkliwqekvtiivmltniieegkvkCqqYWpdsdtkaygefsikll
|
|||||||||
| subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 15-159 | 7.3e-71 | 233.4 | In-house | 140-286 (290) | alignment | ||
Range on Protein: 15-159
Range on HMM: 140-286/290.0
TPSGMiLGEYNIILLNEETFNGYIERKFEVKNNNT-GATQSVTQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAAT
... . .||..| ||||||.|.|||||.||||.|. ||.||||||||||||||||.||||||||||||||.||||||||||||||||||||||.||||||
sdtka.ygefsikllneetlneyierklevknknsagakqsvtqyqitnwdstgkvtnpqtillvieemyktqrkrgntsivvHCSdtvgrsavfcaaat
TINKCKTEGVIDVFQVLKSQRIQKPGSVQTVDR--IIPDYFMIYASQF
|||||||||||||||||||||||||||||||.. .| . .. | ..|
tinkcktegvidvfqvlksqRiqkpgsvqtvqqyqgifqivltyldsf
|
|||||||||
| subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 18-148 | 6.8e-70 | 230.3 | In-house | 137-270 (287) | alignment | ||
Range on Protein: 18-148
Range on HMM: 137-270/287.0
GMILGEYNIILLNEETFNGYIERKFEVKNNN-TGATQSVTQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTIN
..|||||| |||||. .||||||.||||.| .|..|.|.||||||||||||.|.||||||||||||.||||||||||||||||||||||||||||||||
svvlGeyniellneevnagyierklevknknkagdkqqvkqyqitnWdstgkvtepqtillvieemyktqrkrgntsivvhCsdtvGrsamfcaaattin
KCKTEGVIDVFQVLKSQRIQKPGSVQTVDR--II
||||||||||||||||||||||||||||.. |
kckteGviDvfqvlksqriqkpgsvqtveqykfi
|
|||||||||
| subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 1097-1307 | 6.3e-66 | 217.6 | In-house | 74-288 (305) | alignment | ||
Range on Protein: 1097-1307
Range on HMM: 74-288/305.0
PDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSNR-----KLGEYNISLLNEEiHNAGYIERKIEVTNDN
||||| ...|||.||..|.| .|. || ..||..| . |. ||||.. ..... |.||| .. ..||... | .|. . ..|||||.......
sdyinasyvdgykrkkkyivaqgPlkntvadfWrliveekvstivmltklveggkdkCrqYWpesktekkefgefsvelksek.tasdyieRklkisied
KAGDKQQVKQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKRGNTSIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQY
. ....| |||.|.| | . . ..| .|... ..|.| ......|||..|||.|||.| ....|.|.|.|||.||| | .... ||| .||
edkesrtvlqyqltdWPdhGvpqfatsllslikrvqkdqkkdkgvpllVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkmvqtldqY
QGIFQIVLTYLDSFET
. ..... .. ...|
vflhdaldelitcgdt
|
|||||||||
| subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 1098-1310 | 2.9e-61 | 201.8 | In-house | 71-301 (301) | alignment | ||
Range on Protein: 1098-1310
Range on HMM: 71-301/301.0
DYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSN-----RKLGEYNISLLNEE----------------IH
.|||| .|.||.|||.||.|..|| .| ..||..| . ...|||....... .. |.|||.| . |. .. | ||
eyinasyidgysekkkfiaaqgpmkktlvdfWrliwqekpvsivmvtnlkegtkskceqywpnseaeseefgpftvtlvneqvyPdfvirqlnvkiqdgs
NAGYIERKIEVTNDNkagDKQQVKQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKRGNTSIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKS
| ||||||..|..|. . ..| |.|.|.| | . .|.|.| ||... .|.| | .|.||||||.||||.|. .. || |||.||||| |.
nngyierkfkvksdk...sswdvlqlqvtdWpqdGvvreprtvLqviddvihrqqkigggpvvVHCSdtVsrsGvYcsvsiglEQckaegVVdvfqvtka
QRIQKPGSVQTVQQYQGIFQIVLTYLDSFETYSN
| .||| |.| .|| |.... .|| .||.|
vrrskpgaVtTLeqytsiydvidmylqlnstyan
|
|||||||||
| subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 942-1095 | 2.6e-60 | 198.8 | In-house | 1-149 (287) | alignment | ||
Range on Protein: 942-1095
Range on HMM: 1-149/287.0
MIPVDKFGEFVANGHAKGNEGFRNQFGMLDS-GESDHTVTVGLTPSNKLLNRFANIVVYDDNRITLRpmpghkDCTNEYINACFIKDYSNQYQYIATQGP
.|||.|||||||.|||||||||.||| .|.. ..... ||......|| .||...|.|.|..|. |. .. ..||||.||. |......|....|
lipvekfgefvakghakgnegfknqftvleqvtqredevthniasqnkdknRltqilvpdnyrvllk......gehpdyinavfidgykekkafiiaesP
VSNTLVDFWQLIWQEKSTIIVMITNIIEEGKVKCQQYWPNSDTKDYGPFSVTLRE
..||...||.||.... |.|||... |. . .| ||||.... .|.....| .
mfntarnfWkliddrnvtaivmlcqekendeevcyqyWpeeksvvlGeynielln
|
|||||||||
| 0050432 | (Phosphotyrosine protein) phosphatases II | 1091-1309 | 2.3e-59 | 196.6 | In-house | 85-306 (308) | alignment | ||
Range on Protein: 1091-1309
Range on HMM: 85-306/308.0
VTLREHPDYINAVFINGY--KEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYW------SNRKLGEYNISLLNEEIhNAGYIE
| | |. ||||| ...|| | ...||.. .|. || .||.|. . ||. ||||... |..| |.||| . .. | . . ||.||. ...|.
VkldegsdYInAsyvdgyssklprkfIatqgPlpntvedFwrmvweqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseev.lddytv
RKIEVTNDNKAgDKQQVKQYQITNWDSTGKLTNPQTILLVIEEMYRTQrkrGNTSIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRIQKP
|..|.|| .. . .|.... ||| | ..|. .| .|.. ... .. ||.|||. |||.|.|.|. . .. ..|| .|||...| | |.|
rtleltnlgdg.esrtvthfhytnWpdhgvPpspeilldflelvrksl...pggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRp
GSVQTVQQYQGIFQIVLTYLDSFETYS
|.|||..||. .....| || ...|.
gmvqtpeqylflyralleylklkltkl
|
|||||||||
| subfamily_PTPRD_pd | Subfamily PTPRD | 1095-1308 | 1.2e-58 | 194.1 | In-house | 74-287 (564) | alignment | ||
Range on Protein: 1095-1308
Range on HMM: 74-287/564.0
EHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSNR---KLGEYNISLLNEEiHNAGYIERKIEVtNDN
| ||||| ||.||...||.| . |. .| ..||.|. ..|.. |||| . . .... | .|| .. . ||. ..| .|| . | |. |.... ...
egsDYINAsfidgyrkrkayIAtqgPlaetiedFWRmvweqnsstiVmltkleEkgkvkchkYWPekgtetygeltVtleeee.eladyeirtfkl.kkk
KAGDKQQVKQYQITNWDSTGKLTNPQTILLVIEEMYRTQrKRGNTSIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQY
| ....|.|.. |.| ..| ......| .|... ... .... ||.||| |||.|.|.. ... |.|...|..|..| | |.. ||| .||
kssesreVrqFhFtsWPdhgvpesatslLdlirkvraln.epdagPivVhCSaGVGRTGtfividamlerikeektvDiyqyvkalrkqRnamVqteeQY
QGIFQIVLTYLDSFETY
. |....| .|....|
iFiheailealacgnte
|
|||||||||
| subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 1095-1308 | 1.8e-58 | 193.1 | In-house | 82-296 (298) | alignment | ||
Range on Protein: 1095-1308
Range on HMM: 82-296/298.0
EHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSN---RKLGEYNISLLNEEiHNAGYIERKIEVTNDN
|. |||||.|...||...|||... |. .| .||.|. ......|||| . . .. . .|| . .. || ..|||..| . | .| ||..|.. .
eesdYiNAsflhaykgrnafiatqaPltetvedFWrmvteedigtiVmltnleeldktkyhkywPdegketygeitvsllske.efadlivrklkvskkk
KAgDKQQVKQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKRGNTSIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQY
.. ....|.| . |.| . | .| ...| ..... ..|.. ||......||. ||||| |.| . ... |.| |.|||||.| |...||.||| .||
ee.kerevrqlhftsWpdkgvpenatsvldllrkvrasqqqagnkpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqteeqY
QGIFQIVLTYLDSFETY
|...|| .||||...
vfiyeavlealdsfnde
|
|||||||||
| 0046845 | (Phosphotyrosine protein) phosphatases II | 1095-1310 | 8.3e-58 | 191.4 | In-house | 55-282 (284) | alignment | ||
Range on Protein: 1095-1310
Range on HMM: 55-282/284.0
EHPDYINAVFINGY-----KEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSNR----KLGEYNISLLNEEIhNAGYIERKI
|. ||||| ...|| . ||.||.. |. || .||.|. . ||. ||||... |..| |.|||.. ..|.. . ||.||. . .|. |..
edsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqnvrvIVmltelvengrekcaqYwplegevltygdftvtllseev.kddytvrtl
EVTNDNKAGDKQQVKQYQITNWDSTGKLTNPQTILLVIEEMYRTQRK-RGNTSIVIHCSDTVGRSGVFCAAATTINKCKTEG---VIDVFQVLKSQRIQK
|.|| . | .|.....|.| | ..|. .| .... . ... |. ||.|||. |||.|.|.|. . .. ..|| ..||....| | |.
eltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrellenlpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqR
PGSVQTVQQYQGIFQIVLTYLDSFETYSN
||.|||..||. .....| || .. |. .
pgmvqtleqyrfvyealleylklkltlle
|
|||||||||
| subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 1096-1310 | 1.6e-56 | 186.7 | In-house | 73-288 (318) | alignment | ||
Range on Protein: 1096-1310
Range on HMM: 73-288/318.0
HPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSNRKLGEYNIS--LLNEEIHNAGYIERKIEVTNdNKA
||||| .|.||..|||.| | .|. .| ..||.|. ..| . |||| ||. . .. . .|| ... .|. |.||.. . |. |...||. ..
gsDyinanyidGyrrkkayiaaqaPlpetieDfWrmvWeqnsavivmltqeeergkakvhryWPskgsrsygklvvelkeevelsdyvlrefkvtr.tee
GDKQQVKQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKRGNTSIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQG
...||.||..|.| .| .... ..| .. . ..|.| |.. ||.||| ||| |||.| . ... | |...||||. | | |.. ||| .||.
eesrqvrqyhytsWpdegvpesgaslldlvrqvskaqqksgagpivvhCsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqtedqyef
IFQIVLTYLDSFETYSN
|....| .| |..|. .
iydvllealasgdtevd
|
|||||||||
| 0036941 | (Phosphotyrosine protein) phosphatases II | 1095-1308 | 3.1e-56 | 186.2 | In-house | 61-283 (297) | alignment | ||
Range on Protein: 1095-1308
Range on HMM: 61-283/297.0
EHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSNR-----KLGEYNISLLNEEIH-NAGYIERKIEVT
|. ||||| ...||. |..||... |. || .||.|. . ||| ||||... .. | |.|||.. . |.. . ||..|.. ...|. |..|||
egsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqnvtvIvmltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevt
NDnKAGDKQQVKQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKR-GNTSIVIHCSDTVGRSGVFCAAATTINKCK---TEGVIDVFQVLKSQRIQKPGS
. . |.. .|.....|.|. | ..|...| ||.. . ... ... ...|||. |||||.|.|| . .. . .|| .|.....|. | |.||.
dt.gngesrtvthfhytgwpdhgvpespaslldfielvrkvlkllpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpga
VQTVQQYQGIFQIVLTYLDSFETY
|||..||. . ...| .| ...|.
vqtleqyrflyeallellkkkltk
|
|||||||||
| 0051299 | (Phosphotyrosine protein) phosphatases II | 1096-1302 | 7.8e-56 | 185.0 | In-house | 76-286 (288) | alignment | ||
Range on Protein: 1096-1302
Range on HMM: 76-286/288.0
HPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWS---NRKLGEYNISLLNEEIhNAGYIERKIEVTNDN-
. ||||| .|.||. |..||... |. || .||.|. . ||. ||||... ...| |.|||. ..|.. . ||.||. ...|. |..|||| .
gsdYinAsyidgynlkrkfIatqgPlpntvedFWrmvweqnvrvIvmltklvelgrekcaqYwplggsltygditvtllseev.lddytvrtlevtnldl
--KAGDKQQVKQYQITNWDSTGKLTNPQTILLVIEEMYRTQRkRGNTSIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQ
. | ...|.... ||| | ..|. .| ...... .. |. .|.|||. |||.|.|.|. . .. ..||..||....| | |.||.|||..
ldgdgesrtvthfhytnwpdhgvpdspellldflrlvrkala.sgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpe
QYQGIFQIVLTYL
||. .....| ||
qyrfvyealleyl
|
|||||||||
| 0047943 | (Phosphotyrosine protein) phosphatases II | 1096-1302 | 3.9e-55 | 182.6 | In-house | 61-272 (273) | alignment | ||
Range on Protein: 1096-1302
Range on HMM: 61-272/273.0
HPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWS------NRKLGEYNISLLNEEIhNAGYIERKIEVTN
. ||||| ...||. |..||... |. || .||.|. . ||. ||||... ...| |.|||. . |.. . ||.||. ...|. |..|.||
gsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvweqnvrviVmLtelvelgrekcaqYwpleggelsltygkftvtllseet.kddytvrtleltn
DNKAGdKQQVKQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKR-GNTSIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTV
. . .|.... |.| | .... .| ||.. ..... .|. .|.|||. |||.|.|.|. . .. ..|| .||....| | |.||.|||.
lgtge.srtvthfhytgwpdhgvppslesllefielvrkalealpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtp
QQYQGIFQIVLTYL
.||. . ...| ||
eqyrflyealleyl
|
|||||||||
| Y_phosphatase | Protein-tyrosine phosphatase | 1095-1299 | 1.7e-54 | 180.1 | Pfam-A | 25-234 (235) | alignment | ||
Range on Protein: 1095-1299
Range on HMM: 25-234/235.0
EHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWS-----NRKLGEYNISLL-NEEIHNAGYIERKIEVT
.. ||||| ...||||||.||... |. .| ||.|. ...|..||||........| | |||. . |.... | .|. ....|. ||.|..
gpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesltygdikvelkekekedekeytlrklelk
NDNKAGDKQQVKQYQITNWDSTGKLTNPQTILLVIEEMYRTQrKRGNTSIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTV
.... .|..|||...||| | ..|. .| .|... ... . ....|.|||. |||.|.|.|. . ......|. .||.|..|. | |.||.||..
kkkeesekrevkqlhytnWpdhgvpespkslldlirkveksk.eaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmvqsl
QQYQGIFQIVL
.||. . ...|
eqYiflykail
|
|||||||||
| Y_phosphatase | Protein-tyrosine phosphatase | 1095-1299 | 1.7e-54 | 180.1 | In-house | 25-234 (235) | alignment | ||
Range on Protein: 1095-1299
Range on HMM: 25-234/235.0
EHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWS-----NRKLGEYNISLL-NEEIHNAGYIERKIEVT
.. ||||| ...||||||.||... |. .| ||.|. ...|..||||........| | |||. . |.... | .|. ....|. ||.|..
gpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesltygdikvelkekekedekeytlrklelk
NDNKAGDKQQVKQYQITNWDSTGKLTNPQTILLVIEEMYRTQrKRGNTSIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTV
.... .|..|||...||| | ..|. .| .|... ... . ....|.|||. |||.|.|.|. . ......|. .||.|..|. | |.||.||..
kkkeesekrevkqlhytnWpdhgvpespkslldlirkveksk.eaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmvqsl
QQYQGIFQIVL
.||. . ...|
eqYiflykail
|
|||||||||
| subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 1095-1310 | 2.2e-54 | 179.3 | In-house | 35-250 (250) | alignment | ||
Range on Protein: 1095-1310
Range on HMM: 35-250/250.0
EHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEvCYQYWS---NRKLGEYNISLLNEEIHnAGYIERKIEVTNDN
.. |||||.|..||.|.||||.. .|. .| .||.|. ......|||| . . .... . ||| .| |. .|||..|.. | |. ||. ... .
kesdyinasflhgyderkafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqywPvekaekyGdvtvsllskeef.adytkrklklskak
KAgDKQQVKQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKRGNTSIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQY
|| |...|.|.. ..| | . ...| ..... ..|.. ||. ....|| ||||| |.| . ... |.| |.|||.|.| |...|..|.. .||
ka.derivrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidavlerlkkekvvdvfkvikvlrkdrphavesleqy
QGIFQIVLTYLDSFETYSN
...|.| .|||.| |..
vfvyeiilkaldsvedyar
|
|||||||||
| 0040438 | (Phosphotyrosine protein) phosphatases II | 1096-1308 | 8.4e-54 | 178.3 | In-house | 70-282 (317) | alignment | ||
Range on Protein: 1096-1308
Range on HMM: 70-282/317.0
HPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSN---RKLGEYNISLLNEEIhNAGYIERKIEVTNDnK
. ||||| ...|...|..||.. .|. || .||.|. . .|| ||||... ...| |.|||.. . |.. . ||.|| .||.. |..||... .
dsdYInAsyvdgpnlkrkfIatqgPlpntvedFwrmvweqgvtvivmLteleelgrekcaqYwplgetltygdftvtllseee.lagitlrtlevedl.g
AGDKQQVKQYQITNWDSTGKLTNPQTILLVIEEMYRTQRkRGNTSIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQ
... .|.... |.|. | .|...| .|.. . .. .... ...|||. |||.|.|.|| . .. ...|| .||....| | |.||.||| .||.
dsesrtvthfhytgWpdhgvppspdllldfleavreale.dpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyr
GIFQIVLTYLDSFETY
. ...| || ..|.
flydalleylkrkltl
|
|||||||||
| 0045450 | (Phosphotyrosine protein) phosphatases II | 1095-1302 | 1.8e-53 | 177.6 | In-house | 82-304 (307) | alignment | ||
Range on Protein: 1095-1302
Range on HMM: 82-304/307.0
EHPDYINAVFI--------NGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSNR----KLGEYNISLLNEEIhNAGYIE
|. ||||| .. .||. |..||.. .|. .| .||.|. . .||.||||... ...| |.|||.. |.. . ||.||. .||.
edsdYiNAsyvrvpllllldgydlkrkfIatqgPlpetvedFwrmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseeh.ldgytv
RKIEVTNDNKAGDKQQVKQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKR-GNTSIVIHCSDTVGRSGVFCAAATTINKCKTEGV---IDVFQVLKSQR
|..|||. .. | .|.... |.| .| ......| |||. . ... ... ...|||. |||.|.|.|| . . ..||. .|.....| |
rtlevtdldgtgesrtvthfhytgwpdhgvppsfeelldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllr
IQKPGSVQTVQQYQGIFQIVLTYL
|.||.||. .||. . ...| .|
eqRpgavqnpeqyrflyeallell
|
|||||||||
| DSPc_SM00195 | 1096-1302 | 2e-53 | 176.8 | In-house | 53-262 (263) | alignment | |||
Range on Protein: 1096-1302
Range on HMM: 53-262/263.0
HPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSNR-----KLGEYNISLLNEEIHNAGYIERKIEVTND
. ||||| .|.|...||..|.. |. .| . ||.|. ...|. ||||..|..|..| |..|| . . |.... | ..|.... .| |..|.|..
gsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltke
NKaGDKQQVKQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKRgNTSIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQ
.| ....|.|||..|| | ... .| ...... .... .. ||.|||. |||.|.|... . ..|...| .|.|...|. | |.||.||| .|
gk.eetrkvtqyqyknWpdhgvpdstksvlellravkksksts.sgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleq
YQGIFQIVLTYL
|. | ...| |.
Ylfiyeaileyi
|
|||||||||
| PTPc_SM00194 | 1096-1302 | 2e-53 | 176.8 | In-house | 53-262 (263) | alignment | |||
Range on Protein: 1096-1302
Range on HMM: 53-262/263.0
HPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSNR-----KLGEYNISLLNEEIHNAGYIERKIEVTND
. ||||| .|.|...||..|.. |. .| . ||.|. ...|. ||||..|..|..| |..|| . . |.... | ..|.... .| |..|.|..
gsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltke
NKaGDKQQVKQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKRgNTSIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQ
.| ....|.|||..|| | ... .| ...... .... .. ||.|||. |||.|.|... . ..|...| .|.|...|. | |.||.||| .|
gk.eetrkvtqyqyknWpdhgvpdstksvlellravkksksts.sgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleq
YQGIFQIVLTYL
|. | ...| |.
Ylfiyeaileyi
|
|||||||||
| subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 1096-1307 | 9e-52 | 171.1 | In-house | 75-288 (319) | alignment | ||
Range on Protein: 1096-1307
Range on HMM: 75-288/319.0
HPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSNRKLGEYNISLL--NEEIHNAGYIERKIEVTNDNKA
||||| ||.||.|...|| . .|. || .||.|. .... .|||.. . . . . .||.. . || .. .|| . ..|| ||... . .
gsdyinasfidgyqerekfiatqaPlentiedfWrmvWeeessivvmltklveklkvklkkywpeenfeeyGrlivtleeeeeledyiirklklnkksse
GDKQQVKQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKRGNTSIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQG
. .||..| |.| . .. ...| ..... ....| . ||.|||. ||| | |.. .... | |||.|||.. . |.|.. ||. .||.
vetRevkhfqyteWpdhdvPekatslldllkrirksrektqsgPivvhCsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeqYkf
IFQIVLTYLDSFET
|....| ......|
iyealleaveagdt
|
|||||||||
| subfamily_PTPRD_pd | Subfamily PTPRD | 942-1095 | 7.4e-51 | 168.4 | In-house | 4-154 (564) | alignment | ||
Range on Protein: 942-1095
Range on HMM: 4-154/564.0
MIPVDKFGEFVANGHAKGNEGFRNQFGMLDSGeSDHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMPGHKDCtnEYINACFIKDYSNQYQYIATQGPV
|||... |.||. .|... | ... ...| . .|... | || ||.|||| || .|. |....|.... .|||| ||. | .. .|||||||.
pipvaelkehvaklkansdlkfeeeykkieeg.qqftweaankpaNkaKNRyanivaYdhsRVvLskvegdegs..DYINAsfidgyrkrkayIAtqgPl
SNTLVDFWQLIWQEKSTIIVMITNIIEEGKVKCQQYWPNSDTKDYGPFSVTLRE
..|. |||...|...|..|||.|.. |.|||||..|||...|. || . ||| |
aetiedFWRmvweqnsstiVmltkleEkgkvkchkYWPekgtetygeltVtlee
|
|||||||||
| 0039614 | (Phosphotyrosine protein) phosphatases II | 1096-1306 | 1e-50 | 168.3 | In-house | 84-293 (297) | alignment | ||
Range on Protein: 1096-1306
Range on HMM: 84-293/297.0
HPDYINAVFINGYKE-KKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQeVCYQYWSNR--KLGEYNISLLNEEIhNAGYIERKIEVTNdnk
. ||||| ...||. ...||.. |. .| .||.|. . .||.||||.... ... |.|||... . |.. . ||..| ..||. |..||||
dsdYinAsyvdgydlltrkfIatqgPlpetvedFwrmvweqgvtvivmLtklvelgr.kcaqywpeeggtygdftvtllkveh.ldgytvrtlevtn...
AGDKQQVKQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKR-GNTSIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQY
| .|...| |.| | .....| ..|.. . ... ... ...|||. |||.|.|.|| . .. ...|| .||....| | |.||.||| .||
ngesrtvthfqytgwpdhgvppslellleflelvrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqy
QGIFQIVLTYLDSFE
. .....| .| .
rflydallellkrkl
|
|||||||||
| subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 1095-1300 | 1.2e-50 | 167.0 | In-house | 55-264 (283) | alignment | ||
Range on Protein: 1095-1300
Range on HMM: 55-264/283.0
EHPDYINAVFIN---GYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSNR---KLGEYNISLLNEEIHNaGYIERKIEVT
| .|||||||| ||..| .||| ||. .| ..||||. |...|||||| . .... | ||| .| . ||. ..| .| .| .| ... .
esrdyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekitaivmltklqedlrikCsqyWPkrGsedyGeftvtlrkettsn.sfiikelllr
NDNKAGDKQQVKQYQITNWDSTGKLTNPQTiLLVIEEMYRTQRKRGNTSIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTV
... | .. . ||. .| . |. . . |. .. . |.. .. ||.||| ..||..||.||...... .|| |.|||.|.| | |... |||
vnssakstlllahyqvidWleygeqaiins.lvkfnkvislqteskkgPivvhCstgiGrtavfiaasasvkdaltesvvdvfavvkimreqrmmavqtl
QQYQGIFQIVLT
.||. . ..||
dqyklvhelvle
|
|||||||||
| 0043336 | (Phosphotyrosine protein) phosphatases II | 1096-1302 | 1.1e-49 | 164.7 | In-house | 72-277 (278) | alignment | ||
Range on Protein: 1096-1302
Range on HMM: 72-277/278.0
HPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSnR---KLGEYNISLLNEEIhNAGYIERKIEVTNdNK
. ||||| ...||. ...||.. |. .| .||.|. . .|| ||||... .... |.|||. . . |.. . ||.|| ...|. |..|||| ..
dsdYinAsyvdgynvprkfiatqgPlpetvedFwrmvwelgvttivmLtelvelgrvkcaqYwp.ggsltygdftvtllkeeh.lddytvrtlevtn.lg
AGDKQQVKQYQITNWDSTGKLTNPQTILLVIEEMYRTQRkRGNTSIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQ
| ...| .|. ..| | ......| .... . .. |. ...|||. |||.|.|.|. . .. ..|| .|.....| | |.||.||| .||.
dgesrtvthyhylgwpdhgvpeslsllldflkavreale.dsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyr
GIFQIVLTYL
.....| ||
flyealleyl
|
|||||||||
| subfamily_Ptp69D_pd | Subfamily Ptp69D | 1092-1305 | 1e-48 | 161.1 | In-house | 71-289 (307) | alignment | ||
Range on Protein: 1092-1305
Range on HMM: 71-289/307.0
TLREHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWS---NRKLGEYNISLLNEEIHNaGYIERKIEVT
. .|. ||||| ||.|||||| ||.| |. .|. .||.|| . .|| |||| ... |.. | .||. . . |. .. | .|| |. ||.|...|.
ngkedsdYinasfikgykekkkfiaaqdPveatigDfWRmiaeqevtlivmlsnlteknrkkcakYWpiedevqygdilvklvseekhs.dyiiReldvs
NDNKAG----DKQQVKQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKRgNTSIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGS
. .. . |...| ||. |.|. . ....| .||... ... .. ||.||| |||||.| | . ....|.| .|.|.. | | |..
kkkeesgevedsrkvvqyhytgWkDskvPevargllklieqvrelykln.rsPivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnll
VQTVQQYQGIFQIVLTYLDSF
|| .||. ... .| | .
vqsleqYvflyralldyssyg
|
|||||||||
| subfamily_PTPRA_pd | Subfamily PTPRA | 1095-1301 | 2.1e-48 | 159.9 | In-house | 84-294 (330) | alignment | ||
Range on Protein: 1095-1301
Range on HMM: 84-294/330.0
EHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSNRKL---GEYNISLLNEEIHnAGYIERKIEVTNDN
|. ||||| ||.|||||. || | | .| .||.|| ... ..|||| . .. ..| |.||| . | |. .... .|.. | ||. |.. .
eesdyinasfidGykekdkfiaaqGPkeetvedfwrmiweqksativmltelkerkeekcaqywPdeGlvtyGnirvevedetvl.vdytvrkflvqqlp
K---AGDKQQVKQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKRGNtSIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTV
. ....|.|. | | | ..|. .| ..... ..... .. .||.||| |||.| |.. . ... |.|...|||...|. | |.| |||
datrekksrlvrqfhftswPdvGvPfepiGmlkllkkvkklnqqsag.pivvhcsaGvGrtGtfivldavlervkaerkvdvfefvkrlrlqrpqmvqtd
QQYQGIFQIVLTY
.||. |....| |
eqyefiykvlley
|
|||||||||
| 0042113 | (Phosphotyrosine protein) phosphatases II | 1096-1302 | 4.6e-47 | 155.9 | In-house | 36-243 (245) | alignment | ||
Range on Protein: 1096-1302
Range on HMM: 36-243/245.0
HPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSNR---KLGEYNISLLNEEIhNAGYIERKIEVTNdNK
. ||||| ...||. .. ||.. |. .| .||.|. . ..|.||||..| .... |.|||... . |.. . ||.||. ...|. |..|||| ..
dsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywplgesltygdftvtllseeh.lddytvrtlevtn.lg
AGDKQQVKQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKRGNTSIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQ
. ...| .|. ..|. | ......| ..|.. . ... .|. ...|||. |||.|.|.|| . .. ..|. .......| | |.||.||| .||.
ddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleqlekelgvsleeavkelrsqRpgavqtpsqyr
GIFQIVLTYL
. ...| .|
flyeallell
|
|||||||||
| 0040439 | (Phosphotyrosine protein) phosphatases II | 1097-1302 | 1.1e-46 | 154.8 | In-house | 39-246 (249) | alignment | ||
Range on Protein: 1097-1302
Range on HMM: 39-246/249.0
PDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSN---RKLGEYNISLLNEEIhNAGYIERKIEVTNDnKA
||||| .|.||. |..||.. |. .| .||.|. . ..|.||||... ...| |.|||.. . |.. . ||..|. ...|. |..|.|| .
sdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywplggsleygdftvtllsvev.kddytvrtleltnl.yd
GDKQQVKQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKR-GNTSIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQ
|.. .|...|.|.| .| .....| ||.. ... .. ...|||. |||.|.|.|| . .. ..|. .|.....| | |.||.||. .||.
gesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdleeavkllrsqRpgavqnpeqyr
GIFQIVLTYL
. ...| .|
flyeallell
|
|||||||||
| 0045098 | (Phosphotyrosine protein) phosphatases II | 1098-1303 | 1.2e-46 | 154.7 | In-house | 52-273 (278) | alignment | ||
Range on Protein: 1098-1303
Range on HMM: 52-273/278.0
DYINAVFINGYkeKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSN---RKLGEYNISLLNEEIHnAGYIERKIEVTND---N
||||| .|.|| .|.||.. |. .|. .||.|. . ..|.||||... ...| |.||| . |.. . ||.||.. |. |...|||
dYINAsyidgy..pkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaqywpeggsltygdftvtllseevl.ddytlrtllvtnltver
KAGDKQQVKQYQITNWDSTGKLTNP--QTILLVIEEMYRTQR------------KRGNTSIVIHCSDTVGRSGVFCAAATTINKCktEGVIDVFQVLKSQ
. . . |.......|. | ..| . .| ..|.. . .. ... ...||| |||.|...|| . . . ||..|.....|
edlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvlVHCsaGvgRtGtlvaaylmlell..eggvdlleavkel
RIQKPG-SVQTVQQYQGIFQIVLTYLD
| |.|| .||. .||. ... .| .|
rsqRpglavqnleqyrflyefllelll
|
|||||||||
| subfamily_PTPRG_pd | Subfamily PTPRG | 943-1095 | 7.7e-46 | 151.4 | In-house | 1-154 (563) | alignment | ||
Range on Protein: 943-1095
Range on HMM: 1-154/563.0
IPVDKFGEFVANGHAKGNEGFRNQFGMLDS--GESDHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMPGHKDCTnEYINACFIKDYSNQYQYIATQGP
.||..| . ||. ||.|. || ..| | | ..| ... |.|| || ||| || |..|.|.||.|. .|||| .|. | . ..||||||
vpvkefakhvaslhadgdigfseefealqsetiskdldaehsqkpenkrKnRylnivaydrsRvklsplpgkkkkl.DYinAnyidGyqkskafiatqgp
VSNTLVDFWQLIWQEKSTIIVMITNIIEEGKVKCQQYWPNSDTKDYGPFSVTLRE
. .|. |||..||.....|||||||. |.|. ||..|||. ....|| ..||| |
lkdtfddFWrmiWeqnvaiivmitnlvergrrkcdvYWPkdesetygalqvtlie
|
|||||||||
| 0051299 | (Phosphotyrosine protein) phosphatases II | 942-1095 | 9.1e-46 | 152.0 | In-house | 4-155 (288) | alignment | ||
Range on Protein: 942-1095
Range on HMM: 4-155/288.0
MIPVDKFGEFVANGHAKGNEGFRNQFGMLDSGESDHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMPGhkDCTNEYINACFIKDYSNQYQYIATQGPV
|.|... ..| . .|.|. |....| .| | |.|....| | |. ||. .|. ||..|. |....| . .. |||| .|. | .. ..||||||
eisveellklvlkllangltglleefeellsllpdltlsaallpenleknRysdilpydhsRVkLsvldg..vegsdYinAsyidgynlkrkfIatqgPl
SNTLVDFWQLIWQEKSTIIVMITNIIEEGKVKCQQYWPNSDTKDYGPFSVTLRE
.||. |||...|......|||.|...| |..|| ||||..... ||...|||..
pntvedFWrmvweqnvrvIvmltklvelgrekcaqYwplggsltygditvtlls
|
|||||||||
| subfamily_PTPN12_pd | Subfamily PTPN12 | 1095-1302 | 6.3e-45 | 148.3 | In-house | 66-277 (290) | alignment | ||
Range on Protein: 1095-1302
Range on HMM: 66-277/290.0
EHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSNR-----KLGEYNISLLNEEIHNAGYIERKIEVTN
|. ||||| ||.| ..|...| | .|. .| .||.||.. ||. .||.|.| ... | .||... . ||....| .|. . ... | ..|..
egsdYinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCerYWpeegeeelefgefevtleeekavdddflirtLkvea
DnkaGDKQQVKQYQITNWDSTGKLTNPQTILLVIEEMYRTQRkRGNTSIVIHCSDTVGRSGVFCAAATTINKCKTEGV---IDVFQVLKSQRIQKPGSVQ
. .....|.|.. |.| | ......| .||.. ..|. . .. .|.||| ||| |. .| . . |.| . .|||... . | |.. ||
q...kesrkvyqfhYtaWPDhgvPssaksllelielvrelqe.sedaPlvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvq
TVQQYQGIFQIVLTYL
| .||. ... |. ..
tkeqyelvykavaelv
|
|||||||||
| subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 1096-1304 | 9.5e-45 | 147.9 | In-house | 68-278 (281) | alignment | ||
Range on Protein: 1096-1304
Range on HMM: 68-278/281.0
HPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSNRK----LGEYNISLLNEEiHNAGYIERKIEVtnDN
. ||||| |..|||..|..|....|. .. .||.|. ...|.||||. .| .... |..|| . . .|.. .. ..|| ..| |||||... ..
ntDYinanfvpgykgekeyiatqgPvPaslvafWqmvweqkvsaivmvtreieagklkChrYWPddnselkygdvtvkstaee.ekatyierkfkl..er
KAGDKQQVKQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKRGNTSIVIHCSDTVGRSGVFCAAATTINKCKTE-GVIDVFQVLKSQRIQKPGSVQTVQQ
. |....|.| . |.| .| .... .| .|......|. ....||||| |||.|.. | . ......| .|| .|... | .. |||| |
esgetreveqlaytaWPdhGvPattkellefrkevlkltekktkaplvihCsaGvGrtGtyialDrlvkaveaeleeldvkavvaelrkernlmvqtvvq
YQGIFQIVLTYLDS
|. ....|| .||
yefvykavldaldk
|
|||||||||
| subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 950-1095 | 1.7e-43 | 143.7 | In-house | 10-154 (288) | alignment | ||
Range on Protein: 950-1095
Range on HMM: 10-154/288.0
EFVANGHAKGNEGFRNQFGMLDSGESDHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMPghKDCTNEYINACFIKDYSNQYQYIATQGPVSNTLVDFW
. ||. .|....|| ... | . |....||.| . |. ||. ||. || .|. |. .. . ...|||| .|... .. .|||||||. .|. |||
akvakksarnrtgfseeynsLaalektksvtagrlavnakknRyrnilpyDekrvklkkle..eeagaDYinasyidgekkkkkyiatqgPladtvndfW
QLIWQEKSTIIVMITNIIEEGKVKCQQYWPNSDT-KDYGPFSVTLRE
.|....|.. |||.|...|.|| ||..|||..|. | || . |||.|
elvyenktstivmltelveggktkCeeYWPdadkpknyGsvtvtlve
|
|||||||||
| subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 1097-1307 | 3.2e-43 | 142.9 | In-house | 79-289 (297) | alignment | ||
Range on Protein: 1097-1307
Range on HMM: 79-289/297.0
PDYINAVFINGYKEkkAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQeVCYQYWSNRKLGEY-NISLLNEEIH-NAGYIERKIEVTNdNKAG
||.|| |..|.|. .| . || .| .||.|. | .|..|||| ..|.... | .|||.. .. ..|.. . .. |.|.|..|||. .||
sDyvnasfvkgnkh..rlittqmPmkatvadfWamvldeqvstivmlnddnerdk.kcaryWsdkgvttfGdvsvvllsvsereGfikrelevtk.gkak
DKQQVKQYQITNWDSTGKLT--NPQTILLVIEEMYRTQRKRGNTSIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQ
.. ||||| ..| . . ...| .|.|. . .. .. ...||. ||| ||... . . | | .|.|...| | ..| ||| .||.
arrvvkqyqfveWPdkaverkdsassllklisevrkdfsqnaegPllvhclaGvGrtgvlltidsvvaeakrekevdifglvkklrqerpylvqtkeqyk
GIFQIVLTYLDSFET
....|| .| | .|
fvyvavleallsedt
|
|||||||||
| subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 943-1095 | 3.8e-43 | 142.7 | In-house | 2-152 (318) | alignment | ||
Range on Protein: 943-1095
Range on HMM: 2-152/318.0
IPVDKFGEFVANGHAKGNEGFRNQFGMLDSGESDHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMPGHKdcTNEYINACFIKDYSNQYQYIATQGPVS
|.|... . |.. ...|. . ... .|. |. | . |.| || ||.|||. ||. |. |... |.. . .|||| .| | .. .|||.|.|..
isvedleshvrrlresGelllseeyerlsrseetvtslkslepvnkaknryanilaydhtrvkLqmlegee..gsDyinanyidGyrrkkayiaaqaPlp
NTLVDFWQLIWQEKSTIIVMITNIIEEGKVKCQQYWPNSDTKDYGPFSVTLRE
.|. |||...|. .|..|||.|.. |.||.|...|||..... || |.|.|
etieDfWrmvWeqnsavivmltqeeergkakvhryWPskgsrsygklvvelke
|
|||||||||
| subfamily_PTPRK_pd | Subfamily PTPRK | 1096-1300 | 5.4e-43 | 142.0 | In-house | 70-275 (314) | alignment | ||
Range on Protein: 1096-1300
Range on HMM: 70-275/314.0
HPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSN--RKLGEYNISLLNEEIhNAGYIERKIEVTN-DNK
. ||||| .|..|| .|||.. |. .| ..||... | | ..|||| . .. . |..|| . .. |. .. |.. |. .| .. | |.. .
ssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasivmltelvevgrvkClkyWPedtevygdikvelvetel.laelvvrifrveklarg
AGDKQQVKQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKrGNTSIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQ
....|.|.| ..| . . .. ...| .. .. .| . .. ||.||| ||.|.|.| .. .. ..|||.|||.. |. | .|. |.| .||.
qeeirevrqfqflgWpdhdvPvsatgllklvrrvkksqee.eaGrivvhCsaGaGrtGtfiaidivldmieregvvdvfnavktlrsrkvnmveteeqyk
GIFQIVLT
|....|
fiydvile
|
|||||||||
| subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 958-1098 | 7e-43 | 141.4 | In-house | 12-156 (301) | alignment | ||
Range on Protein: 958-1098
Range on HMM: 12-156/301.0
KGNEGFRNQFGMLDSGEsDHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMPGHKDCTNEYINACFIKDYSNQYQYIATQGPVSNTLVDFWQLIWQEKS
| ...| .|. |..|| |.. ||||. .|| |||| ||.|||||||.|.|.| . |..||||| .|..||.. ..||.|||. .||||||.||||||
khsnkfeeqykelkege.dksctvglseenkalnrfknitvyddnriilkpkpnldlcqreyinasyidgysekkkfiaaqgpmkktlvdfWrliwqekp
TIIVMITNIIEEGKVKCQQYWPNSD--TKDYGPFSVTLRE---HPD
. |||.|| |. | ||.||||||. ....|||.||| . .||
vsivmvtnlkegtkskceqywpnseaeseefgpftvtlvneqvyPd
|
|||||||||
| subfamily_PTPRB_pd | Subfamily PTPRB | 941-1094 | 8.6e-43 | 141.4 | In-house | 5-157 (293) | alignment | ||
Range on Protein: 941-1094
Range on HMM: 5-157/293.0
DMIPVDKFGEFVANGHAKGNEGFRNQFGMLDSGESDHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMPGHKdcTNEYINACFIKDYSNQYQYIATQGP
| ..|| |.|.. .|. . .| ... .| . ..|..|.. .. |. ||. ||. || .|. | .. ... ...|||| .|..|. . ..||||||
kpiklekfeehvkkmkadsdlrfseeyeelkavgkdqavkaaelavnraknrytnilpydhsrvkLaalkdes..gsDYinanyipgynsprefiatqGP
VSNTLVDFWQLIWQEKSTIIVMITNIIEEGKVKCQQYWPNS-DTKDYGPFSVTLR
. .|. |||...|..||.||||.|...|.|||||..|||. .. || .|||
lpetvddfWrmvwekkssiivmltqlvekgkvkCeeYWPadeepvlyGdikvtlv
|
|||||||||
| subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 1095-1299 | 9e-43 | 141.8 | In-house | 87-288 (319) | alignment | ||
Range on Protein: 1095-1299
Range on HMM: 87-288/319.0
EHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCqenknnQEVCYQYWSNR---KLGEYNISLLNEEiHNAGYIERKIEVTNDN
| ||||| |..||. |. .| | |. || .||.|| . |...||.| .. | ||| .. | ....... | | |. |.||...|
efsdyinasfvtGyqrkdkyiaaqGPldntladfWrmiweyncstivllt......kdkcsqywplkivikeerfkvkvdsve.etaeyvvrdielsedg
KAGDKQQVKQYQITNWDSTGKLTNPQTILLVIEE-MYRTQRKRGNTSIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQ
| |.....|. . | |. | .. ... . |........||.||| |||.||. . . ... | | .||..... | |.. || . |
kekdirkitqfhflGwpdvGvpdypsdlmrlvkkvrhltskenhranivvhcsaGvGrtGvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvq
YQGIFQIVL
|. |. .|
ykfiysall
|
|||||||||
| 0050432 | (Phosphotyrosine protein) phosphatases II | 932-1095 | 9.2e-43 | 142.1 | In-house | 15-174 (308) | alignment | ||
Range on Protein: 932-1095
Range on HMM: 15-174/308.0
HGDSSSAKIDMIPVDKFGEFVANghAKGNEGFRNQFGMLDSGESDHTVTVGLTPSNKLLNRFANIVVYDDNRITLrpmpghkDCTNEYINACFIKDY--S
...| ... ..|... ... . |... ... .| | | ... .|.| | || .||. .|. || .|. | | .. |||| ... |
rdtsilvsslklsvldllkllek..aldlglleeefeellsvkplleysvallpenkdkNrykdilpydhsRVkl.......degsdYInAsyvdgyssk
NQYQYIATQGPVSNTLVDFWQLIWQEKSTIIVMITNIIEEGKVKCQQYWPNS---DTKDYGPFSVTLRE
.. ..|||||| .||. |||...|......|||.|...| |..|| ||||.. ... ||.|.|||..
lprkfIatqgPlpntvedFwrmvweqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtlls
|
|||||||||
| subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 1095-1299 | 1.4e-42 | 141.2 | In-house | 51-252 (284) | alignment | ||
Range on Protein: 1095-1299
Range on HMM: 51-252/284.0
EHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCqenknnQEVCYQYWSNRK---LGEYNISLLNEEiHNAGYIERKIEVTNDN
| ||||| ||.||. |. .| . |. || .||.|| . |...||.| .. | ||| .. ....... | . |. |.||...|
efsdyinasfitGyqrkdkyiatqGPldntladfWrmiweyncstivllt......kdkcsqywplkivikeerfkvkvdsve.eseeyvvrdielsedg
KAGDKQQVKQYQITNWDSTGKLTNPQTILLVIEE-MYRTQRKRGNTSIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQ
| |.....|. . | |. | .. ... . |........||.||| |||.||. . . ... | | .||..... | |.. || . |
kekdirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrtgvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvq
YQGIFQIVL
|. |. .|
ykfiysall
|
|||||||||
| subfamily_PTPRG_pd | Subfamily PTPRG | 1097-1307 | 4.4e-42 | 139.0 | In-house | 76-292 (563) | alignment | ||
Range on Protein: 1097-1307
Range on HMM: 76-292/563.0
PDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSN---RKLGEYNISLLNEEIHnAGYIERKIEVTN-DNK
||||| .|.||. .||||.. |. .|. ||.|| ..||. |||. . ...... | .|| . ..|. .. | .||.. | | .|.. . | |
lDYinAnyidGyqkskafiatqgplkdtfddFWrmiWeqnvaiivmitnlvergrrkcdvYWPkdesetygalqvtlieeevl.alytvrtlviknlklk
AG----DKQQVKQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKrGNTSIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTV
.. ....|.||. |.| .| . . | .. ..... ||.||| |||.|.... | ... ..| ...||..|| | |.. |||
kkkqcdteklvrqyhytkWPdhgvPehslpvLifvkkssaanka.eaGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvqte
QQYQGIFQIVLTYLDSFET
||. .....| . | ||
EqYiflhdalleaiasket
|
|||||||||
| subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 1096-1303 | 1.3e-41 | 137.5 | In-house | 71-278 (315) | alignment | ||
Range on Protein: 1096-1303
Range on HMM: 71-278/315.0
HPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSN-----RKLGEYNISLLNEEIhNAGYIERKIeVTNd
. ||||| .|..... ||.| . | . .||.|. . .||.|||. . ..... | ||| . ..|.....||. | ... . ||. ||
dsdyinasyiksvdddkayiasqgPlkasvddfwrmvlqekvttivmvtkkqegdkikcrqywPdrkadsvefGsikvellslea.dtdgvarkl.vtr.
nKAGDKQQVKQYQITNWDSTGKLTNPQTILLVIEEMYRTqRKRGNTSIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQ
|. ....| |.| |.| | . ..| .| |. ... . |...||| |||.||.... ... | . ..|||...| | ..| ||| ..
.kseesrtvtqfqftewPdkGvdkqtssllklikevkad.ngkkefsllvhcsaGvGrtGvvisidevvaqikrtrsvdvfnfvknlrakrpylvqteee
YQGIFQIVLTYLD
| |...|| .|
yafiydavledll
|
|||||||||
| subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 942-1095 | 2.2e-41 | 137.0 | In-house | 3-154 (305) | alignment | ||
Range on Protein: 942-1095
Range on HMM: 3-154/305.0
MIPVDKFGEFVANGHAKGNEGFRNQFGMLDSGesDHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMPGHKdcTNEYINACFIKDYSNQYQYIATQGPV
.| .|.. ... . ... ..|. .|. .| . .... || . || ||...|...||.|| |.. . .. ..||||.... |... .||..|||.
iialddlaayikearvysdkgleaqykslyee..eesidvgkkeankaknrlkeitlldddriiltekesld..dsdyinasyvdgykrkkkyivaqgPl
SNTLVDFWQLIWQEKSTIIVMITNIIEEGKVKCQQYWPNSDTK--DYGPFSVTLRE
||..|||.||..|| . |||.|...|.|| ||.||||.| |. ..|.|||.|..
kntvadfWrliveekvstivmltklveggkdkCrqYWpesktekkefgefsvelks
|
|||||||||
| 0040438 | (Phosphotyrosine protein) phosphatases II | 947-1095 | 3.2e-41 | 137.0 | In-house | 4-149 (317) | alignment | ||
Range on Protein: 947-1095
Range on HMM: 4-149/317.0
KFGEFVANGHAKGNEGFRNQFGMLDSGESDhTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMPGHKDctNEYINACFIKDYSNQYQYIATQGPVSNTLV
.. ... ..... .....| .|.| | | .|.. | || .||. .|. ||..|. | |..|. | . |||| ... .. . ..|||||| .||.
dlllalldllksdftalleefedllslkld.tysvaelpenkdknrypdilpydhsRVkLsplggdld..sdYInAsyvdgpnlkrkfIatqgPlpntve
DFWQLIWQEKSTIIVMITNIIEEGKVKCQQYWPNSDTKDYGPFSVTLRE
|||...|....|.|||.|. | |..||.||||. .|. ||.|.|||..
dFwrmvweqgvtvivmLteleelgrekcaqYwplgetltygdftvtlls
|
|||||||||
| subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 943-1095 | 3.4e-41 | 136.3 | In-house | 5-154 (319) | alignment | ||
Range on Protein: 943-1095
Range on HMM: 5-154/319.0
IPVDKFGEFVANGHAKGNEGFRNQFGMLDSGESDhTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMPGHKDCtnEYINACFIKDYSNQYQYIATQGPVS
|.|... | . . ...|. .....| .|. ...| |.. .. || ||. ||. || |..| ...| .. .|||| || | .. ..||||.|..
ievqeLkerlkalastgetllekefkllkeavnd.tfdsaskeenkkknryqnilaydrtrvvlseldgvegs..dyinasfidgyqerekfiatqaPle
NTLVDFWQLIWQEKSTIIVMITNIIEEGKVKCQQYWPNSDTKDYGPFSVTLRE
||. |||...|.|.| |.||.|.. |..|||...|||. . ..|| . ||| |
ntiedfWrmvWeeessivvmltklveklkvklkkywpeenfeeyGrlivtlee
|
|||||||||
| subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 1096-1303 | 5.8e-41 | 135.1 | In-house | 70-277 (515) | alignment | ||
Range on Protein: 1096-1303
Range on HMM: 70-277/515.0
HPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSN-----RKLGEYNISLLNEEIhNAGYIERKIEVTND
| ||.|| .|.... ||.| . | . .||... . |||.|.|. . ..... | .|| . |.|.....|. | .| | ||..|. .
hsdyfnasyipsfdndkayiasqgPnkasvddfWrlvlqenvttiamvtklkegdkikcgkyWPdkpgdsvkfGsikvelvslea.ctggikrkltvlkg
NKagdKQQVKQYQITNWDSTGKLTNPQTILLVIEEMyRTQRKRGNTSIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQ
.. . | |.. |.| | . ...| .| |. .... . . ...|||| ||| ||.... . . || ..|||.... | ..| ||| .|
dd...srtvtqfhfteWPdkGvpkhtssllklikev.kadhgqythpliihcsaGvGrtGvvisidsvvahakttrmvdvfnfvtnirqkrpylvqtqeq
YQGIFQIVLTYLD
| |...|| .|
yafiygavledll
|
|||||||||
| 0037934 | (Phosphotyrosine protein) phosphatases II | 1096-1301 | 1.4e-40 | 134.7 | In-house | 31-241 (243) | alignment | ||
Range on Protein: 1096-1301
Range on HMM: 31-241/243.0
HPDYINAVFINGYKeKkaFIIAESPMFNTARN----FWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSNRKLGEYNISLLNEEIHNAGYIERKIEVTNDN
||||| .|.... . .|. |. .| . ||.|. . ..|.||||... ...| |.|||.. . . . | .| | ..|. |.....| .
gsdyinanliyvtp.r..liatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywpgevtygdftvtllseehlddytvrtlllenld
KAGDKQQVKQYQITNWDSTGKLTNPQTILLVIEEMYRTQRK-------RGNTSIVIHCSDTVGRSGVFCAAATTINKCkteGvIDVFQVLKSQRIQKPG-
. ...| .|. ..| | ..|. .| ..|.. ... .. ...||| |||.|...|| . . .. | .|.....| | |.||
lddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtliaaylmllll...g.vdleeavkllreqRpgk
SVQTVQQYQGIFQIVLTY
.||| .||. . ...| .
avqtpsqyrflyeallel
|
|||||||||
| subfamily_PTPRB_pd | Subfamily PTPRB | 1096-1304 | 1.5e-40 | 134.0 | In-house | 78-287 (293) | alignment | ||
Range on Protein: 1096-1304
Range on HMM: 78-287/293.0
HPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSNR----KLGEYNISLLNEEiHNAGYIERKIEVTNdn
. ||||| .|.||. .. || . |. .| .||.|. ......|||| | . .. | .|| . |. ...|..|| . .. |......
gsDYinanyipgynsprefiatqGPlpetvddfWrmvwekkssiivmltqlvekgkvkCeeYWPadeepvlyGdikvtlvaee.eledwvirelkiek..
kAGDKQQVKQYQITNWDSTGKLTNPQTILLVIEEMYRTQ-RKRGNTSIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQ
. ....|.||. | | | ...|.| .... ... .. .. ||.||| |||.|.| | . ... ..| ..|.| .. . | .. |||..|
.ekeerkvrqyhftsWpdhgvPektktlldfvrtvreaiektaskrPivvhCsaGvGRtGtfialdrllqaieeedyvdifgivaelReeRnllvqtekq
YQGIFQIVLTYLDS
| | | ||..| .
Yifihqcvldllrk
|
|||||||||
| 0036941 | (Phosphotyrosine protein) phosphatases II | 957-1095 | 4.2e-40 | 133.3 | In-house | 9-143 (297) | alignment | ||
Range on Protein: 957-1095
Range on HMM: 9-143/297.0
AKGNEGFRNQFGMLDSGESDHTVTVGLTPSNKLLNRFANIVVYDDNRITLrpmpghKDCTNEYINACFIKDYSNQYQYIATQGPVSNTLVDFWQLIWQEK
.... ... .| |.. . . .|.| | |. .||. .|. ||..|. | .| . ||||.... |. ....|||||| .||. |||...|...
llflalllkefeellpllllgslsvallpenleknRykdilpydhtRVkl......ddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqn
STIIVMITNIIEEGKVKCQQYWPNS--DTKDYGPFSVTLRE
.|.|||.|. .| |..||.||||. ... ||.|.|||..
vtvIvmltelvelgrekcaqywpleegesltygdftvtlls
|
|||||||||
| subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 1097-1306 | 7.3e-40 | 131.8 | In-house | 75-285 (288) | alignment | ||
Range on Protein: 1097-1306
Range on HMM: 75-285/288.0
PDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSNR----KLGEYNISLLNEEiHNAGYIERKIEVTndnK
||||| .|.|.|.||..| . .|. .| .||... ..... |||| . .... | .|| . . |. .. |.... . ...||... |
aDYinasyidgekkkkkyiatqgPladtvndfWelvyenktstivmltelveggktkCeeYWPdadkpknyGsvtvtlvesk.eledfvlrkllle...k
AGDKQQVKQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKRgNTSIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQ
... ...||| . | .| . . .| ... . .. . |..|||. |||.|.| |. . |.. ..| .|||. ... | |.. |||..||.
kkteleitqyqylaWpdhgvPeskapllellrqvkvanqad.tgpiivhCsaGvGrtgtFialdalidaveeedyiDvagtvaklRkqRallvqtlkqYe
GIFQIVLTYL--DSFE
|....|. |. .
fiyevllslieedgva
|
|||||||||
| 0047943 | (Phosphotyrosine protein) phosphatases II | 956-1095 | 1e-39 | 132.1 | In-house | 7-143 (273) | alignment | ||
Range on Protein: 956-1095
Range on HMM: 7-143/273.0
HAKGNEGFRNQFGMLDSGESDHTVTVGLTPSNKLLNRFANIVVYDDNRITLrpmpghKDCTNEYINACFIKDYSNQYQYIATQGPVSNTLVDFWQLIWQE
...|. ... .| .| | ..| .|.| | || .||. .|. ||..|. | .| .. |||| ... | . ..|||||| .||. |||...|..
kllgltllleefelllslkplltysvallpenkdknrykdilpydhsrvkl......gdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvweq
KSTIIVMITNIIEEGKVKCQQYWPNSD---TKDYGPFSVTLRE
....|||.|...| |..|| ||||.. .. ||.|.|||..
nvrviVmLtelvelgrekcaqYwpleggelsltygkftvtlls
|
|||||||||
| subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 1096-1304 | 1.7e-39 | 130.8 | In-house | 75-290 (325) | alignment | ||
Range on Protein: 1096-1304
Range on HMM: 75-290/325.0
HPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNvTAIVMLCQENKNNQEVCYQYWSNR-----KLGEYNISLLNEEIHnAGYIERKIEVTNd
. ||||| ... .|.|. |. | .|. .| ..|... | . ...|.. | ..... | .|| .. ..| ...| | . |. |...| .
ssdyinasylrddkkkdvflaaqaPltatindlWrlvldWr.csvvvvlneldlgkdrcavywpkemgksktfGglevklrtieei.sdyvhrvldvkq.
NKAGDKQQVKQYQITNWDSTGKLTNPQTILLVI---EEMYRTQR--KRGNTSIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSV
| |. . |||.|. || | | |.. .. ... . . .. | |..|||. |||.||| . . ..| .| .|.|...| | ..| |
vkkGetrsvkqfqlqswddmGvqkrpatlisilqlvkavservtantkastpilvhcsaGvGrtGvfislysalakvieesrvdifgfvkklrkdrpsmv
QTVQQYQGIFQIVLTYLDS
.|| || |.. . .. |
etvdqyiliyealveayms
|
|||||||||
| 0046845 | (Phosphotyrosine protein) phosphatases II | 963-1095 | 2.1e-39 | 131.0 | In-house | 2-141 (284) | alignment | ||
Range on Protein: 963-1095
Range on HMM: 2-141/284.0
FRNQFGMLDSGESDH--TVTVGLTPSNKLLNRFANIVVYDDNRITLRPMPGHkDCTNEYINACFIKDY-----SNQYQYIATQGPVSNTLVDFWQLIWQE
.. .| .| | .. ...|.| | |. .||. .|..||..|. |....|. . ...|||| ... | .. ..||||||..||. |||...|..
leeefeellsltvklllslsvallpenlsknRykdilpydhsRVklksldgd.ledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweq
KSTIIVMITNIIEEGKVKCQQYWPNSD-TKDYGPFSVTLRE
....|||.|...| |..|| ||||... .. ||.|.|||..
nvrvIVmltelvengrekcaqYwplegevltygdftvtlls
|
|||||||||
| subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 1095-1300 | 3.6e-39 | 129.5 | In-house | 75-277 (315) | alignment | ||
Range on Protein: 1095-1300
Range on HMM: 75-277/315.0
EHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSNRKL--GEYNISLLNEEiHNAGYIERKIEVTNDNK
.| ||.|| ||.||. |. .| |..| .. ..||... . ... |||| . ..... . .|| ..|. |.. ... .|| .| | | . |. ...
phsdyvnanfidGynkkrryiaaqgpnvasvkdfwrlvfeedigkivmltnlvegekrkaekywpdkkviyGkitvtrksee.vnteytvrtlsvvfgdn
AgdkQQVKQYQITNWDsTGKLTNPQTILLVIEEMYRTQRKRGNTSIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQ
..| |...| | . .... . |. . . .. ..||.|||. |||.| |.. . ... ..| .|||..... | .. . ||...|||
i...revvqlhytswp.dmgvpkytiplmnlirtvkqhhtnsvgaivvhcsaGvGrtGtfitldavldqaeaenaidvynfitgvrqnrikmvqvaeqyq
GIFQIVLT
|....|
fiydalle
|
|||||||||
| subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 950-1095 | 4.7e-39 | 129.4 | In-house | 16-162 (298) | alignment | ||
Range on Protein: 950-1095
Range on HMM: 16-162/298.0
EFVANGHAKGNEGFRNQFGMLDSGES---DHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMPGHKDCtnEYINACFIKDYSNQYQYIATQGPVSNTLV
...| ..|. |. ..| |.|..| ... .|. .|.|| ||.|.|. .| |. |. . . ... .|||| |.. |... .||||.|. .|..
klaavkkkkkltgyalefqrlnsvsseieeeekevarkpenkkkNRyadiialdssRvvLekedadees..dYiNAsflhaykgrnafiatqaPltetve
DFWQLIWQEKSTIIVMITNIIEEGKVKCQQYWPNSDTKDYGPFSVTLRE
|||.....|... |||.||. | .|.|...|||.. .. || ..|.|..
dFWrmvteedigtiVmltnleeldktkyhkywPdegketygeitvslls
|
|||||||||
| subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 1095-1303 | 7.6e-39 | 128.4 | In-house | 55-269 (274) | alignment | ||
Range on Protein: 1095-1303
Range on HMM: 55-269/274.0
EHPDYINAVFINGYKE-KKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSNRKL----GEY-NISLLNEE-IHNAGYIERKIEV
| .|||| .| ||.| .||.. . |. || .||.|| ..|. |||| . . .|.. | .|. ... ..| .... .|. ... .| ||. .
edssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneqkCavyfPdaedyeiserygdveikvekiverndysvrklvl
TNDNKagdKQQVKQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKRGNT--SIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSV
. .. ...|| | |.| . ...|.| ...|. ...... . ..|.||| .|| |.| |. .... . |.|.||... |... | |
kyler...ersvkhywytdWPdhksPddantlldlvleveesreeenaklapvvvhCsaGiGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGmv
QTVQQYQGIFQIVLTYLD
|| .||. |.... ||
qtseqyelihralclylk
|
|||||||||
| subfamily_Ptp69D_pd | Subfamily Ptp69D | 943-1092 | 8e-39 | 128.6 | In-house | 4-151 (307) | alignment | ||
Range on Protein: 943-1092
Range on HMM: 4-151/307.0
IPVDKFGEFVANGHAKGNEGFRNQFGMLDSGESDHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMPGHKDCtnEYINACFIKDYSNQYQYIATQGPVS
|..|. | . . . . ..|. . . .| . |.|.. .|. |.| ||. .|. .|..|. |....|..| .|||| ||| | .. ..|| |.||
iaiddleealksrkrdtdfglakeyekLeareidkstkvsekkenalknRyedikafDktRvkLkkingkeds..dYinasfikgykekkkfiaaqdPve
NTLVDFWQLIWQEKSTIIVMITNIIEEGKVKCQQYWPNSDTKDYGPFSVT
.|. |||..|.. ..|.|||..|. | . ||..|||. |.. || |.
atigDfWRmiaeqevtlivmlsnlteknrkkcakYWpiedevqygdilvk
|
|||||||||
| subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 956-1093 | 8.2e-39 | 128.4 | In-house | 10-146 (281) | alignment | ||
Range on Protein: 956-1093
Range on HMM: 10-146/281.0
HAKGNEGFRNQFGMLDSGESDHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMpgHKDCTNEYINACFIKDYSNQYQYIATQGPVSNTLVDFWQLIWQE
... |.|| ... | . . |.| | .. |.| ||. ||| || |... | ... ...|||| |.. |... .|||||||| ..||.|||..|..
sqndnaGfieeyeklaaigvdntataskadenvlknrYsnivaYDatrvkvtpn..eenkntDYinanfvpgykgekeyiatqgPvPaslvafWqmvweq
KSTIIVMITNIIEEGKVKCQQYWPNSD-TKDYGPFSVTL
| ..|||.|. ||.||.|| .|||. . . || . |.
kvsaivmvtreieagklkChrYWPddnselkygdvtvks
|
|||||||||
| subfamily_CG7180_pd | Subfamily CG7180 | 1096-1302 | 1.5e-38 | 127.1 | In-house | 69-290 (296) | alignment | ||
Range on Protein: 1096-1302
Range on HMM: 69-290/296.0
HPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQeVCYQYWSNR---KLGEYNISLLNEEIHNAGY-----IERKIEV
. ||||||..... ||..|. | |. .| .||... |... |.|.|... .. . .|| |. . || . ...|. . . .||
ksdYinavyvdsflkkkeyivteapkketvdefWrlvydeeisavvvLtktfdfak.mypsywpnkskeqygeifveiveekqyanlkirtfkltkkiva
T---NDNKAGDKQQVKQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKRG-----NTSIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRI
. . . .. ||..|.| |.. |. . |. . .. |. |.. . .|...|| ..||||..|. .... . |. .|||. .| |.
lteqekqvkaetRivklfqlteWeledkvPlstnalielrrrvrlwrekvdedpeegPvvvvssdGasRsGvylaidanlelvekeeevdvFeavktlrr
QKPGSVQTVQQYQGIFQIVLTYL
..|. |..|..|. |....| ..
sRpqLvenveeYkyiYdvlleav
|
|||||||||
| 0043336 | (Phosphotyrosine protein) phosphatases II | 943-1095 | 1.6e-38 | 128.2 | In-house | 2-150 (278) | alignment | ||
Range on Protein: 943-1095
Range on HMM: 2-150/278.0
IPVDKFGEFVANGHAKGNEGFRNQFGMLDSGESdHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMPGHKDctNEYINACFIKDYSNQYQYIATQGPVS
|.| .. ..... ..... .....| |.| | ...| | || .||. .|. || .|. | ...|. | . |||| ... |. . ..|||||| .
isvkdllkallelllnlktllllefeellsfkl.dtysiallpenkdknrykdilpydhsrvklsllggdld..sdYinAsyvdgynvprkfiatqgPlp
NTLVDFWQLIWQEKSTIIVMITNIIEEGKVKCQQYWPnSDTKDYGPFSVTLRE
.|. |||...|....|.|||.|. | |.|||.|||| .... ||.|.|||..
etvedFwrmvwelgvttivmLtelvelgrvkcaqYwp.ggsltygdftvtllk
|
|||||||||
| subfamily_PTPRA_pd | Subfamily PTPRA | 936-1095 | 2.1e-38 | 127.1 | In-house | 7-164 (330) | alignment | ||
Range on Protein: 936-1095
Range on HMM: 7-164/330.0
SSAKIDMIPVDKFGEFVANGHAKGNEGFRNQFGMLDSGESDHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMPGHKDctNEYINACFIKDYSNQYQYI
.. | .||.|. | . | |. ||..| | .|. . |. . || ||. ||. || .|. | .. |... .|||| ||. | .. ..|
gnkkyfplpvekleeeirirsaddnklfreefnalPagpiqatlelaskeenkeknrvvnilPydfsrvilsvkeGvee..sdyinasfidGykekdkfi
ATQGPVSNTLVDFWQLIWQEKSTIIVMITNIIEEGKVKCQQYWPNSDTKDYGPFSVTLRE
|.||| ..|. |||..||. ||. |||.|.. | . ||.||||. . || |....
aaqGPkeetvedfwrmiweqksativmltelkerkeekcaqywPdeGlvtyGnirveved
|
|||||||||
| subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 956-1095 | 2.1e-38 | 126.8 | In-house | 4-138 (283) | alignment | ||
Range on Protein: 956-1095
Range on HMM: 4-138/283.0
HAKGNEGFRNQFGMLDSGESDHTVTVglTPSNKLLNRFANIVVYDDNRITLRPMPGhkdctnEYINACFIK---DYSNQYQYIATQGPVSNTLVDFWQLI
....|. ||... | . | .... . || ||. .||..| .|. |.. . .||||.|| .| .. .||..|.|. .| ||||...
rvnnnklfrevlkrlsvpdldadias..adenkrknrnqeivpadqwrvelksesr......dyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmv
WQEKSTIIVMITNIIEEGKVKCQQYWPNSDTKDYGPFSVTLRE
..|| | |||.|.. |. ..|| ||||. ..|||.| ||||.
fdekitaivmltklqedlrikCsqyWPkrGsedyGeftvtlrk
|
|||||||||
| DSPc_SM00195 | 963-1095 | 6.3e-38 | 126.0 | In-house | 2-134 (263) | alignment | |||
Range on Protein: 963-1095
Range on HMM: 2-134/263.0
FRNQFGMLDSGESDHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMPGHkdCTNEYINACFIKDYSNQYQYIATQGPVSNTLVDFWQLIWQEKSTIIVM
....| |.. .|....| . ..|| ||. ||..||..|. | . ... ...|||| .|| .... .||||||| ..|. |||...|.||..||||
lkeefekleestspketteaekkknksknRyknilpydhtrVklkkeekk..egsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivm
ITNIIEEGKVKCQQYWPNS--DTKDYGPFSVTLRE
.|. |.|| ||..|||.. .....| .||.|.|
lteeeengkekcdrywpeesggketfgkisvklve
|
|||||||||
| PTPc_SM00194 | 963-1095 | 6.3e-38 | 126.0 | In-house | 2-134 (263) | alignment | |||
Range on Protein: 963-1095
Range on HMM: 2-134/263.0
FRNQFGMLDSGESDHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMPGHkdCTNEYINACFIKDYSNQYQYIATQGPVSNTLVDFWQLIWQEKSTIIVM
....| |.. .|....| . ..|| ||. ||..||..|. | . ... ...|||| .|| .... .||||||| ..|. |||...|.||..||||
lkeefekleestspketteaekkknksknRyknilpydhtrVklkkeekk..egsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivm
ITNIIEEGKVKCQQYWPNS--DTKDYGPFSVTLRE
.|. |.|| ||..|||.. .....| .||.|.|
lteeeengkekcdrywpeesggketfgkisvklve
|
|||||||||
| 0045450 | (Phosphotyrosine protein) phosphatases II | 942-1094 | 1.1e-37 | 125.8 | In-house | 8-170 (307) | alignment | ||
Range on Protein: 942-1094
Range on HMM: 8-170/307.0
MIPVDKFGEFVANGHAKGNEGFRNQFGMLDSGES--DHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMPGHkDCTNEYINACFI--------KDYSNQ
.|.. |. .|. ......|.. .| .| | . .. ...| | || .||. .|. ||..|. | ...|. . .. |||| .. . | ..
fidalkllllvllllldfltgllkefekllsvtvfllgeysiallpenkdknrykdilpydhtRVklssldgs.ledsdYiNAsyvrvpllllldgydlk
YQYIATQGPVSNTLVDFWQLIWQEKSTIIVMITNIIEEGKVKCQQYWPNSD-TKDYGPFSVTLR
..|||||| ..|. |||...|....|.|||.|. .| |..|| ||||... .. ||.| |||.
rkfIatqgPlpetvedFwrmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtll
|
|||||||||
| 0039614 | (Phosphotyrosine protein) phosphatases II | 944-1095 | 4.3e-37 | 123.6 | In-house | 15-162 (297) | alignment | ||
Range on Protein: 944-1095
Range on HMM: 15-162/297.0
PVDKFGEFVANGHAKGNEGFRNQFGMLDSGESDhtVTVGLTPSNKLLNRFANIVVYDDNRITLRPMPGHkDCTNEYINACFIKDYSN-QYQYIATQGPVS
|.. . .. .|... .....| .| | | ...| | || .||. .|. ||..|. | |..|. | . |||| ... |. . ..|||||| .
plsvldlllllekansktllllefeellslkpd..ysiallpenkdknrykdilpydhsrvklkpedgv.dldsdYinAsyvdgydlltrkfIatqgPlp
NTLVDFWQLIWQEKSTIIVMITNIIEEGKvKCQQYWPNSDTkDYGPFSVTLRE
.|. |||...|....|.|||.|. .| |. ||.||||.. . ||.|.|||..
etvedFwrmvweqgvtvivmLtklvelgr.kcaqywpeegg.tygdftvtllk
|
|||||||||
| subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 29-148 | 4.7e-37 | 122.3 | In-house | 166-283 (301) | alignment | ||
Range on Protein: 29-148
Range on HMM: 166-283/301.0
LNEETFNGYIERKFEVKNNNtgATQSVTQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQ
... . ||||||||.||... ....|.|.|.|.| | . .|.|.| ||... .|.| | .||||||||.|| ..|. .. || |||.||||
iqdgsnngyierkfkvksdk..sswdvlqlqvtdWpqdGvvreprtvLqviddvihrqqkigggpvvVHCSdtVsrsGvYcsvsiglEQckaegVVdvfq
VLKSQRIQKPGSVQTVDRII
| |. | .||| |.| . .
vtkavrrskpgaVtTLeqyt
|
|||||||||
| subfamily_PTPN6_pd | Subfamily PTPN6 | 950-1093 | 1.6e-36 | 120.9 | In-house | 15-160 (306) | alignment | ||
Range on Protein: 950-1093
Range on HMM: 15-160/306.0
EFVANGHAKGNEGFRNQFGMLDSGESDHTV--TVGLTPSNKLLNRFANIVVYDDNRITLRpmpGHKDCTNEYINACFIKD--YSNQYQYIATQGPVSNTL
|. ... ....|| ..| |. |. ... . | |.|| ||. ||. .|..|..|. .. ..|||| .||. ... .|||||| ...|.
elekeeeslekagfeeefeelqqeeakkllsrkegakpenkeknryknilPfDhtrvilk...epsvpgsdyinanyikkevkgsdksyiatqgclettv
VDFWQLIWQEKSTIIVMITNIIEEGKVKCQQYWPNSD-TKDYGPFSVTL
|||...|||.|..|||.|. .| || || .|||.. ...|| |||
sdFWrmvwqensrvivmttkevErgkekCarYWPdeeekeeyGkisvtn
|
|||||||||
| subfamily_PTPN6_pd | Subfamily PTPN6 | 1097-1304 | 1.7e-36 | 120.8 | In-house | 81-299 (306) | alignment | ||
Range on Protein: 1097-1304
Range on HMM: 81-299/306.0
PDYINAVFINGY--KEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSN----RKLGEYNISLLNEeIHNAGYIERKIEVTND
||||| .|.. ...|..| .. . .| .||.|. . | . |||. .|. ..| |..|| . .. |..... ..| ..| || |.. |..
sdyinanyikkevkgsdksyiatqgclettvsdFWrmvwqensrvivmttkevErgkekCarYWPdeeekeeyGkisvtnvse.ksladYilRelsvskk
NKAGDKQQVKQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKRG---NTSIVIHCSDTVGRSGVFCAAATTINKCKTEGV---IDVFQVLKSQRIQKPGS
.|......| ||. ..| | ..|...| .|.. | |.. . .||.|||. .|| | | . ... ...|. ||. .. || | |. |
kkkkeerevfqyhfksWPdhgvpkdpgavLdfledvnrkqeeleeaeagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsgl
VQTVQQYQGIFQIVLTYLDS
||| |||. ..... .|...
vqteqqykfvykaikkyiet
|
|||||||||
| subfamily_PTPN9_pd | Subfamily PTPN9 | 1095-1302 | 6.2e-36 | 118.9 | In-house | 68-290 (297) | alignment | ||
Range on Protein: 1095-1302
Range on HMM: 68-290/297.0
EHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWS-----NRKLGEYNISLLNEEIHNAgYIERKIEVTN
|. ||||| |..|||.||||| . |. .| ..||.|. ...| ||| . . . | ||| . |....| .. | ... | .|..|..|
easdyinanfvdGykqkkafiatqGplkktvsdfWrmvWeqevlvivmttrvvergrlkcgqyWpleeessaefgdlsvsnveveeeed.ykvrvleikn
dNKAGDKQQVKQYQITNWDSTGKLTNPQTILLVIEEMYRTQR---------KRG---NTSIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQ
| .....| .|.. | | . ...| |.|.. ..| ..| . ||.||| .||.| |.. .... ...|..||....|
.vkteesrkvthfqflsWPdyGvPssaaslldvlekvrekqalavkelgdewkghpsgPPivvhcsaGiGrtGtfitldiclsrleevgtvdvvetvkll
RIQKPGSVQTVQQYQGIFQIVLTYL
| |. |.|| .||. .. || |
rtqrafsiqtpeqyefcylavleya
|
|||||||||
| subfamily_PTPN23_pd | Subfamily PTPN23 | 1097-1302 | 1.6e-35 | 117.4 | In-house | 67-280 (288) | alignment | ||
Range on Protein: 1097-1302
Range on HMM: 67-280/288.0
PDYINAVFINGYKEK-KAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSNR-----KLGEYNISLLNEEiHNAGYIERKIEVTND
||||| |... ||.. .|. .|. ||.|. .. . |||| .... ... . .|| .. | |.....| ... . ..||.....
DDYinAsfvkdlspgcPdfiatqaPlqstlnDFWlmvyeqkssviVmllskeelgkpkvdrYwPedkgetvkfgdlsvtlksvr.etethvervlkletl
nKAGDKQQVKQYQITNWDSTGKLTNPQTILLVI---EEMYRTQRKRGNTSIVIHCSDTVGRSGVFCAAATTINKCK-TEGVIDVFQVLKSQRIQKPGSVQ
.| ...|. |.|.| . | |.|.| .. |..|...... .| .|.||| |||.|||. . ... . .|..|. ||.. | |. .||
.dadavksvshlqltsWpelGvPasPetllqfldevesayeavqrksktPlvvhCsaGvgRtgvfalvyaavrelekgnglldiiqvvsrlreqRrfmvq
TVQQYQGIFQIVLTYL
...|.. ...||..
ekeqlkfsyeavleaa
|
|||||||||
| subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 1097-1303 | 2.5e-35 | 116.8 | In-house | 48-265 (270) | alignment | ||
Range on Protein: 1097-1303
Range on HMM: 48-265/270.0
PDYINAVFINGYKE-KKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSNRKLG-----EYNISLLNEE-IHNAGYIERKIEVTn
|||| ...|... ||..| | .|. .| ..||.|| ...||||||. . . .... | .||.... . .|. |... .. ||| ......
taYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkekvkledgkikvlalseekeegyiltrlrle.
dnKAGDKQQVKQYQITNWDSTGKLT------NPQTILLVIEEMYRTQRKRGN-TSIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRIQKP
. |..... .. ..| | . ... .| ..... |.... . . ...|||. |||.|.. | .... .... .|| .... | ...
..ekgeerrlvHfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcsaGvgRtGtlialDiavrlLeetkkvdvlaiieelRkdRm
GSVQTVQQYQGIFQIVLTYLD
||...||. ... |..| .
alvqhpeqyeflykavveyae
|
|||||||||
| Y_phosphatase | Protein-tyrosine phosphatase | 987-1094 | 4.6e-35 | 116.5 | Pfam-A | 1-106 (235) | alignment | ||
Range on Protein: 987-1094
Range on HMM: 1-106/235.0
NKLLNRFANIVVYDDNRITLRPMPGHKDctneYINACFIKDYSNQYQYIATQGPVSNTLVDFWQLIWQEKSTIIVMITNIIEEGKVKCQQYWP--NSDTK
|| ||. .|..||..|. |. .|..| |||| ..| |... ..||||||...|. |||...||||...|||.|. |.|..||.|||| .....
nkkknRykdilpydktrvklkgsegpsd....YInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesl
DYGPFSVTLR
|| ..|.|.
tygdikvelk
|
|||||||||
| Y_phosphatase | Protein-tyrosine phosphatase | 987-1094 | 4.6e-35 | 116.5 | In-house | 1-106 (235) | alignment | ||
Range on Protein: 987-1094
Range on HMM: 1-106/235.0
NKLLNRFANIVVYDDNRITLRPMPGHKDctneYINACFIKDYSNQYQYIATQGPVSNTLVDFWQLIWQEKSTIIVMITNIIEEGKVKCQQYWP--NSDTK
|| ||. .|..||..|. |. .|..| |||| ..| |... ..||||||...|. |||...||||...|||.|. |.|..||.|||| .....
nkkknRykdilpydktrvklkgsegpsd....YInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesl
DYGPFSVTLR
|| ..|.|.
tygdikvelk
|
|||||||||
| 0045098 | (Phosphotyrosine protein) phosphatases II | 971-1095 | 5.4e-35 | 116.5 | In-house | 17-127 (278) | alignment | ||
Range on Protein: 971-1095
Range on HMM: 17-127/278.0
DSGESDHTVTVGLTPSNKLLNRFANIVVYDDNRITlrpmpghkdctnEYINACFIKDYsnQYQYIATQGPVSNTLVDFWQLIWQEKSTIIVMITNIIEEG
. . ..|..| ..|. .||. .|. || .|. .|||| .|. | . ..|||||| .|. |||...|....|.|||.|. .| |
lllgipseitpalylgnldknRykdilpydhsrVk............dYINAsyidgy..pkkfIatqgPlpstvadfwrmlwelgitvivmltelvelg
KVKCQQYWPNSDTKDYGPFSVTLRE
..|| ||||..... ||.|.||| .
rekcaqywpeggsltygdftvtlls
|
|||||||||
| subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 21-146 | 1.1e-34 | 115.0 | In-house | 145-271 (305) | alignment | ||
Range on Protein: 21-146
Range on HMM: 145-271/305.0
LGEYNIILLNEETFNGYIERKFEVKN-NNTGATQSVTQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCK
.||....| .|.|...|||||... . .. ...|.|||.|.| | . . ..| .|... ..|.| .....||||..|||. .|.| ....|
fgefsvelksektasdyieRklkisiededkesrtvlqyqltdWPdhGvpqfatsllslikrvqkdqkkdkgvpllVhCsagvgRtGvfiavdialerlk
TEGVIDVFQVLKSQRIQKPGSVQTVDR
.|.|.|||.||| | .... ||| |.
kEevvdvfevlkqlRskrmkmvqtldq
|
|||||||||
| subfamily_PTPN9_pd | Subfamily PTPN9 | 950-1092 | 9.4e-34 | 111.8 | In-house | 5-147 (297) | alignment | ||
Range on Protein: 950-1092
Range on HMM: 5-147/297.0
EFVANGHAKGNEGFRNQFGMLDSGESDHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMPGHKdcTNEYINACFIKDYSNQYQYIATQGPVSNTLVDFW
|.|| ..||..| .... . . . |... ...| ||..... ||. |..| ..... . .|||| |. | .. .||||||. .| |||
elvayvkekgkrGlskeyaeirnepveGtflasklranleknrytdvlcydetrvvlakvdede..asdyinanfvdGykqkkafiatqGplkktvsdfW
QLIWQEKSTIIVMITNIIEEGKVKCQQYWP--NSDTKDYGPFSVT
...|... .|||.| ..|.|..||.|||| . .....| .||.
rmvWeqevlvivmttrvvergrlkcgqyWpleeessaefgdlsvs
|
|||||||||
| subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 1097-1303 | 9.8e-34 | 111.4 | In-house | 65-278 (287) | alignment | ||
Range on Protein: 1097-1303
Range on HMM: 65-278/287.0
PDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSNR----KLGEYNISLLNEEIHNAGYIERKIEVTNdNK
||||| .. .|....||| | .|. | |.||... .......... .| .. . ||.|| .| ..| | . ||. .| . | | . . . .
sdyinanyvasytddeafiaaqgPiaatvrdfwravletrsasvitmtreveearlkcykywPerevPmrvGGysvvlldydikePeygvralrlid.le
AGDKQQVKQYQITNWdsTGKLTNPQ---TILLVIE--EMYRTQRK-RGNTSIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQ
. . . |||... .| | | | .|.. . .|. . .|.|.. .||||.. | . ... . | .|| .|. | .. . ||
trearvvkqldllsw..PdkvlaPtavglirfvldvkqhielardasevGPlvvhddvGiGrsGillatlvlvsrledlGrvdvaavvirlreyraalvq
TVQQYQGIFQIVLTYLD
.| |.. ... . ||
avvqlrllyealvtyyk
|
|||||||||
| subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 942-1095 | 2.3e-33 | 110.5 | In-house | 5-154 (315) | alignment | ||
Range on Protein: 942-1095
Range on HMM: 5-154/315.0
MIPVDKFGEFVANGHAKGNEGFRNQFGMLDSGEsDHTVTVGLTPSNKLLNRFANIVVYDDNRITLrPMPgHKDCTNEYINACFIKDYSNQYQYIATQGPV
||.|.. .||. .| ..||.... . |. | . | || ||. ||. || |. | |. .| .|.|| ||. |. . .|||.|||
pipldqlityvaqkkastkngfkqdyesipggq.lhpldvakkienkqknryiniiaydksrvql.pll.endphsdyvnanfidGynkkrryiaaqgpn
SNTLVDFWQLIWQEKSTIIVMITNIIEEGKVKCQQYWPNSdTKDYGPFSVTLRE
... |||.|...|. . |||.||..|. | |...|||. ||...||...
vasvkdfwrlvfeedigkivmltnlvegekrkaekywpdk.kviyGkitvtrks
|
|||||||||
| subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 981-1094 | 2.4e-33 | 110.4 | In-house | 3-113 (250) | alignment | ||
Range on Protein: 981-1094
Range on HMM: 3-113/250.0
VGLTPSNKLLNRFANIVVYDDNRITLRPMPGHKDCtnEYINACFIKDYSNQYQYIATQGPVSNTLVDFWQLIWQEKSTIIVMITNIIEEGKVkCQQYWPN
|. |.|| ||.|.|. .| |. | . | |.. .|||| |.. |... .||||||...|..|||.....|||. |||.||. |..|. ..||||
vakkpqnkeknryadiialdssrvvLekekgdkes..dyinasflhgyderkafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqywPv
SDTKDYGPFSVTLR
.. || |.|
ekaekyGdvtvsll
|
|||||||||
| subfamily_PTPN3_pd | Subfamily PTPN3 | 1091-1299 | 2.6e-33 | 110.1 | In-house | 58-272 (280) | alignment | ||
Range on Protein: 1091-1299
Range on HMM: 58-272/280.0
VTLREHP-DYINAVFIN----GYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSN----RKLGEYNISLLNEeIHNAGYI
|.|.| . ||||| ..| . . . .|.. |. .|| .||.|. ..... |||| . . . |.||| . ..||... . .| .. |.
vklkesetdyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqksslivmlttlverGrvkChqyWPetedeleygefsvkceke.detksyv
ERKIEVTNDNKaGDKQQVKQYQITNWDSTGKLTNPQTILLVIEEMyRTQRKRGNTSIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRIQK
|.. ... .. ..... | | ..| | .... .| ..|.. |..|. .. .|.||| .||.||. . |.. . .. . . .... | |.
lrelvlkdket.keerkilqlqylaWpdhgvPddsadflefverv.rklrsgkeePvvvhCsaGigrtGvlilletalalieaaepvypldivrtmrdqr
PGSVQTVQQYQGIFQIVL
|||..||. . . .|
amlvqtasqykfvCeail
|
|||||||||
| subfamily_PTPRK_pd | Subfamily PTPRK | 962-1093 | 3.2e-33 | 109.9 | In-house | 23-146 (314) | alignment | ||
Range on Protein: 962-1093
Range on HMM: 23-146/314.0
GFRNQFGMLDSGesdhtVTVGLTPSNKLLNRFANIVVYDDNRITLRPMPGhkDCTNEYINACFIKDYSNQYQYIATQGPVSNTLVDFWQLIWQEKSTIIV
||.... | | . |. ||. .|. || |..| .. | | ..|||| .| | . ..|.||||. .|. |||.|...|... ||
gfkeeyeslfeg.....wdaakkdenreknrsgdilaydrsrvflitidg..dpssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasiv
MITNIIEEGKVKCQQYWPNsDTKDYGPFSVTL
|.|...|.|.||| .|||. ||. ||.. |.|
mltelvevgrvkClkyWPe.dtevygdikvel
|
|||||||||
| 0040439 | (Phosphotyrosine protein) phosphatases II | 978-1095 | 4.4e-33 | 110.3 | In-house | 2-117 (249) | alignment | ||
Range on Protein: 978-1095
Range on HMM: 2-117/249.0
TVTVGLTPSNKLLNRFANIVVYDDNRITLRPMPGhkDCTNEYINACFIKDYSNQYQYIATQGPVSNTLVDFWQLIWQEKSTIIVMITNIIEEGKVKCQQY
...|.| | || .||. .|. || .|. | ..|| . |||| .|. | . ..|||||| ..|. |||...|....|.|||.|. | |..||.||
eysvallpenkdknrypdilpydhsrvklsilpg..lflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqy
WPNSDTKDYGPFSVTLRE
||..... || |.|||..
wplggsleygdftvtlls
|
|||||||||
| 0036282 | (Phosphotyrosine protein) phosphatases II | 1098-1296 | 1.2e-32 | 108.4 | In-house | 3-164 (174) | alignment | ||
Range on Protein: 1098-1296
Range on HMM: 3-164/174.0
DYINAVFINGYKEKKAFIIAESPMFntarnFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSNrklgeynisllneeihnagyierkievtndNKAGDKQ
||||| ..... . .|. |. ||.|. . ..|..|||..|. .. . |..||. .. ..
dyinaspldlsyitprliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe..............................lredler
QVKQYQITNWDSTGKLTNPQtILLVIEEMYRTQRKRGNTSIVIHCSDTVGRSGVFCAAATTINKCKtEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQ
. ||. ..|. | . .. .| ....... . . .. ...||| |||.|...|| . . |...|........| |.||.||| .||. . .
lgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtpsQyrflyy
|
|||||||||
| subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 1091-1300 | 2.8e-32 | 106.8 | In-house | 50-257 (267) | alignment | ||
Range on Protein: 1091-1300
Range on HMM: 50-257/267.0
VTLRE-HPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQY--WSNRKLGEYNISLLNEEIHNaGYIERKIEV
| ||. .|||| ...||| |.|||. . |. || .|...| |..|. ||.| . ..| . .| . . |. | | .|.
vilrtkeeeyinasyvegyktknafivtqdplkntitdfltvihdqkvpvivlltkvftdnirlfwPPkmgqakkyqdltvehslekeen.dyqiitlel
TNDNKAGdkQQVKQYQITNWDSTGKltNPQTILLVIEEMYRTQRKRGNTSIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQT
|.. ..| | .|. . | . .. . . | . || .|..||| ||||| | . . ... ||||| |.|. |. | |..| |.|
kfknesa..hnvtlyyykkwnintn..nkpylkplfgilaknqlengnrPlvvacsdGvGrsGtflvidsqleraktegvsdifdflrkirsqriglvdt
VQQYQGIFQIVLT
..| | ...
keryiyihellae
|
|||||||||
| subfamily_PTPN12_pd | Subfamily PTPN12 | 978-1095 | 3.2e-32 | 106.6 | In-house | 31-148 (290) | alignment | ||
Range on Protein: 978-1095
Range on HMM: 31-148/290.0
TVTVGLTPSNKLLNRFANIVVYDDNRITLRPMPGHKdcTNEYINACFIKDYSNQYQYIATQGPVSNTLVDFWQLIWQEKSTIIVMITNIIEEGKVKCQQY
. ..| ...|. ||. .|. || .|..|. . ... ..|||| ||| ... .|||.|||...|| |||..||. . .|.||. ...| || ||..|
steagekeenvkknrykDilPydksrvelskieeee..gsdYinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCerY
WPNSDTK--DYGPFSVTLRE
||.. . .|.|.||| |
Wpeegeeelefgefevtlee
|
|||||||||
| subfamily_PTPN3_pd | Subfamily PTPN3 | 966-1094 | 4.1e-32 | 106.2 | In-house | 20-147 (280) | alignment | ||
Range on Protein: 966-1094
Range on HMM: 20-147/280.0
QFGMLDSGESDHTVTVGLTPSNKLLNRFANIVVYDDNRITLRpmpghkDCTNEYINACFIKDYSN----QYQYIATQGPVSNTLVDFWQLIWQEKSTIIV
|| .| . . .... | | ||. .|. ||. |..|. . ...|||| ... .. .|||||||...| ||||..|..||..||
qfeqlyrkkpglaisaarkpenlsknryrdilpydatrvklk......esetdyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqkssliv
MITNIIEEGKVKCQQYWPN-SDTKDYGPFSVTLR
|.|...|.|.||| ||||. .|. .|| |||...
mlttlverGrvkChqyWPetedeleygefsvkce
|
|||||||||
| subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 945-1094 | 4.2e-32 | 106.5 | In-house | 7-154 (325) | alignment | ||
Range on Protein: 945-1094
Range on HMM: 7-154/325.0
VDKFGEFVANGHAKGNEGFRNQFGMLDSGESdHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMpgHKDCTNEYINACFIKDYSNQYQYIATQGPVSNT
| .. |.| . .|. ..|| ..||.| | .. . .| | || ||| |.| .| .|. | . ..| .|||| ...|. .. ..|.| | ..|
vvnlvehvekkkaqdqdgfahefgllpsddg.iakkvamkpenkaknrfknvvaldksrvvletk..kddpssdyinasylrddkkkdvflaaqaPltat
LVDFWQLI--WQeksTIIVMITNIIEEGKVKCQQYWPNS--DTKDYGPFSVTLR
. |.|.|. |. . .|...|....|| .| .|||. ..| .|.. | ||
indlWrlvldWr...csvvvvlneldlgkdrcavywpkemgksktfGglevklr
|
|||||||||
| subfamily_PTPN13_pd | Subfamily PTPN13 | 1091-1304 | 1.1e-31 | 105.1 | In-house | 54-271 (273) | alignment | ||
Range on Protein: 1091-1304
Range on HMM: 54-271/273.0
VTLREHPDYINAVFINGY--KEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSNRK---LGEYN-ISLLNEEI-HNAGYIER
|.| .. |||| .|. |.. .|.. |. .|...||.|. ..... |.|. .| ... | .|| ..| | .| . . .... . |. |
vklgdeggyinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvkchrywPesknkklkvsnrlevellkvqkldgfvvr
KIEVtNDNKAGDKQQVKQYQITNWDSTGKLTNPQTILLVIEEMYRTQRkrGNTSIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRIQKPG
...| .|...|. ..| . . ..| | .... .| .. |. | |. .. ||.||| .||||.. . . .. . . .|| ..... | |. |
alav.kdsesgesrevahlnfvkwPdhgvPssaaellqfvaevrrlqt..dagPivvhcsaGiGrsGtlitidvvlglierdkefdvkeivrklreqrqg
SVQTVQQYQGIFQIVLTYLDS
||| .|| .....|. | |
vvqtkdqyifvykailevlks
|
|||||||||
| 0042113 | (Phosphotyrosine protein) phosphatases II | 981-1095 | 1.8e-31 | 104.8 | In-house | 3-115 (245) | alignment | ||
Range on Protein: 981-1095
Range on HMM: 3-115/245.0
VGLTPSNKLLNRFANIVVYDDNRITLRPMPGHKDCTneYINACFIKDYSNQYQYIATQGPVSNTLVDFWQLIWQEKSTIIVMITNIIEEGKVKCQQYWPN
|.| | || .||. .|. ||..|. | |..|. |.. ||||.... | ..|||||| ..|. |||...|....|.|||.|. | |.|||.||||.
vallpenkdknrysdilpydhtrvklspdggdldsd..yinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywpl
SDTKDYGPFSVTLRE
.... || |.|||..
gesltygdftvtlls
|
|||||||||
| 0051429 | (Phosphotyrosine protein) phosphatases II | 1096-1305 | 2e-31 | 105.0 | In-house | 3-228 (272) | alignment | ||
Range on Protein: 1096-1305
Range on HMM: 3-228/272.0
HPDYINAVFINGYKE---KKAFIIAESPMFNTARNFWKMiDDRNVTAIVMLCQENKNNQEVCYQYWSNRKLGEYNISLLNEE--------------IHNA
..|||| ...|| ..... . |. .||..||.. . ....||.|..|. ... |..|| . .. ..| .. ..
lsgyiNardvggygrvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseelll
GYIERKIEVTNDNKAGDKQQVKQYQITNWDSTGKLTNPqtILLVIEEMYRtqrkrgNTSIVIHCSDTVGRSGVFCAAATTINKCKTEGVID--------V
|| |....|. .||. .| ... |.| | ... .| ..|.. . . ...||| ..|.|...|. . | ..| .
dyilrellltlllsagearevmhlhytdwpdhgvpqea..llellellld......ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlyl
FQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYLDSF
..... | | ||.||| .||. .....| .|.|.
eeaveelraqrpgavqteeqylflyeallellrsl
|
|||||||||
| subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 943-1093 | 8.6e-31 | 101.9 | In-house | 3-150 (315) | alignment | ||
Range on Protein: 943-1093
Range on HMM: 3-150/315.0
IPVDKFGEFVANGhaKGNEGFRNQFGMLDSGESdHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMpgHKDCTNEYINACFIKDYSNQYQYIATQGPVS
||| .| || . . | ..| | . . .|. .. | ||. ||. .| .|. | . .. ..|||| .|| . .. |||.|||
ipvaqfpafvnkn..rhtalfseefhdlpdPdi.yrqrvaretinfkknryknilPldsarvklevi..ddsPdsdyinasyiksvdddkayiasqgPlk
NTLVDFWQLIWQEKSTIIVMITNIIEEGKVKCQQYWPN--SDTKDYGPFSVTL
.. |||....||| | |||.|. |. |.||.||||. .|. ..| ..|.|
asvddfwrmvlqekvttivmvtkkqegdkikcrqywPdrkadsvefGsikvel
|
|||||||||
| subfamily_PTPN23_pd | Subfamily PTPN23 | 959-1095 | 1e-30 | 101.6 | In-house | 13-148 (288) | alignment | ||
Range on Protein: 959-1095
Range on HMM: 13-148/288.0
GNEGFRNQFGMLDSGESDHTV--TVGLTPSNKLLNRFANIVVYDDNRITLRpmpghkDCTNEYINACFIKDYSNQ-YQYIATQGPVSNTLVDFWQLIWQE
|. .. ..| |.. . .. .. . . ||. .|. || ||..|| . ...||||.|.|| | . ..||||.| .|| |||......
gktaldkkfkeleqkqdkearkrsiaiaklyseknrsrdilPyDhnRvklr......gskDDYinAsfvkdlspgcPdfiatqaPlqstlnDFWlmvyeq
KSTIIVMITNIIEEGKVKCQQYWPNS--DTKDYGPFSVTLRE
|| .|||... | || |...|||.. .|. .|..||||..
kssviVmllskeelgkpkvdrYwPedkgetvkfgdlsvtlks
|
|||||||||
| subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 986-1094 | 2.1e-30 | 100.7 | In-house | 2-108 (237) | alignment | ||
Range on Protein: 986-1094
Range on HMM: 2-108/237.0
SNKLLNRFANIVVYDDNRITLRPMPGHkdctNEYINACFIKDYSN-QYQYIATQGPVSNTLVDFWQLIWQEKSTIIVMITNIIEEGKVKCQQYWPNSDT-
||. ||..|||.|| .|. |. . .||||...|.. .|||.|||. .. ||||..|||| ..|||.| .|| ..|| .|||..|
enkiknrygnivaydhsrvvlkgagsg....sdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpstdqp
KDYGPFSVTLR
. || ..|.|.
aaygvltvslk
|
|||||||||
| subfamily_PTPN14_pd | Subfamily PTPN14 | 976-1092 | 2.5e-30 | 100.5 | In-house | 38-157 (300) | alignment | ||
Range on Protein: 976-1092
Range on HMM: 38-157/300.0
DHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMpghKDCTNEYINACFIKDY--SNQYQYIATQGPVSNTLVDFWQLIWQEKSTIIVMITNIIEEGKVK
| ..... | |. ||| ... |.|||. | | |. ...|||| || .....||..|||. .|. ||||..|... ..|||.|...|.|| |
dallstaklpenaeknrfkdvlPyednrvelspt...kenstgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivmlteeeedgkek
CQQYWPNS----DTKDYGPFSVT
. .|.|.. .| ..| | ||
sfkyfPkleskkktvefgkfkvt
|
|||||||||
| subfamily_PTPN1_pd | Subfamily PTPN1 | 1094-1297 | 5e-30 | 99.2 | In-house | 53-266 (290) | alignment | ||
Range on Protein: 1094-1297
Range on HMM: 53-266/290.0
REHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWS--NR----KLG--EYNISLLNEEIHNAgYIERKI
|.. ||||| ... . |. .|.. |. ||. ||.|. ... |.||| . ..| |.||| .. .| .... |..||... |. |..
radndyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvvekeqikcaqywPqgeeekellledtklkvkliseerksy.ytvrll
EVTNdNKAGDKQQVKQYQITNWDSTGKLTNPQTILLVIEEMYRTQR-KRGNTSIVIHCSDTVGRSGVFCAAATTIN---KCKTEGVIDVFQVLKSQRIQK
|..| |. . ... .. | | | |.. | . .. .. .. ||||| .|||| || . | . | . .|. .|| | ..
elen.lktqetreilhfhyttwpdfgvpespaaflkflfkvresGslssdvGpavihcsaGiGrsGtfclvdtclvliekkddlssvdikkvllelrkyr
PGSVQTVQQYQGIFQI
| .|| .| . ..
lGliqtadqlrfsyla
|
|||||||||
| subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 980-1093 | 1.1e-29 | 98.8 | In-house | 54-159 (319) | alignment | ||
Range on Protein: 980-1093
Range on HMM: 54-159/319.0
TVGLTPSNKLLNRFANIVVYDDNRITLRPMPGHKdcTNEYINACFIKDYSNQYQYIATQGPVSNTLVDFWQLIWQEKSTIIVMITniieegKVKCQQYWP
| . || ||. ||. .| |.. |... | .|||| |.. | .. .|||.||| ||| |||..||. ... ||..| | || ||||
tfanldqnkdknriinilafdknvvklerliGee..fsdyinasfvtGyqrkdkyiaaqGPldntladfWrmiweyncstivllt......kdkcsqywp
NSDTKDYGPFSVTL
. . .. | | .
lkivikeerfkvkv
|
|||||||||
| subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 980-1093 | 1.6e-29 | 98.3 | In-house | 18-123 (284) | alignment | ||
Range on Protein: 980-1093
Range on HMM: 18-123/284.0
TVGLTPSNKLLNRFANIVVYDDNRITLRPMPGHKdcTNEYINACFIKDYSNQYQYIATQGPVSNTLVDFWQLIWQEKSTIIVMITniieegKVKCQQYWP
| . || ||. .|. .| |.. |... | .|||| ||. | .. .||||||| ||| |||..||. ... ||..| | || ||||
tfanldqnkdknrighilafdknvvklerliGee..fsdyinasfitGyqrkdkyiatqGPldntladfWrmiweyncstivllt......kdkcsqywp
NSDTKDYGPFSVTL
. . .. | | .
lkivikeerfkvkv
|
|||||||||
| 0050432 | (Phosphotyrosine protein) phosphatases II | 19-147 | 4.1e-29 | 97.3 | In-house | 163-288 (308) | alignment | ||
Range on Protein: 19-147
Range on HMM: 163-288/308.0
MILGEYNIILLNEETFNGYIERKFEVKNNNTGATQSVTQYQITNWDSTGKLTNPQTILLVIEEMYRTQrkrGNTSIVVHCSDTVGRSAMFCAAATTINKC
.. | . . ||.||....|. |..|..|...| . ||... ||| | ..|. .| .|.. ... .. ||||||. |||.. |.|. . ..
leygkftvtllseevlddytvrtleltnlgdgesrtvthfhytnWpdhgvPpspeilldflelvrksl...pggpivVHCsaGvGRtGtfialdllleql
KTEGVIDVFQVLKSQRIQKPGSVQTVDRI
..|| .|||...| | |.||.|||..
ekeggvdvfeavkklReqRpgmvqtpeqy
|
|||||||||
| 0041856 | (Phosphotyrosine protein) phosphatases II | 1085-1301 | 8.5e-29 | 95.8 | In-house | 9-170 (182) | alignment | ||
Range on Protein: 1085-1301
Range on HMM: 9-170/182.0
DYGPFSVTLreHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCqenknnqevCYQYWSNRKlgeynisllneeihnagyierk
|. |. .. ..||||| .. |. . ||.. |. .| .|..|. ....|.||.|. ...|| ..
dilpydhsr..dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt.........eelywpell......................
ievtndnkagdKQQVKQYQITNWDSTGKLTnPQTILLVIEEMYRtqrkrGNTSIVIHCSDTVGRSGVFCAAATTINKckteGvIDVFQVLKSQRIQKPGS
.... ||. ..|. | . ....| |||... . ...||| |||.|...|| . . | .......| | ..||.
...........erlgiqylylpwpDhgvpd.ldelldfieevle.....eggpvlVHCsaGvgRtgtlvaaylmkkl....g.vsleeavklvrsrRpgm
VQTVQQYQGIFQIVLTY
|.| .||. . ...| .
vitpnqyfflqlallel
|
|||||||||
| subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 987-1095 | 1.2e-28 | 94.9 | In-house | 7-113 (239) | alignment | ||
Range on Protein: 987-1095
Range on HMM: 7-113/239.0
NKLLNRFANIVVYDDNRITLRPMpgHKDCTNEYINACFIKDYSNQ-YQYIATQGPVSNTLVDFWQLIWQEKSTIIVMITNIIEEGKVKCQQYWPNSDTKd
|| ||.|||| || .|. | . .| ..|||| ...|| |||||| |. . |||...|||. .|||.| .|| | ||.||||.| .|
nkaknryanivtydhsrvvlekl..sndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdstsk.
YGPFSVTLRE
| . ||||.
ycnlrvtlrk
|
|||||||||
| subfamily_PTPRD_pd | Subfamily PTPRD | 21-146 | 1.3e-28 | 94.9 | In-house | 145-269 (564) | alignment | ||
Range on Protein: 21-146
Range on HMM: 145-269/564.0
LGEYNIILLNEETFNGYIERKFEVKNNNTGATQSVTQYQITNWDSTGKLTNPQTILLVIEEMYRTQrKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKT
||. . | .||... |. |.|..|.... .. |.|.. |.| ..| ......| .|... ... .... |||||| |||. .|.. ... |.
ygeltVtleeeeeladyeirtfklkkkkssesreVrqFhFtsWPdhgvpesatslLdlirkvraln.epdagPivVhCSaGVGRTGtfividamlerike
EGVIDVFQVLKSQRIQKPGSVQTVDR
|...|..|..| | |.. ||| .
ektvDiyqyvkalrkqRnamVqteeQ
|
|||||||||
| subfamily_PTPN13_pd | Subfamily PTPN13 | 976-1084 | 1.3e-28 | 95.1 | In-house | 26-129 (273) | alignment | ||
Range on Protein: 976-1084
Range on HMM: 26-129/273.0
DHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMPGhkdctneYINACFIKDY--SNQYQYIATQGPVSNTLVDFWQLIWQEKSTIIVMITNIIEEGKVK
|..|| . .|| ||. |.. ||. |..| | |||| .|| ..|.|||.|||. .| ||||..|. |...|.|.|. |.||||
ldtcevgkkkenkdknryrnvlPydetrvklgdegg.......yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvk
CQQYWPNSDTK
|..|||.| |
chrywPesknk
|
|||||||||
| subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 987-1095 | 1.3e-28 | 94.7 | In-house | 8-114 (239) | alignment | ||
Range on Protein: 987-1095
Range on HMM: 8-114/239.0
NKLLNRFANIVVYDDNRITLRPMpgHKDCTNEYINACFIKDYSNQ-YQYIATQGPVSNTLVDFWQLIWQEKSTIIVMITNIIEEGKVKCQQYWPNSDTKd
|| ||.|||| || .|. | . .| ..|||| ...|| |||||| |. . |||...|||. .|||.| .|| | ||.||||.| .|
nkaknryanivtydhsrvvlekl..sndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdstsk.
YGPFSVTLRE
| . ||||.
ycnlrvtlrk
|
|||||||||
| 0037934 | (Phosphotyrosine protein) phosphatases II | 980-1094 | 2e-28 | 95.0 | In-house | 3-108 (243) | alignment | ||
Range on Protein: 980-1094
Range on HMM: 3-108/243.0
TVGLTPSNKLLNRFANIVVYDDNRITLrpmpghKDctNEYINACFIKDYSNqyqYIATQGPVSNTLVD----FWQLIWQEKSTIIVMITNIIEEGKVKCQ
...| | |. ||. .|. ||..|. | .. . |||| .|. . . .|||||| ..|. | ||...|....|.|||.|. .| |..||
siallpenlsknrysdilpydhsrvkl......eg..sdyinanliyvtpr...liatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekca
QYWPnsDTKDYGPFSVTLR
|||| ... ||.|.|||
qywp..gevtygdftvtll
|
|||||||||
| 0046845 | (Phosphotyrosine protein) phosphatases II | 19-148 | 4.5e-28 | 93.9 | In-house | 130-264 (284) | alignment | ||
Range on Protein: 19-148
Range on HMM: 130-264/284.0
MILGEYNIILLNEETFNGYIERKFEVKNNN-TGATQSVTQYQITNWDSTGKLTNPQTILLVIEEMYRTQRK-RGNTSIVVHCSDTVGRSAMFCAAATTIN
...|.. . ||.||....|. |..|..|.. || . ||....|.| | ..|. .| .... . ... |. ||||||. |||...|.|. . ..
ltygdftvtllseevkddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrellenlpgggpivVHCsaGvgRtGtfialdllle
KCKTEG---VIDVFQVLKSQRIQKPGSVQTVDRII
..|| ..||....| | |.||.|||.. ..
qlekeglllgvdvleavkrlreqRpgmvqtleqyr
|
|||||||||
| 0036941 | (Phosphotyrosine protein) phosphatases II | 17-145 | 5.2e-28 | 93.6 | In-house | 130-264 (297) | alignment | ||
Range on Protein: 17-145
Range on HMM: 130-264/297.0
SGMILGEYNIILLNEET--FNGYIERKFEVKNNNTGATQSVTQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKR-GNTSIVVHCSDTVGRSAMFCAAAT
. . |.. . ||..|. ...|. |..||.....| . ||....|.|. | ..|...| ||.. . ... ... ..||||. ||||..|.|| .
esltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrkvlkllpsggpvlVHCsaGvgRsgtfiaadl
TINKCK---TEGVIDVFQVLKSQRIQKPGSVQTVD
.. . .|| .|.....|. | |.||.|||..
mlqqledklkeggvdileavkklReqRpgavqtle
|
|||||||||
| subfamily_PTPRN_pd | Subfamily PTPRN | 1095-1298 | 5.2e-28 | 92.6 | In-house | 82-288 (297) | alignment | ||
Range on Protein: 1095-1298
Range on HMM: 82-288/297.0
EHPDYINAVFINGYKEK-KAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSNR---KLGEYNISLLNEEIHNAGYIERKIEVTND
|. ||||| .| . |.| ...|. .| .||.|. .. |. ||.|.. .... . |..|| . . |.. |. | | |. | . . |
eksdyinasaildhdprapayiatqgplastvadfwqmvweqGvvvivnltrleeegvkqckrywpdeGsevyhiyevhlvsehiwcddylvrsfylknl
nKAGDKQQVKQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKRGnTSIVIHCSDTVGRSGVFCAAATTINKC-KTEGVIDVFQVLKSQRIQKPGSVQTVQ
.. . . | |. | ..| ......| . .. | | ..||.|||| .||.||... .|. | ||. |. | |.|| |.| .
.qtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrGrs.cpivvhcsdGaGrtGvyilidlvlnrllkGvkeidiaatlehlrdqrpglvktkd
QYQGIFQIV
|.. ... |
qfefaltav
|
|||||||||
| subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 988-1091 | 5.3e-28 | 92.9 | In-house | 29-136 (274) | alignment | ||
Range on Protein: 988-1091
Range on HMM: 29-136/274.0
KLLNRFANIVVYDDNRITLRPMPGHkDCTNEYINACFIKDYSNQY-QYIATQGPVSNTLVDFWQLIWQEKSTIIVMITNIIEEGKVKCQQYWPNSDTK--
. ||. .|. . |..|.. .. | .|||| .|| |... |.|||||..||. |||..|.||....|||.|.. |. . ||..|.|..
qtknryktilPnensrvllesesse.dedssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneqkCavyfPdaedyei
--DYGPFSV
|| ...
serygdvei
|
|||||||||
| 0047943 | (Phosphotyrosine protein) phosphatases II | 19-147 | 6.8e-28 | 93.3 | In-house | 132-261 (273) | alignment | ||
Range on Protein: 19-147
Range on HMM: 132-261/273.0
MILGEYNIILLNEETFNGYIERKFEVKNNNTGATQSVTQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKR-GNTSIVVHCSDTVGRSAMFCAAATTINK
.. |.. . ||.|||...|. |..|..|..|| . ||... |.| | .... .| ||.. ..... .|. .|||||. |||...|.|. . ..
ltygkftvtllseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvrkalealpsngpvvVHCsaGvgRtgtfialdllldq
CKTEGVIDVFQVLKSQRIQKPGSVQTVDRI
..|| .||....| | |.||.|||.. .
lekeggvdvleavkllrsqRpgmvqtpeqy
|
|||||||||
| subfamily_PTPN1_pd | Subfamily PTPN1 | 972-1084 | 8e-28 | 92.0 | In-house | 17-123 (290) | alignment | ||
Range on Protein: 972-1084
Range on HMM: 17-123/290.0
SGESDHTVTVGLTPSNKLLNRFANIVVYDDNRITLrpmpghKDCTNEYINACFIKDYSNQYQYIATQGPVSNTLVDFWQLIWQEKSTIIVMITNIIEEGK
||..... .|.|. |||. .. || ||.| .. |.|||| ... . .|| ||||..|| |||..|..|| .||. ...|...
keasdfptreaklpenrnlnryrdvspydhsrikl......eradndyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvvekeq
VKCQQYWPNSDTK
.||.||||. . .
ikcaqywPqgeee
|
|||||||||
| subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 982-1083 | 8e-28 | 92.2 | In-house | 15-115 (270) | alignment | ||
Range on Protein: 982-1083
Range on HMM: 15-115/270.0
GLTPSNKLLNRFANIVVYDDNRITLRPMpgHKDCTNEYINACFIKDY-SNQYQYIATQGPVSNTLVDFWQLIWQEKSTIIVMITNIIEEGKVKCQQYWPN
. .| |||.|.|. |..| .. ..| . .|||| ... . ... .|||..||. .|| .||..||.||.| |||.|.. |.|. ||..|||.
peaargkklnRyadiLPsPatRvrleel..eedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpa
SDT
.
epk
|
|||||||||
| 0043147 | (Phosphotyrosine protein) phosphatases II | 1095-1295 | 9.3e-28 | 92.5 | In-house | 3-154 (172) | alignment | ||
Range on Protein: 1095-1295
Range on HMM: 3-154/172.0
EHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQEnknnqevcyqywsnrklgeynisllneeihnagyierkievtNDNKAG
|. ||||| ....| . ||. |. || ||.|. ....|.||.|... .. .
egsdyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltel..........................................lydpel
DKQQVKQYQITNWDSTGKLtNPQTILLVIEEMYRTQRKRGNTSIVIHCSDTVGRSGVFCAAATTInkckteG-ViDVFQVLKSQRIQKPGSVQTVQQYQG
.... ||. ..|. | ... .| ..| ... . .. . ...||| |||.|...|| . . ....... | ..||.||. .||.
lerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml......lgl.sleeavalvrekRpgavqnpsqyrf
IF
.
ly
|
|||||||||
| subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 943-1093 | 1.2e-27 | 91.8 | In-house | 10-152 (297) | alignment | ||
Range on Protein: 943-1093
Range on HMM: 10-152/297.0
IPVDKFGEFVANGHAkgNEGFRNQFGMLdsGES-DHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMpgHKDCTNEYINACFIKdySNQYQYIATQGPV
||. .| .| ... . |...| | |. .. || | .|..||. || .|..|. . .| .|.|| |.| .|....|.|| |
iplsdfatlvqknrh..tdvfseeflcl..peaniqpqtvaekkvnfeksRYkniLPydssRvkLaiv..nddpdsDyvnasfvk..gnkhrlittqmPm
SNTLVDFWQLIWQEKSTIIVMITNIIEEGKvKCQQYWPNSDTKDYGPFSVTL
.|. |||.....|. ..|||... |. | ||..||... .. .| ||.|
katvadfWamvldeqvstivmlnddnerdk.kcaryWsdkgvttfGdvsvvl
|
|||||||||
| subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 22-153 | 1.4e-27 | 91.8 | In-house | 154-285 (298) | alignment | ||
Range on Protein: 22-153
Range on HMM: 154-285/298.0
GEYNIILLNEETFNGYIERKFEVKNNNTGATQSVTQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTE
|| .. ||..|.| .| ||..|..... ...| | . |.| . | .| ...| ..... ..|.. ||....|.||. |||| |.| . ... |.|
geitvsllskeefadlivrklkvskkkeekerevrqlhftsWpdkgvpenatsvldllrkvrasqqqagnkpvivqCsaGvgRsGtfiaidsvlervkke
GVIDVFQVLKSQRIQKPGSVQTVDRIIPDYFM
|.|||||.| |...||.||| .. . | .
qvvDvfqvvkvlRkkrpgavqteeqYvfiyea
|
|||||||||
| subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 1095-1302 | 2.1e-27 | 90.5 | In-house | 71-236 (392) | alignment | ||
Range on Protein: 1095-1302
Range on HMM: 71-236/392.0
EHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNqevcyqywsnrklgeynisllneeihnagyierkievtndnKAG
. ||.|| .|.... .||.| ...| . .||.|. . |||.|.|. . .. . |
pdsdylnasyipsfdnekayiasqgpnaaslddfwrmvfqenvttiamvtklkegd.........................................kgd
DKQQVKQYQITNWDSTGKLTNPQTILLVIEEMyrtQRKRGNTS--IVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQ
|.. | |...|.| . ..| .|.|. . . |. . ..|||| |||.|| . . . ..|. ..|||... | ..| ||| .||
dartvaqfhftewPdkdvpkhtssllkfikev...kadfGqythpliihcsagvgrtgvvisidsvvahakktrmvdvfnfvtnirrkrpymvqtkeqya
GIFQIVLTYL
|. || |
fiygavledl
|
|||||||||
| subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 24-183 | 2.2e-27 | 91.0 | In-house | 146-307 (318) | alignment | ||
Range on Protein: 24-183
Range on HMM: 146-307/318.0
YNIILLNEETFNGYIERKFEVKNNNTGATQSVTQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGV
. | .| ... |. |.|.|..... ... | ||..|.| .| .... ..| .. . ..|.| |.. |||||| ||| .|.| . ... | |..
lvvelkeevelsdyvlrefkvtrteeeesrqvrqyhytsWpdegvpesgaslldlvrqvskaqqksgagpivvhCsaGvGrtGvfiavdillerikaeal
IDVFQVLKSQRIQKPGSVQTVDRI--IPDYFMIYASQFYDKDENDDVNDTIDALWCQSANNG
.||||. | | |.. ||| |. | | . . . . . .|... | | |... |
vDvfqtvkqlreqrnlmvqtedqyefiydvllealasgdtevdasdlrsrirelreqdpesg
|
|||||||||
| 0051299 | (Phosphotyrosine protein) phosphatases II | 19-146 | 3.1e-27 | 91.2 | In-house | 144-274 (288) | alignment | ||
Range on Protein: 19-146
Range on HMM: 144-274/288.0
MILGEYNIILLNEETFNGYIERKFEVKNN----NTGATQSVTQYQITNWDSTGKLTNPQTILLVIEEMYRTQRkRGNTSIVVHCSDTVGRSAMFCAAATT
...|.. . ||.||....|. |..||.|. .| .. ||... ||| | ..|. .| ...... .. |. .|||||. |||...|.|. .
ltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdspellldflrlvrkala.sgggpvvVHCsaGvgRtgtfialdll
INKCKTEGVIDVFQVLKSQRIQKPGSVQTVDR
.. ..||..||....| | |.||.|||..
leqlekeggvdvleavkrlreqRpgmvqtpeq
|
|||||||||
| subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 1097-1299 | 3.9e-27 | 90.0 | In-house | 29-236 (237) | alignment | ||
Range on Protein: 1097-1299
Range on HMM: 29-236/237.0
PDYINAVFINGYKE-KKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSN----RKLGEYNISLLNEEIHnAGYIERKIEVTNDN
||||| ...|. | .| |. |. .. .||.|. . . . |||| ..|.. |..|| . . | . .|| .| . | | . ...
sdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpstdqpaaygvltvslkkkeef.sdytvrslllskrl
KAGDKQQVKQYQITNWDSTGKLTNPQTILLVIEEMYRTQRK-RGNTSIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQ
. . . ..|||.| | | . ..| .. .. . .|||| |||.|.| . . ..| . |.|... ..| ..| .|| .|
tlkevrlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlrqakekkvvdiynyvysieedrpyiiqtkdq
YQGIFQIVL
| |.| .|
yvfihqtil
|
|||||||||
| 0040438 | (Phosphotyrosine protein) phosphatases II | 19-146 | 4.3e-27 | 90.6 | In-house | 138-264 (317) | alignment | ||
Range on Protein: 19-146
Range on HMM: 138-264/317.0
MILGEYNIILLNEETFNGYIERKFEVKNNNTGATQSVTQYQITNWDSTGKLTNPQTILLVIEEMYRTQRkRGNTSIVVHCSDTVGRSAMFCAAATTINKC
. |.. . ||.||. .|.. |..||...... . ||... |.|. | .|...| .|.. . .. .... ..||||. |||...|.|| . .. .
ltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavreale.dpggpvlVHCsaGvgRtGtfiaaylmleql
KTEGVIDVFQVLKSQRIQKPGSVQTVDR
..|| .||....| | |.||.||| .
ekeggvdveeavkelreqRpgavqtpeq
|
|||||||||
| subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 977-1093 | 5e-27 | 89.2 | In-house | 33-149 (515) | alignment | ||
Range on Protein: 977-1093
Range on HMM: 33-149/515.0
HTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMpgHKDCTNEYINACFIKDYSNQYQYIATQGPVSNTLVDFWQLIWQEKSTIIVMITNIIEEGKVKCQQ
. || | ||. ||. || .|. | . . . ..|.|| .|. . |. |||.||| .. |||.|..||. | |.|.|. |. |.|| .
ypqtvaqeeinfkknryknilPydsvrvklevi..ndnPhsdyfnasyipsfdndkayiasqgPnkasvddfWrlvlqenvttiamvtklkegdkikcgk
YWPN--SDTKDYGPFSVTL
|||. .|. .| ..| |
yWPdkpgdsvkfGsikvel
|
|||||||||
| subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 21-146 | 1.4e-26 | 88.0 | In-house | 129-254 (283) | alignment | ||
Range on Protein: 21-146
Range on HMM: 129-254/283.0
LGEYNIILLNEETFNGYIERKFEVKNN-NTGATQSVTQYQITNWDSTGKLTNPQTiLLVIEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCK
||. . | .| | | .| ... ...| . .| .. ||. .| . |. . . |. .. . |.. .. |||||| ..||.|.|.||...... .
yGeftvtlrkettsnsfiikelllrvnssakstlllahyqvidWleygeqaiins.lvkfnkvislqteskkgPivvhCstgiGrtavfiaasasvkdal
TEGVIDVFQVLKSQRIQKPGSVQTVDR
|| |.|||.|.| | |... ||| |.
tesvvdvfavvkimreqrmmavqtldq
|
|||||||||
| 0049260 | (Phosphotyrosine protein) phosphatases II | 1104-1295 | 1.5e-26 | 88.3 | In-house | 1-143 (152) | alignment | ||
Range on Protein: 1104-1295
Range on HMM: 1-143/152.0
FINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWsnrklgeynisllneeihnagyierkievtndnkagdkqqvkQYQ
||.||. ...||... |. ||. .||.|. . ..|.||||... .. . |.||. ||.
fidgyampfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi..........................................qyl
ITNWDSTGKLTNPQTILLVIEEMYRTqRKRGNTSIVIHCSDTVGRSGVFCAAATTInkckteGVIDVFQVLKSQRIQKPGSVQTVQQYQGIF
..|. | ...| .| ... . . ... . ...||| |||.|...|| . ........ | ..||.|.. .|.. ..
hlpwpDhgvpdlsqlllflllfiekl.aldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpgqlrfly
|
|||||||||
| 0046846 | (Phosphotyrosine protein) phosphatases II | 1093-1303 | 1.6e-26 | 88.6 | In-house | 8-174 (176) | alignment | ||
Range on Protein: 1093-1303
Range on HMM: 8-174/176.0
LREHPDYINAVFINGYKekkaFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSNrkLGEYNIsllneeihnagyierkievtndnk
|....||||| .| |.. .|. |. .| .|..|. . ..||.|.|..| .. |..||. | ...|
ldldldyinanlilgsr....piatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpe..leklgi........................
agdkqqvkQYQITNWDSTGKLTNpQTILLVIEEMYRTQRKrGnTSIVIHCSDTVGRSGVFCAAAttinKCKTEGVIDVFQVLKSQRIQKP-GSVQTVQQY
||. ..|. | . . .| ..|.... ... | ...||| .||.|...|| ...| ..|...|. | |.| |.||| .||
........qylhlpwpDhgvpdl.elllellefirealke.g.gpvlVHCsaGigRtgtlvaay....llelekglsveealalvreqRplgavqtpeQy
QGIFQIVLTYLD
. . . .| .|.
rflyefellllk
|
|||||||||
| subfamily_PTPRN_pd | Subfamily PTPRN | 974-1093 | 1.8e-26 | 87.5 | In-house | 42-161 (297) | alignment | ||
Range on Protein: 974-1093
Range on HMM: 42-161/297.0
ESD-HTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMPGHKdcTNEYINACFIKDYS-NQYQYIATQGPVSNTLVDFWQLIWQEKSTIIVMITNIIEEGK
|.. .| .|. .. | || .... ||..|..|. .. ...|||| .| | . |||||||...|. ||||..|.. ...||..|.. |||
eaepstkevakaeknvkknrskavlpydhsrvklkeeasae..ksdyinasaildhdprapayiatqgplastvadfwqmvweqGvvvivnltrleeegv
VKCQQYWPNSDTKDYGPFSVTL
.|..|||. .. |. . | |
kqckrywpdeGsevyhiyevhl
|
|||||||||
| subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 22-183 | 5.5e-26 | 86.4 | In-house | 146-310 (319) | alignment | ||
Range on Protein: 22-183
Range on HMM: 146-310/319.0
GEYNIILLNEETFNGYIERKFEVKNNNTGA-TQSVTQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKT
|.. . |..|| ..|| ||........ | .|...| |.| . .. ...| ..... ....| . ||||||. ||| |.. .... |
GrlivtleeeeeledyiirklklnkkssevetRevkhfqyteWpdhdvPekatslldllkrirksrektqsgPivvhCsaGvGRtGtfivldamlervke
EGVIDVFQVLKSQRIQKPGSVQTVDR--IIPDYFMIYASQFYDKDENDDVNDTIDALWCQSANNG
|||.|||.. . |.|.. ||. . .| . . ... . . | .|..| . .| . |. |
egvlDvfstvsrlRtqRnimvqrpeqYkfiyealleaveagdteievqdlrdrlkqlaekvadtg
|
|||||||||
| subfamily_PTPN14_pd | Subfamily PTPN14 | 1096-1303 | 7.8e-26 | 85.7 | In-house | 75-297 (300) | alignment | ||
Range on Protein: 1096-1303
Range on HMM: 75-297/300.0
HPDYINAVFING--YKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSNR-------KLGEYNISLLNEEiHNAGYIERKIE
. .|||| |. ... .|.| .|. .| ..||.|. . .|. |||| .|... .| ...|. . . |..... | . .| ....
stgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivmlteeeedgkeksfkyfPkleskkktvefgkfkvttkfse.dsdsvittglk
VTNdNKAGDKQQVKQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKRGNT--------SIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQR
. ......| | |.| | .... | .||. .|| .. ...|||. |||.|| . |. ... .||. .||. |
lkh.lpskeertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseveskeskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLr
IQKPGSVQTVQQYQGIFQIVLTYLD
|. |||. ||. .......||.
eqrmllvqtlaqYkfvYkvlikylk
|
|||||||||
| Y_phosphatase | Protein-tyrosine phosphatase | 22-146 | 1e-25 | 85.9 | Pfam-A | 99-225 (235) | alignment | ||
Range on Protein: 22-146
Range on HMM: 99-225/235.0
GEYNIILL-NEETF-NGYIERKFEVKNNNTG-ATQSVTQYQITNWDSTGKLTNPQTILLVIEEMYRTQrKRGNTSIVVHCSDTVGRSAMFCAAATTINKC
|.... | .|.. ..|. ||.|.|.... ....|.|...||| | ..|. .| .|... ... . ....|||||. |||...|.|. . ....
gdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkveksk.eaksgpvvVhCsaGvgRtgtfvaldilleql
KTEGVIDVFQVLKSQRIQKPGSVQTVDR
..|. .||.|..|. | |.||.||...
eaeeevdvlqivkelRkqRpgmvqsleq
|
|||||||||
| Y_phosphatase | Protein-tyrosine phosphatase | 22-146 | 1e-25 | 85.9 | In-house | 99-225 (235) | alignment | ||
Range on Protein: 22-146
Range on HMM: 99-225/235.0
GEYNIILL-NEETF-NGYIERKFEVKNNNTG-ATQSVTQYQITNWDSTGKLTNPQTILLVIEEMYRTQrKRGNTSIVVHCSDTVGRSAMFCAAATTINKC
|.... | .|.. ..|. ||.|.|.... ....|.|...||| | ..|. .| .|... ... . ....|||||. |||...|.|. . ....
gdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkveksk.eaksgpvvVhCsaGvgRtgtfvaldilleql
KTEGVIDVFQVLKSQRIQKPGSVQTVDR
..|. .||.|..|. | |.||.||...
eaeeevdvlqivkelRkqRpgmvqsleq
|
|||||||||
| 0045450 | (Phosphotyrosine protein) phosphatases II | 17-145 | 1.8e-25 | 85.8 | In-house | 158-291 (307) | alignment | ||
Range on Protein: 17-145
Range on HMM: 158-291/307.0
SGMILGEYNIILLNEETFNGYIERKFEVKNN-NTGATQSVTQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKR-GNTSIVVHCSDTVGRSAMFCAAATT
. . |.. . ||.||. .||. |..||... || . ||... |.| .| ......| |||. . ... ... ..||||. |||...|.|| .
eeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfeelldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylm
INKCKTEGV---IDVFQVLKSQRIQKPGSVQTVD
. ..||. .|.....| | |.||.||. .
lrqlekegtlldvdlleavkllreqRpgavqnpe
|
|||||||||
| subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 990-1083 | 2e-25 | 84.2 | In-house | 41-131 (287) | alignment | ||
Range on Protein: 990-1083
Range on HMM: 41-131/287.0
LNRFANIVVYDDNRITLRPMPGHkdcTNEYINACFIKDYSNQYQYIATQGPVSNTLVDFWQLIWQEKSTIIVMITNIIEEGKVKCQQYWPNSDT
||.|... .||.|. | . . .|||| .. | .. ..||.|||.. |. |||.......|. ....| .||.. || .|||. .
knryadvlPiddtrvllsaegel...GsdyinanyvasytddeafiaaqgPiaatvrdfwravletrsasvitmtreveearlkcykywPerev
|
|||||||||
| subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 1097-1305 | 2.2e-25 | 83.9 | In-house | 81-286 (290) | alignment | ||
Range on Protein: 1097-1305
Range on HMM: 81-286/290.0
PDYINAVFINGYKekKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSNRK-----LGEYNISLLNEEIHNAGYIERKIEVTnDN
||. | ...| | ||... .. .|. ..|.|. . .|.||||||. .. . | ||. ... .||. . .|. ..| | . . | |
GdyvhanyvkGlk..amfiltqGalkdtvidiwrmvlqekvaaivmlceliedGkakceqyypekeGevltfGeitvlcseeddkdaniikktlsvr.dk
KAGDKQQVKQYQITNWDSTGkLTNPQtiLLVIeEMYRTQRKRgNTSIVIHCSDTVGRSGVFCAAATTInKCKTEG-VIDVFQVLKSQRIQKPGSVQTVQQ
..| . ..| ..| | ... . | .. . |. || . .|.||| .||.| | | ... .. ..| .|. .. .. | . .||| |
dsGkehklkhlkikswpdks.valst..lall.rtlrilrka.sGpvvvhcsaGiGrtGtfvaievgl.qilldGkeldlldlvralrnsrlnsvqvdiq
YQGIFQIVLTYLDSF
| . .|.| . .|
ylalveilldlGkdf
|
|||||||||
| subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 1096-1299 | 2.7e-25 | 83.9 | In-house | 34-237 (239) | alignment | ||
Range on Protein: 1096-1299
Range on HMM: 34-237/239.0
HPDYINAVFINGYKE-KKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWS--NRKLGEYNISLLNEEIHnAGYIERKIEVTNDnK
| ||||| .. | ||.| .. . .. .||.|. . |||| . .. |.||| | . ..| . |. | || | . ...
hsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdstskycnlrvtlrktevf.adyiirtfvmsqv.g
AGDKQQVKQYQITNWDSTGKLTNpQTILLVIEEMYRTQRKRGNTSIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQ
... | ||..| | | | .| . . | ||||| |||.| | . . ..| . .|.|. .|. | ..| ||| .||
qteeryvyqyhftvwpdkgvpqy.atavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlrqakkqktvdifnyvkairedrphmvqtseqyv
GIFQIVL
|. ||
fihlavl
|
|||||||||
| subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 1096-1299 | 3e-25 | 83.8 | In-house | 35-238 (239) | alignment | ||
Range on Protein: 1096-1299
Range on HMM: 35-238/239.0
HPDYINAVFINGYKE-KKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWS--NRKLGEYNISLLNEEIHnAGYIERKIEVTNDnK
| ||||| .. | ||.| .. . .. .||.|. . |||| . .. |.||| | . ..| . |. | || | . ...
hsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdstskycnlrvtlrktevf.adyiirtfvmsqv.g
AGDKQQVKQYQITNWDSTGKLTNpQTILLVIEEMYRTQRKRGNTSIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQ
... | ||..| | | | .| . . | ||||| |||.| | . . ..| . .|.|. .|. | ..| ||| .||
qteeryvyqyhftvwpdkgvpqy.atavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlrqakkqktvdifnyvkairedrphmvqtseqyv
GIFQIVL
|. ||
fihlavl
|
|||||||||
| 0039614 | (Phosphotyrosine protein) phosphatases II | 18-145 | 4.1e-25 | 84.3 | In-house | 151-276 (297) | alignment | ||
Range on Protein: 18-145
Range on HMM: 151-276/297.0
GmILGEYNIILLNEETFNGYIERKFEVKNnnTGATQSVTQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKR-GNTSIVVHCSDTVGRSAMFCAAATTIN
| |.. . ||..|. .||. |..||.| .| . ||..| |.| | .....| ..|.. . ... ... ..||||. |||...|.|| . ..
g.tygdftvtllkvehldgytvrtlevtn..ngesrtvthfqytgwpdhgvppslellleflelvrealaelpkggpvlVHCsaGvgRtGtfiaaylmle
KCKTEGVIDVFQVLKSQRIQKPGSVQTVD
...|| .||....| | |.||.||| .
qlekeggvdvleavkelreqRpgavqtps
|
|||||||||
| DSPc_SM00195 | 21-145 | 4.7e-25 | 83.8 | In-house | 125-249 (263) | alignment | |||
Range on Protein: 21-145
Range on HMM: 125-249/263.0
LGEYNIILLNEETFN-GYIERKFEVKNNNTGATQSVTQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKRgNTSIVVHCSDTVGRSAMFCAAATTINKCK
|.... | ..|. . .| |..|...... |..|||||..|| | ... .| ...... .... .. ||||||. |||...|... . ..|..
fgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkksksts.sgpivVhCsaGvgRtgtfvtidiilskle
TEGVIDVFQVLKSQRIQKPGSVQTVD
.| .|.|...|. | |.||.||| .
eekkvdifeivkelRkqRpgmvqtle
|
|||||||||
| PTPc_SM00194 | 21-145 | 4.7e-25 | 83.8 | In-house | 125-249 (263) | alignment | |||
Range on Protein: 21-145
Range on HMM: 125-249/263.0
LGEYNIILLNEETFN-GYIERKFEVKNNNTGATQSVTQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKRgNTSIVVHCSDTVGRSAMFCAAATTINKCK
|.... | ..|. . .| |..|...... |..|||||..|| | ... .| ...... .... .. ||||||. |||...|... . ..|..
fgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkksksts.sgpivVhCsaGvgRtgtfvtidiilskle
TEGVIDVFQVLKSQRIQKPGSVQTVD
.| .|.|...|. | |.||.||| .
eekkvdifeivkelRkqRpgmvqtle
|
|||||||||
| 0042113 | (Phosphotyrosine protein) phosphatases II | 19-146 | 9.8e-25 | 82.8 | In-house | 104-231 (245) | alignment | ||
Range on Protein: 19-146
Range on HMM: 104-231/245.0
MILGEYNIILLNEETFNGYIERKFEVKNNNTGATQSVTQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKC
. |.. . ||.||....|. |..||.|. .. .. |..|. ..|. | ......| ..|.. . ... .|. ..||||. |||...|.|| . ..
ltygdftvtllseehlddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleql
KTEGVIDVFQVLKSQRIQKPGSVQTVDR
..|. .......| | |.||.||| .
ekelgvsleeavkelrsqRpgavqtpsq
|
|||||||||
| 0043336 | (Phosphotyrosine protein) phosphatases II | 19-146 | 1.1e-24 | 82.8 | In-house | 139-265 (278) | alignment | ||
Range on Protein: 19-146
Range on HMM: 139-265/278.0
MILGEYNIILLNEETFNGYIERKFEVKNNNTGATQSVTQYQITNWDSTGKLTNPQTILLVIEEMYRTQRkRGNTSIVVHCSDTVGRSAMFCAAATTINKC
. |.. . ||.||....|. |..||.|. .| .. ||.|. ..| | ......| .... . .. |. ..||||. |||...|.|. . ..
ltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldflkavreale.dsngpvlVHCsaGvgRTGtfialyllleql
KTEGVIDVFQVLKSQRIQKPGSVQTVDR
..|| .|.....| | |.||.||| .
ekeggvdleeavkelreqRpgavqtpsq
|
|||||||||
| subfamily_CG7180_pd | Subfamily CG7180 | 986-1093 | 1.6e-24 | 81.1 | In-house | 41-145 (296) | alignment | ||
Range on Protein: 986-1093
Range on HMM: 41-145/296.0
SNKLLNRFANIVVYDDNRITLRPMPGHKDCTneYINACFIKDYSNQYQYIATQGPVSNTLVDFWQLIWQEKSTIIVMITNIIEEGKvKCQQYWPNSDTKD
|. || ..| || ||. |. . |... |||| .. . . .|| |..|. .|. .||.|...|.. .|..|. . | ....|||| ..
enreknrdvkvvPyDynRvvLekldGeeksd..YinavyvdsflkkkeyivteapkketvdefWrlvydeeisavvvLtktfdfak.mypsywpnkskeq
YGPFSVTL
||.. | .
ygeifvei
|
|||||||||
| subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 985-1084 | 1.9e-24 | 81.0 | In-house | 31-128 (297) | alignment | ||
Range on Protein: 985-1084
Range on HMM: 31-128/297.0
PSNKLLNRFANIVVYDDNRITLRPMPGHKDctneYINACFI--KDYSNQYQYIATQGPVSNTLVDFWQLIWQEKSTIIVMITNIIEEGKVKCQQYWPNSD
.| ||. .|. .||.|. |. . .| |||| .. | ....|| .|||.|.|. |||.|.... .|||.... |.|. || |||...
nsslrknryrdilatddtrvkllrviterd....yinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrdkcapywpsvv
TK
.
qe
|
|||||||||
| 0049772 | (Phosphotyrosine protein) phosphatases II | 1098-1308 | 3.7e-24 | 81.4 | In-house | 73-286 (314) | alignment | ||
Range on Protein: 1098-1308
Range on HMM: 73-286/314.0
DYINAVFINGYkekKAFIIAESPMFNTARNF----------WKMI--DDRNVTAIVM---------------------LCQENKNNQEVCYQYWSNRKlg
||||| ...|. ..||... |. .| .| |.|. .|.|| ||| |.. |. | . ... . |
dyinasyvdgf...lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivmsrdevladelsrLdaAlgKtpllildgngneptaadlellk..
eynisllneeihnagyierkiEVTNDNKAGdKQQVKQYQITNWDStGKLTNPQTILLVIEEMYRTqrkRGNTSIVIHCSDTVGRSGVFCAAATTINKCkt
|...|.. .... .| .... | .. .. ..| . . . .. ...||.. .||.|.|..|| . ..
.....................eelydpelf.erlgikylripvpD.gsaplledfdeflefieea...dkggpvlvHCkaGkgRtgtfvvaaylmkll..
eGViDVFQVLKSQRIQKP-----GSVQTVQQYQGIFQIVLTYLDSFETY
|| .. ..|. | . | |.... .||. |....| ||. ....
.gv.sleealedvrlkRpinpnpgfieqleqyefilealleylkflkkf
|
|||||||||
| subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 1100-1290 | 5.5e-24 | 79.4 | In-house | 78-269 (301) | alignment | ||
Range on Protein: 1100-1290
Range on HMM: 78-269/301.0
INAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSNR-----KLGEYNISLLNE-EIHNAGYIERKIEVTNDNKA
| | .|. . . ||.. .|. ||. .|| |. .| ||||.|. ....|.| .| . . ..| ..| . |. | | ..|..||.. .
ihanwiptsGhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkisekldigrfkikiknkelilnkkiskrtlevedstgk
GDKQQVKQYQITNWDSTGkltNPQTILLVIEEMYRTqrKRGNTSIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQ
. . | || ..| | |.. . . | |. . ||.|||. .||| | .. .. ... |.. . || | .. .|||..|
fatrtvthyqysewtdrg...vPkshaelfdlmelv..kksekPivvhcsaGiGrsvafigteylareveadptieltealkhlrehrwngvqtnsq
|
|||||||||
| subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 21-154 | 7.7e-24 | 79.2 | In-house | 105-238 (250) | alignment | ||
Range on Protein: 21-154
Range on HMM: 105-238/250.0
LGEYNIILLNEETFNGYIERKFEVKNNNTGATQSVTQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKT
|. . ||..|.| |. ||. . ... . | |.. ..| | . ...| ..... ..|.. ||. ..|.|| |||| |.| . ... |.
yGdvtvsllskeefadytkrklklskakkaderivrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidavlerlkk
EGVIDVFQVLKSQRIQKPGSVQTVDRIIPDYFMI
| |.|||.|.| |...|..|.. .. . | .|
ekvvdvfkvikvlrkdrphavesleqyvfvyeii
|
|||||||||
| subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 1096-1300 | 8.7e-24 | 78.8 | In-house | 75-277 (439) | alignment | ||
Range on Protein: 1096-1300
Range on HMM: 75-277/439.0
HPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCqenknNQEVCYQYWSNRKLGEY-NIS-LLNEEIHNAGYIERKIEVTNDNKA
| |||| .|.|| ..| .| .. | .|. .||... ..... ||||. | |.|| . | .|. . .| |. | . | |.
hshyinanyikGyyddklyiatqgpkkettddfwrlviekktvtivmlt.....nlvesykywpsdaevcygdiavrvdrnielpnyvirgfkvfnerdt
GDKQ-QVKQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKRGNTSIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQ
..|. | |.. . | .. .| . . .. |. .|.||| |||.| | .... |.| .|. ..| | |. ||.. ||
tekertvlqfhyiawpdknvpaqashvldflrainsandkeeygpvvvhcsagvGrtGtiialdialeqlklenkvdikgivkvlrkqrkqmvqalcqyv
GIFQIVLT
|.. ||
fiynavle
|
|||||||||
| 0040439 | (Phosphotyrosine protein) phosphatases II | 19-145 | 1.8e-23 | 78.9 | In-house | 106-233 (249) | alignment | ||
Range on Protein: 19-145
Range on HMM: 106-233/249.0
MILGEYNIILLNEETFNGYIERKFEVKNNNTGATQSVTQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKR-GNTSIVVHCSDTVGRSAMFCAAATTINK
. |.. . ||..|....|. |..|..|. .| . |...|.|.| .| .....| ||.. ... .. ..||||. |||...|.|| . ..
leygdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylmleq
CKTEGVIDVFQVLKSQRIQKPGSVQTVD
..|. .|.....| | |.||.||. .
lekelgvdleeavkllrsqRpgavqnpe
|
|||||||||
| subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 946-1091 | 2e-23 | 77.5 | In-house | 5-145 (439) | alignment | ||
Range on Protein: 946-1091
Range on HMM: 5-145/439.0
DKFGEFVANGHAKGNEGFRNQFGMLDSGESDHTVTVGLTPS--NKLLNRFANIVVYDDNRITLRPMPGHKDctNEYINACFIKDYSNQYQYIATQGPVSN
|.| | | . . . .| |.. | ...| . |... |. .. ||. ... .| |.||. .|| |||| .|| | .. ||||||| .
defqehvekldknkqeifkeifekinstspdyaciaslaaqeydqtknrykdvgafdhtrvtlqeipgvph..shyinanyikGyyddklyiatqgpkke
TLVDFWQLIWQEKSTIIVMITNIIEEGKvkcqqYWPNSDTKDYGPFSV
| |||.|....|.. |||.||..| | ||| .. || .|
ttddfwrlviekktvtivmltnlvesyk.....ywpsdaevcygdiav
|
|||||||||
| subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 21-155 | 2.2e-23 | 77.9 | In-house | 146-281 (325) | alignment | ||
Range on Protein: 21-155
Range on HMM: 146-281/325.0
LGEYNIILLNEETFNGYIERKFEVKNNNTGATQSVTQYQITNWDSTGKLTNPQTILLVI---EEMYRTQR--KRGNTSIVVHCSDTVGRSAMFCAAATTI
.| .. | |.. |. |...||. . | |.|| |.|. || | | |.. .. ... . . .. | |.||||. |||. .| . . .
fGglevklrtieeisdyvhrvldvkqvkkGetrsvkqfqlqswddmGvqkrpatlisilqlvkavservtantkastpilvhcsaGvGrtGvfislysal
NKCKTEGVIDVFQVLKSQRIQKPGSVQTVDRiipdYFMIY
.| .| .|.|...| | ..| |.|||. | .||
akvieesrvdifgfvkklrkdrpsmvetvdq....yiliy
|
|||||||||
| subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 972-1085 | 3.5e-23 | 76.9 | In-house | 34-157 (350) | alignment | ||
Range on Protein: 972-1085
Range on HMM: 34-157/350.0
SGESDHTVTVGLTPSNKllNRFANIVVYDDNRITLR--PM----PGHKDCTNEYINACFIKDY------SNQYQYIATQGPVSNTLVDFWQLIWQEKSTI
| | .. |. | ||. ||. |. .|. |. . | ||.|||| ..| ...|||||.|. .|. ||...| . | ..
spsnDvilseGvelfak..nrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkv
IVMITNIIEEGKVKCQQYWPNSDTKD
|...|. .| . ||..||.. . .|
ilsltsdvelnlekcyrYWqegsydd
|
|||||||||
| subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 1095-1301 | 5.6e-23 | 76.0 | In-house | 64-268 (281) | alignment | ||
Range on Protein: 1095-1301
Range on HMM: 64-268/281.0
EHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSNRKLGEYNISLLNEEIHNAgYIERKIEVTND--NK
. ||| | .| |. .|... | .| .||.|| . | |||||||| . |.| | .|. .. | . .. ... . |
nstdyihanyirspflkrgyiltqgpkketradfwrmiwqenttaivmlcqfletnrekcaeyfprnahcclqfdklsvsyeds.tvnkslvttrlnlsy
AGDKQQVKQYQITNWDSTgKLTNPQTILLvieEMYRTQRKRgNTSIVIHCSDTVGRSGVFCAAATTINKCKTEG-VIDVFQVLKSQRIQ-KPGSVQTVQQ
|. . . .. .| .. . ..| .. | | | | ||||| ||||| . | ... .. . |. |.. |. . ||||.||
egetrlithwlwkewpdw.qvpessevml...kilrkirar.stppvihcsagvgrsgtlmaveialqsihshftlpdikqivshlrvtgraasvqtlqq
YQGIFQIVLTY
| |....| .
ymliwkvlldf
|
|||||||||
| PTPc_DSPc_SM00012 | 1198-1298 | 1.4e-22 | 75.3 | In-house | 1-103 (105) | alignment | |||
Range on Protein: 1198-1298
Range on HMM: 1-103/105.0
QVKQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKRG-NTSIVIHCSDTVGRSGVFCAAATTINKCKTE-GVIDVFQVLKSQRIQKPGSVQTVQQYQGIF
.||.|..|.| .|. .... || ..... . ..|.. ....|.|||. |||.|.|.|... ......| . .|.||..|. | |.||.||| .||. .
tvkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylfly
QIV
...
ral
|
|||||||||
| 0045098 | (Phosphotyrosine protein) phosphatases II | 19-145 | 1.8e-22 | 75.5 | In-house | 116-259 (278) | alignment | ||
Range on Protein: 19-145
Range on HMM: 116-259/278.0
MILGEYNIILLNEETFNGYIERKFEVKNN----NTGATQSVTQYQITNWDSTGKLTNP--QTILLVIEEMYRTQR------------KRGNTSIVVHCSD
.. |.. . ||.||... |. |...| | ... . ||......|. | ..| . .| ..|.. . .. ... ..||||
ltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvlVHCsa
TVGRSAMFCAAATTINKCktEGVIDVFQVLKSQRIQKPG-SVQTVD
|||.....|| . . . ||..|.....| | |.|| .||. .
GvgRtGtlvaaylmlell..eggvdlleavkelrsqRpglavqnle
|
|||||||||
| subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 1097-1309 | 1.9e-22 | 74.7 | In-house | 67-286 (307) | alignment | ||
Range on Protein: 1097-1309
Range on HMM: 67-286/307.0
PDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSNRKL-----G--EYNISLLNEEIHNAGYIERKIEVTN
||| | .. . | || |. |. || .|| |. . .| ...|||. . . | ||| . | ||. | ... | |.||.
sdyihanylgiaikpkkficaqgplentqysfwamaiqekvesvimlckvielakikceqywpleegqklvfgeapntisvanlgakklapdedlinvtt
DN--KAGDKQQVKQYQITNWDSTGkltNPQTILLVIEEMYRTQRKrgNTSIVIHCSDTVGRSGVFCAAATTINKC-KTEGVIDVFQVLKSQRIQKPGSVQ
. |.. . ....| .|| | ||. | |. . .. . . .|.||| ||||| | . .| . . |. .... | |.. ..|
lkvdwaqksrtiqhlqwenwpdrg...vpqinltainlleavryd..tnpvvvhcsaGvGrsGtivaislvqdkmiaGinckdmkklveelrsqrhyaiq
TVQQYQGIFQIVLTYL-DSF-ETYS
| || . ...| |. . . |||
teaqylylhrvlleyflelyketye
|
|||||||||
| subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 942-1083 | 2.1e-22 | 74.1 | In-house | 3-147 (392) | alignment | ||
Range on Protein: 942-1083
Range on HMM: 3-147/392.0
MIPVDKFGEFVANGHAkgNEGFRNQFGMLDSGESdHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMPGHKDctNEYINACFIKDYSNQYQYIATQGPV
||| .| || . . . | ..| | . . . ||. .. |. ||. ||. || .|. | . | ..|.|| .|. . |. |||.|||
pipvaqfpafveknrh..salffeefhdlpgpdi.ypqtvaqkeinlkknryknilpydsarvkleviddipd..sdylnasyipsfdnekayiasqgpn
SNTLVDFWQLIWQEKSTIIVMITNIIEEGK----VKCQQY----WPNSDT
. .| |||....||. | |.|.|.. | | . |. ||..|
aaslddfwrmvfqenvttiamvtklkegdkgddartvaqfhftewPdkdv
|
|||||||||
| 0051082 | (Phosphotyrosine protein) phosphatases II | 1096-1296 | 9.3e-22 | 72.7 | In-house | 2-147 (151) | alignment | ||
Range on Protein: 1096-1296
Range on HMM: 2-147/151.0
HPDYINAVFINGYkekkaFIIAESPmfntARNFWKMIDDRNVTAIVMLCQENKNNqeVCYQYWSNRKlgeynisllneeihnagyierkievtndnkagd
..||||. .. |. ... | |.... . ....||.|..| .. |..|. .
lsdyinfsyvtgg.....lyrsggp....ladflellkelgiktivnlrseeerg..ycpeylpelg.................................
kQQVKQYQITNWDSTGKLTNPQTILLVIEEMYRtqrkRGNTSIVIHCSDTVGRSGVFCAAATTINKcktegvIDVFQVLKSQRIQKPGSVQTVQQYQGIF
.|....|..|. .| ......| ..|.. . .| ...||| .||.|...|. . . ......|. |.. ||.||. ||.. ..
.ievlhipildwpdpglplsfdavleflellld....kkngpvlvHCsaGkgRTGtlvalylmllg......vsleealeeyrlkrpgvvqpnqqflfql
Q
.
f
|
|||||||||
| subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 948-1092 | 9.9e-22 | 71.9 | In-house | 14-155 (310) | alignment | ||
Range on Protein: 948-1092
Range on HMM: 14-155/310.0
FGEFVANGHAKGNEGFRNQFGMLDSgESDHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPmpgHKDCTNEYINACFIKDYSNQYQYIATQGPVSNTLVD
. .|. | ||. .|. ||. . | ..| . ||....|. |. |. |. | ..|| | ..| . .| .|||. |..|
lenfiiateklgieglvkqyrklda.kqdssltyeaykkymhknrysdvvcldtsrvklki...dksryedyihanyvktnylrstficsqgplqhtiid
FWQLIWQEKSTIIVMITNIIEEGKVKCQQYWPNS-DTKDYGPFSVT
||..|.||.. |... .. |||. || ||| |. || ||
fwrmifqeraesilllckvgeegrpkcvgywpslgvtetygcirvt
|
|||||||||
| subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 1093-1302 | 1.7e-21 | 71.5 | In-house | 62-271 (288) | alignment | ||
Range on Protein: 1093-1302
Range on HMM: 62-271/288.0
LREHPD-YINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSNRKLGEYNISLLNEEI-HNAGYIERKIEVT--
| . || ||.| . | |. .| |..|. | ..|||. . .| |||||. .| .|. .. . | | . .. |.. ..|.
lsddpdfyiaanvvssakykrrlicaqaPlngtieelWkmllesdveyivmlcellekGkeksaeyfPsklGekarigrlctvvkkkradidklvkvsll
NDNKAGDKQQ-VKQYQITNWDSTGKLTNPQTILLVIEEMyrtqrKRGNTSIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQT
. .| |.... ||. . .|| | | .. | ..| . | . ||.|.| |||.| . .. . . . . ..|.. | .. ..||
riskegeekvivkilhlleWdddgvPenylsplrllevl.....kslqkPivvhssaGvGrtgtlililialeslrlddflgirsllaklreerfkaiqt
VQQYQGIFQIVLTYL
.|| ....|| .|
emqylyvhrcvleel
|
|||||||||
| 0037934 | (Phosphotyrosine protein) phosphatases II | 17-145 | 2.8e-21 | 71.6 | In-house | 96-229 (243) | alignment | ||
Range on Protein: 17-145
Range on HMM: 96-229/243.0
SGMILGEYNIILLNEETFNGYIERKFEVKNNN-TGATQSVTQYQITNWDSTGKLTNPQTILLVIEEMYRTQRK-------RGNTSIVVHCSDTVGRSAMF
... |.. . ||.||....|. |.....| . .. |. |..|. ..| | ..|. .| ..|.. ... .. ..|||| |||....
gevtygdftvtllseehlddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtl
CAAATTINKCkteGvIDVFQVLKSQRIQKPG-SVQTVD
.|| . . .. | .|.....| | |.|| .||| .
iaaylmllll...g.vdleeavkllreqRpgkavqtps
|
|||||||||
| subfamily_PTPRA_pd | Subfamily PTPRA | 21-153 | 4.5e-21 | 70.1 | In-house | 155-290 (330) | alignment | ||
Range on Protein: 21-153
Range on HMM: 155-290/330.0
LGEYNIILLNEETFNGYIERKFEVKN----NNTGATQSVTQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKRGNtSIVVHCSDTVGRSAMFCAAATTIN
|. .. . .|. . | ||| |.. . ... |.|. | | | ..|. .| ..... ..... .. .|||||| |||. |.. . ..
yGnirvevedetvlvdytvrkflvqqlpdatrekksrlvrqfhftswPdvGvPfepiGmlkllkkvkklnqqsag.pivvhcsaGvGrtGtfivldavle
KCKTEGVIDVFQVLKSQRIQKPGSVQTVDRIIPDYFM
. |.|...|||...|. | |.| ||| . | .
rvkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykv
|
|||||||||
| subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 962-1081 | 6.4e-21 | 69.2 | In-house | 12-130 (281) | alignment | ||
Range on Protein: 962-1081
Range on HMM: 12-130/281.0
GFRNQFGMLDSGESDHTVTVGLTPSNKLLNRFANIVVYDDNRITLRP-MPgHKDCTnEYINACFIKDYSNQYQYIATQGPVSNTLVDFWQLIWQEKSTII
|...| | .|| | |. ||..|| . | |. |. || |. | .|| | .|. . || |||| .| |||..||||..| |
dfkqefsnlpgdppsdlctvfnqpvnnkknrylnipcldisrvqlkvkmp.nknst.dyihanyirspflkrgyiltqgpkketradfwrmiwqenttai
VMITNIIEEGKVKCQQYWPNS
||. ...| . || .|.|
vmlcqfletnrekcaeyfprn
|
|||||||||
| subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 956-1084 | 1.8e-20 | 68.1 | In-house | 11-134 (307) | alignment | ||
Range on Protein: 956-1084
Range on HMM: 11-134/307.0
HAKGNEGFRNQFGMLDSGEsDHTVTVGLTPSNKLLNRFANIVVYDDNRITLRpMPGhkdCTNEYINACFIKDYSNQYQYIATQGPVSNTLVDFWQLIWQE
|| . ....| .| . ..||| .| ||. .. . | .|| .. ..| . .|| | .. . ..|..||| || .|| .. ||
ldkgvqalvdefrvlakkt.pegvtveafsantdknryqdvkcqdkgrivvk.fdg...lasdyihanylgiaikpkkficaqgplentqysfwamaiqe
KSTIIVMITNIIEEGKVKCQQYWPNSDTK
| ..|. ..|| .|.||.|||| . .
kvesvimlckvielakikceqywpleegq
|
|||||||||
| subfamily_ptpA1_pd | Subfamily ptpA1 | 956-1081 | 3.2e-20 | 67.3 | In-house | 16-138 (418) | alignment | ||
Range on Protein: 956-1081
Range on HMM: 16-138/418.0
HAKGNEGFRNQFGMLDSGESDHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMPGhKDcTNEYINACFIkDYSNQYQYIATQGPVSNTLVDFWQLIWQE
| | ...| .|. . | | ||..||. . |. |. . |. ..|||| .| | . |.|.||||. ||. |||...|..
hikcihkikeefrlleesvgpsetsegdkkhntsknrytnilpvnhtrvqlkkiqd.ke.gsdyinanyi.dgaypkqfictqgplpntiadfwrmvwen
KSTIIVMITNIIEEGKVKCQQYWPNS
. ||||.. |. ..||..|||.
rcriivmlsresencrikcdrywpeq
|
|||||||||
| subfamily_PTPRK_pd | Subfamily PTPRK | 19-146 | 8.3e-20 | 65.8 | In-house | 137-265 (314) | alignment | ||
Range on Protein: 19-146
Range on HMM: 137-265/314.0
MILGEYNIILLNEETFNGYIERKFEVKN--NNTGATQSVTQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKrGNTSIVVHCSDTVGRSAMFCAAATTIN
.. |. .. |.. |. . .. | | |.. . ... | |.| ..| . . .. ...| .. .. .| . .. |||||| ||. .|.| .. ..
evygdikvelvetellaelvvrifrveklargqeeirevrqfqflgWpdhdvPvsatgllklvrrvkksqee.eaGrivvhCsaGaGrtGtfiaidivld
KCKTEGVIDVFQVLKSQRIQKPGSVQTVDR
..|||.|||.. |. | .|. |.| ..
mieregvvdvfnavktlrsrkvnmveteeq
|
|||||||||
| PTPc_DSPc_SM00012 | 55-147 | 9.6e-20 | 66.1 | In-house | 2-96 (105) | alignment | |||
Range on Protein: 55-147
Range on HMM: 2-96/105.0
VTQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKRG-NTSIVVHCSDTVGRSAMFCAAATTINKCKTE-GVIDVFQVLKSQRIQKPGSVQTVDRI
|..|..|.| .|. .... || ..... . ..|.. ....|||||. |||...|.|... ......| . .|.||..|. | |.||.||| .
vkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqy
|
|||||||||
| subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 21-146 | 1.5e-19 | 65.3 | In-house | 145-272 (297) | alignment | ||
Range on Protein: 21-146
Range on HMM: 145-272/297.0
LGEYNIILLNEETFNGYIERKFEVKNNNTGATQSVTQYQITNWDSTGKLT--NPQTILLVIEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKC
.|. ..|| . .|.|.|..||..... |.. | ||| ..| . . ...| .|.|. . .. .. ..|||. ||| ..... . .
fGdvsvvllsvsereGfikrelevtkgkakarrvvkqyqfveWPdkaverkdsassllklisevrkdfsqnaegPllvhclaGvGrtgvlltidsvvaea
KTEGVIDVFQVLKSQRIQKPGSVQTVDR
| | .|.|...| | ..| ||| .
krekevdifglvkklrqerpylvqtkeq
|
|||||||||
| subfamily_CG42327_pd | Subfamily CG42327 | 985-1095 | 2e-19 | 64.4 | In-house | 26-139 (319) | alignment | ||
Range on Protein: 985-1095
Range on HMM: 26-139/319.0
PSNKLLNRFANIVVYDDNRITLRPMPgHKDcTNEYINACFIKDYSN-QYQYIATQGPVSNTLVDFWQLIWQEKSTIIVMITNIIEEGKVKCQQYWPNSDT
.. | .|..|.| . |..|. .. .| .||..| ... | . . .|||.| . .. |||...|. .| .|| .|.. | | .| .|.| ..|
vtskdksrvinvvPlPetrvvlqrig.ddd.kdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlselGikvcaeylPtket
KD----YGPFSVTLRE
| || . |||..
ldntslyGdilvtlkg
|
|||||||||
| subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 21-146 | 3e-19 | 64.0 | In-house | 143-265 (315) | alignment | ||
Range on Protein: 21-146
Range on HMM: 143-265/315.0
LGEYNIILLNEETFNGYIERKFEVKNNNtgATQSVTQYQITNWDSTGKLTNPQTILLVIEEMYRTqRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKT
.|.... ||. |. . . ||. ... . ... |||.| |.| | . ..| .| |. ... . |..|||| |||. ..... ... |
fGsikvellsleadtdgvarklvtrkse..esrtvtqfqftewPdkGvdkqtssllklikevkad.ngkkefsllvhcsaGvGrtGvvisidevvaqikr
EGVIDVFQVLKSQRIQKPGSVQTVDR
. ..|||...| | ..| ||| ..
trsvdvfnfvknlrakrpylvqteee
|
|||||||||
| subfamily_Ptp69D_pd | Subfamily Ptp69D | 25-154 | 3.5e-19 | 64.1 | In-house | 149-282 (307) | alignment | ||
Range on Protein: 25-154
Range on HMM: 149-282/307.0
NIILLNEETFNGYIERKFEVKNNN-----TGATQSVTQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKRgNTSIVVHCSDTVGRSAMFCAAATTINKCK
.. | .||. . ||.|...| ... ... |.||. |.|. . ....| .||... ... .. |||||| ||||..| | . ....|
lvklvseekhsdyiiReldvskkkeesgevedsrkvvqyhytgWkDskvPevargllklieqvrelykln.rsPivvhCsaGvgrsgifvaldsllqqlk
TEGVIDVFQVLKSQRIQKPGSVQTVDRIIPDYFMI
.| .|.|.. | | |.. || . . | .
aedkvdifetvkdLrsqRnllvqsleqYvflyral
|
|||||||||
| 0044763 | (Phosphotyrosine protein) phosphatases II | 1092-1298 | 4.5e-19 | 64.2 | In-house | 13-167 (178) | alignment | ||
Range on Protein: 1092-1298
Range on HMM: 13-167/178.0
TLREHPDYINAVFINGYkekkaFIIAESPMfntaRNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSNRKLgeynisllneeihnagyierkievtndn
| |||||..| .. .... |. ...... . ..|.||.|..| .... |..|| .
eglersdyinaseilpg.....lylgslpp....addlellkelgithivnlteelelgflkcdpywpeeag............................
kagdkqqvKQYQITNWDSTGKLTNPQTILLVIEEMYRTQRkRGNTSIVIHCSDTVGRSGVFCAAATTINKckteGViDVFQVLKSQRIQKPgSVQTVQQY
||. .... | . .. .| ..| . . . . . ...||| |||||...|| . |. ....... | ..| |.. |.
........iqylhipipDhgvpdllehflefvefieeald.ekggpvlVHCsaGvgRsgtlvaaylmkkl....gl.sleeaielvrerRp.ivpnpgql
QGIFQIV
. . ..
rqLyefe
|
|||||||||
| subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 21-147 | 5.7e-19 | 63.2 | In-house | 145-268 (288) | alignment | ||
Range on Protein: 21-147
Range on HMM: 145-268/288.0
LGEYNIILLNEETFNGYIERKFEVKnnNTGATQSVTQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKRgNTSIVVHCSDTVGRSAMFCAAATTINKCKT
|. ...|..... . ...||.... .. .|||| . | .| . . .| ... . .. . |.||||. |||. | |. . |.. ..
yGsvtvtlveskeledfvlrkllle..kkkteleitqyqylaWpdhgvPeskapllellrqvkvanqad.tgpiivhCsaGvGrtgtFialdalidavee
EGVIDVFQVLKSQRIQKPGSVQTVDRI
| .|||. ... | |.. |||. .
edyiDvagtvaklRkqRallvqtlkqY
|
|||||||||
| subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 950-1084 | 7.6e-19 | 62.6 | In-house | 11-139 (305) | alignment | ||
Range on Protein: 950-1084
Range on HMM: 11-139/305.0
EFVANGHAKGNEGFRNQFGMLDSGESDHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMPGHkdctnEYINACFIKDYSNQYQYIATQGPVSNTLVDFW
.|| . || .|.|..| . . . . .. ||. .. |.||. |.. | ||| | .. .| ..| || |. .| |||
kfvkrtlekgpaglraefvamkrfndfekmkafkeaqeagknrykdvgcldnnrvklegpwph.....eyihanyvstptnpkrfictqaplektcadfw
QLIWQEKSTIIVMITNIIEEGKVKCQQYWPNSDtK
. .|.| | |. |..| | ||..|.. | |
ymclqdkveaifmlcnllekgakkcleyfaskd.k
|
|||||||||
| subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 1097-1302 | 9.4e-19 | 62.2 | In-house | 80-289 (305) | alignment | ||
Range on Protein: 1097-1302
Range on HMM: 80-289/305.0
PDYINAVFING-YKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSNRKLGE--YNISLLNEEIHNAGYIERKIE--VTNDN
||| | .. .| || |. |. .| .|| |. ...| |||||. . . | ||| . . .. |.. . .|| | .| |
sdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkveqivmlcktvelgklkcaqywpaaqgeklelksgivvenvsgskpmerdaeiqitlln
--K-AGDKQQVKQYQITNWDSTGKltnPQTILLVIEEMyRTQRkRGNTSIVIHCSDTVGRSGVFCAAATTINKCKTE-GVIDVFQVLKSQRIQKPGSVQT
..| |.. | |.| | | | .| . . | . ||.||| .||.| | ..| . . . ...|. | |. |.|.
ltysgdqkmsvrhlqwtewpdrgv...ppckltslell.sair.gskvpivvhcsagigrtgtivaieyilekiaenkpcppmpelvkalrdqrafsiqn
VQQYQGIFQIVLTYL
|| | ...| |.
dvqylfihrvmlnyf
|
|||||||||
| subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 21-146 | 9.7e-19 | 61.8 | In-house | 142-264 (515) | alignment | ||
Range on Protein: 21-146
Range on HMM: 142-264/515.0
LGEYNIILLNEETFNGYIERKFEVKNNNTgaTQSVTQYQITNWDSTGKLTNPQTILLVIEEMyRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKT
.|.... |. |. | | ||..| .. .. |||.. |.| | . ...| .| |. .... . . ....||| ||| ..... . . ||
fGsikvelvsleactggikrkltvlkgdd..srtvtqfhfteWPdkGvpkhtssllklikev.kadhgqythpliihcsaGvGrtGvvisidsvvahakt
EGVIDVFQVLKSQRIQKPGSVQTVDR
..|||.... | ..| ||| ..
trmvdvfnfvtnirqkrpylvqtqeq
|
|||||||||
| subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 19-145 | 1.7e-18 | 61.7 | In-house | 137-263 (281) | alignment | ||
Range on Protein: 19-145
Range on HMM: 137-263/281.0
MILGEYNIILLNEETFNGYIERKFEVkNNNTGATQSVTQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKC
...|.. . ..||. . ||||||.. ....| |..|.| . |.| .| .... .| .|......|. ....|.||| |||. . | . ....
lkygdvtvkstaeeekatyierkfkl.eresgetreveqlaytaWPdhGvPattkellefrkevlkltekktkaplvihCsaGvGrtGtyialDrlvkav
KTE-GVIDVFQVLKSQRIQKPGSVQTVD
..| .|| .|... | .. ||||
eaeleeldvkavvaelrkernlmvqtvv
|
|||||||||
| subfamily_PTPN23_pd | Subfamily PTPN23 | 20-151 | 2.5e-18 | 60.9 | In-house | 138-273 (288) | alignment | ||
Range on Protein: 20-151
Range on HMM: 138-273/288.0
ILGEYNIILLNEETFNGYIERKFEVKNNNTGATQSVTQYQITNWDSTGKLTNPQTILLVI---EEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTIN
|.... | .... . ..||..... ... |..||. |.|.| . | |.|.| .. |..|...... .| .||||| |||. .|. . ..
kfgdlsvtlksvretethvervlkletldadavksvshlqltsWpelGvPasPetllqfldevesayeavqrksktPlvvhCsaGvgRtgvfalvyaavr
KCK-TEGVIDVFQVLKSQRIQKPGSVQTVDRIIPDY
. . .|..|. ||.. | |. .||..... |
elekgnglldiiqvvsrlreqRrfmvqekeqlkfsy
|
|||||||||
| subfamily_PTPRB_pd | Subfamily PTPRB | 19-147 | 7.1e-18 | 59.6 | In-house | 147-274 (293) | alignment | ||
Range on Protein: 19-147
Range on HMM: 147-274/293.0
MILGEYNIILLNEETFNGYIERKFEVKNnnTGATQSVTQYQITNWDSTGKLTNPQTILLVIEEMYRTQ-RKRGNTSIVVHCSDTVGRSAMFCAAATTINK
.. |. .. |..||. . .. |...... . ....|.||. | | | ...|.| .... ... .. .. |||||| |||. | | . ...
vlyGdikvtlvaeeeledwvirelkiek..ekeerkvrqyhftsWpdhgvPektktlldfvrtvreaiektaskrPivvhCsaGvGRtGtfialdrllqa
CKTEGVIDVFQVLKSQRIQKPGSVQTVDRI
..| ..|.| .. . | .. |||...
ieeedyvdifgivaelReeRnllvqtekqY
|
|||||||||
| subfamily_PTPN12_pd | Subfamily PTPN12 | 20-146 | 8.6e-18 | 59.2 | In-house | 138-265 (290) | alignment | ||
Range on Protein: 20-146
Range on HMM: 138-265/290.0
ILGEYNIILLNEETFN-GYIERKFEVKNNntGATQSVTQYQITNWDSTGKLTNPQTILLVIEEMYRTQRkRGNTSIVVHCSDTVGRSAMFCAAATTINKC
||... | .|.... ... | ..|... .....|.|.. |.| | ......| .||.. ..|. . .. .||||| ||| .| . .
efgefevtleeekavdddflirtLkveaq..kesrkvyqfhYtaWPDhgvPssaksllelielvrelqe.sedaPlvvhCsaGvGrtGtiiaidyvrell
KTEGV---IDVFQVLKSQRIQKPGSVQTVDR
|.| . .|||... . | |.. ||| ..
kaekipeeldvfdlvlelrkqraalvqtkeq
|
|||||||||
| subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 991-1084 | 1.5e-17 | 58.1 | In-house | 60-146 (290) | alignment | ||
Range on Protein: 991-1084
Range on HMM: 60-146/290.0
NRFANIVVYDDNRITLRpmpghKDCTNEYINACFIKDYSNqyQYIATQGPVSNTLVDFWQLIWQEKSTIIVMITNIIEEGKVKCQQYWPNSDTK
||. ..| | |. |. .|. | ..| .| |||.. .| .|.|... ||| . |||. ..||.|| ||.||.|. . .
nrykdvvcndktrvilk.....dGydGdyvhanyvkGlka..mfiltqGalkdtvidiwrmvlqekvaaivmlceliedGkakceqyypekeGe
|
|||||||||
| subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 977-1087 | 2.1e-17 | 58.0 | In-house | 23-126 (267) | alignment | ||
Range on Protein: 977-1087
Range on HMM: 23-126/267.0
HTVTVGLTPSNKLLNRFANIVVYDDNRITLRpmpghkDCTNEYINACFIKDYSNQYQYIATQGPVSNTLVDFWQLIWQEKSTIIVMITNIIEEgkvKCQQ
|.. .. |. ||. . . |||.|. || . ..||||| ... | . ..|.||.|..|| ||...| ..| ..||..|.. .. . ..
stisqsiaeknqernrlddnlpyddtrvilr......tkeeeyinasyvegyktknafivtqdplkntitdfltvihdqkvpvivlltkvftd...nirl
YWPNS--DTKDYG
.|| ..| |
fwPPkmgqakkyq
|
|||||||||
| subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 35-148 | 2.3e-17 | 57.9 | In-house | 139-249 (267) | alignment | ||
Range on Protein: 35-148
Range on HMM: 139-249/267.0
NGYIERKFEVKNNNTGAtQSVTQYQITNWDSTGKltNPQTILLVIEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQR
| | .|.| .| | . || | .|. . | . .. . . | . || .||.||| |||| | . . ... ||||| |.|. |. |
ndyqiitlelkfknesa.hnvtlyyykkwnintn..nkpylkplfgilaknqlengnrPlvvacsdGvGrsGtflvidsqleraktegvsdifdflrkir
IQKPGSVQTVDRII
|..| |.| .| |
sqriglvdtkeryi
|
|||||||||
| subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 31-156 | 4.8e-17 | 57.2 | In-house | 163-285 (319) | alignment | ||
Range on Protein: 31-156
Range on HMM: 163-285/319.0
EETFNgYIERKFEVKN-NNTGATQSVTQYQITNWDSTGKLTNPQTILLVIEE-MYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQ
||| . |. |..|. . . ...||. . | |. | .. ... . |........|||||| |||. .. . . ... | | .||..
eetae.yvvrdielsedgkekdirkitqfhflGwpdvGvpdypsdlmrlvkkvrhltskenhranivvhcsaGvGrtGvyivldvlldrmkeekqvdvyn
VLKSQRIQKPGSVQTVDriipDYFMIYA
... | |.. || . .|..||.
fvrdlrqqrntlvqdlv....qykfiys
|
|||||||||
| subfamily_PTPN6_pd | Subfamily PTPN6 | 21-155 | 5.3e-17 | 56.8 | In-house | 153-290 (306) | alignment | ||
Range on Protein: 21-155
Range on HMM: 153-290/306.0
LGEYNIILLNEETFNGYIERKFEVK-NNNTGATQSVTQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKRG---NTSIVVHCSDTVGRSAMFCAAATTIN
|.... ..|.. . || |.. |. ... . ...| ||. ..| | ..|...| .|.. | |.. . .||||||. .|| | . ..
yGkisvtnvseksladYilRelsvskkkkkkeerevfqyhfksWPdhgvpkdpgavLdfledvnrkqeeleeaeagpivvhCsaGiGRtGtfiviDillk
KCKTEGV---IDVFQVLKSQRIQKPGSVQTVDRiipdYFMIY
. ...|. ||. .. || | |. | ||| . | ..|
liekkgldadidiqklvksvreqrsglvqteqq....ykfvy
|
|||||||||
| subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 31-156 | 5.6e-17 | 57.1 | In-house | 127-249 (284) | alignment | ||
Range on Protein: 31-156
Range on HMM: 127-249/284.0
EETFNgYIERKFEVKN-NNTGATQSVTQYQITNWDSTGKLTNPQTILLVIEE-MYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQ
||. . |. |..|. . . ....|. . | |. | .. ... . |........|||||| |||. .. . . ... | | .||..
eesee.yvvrdielsedgkekdirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrtgvyivldvlldrmkeekqvdvyn
VLKSQRIQKPGSVQTVDriipDYFMIYA
... | |.. || . .|..||.
fvrdlrqqrntlvqdlv....qykfiys
|
|||||||||
| subfamily_ptpA1_pd | Subfamily ptpA1 | 1094-1261 | 8.8e-17 | 55.9 | In-house | 72-255 (418) | alignment | ||
Range on Protein: 1094-1261
Range on HMM: 72-255/418.0
REHPDYINAVFINGYKEkKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSNRKLGEY-NISLLNEEIHNAgYIERKIEVTNDNK
.| ||||| .|.| | || .. |. || .||.|. . . |||| .|..| . | .|| .. || .| .|. . | .|| .| .
kegsdyinanyidgayp.kqfictqgplpntiadfwrmvwenrcriivmlsresencrikcdrywpeqiggeqfsiygngnevfgt.ysvelveviqdpe
------------AGDKQQVKQYQITNWDSTG--KLTNPQTILLviEEMYRTQ-----RKRGNTSIVIHCSDTVGRSGVFCAAATTINK
|. ... ||| | |.| || . | | |..||| |||.| ||.| ..|
reiitrnirltfegetrditqyqyegwpdhnipdhtqpfrqll..hsitnrqnqiipssdrnvpiivhcsagvgrtgtfctavimmkk
|
|||||||||
| subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 1109-1297 | 1.2e-16 | 55.5 | In-house | 2-199 (199) | alignment | ||
Range on Protein: 1109-1297
Range on HMM: 2-199/199.0
KEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSNRKL--GEYN-ISLLNEEIH-NAGYIERKIEVTNDNKAG-DKQQVKQYQ
| .. .| .. |. .| .||.|. . |||. ...||.. ||. . |.| .|. . | .. | . .||. | ... .||
kgqrryiatqhplretmadfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyq
ITNWDST--GKLTNPQTILLVIEEMYRTQRKRGNTSIVIHCSDTVGRSGVFCAAATTIN---KCKTeGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQI
.| | ... ... |. . . .. ...|||| | .||| | . . || |.|.|.| | | . | . ..|.|. |.|.
ftswkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheeskt.svvdlfevakrlrqarcgiisslqhynfiyqv
|
|||||||||
| subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 1110-1297 | 1.5e-16 | 55.1 | In-house | 2-198 (198) | alignment | ||
Range on Protein: 1110-1297
Range on HMM: 2-198/198.0
EKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSNRKL--GEYN-ISLLNEEIH-NAGYIERKIEVTNDNKAG-DKQQVKQYQI
.. .| .. |. .| .||.|. . |||. ...||.. ||. . |.| .|. . | .. | . .||. | ... .||.
gqrryiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqf
TNWDST--GKLTNPQTILLVIEEMYRTQRKRGNTSIVIHCSDTVGRSGVFCAAATTIN---KCKTeGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQI
| | ... ... |. . . .. ...|||| | .||| | . . || |.|.|.| | | . | . ..|.|. |.|.
tswkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheeskt.svvdlfevakrlrqarcgiisslqhynfiyqv
|
|||||||||
| subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 30-146 | 1.6e-16 | 55.2 | In-house | 140-256 (274) | alignment | ||
Range on Protein: 30-146
Range on HMM: 140-256/274.0
NEETFNGYIERKFEVKNNNTgaTQSVTQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKRGNT--SIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVF
. . |.| ||. .|. . ..||. | |.| . ...|.| ...|. ...... . ..||||| .|| .| |. .... . |.|.||.
kiverndysvrklvlkyler..ersvkhywytdWPdhksPddantlldlvleveesreeenaklapvvvhCsaGiGrtGcfiaisiavrqlreeivvdvl
QVLKSQRIQKPGSVQTVDR
.. |... | ||| ..
kivcnlrldrGGmvqtseq
|
|||||||||
| subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 1098-1303 | 1.8e-16 | 54.7 | In-house | 74-288 (305) | alignment | ||
Range on Protein: 1098-1303
Range on HMM: 74-288/305.0
DYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSNRKLGEY-------NISLLNEEIHNAGYIE------RK
.|| | .. . | || ...|. .| .|| | . .| || |||. . . |..|.. .. . ||. | .. . . ..
eyihanyvstptnpkrfictqaplektcadfwymclqdkveaifmlcnllekgakkcleyfaskdkdvlefeekgqkisvkfessvtlkfrkdakakvte
IEVTNDNKAGDKQQVKQYQITNWDSTGKLTNPQTillVIEEMYRTQRKRGntSIVIHCSDTVGRSGVFCAAATTINKCKTEGVID-VFQVLKSQRIQKPG
... . .....|..| .| | . .. ..| . ... .| ||.||| .||.| ... . .|. ..|. | |.
tvlviegpgekarkvthyhwidwpdrgvpaadla...ilellekarpskg..pivvhcsagigrtgsvvmleyildqllagqiiedtdkilqkireqrnn
SVQTVQQYQGIFQIVLTYLD
|.|| .|| . |..| |.
siqtdaqylfvhqvilnyfr
|
|||||||||
| subfamily_PTPRG_pd | Subfamily PTPRG | 21-145 | 2.3e-16 | 54.1 | In-house | 145-274 (563) | alignment | ||
Range on Protein: 21-145
Range on HMM: 145-274/563.0
LGEYNIILLNEETFNGYIERKFEVKNNNTGAT------QSVTQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKrGNTSIVVHCSDTVGRSAMFCAAATT
.|. .. | .||.. | .|.. .|| . .. . |.||. |.| .| . . | .. ..... |||||| |||. .... |
ygalqvtlieeevlalytvrtlviknlklkkkkqcdteklvrqyhytkWPdhgvPehslpvLifvkkssaanka.eaGPivvHcsaGvgrtGtyivldtl
INKCKTEGVIDVFQVLKSQRIQKPGSVQTVD
... ..| ...||..|| | |.. ||| .
lkqiqqenavnvfgflkhiraqRnflvqteE
|
|||||||||
| subfamily_PTPN13_pd | Subfamily PTPN13 | 20-151 | 2.4e-16 | 54.9 | In-house | 133-262 (273) | alignment | ||
Range on Protein: 20-151
Range on HMM: 133-262/273.0
ILGEYNIILLNEETFNGYIERKFEVKNNNTGATQSVTQYQITNWDSTGKLTNPQTILLVIEEMYRTQRkrGNTSIVVHCSDTVGRSAMFCAAATTINKCK
. . ... ||. . .|. |...||....|... |.. . ..| | .... .| .. |. | |. .. |||||| .||| .. . . .. .
vsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaellqfvaevrrlqt..dagPivvhcsaGiGrsGtlitidvvlglie
TEGVIDVFQVLKSQRIQKPGSVQTVDRIIPDY
. .|| ..... | |. | ||| |. | |
rdkefdvkeivrklreqrqgvvqtkdqyifvy
|
|||||||||
| subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 1117-1295 | 2.6e-16 | 53.9 | In-house | 96-281 (302) | alignment | ||
Range on Protein: 1117-1295
Range on HMM: 96-281/302.0
AESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSNR-----KLGEYNISLLNEEIHNAGYIE------RKIEVTNDNKAG-DKQQVKQYQI
| .| .| .|.. ||. .| ||. ..... | .|.|.. |.|.| . .. . . . . . ..|..|..| |. |. .
pivpkkstlekhwalieqynvaivvqlcsfvedeekkcaeyysdkvggelkfgrytvktvsvktdleeftdkksfklytveiknekkkkkvkktvdilaf
TNWDSTGKLTNPQTILLVIEemYRTQRKrgnTSIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIF
. | | ...| | .. . | .....||| |||.| . | |. |... | |. .... | . |.||. || ..
sawpdhGapkeaytaldilk..fcesyk...knvlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqdeqqliyll
|
|||||||||
| subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 986-1095 | 3.3e-16 | 54.1 | In-house | 34-140 (285) | alignment | ||
Range on Protein: 986-1095
Range on HMM: 34-140/285.0
SNKLLNRFANIVVYDDNRITLrpmpghKDCTNEYINACFIKDY-SNQYQYIATQGPVSNTLVDFWQLIWQEKSTIIVMITNIIEEGKVKCQQYWPNS--D
.| |||.|.. . .. |. | |. .|| | ... .| ||.||||. .|| |||..|.||| . ..|. ..| | || |.|. .
anpdlnryadvrcieetrvvl......knhdrdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyypeklge
TKDYGPFSVTLRE
.| . .|| |
vvkfgkyeitlte
|
|||||||||
| subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 1091-1302 | 6.2e-16 | 53.2 | In-house | 52-270 (285) | alignment | ||
Range on Protein: 1091-1302
Range on HMM: 52-270/285.0
VTLREH-PDYINAVFIN-GYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSNR-----KLGEYNISLLN-EEIHNAGYIE
| |..| ||| | .. |.. ..| .. |. .| .||.|| . ... ..||| . | | |. .. |.|.|.|.| . .| || |
vvlknhdrdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyypeklgevvkfgkyeitlteckeeaiagtil
RKIEVTNDNKAGDKQ-QVKQYQITNWDStgKLtNPQTILLVIeEMYRTQRK--RGNTSIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRI
. |.| . | . ... |. | .| |. .| |.|. .| .. |..||| |||. | . . . |....... |
naltvintedasseplymnhvqvpwwpd..ql.apedarpmi.elykwvkkvnpkekpicvhcsagvgrtatfvgidyatirimenpniemldivremra
QKPGSVQTVQQYQGIFQIVLTYL
. .||. |. .. ... |.
mrfqavqshmqflflyvvlmeyf
|
|||||||||
| subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 19-146 | 6.7e-16 | 53.1 | In-house | 143-267 (315) | alignment | ||
Range on Protein: 19-146
Range on HMM: 143-267/315.0
MILGEYNIILLNEETFNGYIERKFEVKNNNtgATQSVTQYQITNWDsTGKLTNPQTILLVIEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKC
.| |.. . . .|| .. | | . | .. . | |...| | . .... . |. . . .. ..||||||. |||. |.. . ...
viyGkitvtrkseevnteytvrtlsvvfgd..nirevvqlhytswp.dmgvpkytiplmnlirtvkqhhtnsvgaivvhcsaGvGrtGtfitldavldqa
KTEGVIDVFQVLKSQRIQKPGSVQTVDR
..| .|||..... | .. . ||....
eaenaidvynfitgvrqnrikmvqvaeq
|
|||||||||
| 0041856 | (Phosphotyrosine protein) phosphatases II | 987-1083 | 8.8e-16 | 53.5 | In-house | 1-76 (182) | alignment | ||
Range on Protein: 987-1083
Range on HMM: 1-76/182.0
NKLLNRFANIVVYDDNRitlrpmpghkdcTNEYINACFIKDYSNQYQYIATQGPVSNTLVDFWQLIWQEKSTIIVMITniieegkvkCQQYWPNSDT
|. .||. .|. || .| . |||| .. . . ..|||||| .|. ||........ |.||..| . .|||. .
nldknrysdilpydhsr............dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt.........eelywpelle
|
|||||||||
| subfamily_PTPN3_pd | Subfamily PTPN3 | 20-145 | 8.9e-16 | 52.6 | In-house | 138-262 (280) | alignment | ||
Range on Protein: 20-145
Range on HMM: 138-262/280.0
ILGEYNIILLNEETFNGYIERKFEVKNNNTGATQSVTQYQITNWDSTGKLTNPQTILLVIEEMyRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCK
.||... . .|.. . |. |.. .|...| ....| | ..| | .... .| ..|.. |..|. .. .||||| .||. .. . |.. .
eygefsvkcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefverv.rklrsgkeePvvvhCsaGigrtGvlilletalalie
TEGVIDVFQVLKSQRIQKPGSVQTVD
.. . . .... | |. |||..
aaepvypldivrtmrdqramlvqtas
|
|||||||||
| subfamily_egg_pd | Subfamily egg | 1098-1302 | 1.2e-15 | 52.0 | In-house | 69-270 (307) | alignment | ||
Range on Protein: 1098-1302
Range on HMM: 69-270/307.0
DYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNnqEVCYQYWSNRKLGEYNI---SLLNEEIHNAGYIERKIEVTNDNKAG
|.| | ..| ||.|..|. || .||.|. .| |||| .. | | || . . . || | .. . ||. . |
dfihanrvkGkpllnefilaqaplkntvddfwrmvfqeevqyivmltsrkes..erceyywpkaesdslvtvpGslrienlkvdskadplfrvtklklvG
DKQ---QVKQYQiTNWDSTGKLTNPQTILlvieemyRTQRKRgNTSIVIHCSDTVGRSGVFCAAATTINKCKtEGVIDVFQVLKS---QRIQKPGSVQTV
.. .. .| ... .... | .| | |. . .|... . | ..... |. ... . | | . ||.. | ... ||..|
gddeerflehwq.gdvnnssdvysplrvl.......rklrnl.skpvvvqdilGvskaatlvaieiallsll.rGpitkslvlravvflrlrrrlsvesv
QQYQGIFQIVLTYL
.| ....|| ..
llylfvyrlvlfff
|
|||||||||
| subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 1078-1308 | 1.6e-15 | 51.6 | In-house | 49-282 (312) | alignment | ||
Range on Protein: 1078-1308
Range on HMM: 49-282/312.0
WPNSDTKDYGPFSVTLREHpDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSNR----KLGEYNIS-LLN
.|| . | | |... | || | |.. . |.....|. ||. .||.. |.|..|| .. | | .| |. .| .. .
ypniqcwdrgrftlagden.fyihanfvkictkperfvctqgplentcthfwqlalslgstsiillcgfvedgsekcakyisdivgfvdledhrvyteyc
EEIHNAGYIERKIEV----TNDNKAGDKQQVKQYQITNWDSTGKLTNPQTILLVIEEMyrtqrKRGNTSIVIHCSDTVGRSGVFCAAATTI---NKCKTE
|| | || . .|.. ....|| . | | .| | .. . |. . .. ||| |||.| .. . | . . .
teieiggkskdkithrvlkvvvkatgqesklnhyqwaswpdhgmpdscdtalrllsav.....kkdkkpviahcsagvgrtgtlaliesmiaalrhprkq
GVIDVFQVLKSQRIQkpgSVQTVQQYQGIFQIVLTYLDSFETY
| |.| .|. .| . ||... || ...|| .| | |
nvkdsfvllrkdrar...svrvfpqyvyalrcvleflyskgly
|
|||||||||
| 0049772 | (Phosphotyrosine protein) phosphatases II | 975-1076 | 2.2e-15 | 52.7 | In-house | 34-156 (314) | alignment | ||
Range on Protein: 975-1076
Range on HMM: 34-156/314.0
SDHTVTVGLTPSNKLLNRFANIVVYDdNRITLRPMPGhKDctNEYINACFIKDYsnqYQYIATQGPVSNTLVDF----------WQLI--WQEKSTIIVM
...|..|. . |. ||. .|. .| || | .|. .. |||| ... . ..|||||| ..|.||| |... .. .. .|||
peltilvadlflnrdknryldilpad.nrvilpglpv.sg..sdyinasyvdgf...lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivm
---------------------ITNIIEEGkvkcqQ
.... . |
srdevladelsrLdaAlgKtpllildgng.....n
|
|||||||||
| subfamily_PTPN1_pd | Subfamily PTPN1 | 23-154 | 5e-15 | 50.0 | In-house | 132-267 (290) | alignment | ||
Range on Protein: 23-154
Range on HMM: 132-267/290.0
EYNIILLNEETFNGYIERKFEVKNNNTGATQSVTQYQITNWDSTGKLTNPQTILLVIEEMYRTQR-KRGNTSIVVHCSDTVGRSAMFCAAATTIN---KC
.... |..||. . |. |..|..| .| |...... | | | |.. | . .. .. .. |.||| .||| || . | . |
klkvkliseerksyytvrllelenlktqetreilhfhyttwpdfgvpespaaflkflfkvresGslssdvGpavihcsaGiGrsGtfclvdtclvliekk
KTEGVIDVFQVLKSQRIQKPGSVQTVDRIIPDYFMI
. .|. .|| | .. | .|| |.. |. |
ddlssvdikkvllelrkyrlGliqtadqlrfsylai
|
|||||||||
| 0036282 | (Phosphotyrosine protein) phosphatases II | 48-144 | 6e-15 | 50.8 | In-house | 62-156 (174) | alignment | ||
Range on Protein: 48-144
Range on HMM: 62-156/174.0
NTGATQSVTQYQITNWDSTGKLTNPQtILLVIEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKtEGVIDVFQVLKSQRIQKPGSVQTV
. .... ||. ..|. | . .. .| ....... . . .. ..|||| |||.....|| . . |...|........| |.||.|||
redlerlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtp
|
|||||||||
| subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 990-1082 | 7.1e-15 | 49.4 | In-house | 58-146 (305) | alignment | ||
Range on Protein: 990-1082
Range on HMM: 58-146/305.0
LNRFANIVVYDDNRITLRPMPghkdcTNEYINACFIK-DYSNQYQYIATQGPVSNTLVDFWQLIWQEKSTIIVMITNIIEEGKVKCQQYWPNSD
||.... . | . . | . .|| | .. . ..|..|||. .|. .|| .. |.| |||. . .| ||.|| |||| .
knryqdvpcqdqsavkldkps.....psdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkveqivmlcktvelgklkcaqywpaaq
|
|||||||||
| subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 1098-1299 | 7.9e-15 | 49.7 | In-house | 47-256 (290) | alignment | ||
Range on Protein: 1098-1299
Range on HMM: 47-256/290.0
DYINAVFINgYKEKKAFIIAESPMFNT-------ARNFWKMIDDRNVTAIVMLCQENKNNQE----VCYQYWSNRKL-----GEYNISLlNEEIHNAGYI
||| | .. . . ..|. .|| .. .|| |. . .|. .||||. ...... | .| .. . ... . ... . .
dyiHAnrvt.cpnglrliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCakYvpesvgeelkfkgltvkC.kskekeddve
ERKIEVTNDNKagDKQQVKQYQITNWDSTGKLTNPQTILLVIEEMyrtqrKRGNTSIVIHCSDTVGRSGVFCAAATTINKCK-TEGVIDVFQVLKSQRIQ
.|...|. |.. . .|. ... .|... ...|.| .|. . | .| ...|| | . || .. | | |.| . . .|||. | |
tRelvvkfdde..eeftvtHsllkgWnklnvqedtktllsliqkv.....kasktpvivHcvdGiSrsAalaaiilgyQkiaetsgsvkledvlkalrkq
KPGSVQTVQQYQGIFQIVL
. ... ... . ..
ralaitsalelafvdagiv
|
|||||||||
| subfamily_PTPN9_pd | Subfamily PTPN9 | 22-147 | 9.1e-15 | 49.4 | In-house | 142-279 (297) | alignment | ||
Range on Protein: 22-147
Range on HMM: 142-279/297.0
GEYNIILLNEETFNGYIERKFEVKNNNTGATQSVTQYQITNWDSTGKLTNPQTILLVIEEMYRTQR---------KRG---NTSIVVHCSDTVGRSAMFC
|.... .. |. . | .|..|.|| .|. ...|| .|.. | | . ...| |.|.. ..| ..| . |||||| .||. |.
gdlsvsnveveeeedykvrvleiknvkteesrkvthfqflsWPdyGvPssaaslldvlekvrekqalavkelgdewkghpsgPPivvhcsaGiGrtGtfi
AAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVDRI
. .... ...|..||....| | |. |.|| ..
tldiclsrleevgtvdvvetvkllrtqrafsiqtpeqy
|
|||||||||
| subfamily_egg_pd | Subfamily egg | 978-1084 | 1.3e-14 | 48.6 | In-house | 31-133 (307) | alignment | ||
Range on Protein: 978-1084
Range on HMM: 31-133/307.0
TVTVGLTPSNKLLNRFANIVVYDDNRITLRPMPGHkdCTNEYINACFIKDYSNQYQYIATQGPVSNTLVDFWQLIWQEKSTIIVMITNIIEEgkVKCQQY
..| .. |. | . | |..|. | ....| | .| ..| .| |. || |||....||. |||.| | .|. |
slttaasdnnlekarskrvhckdssrvklelrrGq..ylddfihanrvkGkpllnefilaqaplkntvddfwrmvfqeevqyivmltsrkes..erceyy
WPNSDTK
||.....
wpkaesd
|
|||||||||
| subfamily_PTPRN_pd | Subfamily PTPRN | 23-146 | 1.4e-14 | 48.5 | In-house | 156-280 (297) | alignment | ||
Range on Protein: 23-146
Range on HMM: 156-280/297.0
EYNIILLNEETF-NGYIERKFEVKNNNTGATQSVTQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKRGnTSIVVHCSDTVGRSAMFCAAATTINKC-KT
|.. |. | . . |. | | .|| .| |..|||. | ..| ......| . .. | | ..||||||| .||. .... .|. |
iyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrGrs.cpivvhcsdGaGrtGvyilidlvlnrllkG
EGVIDVFQVLKSQRIQKPGSVQTVDR
||. |. | |.|| |.| |.
vkeidiaatlehlrdqrpglvktkdq
|
|||||||||
| fn3 | Fibronectin type III domain | 688-761 | 1.4e-14 | 47.2 | Pfam-A | 9-84 (85) | alignment | ||
Range on Protein: 688-761
Range on HMM: 9-84/85.0
YAKNPDAISIVWNPPTIPNGIITVYEIRYRESTSTG-PYNITNTTNT-YYSIVGLIPNTSYTIEVRAYTSIGPGEW
. ... ... |.||. ..| || ||..|||..... . ..|.. .| . . || |.|.|...|.|.. | |..
sevtstsltlsWsppkdgggpitgYeveyrekgggeewkeftvprtttsvtltgLkpgteYefrVqavngagegpe
|
|||||||||
| subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 1196-1302 | 1.4e-14 | 48.3 | In-house | 88-194 (440) | alignment | ||
Range on Protein: 1196-1302
Range on HMM: 88-194/440.0
KQQVKQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKRGNTSIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIF
. .|||. | | .| .|... .| | || ...||| .||.|| | . . ..| ||.| ...| | ..| ||| .|| ..
srtlkqyhyqgwpdkgvpkfagpvlkmiqdvnesqekagngpllvhcsagagrtgviiavdsilreakrsdqidifsfinsmrnnrpqmvqtpeqyafvh
QIVLTYL
. || |
eavlegl
|
|||||||||
| subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 1095-1301 | 3.1e-14 | 47.3 | In-house | 77-289 (310) | alignment | ||
Range on Protein: 1095-1301
Range on HMM: 77-289/310.0
EHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSNRKLGE----YNISLLNEEIHNAGYIERKIEVTND
. ||| | ... ...|| .. |. | .||.|| . .|..||. .. . | || . | .. |.| .. . . |
ryedyihanyvktnylrstficsqgplqhtiidfwrmifqeraesilllckvgeegrpkcvgywpslgvtetygcirvtnlsesseefeicnlavtfvpd
NKAGDKQQVK--Q--YQITNWDSTGKLTNPQTILLVIEEMYRTQRKRGNtsIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQ
| |.| . . .. .| |. . . .| . | |.||| ..| .| .| .|.| . .|. .| . .. .|
nvpvdeqpanlkelrvslikwpnwpdrgvpdekchtvpqrllaqvrhgp..cvvhcsagkdrlyvvvalklkidkldrglkvdaeevktellksraiciq
TVQQYQGIFQIVLTY
| || | .. . .
telqyliidrvriif
|
|||||||||
| fn3 | Fibronectin type III domain | 584-667 | 4.4e-14 | 45.6 | Pfam-A | 2-83 (85) | alignment | ||
Range on Protein: 584-667
Range on HMM: 2-83/85.0
PVGDIIFSSVESVSMTVSWDEVPcnGRNGPITGYYLTYTNITSNT-SYTVNITGEDNrMYNLTGLVPYTNYTVSIIPYNYNMNGP
..... .|.| | |.|.||.. . ..|||||| ..| . ... . ...... . ..|||| |.|.|.... .| . .||
aPenlsvsevtstsltlsWsppk..dgggpitgYeveyrekgggeewkeftvprttt.svtltgLkpgteYefrVqavngagegp
|
|||||||||
| 0051429 | (Phosphotyrosine protein) phosphatases II | 18-152 | 7.7e-14 | 47.5 | In-house | 84-225 (272) | alignment | ||
Range on Protein: 18-152
Range on HMM: 84-225/272.0
GMILGEYNIILLNEETFNGYIERKFEVKNN-NTGATQSVTQYQITNWDSTGKLTNPqtILLVIEEMYRtqrkrgNTSIVVHCSDTVGRSAMFCAAATTIN
. .| . ..|| ||... || |...... ..|.. |.... |.| | ... .| ..|.. . . ..|||| ..|.....|. .
tilygalrvtllseellldyilrellltlllsagearevmhlhytdwpdhgvpqea..llellellld......ggpvlvHCsaGkdRTGtvvallllll
KCKTEGVID--------VFQVLKSQRIQKPGSVQTVD------RIIPDYF
| ..| ...... | | ||.||| . ... ...
gvsletivddYlltnlyleeaveelraqrpgavqteeqylflyeallell
|
|||||||||
| 0051429 | (Phosphotyrosine protein) phosphatases II | 1017-1082 | 7.7e-14 | 47.5 | In-house | 4-71 (272) | alignment | ||
Range on Protein: 1017-1082
Range on HMM: 4-71/272.0
NEYINACFIKDYsnqYQ------YIATQGPVSNTLVDFWQLiWQEKSTIIVMITNIIEEGKVKCQQYWPNSD
. |||| ... | .. .....|| .| |||.| .... . ||.... | |..|| .|||. .
sgyiNardvggy...grvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgir
|
|||||||||
| I-set | Immunoglobulin I-set domain | 832-920 | 7.8e-14 | 43.2 | Pfam-A | 1-90 (90) | alignment | ||
Range on Protein: 832-920
Range on HMM: 1-90/90.0
PVIEEFPNDMTSEEGRQVLFKVKvkVRGNSKPSFNWYHNGEPVTDDYAHELRGDG---SLLLVSVEEKHKGTYRFVANNDAGTVSQQVVLTV
|.... ..|.. .|| .| .... |.|. .||..|...|.... . .... .. .| . .||.. .|.|. .|.| ||...... |.|
pkftqklkdvevseGesvelect..veGepepsvsWakdgselkssqrvkvtveeaeytLtIsnvevsDeGkYtckatnsagkaeakaeLkV
|
|||||||||
| subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 22-147 | 1.5e-13 | 45.4 | In-house | 123-253 (270) | alignment | ||
Range on Protein: 22-147
Range on HMM: 123-253/270.0
GEYNIILLNEETFNGYIERKFEVKnnNTGATQSVTQYQITNWDSTGKLT------NPQTILLVIEEMYRTQRKRGN-TSIVVHCSDTVGRSAMFCAAATT
|. ... |.|| .||| .. ... ..| .. .. .. ..| | . ... .| ..... |.... . . ..||||. |||. .. | ..
gkikvlalseekeegyiltrlrle..ekgeerrlvHfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcsaGvgRtGtlialDia
INKCKTEGVIDVFQVLKSQRIQKPGSVQTVDRI
.. .... .|| .... | ... ||.....
vrlLeetkkvdvlaiieelRkdRmalvqhpeqy
|
|||||||||
| subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 1096-1302 | 2.3e-13 | 44.3 | In-house | 74-285 (302) | alignment | ||
Range on Protein: 1096-1302
Range on HMM: 74-285/302.0
HPDYINAVFINGYKEKKAFIIAESPMFNTA---RNFWKMIDDRNVTAIVMLCQENKNNQeVCYQYWS--NRKLGEYNISLLNE----EIHNAGyIERKIE
.|.|| .. . .. |.| | ... .||.|. ..... .|.| .|.. .. ... . ||. .| . ... . ||
pdsyvnaskvevPeltrsiilaQlpkvdsedsveeFWrmvfqekivsvvilvgeeelkk.tlselfpkksgdykeygkmfvNnrkVekaeeek.tryviE
VTNDNKAgDKQQVKQYQITNWDSTGKLTNPQTILLVIEEMYRTqRKRGNTSIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQ
| .. . . .. | .||| .. ... .. ..... .. ..|| .|| |.| ..|....| ... . ...|| | |.| .|.
vlPegcs.nsvlanvyvltnWkqkkvpvkyaeliktaakvfak.kikadentvivSknGaGRagafltlavaveklqkgkepnikeivksiRsqRpravd
TVQQYQGIFQIVLTYL
...|| .. ..|.|.
slkQyvslyialllyi
|
|||||||||
| subfamily_CG7180_pd | Subfamily CG7180 | 49-146 | 2.5e-13 | 44.3 | In-house | 176-278 (296) | alignment | ||
Range on Protein: 49-146
Range on HMM: 176-278/296.0
TGATQSVTQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKRG-----NTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQT
. | |...|.| |.. |. . |. . .. |. |.. . .||..|| ..|| ...|. .... . |. .|||. .| |...|. |..
kaetRivklfqlteWeledkvPlstnalielrrrvrlwrekvdedpeegPvvvvssdGasRsGvylaidanlelvekeeevdvFeavktlrrsRpqLven
VDR
|.
vee
|
|||||||||
| subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 988-1078 | 2.6e-13 | 44.4 | In-house | 44-128 (312) | alignment | ||
Range on Protein: 988-1078
Range on HMM: 44-128/312.0
KLLNRFANIVVYDDNRITLRpmpGHkdcTNEYINACFIKDYSNQYQYIATQGPVSNTLVDFWQLIWQEKSTIIVMITNIIEEGKVKCQQYW
| |||. || ..| |.|| | | || | |.| .. ....||||. || . |||| || |.... ..|.| || .|
kdlnrypniqcwdrgrftla...gd...enfyihanfvkictkperfvctqgplentcthfwqlalslgstsiillcgfvedgsekcakyi
|
|||||||||
| 0048076 | (Phosphotyrosine protein) phosphatases II | 1181-1299 | 3.1e-13 | 45.1 | In-house | 30-140 (145) | alignment | ||
Range on Protein: 1181-1299
Range on HMM: 30-140/145.0
IERKIEVtNDNKAGDKQQVKQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKrgNTSIVIHCSDTVGRSGVFCAAATTINkcktEGvIDVFQVLKSQRIQ
| . . . ... . .... ||. ..|. | . ....| ..| . . ... . ...||| |||.|...|| . .| ......|. | |
ittvlnl.tselellerlgiqylylpwpDhgvpdllellleflefieealke..ggpvlVHCsaGvgRtgtlvaaylmll....lg.vsleealelvrsq
KPGSVQTVQQYQGIFQIVL
||.|....|.. ... .|
rpgavpnpgqlrflyefel
|
|||||||||
| 0043147 | (Phosphotyrosine protein) phosphatases II | 45-145 | 4.6e-13 | 44.7 | In-house | 55-148 (172) | alignment | ||
Range on Protein: 45-145
Range on HMM: 55-148/172.0
KNNNTGATQSVTQYQITNWDSTGKLtNPQTILLVIEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTInkckteG-ViDVFQVLKSQRIQKPGSVQT
.. .. .... ||. ..|. | ... .| ..| ... . .. . ..|||| |||.....|| . . ....... | ..||.||.
lydpellerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml......lgl.sleeavalvrekRpgavqn
VD
.
ps
|
|||||||||
| 0048179 | (Phosphotyrosine protein) phosphatases II | 1132-1295 | 7.5e-13 | 43.9 | In-house | 25-138 (144) | alignment | ||
Range on Protein: 1132-1295
Range on HMM: 25-138/144.0
IDDRNVTAIVMLCQENKNNQEVCYqywsnrklgeynisllneeihnagyierkievtndnkagdkqqVKQYQITNWDSTGKLTNPQTILLVIEEMYRTQR
. . ..|... |. | .. . .. . ||. ..|. | . .. .| ..| . . ..
lkklgittvinlteeyepeflere...........................................giqylhlpwpDhgvpdllellleflefieeale
krGNTSIVIHCSDTVGRSGVFCAAATTInkckTEGvIDVFQVLKSQRIQKPGSVQTVQQYQGIF
. ...||| |||.|...|| . ..| ......|. | . ||.|.. .|.. .
..eggpvlVHCsaGvgRtgtlvaaylmk....klg.lsleealalvrsrrpgavpnpgqlrfLl
|
|||||||||
| 0046846 | (Phosphotyrosine protein) phosphatases II | 1016-1080 | 1.6e-12 | 43.0 | In-house | 11-71 (176) | alignment | ||
Range on Protein: 1016-1080
Range on HMM: 11-71/176.0
TNEYINACFIKDYsnqyQYIATQGPVSNTLVDFWQLIWQEKSTIIVMITNIIEEGKVKCQQYWPN
|||| .| . .||||||. .|| ||........ |..|..|. .| |..|| .|||
dldyinanlilgs....rpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpe
|
|||||||||
| subfamily_hpo-7_pd | Subfamily hpo-7 | 1116-1301 | 2.5e-12 | 41.3 | In-house | 42-226 (263) | alignment | ||
Range on Protein: 1116-1301
Range on HMM: 42-226/263.0
IaespMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSNRKLGE-----YNISLLNeEIHnaGYIERKIEVTN--DNkAGDKQQVKQYQITNWD
. . .| .|...| . . .|||| | ...| | .|. | . |.. . .. . . .|... .. ..||.|. . |
l....lvqtidkfyqtivqtktevvvmLcDfneegvekcssyfPlekdekqklanvnvcttk.vqs..dvllktlellstlge.KkkthtvkhysykgWi
STGKLTNPQTILLVIeemyRTQRKRgnTSIVIHCSDTVGRSGVFCAAATTIN-------KCKTeGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTY
. .... || .. . |. |.|.||| .||| | | . . .| . .| ..|. | .......| | . .||..
ekndpelareilnil....kvarns..kslvvhcstGiGrsaafsvaElvyqkmirsldttst.veldylsLleelrssrkraihtPmqLafsilmvLdf
|
|||||||||
| subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 972-1082 | 2.7e-12 | 40.7 | In-house | 35-157 (349) | alignment | ||
Range on Protein: 972-1082
Range on HMM: 35-157/349.0
SGESDHTVTVGLTPSNKllNRFANIVVYDDNRITLRPMP----GHKD-------C-TNEYINACFIK--DYSNQYQYIATQGPVSNTLVDFWQLIWQEKS
| | .. |. | ||. .|. |. |. |. . . | . ..|||| ..| .| . .||||| |. |. ||...| ..
seiddvilseGvelfak..nrykdilPyehsrvklkkslksskvikastsesdsgklddyinanylkltrisvekkyiatqaPlPstvddfykvillngv
TIIVMITNIIEEGKVKCQQYWPNSD
... ... |.. ||..|| . .
klvlsLnddkelslekcdiywqels
|
|||||||||
| 0049260 | (Phosphotyrosine protein) phosphatases II | 1025-1078 | 2.8e-12 | 42.1 | In-house | 2-55 (152) | alignment | ||
Range on Protein: 1025-1078
Range on HMM: 2-55/152.0
IKDYSNQYQYIATQGPVSNTLVDFWQLIWQEKSTIIVMITNIIEEGKVKCQQYW
|. | .....|||||| .||| |||..... . |.|||.|. | ||.|| ||.
idgyampfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi
|
|||||||||
| subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 1117-1302 | 3e-12 | 41.2 | In-house | 39-221 (255) | alignment | ||
Range on Protein: 1117-1302
Range on HMM: 39-221/255.0
AespmfnTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSNRKLGEY-----NISLLNeeiHNAGYIERKIEVTNDNK-AGDKQQVKQYQITNWDST
| .|...| . . .|||| . ...| | .|. | . |.. . | . | .|.| ..|| |. . |
l......tvdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdeklkladvnvtttk...ssadvvlrtleitstlgekkkthtvkhysykGWiek
GKLTNPQTILLVieemYRTQRKRgnTSIVIHCSDTVGRSGVFCAAATTIN-------KCKTeGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYL
... || . .. |. |.|.||| .||| | | . .| . .| ..|. | .......| | . .||...
naPelareilni....lkvvrds..ksvvvhCstGiGrsaafvlaelvyqkmirsldttet.veldylslleelrskrkraihtPlqlafsilmvldlv
|
|||||||||
| subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 41-146 | 3.2e-12 | 40.6 | In-house | 266-373 (392) | alignment | ||
Range on Protein: 41-146
Range on HMM: 266-373/392.0
KFEVKNNNTGATQSVTQYQITNWDSTGKLT--NPQTILLVIEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKP
| . ... |. .|||||. | | ...| .| . . .. . ||.||| ||. .||.| | . .|.|| .| | ..
kqlkefrslkashtvtqyqfhgwpkhgsdqqsgarsllkliravkgstnskkefsilvhclsgagrtgvfctameciaqiaegdsvdifqtvkilradrm
GSVQTVDR
.||| .
qfvqteee
|
|||||||||
| subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 1019-1084 | 4.7e-12 | 40.3 | In-house | 77-142 (301) | alignment | ||
Range on Protein: 1019-1084
Range on HMM: 77-142/301.0
YINACFIKDYSNQYQYIATQGPVSNTLVDFWQLIWQEKSTIIVMITNIIEEGKVKCQQYWPNSDTK
| | .|. . ..||||||..|| ||| .. | . |||... .|. . ||..| | . ..
PihanwiptsGhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkise
|
|||||||||
| 0041856 | (Phosphotyrosine protein) phosphatases II | 49-159 | 9e-12 | 40.4 | In-house | 73-172 (182) | alignment | ||
Range on Protein: 49-159
Range on HMM: 73-172/182.0
TGATQSVTQYQITNWDSTGKLTnPQTILLVIEEMYRtqrkrGNTSIVVHCSDTVGRSAMFCAAATTINKckteGvIDVFQVLKSQRIQKPGSVQTVDRII
. .. ..||. ..|. | . ....| |||... . ..|||| |||.....|| . . | .......| | ..||.|.| . ..
ellerlgiqylylpwpDhgvpd.ldelldfieevle.....eggpvlVHCsaGvgRtgtlvaaylmkkl....g.vsleeavklvrsrRpgmvitpnqyf
PDYFMIYASQF
. ... .
flqlallelll
|
|||||||||
| 0036282 | (Phosphotyrosine protein) phosphatases II | 1017-1080 | 1e-11 | 40.3 | In-house | 2-60 (174) | alignment | ||
Range on Protein: 1017-1080
Range on HMM: 2-60/174.0
NEYINACFIKDYSNQYQYIATQGPVSntlvdFWQLIWQEKSTIIVMITNIIEEGKVKCQQYWPN
. |||| ... . .||.||| . ||........|..|| .. .| |..|| .|||
sdyinaspldlsyitprliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe
|
|||||||||
| subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 982-1086 | 1.2e-11 | 38.7 | In-house | 91-186 (244) | alignment | ||
Range on Protein: 982-1086
Range on HMM: 91-186/244.0
GLTPSNKLLNRFANIVVYDDNRITLRpmpgHKDCTNEYINACFIKDYSNQYQYIATQGPVSNTLVDFWQLIWQEKSTIIVMITNIIEEgkvkcQQYWPNS
. |.| || . . .| ||. | . | |||| |. .|| || |...| .|||... . . ..|.. . || ..|||.|
afnpnnswknregaglpfdfnrvpls....kgsmgntyinasfvgclgrtaeyiltqhpladtsmdfwkmmlerhvnvlvvlgsveee.....deywpds
DTKDY
. ..
eplew
|
|||||||||
| 0043147 | (Phosphotyrosine protein) phosphatases II | 1017-1080 | 1.3e-11 | 40.0 | In-house | 5-73 (172) | alignment | ||
Range on Protein: 1017-1080
Range on HMM: 5-73/172.0
NEYINACFIKDYSNQYQYIATQGPVSNTLVDFWQLIWQEKSTIIVMITNI-----IEEGKVKCQQYWPN
. |||| ... | ..|||||| .||| |||....... |.||..|. .| . .|.|
sdyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltellydpellerlgiqylylpw
|
|||||||||
| subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 987-1081 | 1.5e-11 | 38.9 | In-house | 43-131 (288) | alignment | ||
Range on Protein: 987-1081
Range on HMM: 43-131/288.0
NKLLNRFANIVVYDDNRITLRpmpghkDCTNEYINACFIKDYSNQYQYIATQGPVSNTLVDFWQLIWQEKSTIIVMITNIIEEGKVKCQQYWPNS
| .|. |. | |. | | .. ||.| . .. . | .| |. |. .|... .. |||.....| || | ..|.|
nptrdryenlprcditrvkls......ddpdfyiaanvvssakykrrlicaqaPlngtieelWkmllesdveyivmlcellekGkeksaeyfPsk
|
|||||||||
| subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 1225-1301 | 1.8e-11 | 38.4 | In-house | 219-294 (297) | alignment | ||
Range on Protein: 1225-1301
Range on HMM: 219-294/297.0
EMYRTQRKRgNTSIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTY
| .|.. | |. ...||| |||||| . . ..| . . . || .|. | |.. |||..|.. ....||
eslraempr.nayllvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqtleqfellydavlkk
|
|||||||||
| subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 26-147 | 2e-11 | 38.5 | In-house | 109-229 (239) | alignment | ||
Range on Protein: 26-147
Range on HMM: 109-229/239.0
IILLNEETFNGYIERKFEVKNNNTGATQSVTQYQITNWDSTGKLTNpQTILLVIEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVID
. | . | | || | | . . . | ||..| | | | .| . . | |.||| |||. | . . ..| . .|
vtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqy.atavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlrqakkqktvd
VFQVLKSQRIQKPGSVQTVDRI
.|. .|. | ..| ||| ..
ifnyvkairedrphmvqtseqy
|
|||||||||
| subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 26-147 | 2.1e-11 | 38.5 | In-house | 110-230 (239) | alignment | ||
Range on Protein: 26-147
Range on HMM: 110-230/239.0
IILLNEETFNGYIERKFEVKNNNTGATQSVTQYQITNWDSTGKLTNpQTILLVIEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVID
. | . | | || | | . . . | ||..| | | | .| . . | |.||| |||. | . . ..| . .|
vtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqy.atavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlrqakkqktvd
VFQVLKSQRIQKPGSVQTVDRI
.|. .|. | ..| ||| ..
ifnyvkairedrphmvqtseqy
|
|||||||||
| 0049260 | (Phosphotyrosine protein) phosphatases II | 26-145 | 2.1e-11 | 39.2 | In-house | 37-137 (152) | alignment | ||
Range on Protein: 26-145
Range on HMM: 37-137/152.0
IILLNEETFNGYIERKFEVknnntgatqsvtQYQITNWDSTGKLTNPQTILLVIEEMYRTqRKRGNTSIVVHCSDTVGRSAMFCAAATTInkckteGVID
|. |.|.. .|.. .. ||. ..|. | ...| .| ... . . ... . ..|||| |||.....|| . ..
ivmltellelgklkceqyi............qylhlpwpDhgvpdlsqlllflllfiekl.aldkggpvlVHCsaGvgRtgtlvaaylml......lgvs
VFQVLKSQRIQKPGSVQTVD
...... | ..||.|.. .
leeavalvrekRpgavpnpg
|
|||||||||
| 0048076 | (Phosphotyrosine protein) phosphatases II | 36-145 | 2.1e-11 | 39.2 | In-house | 28-130 (145) | alignment | ||
Range on Protein: 36-145
Range on HMM: 28-130/145.0
GYIERKFEVKNNNTGATQSVTQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKrgNTSIVVHCSDTVGRSAMFCAAATTINkcktEGvIDVFQVLKSQRI
| . . . .. .. .. ..||. ..|. | . ....| ..| . . ... . ..|||| |||.....|| . .| ......|. |
lgittvlnltselellerlgiqylylpwpDhgvpdllellleflefieealke..ggpvlVHCsaGvgRtgtlvaaylmll....lg.vsleealelvrs
QKPGSVQTVD
| ||.|....
qrpgavpnpg
|
|||||||||
| subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 20-148 | 2.2e-11 | 38.5 | In-house | 99-229 (237) | alignment | ||
Range on Protein: 20-148
Range on HMM: 99-229/237.0
ILGEYNIILLNEETFNGYIERKFEVKNNNTG-ATQSVTQYQITNWDSTGKLTNPQTILLVIEEMYRTQRK-RGNTSIVVHCSDTVGRSAMFCAAATTINK
| . . | .| | | | . . .. | . . |||.| | | . ..| .. .. . ..||| |||...| . . .
aygvltvslkkkeefsdytvrslllskrltlkevrlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlrq
CKTEGVIDVFQVLKSQRIQKPGSVQTVDRII
.| . |.|... ..| ..| .|| |. .
akekkvvdiynyvysieedrpyiiqtkdqyv
|
|||||||||
| subfamily_Sponge-PTP3_pd | Subfamily Sponge-PTP3 | 943-1039 | 3.4e-11 | 37.2 | In-house | 5-95 (95) | alignment | ||
Range on Protein: 943-1039
Range on HMM: 5-95/95.0
IPVDKFGEFVANGHAKGNEGFRNQFGMLDSgESDHTVTVGLTPSNKLLNRFANIVVYDDNRITLRpmpGHKDctNEYINACFIKDYSNQYQYIATQG
| | | | . |.. .. | |.| . | . ||| . .| ||| ||. || |..| ..| .||||||. |. . |||.||
ihvsvfhshvlemhsnsdqefdnefksism.tsgapytvgsseanipknrflnifpydatrvvlt...tkrd..sdyinacfvdgyarkncyiaaqg
|
|||||||||
| subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 1030-1101 | 3.9e-11 | 37.5 | In-house | 3-79 (199) | alignment | ||
Range on Protein: 1030-1101
Range on HMM: 3-79/199.0
NQYQYIATQGPVSNTLVDFWQLIWQEKSTIIVMITNIIEEGKVKCQQYWPN--SDTKDYGPFSVTLR---EHPDYIN
| .||||| |. .|. ||||..|. | |||. . . .. ||| | | || .||| . .|||
gqrryiatqhplretmadfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdyti
|
|||||||||
| subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 1097-1173 | 4.6e-11 | 37.0 | In-house | 83-165 (350) | alignment | ||
Range on Protein: 1097-1173
Range on HMM: 83-165/350.0
PDYINAVFINGY----KEKKAF--IIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSNRKLGEYNISLLNE
||||| ... . . | | . .|. .| .|.|.| .|. |..| .. .| | ||.|| . . .... | .
nDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcyrYWqegsydditvklask
|
|||||||||
| subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 1031-1102 | 4.8e-11 | 37.2 | In-house | 3-79 (198) | alignment | ||
Range on Protein: 1031-1102
Range on HMM: 3-79/198.0
QYQYIATQGPVSNTLVDFWQLIWQEKSTIIVMITNIIEEGKVKCQQYWPN--SDTKDYGPFSVTLR---EHPDYINA
| .||||| |. .|| ||||..|. | |||. . . .. ||| | | || .||| . .||| .
qrryiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytit
|
|||||||||
| subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 52-146 | 6.7e-11 | 36.2 | In-house | 88-182 (440) | alignment | ||
Range on Protein: 52-146
Range on HMM: 88-182/440.0
TQSVTQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVDR
.... ||. | | .| .|... .| | || ..|||| .||... | . . ..| ||.| ...| | ..| ||| ..
srtlkqyhyqgwpdkgvpkfagpvlkmiqdvnesqekagngpllvhcsagagrtgviiavdsilreakrsdqidifsfinsmrnnrpqmvqtpeq
|
|||||||||
| subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 1097-1162 | 7.9e-11 | 36.3 | In-house | 59-126 (297) | alignment | ||
Range on Protein: 1097-1162
Range on HMM: 59-126/297.0
PDYINAVFINGYKEKK--AFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSNRK
||||| .. .|.. .|.|. |. .| .||... ...| .|||... ... .. |. || . .
rdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrdkcapywpsvv
|
|||||||||
| 0051082 | (Phosphotyrosine protein) phosphatases II | 24-154 | 9e-11 | 37.1 | In-house | 35-149 (151) | alignment | ||
Range on Protein: 24-154
Range on HMM: 35-149/151.0
YNIILLNEETFNGYIERKFEVKNnntgatQSVTQYQITNWDSTGKLTNPQTILLVIEEMYRtqrkRGNTSIVVHCSDTVGRSAMFCAAATTINKcktegv
. |. |..|. .|| . .. . |....|..|. .| ......| ..|.. . .| ..|||| .||.....|. . .
ktivnlrseeergycpeylpelg......ievlhipildwpdpglplsfdavleflellld....kkngpvlvHCsaGkgRTGtlvalylmllg......
IDVFQVLKSQRIQKPGSVQTVDRIIPDYFMI
......|. |.. ||.||. . .. .|..
vsleealeeyrlkrpgvvqpnqqflfqlfal
|
|||||||||
| subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 6-147 | 1.6e-10 | 35.3 | In-house | 131-270 (301) | alignment | ||
Range on Protein: 6-147
Range on HMM: 131-270/301.0
KFAISIGLSTPSGMILGEYNIILLNEETF--NGYIERKFEVKNNN-TGATQSVTQYQITNWDSTGkltNPQTILLVIEEMYRTqrKRGNTSIVVHCSDTV
| . . ..... . .| ..| . |.|. . ..|..||.. ||..|| || ..| | |.. . . | |. . ||||||. .
kceeylpvkisekldigrfkikiknkelilnkkiskrtlevedstgkfatrtvthyqysewtdrg...vPkshaelfdlmelv..kksekPivvhcsaGi
GRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVDRI
||| | .. .. ... |.. . || | .. .|||. ..
Grsvafigteylareveadptieltealkhlrehrwngvqtnsql
|
|||||||||
| subfamily_eak_pd | Subfamily eak | 993-1095 | 2.2e-10 | 34.5 | In-house | 57-158 (332) | alignment | ||
Range on Protein: 993-1095
Range on HMM: 57-158/332.0
FANIVVYDDNRITLRPMPGHkdcTNEYINACFIKDYSNQYQYIATQGPVSNTLVDFWQLIWQEKSTIIVMITNIIEEGKVKCQQYWPNSD--TKDYGPFS
.|| || . . | . . |||| .. .|| | . . . |||.. ..|| ||.. . .|.. | ..|.|. ..| .
vvkivpydrylvrltssqln...rlGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledvelkleksdkyfpdktreelkfGild
VTLRE
|. .|
verke
|
|||||||||
| 0048179 | (Phosphotyrosine protein) phosphatases II | 46-145 | 2.4e-10 | 35.8 | In-house | 48-132 (144) | alignment | ||
Range on Protein: 46-145
Range on HMM: 48-132/144.0
NnntgatqsVTQYQITNWDSTGKLTNPQTILLVIEEMYRTQRkrGNTSIVVHCSDTVGRSAMFCAAATTInkckTEGvIDVFQVLKSQRIQKPGSVQTVD
. ..||. ..|. | . .. .| ..| . . .. . ..|||| |||.....|| . ..| ......|. | . ||.|.. .
e........giqylhlpwpDhgvpdllellleflefieeale..eggpvlVHCsaGvgRtgtlvaaylmk....klg.lsleealalvrsrrpgavpnpg
|
|||||||||
| subfamily_CG42327_pd | Subfamily CG42327 | 1098-1175 | 2.6e-10 | 34.5 | In-house | 57-142 (319) | alignment | ||
Range on Protein: 1098-1175
Range on HMM: 57-142/319.0
DYINAVFINGYKEKKA-FIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSNRK-------LGEYNISLLNEEI
|..| .. ||.. .. .| |. .. ... .||... ... || |.. .. .|| .|. .. |.. ..| . |.
eyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlselGikvcaeylPtketldntslyGdilvtlkgrev
|
|||||||||
| subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 18-145 | 5.8e-10 | 33.4 | In-house | 132-264 (287) | alignment | ||
Range on Protein: 18-145
Range on HMM: 132-264/287.0
GMILGEYNIILLNEETFN-GYIERKFEVKNNNTGATQSVTQYQITNWdsTGKLTNPQ---TILLVIE--EMYRTQRK-RGNTSIVVHCSDTVGRSAMFCA
| .| | ..||. . . | | . . . .| .. | |... .| | | | .|.. . .|. . .|||.. .||| .. |
PmrvGGysvvlldydikePeygvralrlidletrearvvkqldllsw..PdkvlaPtavglirfvldvkqhielardasevGPlvvhddvGiGrsGilla
AATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVD
. ... . | .|| .|. | .. . ||.|
tlvlvsrledlGrvdvaavvirlreyraalvqavv
|
|||||||||
| subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 991-1069 | 1.2e-09 | 32.1 | In-house | 41-122 (347) | alignment | ||
Range on Protein: 991-1069
Range on HMM: 41-122/347.0
NRFANIVVYDDNRITLRPMP---GHKDCTNEYINACFIKDYSNQYQYIATQGPVSNTLVDFWQLIWQEKSTIIVMITNIIEE
|| . . |. |. | | .. | .. |||| || . .|| || |. .|. |||... | | .| | . |..
nrskdvklidatrvvlspeksknsraddvetyinashikfdnaskeyiltqyplpdtvrdfwkmvsvtkvtqvvtifepikd
|
|||||||||
| 0044763 | (Phosphotyrosine protein) phosphatases II | 999-1083 | 1.6e-09 | 33.1 | In-house | 2-75 (178) | alignment | ||
Range on Protein: 999-1083
Range on HMM: 2-75/178.0
YDDNRITLRPMPGHKDctNEYINACFIKDYsnqyQYIATQGPvsntlVDFWQLIWQEKSTIIVMITNIIEEGKVKCQQYWPNSDT
.|..| | ...|. .||||..| .. |.....| .|...|..... | ||..|. .| |..|| .||| .
ldrtrvllsnlegler..sdyinaseilpg....lylgslpp.....addlellkelgithivnlteelelgflkcdpywpeeag
|
|||||||||
| subfamily_Sponge-PTP-4_pd | Subfamily Sponge-PTP-4 | 1001-1106 | 1.6e-09 | 32.1 | In-house | 7-101 (130) | alignment | ||
Range on Protein: 1001-1106
Range on HMM: 7-101/130.0
DNRITlrpmpghkdcTNEYINACFIKDYSNQYQYIATQGPVSNTLVDFWQLIWQEKSTIIVMITNIIEEgkvkcQQYWPNSDTKDYGP----FSVTLREH
.|. |.|||| |. . .|. || |...| .|||... . ..|.. . || ..|||.|. .. ..| |.
vsrlq..........gntyinasfvGllgrtaeylltqhpladtsmdfwkmmleryvnvlvvlgsveee.....deywpdsePlewyeediivtltdrde
PDYINAVFIN
..|.| ...
fknikasnle
|
|||||||||
| 0046846 | (Phosphotyrosine protein) phosphatases II | 44-145 | 1.8e-09 | 33.1 | In-house | 77-160 (176) | alignment | ||
Range on Protein: 44-145
Range on HMM: 77-160/176.0
VknnntgatqsvtQYQITNWDSTGKLTNpQTILLVIEEMYRTQRKrGnTSIVVHCSDTVGRSAMFCAAAttinKCKTEGVIDVFQVLKSQRIQKP-GSVQ
. ||. ..|. | . . .| ..|.... ... | ..|||| .||.....|| ...| ..|...|. | |.| |.||
i............qylhlpwpDhgvpdl.elllellefirealke.g.gpvlVHCsaGigRtgtlvaay....llelekglsveealalvreqRplgavq
TVD
| .
tpe
|
|||||||||
| subfamily_Sponge-PTP-4_pd | Subfamily Sponge-PTP-4 | 1092-1214 | 2.2e-09 | 31.7 | In-house | 8-128 (130) | alignment | ||
Range on Protein: 1092-1214
Range on HMM: 8-128/130.0
TLREHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNqevcyQYWSNRK-LG--EYNISLLNEEIHNAGYIERKIEVT
. . .|||| |. . .. .. |. .|. .||||. .| | .|.| .... .|| . . | | .| . . .. .|. .
srlqgntyinasfvGllgrtaeylltqhpladtsmdfwkmmleryvnvlvvlgsveeed.....eywpdsePlewyeediivtltdrdefknikasnlei
NDNKAGDKQQVKQYQITNWDSTGKLT
... .| . .||.|| | |
esdlneshqaltmfqisnwpsdgttp
|
|||||||||
| subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 1027-1093 | 3.1e-09 | 30.7 | In-house | 231-295 (440) | alignment | ||
Range on Protein: 1027-1093
Range on HMM: 231-295/440.0
DYSNQYQYIATQGPVSNTLVDFWQLIWQEKSTIIVMITNIIEEgkvKCQQYWP-NSDTKDYGPFSVTL
||.. .|||| |. |..|||.|. . . . |.|. .. . | ||| |. . .|||.|
gyskknafiatqmpldstvldfwrlvhdyristiimlnqlndk...tcsiywpvntrsvtfgpftvgh
|
|||||||||
| subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 1098-1193 | 4.8e-09 | 30.0 | In-house | 91-188 (349) | alignment | ||
Range on Protein: 1098-1193
Range on HMM: 91-188/349.0
DYINAVFIN--GYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSNRKLGEYNISLLNEEIHNAGYIERKIEVTNDNKA
||||| ... .. .| .| |. | .|.|.| .| .. | ...... | |..|| . . .... | | . |. .| .....
dyinanylkltrisvekkyiatqaPlPstvddfykvillngvklvlsLnddkelslekcdiywqelsysnitvklqnsslyianvqGnslrvstvkdt
|
|||||||||
| subfamily_PTPN14_pd | Subfamily PTPN14 | 22-144 | 6.6e-09 | 30.2 | In-house | 152-282 (300) | alignment | ||
Range on Protein: 22-144
Range on HMM: 152-282/300.0
GEYNIILLNEETFNGYIERKFEVKNNNTGATQSVTQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKRGNT--------SIVVHCSDTVGRSAMFCAAAT
|..... |. . .| .....| .. ..| | |.| | .... | .||. .|| .. ..||||. |||. . .
gkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseveskeskPPvlvhCsaGvGrtGvlilsdl
TINKCKTEGVIDVFQVLKSQRIQKPGSVQTV
|. ... .||. .||. | |. |||.
liatlehneeidikkvlarLreqrmllvqtl
|
|||||||||
| subfamily_CG42327_pd | Subfamily CG42327 | 1230-1301 | 7.5e-09 | 29.7 | In-house | 242-314 (319) | alignment | ||
Range on Protein: 1230-1301
Range on HMM: 242-314/319.0
QRKRGNTSIVIHCSDTVGRSGVFCAAATTINKCKTE-GVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTY
.. . .|.|||| |||.|. |. .|.. .. .|. |.. | | .. .|.|..||. |.... |
gtresqGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefiykvlsey
|
|||||||||
| subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 1098-1219 | 1.3e-08 | 28.8 | In-house | 123-242 (244) | alignment | ||
Range on Protein: 1098-1219
Range on HMM: 123-242/244.0
DYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQevcyqYWSNRKLGE-Y--NISLLN---EEIHNAGYieRKIEVTNDN
|||| |. .|... |. .|. .||||. .| | .|.| ..... || . . | | .|.. .|..| ..|. |
tyinasfvgclgrtaeyiltqhpladtsmdfwkmmlerhvnvlvvlgsveeede.....ywpdseplewyeeditvtltdrdefknika..snleiesdm
KaGDKQQVKQYQITNWDSTGKLTNPQTI
. .| . .||.|| | | | |
n.eshqaltmfqisnwpsdgttpndhfi
|
|||||||||
| 0051082 | (Phosphotyrosine protein) phosphatases II | 1017-1082 | 2e-08 | 29.5 | In-house | 3-57 (151) | alignment | ||
Range on Protein: 1017-1082
Range on HMM: 3-57/151.0
NEYINACFIKDYsnqyqYIATQGPVSntlvDFWQLIWQEKSTIIVMITNIIEEGkvKCQQYWPNSD
. |||. .. .. .....|| . ||..|..... . ||.... | | .| .|.|. .
sdyinfsyvtgg.....lyrsggpla....dflellkelgiktivnlrseeerg..ycpeylpelg
|
|||||||||
| subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 19-143 | 3.5e-08 | 27.4 | In-house | 148-268 (290) | alignment | ||
Range on Protein: 19-143
Range on HMM: 148-268/290.0
MILGEYNIILLNEETFNG-YIERKFEVKNNNTGATQSVTQYQITNWDSTGkLTNPQtiLLVIeEMYRTQRKRgNTSIVVHCSDTVGRSAMFCAAATTInK
. .||. .. .|.. . | . . |.. ..| . ..| | ... . | .. . |. || . .||||| .||. | | ... .
ltfGeitvlcseeddkdaniikktlsvrdkdsGkehklkhlkikswpdks.valst..lall.rtlrilrka.sGpvvvhcsaGiGrtGtfvaievgl.q
CKTEG-VIDVFQVLKSQRIQKPGSVQT
. ..| .|. .. .. | . .|||
illdGkeldlldlvralrnsrlnsvqv
|
|||||||||
| subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 45-148 | 4.9e-08 | 26.8 | In-house | 178-278 (302) | alignment | ||
Range on Protein: 45-148
Range on HMM: 178-278/302.0
KNNN--TGATQSVTQYQITNWDSTGKLTNPQTILLVIEemYRTQRKrgnTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQ
||.. . ..| . . | | ...| | .. . | ....|||| |||. . | |. |... | |. .... | . |.||
knekkkkkvkktvdilafsawpdhGapkeaytaldilk..fcesyk...knvlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavq
TVDRII
. ...|
deqqli
|
|||||||||
| subfamily_Cele-PTP-12_pd | Subfamily Cele-PTP-12 | 987-1074 | 7.7e-08 | 26.2 | In-house | 34-118 (332) | alignment | ||
Range on Protein: 987-1074
Range on HMM: 34-118/332.0
NKLLNRFANIVVYDDNRITLRPMPGHKDctneYINACFIKDYSNQYQYIATQGPVSN-TLVDFWQLIWQEKSTIIVMITNIIEEGKVKC
| .|| . ..| .|. | | |. | . || .. ||.. || .| |. . | ||... . | ..|... .| |. | |.
nmdmnriphlycfdhsrvelapqdgkdd....fynaswvdgyskksayifaqapfndhteyvfwrmvserkpsmilvfgdidekqkrka
|
|||||||||
| subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 1105-1159 | 7.9e-08 | 26.0 | In-house | 229-280 (440) | alignment | ||
Range on Protein: 1105-1159
Range on HMM: 229-280/440.0
INGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQEnknNQEVCYQYWS
..|| |.||| .. |. | .||... | ....|.|| | |. | ||
fegyskknafiatqmpldstvldfwrlvhdyristiimlnql...ndktcsiywp
|
|||||||||
| subfamily_Cele-PTP-5_pd | Subfamily Cele-PTP-5 | 1112-1302 | 8.6e-08 | 25.2 | In-house | 115-309 (346) | alignment | ||
Range on Protein: 1112-1302
Range on HMM: 115-309/346.0
KAFIIAESPMFNT---ARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSNRKLGEYNIS--LLNEEIHNAG-YIERKIEVTNDNKAgDKQQVKQYQIT
. .|.|. | .. .|| || . .. . .. ..| .. . . .| . | .| | ||| . .. | .. .. .
hklivaqlpqmenesfvedfwymiyqeqihlvylmvpddklkntttslfndenggyqytgkmfinnrradvsgdpkeytievlpegns.dsvicqvhhha
NWDSTGKLTNPQTILLVIEEMYrTQRKRGNTSIVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYL
| . . |. .| ... .... |. . . ||. | | .||. ......|. . |.||.|.. || .|. ||. |.
pwkhlqqppktlpiikmihqfl.sekqvqnagvcvvslfgcgracsfigalyainqlnngiepniceimknikqqrpggvesfaqyasiyaivfdyi
|
|||||||||
| 0044763 | (Phosphotyrosine protein) phosphatases II | 47-143 | 8.8e-08 | 27.5 | In-house | 75-156 (178) | alignment | ||
Range on Protein: 47-143
Range on HMM: 75-156/178.0
NntgatqsvTQYQITNWDSTGKLTNPQTILLVIEEMYRTQRkRGNTSIVVHCSDTVGRSAMFCAAATTINKckteGViDVFQVLKSQRIQKPgSVQT
. ||. .... | . .. .| ..| . . . . . ..|||| ||||....|| . |. ....... | ..| |..
g........iqylhipipDhgvpdllehflefvefieeald.ekggpvlVHCsaGvgRsgtlvaaylmkkl....gl.sleeaielvrerRp.ivpn
|
|||||||||
| subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 32-139 | 1.2e-07 | 26.2 | In-house | 138-240 (290) | alignment | ||
Range on Protein: 32-139
Range on HMM: 138-240/290.0
ETFNGYIERKFEVKNNNtGATQSVTQYQITNWDSTGKLTNPQTILLVIEEMyrtqrKRGNTSIVVHCSDTVGRSAMFCAAATTINKCK-TEGVIDVFQVL
|. .. ..|. .|| .. . || ... .|... ...|.| .|. . | .| ..||| | . |||.. | | |.| . . .||
ekeddvetRelvvkfdd.eeeftvtHsllkgWnklnvqedtktllsliqkv.....kasktpvivHcvdGiSrsAalaaiilgyQkiaetsgsvkledvl
KSQRIQKPG
|. | |.
kalrkqral
|
|||||||||
| 0049772 | (Phosphotyrosine protein) phosphatases II | 35-151 | 1.2e-07 | 27.2 | In-house | 167-273 (314) | alignment | ||
Range on Protein: 35-151
Range on HMM: 167-273/314.0
NgyierkfEVKNNNTGATQSVTQYQITNWDStGKLTNPQTILLVIEEMYRTqrkRGNTSIVVHCSDTVGRSAMFCAAATTINKCkteGViDVFQVLKSQR
. |. ... .. . .| .... | .. .. ..| . . . .. ..|||.. .||.. |..|| . .. || .. ..|. |
k.......eelydpelferlgikylripvpD.gsaplledfdeflefieea...dkggpvlvHCkaGkgRtgtfvvaaylmkll...gv.sleealedvr
IQKP-----GSVQTVDRIIPDY
. | |.... .. . .
lkRpinpnpgfieqleqyefil
|
|||||||||
| subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 1193-1260 | 1.7e-07 | 25.3 | In-house | 211-287 (350) | alignment | ||
Range on Protein: 1193-1260
Range on HMM: 211-287/350.0
AGDKQQVKQYQITNWDSTGKLTNPQTILLVIE--------EMYR--TQRKRGnTSIVIHCSDTVGRSGVFCAAATTIN
| | | | |. || . | ||. || ..| . . . .|. ..|..||| ||| |.... ..
asdPyvvyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnars.spilvhCsaGvGrtGtlvtlDslls
|
|||||||||
| subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 47-144 | 2.1e-07 | 25.3 | In-house | 170-263 (307) | alignment | ||
Range on Protein: 47-144
Range on HMM: 170-263/307.0
NNTGATQSVTQYQITNWDSTGkltNPQTILLVIEEMYRTQRKrgNTSIVVHCSDTVGRSAMFCAAATTINKC-KTEGVIDVFQVLKSQRIQKPGSVQTV
. .. .......| .|| | ||. | |. . .. . . .||||| |||| | . .| . . |. .... | |.. ..||
dwaqksrtiqhlqwenwpdrg...vpqinltainlleavryd..tnpvvvhcsaGvGrsGtivaislvqdkmiaGinckdmkklveelrsqrhyaiqte
|
|||||||||
| subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 36-148 | 3.3e-07 | 24.1 | In-house | 155-269 (439) | alignment | ||
Range on Protein: 36-148
Range on HMM: 155-269/439.0
GYIERKFEVKNN--NTGATQSVTQYQITNWDSTGKLTNPQTILLVIEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQ
|. | | | |. .| ..| |.. . | .. .| . . .. |. .||||| |||. | .... |.| .|. ..|
nyvirgfkvfnerdttekertvlqfhyiawpdknvpaqashvldflrainsandkeeygpvvvhcsagvGrtGtiialdialeqlklenkvdikgivkvl
RIQKPGSVQTVDRII
| |. ||.. . .
rkqrkqmvqalcqyv
|
|||||||||
| subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 1036-1081 | 3.4e-07 | 24.6 | In-house | 39-77 (255) | alignment | ||
Range on Protein: 1036-1081
Range on HMM: 39-77/255.0
AtqgpvsnTLVDFWQLIWQEKSTIIVMITNIIEEGKVKCQQYWPNS
|. |.| | | |.. .||... |||..||..|.|
l.......tvdkfyqtivqtktevvvmlcdfaeegvekcssyfple
|
|||||||||
| subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 1000-1081 | 6.2e-07 | 23.8 | In-house | 31-120 (290) | alignment | ||
Range on Protein: 1000-1081
Range on HMM: 31-120/290.0
DDNRITLRPMpgHKDCTNEYINACFIKdYSNQYQYIATQGPVSN-------TLVDFWQLIWQEKSTIIVMITNIIEEGKV----KCQQYWPNS
..|. |. | ...|| | ... ..| . |.|| | . |. .|| .. |||.. .||. . |. . |..| |.|
eatrvvLkgy..gkrfnddyiHAnrvt.cpnglrliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCakYvpes
|
|||||||||
| subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 944-1026 | 7.9e-07 | 22.7 | In-house | 7-84 (440) | alignment | ||
Range on Protein: 944-1026
Range on HMM: 7-84/440.0
PVDKFGEFVANGhaKGNEGFRNQFGMLDSGESDHTVTVGLtPSNKLLNRFANIVVYDDNRITLRPMPGHKDctNEYINACFIK
| | ..| | . | ... .| || |. . .| |.||. ||. ||..|| .|. | . | | ..|||| .|.
ivadfadyvqnn..rrsrafedewsllpsglsqpsdiasl.pnnkvknryrnilaydhsrvmleevkgvpd..sdyinasyin
|
|||||||||
| subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 987-1075 | 1e-06 | 22.6 | In-house | 47-126 (303) | alignment | ||
Range on Protein: 987-1075
Range on HMM: 47-126/303.0
NKLLNRFANIVVYDDNRITLrpmpghkdCTNEYINACFIkDYSNQYQYIATQGPVSNTLVDFWQLIWQEKSTIIVMITNIIEEGKVKCQ
| |||..... | .. | . || | .. . . . | || |.| | ||||.| ..| .... | |. .
nmdknrfvdvicldhskvkl........sdssyihasyl.eldsskkailtqlplshtaadfwqmiieqkvkcvlllltdseydklggd
|
|||||||||
| subfamily_hpo-7_pd | Subfamily hpo-7 | 1028-1081 | 1.8e-06 | 22.0 | In-house | 36-83 (263) | alignment | ||
Range on Protein: 1028-1081
Range on HMM: 36-83/263.0
YSNQYQYiatqgpVSNTLVDFWQLIWQEKSTIIVMITNIIEEGKVKCQQYWPNS
| | . .|. |.| | | |.. .||... |||..||..|.|
rknlysl......lvqtidkfyqtivqtktevvvmLcDfneegvekcssyfPle
|
|||||||||
| subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 1098-1148 | 1.9e-06 | 21.7 | In-house | 71-121 (347) | alignment | ||
Range on Protein: 1098-1148
Range on HMM: 71-121/347.0
DYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENK
|||| |. . .| .|... |. .| |.||||. .|| .| . . |
tyinashikfdnaskeyiltqyplpdtvrdfwkmvsvtkvtqvvtifepik
|
|||||||||
| subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 81-146 | 2.1e-06 | 21.8 | In-house | 219-283 (297) | alignment | ||
Range on Protein: 81-146
Range on HMM: 219-283/297.0
EMYRTQRKRgNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVDR
| .|.. | |. ..|||| |||| . . . ..| . . . || .|. | |.. |||...
eslraempr.nayllvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqtleq
|
|||||||||
| subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 54-114 | 2.4e-06 | 21.5 | In-house | 216-285 (350) | alignment | ||
Range on Protein: 54-114
Range on HMM: 216-285/350.0
SVTQYQITNWDSTGKLTNPQTILLVIE--------EMYR--TQRKRGnTSIVVHCSDTVGRSAMFCAAATT
| | |. || . | ||. || ..| . . . .|. ..|.|||| ||| ....
vvyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnars.spilvhCsaGvGrtGtlvtlDsl
|
|||||||||
| subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 58-156 | 3e-06 | 20.9 | In-house | 186-279 (302) | alignment | ||
Range on Protein: 58-156
Range on HMM: 186-279/302.0
YQITNWDSTGKLTNPQTILLVIEEMYRTQrKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVDRiipdYFMIYA
| .||| .. ... .. ..... . .. ..|. .|| ..| ..|....| ... . ...|| | |.| .|.... | ..|
yvltnWkqkkvpvkyaeliktaakvfakk.ikadentvivSknGaGRagafltlavaveklqkgkepnikeivksiRsqRpravdslkQ....yvslyi
|
|||||||||
| subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 1198-1260 | 3e-06 | 20.8 | In-house | 219-290 (349) | alignment | ||
Range on Protein: 1198-1260
Range on HMM: 219-290/349.0
QVKQYQITNWDSTGKLTNPQTILLVIE-------EMY-RTQR-KRGNTSIVIHCSDTVGRSGVFCAAATTIN
.. | |. || .. | ||..|| .| ... | . .....||| ||.||.. ..
ellqlqvknwldlslllnPisilqalevkndliddlfarlyldtdqlstllvhcsaGcGrtGvlvtldllls
|
|||||||||
| subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 51-148 | 3.2e-06 | 21.4 | In-house | 114-211 (255) | alignment | ||
Range on Protein: 51-148
Range on HMM: 114-211/255.0
ATQSVTQYQITNWDSTGKLTNPQTILLVieemYRTQRKRgnTSIVVHCSDTVGRSAMFCAAATTIN-------KCKTeGVIDVFQVLKSQRIQKPGSVQT
|. |. |. . | ... || . .. |. |.||||| .|||| | | . .| . .| ..|. | .......|
kthtvkhysykGWieknaPelareilni....lkvvrds..ksvvvhCstGiGrsaafvlaelvyqkmirsldttet.veldylslleelrskrkraiht
VDRII
..
Plqla
|
|||||||||
| Ig_3 | Immunoglobulin domain | 832-907 | 3.5e-06 | 19.1 | Pfam-A | 2-75 (75) | alignment | ||
Range on Protein: 832-907
Range on HMM: 2-75/75.0
PVIEEFPNDMTSEEGRqvlFKVKVKVRGNS-KPSFNWYhNGEPVTDDYAHELRGDGSLLLVS-VEEKHKGTYRFVANN
||| |. .....| .. ..|.. .|.. || ...| .. . ... .| | .| | ... |||. ||.|
Pvisvspsptvtsggn...vtLtCsaeggpppptisWy.ietppelqgsegssssestLtissvtsedsGtYtCvasN
|
|||||||||
| subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 46-144 | 3.8e-06 | 21.2 | In-house | 86-190 (199) | alignment | ||
Range on Protein: 46-144
Range on HMM: 86-190/199.0
NNNT--GATQSVTQYQITNWDST--GKLTNPQTILLVIEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTIN---KCKTeGVIDVFQVLKSQRIQKP
|| | .|. ...||.| | ... ... |. . . .. ..||||| | . .| | . . || |.|.|.| | | .
nnttappstreishyqftswkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheeskt.svvdlfevakrlrqarc
GSVQTV
| . ..
giissl
|
|||||||||
| subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 46-144 | 3.8e-06 | 21.2 | In-house | 85-189 (198) | alignment | ||
Range on Protein: 46-144
Range on HMM: 85-189/198.0
NNNT--GATQSVTQYQITNWDST--GKLTNPQTILLVIEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTIN---KCKTeGVIDVFQVLKSQRIQKP
|| | .|. ...||.| | ... ... |. . . .. ..||||| | . .| | . . || |.|.|.| | | .
nnttappstreishyqftswkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheeskt.svvdlfevakrlrqarc
GSVQTV
| . ..
giissl
|
|||||||||
| subfamily_Cele-PTP-5_pd | Subfamily Cele-PTP-5 | 962-1068 | 4.4e-06 | 19.5 | In-house | 27-126 (346) | alignment | ||
Range on Protein: 962-1068
Range on HMM: 27-126/346.0
GFRNQFGMLDSGESDHTVTVglTPSNKLLNRFANIVVYDDNRITLRpMPGHKDCtnEYINACFIKDySNQYQYIATQgPVSNTLVDFWQLIWQEKSTIIV
|..||.||| ..|. .||. || . .||.||. | |||.| .||||. | .. . .|. |. || .. .|.| . .||
kireefgfldslvcnktted..feankvrnregcpkiydenrvqln.rpghedv..nyinasvitl.kdvsrrmacv.payvhlvvlyfvifqfehkliv
MITNIIE
.|
aqlpqme
|
|||||||||
| subfamily_Cele-PTP-12_pd | Subfamily Cele-PTP-12 | 1097-1152 | 5.6e-06 | 20.0 | In-house | 60-117 (332) | alignment | ||
Range on Protein: 1097-1152
Range on HMM: 60-117/332.0
PDYINAVFINGYKEKKAFIIAESPMFN-TARNFWKMIDDRNVTAIVMLCQE-NKNNQE
|. || ...|| .| |.|.|..|. . | ||.|. .|. . |... . .|....
ddfynaswvdgyskksayifaqapfndhteyvfwrmvserkpsmilvfgdidekqkrk
|
|||||||||
| Ig_2 | Immunoglobulin domain | 857-920 | 6.2e-06 | 18.2 | Pfam-A | 23-80 (80) | alignment | ||
Range on Protein: 857-920
Range on HMM: 23-80/80.0
VRGNSKPSFNWYHNGEPVTDDYAHelrgdgsLLLVSVEEKHKGTYRFVANND-AGTVSQQVVLTV
..|| .|.. ||..||... . |.. .|.....|||. .| |. ...|. | .||
apgnptpkvqwykdgeelsqsqna.......lfipnvsaedsGtYtCrasnsegskqsnsvevtv
|
|||||||||
| subfamily_eak_pd | Subfamily eak | 1092-1210 | 7.4e-06 | 19.6 | In-house | 73-192 (332) | alignment | ||
Range on Protein: 1092-1210
Range on HMM: 73-192/332.0
TLREHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENKNNQEVCYQYWSNRK-----LGEYNISLLNEeIHNAGYIERKIE
. ... |||| .. . . .|.. . . ||.|. ... |||.| .. ... | .|. .. | ... . .... . |..|
sqlnrlGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledvelkleksdkyfpdktreelkfGildverkef.vkrniletrlle
VTNDNKAgdkQQVKQYQITNWDST
.. |.. .|. |.. | |
lskGnet...hrvlhykvfGwtet
|
|||||||||
| subfamily_Sponge-PTP-7_pd | Subfamily Sponge-PTP-7 | 1238-1291 | 8e-06 | 20.2 | In-house | 1-54 (69) | alignment | ||
Range on Protein: 1238-1291
Range on HMM: 1-54/69.0
IVIHCSDTVGRSGVFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQY
.|.||| ||.| | | . . |.| ..|.| .. | .| | ..|
mvvhcssgtgrtgtfiaimvemarikseklvdifnnvqymrkcrpmmvmneiey
|
|||||||||