Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 878-978 | 1.5e-68 | 225.7 | In-house | 201-301 (301) | alignment | ||
Range on Protein: 878-978
Range on HMM: 201-301/301.0
NGIVREPHTILQVIDDVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFKLHSTYA
.|.||||.|.||||||||||||||||||||||||||||||||||||||.||||||||||||||||||.||||||||||||||||||||||||..|.||||
dGvvreprtvLqviddvihrqqkigggpvvVHCSdtVsrsGvYcsvsiglEQckaegVVdvfqvtkavrrskpgaVtTLeqytsiydvidmylqlnstya
N
|
n
|
|||||||||
subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 878-972 | 5.2e-38 | 125.9 | In-house | 191-285 (305) | alignment | ||
Range on Protein: 878-972
Range on HMM: 191-285/305.0
NGIVREPHTILQVIDDVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFKL
.|..... ..|..|..| ..|.| | |..||||..|.|.||...|.||||..|.|.|||||.|.|..|......|.||.||....|..| . .
hGvpqfatsllslikrvqkdqkkdkgvpllVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkmvqtldqYvflhdaldelitc
|
|||||||||
0050432 | (Phosphotyrosine protein) phosphatases II | 823-978 | 1e-36 | 122.2 | In-house | 57-307 (308) | alignment | ||
Range on Protein: 823-978
Range on HMM: 57-307/308.0
EKPCTIGYSEENKPFNRFKNITVYDDNRIILatnpnlDmCQREYINASYVDGY-----------------------------------------------
...... .|||..||.|.| || .|..| | ||||||||||
lleysvallpenkdkNrykdilpydhsRVkl......d.egsdYInAsyvdgyssklprkfIatqgPlpntvedFwrmvweqnvrvIvmLtklvengrek
----------------------------------------------------------SSNGIVREPHTILQVIDDVIHRQqkiGGGPVVVHCSDTVSRS
|. .| .|. .. | ... .|||.|||||. |.|.
caqYwplelgggsleygkftvtllseevlddytvrtleltnlgdgesrtvthfhytnWpdhgvPpspeilldflelvrksl...pggpivVHCsaGvGRt
GVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFKLHSTYAN
|... . ..||| ..|| ||||.. | .|. .||.|.|.||| .|... .|.||. |..|
GtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylflyralleylklkltkln
|
|||||||||
0046845 | (Phosphotyrosine protein) phosphatases II | 823-978 | 3.5e-35 | 117.2 | In-house | 17-282 (284) | alignment | ||
Range on Protein: 823-978
Range on HMM: 17-282/284.0
EKPCTIGYSEENKPFNRFKNITVYDDNRIILATNPNlDMCQREYINASYVDGY-----------------------------------------------
. ...... .||. ||.|.| .||..|..| . .. |. .||||||||||
llslsvallpenlsknRykdilpydhsRVklksldg.dledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqnvrvIVmltelveng
------------------------------------------------------------SSNGIVREPHTILQVIDDVIHRQQK-IGGGPVVVHCSDTV
.|. .| .|. ...| . ... ||||.|||||. |
rekcaqYwplegevltygdftvtllseevkddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrellenlpgggpivVHCsaGv
SRSGVYCSVSIALEQCKAEG---VVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFKLHSTYAN
.|.|... . ..||| ..|| .|||... | .|. .||.|.||||| .|... .|.||. |...
gRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleylklkltlle
|
|||||||||
0040438 | (Phosphotyrosine protein) phosphatases II | 821-976 | 1.5e-34 | 115.1 | In-house | 30-282 (317) | alignment | ||
Range on Protein: 821-976
Range on HMM: 30-282/317.0
GEEKPCTIGYSEENKPFNRFKNITVYDDNRIILATNPNldMCQREYINASYVDGY---------------------------------------------
...... .|||..||...| ||..|..| .. |||||||||.
lkldtysvaelpenkdknrypdilpydhsRVkLsplgg..dldsdYInAsyvdgpnlkrkfIatqgPlpntvedFwrmvweqgvtvivmLteleelgrek
-------------------------------------------------------SSNGIVREPHTILQVIDDVIHRQQkiG-GGPVVVHCSDTVSRSGV
|. | ..|. .. | . .. . ||||.||||. |.|.|.
caqYwplgetltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavreale..dpggpvlVHCsaGvgRtGt
YCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFKLHSTY
.. . ..|||.. || |||... | .|. .||||.|.||| .||.. .|.| . |.
fiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleylkrkltl
|
|||||||||
0039614 | (Phosphotyrosine protein) phosphatases II | 820-973 | 1.9e-34 | 114.9 | In-house | 43-292 (297) | alignment | ||
Range on Protein: 820-973
Range on HMM: 43-292/297.0
SGEEkPCTIGYSEENKPFNRFKNITVYDDNRIILATNPNLDMcQREYINASYVDGYSS------------------------------------------
| . ...|....|||..||.|.| ||..|..| .... |. ||||||||||.
slkp.dysiallpenkdknrykdilpydhsrvklkpedgvdl.dsdYinAsyvdgydlltrkfIatqgPlpetvedFwrmvweqgvtvivmLtklvelgr
-------------------------------------------------------NGIVREPHTILQVIDDVIHRQQKI-GGGPVVVHCSDTVSRSGVYC
.|. . ..|.... | ..... .||||.||||. |.|.|...
kcaqywpeeggtygdftvtllkvehldgytvrtlevtnngesrtvthfqytgwpdhgvppslellleflelvrealaelpkggpvlVHCsaGvgRtGtfi
SVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFKLH
..|||.. || |||... | .|. .||||.|..|| .||.. ...| .
aaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydallellkrk
|
|||||||||
0051299 | (Phosphotyrosine protein) phosphatases II | 824-970 | 3.3e-34 | 114.0 | In-house | 39-286 (288) | alignment | ||
Range on Protein: 824-970
Range on HMM: 39-286/288.0
KPCTIGYSEENKPFNRFKNITVYDDNRIILATNPNldMCQREYINASYVDGYS-----------------------------------------------
...... .||.. ||...| ||..|..| . .. . ||||||.|||
ltlsaallpenleknRysdilpydhsRVkLsvldg..vegsdYinAsyidgynlkrkfIatqgPlpntvedFWrmvweqnvrvIvmltklvelgrekcaq
---------------------------------------------------------SNGIVREPHTILQVIDDVIHRQQkIGGGPVVVHCSDTVSRSGV
.|. | .|. . .|.. .. ||||||||||. |.|.|.
Ywplggsltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdspellldflrlvrkala.sgggpvvVHCsaGvgRtgt
YCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYF
.. . ..||| ..||.|||... | .|. .||.|.|.||| .|... .|.
fialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyealleyl
|
|||||||||
0036941 | (Phosphotyrosine protein) phosphatases II | 824-975 | 4.3e-34 | 113.6 | In-house | 29-282 (297) | alignment | ||
Range on Protein: 824-975
Range on HMM: 29-282/297.0
KPCTIGYSEENKPFNRFKNITVYDDNRIILatnpnlDMCQREYINASYVDGYS-----------------------------------------------
..... ..||.. ||.|.| ||..|..| | ||||||||||.
gslsvallpenleknRykdilpydhtRVkl......ddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqnvtvIvmltelvelgrekcaq
---------------------------------------------------------SNGIVREPHTILQVIDDVIHRQQKI-GGGPVVVHCSDTVSRSG
.|. | ..|. |. | ...... .||||.||||. |.|||
ywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrkvlkllpsggpvlVHCsaGvgRsg
VYCSVSIALEQCK---AEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFKLHST
... . ..|.| . || ||.... | .|. .||||.||||| .|... ...| . |
tfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallellkkklt
|
|||||||||
0047943 | (Phosphotyrosine protein) phosphatases II | 823-970 | 3.7e-33 | 110.6 | In-house | 27-272 (273) | alignment | ||
Range on Protein: 823-970
Range on HMM: 27-272/273.0
EKPCTIGYSEENKPFNRFKNITVYDDNRIILatnpnlDMCQREYINASYVDGYS----------------------------------------------
. ...... .||| .||.|.| ||..|..| .. ||||||||||
lltysvallpenkdknrykdilpydhsrvkl......gdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvweqnvrviVmLtelvelgrekca
---------------------------------------------------------SNGIVREPHTILQVIDDVIHRQQKI-GGGPVVVHCSDTVSRSG
.|. . .|. |..| . .... ..||||||||. |.|.|
qYwpleggelsltygkftvtllseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvrkalealpsngpvvVHCsaGvgRtg
VYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYF
... . ..|.| ..|| |||... | .|. .||.|.|.||| .|... .|.
tfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyealleyl
|
|||||||||
subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 876-976 | 1.2e-32 | 108.0 | In-house | 189-289 (290) | alignment | ||
Range on Protein: 876-976
Range on HMM: 189-289/290.0
SSNGIVREPHTILQVIDDVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFKLHST
|.| | .|.|||.|| ... | | | ...||||||||.||.|.|.. .....|| |||.||||| | | ||| |.| .|| |.... |.. .|
dstgkvtnpqtillvieemyktqrkrgntsivvHCSdtvgrsavfcaaattinkcktegvidvfqvlksqRiqkpgsvqtvqqyqgifqivltyldsfet
Y
|
y
|
|||||||||
0043336 | (Phosphotyrosine protein) phosphatases II | 819-970 | 1e-31 | 105.9 | In-house | 30-277 (278) | alignment | ||
Range on Protein: 819-970
Range on HMM: 30-277/278.0
KSGEEKPCTIGYSEENKPFNRFKNITVYDDNRIILATNPNldMCQREYINASYVDGYS------------------------------------------
| ...|....|||..||.|.| || .|..| .. ||||||||||.
lsfkldtysiallpenkdknrykdilpydhsrvklsllgg..dldsdYinAsyvdgynvprkfiatqgPlpetvedFwrmvwelgvttivmLtelvelgr
----------------------------------------SNGIVR-----------------EPHTILQVIDDVIHRQQkIGGGPVVVHCSDTVSRSGV
.| .| . ..|. . .|..... .|||.||||. |.|.|.
vkcaqYwpggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldflkavreale.dsngpvlVHCsaGvgRTGt
YCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYF
.. . ..||| . || ||.... | .|. .||||.|..|| .|... .|.
fialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyealleyl
|
|||||||||
0045450 | (Phosphotyrosine protein) phosphatases II | 823-970 | 1.6e-31 | 105.6 | In-house | 44-304 (307) | alignment | ||
Range on Protein: 823-970
Range on HMM: 44-304/307.0
EKPCTIGYSEENKPFNRFKNITVYDDNRIILATNPNLdMCQREYINASYV--------DGY---------------------------------------
...|....|||..||.|.| ||..|..| . .. . ||||||| |||
lgeysiallpenkdknrykdilpydhtRVklssldgs.ledsdYiNAsyvrvpllllldgydlkrkfIatqgPlpetvedFwrmlweqgvtvivmltelv
---------------------------------------------------------------SSNGIVREPHTILQVIDDVIHRQQKI-GGGPVVVHCS
|. . ..|. |. | . ... .||||.||||
elgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfeelldfieevrkaleelpkggpvlVHCs
DTVSRSGVYCSVSIALEQCKAEGV---VDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYF
. |.|.|... ..|.| ..||. ||.... | .|. .||||...||| .|... ...
aGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeallell
|
|||||||||
subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 877-979 | 5.3e-30 | 99.4 | In-house | 185-287 (287) | alignment | ||
Range on Protein: 877-979
Range on HMM: 185-287/287.0
SNGIVREPHTILQVIDDVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFKLHSTY
|.| | || ||| ||.. .. |.| | ...|||||||| ||...|.. .....|| |||.||||| | | |||.| | |||. |.|.. .| . .||
stgkvtepqtillvieemyktqrkrgntsivvhCsdtvGrsamfcaaattinkckteGviDvfqvlksqriqkpgsvqtveqykfindivleyldsfety
ANF
..|
sdf
|
|||||||||
0040439 | (Phosphotyrosine protein) phosphatases II | 825-970 | 1.5e-29 | 98.7 | In-house | 2-246 (249) | alignment | ||
Range on Protein: 825-970
Range on HMM: 2-246/249.0
PCTIGYSEENKPFNRFKNITVYDDNRIILATNPNLDMCQreYINASYVDGYS------------------------------------------------
...... .|||. ||...| || .|..| |.| . ||||||.|||
eysvallpenkdknrypdilpydhsrvklsilpglflsd..yinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqy
----------------------------------------------------SNGIVREPHTILQVIDDVIHRQQKI-GGGPVVVHCSDTVSRSGVYCSV
|. . ..|. |. | . .... ||||.||||. |.|.|...
wplggsleygdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaa
SIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYF
..||| . |. ||.... | .|. .||||...||| .|... ...
ylmleqlekelgvdleeavkllrsqRpgavqnpeqyrflyeallell
|
|||||||||
0042113 | (Phosphotyrosine protein) phosphatases II | 826-970 | 5.1e-28 | 93.5 | In-house | 1-243 (245) | alignment | ||
Range on Protein: 826-970
Range on HMM: 1-243/245.0
CTIGYSEENKPFNRFKNITVYDDNRIILATNPNLDMCQreYINASYVDGYS-------------------------------------------------
..... .|||..||...| ||..|..| .. . ||||||||||
ysvallpenkdknrysdilpydhtrvklspdggdldsd..yinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqyw
----------------------------------SNGIVRE-----------------PHTILQVIDDVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSI
.. .|| . ..|.... | . ... ..|||.||||. |.|.|... . .
plgesltygdftvtllseehlddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaayl
ALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYF
.||| ..|. |..... | .|. .||||.|..|| .|... ...
mleqlekelgvsleeavkelrsqRpgavqtpsqyrflyeallell
|
|||||||||
0045098 | (Phosphotyrosine protein) phosphatases II | 824-971 | 2e-26 | 88.4 | In-house | 23-273 (278) | alignment | ||
Range on Protein: 824-971
Range on HMM: 23-273/278.0
KPCTIGYSEENKPFNRFKNITVYDDNRIIlatnpnldmcqrEYINASYVDGYsS----------------------------------------------
.| . ..|...||.|.| || .|.. .||||||.||| .
seitpalylgnldknRykdilpydhsrVk............dYINAsyidgy.pkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaqy
---------------------------------------------------------NGIVREP--HTILQVIDDVIHRQQK------------IGGGPV
.|. .| .|.... . ..... .||||
wpeggsltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpv
VVHCSDTVSRSGVYCSVSIALEQCkaEGVVDVFQVTKAIRRSKPG-AVTTLEQYTSIYDVIDMYFK
.|||| |.|.|... . . ||.. ||.||.... | .|. .|| ||..|||| .|... ....
lVHCsaGvgRtGtlvaaylmlell..eggvdlleavkelrsqRpglavqnleqyrflyefllelll
|
|||||||||
subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 879-977 | 3.8e-26 | 87.0 | In-house | 199-297 (298) | alignment | ||
Range on Protein: 879-977
Range on HMM: 199-297/298.0
GIVREPHTILQVIDDVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFKLHSTYA
|. .. ...|.....| ||. | ||.|.||. | ||| .. .. ||. |.| ||||||| |..|...||||.| |||. ||... ... ....
gvpenatsvldllrkvrasqqqagnkpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavlealdsfndei
|
|||||||||
subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 884-977 | 2e-25 | 84.4 | In-house | 156-249 (250) | alignment | ||
Range on Protein: 884-977
Range on HMM: 156-249/250.0
PHTILQVIDDVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFKLHSTYA
...|.....| ||..| .||.|.|| |.||| .. .. ||. | | |||||.| |..|. .|.||..|||| ..| .| . . . ||
atavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidavlerlkkekvvdvfkvikvlrkdrphavesleqyvfvyeiilkaldsvedya
|
|||||||||
subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 815-877 | 4.3e-25 | 83.0 | In-house | 21-83 (301) | alignment | ||
Range on Protein: 815-877
Range on HMM: 21-83/301.0
THSLKSGEEKPCTIGYSEENKPFNRFKNITVYDDNRIILATNPNLDMCQREYINASYVDGYSS
..||.||.|.||.|.|||||..||||||||||||||||...||||.||||||||||.||||.
ykelkegedksctvglseenkalnrfknitvyddnriilkpkpnldlcqreyinasyidgyse
|
|||||||||
subfamily_PTPRD_pd | Subfamily PTPRD | 878-976 | 1.1e-23 | 78.8 | In-house | 190-287 (564) | alignment | ||
Range on Protein: 878-976
Range on HMM: 190-287/564.0
NGIVREPHTILQVIDDVIHRQqKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFKLHSTY
.|. .. ..|..|..| . . . . ||.||||| | |.|... ... ||. |.|..||..|. ||.|. .. | | ||| |...| . . .|
hgvpesatslLdlirkvraln.epdagPivVhCSaGVGRTGtfividamlerikeektvDiyqyvkalrkqRnamVqteeQYiFiheailealacgnte
|
|||||||||
subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 882-975 | 1.1e-23 | 78.8 | In-house | 195-288 (319) | alignment | ||
Range on Protein: 882-975
Range on HMM: 195-288/319.0
REPHTILQVIDDVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFKLHST
.. ..|... .. . ..| ||.|||||. | | | .. ....||. | |||.|||.. . .| .. | . |||. ||... . . .|
ekatslldllkrirksrektqsgPivvhCsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyealleaveagdt
|
|||||||||
subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 879-977 | 6.6e-23 | 76.3 | In-house | 189-287 (318) | alignment | ||
Range on Protein: 879-977
Range on HMM: 189-287/318.0
GIVREPHTILQVIDDVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFKLHSTYA
|. .. ..|... .| . ||| | ||.||||| | | ||.. |.| ||. |||..|||||. | .|. .. | | .||. ||||. . . |..
gvpesgaslldlvrqvskaqqksgagpivvhCsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqtedqyefiydvllealasgdtev
|
|||||||||
subfamily_PTPRA_pd | Subfamily PTPRA | 879-971 | 2.5e-21 | 70.9 | In-house | 205-296 (330) | alignment | ||
Range on Protein: 879-971
Range on HMM: 205-296/330.0
GIVREPHTILQVIDDVIHRQQKIGGgPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFK
|. || .|... | . .|. .| |.||||| | |.| .. .. ||. |||..||||.. | .| .| | |.|||. || |. |.
GvPfepiGmlkllkkvkklnqqsag.pivvhcsaGvGrtGtfivldavlervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvlleyyl
|
|||||||||
0037934 | (Phosphotyrosine protein) phosphatases II | 825-970 | 3.6e-21 | 71.3 | In-house | 1-242 (243) | alignment | ||
Range on Protein: 825-970
Range on HMM: 1-242/243.0
PCTIGYSEENKPFNRFKNITVYDDNRIILatnpnlDMcqREYINASYVDGYS----------------------------SNGIV---------------
...|. ..||.. ||...| ||..|..| . ||||...... .. ||
sfsiallpenlsknrysdilpydhsrvkl......eg..sdyinanliyvtprliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaq
---------------------------------------------------------REPHTILQVIDDVIHRQQK-------IGGGPVVVHCSDTVSRS
.| .|. .|.|. ... .||||.|||| |.|.
ywpgevtygdftvtllseehlddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRt
GVYCSVSIALEQCkaeGvVDVFQVTKAIRRSKPG-AVTTLEQYTSIYDVIDMYF
|... . |... | ||.... | .|. .|| ||.|..|| .|... ...
Gtliaaylmllll...g.vdleeavkllreqRpgkavqtpsqyrflyeallell
|
|||||||||
DSPc_SM00195 | 879-971 | 5.5e-21 | 70.4 | In-house | 172-263 (263) | alignment | |||
Range on Protein: 879-971
Range on HMM: 172-263/263.0
GIVREPHTILQVIDDVIHRQQKIgGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFK
|. ... .|... | ...... ||.|||||. |.|.|......|.|.....| ||.|.. |..| ..||.|.|||||. ||..| |.|
gvpdstksvlellravkksksts.sgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyik
|
|||||||||
PTPc_SM00194 | 879-971 | 5.5e-21 | 70.4 | In-house | 172-263 (263) | alignment | |||
Range on Protein: 879-971
Range on HMM: 172-263/263.0
GIVREPHTILQVIDDVIHRQQKIgGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFK
|. ... .|... | ...... ||.|||||. |.|.|......|.|.....| ||.|.. |..| ..||.|.|||||. ||..| |.|
gvpdstksvlellravkksksts.sgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyik
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 882-966 | 6.1e-21 | 70.3 | Pfam-A | 150-233 (235) | alignment | ||
Range on Protein: 882-966
Range on HMM: 150-233/235.0
REPHTILQVIDDVIHRQqKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVI
..|. .|..|..| ... . ||||||||. |.|.|......|.|||..||. |||.|. | .|...||.|..|||| .|..|
espkslldlirkveksk.eaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmvqsleqYiflykai
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 882-966 | 6.1e-21 | 70.3 | In-house | 150-233 (235) | alignment | ||
Range on Protein: 882-966
Range on HMM: 150-233/235.0
REPHTILQVIDDVIHRQqKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVI
..|. .|..|..| ... . ||||||||. |.|.|......|.|||..||. |||.|. | .|...||.|..|||| .|..|
espkslldlirkveksk.eaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmvqsleqYiflykai
|
|||||||||
subfamily_CG7180_pd | Subfamily CG7180 | 901-969 | 1e-20 | 68.6 | In-house | 221-289 (296) | alignment | ||
Range on Protein: 901-969
Range on HMM: 221-289/296.0
IGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMY
|||||..|| .||||||... ..||. . |. ||||. | .|||.|. | . |.| ||||. .
peegPvvvvssdGasRsGvylaidanlelvekeeevdvFeavktlrrsRpqLvenveeYkyiYdvllea
|
|||||||||
PTPc_DSPc_SM00012 | 874-966 | 1.1e-20 | 69.2 | In-house | 9-103 (105) | alignment | |||
Range on Protein: 874-966
Range on HMM: 9-103/105.0
GYSSNGIVREPHTILQVIDDVIHRQQKIG-GGPVVVHCSDTVSRSGVYCSVSIALEQCKAE-GVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVI
|.. |. .|.. ||.....| . ..|.. ..|||||||. |.|.|... ..|.|.|...| . ||.||. |..|...||.|.|.||| .|...
gwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylflyral
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 817-965 | 1.8e-20 | 67.7 | In-house | 30-189 (440) | alignment | ||
Range on Protein: 817-965
Range on HMM: 30-189/440.0
SLKSGEEKPCTIGYSEENKPFNRFKNITVYDDNRIILATNPnlDMCQREYINASYVD-------------GYSSNGIVREPHTILQVIDDVIHRQQKIGG
| || .|. | .|| ||..|| .|| .|..| . . .||||||.. |. .|. . .|..|.|| . |.| |
llpsglsqpsdiaslpnnkvknryrnilaydhsrvmleevk..gvpdsdyinasyingiesrtlkqyhyqgwpdkgvpkfagpvlkmiqdvnesqekagn
GPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDV
||..|||| ..|.|| .| | ..| .|.| . ...| ..| | | |||. ....
gpllvhcsagagrtgviiavdsilreakrsdqidifsfinsmrnnrpqmvqtpeqyafvhea
|
|||||||||
subfamily_PTPRK_pd | Subfamily PTPRK | 885-966 | 1e-19 | 65.5 | In-house | 193-273 (314) | alignment | ||
Range on Protein: 885-966
Range on HMM: 193-273/314.0
HTILQVIDDVIHRQQKiGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVI
...|... | . |.. . |..||||| |.|... ..| |. . |||||||.. |..| .|. | | |||. |||||
tgllklvrrvkksqee.eaGrivvhCsaGaGrtGtfiaidivldmieregvvdvfnavktlrsrkvnmveteeqykfiydvi
|
|||||||||
subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 891-966 | 2.1e-18 | 61.2 | In-house | 187-262 (283) | alignment | ||
Range on Protein: 891-966
Range on HMM: 187-262/283.0
IDDVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVI
.. || |.. ||.||||| .. |..|....| .... ..| |||||.| | .| ...|| ||.|| .....
fnkvislqteskkgPivvhCstgiGrtavfiaasasvkdaltesvvdvfavvkimreqrmmavqtldqyklvhelv
|
|||||||||
subfamily_Ptp69D_pd | Subfamily Ptp69D | 883-969 | 6.1e-18 | 60.0 | In-house | 200-285 (307) | alignment | ||
Range on Protein: 883-969
Range on HMM: 200-285/307.0
EPHTILQVIDDVIHRQQKIgGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMY
....|..|. | . ... .|.||||| |.|||.. .... |.|.||| ||.|...| .|. .. |. ||||. .| . |
vargllklieqvrelykln.rsPivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnllvqsleqYvflyralldy
|
|||||||||
subfamily_PTPRG_pd | Subfamily PTPRG | 899-966 | 6.9e-17 | 55.9 | In-house | 216-283 (563) | alignment | ||
Range on Protein: 899-966
Range on HMM: 216-283/563.0
QKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVI
.| ||.||||| |.|.|.|. .. |.| ..| .|.||.. | || .. |.| |||. ..|..
nkaeaGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvqteEqYiflhdal
|
|||||||||
subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 882-971 | 8.4e-17 | 56.1 | In-house | 178-269 (274) | alignment | ||
Range on Protein: 882-971
Range on HMM: 178-269/274.0
REPHTILQVIDDVIHRQQKI--GGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFK
....|.|.....| . ... .||||||| . | |.. ..|||. | ..|.||||.... .| . | | | ||| |. .. .| |
ddantlldlvleveesreeenaklapvvvhCsaGiGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralclylk
|
|||||||||
subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 889-967 | 1.1e-16 | 55.7 | In-house | 199-276 (315) | alignment | ||
Range on Protein: 889-967
Range on HMM: 199-276/315.0
QVIDDVI-HRQQKIggGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVID
..| | |..... |..|||||. | |.| ..... |.| .|| ..||... . .|. . ..| ..||| |||..
nlirtvkqhhtnsv..gaivvhcsaGvGrtGtfitldavldqaeaenaidvynfitgvrqnrikmvqvaeqyqfiydall
|
|||||||||
subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 885-970 | 2.8e-16 | 54.5 | In-house | 199-284 (297) | alignment | ||
Range on Protein: 885-970
Range on HMM: 199-284/297.0
HTILQVIDDVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYF
...|..|..| . .. ||..|||. | | ||.... . . | | ||.|.. | .|...| | | |||. .| .. ..
ssllklisevrkdfsqnaegPllvhclaGvGrtgvlltidsvvaeakrekevdifglvkklrqerpylvqtkeqykfvyvavleal
|
|||||||||
subfamily_PTPN6_pd | Subfamily PTPN6 | 878-974 | 6.8e-16 | 53.1 | In-house | 199-301 (306) | alignment | ||
Range on Protein: 878-974
Range on HMM: 199-301/306.0
NGIVREPHTILQVIDDVIHRQQKIG---GGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGV---VDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFK
.|. ..| ..|. ..|| ..|... ||.|||||. . | | . . | |.. . .|. .|. .. | .|. . | | | .|| .| .| .| .
hgvpkdpgavLdfledvnrkqeeleeaeagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqteqqykfvykaikkyie
LHS
..
tkk
|
|||||||||
0041856 | (Phosphotyrosine protein) phosphatases II | 834-971 | 9.5e-16 | 53.4 | In-house | 1-172 (182) | alignment | ||
Range on Protein: 834-971
Range on HMM: 1-172/182.0
NKPFNRFKNITVYDDNRiilatnpnldmcQREYINASYVDGYSSN-------------------------------------------------------
|.. ||...| || .| ||||....|. .
nldknrysdilpydhsr............dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlteelywpellerlgiqylylpwp
--GIVRePHTILQVIDDVIHrqqkiGGGPVVVHCSDTVSRSGVYCSVSIALEQckaeGvVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFK
|. ....|. |..|.. ||||.|||| |.|.|... . ... | |..... | .|. .||.|.|..|| ..... ....
Dhgvpd.ldelldfieevle.....eggpvlVHCsaGvgRtgtlvaaylmkkl....g.vsleeavklvrsrRpgmvitpnqyfflqlallelll
|
|||||||||
subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 878-974 | 1e-15 | 52.4 | In-house | 186-281 (315) | alignment | ||
Range on Protein: 878-974
Range on HMM: 186-281/315.0
NGIVREPHTILQVIDDVIHRqQKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFKLHS
.|. .. ..|..| .| .. ...|||| | |.|| .|. ..| | . .||||.. | .|. .| | | |.|. |||.. ... .
kGvdkqtssllklikevkad.ngkkefsllvhcsaGvGrtGvvisidevvaqikrtrsvdvfnfvknlrakrpylvqteeeyafiydavledllwrn
|
|||||||||
subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 878-972 | 1.1e-15 | 51.8 | In-house | 185-278 (515) | alignment | ||
Range on Protein: 878-972
Range on HMM: 185-278/515.0
NGIVREPHTILQVIDDVIHRQQKIGgGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFKL
.|. .. ..|..| .| .... |...||| | | ||..|. . . | .||||.. . ||. .| | | |||. ||... ...
kGvpkhtssllklikevkadhgqyt.hpliihcsaGvGrtGvvisidsvvahakttrmvdvfnfvtnirqkrpylvqtqeqyafiygavledllw
|
|||||||||
0049772 | (Phosphotyrosine protein) phosphatases II | 813-971 | 1.4e-15 | 53.3 | In-house | 25-281 (314) | alignment | ||
Range on Protein: 813-971
Range on HMM: 25-281/314.0
LNTHSLKSGEEKPCTIGYSEENKPFNRFKNITVYDdNRIILatnPNLDMCQREYINASYVDGYsSNGIVREPHT--------------------------
||..|| |. ..... ..|. ||...| .| || || |.|.. |||||||||. . |. . ..
lnrrslsvlpeltilvadlflnrdknryldilpad.nrvil...pglpvsgsdyinasyvdgf.lkfIatqgpleitvvdfreepvlyyngwrmvlrgdl
---------------------------------------------------------------------------ILQVIDDV---IHRQqkIGGGPVVV
.|. .|.. |.. ||||.|
nvrdivmsrdevladelsrLdaAlgKtpllildgngneptaadlellkeelydpelferlgikylripvpDgsaplledfdeflefieea..dkggpvlv
HCSDTVSRSGVYCSVSIALEQCkaeGVvDVFQVTKAIRRSKP-----GAVTTLEQYTSIYDVIDMYFK
||.. ..|.|... . . . .. || .. .. . .|. | |.. .|||| |.... .|.|
HCkaGkgRtgtfvvaaylmkll...gv.sleealedvrlkRpinpnpgfieqleqyefilealleylk
|
|||||||||
subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 818-877 | 3.8e-15 | 50.5 | In-house | 29-89 (290) | alignment | ||
Range on Protein: 818-877
Range on HMM: 29-89/290.0
LKSGE-EKPCTIGYSEENKPFNRFKNITVYDDNRIILATNPNLDMCQREYINASYVDGYSS
|.||| |. |.| ...||. |||.|| |||||||.| .. |. |||||.|..||.
ldsgesehtvtvgltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgyke
|
|||||||||
subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 885-969 | 4e-15 | 50.8 | In-house | 198-287 (325) | alignment | ||
Range on Protein: 885-969
Range on HMM: 198-287/325.0
HT---ILQVIDDVIHRQQK--IGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMY
| |||... | | . . .|..||||. | |.||. |. ||.. | ||.|.. | .|. .| | | .||. ||. . .
atlisilqlvkavservtantkastpilvhcsaGvGrtGvfislysalakvieesrvdifgfvkklrkdrpsmvetvdqyiliyealvea
|
|||||||||
0051429 | (Phosphotyrosine protein) phosphatases II | 865-971 | 6.7e-15 | 51.0 | In-house | 5-226 (272) | alignment | ||
Range on Protein: 865-971
Range on HMM: 5-226/272.0
EYINASYVDGYssNGIVREP--------------------------------------------------------------------------------
||||..|.|| .. |..
gyiNardvggy..grvvkpgrlyrsggplpltaadfwrlkelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseellld
-----------------------------------HTILQVIDDVIHrqqkigGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVD--------VFQV
...|.... . . ||||.|||| ..|.|... . . |.. .| .|| ....
yilrellltlllsagearevmhlhytdwpdhgvpqeallellellld......ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlyleea
TKAIRRSKPGAVTTLEQYTSIYDVIDMYFK
. .|. |||| | ||| .|... ...
veelraqrpgavqteeqylflyeallellr
|
|||||||||
subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 896-966 | 1e-14 | 49.2 | In-house | 185-255 (267) | alignment | ||
Range on Protein: 896-966
Range on HMM: 185-255/267.0
HRQQKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVI
. | . |. |.||.||| | ||| . . ||. | |||.|.|. . || ..| | |.|.| |....
knqlengnrPlvvacsdGvGrsGtflvidsqleraktegvsdifdflrkirsqriglvdtkeryiyihell
|
|||||||||
0036282 | (Phosphotyrosine protein) phosphatases II | 885-964 | 2.2e-14 | 49.0 | In-house | 87-164 (174) | alignment | ||
Range on Protein: 885-964
Range on HMM: 87-164/174.0
HtILQVIDDVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKaEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYD
.|.... | . ... .||||.|||| |.|.|. . . | . . |..||.... ...|. .||.|.| .|| .|.
i.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtpsQyrflyy
|
|||||||||
subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 881-972 | 2.7e-14 | 47.8 | In-house | 174-266 (270) | alignment | ||
Range on Protein: 881-972
Range on HMM: 174-266/270.0
VREPHTILQVIDDV-IHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFKL
. ... .|... .| ..... ..|..||||. | |.|. . ||.. . .. ||| .. ...|. .. | . |||. .| .. .| .
slstdqllkmlravrrsekeldkaePllvHcsaGvgRtGtlialDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyeflykavveyaer
|
|||||||||
subfamily_PTPN12_pd | Subfamily PTPN12 | 882-972 | 4.2e-14 | 47.1 | In-house | 187-279 (290) | alignment | ||
Range on Protein: 882-972
Range on HMM: 187-279/290.0
REPHTILQVIDDVIHRQQkIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGV---VDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFKL
. ....|..|..| ..|. |.||||| | | |. ... .. |. ||| . .|||.. .|. .. .| | |||. .| . ...
ssaksllelielvrelqe.sedaPlvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelvqk
|
|||||||||
subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 886-966 | 7.8e-14 | 46.4 | In-house | 196-275 (288) | alignment | ||
Range on Protein: 886-966
Range on HMM: 196-275/288.0
TILQVIDDVIHrQQKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVI
.|.... | ... ||..||||. | |.|.. .. .... ..| ..||. . . .|.... | ||.|| ||.|.
pllellrqvkv.anqadtgpiivhCsaGvGrtgtFialdalidaveeedyiDvagtvaklRkqRallvqtlkqYefiyevl
|
|||||||||
subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 881-965 | 1.8e-13 | 45.5 | In-house | 201-286 (319) | alignment | ||
Range on Protein: 881-965
Range on HMM: 201-286/319.0
VREPHTILQVIDDVIHRQQKIGG-GPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDV
| ...... | | ..| . ..||||| | |.||| . . |.. | | |||... . .|. .. | | || ||
pdypsdlmrlvkkvrhltskenhranivvhcsaGvGrtGvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysa
|
|||||||||
subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 817-877 | 2.1e-13 | 45.1 | In-house | 30-87 (305) | alignment | ||
Range on Protein: 817-877
Range on HMM: 30-87/305.0
SLKSGeEKPCTIGYSEENKPFNRFKNITVYDDNRIILATNPNLDmcQREYINASYVDGYSS
|| . |... .| .|.|| ||.|.||..||.||||.....|| ...||||||||||..
slyee.eesidvgkkeankaknrlkeitlldddriiltekesld..dsdyinasyvdgykr
|
|||||||||
subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 879-966 | 2.1e-13 | 45.4 | In-house | 163-251 (284) | alignment | ||
Range on Protein: 879-966
Range on HMM: 163-251/284.0
GIVREPHTILQVIDDVIHRQQKIGG-GPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVI
| | ...... | | ..| . ..||||| | |.||| . . |.. | | |||... . .|. .. | | || || .
gvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrtgvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysal
|
|||||||||
subfamily_PTPRB_pd | Subfamily PTPRB | 879-969 | 2.4e-13 | 44.8 | In-house | 193-284 (293) | alignment | ||
Range on Protein: 879-969
Range on HMM: 193-284/293.0
GIVREPHTILQVIDDVIHRQ-QKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMY
|. ...|.|. . | ... .. .|.||||| | |.|.. .. |.. . | .||.| . ..|... | | .|| |.... .
gvPektktlldfvrtvreaiektaskrPivvhCsaGvGRtGtfialdrllqaieeedyvdifgivaelReeRnllvqtekqYifihqcvldl
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 902-971 | 4.7e-13 | 43.5 | In-house | 246-316 (319) | alignment | ||
Range on Protein: 902-971
Range on HMM: 246-316/319.0
GGGPVVVHCSDTVSRSGVYCSVSIALEQCKAE-GVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFK
||.|||||| | |.|. . ||... . ||. |. .|| . || | ||| || |. .| |
sqGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefiykvlseyak
|
|||||||||
fn3 | Fibronectin type III domain | 408-494 | 2.8e-12 | 39.8 | Pfam-A | 1-82 (85) | alignment | ||
Range on Protein: 408-494
Range on HMM: 1-82/85.0
SPVTSLSVSNVSTTGITVSWNIP-SSDNYVTYYTIFYTPSCPQLssVNETVSVGPHqsttTYSYTLAGLYSGMNYTITVRAGNVLGGS
|... ||||.|..| .|.||. | . . .|.|.. | .. . . ...| .. |.|.|| || |..|...|.| | |..
saPenlsvsevtstsltlsWsppkdgggpitgYeveyrekggge..ewkeftvprt....ttsvtltgLkpgteYefrVqavngageg
|
|||||||||
subfamily_PTPN9_pd | Subfamily PTPN9 | 898-966 | 3.2e-12 | 41.1 | In-house | 218-286 (297) | alignment | ||
Range on Protein: 898-966
Range on HMM: 218-286/297.0
QQKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVI
. .. | |.||||| . |.| .... |.|.. . .|.|||... | .| . .. | |||. | .
kghpsgPPivvhcsaGiGrtGtfitldiclsrleevgtvdvvetvkllrtqrafsiqtpeqyefcylav
|
|||||||||
0043147 | (Phosphotyrosine protein) phosphatases II | 879-964 | 5.3e-12 | 41.3 | In-house | 76-155 (172) | alignment | ||
Range on Protein: 879-964
Range on HMM: 76-155/172.0
GIVREPHTILQVIDDVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIALeqckaeG-VvDVFQVTKAIRRSKPGAVTTLEQYTSIYD
. | . .|.... . ..... ||||.|||| |.|.|. . . | . ..... . .|. .||||.. .|| .|.
hgvpllellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml......lgl.sleeavalvrekRpgavqnpsqyrflyy
|
|||||||||
subfamily_PTPRD_pd | Subfamily PTPRD | 817-877 | 6.1e-12 | 39.9 | In-house | 31-89 (564) | alignment | ||
Range on Protein: 817-877
Range on HMM: 31-89/564.0
SLKSGEEKPCTIGYSEENKPFNRFKNITVYDDNRIILATNPNLdmCQREYINASYVDGYSS
....|.. ... ..||. ||..||. || .|..| . .. . .|||||..||| .
kieegqqftweaankpaNkaKNRyanivaYdhsRVvLskvegd..egsDYINAsfidgyrk
|
|||||||||
subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 823-878 | 8e-12 | 39.7 | In-house | 36-85 (287) | alignment | ||
Range on Protein: 823-878
Range on HMM: 36-85/287.0
EKPCTIGYSEENKPFNRFKNITVYDDNRIILAtnpnldMCQREYINASYVDGYSSN
|. |.. ...||. ||...| |.|..|..| .. .||||...|||...
edevthniasqnkdknRltqilvpdnyrvllk......gehpdyinavfidgykek
|
|||||||||
0046846 | (Phosphotyrosine protein) phosphatases II | 886-970 | 1e-11 | 40.4 | In-house | 94-173 (176) | alignment | ||
Range on Protein: 886-970
Range on HMM: 94-173/176.0
TILQVIDDVIHRQQKigGGPVVVHCSDTVSRSGVYCSVSialeQCKAEGVVDVFQVTKAIRRSKP-GAVTTLEQYTSIYDVIDMYF
.|.... . .... ||||.|||| ..|.|... .. | ..|... . .|. .| |||.| ||| .|... ...
lllellefirealke..ggpvlVHCsaGigRtgtlvaay....llelekglsveealalvreqRplgavqtpeQyrflyefellll
|
|||||||||
0049260 | (Phosphotyrosine protein) phosphatases II | 881-964 | 1.1e-11 | 40.1 | In-house | 67-144 (152) | alignment | ||
Range on Protein: 881-964
Range on HMM: 67-144/152.0
VREPHTILQVIDDVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIALeqckaeGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYD
| . . .|. . ..|.. .. ||||.|||| |.|.|... . | |..... . .|. .||||.. .|. .|.
vpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpgqlrflye
|
|||||||||
fn3 | Fibronectin type III domain | 137-211 | 1.3e-11 | 37.7 | Pfam-A | 2-79 (85) | alignment | ||
Range on Protein: 137-211
Range on HMM: 2-79/85.0
APSSLTEVSKTATTITVSWTALD--SSDADGYVVNVTSDTDT--VQTVQVEGSSNdTIVLNGLRELTTYSIIVRAYQQL
||. |. . |.|..|.||.. . ... .|| | . ..... ....|..... . .|.||.. |.|.. |.|. .
aPenlsvsevtstsltlsWsppkdgggpitgYeveyrekgggeewkeftvprttt.svtltgLkpgteYefrVqavnga
|
|||||||||
subfamily_PTPN13_pd | Subfamily PTPN13 | 879-966 | 1.5e-11 | 39.1 | In-house | 180-265 (273) | alignment | ||
Range on Protein: 879-966
Range on HMM: 180-265/273.0
GIVREPHTILQVIDDVIHRQQkiGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVI
|. ... .||.. | . |. ||.||||| . |||.. .. ..|. . . .|| .. . .|. . | | | .|| .| .|
gvPssaaellqfvaevrrlqt..dagPivvhcsaGiGrsGtlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykai
|
|||||||||
subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 895-963 | 2e-11 | 38.5 | In-house | 165-233 (239) | alignment | ||
Range on Protein: 895-963
Range on HMM: 165-233/239.0
IHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIY
| .. | | |.||| | |.| . . | |.| . ||.|. |||| .| | | ||| |.
itkdslpgarpwvihcsagvgrtgaflvidamlrqakkqktvdifnyvkairedrphmvqtseqyvfih
|
|||||||||
subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 895-963 | 2.1e-11 | 38.5 | In-house | 166-234 (239) | alignment | ||
Range on Protein: 895-963
Range on HMM: 166-234/239.0
IHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIY
| .. | | |.||| | |.| . . | |.| . ||.|. |||| .| | | ||| |.
itkdslpgarpwvihcsagvgrtgaflvidamlrqakkqktvdifnyvkairedrphmvqtseqyvfih
|
|||||||||
subfamily_PTPN23_pd | Subfamily PTPN23 | 877-966 | 2.8e-11 | 37.8 | In-house | 183-276 (288) | alignment | ||
Range on Protein: 877-966
Range on HMM: 183-276/288.0
SNGIVREPHTILQVIDDVIH---RQQKIGGGPVVVHCSDTVSRSGVYCSVSIALEQC-KAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVI
. |. |.|.||..| | . .|. |.||||| | |.||.. | |... | .|..|. || . .|. . | . ||. |...
elGvPasPetllqfldevesayeavqrksktPlvvhCsaGvgRtgvfalvyaavrelekgnglldiiqvvsrlreqRrfmvqekeqlkfsyeav
|
|||||||||
subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 897-966 | 3.7e-11 | 37.1 | In-house | 206-275 (439) | alignment | ||
Range on Protein: 897-966
Range on HMM: 206-275/439.0
RQQKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVI
..| |||||||| | |.| .. ||||| |.| ||. . | .|. . | .| || ||. .
andkeeygpvvvhcsagvGrtGtiialdialeqlklenkvdikgivkvlrkqrkqmvqalcqyvfiynav
|
|||||||||
subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 878-966 | 6.9e-11 | 36.8 | In-house | 146-235 (237) | alignment | ||
Range on Protein: 878-966
Range on HMM: 146-235/237.0
NGIVREPHTILQVIDDVIHRQQKI-GGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVI
.|. .. ..|. ..|.| ... || ..||| | |.|.. . | |.| . |||... ..| .| . | .|| |...|
rgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlrqakekkvvdiynyvysieedrpyiiqtkdqyvfihqti
|
|||||||||
0048076 | (Phosphotyrosine protein) phosphatases II | 882-969 | 9e-11 | 37.1 | In-house | 62-142 (145) | alignment | ||
Range on Protein: 882-969
Range on HMM: 62-142/145.0
REPHTILQVIDDVIHRQQKigGGPVVVHCSDTVSRSGVYCsvsiALEQCKAEGvVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMY
. ..|.... . . ... ||||.|||| |.|.|... |. .. .| |..... . .|. ||||.. .|. .|... ..
dllellleflefieealke..ggpvlVHCsaGvgRtgtlv....aaylmlllg.vsleealelvrsqrpgavpnpgqlrflyefelel
|
|||||||||
0051082 | (Phosphotyrosine protein) phosphatases II | 865-965 | 9.9e-11 | 37.0 | In-house | 59-148 (151) | alignment | ||
Range on Protein: 865-965
Range on HMM: 59-148/151.0
EYINASYVDGYSSNgivrePHTILQVIDDVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIALEQckaegvVDVFQVTKAIRRSKPGAVTTLEQYTSIYD
|... ..| . .... . .... .. ..|||.|||| ..|.|. . . . |.. |..... . .|.. ||.|.. .|. ..
evlhipildwpdpg.....lplsfdavleflellldkkngpvlvHCsaGkgRTGtlvalylmllg......vsleealeeyrlkrpgvvqpnqqflfqlf
V
.
a
|
|||||||||
subfamily_PTPN14_pd | Subfamily PTPN14 | 903-971 | 1.4e-10 | 35.6 | In-house | 229-297 (300) | alignment | ||
Range on Protein: 903-971
Range on HMM: 229-297/300.0
GGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFK
||.||||. | |.|| . . .. . . ..|. .| . .|. . | || ||. .|.|. |.|
kPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLreqrmllvqtlaqYkfvYkvlikylk
|
|||||||||
subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 904-966 | 1.6e-10 | 35.0 | In-house | 170-232 (392) | alignment | ||
Range on Protein: 904-966
Range on HMM: 170-232/392.0
GPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVI
|...||| | |.|| |. . ..| .||||.. ||| .| | | |||. || .
hpliihcsagvgrtgvvisidsvvahakktrmvdvfnfvtnirrkrpymvqtkeqyafiygav
|
|||||||||
subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 879-970 | 2.4e-10 | 35.0 | In-house | 184-276 (281) | alignment | ||
Range on Protein: 879-970
Range on HMM: 184-276/281.0
GIVREPHTILQVIDDVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAE-GVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYF
|. ... .|. ..| . ..| |.|.||| | |.|.| .. ......|| .|| .| . .|... | |. ||. .| .. ..
GvPattkellefrkevlkltekktkaplvihCsaGvGrtGtyialDrlvkaveaeleeldvkavvaelrkernlmvqtvvqyefvykavldal
|
|||||||||
subfamily_Sponge-PTP3_pd | Subfamily Sponge-PTP3 | 819-877 | 3.9e-10 | 33.8 | In-house | 33-86 (95) | alignment | ||
Range on Protein: 819-877
Range on HMM: 33-86/95.0
KSGEEKPCTIGYSEENKPFNRFKNITVYDDNRIILATNPNLDmcqreYINASYVDGYSS
| |.| || | | ||| || || |..|.|. . | |||| .||||.
smtsgapytvgsseanipknrflnifpydatrvvlttkrdsd.....yinacfvdgyar
|
|||||||||
0044763 | (Phosphotyrosine protein) phosphatases II | 885-972 | 7.4e-10 | 34.2 | In-house | 92-173 (178) | alignment | ||
Range on Protein: 885-972
Range on HMM: 92-173/178.0
HTILQVIDDVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIALEQckaeGVvDVFQVTKAIRRSKPgAVTTLEQYTSIYDVIDMYFKL
... . . |.. .. ||||.|||| |.|||. . . ... |. ..... . .|. .| .|.. .|. .|.. ...|
lehflefvefieealdekggpvlVHCsaGvgRsgtlvaaylmkkl....gl.sleeaielvrerRp.ivpnpgqlrqLyefelrllke
|
|||||||||
0048179 | (Phosphotyrosine protein) phosphatases II | 883-964 | 7.5e-10 | 34.2 | In-house | 65-139 (144) | alignment | ||
Range on Protein: 883-964
Range on HMM: 65-139/144.0
EPHTILQVIDDVIHRQQkiGGGPVVVHCSDTVSRSGVYCSVSIALeqckAEGvVDVFQVTKAIRRSKPGAVTTLEQYTSIYD
.. .|.... . . .. ||||.|||| |.|.|... . . .| ...... . .|. ||||.. .|. ...
llellleflefieeale..eggpvlVHCsaGvgRtgtlvaaylmk....klg.lsleealalvrsrrpgavpnpgqlrfLle
|
|||||||||
subfamily_PTPN3_pd | Subfamily PTPN3 | 878-966 | 7.8e-10 | 33.1 | In-house | 184-271 (280) | alignment | ||
Range on Protein: 878-966
Range on HMM: 184-271/280.0
NGIVREPHTILQVIDDViHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVI
.|. ... .|.... | ..... ||||||| . |.||. . .|| |. | . .. . .| . | | .||. . . |
hgvPddsadflefverv.rklrsgkeePvvvhCsaGigrtGvlilletalalieaaepvypldivrtmrdqramlvqtasqykfvCeai
|
|||||||||
subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 903-965 | 2.2e-09 | 31.8 | In-house | 135-199 (199) | alignment | ||
Range on Protein: 903-965
Range on HMM: 135-199/199.0
GGPVVVHCSDTVSRSGVYCSVSIALE---QCKaEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDV
||.||||| .||. .. | . . | |||.|.|.| .|... | ...|..| ||.|
dapvivhcsdgqgftgvfvaldigvrsheesk.tsvvdlfevakrlrqarcgiisslqhynfiyqv
|
|||||||||
subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 903-965 | 2.2e-09 | 31.8 | In-house | 134-198 (198) | alignment | ||
Range on Protein: 903-965
Range on HMM: 134-198/198.0
GGPVVVHCSDTVSRSGVYCSVSIALE---QCKaEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDV
||.||||| .||. .. | . . | |||.|.|.| .|... | ...|..| ||.|
dapvivhcsdgqgftgvfvaldigvrsheesk.tsvvdlfevakrlrqarcgiisslqhynfiyqv
|
|||||||||
subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 823-877 | 2.3e-09 | 31.7 | In-house | 37-89 (319) | alignment | ||
Range on Protein: 823-877
Range on HMM: 37-89/319.0
EKPCTIGYSEENKPFNRFKNITVYDDNRIILATNPNldMCQREYINASYVDGYSS
.. . ||||. ||..|| || |..|.. .. . . .|||||..|||
ndtfdsaskeenkkknryqnilaydrtrvvlseldg..vegsdyinasfidgyqe
|
|||||||||
DSPc_SM00195 | 817-877 | 3.5e-09 | 31.7 | In-house | 9-67 (263) | alignment | |||
Range on Protein: 817-877
Range on HMM: 9-67/263.0
SLKSGEEKPCTIGYSEENKPFNRFKNITVYDDNRIILATNPNLdmCQREYINASYVDGYSS
...| ..|..| . ..|| ||.||| .||..|..| .... . .||||.|..|...
leestspketteaekkknksknRyknilpydhtrVklkkeekk..egsdYINAnyikgank
|
|||||||||
PTPc_SM00194 | 817-877 | 3.5e-09 | 31.7 | In-house | 9-67 (263) | alignment | |||
Range on Protein: 817-877
Range on HMM: 9-67/263.0
SLKSGEEKPCTIGYSEENKPFNRFKNITVYDDNRIILATNPNLdmCQREYINASYVDGYSS
...| ..|..| . ..|| ||.||| .||..|..| .... . .||||.|..|...
leestspketteaekkknksknRyknilpydhtrVklkkeekk..egsdYINAnyikgank
|
|||||||||
subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 819-877 | 3.7e-09 | 31.1 | In-house | 25-82 (281) | alignment | ||
Range on Protein: 819-877
Range on HMM: 25-82/281.0
KS-GEEKPCTIGYSEENKPFNRFKNITVYDDNRIILATNPNLDmcQREYINASYVDGYSS
.. | ... | ...||. ||..||. || |. .. | . . .||||..|.||..
aaigvdntataskadenvlknrYsnivaYDatrvkvtpneenk..ntDYinanfvpgykg
|
|||||||||
subfamily_PTPRG_pd | Subfamily PTPRG | 823-877 | 3.8e-09 | 30.3 | In-house | 36-89 (563) | alignment | ||
Range on Protein: 823-877
Range on HMM: 36-89/563.0
EKPCTIGYSEENKPFNRFKNITVYDDNRIILATNPNLDMCQrEYINASYVDGYSS
. ... .||| || ||. || |. |. |. . .||||.|.|||
dldaehsqkpenkrKnRylnivaydrsRvklsplpgkkkkl.DYinAnyidGyqk
|
|||||||||
subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 868-971 | 9.7e-09 | 29.8 | In-house | 161-260 (290) | alignment | ||
Range on Protein: 868-971
Range on HMM: 161-260/290.0
NASYVDGYSSNGIVREPHTILQVIDDVIhrQQkigGGPVVVHCSDTVSRSGVYCSVSIALEQCK-AEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVI
. | . |... . ... |.|..|. | .. . ||.||| | .||| . .. .. .| | . .| ||.|. . |.|. .... . .|
tHsllkgWnklnvqedtktllsliqkvk..as...ktpvivHcvdGiSrsAalaaiilgyQkiaetsgsvkledvlkalrkqralaitsalelafvdagi
DMYFK
....
vllai
|
|||||||||
subfamily_Ptp69D_pd | Subfamily Ptp69D | 823-876 | 1.1e-08 | 29.5 | In-house | 37-88 (307) | alignment | ||
Range on Protein: 823-876
Range on HMM: 37-88/307.0
EKPCTIGYSEENKPFNRFKNITVYDDNRIILATNPNLDmcQREYINASYVDGYS
.| .... .||. ||...|. .|..|..|.. . . . .|||||.. ||
dkstkvsekkenalknRyedikafDktRvkLkkingke..dsdYinasfikgyk
|
|||||||||
fn3 | Fibronectin type III domain | 606-697 | 1.5e-08 | 27.9 | Pfam-A | 8-84 (85) | alignment | ||
Range on Protein: 606-697
Range on HMM: 8-84/85.0
VSSImDTTWAVISWSVPSyiPSDYPIITYEIGYHMLQSGNcsmvydddinlqVFNLSNVSSNDTFTIITRLNSNTCYIFGIRAYSDNGYGAW
||.. .| ...||| |. . . || ||. | . ..|. . . .|... | ..| |. .| | | ..|....|.| .
vsev.tstsltlsWsppk..dgggpitgYeveyrekggge............ewkeftvprtttsvtltgLkpgteYefrVqavngagegpe
|
|||||||||
subfamily_PTPN6_pd | Subfamily PTPN6 | 827-875 | 2.8e-08 | 28.1 | In-house | 47-92 (306) | alignment | ||
Range on Protein: 827-875
Range on HMM: 47-92/306.0
TIGYSEENKPFNRFKNITVYDDNRIILAtnpNLDMCQREYINASYVDGY
. | ||| ||.||| .|..|.||. . .. . .||||.|...
kegakpenkeknryknilPfDhtrvilk...epsvpgsdyinanyikke
|
|||||||||
subfamily_PTPRB_pd | Subfamily PTPRB | 821-878 | 3.8e-08 | 27.7 | In-house | 38-93 (293) | alignment | ||
Range on Protein: 821-878
Range on HMM: 38-93/293.0
GEEKPCTIGYSEENKPFNRFKNITVYDDNRIILATNPnlDMCQREYINASYVDGYSSN
|... ... ...|. ||..|| || .|. ||. | . .||||.|..||.|.
gkdqavkaaelavnraknrytnilpydhsrvkLaalk..desgsDYinanyipgynsp
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 905-966 | 4e-08 | 27.5 | In-house | 230-291 (297) | alignment | ||
Range on Protein: 905-966
Range on HMM: 230-291/297.0
PVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVI
...|||| | |||| . |.. . . . || . . .| .. | ||||.. .||..
yllvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqtleqfellydav
|
|||||||||
subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 893-973 | 4.6e-08 | 27.2 | In-house | 200-280 (287) | alignment | ||
Range on Protein: 893-973
Range on HMM: 200-280/287.0
DVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFKLH
. ... . ||.|||.. . |||.. .. . ... . | ||| .| .| . . | . |. .|. . |.|
hielardasevGPlvvhddvGiGrsGillatlvlvsrledlGrvdvaavvirlreyraalvqavvqlrllyealvtyyktn
|
|||||||||
subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 831-962 | 5.3e-08 | 26.7 | In-house | 158-280 (302) | alignment | ||
Range on Protein: 831-962
Range on HMM: 158-280/302.0
SEENKPFNRFKNITVYDdnriILATNPNLDMCQREYINASYVDGYSSNGIVREPHTILQVIDDVIHRQQKigggpVVVHCSDTVSRSGVYCSVSIALEQC
.. . | |....| . .| . . .. .. . .. | .|..| |... ... |.|||| | |.| .. .. |
ktdleeftdkksfklyt....veiknekkkkkvkktvdilafsawpdhGapkeaytaldilkfcesykkn.....vlvhcsaGvGrtGtlvaikyGiqlc
KAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSI
. . | |. .. . .|. . ||| . .| . .
skkkvtdllsivlpvrqcryGavqdeqqliyl
|
|||||||||
subfamily_PTPN1_pd | Subfamily PTPN1 | 884-963 | 9.6e-08 | 26.1 | In-house | 181-264 (290) | alignment | ||
Range on Protein: 884-963
Range on HMM: 181-264/290.0
PHTILQVIDDVIHRQ-QKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGV---VDVFQVTKAIRRSKPGAVTTLEQYTSIY
| . |. . .| . . ||.|.||| . ||| .| | | . .... ||. .| ..|. . | . | .| |
paaflkflfkvresGslssdvGpavihcsaGiGrsGtfclvdtclvliekkddlssvdikkvllelrkyrlGliqtadqlrfsy
|
|||||||||
subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 902-975 | 1e-07 | 25.7 | In-house | 217-290 (302) | alignment | ||
Range on Protein: 902-975
Range on HMM: 217-290/302.0
GGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFKLHST
. ..|. . | |. .. .|.|. ... . . .. |.|| .| || .|.||.|.| .. .|.| . |
adentvivSknGaGRagafltlavaveklqkgkepnikeivksiRsqRpravdslkQyvslyialllyikkkvt
|
|||||||||
subfamily_Sponge-PTP-7_pd | Subfamily Sponge-PTP-7 | 907-968 | 1e-07 | 26.2 | In-house | 2-63 (69) | alignment | ||
Range on Protein: 907-968
Range on HMM: 2-63/69.0
VVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDM
||||| |.| . .. . . . |.| .||.| . .|. .| | .| |.| .
vvhcssgtgrtgtfiaimvemarikseklvdifnnvqymrkcrpmmvmneieyifihdalve
|
|||||||||
fn3 | Fibronectin type III domain | 525-589 | 1.1e-07 | 25.0 | Pfam-A | 18-85 (85) | alignment | ||
Range on Protein: 525-589
Range on HMM: 18-85/85.0
LTWNEVNcsKHNGLITGYTVVISNS-----SITYTLTSTERYIILKVLAFGTEYNISVAAENSAGIGPFS
|.|.. . . .| ||||.| ... . ..|...|.. .|. | ||||...|.| | || ||.|
lsWsppk..dgggpitgYeveyrekgggeewkeftvprtttsvtltgLkpgteYefrVqavngagegpeS
|
|||||||||
subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 825-877 | 1.1e-07 | 26.2 | In-house | 24-70 (267) | alignment | ||
Range on Protein: 825-877
Range on HMM: 24-70/267.0
PCTIGYSEENKPFNRFKNITVYDDNRIILATNPNLdmcqreYINASYVDGYSS
.. ..|.|. .||. . |||.|.|| |. . |||||||.||
tisqsiaeknqernrlddnlpyddtrvilrtkeee......yinasyvegykt
|
|||||||||
subfamily_PTPRN_pd | Subfamily PTPRN | 903-964 | 1.1e-07 | 25.9 | In-house | 224-286 (297) | alignment | ||
Range on Protein: 903-964
Range on HMM: 224-286/297.0
GGPVVVHCSDTVSRSGVYCSVSIALEQC-KAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYD
|.|||||| . |.|||. . . |.. | .|. . .| .|| | | .|. ..
scpivvhcsdGaGrtGvyilidlvlnrllkGvkeidiaatlehlrdqrpglvktkdqfefalt
|
|||||||||
subfamily_PTPRA_pd | Subfamily PTPRA | 826-876 | 1.2e-07 | 26.0 | In-house | 50-98 (330) | alignment | ||
Range on Protein: 826-876
Range on HMM: 50-98/330.0
CTIGYSEENKPFNRFKNITVYDDNRIILATNPNLDmcQREYINASYVDGYS
. . |||| ||. || || .|.||.. . . .|||||..|||
lelaskeenkeknrvvnilPydfsrvilsvkeGve..esdyinasfidGyk
|
|||||||||
subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 832-878 | 1.2e-07 | 26.1 | In-house | 44-88 (318) | alignment | ||
Range on Protein: 832-878
Range on HMM: 44-88/318.0
EENKPFNRFKNITVYDDNRIILATNPnlDMCQREYINASYVDGYSSN
. || ||. ||. ||. |. | . . . .||||.|.||| ..
pvnkaknryanilaydhtrvkLqmle..geegsDyinanyidGyrrk
|
|||||||||
subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 815-877 | 1.7e-07 | 25.0 | In-house | 26-86 (392) | alignment | ||
Range on Protein: 815-877
Range on HMM: 26-86/392.0
THSLKSGEEKPCTIGYSEENKPFNRFKNITVYDDNRIILATNPnlDMCQREYINASYVDGYSS
| | . . | |.. | |.. ||.||| || .|..| |. ...|.||||.... .
fhdlpgpdiypqtvaqkeinlkknryknilpydsarvklevid..dipdsdylnasyipsfdn
|
|||||||||
subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 822-876 | 1.9e-07 | 25.6 | In-house | 44-96 (298) | alignment | ||
Range on Protein: 822-876
Range on HMM: 44-96/298.0
EEKPCTIGYSEENKPFNRFKNITVYDDNRIILATNPnlDMCQREYINASYVDGYS
||. ... ..||| ||. .| .| |..| .. . . .|||||....|.
eeeekevarkpenkkkNRyadiialdssRvvLeked..adeesdYiNAsflhayk
|
|||||||||
fn3 | Fibronectin type III domain | 324-389 | 2.4e-07 | 24.0 | Pfam-A | 3-76 (85) | alignment | ||
Range on Protein: 324-389
Range on HMM: 3-76/85.0
PNDVKGFILNASSIKVNWTNS----IGTNGYVIEYTTGGVT--RNVVSTSEDE--VVLTNLSPMSTYTISVYSY
| ... ...|. ..|. . || .|| . | . . ....... |.||.| | ..|...|...
PenlsvsevtstsltlsWsppkdgggpitgYeveyrekgggeewkeftvprtttsvtltgLkpgteYefrVqav
|
|||||||||
subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 903-966 | 2.4e-07 | 24.7 | In-house | 216-279 (290) | alignment | ||
Range on Protein: 903-966
Range on HMM: 216-279/290.0
GGPVVVHCSDTVSRSGVYCSVSIALeQCKAEG-VVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVI
|||||||| . |.| . .. ..| |. .| .|. .. .|.|.|. ..| || . ...
sGpvvvhcsaGiGrtGtfvaievgl.qilldGkeldlldlvralrnsrlnsvqvdiqylalveil
|
|||||||||
subfamily_Sponge-PTP7_pd | Subfamily Sponge-PTP7 | 907-971 | 3.5e-07 | 24.5 | In-house | 1-65 (69) | alignment | ||
Range on Protein: 907-971
Range on HMM: 1-65/69.0
VVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFK
||||| |.| . .. . . . |.| .||.| . .|. .| | ..| |.| . .|
vvhcssGtGrtGtfiaimvemarikseklvdifnnvqymrkcrpmmvmneneymfihdalvealk
|
|||||||||
subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 824-877 | 4.3e-07 | 24.3 | In-house | 37-88 (288) | alignment | ||
Range on Protein: 824-877
Range on HMM: 37-88/288.0
KPCTIGYSEENKPFNRFKNITVYDDNRIILATNPNLDmcQREYINASYVDGYSS
| |.| .|.. ||..|| || .|. | .. . . .||||||.||. .
ksvtagrlavnakknRyrnilpyDekrvklkkleeea..gaDYinasyidgekk
|
|||||||||
subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 895-966 | 5.2e-07 | 23.6 | In-house | 192-265 (281) | alignment | ||
Range on Protein: 895-966
Range on HMM: 192-265/281.0
IHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAE-GVVDVFQVTKAIRRS-KPGAVTTLEQYTSIYDVI
| |. . | |.||| | ||| .| |||. .. . |. |. .| . . .| ||.|| |. |.
ilrkirarstppvihcsagvgrsgtlmaveialqsihshftlpdikqivshlrvtgraasvqtlqqymliwkvl
|
|||||||||
subfamily_PTPN12_pd | Subfamily PTPN12 | 817-877 | 6.6e-07 | 23.5 | In-house | 23-81 (290) | alignment | ||
Range on Protein: 817-877
Range on HMM: 23-81/290.0
SLKSGEEKPCTIGYSEENKPFNRFKNITVYDDNRIILATNPNLDmcQREYINASYVDGYSS
.|. .. . . | .|||. ||.|.| || .|. | .. . . . .||||... | ..
kykaekvysteagekeenvkknrykDilPydksrvelskieeee..gsdYinanfikgveg
|
|||||||||
subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 815-877 | 7.8e-07 | 23.2 | In-house | 25-85 (315) | alignment | ||
Range on Protein: 815-877
Range on HMM: 25-85/315.0
THSLKSGEEKPCTIGYSEENKPFNRFKNITVYDDNRIILATNPnlDMCQREYINASYVDGYSS
| | . . ... ..| . ||.||| .| .|..| | ...||||||. .. .
fhdlpdPdiyrqrvaretinfkknryknilPldsarvklevid..dsPdsdyinasyiksvdd
|
|||||||||
subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 903-971 | 9.1e-07 | 23.2 | In-house | 209-278 (307) | alignment | ||
Range on Protein: 903-971
Range on HMM: 209-278/307.0
GGPVVVHCSDTVSRSGVYCSVSIALEQ-CKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFK
||||||| | ||| ..|. .. . . |. .. . .| .. |. | || .. |. ||
tnpvvvhcsaGvGrsGtivaislvqdkmiaGinckdmkklveelrsqrhyaiqteaqylylhrvlleyfl
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 834-877 | 1.6e-06 | 23.1 | Pfam-A | 1-40 (235) | alignment | ||
Range on Protein: 834-877
Range on HMM: 1-40/235.0
NKPFNRFKNITVYDDNRIILatnpN-----LDmcqreYINASYVDGYSS
|| ||.|.|..||..|. | . | ||||.||.||..
nkkknRykdilpydktrvkl....kgsegpsd.....YInAnyvkgyke
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 834-877 | 1.6e-06 | 23.1 | In-house | 1-40 (235) | alignment | ||
Range on Protein: 834-877
Range on HMM: 1-40/235.0
NKPFNRFKNITVYDDNRIILatnpN-----LDmcqreYINASYVDGYSS
|| ||.|.|..||..|. | . | ||||.||.||..
nkkknRykdilpydktrvkl....kgsegpsd.....YInAnyvkgyke
|
|||||||||
subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 817-876 | 3.5e-06 | 20.4 | In-house | 26-83 (515) | alignment | ||
Range on Protein: 817-876
Range on HMM: 26-83/515.0
SLKSGEEKPCTIGYSEENKPFNRFKNITVYDDNRIILATNPnlDMCQREYINASYVDGYS
| . | |. | | . ||.||| || .|..| | . .|.||||. ..
dlpgpniypqtvaqeeinfkknryknilPydsvrvklevin..dnPhsdyfnasyipsfd
|
|||||||||
subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 822-873 | 4.3e-06 | 20.8 | In-house | 21-66 (283) | alignment | ||
Range on Protein: 822-873
Range on HMM: 21-66/283.0
EEKPCTIGYSEENKPFNRFKNITVYDDNRIILATNPNldmcqrEYINASYVD
.....| ..|||..||...| ..| .|. | .... .||||...
pdldadiasadenkrknrnqeivpadqwrvelksesr......dyinavfip
|
|||||||||
subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 901-970 | 5.4e-06 | 20.2 | In-house | 221-289 (310) | alignment | ||
Range on Protein: 901-970
Range on HMM: 221-289/310.0
IGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDvIDMYF
. ||.||||| . | .| ... ..... . ||. .| ...|. . | ||. | . . |
vrhgpcvvhcsagkdrlyvvvalklkidkldrglkvdaeevktellksraiciqtelqyliidr.vriif
|
|||||||||
subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 816-877 | 6.4e-06 | 20.3 | In-house | 31-90 (315) | alignment | ||
Range on Protein: 816-877
Range on HMM: 31-90/315.0
HSLKSGEEKPCTIGYSEENKPFNRFKNITVYDDNRIILATNPNLDmcQREYINASYVDGYSS
|. |. .| . ||| ||. || || |. | | . . .|.||...|||.
esipggqlhpldvakkienkqknryiniiaydksrvqlpllendp..hsdyvnanfidGynk
|
|||||||||
subfamily_PTPN14_pd | Subfamily PTPN14 | 822-873 | 6.7e-06 | 20.3 | In-house | 37-85 (300) | alignment | ||
Range on Protein: 822-873
Range on HMM: 37-85/300.0
EEKPCTIGYSEENKPFNRFKNITVYDDNRIILATNPNLdmcQREYINASYVD
|. .. . .||.. ||||.. |.|||. |... . . .||||| .
edallstaklpenaeknrfkdvlPyednrvelsptken...stgyinassik
|
|||||||||
subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 832-878 | 7.4e-06 | 20.5 | In-house | 59-103 (319) | alignment | ||
Range on Protein: 832-878
Range on HMM: 59-103/319.0
EENKPFNRFKNITVYDDNRIILATNpnLDMCQREYINASYVDGYSSN
..|| ||. || .| |.. | . .|||||.|.|| ..
dqnkdknriinilafdknvvklerl..iGeefsdyinasfvtGyqrk
|
|||||||||
subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 831-877 | 8.4e-06 | 20.2 | In-house | 6-50 (250) | alignment | ||
Range on Protein: 831-877
Range on HMM: 6-50/250.0
SEENKPFNRFKNITVYDDNRIILATNPNLDMCqrEYINASYVDGYSS
.|| ||. .| .| |..| .. . . .|||||...||.
kpqnkeknryadiialdssrvvLekekgdkes..dyinasflhgyde
|
|||||||||
subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 827-874 | 8.5e-06 | 20.1 | In-house | 41-86 (325) | alignment | ||
Range on Protein: 827-874
Range on HMM: 41-86/325.0
TIGYSEENKPFNRFKNITVYDDNRIILATNPnlDMCQREYINASYVDG
.. ||| |||||. .| .|..| | | . .||||||.
kvamkpenkaknrfknvvaldksrvvletkk..ddpssdyinasylrd
|
|||||||||
subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 832-878 | 9.7e-06 | 20.3 | In-house | 23-67 (284) | alignment | ||
Range on Protein: 832-878
Range on HMM: 23-67/284.0
EENKPFNRFKNITVYDDNRIILATNpnLDMCQREYINASYVDGYSSN
..|| ||. .| .| |.. | . .|||||.. || ..
dqnkdknrighilafdknvvklerl..iGeefsdyinasfitGyqrk
|