Gene PTPRD-25 in Amphimedon queenslandica

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family PTP
Subfamily PTPRD
Protein sequence
ID Type Fasta BLAST phosphatome Note
AqueP079_AA protein Get Run
AqueP079_AA_813-998 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_Sponge-PTP11_pd Subfamily Sponge-PTP11 896-999 2.4e-55 182.5 In-house 175-278 (290) alignment
Range on Protein: 896-999
Range on HMM: 175-278/290.0
GAKQSVTQFQITNWGSTGEVKNPQTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVVSINY
||||||||.||||| |||.|.||||||...||||.||||||||||||||||||||||.|||||||||||||||||||||||||||||||||||||.....
gakqsvtqyqitnwdstgkvtnpqtillvieemyktqrkrgntsivvHCSdtvgrsavfcaaattinkcktegvidvfqvlksqRiqkpgsvqtvqqyqg

SCYI
 ..|
ifqi

subfamily_Sponge-PTP10_pd Subfamily Sponge-PTP10 895-991 5.7e-54 178.0 In-house 169-265 (287) alignment
Range on Protein: 895-991
Range on HMM: 169-265/287.0
TGAKQSVTQFQITNWGSTGEVKNPQTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVV
.|.||.|.|.||||| |||.|..|||||...||||.|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 
agdkqqvkqyqitnWdstgkvtepqtillvieemyktqrkrgntsivvhCsdtvGrsamfcaaattinkckteGviDvfqvlksqriqkpgsvqtve

subfamily_Sponge-PTP11_pd Subfamily Sponge-PTP11 810-894 9e-43 141.2 In-house 1-85 (290) alignment
Range on Protein: 810-894
Range on HMM: 1-85/290.0
LVPVGQFGEFVANGHAKGNEGFRNQFMMLDSGESDHSVTVGLTSSNKLLNRFANIVVYDDNRIILRPISGHKDCPNEYVNACYVD
|.||..||||||||||||||||||||.|||||||.|.||||||||||||||||||||||||||.||||||||||.|||.||||..
lipvdkfgefvanghakgnegfrnqfkmldsgesehtvtvgltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyik

0051299 (Phosphotyrosine protein) phosphatases II 809-995 1.1e-35 118.9 In-house 3-277 (288) alignment
Range on Protein: 809-995
Range on HMM: 3-277/288.0
NLVPVGQFGEFVANGHAKGNEGFRNQFMMLDSGESDHSVTVGLTSSNKLLNRFANIVVYDDNRIILRPISGhkDCPNEYVNACYV---------------
. ..| .. ..| . .|.|. |....| .| |   |......|   |.  ||. .|. ||..|..|....|  . .. |.|| |.               
teisveellklvlkllangltglleefeellsllpdltlsaallpenleknRysdilpydhsRVkLsvldg..vegsdYinAsyidgynlkrkfIatqgP

----------------------------------------------------------------------------DTGAKQSVTQFQITNWGSTGEVKN
                                                                             .| .. ||.|. |||   |   .
lpntvedFWrmvweqnvrvIvmltklvelgrekcaqYwplggsltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpds

PQTILMIMEEMYRTQRkRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVVSINY
|. .| ....... ..  |.  .|||||. |||...|.|. . ..  ..||..||....|  | |.||.|||.  . .
pellldflrlvrkala.sgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrf

0050432 (Phosphotyrosine protein) phosphatases II 824-992 1.4e-32 108.6 In-house 37-287 (308) alignment
Range on Protein: 824-992
Range on HMM: 37-287/308.0
HAKGNEGFRNQFMMLDSGESDHSVTVGLTSSNKLLNRFANIVVYDDNRIILrpisghkDCPNEYVNACYVDTG---------------------------
.|... ... .|. | |   ... .|.|   || .||. .|. || .|..|       | .. |.|| |||.                            
kaldlglleeefeellsvkplleysvallpenkdkNrykdilpydhsRVkl.......degsdYInAsyvdgyssklprkfIatqgPlpntvedFwrmvw

-----------------------------------------------------------------AKQSVTQFQITNWGSTGEVKNPQTILMIMEEMYRT
                                                                     ||.|. |||   |   .|. .| ..|.. ..
eqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseevlddytvrtleltnlgdgesrtvthfhytnWpdhgvPpspeilldflelvrks

QrkrGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVVS
.   ..  ||||||. |||.. |.|. . ..  ..|| .|||...|  | |.||.|||.  
l...pggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeq

0045450 (Phosphotyrosine protein) phosphatases II 811-995 7.9e-32 106.6 In-house 9-295 (307) alignment
Range on Protein: 811-995
Range on HMM: 9-295/307.0
VPVGQFGEFVANGHAKGNEGFRNQFMMLDSGES--DHSVTVGLTSSNKLLNRFANIVVYDDNRIILRPISGHkDCPNEYVNACYV---------------
... ..  .|.  ......|.. .| .| | .    .. ...|   || .||. .|. ||..|..| ...|. . .. |.|| ||               
idalkllllvllllldfltgllkefekllsvtvfllgeysiallpenkdknrykdilpydhtRVklssldgs.ledsdYiNAsyvrvpllllldgydlkr

----------------------------------------------------------------------------------DTGAKQSVTQFQITNWGS
                                                                                   ||    ||.|. |.|  
kfIatqgPlpetvedFwrmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpd

TGEVKNPQTILMIMEEMYRTQRKR-GNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGV---IDVFQVLKSQRIQKPGSVQTVVSINY
.|  ......| ..||. . ...  ... ..||||. |||...|.|| . .   ..||.   .|.....|  | |.||.||.   . .
hgvppsfeelldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrf

0046845 (Phosphotyrosine protein) phosphatases II 831-996 2.3e-31 104.7 In-house 2-266 (284) alignment
Range on Protein: 831-996
Range on HMM: 2-266/284.0
FRNQFMMLDSGESDH--SVTVGLTSSNKLLNRFANIVVYDDNRIILRPISGHkDCPNEYVNACYVD----------------------------------
.. .|..| |   ..  |..|.|   |. .||. .|..||..|..|....|. .  ..|.|| |||                                  
leeefeellsltvklllslsvallpenlsknRykdilpydhsRVklksldgd.ledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweq

------------------------------------------------------------TGAKQSVTQFQITNWGSTGEVKNPQTILMIMEEMYRTQRK
                                                            ||    ||.|..|.|   |   .|. .| ..... . ...
nvrvIVmltelvengrekcaqYwplegevltygdftvtllseevkddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrellen

-RGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEG---VIDVFQVLKSQRIQKPGSVQTVVSINYS
  |.  ||||||. |||...|.|. . ..  ..||   ..||....|  | |.||.|||.  . . 
lpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfv

0040438 (Phosphotyrosine protein) phosphatases II 815-998 2.6e-31 104.5 In-house 4-270 (317) alignment
Range on Protein: 815-998
Range on HMM: 4-270/317.0
QFGEFVANGHAKGNEGFRNQFMMLDSGESDhSVTVGLTSSNKLLNRFANIVVYDDNRIILRPISGhkDCPNEYVNACYVD--------------------
.. ...   ..... .....|..|.|   | . .|..   || .||. .|. ||..|..| |..|  | .. |.|| |||                    
dlllalldllksdftalleefedllslkld.tysvaelpenkdknrypdilpydhsRVkLsplgg..dldsdYInAsyvdgpnlkrkfIatqgPlpntve

-------------------------------------------------------------------TGAKQSVTQFQITNWGSTGEVKNPQTILMIMEE
                                                                   .. .  ||.|. |.|   |  ..|...| ..|.
dFwrmvweqgvtvivmLteleelgrekcaqYwplgetltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldflea

MYRTQRkRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVVSINYSCY
. . .. .... ..||||. |||...|.|| . .. ...|| .||....|  | |.||.|||   . . ..
vreale.dpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflyd

0047943 (Phosphotyrosine protein) phosphatases II 824-997 2.8e-31 104.4 In-house 7-265 (273) alignment
Range on Protein: 824-997
Range on HMM: 7-265/273.0
HAKGNEGFRNQFMMLDSGESDHSVTVGLTSSNKLLNRFANIVVYDDNRIILrpisghKDCPNEYVNACYVDT----------------------------
...|. ... .| .| |   ... .|.|   || .||. .|. ||..|..|      .| .. |.|| |||.                            
kllgltllleefelllslkplltysvallpenkdknrykdilpydhsrvkl......gdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvweq

--------------------------------------------------------------GAKQSVTQFQITNWGSTGEVKNPQTILMIMEEMYRTQR
                                                              | .  ||.|. |.|   |   ... .| ..|.. ....
nvrviVmLtelvelgrekcaqYwpleggelsltygkftvtllseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvrkale

KR-GNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVVSINYSC
.  .|. .|||||. |||...|.|. . ..  ..|| .||....|  | |.||.|||.  . . .
alpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrfly

0036941 (Phosphotyrosine protein) phosphatases II 825-991 4.6e-31 103.6 In-house 9-264 (297) alignment
Range on Protein: 825-991
Range on HMM: 9-264/297.0
AKGNEGFRNQFMMLDSGESDHSVTVGLTSSNKLLNRFANIVVYDDNRIILrpisghKDCPNEYVNACYVD------------------------------
.... ... .|. |..   . | .|.|   |. .||. .|. ||..|..|      .| .. |.||.|||                              
llflalllkefeellpllllgslsvallpenleknRykdilpydhtRVkl......ddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqn

-------------------------------------------------------------TGAKQSVTQFQITNWGSTGEVKNPQTILMIMEEMYRTQR
                                                             .| .  ||.|..|.|   |   .|...| ..|.. . ..
vtvIvmltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrkvlk

KR-GNTSIVVHCSDTVGRSAMFCAAATTINKCK---TEGVIDVFQVLKSQRIQKPGSVQTVV
.  ... ..||||. ||||..|.|| . ..  .   .|| .|.....|. | |.||.|||. 
llpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtle

subfamily_Sponge-PTP10_pd Subfamily Sponge-PTP10 810-895 6.6e-31 102.3 In-house 1-81 (287) alignment
Range on Protein: 810-895
Range on HMM: 1-81/287.0
LVPVGQFGEFVANGHAKGNEGFRNQFMMLDS-GESDHSVTVGLTSSNKLLNRFANIVVYDDNRIILRpisghkDCPNEYVNACYVDT
|.||..||||||.|||||||||.|||..|.. ......||....|.|| .||...|.|.|..|..|.      .. ..|.||...|.
lipvekfgefvakghakgnegfknqftvleqvtqredevthniasqnkdknRltqilvpdnyrvllk......gehpdyinavfidg

subfamily_Sponge-PTP9_pd Subfamily Sponge-PTP9 899-991 6.9e-31 102.1 In-house 188-280 (301) alignment
Range on Protein: 899-991
Range on HMM: 188-280/301.0
QSVTQFQITNWGSTGEVKNPQTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVV
..|.|.|.|.|   | |..|.|.|......  .|.| |   .||||||||.|| ..|.   ..  || |||.||||| |. | .||| |.|  
wdvlqlqvtdWpqdGvvreprtvLqviddvihrqqkigggpvvVHCSdtVsrsGvYcsvsiglEQckaegVVdvfqvtkavrrskpgaVtTLe

0039614 (Phosphotyrosine protein) phosphatases II 818-998 2.7e-29 98.0 In-house 21-283 (297) alignment
Range on Protein: 818-998
Range on HMM: 21-283/297.0
EFVANGHAKGNEGFRNQFMMLDSGESDhsVTVGLTSSNKLLNRFANIVVYDDNRIILRPISGHkDCPNEYVNACYVDTGAK-------------------
 ..   .|... .....|..| |   |   ...|   || .||. .|. ||..|..| |. |. | .. |.|| |||.  .                   
lllllekansktllllefeellslkpd..ysiallpenkdknrykdilpydhsrvklkpedgv.dldsdYinAsyvdgydlltrkfIatqgPlpetvedF

-----------------------------------------------------------------QSVTQFQITNWGSTGEVKNPQTILMIMEEMYRTQR
                                                                   ||.|| |.|   |   .....| ..|.. . ..
wrmvweqgvtvivmLtklvelgrkcaqywpeeggtygdftvtllkvehldgytvrtlevtnngesrtvthfqytgwpdhgvppslellleflelvreala

KR-GNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVVSINYSCY
.  ... ..||||. |||...|.|| . .. ...|| .||....|  | |.||.|||   . . ..
elpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflyd

0043336 (Phosphotyrosine protein) phosphatases II 812-997 2.6e-28 94.7 In-house 3-270 (278) alignment
Range on Protein: 812-997
Range on HMM: 3-270/278.0
PVGQFGEFVANGHAKGNEGFRNQFMMLDSGESdHSVTVGLTSSNKLLNRFANIVVYDDNRIILRPISGHKDcpNEYVNACYV------------------
.| .. ..... ..... .....|  |.|     . ...|   || .||. .|. || .|..| ...|. |  . |.|| ||                  
svkdllkallelllnlktllllefeellsfkl.dtysiallpenkdknrykdilpydhsrvklsllggdld..sdYinAsyvdgynvprkfiatqgPlpe

--------------------------------------------------------------------DTGAKQSVTQFQITNWGSTGEVKNPQTILMIM
                                                                     .| .. ||... ..|   |   .....| ..
tvedFwrmvwelgvttivmLtelvelgrvkcaqYwpggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldfl

EEMYRTQRkRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVVSINYSC
... . ..   |. ..||||. |||...|.|. . ..  ..|| .|.....|  | |.||.|||   . . .
kavreale.dsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrfly

subfamily_Sponge-PTP8_pd Subfamily Sponge-PTP8 898-990 1.3e-26 88.5 In-house 177-269 (305) alignment
Range on Protein: 898-990
Range on HMM: 177-269/305.0
KQSVTQFQITNWGSTGEVKNPQTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTV
...|.|.|.|.|   | .. . ..| ..... ..|.|  .....||||..|||. .|.|    ....|.|.|.|||.|||  | .... ||| 
srtvlqyqltdWPdhGvpqfatsllslikrvqkdqkkdkgvpllVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkmvqtl

0042113 (Phosphotyrosine protein) phosphatases II 851-993 1.4e-25 85.5 In-house 5-232 (245) alignment
Range on Protein: 851-993
Range on HMM: 5-232/245.0
LTSSNKLLNRFANIVVYDDNRIILRPISGHKDCPneYVNACYV---------------------------------------------------------
|   || .||. .|. ||..|..| |..|. |..  |.||.||                                                         
llpenkdknrysdilpydhtrvklspdggdldsd..yinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywplge

------------------------------DTGAKQSVTQFQITNWGSTGEVKNPQTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINK
                               .. .. |.... ..|   |.  .....| ..|.. . ... .|. ..||||. |||...|.|| . .. 
sltygdftvtllseehlddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleq

CKTEGVIDVFQVLKSQRIQKPGSVQTVVSI
 ..|. .......|  | |.||.|||   .
lekelgvsleeavkelrsqRpgavqtpsqy

0045098 (Phosphotyrosine protein) phosphatases II 840-994 3.7e-24 81.0 In-house 18-262 (278) alignment
Range on Protein: 840-994
Range on HMM: 18-262/278.0
SGESDHSVTVGLTSSNKLLNRFANIVVYDDNRIIlrpisghkdcpnEYVNACYV----------------------------------------------
.  .  ..|..|  .|. .||. .|. || .|..            .|.|| |.                                              
llgipseitpalylgnldknRykdilpydhsrVk............dYINAsyidgypkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrek

-------------------------------------------DTGAKQSVTQFQITNWGSTGEVKNP--QTILMIMEEMYRTQR------------KRG
                                            .. .  ||......|   |   .|  . .| ..|.. . ..              .
caqywpeggsltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllssllllds

NTSIVVHCSDTVGRSAMFCAAATTINKCktEGVIDVFQVLKSQRIQKPG-SVQTVVSIN
.. ..||||  |||.....|| . .  .  ||..|.....|  | |.|| .||.   ..
ggpvlVHCsaGvgRtGtlvaaylmlell..eggvdlleavkelrsqRpglavqnleqyr

subfamily_Urchin-PTP-2_pd Subfamily Urchin-PTP-2 813-991 1.1e-23 78.2 In-house 8-181 (440) alignment
Range on Protein: 813-991
Range on HMM: 8-181/440.0
VGQFGEFVANGhaKGNEGFRNQFMMLDSGESDHSVTVGLTsSNKLLNRFANIVVYDDNRIILRPISGHKDcpNEYVNACYVDTGAKQSVTQFQITNWGST
| .| ..| |   .    | ... .| || |. |   .|  .||. ||. ||..|| .|..|  . |  |  ..|.|| |..    ... |..   |   
vadfadyvqnn..rrsrafedewsllpsglsqpsdiaslp.nnkvknryrnilaydhsrvmleevkgvpd..sdyinasyingiesrtlkqyhyqgwpdk

GEVKNPQTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVV
|  |    .| .....  .| | ||  ..||||  .||...  |  . . ..|    ||.| ...| | ..|  |||  
gvpkfagpvlkmiqdvnesqekagngpllvhcsagagrtgviiavdsilreakrsdqidifsfinsmrnnrpqmvqtpe

0040439 (Phosphotyrosine protein) phosphatases II 847-991 2.3e-23 78.5 In-house 3-233 (249) alignment
Range on Protein: 847-991
Range on HMM: 3-233/249.0
VTVGLTSSNKLLNRFANIVVYDDNRIILRPISGhkDCPNEYVNACYVD----------------------------------------------------
..|.|   || .||. .|. || .|..| ...|    .. |.|| |.|                                                    
ysvallpenkdknrypdilpydhsrvklsilpg..lflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqyw

-----------------------------------TGAKQSVTQFQITNWGSTGEVKNPQTILMIMEEMYRTQRKR-GNTSIVVHCSDTVGRSAMFCAAA
                                   .| .  |...|.|.|  .|  ......| ..|..   ...   .. ..||||. |||...|.|| 
plggsleygdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaay

TTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVV
. ..  ..|. .|.....|  | |.||.||.  
lmleqlekelgvdleeavkllrsqRpgavqnpe

subfamily_Anemone-PTP-2_pd Subfamily Anemone-PTP-2 897-991 6.3e-23 76.5 In-house 183-277 (298) alignment
Range on Protein: 897-991
Range on HMM: 183-277/298.0
AKQSVTQFQITNWGSTGEVKNPQTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVV
 ...| |.. |.| . |. .| ...| ..... ..|.. ||....|.||. ||||  |.|  . ... |.| |.|||||.|  |...||.|||  
kerevrqlhftsWpdkgvpenatsvldllrkvrasqqqagnkpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqtee

subfamily_PTPRD_pd Subfamily PTPRD 898-989 3.7e-21 70.4 In-house 176-266 (564) alignment
Range on Protein: 898-989
Range on HMM: 176-266/564.0
KQSVTQFQITNWGSTGEVKNPQTILMIMEEMYRTQrKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQT
.. |.||. |.| ..|  ......| ..... ... ....  ||||||  |||. .|..    ... |.|...|..|..|  | |..  |||
sreVrqFhFtsWPdhgvpesatslLdlirkvraln.epdagPivVhCSaGVGRTGtfividamlerikeektvDiyqyvkalrkqRnamVqt

subfamily_Sponge-PTP5_pd Subfamily Sponge-PTP5 901-990 6.1e-21 69.5 In-house 164-252 (283) alignment
Range on Protein: 901-990
Range on HMM: 164-252/283.0
VTQFQITNWGSTGEVKnPQTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTV
.. .|. .| . ||   .   |. .. .   |..  .. |||||| ..||.|.|.||...... .|| |.|||.|.|  | |... ||| 
lahyqvidWleygeqa.iinslvkfnkvislqteskkgPivvhCstgiGrtavfiaasasvkdaltesvvdvfavvkimreqrmmavqtl

Y_phosphatase Protein-tyrosine phosphatase 898-990 7.9e-21 69.9 Pfam-A 132-223 (235) alignment
Range on Protein: 898-990
Range on HMM: 132-223/235.0
KQSVTQFQITNWGSTGEVKNPQTILMIMEEMYRTQrKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTV
|..|.|...|||   |  ..|. .| ..... ... .  ....|||||. |||...|.|. . ......|. .||.|..|. | |.||.||..
krevkqlhytnWpdhgvpespkslldlirkveksk.eaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmvqsl

Y_phosphatase Protein-tyrosine phosphatase 898-990 7.9e-21 69.9 In-house 132-223 (235) alignment
Range on Protein: 898-990
Range on HMM: 132-223/235.0
KQSVTQFQITNWGSTGEVKNPQTILMIMEEMYRTQrKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTV
|..|.|...|||   |  ..|. .| ..... ... .  ....|||||. |||...|.|. . ......|. .||.|..|. | |.||.||..
krevkqlhytnWpdhgvpespkslldlirkveksk.eaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmvqsl

subfamily_Anemone-PTP-6_pd Subfamily Anemone-PTP-6 898-989 2.4e-20 67.9 In-house 174-265 (318) alignment
Range on Protein: 898-989
Range on HMM: 174-265/318.0
KQSVTQFQITNWGSTGEVKNPQTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQT
.. | |...|.|  .|  ... ..| .. .  ..|.| |.. ||||||  |||  .|.|  . ... | |...||||. |  | |..  |||
srqvrqyhytsWpdegvpesgaslldlvrqvskaqqksgagpivvhCsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqt

subfamily_Nvec-PTP-2_pd Subfamily Nvec-PTP-2 898-991 3.3e-20 67.4 In-house 136-229 (250) alignment
Range on Protein: 898-991
Range on HMM: 136-229/250.0
KQSVTQFQITNWGSTGEVKNPQTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVV
.. | |.. ..|   |  .. ...| ..... ..|.. ||. ..|.||  ||||  |.|  . ... |.| |.|||.|.|  |...|..|..  
erivrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidavlerlkkekvvdvfkvikvlrkdrphavesle

subfamily_Anemone-PTP-5_pd Subfamily Anemone-PTP-5 899-990 2e-19 64.8 In-house 178-269 (319) alignment
Range on Protein: 899-990
Range on HMM: 178-269/319.0
QSVTQFQITNWGSTGEVKNPQTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTV
 .|..|| |.|   .  .. ...| ..... ....|  .  ||||||. |||   |..   .... | |||.|||.. .  |.|..  ||. 
RevkhfqyteWpdhdvPekatslldllkrirksrektqsgPivvhCsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrp

subfamily_PTPRA_pd Subfamily PTPRA 898-994 4.8e-19 63.4 In-house 190-285 (330) alignment
Range on Protein: 898-994
Range on HMM: 190-285/330.0
KQSVTQFQITNWGSTGEVKNPQTILMIMEEMYRTQRKRGNtSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVVSIN
.. |.||  | |   |   .|. .| ..... ..... .. .||||||  |||.  |..  . ... |.|...|||...|. | |.|  |||    .
srlvrqfhftswPdvGvPfepiGmlkllkkvkklnqqsag.pivvhcsaGvGrtGtfivldavlervkaerkvdvfefvkrlrlqrpqmvqtdeqye

0037934 (Phosphotyrosine protein) phosphatases II 849-993 8.4e-19 63.5 In-house 4-231 (243) alignment
Range on Protein: 849-993
Range on HMM: 4-231/243.0
VGLTSSNKLLNRFANIVVYDDNRIILrpisghKDcpNEYVNACYVD------------------------------------------------------
..|   |.  ||. .|. ||..|..|      ..  . |.|| ...                                                      
iallpenlsknrysdilpydhsrvkl......eg..sdyinanliyvtprliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywp

---------------------------------TGAKQSVTQFQITNWGSTGEVKNPQTILMIMEEMYRTQRK-------RGNTSIVVHCSDTVGRSAMF
                                 .. .. |.... ..|   |   .|. .| ...|..  ...        ..  ..||||  |||....
gevtygdftvtllseehlddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtl

CAAATTINKCkteGvIDVFQVLKSQRIQKPG-SVQTVVSI
.|| . . ..   | .|.....|  | |.|| .|||   .
iaaylmllll...g.vdleeavkllreqRpgkavqtpsqy

DSPc_SM00195 898-990 1.8e-18 62.2 In-house 157-248 (263) alignment
Range on Protein: 898-990
Range on HMM: 157-248/263.0
KQSVTQFQITNWGSTGEVKNPQTILMIMEEMYRTQRKRgNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTV
...|||.|..||   |  .... .| ...... ....  .. ||||||. |||...|... . ..|...|  .|.|...|. | |.||.||| 
trkvtqyqyknWpdhgvpdstksvlellravkksksts.sgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtl

PTPc_SM00194 898-990 1.8e-18 62.2 In-house 157-248 (263) alignment
Range on Protein: 898-990
Range on HMM: 157-248/263.0
KQSVTQFQITNWGSTGEVKNPQTILMIMEEMYRTQRKRgNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTV
...|||.|..||   |  .... .| ...... ....  .. ||||||. |||...|... . ..|...|  .|.|...|. | |.||.||| 
trkvtqyqyknWpdhgvpdstksvlellravkksksts.sgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtl

PTPc_DSPc_SM00012 901-994 2.5e-18 61.6 In-house 2-97 (105) alignment
Range on Protein: 901-994
Range on HMM: 2-97/105.0
VTQFQITNWGSTGEVKNPQTILMIMEEMYRTQRKRG-NTSIVVHCSDTVGRSAMFCAAATTINKCKTE-GVIDVFQVLKSQRIQKPGSVQTVVSIN
|.....|.|  .|  .... || ..... . ..|.. ....|||||. |||...|.|... ......| . .|.||..|. | |.||.|||     
vkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqyl

I-set Immunoglobulin I-set domain 703-789 1.2e-15 49.1 Pfam-A 1-90 (90) alignment
Range on Protein: 703-789
Range on HMM: 1-90/90.0
PVIEEFPNDVTSEEGCQVHFKVKFKGTPTPFFNWYHNGEPVTDDYAHELRGDG---SLLLVSVEEKHKGTYRFVANNEAGTVSQQVVLTV
|.... ..||. .|| .| .... .|.|.| ..|...|.... .  .... ..   .| . .||.. .|.|. .|.|.||...... |.|
pkftqklkdvevseGesvelectveGepepsvsWakdgselkssqrvkvtveeaeytLtIsnvevsDeGkYtckatnsagkaeakaeLkV

subfamily_Ptp69D_pd Subfamily Ptp69D 896-989 2.5e-15 51.4 In-house 179-271 (307) alignment
Range on Protein: 896-989
Range on HMM: 179-271/307.0
GAKQSVTQFQITNWGSTGEVKNPQTILMIMEEMYRTQRKRgNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQT
 ... |.|.. |.|  .   . ....| ..|...  ...  .. ||||||  ||||..| | .  ....|.|  .|.|.. |  | |..  || 
edsrkvvqyhytgWkDskvPevargllklieqvrelykln.rsPivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnllvqs

subfamily_PTPRK_pd Subfamily PTPRK 898-990 3.3e-15 50.7 In-house 172-263 (314) alignment
Range on Protein: 898-990
Range on HMM: 172-263/314.0
KQSVTQFQITNWGSTGEVKNPQTILMIMEEMYRTQRKrGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTV
.. | ||| ..| . .  .. ...| .. ..  .| . ..  ||||||   ||. .|.| .. ..  ..|||.|||.. |. | .|.  |.| 
irevrqfqflgWpdhdvPvsatgllklvrrvkksqee.eaGrivvhCsaGaGrtGtfiaidivldmieregvvdvfnavktlrsrkvnmvete

subfamily_Urchin-PTPRA_pd Subfamily Urchin-PTPRA 898-995 3.7e-15 51.0 In-house 184-282 (319) alignment
Range on Protein: 898-995
Range on HMM: 184-282/319.0
KQSVTQFQITNWGSTGEVKNPQTILMIMEE-MYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVVSINY
....||| .  |   |  . |  ......   . |........||||||  |||. .. .  . ... | |  .||.....  | |..  || .|   .
irkitqfhflGwpdvGvpdypsdlmrlvkkvrhltskenhranivvhcsaGvGrtGvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykf

subfamily_Urchin-PTP-1_pd Subfamily Urchin-PTP-1 898-990 4e-15 50.5 In-house 172-263 (315) alignment
Range on Protein: 898-990
Range on HMM: 172-263/315.0
KQSVTQFQITNWGSTGEVKNPQTILMIMEEMYRTqRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTV
.. ||||| |.|   |  |.  ..| .. |.    ... . |..||||  |||. .....   ... | . ..|||...|  | ..|  ||| 
srtvtqfqftewPdkGvdkqtssllklikevkad.ngkkefsllvhcsaGvGrtGvvisidevvaqikrtrsvdvfnfvknlrakrpylvqte

subfamily_Urchin-PTP-8_pd Subfamily Urchin-PTP-8 898-995 4.2e-15 51.0 In-house 148-246 (284) alignment
Range on Protein: 898-995
Range on HMM: 148-246/284.0
KQSVTQFQITNWGSTGEVKNPQTILMIMEE-MYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVVSINY
.....|| .  |   |  . |  ......   . |........||||||  |||. .. .  . ... | |  .||.....  | |..  || .|   .
irkirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrtgvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykf

subfamily_Urchin-PTP-6_pd Subfamily Urchin-PTP-6 899-990 5.6e-15 49.4 In-house 172-262 (515) alignment
Range on Protein: 899-990
Range on HMM: 172-262/515.0
QSVTQFQITNWGSTGEVKNPQTILMIMEEMyRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTV
. ||||. |.|   |  |. ...| .. |. .... . . ....|||  |||  .....   . . ||  ..|||....  | ..|  ||| 
rtvtqfhfteWPdkGvpkhtssllklikev.kadhgqythpliihcsaGvGrtGvvisidsvvahakttrmvdvfnfvtnirqkrpylvqtq

subfamily_Sponge-PTP1_pd Subfamily Sponge-PTP1 921-991 5.9e-15 50.0 In-house 176-246 (267) alignment
Range on Protein: 921-991
Range on HMM: 176-246/267.0
ILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVV
.  ..  . . | . ||  .||.||| ||||  |  . . ... ||||| |.|. |.  | |..| |.|  
lkplfgilaknqlengnrPlvvacsdGvGrsGtflvidsqleraktegvsdifdflrkirsqriglvdtke

subfamily_Urchin-PTP-3_pd Subfamily Urchin-PTP-3 894-990 1.2e-14 49.2 In-house 173-274 (325) alignment
Range on Protein: 894-990
Range on HMM: 173-274/325.0
DTGAKQSVTQFQITNWGSTGEVKNPQTILMIMEEMYR---TQ--RKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQ
. |  .|| |||.  |   |  | | |.. |.. .     .     .. | |.||||. |||. .| .  . ..|  .|  .|.|...|  | ..|  |.
kkGetrsvkqfqlqswddmGvqkrpatlisilqlvkavservtantkastpilvhcsaGvGrtGvfislysalakvieesrvdifgfvkklrkdrpsmve

TV
||
tv

subfamily_Choan-PTP-1_pd Subfamily Choan-PTP-1 896-995 1.3e-14 49.0 In-house 167-267 (281) alignment
Range on Protein: 896-995
Range on HMM: 167-267/281.0
GAKQSVTQFQITNWGSTGEVKNPQTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTE-GVIDVFQVLKSQRIQKPGSVQTVVSIN
| ...|.|.. |.|  .|  .... .|   .|......|. ....|.|||  |||.  . |  . ......|   .|| .|... | ..   |||||  .
getreveqlaytaWPdhGvPattkellefrkevlkltekktkaplvihCsaGvGrtGtyialDrlvkaveaeleeldvkavvaelrkernlmvqtvvqye

Y
.
f

subfamily_Urchin-PTP-5_pd Subfamily Urchin-PTP-5 897-990 3.1e-14 47.8 In-house 175-270 (297) alignment
Range on Protein: 897-990
Range on HMM: 175-270/297.0
AKQSVTQFQITNWGSTGEVK--NPQTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTV
|.. | |.| ..| .  . .  . ...| ...|.  .  .. .. ..|||.  ||| .....    . . | |  .|.|...|  | ..|  ||| 
arrvvkqyqfveWPdkaverkdsassllklisevrkdfsqnaegPllvhclaGvGrtgvlltidsvvaeakrekevdifglvkklrqerpylvqtk

subfamily_Sponge-PTP9_pd Subfamily Sponge-PTP9 826-896 4.1e-14 47.0 In-house 12-81 (301) alignment
Range on Protein: 826-896
Range on HMM: 12-81/301.0
KGNEGFRNQFMMLDSGEsDHSVTVGLTSSNKLLNRFANIVVYDDNRIILRPISGHKDCPNEYVNACYVDTG
| ...| .|.  |..|| |.| ||||...|| |||| ||.|||||||||.| .  . | .||.|| |.|  
khsnkfeeqykelkege.dksctvglseenkalnrfknitvyddnriilkpkpnldlcqreyinasyidgy

0036282 (Phosphotyrosine protein) phosphatases II 895-989 5.3e-14 47.8 In-house 63-155 (174) alignment
Range on Protein: 895-989
Range on HMM: 63-155/174.0
TGAKQSVTQFQITNWGSTGEVKNPQtILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKtEGVIDVFQVLKSQRIQKPGSVQT
.  .... |.. ..|   |.   .. .| ....... . . ..  ..||||  |||.....||   .   . |...|........| |.||.|||
edlerlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqt

subfamily_PTPN23_pd Subfamily PTPN23 896-996 5.5e-14 46.7 In-house 168-272 (288) alignment
Range on Protein: 896-996
Range on HMM: 168-272/288.0
GAKQSVTQFQITNWGSTGEVKNPQTILMIMEEM---YRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCK-TEGVIDVFQVLKSQRIQKPGSVQTVV
 |..||.  |.|.| . |  . |.|.| ...|.   |...... .| .|||||  |||. .|.   . ... .  .|..|. ||..  | |.  .||.. 
davksvshlqltsWpelGvPasPetllqfldevesayeavqrksktPlvvhCsaGvgRtgvfalvyaavrelekgnglldiiqvvsrlreqRrfmvqeke

SINYS
 .. |
qlkfs

subfamily_Urchin-PTP-7_pd Subfamily Urchin-PTP-7 899-991 5.5e-14 46.8 In-house 175-266 (315) alignment
Range on Protein: 899-991
Range on HMM: 175-266/315.0
QSVTQFQITNWGsTGEVKNPQTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVV
. | |...| |  . .| .  . || .    .  ..   ..||||||. |||.  |..  . ... ..| .|||.....  | .. . ||.. 
revvqlhytswp.dmgvpkytiplmnlirtvkqhhtnsvgaivvhcsaGvGrtGtfitldavldqaeaenaidvynfitgvrqnrikmvqvae

subfamily_PTPN12_pd Subfamily PTPN12 896-989 6e-14 46.6 In-house 167-262 (290) alignment
Range on Protein: 896-989
Range on HMM: 167-262/290.0
GAKQSVTQFQITNWGSTGEVKNPQTILMIMEEMyRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGV---IDVFQVLKSQRIQKPGSVQT
.....|.||. |.|   |  ......| ..|.. |. ... .. .|||||  |||    .|   . .  |.| .   .|||... . | |..  |||
kesrkvyqfhYtaWPDhgvPssaksllelielv.relqesedaPlvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqt

subfamily_PTPRD_pd Subfamily PTPRD 810-895 7e-14 46.4 In-house 4-86 (564) alignment
Range on Protein: 810-895
Range on HMM: 4-86/564.0
LVPVGQFGEFVANGHAKGNEGFRNQFMMLDSGeSDHSVTVGLTSSNKLLNRFANIVVYDDNRIILRPISGHKDCpnEYVNACYVDT
 .|| .. |.||. .|...  | ...  ...| . .....   . ||  ||.|||| || .|..|... |....  .|.|| ..|.
pipvaelkehvaklkansdlkfeeeykkieeg.qqftweaankpaNkaKNRyanivaYdhsRVvLskvegdegs..DYINAsfidg

subfamily_Urchin-PTPRB-like_pd Subfamily Urchin-PTPRB-like 897-993 7e-14 46.5 In-house 173-268 (288) alignment
Range on Protein: 897-993
Range on HMM: 173-268/288.0
AKQSVTQFQITNWGSTGEVKNPQTILMIMEEMYRTQRKRgNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVVSI
 .  .||.| . |  .|  .. . .| ... .  .. .     |.||||. |||.  | |. . |.. ..| .|||. ...  | |..  |||.   
teleitqyqylaWpdhgvPeskapllellrqvkvanqad.tgpiivhCsaGvGrtgtFialdalidaveeedyiDvagtvaklRkqRallvqtlkqY

subfamily_PTPRB_pd Subfamily PTPRB 897-991 9.8e-14 46.1 In-house 177-272 (293) alignment
Range on Protein: 897-991
Range on HMM: 177-272/293.0
AKQSVTQFQITNWGSTGEVKNPQTILMIMEEMYRTQ-RKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVV
....|.|.. | |   |  ....|.| ..... ... ..  .. ||||||  |||.  | |  . ... ..| ..|.| .. . | ..   |||. 
eerkvrqyhftsWpdhgvPektktlldfvrtvreaiektaskrPivvhCsaGvGRtGtfialdrllqaieeedyvdifgivaelReeRnllvqtek

fn3 Fibronectin type III domain 400-471 1.3e-13 44.0 Pfam-A 11-84 (85) alignment
Range on Protein: 400-471
Range on HMM: 11-84/85.0
KNPDAINIVWNPPTIPNGIIAVYEIRYRESTSTG-PYNITNTTNT-YYSIVGLIPNTSYTIGVRAYTSIGPGEW
 ... ... |.||. ..| |  ||..|||..... . ..|.. .|  . . || |.|.|.. |.|..  | |..
vtstsltlsWsppkdgggpitgYeveyrekgggeewkeftvprtttsvtltgLkpgteYefrVqavngagegpe

subfamily_PTPN5_RR_pd Subfamily PTPN5_RR 898-990 1.8e-13 45.2 In-house 160-254 (274) alignment
Range on Protein: 898-990
Range on HMM: 160-254/274.0
KQSVTQFQITNWGSTGEVKNPQTILMIMEEMYRTQRKRGNT--SIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTV
..||. .  |.|  .   ....|.| ...|. ...... .   ..|||||  .||  .| |.  .... . |.|.||...    |... | ||| 
ersvkhywytdWPdhksPddantlldlvleveesreeenaklapvvvhCsaGiGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqts

fn3 Fibronectin type III domain 297-377 3.5e-13 42.7 Pfam-A 5-83 (85) alignment
Range on Protein: 297-377
Range on HMM: 5-83/85.0
DIIFSSVESVSMTVSWDEVPcnGRNGPITGYYLTYTNITSNTSCIVNITGGDNRMYNLTGLIPYTNYTVSIIPYNYNMNGP
.. .|.| | |.|.||.. .   ..|||||| ..| . ...  .    . .. . ..|||| |.|.|....  .| . .||
nlsvsevtstsltlsWsppk..dgggpitgYeveyrekgggeewkeftvprtttsvtltgLkpgteYefrVqavngagegp

subfamily_PTPRG_pd Subfamily PTPRG 898-990 4.3e-13 43.3 In-house 182-273 (563) alignment
Range on Protein: 898-990
Range on HMM: 182-273/563.0
KQSVTQFQITNWGSTGEVKNPQTILMIMEEMYRTQRKrGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTV
.. |.|.. |.|  .|  . .   |. ..   .....     ||||||  |||. ....  | ... ..| ...||..||  | |..  ||| 
eklvrqyhytkWPdhgvPehslpvLifvkkssaanka.eaGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvqte

0041856 (Phosphotyrosine protein) phosphatases II 855-995 9.2e-13 43.6 In-house 1-162 (182) alignment
Range on Protein: 855-995
Range on HMM: 1-162/182.0
NKLLNRFANIVVYDDNRiilrpisghkdcPNEYVNACYVDTGAKQ--------------------------------------------SVTQFQITNWG
|. .||. .|. || .|            .. |.|| ... . ..                                             ..|.. ..| 
nldknrysdilpydhsr............dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlteelywpellerlgiqylylpwp

STGEVKnPQTILMIMEEMYRtqrkrGNTSIVVHCSDTVGRSAMFCAAATTINKckteGvIDVFQVLKSQRIQKPGSVQTVVSINY
  |    ....| ..||...      .  ..||||  |||.....||   . .    | .......|  | ..||.|.|   . .
Dhgvpd.ldelldfieevle.....eggpvlVHCsaGvgRtgtlvaaylmkkl....g.vsleeavklvrsrRpgmvitpnqyff

subfamily_CG7180_pd Subfamily CG7180 900-994 1e-12 42.3 In-house 181-280 (296) alignment
Range on Protein: 900-994
Range on HMM: 181-280/296.0
SVTQFQITNWGSTGEVKNPQTILMIMEEMYRTQRKRG-----NTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVVSIN
 |..||.| | .  .|    . |. . .. |. |..      .  .||..|| ..|| ...|.  .... . |. .|||. .|  |...|. |..|    
ivklfqlteWeledkvPlstnalielrrrvrlwrekvdedpeegPvvvvssdGasRsGvylaidanlelvekeeevdvFeavktlrrsRpqLvenveeYk





subfamily_PTPRG_pd Subfamily PTPRG 811-895 1.2e-12 41.8 In-house 1-86 (563) alignment
Range on Protein: 811-895
Range on HMM: 1-86/563.0
VPVGQFGEFVANGHAKGNEGFRNQFMMLDSGESDH--SVTVGLTSSNKLLNRFANIVVYDDNRIILRPISGHKDCPnEYVNACYVDT
||| .| . ||. ||.|. || ..|  | |   ..   ..     .||  ||  ||| ||  |. |.|..|.|.   .|.|| |.| 
vpvkefakhvaslhadgdigfseefealqsetiskdldaehsqkpenkrKnRylnivaydrsRvklsplpgkkkkl.DYinAnyidG

0043147 (Phosphotyrosine protein) phosphatases II 891-993 2.3e-12 42.5 In-house 55-150 (172) alignment
Range on Protein: 891-993
Range on HMM: 55-150/172.0
CYVDTGAKQSVTQFQITNWGSTGEVkNPQTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTInkckteG-ViDVFQVLKSQRIQKPGSVQT
.|  .. .... |.. ..|   |   ... .| ..| ... . .. .  ..||||  |||.....||   .        . .......  | ..||.||.
lydpellerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml......lgl.sleeavalvrekRpgavqn

VVSI
   .
psqy

subfamily_PTPN6_pd Subfamily PTPN6 897-992 1.1e-11 39.3 In-house 184-285 (306) alignment
Range on Protein: 897-992
Range on HMM: 184-285/306.0
AKQSVTQFQITNWGSTGEVKNPQTILMIMEEMYRTQRKRG---NTSIVVHCSDTVGRSAMFCAAATTINKCKTEGV---IDVFQVLKSQRIQKPGSVQTV
 ...| |.. ..|   |  |.|...|  .|.. | |..     . .||||||. .||   |    . ... ...|.   ||. .. || | |. | ||| 
eerevfqyhfksWPdhgvpkdpgavLdfledvnrkqeeleeaeagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqte

VS
  
qq

subfamily_PTPN13_pd Subfamily PTPN13 894-990 1.2e-11 39.5 In-house 161-255 (273) alignment
Range on Protein: 894-990
Range on HMM: 161-255/273.0
DTGAKQSVTQFQITNWGSTGEVKNPQTILMIMEEMYRTQRkrGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTV
..|. . |.... ..|   |  .... .| .. |. | |.   .. ||||||  .||| .. .  . ..  . .  .|| ..... | |. | ||| 
esgesrevahlnfvkwPdhgvPssaaellqfvaevrrlqt..dagPivvhcsaGiGrsGtlitidvvlglierdkefdvkeivrklreqrqgvvqtk

subfamily_Anemone-PTP-5_pd Subfamily Anemone-PTP-5 811-895 3.9e-11 37.6 In-house 5-86 (319) alignment
Range on Protein: 811-895
Range on HMM: 5-86/319.0
VPVGQFGEFVANGHAKGNEGFRNQFMMLDSGESDhSVTVGLTSSNKLLNRFANIVVYDDNRIILRPISGHKDcpNEYVNACYVDT
..| .. | . . ...|. .....|..|. ...| ...   .  ||  ||. ||. ||  |..| .. | ..   .|.|| ..|.
ievqeLkerlkalastgetllekefkllkeavnd.tfdsaskeenkkknryqnilaydrtrvvlseldgveg..sdyinasfidg

subfamily_Choan-PTP-2_pd Subfamily Choan-PTP-2 895-995 4.2e-11 37.3 In-house 148-255 (270) alignment
Range on Protein: 895-995
Range on HMM: 148-255/270.0
TGAKQSVTQFQITNWGSTGEVKNP------QTILMIMEEMYRTQRKRGN-TSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSV
.| .. .. |. ..|   | ....      . .| ..... |....  . . ..||||. |||. .. |  ....  .... .|| ....  | ...  |
kgeerrlvHfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcsaGvgRtGtlialDiavrlLeetkkvdvlaiieelRkdRmalv

QTVVSINY
|... ...
qhpeqyef

subfamily_Ptp69D_pd Subfamily Ptp69D 818-894 4.9e-11 37.3 In-house 11-85 (307) alignment
Range on Protein: 818-894
Range on HMM: 11-85/307.0
EFVANGHAKGNEGFRNQFMMLDSGESDHSVTVGLTSSNKLLNRFANIVVYDDNRIILRPISGHKDCpnEYVNACYVD
| . . . . ..|. . . .| . |.|.| .|.    |.| ||. .|. .|..|..|..| |..|   .|.|| .. 
ealksrkrdtdfglakeyekLeareidkstkvsekkenalknRyedikafDktRvkLkkingkeds..dYinasfik

0048076 (Phosphotyrosine protein) phosphatases II 888-991 5.5e-11 37.8 In-house 34-130 (145) alignment
Range on Protein: 888-991
Range on HMM: 34-130/145.0
VNACYVDTGAKQSVTQFQITNWGSTGEVKNPQTILMIMEEMYRTQRKrgNTSIVVHCSDTVGRSAMFCAAATTINkcktEGvIDVFQVLKSQRIQKPGSV
.| ..  .. .. ..|.. ..|   |.   ....| ..| . . ...  .  ..||||  |||.....||   .     .| ......|.  | | ||.|
lnltselellerlgiqylylpwpDhgvpdllellleflefieealke..ggpvlVHCsaGvgRtgtlvaaylmll....lg.vsleealelvrsqrpgav

QTVV
... 
pnpg

subfamily_Urchin-PTPRB-like_pd Subfamily Urchin-PTPRB-like 819-899 1.3e-10 35.8 In-house 11-89 (288) alignment
Range on Protein: 819-899
Range on HMM: 11-89/288.0
FVANGHAKGNEGFRNQFMMLDSGESDHSVTVGLTSSNKLLNRFANIVVYDDNRIILRPISGHKDcpNEYVNACYVDTGAKQ
 ||. .|....|| ...  | . |...|||.|  . |.  ||. ||. || .|. |.     ..  ..|.|| |.|   |.
kvakksarnrtgfseeynsLaalektksvtagrlavnakknRyrnilpyDekrvklkkleeeag..aDYinasyidgekkk

0051429 (Phosphotyrosine protein) phosphatases II 876-991 1.7e-10 36.6 In-house 76-212 (272) alignment
Range on Protein: 876-991
Range on HMM: 76-212/272.0
PISGHKDCPNEYVN---------------------ACYVDTGAKQSVTQFQITNWGSTGEVKNPqtILMIMEEMYRtqrkrgNTSIVVHCSDTVGRSAMF
|| .. . . .| .                       ....|.   |.... |.|   |  ...  .| ..|.. .      .  ..||||  ..|....
pilddsaptilygalrvtllseellldyilrellltlllsagearevmhlhytdwpdhgvpqea..llellellld......ggpvlvHCsaGkdRTGtv

CAAATTINKCKTEGVID--------VFQVLKSQRIQKPGSVQTVV
.|.   .     | ..|        ......  | | ||.|||  
vallllllgvsletivddYlltnlyleeaveelraqrpgavqtee

subfamily_Anemone-PTP-6_pd Subfamily Anemone-PTP-6 811-897 1.8e-10 35.4 In-house 2-86 (318) alignment
Range on Protein: 811-897
Range on HMM: 2-86/318.0
VPVGQFGEFVANGHAKGNEGFRNQFMMLDSGESDHSVTVGLTSSNKLLNRFANIVVYDDNRIILRPISGHKDcpNEYVNACYVDTGA
..| .. . |.. ...|.  . ... .|.  |.  . .  |.. ||  ||.|||. ||. |. |....|...   .|.|| |.|   
isvedleshvrrlresGelllseeyerlsrseetvtslkslepvnkaknryanilaydhtrvkLqmlegeeg..sDyinanyidGyr

subfamily_Sponge-PTP8_pd Subfamily Sponge-PTP8 811-895 2.1e-10 35.2 In-house 4-84 (305) alignment
Range on Protein: 811-895
Range on HMM: 4-84/305.0
VPVGQFGEFVANGHAKGNEGFRNQFMMLDSGesDHSVTVGLTSSNKLLNRFANIVVYDDNRIILRPISGHKdcPNEYVNACYVDT
. . .. ... . ... ..|. .|. .| .   ..|. || .. ||  ||...|...||.||||.. . ..   ..|.||.|||.
ialddlaayikearvysdkgleaqykslyee..eesidvgkkeankaknrlkeitlldddriiltekesld..dsdyinasyvdg

subfamily_Urchin-PTP-4_pd Subfamily Urchin-PTP-4 897-990 4.3e-10 33.5 In-house 276-371 (392) alignment
Range on Protein: 897-990
Range on HMM: 276-371/392.0
AKQSVTQFQITNWGSTGEVKNP--QTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTV
|  .|||.|.  |   |  ...  ...| ..  .  .  .. . ||.|||    ||. .||.|   | .      .|.|| .|  | ..  .||| 
ashtvtqyqfhgwpkhgsdqqsgarsllkliravkgstnskkefsilvhclsgagrtgvfctameciaqiaegdsvdifqtvkilradrmqfvqte

subfamily_PTPN3_pd Subfamily PTPN3 897-997 4.6e-10 33.9 In-house 169-268 (280) alignment
Range on Protein: 897-997
Range on HMM: 169-268/280.0
AKQSVTQFQITNWGSTGEVKNPQTILMIMEEMyRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVVSINYS
 .....|.| ..|   |  .... .| ..|.. |..|.  .. .|||||  .||. .. .  |.. .  ..  . . ....  | |.   |||.   .. 
eerkilqlqylaWpdhgvPddsadflefverv.rklrsgkeePvvvhCsaGigrtGvlilletalalieaaepvypldivrtmrdqramlvqtasqykfv

C
|
C

0049260 (Phosphotyrosine protein) phosphatases II 888-994 4.9e-10 34.8 In-house 55-140 (152) alignment
Range on Protein: 888-994
Range on HMM: 55-140/152.0
VnacyvdtgakqsvtQFQITNWGSTGEVKNPQTILMIMEEMYRTqRKRGNTSIVVHCSDTVGRSAMFCAAATTInkckteGVIDVFQVLKSQRIQKPGSV
               |.. ..|   |  ...| .|.... . .  ... .  ..||||  |||.....||   .        ........  | ..||.|
i..............qylhlpwpDhgvpdlsqlllflllfiekl.aldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgav

QTVVSIN
..   . 
pnpgqlr

subfamily_PTPRN_pd Subfamily PTPRN 895-992 4.9e-10 33.6 In-house 183-280 (297) alignment
Range on Protein: 895-992
Range on HMM: 183-280/297.0
TGAKQSVTQFQITNWGSTGEVKNPQTILMIMEEMYRTQRKRGnTSIVVHCSDTVGRSAMFCAAATTINKC-KTEGVIDVFQVLKSQRIQKPGSVQTVVS
|   ..||||    | ..|   .....|     . .. | |  ..||||||| .||. ....    .|.  |    ||.   |.  | |.|| |.|   
tsetrtvtqfhflswpeegvPasaksllefrrkvnksyrGrs.cpivvhcsdGaGrtGvyilidlvlnrllkGvkeidiaatlehlrdqrpglvktkdq

subfamily_PTPRB_pd Subfamily PTPRB 811-894 7.1e-10 33.4 In-house 7-88 (293) alignment
Range on Protein: 811-894
Range on HMM: 7-88/293.0
VPVGQFGEFVANGHAKGNEGFRNQFMMLDSGESDHSVTVGLTSSNKLLNRFANIVVYDDNRIILRPISGHKDcpNEYVNACYVD
. . .| |.|.. .|. . .| ... .| . ..|..|..  .. |.  ||. ||. || .|. | .......  ..|.|| |..
iklekfeehvkkmkadsdlrfseeyeelkavgkdqavkaaelavnraknrytnilpydhsrvkLaalkdesg..sDYinanyip

subfamily_PTPN9_pd Subfamily PTPN9 897-992 7.9e-10 33.2 In-house 171-278 (297) alignment
Range on Protein: 897-992
Range on HMM: 171-278/297.0
AKQSVTQFQITNWGSTGEVKNPQTILMIMEEMYRTQR---------KRG---NTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKP
 ...|| ||.. |   |  .. ...| ..|.. ..|          ..|   .  ||||||  .||.  |..   .... ...|..||....|  | |. 
esrkvthfqflsWPdyGvPssaaslldvlekvrekqalavkelgdewkghpsgPPivvhcsaGiGrtGtfitldiclsrleevgtvdvvetvkllrtqra

GSVQTVVS
 |.||   
fsiqtpeq

0048179 (Phosphotyrosine protein) phosphatases II 895-991 9.3e-10 33.9 In-house 48-132 (144) alignment
Range on Protein: 895-991
Range on HMM: 48-132/144.0
TgakqsVTQFQITNWGSTGEVKNPQTILMIMEEMYRTQRkrGNTSIVVHCSDTVGRSAMFCAAATTInkckTEGvIDVFQVLKSQRIQKPGSVQTVV
.     ..|.. ..|   |    .. .| ..| . . ..   .  ..||||  |||.....||   .    ..| ......|.  | . ||.|..  
e.....giqylhlpwpDhgvpdllellleflefieeale..eggpvlVHCsaGvgRtgtlvaaylmk....klg.lsleealalvrsrrpgavpnpg

subfamily_Anemone-PTP-2_pd Subfamily Anemone-PTP-2 819-896 1.7e-09 32.3 In-house 17-95 (298) alignment
Range on Protein: 819-896
Range on HMM: 17-95/298.0
FVANGHAKGNEGFRNQFMMLDSGES---DHSVTVGLTSSNKLLNRFANIVVYDDNRIILRPISGHKDCpnEYVNACYVDTG
..|  ..|.  |. ..|  |.|..|   ... .|. ...||  ||.|.|. .|  |..|. ... ...  .|.|| .... 
laavkkkkkltgyalefqrlnsvsseieeeekevarkpenkkkNRyadiialdssRvvLekedadees..dYiNAsflhay

0049772 (Phosphotyrosine protein) phosphatases II 843-987 1.8e-09 33.3 In-house 34-263 (314) alignment
Range on Protein: 843-987
Range on HMM: 34-263/314.0
SDHSVTVGLTSSNKLLNRFANIVVYDdNRIILrPISGHKDCPneYVNACYV-------------------------------------------------
......|.    |.  ||. .|. .| || || |  .....   | || ||                                                 
peltilvadlflnrdknryldilpad.nrvil.pglpvsgsd..yinasyvdgflkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivmsrd

-------------------------------------------DTGAKQSVTQFQITNWGStGEVKNPQTILMIMEEMYRTqrkRGNTSIVVHCSDTVGR
                                           .   .. . ..  ...   |..  .. .. ..| . .    . .. ..|||.. .||
evladelsrLdaAlgKtpllildgngneptaadlellkeelydpelferlgikylripvpD.gsaplledfdeflefieea...dkggpvlvHCkaGkgR

SAMFCAAATTINKCKTeGVIDVFQVLKSQRIQKP--GSV
.. |..||  . ...   . .... ....|  .|  |..
tgtfvvaaylmkllgv.sleealedvrlkRpinpnpgfi

subfamily_Choan-PTP-1_pd Subfamily Choan-PTP-1 824-895 2.2e-09 31.8 In-house 10-79 (281) alignment
Range on Protein: 824-895
Range on HMM: 10-79/281.0
HAKGNEGFRNQFMMLDSGESDHSVTVGLTSSNKLLNRFANIVVYDDNRIILRPISGHKdcPNEYVNACYVDT
... |.|| ...  | . . |.. |   .  |.| ||. ||| ||  |. . | . .|   ..|.|| .|..
sqndnaGfieeyeklaaigvdntataskadenvlknrYsnivaYDatrvkvtpneenk..ntDYinanfvpg

subfamily_PTPN1_pd Subfamily PTPN1 895-996 2.7e-09 31.1 In-house 158-263 (290) alignment
Range on Protein: 895-996
Range on HMM: 158-263/290.0
TGAKQSVTQFQITNWGSTGEVKNPQTILMIMEEMYRTQR-KRGNTSIVVHCSDTVGRSAMFCAAATTIN---KCKTEGVIDVFQVLKSQRIQKPGSVQTV
|   .....|  | |   |  . |.. |  . .. ..   ..     |.|||  .|||  || . | .    | .    .|. .||   | .. | .|| 
tqetreilhfhyttwpdfgvpespaaflkflfkvresGslssdvGpavihcsaGiGrsGtfclvdtclvliekkddlssvdikkvllelrkyrlGliqta

VSINYS
  ...|
dqlrfs

subfamily_PTPRA_pd Subfamily PTPRA 809-895 3e-09 31.2 In-house 12-96 (330) alignment
Range on Protein: 809-895
Range on HMM: 12-96/330.0
NLVPVGQFGEFVANGHAKGNEGFRNQFMMLDSGESDHSVTVGLTSSNKLLNRFANIVVYDDNRIILRPISGHKDcpNEYVNACYVDT
  .|| .. | .    |  |. ||..|  | .|. . .. .     ||  ||. ||. || .|.|| ...|...   .|.|| ..| 
fplpvekleeeirirsaddnklfreefnalPagpiqatlelaskeenkeknrvvnilPydfsrvilsvkeGvee..sdyinasfidG

0046846 (Phosphotyrosine protein) phosphatases II 899-991 5.8e-09 31.4 In-house 74-160 (176) alignment
Range on Protein: 899-991
Range on HMM: 74-160/176.0
QSVTQFQITNWGSTGEVKNpQTILMIMEEMYRTQRKRgnTSIVVHCSDTVGRSAMFCAAAttinKCKTEGVIDVFQVLKSQRIQKP-GSVQTVV
.   |.. ..|   |     . .| ..|.... ...     ..||||  .||.....||      ...|  ..|...|.  | |.| |.|||  
klgiqylhlpwpDhgvpdl.elllellefirealkeg..gpvlVHCsaGigRtgtlvaay....llelekglsveealalvreqRplgavqtpe

subfamily_Sponge-PTP3_pd Subfamily Sponge-PTP3 813-899 8.5e-09 29.5 In-house 7-87 (95) alignment
Range on Protein: 813-899
Range on HMM: 7-87/95.0
VGQFGEFVANGHAKGNEGFRNQFMMLDSgESDHSVTVGLTSSNKLLNRFANIVVYDDNRIILrpiSGHKDcpNEYVNACYVDTGAKQ
|  |   | . |.. .. | |.|  .    |  . ||| . .|   ||| ||. ||  |..|   . ..|   .|.|||.||  |..
vsvfhshvlemhsnsdqefdnefksism.tsgapytvgsseanipknrflnifpydatrvvl...ttkrd..sdyinacfvdgyark

0051082 (Phosphotyrosine protein) phosphatases II 899-991 1.4e-08 30.0 In-house 58-140 (151) alignment
Range on Protein: 899-991
Range on HMM: 58-140/151.0
QSVTQFQITNWGSTGEVKNPQTILMIMEEMYRtqrkRGNTSIVVHCSDTVGRSAMFCAAATTINKcktegvIDVFQVLKSQRIQKPGSVQTVV
  |....|..|  .|   .....| ..|.. .     .|  ..||||  .||.....|.   . .      ......|.  |.. ||.||.  
ievlhipildwpdpglplsfdavleflellld....kkngpvlvHCsaGkgRTGtlvalylmllg......vsleealeeyrlkrpgvvqpnq

subfamily_Cele-PTP-7_pd Subfamily Cele-PTP-7 889-995 1.5e-08 28.4 In-house 179-279 (302) alignment
Range on Protein: 889-995
Range on HMM: 179-279/302.0
NACYVDtGAKQSVTQFQITNWGSTGEVKNPQTILMIMEemYRTQRKrgnTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQ
|    .   |..|  .. . |   |  |...| | |.   .    |   ....||||  |||.  . |    |. |... | |. ....  |  . |.||
nekkkk.kvkktvdilafsawpdhGapkeaytaldilk..fcesyk...knvlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavq

TVVSINY
.   . |
deqqliy

DSPc_SM00195 831-896 3.7e-08 28.4 In-house 2-65 (263) alignment
Range on Protein: 831-896
Range on HMM: 2-65/263.0
FRNQFMMLDSGESDHSVTVGLTSSNKLLNRFANIVVYDDNRIILRPISGHkdCPNEYVNACYVDTG
....|  |.. .|....| .  ..||  ||. ||..||..|..| .. ..   ...|.|| |... 
lkeefekleestspketteaekkknksknRyknilpydhtrVklkkeekk..egsdYINAnyikga

PTPc_SM00194 831-896 3.7e-08 28.4 In-house 2-65 (263) alignment
Range on Protein: 831-896
Range on HMM: 2-65/263.0
FRNQFMMLDSGESDHSVTVGLTSSNKLLNRFANIVVYDDNRIILRPISGHkdCPNEYVNACYVDTG
....|  |.. .|....| .  ..||  ||. ||..||..|..| .. ..   ...|.|| |... 
lkeefekleestspketteaekkknksknRyknilpydhtrVklkkeekk..egsdYINAnyikga

subfamily_PTPN14_pd Subfamily PTPN14 892-991 5.8e-08 27.1 In-house 176-283 (300) alignment
Range on Protein: 892-991
Range on HMM: 176-283/300.0
YVDTGAKQSVTQFQITNWGSTGEVKNPQTILMIMEEMYRTQRKRGNT--------SIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQK
.. .. ...|  .| |.|   |  ..... |  .||.   .||  ..         ..||||. |||. .   .   |.  ... .||. .||.  | |.
hlpskeertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseveskeskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLreqr

PGSVQTVV
   |||. 
mllvqtla

subfamily_Nvec-PTP-1_pd Subfamily Nvec-PTP-1 898-990 6e-08 27.1 In-house 135-226 (239) alignment
Range on Protein: 898-990
Range on HMM: 135-226/239.0
KQSVTQFQITNWGSTGEVKNPQTILMIMEEMYRtQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTV
.. | |...| |   |  .   ..| .  .. . .   |    |.|||  |||.  |    . . ..| .  .|.|. .|. | ..|  ||| 
eryvyqyhftvwpdkgvpqyatavlglrrkitk.dslpgarpwvihcsagvgrtgaflvidamlrqakkqktvdifnyvkairedrphmvqts

subfamily_Anemone-PTP-1_pd Subfamily Anemone-PTP-1 898-990 6.1e-08 27.1 In-house 136-227 (239) alignment
Range on Protein: 898-990
Range on HMM: 136-227/239.0
KQSVTQFQITNWGSTGEVKNPQTILMIMEEMYRtQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTV
.. | |...| |   |  .   ..| .  .. . .   |    |.|||  |||.  |    . . ..| .  .|.|. .|. | ..|  ||| 
eryvyqyhftvwpdkgvpqyatavlglrrkitk.dslpgarpwvihcsagvgrtgaflvidamlrqakkqktvdifnyvkairedrphmvqts

subfamily_PTPN6_pd Subfamily PTPN6 822-899 6.2e-08 27.0 In-house 19-95 (306) alignment
Range on Protein: 822-899
Range on HMM: 19-95/306.0
NGHAKGNEGFRNQFMMLDSGESD--HSVTVGLTSSNKLLNRFANIVVYDDNRIILRpisGHKDCPNEYVNACYVDTGAKQ
... ....|| ..|  |.  |.   .| . |   .||  ||. ||. .|..|.||.    ..   ..|.|| |... .|.
eeeslekagfeeefeelqqeeakkllsrkegakpenkeknryknilPfDhtrvilk...epsvpgsdyinanyikkevkg

subfamily_Urchin-PTP-3_pd Subfamily Urchin-PTP-3 815-898 8.7e-08 26.6 In-house 9-89 (325) alignment
Range on Protein: 815-898
Range on HMM: 9-89/325.0
QFGEFVANGHAKGNEGFRNQFMMLDSGESdHSVTVGLTSSNKLLNRFANIVVYDDNRIILRPIsgHKDCPNEYVNACYVDTGAK
.. |.| . .|. ..|| ..| .| | ..  . .|     ||  ||| |.| .| .|..|     ..|   .|.|| |. .  |
nlvehvekkkaqdqdgfahefgllpsddg.iakkvamkpenkaknrfknvvaldksrvvletk..kddpssdyinasylrddkk

subfamily_Urchin-PTP-7_pd Subfamily Urchin-PTP-7 811-895 8.8e-08 26.4 In-house 6-87 (315) alignment
Range on Protein: 811-895
Range on HMM: 6-87/315.0
VPVGQFGEFVANGHAKGNEGFRNQFMMLDSGEsDHSVTVGLTSSNKLLNRFANIVVYDDNRIILrPISgHKDCPNEYVNACYVDT
.|. |.  .||. .|  ..||....  .  |.  | . |   . ||  ||. ||. ||  |. | |.   .|   .|||| ..| 
ipldqlityvaqkkastkngfkqdyesipggq.lhpldvakkienkqknryiniiaydksrvql.pll.endphsdyvnanfidG

subfamily_Choan-PTP-3_pd Subfamily Choan-PTP-3 897-997 9.5e-08 26.2 In-house 166-270 (287) alignment
Range on Protein: 897-997
Range on HMM: 166-270/287.0
AKQSVTQFQITNWgsTGEVKNPQ---TILMIMEE--MYRTQRK-RGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTV
  . | |... .|    .|  |     | ....       .|.  .   .|||..  .||| .. |  . ... .  | .|| .|.   | .. . ||.|
earvvkqldllsw..PdkvlaPtavglirfvldvkqhielardasevGPlvvhddvGiGrsGillatlvlvsrledlGrvdvaavvirlreyraalvqav

VSINYSC
| . ...
vqlrlly

subfamily_Cele-PTP-19_pd Subfamily Cele-PTP-19 898-992 1.3e-07 25.7 In-house 180-269 (301) alignment
Range on Protein: 898-992
Range on HMM: 180-269/301.0
KQSVTQFQITNWGSTGEVKNPQTILMIMEeMYrtqrKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVVS
 ..|| .| ..|   |  |    .  .|| .     |. .  ||||||. .|||  | ..    .. ...  |.. . ||  | ..  .|||.  
trtvthyqysewtdrgvPkshaelfdlme.lv....kksekPivvhcsaGiGrsvafigteylareveadptieltealkhlrehrwngvqtnsq

fn3 Fibronectin type III domain 106-178 2.2e-07 24.1 Pfam-A 2-77 (85) alignment
Range on Protein: 106-178
Range on HMM: 2-77/85.0
TPTDLNATRLstDLSRVRLSWSTV----SGATGYEVYYQLSSSTPVSAGTTAFKST-SMDVSGLFRGSTYTFYVVSYG
 |..|...      . ..||||      .  ||||| |. .... ..   |. ..| |. ..||  |..|.| | .. 
aPenlsvsev..tstsltlsWsppkdgggpitgYeveyrekgggeewkeftvprtttsvtltgLkpgteYefrVqavn

Ig_3 Immunoglobulin domain 702-776 2.7e-07 22.7 Pfam-A 2-75 (75) alignment
Range on Protein: 702-776
Range on HMM: 2-75/75.0
PPVIEEFPNDVTSEEGcqVHFKVKFKGTP-TPFFNWYhNGEPVTDDYAHELRGDGSLLLVS-VEEKHKGTYRFVANN
| .. .....|||...  | .    .|.| .|.. || ...|  ..  . ... .| | .| | ... |||. ||.|
Pvisvspsptvtsggn..vtLtCsaeggpppptisWy.ietppelqgsegssssestLtissvtsedsGtYtCvasN

subfamily_Anemone-PTP-4_pd Subfamily Anemone-PTP-4 901-989 2.7e-07 25.1 In-house 135-224 (237) alignment
Range on Protein: 901-989
Range on HMM: 135-224/237.0
VTQFQITNWGSTGEVKNPQTILMIMEEMYRTQRKR-GNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQT
. |.|.| |   |  ..  ..| .  ..    ..    .  ..|||  |||...|    . . ..| . |.|... ..|   ..|  .||
ihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlrqakekkvvdiynyvysieedrpyiiqt

0044763 (Phosphotyrosine protein) phosphatases II 902-989 6.6e-07 24.6 In-house 76-156 (178) alignment
Range on Protein: 902-989
Range on HMM: 76-156/178.0
TQFQITNWGSTGEVKNPQTILMIMEEMYRTQRkRGNTSIVVHCSDTVGRSAMFCAAATTINKckteGViDVFQVLKSQRIQKPgSVQT
 |.. ...   |.   .. .| ..| . . .  . .  ..||||  ||||....||   .      |. .......  | ..|  |..
iqylhipipDhgvpdllehflefvefieeald.ekggpvlVHCsaGvgRsgtlvaaylmkkl....gl.sleeaielvrerRp.ivpn

Ig_2 Immunoglobulin domain 715-789 9.3e-07 20.8 Pfam-A 12-80 (80) alignment
Range on Protein: 715-789
Range on HMM: 12-80/80.0
EEGCQVHFKVKFKGTPTPFFNWYHNGEPVTDDYAHelrgdgsLLLVSVEEKHKGTYRFVANN-EAGTVSQQVVLTV
.||..| .  ...| ||| . ||..||...   .        |.. .|.....|||. .| | | ...|. | .||
tegenvtLtCqapgnptpkvqwykdgeelsqsqna.......lfipnvsaedsGtYtCrasnsegskqsnsvevtv

subfamily_Sponge-PTP6_pd Subfamily Sponge-PTP6 898-991 1.4e-06 22.0 In-house 173-266 (439) alignment
Range on Protein: 898-991
Range on HMM: 173-266/439.0
KQSVTQFQITNWGSTGEVKNPQTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVV
...| ||. . |       .   .|  .  .  .. |.    .|||||  |||.    |   .... |.|  .|.  ..|  | |.   ||...
ertvlqfhyiawpdknvpaqashvldflrainsandkeeygpvvvhcsagvGrtGtiialdialeqlklenkvdikgivkvlrkqrkqmvqalc

subfamily_Fungi-PTP1_pd Subfamily Fungi-PTP1 901-959 1.8e-06 21.9 In-house 217-284 (350) alignment
Range on Protein: 901-959
Range on HMM: 217-284/350.0
VTQFQITNWGSTGEVKNPQTILMIME--------EMYR--TQRKRGnTSIVVHCSDTVGRSAMFCAAAT
| |.|. ||   . . ||. || ..|         . .   . .|. ..|.||||  |||  ....   
vyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnars.spilvhCsaGvGrtGtlvtlDs

subfamily_Nvec-PTP-2_pd Subfamily Nvec-PTP-2 849-895 2e-06 22.2 In-house 3-47 (250) alignment
Range on Protein: 849-895
Range on HMM: 3-47/250.0
VGLTSSNKLLNRFANIVVYDDNRIILRPISGHKDCpnEYVNACYVDT
|.   .||  ||.|.|. .|  |..| . .| |..  .|.|| ....
vakkpqnkeknryadiialdssrvvLekekgdkes..dyinasflhg

subfamily_hpo-7_pd Subfamily hpo-7 899-999 2e-06 21.9 In-house 122-222 (263) alignment
Range on Protein: 899-999
Range on HMM: 122-222/263.0
QSVTQFQITNWGSTGEVKNPQTILMIMEemyrTQrkRGNTSIVVHCSDTVGRSAMFCAAATTIN-------KCKTeGVIDVFQVLKSQRIQKPGSVQTVV
. |.... . |  . ...... || |..        |.  |.|||||  .|||| |  | .          . .| . .|  ..|.  | .......| .
htvkhysykgWiekndpelareilnilk....va..rnskslvvhcstGiGrsaafsvaElvyqkmirsldttst.veldylsLleelrssrkraihtPm

SINYSCYI
 . .| ..
qLafsilm

TMEM154 TMEM154 protein family 611-695 2.8e-06 18.7 Pfam-A 52-136 (146) alignment
Range on Protein: 611-695
Range on HMM: 52-136/146.0
NGGSMTIVFIAVGAIVslLLIVIIIVIIIVVVLKKERFKKD--YDIVSSKNKPVTAEQNLTPYSTFNNNNGGYEEIGLERIQEATYS
.    ... |.. ..|  | .....|.|.|.. |. | |..   .  ... .    ...  . . | ..     || .| ...  .|
adqaelvlmiiiPsvv..LillllvvvilvikkkrkrrKqeetsedekedlqldeldsenvkvpifEedvpsvmeiEmeeldkwmns

subfamily_Choan-PTP-4_pd Subfamily Choan-PTP-4 924-992 3.5e-06 21.1 In-house 216-283 (297) alignment
Range on Protein: 924-992
Range on HMM: 216-283/297.0
IMEEMYRTQRKRgNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVVS
.  | .|..  | |. ..||||  |||| .   . . ..| . . . ||  .|.  | |..  |||.  
lqleslraempr.nayllvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqtleq

subfamily_Cele-PTP-6_pd Subfamily Cele-PTP-6 897-992 4e-06 21.1 In-house 174-265 (307) alignment
Range on Protein: 897-992
Range on HMM: 174-265/307.0
AKQSVTQFQITNWGSTGEvknPQTILMIMEEMYRTqRKRgNTSIVVHCSDTVGRSAMFCAAATTINKC-KTEGVIDVFQVLKSQRIQKPGSVQTVVS
  ......| .||   |    ||. |  .. .  . |   .  .|||||  ||||    | .   .|  . .   |. ....  | |.. ..|| . 
ksrtiqhlqwenwpdrgv...pqinltainlleav.ryd.tnpvvvhcsaGvGrsGtivaislvqdkmiaGinckdmkklveelrsqrhyaiqteaq

subfamily_Cele-PTP-9_pd Subfamily Cele-PTP-9 899-999 4.8e-06 20.8 In-house 116-216 (255) alignment
Range on Protein: 899-999
Range on HMM: 116-216/255.0
QSVTQFQITNWGSTGEVKNPQTILMIMeemyRTQRKRgnTSIVVHCSDTVGRSAMFCAAATTIN-------KCKTeGVIDVFQVLKSQRIQKPGSVQTVV
. |. .. . |      .... || |.    .  |.    |.|||||  .|||| |  |            . .| . .|  ..|.  | .......| .
htvkhysykGWieknaPelareilnil....kvvrds..ksvvvhCstGiGrsaafvlaelvyqkmirsldttet.veldylslleelrskrkraihtPl

SINYSCYI
 . .| ..
qlafsilm

subfamily_Urchin-PTP-1_pd Subfamily Urchin-PTP-1 811-894 5.2e-06 20.5 In-house 3-81 (315) alignment
Range on Protein: 811-894
Range on HMM: 3-81/315.0
VPVGQFGEFVANGhaKGNEGFRNQFMMLDSGESdHSVTVGLTSSNKLLNRFANIVVYDDNRIILRPISGHKDcpNEYVNACYVD
.|| ||  || .   .    | ..|  |   .  .  .|. .. |   ||. ||. .| .|..|  |  . |  ..|.|| |. 
ipvaqfpafvnkn..rhtalfseefhdlpdPdi.yrqrvaretinfkknryknilPldsarvkleviddsPd..sdyinasyik

subfamily_Urchin-PTP-4_pd Subfamily Urchin-PTP-4 811-894 6.2e-06 19.9 In-house 4-82 (392) alignment
Range on Protein: 811-894
Range on HMM: 4-82/392.0
VPVGQFGEFVANGHAkgNEGFRNQFMMLDSGEsDHSVTVGLTSSNKLLNRFANIVVYDDNRIILRPISGHKDcpNEYVNACYVD
.|| ||  || . .   .  | ..|  | . .  .  ||. .  |.  ||. ||. || .|..|  |    |  ..|.|| |..
ipvaqfpafveknrh..salffeefhdlpgpd.iypqtvaqkeinlkknryknilpydsarvkleviddipd..sdylnasyip

subfamily_Cele-PTP-1_pd Subfamily Cele-PTP-1 895-991 6.5e-06 20.5 In-house 154-246 (290) alignment
Range on Protein: 895-991
Range on HMM: 154-246/290.0
TGAKQSVTQFQITNWGSTGEVKNPQTILMIMEEMyrtqrKRGNTSIVVHCSDTVGRSAMFCAAATTINKCK-TEGVIDVFQVLKSQRIQKPGSVQTVV
 . .  ||  .. .| ..   ....|.| ... .     |  .| ..||| | . |||.. |      |   |.| . . .|||. | |.   ...  
deeeftvtHsllkgWnklnvqedtktllsliqkv.....kasktpvivHcvdGiSrsAalaaiilgyQkiaetsgsvkledvlkalrkqralaitsal

subfamily_Sponge-PTP5_pd Subfamily Sponge-PTP5 824-894 9e-06 19.8 In-house 4-66 (283) alignment
Range on Protein: 824-894
Range on HMM: 4-66/283.0
HAKGNEGFRNQFMMLDSGESDHSVTVglTSSNKLLNRFANIVVYDDNRIILRPISGhkdcpnEYVNACYVD
....|. ||...  |   . |  ...  .. ||  ||. .||..| .|. |.. |       .|.||... 
rvnnnklfrevlkrlsvpdldadias..adenkrknrnqeivpadqwrvelksesr......dyinavfip

subfamily_PTPN9_pd Subfamily PTPN9 818-899 9.9e-06 19.8 In-house 5-83 (297) alignment
Range on Protein: 818-899
Range on HMM: 5-83/297.0
EFVANGHAKGNEGFRNQFMMLDSGESDHSVTVGLTSSNKLLNRFANIVVYDDNRIILRPISGHKdcPNEYVNACYVDtGAKQ
|.||  ..||..| ..... . . .    ...  . .|   ||..... ||. |. |  .....    .|.|| .|| | ||
elvayvkekgkrGlskeyaeirnepveGtflasklranleknrytdvlcydetrvvlakvdede..asdyinanfvd.Gykq