Gene PTPRD-28 in Amphimedon queenslandica

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family PTP
Subfamily PTPRD
Protein sequence
ID Type Fasta BLAST phosphatome Note
AqueP082_AA protein Get Run
AqueP082_AA_849-1037 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_Sponge-PTP11_pd Subfamily Sponge-PTP11 931-1043 2.5e-65 215.2 In-house 178-290 (290) alignment
Range on Protein: 931-1043
Range on HMM: 178-290/290.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQ
.||||.|||||||||.|.||||||...||||.||||||||||||||||||||||.|||||||||||||||||||||||||||||||||||||||||||||
qsvtqyqitnwdstgkvtnpqtillvieemyktqrkrgntsivvHCSdtvgrsavfcaaattinkcktegvidvfqvlksqRiqkpgsvqtvqqyqgifq

IVLTYLDSFETYS
|||||||||||||
ivltyldsfetys

subfamily_Sponge-PTP10_pd Subfamily Sponge-PTP10 931-1045 4e-64 211.3 In-house 173-287 (287) alignment
Range on Protein: 931-1045
Range on HMM: 173-287/287.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQ
..|.|.|||||||||.|..|||||...||||.||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||.||..|..
qqvkqyqitnWdstgkvtepqtillvieemyktqrkrgntsivvhCsdtvGrsamfcaaattinkckteGviDvfqvlksqriqkpgsvqtveqykfind

IVLTYLDSFETYSNF
|||.|||||||||.|
ivleyldsfetysdf

subfamily_Sponge-PTP11_pd Subfamily Sponge-PTP11 846-930 5.5e-41 135.3 In-house 1-85 (290) alignment
Range on Protein: 846-930
Range on HMM: 1-85/290.0
LIPVGQFGKFVANGHAKGKERFKTQFMMLDSGESEHSVTVGLSPSNKLLNRFANIVVYDENRITLRPISGHKDCPNEYINACYVD
||||..||.|||||||||.|.|..||.|||||||||.|||||..|||||||||||||||.||||||||||||||.||||||||..
lipvdkfgefvanghakgnegfrnqfkmldsgesehtvtvgltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyik

0051299 (Phosphotyrosine protein) phosphatases II 845-1036 5.6e-40 133.0 In-house 3-286 (288) alignment
Range on Protein: 845-1036
Range on HMM: 3-286/288.0
NLIPVGQFGKFVANGHAKGKERFKTQFMMLDSGESEHSVTVGLSPSNKLLNRFANIVVYDENRITLRPISGhkDCPNEYINACYVDR-------------
. |.| .. |.| . .|.|. ... .| .| |    ......| | |.  ||. .|. || .|. |....|  . .. |||| |.|              
teisveellklvlkllangltglleefeellsllpdltlsaallpenleknRysdilpydhsRVkLsvldg..vegsdYinAsyidgynlkrkfIatqgP

----------------------------------------------------------------------------------SVTQFQITNWDSTGEVKN
                                                                                   ||.|. |||   |   .
lpntvedFWrmvweqnvrvIvmltklvelgrekcaqYwplggsltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpds

PQTILMIMEEMYRTQRkRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYL
|. .| ....... ..  |.  .|||||. |||...|.|. . ..  ..||..||....|  | |.||.|||..||. .....| ||
pellldflrlvrkala.sgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyealleyl

0050432 (Phosphotyrosine protein) phosphatases II 854-1043 3e-39 130.6 In-house 33-306 (308) alignment
Range on Protein: 854-1043
Range on HMM: 33-306/308.0
KFVANghAKGKERFKTQFMMLDSGESEHSVTVGLSPSNKLLNRFANIVVYDENRITLrpisghkDCPNEYINACYVDRS---------------------
|.. .  |... .....|. | |    .. .|.| | || .||. .|. || .|. |       | .. |||| |||                       
kllek..aldlglleeefeellsvkplleysvallpenkdkNrykdilpydhsRVkl.......degsdYInAsyvdgyssklprkfIatqgPlpntved

---------------------------------------------------------------------------VTQFQITNWDSTGEVKNPQTILMIM
                                                                           ||.|. |||   |   .|. .| ..
FwrmvweqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseevlddytvrtleltnlgdgesrtvthfhytnWpdhgvPpspeilldfl

EEMYRTQrkrGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYLDSFETYS
|.. ...   ..  ||||||. |||.. |.|. . ..  ..|| .|||...|  | |.||.|||..||. .....| || ...|. 
elvrksl...pggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylflyralleylklkltkl

subfamily_Sponge-PTP9_pd Subfamily Sponge-PTP9 931-1044 4.4e-37 122.4 In-house 188-301 (301) alignment
Range on Protein: 931-1044
Range on HMM: 188-301/301.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQ
..|.|.|.|.|   | |..|.|.|......  .|.| |   .||||||||.|| ..|.   ..  || |||.||||| |. | .||| |.| .||  |..
wdvlqlqvtdWpqdGvvreprtvLqviddvihrqqkigggpvvVHCSdtVsrsGvYcsvsiglEQckaegVVdvfqvtkavrrskpgaVtTLeqytsiyd

IVLTYLDSFETYSN
.. .||   .||.|
vidmylqlnstyan

0046845 (Phosphotyrosine protein) phosphatases II 867-1044 9.8e-37 122.3 In-house 2-282 (284) alignment
Range on Protein: 867-1044
Range on HMM: 2-282/284.0
FKTQFMMLDSGESEH--SVTVGLSPSNKLLNRFANIVVYDENRITLRPISGHkDCPNEYINACYVDRS--------------------------------
.. .|..| |    .  |..|.| | |. .||. .|..|| .|. |....|. .  ..|||| |||                                  
leeefeellsltvklllslsvallpenlsknRykdilpydhsRVklksldgd.ledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweq

------------------------------------------------------------------VTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRK
                                                                  ||.|..|.|   |   .|. .| ..... . ...
nvrvIVmltelvengrekcaqYwplegevltygdftvtllseevkddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrellen

-RGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEG---VIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYLDSFETYSN
  |.  ||||||. |||...|.|. . ..  ..||   ..||....|  | |.||.|||..||. .....| || .. |. .
lpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleylklkltlle

0036941 (Phosphotyrosine protein) phosphatases II 861-1043 5.1e-36 119.9 In-house 9-284 (297) alignment
Range on Protein: 861-1043
Range on HMM: 9-284/297.0
AKGKERFKTQFMMLDSGESEHSVTVGLSPSNKLLNRFANIVVYDENRITLrpisghKDCPNEYINACYVD------------------------------
.... .....|. |..     | .|.|.| |. .||. .|. || .|. |      .| .. ||||.|||                              
llflalllkefeellpllllgslsvallpenleknRykdilpydhtRVkl......ddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqn

-----------------------------------------------------------------RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQR
                                                                 | ||.|..|.|.  |   .|...| ..|.. . ..
vtvIvmltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrkvlk

KR-GNTSIVVHCSDTVGRSAMFCAAATTINKCK---TEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYLDSFETYS
.  ... ..||||. ||||..|.|| . ..  .   .|| .|.....|. | |.||.|||..||. . ...| .| ...|. 
llpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallellkkkltke

0047943 (Phosphotyrosine protein) phosphatases II 860-1036 1.2e-35 118.8 In-house 7-272 (273) alignment
Range on Protein: 860-1036
Range on HMM: 7-272/273.0
HAKGKERFKTQFMMLDSGESEHSVTVGLSPSNKLLNRFANIVVYDENRITLrpisghKDCPNEYINACYVDR----------------------------
...|. ... .| .| |   ... .|.| | || .||. .|. || .|. |      .| .. |||| |||                             
kllgltllleefelllslkplltysvallpenkdknrykdilpydhsrvkl......gdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvweq

------------------------------------------------------------------SVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQR
                                                                   ||.|. |.|   |   ... .| ..|.. ....
nvrviVmLtelvelgrekcaqYwpleggelsltygkftvtllseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvrkale

KR-GNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYL
.  .|. .|||||. |||...|.|. . ..  ..|| .||....|  | |.||.|||..||. . ...| ||
alpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyealleyl

0040438 (Phosphotyrosine protein) phosphatases II 851-1043 1.3e-35 118.7 In-house 4-283 (317) alignment
Range on Protein: 851-1043
Range on HMM: 4-283/317.0
QFGKFVANGHAKGKERFKTQFMMLDSGESEhSVTVGLSPSNKLLNRFANIVVYDENRITLRPISGhkDCPNEYINACYVD--------------------
.. ...   ..... ... .|..|.|   . . .|.. | || .||. .|. || .|. | |..|  | .. |||| |||                    
dlllalldllksdftalleefedllslkld.tysvaelpenkdknrypdilpydhsRVkLsplgg..dldsdYInAsyvdgpnlkrkfIatqgPlpntve

-----------------------------------------------------------------------RSVTQFQITNWDSTGEVKNPQTILMIMEE
                                                                       | ||.|. |.|.  |  ..|...| ..|.
dFwrmvweqgvtvivmLteleelgrekcaqYwplgetltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldflea

MYRTQRkRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYLDSFETYS
. . .. .... ..||||. |||...|.|| . .. ...|| .||....|  | |.||.||| .||. . ...| ||  ..|. 
vreale.dpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleylkrkltle

0045450 (Phosphotyrosine protein) phosphatases II 846-1036 2.2e-35 118.3 In-house 8-304 (307) alignment
Range on Protein: 846-1036
Range on HMM: 8-304/307.0
LIPVGQFGKFVANGHAKGKERFKTQFMMLDSGES--EHSVTVGLSPSNKLLNRFANIVVYDENRITLRPISGHkDCPNEYINACYV--------------
.|.. .. ..|.  ......... .| .| | .    .. ...|.| || .||. .|. || .|. | ...|. . .. |||| ||              
fidalkllllvllllldfltgllkefekllsvtvfllgeysiallpenkdknrykdilpydhtRVklssldgs.ledsdYiNAsyvrvpllllldgydlk

---------------------------------------------------------------------------------------DRSVTQFQITNWD
                                                                                        | ||.|. |.| 
rkfIatqgPlpetvedFwrmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwp

STGEVKNPQTILMIMEEMYRTQRKR-GNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGV---IDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYL
 .|  ......| ..||. . ...  ... ..||||. |||...|.|| . .   ..||.   .|.....|  | |.||.||. .||. . ...| .|
dhgvppsfeelldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeallell

0039614 (Phosphotyrosine protein) phosphatases II 848-1040 5.3e-34 113.4 In-house 15-293 (297) alignment
Range on Protein: 848-1040
Range on HMM: 15-293/297.0
PVGQFGKFVANGHAKGKERFKTQFMMLDSGESEhsVTVGLSPSNKLLNRFANIVVYDENRITLRPISGHkDCPNEYINACYVD-----------------
|.. .  ..   .|..| .....|..| |   .   ...|.| || .||. .|. || .|. | |. |. | .. |||| |||                 
plsvldlllllekansktllllefeellslkpd..ysiallpenkdknrykdilpydhsrvklkpedgv.dldsdYinAsyvdgydlltrkfIatqgPlp

-----------------------------------------------------------------------RSVTQFQITNWDSTGEVKNPQTILMIMEE
                                                                       | ||.|| |.|   |   .....| ..|.
etvedFwrmvweqgvtvivmLtklvelgrkcaqywpeeggtygdftvtllkvehldgytvrtlevtnngesrtvthfqytgwpdhgvppslellleflel

MYRTQRKR-GNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYLDSFE
. . ...  ... ..||||. |||...|.|| . .. ...|| .||....|  | |.||.||| .||. .....| .|  . 
vrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydallellkrkl

0043336 (Phosphotyrosine protein) phosphatases II 847-1036 7.8e-33 109.5 In-house 2-277 (278) alignment
Range on Protein: 847-1036
Range on HMM: 2-277/278.0
IPVGQFGKFVANGHAKGKERFKTQFMMLDSGESeHSVTVGLSPSNKLLNRFANIVVYDENRITLRPISGHKDcpNEYINACYVDRS--------------
|.| .. |.... ....| ... .|  |.|     . ...|.| || .||. .|. || .|. | ...|. |  . |||| |||                
isvkdllkallelllnlktllllefeellsfkl.dtysiallpenkdknrykdilpydhsrvklsllggdld..sdYinAsyvdgynvprkfiatqgPlp

----------------------------------------------------------------------------VTQFQITNWDSTGEVKNPQTILMI
                                                                            ||... ..|   |   .....| .
etvedFwrmvwelgvttivmLtelvelgrvkcaqYwpggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldf

MEEMYRTQRkRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYL
.... . ..   |. ..||||. |||...|.|. . ..  ..|| .|.....|  | |.||.||| .||. .....| ||
lkavreale.dsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyealleyl

subfamily_Sponge-PTP8_pd Subfamily Sponge-PTP8 930-1041 1e-31 105.2 In-house 177-288 (305) alignment
Range on Protein: 930-1041
Range on HMM: 177-288/305.0
DRSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIF
.|.|.|.|.|.|   | .. . ..| ..... ..|.|  .....||||..|||. .|.|    ....|.|.|.|||.|||  | .... ||| .||. ..
srtvlqyqltdWPdhGvpqfatsllslikrvqkdqkkdkgvpllVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkmvqtldqYvflh

QIVLTYLDSFET
...  .. ...|
daldelitcgdt

subfamily_Anemone-PTP-2_pd Subfamily Anemone-PTP-2 931-1042 8.9e-31 102.2 In-house 185-296 (298) alignment
Range on Protein: 931-1042
Range on HMM: 185-296/298.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQ
|.| |.. |.| . |. .| ...| ..... ..|.. ||....|.||. ||||  |.|  . ... |.| |.|||||.|  |...||.||| .||  |..
revrqlhftsWpdkgvpenatsvldllrkvrasqqqagnkpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiye

IVLTYLDSFETY
.|| .||||...
avlealdsfnde

subfamily_Sponge-PTP10_pd Subfamily Sponge-PTP10 846-930 3.7e-29 96.6 In-house 1-80 (287) alignment
Range on Protein: 846-930
Range on HMM: 1-80/287.0
LIPVGQFGKFVANGHAKGKERFKTQFMMLDS-GESEHSVTVGLSPSNKLLNRFANIVVYDENRITLRpisghkDCPNEYINACYVD
||||..||.|||.|||||.| ||.||..|.. ...|..||......|| .||...|.|.|..|. |.      .. ..||||...|
lipvekfgefvakghakgnegfknqftvleqvtqredevthniasqnkdknRltqilvpdnyrvllk......gehpdyinavfid

0042113 (Phosphotyrosine protein) phosphatases II 885-1036 5.5e-29 96.7 In-house 3-243 (245) alignment
Range on Protein: 885-1036
Range on HMM: 3-243/245.0
VGLSPSNKLLNRFANIVVYDENRITLRPISGHKDCPneYINACYV-------------------------------------------------------
|.| | || .||. .|. || .|. | |..|. |..  ||||.||                                                       
vallpenkdknrysdilpydhtrvklspdggdldsd..yinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywpl

------------------------------------DRSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTI
                                     | |.... ..|.  |.  .....| ..|.. . ... .|. ..||||. |||...|.|| . .
gesltygdftvtllseehlddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylml

NKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYL
.  ..|. .......|  | |.||.||| .||. . ...| .|
eqlekelgvsleeavkelrsqRpgavqtpsqyrflyeallell

0045098 (Phosphotyrosine protein) phosphatases II 871-1037 3.5e-28 94.2 In-house 13-273 (278) alignment
Range on Protein: 871-1037
Range on HMM: 13-273/278.0
FMMLDSGESEHSVTVGLSPSNKLLNRFANIVVYDENRITlrpisghkdcpnEYINACYVD----------------------------------------
|  | .  .  ..|..| ..|. .||. .|. || .|.             .|||| |.|                                        
fefllllgipseitpalylgnldknRykdilpydhsrVk............dYINAsyidgypkkfIatqgPlpstvadfwrmlwelgitvivmltelve

-----------------------------------------------------RSVTQFQITNWDSTGEVKNP--QTILMIMEEMYRTQR----------
                                                     | ||......|.  |   .|  . .| ..|.. . ..          
lgrekcaqywpeggsltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllssl

--KRGNTSIVVHCSDTVGRSAMFCAAATTINKCktEGVIDVFQVLKSQRIQKPG-SVQTVQQYQGIFQIVLTYLD
    ... ..||||  |||.....|| . .  .  ||..|.....|  | |.|| .||. .||. ... .| .| 
llldsggpvlVHCsaGvgRtGtlvaaylmlell..eggvdlleavkelrsqRpglavqnleqyrflyefllelll

subfamily_PTPRD_pd Subfamily PTPRD 931-1042 7.7e-28 92.4 In-house 177-287 (564) alignment
Range on Protein: 931-1042
Range on HMM: 177-287/564.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQrKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQ
| |.||. |.| ..|  ......| ..... ... ....  ||||||  |||. .|..    ... |.|...|..|..|  | |..  ||| .||. |..
reVrqFhFtsWPdhgvpesatslLdlirkvraln.epdagPivVhCSaGVGRTGtfividamlerikeektvDiyqyvkalrkqRnamVqteeQYiFihe

IVLTYLDSFETY
..| .|....| 
ailealacgnte

subfamily_Anemone-PTP-6_pd Subfamily Anemone-PTP-6 930-1044 9.3e-28 92.2 In-house 174-288 (318) alignment
Range on Protein: 930-1044
Range on HMM: 174-288/318.0
DRSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIF
 | | |...|.|  .|  ... ..| .. .  ..|.| |.. ||||||  |||  .|.|  . ... | |...||||. |  | |..  ||| .||. |.
srqvrqyhytsWpdegvpesgaslldlvrqvskaqqksgagpivvhCsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqtedqyefiy

QIVLTYLDSFETYSN
...| .| |..|. .
dvllealasgdtevd

0040439 (Phosphotyrosine protein) phosphatases II 883-1036 1e-27 92.7 In-house 3-246 (249) alignment
Range on Protein: 883-1036
Range on HMM: 3-246/249.0
VTVGLSPSNKLLNRFANIVVYDENRITLRPISGhkDCPNEYINACYVD----------------------------------------------------
..|.| | || .||. .|. || .|. | ...|    .. |||| |.|                                                    
ysvallpenkdknrypdilpydhsrvklsilpg..lflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqyw

---------------------------------------RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRKR-GNTSIVVHCSDTVGRSAMFCAAA
                                       | |...|.|.|  .|  ......| ..|..   ...   .. ..||||. |||...|.|| 
plggsleygdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaay

TTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYL
. ..  ..|. .|.....|  | |.||.||. .||. . ...| .|
lmleqlekelgvdleeavkllrsqRpgavqnpeqyrflyeallell

subfamily_Nvec-PTP-2_pd Subfamily Nvec-PTP-2 931-1044 1.2e-27 91.8 In-house 137-250 (250) alignment
Range on Protein: 931-1044
Range on HMM: 137-250/250.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQ
| | |.. ..|   |  .. ...| ..... ..|.. ||. ..|.||  ||||  |.|  . ... |.| |.|||.|.|  |...|..|.. .||  ...
rivrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidavlerlkkekvvdvfkvikvlrkdrphavesleqyvfvye

IVLTYLDSFETYSN
|.| .|||.| |..
iilkaldsvedyar

subfamily_Anemone-PTP-5_pd Subfamily Anemone-PTP-5 931-1041 2.4e-26 87.6 In-house 178-288 (319) alignment
Range on Protein: 931-1041
Range on HMM: 178-288/319.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQ
|.|..|| |.|   .  .. ...| ..... ....|  .  ||||||. |||   |..   .... | |||.|||.. .  |.|..  ||. .||. |..
RevkhfqyteWpdhdvPekatslldllkrirksrektqsgPivvhCsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiye

IVLTYLDSFET
..| ......|
alleaveagdt

subfamily_Urchin-PTP-2_pd Subfamily Urchin-PTP-2 847-1036 4.4e-26 86.2 In-house 6-194 (440) alignment
Range on Protein: 847-1036
Range on HMM: 6-194/440.0
IPVGQFGKFVANGhaKGKERFKTQFMMLDSGESEHSVTVGLsPSNKLLNRFANIVVYDENRITLRPISGHKDcpNEYINACYVD----RSVTQFQITNWD
| | .|  .| |   .    |. .. .| || |. |   .| |.||. ||. ||..|| .|. |  . |  |  ..|||| |..    |.. |..   | 
iivadfadyvqnn..rrsrafedewsllpsglsqpsdiasl.pnnkvknryrnilaydhsrvmleevkgvpd..sdyinasyingiesrtlkqyhyqgwp

STGEVKNPQTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYL
  |  |    .| .....  .| | ||  ..||||  .||...  |  . . ..|    ||.| ...| | ..|  ||| .||  ... ||  |
dkgvpkfagpvlkmiqdvnesqekagngpllvhcsagagrtgviiavdsilreakrsdqidifsfinsmrnnrpqmvqtpeqyafvheavlegl

Y_phosphatase Protein-tyrosine phosphatase 931-1033 3.5e-24 80.9 Pfam-A 133-234 (235) alignment
Range on Protein: 931-1033
Range on HMM: 133-234/235.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQrKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQ
|.|.|...|||   |  ..|. .| ..... ... .  ....|||||. |||...|.|. . ......|. .||.|..|. | |.||.||...||. . .
revkqlhytnWpdhgvpespkslldlirkveksk.eaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmvqsleqYiflyk

IVL
..|
ail

Y_phosphatase Protein-tyrosine phosphatase 931-1033 3.5e-24 80.9 In-house 133-234 (235) alignment
Range on Protein: 931-1033
Range on HMM: 133-234/235.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQrKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQ
|.|.|...|||   |  ..|. .| ..... ... .  ....|||||. |||...|.|. . ......|. .||.|..|. | |.||.||...||. . .
revkqlhytnWpdhgvpespkslldlirkveksk.eaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmvqsleqYiflyk

IVL
..|
ail

subfamily_Sponge-PTP5_pd Subfamily Sponge-PTP5 933-1034 4.3e-24 79.9 In-house 164-264 (283) alignment
Range on Protein: 933-1034
Range on HMM: 164-264/283.0
VTQFQITNWDSTGEVKnPQTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIV
.. .|. .| . ||   .   |. .. .   |..  .. |||||| ..||.|.|.||...... .|| |.|||.|.|  | |... ||| .||. . ..|
lahyqvidWleygeqa.iinslvkfnkvislqteskkgPivvhCstgiGrtavfiaasasvkdaltesvvdvfavvkimreqrmmavqtldqyklvhelv

LT
| 
le

subfamily_PTPRA_pd Subfamily PTPRA 931-1035 7.8e-24 79.2 In-house 191-294 (330) alignment
Range on Protein: 931-1035
Range on HMM: 191-294/330.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRKRGNtSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQ
| |.||  | |   |   .|. .| ..... ..... .. .||||||  |||.  |..  . ... |.|...|||...|. | |.|  ||| .||. |..
rlvrqfhftswPdvGvPfepiGmlkllkkvkklnqqsag.pivvhcsaGvGrtGtfivldavlervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiyk

IVLTY
..| |
vlley

DSPc_SM00195 931-1036 7.9e-23 76.5 In-house 158-262 (263) alignment
Range on Protein: 931-1036
Range on HMM: 158-262/263.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRKRgNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQ
|.|||.|..||   |  .... .| ...... ....  .. ||||||. |||...|... . ..|...|  .|.|...|. | |.||.||| .||. | .
rkvtqyqyknWpdhgvpdstksvlellravkksksts.sgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiye

IVLTYL
..| |.
aileyi

PTPc_SM00194 931-1036 7.9e-23 76.5 In-house 158-262 (263) alignment
Range on Protein: 931-1036
Range on HMM: 158-262/263.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRKRgNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQ
|.|||.|..||   |  .... .| ...... ....  .. ||||||. |||...|... . ..|...|  .|.|...|. | |.||.||| .||. | .
rkvtqyqyknWpdhgvpdstksvlellravkksksts.sgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiye

IVLTYL
..| |.
aileyi

0037934 (Phosphotyrosine protein) phosphatases II 884-1035 9.8e-22 73.1 In-house 3-241 (243) alignment
Range on Protein: 884-1035
Range on HMM: 3-241/243.0
TVGLSPSNKLLNRFANIVVYDENRITLrpisghKDcpNEYINAC--------------------------------------------------------
...|.| |.  ||. .|. || .|. |      ..  . ||||                                                         
siallpenlsknrysdilpydhsrvkl......eg..sdyinanliyvtprliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqyw

-----------------------------------YVDRSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRK-------RGNTSIVVHCSDTVGRSAM
                                   .. | |.... ..|   |   .|. .| ...|..  ...        ..  ..||||  |||...
pgevtygdftvtllseehlddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGt

FCAAATTINKCkteGvIDVFQVLKSQRIQKPG-SVQTVQQYQGIFQIVLTY
..|| . . ..   | .|.....|  | |.|| .||| .||. . ...| .
liaaylmllll...g.vdleeavkllreqRpgkavqtpsqyrflyeallel

PTPc_DSPc_SM00012 933-1032 3.1e-21 70.9 In-house 2-103 (105) alignment
Range on Protein: 933-1032
Range on HMM: 2-103/105.0
VTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRKRG-NTSIVVHCSDTVGRSAMFCAAATTINKCKTE-GVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQ
|.....|.|  .|  .... || ..... . ..|.. ....|||||. |||...|.|... ......| . .|.||..|. | |.||.||| .||. . .
vkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylflyr

IV
..
al

subfamily_PTPRK_pd Subfamily PTPRK 931-1034 5.2e-19 63.2 In-house 173-275 (314) alignment
Range on Protein: 931-1034
Range on HMM: 173-275/314.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRKrGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQ
| | ||| ..| . .  .. ...| .. ..  .| . ..  ||||||   ||. .|.| .. ..  ..|||.|||.. |. | .|.  |.| .||. |..
revrqfqflgWpdhdvPvsatgllklvrrvkksqee.eaGrivvhCsaGaGrtGtfiaidivldmieregvvdvfnavktlrsrkvnmveteeqykfiyd

IVLT
..| 
vile

subfamily_Urchin-PTP-6_pd Subfamily Urchin-PTP-6 931-1037 5.2e-19 62.7 In-house 172-277 (515) alignment
Range on Protein: 931-1037
Range on HMM: 172-277/515.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMyRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQ
| ||||. |.|   |  |. ...| .. |. .... . . ....|||  |||  .....   . . ||  ..|||....  | ..|  ||| .||  |..
rtvtqfhfteWPdkGvpkhtssllklikev.kadhgqythpliihcsaGvGrtGvvisidsvvahakttrmvdvfnfvtnirqkrpylvqtqeqyafiyg

IVLTYLD
.|| .| 
avledll

subfamily_Urchin-PTP-1_pd Subfamily Urchin-PTP-1 931-1037 5.7e-19 63.1 In-house 173-278 (315) alignment
Range on Protein: 931-1037
Range on HMM: 173-278/315.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTqRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQ
| ||||| |.|   |  |.  ..| .. |.    ... . |..||||  |||. .....   ... | . ..|||...|  | ..|  ||| ..|  |..
rtvtqfqftewPdkGvdkqtssllklikevkad.ngkkefsllvhcsaGvGrtGvvisidevvaqikrtrsvdvfnfvknlrakrpylvqteeeyafiyd

IVLTYLD
.|| .| 
avledll

subfamily_Ptp69D_pd Subfamily Ptp69D 931-1039 7e-19 63.1 In-house 182-289 (307) alignment
Range on Protein: 931-1039
Range on HMM: 182-289/307.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRKRgNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQ
| |.|.. |.|. .   . ....| ..|...  ...  .. ||||||  ||||..| | .  ....|.|  .|.|.. |  | |..  ||  .||. ...
rkvvqyhytgWkDskvPevargllklieqvrelykln.rsPivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnllvqsleqYvflyr

IVLTYLDSF
 .| | .  
alldyssyg

subfamily_Urchin-PTP-5_pd Subfamily Urchin-PTP-5 931-1041 8.9e-19 62.7 In-house 177-289 (297) alignment
Range on Protein: 931-1041
Range on HMM: 177-289/297.0
RSVTQFQITNWDSTGEVK--NPQTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGI
| | |.| ..| .  . .  . ...| ...|.  .  .. .. ..|||.  ||| .....    . . | |  .|.|...|  | ..|  ||| .||. .
rvvkqyqfveWPdkaverkdsassllklisevrkdfsqnaegPllvhclaGvGrtgvlltidsvvaeakrekevdifglvkklrqerpylvqtkeqykfv

FQIVLTYLDSFET
...|| .| | .|
yvavleallsedt

subfamily_Choan-PTP-1_pd Subfamily Choan-PTP-1 931-1038 1.9e-18 61.5 In-house 170-278 (281) alignment
Range on Protein: 931-1038
Range on HMM: 170-278/281.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTE-GVIDVFQVLKSQRIQKPGSVQTVQQYQGIF
|.|.|.. |.|  .|  .... .|   .|......|. ....|.|||  |||.  . |  . ......|   .|| .|... | ..   |||| ||. ..
reveqlaytaWPdhGvPattkellefrkevlkltekktkaplvihCsaGvGrtGtyialDrlvkaveaeleeldvkavvaelrkernlmvqtvvqyefvy

QIVLTYLDS
..|| .|| 
kavldaldk

subfamily_PTPN5_RR_pd Subfamily PTPN5_RR 927-1037 2.9e-18 60.9 In-house 157-269 (274) alignment
Range on Protein: 927-1037
Range on HMM: 157-269/274.0
CYVDRSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRKRGNT--SIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQ
.   |||. .  |.|  .   ....|.| ...|. ...... .   ..|||||  .||  .| |.  .... . |.|.||...    |... | ||| .|
lerersvkhywytdWPdhksPddantlldlvleveesreeenaklapvvvhCsaGiGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseq

YQGIFQIVLTYLD
|. |....  || 
yelihralclylk

subfamily_Urchin-PTP-7_pd Subfamily Urchin-PTP-7 931-1034 5.5e-18 59.9 In-house 175-277 (315) alignment
Range on Protein: 931-1034
Range on HMM: 175-277/315.0
RSVTQFQITNWDsTGEVKNPQTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQ
| | |...| |  . .| .  . || .    .  ..   ..||||||. |||.  |..  . ... ..| .|||.....  | .. . ||...||| |..
revvqlhytswp.dmgvpkytiplmnlirtvkqhhtnsvgaivvhcsaGvGrtGtfitldavldqaeaenaidvynfitgvrqnrikmvqvaeqyqfiyd

IVLT
..| 
alle

subfamily_Urchin-PTPRB-like_pd Subfamily Urchin-PTPRB-like 931-1040 5.7e-18 60.0 In-house 175-285 (288) alignment
Range on Protein: 931-1040
Range on HMM: 175-285/288.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRKRgNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQ
. .||.| . |  .|  .. . .| ... .  .. .     |.||||. |||.  | |. . |.. ..| .|||. ...  | |..  |||..||. |..
leitqyqylaWpdhgvPeskapllellrqvkvanqad.tgpiivhCsaGvGrtgtFialdalidaveeedyiDvagtvaklRkqRallvqtlkqYefiye

IVLTYL--DSFE
..|.    |. .
vllslieedgva

subfamily_Urchin-PTP-3_pd Subfamily Urchin-PTP-3 931-1038 5.8e-18 60.1 In-house 178-290 (325) alignment
Range on Protein: 931-1038
Range on HMM: 178-290/325.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMYR---TQ--RKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQY
||| |||.  ||  |  | | |.. |.. .     .     .. | |.||||. |||. .| .  . ..|  .|  .|.|...|  | ..|  |.|| ||
rsvkqfqlqswddmGvqkrpatlisilqlvkavservtantkastpilvhcsaGvGrtGvfislysalakvieesrvdifgfvkklrkdrpsmvetvdqy

QGIFQIVLTYLDS
  |.. .  .. |
iliyealveayms

0036282 (Phosphotyrosine protein) phosphatases II 925-1030 6.6e-18 60.4 In-house 61-164 (174) alignment
Range on Protein: 925-1030
Range on HMM: 61-164/174.0
NACYVDRSVTQFQITNWDSTGEVKNPQtILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKtEGVIDVFQVLKSQRIQKPGSVQTVQQ
.  .  |.. |.. ..|.  |.   .. .| ....... . . ..  ..||||  |||.....||   .   . |...|........| |.||.||| .|
lredlerlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtpsQ

YQGIFQ
|. . .
yrflyy

subfamily_Urchin-PTPRA_pd Subfamily Urchin-PTPRA 931-1033 3.8e-17 57.6 In-house 185-288 (319) alignment
Range on Protein: 931-1033
Range on HMM: 185-288/319.0
RSVTQFQITNWDSTGEVKNPQTILMIMEE-MYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIF
|..||| .  |   |  . |  ......   . |........||||||  |||. .. .  . ... | |  .||.....  | |..  || . ||. |.
rkitqfhflGwpdvGvpdypsdlmrlvkkvrhltskenhranivvhcsaGvGrtGvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiy

QIVL
  .|
sall

subfamily_PTPN12_pd Subfamily PTPN12 931-1036 3.9e-17 57.0 In-house 170-277 (290) alignment
Range on Protein: 931-1036
Range on HMM: 170-277/290.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMyRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGV---IDVFQVLKSQRIQKPGSVQTVQQYQG
|.|.||. |.|   |  ......| ..|.. |. ... .. .|||||  |||    .|   . .  |.| .   .|||... . | |..  ||| .||. 
rkvyqfhYtaWPDhgvPssaksllelielv.relqesedaPlvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyel

IFQIVLTYL
... |. ..
vykavaelv

subfamily_PTPRB_pd Subfamily PTPRB 931-1038 4e-17 57.2 In-house 179-287 (293) alignment
Range on Protein: 931-1038
Range on HMM: 179-287/293.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQ-RKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIF
|.|.|.. | |   |  ....|.| ..... ... ..  .. ||||||  |||.  | |  . ... ..| ..|.| .. . | ..   |||..||  | 
rkvrqyhftsWpdhgvPektktlldfvrtvreaiektaskrPivvhCsaGvGRtGtfialdrllqaieeedyvdifgivaelReeRnllvqtekqYifih

QIVLTYLDS
| ||..| .
qcvldllrk

subfamily_PTPRG_pd Subfamily PTPRG 931-1041 4.2e-17 56.6 In-house 183-292 (563) alignment
Range on Protein: 931-1041
Range on HMM: 183-292/563.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRKrGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQ
. |.|.. |.|  .|  . .   |. ..   .....     ||||||  |||. ....  | ... ..| ...||..||  | |..  |||  ||. ...
klvrqyhytkWPdhgvPehslpvLifvkkssaanka.eaGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvqteEqYiflhd

IVLTYLDSFET
..|  . | ||
alleaiasket

subfamily_Urchin-PTP-8_pd Subfamily Urchin-PTP-8 931-1034 5.5e-17 57.2 In-house 149-253 (284) alignment
Range on Protein: 931-1034
Range on HMM: 149-253/284.0
RSVTQFQITNWDSTGEVKNPQTILMIMEE-MYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIF
|...|| .  |   |  . |  ......   . |........||||||  |||. .. .  . ... | |  .||.....  | |..  || . ||. |.
rkirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrtgvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiy

QIVLT
  .| 
salle

subfamily_PTPN6_pd Subfamily PTPN6 931-1039 5.6e-17 56.7 In-house 186-300 (306) alignment
Range on Protein: 931-1039
Range on HMM: 186-300/306.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRKRG---NTSIVVHCSDTVGRSAMFCAAATTINKCKTEGV---IDVFQVLKSQRIQKPGSVQTVQQ
|.| |.. ..|   |  |.|...|  .|.. | |..     . .||||||. .||   |    . ... ...|.   ||. .. || | |. | ||| ||
revfqyhfksWPdhgvpkdpgavLdfledvnrkqeeleeaeagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqteqq

YQGIFQIVLTYLDSF
|. ..... .|... 
ykfvykaikkyietk

subfamily_CG7180_pd Subfamily CG7180 931-1036 6.3e-17 56.2 In-house 180-290 (296) alignment
Range on Protein: 931-1036
Range on HMM: 180-290/296.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRKRG-----NTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQY
| |..||.| |..  .|    . |. . .. |. |..      .  .||..|| ..|| ...|.  .... . |. .|||. .|  |...|. |..|..|
RivklfqlteWeledkvPlstnalielrrrvrlwrekvdedpeegPvvvvssdGasRsGvylaidanlelvekeeevdvFeavktlrrsRpqLvenveeY

QGIFQIVLTYL
. |....| ..
kyiYdvlleav

subfamily_Sponge-PTP1_pd Subfamily Sponge-PTP1 953-1034 9e-17 55.9 In-house 176-257 (267) alignment
Range on Protein: 953-1034
Range on HMM: 176-257/267.0
ILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLT
.  ..  . . | . ||  .||.||| ||||  |  . . ... ||||| |.|. |.  | |..| |.| ..|  | ...  
lkplfgilaknqlengnrPlvvacsdGvGrsGtflvidsqleraktegvsdifdflrkirsqriglvdtkeryiyihellae

subfamily_PTPN23_pd Subfamily PTPN23 931-1036 1.4e-16 55.2 In-house 171-280 (288) alignment
Range on Protein: 931-1036
Range on HMM: 171-280/288.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEM---YRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCK-TEGVIDVFQVLKSQRIQKPGSVQTVQQYQ
.||.  |.|.| . |  . |.|.| ...|.   |...... .| .|||||  |||. .|.   . ... .  .|..|. ||..  | |.  .||...|..
ksvshlqltsWpelGvPasPetllqfldevesayeavqrksktPlvvhCsaGvgRtgvfalvyaavrelekgnglldiiqvvsrlreqRrfmvqekeqlk

GIFQIVLTYL
  ...||.. 
fsyeavleaa

0043147 (Phosphotyrosine protein) phosphatases II 923-1029 2.5e-15 52.1 In-house 55-154 (172) alignment
Range on Protein: 923-1029
Range on HMM: 55-154/172.0
YINACYVDRSVTQFQITNWDSTGEVkNPQTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTInkckteG-ViDVFQVLKSQRIQKPGSVQT
. .. .. |.. |.. ..|.  |   ... .| ..| ... . .. .  ..||||  |||.....||   .        . .......  | ..||.||.
lydpellerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml......lgl.sleeavalvrekRpgavqn

VQQYQGIF
 .||. . 
psqyrfly

subfamily_PTPRD_pd Subfamily PTPRD 846-930 4.1e-15 50.4 In-house 4-85 (564) alignment
Range on Protein: 846-930
Range on HMM: 4-85/564.0
LIPVGQFGKFVANGHAKGKERFKTQFMMLDSGeSEHSVTVGLSPSNKLLNRFANIVVYDENRITLRPISGHKDCpnEYINACYVD
 ||| .. ..||. .|... .|....  ...| .......   | ||  ||.|||| ||..|. |... |....  .|||| ..|
pipvaelkehvaklkansdlkfeeeykkieeg.qqftweaankpaNkaKNRyanivaYdhsRVvLskvegdegs..DYINAsfid

0041856 (Phosphotyrosine protein) phosphatases II 891-1035 4.5e-15 51.2 In-house 1-170 (182) alignment
Range on Protein: 891-1035
Range on HMM: 1-170/182.0
NKLLNRFANIVVYDENRitlrpisghkdcPNEYINACYVD------------------------------------------------RSVTQFQITNWD
|. .||. .|. || .|            .. |||| ...                                                | ..|.. ..|.
nldknrysdilpydhsr............dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlteelywpellerlgiqylylpwp

STGEVKnPQTILMIMEEMYRtqrkrGNTSIVVHCSDTVGRSAMFCAAATTINKckteGvIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTY
  |    ....| ..||...      .  ..||||  |||.....||   . .    | .......|  | ..||.|.| .||. . ...| .
Dhgvpd.ldelldfieevle.....eggpvlVHCsaGvgRtgtlvaaylmkkl....g.vsleeavklvrsrRpgmvitpnqyfflqlallel

0049772 (Phosphotyrosine protein) phosphatases II 879-1043 8.9e-15 50.7 In-house 34-287 (314) alignment
Range on Protein: 879-1043
Range on HMM: 34-287/314.0
SEHSVTVGLSPSNKLLNRFANIVVYDeNRITLrPISGHKDCPneYINA----------------------------------------------------
.|....|.  . |.  ||. .|. .| ||  | |  .....   ||||                                                    
peltilvadlflnrdknryldilpad.nrvil.pglpvsgsd..yinasyvdgflkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivmsrd

--------------------------------------------CYVDRSVTQFQITNWDStGEVKNPQTILMIMEEMYRTqrkRGNTSIVVHCSDTVGR
                                             .. | . ..  ....  |..  .. .. ..| . .    . .. ..|||.. .||
evladelsrLdaAlgKtpllildgngneptaadlellkeelydpelferlgikylripvpD.gsaplledfdeflefieea...dkggpvlvHCkaGkgR

SAMFCAAATTINKCkteGViDVFQVLKSQRIQKP-----GSVQTVQQYQGIFQIVLTYLDSFETYS
.. |..||  . ..   || .. ..|.  | . |     |.... .||. |....| ||. .....
tgtfvvaaylmkll...gv.sleealedvrlkRpinpnpgfieqleqyefilealleylkflkkfy

subfamily_PTPN13_pd Subfamily PTPN13 931-1038 1.7e-14 48.8 In-house 166-271 (273) alignment
Range on Protein: 931-1038
Range on HMM: 166-271/273.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRkrGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQ
| |.... ..|   |  .... .| .. |. | |.   .. ||||||  .||| .. .  . ..  . .  .|| ..... | |. | ||| .||  ...
revahlnfvkwPdhgvPssaaellqfvaevrrlqt..dagPivvhcsaGiGrsGtlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvyk

IVLTYLDS
..|. | |
ailevlks

0051429 (Phosphotyrosine protein) phosphatases II 912-1039 3.5e-14 48.6 In-house 76-228 (272) alignment
Range on Protein: 912-1039
Range on HMM: 76-228/272.0
PISGHKDCPNEYIN-------------------------ACYVDRSVTQFQITNWDSTGEVKNPqtILMIMEEMYRtqrkrgNTSIVVHCSDTVGRSAMF
|| .. . . .|..                              | |.... |.|   |  ...  .| ..|.. .      .  ..||||  ..|....
pilddsaptilygalrvtllseellldyilrellltlllsagearevmhlhytdwpdhgvpqea..llellellld......ggpvlvHCsaGkdRTGtv

CAAATTINKCKTEGVID--------VFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYLDSF
.|.   .     | ..|        ......  | | ||.||| .||. .....| .|.|.
vallllllgvsletivddYlltnlyleeaveelraqrpgavqteeqylflyeallellrsl

subfamily_Choan-PTP-2_pd Subfamily Choan-PTP-2 931-1037 4.1e-14 47.2 In-house 152-265 (270) alignment
Range on Protein: 931-1037
Range on HMM: 152-265/270.0
RSVTQFQITNWDSTGEVKN------PQTILMIMEEMYRTQRKRGN-TSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQ
| .. |. ..|   | ...      .. .| ..... |....  . . ..||||. |||. .. |  ....  .... .|| ....  | ...  ||...
rrlvHfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcsaGvgRtGtlialDiavrlLeetkkvdvlaiieelRkdRmalvqhpe

QYQGIFQIVLTYLD
||. ... |..| .
qyeflykavveyae

fn3 Fibronectin type III domain 467-539 4.4e-14 45.6 Pfam-A 10-84 (85) alignment
Range on Protein: 467-539
Range on HMM: 10-84/85.0
ARTPTRINIVWNPPTIPNGIITVYEISYRESTSTS---PYNITNTTNtNYGIFGLIPNTSYTIGVRAYTSIGPGEW
..|.| ... |.||. ..| || ||. |||.....    .....||. .. . || |.|.|.. |.|..  | |..
evtstsltlsWsppkdgggpitgYeveyrekgggeewkeftvprttt.svtltgLkpgteYefrVqavngagegpe

subfamily_PTPRG_pd Subfamily PTPRG 847-930 7.2e-14 45.9 In-house 1-85 (563) alignment
Range on Protein: 847-930
Range on HMM: 1-85/563.0
IPVGQFGKFVANGHAKGKERFKTQFMMLDSGESEH--SVTVGLSPSNKLLNRFANIVVYDENRITLRPISGHKDCPnEYINACYVD
.|| .| | ||. ||.|. .|. .|  | |   ..   ..    |.||  ||  ||| ||. |..|.|..|.|.   .|||| |.|
vpvkefakhvaslhadgdigfseefealqsetiskdldaehsqkpenkrKnRylnivaydrsRvklsplpgkkkkl.DYinAnyid

I-set Immunoglobulin I-set domain 738-824 7.4e-14 43.3 Pfam-A 1-90 (90) alignment
Range on Protein: 738-824
Range on HMM: 1-90/90.0
PVIEEFPSNMTTEEGCQVLLKVKVKDTSKPSFNWYHNGELVTDDYAHELRGDG---SLLLVSVEEKHKGTYRFVANNDAGTVSQQVVLTV
|.... .......|| .| |...|. . .||..|...|. .. .  .... ..   .| . .||.. .|.|. .|.| ||...... |.|
pkftqklkdvevseGesvelectveGepepsvsWakdgselkssqrvkvtveeaeytLtIsnvevsDeGkYtckatnsagkaeakaeLkV

0049260 (Phosphotyrosine protein) phosphatases II 924-1029 4.9e-13 44.5 In-house 55-143 (152) alignment
Range on Protein: 924-1029
Range on HMM: 55-143/152.0
InacyvdrsvtQFQITNWDSTGEVKNPQTILMIMEEMYRTqRKRGNTSIVVHCSDTVGRSAMFCAAATTInkckteGVIDVFQVLKSQRIQKPGSVQTVQ
|          |.. ..|.  |  ...| .|.... . .  ... .  ..||||  |||.....||   .        ........  | ..||.|.. .
i..........qylhlpwpDhgvpdlsqlllflllfiekl.aldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpg

QYQGIF
|.. ..
qlrfly

0048076 (Phosphotyrosine protein) phosphatases II 928-1033 5.5e-13 44.3 In-house 42-140 (145) alignment
Range on Protein: 928-1033
Range on HMM: 42-140/145.0
YVDRSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRKrgNTSIVVHCSDTVGRSAMFCAAATTINkcktEGvIDVFQVLKSQRIQKPGSVQTVQQYQG
.. | ..|.. ..|.  |.   ....| ..| . . ...  .  ..||||  |||.....||   .     .| ......|.  | | ||.|....|.. 
llerlgiqylylpwpDhgvpdllellleflefieealke..ggpvlVHCsaGvgRtgtlvaaylmll....lg.vsleealelvrsqrpgavpnpgqlrf

IFQIVL
... .|
lyefel

subfamily_PTPN9_pd Subfamily PTPN9 931-1036 5.6e-13 43.6 In-house 173-290 (297) alignment
Range on Protein: 931-1036
Range on HMM: 173-290/297.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQR---------KR---GNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGS
|.|| ||.. |   |  .. ...| ..|.. ..|          ..    .  ||||||  .||.  |..   .... ...|..||....|  | |.  |
rkvthfqflsWPdyGvPssaaslldvlekvrekqalavkelgdewkghpsgPPivvhcsaGiGrtGtfitldiclsrleevgtvdvvetvkllrtqrafs

VQTVQQYQGIFQIVLTYL
.|| .||.  .. || | 
iqtpeqyefcylavleya

subfamily_Urchin-PTP-4_pd Subfamily Urchin-PTP-4 932-1037 6.5e-13 42.8 In-house 279-386 (392) alignment
Range on Protein: 932-1037
Range on HMM: 279-386/392.0
SVTQFQITNWDSTGEVKNP--QTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIF
.|||.|.  |   |  ...  ...| ..  .  .  .. . ||.|||    ||. .||.|   | .      .|.|| .|  | ..  .||| ..|  ..
tvtqyqfhgwpkhgsdqqsgarsllkliravkgstnskkefsilvhclsgagrtgvfctameciaqiaegdsvdifqtvkilradrmqfvqteeeyafvy

QIVLTYLD
...  || 
dvireylh

subfamily_Sponge-PTP9_pd Subfamily Sponge-PTP9 861-930 8.1e-13 42.7 In-house 11-79 (301) alignment
Range on Protein: 861-930
Range on HMM: 11-79/301.0
AKGKERFKTQFMMLDSGESeHSVTVGLSPSNKLLNRFANIVVYDENRITLRPISGHKDCPNEYINACYVD
|| ...|. |.  |..||. .| ||||| .|| |||| ||.|||.|||.|.| .  . | .||||| |.|
akhsnkfeeqykelkeged.ksctvglseenkalnrfknitvyddnriilkpkpnldlcqreyinasyid

0046846 (Phosphotyrosine protein) phosphatases II 934-1037 1.8e-12 42.8 In-house 77-174 (176) alignment
Range on Protein: 934-1037
Range on HMM: 77-174/176.0
TQFQITNWDSTGEVKNpQTILMIMEEMYRTQRKRgnTSIVVHCSDTVGRSAMFCAAAttinKCKTEGVIDVFQVLKSQRIQKP-GSVQTVQQYQGIFQIV
 |.. ..|.  |     . .| ..|.... ...     ..||||  .||.....||      ...|  ..|...|.  | |.| |.||| .||. . . .
iqylhlpwpDhgvpdl.elllellefirealkeg..gpvlVHCsaGigRtgtlvaay....llelekglsveealalvreqRplgavqtpeQyrflyefe

LTYLD
| .|.
llllk

subfamily_PTPRN_pd Subfamily PTPRN 931-1032 2.4e-12 41.2 In-house 187-288 (297) alignment
Range on Protein: 931-1032
Range on HMM: 187-288/297.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRKRGnTSIVVHCSDTVGRSAMFCAAATTINKC-KTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIF
|.||||    | ..|   .....|     . .. | |  ..||||||| .||. ....    .|.  |    ||.   |.  | |.|| |.| .|.. ..
rtvtqfhflswpeegvPasaksllefrrkvnksyrGrs.cpivvhcsdGaGrtGvyilidlvlnrllkGvkeidiaatlehlrdqrpglvktkdqfefal

QIV
. |
tav

subfamily_PTPN14_pd Subfamily PTPN14 930-1037 2.6e-12 41.3 In-house 182-297 (300) alignment
Range on Protein: 930-1037
Range on HMM: 182-297/300.0
DRSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRKRGNT--------SIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQT
.|.|  .| |.|   |  ..... |  .||.   .||  ..         ..||||. |||. .   .   |.  ... .||. .||.  | |.   |||
ertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseveskeskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLreqrmllvqt

VQQYQGIFQIVLTYLD
. ||. .......||.
laqYkfvYkvlikylk

0048179 (Phosphotyrosine protein) phosphatases II 927-1029 3.1e-12 41.9 In-house 43-138 (144) alignment
Range on Protein: 927-1029
Range on HMM: 43-138/144.0
CYVDRSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRkrGNTSIVVHCSDTVGRSAMFCAAATTInkckTEGvIDVFQVLKSQRIQKPGSVQTVQQYQ
 .. | ..|.. ..|.  |    .. .| ..| . . ..   .  ..||||  |||.....||   .    ..| ......|.  | . ||.|.. .|..
efleregiqylhlpwpDhgvpdllellleflefieeale..eggpvlVHCsaGvgRtgtlvaaylmk....klg.lsleealalvrsrrpgavpnpgqlr

GIF
 . 
fLl

subfamily_PTPN3_pd Subfamily PTPN3 930-1033 3.9e-12 40.7 In-house 170-272 (280) alignment
Range on Protein: 930-1033
Range on HMM: 170-272/280.0
DRSVTQFQITNWDSTGEVKNPQTILMIMEEMyRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIF
.|...|.| ..|   |  .... .| ..|.. |..|.  .. .|||||  .||. .. .  |.. .  ..  . . ....  | |.   |||..||. . 
erkilqlqylaWpdhgvPddsadflefverv.rklrsgkeePvvvhCsaGigrtGvlilletalalieaaepvypldivrtmrdqramlvqtasqykfvC

QIVL
. .|
eail

subfamily_Anemone-PTP-6_pd Subfamily Anemone-PTP-6 847-930 1.1e-11 39.4 In-house 2-83 (318) alignment
Range on Protein: 847-930
Range on HMM: 2-83/318.0
IPVGQFGKFVANGHAKGKERFKTQFMMLDSGESEHSVTVGLSPSNKLLNRFANIVVYDENRITLRPISGHKDcpNEYINACYVD
|.| .. . |.. ...|.  ..... .|.  |.. . .  |.| ||  ||.|||. ||. |. |....|...   .|||| |.|
isvedleshvrrlresGelllseeyerlsrseetvtslkslepvnkaknryanilaydhtrvkLqmlegeeg..sDyinanyid

subfamily_Anemone-PTP-5_pd Subfamily Anemone-PTP-5 846-930 2.9e-11 38.0 In-house 4-85 (319) alignment
Range on Protein: 846-930
Range on HMM: 4-85/319.0
LIPVGQFGKFVANGHAKGKERFKTQFMMLDSGESEhSVTVGLSPSNKLLNRFANIVVYDENRITLRPISGHKDcpNEYINACYVD
 |.| .. . . . ...|.  .. .|..|. .... ...    . ||  ||. ||. ||  |..| .. | ..   .|||| ..|
eievqeLkerlkalastgetllekefkllkeavnd.tfdsaskeenkkknryqnilaydrtrvvlseldgveg..sdyinasfid

0051082 (Phosphotyrosine protein) phosphatases II 930-1030 2.9e-11 38.7 In-house 57-147 (151) alignment
Range on Protein: 930-1030
Range on HMM: 57-147/151.0
DRSVTQFQITNWDSTGEVKNPQTILMIMEEMYRtqrkRGNTSIVVHCSDTVGRSAMFCAAATTINKcktegvIDVFQVLKSQRIQKPGSVQTVQQYQGIF
.. |....|..|. .|   .....| ..|.. .     .|  ..||||  .||.....|.   . .      ......|.  |.. ||.||. ||.. ..
gievlhipildwpdpglplsfdavleflellld....kkngpvlvHCsaGkgRTGtlvalylmllg......vsleealeeyrlkrpgvvqpnqqflfql

Q
.
f

subfamily_Urchin-PTPRB-like_pd Subfamily Urchin-PTPRB-like 855-930 1.2e-10 35.9 In-house 11-84 (288) alignment
Range on Protein: 855-930
Range on HMM: 11-84/288.0
FVANGHAKGKERFKTQFMMLDSGESEHSVTVGLSPSNKLLNRFANIVVYDENRITLRPISGHKDcpNEYINACYVD
 ||. .|.... |. ..  | . |...|||.|  . |.  ||. ||. |||.|. |.     ..  ..|||| |.|
kvakksarnrtgfseeynsLaalektksvtagrlavnakknRyrnilpyDekrvklkkleeeag..aDYinasyid

subfamily_Nvec-PTP-1_pd Subfamily Nvec-PTP-1 930-1033 1.7e-10 35.5 In-house 135-237 (239) alignment
Range on Protein: 930-1033
Range on HMM: 135-237/239.0
DRSVTQFQITNWDSTGEVKNPQTILMIMEEMYRtQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIF
.| | |...| |   |  .   ..| .  .. . .   |    |.|||  |||.  |    . . ..| .  .|.|. .|. | ..|  ||| .||  |.
eryvyqyhftvwpdkgvpqyatavlglrrkitk.dslpgarpwvihcsagvgrtgaflvidamlrqakkqktvdifnyvkairedrphmvqtseqyvfih

QIVL
  ||
lavl

subfamily_Anemone-PTP-1_pd Subfamily Anemone-PTP-1 930-1033 1.8e-10 35.4 In-house 136-238 (239) alignment
Range on Protein: 930-1033
Range on HMM: 136-238/239.0
DRSVTQFQITNWDSTGEVKNPQTILMIMEEMYRtQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIF
.| | |...| |   |  .   ..| .  .. . .   |    |.|||  |||.  |    . . ..| .  .|.|. .|. | ..|  ||| .||  |.
eryvyqyhftvwpdkgvpqyatavlglrrkitk.dslpgarpwvihcsagvgrtgaflvidamlrqakkqktvdifnyvkairedrphmvqtseqyvfih

QIVL
  ||
lavl

subfamily_PTPRB_pd Subfamily PTPRB 845-930 2e-10 35.2 In-house 5-88 (293) alignment
Range on Protein: 845-930
Range on HMM: 5-88/293.0
NLIPVGQFGKFVANGHAKGKERFKTQFMMLDSGESEHSVTVGLSPSNKLLNRFANIVVYDENRITLRPISGHKDcpNEYINACYVD
. | . .| ..|.. .|. . ||. .. .| . .....|..  .. |.  ||. ||. ||..|. | .......  ..|||| |..
kpiklekfeehvkkmkadsdlrfseeyeelkavgkdqavkaaelavnraknrytnilpydhsrvkLaalkdesg..sDYinanyip

subfamily_Anemone-PTP-2_pd Subfamily Anemone-PTP-2 852-930 2e-10 35.4 In-house 14-93 (298) alignment
Range on Protein: 852-930
Range on HMM: 14-93/298.0
FGKFVANGHAKGKERFKTQFMMLDSGES---EHSVTVGLSPSNKLLNRFANIVVYDENRITLRPISGHKDCpnEYINACYVD
. |..|  ..|.  .....|  |.|..|   |.. .|. .|.||  ||.|.|. .|  |. |. ... ...  .|||| ...
lqklaavkkkkkltgyalefqrlnsvsseieeeekevarkpenkkkNRyadiialdssRvvLekedadees..dYiNAsflh

subfamily_Choan-PTP-4_pd Subfamily Choan-PTP-4 956-1035 2.4e-10 34.8 In-house 216-294 (297) alignment
Range on Protein: 956-1035
Range on HMM: 216-294/297.0
IMEEMYRTQRKRgNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTY
.  | .|..  | |. ..||||  |||| .   . . ..| . . . ||  .|.  | |..  |||..|.. ....||  
lqleslraempr.nayllvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqtleqfellydavlkk

subfamily_Anemone-PTP-4_pd Subfamily Anemone-PTP-4 931-1033 2.8e-10 34.8 In-house 133-236 (237) alignment
Range on Protein: 931-1033
Range on HMM: 133-236/237.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRKR-GNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIF
| . |.|.| |   |  ..  ..| .  ..    ..    .  ..|||  |||...|    . . ..| . |.|... ..|   ..|  .|| .||  |.
rlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlrqakekkvvdiynyvysieedrpyiiqtkdqyvfih

QIVL
| .|
qtil

subfamily_Cele-PTP-6_pd Subfamily Cele-PTP-6 930-1043 3.1e-10 34.5 In-house 175-286 (307) alignment
Range on Protein: 930-1043
Range on HMM: 175-286/307.0
DRSVTQFQITNWDSTGEvknPQTILMIMEEMYRTqRKRgNTSIVVHCSDTVGRSAMFCAAATTINKC-KTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGI
 |.....| .||   |    ||. |  .. .  . |   .  .|||||  ||||    | .   .|  . .   |. ....  | |.. ..||  ||  .
srtiqhlqwenwpdrgv...pqinltainlleav.ryd.tnpvvvhcsaGvGrsGtivaislvqdkmiaGinckdmkklveelrsqrhyaiqteaqylyl

FQIVLTYL-DSF-ETYS
 ...| |. . . ||| 
hrvlleyflelyketye

subfamily_PTPN1_pd Subfamily PTPN1 931-1031 4.6e-10 33.7 In-house 162-266 (290) alignment
Range on Protein: 931-1031
Range on HMM: 162-266/290.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQR-KRGNTSIVVHCSDTVGRSAMFCAAATTIN---KCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQ
|....|  | |   |  . |.. |  . .. ..   ..     |.|||  .|||  || . | .    | .    .|. .||   | .. | .|| .| .
reilhfhyttwpdfgvpespaaflkflfkvresGslssdvGpavihcsaGiGrsGtfclvdtclvliekkddlssvdikkvllelrkyrlGliqtadqlr

GIFQI
  .. 
fsyla

subfamily_Cele-PTP-4_pd Subfamily Cele-PTP-4 938-1036 1.4e-09 31.8 In-house 188-285 (302) alignment
Range on Protein: 938-1036
Range on HMM: 188-285/302.0
ITNWDSTGEVKNPQTILMIMEEMYRTQrKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYL
.||| ..   ..  ..   .....  .   .. ..|.     .|| ..| ..|....| ...    . ...|| | |.| .|....||  .. ..|.|.
ltnWkqkkvpvkyaeliktaakvfakk.ikadentvivSknGaGRagafltlavaveklqkgkepnikeivksiRsqRpravdslkQyvslyialllyi

0044763 (Phosphotyrosine protein) phosphatases II 928-1032 3.1e-09 32.2 In-house 70-167 (178) alignment
Range on Protein: 928-1032
Range on HMM: 70-167/178.0
YVDRSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRkRGNTSIVVHCSDTVGRSAMFCAAATTINKckteGViDVFQVLKSQRIQKPgSVQTVQQYQG
....   |.. ....  |.   .. .| ..| . . .  . .  ..||||  ||||....||   .      |. .......  | ..|  |..  |.. 
wpeeagiqylhipipDhgvpdllehflefvefieeald.ekggpvlVHCsaGvgRsgtlvaaylmkkl....gl.sleeaielvrerRp.ivpnpgqlrq

IFQIV
. .. 
Lyefe

subfamily_Sponge-PTP8_pd Subfamily Sponge-PTP8 846-930 3.2e-09 31.4 In-house 3-83 (305) alignment
Range on Protein: 846-930
Range on HMM: 3-83/305.0
LIPVGQFGKFVANGHAKGKERFKTQFMMLDSGesEHSVTVGLSPSNKLLNRFANIVVYDENRITLRPISGHKdcPNEYINACYVD
 | . .. ... . ... .. ...|. .| .   |.|. || .  ||  ||...|...|..|| |.. . ..   ..||||.|||
iialddlaayikearvysdkgleaqykslyee..eesidvgkkeankaknrlkeitlldddriiltekesld..dsdyinasyvd

subfamily_Sponge-PTP6_pd Subfamily Sponge-PTP6 930-1034 5.3e-09 30.0 In-house 173-277 (439) alignment
Range on Protein: 930-1034
Range on HMM: 173-277/439.0
DRSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIF
.|.| ||. . |       .   .|  .  .  .. |.    .|||||  |||.    |   .... |.|  .|.  ..|  | |.   ||.. ||  |.
ertvlqfhyiawpdknvpaqashvldflrainsandkeeygpvvvhcsagvGrtGtiialdialeqlklenkvdikgivkvlrkqrkqmvqalcqyvfiy

QIVLT
. || 
navle

subfamily_Cele-PTP-7_pd Subfamily Cele-PTP-7 929-1029 6.3e-09 29.7 In-house 186-281 (302) alignment
Range on Protein: 929-1029
Range on HMM: 186-281/302.0
VDRSVTQFQITNWDSTGEVKNPQTILMIMEemYRTQRKrgnTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGI
| ..|  .. . |   |  |...| | |.   .    |   ....||||  |||.  . |    |. |... | |. ....  |  . |.||. ||   .
vkktvdilafsawpdhGapkeaytaldilk..fcesyk...knvlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqdeqqliyl

F
.
l

subfamily_Ptp69D_pd Subfamily Ptp69D 856-929 6.6e-09 30.3 In-house 13-84 (307) alignment
Range on Protein: 856-929
Range on HMM: 13-84/307.0
VANGHAKGKERFKTQFMMLDSGESEHSVTVGLSPSNKLLNRFANIVVYDENRITLRPISGHKDCpnEYINACYV
. . . . .. ..  . .| . |...| .|.    |.| ||. .|. .|..|. |..| |..|   .|||| ..
lksrkrdtdfglakeyekLeareidkstkvsekkenalknRyedikafDktRvkLkkingkeds..dYinasfi

subfamily_Cele-PTP-19_pd Subfamily Cele-PTP-19 928-1025 1e-08 29.3 In-house 178-270 (301) alignment
Range on Protein: 928-1025
Range on HMM: 178-270/301.0
YVDRSVTQFQITNWDSTGEVKNPQTILMIMEeMYrtqrKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQY
.  |.|| .| ..|   |  |    .  .|| .     |. .  ||||||. .|||  | ..    .. ...  |.. . ||  | ..  .|||..| 
fatrtvthyqysewtdrgvPkshaelfdlme.lv....kksekPivvhcsaGiGrsvafigteylareveadptieltealkhlrehrwngvqtnsql

DSPc_SM00195 867-930 1.1e-08 30.1 In-house 2-63 (263) alignment
Range on Protein: 867-930
Range on HMM: 2-63/263.0
FKTQFMMLDSGESEHSVTVGLSPSNKLLNRFANIVVYDENRITLRPISGHkdCPNEYINACYVD
.|..|  |.. .|....| .  ..||  ||. ||..||..|. | .. ..   ...|||| |..
lkeefekleestspketteaekkknksknRyknilpydhtrVklkkeekk..egsdYINAnyik

PTPc_SM00194 867-930 1.1e-08 30.1 In-house 2-63 (263) alignment
Range on Protein: 867-930
Range on HMM: 2-63/263.0
FKTQFMMLDSGESEHSVTVGLSPSNKLLNRFANIVVYDENRITLRPISGHkdCPNEYINACYVD
.|..|  |.. .|....| .  ..||  ||. ||..||..|. | .. ..   ...|||| |..
lkeefekleestspketteaekkknksknRyknilpydhtrVklkkeekk..egsdYINAnyik

subfamily_CG42327_pd Subfamily CG42327 963-1035 2e-08 28.3 In-house 241-314 (319) alignment
Range on Protein: 963-1035
Range on HMM: 241-314/319.0
TQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTE-GVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTY
. ..  .  .|||||| |||. .  |.  .|.. ..    .|. |.. | | ..  .|.|..||. |....  |
sgtresqGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefiykvlsey

subfamily_Cele-PTP-8_pd Subfamily Cele-PTP-8 934-1036 2.1e-08 28.5 In-house 174-271 (288) alignment
Range on Protein: 934-1036
Range on HMM: 174-271/288.0
TQFQITNWDSTGEVKNPQTILMIMEEMyrtqrKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVL
 .  . .||  |  .| .. | ..| .     |  .  ||||.|  |||.. .      ..  . .  . . ..|.. | ..  ..|| .||  ....||
kilhlleWdddgvPenylsplrllevl.....kslqkPivvhssaGvGrtgtlililialeslrlddflgirsllaklreerfkaiqtemqylyvhrcvl

TYL
 .|
eel

subfamily_Choan-PTP-3_pd Subfamily Choan-PTP-3 932-1037 2.4e-08 28.1 In-house 169-278 (287) alignment
Range on Protein: 932-1037
Range on HMM: 169-278/287.0
SVTQFQITNWdsTGEVKNPQ---TILMIMEE--MYRTQRK-RGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQY
 | |... .|    .|  |     | ....       .|.  .   .|||..  .||| .. |  . ... .  | .|| .|.   | .. . ||.| |.
vvkqldllsw..PdkvlaPtavglirfvldvkqhielardasevGPlvvhddvGiGrsGillatlvlvsrledlGrvdvaavvirlreyraalvqavvql

QGIFQIVLTYLD
. ... . ||  
rllyealvtyyk

subfamily_Choan-PTP-1_pd Subfamily Choan-PTP-1 862-930 2.9e-08 28.2 In-house 12-78 (281) alignment
Range on Protein: 862-930
Range on HMM: 12-78/281.0
KGKERFKTQFMMLDSGESEHSVTVGLSPSNKLLNRFANIVVYDENRITLRPISGHKdcPNEYINACYVD
. .. |....  | . . ... |   .. |.| ||. ||| ||  |... | . .|   ..|||| .|.
ndnaGfieeyeklaaigvdntataskadenvlknrYsnivaYDatrvkvtpneenk..ntDYinanfvp

subfamily_Sponge-PTP3_pd Subfamily Sponge-PTP3 848-931 6.4e-08 26.7 In-house 6-83 (95) alignment
Range on Protein: 848-931
Range on HMM: 6-83/95.0
PVGQFGKFVANGHAKGKERFKTQFMMLDSgESEHSVTVGLSPSNKLLNRFANIVVYDENRITLrpiSGHKDcpNEYINACYVDR
 |  |   | . |..  . |  .|  .    |  . ||| | .|   ||| ||. ||  |..|   . ..|   .|||||.|| 
hvsvfhshvlemhsnsdqefdnefksism.tsgapytvgsseanipknrflnifpydatrvvl...ttkrd..sdyinacfvdg

subfamily_Cele-PTP-13_pd Subfamily Cele-PTP-13 955-1035 7.4e-08 26.4 In-house 187-268 (281) alignment
Range on Protein: 955-1035
Range on HMM: 187-268/281.0
MIMEEMYRTQRKRgNTSIVVHCSDTVGRSAMFCAAATTINKCKTEG-VIDVFQVLKSQRIQ-KPGSVQTVQQYQGIFQIVLTY
 .| .. |  | |  |  |.|||  ||||  . |   ...  ..   . |. |..   |.  .  ||||.|||  |....| .
evmlkilrkirar.stppvihcsagvgrsgtlmaveialqsihshftlpdikqivshlrvtgraasvqtlqqymliwkvlldf

subfamily_PTPN6_pd Subfamily PTPN6 858-933 9.2e-08 26.4 In-house 19-93 (306) alignment
Range on Protein: 858-933
Range on HMM: 19-93/306.0
NGHAKGKERFKTQFMMLDSGESEH--SVTVGLSPSNKLLNRFANIVVYDENRITLRpisGHKDCPNEYINACYVDRSV
... ..|. |. .|  |.  |...  | . |  |.||  ||. ||. .|..|..|.    ..   ..|||| |....|
eeeslekagfeeefeelqqeeakkllsrkegakpenkeknryknilPfDhtrvilk...epsvpgsdyinanyikkev

subfamily_Cele-PTP-18_pd Subfamily Cele-PTP-18 932-1037 1.9e-07 25.1 In-house 187-288 (305) alignment
Range on Protein: 932-1037
Range on HMM: 187-288/305.0
SVTQFQITNWDSTGEvknPQTILMIMEEMYRTQRKRGntSIVVHCSDTVGRSAMFCAAATTINKCKTEGVID-VFQVLKSQRIQKPGSVQTVQQYQGIFQ
 ||..   .|   |    | . | |.| . ...  .|   ||||||  .||.         ...  .  .|.   ..|.  | |.  |.|| .||  . |
kvthyhwidwpdrgv...paadlailellekarpskg..pivvhcsagigrtgsvvmleyildqllagqiiedtdkilqkireqrnnsiqtdaqylfvhq

IVLTYLD
..| |. 
vilnyfr

subfamily_Cele-PTP-5_pd Subfamily Cele-PTP-5 951-1036 2.1e-07 23.9 In-house 223-309 (346) alignment
Range on Protein: 951-1036
Range on HMM: 223-309/346.0
QTILMI-MEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYL
.|. .| |   . ....  |. . |      ||.  |  |  .||.       ......|. . |.||.|..  || .|. ||. |.
ktlpiikmihqflsekqvqnagvcvvslfgcgracsfigalyainqlnngiepniceimknikqqrpggvesfaqyasiyaivfdyi

subfamily_Cele-PTP-20_pd Subfamily Cele-PTP-20 954-1039 2.1e-07 24.9 In-house 203-286 (290) alignment
Range on Protein: 954-1039
Range on HMM: 203-286/290.0
LMIMEeMYRTQRKRgNTSIVVHCSDTVGRSAMFCAAATTInKCKTEG-VIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYLDSF
| ..  . |. ||  .  .|||||  .||.  | |  ... .. ..|  .|. .. .. |  . .|||   ||  . .|.| .  .|
lallr.tlrilrka.sGpvvvhcsaGiGrtGtfvaievgl.qilldGkeldlldlvralrnsrlnsvqvdiqylalveilldlGkdf

subfamily_Urchin-PTP-7_pd Subfamily Urchin-PTP-7 846-930 2.2e-07 25.1 In-house 5-86 (315) alignment
Range on Protein: 846-930
Range on HMM: 5-86/315.0
LIPVGQFGKFVANGHAKGKERFKTQFMMLDSGEsEHSVTVGLSPSNKLLNRFANIVVYDENRITLrPISgHKDCPNEYINACYVD
 ||. |.  .||. .|  |. || ..  .  |.  | . |     ||  ||. ||. ||. |. | |.   .|   .|.|| ..|
pipldqlityvaqkkastkngfkqdyesipggq.lhpldvakkienkqknryiniiaydksrvql.pll.endphsdyvnanfid

subfamily_PTPRA_pd Subfamily PTPRA 845-930 2.8e-07 24.7 In-house 12-95 (330) alignment
Range on Protein: 845-930
Range on HMM: 12-95/330.0
NLIPVGQFGKFVANGHAKGKERFKTQFMMLDSGESEHSVTVGLSPSNKLLNRFANIVVYDENRITLRPISGHKDcpNEYINACYVD
  .|| .. . .    |   ..|. .|  | .|. . .. .     ||  ||. ||. || .|. | ...|...   .|||| ..|
fplpvekleeeirirsaddnklfreefnalPagpiqatlelaskeenkeknrvvnilPydfsrvilsvkeGvee..sdyinasfid

subfamily_Nvec-PTP-3_pd Subfamily Nvec-PTP-3 928-1031 3.4e-07 24.6 In-house 91-198 (198) alignment
Range on Protein: 928-1031
Range on HMM: 91-198/198.0
YVDRSVTQFQITNWD--STGEVKNPQTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTIN---KCKTeGVIDVFQVLKSQRIQKPGSVQTV
   | ....|.| |   .| .|     ...   |. .   .  .. ..|||||  | . .| |    .    . ||  |.|.|.| |  |  . | . ..
pstreishyqftswkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheeskt.svvdlfevakrlrqarcgiissl

QQYQGIFQI
|.|. |.|.
qhynfiyqv

subfamily_Anemone-PTP-3_pd Subfamily Anemone-PTP-3 928-1031 3.5e-07 24.6 In-house 92-199 (199) alignment
Range on Protein: 928-1031
Range on HMM: 92-199/199.0
YVDRSVTQFQITNWD--STGEVKNPQTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTIN---KCKTeGVIDVFQVLKSQRIQKPGSVQTV
   | ....|.| |   .| .|     ...   |. .   .  .. ..|||||  | . .| |    .    . ||  |.|.|.| |  |  . | . ..
pstreishyqftswkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheeskt.svvdlfevakrlrqarcgiissl

QQYQGIFQI
|.|. |.|.
qhynfiyqv

subfamily_Urchin-PTP-3_pd Subfamily Urchin-PTP-3 854-929 4.8e-07 24.2 In-house 12-84 (325) alignment
Range on Protein: 854-929
Range on HMM: 12-84/325.0
KFVANGHAKGKERFKTQFMMLDSGESeHSVTVGLSPSNKLLNRFANIVVYDENRITLRPIsgHKDCPNEYINACYV
..| . .|. .. |  .| .| | ..  . .|   | ||  ||| |.| .|..|. |     ..|   .|||| |.
ehvekkkaqdqdgfahefgllpsddg.iakkvamkpenkaknrfknvvaldksrvvletk..kddpssdyinasyl

Ig_3 Immunoglobulin domain 737-811 6.1e-07 21.6 Pfam-A 1-75 (75) alignment
Range on Protein: 737-811
Range on HMM: 1-75/75.0
KPVIEEFPSNMTTEEGCqVLLKVKVKDTS-KPSFNWYHNGELVTDDYAHELRGDGSLLLVSVEEKHKGTYRFVANN
||||   ||...|..|  | |   ..... .|.. ||  .. . .       ....| . || ... |||. ||.|
kPvisvspsptvtsggn.vtLtCsaeggpppptisWyietppelqgsegssssestLtissvtsedsGtYtCvasN

Ig_2 Immunoglobulin domain 737-824 7.2e-07 21.2 Pfam-A 1-80 (80) alignment
Range on Protein: 737-824
Range on HMM: 1-80/80.0
KPVIEEFPSNmtTEEGCQVLLKVKVKDTSKPSFNWYHNGELVTDDYAHelrgdgsLLLVSVEEKHKGTYRFVANND-AGTVSQQVVLTV
|||... |..   .||..| |  ....  .|.. ||..||...   .        |.. .|.....|||. .| |.  ...|. | .||
kpvlsapptv..vtegenvtLtCqapgnptpkvqwykdgeelsqsqna.......lfipnvsaedsGtYtCrasnsegskqsnsvevtv

subfamily_Fungi-PTP1_pd Subfamily Fungi-PTP1 933-994 1.7e-06 22.0 In-house 217-287 (350) alignment
Range on Protein: 933-994
Range on HMM: 217-287/350.0
VTQFQITNWDSTGEVKNPQTILMIME--------EMYR--TQRKRGnTSIVVHCSDTVGRSAMFCAAATTIN
| |.|. ||   . . ||. || ..|         . .   . .|. ..|.||||  |||  ....    ..
vyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnars.spilvhCsaGvGrtGtlvtlDslls

subfamily_Nvec-PTP-2_pd Subfamily Nvec-PTP-2 885-930 1.8e-06 22.3 In-house 3-46 (250) alignment
Range on Protein: 885-930
Range on HMM: 3-46/250.0
VGLSPSNKLLNRFANIVVYDENRITLRPISGHKDCpnEYINACYVD
|.  |.||  ||.|.|. .|. |. | . .| |..  .|||| ...
vakkpqnkeknryadiialdssrvvLekekgdkes..dyinasflh

subfamily_Cele-PTP-10_pd Subfamily Cele-PTP-10 931-1036 2.3e-06 21.5 In-house 188-289 (305) alignment
Range on Protein: 931-1036
Range on HMM: 188-289/305.0
RSVTQFQITNWDSTGEvknPQTILMIMEEMYRTqRkRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTE-GVIDVFQVLKSQRIQKPGSVQTVQQYQGIF
 || ..| |.|   |    |   |  .| .    |   .  ||||||  .||.    |    ..|   .  .  . ...|. | |.  |.|.  ||  | 
msvrhlqwtewpdrgv...ppckltslellsai.r.gskvpivvhcsagigrtgtivaieyilekiaenkpcppmpelvkalrdqrafsiqndvqylfih

QIVLTYL
...| |.
rvmlnyf

subfamily_Cele-PTP-1_pd Subfamily Cele-PTP-1 932-1033 2.6e-06 21.8 In-house 159-256 (290) alignment
Range on Protein: 932-1033
Range on HMM: 159-256/290.0
SVTQFQITNWDSTGEVKNPQTILMIMEEMyrtqrKRGNTSIVVHCSDTVGRSAMFCAAATTINKCK-TEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQ
 ||  .. .|...   ....|.| ... .     |  .| ..||| | . |||.. |      |   |.| . . .|||. | |.   ... ...  .  
tvtHsllkgWnklnvqedtktllsliqkv.....kasktpvivHcvdGiSrsAalaaiilgyQkiaetsgsvkledvlkalrkqralaitsalelafvda

IVL
 ..
giv

subfamily_PTPN14_pd Subfamily PTPN14 881-935 2.7e-06 21.6 In-house 39-90 (300) alignment
Range on Protein: 881-935
Range on HMM: 39-90/300.0
HSVTVGLSPSNKLLNRFANIVVYDENRITLRPisgHKDCPNEYINACYVDRSVTQ
  ....  | |.  ||| ... |..||. | |    |.  ..||||  .  ||. 
allstaklpenaeknrfkdvlPyednrvelsp...tkenstgyinassikvsvgg

subfamily_Urchin-PTP-4_pd Subfamily Urchin-PTP-4 846-930 4.1e-06 20.5 In-house 3-82 (392) alignment
Range on Protein: 846-930
Range on HMM: 3-82/392.0
LIPVGQFGKFVANGHAkgKERFKTQFMMLDSGEsEHSVTVGLSPSNKLLNRFANIVVYDENRITLRPISGHKDcpNEYINACYVD
 ||| ||  || . .      |  .|  | . .  .  ||.  . |.  ||. ||. ||..|. |  |    |  ..|.|| |..
pipvaqfpafveknrh..salffeefhdlpgpd.iypqtvaqkeinlkknryknilpydsarvkleviddipd..sdylnasyip

subfamily_PTPN23_pd Subfamily PTPN23 860-931 4.6e-06 20.7 In-house 10-77 (288) alignment
Range on Protein: 860-931
Range on HMM: 10-77/288.0
HAKGKERFKTQFMMLDSGESEHS--VTVGLSPSNKLLNRFANIVVYDENRITLRpisGHKDcpnEYINACYVDR
  .||  ....|  |.. . ...   .. ..  .   ||. .|. ||.||..||   |.||   .||||..|  
mldgktaldkkfkeleqkqdkearkrsiaiaklyseknrsrdilPyDhnRvklr...gskD...DYinAsfvkd

subfamily_Urchin-PTP-1_pd Subfamily Urchin-PTP-1 847-929 5.1e-06 20.6 In-house 3-80 (315) alignment
Range on Protein: 847-929
Range on HMM: 3-80/315.0
IPVGQFGKFVANGhaKGKERFKTQFMMLDSGEsEHSVTVGLSPSNKLLNRFANIVVYDENRITLRPISGHKDcpNEYINACYV
||| ||  || .   .    |  .|  |   .  .  .|.  . |   ||. ||. .|..|. |  |  . |  ..|||| |.
ipvaqfpafvnkn..rhtalfseefhdlpdPd.iyrqrvaretinfkknryknilPldsarvkleviddsPd..sdyinasyi

subfamily_hpo-7_pd Subfamily hpo-7 932-1035 8e-06 19.9 In-house 123-226 (263) alignment
Range on Protein: 932-1035
Range on HMM: 123-226/263.0
SVTQFQITNWDSTGEVKNPQTILMIMEemyrTQrkRGNTSIVVHCSDTVGRSAMFCAAATTIN-------KCKTeGVIDVFQVLKSQRIQKPGSVQTVQQ
 |.... . |  . ...... || |..        |.  |.|||||  .|||| |  | .          . .| . .|  ..|.  | .......|  |
tvkhysykgWiekndpelareilnilk....va..rnskslvvhcstGiGrsaafsvaElvyqkmirsldttst.veldylsLleelrssrkraihtPmq

YQGIFQIVLTY
    . .||..
LafsilmvLdf