Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 249-519 | 3.7e-139 | 457.4 | In-house | 1-283 (283) | alignment | ||
Range on Protein: 249-519
Range on HMM: 1-283/283.0
DNASVTGFEAQFNVLEQVSVPPQDAVCDVARQHPRKNRYQEILPTDQWRVHLKSESPDYINAVFIP---SYKNDKGFIIAQSPLRETRRDFWKMIFDREI
||..|........||...|||..||....|....||||.|||.|.|||||.|||||.||||||||| |||.||..|||||||..|..|||||.||..|
dnlrvnnnklfrevlkrlsvpdldadiasadenkrknrnqeivpadqwrvelksesrdyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdeki
TTIVMLSPIMEGEEEACAQYWPKEGTIEFGEFTISVREEWGHQSFSRKLLLIRNN---KNNMLrrLAHFQVDGWsnddiTSCNEGAIINTM---NLVKTL
|.||||....|.....|.|||||.|....||||...|.|....||..|.||.|.| |...| |||.||..| ....|.||||.. |.|..|
taivmltklqedlrikCsqyWPkrGsedyGeftvtlrkettsnsfiikelllrvnssakstll..lahyqvidW.....leygeqaiinslvkfnkvisl
QRKSPNSPILMHCSNMIGRSAVFCAAMATVDQMKSSSVVDVFQTVKNMRVNLPGAVQNKGQYKMIHTLA----------AAYVNLFSTSA
|..|...||..|||..|||.|||.||.|.|......||||||..||.||.....|||...|||..|.|. .|.|.|.||.|
qteskkgPivvhCstgiGrtavfiaasasvkdaltesvvdvfavvkimreqrmmavqtldqyklvhelvleqalcgdtqiaavdlqstia
|
|||||||||
subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 1-243 | 9.5e-136 | 446.2 | In-house | 66-283 (283) | alignment | ||
Range on Protein: 1-243
Range on HMM: 66-283/283.0
MVNKDDEQSQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSRGSEDYGPFTVTLQKETTSNSFIIRELTLHYNtmmgnlrski
.|.|...|..|||..|.||||||||||.||..||..|||||||||||||||||||||.|||||||.|||||.||||||||||.||.|..|
pvsksykqdkkyiiaqsPldrtvvdfWkmvfdekitaivmltklqedlrikCsqyWPkrGsedyGeftvtlrkettsnsfiikelllrvn..........
vnptgridpnkkeyySSAQSTLLITHYQFIDWLEYGPQPPINSLVKFNKIISNQTEHKKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTI
|||.||||..|||.|||||||.|..|||||||||.||.|||.||||||||||||.|||..||..|.|.|||||||..|..|||.|
...............ssakstlllahyqvidWleygeqaiinslvkfnkvislqteskkgPivvhCstgiGrtavfiaasasvkdaltesvvdvfavvki
MREQRMMMIQTLDQYMLVHEAVLEQALCGDTQIVACDLQNTIS
|||||||..||||||.||||.||||||||||||.|.|||.||.
mreqrmmavqtldqyklvhelvleqalcgdtqiaavdlqstia
|
|||||||||
subfamily_PTPRD_pd | Subfamily PTPRD | 8-302 | 1.3e-81 | 269.9 | In-house | 89-359 (564) | alignment | ||
Range on Protein: 8-302
Range on HMM: 89-359/564.0
QSQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSRGSEDYGPFTVTLQKETTSNSFIIRELTLHYNTmmgnlrskivnptgri
....|||||||| .|. |||||||... . |||||||.| . ||..|||..|.| || .||||..|.. . ..||...|. ..
krkayIAtqgPlaetiedFWRmvweqnsstiVmltkleEkgkvkchkYWPekgtetygeltVtleeeeeladyeirtfklkkkk................
dpnkkeyyssAQSTLLITHYQFIDWLEYGPQPPINSLVKFNKIISNQTEHKKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMREQRMM
... .....|..| . | .||... . ... .|...|||||||| | ||||.|| ... .. . .| .|| .|. .|.|| .
..........ssesreVrqFhFtsWPdhgvpesatslLdlirkvralnepdagPivVhCSaGVGRTGtfividamlerikeektvDiyqyvkalrkqRna
MIQTLDQYMLVHEAVLEQALCGDTQIVACDLQNTISSLSSSD-NASVTGFEAQFNVLE-QVSVPPQDAVCDVARQHPRKNRYQEILPTDQWRVHLKS
|.|| .||. .|||.|| ||.|.. . .|..... |.. . . ..||.|. |. |. . ..... . . .|||...||.... || |.
mVqteeQYiFiheailealacgntevesenlkqhlqkLaeveedtemtgleleFqrLatakeieleefavatkpknkkknrfsnilalescrvvlsa
|
|||||||||
subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 250-521 | 1.3e-78 | 258.9 | In-house | 16-287 (287) | alignment | ||
Range on Protein: 250-521
Range on HMM: 16-287/287.0
NASVTGFEAQFNVLEQVSVPPQDAVCDVARQHPRKNRYQEILPTDQWRVHLKSESPDYINAVFIPSYKNDKGFIIAQSPLRETRRDFWKMIFDREITTIV
. . .||. || |||||. ... ..| | |||...||. |. || || | ||||||||| .||..| ||||.||. .| |.|||.| ||..|.||
akgnegfknqftvleqvtqredevthniasqnkdknRltqilvpdnyrvllkgehpdyinavfidgykekkafiiaesPmfntarnfWkliddrnvtaiv
MLSPIMEGEEEACAQYWPKEGTIEFGEFTISVREE-WGHQSFSRKLLLIRNNKNNMLRRLAHFQVDGWSNDDITSCNEgAIINTMNLVKTLQRKSPNSPI
||. .| .||.| ||||.| .. .||..|.. .| .. ||| ....||.. ... .|. | . .. . .|. .. |||. |..|
mlcqekendeevcyqyWpeeksvvlGeyniellneevnagyierklevknknkagdkqqvkqyqitnWdstgkvtepq.tillvieemyktqrkrgntsi
LMHCSNMIGRSAVFCAAMATVDQMKSSSVVDVFQTVKNMRVNLPGAVQNKGQYKMIHTLAAAYVNLFSTSANF
..|||. .||||.|||| |... | |.|||| .|..|. ||.|| |||.| . .|.. |.| ..|
vvhCsdtvGrsamfcaaattinkckteGviDvfqvlksqriqkpgsvqtveqykfindivleyldsfetysdf
|
|||||||||
subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 251-517 | 2.8e-73 | 241.3 | In-house | 17-288 (290) | alignment | ||
Range on Protein: 251-517
Range on HMM: 17-288/290.0
ASVTGFEAQFNVLEQvSVPPQDAVCDVARQHPRKNRYQEILPTDQWRVHLK--SESPD----YINAVFIPSYKNDKGFIIAQSPLRETRRDFWKMIFDRE
.||..||..|.. . .. . ... . ..||...|...|. |. |. |. .| ||||..| ||..| .|..|.|. .| .||||.| ...
kgnegfrnqfkmlds.gesehtvtvgltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgykekkqyiatqgpvsntlvdFWkliwqek
ITTIVMLSPIMEGEEEACAQYWPKEGTIEFGEFTISVREEWGHQS-FSRKLLLIRNNKNNMLRRLAHFQVDGWSNDDiTSCNEGAIINTMNLVKTLQRKS
.| |||| |.| ... | ||||...| ..|||.| . .| ... ||| . .|... . . ..|. | ... |. .|. ... . |||.
vtiivmltniieegkvkCqqYWpdsdtkaygefsikllneetlneyierklevknknsagakqsvtqyqitnwdstg.kvtnpqtillvieemyktqrkr
PNSPILMHCSNMIGRSAVFCAAMATVDQMKSSSVVDVFQTVKNMRVNLPGAVQNKGQYKMIHTLAAAYVNLFST
| .|..|||. .|||||||||. |....|. |.|||| .|..|. || || . ||..|... |.. |.|
gntsivvHCSdtvgrsavfcaaattinkcktegvidvfqvlksqRiqkpgsvqtvqqyqgifqivltyldsfet
|
|||||||||
subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 229-519 | 1.1e-72 | 239.8 | In-house | 1-297 (298) | alignment | ||
Range on Protein: 229-519
Range on HMM: 1-297/298.0
GDTQIVACDLQNTISSLSSSDN-ASVTGFEAQFNVLEQVSVPPQDAVCDVARQ--HPRKNRYQEILPTDQWRVHLKS----ESPDYINAVFIPSYKNDKG
|.|.| | ||..... |.. .. ..||....|. |..|| ... .|||. .||||..|.. |. || |.. | |||||.|. .||. .
gnteieaedlkaalqklaavkkkkkltgyalefqrlnsvsseieeeekevarkpenkkkNRyadiialdssRvvLekedadeesdYiNAsflhaykgrna
FIIAQSPLRETRRDFWKMIFDREITTIVMLSPIMEGEEEACAQYWPKEGTIEFGEFTISVREEWGHQSFSRKLLLIRNNKNNMLRRLAHFQVDGWSNDDI
||..| || || |||.|. ...|.||||| .. | .. . .|||.||. ..||.|.|.... . . . | . ..|.. |.. .... |.. ..
fiatqaPltetvedFWrmvteedigtiVmltnleeldktkyhkywPdegketygeitvsllskeefadlivrklkvskkkeekerevrqlhftsWpdkgv
TScNEGAIINTMNLVKTLQRKSPNSPILMHCSNMIGRSAVFCAAMATVDQMKSSSVVDVFQTVKNMRVNLPGAVQNKGQYKMIHTLAAAYVNLFSTSA
.. |. .... .. |.. |... |.|....||. .||| |.| . ....| ..||||||.|| .|.. ||||| . ||. |... ... |.. .
pe.natsvldllrkvrasqqqagnkpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavlealdsfndei
|
|||||||||
0051299 | (Phosphotyrosine protein) phosphatases II | 238-512 | 2.9e-68 | 225.8 | In-house | 10-286 (288) | alignment | ||
Range on Protein: 238-512
Range on HMM: 10-286/288.0
LQNTISSLSssdNASVTGFEAQFNVLEQVSVPpQDAVCDVARQHPRKNRYQEILPTDQWRVHLKS----ESPDYINAVFIPSYKNDKGFIIAQSPLRETR
| ... | ..||....|. | .. .. . . . .. ||||. ||| |..||.|.. |. ||||| .|. |.... ||..| || .|
llklvlkll...angltglleefeellsllpd.ltlsaallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyidgynlkrkfIatqgPlpntv
RDFWKMIFDREITTIVMLSPIMEGEEEACAQYWPKEGTIEFGEFTISVREEWGHQSFSRKLLLIRNN----KNNMLRRLAHFQVDGWSNDDITScNEGAI
|||.|... ....|||| ...| . | |||||| .|....|..|. ..| .... | ..|. ... |. ||.. .| .... . . ..
edFWrmvweqnvrvIvmltklvelgrekcaqYwplggsltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpd.spell
INTMNLVKTLQRkSPNSPILMHCSNMIGRSAVFCAAMATVDQMKSSSVVDVFQTVKNMRVNLPGAVQNKGQYKMIHTLAAAYV
.. ..||.. .. |...|.. |||. .||...|.|. ..|.. .|||...|| .| ||.||. ||.... ... |.
ldflrlvrkala.sgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyealleyl
|
|||||||||
0050432 | (Phosphotyrosine protein) phosphatases II | 239-518 | 3.2e-68 | 225.7 | In-house | 25-305 (308) | alignment | ||
Range on Protein: 239-518
Range on HMM: 25-305/308.0
QNTISSLSS--SDNASVTGFEAQFNVLEQVSVpPQDAVCDVARQHPRKNRYQEILPTDQWRVHLkSESPDYINAVFIPSY--KNDKGFIIAQSPLRETRR
. .. .| . . ...|..|. | .| . . . . .. |||| ||| |. ||.| .|. ||||| ... | |... ||..|.|| .|
klsvldllkllekaldlglleeefeellsvkp.lleysvallpenkdkNrykdilpydhsRVkl.degsdYInAsyvdgyssklprkfIatqgPlpntve
DFWKMIFDREITTIVMLSPIMEGEEEACAQYWPKE---GTIEFGEFTISVREEWGHQSFSRKLLLIRNNKNNMLRRLAHFQVDGWSNDDITsCNEGAIIN
|||.|... ....|||| ..| . | |||||| | |..|.| ||. ...| .... . | ..|.... |.. ||. .| .... . ....
dFwrmvweqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseevlddytvrtleltnlgdgesrtvthfhytnWpdhgvP.pspeilld
TMNLVKTLQrksPNSPILMHCSNMIGRSAVFCAAMATVDQMKSSSVVDVFQTVKNMRVNLPGAVQNKGQYKMIHTLAAAYVNLFSTS
..||.. . |..||. |||. .||...|.|. ..|.. ||||..|| .| ||.||.. ||. .. ... |..|. |
flelvrksl...pggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylflyralleylklkltk
|
|||||||||
subfamily_PTPRD_pd | Subfamily PTPRD | 283-519 | 1.1e-66 | 220.7 | In-house | 50-288 (564) | alignment | ||
Range on Protein: 283-519
Range on HMM: 50-288/564.0
RKNRYQEILPTDQWRVHLK----SESPDYINAVFIPSYKNDKGFIIAQSPLRETRRDFWKMIFDREITTIVMLSPIMEGEEEACAQYWPKEGTIEFGEFT
.||||..|.. |. || |. |. ||||| || .|...| .| .| || || .|||.|.......|||||. . | ... |..|||..|| ..||.|
aKNRyanivaYdhsRVvLskvegdegsDYINAsfidgyrkrkayIAtqgPlaetiedFWRmvweqnsstiVmltkleEkgkvkchkYWPekgtetygelt
ISVREEWGHQSFSRKLLLIRNNKNNMLRRLAHFQVDGWSNDDITSCNeGAIINTMNLVKTLQrKSPNSPILMHCSNMIGRSAVFCAAMATVDQMKSSSVV
... || . .. . . ....|.. | .|. | . .. .... .. |..|. .. . ||. |||. .||. .|.. | ....|.. .|
VtleeeeeladyeirtfklkkkkssesreVrqFhFtsWPdhgvpesa.tslLdlirkvraln.epdagPivVhCSaGVGRTGtfividamlerikeektv
DVFQTVKNMRVNLPGAVQNKGQYKMIHTLAAAYVNLFSTSA
|..|.||..| . . ||.. || ||. . ... ..|.
DiyqyvkalrkqRnamVqteeQYiFiheailealacgntev
|
|||||||||
0036941 | (Phosphotyrosine protein) phosphatases II | 253-515 | 2.4e-66 | 219.4 | In-house | 12-280 (297) | alignment | ||
Range on Protein: 253-515
Range on HMM: 12-280/297.0
VTGFEAQFNVLEQVSVpPQDAVCDVARQHPRKNRYQEILPTDQWRVHLKSESPDYINAVFIPSYKNDKGFIIAQSPLRETRRDFWKMIFDREITTIVMLS
.... .| | .. . . . . .. |||| ||| |. ||.|..|. ||||| ... |. .. ||..| || .| |||.|... .|.||||.
lalllkefeellplll.lgslsvallpenleknRykdilpydhtRVklddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqnvtvIvmlt
PIMEGEEEACAQYWPKE--GTIEFGEFTISVREEWG--HQSFSRKLLLIRNNKNNMLRRLAHFQVDGWSNDDITScNEGAIINTMNLVKTLQRKS-PNSP
. .| . | |||||| | .....|.||. .... .... . | . ...|. |.. ||.. || ... . . ... ..||.. .... ...|
elvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpe.spaslldfielvrkvlkllpsggp
ILMHCSNMIGRSAVFCAAMATVDQMK---SSSVVDVFQTVKNMRVNLPGAVQNKGQYKMIHTLAAAYVNLF
.| |||. .|||..|.|| ..|.. ||....|| .| |||||. .||. .. . . ... .
vlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallellkkk
|
|||||||||
0040438 | (Phosphotyrosine protein) phosphatases II | 250-515 | 3.2e-65 | 215.8 | In-house | 14-279 (317) | alignment | ||
Range on Protein: 250-515
Range on HMM: 14-279/317.0
NASVTGFEAQFNVLEQVSVPpqDAVCDVARQHPRKNRYQEILPTDQWRVHLKSES----PDYINAVFIPSYKNDKGFIIAQSPLRETRRDFWKMIFDREI
. ..|... .|. | ..... . . ... |||| ||| |. ||.|.... ||||| ... .. . ||..|.|| .| |||.|... .
ksdftalleefedllslkld..tysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPlpntvedFwrmvweqgv
TTIVMLSPIMEGEEEACAQYWPKEGTIEFGEFTISVREEWGHQSFSRKLLLIRNNKNNMLRRLAHFQVDGWSNDDITScNEGAIINTMNLVKTLQRkSPN
|.|||| . .| . | |||||| ..|...|.||. ...| .... | . ..... |.. ||. || ... . . ... ...|.. .. .|.
tvivmLteleelgrekcaqYwplgetltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvpp.spdllldfleavreale.dpg
SPILMHCSNMIGRSAVFCAAMATVDQMKSSSVVDVFQTVKNMRVNLPGAVQNKGQYKMIHTLAAAYVNLF
.|.| |||. .||...|.|| ..|.. |||...|| .| |||||. .||. ...... |.. .
gpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleylkrk
|
|||||||||
0046845 | (Phosphotyrosine protein) phosphatases II | 255-518 | 7.8e-65 | 214.4 | In-house | 1-280 (284) | alignment | ||
Range on Protein: 255-518
Range on HMM: 1-280/284.0
GFEAQFNVLEQVSVPPQ-DAVCDVARQHPRKNRYQEILPTDQWRVHLKS-----ESPDYINAVFIPSY-----KNDKGFIIAQSPLRETRRDFWKMIFDR
|.|..| | .. |.. . . .. .. ||||. ||| |..||.||| |. ||||| ... | .. | ||..| || .| |||.|...
gleeefeellsltvklllslsvallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweq
EITTIVMLSPIMEGEEEACAQYWPKEG-TIEFGEFTISVREEWGHQSFSRKLLLIRNNK-NNMLRRLAHFQVDGWSnDDITSCNEGAIINTMNLVKTLQR
....|||| ...| . | |||||| || ....|.||. ...|. .... . | ..|.. .. |.. ||.. .| |. . . ... ..||..|..
nvrvIVmltelvengrekcaqYwplegevltygdftvtllseevkddytvrtleltnlgytgesrtvthfhytswp.dhgvppspedlleflrlvrelle
K-SPNSPILMHCSNMIGRSAVFCAAMATVDQMKSSS---VVDVFQTVKNMRVNLPGAVQNKGQYKMIHTLAAAYVNLFSTS
. ....||. |||. .||...|.|.. .|.. . .|||...|| .| ||.||. ||.... ... |..|. |
nlpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleylklkltl
|
|||||||||
0047943 | (Phosphotyrosine protein) phosphatases II | 250-511 | 8.4e-65 | 214.3 | In-house | 8-271 (273) | alignment | ||
Range on Protein: 250-511
Range on HMM: 8-271/273.0
NASVTGFEAQFNVLEQVSVpPQDAVCDVARQHPRKNRYQEILPTDQWRVHLKSESPDYINAVFIPSYKNDKGFIIAQSPLRETRRDFWKMIFDREITTIV
..|.....|. | .. . . . . . .. ||||. ||| |. ||.|.... ||||| ... |. . ||..| || .| |||.|... ...||
llgltllleefelllslkp.lltysvallpenkdknrykdilpydhsrvklgdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvweqnvrviV
MLSPIMEGEEEACAQYWPKEG---TIEFGEFTISVREEWGHQSFSRKLLLIRNNKNNMLRRLAHFQVDGWSNDDITScNEGAIINTMNLVKTLQRKS-PN
|| ...| . | |||||| || ....|.||. ...| .... | ..|.... | ||.. || .... . . ... ..||.. .... |
mLtelvelgrekcaqYwpleggelsltygkftvtllseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvpp.slesllefielvrkalealpsn
SPILMHCSNMIGRSAVFCAAMATVDQMKSSSVVDVFQTVKNMRVNLPGAVQNKGQYKMIHTLAAAY
.|.. |||. .||...|.|. .||.. |||...|| .| ||.||. ||.... ... |
gpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyealley
|
|||||||||
0050432 | (Phosphotyrosine protein) phosphatases II | 7-229 | 1.7e-63 | 210.1 | In-house | 105-302 (308) | alignment | ||
Range on Protein: 7-229
Range on HMM: 105-302/308.0
EQSQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSR---GSEDYGPFTVTLQKETTSNSFIIRELTLHYNTmmgnlrskivnp
...|.|||||||. || |||||||... |||||||.|. |.|| ||||. ||. ||.||||| .|.. .....|.|.| ..
klprkfIatqgPlpntvedFwrmvweqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseevlddytvrtleltnlg............
tgridpnkkeyyssAQSTLLITHYQFIDWLEYGPQPPINSLVKFNKIISNQTehKKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMRE
. .. .||.....| ..| | ...|..| ... .. ..|||||||| | ||||.|| . . . .| .|.. .| .||
..............dgesrtvthfhytnWpdhgvPpspeilldflelvrksl..pggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklRe
QRMMMIQTLDQYMLVHEAVLEQALCG
||..|.||..||.....|.|| ...
qRpgmvqtpeqylflyralleylklk
|
|||||||||
0051299 | (Phosphotyrosine protein) phosphatases II | 8-225 | 1.4e-62 | 207.2 | In-house | 90-285 (288) | alignment | ||
Range on Protein: 8-225
Range on HMM: 90-285/288.0
QSQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSRGSEDYGPFTVTLQKETTSNSFIIRELTLHYNTMMGnlrskivnptgri
...|.|||||||. || |||||||... |||||||.|. |.|| ||||..||. ||..|||| .|.. .....|.|.. ......
lkrkfIatqgPlpntvedFWrmvweqnvrvIvmltklvelgrekcaqYwplggsltygditvtllseevlddytvrtlevtnldlld.............
dpnkkeyysSAQSTLLITHYQFIDWLEYGPQPPINSLVKFNKIISNQTEHKKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMREQRMM
. .. .||.....| ..| . ...|..| ... .. ....||.||||| | ||||.|| . . . ..| .|.. .| .||||..
.........gdgesrtvthfhytnwpdhgvpdspellldflrlvrkalasgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpg
MIQTLDQYMLVHEAVLEQ
|.||..||..|.||.||
mvqtpeqyrfvyealley
|
|||||||||
0043336 | (Phosphotyrosine protein) phosphatases II | 248-511 | 1.7e-62 | 206.8 | In-house | 14-276 (278) | alignment | ||
Range on Protein: 248-511
Range on HMM: 14-276/278.0
SDNASVTGFEAQFNVLEQVSVppQDAVCDVARQHPRKNRYQEILPTDQWRVHLKSES----PDYINAVFIPSYKNDKGFIIAQSPLRETRRDFWKMIFDR
.. |.....| | .. . . . .. |||| ||| |. ||.|.... ||||| ... |. ..||..| || || |||.|...
lllnlktllllefeellsfkl..dtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpetvedFwrmvwel
EITTIVMLSPIMEGEEEACAQYWPkEGTIEFGEFTISVREEWGHQSFSRKLLLIRNNKNNMLRRLAHFQVDGWSNDDITScNEGAIINTMNLVKTLQRkS
.|||||| . .| . . |||||| .|....|.||. ...| .. . . | . |.... | |.. || ... . . ... .. |.. .. .
gvttivmLtelvelgrvkcaqYwp.ggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpe.slsllldflkavreale.d
PNSPILMHCSNMIGRSAVFCAAMATVDQMKSSSVVDVFQTVKNMRVNLPGAVQNKGQYKMIHTLAAAY
.|.|.| |||. .||...|.|. ..|... ||....|| .| |||||. ||.... ... |
sngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyealley
|
|||||||||
subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 243-518 | 1.3e-61 | 203.4 | In-house | 11-289 (305) | alignment | ||
Range on Protein: 243-518
Range on HMM: 11-289/305.0
SSLSSSDNASVTGFEAQFNVLEQVsVPPQDAVCDVARQHPRKNRYQEILPTDQWRVHLKSESP--DYINAVFIPSYKNDKGFIIAQSPLRETRRDFWKMI
. . .. | .|.|||.. | . . | .. |... ... . .|..|. .. |.. . ||||| .. .||. | .|.||.||..| .|||..|
ayikearvysdkgleaqykslyee.eesidvgkkeankaknrlkeitlldddriiltekeslddsdyinasyvdgykrkkkyivaqgPlkntvadfWrli
FDREITTIVMLSPIMEGEEEACAQYWPKEGTI--EFGEFTISVREEWGHQSF-SRKLLLIRNNKNNMLRRLAHFQVDGWSNDDITScNEGAIINTMNLVK
.. ..|||||. ..||... | ||||.. | |||||.. ...| . . ||| . ..... | . ..|. | .. . ..... .. |.
veekvstivmltklveggkdkCrqYWpesktekkefgefsvelksektasdyieRklkisiededkesrtvlqyqltdWPdhGvpq.fatsllslikrvq
TLQRKSPNSPILMHCSNMIGRSAVFCAAMATVDQMKSSSVVDVFQTVKNMRVNLPGAVQNKGQYKMIHTLAAAYVNLFSTS
|.|. . |.| |||. .||. ||.| ....| |||||. .|..| . ...||.. || .| . ... . ||
kdqkkdkgvpllVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkmvqtldqYvflhdaldelitcgdts
|
|||||||||
subfamily_PTPRK_pd | Subfamily PTPRK | 7-247 | 1.7e-61 | 202.8 | In-house | 83-298 (314) | alignment | ||
Range on Protein: 7-247
Range on HMM: 83-298/314.0
EQSQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSRGSEdYGPFTVTLQKETTSNSFIIRELTLHYntmmgnlrskivnptgr
......|.|||||. || ||||.|..|....|||||.|.| |.||..||| .. ||.. |.| . .. . ...| ....
krpaafivtqgPlqetvkdfWrlvydencasivmltelvevgrvkClkyWPedtev.ygdikvelvetellaelvvrifrvek.................
idpnkkeYYSSAQSTLLITHYQFIDWLEYGPQPPINSLVKFNKIISNQTEHKKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMREQRM
. . . .. ..||. | ... ..|.|. . . ...|...|.||||||.|.||||.|| .. . . .|...|. .| .|....
.......largqeeirevrqfqflgWpdhdvPvsatgllklvrrvkksqeeeaGrivvhCsaGaGrtGtfiaidivldmieregvvdvfnavktlrsrkv
MMIQTLDQYMLVHEAVLEQALCGDTQIVACDLQNTISSLSS
|..| .||.......|| .|||.| | ....... . .
nmveteeqykfiydvileaclcgetaipvsefkalylesir
|
|||||||||
DSPc_SM00195 | 256-512 | 2.1e-61 | 202.9 | In-house | 2-262 (263) | alignment | |||
Range on Protein: 256-512
Range on HMM: 2-262/263.0
FEAQFNVLEQVSVPPqdAVCDVAR-QHPRKNRYQEILPTDQWRVHLKSES----PDYINAVFIPSYKNDKGFIIAQSPLRETRRDFWKMIFDREITTIVM
....|. ||. | . .... . .||||..||| |. ||.||.| ||||| .| ....| .|..| || .| .|||.|........|||
lkeefekleestspk..etteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivm
LSPIMEGEEEACAQYWPKE--GTIEFGEFTISVREEWGHQ-SFSRKLLLIRNNKNNMLRRLAHFQVDGWSNDDITsCNEGAIINTMNLVKTLQRKSpNSP
|. .| ..| |..|||.| |. .||.... ..|. .. .. .. | ....... |.. ..|. .| . .. .. ... .. ||. ...| ..|
lteeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvp.dstksvlellravkksksts.sgp
ILMHCSNMIGRSAVFCAAMATVDQMKSSSVVDVFQTVKNMRVNLPGAVQNKGQYKMIHTLAAAYV
|. |||. .||...|... ...... . ||.|..||..| . ||.||.. ||..|.. ...|.
ivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi
|
|||||||||
PTPc_SM00194 | 256-512 | 2.1e-61 | 202.9 | In-house | 2-262 (263) | alignment | |||
Range on Protein: 256-512
Range on HMM: 2-262/263.0
FEAQFNVLEQVSVPPqdAVCDVAR-QHPRKNRYQEILPTDQWRVHLKSES----PDYINAVFIPSYKNDKGFIIAQSPLRETRRDFWKMIFDREITTIVM
....|. ||. | . .... . .||||..||| |. ||.||.| ||||| .| ....| .|..| || .| .|||.|........|||
lkeefekleestspk..etteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivm
LSPIMEGEEEACAQYWPKE--GTIEFGEFTISVREEWGHQ-SFSRKLLLIRNNKNNMLRRLAHFQVDGWSNDDITsCNEGAIINTMNLVKTLQRKSpNSP
|. .| ..| |..|||.| |. .||.... ..|. .. .. .. | ....... |.. ..|. .| . .. .. ... .. ||. ...| ..|
lteeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvp.dstksvlellravkksksts.sgp
ILMHCSNMIGRSAVFCAAMATVDQMKSSSVVDVFQTVKNMRVNLPGAVQNKGQYKMIHTLAAAYV
|. |||. .||...|... ...... . ||.|..||..| . ||.||.. ||..|.. ...|.
ivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 282-508 | 3.9e-61 | 201.8 | Pfam-A | 2-233 (235) | alignment | ||
Range on Protein: 282-508
Range on HMM: 2-233/235.0
PRKNRYQEILPTDQWRVHL-KSES-PDYINAVFIPSYKNDKGFIIAQSPLRETRRDFWKMIFDREITTIVMLSPIMEGEEEACAQYWP--KEGTIEFGEF
.||||..||| |. ||.| .||. ||||| .. .||..| ||..| || .| |||.|........|||| .| ..|.|||||| .|.. ..|..
kkknRykdilpydktrvklkgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesltygdi
TISVR--EEWGHQSFSRKLLLIRNNKNN-MLRRLAHFQVDGWSNDDITSCNEGAIiNTMNLVKTLQrKSPNSPILMHCSNMIGRSAVFCAAMATVDQMKS
.. .. |. .... . | ....|.. |.. .... .| . .. ..... . .... |.. . .. ..|.. |||. .||...|.|... ..|...
kvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespksll.dlirkveksk.eaksgpvvVhCsaGvgRtgtfvaldilleqlea
SSVVDVFQTVKNMRVNLPGAVQNKGQYKMIHTLA
. |||.|.||..| . ||.||. ||.... .
eeevdvlqivkelRkqRpgmvqsleqYiflykai
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 282-508 | 3.9e-61 | 201.8 | In-house | 2-233 (235) | alignment | ||
Range on Protein: 282-508
Range on HMM: 2-233/235.0
PRKNRYQEILPTDQWRVHL-KSES-PDYINAVFIPSYKNDKGFIIAQSPLRETRRDFWKMIFDREITTIVMLSPIMEGEEEACAQYWP--KEGTIEFGEF
.||||..||| |. ||.| .||. ||||| .. .||..| ||..| || .| |||.|........|||| .| ..|.|||||| .|.. ..|..
kkknRykdilpydktrvklkgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesltygdi
TISVR--EEWGHQSFSRKLLLIRNNKNN-MLRRLAHFQVDGWSNDDITSCNEGAIiNTMNLVKTLQrKSPNSPILMHCSNMIGRSAVFCAAMATVDQMKS
.. .. |. .... . | ....|.. |.. .... .| . .. ..... . .... |.. . .. ..|.. |||. .||...|.|... ..|...
kvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespksll.dlirkveksk.eaksgpvvVhCsaGvgRtgtfvaldilleqlea
SSVVDVFQTVKNMRVNLPGAVQNKGQYKMIHTLA
. |||.|.||..| . ||.||. ||.... .
eeevdvlqivkelRkqRpgmvqsleqYiflykai
|
|||||||||
0039614 | (Phosphotyrosine protein) phosphatases II | 252-515 | 4.3e-61 | 202.3 | In-house | 30-292 (297) | alignment | ||
Range on Protein: 252-515
Range on HMM: 30-292/297.0
SVTGFEAQFNVLEQVSVPpqdAVCDVARQHPRKNRYQEILPTDQWRVHLKSES-----PDYINAVFIPSYKN-DKGFIIAQSPLRETRRDFWKMIFDREI
| |.....| | .. .. .. .. ||||..||| |. ||.||.| ||||| ... |. .. ||..| || || |||.|... .
sktllllefeellslkpd...ysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIatqgPlpetvedFwrmvweqgv
TTIVMLSPIMEGEEeACAQYWPKEGTiEFGEFTISVREEWGHQSFSRKLLLIRNnkNNMLRRLAHFQVDGWSnDDITSCNEGAIINTMNLVKTLQRKS-P
|.|||| . .| . |||||| ||. ..|.||. .... .. . . | ..| |. | . |||. || |. . . ... ..||.. .... .
tvivmLtklvelgr.kcaqywpeegg.tygdftvtllkvehldgytvrtlevtn..ngesrtvthfqytgwp.dhgvppslellleflelvrealaelpk
NSPILMHCSNMIGRSAVFCAAMATVDQMKSSSVVDVFQTVKNMRVNLPGAVQNKGQYKMIHTLAAAYVNLF
. |.| |||. .||...|.|| ..|... |||...|| .| |||||. .||. .. ... ... .
ggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydallellkrk
|
|||||||||
0045450 | (Phosphotyrosine protein) phosphatases II | 251-511 | 4.4e-61 | 202.6 | In-house | 24-303 (307) | alignment | ||
Range on Protein: 251-511
Range on HMM: 24-303/307.0
ASVTGFEAQFNVLEQVSVP-PQDAVCDVARQHPRKNRYQEILPTDQWRVHLKS-----ESPDYINAVFI--------PSYKNDKGFIIAQSPLRETRRDF
..||....|. | .| |. . . . .. ||||..||| |. ||.|.| |. ||||| .. ..|.... ||..|.|| || ||
dfltgllkefekllsvtvfllgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydlkrkfIatqgPlpetvedF
WKMIFDREITTIVMLSPIMEGEEEACAQYWPKEGTI-EFGEFTISVREEWGHQSFSRKLLLIRNN-KNNMLRRLAHFQVDGWSNDDITScNEGAIINTMN
|.|... .|.||||.. .| . | |||||| ||. ..|.||. ...| .... . | . .. .... |.. ||. || .... . . ... ..
wrmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpdhgvpp.sfeelldfie
LVKTLQRKS-PNSPILMHCSNMIGRSAVFCAAMATVDQMKSSSV---VDVFQTVKNMRVNLPGAVQNKGQYKMIHTLAAAY
.|.. .... ...|.| ||| .||...|.|| .|... . ||....|| .| |||||| .||. .. ... .
evrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeallel
|
|||||||||
subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 243-507 | 5.5e-61 | 201.1 | In-house | 10-274 (288) | alignment | ||
Range on Protein: 243-507
Range on HMM: 10-274/288.0
SSLSSSDNASVTGFEAQFNVLEQVSVPPQDAVCDVARQHpRKNRYQEILPTDQWRVHLKS----ESPDYINAVFIPSYKNDKGFIIAQSPLRETRRDFWK
. . . |||. ..|.| .. .. . |. . .||||..||| |. ||.|| .. ||||| .| ..|..| .| .|.|| .| |||.
akvakksarnrtgfseeynsLaalektksvtagrlavna.kknRyrnilpyDekrvklkkleeeagaDYinasyidgekkkkkyiatqgPladtvndfWe
MIFDREITTIVMLSPIMEGEEEACAQYWPKEGT-IEFGEFTISVREEWGHQSFSRKLLLIRnnKNNMLRRLAHFQVDGWSNDDITScNEGAIINTMNLVK
........|||||. ..||... | .|||.... ..|..|. ..|. ..| . ||. |.. ... ..| .|..... .. ... .. ||
lvyenktstivmltelveggktkCeeYWPdadkpknyGsvtvtlveskeledfvlrkllle..kkkteleitqyqylaWpdhgvPe.skapllellrqvk
TLQRKSpNSPILMHCSNMIGRSAVFCAAMATVDQMKSSSVVDVFQTVKNMRVNLPGAVQNKGQYKMIHTL
. . . ||..|||. .||. .| |. | .|..... ..||. ||...| . . ||.. || |.
vanqad.tgpiivhCsaGvGrtgtFialdalidaveeedyiDvagtvaklRkqRallvqtlkqYefiyev
|
|||||||||
0046845 | (Phosphotyrosine protein) phosphatases II | 7-230 | 5.9e-61 | 201.7 | In-house | 74-278 (284) | alignment | ||
Range on Protein: 7-230
Range on HMM: 74-278/284.0
EQSQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSRG-SEDYGPFTVTLQKETTSNSFIIRELTLhyntmmgnlrskivnptg
...|.|||||||. || |||||||.... |||||.| |. |.||.||||. | . ||.||||| .|.. .....|.|.|
yikkkfIatqgPlpntvedFwrmvweqnvrvIVmltelvengrekcaqYwplegevltygdftvtllseevkddytvrtlel..................
ridpnkkEYYSSAQSTLLITHYQFIDWLEYGPQPPINSLVKFNKIISNQTE--HKKGPIVVHCSTGGGRTGAFIGMSCSIKDALTES---IIDIPAVVTI
.... . .. .||.....| ..| | ...|..| ... .. | ...|||||||| | ||||.|| . . .. .|. .|.. .|
.......tnlgytgesrtvthfhytswpdhgvppspedlleflrlvrellenlpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkr
MREQRMMMIQTLDQYMLVHEAVLEQALCGD
.||||..|.|||.||..|.||.|| ....
lreqRpgmvqtleqyrfvyealleylklkl
|
|||||||||
0040438 | (Phosphotyrosine protein) phosphatases II | 8-241 | 7.6e-61 | 201.5 | In-house | 84-291 (317) | alignment | ||
Range on Protein: 8-241
Range on HMM: 84-291/317.0
QSQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSRGSEDYGPFTVTLQKETTSNSFIIRELTLHYN-Tmmgnlrskivnptgr
...|.|||||||. || |||||||... . |||||.| |. |.|| ||||.... ||.|||||..|.. .....|.|.. .. .
lkrkfIatqgPlpntvedFwrmvweqgvtvivmLteleelgrekcaqYwplgetltygdftvtllseeelagitlrtlevedlgd...............
idpnkkeyyssaQSTLLITHYQFIDWLEYGPQPPINSLVKFNKIISNQTEHKKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMREQRM
. .. .||.....| ..|. | ...|..| ... .. |...||..|||| | ||||.||.. . . .| .|.. .| .||||.
............sesrtvthfhytgWpdhgvppspdllldfleavrealedpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRp
MMIQTLDQYMLVHEAVLEQALCGDTQIVACDLQNT
...||..||. ...|.|| ....| . |..| .
gavqtpeqyrflydalleylkrkltlepaselklk
|
|||||||||
0036941 | (Phosphotyrosine protein) phosphatases II | 8-238 | 1.7e-60 | 200.2 | In-house | 76-289 (297) | alignment | ||
Range on Protein: 8-238
Range on HMM: 76-289/297.0
QSQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSR--GSEDYGPFTVTLQKETT--SNSFIIRELTLHYNTMmgnlrskivnp
...|.|||||||. || |||||||... |||||.| |. |.|| ||||. .| ||.|||||..... ......|.|.. ..
lkrkfIatqgPlpntvedFWrmvweqnvtvIvmltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgn...........
tgridpnkkeyyssaQSTLLITHYQFIDWLEYGPQPPINSLVKFNKIISNQTEH--KKGPIVVHCSTGGGRTGAFIGMSCSIKDAL---TESIIDIPAVV
. .. .||.....| ..|. . ..||..| . . .. .. ..||..|||| | ||.|.||.. . . .| .||. .|
...............gesrtvthfhytgwpdhgvpespaslldfielvrkvlkllpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileav
TIMREQRMMMIQTLDQYMLVHEAVLEQALCGDTQIVACDL
.||||....|||.||. ..||.|| ....| . ...|
kklReqRpgavqtleqyrflyeallellkkkltkepllkl
|
|||||||||
subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 253-518 | 5.3e-60 | 198.1 | In-house | 22-289 (319) | alignment | ||
Range on Protein: 253-518
Range on HMM: 22-289/319.0
VTGFEAQFNVLEQVSVPpQDAVCDvARQHPRKNRYQEILPTDQWRVHLK----SESPDYINAVFIPSYKNDKGFIIAQSPLRETRRDFWKMIFDREITTI
|..| .|. |.. . . .. . .|||||.||. |. || |. .|. ||||| || .|.. . || .|.|| .| |||.|....|. ..
etllekefkllkeavnd.tfdsas.keenkkknryqnilaydrtrvvlseldgvegsdyinasfidgyqerekfiatqaPlentiedfWrmvWeeessiv
VMLSPIMEGEEEACAQYWPKEGTIEFGEFTISVREEWGHQSFSRKLLLIRNNKNNM-LRRLAHFQVDGWSNDDITSCNEgAIINTMNLVKTLQRKSPNSP
|||. . | . . .|||.| |.|.... . || . . . | ........ |.. ||| |...|. .... .. .. ..|. . |
vmltklveklkvklkkywpeenfeeyGrlivtleeeeeledyiirklklnkkssevetRevkhfqyteWpdhdvPekat.slldllkrirksrektqsgP
ILMHCSNMIGRSAVFCAAMATVDQMKSSSVVDVFQTVKNMRVNLPGAVQNKGQYKMIHTLAAAYVNLFSTS
| .|||. .|| |.. |.....| .|.|||.||...|. . ||.. |||.|. ..|. ..|
ivvhCsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyealleaveagdte
|
|||||||||
0047943 | (Phosphotyrosine protein) phosphatases II | 8-224 | 1.2e-59 | 197.3 | In-house | 75-270 (273) | alignment | ||
Range on Protein: 8-224
Range on HMM: 75-270/273.0
QSQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSRG---SEDYGPFTVTLQKETTSNSFIIRELTLHYNTmmgnlrskivnpt
...|.|||||||. || |||||||.... |||||.|.|. |.|| ||||. | |. ||.||||| .|.| .....|.|.| ..
lkrkfiatqgPlpntvedfwrmvweqnvrviVmLtelvelgrekcaqYwpleggelsltygkftvtllseetkddytvrtleltnlg.............
gridpnkkeyyssAQSTLLITHYQFIDWLEYGPQPPINSLVKFNKIISNQTEH--KKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMR
. .. .||... .| ..| | ..||..| ... .. |. ..||.||||| | ||||.|| . . . .| .|.. .| .|
.............tgesrtvthfhytgwpdhgvppslesllefielvrkalealpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllr
EQRMMMIQTLDQYMLVHEAVLE
.||..|.||..||....||.||
sqRpgmvqtpeqyrflyealle
|
|||||||||
subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 256-519 | 1.3e-58 | 193.5 | In-house | 22-287 (318) | alignment | ||
Range on Protein: 256-519
Range on HMM: 22-287/318.0
FEAQFNVLEQVSVPPQDAVCdVARQHPRKNRYQEILPTDQWRVHLKS----ESPDYINAVFIPSYKNDKGFIIAQSPLRETRRDFWKMIFDREITTIVML
...... |.... . . .||||. ||. |. ||.|. |. ||||| .|. |...| .| ||.|| || .|||.|..... ..||||
lseeyerlsrseetvtslks.lepvnkaknryanilaydhtrvkLqmlegeegsDyinanyidGyrrkkayiaaqaPlpetieDfWrmvWeqnsavivml
SPIMEGEEEACAQYWPKEGTIEFGEFTISVREEWGHQSFSRKLLLIRNNKNNMLRRLAHFQVDGWSNDDITScNEGAIINTMNLVKTLQRKSPNSPILMH
. ..| . ...|||..|....|. .. ..|| ... . . ....... | ... |.. .. . . . ... . |.. |.|| ..||..|
tqeeergkakvhryWPskgsrsygklvvelkeevelsdyvlrefkvtrteeeesrqvrqyhytsWpdegvpe.sgaslldlvrqvskaqqksgagpivvh
CSNMIGRSAVFCAAMATVDQMKSSSVVDVFQTVKNMRVNLPGAVQNKGQYKMIHTLAAAYVNLFSTSA
|| .|| ||.| . ....| ..||||||||..| . . || . ||..|.. ... . | .
CsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqtedqyefiydvllealasgdtev
|
|||||||||
subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 280-516 | 3.5e-58 | 191.8 | In-house | 8-246 (250) | alignment | ||
Range on Protein: 280-516
Range on HMM: 8-246/250.0
QHPRKNRYQEILPTDQWRVHLKSES----PDYINAVFIPSYKNDKGFIIAQSPLRETRRDFWKMIFDREITTIVMLSPIMEGEEEaCAQYWPKEGTIEFG
| |||| .|.. |. || |..|. |||||.|. .|.. | ||..|.|| .| |||.|.......|||||. . | |.. . |||| |.. ..|
qnkeknryadiialdssrvvLekekgdkesdyinasflhgyderkafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqywPvekaekyG
EFTISVREEWGHQSFSRKLLLIRNNKNNMLRRLAHFQVDGWSNDDITScNEGAIINTMNLVKTLQRKSPNSPILMHCSNMIGRSAVFCAAMATVDQMKSS
. |.|. .. . . . | . ..|.. | . ... | . . . |... .. |.. |... |.|....||. .||| |.| | ....| .
dvtvsllskeefadytkrklklskakkaderivrqlhfvvWPdkgvPe.vatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidavlerlkke
SVVDVFQTVKNMRVNLPGAVQNKGQYKMIHTLAAAYVNLFS
|||||. .| .| . |.||. . || ...... ... ..
kvvdvfkvikvlrkdrphavesleqyvfvyeiilkaldsve
|
|||||||||
DSPc_SM00195 | 7-224 | 6.2e-58 | 191.5 | In-house | 66-260 (263) | alignment | |||
Range on Protein: 7-224
Range on HMM: 66-260/263.0
EQSQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSR--GSEDYGPFTVTLQKETTSN-SFIIRELTLHYNTMmgnlrskivnp
....|||||||||. || |||||||.|| |||||. .|. ..||..|||. |.|..| ..|.|..... . ..|.|.|.| ...
nkkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegk...........
tgridpnkkeyyssaQSTLLITHYQFIDWLEYGPQPPINSLVKFNKIISNQTEHKKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMRE
. | .|.||. .| . | . .|.... . . .......||||||||.| ||||.|. ... .. .|. .|| ..|. .|.
...............eetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRk
QRMMMIQTLDQYMLVHEAVLE
||..|.|||.||. ..||.||
qRpgmvqtleqYlfiyeaile
|
|||||||||
PTPc_SM00194 | 7-224 | 6.2e-58 | 191.5 | In-house | 66-260 (263) | alignment | |||
Range on Protein: 7-224
Range on HMM: 66-260/263.0
EQSQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSR--GSEDYGPFTVTLQKETTSN-SFIIRELTLHYNTMmgnlrskivnp
....|||||||||. || |||||||.|| |||||. .|. ..||..|||. |.|..| ..|.|..... . ..|.|.|.| ...
nkkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegk...........
tgridpnkkeyyssaQSTLLITHYQFIDWLEYGPQPPINSLVKFNKIISNQTEHKKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMRE
. | .|.||. .| . | . .|.... . . .......||||||||.| ||||.|. ... .. .|. .|| ..|. .|.
...............eetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRk
QRMMMIQTLDQYMLVHEAVLE
||..|.|||.||. ..||.||
qRpgmvqtleqYlfiyeaile
|
|||||||||
0040439 | (Phosphotyrosine protein) phosphatases II | 275-511 | 1.6e-57 | 190.3 | In-house | 5-245 (249) | alignment | ||
Range on Protein: 275-511
Range on HMM: 5-245/249.0
CDVARQHPRKNRYQEILPTDQWRVHLKS----ESPDYINAVFIPSYKNDKGFIIAQSPLRETRRDFWKMIFDREITTIVMLSPIMEGEEEACAQYWPKEG
. .. ||||. ||| |. ||.|.. . ||||| .|. |. . ||..| || || |||.|... ||.||||.. .| . | |||||| .|
vallpenkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywplgg
TIEFGEFTISVREEWGHQSFSRKLLLIRNNKNNMLRRLAHFQVDGWSnDDITSCNEGAIINTMNLVKTLQRKS-PNSPILMHCSNMIGRSAVFCAAMATV
..|.|.||. .... .... . | . |.... |. |.|. .| |. .. . ... ...|.. ... ...|.| |||. .||...|.|| .
sleygdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwp.dhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylml
DQMKSSSVVDVFQTVKNMRVNLPGAVQNKGQYKMIHTLAAAY
.|.. ||....|| .| |||||| .||. .. ... .
eqlekelgvdleeavkllrsqRpgavqnpeqyrflyeallel
|
|||||||||
subfamily_Ptp69D_pd | Subfamily Ptp69D | 248-512 | 2e-57 | 189.7 | In-house | 16-286 (307) | alignment | ||
Range on Protein: 248-512
Range on HMM: 16-286/307.0
SDNASVTGFEAQFNVLEQVsVPPQDAVCDVARQHPRKNRYQEILPTDQWRVHLK----SESPDYINAVFIPSYKNDKGFIIAQSPLRETRRDFWKMIFDR
... . |.. .. ||. ..... ||||..| . |. || || .|. ||||| || .||. | ||.|| |. .| |||.|| .
rkrdtdfglakeyekLear.eidkstkvsekkenalknRyedikafDktRvkLkkingkedsdYinasfikgykekkkfiaaqdPveatigDfWRmiaeq
EITTIVMLSPIMEGEEEACAQYWPKEGTIEFGEFTISVREEWGHQSFSRKLLLIRNNKNNM-----LRRLAHFQVDGWSnDDITSCNEGAIINTMNLVKT
|.|.||||| . | ... ||.|||.| ....|. . . .| |. . .. | . ..|.. |.. .. || | . .... .. |.
evtlivmlsnlteknrkkcakYWpiedevqygdilvklvseekhsdyiiReldvskkkeesgevedsrkvvqyhytgWk.DskvPevargllklieqvre
LQRKSpNSPILMHCSNMIGRSAVFCAAMATVDQMKSSSVVDVFQTVKNMRVNLPGAVQNKGQYKMIHTLAAAYV
|.... .|||..|||. |||..| | ..|.| ||.|.|||..| . . ||. ||. .. . |
lykln.rsPivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnllvqsleqYvflyralldys
|
|||||||||
subfamily_PTPRA_pd | Subfamily PTPRA | 255-511 | 2.2e-57 | 189.4 | In-house | 33-294 (330) | alignment | ||
Range on Protein: 255-511
Range on HMM: 33-294/330.0
GFEAQFNVLEQVSVppqDAVCDVARQ--HPRKNRYQEILPTDQWRVHLKS----ESPDYINAVFIPSYKNDKGFIIAQSPLRETRRDFWKMIFDREITTI
| .|| | .. .|....| . .|||. .||| | ||.| |. ||||| || ||. . || || |..|| |||.||.... .||
lfreefnalPagpi...qatlelaskeenkeknrvvnilPydfsrvilsvkeGveesdyinasfidGykekdkfiaaqGPkeetvedfwrmiweqksati
VMLSPIMEGEEEACAQYWPKEGTIEFGEFTISVREEWGHQSFSRKLLLIR----NNKNNMLRRLAHFQVDGWSNDDITSCNEGaIINTMNLVKTLQRKSP
|||. . | .|| ||||||.||.. .|. ...|..| .... . .|.. . ... | .. | .| . . . | ... .. ||.|...|
vmltelkerkeekcaqywPdeGlvtyGnirvevedetvlvdytvrkflvqqlpdatrekksrlvrqfhftswPdvGvPfepiG.mlkllkkvkklnqqsa
NsPILMHCSNMIGRSAVFCAAMATVDQMKSSSVVDVFQTVKNMRVNLPGAVQNKGQYKMIHTLAAAY
. || .||| .||. |.. | ....|. .||||..||..| . | || . ||..|. |
g.pivvhcsaGvGrtGtfivldavlervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvlley
|
|||||||||
0043336 | (Phosphotyrosine protein) phosphatases II | 8-224 | 2.4e-57 | 189.8 | In-house | 86-275 (278) | alignment | ||
Range on Protein: 8-224
Range on HMM: 86-275/278.0
QSQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPsRGSEDYGPFTVTLQKETTSNSFIIRELTLHYN--Tmmgnlrskivnptg
...|.|||||||. || |||||||... |||||.| |. |.|| |||| .||. ||.|||||.||.. . ...| |.....
vprkfiatqgPlpetvedFwrmvwelgvttivmLtelvelgrvkcaqYwp.ggsltygdftvtllkeehlddytvrtlevtnlgdg..............
ridpnkkeyyssaqSTLLITHYQFIDWLEYGPQPPINSLVKFNKIISNQTEHKKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMREQR
.. .|||....| ..| .....|..| |.. .. |...||..|||| | ||||.||.. . . .| .|.. .| .||||
..............esrtvthyhylgwpdhgvpeslsllldflkavrealedsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqR
MMMIQTLDQYMLVHEAVLE
....||..||. ..||.||
pgavqtpsqyrflyealle
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 8-224 | 4.9e-57 | 188.4 | Pfam-A | 40-235 (235) | alignment | ||
Range on Protein: 8-224
Range on HMM: 40-235/235.0
QSQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWP--SRGSEDYGPFTVTLQ-KET-TSNSFIIRELTLHYNTMMGnlrskivnp
...|.|||||||. |. |||||||||| .|||||.|.| | ||.|||| ...|. || ..|.|. ||. ......|.|.|. ..
ekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesltygdikvelkekekedekeytlrklelkkkkees.........
tgridpnkkeyyssaqSTLLITHYQFIDWLEYGPQPPINSLVKFNKIISNQTEHKKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMRE
. ...... .| ..| . .||... . . ...|.|.||.|||||.| |||| |. ... .. . .|. .|. .| .|.
................ekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRk
QRMMMIQTLDQYMLVHEAVLE
||..|.|.|.||. ...|.||
qRpgmvqsleqYiflykaile
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 8-224 | 4.9e-57 | 188.4 | In-house | 40-235 (235) | alignment | ||
Range on Protein: 8-224
Range on HMM: 40-235/235.0
QSQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWP--SRGSEDYGPFTVTLQ-KET-TSNSFIIRELTLHYNTMMGnlrskivnp
...|.|||||||. |. |||||||||| .|||||.|.| | ||.|||| ...|. || ..|.|. ||. ......|.|.|. ..
ekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesltygdikvelkekekedekeytlrklelkkkkees.........
tgridpnkkeyyssaqSTLLITHYQFIDWLEYGPQPPINSLVKFNKIISNQTEHKKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMRE
. ...... .| ..| . .||... . . ...|.|.||.|||||.| |||| |. ... .. . .|. .|. .| .|.
................ekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRk
QRMMMIQTLDQYMLVHEAVLE
||..|.|.|.||. ...|.||
qRpgmvqsleqYiflykaile
|
|||||||||
0039614 | (Phosphotyrosine protein) phosphatases II | 9-229 | 1.8e-56 | 187.2 | In-house | 100-292 (297) | alignment | ||
Range on Protein: 9-229
Range on HMM: 100-292/297.0
SQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRiKCSQYWPSRGSeDYGPFTVTLQKETTSNSFIIRELTLhyntmmgnlrskivnptgrid
..|.|||||||. || |||||||... .||||||| |. | || ||||..|. ||.||||| |... . ...|.|..
trkfIatqgPlpetvedFwrmvweqgvtvivmLtklvelgr.kcaqywpeegg.tygdftvtllkvehldgytvrtlev.....................
pnkkeyySSAQSTLLITHYQFIDWLEYGPQPPINSLVKFNKIISNQTEH--KKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMREQRM
. . .. .||.|...| ..|. | ...| .| ... .. .. |.||..|||| | ||||.||.. . .| .|.. .| .||||.
.......tnngesrtvthfqytgwpdhgvppslellleflelvrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRp
MMIQTLDQYMLVHEAVLEQALCG
...||..||. ...|.|| ...
gavqtpsqyrflydallellkrk
|
|||||||||
0042113 | (Phosphotyrosine protein) phosphatases II | 280-512 | 2e-56 | 186.5 | In-house | 8-243 (245) | alignment | ||
Range on Protein: 280-512
Range on HMM: 8-243/245.0
QHPRKNRYQEILPTDQWRVHLKSES----PDYINAVFIPSYKNDKGFIIAQSPLRETRRDFWKMIFDREITTIVMLSPIMEGEEEACAQYWPKEGTIEFG
.. |||| .||| |. ||.|.... ||||| ... |. ..||..| ||.|| |||.|... |||||||.. .| . . |||||| ......|
enkdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywplgesltyg
EFTISVREEWGHQSFSRKLLLIRNNKNNMLRRLAHFQVDGWSnDDITSCNEGAIINTMNLVKTLQRKSPNSPILMHCSNMIGRSAVFCAAMATVDQMKSS
.||. ...| .... . | . |.... | |.. .| |. . . ... ...|.. .....| |.| ||| .||...|.|| ..|...
dftvtllseehlddytvrtlevtnlgddesrevihyhylpwp.dhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleqleke
SVVDVFQTVKNMRVNLPGAVQNKGQYKMIHTLAAAYV
|.....|| .| |||||. .||. .. ... ..
lgvsleeavkelrsqRpgavqtpsqyrflyeallell
|
|||||||||
subfamily_PTPRB_pd | Subfamily PTPRB | 247-507 | 5.6e-56 | 184.7 | In-house | 18-280 (293) | alignment | ||
Range on Protein: 247-507
Range on HMM: 18-280/293.0
SSDNASVTGFEAQFNVLEQVSVPpQDAVCDVARQHPRKNRYQEILPTDQWRVHL----KSESPDYINAVFIPSYKNDKGFIIAQSPLRETRRDFWKMIFD
. . | ..| ... |..| | ... . . ||||..||| |. ||.| .... ||||| .|| |. . || .| || ||. |||.|...
kmkadsdlrfseeyeelkavgkd.qavkaaelavnraknrytnilpydhsrvkLaalkdesgsDYinanyipgynsprefiatqGPlpetvddfWrmvwe
REITTIVMLSPIMEGEEEACAQYWPKE-GTIEFGEFTISVREEWGHQSFSRKLLLIRNnkNNMLRRLAHFQVDGWSNDDITSCNEgAIINTMNLVKT-LQ
.. ..|||| ..|. . | .|||.. .. .|. .... .| . . . |.|.. ... |.. ... |.. .. . . .... .. |.. ..
kkssiivmltqlvekgkvkCeeYWPadeepvlyGdikvtlvaeeeledwvirelkiek..ekeerkvrqyhftsWpdhgvPektk.tlldfvrtvreaie
RKSPNSPILMHCSNMIGRSAVFCAAMATVDQMKSSSVVDVFQTVKNMRVNLPGAVQNKGQYKMIHTL
... ..||..||| .||. .| | ....... .||.| .| ..| . ||.. || .||.
ktaskrPivvhCsaGvGRtGtfialdrllqaieeedyvdifgivaelReeRnllvqtekqYifihqc
|
|||||||||
0045098 | (Phosphotyrosine protein) phosphatases II | 269-513 | 1.5e-55 | 183.9 | In-house | 21-273 (278) | alignment | ||
Range on Protein: 269-513
Range on HMM: 21-273/278.0
PPQDAVCDVARQHPRKNRYQEILPTDQWRVHlksespDYINAVFIPSYknDKGFIIAQSPLRETRRDFWKMIFDREITTIVMLSPIMEGEEEACAQYWPK
.|.. . . . . |||| .||| |. ||. ||||| .|..| .| ||..| || .| |||.|... ||.|||| . .|.. | ||||||
ipseitpalylgnldknRykdilpydhsrVk......dYINAsyidgy..pkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaqywpe
EGTIEFGEFTISVREEWGHQSFSRKLLLIRNN----KNNMLRRLAHFQVDGWSNDDITSCN-EGAIINTMNLVKTLQR------------KSPNSPILMH
.|....|.||. . .| .. . ||..| .... | . |.. .| .. | . ... .. .. .. ... |.| |
ggsltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvlVH
CSNMIGRSAVFCAAMATVDQMksSSVVDVFQTVKNMRVNLPG-AVQNKGQYKMIHTLAAAYVN
|| .||.....||. ... ..||....|| .| || ||||..||. .. ... ...
CsaGvgRtGtlvaaylmlell..eggvdlleavkelrsqRpglavqnleqyrflyefllelll
|
|||||||||
0045450 | (Phosphotyrosine protein) phosphatases II | 8-224 | 2.1e-55 | 184.0 | In-house | 105-302 (307) | alignment | ||
Range on Protein: 8-224
Range on HMM: 105-302/307.0
QSQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSRGSE-DYGPFTVTLQKETTSNSFIIRELTLHYNTMMGnlrskivnptgr
...|.|||||||. || |||||.|... .|||||.| |. |.|| ||||. |.| ||.||||| .|.. .....| |..... |
lkrkfIatqgPlpetvedFwrmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgtg............
idpnkkeyyssaqSTLLITHYQFIDWLEYGPQPPINSLVKFNKIISNQTEH--KKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESI---IDIPAVVTIM
.. .||.....| ..| | ...|..| ... . |. |.||..|||| | ||||.||.. .. .| . .|.. .| .
.............esrtvthfhytgwpdhgvppsfeelldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkll
REQRMMMIQTLDQYMLVHEAVLE
||||. ..|...||. ..||.||
reqRpgavqnpeqyrflyealle
|
|||||||||
0045098 | (Phosphotyrosine protein) phosphatases II | 9-230 | 1.3e-54 | 180.8 | In-house | 63-276 (278) | alignment | ||
Range on Protein: 9-230
Range on HMM: 63-276/278.0
SQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSRGSEDYGPFTVTLQKETTSNSFIIRELTLHYNTMMGNLrskivnptgrid
..|.|||||||. || |||||.|... .|||||.|.|. |.|| ||||..||. ||.|||||..|.. . ...| |.... |.. .
pkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaqywpeggsltygdftvtllseevlddytlrtllvtnltvered............
pnkkeyyssaQSTLLITHYQFIDWLEYGPQPPI--NSLVKFNKIISNQTEH-------------KKGPIVVHCSTGGGRTGAFIGMSCSIKDAltESIID
.. .||.... | ..|. . .|. .. . | . .. ..||..|||| | ||||..... . .. |. .|
..........lesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvlVHCsaGvgRtGtlvaaylmlell..eggvd
IPAVVTIMREQRMM-MIQTLDQYMLVHEAVLEQALCGD
.. .|. .|.||.. ..|.|.||. ..|..|| |.|.
lleavkelrsqRpglavqnleqyrflyefllelllrgk
|
|||||||||
0040439 | (Phosphotyrosine protein) phosphatases II | 8-224 | 2.7e-53 | 176.5 | In-house | 52-244 (249) | alignment | ||
Range on Protein: 8-224
Range on HMM: 52-244/249.0
QSQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSRGSEDYGPFTVTLQKETTSNSFIIRELTLHYNTmmgnlrskivnptgri
.....|||||||. || |||||.|... .|||||.|.| |.|| ||||..|| || ||||| ..........|.|.|...
ikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywplggsleygdftvtllsvevkddytvrtleltnly................
dpnkkeyyssAQSTLLITHYQFIDWLEYGPQPPINSLVKFNKIISNQTEH--KKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMREQR
.... ..|.|..|| ..| | ...|..| ... . |. |.||..|||| | ||||.||.. . .| .|.. .| .|.||
..........dgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdleeavkllrsqR
MMMIQTLDQYMLVHEAVLE
....|...||. ..||.||
pgavqnpeqyrflyealle
|
|||||||||
subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 278-508 | 4.1e-53 | 175.2 | In-house | 39-273 (315) | alignment | ||
Range on Protein: 278-508
Range on HMM: 39-273/315.0
AR--QHPRKNRYQEILPTDQWRVHL----KSESPDYINAVFIPSYKNDKGFIIAQSPLRETRRDFWKMIFDREITTIVMLSPIMEGEEEACAQYWPK--E
|| . .||||..||| |. || | .| ||||| .|.|...|| .| .| ||. . |||.|... ..|||||.. ||. |.||||.
aretinfkknryknilPldsarvkleviddsPdsdyinasyiksvdddkayiasqgPlkasvddfwrmvlqekvttivmvtkkqegdkikcrqywPdrka
GTIEFGEFTISVRE-EWGHQSFSRKLlLIRNNKNnmLRRLAHFQVDGWSNDDITScNEGAIINTMNLVKTLqRKSPNSPILMHCSNMIGRSAVFCAAMAT
..|||.. ... . | . ||| .|. .. |... || .| . . . ..... . ||. ... . ..|.||| .||. |.....
dsvefGsikvellsleadtdgvarkl.vtrksee..srtvtqfqftewPdkGvdk.qtssllklikevkad.ngkkefsllvhcsaGvGrtGvvisidev
VDQMKSSSVVDVFQTVKNMRVNLPGAVQNKGQYKMIHTLA
|.|.| ...||||..|||.| . | || . .| .|.
vaqikrtrsvdvfnfvknlrakrpylvqteeeyafiydav
|
|||||||||
subfamily_PTPRG_pd | Subfamily PTPRG | 250-506 | 3.7e-52 | 172.3 | In-house | 15-281 (563) | alignment | ||
Range on Protein: 250-506
Range on HMM: 15-281/563.0
NASVTGFEAQFNVLEQVSV-PPQDAVCDVARQHPRKNRYQEILPTDQWRVHLKSESP-----DYINAVFIPSYKNDKGFIIAQSPLRETRRDFWKMIFDR
. .||...|. |.. .. || ... ||||| .|.. |. ||.|.. . ||||| .| |. | ||..| ||..| |||.||...
adgdigfseefealqsetiskdldaehsqkpenkrKnRylnivaydrsRvklsplpgkkkklDYinAnyidGyqkskafiatqgplkdtfddFWrmiWeq
EITTIVMLSPIMEGEEEACAQYWPKEGTIEFGEFTISVREEWGHQSFSRKLLLIRN-----NKN-NMLRRLAHFQVDGWSNDDITSCNegaiINTMNLVK
. ..|||.. . | . . | .||||......|.... || . . . . | |.| .|. . .. ... | . . . . . .. ||
nvaiivmitnlvergrrkcdvYWPkdesetygalqvtlieeevlalytvrtlviknlklkkkkqcdteklvrqyhytkWPdhgvPehs....lpvLifvk
TLQRKSP--NSPILMHCSNMIGRSAVFCAAMATVDQMKSSSVVDVFQTVKNMRVNLPGAVQNKGQYKMIHT
.. . ||..|||. .||. .... . . |... ..|.||...| .| . . ||.. || .|
kssaankaeaGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvqteEqYiflhd
|
|||||||||
subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 254-511 | 6.4e-52 | 171.5 | In-house | 26-283 (297) | alignment | ||
Range on Protein: 254-511
Range on HMM: 26-283/297.0
TGFEAQFNVLEQVSVPPQDAVcdVARQHPRKNRYQEILPTDQWRVHLKSES----PDYINAVFIPSYKNdkGFIIAQSPLRETRRDFWKMIFDREITTIV
. |. .|. | . . || . |.||. |||.|. ||.|.. ||.|| |....|. .| | | ..| |||.|..| ...|||
dvfseeflclpeaniqpqtva..ekkvnfeksRYkniLPydssRvkLaivnddpdsDyvnasfvkgnkh..rlittqmPmkatvadfWamvldeqvstiv
MLSPIMEGEEeACAQYWPKEGTIEFGEFTISVREEWGHQSFSRKLLLIRNNKNNMLRRLAHFQVDGWSNDDITS-CNEGAIINTMNLVKTLQRKSPNSPI
||. |... ||.||...|. .||. .. . . |... | ....|. . | . .| | .... . .... .. |. . ..|.
mlnddnerdk.kcaryWsdkgvttfGdvsvvllsvsereGfikrelevtkgkakarrvvkqyqfveWPdkaverkdsassllklisevrkdfsqnaegPl
LMHCSNMIGRSAVFCAAMATVDQMKSSSVVDVFQTVKNMRVNLPGAVQNKGQYKMIHTLAAAY
|.||.. .|| .|... | ..| ||.|..|| .| . | || | |||... . .
lvhclaGvGrtgvlltidsvvaeakrekevdifglvkklrqerpylvqtkeqykfvyvavlea
|
|||||||||
0042113 | (Phosphotyrosine protein) phosphatases II | 8-224 | 9.8e-52 | 171.1 | In-house | 50-241 (245) | alignment | ||
Range on Protein: 8-224
Range on HMM: 50-241/245.0
QSQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSRGSEDYGPFTVTLQKETTSNSFIIRELTLHYN-Tmmgnlrskivnptgr
...|.|||||||. || |||||.|... .|||||.. |. |.|| ||||...| || ||||| .|.. .....|.|..... .
itpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywplgesltygdftvtllseehlddytvrtlevtnlgd...............
idpnkkeyyssaQSTLLITHYQFIDWLEYGPQPPINSLVKFNKIISNQTE-HKKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMREQR
.. ..||....| ..|. . ...|..| ... .. . ...||..|||| | ||||.||.. . . .| .... .| .|.||
............desrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleqlekelgvsleeavkelrsqR
MMMIQTLDQYMLVHEAVLE
....||..||. ..||.||
pgavqtpsqyrflyealle
|
|||||||||
subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 4-224 | 1.6e-51 | 170.1 | In-house | 84-277 (288) | alignment | ||
Range on Protein: 4-224
Range on HMM: 84-277/288.0
KDDEQSQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSRGS-EDYGPFTVTLQKETTSNSFIIRELTLHyntmmgnlrskivn
.......||||||||| || |||..|...|. |||||.| |. . || .|||. . . || .||||... . ..|. |.| |.
dgekkkkkyiatqgPladtvndfWelvyenktstivmltelveggktkCeeYWPdadkpknyGsvtvtlveskeledfvlrkllle..............
ptgridpnkkeyysSAQSTLLITHYQFIDWLEYGPQPPINSLVKFNKIISNQTEHKKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMR
.. | ||.||. | . | . |... ... .. . . |||.|||| | |||| || . . |. .| ||. ..|. .|
..............kkkteleitqyqylaWpdhgvPeskapllellrqvkvanqadtgpiivhCsaGvGrtgtFialdalidaveeedyiDvagtvaklR
EQRMMMIQTLDQYMLVHEAVLE
.||....||| ||. ..|..|.
kqRallvqtlkqYefiyevlls
|
|||||||||
subfamily_Ptp69D_pd | Subfamily Ptp69D | 8-245 | 2e-51 | 169.9 | In-house | 89-305 (307) | alignment | ||
Range on Protein: 8-245
Range on HMM: 89-305/307.0
QSQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSRGSEDYGPFTVTLQKETTSNSFIIRELTLHYNTM-MGNLrskivnptgr
...|.|| |.|.. |. |||||... . ||||..|.| | ||..||| || |.| .| . . .||||| . . |..
ekkkfiaaqdPveatigDfWRmiaeqevtlivmlsnlteknrkkcakYWpiedevqygdilvklvseekhsdyiiReldvskkkeesgev..........
idpnkkeyyssaQSTLLITHYQFIDWLEYGPQPPINSLVKFNKIISNQTEHKKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMREQRM
. . .. |.. | .. ..|.|. . . . .....|||||||.| ||.| |. .. .. .| .|| ..| .|.||
............edsrkvvqyhytgWkDskvPevargllklieqvrelyklnrsPivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRn
MMIQTLDQYMLVHEAVLEQALCGDTQIVACDLQNTISSL
...| |.||. .. |.|. |||.. ||...| .|
llvqsleqYvflyralldyssygdtdedvddledaierl
|
|||||||||
subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 256-507 | 2.7e-51 | 169.2 | In-house | 20-271 (515) | alignment | ||
Range on Protein: 256-507
Range on HMM: 20-271/515.0
FEAQFNVLEQVSVPPQDaVCDVARQHpRKNRYQEILPTDQWRVHL----KSESPDYINAVFIPSYKNDKGFIIAQSPLRETRRDFWKMIFDREITTIVML
| .|. | . || |.. . .||||..||| |. || | . ||.|| .|||..||| .| .| |.. . |||..... ..|||.|.
fseefhdlpgpniypqt.vaqeeinf.kknryknilPydsvrvklevindnPhsdyfnasyipsfdndkayiasqgPnkasvddfWrlvlqenvttiamv
SPIMEGEEEACAQYWPK--EGTIEFGEFTIS-VREEWGHQSFSRKLLLIRNNKnnmLRRLAHFQVDGWSNDDITSCnEGAIINTMNLVKTLQRKSPnSPI
. ||. |..|||. ...||.. .. | | . ||| ...... | .. |. .| . . ... . ||. . . |.
tklkegdkikcgkyWPdkpgdsvkfGsikvelvsleactggikrkltvlkgdd...srtvtqfhfteWPdkGvpkh.tssllklikevkadhgqyt.hpl
LMHCSNMIGRSAVFCAAMATVDQMKSSSVVDVFQTVKNMRVNLPGAVQNKGQYKMIHTL
..||| .|| |..... | ..| . .||||..|.|.| . | || . || .|.
iihcsaGvGrtGvvisidsvvahakttrmvdvfnfvtnirqkrpylvqtqeqyafiyga
|
|||||||||
subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 7-233 | 5e-51 | 168.7 | In-house | 96-297 (298) | alignment | ||
Range on Protein: 7-233
Range on HMM: 96-297/298.0
EQSQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSRGSEDYGPFTVtlqkettsnsfiireltlhyNTMMGNLRSKIVNPTGR
.... .||||.|| .||.||||||..|.. .|||||.|.| ..|...|||..|.| || .|| . . . ..... .
kgrnafiatqaPltetvedFWrmvteedigtiVmltnleeldktkyhkywPdegketygeitv....................sllskeefadlivrklk
IDPNKKEyyssaqSTLLITHYQFIDWLEYGPQPPINSLVKFNKIIS-NQTEHKKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMREQR
. .|.| .. . . .|. | . | .|.... . . .|.. .. |..|.|| | ||.|.|| .. . . .|. .|. || ..|..|
vskkkee......kerevrqlhftsWpdkgvpenatsvldllrkvrasqqqagnkpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkr
MMMIQTLDQYMLVHEAVLEQALCGDTQI
. ..|| .||. ..||||| .....|
pgavqteeqYvfiyeavlealdsfndei
|
|||||||||
subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 5-224 | 6.3e-51 | 168.1 | In-house | 68-266 (274) | alignment | ||
Range on Protein: 5-224
Range on HMM: 68-266/274.0
DDEQSQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSRG----SEDYGPFTVTLQKETTSNSFIIRELTLHYNTMMGNlrski
||.|. |.|||||| || |||||..||.. |||||||.| . ||..|.| . || || . .. .| .. | . .|.|.|.| . .
ydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneqkCavyfPdaedyeiserygdveikvekiverndysvrklvlkylerers.....
vnptgridpnkkeyyssaqstllITHYQFIDWLEYGPQPPINSLVKFNKIISN---QTEHKKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAV
..|| . || . .|.|... . ... ....| .|.||||| | ||||.||..| .... |...|. .
.......................vkhywytdWPdhksPddantlldlvleveesreeenaklapvvvhCsaGiGrtGcfiaisiavrqlreeivvdvlki
VTIMREQRMMMIQTLDQYMLVHEAVLE
|. .| .| |.|| .|| |.|.|. .
vcnlrldrGGmvqtseqyelihralcl
|
|||||||||
subfamily_PTPRG_pd | Subfamily PTPRG | 8-240 | 7e-51 | 168.1 | In-house | 89-301 (563) | alignment | ||
Range on Protein: 8-240
Range on HMM: 89-301/563.0
QSQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSRGSEDYGPFTVTLQKETTSNSFIIReltlhyntmmgnlrskivnpTGRI
.|...||||||| |. |||||.|.... |||.|.|.|. | || .|||. .||.|| ..|||..| . . .| | |
kskafiatqgplkdtfddFWrmiWeqnvaiivmitnlvergrrkcdvYWPkdesetygalqvtlieeevlalytvr....................tlvi
DPNKKEYYSSAQSTLLITHYQFIDWLEYGpqPPINSLVKFNKIISNQT--EHKKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMREQR
|.. ..... .|...|.. .| . | | || . . .. ... ... ||||||||.|.|||| .| .. .|. .|..... .. .| ||
knlklkkkkqcdteklvrqyhytkWPdhg..vPehslpvLifvkkssaankaeaGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqR
MMMIQTLDQYMLVHEAVLEQALCGDTQIVACDLQN
...|| .||. .|.|.|| . ..|...| ....
nflvqteEqYiflhdalleaiasketellaeqvee
|
|||||||||
0037934 | (Phosphotyrosine protein) phosphatases II | 11-224 | 2.5e-50 | 166.6 | In-house | 45-240 (243) | alignment | ||
Range on Protein: 11-224
Range on HMM: 45-240/243.0
KYIATQGPLDRTVVD----FWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPsrGSEDYGPFTVTLQKETTSNSFIIRELTLHyntmmgnlrskivnptgr
..|||||||. || | ||||.|... .|||||.|.| |.|| |||| |.. ||.||||| .|.. .....|.|.|
rliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywp..gevtygdftvtllseehlddytvrtllle..................
idpnkkeYYSSAQSTLLITHYQFIDWLEYGPQPPINSLVKFNKIISNQ--------TEHKKGPIVVHCSTGGGRTGAFIGMSCSIKDAlteSiIDIPAVV
... . |.|..||... | ..|. . ...|..| ... . .....||..|||| | ||||..| . .. . .|. .|
.......nldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtliaaylmllll...g.vdleeav
TIMREQRMM-MIQTLDQYMLVHEAVLE
.||||.. ..||..||. ..||.||
kllreqRpgkavqtpsqyrflyealle
|
|||||||||
subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 246-507 | 3.3e-50 | 165.8 | In-house | 16-274 (315) | alignment | ||
Range on Protein: 246-507
Range on HMM: 16-274/315.0
SSSDNASVTGFEAQFNVLEQVSVPPQDAVCDVARQhpRKNRYQEILPTDQWRVHL----KSESPDYINAVFIPSYKNDKGFIIAQSPLRETRRDFWKMIF
. .. ||. ... . . | | .. . .|||| .|...|. ||.| . . ||.|| ||. |. . .| ||.|. .. .|||...|
aqkkastkngfkqdyesipggqlhpldvakkienk..qknryiniiaydksrvqlpllendphsdyvnanfidGynkkrryiaaqgpnvasvkdfwrlvf
DREITTIVMLSPIMEGEEEACAQYWPKEgTIEFGEFTISVREEWGHQSFSRKLLliRNNKNNMLRRLAHFQVDGWSNDDITSCnegaIINTMNLVKTLQR
. .|..||||. ..|||.. . .||| . . .|..|.. ..| .. .. . | .. .| . ... | . ... |. |||..| ..
eedigkivmltnlvegekrkaekywpdk.kviyGkitvtrkseevnteytvrtl..svvfgdnirevvqlhytswpdmgvpky....tiplmnlirtvkq
KSPN--SPILMHCSNMIGRSAVFCAAMATVDQMKSSSVVDVFQTVKNMRVNLPGAVQNKGQYKMIHTL
| ..|..|||. .||. |.. | .||.. ..||.. ....| | ..|| ||..|.
hhtnsvgaivvhcsaGvGrtGtfitldavldqaeaenaidvynfitgvrqnrikmvqvaeqyqfiyda
|
|||||||||
subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 8-224 | 6.5e-50 | 164.5 | In-house | 83-291 (301) | alignment | ||
Range on Protein: 8-224
Range on HMM: 83-291/301.0
QSQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPS--RGSEDYGPFTVTLQKETTSNSFIIRELTLHYNTMMGnlrskivnpTG
...|.||.|||...|.|||||..|||| .|||.|.|.|. . || ||||. ||..|||||||..|.. .|.||.|... . . |
ekkkfiaaqgpmkktlvdfWrliwqekpvsivmvtnlkegtkskceqywpnseaeseefgpftvtlvneqvyPdfvirqlnvkiqdgsn.........ng
RIDPN------KkeyyssaqSTLLITHYQFIDWLEYGP-QPPINSLVKFNKIISNQTEHKKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVV
.| . | |. .. .| .|| . | . | | ...| | .||.||||| . .|.| .. .| .. . | ..|. |.
yierkfkvksdk........sswdvlqlqvtdWpqdGvvreprtvLqviddvihrqqkigggpvvVHCSdtVsrsGvYcsvsiglEQckaegVVdvfqvt
TIMREQRMMMIQTLDQYMLVHEAVLE
.| ... ...||.||. ..... .
kavrrskpgaVtTLeqytsiydvidm
|
|||||||||
subfamily_PTPN23_pd | Subfamily PTPN23 | 247-506 | 8.8e-50 | 164.1 | In-house | 8-274 (288) | alignment | ||
Range on Protein: 247-506
Range on HMM: 8-274/288.0
SSDNASVTGFEAQFNVLEQVS-VPPQDAVCDVARQHPRKNRYQEILPTDQWRVHLKSESPDYINAVFIPSYKND-KGFIIAQSPLRETRRDFWKMIFDRE
. .|.....|. ||| .. . .|. .. |||...||| |. ||.|... ||||| |. . ||..|.||..| |||.|....
rkmldgktaldkkfkeleqkqdkearkrsiaiaklyseknrsrdilPyDhnRvklrgskDDYinAsfvkdlspgcPdfiatqaPlqstlnDFWlmvyeqk
ITTIVMLSPIMEGEEEACAQYWPKE--GTIEFGEFTISVREEWGHQSFSRKLLLIRNNKNNMLRRLAHFQVDGWSNDDITSCNEgAIINTMNLVKT---L
.|||| | ... ...|||.. | .||......... . .... | .. .... . . | |. |.. . . | ... .. |..
ssviVmllskeelgkpkvdrYwPedkgetvkfgdlsvtlksvretethvervlkletldadavksvshlqltsWpelGvPasPe.tllqfldevesayea
QRKSPNSPILMHCSNMIGRSAVFCAAMATVDQMKS-SSVVDVFQTVKNMRVNLPGAVQNKGQYKMIHT
... . |...||| .||. ||. .| | ... ..|. | |. .| . ||.| |.|.
vqrksktPlvvhCsaGvgRtgvfalvyaavrelekgnglldiiqvvsrlreqRrfmvqekeqlkfsye
|
|||||||||
subfamily_PTPRK_pd | Subfamily PTPRK | 279-507 | 1e-49 | 164.1 | In-house | 41-272 (314) | alignment | ||
Range on Protein: 279-507
Range on HMM: 41-272/314.0
RQHPRKNRYQEILPTDQWRVHLKSE----SPDYINAVFIPSYKNDKGFIIAQSPLRETRRDFWKMIFDREITTIVMLSPIMEGEEEACAQYWPKEGTIeF
.. .|||...||. |. || |.. | ||||| .| |||. . ||..| ||.|| .|||....| . ..||||. ..| | .|||..... .
denreknrsgdilaydrsrvflitidgdpssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasivmltelvevgrvkClkyWPedtev.y
GEFTISVRE-EWGHQSFSRKLLLIR-NNKNNMLRRLAHFQVDGWSNDDITsCNEGAIINTMNLVKTLQRKsPNSPILMHCSNMIGRSAVFCAAMATVDQM
|.. . . | | . .| . . . . . . | . .|| ||.. |. ... .... . ||. | . . .|..|||. ||. .|.| .| .
gdikvelvetellaelvvrifrveklargqeeirevrqfqflgWpdhdvP.vsatgllklvrrvkksqee.eaGrivvhCsaGaGrtGtfiaidivldmi
KSSSVVDVFQTVKNMRVNLPGAVQNKGQYKMIHTL
. .|||||..||..| . . |. . |||.|.
eregvvdvfnavktlrsrkvnmveteeqykfiydv
|
|||||||||
0037934 | (Phosphotyrosine protein) phosphatases II | 280-510 | 1.1e-49 | 164.5 | In-house | 9-240 (243) | alignment | ||
Range on Protein: 280-510
Range on HMM: 9-240/243.0
QHPRKNRYQEILPTDQWRVHLksESPDYINAVFIPSYKNdkgFIIAQSPLRETRRD----FWKMIFDREITTIVMLSPIMEGEEEACAQYWPkeGTIEFG
.. ||||. ||| |. ||.| |. ||||| .|. ... .|. | || || | ||.|... ||.|||| . .| . | |||||| |....|
enlsknrysdilpydhsrvkl..egsdyinanliyvtpr...liatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywp..gevtyg
EFTISVREEWGHQSFSRKLLLIRNNK-NNMLRRLAHFQVDGWSndDITSCN-EGAIINTMNLVKTLQRK-------SPNSPILMHCSNMIGRSAVFCAAM
.||. . .| .... ||..| . .. | |.. .| | . . ... .. |.. ... ....|.| ||| .||.....||
dftvtllseehlddytvrtlllenldlddltrlvihyhylpwp..dhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtliaay
ATVDQMkssSvVDVFQTVKNMRVNLPG-AVQNKGQYKMIHTLAAA
... . ||....|| .| || |||. .||. .. ...
lmllll...g.vdleeavkllreqRpgkavqtpsqyrflyealle
|
|||||||||
subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 280-513 | 2.3e-49 | 162.9 | In-house | 27-269 (274) | alignment | ||
Range on Protein: 280-513
Range on HMM: 27-269/274.0
QHPRKNRYQEILPTDQWRVHLKSES-----PDYINAVFIPSYKN-DKGFIIAQSPLRETRRDFWKMIFDREITTIVMLSPIMEGEEEACAQYWPKEGTI-
. .||||..||| .. || |.||| .|||| .| |.. .| .. .| || .| |||.||. .|.. |||| . | .|. ||.|.|.. .
gsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneqkCavyfPdaedye
---EFGEFTISVREEWGHQSFSRKLLLIRNNKNnmLRRLAHFQVDGWSnDDITSCNEGAIINTMNLVKTLQRK--SPNSPILMHCSNMIGRSAVFCAAMA
..|.. | |.. .. .| . |.... .. |.. |. | | . . ....... |.. ... . .|...||| ||| .| |.
iserygdveikvekiverndysvrklvlkyler..ersvkhywytdWP.dhksPddantlldlvleveesreeenaklapvvvhCsaGiGrtGcfiaisi
TVDQMKSSSVVDVFQTVKNMRVNLPGAVQNKGQYKMIHTLAAAYVN
.| |.. ..||||...| |.|.. | ||.. ||..|| . |..
avrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralclylk
|
|||||||||
subfamily_PTPN12_pd | Subfamily PTPN12 | 273-512 | 4e-49 | 162.0 | In-house | 32-277 (290) | alignment | ||
Range on Protein: 273-512
Range on HMM: 32-277/290.0
AVCDVARQHPRKNRYQEILPTDQWRVHLKSE----SPDYINAVFIPSYKNDKGFIIAQSPLRETRRDFWKMIFDREITTIVMLSPIMEGEEEACAQYWPK
. . . .. .||||..||| |. ||.|. . ||||| || .... .| ||.|| .| |||.||.. ... .||. ..| . |..|||.
teagekeenvkknrykDilPydksrvelskieeeegsdYinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCerYWpe
E--GTIEFGEFTISVRE-EWGHQSFSRKLLLIRNNknNMLRRLAHFQVDGWSNDDITSCnEGAIINTMNLVKTLQRkSPNSPILMHCSNMIGRSAVFCAA
| ..|||||.... | .. .. | . | .... . |.. |. | . .. | . ... ..||..||. | ..|...||| .|| . .|
egeeelefgefevtleeekavdddflirtLkveaq..kesrkvyqfhYtaWPDhgvPss.aksllelielvrelqe.sedaPlvvhCsaGvGrtGtiiai
MATVDQMKSSSV---VDVFQTVKNMRVNLPGAVQNKGQYKMIHTLAAAYV
. ...|. . .|||. | ..| . . .|| | ||.... | .|
dyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelv
|
|||||||||
subfamily_PTPN9_pd | Subfamily PTPN9 | 273-507 | 5.4e-49 | 161.8 | In-house | 34-285 (297) | alignment | ||
Range on Protein: 273-507
Range on HMM: 34-285/297.0
AVCDVARQHPRKNRYQEILPTDQWRVHLKS----ESPDYINAVFIPSYKNDKGFIIAQSPLRETRRDFWKMIFDREITTIVMLSPIMEGEEEACAQYWP-
. . | .||||...| |. ||.|.. | ||||| |. ||. |.|| .| ||..| .|||.|....|. .||| ..| |.||||
flasklranleknrytdvlcydetrvvlakvdedeasdyinanfvdGykqkkafiatqGplkktvsdfWrmvWeqevlvivmttrvvergrlkcgqyWpl
-KEGTIEFGEFTISVREEWGHQSFSRKLLLIRNNKNNMLRRLAHFQVDGWSNDDITSCNeGAIINTMNLVKTLQR------------KSPNSPILMHCSN
.| ..|||....|. | .. . . | |.| |.. |.. |||. .| . . | .... .. |. | . . ||..|||
eeessaefgdlsvsnveveeeedykvrvleiknvkteesrkvthfqflsWPdyGvPssa.aslldvlekvrekqalavkelgdewkghpsgPPivvhcsa
MIGRSAVFCAAMATVDQMKSSSVVDVFQTVKNMRVNLPGAVQNKGQYKMIHTL
|||. |.. ....... ..|||..||| .| ..| ||.. .
GiGrtGtfitldiclsrleevgtvdvvetvkllrtqrafsiqtpeqyefcyla
|
|||||||||
subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 248-506 | 4.8e-48 | 159.1 | In-house | 28-285 (319) | alignment | ||
Range on Protein: 248-506
Range on HMM: 28-285/319.0
SDNASVTGFEAQFNVLEQVSVPPQDAVCDVARQHPRKNRYQEILPTDQWRVHLKS----ESPDYINAVFIPSYKNDKGFIIAQSPLRETRRDFWKMIFDR
. .| .|..|. . ...|. | | |||. .||. |. .| |. | ||||| |. |.. . .| || || .| |||.||..
dfdddltklevefrracklgvnladqtfanldqnkdknriinilafdknvvklerliGeefsdyinasfvtGyqrkdkyiaaqGPldntladfWrmiwey
EITTIVMLSpimegeEEACAQYWPKEGTIEFGEFTISVREEWGHQSFS-RKLLLIRNNKNNMLRRLAHFQVDGWSNDDITSCNeGAIINTMNLVKTLQRK
...|||.|. .. |.||||... |. ..| ..| . . |.. | .. |.. |.. | || . .. .. |. |..|
ncstivllt......kdkcsqywplkivikeerfkvkvdsveetaeyvvrdielsedgkekdirkitqfhflGwpdvGvpdyp.sdlmrlvkkvrhltsk
-SPNSPILMHCSNMIGRSAVFCAAMATVDQMKSSSVVDVFQTVKNMRVNLPGAVQNKGQYKMIHT
. .|..||| .||. |. . . .|.|| . |||...|...| . . ||. |||.|..
enhranivvhcsaGvGrtGvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiys
|
|||||||||
subfamily_CG7180_pd | Subfamily CG7180 | 271-512 | 3.9e-47 | 155.3 | In-house | 32-290 (296) | alignment | ||
Range on Protein: 271-512
Range on HMM: 32-290/296.0
QDAVCDVARQHPRKNRYQEILPTDQWRVHLKS----ESPDYINAVFIPSYKNDKGFIIAQSPLRETRRDFWKMIFDREITTIVMLSPIMEGEEeACAQYW
| ... . |||. ...| |. || |.. |. ||||||.. |. .| .|. . | .|| .||....|.|| ..|.|. .. .. . .||
gdCagglrkenreknrdvkvvPyDynRvvLekldGeeksdYinavyvdsflkkkeyivteapkketvdefWrlvydeeisavvvLtktfdfak.mypsyw
PKEGTIEFGEFTISVREEWGHQSFSRKLL-LIRN---------NKNNMLRRLAHFQVDGWSNDDITSCNEGAIINTMNLVKTLQRKS----PNSPILMHC
|... ..||. . . || . . . | .. . . | . .||. | .| |.|. .. |.....| ..|.....
pnkskeqygeifveiveekqyanlkirtfkltkkivalteqekqvkaetRivklfqlteWeledkvPlstnalielrrrvrlwrekvdedpeegPvvvvs
SNMIGRSAVFCAAMATVDQMKSSSVVDVFQTVKNMRVNLPGAVQNKGQYKMIHTLAAAYV
|. .|| |..|. |...... ||||. || .| . |. |.|. .|| | . .|
sdGasRsGvylaidanlelvekeeevdvFeavktlrrsRpqLvenveeYkyiYdvlleav
|
|||||||||
subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 268-511 | 6.3e-47 | 155.3 | In-house | 32-287 (325) | alignment | ||
Range on Protein: 268-511
Range on HMM: 32-287/325.0
VPPQDAVCDVA---RQHPRKNRYQEILPTDQWRVHLKS----ESPDYINAVFIPSYKNDKGFIIAQSPLRETRRDFWKMIFDREiTTIVMLSPIMEGEEE
.|..|.. . . |||...... |. || |.. | ||||| .. ..|. . |. ||.|| .| |.|....| . ...|.. .......
lpsddgiakkvamkpenkaknrfknvvaldksrvvletkkddpssdyinasylrddkkkdvflaaqaPltatindlWrlvldWr.csvvvvlneldlgkd
ACAQYWPKE--GTIEFGEFTISVREEWGHQSFSRKLLLIRNNKNNMLRRLAHFQVDGWSNDDITScNEGAIINTMNLVKTLQRK-----SPNSPILMHCS
||.||||| . .|| . ...| . . | ... |. | . ||. .| . ..|. ..|||... . .|||.|||
rcavywpkemgksktfGglevklrtieeisdyvhrvldvkqvkkGetrsvkqfqlqswddmGvqk.rpatlisilqlvkavservtantkastpilvhcs
NMIGRSAVFCAAMATVDQMKSSSVVDVFQTVKNMRVNLPGAVQNKGQYKMIHTLAAAY
. .||. || . . .... | ||.|. ||..| . | |. || .|.. . .
aGvGrtGvfislysalakvieesrvdifgfvkklrkdrpsmvetvdqyiliyealvea
|
|||||||||
subfamily_PTPN3_pd | Subfamily PTPN3 | 280-506 | 1e-46 | 154.2 | In-house | 40-270 (280) | alignment | ||
Range on Protein: 280-506
Range on HMM: 40-270/280.0
QHPRKNRYQEILPTDQWRVHLKSESPDYINAVFI----PSYKNDKGFIIAQSPLRETRRDFWKMIFDREITTIVMLSPIMEGEEEACAQYWPKE-GTIEF
. ||||..||| |. ||.||... ||||| .. || . . .|..| ||..| |||.|........|||| ..| | ||||.. ..|.
enlsknryrdilpydatrvklkesetdyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqksslivmlttlverGrvkChqyWPetedeley
GEFTISVREEWGHQSFSRKLLLIRNNKNNMLRRLAHFQVDGWSNDDITSCNeGAIINTMNLVKTLqRKSPNSPILMHCSNMIGRSAVFCAAMATVDQMKS
|||.. ...| ..|. . |........ |.. ..| |.. .. . . ... .. |..| |.. ..|...||| |||. |. . .. . .
gefsvkcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPdds.adflefvervrkl.rsgkeePvvvhCsaGigrtGvlilletalaliea
SSVVDVFQTVKNMRVNLPGAVQNKGQYKMIH-T
. | . . |..|| ||...|||.. .
aepvypldivrtmrdqramlvqtasqykfvCea
|
|||||||||
subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 249-513 | 1.3e-46 | 154.0 | In-house | 10-277 (281) | alignment | ||
Range on Protein: 249-513
Range on HMM: 10-277/281.0
DNASVTGFEAQFNVLEQVSVPpQDAVCDVARQHPRKNRYQEILPTDQWRVHL----KSESPDYINAVFIPSYKNDKGFIIAQSPLRETRRDFWKMIFDRE
.. . .|| ... |... | . |. | . ||||. | |. ||.. .... ||||| |.|.||..|..|..|.|. .. .||.|.....
sqndnaGfieeyeklaaigvd.ntataskadenvlknrYsnivaYDatrvkvtpneenkntDYinanfvpgykgekeyiatqgPvPaslvafWqmvweqk
ITTIVMLSPIMEGEEEACAQYWPKEG-TIEFGEFTISVREEWGHQSFSRKLLLIrNNKNNMLRRLAHFQVDGWSNDDITScNEGAIINTMNLVKTLQRKS
...|||. .|.. | .||| . ....|..|.. .| .... .. . . ..... |...... | . . . . .... . |. |..|.
vsaivmvtreieagklkChrYWPddnselkygdvtvkstaeeekatyierkfkl.eresgetreveqlaytaWPdhGvPa.ttkellefrkevlkltekk
PNSPILMHCSNMIGRSAVFCAAMATVDQMKSS-SVVDVFQTVKNMRVNLPGAVQNKGQYKMIHTLAAAYVN
. |...||| .||. .. | |...... . .|| ..|...| . || ||. .. ...
tkaplvihCsaGvGrtGtyialDrlvkaveaeleeldvkavvaelrkernlmvqtvvqyefvykavldald
|
|||||||||
subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 252-520 | 1.8e-46 | 153.2 | In-house | 13-301 (301) | alignment | ||
Range on Protein: 252-520
Range on HMM: 13-301/301.0
SVTGFEAQFNVLEQVSvpPQDAVCDVARQHPRKNRYQEILPTDQWRVHLKSE------SPDYINAVFIPSYKNDKGFIIAQSPLRETRRDFWKMIFDREI
..||.|.. |.... .. .. . .. . ||...| . |. |. || . . .|||| .| .|.. | ||.||.|...| .|||..|..
hsnkfeeqykelkege..dksctvglseenkalnrfknitvyddnriilkpkpnldlcqreyinasyidgysekkkfiaaqgpmkktlvdfWrliwqekp
TTIVMLSPIMEGEEEACAQYWPK--EGTIEFGEFTISVREEWGHQSFSRKLLL--IRNNKNN-------------MLRRLAHFQVDGWSNDDITScNEGA
..|||. || .. | ||||. . . |||.||. . .| . .| . | |.. || . . .|| | .| . .
vsivmvtnlkegtkskceqywpnseaeseefgpftvtlvneqvyPdfvirqlnvkiqdgsnngyierkfkvksdksswdvlqlqvtdWpqdGvvr.eprt
IINTMNLVKTLQRKSPNSPILMHCSNMIGRSAVFCAAMATVDQMKSSSVVDVFQTVKNMRVNLPGAVQNKGQYKMIHTLAAAYVNLFSTSAN
... .. | |.| .|.. |||. ..|| |.|. ...| |. |||||| .| .| . ||||. || .|. |..| || ||
vLqviddvihrqqkigggpvvVHCSdtVsrsGvYcsvsiglEQckaegVVdvfqvtkavrrskpgaVtTLeqytsiydvidmylqlnstyan
|
|||||||||
subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 271-506 | 1.8e-46 | 153.9 | In-house | 15-249 (284) | alignment | ||
Range on Protein: 271-506
Range on HMM: 15-249/284.0
QDAVCDVARQHPRKNRYQEILPTDQWRVHLKS----ESPDYINAVFIPSYKNDKGFIIAQSPLRETRRDFWKMIFDREITTIVMLSpimegeEEACAQYW
| | |||. .||. |. .| |. | ||||| || |.. . .| .| || .| |||.||.. ...|||.|. .. |.|||
tdqtfanldqnkdknrighilafdknvvklerliGeefsdyinasfitGyqrkdkyiatqGPldntladfWrmiweyncstivllt......kdkcsqyw
PKEGTIEFGEFTISVREEWGHQSFS-RKLLLIRNNKNNMLRRLAHFQVDGWSNDDITSCNeGAIINTMNLVKTLQRK-SPNSPILMHCSNMIGRSAVFCA
|... |. ..| ..| . . |.. | .. |.. |.. | || . . .. .. |. |..| ...|..||| .||. |. .
plkivikeerfkvkvdsveeseeyvvrdielsedgkekdirkirqfhflgwpdvgvpdyp.sdlmrlvkkvrhltskenhranivvhcsagvgrtgvyiv
AMATVDQMKSSSVVDVFQTVKNMRVNLPGAVQNKGQYKMIHT
. .|.|| . |||...|...| . . ||. |||.|..
ldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiys
|
|||||||||
subfamily_PTPN6_pd | Subfamily PTPN6 | 6-223 | 6.3e-46 | 151.8 | In-house | 94-294 (306) | alignment | ||
Range on Protein: 6-223
Range on HMM: 94-294/306.0
DEQSQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSRGS-EDYGPFTVTLQKETTSNSFIIRELTLHYNtmmgnlrskivnpt
.....|||||| |. || |||||||||.. |||.|| | . ||..|||. . |.|| .|| .|.. ...|.|||... .
kgsdksyiatqgclettvsdFWrmvwqensrvivmttkevErgkekCarYWPdeeekeeyGkisvtnvseksladYilRelsvskk..............
gridpnkkeyySSAQSTLLITHYQFIDWLEYGPQPPINSLVKFNKIISNQTEHK----KGPIVVHCSTGGGRTGAFIGMSCS---IKDALTESIIDIPAV
...... . .|.| .| . | . . ...| . .....|. .|||||||| | ||||.|| . . |. .. ||| .
...........kkkkeerevfqyhfksWPdhgvpkdpgavLdfledvnrkqeeleeaeagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqkl
VTIMREQRMMMIQTLDQYMLVHEAVL
| ..|||| ..|| .|| .|..|.
vksvreqrsglvqteqqykfvykaik
|
|||||||||
subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 9-251 | 1.5e-44 | 147.1 | In-house | 86-302 (315) | alignment | ||
Range on Protein: 9-251
Range on HMM: 86-302/315.0
SQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSR--GSEDYGPFTVTLQKETTSNSFIIRELTlhyntmMgnlRskivnptgr
. |||.||||. .| ||||||.|||. .|||.||.||. .||| |||| | | ..| . |.| . . ..|.|. . |
dkayiasqgPlkasvddfwrmvlqekvttivmvtkkqegdkikcrqywPdrkadsvefGsikvellsleadtdgvarklv......t...r.........
idpNKKEYYSsaqstllITHYQFIDWLEYGPQPPINSLVKFNKIISNQTEHKKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMREQRM
. .|. .| .|| .| . | . ||.|. | . . ..|. ...||||.| |||| .| . .... .. .|. .|...|..|.
...kseesrt.......vtqfqftewPdkGvdkqtssllklikevkadngkkefsllvhcsaGvGrtGvvisidevvaqikrtrsvdvfnfvknlrakrp
MMIQTLDQYMLVHEAVLEQALCGDTQIVACDLQNTISSLSSSDNA
..|| ..| ....||||. | .| |. . . . | .| ..
ylvqteeeyafiydavledllwrntlilvihftdhlqdlhtsvdg
|
|||||||||
subfamily_PTPN6_pd | Subfamily PTPN6 | 231-513 | 1.7e-44 | 147.0 | In-house | 2-298 (306) | alignment | ||
Range on Protein: 231-513
Range on HMM: 2-298/306.0
TQIVACDLQNTISSLSSS-DNASVTGFEAQFNVLEQVSVPPQDAVCDVAR-QHPRKNRYQEILPTDQWRVHLK---SESPDYINAVFIP--SYKNDKGFI
|...| .... .| |. . .. . .||| .|. |.| . . . |. . .||||. ||| |. || || ||||| .| . ..|| .|
tsllakeieqrvselekeeeslekagfeeefeelqqeeakkllsrkegakpenkeknryknilPfDhtrvilkepsvpgsdyinanyikkevkgsdksyi
IAQSPLRETRRDFWKMIFDREITTIVMLSPIMEGEEEACAQYWPKEGT-IEFGEFTISVREEWGHQSF-SRKLLLIRNNKNNMLRRLAHFQVDGWSNDDI
.| |..| |||.|... . . |||. .| .| ||.|||.| . |.|. ... .| .... |.|.. ...|.. |.. ... | . ..
atqgclettvsdFWrmvwqensrvivmttkevErgkekCarYWPdeeekeeyGkisvtnvseksladYilRelsvskkkkkkeerevfqyhfksWPdhgv
TScNEGAIINTMNLVKTLQRKSP---NSPILMHCSNMIGRSAVFCAAMATVDQMKSS---SVVDVFQTVKNMRVNLPGAVQNKGQYKMIHTLAAAYVN
. . ||... .. |.. |... . ||..|||. ||| | . ....... .|. ..|| .| | || . |||.... ..|..
pk.dpgavLdfledvnrkqeeleeaeagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqteqqykfvykaikkyie
|
|||||||||
subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 6-224 | 4.1e-44 | 145.6 | In-house | 41-237 (237) | alignment | ||
Range on Protein: 6-224
Range on HMM: 41-237/237.0
DEQSQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSRG-SEDYGPFTVTLQKETTSNSFIIRELTLHYNTMMGnlrskivnpt
| .||||.||||. . |||.|||||| ||||| | | ..|| .|||| . || .||.|.|. . .| |.| ... .
dgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpstdqpaaygvltvslkkkeefsdytvrslllskrltlk..........
gridpnkkeyyssaqSTLLITHYQFIDWLEYGPQPPINSLVKFNKIISNQTEH--KKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMR
|| ||| | . | .|..| | | |...| . || ..|||.| |||| |. . . ...| . ..|| | .
...............evrlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlrqakekkvvdiynyvysie
EQRMMMIQTLDQYMLVHEAVLE
|.| .||| |||...|...||
edrpyiiqtkdqyvfihqtile
|
|||||||||
subfamily_PTPN13_pd | Subfamily PTPN13 | 270-506 | 2.2e-43 | 143.5 | In-house | 25-263 (273) | alignment | ||
Range on Protein: 270-506
Range on HMM: 25-263/273.0
PQDAvCDVARQ--HPRKNRYQEILPTDQWRVHLKSESPdYINAVFI--PSYKNDKGFIIAQSPLRETRRDFWKMIFDREITTIVMLSPIMEGEEEACAQY
|.| |.|... . .||||...|| |. ||.|..|.. |||| .| | |. .|..| || || .|||.|..... . |.|.. |... | .|
pldt.cevgkkkenkdknryrnvlPydetrvklgdegg.yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvkchry
WPKEG--TIEFGE-FTISVREEWGHQSFSRKLLLIRNNKNNMLRRLAHFQVDGWSNDDITSCNEgAIINTMNLVKTLQRksPNSPILMHCSNMIGRSAVF
||.. .. . ..... . ...|. . | ..... . |..||.. | . .. | . ... . |..||. ..||..||| |||| ..
wPesknkklkvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaa.ellqfvaevrrlqt..dagPivvhcsaGiGrsGtl
CAAMATVDQMKSSSVVDVFQTVKNMRVNLPGAVQNKGQYKMIHT
. . .. .. .|| ..|...| | || | || ...
itidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvyk
|
|||||||||
subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 270-514 | 2.7e-43 | 142.9 | In-house | 10-266 (270) | alignment | ||
Range on Protein: 270-514
Range on HMM: 10-266/270.0
PQDAVCDVARQHpRKNRYQEILPTDQWRVHLKSESP----DYINAVFIPSY-KNDKGFIIAQSPLRETRRDFWKMIFDREITTIVMLSPIMEGEEEACAQ
.... ..||.. . |||..|||. . || |.... |||| ... . ...| .| |..|| | ..||.||.... |.|||.....| . |..
sesdlpeaargk.klnRyadiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCer
YWPKEG----TIEFGEFTISVREEWGHQSFSRKLLLIRnnKNNMLRRLAHFQVDGWSNDDITSCNE-----GAIINTMNLVKTLQRKSPN-SPILMHCSN
|||.| ..|.|. .. . .| .. . .. | .. .. ||| ||. | .. . . .. ...... |. ... . .|.|.|||.
YWpaepkekvkledgkikvlalseekeegyiltrlrle..ekgeerrlvHfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcsa
MIGRSAVFCAAMATVDQMKSSSVVDVFQTVKNMRVNLPGAVQNKGQYKMIHTLAAAYVNL
.||. .. | .| ..... ||| . ....| . . || ||.... . |..
GvgRtGtlialDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyeflykavveyaer
|
|||||||||
subfamily_PTPN1_pd | Subfamily PTPN1 | 7-230 | 4.8e-40 | 132.1 | In-house | 68-277 (290) | alignment | ||
Range on Protein: 7-230
Range on HMM: 68-277/290.0
EQSQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSRGSE-----DYGPFTVTLQKETTSNSFIIRELTLHYntmmgnlrskiv
| ..|| ||||| .|| ||.|||..|. |.||| |. | .||| ||||. .| . ..|.| .| ... ...| | |.
eakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvvekeqikcaqywPqgeeekellledtklkvkliseerksyytvrllelen............
nptgridpnkkeyySSAQSTLLITHYQFIDWLEYG-PQPPiNSLVKFNKII--SNQTEHKKGPIVVHCSTGGGRTGAFIGMSCS---IKDALTESIIDIP
..| | |.|. .. | ..| |. | ....|| . | ...|| |.|||.| ||.|.|. . . |.. | .||
..............lktqetreilhfhyttwpdfgvpesp.aaflkflfkvresGslssdvGpavihcsaGiGrsGtfclvdtclvliekkddlssvdik
AVVTIMREQRMMMIQTLDQYMLVHEAVLEQAL--CGD
|. .|..|. .||| || . . |.|| | ||
kvllelrkyrlGliqtadqlrfsylaileGakvikgd
|
|||||||||
subfamily_CG7180_pd | Subfamily CG7180 | 9-230 | 7.4e-39 | 128.1 | In-house | 84-294 (296) | alignment | ||
Range on Protein: 9-230
Range on HMM: 84-294/296.0
SQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRiKCSQYWPSRGSEDYGPFTVTLQKETTSNSFIIRELTLHYNtmmgnlrskivnptgrID
..|| |..| ..|| .|||.|..|.. |.|.||| . . .. .||| .. |.||.. | . .| . . ||.. | . |
kkeyivteapkketvdefWrlvydeeisavvvLtktfdfak.mypsywpnkskeqygeifveiveekqyanlkirtfkltkk................iv
PNKKEYYSSAQSTLLITHYQFIDWLEYGPQPPI-NSLVKFNKIISNQTEH-----KKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMR
.. | .....|. | | . |.|... . . |. ..||.||..| |..|.|..... .. . | .|. | .|
alteqekqvkaetRivklfqlteWeledkvPlstnalielrrrvrlwrekvdedpeegPvvvvssdGasRsGvylaidanlelvekeeevdvFeavktlr
EQRMMMIQTLDQYMLVHEAVLEQALCGD
..| .... ..|. . . .|| ||.
rsRpqLvenveeYkyiYdvlleavlcnk
|
|||||||||
subfamily_PTPN1_pd | Subfamily PTPN1 | 276-502 | 1.3e-38 | 127.4 | In-house | 25-261 (290) | alignment | ||
Range on Protein: 276-502
Range on HMM: 25-261/290.0
DVARQHP--RKNRYQEILPTDQWRVHLKSESPDYINAVFIPSYKNDKGFIIAQSPLRETRRDFWKMIFDREITTIVMLSPIMEGEEEACAQYWPKEG---
.|... .|||... | | |..|.... ||||| .. . .. .|..| || .| ||.|..... ..||| ..| |. ||||||..
reaklpenrnlnryrdvspydhsrikleradndyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvvekeqikcaqywPqgeeek
TIEFG--EFTISVREEWGHQSFSRKLLLIRNNKNNMLRRLAHFQVDGWSNDDITSCNeGAIINTMNLVKTLQRKSP-NSPILMHCSNMIGRSAVFCA---
.... .... . .| .. . ..|| . | | . | . || |.. . .. .| .. . |. |. | ..||| |||| ||
ellledtklkvkliseerksyytvrllelenlktqetreilhfhyttwpdfgvpesp.aaflkflfkvresGslssdvGpavihcsaGiGrsGtfclvdt
AMATVDQMKSSSVVDVFQTVKNMRVNLPGAVQNKGQYK
.. ... . | ||. ... ..| | .| . | .
clvliekkddlssvdikkvllelrkyrlGliqtadqlr
|
|||||||||
0051429 | (Phosphotyrosine protein) phosphatases II | 10-225 | 6.7e-37 | 123.0 | In-house | 22-224 (272) | alignment | ||
Range on Protein: 10-225
Range on HMM: 22-224/272.0
QKYIATQGPLDRTVVDFWRMvWQEKACAIVMLTKLQEDLRIKCSQYWP------------SRGSEDYGPFTVTLQKETTSNSFIIRELTLHYNTMmgnlr
......|||. |. ||||. .... .||.|... | | ||..||| | . || ..|||..|.. . .|.|||.|..
grlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseellldyilrellltllls.....
skivnptgridpnkkeyyssAQSTLLITHYQFIDWLEYGPQPPInsLVKFNKIISNqtehkKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIID----
|. .. ..|....||. .| . |... ... . .||..|||| | .||| .. . .. . | |.|
....................agearevmhlhytdwpdhgvpqea..llellellld.....ggpvlvHCsaGkdRTGtvvallllllgvsletivddYll
----IPAVVTIMREQRMMMIQTLDQYMLVHEAVLEQ
. ..| .|.||. ..|| .||. ..||.||
tnlyleeaveelraqrpgavqteeqylflyeallel
|
|||||||||
subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 254-512 | 8.7e-37 | 121.6 | In-house | 6-259 (267) | alignment | ||
Range on Protein: 254-512
Range on HMM: 6-259/267.0
TGFEAQFNVLEQVSVPPQDAVCDVARQHPRKNRYQEILPTDQWRVHLKSESPDYINAVFIPSYKNDKGFIIAQSPLRETRRDFWKMIFDREITTIVMLSP
. .| .|. ....| . . .| . .||... || |. || |. . .|||| .. .|| . ||. | ||. | ||...| |.....||.| .
ceiekefelikkisdtsstisqsiaeknqernrlddnlpyddtrvilrtkeeeyinasyvegyktknafivtqdplkntitdfltvihdqkvpvivlltk
IMEGEeeaCAQYWPKE--GTIEFGEFTISVREEWGHQSFSRkLLLIRNNKNNMLRRLAHFQVDGWsndDITSCNEGAIINTMNLVKTLQRKSPNSPILMH
. ... ..|| . . .. ..|. | . . . | . ||. . .. . | .| . |. . . .. | . | |....
vftdn...irlfwPPkmgqakkyqdltvehslekeendyqi.itlelkfknesahnvtlyyykkw...nintnnkpylkplfgilaknqlengnrPlvva
CSNMIGRSAVFCAAMATVDQMKSSSVVDVFQTVKNMRVNLPGAVQNKGQYKMIHTLAAAYV
||. .||| | . . ....| .|.|.|. ....| .| |. | .| || | | |
csdGvGrsGtflvidsqleraktegvsdifdflrkirsqriglvdtkeryiyihellaeya
|
|||||||||
0041856 | (Phosphotyrosine protein) phosphatases II | 9-231 | 5.8e-36 | 119.2 | In-house | 33-176 (182) | alignment | ||
Range on Protein: 9-231
Range on HMM: 33-176/182.0
SQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTklqedlrikCSQYWPsrgsedygpftvtlqkettsN-Sfiireltlhyntmmgnlrskivnptgri
....|||||||..|| ||.||..... .||.|| . .||| .
atrfiatqgpllstvadflrmlkelgittivnlt.........eelywp....................ell............................
dpnkkeyyssaqsTLLITHYQFIDWLEYGPQPpINSLVKFNKIISNqtehKKGPIVVHCSTGGGRTGAFIGMSCSIKDalteSiIDIPAVVTIMREQRMM
. |...|... | .|. . ...|..| ... . ..||..|||| | ||||..... .| . .... .| .|..|..
.............erlgiqylylpwpDhgvpd.ldelldfieevle....eggpvlVHCsaGvgRtgtlvaaylmkkl....g.vsleeavklvrsrRpg
MIQTLDQYMLVHEAVLEQALCGDT
|..|..|| ... |.|| |...|
mvitpnqyfflqlallellllkkt
|
|||||||||
subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 283-506 | 5.9e-36 | 118.9 | In-house | 5-233 (237) | alignment | ||
Range on Protein: 283-506
Range on HMM: 5-233/237.0
RKNRYQEILPTDQWRVHLKSE--SPDYINAVFIPSYKN-DKGFIIAQSPLRETRRDFWKMIFDREITTIVMLSPIMEGEEEACAQYWPKE-GTIEFGEFT
|||| .| |. || || . ||||| .. .. | .| || || . |||.|... . ||||. ..||.|. | .|||. .| .|
iknrygnivaydhsrvvlkgagsgsdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpstdqpaaygvlt
ISVREEWGHQSF-SRKLLLIRNNKNNMLRRLAHFQVDGWSNDDITSCNEGAIINTMNLVKTLQRKSPNSPILMHCSNMIGRSAVFCAAMATVDQMKSSSV
.|.. . . | ||| .. . . .| . .| | . . . |... . | .| ..||| .||...| | . | | |
vslkkkeefsdytvrslllskrltlkevrlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlrqakekkv
VDVFQTVKNMRVNLPGAVQNKGQYKMIHT
||... |... . | .| | || .||
vdiynyvysieedrpyiiqtkdqyvfihq
|
|||||||||
0036282 | (Phosphotyrosine protein) phosphatases II | 9-220 | 1.1e-35 | 118.2 | In-house | 16-164 (174) | alignment | ||
Range on Protein: 9-220
Range on HMM: 16-164/174.0
SQKYIATQGPLDrtvvdFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSrgsedygpftvtlqkettsnsfiireltlhyntmmgnlrskivnptgrid
. ..||.||||. ||.|..... ..|||....|. . || .|||.
tprliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe..................................................
pnkkeyySSAQSTLLITHYQFIDWLEYGPQPPINsLVKFNKIISNQTEH-KKGPIVVHCSTGGGRTGAFIGMSCSIKDALtESIIDIPAVVTIMREQRMM
. . |. .|... | .|. . | .| |.. . .. ..||..|||| | ||||..... .. | || .|. ..| .| ||..
.......lredlerlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpg
MIQTLDQYMLVHE
|.|| .||. ...
mvqtpsQyrflyy
|
|||||||||
0046846 | (Phosphotyrosine protein) phosphatases II | 10-224 | 1.5e-35 | 117.9 | In-house | 23-171 (176) | alignment | ||
Range on Protein: 10-224
Range on HMM: 23-171/176.0
QKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSRGSEDYgpftvtlqkettsnsfiireltlhyntmmgnlrskivnptgridp
..||||||| ||. ||..|..... |.|.||...| |.|| .||| ....
srpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgi.............................................
nkkeyyssaqstllitHYQFIDWLEYGPQPPiNSLVKFNKIISNQTEHKkGPIVVHCSTGGGRTGAFIGMScsikdaLTES--IIDIPAVVTIMREQRM-
.|....| ..|. . . | .. ..| .. ... ||..|||| | ||||... . | |. ... .. .||||.
................qylhlpwpDhgvpdl.elllellefirealkeg.gpvlVHCsaGigRtgtlvaay......llelekglsveealalvreqRpl
MMIQTLDQYMLVHEAVLE
...|| .|| ..|..|.
gavqtpeQyrflyefell
|
|||||||||
subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 9-254 | 3.4e-35 | 116.2 | In-house | 87-264 (392) | alignment | ||
Range on Protein: 9-254
Range on HMM: 87-264/392.0
SQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLrikcsqywpsrgsedygpftvtlqkettsnsfiireltlhyntmmgnlrskivnptgrid
. |||.||| .. ||||||.||....|.|.|||.|
ekayiasqgpnaaslddfwrmvfqenvttiamvtklkegd............................................................
pnkkeyysSAQSTLLITHYQFIDWLEYGPQPPINSLVKFNKIISNQTEHKKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMREQRMMM
... .. ..| .| . . .||.|| | .. . . |...|||.| |||| | . . . | . ..|. .|| .|..| .|
........kgddartvaqfhftewPdkdvpkhtssllkfikevkadfGqythpliihcsagvgrtgvvisidsvvahakktrmvdvfnfvtnirrkrpym
IQTLDQYMLVHEAVLEQALCGDTQIVACDLQNTISSLSSSDNASVT
.|| .|| ... ||||. | .| | . . .. ||.| . |.
vqtkeqyafiygavledllwrntlipvvhftdhlqdlstssdGdvr
|
|||||||||
subfamily_PTPN14_pd | Subfamily PTPN14 | 262-513 | 7.9e-35 | 115.3 | In-house | 28-297 (300) | alignment | ||
Range on Protein: 262-513
Range on HMM: 28-297/300.0
VLEQVSVPPQDAVCDVARQ--HPRKNRYQEILPTDQWRVHLK---SESPDYINAVFIP--SYKNDKGFIIAQSPLRETRRDFWKMIFDREITTIVMLSPI
|... .||....|. .|||....|| .. ||.|. .| .|||| | ... .|.||.||. | .|||.|... ... |||| .
eyeripkkredallstaklpenaeknrfkdvlPyednrvelsptkenstgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivmltee
MEGEEEACAQYWPKE----GTIEFGEFTISVREEWGHQSFSRKLLLIRNNKNNMLRRLAHFQVDGWSNDDITSCNEGaIINTMNLVKTLQRK--------
|. | . .|.||. |.|||.| .. . .|. . | .. . | . |.| |..... . .| .. .. |. ..||
eedgkeksfkyfPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkg.flsyLeevqsvrrktnsevesk
SPNSPILMHCSNMIGRSAVFCAAMATVDQMKSSSVVDVFQTVKNMRVNLPGAVQNKGQYKMIHTLAAAYVN
. . |.|.|||. .||. | . . .. ..|. .... .| ||. .|||..... |..
eskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLreqrmllvqtlaqYkfvYkvlikylk
|
|||||||||
0049260 | (Phosphotyrosine protein) phosphatases II | 9-220 | 1e-34 | 114.8 | In-house | 8-144 (152) | alignment | ||
Range on Protein: 9-220
Range on HMM: 8-144/152.0
SQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWpsrgsedygpftvtlqkettsnsfiireltlhyntmmgnlrskivnptgrid
....||||||.. |. |||||... .. .|||||.|.|. ..|| ||.
pfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi....................................................
pnkkeyyssaqstllitHYQFIDWLEYGPQPPINSLVKFNKIISNQTEHKKGPIVVHCSTGGGRTGAFIGMSCSIkdalteSIIDIPAVVTIMREQRMMM
.|... | .|... . | ....| ..|.||..|||| | ||||... . . ... .| .||.|...
.................qylhlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpga
IQTLDQYMLVHE
... .|.....|
vpnpgqlrflye
|
|||||||||
subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 282-505 | 1.1e-34 | 114.4 | In-house | 55-276 (290) | alignment | ||
Range on Protein: 282-505
Range on HMM: 55-276/290.0
P--RKNRYQEILPTDQWRVHLKSESP-DYINAVFIPSYKNdkGFIIAQSPLRETRRDFWKMIFDREITTIVMLSPIMEGEEEACAQYWPK-EG-TIEFGE
. .||||... |. || || . ||. | .. | ||..| .|..| |.|.|. . ....|||| ..| |.||.|. || .. |||
tefkknrykdvvcndktrvilkdGydGdyvhanyvkGlka..mfiltqGalkdtvidiwrmvlqekvaaivmlceliedGkakceqyypekeGevltfGe
FTISVREEWGH-QSFSRKLLLIRNNKNNMLRRLAHFQVDGWSNDDITSCNeGAIINTMNLVKTLqrkspNSPILMHCSNMIGRSAVFCAAMATVDQMKSS
.|. || . . .|.| .|. .. .| |... | . .. . |.. |. .... . |. .||| |||. | | .... .
itvlcseeddkdaniikktlsvrdkdsGkehklkhlkikswpdksvalst.lallrtlrilrka.....sGpvvvhcsaGiGrtGtfvaievglqilldG
SVVDVFQTVKNMRVNLPGAVQNKGQYKMIH
.|. ..|. .| ..|| || ..
keldlldlvralrnsrlnsvqvdiqylalv
|
|||||||||
subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 282-511 | 1.1e-34 | 114.5 | In-house | 39-276 (287) | alignment | ||
Range on Protein: 282-511
Range on HMM: 39-276/287.0
PRKNRYQEILPTDQWRVHLKSE---SPDYINAVFIPSYKNDKGFIIAQSPLRETRRDFWKMIFDREITTIVMLSPIMEGEEEACAQYWPK-EGTIEFGEF
.|||| ..|| |. || | | ||||| ...||..|. || ||.|. | ||||....... ....... .| | .|||. | . | .
vkknryadvlPiddtrvllsaegelGsdyinanyvasytddeafiaaqgPiaatvrdfwravletrsasvitmtreveearlkcykywPerevPmrvGGy
TISVREEWG-HQSF-SRKLLLIRNNKNNmLRRLAHFQVDGWSNDDITSCNEGAIINTMNL--VKTLQRK-SPNSPILMHCSNMIGRSAVFCAAMATVDQM
.. . . . . | | || . .. | . ... | .. .. | | ... |.|. | |...|.. |||| .. | .. |...
svvlldydikePeygvralrlidletre.arvvkqldllswPdkvlaPtavglirfvldvkqhielardasevGPlvvhddvGiGrsGillatlvlvsrl
KSSSVVDVFQTVKNMRVNLPGAVQNKGQYKMIHTLAAAY
.. ||| ..| .| . || |.... ..|
edlGrvdvaavvirlreyraalvqavvqlrllyealvty
|
|||||||||
subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 10-237 | 1.6e-34 | 114.2 | In-house | 91-290 (439) | alignment | ||
Range on Protein: 10-237
Range on HMM: 91-290/439.0
QKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRikcsqYWPSRGSEDYGPFTVTLQKETTSNSFIIRELtlhyntmmgnlrsKIVNptgRIDP
. ||||||| . |. ||||.|...|. |||||.| | . |||| . || .| ... ..|| . |..| . |
klyiatqgpkkettddfwrlviekktvtivmltnlvesyk.....ywpsdaevcygdiavrvdrnielpnyvirgf.............kvfn...erdt
NKKEyyssaqSTLLITHYqfIDWLEYGPQPPINSLVKF-NKIISNQTEHKKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMREQRMMM
..|| |.| || | | . ...| | | . ... ||.|||||.| ||||. | . .... .| .|| .|...|.|| |
teke......rtvlqfhy..iawpdknvpaqashvldflrainsandkeeygpvvvhcsagvGrtGtiialdialeqlklenkvdikgivkvlrkqrkqm
IQTLDQYMLVHEAVLEQALCGDTQIVACD
.|.| ||.....||||. ||. .. .
vqalcqyvfiynavledivyGdiavtide
|
|||||||||
0036282 | (Phosphotyrosine protein) phosphatases II | 306-505 | 6.9e-34 | 112.4 | In-house | 3-163 (174) | alignment | ||
Range on Protein: 306-505
Range on HMM: 3-163/174.0
DYINAVFIPSYKNDKGFIIAQSPLRetrrdFWKMIFDREITTIVMLSPIMEGEEEACAQYWPKegtiefgeftisvreewghqsfsrklllirnNKNNML
||||| .. . ...|. | ||. ||.|... |||.||| . .| . . | .||| ... .
dyinaspldlsyitprliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe...............................lredle
RRLAHFQVDGWSNDDITSCNEgaIINTMNLVKTLQRKSPNSPILMHCSNMIGRSAVFCAAMATVDQMKsSSVVDVFQTVKNMRVNLPGAVQNKGQYKMIH
| ... .| . . .. ... ...|.. . ..|. |.| ||| .||.....||. ... .|.||....|. .| ||.||. .||. ..
rlgiqylylpwpDhgvpdlsi..llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtpsQyrfly
|
|||||||||
0043147 | (Phosphotyrosine protein) phosphatases II | 10-220 | 1.3e-33 | 111.6 | In-house | 20-155 (172) | alignment | ||
Range on Protein: 10-220
Range on HMM: 20-155/172.0
QKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLqedlrikcsqywpsrgsedygpftvtlqkettsnsfiireltlhyntmmgnlrskivnptgridp
...|||||||..|. |||||..... .||.||.|
drfiatqgplrntladfwrmlkelgithivnltel.................................................................
nkkeYYSSAQSTLLITHYQFIDWLEYGPQpPINSLVKFNKIISN-QTEHKKGPIVVHCSTGGGRTGAFIGMSCSIkdaltE-SiiDIPAVVTIMREQRMM
.| . . |. .|... | .|.. ... | .| ..| . . . ..||..|||| | ||||... . . . .. .| .||.|..
....lydpellerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml.....lgl..sleeavalvrekRpg
MIQTLDQYMLVHE
..|. .||.....
avqnpsqyrflyy
|
|||||||||
subfamily_PTPRN_pd | Subfamily PTPRN | 257-513 | 1.3e-33 | 111.0 | In-house | 32-293 (297) | alignment | ||
Range on Protein: 257-513
Range on HMM: 32-293/297.0
EAQFNVLEQVSVPPQDAVCDVARQHPRKNRYQEILPTDQWRVHLKSES----PDYINAVFIPSYKN-DKGFIIAQSPLRETRRDFWKMIFDREITTIVML
|.... | . |. . | . .|||....|| |. ||.||.|. ||||| .| .| .|.|| .| |||.|.... .. ||.|
ekewealcayeaepstkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplastvadfwqmvweqGvvvivnl
SPIMEGEEEACAQYWPKEGTIEFGEFTISVREE--WGHQSFSRKlLLIRNNKNNMLRRLAHFQVDGWSNDDITSCNEgAIINTMNLVKTLQRKsPNSPIL
... | . ..|..|||.||. .. . . . | | .. . | . ..| ... | .. | | . .. . .... | | .||.
trleeegvkqckrywpdeGsevyhiyevhlvsehiwcddylvrs.fylknlqtsetrtvtqfhflswpeegvPasak.sllefrrkvnksyrG.rscpiv
MHCSNMIGRSAVFCAAMATVDQM-KSSSVVDVFQTVKNMRVNLPGAVQNKGQYKMIHTLAAAYVN
.|||. ||. |... .... | .|. |.. .| . || |. | |.... | | ||
vhcsdGaGrtGvyilidlvlnrllkGvkeidiaatlehlrdqrpglvktkdqfefaltavaeevn
|
|||||||||
subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 121-257 | 5.9e-33 | 109.3 | In-house | 177-315 (319) | alignment | ||
Range on Protein: 121-257
Range on HMM: 177-315/319.0
TLLITHYQFIDWLEYGPQPPINSLVKFNKIISNQTEH-KKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMREQRMMMIQTLDQYMLVH
| ..|.|. .| . . ||... | | . .|. ..|||||||| | ||||.|| .. . |...|. .| .| || .|.|. .|| ...
tRevkhfqyteWpdhdvPekatslldllkrirksrektqsgPivvhCsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiy
EAVLEQALCGDTQIVACDLQNTISSLSSSDNAS-VTGFE
||.|| . .|||.| ||.. . .|.. . . ||.|
ealleaveagdteievqdlrdrlkqlaekvadtgetgle
|
|||||||||
0051429 | (Phosphotyrosine protein) phosphatases II | 305-514 | 1.8e-32 | 108.4 | In-house | 4-227 (272) | alignment | ||
Range on Protein: 305-514
Range on HMM: 4-227/272.0
PDYINAVFIPSYKN---DKGFIIAQSPLRETRRDFWKMiFDREITTIVMLSPIMEGEEEACAQYWP------------KEGTIEFGEFTISVREEWGHQS
..|||| ... | . .. .. .. ||. | .|||.. . |.|||.| . .| . . | .||| . ||..| ... . .|. .
sgyiNardvggygrvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseellld
FSRKLLLIRNN-KNNMLRRLAHFQVDGWSNDDITScneGAIINTMNLVKTlqrkspNSPILMHCSNMIGRSAVFCAAMATVDQMKSSSVVD--------V
. ||... .... |.. |.. .| . . . |... ..|. . . |.|.||| ..|.....|. . .. . .|| .
yilrellltlllsagearevmhlhytdwpdhgvpq...eallellellld......ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlyl
FQTVKNMRVNLPGAVQNKGQYKMIHTLAAAYVNL
...|. .| |||||. .||.... ......
eeaveelraqrpgavqteeqylflyeallellrs
|
|||||||||
subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 254-511 | 8.1e-32 | 105.4 | In-house | 16-276 (307) | alignment | ||
Range on Protein: 254-511
Range on HMM: 16-276/307.0
TGFEAQFNVLEQVSvpPQDAVCDVARQHPRKNRYQEILPTDQWRVHLKSE--SPDYINAVFIPSYKNDKGFIIAQSPLRETRRDFWKMIFDREITTIVML
. . .|.|| . . |. . . . |||||.. |. |. .| . . ||| | .. . | || || || .|. .|| |. . .. ...||
qalvdefrvlakkt..pegvtveafsantdknryqdvkcqdkgrivvkfdglasdyihanylgiaikpkkficaqgplentqysfwamaiqekvesviml
SPIMEGEEEACAQYWPKEG--TIEFGE--FTISVREeWGHQSFSRK--LLLIRN---NKNNMLRRLAHFQVDGWSNDDITSCNEGAIintmNLVKTLQRK
..| . | |||| | . ||| |||| . | . .. |. . . . . | . |.| . | . . | .|| ||... . .
ckvielakikceqywpleegqklvfgeapntisvan.lgakklapdedlinvttlkvdwaqksrtiqhlqwenwpdrgvpqinltai....nlleavryd
spNSPILMHCSNMIGRSAVFCAAMATVDQM-KSSSVVDVFQTVKNMRVNLPGAVQNKGQYKMIHTLAAAY
. |...||| .||| | |.| . |. . |...| . . |.|.. || .| . |
..tnpvvvhcsaGvGrsGtivaislvqdkmiaGinckdmkklveelrsqrhyaiqteaqylylhrvlley
|
|||||||||
subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 9-225 | 1.4e-31 | 104.6 | In-house | 81-276 (307) | alignment | ||
Range on Protein: 9-225
Range on HMM: 81-276/307.0
SQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSRGSEDygpfTVTLQKettSNSFIIReltlhyntmmgNLRSKIVNPTGRID
.|.|..||||. |. .|| |. ||| ...|| |. | .||| |||| . | .. .|. . || .| . | .
pkkficaqgplentqysfwamaiqekvesvimlckvielakikceqywpleegqk....lvfgea...pntisva...........nlgakklapdedli
PNKKEYYSSAQSTLLITHYQFIDWLEYGpQPPINsLVKFNKIisNQTEHKKGPIVVHCSTGGGRTGAFIGMSCsIKDALT--ESIIDIPAVVTIMREQRM
. || . |.|.|. .| . | |.|| | | . . .. .. |.|||||.| ||.|. ...| ..| . . |. .| .|.||
nvttlkvdwaqksrtiqhlqwenwpdrg.vpqin.ltainll..eavrydtnpvvvhcsaGvGrsGtivaisl.vqdkmiaGinckdmkklveelrsqrh
MMIQTLDQYMLVHEAVLEQ
||| ||. .| .||
yaiqteaqylylhrvlley
|
|||||||||
0041856 | (Phosphotyrosine protein) phosphatases II | 283-510 | 1.4e-31 | 104.9 | In-house | 3-169 (182) | alignment | ||
Range on Protein: 283-510
Range on HMM: 3-169/182.0
RKNRYQEILPTDQWRvhlkseSPDYINAVFIPSYKNDKGFIIAQSPLRETRRDFWKMIFDREITTIVMLSpimegeeeaCAQYWPkegtiefgeftisvr
||||..||| |. | .||||| .. .. .. ||..| || .| ||..|. .. |||||.|. . .|||
dknrysdilpydhsr......dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt.........eelywp...............
eewghqsfsrklllirnnkNNMLRRLAHFQVDGWSNDDITScnEGAIINTMNLVKTlqrksPNSPILMHCSNMIGRSAVFCAAMATVDQmkSSSVVDVFQ
.. | ... .| ..... ... .. |. .. |.| ||| .||.....|| . . |. ....
...................ellerlgiqylylpwpDhgvpd..ldelldfieevle.....eggpvlVHCsaGvgRtgtlvaaylmkkl..gvsleeavk
TVKNMRvnlPGAVQNKGQYKMIHTLAAA
.|...| ||.|.. || ... ..
lvrsrR...pgmvitpnqyfflqlalle
|
|||||||||
subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 119-244 | 4.9e-31 | 103.0 | In-house | 175-301 (305) | alignment | ||
Range on Protein: 119-244
Range on HMM: 175-301/305.0
QSTLLITHYQFIDWLEYGPQPPINSLVKFNKIISNQTEHKKG-PIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMREQRMMMIQTLDQYML
. . ...||. || . | ||... | . .. .. || |..|||| | ||||.|| .. . . .| ..|. |. .|..|| |.||||||.
kesrtvlqyqltdWPdhGvpqfatsllslikrvqkdqkkdkgvpllVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkmvqtldqYvf
VHEAVLEQALCGDTQIVACDLQNTISS
.|.|. | ||||.|. .|. .
lhdaldelitcgdtsiigsnlrarvnk
|
|||||||||
subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 256-506 | 5.4e-31 | 102.5 | In-house | 22-273 (439) | alignment | ||
Range on Protein: 256-506
Range on HMM: 22-273/439.0
FEAQFNVLEQVSVPPQDAVCDVARQH-PRKNRYQEILPTDQWRVHLK----SESPDYINAVFIPSYKNDKGFIIAQSPLRETRRDFWKMIFDREITTIVM
|. |. .. .| . . . .|... ||||... . | || |. |||| .| | .|| .| .| | .|| |||...... .||||
fkeifekinstspdyaciaslaaqeydqtknrykdvgafdhtrvtlqeipgvphshyinanyikGyyddklyiatqgpkkettddfwrlviekktvtivm
LSPIMEGEEeacaqYWPKEGTIEFGEFTISVREEWGHQSFSRKLLLIRNN--KNNMLRRLAHFQVDGWSNDDITScNEGAIINTMNLVKTLQRKSPNSPI
|. ..| ||| .. . .|. .. | . . . . . |. ... | . .|. | . .. . . ... . ... . | |.
ltnlvesyk.....ywpsdaevcygdiavrvdrnielpnyvirgfkvfnerdttekertvlqfhyiawpdknvpa.qashvldflrainsandkeeygpv
LMHCSNMIGRSAVFCAAMATVDQMKSSSVVDVFQTVKNMRVNLPGAVQNKGQYKMIHT
..||| .||. | ...|.|. ||. || .| . ||. || .|.
vvhcsagvGrtGtiialdialeqlklenkvdikgivkvlrkqrkqmvqalcqyvfiyn
|
|||||||||
subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 8-89 | 1e-30 | 101.9 | In-house | 87-168 (318) | alignment | ||
Range on Protein: 8-89
Range on HMM: 87-168/318.0
QSQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSRGSEDYGPFTVTLQKETTSNSFIIRELTLHY
....|||.|.|| .|. |||||||. ... |||||...| ..|. .||||.||. || .|.|..|........||....
rkkayiaaqaPlpetieDfWrmvWeqnsavivmltqeeergkakvhryWPskgsrsygklvvelkeevelsdyvlrefkvtr
|
|||||||||
subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 123-260 | 2e-30 | 100.9 | In-house | 176-315 (318) | alignment | ||
Range on Protein: 123-260
Range on HMM: 176-315/318.0
LITHYQFIDWLEYGPQPPINSLVKFNKIIS-NQTEHKKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMREQRMMMIQTLDQYMLVHEA
. |.. .| . | ||... . .| |.....||||||||.| |||| || .. .. . |...|. .|. .|||| .|.|| ||| .....
qvrqyhytsWpdegvpesgaslldlvrqvskaqqksgagpivvhCsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqtedqyefiydv
VLEQALCGDTQIVACDLQNTISSLSSSDNA-SVTGFEAQF
.|| .|||.. | ||.. | | .|. | ..|.|
llealasgdtevdasdlrsrirelreqdpesgttemdaef
|
|||||||||
subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 7-92 | 7.9e-30 | 98.7 | In-house | 88-173 (290) | alignment | ||
Range on Protein: 7-92
Range on HMM: 88-173/290.0
EQSQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSRGSEDYGPFTVTLQKETTSNSFIIRELTLHYNTM
.....|||||||. .|.||||...|||| ..|||||. .|. . || ||||......||.|...|..|.| |..|.|.| .. ..
kekkqyiatqgpvsntlvdFWkliwqekvtiivmltniieegkvkCqqYWpdsdtkaygefsikllneetlneyierklevknkns
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 282-510 | 1.5e-29 | 97.8 | In-house | 33-293 (297) | alignment | ||
Range on Protein: 282-510
Range on HMM: 33-293/297.0
P-RKNRYQEILPTDQWRVHLKSESP--DYINAVFI--PSYKNDKGFIIAQSPLRETRRDFWKMIFDREITTIVMLSPIMEGEEEACAQYWPK--EGTIEF
|||||..|| ||. ||.|. . ||||| .. | ..| .|.|| ||..| |||........ .|||.. . |. . || |||. .. .
slrknryrdilatddtrvkllrviterdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrdkcapywpsvvqerlka
GEFTI----SVREEWGHQSFsRKLLLIRNnknNMLRRLAHFQVDGWSNDDITS--------------CN-----EGAIIN-----TMNLVKTLQRKSP-N
|.. . |. .|. . . .| || . | . | | .| . . | | |... . ...|. . | |
gdvvveflsstsdefdrvil.telqliyr...sesrvvrhvqflswpdhGvpsdledlvrfqaqvcscciavpmmlalvemftamvflqleslraemprn
SPILMHCSNMIGRSAVFCAAMATVDQMKSSSVVDVFQTVKNMRVNLPGAVQNKGQYKMIHTLAAA
..|.||| .||| | ... ..... . || .. .| . . || |........ .
ayllvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqtleqfellydavlk
|
|||||||||
subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 248-506 | 1.7e-29 | 97.4 | In-house | 5-263 (281) | alignment | ||
Range on Protein: 248-506
Range on HMM: 5-263/281.0
SDNASVTGFEAQFNVLEqvSVPPQDaVCDVARQ--HPRKNRYQEILPTDQWRVHLKS-----ESPDYINAVFIPSYKNDKGFIIAQSPLRETRRDFWKMI
|.. .. |. .| | || | .| | | .|||| .| | ||.|| .| ||| | .| | .|.|..| | .||| |||.||
sqkmtlddfkqefsnlp..gdppsd.lctvfnqpvnnkknrylnipcldisrvqlkvkmpnknstdyihanyirspflkrgyiltqgpkketradfwrmi
FDREITTIVMLSPIMEGEEEACAQYWPKEG--TIEFGEFTISVREEWGHQSFSRKLLLIRnnKNNMLRRLAHFQVDGWSNDDITSCNEgaiInTMNLVKT
.. . |.|||| ..| . | ||.|.|.. ..| ....| . .|. | . . | ..|. | . .. | . .....
wqenttaivmlcqfletnrekcaeyfprnahcclqfdklsvsyedstvnkslvttrlnls..yegetrlithwlwkewpdwqvpesse...v.mlkilrk
LQRKSpnSPILMHCSNMIGRSAVFCAAMATVDQMKSS-SVVDVFQTVKNMRVNLP-GAVQNKGQYKMIHT
.. .| .| ..||| .||| . | ... ..| .. |. | | .|| .|| || .|
irars..tppvihcsagvgrsgtlmaveialqsihshftlpdikqivshlrvtgraasvqtlqqymliwk
|
|||||||||
subfamily_PTPRA_pd | Subfamily PTPRA | 8-88 | 3.5e-29 | 96.7 | In-house | 99-179 (330) | alignment | ||
Range on Protein: 8-88
Range on HMM: 99-179/330.0
QSQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSRGSEDYGPFTVTLQKETTSNSFIIRELTLH
. .|.||.|||...|| |||||.|. |...|||||.|.| . || ||||. |. || .|....|| .... .|.. ..
ekdkfiaaqGPkeetvedfwrmiweqksativmltelkerkeekcaqywPdeGlvtyGnirvevedetvlvdytvrkflvq
|
|||||||||
subfamily_PTPRB_pd | Subfamily PTPRB | 6-95 | 5.8e-29 | 96.0 | In-house | 90-180 (293) | alignment | ||
Range on Protein: 6-95
Range on HMM: 90-180/293.0
DEQSQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSR-GSEDYGPFTVTLQKETTSNSFIIRELTLHYNTMMGN
.. ...||||||| || |||||||..|. .|||||.| | ..|| .|||. . || .|||..|.. . ..||||... .... .
ynsprefiatqGPlpetvddfWrmvwekkssiivmltqlvekgkvkCeeYWPadeepvlyGdikvtlvaeeeledwvirelkiekekeerk
|
|||||||||
subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 9-224 | 6.6e-29 | 95.6 | In-house | 87-285 (305) | alignment | ||
Range on Protein: 9-224
Range on HMM: 87-285/305.0
SQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSRGsEDYGPFTVTLQKETtsnsfIIRELTLHYnTMMGNLRSKIVNPTGRID
....| || ||..| ||| | .|.| || || .|.| ||..|..|. .| | || . . | . . . . ..|. . |.
pkrfictqaplektcadfwymclqdkveaifmlcnllekgakkcleyfaskd.kdvlefeekgqkis.....vkfessvtl.kfrkdakakvtetvlvie
pnkkeyySSAQSTLLITHYQFIDWLEYGPQPPINSLVKfnkiISNQTEHKKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIID-IPAVVTIMREQRMM
. .... .||| .||| . | . ..... . ... |||||||||.| ||||. . . ... |. ||. .. .||||
.......gpgekarkvthyhwidwpdrgvpaadlaile....llekarpskgpivvhcsagigrtgsvvmleyildqllagqiiedtdkilqkireqrnn
MIQTLDQYMLVHEAVLE
||| .||..||. .|.
siqtdaqylfvhqviln
|
|||||||||
subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 281-503 | 9.5e-29 | 95.1 | In-house | 50-272 (301) | alignment | ||
Range on Protein: 281-503
Range on HMM: 50-272/301.0
HPRKNRYQEILPTDQWRVHLKSESP-DYINAVFIPSYKNDKGFIIAQSPLRETRRDFWKMIFDREITTIVMLSPIMEGEEEACAQYWPKE--GTIEFGEF
. |.||... . |.. .. | | .||. . . ||..|.||..|. ||| |. .. .||||. .| .|| |..| | . ... | |
pkdkhryptvPckPstavevivdGkrvPihanwiptsGhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkisekldigrf
TISVREE---WGHQSFSRKLLLIRNNKNNMLRRLAHFQVDGWSNDDITSCNeGAIINTMNLVKtlqrKSpNSPILMHCSNMIGRSAVFCAAMATVDQMKS
.| .... .. |.| . .. | . |.| |.. .. . . |.||| || . ||..|||. |||| | .. ....
kikiknkelilnkkiskrtlevedstgkfatrtvthyqysewtdrgvPksh.aelfdlmelvk....ks.ekPivvhcsaGiGrsvafigteylarevea
SSVVDVFQTVKNMRVNLPGAVQNKGQYKM
... ...|..| . .||.. |
dptieltealkhlrehrwngvqtnsqlyw
|
|||||||||
subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 8-216 | 1e-28 | 95.0 | In-house | 88-271 (301) | alignment | ||
Range on Protein: 8-216
Range on HMM: 88-271/301.0
QSQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSRGSedygpftvtlqkettsNSFIIRELTLHYNTMMGNLRSKIVNPTGRI
.....|||||||. | ||| |. | . ||||.. |.| ||..| |.. | ... | ... ... |. ||.. | ..
hphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkis................ekldigrfkikiknkelilnkkiskrtlev
DPNKKEYyssaqSTLLITHYQFIDWLEYGPqpPiNSLVKFNKIIsNQTEHKKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMREQRMM
... .| .||||. .| ..| | .| .. ... . . . |||||||.| ||. |||| . .. ... |.. . .||.|
edstgkf.....atrtvthyqysewtdrgv..P.kshaelfdlm.elvkksekPivvhcsaGiGrsvafigteylareveadptieltealkhlrehrwn
MIQTLDQYM
.|| |
gvqtnsqly
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 5-223 | 1.2e-28 | 94.9 | In-house | 99-341 (350) | alignment | ||
Range on Protein: 5-223
Range on HMM: 99-341/350.0
DDEQSQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSRGSEDygpFTVTLQKeTTSNSFIIRELTLHYNTMMGNLRskiVNPT
. . . ||||||.|| .|| ||.... . | |..||...| . || .||. . .| .|| |. . | |.. .|. . .. |
einpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcyrYWqegsydd...itvklas.kwenimgindsslysadvkkeas...dndn
GRIDPNKKEYYSS------AQSTLLITHYQFIDWLEY----GPQPPINSLVKFNKIISNQT------EHKKGPIVVHCSTGGGRTGAFIGMSCSIK----
| . |...| | . . . |. |.. |. ...| |..| . . . . ||.|||| | |||| .. . ..
isddndlkdnnsltaitlaasdPyvvyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfei
-DALTESI----------IDIPAVVTIMREQRMMMIQTLDQYMLVHEAVL
. ||. | .| ..|.||. |.|.|||.. ..||.|
lenltkesrkldvaaktrDlisiivnelrkqrismvqnldqfifiYeall
|
|||||||||
subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 279-509 | 1.5e-28 | 94.6 | In-house | 33-267 (285) | alignment | ||
Range on Protein: 279-509
Range on HMM: 33-267/285.0
RQHPRKNRYQEILPTDQWRVHLKSESPDYINAVFIPSY-KNDKGFIIAQSPLRETRRDFWKMIFDREITTIVMLSPIMEGEEEACAQYWPKE--GTIEFG
| ||| .. .. || || ||| | .. |.. .| .| || || |||.||.. .|. ..|| ..|| | || |.|.. ..||
eanpdlnryadvrcieetrvvlknhdrdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyypeklgevvkfg
EFTISVRE---EWGHQSFSRKLLLIrNNKNN--MLRRLAHFQVDGWsNDDITSCNEGAIINTMNLVKTLQRKspNSPILMHCSNMIGRSAVFCA-AMATV
.. |.. | | . | .| | .. . | || | |... . .|. . || .. | . || .||| .||.| | ||.
kyeitlteckeeaiagtilnaltvi.ntedasseplymnhvqvpww.pdqlapedarpmielykwvkkvnpk..ekpicvhcsagvgrtatfvgidyati
DQMKSSsVVDVFQTVKNMRVNLPGAVQNKGQYKMIHTLAA
|. ..... |..|| |||.. |. ... .
rimenp.niemldivremramrfqavqshmqflflyvvlm
|
|||||||||
0051082 | (Phosphotyrosine protein) phosphatases II | 12-223 | 2.8e-28 | 93.8 | In-house | 15-150 (151) | alignment | ||
Range on Protein: 12-223
Range on HMM: 15-150/151.0
YIATQGPLDrtvvDFWRMVWQEKACAIVMLTKLQEDLriKCSQYWPSRGsedygpftvtlqkettsnsfiireltlhyntmmgnlrskivnptgridpnk
.....|||. ||........ .||.|....| .| .|.|. |
lyrsggpla....dflellkelgiktivnlrseeerg..ycpeylpelg...................................................
keyyssaqstLLITHYQFIDWLEYGPQPPINSLVKFNKIISNqteHKKGPIVVHCSTGGGRTGAFIGMSCSIKDaltesiIDIPAVVTIMREQRMMMIQT
. ..|....|| ..| . ......| ... . .|.||..|||| | ||||..... . . . ... ... .|..|....|.
..........ievlhipildwpdpglplsfdavleflellld...kkngpvlvHCsaGkgRTGtlvalylmllg......vsleealeeyrlkrpgvvqp
LDQYMLVHEAVL
.|..... |.|
nqqflfqlfall
|
|||||||||
subfamily_PTPRB_pd | Subfamily PTPRB | 118-224 | 4.1e-28 | 93.3 | In-house | 175-283 (293) | alignment | ||
Range on Protein: 118-224
Range on HMM: 175-283/293.0
AQSTLLITHYQFIDWLEYGPQPPINSLVKFNKIISNQT--EHKKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMREQRMMMIQTLDQY
.... ...|.|. | ..| ..|..| . . ... ...|.||||||| | ||||.|| . ... .| ..|| ..|. .||.|....|| .||
ekeerkvrqyhftsWpdhgvPektktlldfvrtvreaiektaskrPivvhCsaGvGRtGtfialdrllqaieeedyvdifgivaelReeRnllvqtekqY
MLVHEAVLE
. .|..||.
ifihqcvld
|
|||||||||
subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 8-92 | 5.2e-28 | 93.0 | In-house | 89-171 (319) | alignment | ||
Range on Protein: 8-92
Range on HMM: 89-171/319.0
QSQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSRGSEDYGPFTVTLQKETTSNSFIIRELTLhyNTM
. .|.||||.||. |. |||||||.|.. .||||||.| |..|...|||. |.|| ..|||..| . .|||.|.| |.
erekfiatqaPlentiedfWrmvWeeessivvmltklveklkvklkkywpeenfeeyGrlivtleeeeeledyiirklkl..nkk
|
|||||||||
subfamily_PTPN3_pd | Subfamily PTPN3 | 7-91 | 5.6e-28 | 92.7 | In-house | 81-166 (280) | alignment | ||
Range on Protein: 7-91
Range on HMM: 81-166/280.0
EQSQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSRG-SEDYGPFTVTLQKETTSNSFIIRELTLHYNT
.....||||||||..|. |||.|||..|. ||||| | |. |.|| ||||. . . .|| |.|...|| ...|...|||.|. ..
glvnryiatqGPlaktatdfWqmvweqksslivmlttlverGrvkChqyWPetedeleygefsvkcekedetksyvlrelvlkdke
|
|||||||||
0043147 | (Phosphotyrosine protein) phosphatases II | 303-506 | 8e-28 | 92.7 | In-house | 3-155 (172) | alignment | ||
Range on Protein: 303-506
Range on HMM: 3-155/172.0
ESPDYINAVFIPSYKNDKGFIIAQSPLRETRRDFWKMIFDREITTIVMLSPImegeeeacaqywpkegtiefgeftisvreewghqsfsrkllliRNNKN
|. ||||| ... | . ||. | |||.| |||.|. .. ||.||.| . ...
egsdyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltel...........................................lydpe
NMLRRLAHFQVDGWSNDDITscNEGAIINTMNLVKTLQRKSPNSPILMHCSNMIGRSAVFCAAMATVdqmKSSSVVDVFQTVKNMRvnlPGAVQNKGQYK
. | ... .| . . . ..........|. .||. |.| ||| .||.....|| .. |. .....|...| ||||||..||.
llerlgiqylylpwpDhgvp..llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml...lglsleeavalvrekR...pgavqnpsqyr
MIHT
..
flyy
|
|||||||||
0049772 | (Phosphotyrosine protein) phosphatases II | 10-224 | 8.5e-28 | 93.4 | In-house | 84-278 (314) | alignment | ||
Range on Protein: 10-224
Range on HMM: 84-278/314.0
QKYIATQGPLDRTVVDF----------WRMV--WQEKACAIVM---------------------LTKLQEDLrikcsQYWPSRGSEDYGpftvtlqkett
.|.|||||||. ||||| |||| .. . ||| |..| . ... . |..
lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivmsrdevladelsrLdaAlgKtpllildgng.....neptaadlellk...........
snsfiireltlhyntmmgnlrskivnptgridpnkKEYYSSAQSTLLITHYQFIDWLEyGPQPPINSLVKFNKIISNQteHKKGPIVVHCSTGGGRTGAF
.|.|. . |. .| |.. | .|... . .| ..| . .|.||..|||. | |||| |
...................................eelydpelferlgikylripvpD.gsaplledfdeflefieea..dkggpvlvHCkaGkgRtgtf
IGMSCSIKDAlteSIiDIPAVVTIMREQRM-----MMIQTLDQYMLVHEAVLE
. . . .| . .. .. .|..|. .|..|.|| ..||.||
vvaaylmkll...gv.sleealedvrlkRpinpnpgfieqleqyefilealle
|
|||||||||
subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 7-89 | 8.9e-28 | 92.3 | In-house | 86-170 (305) | alignment | ||
Range on Protein: 7-89
Range on HMM: 86-170/305.0
EQSQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSRGSE--DYGPFTVTLQKETTSNSFIIRELTLHY
....|||..||||. ||.||||....|| |||||||.|. . || |||| . .| ..|.|.|.|. |.| . .|.|.|..
krkkkyivaqgPlkntvadfWrliveekvstivmltklveggkdkCrqYWpesktekkefgefsvelksektasdyieRklkisi
|
|||||||||
subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 282-506 | 2.4e-27 | 90.6 | In-house | 9-235 (239) | alignment | ||
Range on Protein: 282-506
Range on HMM: 9-235/239.0
PRKNRYQEILPTDQWRVHLKSES----PDYINAVFIPSYKN-DKGFIIAQSPLRETRRDFWKMIFDREITTIVMLSPIMEGEEEACAQYWPKeGTIEFGE
|||| .|. |. || |. | ||||| .. | | .| .| . . |||.|... ||||. ..|| .. | |||| | .. .
kaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpd.stskycn
FTISVREEWGHQSFSRKLLLIRNNKNNMLRRLAHFQVDGWSNDDITSCNEgAIINtMNLVKTLQRKSPNSPILMHCSNMIGRSAVFCAAMATVDQMKSSS
. ...|. . . ... . . | . .... | . . |.. . | . | ..||| .||. | | . | |
lrvtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyat.avlg.lrrkitkdslpgarpwvihcsagvgrtgaflvidamlrqakkqk
VVDVFQTVKNMRVNLPGAVQNKGQYKMIHT
||.|. || .| . | || || .||
tvdifnyvkairedrphmvqtseqyvfihl
|
|||||||||
subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 282-506 | 2.5e-27 | 90.6 | In-house | 8-234 (239) | alignment | ||
Range on Protein: 282-506
Range on HMM: 8-234/239.0
PRKNRYQEILPTDQWRVHLKSES----PDYINAVFIPSYKN-DKGFIIAQSPLRETRRDFWKMIFDREITTIVMLSPIMEGEEEACAQYWPKeGTIEFGE
|||| .|. |. || |. | ||||| .. | | .| .| . . |||.|... ||||. ..|| .. | |||| | .. .
kaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpd.stskycn
FTISVREEWGHQSFSRKLLLIRNNKNNMLRRLAHFQVDGWSNDDITSCNEgAIINtMNLVKTLQRKSPNSPILMHCSNMIGRSAVFCAAMATVDQMKSSS
. ...|. . . ... . . | . .... | . . |.. . | . | ..||| .||. | | . | |
lrvtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyat.avlg.lrrkitkdslpgarpwvihcsagvgrtgaflvidamlrqakkqk
VVDVFQTVKNMRVNLPGAVQNKGQYKMIHT
||.|. || .| . | || || .||
tvdifnyvkairedrphmvqtseqyvfihl
|
|||||||||
subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 116-232 | 7.3e-27 | 89.1 | In-house | 167-284 (287) | alignment | ||
Range on Protein: 116-232
Range on HMM: 167-284/287.0
SSAQSTLLITHYQFIDWLEYG-PQPPINSLVKFNKIISNQTEHKKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMREQRMMMIQTLDQ
..|.... .. ||. .| . | . | .|. ... . .| . ...|||||| . ||.. |. . .|. . || .||. |. .| |.. ..|| .|
nkagdkqqvkqyqitnWdstgkvtepqtillvieemyktqrkrgntsivvhCsdtvGrsamfcaaattinkckteGviDvfqvlksqriqkpgsvqtveq
YMLVHEAVLEQALCGDTQ
|. . ..|||. ...|.
ykfindivleyldsfety
|
|||||||||
subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 276-511 | 9.1e-27 | 88.8 | In-house | 38-270 (288) | alignment | ||
Range on Protein: 276-511
Range on HMM: 38-270/288.0
DVARQHPRKNRYQEILPTDQWRVHLKSESPDYINAVFIPSYKNDKGFIIAQSPLRETRRDFWKMIFDREITTIVMLSPIMEGEEEACAQYWPKE--GTIE
|. . | ..||... | ||.|. .. ||.| ..| |... .| ||.||. | .|||... .. ||||. ..| |. |.|.| . ..
dsfianptrdryenlprcditrvklsddpdfyiaanvvssakykrrlicaqaPlngtieelWkmllesdveyivmlcellekGkeksaeyfPsklGekar
FGEFTISVREEWGHQSFSRKLLLIRNNKNNMLRR-LAHFQVDGWSNDDITScnegAIINTMNLVKTLqrKSPNSPILMHCSNMIGRSAVFCAAMATVDQM
.| . |... |. |.|..|. . . . . | .| . . ..|.. | || . ||..|.|. .||.. . . ....
igrlctvvkkkradidklvkvsllriskegeekvivkilhlleWdddgvPe....nylsplrllevl..kslqkPivvhssaGvGrtgtlililialesl
KSSSVVDVFQTVKNMRVNLPGAVQNKGQYKMIHTLAAAY
... . . . ....| . |.| . || .| . .
rlddflgirsllaklreerfkaiqtemqylyvhrcvlee
|
|||||||||
0046846 | (Phosphotyrosine protein) phosphatases II | 297-510 | 1.3e-26 | 88.8 | In-house | 4-171 (176) | alignment | ||
Range on Protein: 297-510
Range on HMM: 4-171/176.0
RVHLKSESPDYINAVFIPSYKndkgFIIAQSPLRETRRDFWKMIFDREITTIVMLSPIMEGEEEACAQYWPKEGTIEFgeftisvreewghqsfsrklll
|.. ...||||| .| ... .|. | ||..| ||..|... ||..|.| .| . |..||| . . ..
rllgldldldyinanlilgsr....piatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgi......................
irnnknnmlrrlaHFQVDGWSNDDITSCneGAIINTMNLVKTLQRKSpnSPILMHCSNMIGRSAVFCAAMatvdQMKSSSVVDVFQTVKNMRVNLP-GAV
.... .| .. . .... ...... ... |.| ||| |||.....|| .... ..|..... .| | |||
.............qylhlpwpDhgvpdl..elllellefirealkeg..gpvlVHCsaGigRtgtlvaay....llelekglsveealalvreqRplgav
QNKGQYKMIHTLAAA
|. .||.... .
qtpeQyrflyefell
|
|||||||||
0044763 | (Phosphotyrosine protein) phosphatases II | 11-222 | 1.9e-26 | 88.2 | In-house | 30-167 (178) | alignment | ||
Range on Protein: 11-222
Range on HMM: 30-167/178.0
KYIATQGPldrtvVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSRGSedygpftvtlqkettsnsfiireltlhyntmmgnlrskivnptgridpn
|.....| .|......... .||.||. .| ..|| .|||.. .
lylgslpp.....addlellkelgithivnlteelelgflkcdpywpeeag.................................................
kkeyyssaqstlliTHYQFIDWLEYGPQPPINSLVKFNKIISNQTEHKKGPIVVHCSTGGGRTGAFIGMSCSIKDaltesIIDIPAVVTIMREQRMmMIQ
.|..| . .|... . . .| ..| . . |.||..|||| | ||.|... . .| ....... .||.|. ...
..............iqylhipipDhgvpdllehflefvefieealdekggpvlVHCsaGvgRsgtlvaaylmkkl.....glsleeaielvrerRp.ivp
TLDQYMLVHEAV
. .|. ..|
npgqlrqLyefe
|
|||||||||
subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 123-268 | 2.5e-26 | 86.9 | In-house | 173-319 (515) | alignment | ||
Range on Protein: 123-268
Range on HMM: 173-319/515.0
LITHYQFIDWLEYGPQPPINSLVKFNKIISNQTEHKKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMREQRMMMIQTLDQYMLVHEAV
.| ..| .| . | .. .||.|. | . .... . |...|||.| |||| .| . . .| | ..|. .||..|..|. ..|| .|| ....||
tvtqfhfteWPdkGvpkhtssllklikevkadhgqythpliihcsaGvGrtGvvisidsvvahakttrmvdvfnfvtnirqkrpylvqtqeqyafiygav
LEQALCGDTQIVACDLQNTISSLSSS-DNASVTGFEAQFNVLEQVSV
||. | .| | . . . | || | . . .|. |. .
ledllwrntlipvihftdhlqdlhssgdgrgrskmtkefqtlkslcp
|
|||||||||
subfamily_PTPRA_pd | Subfamily PTPRA | 120-247 | 6.5e-26 | 86.0 | In-house | 189-316 (330) | alignment | ||
Range on Protein: 120-247
Range on HMM: 189-316/330.0
STLLITHYQFIDWLEYG-PQPPInSLVKFNKIISNQTEHKKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMREQRMMMIQTLDQYMLV
.. |.. . | | . | | || ..|. | . .. . . ||||||||.| ||||.|| .. .. .| ..|. .| .| || |.||. || ..
ksrlvrqfhftswPdvGvPfepi.GmlkllkkvkklnqqsagpivvhcsaGvGrtGtfivldavlervkaerkvdvfefvkrlrlqrpqmvqtdeqyefi
HEAVLEQALCGDTQIVACDLQNTISSLSS
....|| | |||.. . |.. . .| .
ykvlleyylygdteldvsslekhlqklyn
|
|||||||||
subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 8-92 | 2.2e-25 | 84.2 | In-house | 84-168 (287) | alignment | ||
Range on Protein: 8-92
Range on HMM: 84-168/287.0
QSQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSRGSEDYGPFTVTLQKETTSNSFIIRELTLHYNTM
.....|....|. .|...||....... |||||....|. . .| ||||. | .|.....| .|......|.|.| .. ..
ekkafiiaesPmfntarnfWkliddrnvtaivmlcqekendeevcyqyWpeeksvvlGeyniellneevnagyierklevknknk
|
|||||||||
subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 7-92 | 2.3e-25 | 84.3 | In-house | 50-133 (250) | alignment | ||
Range on Protein: 7-92
Range on HMM: 50-133/250.0
EQsQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIkCSQYWPSRGSEDYGPFTVTLQKETTSNSFIIRELTLHYNTM
|. . .||||||| .|..||||||..||. .|||||.|.| . ..|||| ..| || ||.| .. . ...|.| | ..
er.kafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqywPvekaekyGdvtvsllskeefadytkrklklskakk
|
|||||||||
subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 116-225 | 5.7e-25 | 82.8 | In-house | 172-282 (290) | alignment | ||
Range on Protein: 116-225
Range on HMM: 172-282/290.0
SSAQSTLLITHYQFIDWLEYG-PQPPINSLVKFNKIISNQTEHKKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMREQRMMMIQTLDQ
.||... .|.||. | . | . | .|. ..... .| . ...|||||| . ||.. |. . .|. . || ||. .|. .| |.. ..|| .|
nsagakqsvtqyqitnwdstgkvtnpqtillvieemyktqrkrgntsivvHCSdtvgrsavfcaaattinkcktegvidvfqvlksqRiqkpgsvqtvqq
YMLVHEAVLEQ
| .... ||.
yqgifqivlty
|
|||||||||
0049260 | (Phosphotyrosine protein) phosphatases II | 312-505 | 1.4e-24 | 81.9 | In-house | 1-143 (152) | alignment | ||
Range on Protein: 312-505
Range on HMM: 1-143/152.0
FIPSYKNDKGFIIAQSPLRETRRDFWKMIFDREITTIVMLSPIMEGEEEACAQYWpkegtiefgeftisvreewghqsfsrklllirnnknnmlrrlahf
||. |.. . ||..| |...| |||.|. . ||||||| .| .. |.||.
fidgyampfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi.............................................
QVDGWSNDDITSCNEGAIINTMNLVKTLQRKSPNSPILMHCSNMIGRSAVFCAAMATVdqmKSSSVVDVFQTVKNMRvnlPGAVQNKGQYKMIH
|. . .| . .. .. ..|. ..... |.| ||| .||.....|| . |. .... |...| ||||.|.||.. ..
qylhlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml...lgvsleeavalvrekR...pgavpnpgqlrfly
|
|||||||||
subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 120-248 | 1.6e-24 | 81.6 | In-house | 176-310 (325) | alignment | ||
Range on Protein: 120-248
Range on HMM: 176-310/325.0
STLLITHYQFIDWLEYGPQPPINSLVKFNKIISNQTEH------KKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMREQRMMMIQTLD
|. . .|. | . | | .|. . ... . | .||.||||.| ||||.|| . . .. ..|| .|| .| .|..| |..| |
etrsvkqfqlqswddmGvqkrpatlisilqlvkavservtantkastpilvhcsaGvGrtGvfislysalakvieesrvdifgfvkklrkdrpsmvetvd
QYMLVHEAVLEQALCGDTQIVACDLQNTISSLSSS
||.|..||. | ..|.|.. . .. .|||
qyiliyealveaymsgntdvpvssfeaklsslqer
|
|||||||||
subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 9-98 | 2.5e-24 | 81.2 | In-house | 103-186 (319) | alignment | ||
Range on Protein: 9-98
Range on HMM: 103-186/319.0
SQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTklqedlRIKCSQYWPSRGSEDYGPFTVTLQKETTSNSFIIRELTLHYNTMMGNLRS
.||||.||||| |. |||||.|. ....||.|| . ||||||| .. . .. | | .. . .. ...|.. | .. . . |.
kdkyiaaqGPldntladfWrmiweyncstivllt......kdkcsqywplkivikeerfkvkvdsveetaeyvvrdielsedgkekdirk
|
|||||||||
subfamily_PTPN9_pd | Subfamily PTPN9 | 8-90 | 3.2e-24 | 80.5 | In-house | 83-167 (297) | alignment | ||
Range on Protein: 8-90
Range on HMM: 83-167/297.0
QSQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWP--SRGSEDYGPFTVTLQKETTSNSFIIRELTLHYN
| . .|||||||..|| |||||||.... ||| |.. | |.||.|||| . |...| ..|. . ... . .| |...
qkkafiatqGplkktvsdfWrmvWeqevlvivmttrvvergrlkcgqyWpleeessaefgdlsvsnveveeeedykvrvleiknv
|
|||||||||
subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 8-98 | 3.9e-24 | 80.6 | In-house | 66-150 (284) | alignment | ||
Range on Protein: 8-98
Range on HMM: 66-150/284.0
QSQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTklqedlRIKCSQYWPSRGSEDYGPFTVTLQKETTSNSFIIRELTLHYNTMMGNLRS
. .|||||||||| |. |||||.|. ....||.|| . ||||||| .. . .. | | .. . |. ...|.. | .. . . |.
rkdkyiatqGPldntladfWrmiweyncstivllt......kdkcsqywplkivikeerfkvkvdsveeseeyvvrdielsedgkekdirk
|
|||||||||
subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 260-387 | 6.1e-24 | 79.1 | In-house | 26-167 (392) | alignment | ||
Range on Protein: 260-387
Range on HMM: 26-167/392.0
FNVLEQVSVPPQDAVCdvARQHPRKNRYQEILPTDQWRVHL----KSESPDYINAVFIPSYKNDKGFIIAQSPLRETRRDFWKMIFDREITTIVMLSPIM
| | . . || . .||||..||| |. ||.| . ||.|| .|||..|.| .| .|.| . |||.|.|. ..|||.|.. .
fhdlpgpdiypqtvaq..keinlkknryknilpydsarvkleviddipdsdylnasyipsfdnekayiasqgpnaaslddfwrmvfqenvttiamvtklk
EGE----EEACAQY----WPKEG----TIEFGEFTISVREEWGH
||. ..||. || .. | . .| |. ..|.
egdkgddartvaqfhftewPdkdvpkhtssllkfikevkadfGq
|
|||||||||
subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 126-260 | 8.3e-24 | 79.1 | In-house | 179-314 (315) | alignment | ||
Range on Protein: 126-260
Range on HMM: 179-314/315.0
HYQFIDWLEYGPQPPINSLVKFNKIISNQTEHKKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMREQRMMMIQTLDQYMLVHEAVLEQ
... | . | .|... . . . . |.|||||| | ||||.|| ... .. | .| .||. ..| .|..|. |.|...|| ....|.||
qlhytswpdmgvpkytiplmnlirtvkqhhtnsvgaivvhcsaGvGrtGtfitldavldqaeaenaidvynfitgvrqnrikmvqvaeqyqfiydallet
ALCGDTQIVA-CDLQNTISSLSSSDNASVTGFEAQF
.|||| | ||. | |. | .. | .. ||
fvcgdtsiaqdlylqrydsllapspdtgstllqeqf
|
|||||||||
subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 253-512 | 9e-24 | 78.4 | In-house | 25-285 (302) | alignment | ||
Range on Protein: 253-512
Range on HMM: 25-285/302.0
VTGFEAQFNVLEQVSVPPQDavCDVARQHPRKNRYQEILPTDQWRVHLKSESPDYINA--VFIPSYKndKGFIIAQSPLRETR---RDFWKMIFDREITT
. ...|. .... |. . | . .....||. ... |. .| |. | .|.|| | .|. . . |.|| | ... .||.|.|...|..
taevkkefkkidtmkvdlek..CkafkknlkknqsedvpildsnlvkleaepdsyvnaskvevPelt..rsiilaQlpkvdsedsveeFWrmvfqekivs
IVMLspIMEGEE-EACAQYWP--KEGTIEFGEFTISVRE--EWGHQSFSRKL-LLIRNNKNNMLRRLAHFqvDGWSNDDITsCNEGAIINTMNLVkTLQR
.|.| ..| | .. ...| . |.|.. . .| . . . . .| . | .| . .. . | .. . . ...|.|. | .
vvil..vgeeelkktlselfpkksgdykeygkmfvNnrkVekaeeektryviEvlPegcsnsvlanvyvl..tnWkqkkvp.vkyaeliktaakv.fakk
KSPNSPILMHCSNMIGRSAVFCAAMATVDQMKSSSVVDVFQTVKNMRVNLPGAVQNKGQYKMIHTLAAAYV
. ...... | .|| ..| .....|....... . . ..||..| . | ||.. || ... .. |.
ikadentvivSknGaGRagafltlavaveklqkgkepnikeivksiRsqRpravdslkQyvslyialllyi
|
|||||||||
subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 120-224 | 1.1e-23 | 78.7 | In-house | 168-274 (281) | alignment | ||
Range on Protein: 120-224
Range on HMM: 168-274/281.0
STLLITHYQFIDWLEYGPQPPINSLVKFNKIIS-NQTEHKKGPIVVHCSTGGGRTGAFIGMSCSIKDALTE-SIIDIPAVVTIMREQRMMMIQTLDQYML
| ... ... | . | . |..| | . .....| |.|.|||.| ||||..|.. .| . .| . .|. |||. .|..|..|.||. ||
etreveqlaytaWPdhGvPattkellefrkevlkltekktkaplvihCsaGvGrtGtyialDrlvkaveaeleeldvkavvaelrkernlmvqtvvqyef
VHEAVLE
|. |||.
vykavld
|
|||||||||
PTPc_DSPc_SM00012 | 124-224 | 1.1e-23 | 78.8 | In-house | 2-105 (105) | alignment | |||
Range on Protein: 124-224
Range on HMM: 2-105/105.0
ITHYQFIDWLEYG-PQPPiNSLVKFNKIISNQTEHKK--GPIVVHCSTGGGRTGAFIGMSCSIKDALTE-SIIDIPAVVTIMREQRMMMIQTLDQYMLVH
..||.. .| . | |... .|.... . . ....... .|.|||||.| |||| |. ... ... .| . .|| .| .|.||. |.||..||. ..
vkhyhytgwpdhgvPees.dsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylfly
EAVLE
.|.||
ralle
|
|||||||||
subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 7-89 | 1.6e-23 | 78.2 | In-house | 81-164 (281) | alignment | ||
Range on Protein: 7-89
Range on HMM: 81-164/281.0
EQSQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSRG-SEDYGPFTVTLQKETTSNSFIIRELTLHY
.. ..|||||||. ..|.||.|||..|..||||.|. | ..|| .||| . || .||. ..|......| |...|.
kgekeyiatqgPvPaslvafWqmvweqkvsaivmvtreieagklkChrYWPddnselkygdvtvkstaeeekatyierkfkler
|
|||||||||
subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 118-228 | 2.1e-23 | 77.8 | In-house | 133-244 (250) | alignment | ||
Range on Protein: 118-228
Range on HMM: 133-244/250.0
AQSTLLITHYQFIDWLEYGPQPPINSLVKFN-KIISNQTEHKKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMREQRMMMIQTLDQYM
.. .. ...|. | . | .. ... |. ..| . ...|..|.||.| ||.|||| ... .. . .| ..|. |. ..|..|. ....|.||.
kaderivrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidavlerlkkekvvdvfkvikvlrkdrphavesleqyv
LVHEAVLEQALC
|.|..|. .
fvyeiilkalds
|
|||||||||
subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 118-235 | 2.5e-23 | 77.6 | In-house | 173-293 (297) | alignment | ||
Range on Protein: 118-235
Range on HMM: 173-293/297.0
AQSTLLITHYQFIDWLEYGPQP--PINSLVKFNKIISNQTEHKK-GPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMREQRMMMIQTLDQ
|... .. |||..| . . ..||.|. . . .. .... ||..|||..| |||| .. . . .| | .|| .|. .|..|. ..|| .|
akarrvvkqyqfveWPdkaverkdsassllklisevrkdfsqnaegPllvhclaGvGrtgvlltidsvvaeakrekevdifglvkklrqerpylvqtkeq
YMLVHEAVLEQALCGDTQIVA
| .|..|||| |. ||.| |
ykfvyvavleallsedtriqa
|
|||||||||
subfamily_ptpA1_pd | Subfamily ptpA1 | 257-471 | 2.6e-23 | 77.5 | In-house | 24-255 (418) | alignment | ||
Range on Protein: 257-471
Range on HMM: 24-255/418.0
EAQFNVLEQvSVPPQDAVCDVARQHPRKNRYQEILPTDQWRVHLKS----ESPDYINAVFIPSYkNDKGFIIAQSPLRETRRDFWKMIFDREITTIVMLS
. .| .||. || | .. .. |||| .||| .. ||.|| | ||||| .| | || .| || .| |||.|... |||||
keefrllee.svgpsetsegdkkhntsknrytnilpvnhtrvqlkkiqdkegsdyinanyidga.ypkqfictqgplpntiadfwrmvwenrcriivmls
PIMEGEEEACAQYWPKEGTIE-----------FGEFTISVREewGHQSFSRKLL--LIRNNKNNMLRRLAHFQVDGWSNDDITSCNEG------AIINTM
| | .|||.. | || ... . | | |... || . | ....| .|| . .| . .| |
resencrikcdrywpeqiggeqfsiygngnevfgtysvelve..viqdpereiitrnirltfegetrditqyqyegwpdhnipdhtqpfrqllhsitnrq
NlvKTLQRKSPNSPILMHCSNMIGRSAVFCAAMATVDQ
| . . | ||..||| .||. ||.|. . .
n..qiipssdrnvpiivhcsagvgrtgtfctavimmkk
|
|||||||||
subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 280-512 | 2.6e-23 | 77.2 | In-house | 47-287 (305) | alignment | ||
Range on Protein: 280-512
Range on HMM: 47-287/305.0
QHPRKNRYQEILPTDQWRVHLKSESP-DYINAVFIPSYKNDKGFIIAQSPLRETRRDFWKMIFDREITTIVMLSPIMEGEEEACAQYWPKE--GTIEFGE
|. ||||... |. ||.|.. | .|| | .. . | | || .|.|| .| ||| | .. . .| || ..| . |..|.. . ..|| |
qeagknrykdvgcldnnrvklegpwpheyihanyvstptnpkrfictqaplektcadfwymclqdkveaifmlcnllekgakkcleyfaskdkdvlefee
--FTISVREEWG-HQSFSR-------KLLLIRNNKNNMLRRLAHFQVDGWSNDDITSCnEGAIINTmnLVKTlqrKSPNSPILMHCSNMIGRSAVFCAAM
|||. | .| . . |. . . |. .|. | . . . . ||.. | |. .. || .||| |||.
kgqkisvkfessvtlkfrkdakakvtetvlviegpgekarkvthyhwidwpdrgvpaa.dlailel..leka...rpskgpivvhcsagigrtgsvvmle
ATVDQMKSSSVVDV-FQTVKNMRVNLPGAVQNKGQYKMIHTLAAAYV
.||. . ... . .. .| . ..| || ..| . |.
yildqllagqiiedtdkilqkireqrnnsiqtdaqylfvhqvilnyf
|
|||||||||
subfamily_PTPN12_pd | Subfamily PTPN12 | 6-91 | 2.9e-23 | 77.2 | In-house | 79-167 (290) | alignment | ||
Range on Protein: 6-91
Range on HMM: 79-167/290.0
DEQSQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSRGSEDY--GPFTVTLQKETTSN-SFIIRELTLHYNT
|....|||.|||| .|. |||||.|. . .||. .. | ..|| .|||..| |. |.|.|||..| . . |.|| |... .
vegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCerYWpeegeeelefgefevtleeekavdddflirtLkveaqk
|
|||||||||
subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 6-90 | 9.6e-23 | 75.5 | In-house | 60-148 (270) | alignment | ||
Range on Protein: 6-90
Range on HMM: 60-148/270.0
DEQSQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSRGSE----DYGPFTVTLQKETTSNSFIIRELTLHYN
|....||||..|||. |. .||||.|.||. ||||.|.|.|. | ||..|||.. | .| .|. ..|. .. .|...|.|...
dgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkekvkledgkikvlalseekeegyiltrlrleek
|
|||||||||
subfamily_PTPN23_pd | Subfamily PTPN23 | 9-91 | 9.9e-23 | 75.3 | In-house | 82-166 (288) | alignment | ||
Range on Protein: 9-91
Range on HMM: 82-166/288.0
SQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSRGS--EDYGPFTVTLQKETTSNSFIIRELTLHYNT
. ..||||.||. |. |||.||...|. ||||.. .| . |...|||.. . .|...|||....... .. |.|.|. .
cPdfiatqaPlqstlnDFWlmvyeqkssviVmllskeelgkpkvdrYwPedkgetvkfgdlsvtlksvretethvervlkletld
|
|||||||||
subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 123-248 | 1.2e-22 | 75.7 | In-house | 186-313 (319) | alignment | ||
Range on Protein: 123-248
Range on HMM: 186-313/319.0
LITHYQFIDWLEYG-PQPPINSLVKFNKI-ISNQTEHKKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMREQRMMMIQTLDQYMLVHE
|| . | | ..| |. |.. . .|. .. |... .||||||.| ||||..| . . .. |. .|. .| .|.|| ..| | ||....
kitqfhflGwpdvGvpdypsdlmrlvkkvrhltskenhranivvhcsaGvGrtGvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiys
AVLEQALCGDTQIVACDLQNTISSLSSS
|.||. | | .... |. . ||.
alleehlfghsdvampdfpayleelsnk
|
|||||||||
subfamily_PTPN3_pd | Subfamily PTPN3 | 122-224 | 1.8e-22 | 74.6 | In-house | 171-273 (280) | alignment | ||
Range on Protein: 122-224
Range on HMM: 171-273/280.0
LLITHYQFIDWLEYGPQPPINSLVKFNKIISNQTEHKKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMREQRMMMIQTLDQYMLVHEA
|.. |...| . | .....| . . .. . |. |.|||||.| |||| .| . .. .. . ....| ||.||.|..|| .|| .| ||
rkilqlqylaWpdhgvPddsadflefvervrklrsgkeePvvvhCsaGigrtGvlilletalalieaaepvypldivrtmrdqramlvqtasqykfvCea
VLE
.|.
ilk
|
|||||||||
subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 123-247 | 2.1e-22 | 75.0 | In-house | 150-276 (284) | alignment | ||
Range on Protein: 123-247
Range on HMM: 150-276/284.0
LITHYQFIDWLEYG-PQPPINSLVKFNKI-ISNQTEHKKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMREQRMMMIQTLDQYMLVHE
|. . | | ..| |. |.. . .|. .. |... .||||||.| ||||..| . . .. |. .|. .| .|.|| ..| | ||....
kirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrtgvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiys
AVLEQALCGDTQIVACDLQNTISSLSS
|.||. | | .... |. . ||.
alleehlfghsdvalpdfpayleelsn
|
|||||||||
subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 283-511 | 2.8e-22 | 73.7 | In-house | 57-288 (305) | alignment | ||
Range on Protein: 283-511
Range on HMM: 57-288/305.0
RKNRYQEILPTDQWRVHLKSESP-DYINAVFIPS-YKNDKGFIIAQSPLRETRRDFWKMIFDREITTIVMLSPIMEGEEEACAQYWPKE-GTIEFGEFTI
|||||.. || |.|. || ||| | .. .| || || || .| .|| |. .. . |||| .| |||||| | |
tknryqdvpcqdqsavkldkpspsdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkveqivmlcktvelgklkcaqywpaaqgeklelksgi
SVREEWGHQSFSRKLLLIRN-----NKNNMLRRLAHFQVDGWSNDDITSCNegaiINTMNLVKTLqRkSPNSPILMHCSNMIGRSAVFCAAMATVDQMKS
| . | . . | . . . |.| | . . |. . ...|. .. | . ||..||| |||. | ....
vvenvsgskpmerdaeiqitllnltysgdqkmsvrhlqwtewpdrgvppck....ltslellsai.r.gskvpivvhcsagigrtgtivaieyilekiae
S-SVVDVFQTVKNMRVNLPGAVQNKGQYKMIHTLAAAY
.. . . || .| . ..|| || .|| . |
nkpcppmpelvkalrdqrafsiqndvqylfihrvmlny
|
|||||||||
0051082 | (Phosphotyrosine protein) phosphatases II | 305-505 | 3.6e-22 | 74.0 | In-house | 3-146 (151) | alignment | ||
Range on Protein: 305-505
Range on HMM: 3-146/151.0
PDYINAVFIPSYkndkgFIIAQSPLRetrrDFWKMIFDREITTIVMLSPIMEGEeeACAQYWPKEGtiefgeftisvreewghqsfsrklllirnnknnm
.||||. .. .. ... . || ||.... . |.|||.| . .| . |..|.|..|
sdyinfsyvtgg.....lyrsggpla....dflellkelgiktivnlrseeerg..ycpeylpelg..................................
lRRLAHFQVDGWSNDDITSCnegaiINTMNLVKTLQRKSPNSPILMHCSNMIGRSAVFCAAMATVdQMksssvVDVFQTVKNMRVNLPGAVQNKGQYKMI
... |.....|.. .. . ..... . | .. .| |.|.||| .||.....|.. .. |....... .| ||.|| . |. ..
.ievlhipildwpdpglpls.....fdavleflellldkkngpvlvHCsaGkgRTGtlvalylml.lg.....vsleealeeyrlkrpgvvqpnqqflfq
H
.
l
|
|||||||||
subfamily_PTPN14_pd | Subfamily PTPN14 | 8-90 | 1.5e-21 | 71.6 | In-house | 91-177 (300) | alignment | ||
Range on Protein: 8-90
Range on HMM: 91-177/300.0
QSQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSRGS----EDYGPFTVTLQKETTSNSFIIRELTLHYN
....||..||||. || |||.|||... |||||. .|| . |. .|.|. .| ..| | || . ..|.|.| . |.|..
kersyivaqgPleltvqdfWqmvWeqgvqlivmlteeeedgkeksfkyfPkleskkktvefgkfkvttkfsedsdsvittglklkhl
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 123-244 | 1.8e-21 | 71.0 | In-house | 90-212 (440) | alignment | ||
Range on Protein: 123-244
Range on HMM: 90-212/440.0
LITHYQFIDWLEYGPQPPINSLVKFN-KIISNQTEHKKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMREQRMMMIQTLDQYMLVHEA
. .|.. | . | ..|. . .| . .||..||||.| |||| | . . ...| ||| ... ||..| |.|| .|| .||||
tlkqyhyqgwpdkgvpkfagpvlkmiqdvnesqekagngpllvhcsagagrtgviiavdsilreakrsdqidifsfinsmrnnrpqmvqtpeqyafvhea
VLEQALCGDTQIVACDLQNTISS
||| ||||| |. |. . .
vlegllcgdtliledditerveq
|
|||||||||
subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 8-88 | 2.1e-21 | 71.2 | In-house | 90-169 (315) | alignment | ||
Range on Protein: 8-88
Range on HMM: 90-169/315.0
QSQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSRgSEDYGPFTVTLQKETTSNSFIIRELTLH
. ..|||.|||. .| ||||.|..|. |||||.| |. . |. .||| . ||..|||...| . . .| |.
kkrryiaaqgpnvasvkdfwrlvfeedigkivmltnlvegekrkaekywpdk.kviyGkitvtrkseevnteytvrtlsvv
|
|||||||||
subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 10-89 | 2.3e-21 | 70.5 | In-house | 86-167 (515) | alignment | ||
Range on Protein: 10-89
Range on HMM: 86-167/515.0
QKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPS--RGSEDYGPFTVTLQKETTSNSFIIRELTLHY
. |||.|||.. .| ||||.|.||. .|.|.|||.|. .|||..||| | .| . | | . |.|.||.
kayiasqgPnkasvddfWrlvlqenvttiamvtklkegdkikcgkyWPdkpgdsvkfGsikvelvsleactggikrkltvlk
|
|||||||||
0044763 | (Phosphotyrosine protein) phosphatases II | 302-508 | 3e-21 | 71.3 | In-house | 15-167 (178) | alignment | ||
Range on Protein: 302-508
Range on HMM: 15-167/178.0
SESPDYINAVFIPSYkndkgFIIAQSPLretrRDFWKMIFDREITTIVMLSPIMEGEEEACAQYWPKEGTiefgeftisvreewghqsfsrklllirnnk
|. |||||..| . ..... | |..... . ||.||.|.. .|. . | .|||.|
lersdyinaseilpg.....lylgslpp....addlellkelgithivnlteelelgflkcdpywpeeag..............................
nnmlrrlahFQVDGWSNDDITSCN-EGAIINTMNLVKTLQRkSPNSPILMHCSNMIGRSAVFCAAMATVDQmkSSSVVDVFQTVKNMRvnlPgAVQNKGQ
.|. . .| . .. . .......... ....|.| ||| .|||....|| . . |. .... |...| | .|.| ||
.........iqylhipipDhgvpdllehflefvefieeald.ekggpvlVHCsaGvgRsgtlvaaylmkkl..glsleeaielvrerR...p.ivpnpgq
YKMIHTLA
.. .. ..
lrqLyefe
|
|||||||||
0049772 | (Phosphotyrosine protein) phosphatases II | 280-512 | 4e-21 | 71.5 | In-house | 45-280 (314) | alignment | ||
Range on Protein: 280-512
Range on HMM: 45-280/314.0
QHPRKNRYQEILPTDqWRVHLKS---ESPDYINAVFIPSYkndKGFIIAQSPLRETRRDF----------WKMIF--DREITTIVM--------------
.. ||||..||| | ||.|.. .. ||||| .. .. . ||..| || .| || |.|.. |. . .|||
lnrdknryldilpad.nrvilpglpvsgsdyinasyvdgf...lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivmsrdevladelsrLd
-------LSPIMEGEeeacaqywpkegtieF----------GeftisvreewghqsfsrkllL-------IrnnkNNMLRRLAHFQVDGWSNDditscNE
| ..... .. .. .. |...| . .
aAlgKtpllildgng...............neptaadlellk....................eelydpelf....erlgikylripvpDgsap.....ll
GAIINTMNLVKTLqrkSPNSPILMHCSNMIGRSAVFCAAMATVDQMKSsSVVDVFQTVKNMRVNLP--GAVQNKGQYKMIHTLAAAYV
. ....... ....|.|.||. .||...|..|. . ... |. .... |...| | |.... || .|. |.
edfdeflefieea...dkggpvlvHCkaGkgRtgtfvvaaylmkllgv.sleealedvrlkRpinpnpgfieqleqyefilealleyl
|
|||||||||
subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 10-91 | 4.4e-21 | 70.3 | In-house | 92-172 (297) | alignment | ||
Range on Protein: 10-91
Range on HMM: 92-172/297.0
QKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRiKCSQYWPSRGSEDYGPFTVTLQKETTSNSFIIRELTLHYNT
...|.|| | . || |||.||..|.. .||||....| . || .||. .|. .| .|.|. . . || |||.. .
hrlittqmPmkatvadfWamvldeqvstivmlnddnerdk.kcaryWsdkgvttfGdvsvvllsvsereGfikrelevtkgk
|
|||||||||
subfamily_PTPN9_pd | Subfamily PTPN9 | 121-227 | 4.5e-21 | 70.1 | In-house | 172-291 (297) | alignment | ||
Range on Protein: 121-227
Range on HMM: 172-291/297.0
TLLITHYQFIDWLEYGPQPPINSLVKFNKIISNQ------------TEH-KKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMREQRMM
. .||.||. | .|| .||... . . .. . | .. |||||||.| ||||.|| . ... ... .|. .| .|.||
srkvthfqflsWPdyGvPssaaslldvlekvrekqalavkelgdewkghpsgPPivvhcsaGiGrtGtfitldiclsrleevgtvdvvetvkllrtqraf
MIQTLDQYMLVHEAVLEQAL
.||| .||.. . |||| ||
siqtpeqyefcylavleyal
|
|||||||||
subfamily_PTPRN_pd | Subfamily PTPRN | 3-87 | 5.6e-21 | 69.5 | In-house | 93-178 (297) | alignment | ||
Range on Protein: 3-87
Range on HMM: 93-178/297.0
NKDDEQSQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSRGSEDYGPFTVTLQKET-TSNSFIIRELTL
..| .. |||||||| || |||.|||.. .. ||.||.|.|. .|..||| ||| |. . | | | .. ...| . |
ldhdprapayiatqgplastvadfwqmvweqGvvvivnltrleeegvkqckrywpdeGsevyhiyevhlvsehiwcddylvrsfyl
|
|||||||||
subfamily_PTPN13_pd | Subfamily PTPN13 | 6-90 | 7.3e-21 | 69.6 | In-house | 73-160 (273) | alignment | ||
Range on Protein: 6-90
Range on HMM: 73-160/273.0
DEQSQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSRGSED---YGPFTVTLQKETTSNSFIIRELTLHYN
... .|||.|||| || |||.|||. || |.|.|. .|. ..|| .|||.. .. .. ..|.| | . ..| .|.|... .
gkdeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvkchrywPesknkklkvsnrlevellkvqkldgfvvralavkds
|
|||||||||
subfamily_PTPN13_pd | Subfamily PTPN13 | 121-224 | 7.7e-21 | 69.6 | In-house | 165-267 (273) | alignment | ||
Range on Protein: 121-224
Range on HMM: 165-267/273.0
TLLITHYQFIDWLEYGPQPPINSLVKFNKIISNQTEhKKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMREQRMMMIQTLDQYMLVHE
. ..| .|..| ..| ..|..| . . . . ..||||||||.| ||.|..| . . . .|. .| .|||| ..|| |||..|..
srevahlnfvkwPdhgvPssaaellqfvaevrrlqt.dagPivvhcsaGiGrsGtlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvyk
AVLE
|.||
aile
|
|||||||||
PTPc_DSPc_SM00012 | 409-508 | 1.1e-20 | 69.2 | In-house | 3-103 (105) | alignment | |||
Range on Protein: 409-508
Range on HMM: 3-103/105.0
AHFQVDGWSNDDITSCNeGAIINTMNLVKTLQRKSP-NSPILMHCSNMIGRSAVFCAAMATVDQMKSS-SVVDVFQTVKNMRVNLPGAVQNKGQYKMIHT
|... ||.. . . .|..... ||. ..|| ..|.. |||. .||...|.|. ..|.... . ||.||.|| .| ||.||.. || ....
khyhytgwpdhgvPees.dsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylflyr
LA
al
|
|||||||||
subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 6-87 | 1.4e-20 | 68.5 | In-house | 48-128 (239) | alignment | ||
Range on Protein: 6-87
Range on HMM: 48-128/239.0
DEQSQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSRGSeDYGPFTVTLQKETTSNSFIIRELTL
| . |||||| . . |||||.|||. | ||||| | | . || |||| | | . |||.| .||| . .
dgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdsts.kycnlrvtlrktevfadyiirtfvm
|
|||||||||
subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 6-87 | 1.4e-20 | 68.5 | In-house | 47-127 (239) | alignment | ||
Range on Protein: 6-87
Range on HMM: 47-127/239.0
DEQSQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSRGSeDYGPFTVTLQKETTSNSFIIRELTL
| . |||||| . . |||||.|||. | ||||| | | . || |||| | | . |||.| .||| . .
dgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdsts.kycnlrvtlrktevfadyiirtfvm
|
|||||||||
subfamily_ptpA1_pd | Subfamily ptpA1 | 8-180 | 1.6e-20 | 68.3 | In-house | 87-250 (418) | alignment | ||
Range on Protein: 8-180
Range on HMM: 87-250/418.0
QSQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSR-GSEDYGPFTVTlqkettsNsfiirELtlhYNTMMGNLRSKIVNPTGR
...|.||||| |. |||||||.... ||||.. |. |||| .||| . | |.. . | |. . | .| | .|
ypkqfictqgplpntiadfwrmvwenrcriivmlsresencrikcdrywpeqiggeqfsiygng.......n.....ev...fgtysvelveviqdpere
IDPNKkEYYSSAQSTLLITHYQFIDWLEYGPQ---PPINSLV-----KFNKIISnqTEHKKGPIVVHCSTGGGRTGAFIGMS
| . . | ||.||. | .. |. |. . |.|| . .. ||.||||.| ||||.|
iitrn.irltfegetrditqyqyegwpdhnipdhtqpfrqllhsitnrqnqiip..ssdrnvpiivhcsagvgrtgtfctav
|
|||||||||
subfamily_PTPN12_pd | Subfamily PTPN12 | 123-224 | 2.2e-20 | 67.7 | In-house | 171-275 (290) | alignment | ||
Range on Protein: 123-224
Range on HMM: 171-275/290.0
LITHYQFIDWLEYGPQPPINSLVKFNKIISNQTEHKKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESI---IDIPAVVTIMREQRMMMIQTLDQYMLVH
.. ... .| . | ..||... . . . |... |.||||| | ||||. | . . .| | .|. .|. .|.|| ..|| .|| ||.
kvyqfhYtaWPDhgvPssaksllelielvrelqesedaPlvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvy
EAVLE
.||.|
kavae
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 4-90 | 8.1e-20 | 65.9 | In-house | 70-160 (297) | alignment | ||
Range on Protein: 4-90
Range on HMM: 70-160/297.0
KDDEQSQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSRGSED--YGPFTVTLQKETT--SNSFIIRELTLHYN
|.|. ||| .||||..|| |||..|... .|||..||||| | || |||| | | . | .|. . |. ||.| |
pdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrdkcapywpsvvqerlkagdvvveflsstsdefdrviltelqliyr
|
|||||||||
0048076 | (Phosphotyrosine protein) phosphatases II | 96-223 | 1.4e-19 | 65.7 | In-house | 36-140 (145) | alignment | ||
Range on Protein: 96-223
Range on HMM: 36-140/145.0
LrskivnptgridPNKKEYYSsaqstLLITHYQFIDWLEYGPQPPINSLVKFNKIISNQTEHKkGPIVVHCSTGGGRTGAFIGMSCSIKdaltESiIDIP
| . .|... |...|....| .|... .. | .| ..| . ... ||..|||| | ||||..... . .. .. ....
l............tselelle.....rlgiqylylpwpDhgvpdllellleflefieealkeg.gpvlVHCsaGvgRtgtlvaaylmll....lg.vsle
AVVTIMREQRMMMIQTLDQYMLVHEAVL
.. .|.||...... .|. ..|..|
ealelvrsqrpgavpnpgqlrflyefel
|
|||||||||
subfamily_PTPN23_pd | Subfamily PTPN23 | 118-226 | 2.2e-19 | 64.4 | In-house | 167-280 (288) | alignment | ||
Range on Protein: 118-226
Range on HMM: 167-280/288.0
AQSTLLITHYQFIDWLEYG-PQPPiNSLVKFNKIISN----QTEHKKGPIVVHCSTGGGRTGAFIGMSCSIKDALT-ESIIDIPAVVTIMREQRMMMIQT
|. . ..| |. | |.| |. | ..|..| . . . . .. | |.|||||.| ||||.| . . ... . . ..||. || .|||| |.|.
adavksvshlqltsWpelGvPasP.etllqfldevesayeavqrksktPlvvhCsaGvgRtgvfalvyaavrelekgnglldiiqvvsrlreqRrfmvqe
LDQYMLVHEAVLEQA
.|. . |||||.|
keqlkfsyeavleaa
|
|||||||||
subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 10-87 | 2.4e-19 | 64.1 | In-house | 94-171 (310) | alignment | ||
Range on Protein: 10-87
Range on HMM: 94-171/310.0
QKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSRG-SEDYGPFTVTLQKETtSNSFIIRELTL
. .| .||||. |..|||||..||.| .|..| | |. | || |||| | .| || || |. |. | | .|..
stficsqgplqhtiidfwrmifqeraesilllckvgeegrpkcvgywpslgvtetygcirvtnlses.seefeicnlav
|
|||||||||
subfamily_PTPN14_pd | Subfamily PTPN14 | 122-223 | 4.2e-19 | 63.6 | In-house | 183-293 (300) | alignment | ||
Range on Protein: 122-223
Range on HMM: 183-293/300.0
LLITHYQFIDWLEYGPQPPINSLVKFNKII----SNQT-----EHKKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMREQRMMMIQTL
. | |..|| . | . ... ... . . . . ...| |..|||| |.|||| | |. .. |||. |....|||||...|||
rtvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseveskeskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLreqrmllvqtl
DQYMLVHEAVL
|| |.....
aqYkfvYkvli
|
|||||||||
subfamily_egg_pd | Subfamily egg | 11-234 | 1.2e-18 | 61.9 | In-house | 84-280 (307) | alignment | ||
Range on Protein: 11-234
Range on HMM: 84-280/307.0
KYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDlrIKCSQYWPSRGSEDYG----PFTVTLQKETTSNS--FIIRELTLhyntMMGNlrskivnpt
..| .| || || ||||||.||. ||||| .| .| ||| |. . .. | | . .| | . |.
efilaqaplkntvddfwrmvfqeevqyivmltsrkes..erceyywpkaesdslvtvpGslrienlkvdskadplfrvtklkl....vGgd.........
gridpnkkeyyssaQSTLLITHYQFiDWLEYGP-QPPINSLvkfnkiisNQTEHKKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIP--AVVTIM
. . . |.| |. . . |.. | . . |.||.. | ...... . .. . | | . | .
..............deerflehwqg.dvnnssdvysplrvl........rklrnlskpvvvqdilGvskaatlvaieiallsllrGpitkslvlravvfl
REQRMMMIQTLDQYMLVHEAVL--EQALCGDTQIV
| .| . ... .|..|. || . . | .. .
rlrrrlsvesvllylfvyrlvlfffrdvigsakel
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 9-224 | 1.4e-18 | 61.3 | In-house | 106-342 (349) | alignment | ||
Range on Protein: 9-224
Range on HMM: 106-342/349.0
SQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSrgsEDYGPFTVTLQKeTTSNSFIIRELTLHYNTMMGNLRSKIVNPTGRID
.|||||| || || ||.... .. .. |.. .| || .|| .| .|| || . .. .. .|.. | . | ..
ekkyiatqaPlPstvddfykvillngvklvlsLnddkelslekcdiywqe...lsysnitvklqn.sslyianvqGnslrvstvkdtdndndnnkknCdl
PNKKEYYS---SAQSTLLITHYQFIDWLEYG----PQPPINSLVKFNKIISNQT------EHKKGPIVVHCSTGGGRTGAFIGMSCSIK--DALTESI--
|.. . . . .. . |. .||. . |. ...| |..| .. . . ...||||.| |||| .. . . |..
pddddddaillavekPyellqlqvknwldlslllnPisilqalevkndliddlfarlyldtdqlstllvhcsaGcGrtGvlvtldlllsileplqnesnk
ID--------IPAVVTIMREQRMMMIQTLDQYMLVHEAVLE
|. | .| ..| ||. |.| | |.. ..||.|.
iklqallkDlisiivnelrkqrismvqnlaqfiaiyealLk
|
|||||||||
0048179 | (Phosphotyrosine protein) phosphatases II | 109-220 | 1.9e-18 | 62.0 | In-house | 42-139 (144) | alignment | ||
Range on Protein: 109-220
Range on HMM: 42-139/144.0
PNKKEYYssaqstllITHYQFIDWLEYGPQPPINSLVKFNKIISNQTEhKKGPIVVHCSTGGGRTGAFIGMSCSIkdalTESiIDIPAVVTIMREQRMMM
|. | . ...|....| .|. . .. | .| ..| . | ..||..|||| | ||||... . . .. ... .. .|..|...
peflere........giqylhlpwpDhgvpdllellleflefieeale.eggpvlVHCsaGvgRtgtlvaaylmk....klg.lsleealalvrsrrpga
IQTLDQYMLVHE
... .|.. ..|
vpnpgqlrfLle
|
|||||||||
subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 215-423 | 1.9e-18 | 61.0 | In-house | 28-237 (244) | alignment | ||
Range on Protein: 215-423
Range on HMM: 28-237/244.0
YMLVHEAVLEQALCGDTQIVACDLQNTISSLSSSDNASVTGFEAQFNVLEQVSVPPQDAVCDVA--RQHPRKNRYQEILPTDQWRVHLKSES--PDYINA
.| .||| . . | ...| |||| . . .|.. | . |. .| | . ||| || | || | | ||||
eflqtnavlsanatknryinilpfdetrvilssskkegsdyinanyiqgsqniirpdpsvmkdafnpnnswknregaglpfdfnrvplskgsmgntyina
VFIPSYKNDKGFIIAQSPLRETRRDFWKMIFDREITTIVMLSPIMEGEEeacaqYWPKEGTIEFGEFTISV--REEWGHQSFSRKLLLIRNNKNNMLRRL
|. .|..| || .| |||||...| . .|.| . | .| ||| .|. | |.| . . | | . |. . |
sfvgclgrtaeyiltqhpladtsmdfwkmmlerhvnvlvvlgsveeede.....ywpdseplewyeeditvtltdrdefknikasnleiesdmneshqal
AHFQVDGWSNDDITS
. ||. | | |
tmfqisnwpsdgttp
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 278-432 | 1.9e-18 | 61.2 | In-house | 25-186 (319) | alignment | ||
Range on Protein: 278-432
Range on HMM: 25-186/319.0
ARQHPRKNRYQEILPTDQWRVHLKSE----SPDYINAVFIPSYKNDK-GFIIAQSPLRETRRDFWKMIFDREITTIVMLSPIMEGEEEACAQYWPKE---
|.|. ...| . || |.. . |..| .. |.. . .| || .| .. |||...... .|| |. . | . ||.|.| .
PvtskdksrvinvvPlPetrvvlqrigdddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlselGikvcaeylPtketl
-GTIEFGEFTISVREEWGHQSFSRKLLLIRNNKNNMLRRLAHFQVdGWSNDDITScNEGAIINT
.| .|.. ..... .. . ||... .... | |.|. | . .. . .| |.|
dntslyGdilvtlkgrevkdryaistlllkrvdkeesrelthywy.kwleaevPa.eeaaliam
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 278-385 | 2.7e-18 | 60.8 | In-house | 44-166 (350) | alignment | ||
Range on Protein: 278-385
Range on HMM: 44-166/350.0
ARQHPRKNRYQEILPTDQWRVHLK-----------S-ESPDYINAVFI----PSYKNDKGF--IIAQSPLRETRRDFWKMIFDREITTIVMLSPIMEGEE
. ||||..||| .. ||.|| | .. ||||| .. .| . . .| | .|.||..| ||.|.|. ... |..|.. .| .
GvelfaknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnl
EACAQYWPKEGtieFGEFTISVREEW
| | .||.. . . ..|. . . |
ekcyrYWqegs...ydditvklaskw
|
|||||||||
subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 10-85 | 2.9e-18 | 60.5 | In-house | 94-172 (290) | alignment | ||
Range on Protein: 10-85
Range on HMM: 94-172/290.0
QKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSRGSE--DYGPFTVTLQKETTSNSFIIRE-L
.| |||.| ||.|.|||| |||. ||||| .| || . ||.||.| . | .| .||. .|.. .. ||. |
amfiltqGalkdtvidiwrmvlqekvaaivmlceliedGkakceqyypekeGevltfGeitvlcseeddkdaniikktl
|
|||||||||
subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 279-503 | 3.3e-18 | 60.8 | In-house | 17-250 (290) | alignment | ||
Range on Protein: 279-503
Range on HMM: 17-250/290.0
RQHPRKNRYQEILPTDQwRVHLK----SESPDYINAVFIpSYKNDKGFIIAQSPLRET-------RRDFWKMIFDREITTIVMLSPIMEGEEE----ACA
..| ..|.. | .. || || . ||| | .. .. |. .|. |||. .. .|| |. . ... .||| .| ... |||
kkhemdqRlevpLveat.rvvLkgygkrfnddyiHAnrv.tcpnglrliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCa
QYWPKE--GTIEFGEFTISVREEWGHQSFSRKLLLIRNNKNNMLrRLAHFQVDGWSNDDITSCNegaiINTMNLVKTLQrkSPNSPILMHCSNMIGRSAV
.| |.. . . |. .|.. . .. . .. |... .... . . | .. ||.. . . . ..|..... ..|...|| . | |||.
kYvpesvgeelkfkgltvkCkskekeddvetRelvvkfddeeef.tvtHsllkgWnklnvqedt....ktllsliqkvk..asktpvivHcvdGiSrsAa
FCAAMATVDQMK-SSSVVDVFQTVKNMRVNLPGAVQNKGQYKM
. | . .|. | . . .|..| . |.... ..
laaiilgyQkiaetsgsvkledvlkalrkqralaitsalelaf
|
|||||||||
subfamily_egg_pd | Subfamily egg | 253-512 | 4.8e-18 | 59.9 | In-house | 13-270 (307) | alignment | ||
Range on Protein: 253-512
Range on HMM: 13-270/307.0
VTGFEAQFNVLEQVSVpPQDAVCDVARQHPRKNRYQEILPTDQWRVHLKSE----SPDYINAVFIPSYKNDKGFIIAQSPLRETRRDFWKMIFDREITTI
| ..| ...|||... . .. . | | . . | ||.|. . . |.| | . ||.||.||..| |||.|.| |. |
vqelerrlevleesvd.eislttaasdnnlekarskrvhckdssrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvddfwrmvfqeevqyi
VMLSPIMEGeeEACAQYWPKEG--TIEF--GEFTISVREEWG--HQSF-SRKLLLIRNNKNNmlRRLAHFQVDgwsndDItscNEGAIINTMNLVKTLQR
|||. | | | |||| .. . | . | . | || |. .... | | |.| | | . . ..... |..
vmltsrkes..erceyywpkaesdslvtvpGslrienlkvdskadplfrvtklklvGgddee..rflehwqgd.....vn...nssdvysplrvlrklrn
KSpnSPILMHCSNMIGRSAVFCAAMATV-DQMKSS-SVVDVFQTVKNMRVNLPGAVQNKGQYKMIHTLAAAYV
| |..... . . ..|.. |. .. . .. | ..|. .| . . .|. .| ... | . ..
ls..kpvvvqdilGvskaatlvaieiallsllrGpitkslvlravvflrlrrrlsvesvllylfvyrlvlfff
|
|||||||||
subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 317-505 | 1.2e-17 | 58.8 | In-house | 2-197 (199) | alignment | ||
Range on Protein: 317-505
Range on HMM: 2-197/199.0
KNDKGFIIAQSPLRETRRDFWKMIFDREITTIVMLSPIMEGEEEACAQYWPK--EGTIEFGEFTISVREEWGHQSFSRKLLLIRNNKN--NMLRRLAHFQ
| .. .| .| ||||| |||.|... |||. | . ||| || ..| ...... . .. |.. || | ..|.|
kgqrryiatqhplretmadfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyq
VDGWSNDDITS--CNEGAIINTMNLVKTLQRkSPNSPILMHCSNMIGRSAVFCAAMATVDQMKS--SSVVDVFQTVKNMRVNLPGAVQNKGQYKMIH
| . | .. . .. | .. ..|...|||. | . || | | . .||||.|. | .| | . .|..|.
ftswkekttpnvalfvgfvvasrevskkyeq.ekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiy
|
|||||||||
subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 319-505 | 1.6e-17 | 58.4 | In-house | 3-196 (198) | alignment | ||
Range on Protein: 319-505
Range on HMM: 3-196/198.0
DKGFIIAQSPLRETRRDFWKMIFDREITTIVMLSPIMEGEEEACAQYWPK--EGTIEFGEFTISVREEWGHQSFSRKLLLIRNNKN--NMLRRLAHFQVD
.. .| .| ||||| |||.|... |||. | . ||| || ..| ...... . .. |.. || | ..|.|
qrryiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqft
GWSNDDITS--CNEGAIINTMNLVKTLQRkSPNSPILMHCSNMIGRSAVFCAAMATVDQMKS--SSVVDVFQTVKNMRVNLPGAVQNKGQYKMIH
| . | .. . .. | .. ..|...|||. | . || | | . .||||.|. | .| | . .|..|.
swkekttpnvalfvgfvvasrevskkyeq.ekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiy
|
|||||||||
subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 268-512 | 3.7e-17 | 56.9 | In-house | 35-279 (303) | alignment | ||
Range on Protein: 268-512
Range on HMM: 35-279/303.0
VPPQDAVCDVArQHPRKNRYQEILPTDQWRVHLKSESpdYINAVFIpSYKNDKGFIIAQSPLRETRRDFWKMIFDREITTIVMLSPIMEGEEEACAQYWP
.||. . . . |||. ... |. .|.| | || | .. . .| |..| || | |||.|| .. . ...| | .. .|
lppsvsknqfv.knmdknrfvdvicldhskvklsdss..yihasyl.eldsskkailtqlplshtaadfwqmiieqkvkcvlllltdseydklggdsvfp
KEG-TIEFGEFTISVREEWG---HQSFSRKLLLIRNNKNNMLRRLAHFQvdGWSNDDITSCNEGAIINTMNLVKTLQRK-SPNSPILMHCSNMIGRSAVF
.. ..| | .| | | . .. |.| . | . . . . |.. | ..| | ... . .... || |...| . ||. |
rnqdflkfeersirvgefkrvelgdgwvlkvlsvsngdyksflhvhhyk..awphnsipsdgspkfvkqiwqlqsvlrkysdstptvymslsgcgragtf
---C-AAMATVDQMKSSSVVDVFQTVKNMRVNlpgAVQNKGQYKMIHTLAAAYV
| .. .. | .| ....|.| |. |||| |. ...|| | .|
alfetahlslhseqasldlvkclenvrngrlh...avqnlsqfsvvytllaehv
|
|||||||||
subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 124-226 | 4e-17 | 57.1 | In-house | 158-259 (267) | alignment | ||
Range on Protein: 124-226
Range on HMM: 158-259/267.0
ITHYQFIDWLEYGP-QPPINSLvkFNKIISNQTEHKKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMREQRMMMIQTLDQYMLVHEAV
.| | . | .| .. | | . || | |.||.|| | ||.|.|. . .. | ||.. || . .|.||. ...|...|. .|| .
vtlyyykkwnintnnkpylkpl..fgilaknqlengnrPlvvacsdGvGrsGtflvidsqleraktegvsdifdflrkirsqriglvdtkeryiyihell
LEQA
| |
aeya
|
|||||||||
subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 123-224 | 4.3e-17 | 57.0 | In-house | 153-262 (270) | alignment | ||
Range on Protein: 123-224
Range on HMM: 153-262/270.0
LITHYQFIDWLEYGPQPPIN------SLVKFNKII-SNQTEHKKG-PIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMREQRMMMIQTLDQ
..|... .| . | . . .|.| . . ..|..|. |..|||| | |||| .| . .. ... .|. |... .|..|| ..|. .|
rlvHfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcsaGvgRtGtlialDiavrlLeetkkvdvlaiieelRkdRmalvqhpeq
YMLVHEAVLE
| ....||.|
yeflykavve
|
|||||||||
subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 274-373 | 4.5e-17 | 56.6 | In-house | 45-147 (310) | alignment | ||
Range on Protein: 274-373
Range on HMM: 45-147/310.0
VCDVARQHPRKNRYQEILPTDQWRVHL---KSESPDYINAVFIPSYKNDKGFIIAQSPLRETRRDFWKMIFDREITTIVMLSPIMEGEEEACAQYWPKEG
. ... |||| ... |. ||.| || ||| | .. . . || .| ||. | |||.|||. .|..| ..| | ||| |
tyeaykkymhknrysdvvcldtsrvklkidksryedyihanyvktnylrstficsqgplqhtiidfwrmifqeraesilllckvgeegrpkcvgywpslg
TIE
|
vte
|
|||||||||
subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 8-86 | 8.7e-17 | 55.8 | In-house | 78-158 (287) | alignment | ||
Range on Protein: 8-86
Range on HMM: 78-158/287.0
QSQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSRGSE-DYGPFTVTL-QKETTSNSFIIRELT
. ...||.|||. || ||||.|...........|. |. | || .||| | | ..|.| ... . . .| |
ddeafiaaqgPiaatvrdfwravletrsasvitmtreveearlkcykywPerevPmrvGGysvvlldydikePeygvralr
|
|||||||||
subfamily_PTPRN_pd | Subfamily PTPRN | 118-225 | 3.1e-16 | 53.9 | In-house | 183-291 (297) | alignment | ||
Range on Protein: 118-225
Range on HMM: 183-291/297.0
AQSTLLITHYQFIDWLEYGPQPPINSLVKFNKIISNQTEHKKGPIVVHCSTGGGRTGAFIGMSCSIKDALT-ESIIDIPAVVTIMREQRMMMIQTLDQYM
.. | .| . |. | | | . .||..| . . . ||||||| | ||||..| . .. | ||| | . .|.|| ...| ||.
tsetrtvtqfhflswpeegvPasaksllefrrkvnksyrGrscpivvhcsdGaGrtGvyilidlvlnrllkGvkeidiaatlehlrdqrpglvktkdqfe
LVHEAVLEQ
.. || |.
faltavaee
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 10-97 | 4.3e-16 | 53.3 | In-house | 236-321 (440) | alignment | ||
Range on Protein: 10-97
Range on HMM: 236-321/440.0
QKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDlriKCSQYWPSR-GSEDYGPFTVTLQKETTSNSFIIRELTLHYNTMMGNLR
. .|||| ||| ||.||||.| . . .|.|| .|.. || ||| | .||||| . | .| | |.|. . ..|
nafiatqmpldstvldfwrlvhdyristiimlnqlndk...tcsiywpvntrsvtfgpftvghkgsenmnrvkvrtlelkykeevheir
|
|||||||||
subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 4-87 | 4.5e-16 | 53.9 | In-house | 85-169 (325) | alignment | ||
Range on Protein: 4-87
Range on HMM: 85-169/325.0
KDDEQSQKYIATQGPLDRTVVDFWRMV--WQekaCAIVMLTKLQEDLRIKCSQYWPSR--GSEDYGPFTVTLQKETTSNSFIIRELTL
.|| . . ..|.| || |. |.||.| |. |..|... . .|..||| . | .|.. | |. . .. | | .
rddkkkdvflaaqaPltatindlWrlvldWr...csvvvvlneldlgkdrcavywpkemgksktfGglevklrtieeisdyvhrvldv
|
|||||||||
subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 10-91 | 6e-16 | 52.9 | In-house | 81-164 (281) | alignment | ||
Range on Protein: 10-91
Range on HMM: 81-164/281.0
QKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSR--GSEDYGPFTVTLQKETTSNSFIIRELTLHYNT
. || |||| | |||||.|||.. ||||| .. | | ||..|.| .. ..|. . | .|.. | | |.
rgyiltqgpkketradfwrmiwqenttaivmlcqfletnrekcaeyfprnahcclqfdklsvsyedstvnkslvttrlnlsyeg
|
|||||||||
subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 124-224 | 1.3e-15 | 52.3 | In-house | 138-238 (239) | alignment | ||
Range on Protein: 124-224
Range on HMM: 138-238/239.0
ITHYQFIDWLEYGPQPPINSLVKFNKIISNQTEHKKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMREQRMMMIQTLDQYMLVHEAVL
. .|.| | . | ... . . |.... | |.|||.| ||||||. . . ...| . .|| | .||.| |.|| .||...| |||
vyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlrqakkqktvdifnyvkairedrphmvqtseqyvfihlavl
E
|
e
|
|||||||||
subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 124-224 | 2e-15 | 51.6 | In-house | 139-239 (239) | alignment | ||
Range on Protein: 124-224
Range on HMM: 139-239/239.0
ITHYQFIDWLEYGPQPPINSLVKFNKIISNQTEHKKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMREQRMMMIQTLDQYMLVHEAVL
. .|.| | . | ... . . |.... | |.|||.| ||||||. . . ...| . .|| | .||.| |.|| .||...| |||
vyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlrqakkqktvdifnyvkairedrphmvqtseqyvfihlavl
E
|
e
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 6-87 | 4.1e-15 | 50.3 | In-house | 68-153 (319) | alignment | ||
Range on Protein: 6-87
Range on HMM: 68-153/319.0
DEQSQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSR----GSEDYGPFTVTLQKETTSNSFIIRELTL
|. |||.| .|. . ||||.||. .. || ||.|.| .|..|.|.. . . || . |||.. . . ..| | |
ddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlselGikvcaeylPtketldntslyGdilvtlkgrevkdryaistlll
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 151-222 | 6.7e-15 | 49.5 | In-house | 237-311 (319) | alignment | ||
Range on Protein: 151-222
Range on HMM: 237-311/319.0
ISN--QTEHKKGPIVVHCSTGGGRTGAFIGMSCSIKDALTE-SIIDIPAVVTIMREQRMMMIQTLDQYMLVHEAV
||. |....||.||||| | |||| | .|. . .||| .| .|..| ..| .|| ... .
issrsgtresqGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefiykvl
|
|||||||||
subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 10-61 | 8.5e-15 | 49.2 | In-house | 96-147 (305) | alignment | ||
Range on Protein: 10-61
Range on HMM: 96-147/305.0
QKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSRGS
...|..|||||.|. .|| || |.| |||| | | ..||.||||
krficaqgpldqtidefwwmviqnkveqivmlcktvelgklkcaqywpaaqg
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 148-225 | 3.1e-14 | 47.5 | In-house | 216-294 (297) | alignment | ||
Range on Protein: 148-225
Range on HMM: 216-294/297.0
NKIISNQTEH-KKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMREQRMMMIQTLDQYMLVHEAVLEQ
.. | ..|. .. ...||||.| ||.| . .. . | |. |...|.|||| ...|||.|. |...|||..
lqleslraemprnayllvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqtleqfellydavlkk
|
|||||||||
subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 122-223 | 4.3e-14 | 47.0 | In-house | 168-274 (287) | alignment | ||
Range on Protein: 122-223
Range on HMM: 168-274/287.0
LLITHYQFIDWLEYGPQPPINSLVKFNKII-----SNQTEHKKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMREQRMMMIQTLDQYM
.. .....| . . | .|..| . .. . ||.|||...| ||.| .. . .. . .|. ||| .||.| ..|. |.
rvvkqldllswPdkvlaPtavglirfvldvkqhielardasevGPlvvhddvGiGrsGillatlvlvsrledlGrvdvaavvirlreyraalvqavvqlr
LVHEAVL
|. ||.
llyealv
|
|||||||||
subfamily_Sponge-PTP7_pd | Subfamily Sponge-PTP7 | 163-225 | 1.2e-13 | 45.2 | In-house | 1-63 (69) | alignment | ||
Range on Protein: 163-225
Range on HMM: 1-63/69.0
VVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMREQRMMMIQTLDQYMLVHEAVLEQ
|||||.| ||||.|| . . .| ..|| | || | ||. ..||..|.|. |
vvhcssGtGrtGtfiaimvemarikseklvdifnnvqymrkcrpmmvmneneymfihdalvea
|
|||||||||
subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 407-512 | 1.4e-13 | 45.0 | In-house | 279-385 (392) | alignment | ||
Range on Protein: 407-512
Range on HMM: 279-385/392.0
RLAHFQVDGWSNDDITsCNEG--AIINTMNLVKTLQRKSPNSPILMHCSNMIGRSAVFCAAMATVDQMKSSSVVDVFQTVKNMRVNLPGAVQNKGQYKMI
.. .| || . | ... . ||. . . ||.|| ||. |||.|| . |. ||.||||| .| . || . .| ..
tvtqyqfhgwpkhgsd.qqsgarsllkliravkgstnskkefsilvhclsgagrtgvfctameciaqiaegdsvdifqtvkilradrmqfvqteeeyafv
HTLAAAYV
. . |.
ydvireyl
|
|||||||||
subfamily_Sponge-PTP-4_pd | Subfamily Sponge-PTP-4 | 304-423 | 1.8e-13 | 44.9 | In-house | 12-128 (130) | alignment | ||
Range on Protein: 304-423
Range on HMM: 12-128/130.0
SPDYINAVFIPSYKNDKGFIIAQSPLRETRRDFWKMIFDREITTIVMLSPIMEGEEeacaqYWPKEGTIEFGE--FTISVREEWGHQSFSRKLLLIRNNK
.|||| |. . . .. .| || .| |||||...| . .|.| . | .| ||| .|. | .... . . . . | | ..
gntyinasfvGllgrtaeylltqhpladtsmdfwkmmleryvnvlvvlgsveeede.....ywpdsePlewyeediivtltdrdefknikasnleiesdl
NNMLRRLAHFQVDGWSNDDITS
|. . |. ||. | | |
neshqaltmfqisnwpsdgttp
|
|||||||||
subfamily_Sponge-PTP-7_pd | Subfamily Sponge-PTP-7 | 162-225 | 2e-13 | 44.5 | In-house | 1-64 (69) | alignment | ||
Range on Protein: 162-225
Range on HMM: 1-64/69.0
IVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMREQRMMMIQTLDQYMLVHEAVLEQ
.|||||.| ||||.|| . . .| ..|| | || | ||. .|...|.|. |
mvvhcssgtgrtgtfiaimvemarikseklvdifnnvqymrkcrpmmvmneieyifihdalvea
|
|||||||||
subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 332-476 | 2.4e-13 | 44.7 | In-house | 40-183 (255) | alignment | ||
Range on Protein: 332-476
Range on HMM: 40-183/255.0
TRRDFWKMIFDREITTIVMLSPIMEGEEEACAQYWPKE--GTIEFGEFTISVREEWGHQSFSRKLLLIRNNKNNMLRRLAHFQVDGWSNDDITSCNEgAI
| |...| . ...|||. | . | | .|.| | . . . .... . . . .. . . . |.. || . . |
tvdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdeklkladvnvtttkssadvvlrtleitstlgekkkthtvkhysykGWieknaPelar.ei
INTMNLVktlqRKSpnSPILMHCSNMIGRSAVFCAAMATVDQ----MKSSS
| . .| |.| ....|||. ||||| | | . .. ..
lnilkvv....rds..ksvvvhCstGiGrsaafvlaelvyqkmirsldtte
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 406-506 | 3e-13 | 43.9 | In-house | 89-188 (440) | alignment | ||
Range on Protein: 406-506
Range on HMM: 89-188/440.0
RRLAHFQVDGWSNDDITSCnEGAIINTMNLVKTLQRKSPNSPILMHCSNMIGRSAVFCAAMATVDQMKSSSVVDVFQTVKNMRVNLPGAVQNKGQYKMIH
| | ... .|| . . | ... .. |. | |. |.|.|.||| ||..| | . . . | | .|.| ...|| | | || || ..|
rtlkqyhyqgwpdkgvpkf.agpvlkmiqdvnesqekagngpllvhcsagagrtgviiavdsilreakrsdqidifsfinsmrnnrpqmvqtpeqyafvh
T
e
|
|||||||||
subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 9-92 | 3.8e-13 | 44.1 | In-house | 4-89 (199) | alignment | ||
Range on Protein: 9-92
Range on HMM: 4-89/199.0
SQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSR--GSEDYGPFTVTLQKETTSNSFIIRELTLHYNTM
..||||| || |. |||.|||. . |||. | . . |||. |. || ..|| . || . | | | ||
qrryiatqhplretmadfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnntt
|
|||||||||
subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 10-92 | 4.1e-13 | 44.0 | In-house | 4-88 (198) | alignment | ||
Range on Protein: 10-92
Range on HMM: 4-88/198.0
QKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSR--GSEDYGPFTVTLQKETTSNSFIIRELTLHYNTM
..||||| || |. |||.|||. . |||. | . . |||. |. || ..|| . || . | | | ||
rryiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnntt
|
|||||||||
subfamily_eak_pd | Subfamily eak | 285-438 | 5.1e-13 | 43.1 | In-house | 56-212 (332) | alignment | ||
Range on Protein: 285-438
Range on HMM: 56-212/332.0
NrYQEILPTDQWRVHLKSE---SPDYINAVFIPSYKNDKGFIIAQSPLRETRRDFWKMIFDREITTIVMLSPIMEGEEEACAQYWPKEG--TIEFGEFTI
| .|.| |. |.| | |||| . . . .|.. . . ||.|.... .||.| .| . | .|.|... ..|| . .
n.vvkivpydrylvrltssqlnrlGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledvelkleksdkyfpdktreelkfGildv
SVREEWGHQSFSRKLLLIRnnKNNMLRRLAHFQVDGWSNDDITSCNEG-AIINTMNLVKT
.| .. . .|| .. | | |. |..| ||.. .. .. |. ..| | .
erkefvkrniletrllels..kGnethrvlhykvfGwtettlpkyedflalrkvmkevGv
|
|||||||||
subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 272-489 | 7.5e-13 | 42.8 | In-house | 34-256 (312) | alignment | ||
Range on Protein: 272-489
Range on HMM: 34-256/312.0
DAVCDVARQHPRKNRYQEILPTDQWRVHLKSESPDYINAVFIPSYKNDKGFIIAQSPLRETRRDFWKMIFDREITTIVMLSPIMEGEEEACAQYWPK-EG
|. | . ||| .| |. | | . || | |. . . |...|.|| .| ||.. . |.|..|. ..| | ||.| |
dsectaflkfkdlnrypniqcwdrgrftlagdenfyihanfvkictkperfvctqgplentcthfwqlalslgstsiillcgfvedgsekcakyisdivg
TIEFGEFTI---SVRE-EWGHQS---FSRKLLLIRNNKNNMLRRLAHFQVDGWSNDDITSCNEGAiintMNLVKTLqrKSPNSPILMHCSNMIGRSAVFC
... . . .. | | | .| . ..| . . .| |.| | . . . | . |. .. | . |.. ||| .||. ..
fvdledhrvyteycteieiggkskdkithrvlkvvvkatgqesklnhyqwaswpdhgmpdscdta....lrllsav..kkdkkpviahcsagvgrtgtla
---AAMATVDQMKSSSVVDVFQTVKNMRV
. .|.. . . | |.| ... |
liesmiaalrhprkqnvkdsfvllrkdra
|
|||||||||
subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 8-83 | 1.2e-12 | 42.4 | In-house | 74-152 (285) | alignment | ||
Range on Protein: 8-83
Range on HMM: 74-152/285.0
QSqKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSRGSE--DYGPFTVTLQ--KETTSNSFIIR
|| ||.||||| |. |||.|..||| . ..|| | | ||. |.| . | .| . .|| || . |.
qs.tyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyypeklgevvkfgkyeitlteckeeaiagtiln
|
|||||||||
subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 117-226 | 1.6e-12 | 41.7 | In-house | 183-289 (305) | alignment | ||
Range on Protein: 117-226
Range on HMM: 183-289/305.0
SAQSTLLITHYQFIDWLEYGPqPPInSLVKFNkIISNqTEHKKGPIVVHCSTGGGRTGAFIGMSCSIK-DALTESIIDIPAVVTIMREQRMMMIQTLDQY
| . .. . | |. .| . | || | .. ..| | |||||||.| ||||. . . .. | . .| .| .|.|| . ||. ||
sgdqkmsvrhlqwtewpdrgv.ppc.kltsle.llsa.irgskvpivvhcsagigrtgtivaieyilekiaenkpcppmpelvkalrdqrafsiqndvqy
MLVHEAVLEQA
. .| .|.
lfihrvmlnyf
|
|||||||||
subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 326-502 | 1.7e-12 | 41.4 | In-house | 97-278 (302) | alignment | ||
Range on Protein: 326-502
Range on HMM: 97-278/302.0
QSPLRETRRDFWKMIFDREITTIVMLSPIMEGEEEACAQYWPKE--GTIEFGEFT---ISVREEWG----HQSFSRKLLLIRNNKNNMlRRLAH---FQV
| ..|. .| .| . ... .| |. ..|.||. ||.|. .. |...||..| .||... .|| . |.|.| .. . ..
ivpkkstlekhwalieqynvaivvqlcsfvedeekkcaeyysdkvggelkfgrytvktvsvktdleeftdkksfklytveiknekkkk.kvkktvdilaf
DGWSNDDITSCNEgaiiNTMNLVKTLqrKSPNSPILMHCSNMIGRSAVFCAAMATVDQMKSSSVVDVFQTVKNMRVNLPGAVQNKGQYK
.| . . ......| .| .|.|||. .||. . | .. . | |. . |. .| ||||.. |
sawpdhGapkeay....taldilkfc..esykknvlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqdeqqli
|
|||||||||
0048076 | (Phosphotyrosine protein) phosphatases II | 398-508 | 4.3e-12 | 41.4 | In-house | 37-139 (145) | alignment | ||
Range on Protein: 398-508
Range on HMM: 37-139/145.0
RNNKNNMLRRLAHFQVDGWSNDDITSCNeGAIINTMNLVKTLQRKspNSPILMHCSNMIGRSAVFCAAMatvdQMKSSSvVDVFQTVKNMRVNLPGAVQN
..... | ... .| .. . ... .......... . |.| ||| .||.....||. |.. . |....... .| ||||.|
tselellerlgiqylylpwpDhgvpdll.ellleflefieealke..ggpvlVHCsaGvgRtgtlvaay....lmlllg.vsleealelvrsqrpgavpn
KGQYKMIHTLA
||..... .
pgqlrflyefe
|
|||||||||
subfamily_hpo-7_pd | Subfamily hpo-7 | 329-475 | 6.3e-12 | 39.9 | In-house | 43-188 (263) | alignment | ||
Range on Protein: 329-475
Range on HMM: 43-188/263.0
LRETRRDFWKMIFDREITTIVMLSPIMEGEEEACAQYWPKE--GTIEFGEFTISVREEWgHQSFSRKLLLIR--NNkNNMLRRLAHFQVDGWSNDDITSc
| .| |...| . ...|||. | . | | .|.| | . . . .... . .. . | |. .. .. . |.. || .
lvqtidkfyqtivqtktevvvmLcDfneegvekcssyfPlekdekqklanvnvcttkvq.sdvllktlellstlge.KkkthtvkhysykgWiekndpe.
NEGAIintMNLVKtLQRKSpnSPILMHCSNMIGRSAVFCAAMATVDQM----KSS
. | .|..| . |.| .. .|||. ||||| | | .| . .
larei...lnilk.varns..kslvvhcstGiGrsaafsvaElvyqkmirsldtt
|
|||||||||
subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 123-226 | 6.4e-12 | 40.1 | In-house | 172-271 (288) | alignment | ||
Range on Protein: 123-226
Range on HMM: 172-271/288.0
LITHYQFIDWLEYGPQPPINSLVKFNKIIsnqtEHKKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMREQRMMMIQTLDQYMLVHEAV
.. . . .| . | | ... ... . . |||||.|.| ||||..| . .. . . . |. ... .||.|. ||| ||. || |
ivkilhlleWdddgvPenylsplrllevl....kslqkPivvhssaGvGrtgtlililialeslrlddflgirsllaklreerfkaiqtemqylyvhrcv
LEQA
||.
leel
|
|||||||||
0048179 | (Phosphotyrosine protein) phosphatases II | 410-507 | 9.4e-12 | 40.4 | In-house | 51-140 (144) | alignment | ||
Range on Protein: 410-507
Range on HMM: 51-140/144.0
HFQVDGWsnDDITSCNE-GAIINTMNLVKTLQRksPNSPILMHCSNMIGRSAVFCAAMatvdQMKSSSvVDVFQTVKNMRVNLPGAVQNKGQYKMIHTL
... .| .| . ............. .. |.| ||| .||.....|| || ........ .| ||||.| ||..... .
qylhlpw..pDhgvpdllellleflefieeale..eggpvlVHCsaGvgRtgtlvaay....lmkklg.lsleealalvrsrrpgavpnpgqlrfLley
|
|||||||||
subfamily_hpo-7_pd | Subfamily hpo-7 | 5-178 | 1e-11 | 39.2 | In-house | 33-173 (263) | alignment | ||
Range on Protein: 5-178
Range on HMM: 33-173/263.0
DDEQSQKYIAtqgpLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSRGSEDYGPFTVTLqkeTTSN--SfiireltlhyntmmgnlrsKIVN
| .. . |. | .|. |.... | |. .|||. .|. . |||.|.| | |.. .|.. | ...
dkkrknlysl....lvqtidkfyqtivqtktevvvmLcDfneegvekcssyfPlekdekqklanvnv...cttkvqs...................dvll
PTGRIdpnkKEYYSSAQSTLLITHYQFIDWLEY-GPQPPINSLvkfnKIISNQTEHKkgPIVVHCSTGGGRTGAFIG
| . .. . . | ..||.. |.| .|. ....| .|. .. | ..|||||||.||. ||
ktlel....lstlgeKkkthtvkhysykgWiekndpelareil....nilkvarnsk..slvvhcstGiGrsaafsv
|
|||||||||
subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 155-224 | 2.8e-11 | 37.6 | In-house | 212-281 (290) | alignment | ||
Range on Protein: 155-224
Range on HMM: 212-281/290.0
TEHKKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMREQRMMMIQTLDQYMLVHEAVLE
. ||.|||||.| ||||.|. . ... | .|. .| .|. |. .| ||... |..|.
lrkasGpvvvhcsaGiGrtGtfvaievglqilldGkeldlldlvralrnsrlnsvqvdiqylalveilld
|
|||||||||
subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 118-219 | 4.6e-11 | 37.3 | In-house | 91-197 (199) | alignment | ||
Range on Protein: 118-219
Range on HMM: 91-197/199.0
AQSTLLITHYQFIDWLEYGpQPPINSLVKF---NKIISNQTEH-KKGPIVVHCSTGGGRTGAFIGMSCSIKD--ALTESIIDIPAVVTIMREQRMMMIQT
|| |.|||| | | | . .| | . .|.. | | |..|||| | | || |. . .. |..|. | .|. | .| .
ppstreishyqftswkekt.tpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiiss
LDQYMLVH
|..| ...
lqhynfiy
|
|||||||||
subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 118-219 | 4.6e-11 | 37.3 | In-house | 90-196 (198) | alignment | ||
Range on Protein: 118-219
Range on HMM: 90-196/198.0
AQSTLLITHYQFIDWLEYGpQPPINSLVKF---NKIISNQTEH-KKGPIVVHCSTGGGRTGAFIGMSCSIKD--ALTESIIDIPAVVTIMREQRMMMIQT
|| |.|||| | | | . .| | . .|.. | | |..|||| | | || |. . .. |..|. | .|. | .| .
ppstreishyqftswkekt.tpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiiss
LDQYMLVH
|..| ...
lqhynfiy
|
|||||||||
subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 118-225 | 5.4e-11 | 36.7 | In-house | 163-268 (281) | alignment | ||
Range on Protein: 118-225
Range on HMM: 163-268/281.0
AQSTLLITHYQFIDWLEYgpQPPINSLVKFnKIISnQTEHKKGPIVVHCSTGGGRTGAFIGMSCSIKDALTE-SIIDIPAVVTIMRE-QRMMMIQTLDQY
| ||||. . .| .. | | | | . ||. . . | |.|||.| ||.|... . ... . .. || .|. .| | .|||.||
egetrlithwlwkewpdw..qvpessevml.kilr.kirarstppvihcsagvgrsgtlmaveialqsihshftlpdikqivshlrvtgraasvqtlqqy
MLVHEAVLEQ
||. . .|.
mliwkvlldf
|
|||||||||
subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 17-217 | 7.5e-11 | 36.0 | In-house | 98-279 (302) | alignment | ||
Range on Protein: 17-217
Range on HMM: 98-279/302.0
GPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSRGSE--DYGPFTVTlqkeTTSNSFIIRELTLHYNTMMGNLRSKivnptgridPNKKEY
| |. .| .. | . . .| |... || ||..|. . . .| .||. | | . |.| . .. .. | .||.
vpkkstlekhwalieqynvaivvqlcsfvedeekkcaeyysdkvggelkfgrytvk....tvsvktdleeftdkksfklytveik.........nekkkk
ysSAQSTLLITHyqFIDWLEYG-PQPPINSLvkfnKIISNqTEHKKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMREQRMMMIQTLD
. |. | . | | ..| |. . ..| .|. | | ..||||.| ||||... . |. ... . |. .|. .|. | .|. .
..kvkktvdila..fsawpdhGapkeaytal....dilkf.cesykknvlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqdeq
QYML
| .
qliy
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 316-380 | 2.2e-10 | 34.5 | In-house | 232-294 (440) | alignment | ||
Range on Protein: 316-380
Range on HMM: 232-294/440.0
YKNDKGFIIAQSPLRETRRDFWKMIFDREITTIVMLSPImegEEEACAQYWPKE-GTIEFGEFTIS
| . . || .| || | |||... | .|.||.|| . .. .|. ||| . .. || ||.
yskknafiatqmpldstvldfwrlvhdyristiimlnql...ndktcsiywpvntrsvtfgpftvg
|
|||||||||
subfamily_Sponge-PTP-7_pd | Subfamily Sponge-PTP-7 | 449-506 | 2.8e-10 | 34.4 | In-house | 2-59 (69) | alignment | ||
Range on Protein: 449-506
Range on HMM: 2-59/69.0
LMHCSNMIGRSAVFCAAMATVDQMKSSSVVDVFQTVKNMRVNLPGAVQNKGQYKMIHT
..||| ||. | | | . ..|| .||.| |. || | | |. .| .||
vvhcssgtgrtgtfiaimvemarikseklvdifnnvqymrkcrpmmvmneieyifihd
|
|||||||||
subfamily_Sponge-PTP7_pd | Subfamily Sponge-PTP7 | 450-506 | 3.1e-10 | 34.2 | In-house | 2-58 (69) | alignment | ||
Range on Protein: 450-506
Range on HMM: 2-58/69.0
MHCSNMIGRSAVFCAAMATVDQMKSSSVVDVFQTVKNMRVNLPGAVQNKGQYKMIHT
.||| ||. | | | . ..|| .||.| |. || | | |. .| .||
vhcssGtGrtGtfiaimvemarikseklvdifnnvqymrkcrpmmvmneneymfihd
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 440-512 | 5.2e-10 | 33.5 | In-house | 242-315 (319) | alignment | ||
Range on Protein: 440-512
Range on HMM: 242-315/319.0
QRKSPNSPILMHCSNMIGRSAVFCAAMATVDQMKSS-SVVDVFQTVKNMRVNLPGAVQNKGQYKMIHTLAAAYV
... . |. .|||. .||. . |. .. ... | ||. |.| .| . ||..| ||..|. . |
gtresqGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefiykvlseya
|
|||||||||
subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 122-225 | 1.6e-09 | 32.2 | In-house | 167-269 (285) | alignment | ||
Range on Protein: 122-225
Range on HMM: 167-269/285.0
LLITHYQFIDWLEYGPQPPINSLVKFNKIISnQTEHKKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMREQRMMMIQTLDQYMLVHEA
| . | | | . .... | . . . |. ||.||||.| ||| .|.|. . . . |.. .| || |. .|. |.....
lymnhvqvpwwpdqlapedarpmielykwvk.kvnpkekpicvhcsagvgrtatfvgidyatirimenpniemldivremramrfqavqshmqflflyvv
VLEQ
..|
lmey
|
|||||||||
subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 9-91 | 2.4e-09 | 31.6 | In-house | 71-152 (267) | alignment | ||
Range on Protein: 9-91
Range on HMM: 71-152/267.0
SQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDlriKCSQYWPSR--GSEDYGPFTVTLQKETTSNSFIIRELTLHYNT
...|.||.||. |. ||. .. ..| ||.||| .| . ..|| . .. | .|| | | . | | |...
knafivtqdplkntitdfltvihdqkvpvivlltkvftd...nirlfwPPkmgqakkyqdltvehslekeendyqiitlelkfkn
|
|||||||||
subfamily_eak_pd | Subfamily eak | 8-88 | 7.6e-09 | 29.4 | In-house | 91-173 (332) | alignment | ||
Range on Protein: 8-88
Range on HMM: 91-173/332.0
QSQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSRG--SEDYGPFTVTLQKETTSNSFIIRELTLH
.||| | . . | ||.|| ..|. |||.| . | | .|.| .. ..| . |. .. | . | | |.
vGrkyiltGiasedkvfafwqmvleqkspaivqlledvelkleksdkyfpdktreelkfGildverkefvkrniletrllels
|
|||||||||
0038934 | (Phosphotyrosine protein) phosphatases II | 94-179 | 1.1e-08 | 30.5 | In-house | 48-135 (194) | alignment | ||
Range on Protein: 94-179
Range on HMM: 48-135/194.0
GNLRSKIVNPTGRIDPNK-KEYYSSAQSTLLITHYQFIDWLEYGPQPPINSLVKFNKIISNQTEH-KKGPIVVHCSTGGGRTGAFIGM
|... |. . || .. . ||. . . .| . . ..|. |... | .| ... .. ..| ..||| | |||| ...
rylkllnvklglvidltnteryYdpeefekagieylklpfpddgtvPsleillrfldlvdeflnedpggvvaVHCkaGlgRtGtlvaa
|
|||||||||
subfamily_PTPDC1_pd | Subfamily PTPDC1 | 124-220 | 1.1e-08 | 29.7 | In-house | 83-170 (182) | alignment | ||
Range on Protein: 124-220
Range on HMM: 83-170/182.0
ITHYQFiDWLEYGPqPPINSLVKFNKIISNQTEHKkgPIVVHCSTGGGRTGAFIGMSCSIKDALTESiidipAVVTIMREQRMMMIQTLDQYMLVHE
|..|.| | .|| ....... |... ... . ||| | |||| | .. || . ....|..| ||| .| ||.|
iyvynf.gwkDygv.asleriLdivkvvafalqeg..kvavhChaGlGrtGvliacylvyakrltae.....kaiklvrskrpksiqtreqvelvke
|
|||||||||
subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 301-354 | 1.2e-08 | 28.9 | In-house | 66-120 (347) | alignment | ||
Range on Protein: 301-354
Range on HMM: 66-120/347.0
KSESPDYINAVFIPSYKNDKGFIIAQSPLRETRRDFWKMIFDREITTIVML-SPI
.. |||| | . .| .|..| || .| ||||||.. .| .| . ||
addvetyinashikfdnaskeyiltqyplpdtvrdfwkmvsvtkvtqvvtifepi
|
|||||||||
subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 157-224 | 1.7e-08 | 28.4 | In-house | 221-288 (310) | alignment | ||
Range on Protein: 157-224
Range on HMM: 221-288/310.0
HKKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMREQRMMMIQTLDQYMLVHEAVLE
..|| |||||.| .|... . . .|. . .|. |.| .. .|.. ||| ||.... .
vrhgpcvvhcsagkdrlyvvvalklkidkldrglkvdaeevktellksraiciqtelqyliidrvrii
|
|||||||||
subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 124-225 | 1.9e-08 | 28.4 | In-house | 178-275 (312) | alignment | ||
Range on Protein: 124-225
Range on HMM: 178-275/312.0
ITHYQFIDWLEYGPQppiNSLVKFNKIISNQTEHKKgPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMREQRMMMIQTLDQYMLVHEAVL
. |||. | ..| .| ...| || |.. |||.| ||||... . | .. . ..| .| .... ||. . .||
lnhyqwaswpdhgmp...dscdtalrllsavkkdkk.pviahcsagvgrtgtlaliesmiaalrhprkqnvkdsfvllrkdrarsvrvfpqyvyalrcvl
EQ
|
ef
|
|||||||||
subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 120-223 | 5.2e-08 | 27.4 | In-house | 156-256 (290) | alignment | ||
Range on Protein: 120-223
Range on HMM: 156-256/290.0
STLLITHYQFIDWLEYGPQPPINSLVKFNKIISnqteHKKGPIVVHCSTGGGRTGAFIGMSCSIKDAL-TESIIDIPAVVTIMREQRMMMIQTLDQYMLV
. .||... .| . |. .|.. . . .| |..||| | | |. . . |.. . . .|. .|.|| ..|.. .. |
eeftvtHsllkgWnklnvqedtktllsliqkvk....asktpvivHcvdGiSrsAalaaiilgyQkiaetsgsvkledvlkalrkqralaitsalelafv
HEAVL
...
dagiv
|
|||||||||
subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 114-198 | 5.9e-08 | 27.1 | In-house | 108-167 (255) | alignment | ||
Range on Protein: 114-198
Range on HMM: 108-167/255.0
YYSSAQSTLLITHYQFIDWLEY-GPQPPINSLvKFNKIISNQtehKkgPIVVHCSTGGGRTGAFIgmscsikdaltesiidipavV
... . | ..||.. |.| .|. . . | . |.. . | ..|||||||.||. ||. .
tlgekkkthtvkhysykGWieknaPelareil.nilkvvrds...k..svvvhCstGiGrsaafv....................l
|
|||||||||
subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 152-222 | 6.5e-08 | 26.3 | In-house | 211-281 (302) | alignment | ||
Range on Protein: 152-222
Range on HMM: 211-281/302.0
SNQTEHKKGPIVVHCSTGGGRTGAFIGMSCSIKDALTESIIDIPAVVTIMREQRMMMIQTLDQYMLVHEAV
..... . ..|. | || |||. . ... ... | .|. .|.|| ....|.||. .. |.
fakkikadentvivSknGaGRagafltlavaveklqkgkepnikeivksiRsqRpravdslkQyvslyial
|
|||||||||
subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 8-60 | 1.4e-07 | 25.8 | In-house | 80-132 (288) | alignment | ||
Range on Protein: 8-60
Range on HMM: 80-132/288.0
QSQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSRG
.. | .| ||. |. .|.|. .. ||||..| | . | .|.||.
ykrrlicaqaPlngtieelWkmllesdveyivmlcellekGkeksaeyfPskl
|
|||||||||
subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 7-87 | 1.5e-07 | 25.8 | In-house | 32-105 (255) | alignment | ||
Range on Protein: 7-87
Range on HMM: 32-105/255.0
EQSQKYIAtqgpldrTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYWPSRGSEDYGPFTVTLQKETTSNSFIIRELTL
.. . |. || |.... | |. .|||. ..|. . |||.|.| | |.. .|. ..| |..
krknlysl.......tvdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdeklkladvnvtttkssadvvlrtlei
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 284-368 | 1.5e-07 | 25.1 | In-house | 51-155 (349) | alignment | ||
Range on Protein: 284-368
Range on HMM: 51-155/349.0
KNRYQEILPTDQWRVHLKS------------------ESPDYINAVF--IPSYKNDKGFIIAQSPLRETRRDFWKMIFDREITTIVMLSPIMEGEEEACA
||||..||| . || || ||||| . .. .. .| .| | || | ||.|.| .. .. |. | . | |
knrykdilPyehsrvklkkslksskvikastsesdsgklddyinanylkltrisvekkyiatqaPlPstvddfykvillngvklvlsLnddkelslekcd
QYWPK
.|| .
iywqe
|
|||||||||
subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 13-90 | 5.6e-07 | 24.0 | In-house | 63-153 (290) | alignment | ||
Range on Protein: 13-90
Range on HMM: 63-153/290.0
IATQGPLD-------RTVVDFWRMVWQEKACAIVMLTKLQEDLRI----KCSQYWPSRGSE--DYGPFTVTLQKETTSNSFIIRELTLHYN
|.|| |. |. .|| |. |||. .||| . .| . |..| | . | .. .|| .. . . ...|||.....
iltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCakYvpesvgeelkfkgltvkCkskekeddvetRelvvkfd
|
|||||||||
subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 5-50 | 9.9e-07 | 22.6 | In-house | 80-125 (347) | alignment | ||
Range on Protein: 5-50
Range on HMM: 80-125/347.0
DDEQSQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRI
|. |..|| || || || |||.|| | .| . . ..| |
fdnaskeyiltqyplpdtvrdfwkmvsvtkvtqvvtifepikdeai
|
|||||||||
subfamily_CDC14_pd | Subfamily CDC14 | 110-181 | 1.3e-06 | 22.5 | In-house | 220-285 (328) | alignment | ||
Range on Protein: 110-181
Range on HMM: 220-285/328.0
NKKEYYSSAQSTLLITHYQFidWLEYGPQPPINSLVKFNKIISNQtehkKGPIVVHCSTGGGRTGAFIGMSC
||| | . . |. . . | |. . . || .|. . .| |.||| | ||||..|.
nkklYdakkftdaGfdhkDl..ffiDGstPsdaivkkfleiaeka....eGaiavhCkaGLGrtGtLiacyl
|
|||||||||
subfamily_Sponge-PTP3_pd | Subfamily Sponge-PTP3 | 254-326 | 1.5e-06 | 22.3 | In-house | 23-94 (95) | alignment | ||
Range on Protein: 254-326
Range on HMM: 23-94/95.0
TGFEAQFNVLEQVSVPPQDAVCDVArqHPRKNRYQEILPTDQWRVHLKSE-SPDYINAVFIPSYKNDKGFIIAQ
|. .|. . | | . | |||. .|.| | || | . |||||.|. | . .| ||
qefdnefksismtsgapytvgssea..nipknrflnifpydatrvvlttkrdsdyinacfvdgyarkncyiaaq
|
|||||||||
0048567 | (Phosphotyrosine protein) phosphatases II | 133-179 | 2.9e-06 | 21.7 | In-house | 46-97 (157) | alignment | ||
Range on Protein: 133-179
Range on HMM: 46-97/157.0
LEYGpQPPINSLVKFNKIISNQT---EHKKGPIVVHCSTGG---GRTGAFIGM
..| .... |..|.... . |.....|.|||..| |||. .||
fdfG.PlnlailyrFilklnkflkilelagkaiavhckaglkkrgrtatLigc
|
|||||||||
subfamily_DSP23_pd | Subfamily DSP23 | 134-220 | 3.1e-06 | 21.9 | In-house | 61-140 (148) | alignment | ||
Range on Protein: 134-220
Range on HMM: 61-140/148.0
EYGPqPPINSLVKFNKIISnQTEHKKGPIVVHCSTGGGRTGAFIgmSCSIKDaltESIIDIPAVVTIMREQRMMMIQTLDQYMLVHE
.| | | .. .|.| ... ..|.|. . ||| | ||||... .| . | . .. .|..| ..|..| ||..
dyhp.paleqvvefvrvve.eaeekneavsvhcllgrgrtgtml..acylvk...erklaaaeaiaevrrlrpgsvetveqeklvrd
|
|||||||||
0038934 | (Phosphotyrosine protein) phosphatases II | 418-506 | 4.7e-06 | 21.9 | In-house | 88-171 (194) | alignment | ||
Range on Protein: 418-506
Range on HMM: 88-171/194.0
NDDITSCNEGAIINTMNLVKTLQRKSPNSPILMHCSNMIGRSAVFCA-AMATVDQMkssSVVDVFQTVKNMRvnlPGAVQNKGQYKMIHT
||.|. . . . ..||.. ...|. .. || .||.....| .. . .| |. . .... .| |||..| ........
pddgtvPsleillrfldlvdeflnedpggvvaVHCkaGlgRtGtlvaaYLiyrlgm...saeeAialfrekR...pgaipnqdyleallk
|
|||||||||
subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 9-56 | 6e-06 | 20.2 | In-house | 81-128 (312) | alignment | ||
Range on Protein: 9-56
Range on HMM: 81-128/312.0
SQKYIATQGPLDRTVVDFWRMVWQEKACAIVMLTKLQEDLRIKCSQYW
.....|||||. |.. ||... ...|..|. . || ||..|
perfvctqgplentcthfwqlalslgstsiillcgfvedgsekcakyi
|