Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 1270-1486 | 1.3e-79 | 262.1 | In-house | 2-235 (301) | alignment | ||
Range on Protein: 1270-1486
Range on HMM: 2-235/301.0
LNDLGNHVACCHSDSnayFSEQFKDLYSGNDKQCSVGLNGMNKPLNRFRNIVPYDDNIITLKLP---GVAQHEYINASYIHGYSKARKFIAAQGPMKKTL
|.|||.|||..||.. |.||.|.|..|.||.|.|||. .||.||||.||..|||| |.|| ..|.||||||||.|||...|||||||||||||
ledlgthvaakhsnk...feeqykelkegedksctvglseenkalnrfknitvyddnriilkpkpnldlcqreyinasyidgysekkkfiaaqgpmkktl
VDFWCLIWQEKPASVVMLTNLVEDSKTKCEQYWPQCLNEIEQFGPFSVTLLEDYVMPDYVIRNISVTLQDGSG--------------EVHALTQYHLTTW
||||.|||||||.|.||.||| |..|.|||||||.. .| |.||||.||| ...|.||.|||...|..||||. . . ..|...| |
vdfWrliwqekpvsivmvtnlkegtkskceqywpnseaeseefgpftvtlvneqvyPdfvirqlnvkiqdgsnngyierkfkvksdksswdvlqlqvtdW
PDHGV-PEYATPLMTLHKRVMSS--SAKGPILVHCSA
|..|| .|..| |. ... .. .||..||||.
pqdGvvreprtvLqviddvihrqqkigggpvvVHCSd
|
|||||||||
subfamily_PTPRD_pd | Subfamily PTPRD | 1267-1487 | 6.4e-74 | 244.6 | In-house | 4-224 (564) | alignment | ||
Range on Protein: 1267-1487
Range on HMM: 4-224/564.0
PISLNDLGNHVACCHSDSNAYFSEQFKDLYSGNDKQCSVGLNGMNKPLNRFRNIVPYDDNIITL-KLPGVAQHEYINASYIHGYSKARKFIAAQGPMKKT
||. ..| .||| ...|.. |.|..|.. .|. .... . .||. ||. |||.|| . . | |..|. . .|||||.|.|| | ...||.|||...|
pipvaelkehvaklkansdlkfeeeykkieegqqftweaankpaNkaKNRyanivaYdhsRVvLskvegdegsDYINAsfidgyrkrkayIAtqgPlaet
LVDFWCLIWQEKPASVVMLTNLVEDSKTKCEQYWPQClNeIEQFGPFSVTLLEDYVMPDYVIRNISVtLQDGSGEVHALTQYHLTTWPDHGVPEYATPLM
. ||| ..|... ...||||.|.| .|.||..|||. . |..| . ||| | . . ||.||.... . | |.. .|.| | ||||||||.||.|.
iedFWRmvweqnsstiVmltkleEkgkvkchkYWPek.g.tetygeltVtleeeeeladyeirtfkl.kkkkssesreVrqFhFtsWPdhgvpesatslL
TLHKRVMSS--SAKGPILVHCSAG
.| ..| .. . .|||.||||||
dlirkvralnepdagPivVhCSaG
|
|||||||||
subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 1266-1487 | 7.2e-74 | 243.7 | In-house | 2-226 (305) | alignment | ||
Range on Protein: 1266-1487
Range on HMM: 2-226/305.0
LPISLNDLGNHVACCHSDSNAYFSEQFKDLYSGnDKQCSVGLNGMNKPLNRFRNIVPYDDNIITLKL-PGVAQHEYINASYIHGYSKARKFIAAQGPMKK
.|.|.|| ... ...|. . .|.| ||. .... || . .|| ||...|...||. | |. . . ...||||||..||.. |.|.||||.|.
kiialddlaayikearvysdkgleaqykslyee.eesidvgkkeankaknrlkeitlldddriiltekeslddsdyinasyvdgykrkkkyivaqgPlkn
TLVDFWCLIWQEKPASVVMLTNLVEDSKTKCEQYWPQCLNEIEQFGPFSVTLLEDYVMPDYVIRNISVTLQDGSGEVHALTQYHLTTWPDHGVPEYATPL
|..||| ||..||. ..||||.|||. | ||.||||. .| ..||.|||.| . ..||..|..... .|.. | ....||.||.|||||||..|| |
tvadfWrliveekvstivmltklveggkdkCrqYWpesktekkefgefsvelksektasdyieRklkisiededkesrtvlqyqltdWPdhGvpqfatsl
MTLHKRVMSSSAKG---PILVHCSAG
..| |||. . |. |.|||||||
lslikrvqkdqkkdkgvpllVhCsag
|
|||||||||
subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 1487-1601 | 3e-73 | 241.1 | In-house | 187-301 (301) | alignment | ||
Range on Protein: 1487-1601
Range on HMM: 187-301/301.0
GWNIVQFQVIGWMNDGVLRDPRTVLQVIDDVIHRQQKIGGGPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQYITIY
.|...|.||. |..|||.|.||||||||||||||||||||||.||||||||||.||||..||.||||||||||||||||||..|||||||||||||..||
swdvlqlqvtdWpqdGvvreprtvLqviddvihrqqkigggpvvVHCSdtVsrsGvYcsvsiglEQckaegVVdvfqvtkavrrskpgaVtTLeqytsiy
EALEMYLAINSTYSN
....|||..||||.|
dvidmylqlnstyan
|
|||||||||
subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 1268-1487 | 8e-67 | 220.1 | In-house | 2-226 (290) | alignment | ||
Range on Protein: 1268-1487
Range on HMM: 2-226/290.0
ISLNDLGNHVACCHSDSNAYFSEQFKDLYSGN-DKQCSVGLNGMNKPLNRFRNIVPYDDNIITLK-LPGV--AQHEYINASYIHGYSKARKFIAAQGPMK
| ....|..|| |. | | .||| | ||. ... ||| ||.||||.|||.|||| |||. ..| ..|||||.||.||......||.|||..
ipvdkfgefvanghakgnegfrnqfkmldsgesehtvtvgltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgykekkqyiatqgpvs
KTLVDFWCLIWQEKPASVVMLTNLVEDSKTKCEQYWPQClnEIEQFGPFSVTLLEDYVMPDYVIRNISVTLQDGSGEVHALTQYHLTTWPDHG-VPEYAT
.|||||| |||||| . .||||| .|. |.|| ||||. . ...|.||..||.. .. .|..|...|. .. .|. . .|||..|.|...| |....|
ntlvdFWkliwqekvtiivmltniieegkvkCqqYWpds..dtkaygefsikllneetlneyierklevknknsagakqsvtqyqitnwdstgkvtnpqt
PLMTLHKRV--MSSSAKGPILVHCSAG
|....... . . ...|.||||..
illvieemyktqrkrgntsivvHCSdt
|
|||||||||
0051299 | (Phosphotyrosine protein) phosphatases II | 1266-1488 | 3.3e-65 | 215.7 | In-house | 3-230 (288) | alignment | ||
Range on Protein: 1266-1488
Range on HMM: 3-230/288.0
LPISLNDLGNHVACCHSDSNAYFSEQFKDLYSGN-DKQCSVGLNGMNKPLNRFRNIVPYDDNIITLKL-PGVAQHEYINASYIHGYSKARKFIAAQGPMK
.||...| ..| . ...... |.|..|.| . | ..|..| |.. ||...|.|||.. . |. .|| . |||||||.|| . |||||.|||..
teisveellklvlkllangltglleefeellsllpdltlsaallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyidgynlkrkfIatqgPlp
KTLVDFWCLIWQEKPASVVMLTNLVEDSKTKCEQYWPQclNEIEQFGPFSVTLLEDYVMPDYVIRNISVTLQD---GSGEVHALTQYHLTTWPDHGVPEY
.|. ||| ..|... .||||.|||....||.||||. .. ...|...||||. .|..||..|.. || | |.||.. |..| |.|||||||..
ntvedFWrmvweqnvrvIvmltklvelgrekcaqYwpl..ggsltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpds
ATPLMTLHKRVMSS--SAKGPILVHCSAGW
...|... ..|... | .||..||||||
pellldflrlvrkalasgggpvvVHCsaGv
|
|||||||||
subfamily_PTPRB_pd | Subfamily PTPRB | 1264-1487 | 3.6e-63 | 208.3 | In-house | 3-228 (293) | alignment | ||
Range on Protein: 1264-1487
Range on HMM: 3-228/293.0
QTLPISLNDLGNHVACCHSDSNAYFSEQFKDLYS-GNDKQCSVGLNGMNKPLNRFRNIVPYDDNIITL-KLPGVAQHEYINASYIHGYSKARKFIAAQGP
.. ||.|... .||. ..||.. |||....| . |.|..... . .|. ||..||.||| . . | .| . .. .||||.||.||. |.|||.|||
kskpiklekfeehvkkmkadsdlrfseeyeelkavgkdqavkaaelavnraknrytnilpydhsrvkLaalkdesgsDYinanyipgynsprefiatqGP
MKKTLVDFWCLIWQEKPASVVMLTNLVEDSKTKCEQYWPQCLNEIeQFGPFSVTLLEDYVMPDYVIRNISVTLqdgSGEVHALTQYHLTTWPDHGVPEYA
. .|. ||| ..|..| .||||.||| |.|||.|||. ... ..| .|||... .. |.|||..... . | . ..||| |.|||||||| .
lpetvddfWrmvwekkssiivmltqlvekgkvkCeeYWPadeepv.lyGdikvtlvaeeeledwvirelkiek...ekeerkvrqyhftsWpdhgvPekt
TPLMTLHKRVMSS----SAKGPILVHCSAG
..|... ..| .. ..|.||.||||||
ktlldfvrtvreaiektaskrPivvhCsaG
|
|||||||||
0050432 | (Phosphotyrosine protein) phosphatases II | 1268-1488 | 4.6e-63 | 208.7 | In-house | 26-243 (308) | alignment | ||
Range on Protein: 1268-1488
Range on HMM: 26-243/308.0
ISLNDLGNHVACchSDSNAYFSEQFKDLYSGND-KQCSVGLNGMNKPLNRFRNIVPYDDNIITLklpGvAQHEYINASYIHGY--SKARKFIAAQGPMKK
.|. || ... ... ...|.|..|.| . ..||.| ||..||...|.||| . . | . . ||||||..|| . |||||.|||...
lsvldllkllek..aldlglleeefeellsvkplleysvallpenkdkNrykdilpydhsRVkl...d.egsdYInAsyvdgyssklprkfIatqgPlpn
TLVDFWCLIWQEKPASVVMLTNLVEDSKTKCEQYWPQCLN-EIEQFGPFSVTLLEDYVMPDYVIRNISVTLQDGSgEVHALTQYHLTTWPDHGVPEYATP
|. ||| ..|... .||||.|||... ||.|||| |. .....|.|.||||. .|..||..|.. .| ... |.. .|..| |.|||||||.....
tvedFwrmvweqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseevlddytvrtleltnlgdg.esrtvthfhytnWpdhgvPpspei
LMTLHKRVMSSSAKGPILVHCSAGW
|... ..| .| .|||.||||||
lldflelvrkslpggpivVHCsaGv
|
|||||||||
0040438 | (Phosphotyrosine protein) phosphatases II | 1272-1488 | 1.8e-62 | 206.8 | In-house | 4-220 (317) | alignment | ||
Range on Protein: 1272-1488
Range on HMM: 4-220/317.0
DLGNHVACCHSDSNAYFSEQFKDLYSGNDKQCSVGLNGMNKPLNRFRNIVPYDDNIITLKL-PGVAQHEYINASYIHGYSKARKFIAAQGPMKKTLVDFW
|| ... .. .. ...|.|.||.| . .||.. ||..||...|.|||.. . |. .|. . ||||||..|... |||||.|||...|. |||
dlllalldllksdftalleefedllslkldtysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPlpntvedFw
CLIWQEKPASVVMLTNLVEDSKTKCEQYWPQclNEIEQFGPFSVTLLEDYVMPDYVIRNISVTLQdGSGEVHALTQYHLTTWPDHGVPEYATPLMTLHKR
..|... ..||||.|.|... ||.||||. .| ..|.|.||||. ........|.. |. |..|.. .|..| |.|||||||.. ..| . ..
rmvweqgvtvivmLteleelgrekcaqYwpl..getltygdftvtllseeelagitlrtlevedl.gdsesrtvthfhytgWpdhgvppspdllldflea
VMSS--SAKGPILVHCSAGW
| .. . .||.|||||||
vrealedpggpvlVHCsaGv
|
|||||||||
0046845 | (Phosphotyrosine protein) phosphatases II | 1288-1488 | 4.5e-62 | 205.3 | In-house | 2-215 (284) | alignment | ||
Range on Protein: 1288-1488
Range on HMM: 2-215/284.0
FSEQFKDLYSGNDK---QCSVGLNGMNKPLNRFRNIVPYDDNIITLKLPGV--AQHEYINASYIHGY-----SKARKFIAAQGPMKKTLVDFWCLIWQEK
. |.|. |.| . | ..||.| |. .||...|.|||.. . || .. ..||||||..|| . .||||.|||...|. ||| ..|...
leeefeellsltvklllslsvallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqn
PASVVMLTNLVEDSKTKCEQYWPQClNEIEQFGPFSVTLLEDYVMPDYVIRNISVTLQDGSGEVHALTQYHLTTWPDHGVPEYATPLMTLHKRVMSS---
.||||.|||....||.||||. .| ..|.|.||||. .|..||..|....| . .||.. .|..| |.|||||||.....|... . | ..
vrvIVmltelvengrekcaqYwple.gevltygdftvtllseevkddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrellen
-SAKGPILVHCSAGW
. .|||.||||||
lpgggpivVHCsaGv
|
|||||||||
subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 1268-1487 | 1.5e-61 | 202.9 | In-house | 2-221 (287) | alignment | ||
Range on Protein: 1268-1487
Range on HMM: 2-221/287.0
ISLNDLGNHVACCHSDSNAYFSEQFKDLYS--GNDKQCSVGLNGMNKPLNRFRNIVPYDDNIITLKlpgVAQHEYINASYIHGYSKARKFIAAQGPMKKT
|... .|. || | .| |..||. | . .... ... ||..||...|...|.. . || ...||||..| ||.....||.|..|| .|
ipvekfgefvakghakgnegfknqftvleqvtqredevthniasqnkdknRltqilvpdnyrvllk...gehpdyinavfidgykekkafiiaesPmfnt
LVDFWCLIWQEKPASVVMLTNLVEDSKTKCEQYWPQCLNeiEQFGPFSVTLLEDYVMPDYVIRNISVTLQDGSGEVHALTQYHLTTWPDHG-VPEYATPL
...||.||..... .|||... |. . .| ||||. . .|.....||.. |. .|..|.. |. .. .|. . ..||..|.|...| |.|..| |
arnfWkliddrnvtaivmlcqekendeevcyqyWpeeks..vvlGeyniellneevnagyierklevknknkagdkqqvkqyqitnWdstgkvtepqtil
MTLHKRVMS--SSAKGPILVHCSAG
. ..... . .....|.||||..
lvieemyktqrkrgntsivvhCsdt
|
|||||||||
0045450 | (Phosphotyrosine protein) phosphatases II | 1262-1488 | 1.3e-60 | 201.0 | In-house | 3-245 (307) | alignment | ||
Range on Protein: 1262-1488
Range on HMM: 3-245/307.0
IPQTLPISLNDLGNHVACCHSDSNAYFSEQFKDLYSGNDK---QCSVGLNGMNKPLNRFRNIVPYDDNIITLKLPGV--AQHEYINASYI--------HG
.| |.|.. .| .|. . |... . ..|..|.| ... .|..| ||..||...|.|||.. . |. .. . ||||||. .|
lplslfidalkllllvllllldfltgllkefekllsvtvfllgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldg
YSKARKFIAAQGPMKKTLVDFWCLIWQEKPASVVMLTNLVEDSKTKCEQYWPQClNEIEQFGPFSVTLLEDYVMPDYVIRNISVTLQDGSGEVHALTQYH
| . |||||.|||...|. ||| ..|... .||||.|||. . || ||||. .| ..|.| ||||. .....|..|.. || ||.||.. .|..|
ydlkrkfIatqgPlpetvedFwrmlweqgvtvivmltelvelgrekcaqywPde.geeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfh
LTTWPDHGVPEYATPLMTLHKRVMS----SSAKGPILVHCSAGW
|.|||||||.. .| . ..|.. .. .||.|||||||
ytgwpdhgvppsfeelldfieevrkaleelpkggpvlVHCsaGv
|
|||||||||
0036941 | (Phosphotyrosine protein) phosphatases II | 1282-1488 | 1.3e-60 | 200.6 | In-house | 9-218 (297) | alignment | ||
Range on Protein: 1282-1488
Range on HMM: 9-218/297.0
SDSNAYFSEQFKDLYSGN-DKQCSVGLNGMNKPLNRFRNIVPYDDNIITLklpGVAQHEYINASYIHGYSKARKFIAAQGPMKKTLVDFWCLIWQEKPAS
....|.....|..|.. . .||.|. |...||...|.|||.. . | . . ||||||. ||. |||||.|||...|. ||| ..|... .
llflalllkefeellpllllgslsvallpenleknRykdilpydhtRVkl...ddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqnvtv
VVMLTNLVEDSKTKCEQYWPQCLNEIEQFGPFSVTLLEDYV--MPDYVIRNISVTLQdGSGEVHALTQYHLTTWPDHGVPEYATPLMTLHKRVMSSS---
.||||.|||. . ||.|||| .| ..|.|.||||. .| .||..|.. || |.||.. .|..| |.||||||||....|. . ..| .
Ivmltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdt.gngesrtvthfhytgwpdhgvpespaslldfielvrkvlkll
-AKGPILVHCSAGW
.||.|||||||
psggpvlVHCsaGv
|
|||||||||
0043336 | (Phosphotyrosine protein) phosphatases II | 1267-1488 | 4.1e-60 | 199.0 | In-house | 1-221 (278) | alignment | ||
Range on Protein: 1267-1488
Range on HMM: 1-221/278.0
PISLNDLGNHVACCHSDSNAYFSEQFKDLYSGNDKQCSVGLNGMNKPLNRFRNIVPYDDNIITLKL-PGVAQHEYINASYIHGYSKARKFIAAQGPMKKT
||| .|| .... .. .... ....|..|.| . .|..| ||..||...|.||| . . |.| .|. . ||||||. ||.. |||||.|||...|
pisvkdllkallelllnlktllllefeellsfkldtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpet
LVDFWCLIWQEKPASVVMLTNLVEDSKTKCEQYWPqclNEIEQFGPFSVTLLEDYVMPDYVIRNISVTLqDGSGEVHALTQYHLTTWPDHGVPEYATPLM
. ||| ..|... ..||||.|||....|| |||| .. ...|.|.||||. ....||..|.. || |.||.. |.|| . |||||||| ..|.
vedFwrmvwelgvttivmLtelvelgrvkcaqYwp...ggsltygdftvtllkeehlddytvrtlevtn.lgdgesrtvthyhylgwpdhgvpeslslll
TLHKRVMSS--SAKGPILVHCSAGW
. |.|.. . .||.|||||||
dflkavrealedsngpvlVHCsaGv
|
|||||||||
0039614 | (Phosphotyrosine protein) phosphatases II | 1258-1488 | 1.1e-59 | 197.7 | In-house | 4-233 (297) | alignment | ||
Range on Protein: 1258-1488
Range on HMM: 4-233/297.0
FDPKIPQTLPISLNDLGNHVACCHSDSNAYFSEQFKDLYSGNDKqCSVGLNGMNKPLNRFRNIVPYDDNIITLKLPGV--AQHEYINASYIHGYSK-ARK
. ... .. ||.|. | .. . . .|. .. ..|..|.| .. .|..| ||..||...|.|||.. . || .. . ||||||. ||.. ||
lrdallesipiplsvldlllllekansktllllefeellslkpd.ysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrk
FIAAQGPMKKTLVDFWCLIWQEKPASVVMLTNLVEDSKtKCEQYWPQCLNeieQFGPFSVTLLEDYVMPDYVIRNISVTLqdgSGEVHALTQYHLTTWPD
|||.|||...|. ||| ..|... ..||||.|||... ||.||||. . ..|.|.||||. .. ..|..|...|| .||.. .|... | |||
fIatqgPlpetvedFwrmvweqgvtvivmLtklvelgr.kcaqywpeegg...tygdftvtllkvehldgytvrtlevtn...ngesrtvthfqytgwpd
HGVPEYATPLMTLHKRVMSSS----AKGPILVHCSAGW
||||.... |. . . |.. .||.|||||||
hgvppslellleflelvrealaelpkggpvlVHCsaGv
|
|||||||||
0047943 | (Phosphotyrosine protein) phosphatases II | 1282-1488 | 1.9e-59 | 196.7 | In-house | 8-216 (273) | alignment | ||
Range on Protein: 1282-1488
Range on HMM: 8-216/273.0
SDSNAYFSEQFKDLYSGN-DKQCSVGLNGMNKPLNRFRNIVPYDDNIITLklpGVAQHEYINASYIHGYSKARKFIAAQGPMKKTLVDFWCLIWQEKPAS
....... |.|..|.| . .||.| || .||...|.|||.. . | | . ||||||. || . |||||.|||...|. ||| ..|...
llgltllleefelllslkplltysvallpenkdknrykdilpydhsrvkl...gdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvweqnvrv
VVMLTNLVEDSKTKCEQYWPQCLNE-IEQFGPFSVTLLEDYVMPDYVIRNISVTLQDGSgEVHALTQYHLTTWPDHGVPEYATPLMTLHKRVMS----SS
.||||.|||... ||.||||. .| ...|.|.||||. .. .||..|.. .| . . |.. |..| |.|||||||.. ..|... . |.. .
iVmLtelvelgrekcaqYwpleggelsltygkftvtllseetkddytvrtleltnlgtg.esrtvthfhytgwpdhgvppslesllefielvrkalealp
AKGPILVHCSAGW
.||..||||||
sngpvvVHCsaGv
|
|||||||||
subfamily_PTPRG_pd | Subfamily PTPRG | 1269-1487 | 1.7e-58 | 193.3 | In-house | 2-230 (563) | alignment | ||
Range on Protein: 1269-1487
Range on HMM: 2-230/563.0
SLNDLGNHVACCHSDSNAYFSEQFKDLYSGND---KQCSVGLNGMNKPLNRFRNIVPYDDNIITLK-LPGVAQ-HEYINASYIHGYSKARKFIAAQGPMK
.... .||| .|.|.. |||.|..| | ... . || || |||.|| ..|. |||. . ..||||.||.|| |...|||.|||.|
pvkefakhvaslhadgdigfseefealqsetiskdldaehsqkpenkrKnRylnivaydrsRvklsplpgkkkklDYinAnyidGyqkskafiatqgplk
KTLVDFWCLIWQEKPASVVMLTNLVEDSKTKCEQYWPQclNEIEQFGPFSVTLLEDYVMPDYVIRNISVTL---QDGS--GEVHALTQYHLTTWPDHGVP
.|. ||| .||... | .||.|||||. . ||..|||. .| |..| ..||| | |. | .|.... .... ... .||| |.|||||||
dtfddFWrmiWeqnvaiivmitnlvergrrkcdvYWPk..desetygalqvtlieeevlalytvrtlviknlklkkkkqcdteklvrqyhytkWPdhgvP
EYATPLMTLHKRVMSSSAK--GPILVHCSAG
|...| .. |. . . |||.||||||
ehslpvLifvkkssaankaeaGPivvHcsaG
|
|||||||||
subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 1267-1487 | 2e-58 | 192.9 | In-house | 4-226 (319) | alignment | ||
Range on Protein: 1267-1487
Range on HMM: 4-226/319.0
PISLNDLGNHVACCHSDSNAYFSEQFKDLYSGNDKQCSVGLNGMNKPLNRFRNIVPYDDNIITL-KLPGVAQHEYINASYIHGYSKARKFIAAQGPMKKT
.| ...| ... .| .. .. ..||.| ..... . . ||. ||..||..|| ..| .|.|| . .|||||.| || . .||||.|.|...|
eievqeLkerlkalastgetllekefkllkeavndtfdsaskeenkkknryqnilaydrtrvvlseldgvegsdyinasfidgyqerekfiatqaPlent
LVDFWCLIWQEKPASVVMLTNLVEDSKTKCEQYWPQclNEIEQFGPFSVTLLEDYVMPDYVIRNISVTLQDGSGEVHALTQYHLTTWPDHGVPEYATPLM
. ||| ..|.|. |||||.||| | |...|||. ...|..| . |||.|. . ||.||.... . . | ..... | ||||.|||.|| |.
iedfWrmvWeeessivvmltklveklkvklkkywpe..enfeeyGrlivtleeeeeledyiirklklnkkssevetRevkhfqyteWpdhdvPekatsll
TLHKRVMSSSAK---GPILVHCSAG
| ||. | | ||| ||||||
dllkrirksrektqsgPivvhCsaG
|
|||||||||
subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 1270-1487 | 4.9e-58 | 191.5 | In-house | 6-222 (288) | alignment | ||
Range on Protein: 1270-1487
Range on HMM: 6-222/288.0
LNDLgNHVACCHSDSNAYFSEQFKDL-YSGNDKQCSVGLNGMNKPLNRFRNIVPYDDNIITLKL-PGVAQHEYINASYIHGYSKARKFIAAQGPMKKTLV
.... ..|| . .... |||... | ...|. ..| . |.. ||.|||.||| . . || . .|. .|||||||.|. | .|.||.|||. .|.
ispv.akvakksarnrtgfseeynsLaalektksvtagrlavnakknRyrnilpyDekrvklkkleeeagaDYinasyidgekkkkkyiatqgPladtvn
DFWCLIWQEKPASVVMLTNLVEDSKTKCEQYWPQClNEIEQFGPFSVTLLEDYVMPDYVIRNISVTlqdGSGEVHALTQYHLTTWPDHGVPEYATPLMTL
||| |....| .||||.|||. |||||.|||. .. ...| . |||.|. . |.| |.. . ... .|||. ..|||||||| ..||. |
dfWelvyenktstivmltelveggktkCeeYWPda.dkpknyGsvtvtlveskeledfvlrkllle...kkkteleitqyqylaWpdhgvPeskapllel
HKRVMSSS--AKGPILVHCSAG
. | .. |||.||||||
lrqvkvanqadtgpiivhCsaG
|
|||||||||
DSPc_SM00195 | 1288-1488 | 1.3e-56 | 187.2 | In-house | 2-206 (263) | alignment | |||
Range on Protein: 1288-1488
Range on HMM: 2-206/263.0
FSEQFKDLYSGN-DKQCSVGLNGMNKPLNRFRNIVPYDDNIITLKLPG-VAQHEYINASYIHGYSKARKFIAAQGPMKKTLVDFWCLIWQEKPASVVMLT
..|.|..| . . .|... . || ||..||.|||.. . || . ...||||.|| |..| .|.||.|||...|. ||| ..|.|| .||||
lkeefekleestspketteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlt
NLVEDSKTKCEQYWPQCLNEIEQFGPFSVTLLEDYVMP-DYVIRNISVTLQDGsGEVHALTQYHLTTWPDHGVPEYATPLMTLHKRVMSSSA--KGPILV
. .|. |.||..|||. .. |.|| .||.| | .. ....|....| .. | . .|||. ..|||||||. ..... | . | .|. .|||.|
eeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegk.eetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivV
HCSAGW
|||||
hCsaGv
|
|||||||||
PTPc_SM00194 | 1288-1488 | 1.3e-56 | 187.2 | In-house | 2-206 (263) | alignment | |||
Range on Protein: 1288-1488
Range on HMM: 2-206/263.0
FSEQFKDLYSGN-DKQCSVGLNGMNKPLNRFRNIVPYDDNIITLKLPG-VAQHEYINASYIHGYSKARKFIAAQGPMKKTLVDFWCLIWQEKPASVVMLT
..|.|..| . . .|... . || ||..||.|||.. . || . ...||||.|| |..| .|.||.|||...|. ||| ..|.|| .||||
lkeefekleestspketteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlt
NLVEDSKTKCEQYWPQCLNEIEQFGPFSVTLLEDYVMP-DYVIRNISVTLQDGsGEVHALTQYHLTTWPDHGVPEYATPLMTLHKRVMSSSA--KGPILV
. .|. |.||..|||. .. |.|| .||.| | .. ....|....| .. | . .|||. ..|||||||. ..... | . | .|. .|||.|
eeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegk.eetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivV
HCSAGW
|||||
hCsaGv
|
|||||||||
subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 1268-1487 | 3e-56 | 185.8 | In-house | 2-223 (318) | alignment | ||
Range on Protein: 1268-1487
Range on HMM: 2-223/318.0
ISLNDLGNHVACCHSDSNAYFSEQFKDLYSGNDK-QCSVGLNGMNKPLNRFRNIVPYDDNIITLK-LPGVAQHEYINASYIHGYSKARKFIAAQGPMKKT
||..|| .||. ... . ..||... | ... |. .|| ||. ||..||. . |. | |. . .||||.|| || . ...||||.|. .|
isvedleshvrrlresGelllseeyerlsrseetvtslkslepvnkaknryanilaydhtrvkLqmlegeegsDyinanyidGyrrkkayiaaqaPlpet
LVDFWCLIWQEKPASVVMLTNLVEDSKTKCEQYWPQclNEIEQFGPFSVTLLEDYVMPDYVIRNISVTLqDGSGEVHALTQYHLTTWPDHGVPEYATPLM
. ||| ..|. . | .||||...| .|.|...|||. .. ...| |.| |. . |||.|...|| ... |. ||| |.|||.|||| .. |.
ieDfWrmvWeqnsavivmltqeeergkakvhryWPs..kgsrsygklvvelkeevelsdyvlrefkvtr.teeeesrqvrqyhytsWpdegvpesgasll
TLHKRVMSSS---AKGPILVHCSAG
| ..| . .|||.||||||
dlvrqvskaqqksgagpivvhCsaG
|
|||||||||
subfamily_Ptp69D_pd | Subfamily Ptp69D | 1268-1487 | 1.4e-54 | 180.3 | In-house | 4-229 (307) | alignment | ||
Range on Protein: 1268-1487
Range on HMM: 4-229/307.0
ISLNDLGNHVACCHSDSNAYFSEQFKDLY-SGNDKQCSVGLNGMNKPLNRFRNIVPYDDNIITL-KLPGVAQHEYINASYIHGYSKARKFIAAQGPMKKT
|.. || . . . |.. . . .. | . ||...|. . |. ||. .|...|.. . | |..| .. .|||||.|.|| . .||||||.|. |
iaiddleealksrkrdtdfglakeyekLeareidkstkvsekkenalknRyedikafDktRvkLkkingkedsdYinasfikgykekkkfiaaqdPveat
LVDFWCLIWQEKPASVVMLTNLVEDSKTKCEQYWPQClnEIEQFGPFSVTLLEDYVMPDYVIRNISVTLQDGSG----EVHALTQYHLTTWPDHGVPEYA
. ||| .|.. . .|||.|| | .. ||..|||. .. |.| |.| . ..||.||...|. .. .. . . ..||| |.|.| ||| |
igDfWRmiaeqevtlivmlsnlteknrkkcakYWpie..devqygdilvklvseekhsdyiiReldvskkkeesgevedsrkvvqyhytgWkDskvPeva
TPLMTLHKRV--MSSSAKGPILVHCSAG
. |. | ..| . . ..||.||||||
rgllklieqvrelyklnrsPivvhCsaG
|
|||||||||
subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 1267-1487 | 4.7e-54 | 178.4 | In-house | 5-222 (315) | alignment | ||
Range on Protein: 1267-1487
Range on HMM: 5-222/315.0
PISLNDLGNHVACCHSDSNAYFSEQFKDLYSGNDKQCSVGLNGMNKPLNRFRNIVPYDDNIITLKLPGVAQH-EYINASYIHGYSKARKFIAAQGPMKKT
|| |..| .|| .. .. | .... . |. . | . .|| ||. ||..|| . | | . .| .|.||..| ||.| |..|||||| .
pipldqlityvaqkkastkngfkqdyesipggqlhpldvakkienkqknryiniiaydksrvqlpllendphsdyvnanfidGynkkrryiaaqgpnvas
LVDFWCLIWQEKPASVVMLTNLVEDSKTKCEQYWPQClneIEQFGPFSVTLLEDYVMPDYVIRNISVTLQDgsgEVHALTQYHLTTWPDHGVPEYATPLM
. ||| |...|. . .||||||||. | |.|.||| .|...||. .. | .| .| .||. .| ... . |.|.|.||| |||.|..|||
vkdfwrlvfeedigkivmltnlvegekrkaekywpdk...kviyGkitvtrkseevnteytvrtlsvvfgd...nirevvqlhytswpdmgvpkytiplm
TLHKRVMSS--SAKGPILVHCSAG
|...|. .. |.|.||||||
nlirtvkqhhtnsvgaivvhcsaG
|
|||||||||
0045098 | (Phosphotyrosine protein) phosphatases II | 1289-1489 | 1.4e-53 | 177.4 | In-house | 11-218 (278) | alignment | ||
Range on Protein: 1289-1489
Range on HMM: 11-218/278.0
SEQFKDLYSGNDKQCSVGLNGMNKPLNRFRNIVPYDDNIITlklpgvaqhEYINASYIHGYsKaRKFIAAQGPMKKTLVDFWCLIWQEKPASVVMLTNLV
.| . | |. .....| |...||...|.||| . . .|||||||.|| . .||||.|||...|. ||| ..|... ..||||.||
lefefllllgipseitpalylgnldknRykdilpydhsrVk.........dYINAsyidgy.p.kkfIatqgPlpstvadfwrmlwelgitvivmltelv
EDSKTKCEQYWPQclNEIEQFGPFSVTLLEDYVMPDYVIRNISVTLQ---DGSGEVHALTQYHLTTWPDHGVPEYA--TPLMTLHKRVMSS---------
|... ||.|||| .. ...|.|.||||. .|..||..| . || . ..| . .|..|...|||||||.. ... | ... .
elgrekcaqywpe..ggsltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslll
------SAKGPILVHCSAGWN
. .||.|||||||..
sslllldsggpvlVHCsaGvg
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 1311-1488 | 3.7e-53 | 175.7 | Pfam-A | 1-181 (235) | alignment | ||
Range on Protein: 1311-1488
Range on HMM: 1-181/235.0
NKPLNRFRNIVPYDDNIITLKLPGVAQHeYINASYIHGYSKARKFIAAQGPMKKTLVDFWCLIWQEKPASVVMLTNLVEDSKTKCEQYWPQCLNEIEQFG
|| ||...|.|||.. . || . .. ||||.|..||.. .||||.|||.|.|. ||| ..|||| ..||||.|.| ...||.||||. .| ...|
nkkknRykdilpydktrvklkgsegpsd.YInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesltyg
PFSVTLL-EDY-VMPDYVIRNISVTLQDGSGEVHALTQYHLTTWPDHGVPEYATPLMTLHKRVMSSS--AKGPILVHCSAGW
..|.| . . .|..|..... .... | . ..|.|.|.|||||||| ...|. | ..| .|. .||..||||||
dikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGv
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 1311-1488 | 3.7e-53 | 175.7 | In-house | 1-181 (235) | alignment | ||
Range on Protein: 1311-1488
Range on HMM: 1-181/235.0
NKPLNRFRNIVPYDDNIITLKLPGVAQHeYINASYIHGYSKARKFIAAQGPMKKTLVDFWCLIWQEKPASVVMLTNLVEDSKTKCEQYWPQCLNEIEQFG
|| ||...|.|||.. . || . .. ||||.|..||.. .||||.|||.|.|. ||| ..|||| ..||||.|.| ...||.||||. .| ...|
nkkknRykdilpydktrvklkgsegpsd.YInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesltyg
PFSVTLL-EDY-VMPDYVIRNISVTLQDGSGEVHALTQYHLTTWPDHGVPEYATPLMTLHKRVMSSS--AKGPILVHCSAGW
..|.| . . .|..|..... .... | . ..|.|.|.|||||||| ...|. | ..| .|. .||..||||||
dikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGv
|
|||||||||
subfamily_PTPN6_pd | Subfamily PTPN6 | 1286-1487 | 5e-53 | 175.1 | In-house | 26-237 (306) | alignment | ||
Range on Protein: 1286-1487
Range on HMM: 26-237/306.0
AYFSEQFKDLYSGNDKQ---CSVGLNGMNKPLNRFRNIVPYDDNIITLKLPGVAQHEYINASYIHGYS--KARKFIAAQGPMKKTLVDFWCLIWQEKPAS
| |.|.|..| . |. . | || ||..||.|.|.. ..|| |.|....||||.||.. . . ...||.|| ...|. ||| ..|||.
agfeeefeelqqeeakkllsrkegakpenkeknryknilPfDhtrvilkepsvpgsdyinanyikkevkgsdksyiatqgclettvsdFWrmvwqensrv
VVMLTNLVEDSKTKCEQYWPQCLNEIEqFGPFSVTLLEDYVMPDYVIRNISVTLQDGSGEVHALTQYHLTTWPDHGVPEYATPLMTL----HKRVMSSS-
.||.|. || .| || .|||. .. | .| ||| ... . ||..|..||. .. ..| . . ||| ..|||||||. .. . ... ...
ivmttkevErgkekCarYWPdeeekee.yGkisvtnvseksladYilRelsvskkkkkkeerevfqyhfksWPdhgvpkdpgavLdfledvnrkqeelee
-AKGPILVHCSAG
.|||.||||||
aeagpivvhCsaG
|
|||||||||
0040439 | (Phosphotyrosine protein) phosphatases II | 1303-1488 | 7.7e-53 | 175.0 | In-house | 3-190 (249) | alignment | ||
Range on Protein: 1303-1488
Range on HMM: 3-190/249.0
CSVGLNGMNKPLNRFRNIVPYDDNIITLKL-PGVAQHEYINASYIHGYSKARKFIAAQGPMKKTLVDFWCLIWQEKPASVVMLTNLVEDSKTKCEQYWPQ
.||.| ||..||...|.||| . . |. ||. . |||||||.|| |.|||.|||...|. ||| ..|... ..||||.||| . ||.||||.
ysvallpenkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywpl
clNEIEQFGPFSVTLLEDYVMPDYVIRNISVTLQdGSGEVHALTQYHLTTWPDHGVPEYATPLMTLHKRVMSSS----AKGPILVHCSAGW
.. ..| |.||||. .|..||..|.. .| . ||.. .... | |||||||.. .|. . ..|.. .||.|||||||
..ggsleygdftvtllsvevkddytvrtleltnl.ydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGv
|
|||||||||
subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 1281-1487 | 3.7e-52 | 172.4 | In-house | 22-233 (298) | alignment | ||
Range on Protein: 1281-1487
Range on HMM: 22-233/298.0
HSDSNAYFSEQFKDLYSGND----KQCSVGLNGMNKPLNRFRNIVPYDDNIITLKL-PGVAQHEYINASYIHGYSKARKFIAAQGPMKKTLVDFWCLIWQ
.. . . ....|. | |... .. .|. . || ||. .|...| . |. . . .|||||..|.|.. |||.|.|...|..||| ....
kkkkltgyalefqrlnsvsseieeeekevarkpenkkkNRyadiialdssRvvLekedadeesdYiNAsflhaykgrnafiatqaPltetvedFWrmvte
EKPASVVMLTNLVEDSKTKCEQYWPQclNEIEQFGPFSVTLLEDYVMPDYVIRNISVTLQDGSgEVHALTQYHLTTWPDHGVPEYATPLMTLHKRVMSSS
|. ...||||||.| |||...|||. .. |..| ..|.||..... |...|.. |. .. . . . . | | |.|||.||||.|| ...| ..| |
edigtiVmltnleeldktkyhkywPd..egketygeitvsllskeefadlivrklkvskkkee.kerevrqlhftsWpdkgvpenatsvldllrkvrasq
-AKG--PILVHCSAG
| |..|.||||
qqagnkpvivqCsaG
|
|||||||||
subfamily_PTPRA_pd | Subfamily PTPRA | 1266-1487 | 5.7e-52 | 171.6 | In-house | 12-238 (330) | alignment | ||
Range on Protein: 1266-1487
Range on HMM: 12-238/330.0
LPISLNDLGNHVACCHSDSNAYFSEQFKDLYSGN-DKQCSVGLNGMNKPLNRFRNIVPYDDNIITL-KLPGVAQHEYINASYIHGYSKARKFIAAQGPMK
|. ...| . . .| | | |.|. | .|. . . . . || ||. ||.||| . . | .. || . .|||||.|.|| . |||||||| .
fplpvekleeeirirsaddnklfreefnalPagpiqatlelaskeenkeknrvvnilPydfsrvilsvkeGveesdyinasfidGykekdkfiaaqGPke
KTLVDFWCLIWQEKPASVVMLTNLVEDSKTKCEQYWPQclNEIEQFGPFSVTLLEDYVMPDYVIRNISVT-LQDGS--GEVHALTQYHLTTWPDHGVPEY
.|. ||| .||. | |..||||.| | ..||.||||. . . .| |.. .. |. || .|.. |. | |.. .. ..|.|.|.||| |||
etvedfwrmiweqksativmltelkerkeekcaqywPd..eGlvtyGnirvevedetvlvdytvrkflvqqlpdatrekksrlvrqfhftswPdvGvPfe
ATPLMTLHKRVMSS--SAKGPILVHCSAG
. .. | |.| . ||| ||||||
piGmlkllkkvkklnqqsagpivvhcsaG
|
|||||||||
0042113 | (Phosphotyrosine protein) phosphatases II | 1304-1488 | 6.2e-52 | 171.8 | In-house | 2-187 (245) | alignment | ||
Range on Protein: 1304-1488
Range on HMM: 2-187/245.0
SVGLNGMNKPLNRFRNIVPYDDNIITLKLPGVAQ-HEYINASYIHGYSKARKFIAAQGPMKKTLVDFWCLIWQEKPASVVMLTNLVEDSKTKCEQYWPQc
||.| ||..||...|.|||.. . |. .| . ||||||..|| .||||.|||...|. ||| ..|... ..||||...|... ||.||||.
svallpenkdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywpl.
lNEIEQFGPFSVTLLEDYVMPDYVIRNISVTLqDGSGEVHALTQYHLTTWPDHGVPEYATPLMTLHKRVMS---SSAKGPILVHCSAGW
.|. ..| |.||||. ....||..|...|| .|..|.. ..|| . |||||||.. | ....| . ....||.|||||||
.gesltygdftvtllseehlddytvrtlevtn.lgddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGv
|
|||||||||
subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 1282-1487 | 1.7e-51 | 169.9 | In-house | 14-219 (515) | alignment | ||
Range on Protein: 1282-1487
Range on HMM: 14-219/515.0
SDSNAYFSEQFKDLYSGNDKQCSVGLNGMNKPLNRFRNIVPYDDNIITL-KLPGVAQHEYINASYIHGYSKARKFIAAQGPMKKTLVDFWCLIWQEKPAS
. . |||.|.|| | .| . .| . ||..||.||| . . | . ...|.|||||... . .||.||| | .. ||| |..||...
nrhttlfseefhdlpgpniypqtvaqeeinfkknryknilPydsvrvklevindnPhsdyfnasyipsfdndkayiasqgPnkasvddfWrlvlqenvtt
VVMLTNLVEDSKTKCEQYWPQCLNEIEQFGPFSVTLLEDYVMPDYVIRNISVTLQDGsgeVHALTQYHLTTWPDHGVPEYATPLMTLHKRVMSSSAK--G
..|.|.| |. | || .|||. . .|| ..| |. . ..|.. |. .| ....||.|.| |||.|||. .. |. | | | .. .
iamvtklkegdkikcgkyWPdkpgdsvkfGsikvelvsleactggikrkltvlkgdd...srtvtqfhfteWPdkGvpkhtssllklikevkadhgqyth
PILVHCSAG
|...|||||
pliihcsaG
|
|||||||||
subfamily_PTPN12_pd | Subfamily PTPN12 | 1303-1487 | 1.7e-51 | 169.9 | In-house | 32-217 (290) | alignment | ||
Range on Protein: 1303-1487
Range on HMM: 32-217/290.0
CSVGLNGMNKPLNRFRNIVPYDDNIITLKLPG-VAQHEYINASYIHGYSKARKFIAAQGPMKKTLVDFWCLIWQEKPASVVMLTNLVEDSKTKCEQYWPQ
..| . |. ||...|.||| . ..|. . . .||||..|.| .. ..||||||. ||| ||| .||. . |||. ..|| |.|||.|||.
teagekeenvkknrykDilPydksrvelskieeeegsdYinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCerYWpe
CLNEIEQFGPFSVTLLEDYVMP-DYVIRNISVTLQdgsGEVHALTQYHLTTWPDHGVPEYATPLMTLHKR--VMSSSAKGPILVHCSAG
.| .||.|.||| |. . |..|| . |. | .| . ..|.| | |||||||. |..|. | . . .| . |..||||||
egeeelefgefevtleeekavdddflirtLkveaq...kesrkvyqfhYtaWPDhgvPssaksllelielvrelqesedaPlvvhCsaG
|
|||||||||
subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 1283-1487 | 7.1e-51 | 167.9 | In-house | 16-220 (315) | alignment | ||
Range on Protein: 1283-1487
Range on HMM: 16-220/315.0
DSNAYFSEQFKDLYSGNDKQCSVGLNGMNKPLNRFRNIVPYDDNIITL-KLPGVAQHEYINASYIHGYSKARKFIAAQGPMKKTLVDFWCLIWQEKPASV
| |||.|.|| . . |. . .| . ||..||.|.| . . | . ...|||||||... . . .||.||| | .. ||| ...|||....
rhtalfseefhdlpdPdiyrqrvaretinfkknryknilPldsarvkleviddsPdsdyinasyiksvdddkayiasqgPlkasvddfwrmvlqekvtti
VMLTNLVEDSKTKCEQYWPQCLNEIEQFGPFSVTLLEDYVMPDYVIRNIsVTLQdgSGEVHALTQYHLTTWPDHGVPEYATPLMTLHKRVMSSSA--KGP
||.|.. |. | || ||||. . .|| ..|.||. | |.|.. || . | | . .||...| |||.||.. .. |. | | | .. . .
vmvtkkqegdkikcrqywPdrkadsvefGsikvellsleadtdgvarkl.vtrk..seesrtvtqfqftewPdkGvdkqtssllklikevkadngkkefs
ILVHCSAG
.|||||||
llvhcsaG
|
|||||||||
subfamily_PTPRK_pd | Subfamily PTPRK | 1269-1487 | 1.9e-50 | 166.5 | In-house | 5-220 (314) | alignment | ||
Range on Protein: 1269-1487
Range on HMM: 5-220/314.0
SLNDLGNHVACCHSDSNAYFSEQFKDLYSGndkqCSVGLNGMNKPLNRFRNIVPYDDNIITLK-LPGVAQHEYINASYIHGYSKARKFIAAQGPMKKTLV
.|| ...|. . . | |... |. | . . |. ||. .|..|| ..|. . | .. .||||..| .| ....||..|||...|.
rvadllqsiallkraegygfkeeyeslfeg....wdaakkdenreknrsgdilaydrsrvflitidgdpssdyinaalidsykrpaafivtqgPlqetvk
DFWCLIWQEKPASVVMLTNLVEDSKTKCEQYWPQclnEIEQFGPFSVTLLEDYVMPDYVIRNISVTL-QDGSGEVHALTQYHLTTWPDHGVPEYATPLMT
||| |...|. ||.||||.||| .. || .|||. . |..|.. |.|.| . ..|.| .|. . | |.. . |.. ..||||.|| .|| |..
dfWrlvydencasivmltelvevgrvkClkyWPe...dtevygdikvelvetellaelvvrifrveklargqeeirevrqfqflgWpdhdvPvsatgllk
LHKRVMSSS--AKGPILVHCSAG
| .|| .|. .|.|.||||||
lvrrvkksqeeeaGrivvhCsaG
|
|||||||||
0037934 | (Phosphotyrosine protein) phosphatases II | 1303-1488 | 4e-50 | 166.0 | In-house | 2-189 (243) | alignment | ||
Range on Protein: 1303-1488
Range on HMM: 2-189/243.0
CSVGLNGMNKPLNRFRNIVPYDDNIITLklPGvaqHEYINASYIHGYskaRKFIAAQGPMKKTLVD----FWCLIWQEKPASVVMLTNLVEDSKTKCEQY
.|..| .|.. ||...|.|||.. . | .| . ||||..| .. ...|| |||...|. | || ..|... ..||||.||| .. ||.||
fsiallpenlsknrysdilpydhsrvkl..eg...sdyinanliyvt...prliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqy
WPqclNEIeQFGPFSVTLLEDYVMPDYVIRNISVTLQDGSGEVHALTQYHLTTWPDHGVPEYATPLMTLHKRVM----------SSSAKGPILVHCSAGW
|| .|. ..|.|.||||. ....||..|..... | ..... ..|| . |||||||. ..|. ... | . .||.|||||||
wp...gev.tygdftvtllseehlddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGv
|
|||||||||
subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 1304-1487 | 2.4e-48 | 159.6 | In-house | 2-185 (250) | alignment | ||
Range on Protein: 1304-1487
Range on HMM: 2-185/250.0
SVGLNGMNKPLNRFRNIVPYDDNIITLKL-PGVAQHEYINASYIHGYSKARKFIAAQGPMKKTLVDFWCLIWQEKPASVVMLTNLVEDSKTkCEQYWPqc
||. . || ||. .|...| . |. | . .|||||..|||.. . |||.|||...|..||| ....|| ...||||||.| || ..||||
svakkpqnkeknryadiialdssrvvLekekgdkesdyinasflhgyderkafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqywP..
LNEIEQFGPFSVTLLEDYVMPDYVIRNISVTLQDGSGEVHaLTQYHLTTWPDHGVPEYATPLMTLHKRVMSSSAK---GPILVHCSAG
.. |..| |.||.. .. ||..|.. .. . ..|.. . |.| ..||| ||||.|| . | |.| .| . .|..|.||||
vekaekyGdvtvsllskeefadytkrklklskakkaderi.vrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaG
|
|||||||||
subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 1310-1487 | 3.5e-48 | 159.6 | In-house | 60-234 (319) | alignment | ||
Range on Protein: 1310-1487
Range on HMM: 60-234/319.0
MNKPLNRFRNIVPYDDNIITLK-LPGVAQHEYINASYIHGYSKARKFIAAQGPMKKTLVDFWCLIWQEKPASVVMLTnlvedsKTKCEQYWPQCLNEIEQ
|| ||. ||...| |.. |. | |. .|||||.. || . |.||||||.. || ||| .||. . ...|.|| | || ||||. .. |.
qnkdknriinilafdknvvklerliGeefsdyinasfvtGyqrkdkyiaaqGPldntladfWrmiweyncstivllt......kdkcsqywplkivikee
FGPFSVTLLEDYVMpdYVIRNISVTLQDGSGEVHALTQYHLTTWPDHGVPEYATPLMTLHKRVMS----SSAKGPILVHCSAG
. .|...|. ||.|.| .. . .. .||.|. |||.|||.|...||.| |.| . .|.||||||
rfkvkvdsveetae..yvvrdielsedgkekdirkitqfhflGwpdvGvpdypsdlmrlvkkvrhltskenhranivvhcsaG
|
|||||||||
subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 1310-1487 | 1.2e-47 | 157.8 | In-house | 24-198 (284) | alignment | ||
Range on Protein: 1310-1487
Range on HMM: 24-198/284.0
MNKPLNRFRNIVPYDDNIITLK-LPGVAQHEYINASYIHGYSKARKFIAAQGPMKKTLVDFWCLIWQEKPASVVMLTnlvedsKTKCEQYWPQCLNEIEQ
|| ||. .|...| |.. |. | |. .|||||.| || . |.||.|||.. || ||| .||. . ...|.|| | || ||||. .. |.
qnkdknrighilafdknvvklerliGeefsdyinasfitGyqrkdkyiatqGPldntladfWrmiweyncstivllt......kdkcsqywplkivikee
FGPFSVTLLEDYVMpdYVIRNISVTLQDGSGEVHALTQYHLTTWPDHGVPEYATPLMTLHKRVMS----SSAKGPILVHCSAG
. .|...|. ||.|.| .. . .. ..|.|. |||.|||.|...||.| |.| . .|.||||||
rfkvkvdsveesee..yvvrdielsedgkekdirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsag
|
|||||||||
subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 1275-1487 | 4.4e-47 | 155.5 | In-house | 4-218 (281) | alignment | ||
Range on Protein: 1275-1487
Range on HMM: 4-218/281.0
NHVACCHSDSNAYFSEQFKDLYS-GNDKQCSVGLNGMNKPLNRFRNIVPYDDNIITL-KLPGVAQHEYINASYIHGYSKARKFIAAQGPMKKTLVDFWCL
.|.. ....|| | |....|.. |.|. . . |. ||..||| || ... . . .||||... ||.. ...||.|||. ..||.|| .
khlkqlsqndnaGfieeyeklaaigvdntataskadenvlknrYsnivaYDatrvkvtpneenkntDYinanfvpgykgekeyiatqgPvPaslvafWqm
IWQEKPASVVMLTNLVEDSKTKCEQYWPQCLNEIeQFGPFSVTLLEDYVMPDYVIRNISVtlQDGSGEVHALTQYHLTTWPDHGVPEYATPLMTLHKRV-
.|..| .||.|. .| .| || .|||. .|. ..| . |. .. . |. |.... . ||| ..| . |.|||||||. .. |. .| |
vweqkvsaivmvtreieagklkChrYWPddnsel.kygdvtvkstaeeekatyierkfkl..eresgetreveqlaytaWPdhGvPattkellefrkevl
--MSSSAKGPILVHCSAG
... | |...|||||
kltekktkaplvihCsaG
|
|||||||||
subfamily_PTPN3_pd | Subfamily PTPN3 | 1290-1487 | 2.8e-46 | 152.7 | In-house | 19-218 (280) | alignment | ||
Range on Protein: 1290-1487
Range on HMM: 19-218/280.0
EQFKDLYSGN-DKQCSVGLNGMNKPLNRFRNIVPYDDNIITLKlpgVAQHEYINASYIH----GYSKARKFIAAQGPMKKTLVDFWCLIWQEKPASVVML
||. || . . ..|. | . ||.|.|.|||. ..|| .. .||||.|. . . ..||.|||..|| ||| ..|..| .|||
aqfeqlyrkkpglaisaarkpenlsknryrdilpydatrvklk...esetdyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqksslivml
TNLVEDSKTKCEQYWPQcLNEIEQFGPFSVTLLEDYVMPDYVIRNISVTLQDgSGEVHALTQYHLTTWPDHGVPEYATPLMTLHKRVMSS--SAKGPILV
|.|||. ..|| ||||. .. ..| |||.. .. ||.|.. .. .. . | . ..| . |||||||. .. .... .|| . ... |..|
ttlverGrvkChqyWPe.tedeleygefsvkcekedetksyvlrelvlkdke.tkeerkilqlqylaWpdhgvPddsadflefvervrklrsgkeePvvv
HCSAG
|||||
hCsaG
|
|||||||||
subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 1311-1487 | 2.8e-45 | 149.4 | In-house | 3-182 (237) | alignment | ||
Range on Protein: 1311-1487
Range on HMM: 3-182/237.0
NKPLNRFRNIVPYDDNIITLKLPGVAqHEYINASYIHGYSK-ARKFIAAQGPMKKTLVDFWCLIWQEKPASVVMLTNLVEDSKTKCEQYWPQClNEIEQF
|| ||. ||| || . . || .| . .||||.|..|. .|.||||||.. . ||| ..|||| . .|||| |.| . || .|||. .. . .
nkiknrygnivaydhsrvvlkgagsg.sdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpst.dqpaay
GPFSVTLLEDYVMPDYVIRNISVTLQDGSGEVHALTQYHLTTWPDHGVPEYATPLMTLHKRVMSSSAK----GPILVHCSAG
| ..|.| . . || .| . .. . || . ||..|.|||.|||.... |. . |... | . || ..|||||
gvltvslkkkeefsdytvrslllskrltlkevrlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsag
|
|||||||||
subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 1269-1487 | 1.8e-43 | 143.9 | In-house | 6-231 (325) | alignment | ||
Range on Protein: 1269-1487
Range on HMM: 6-231/325.0
SLNDLGNHVACCHSDSNAYFSEQFKDLYSGNDKQCSVGLNGMNKPLNRFRNIVPYDDNIITLKLPGVAQH-EYINASYIHGYSKARKFIAAQGPMKKTLV
.. .| .|| ... . |. .|. | | . . | || |||.|.|..| . . |. . . . .||||||.. . | |.||| |. .|.
avvnlvehvekkkaqdqdgfahefgllpsddgiakkvamkpenkaknrfknvvaldksrvvletkkddpssdyinasylrddkkkdvflaaqaPltatin
DFWCLI--WQekpASVVMLTNLVEDSKTKCEQYWPQCLNEIEQFGPFSVTLLEDYVMPDYVIRNISVTlQDGSGEVHALTQYHLTTWPDHGVPEYATPLM
|.| |. |. .|||...| .. | .| .|||. . . .||.. | | . ||| | . | | || .. |..| .|.| ||... . |.
dlWrlvldWr...csvvvvlneldlgkdrcavywpkemgksktfGglevklrtieeisdyvhrvldvk.qvkkGetrsvkqfqlqswddmGvqkrpatli
T-------LHKRVMS-SSAKGPILVHCSAG
. ...|| . . | .|||||||||
silqlvkavservtantkastpilvhcsaG
|
|||||||||
subfamily_PTPN23_pd | Subfamily PTPN23 | 1284-1488 | 3.6e-43 | 142.4 | In-house | 13-223 (288) | alignment | ||
Range on Protein: 1284-1488
Range on HMM: 13-223/288.0
SNAYFSEQFKDLYSGND---KQCSVGLNGMNKPLNRFRNIVPYDDNIITLKlpgVAQHEYINASYIHGYS-KARKFIAAQGPMKKTLVDFWCLIWQEKPA
.. . ..||.| . .| .. |. . .. ||.|.|.||| | ..|. . .|||||.... | . .|||.|.|...|| ||| .....|
gktaldkkfkeleqkqdkearkrsiaiaklyseknrsrdilPyDhnRvklr...gskDDYinAsfvkdlspgcPdfiatqaPlqstlnDFWlmvyeqkss
SVVMLTNLVEDSKTKCEQYWPQCLNEIEQFGPFSVTLLEDYVMPDYVIRNISVTLQDGSgEVHALTQYHLTTWPDHGVPEYATPLMTLHKRVMS------
.|||.. | |.|...|||. .| ..||..|||| . .. .| |..... .| . .|. .. .||.||..|||. |. . . | |
viVmllskeelgkpkvdrYwPedkgetvkfgdlsvtlksvretethvervlkletldad.avksvshlqltsWpelGvPasPetllqfldevesayeavq
SSAKGPILVHCSAGW
.| |..||||||
rksktPlvvhCsaGv
|
|||||||||
subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 1284-1487 | 1.7e-42 | 140.2 | In-house | 7-209 (283) | alignment | ||
Range on Protein: 1284-1487
Range on HMM: 7-209/283.0
SNAYFSEQFKDLySGNDKQCSVGLNGMNKPLNRFRNIVPYDDNIITLKLPGVaqhEYINASYIH---GYSKARKFIAAQGPMKKTLVDFWCLIWQEKPAS
.| | |..| | | |... . . ||. ||...|||.| ... || .||||..| | . .|.|.||.|...| |||| ....|| ..
nnklfrevlkrl.svpdldadiasadenkrknrnqeivpadqwrvelksesr...dyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekita
VVMLTNLVEDSKTKCEQYWPQclNEIEQFGPFSVTLLEDYVMPDYVIRNISVTLQDGSGEVHALTQYHLTTWPDHGVPEYATPL--MTLHKRVMSSSAKG
.||||.| || . || ||||. . |..|.| ||| ... ..|... . . . . |. | . | . | | . . . | ||
ivmltklqedlrikCsqyWPk..rGsedyGeftvtlrkettsnsfiikelllrvnssakstlllahyqvidWleygeqaiinslvkfnkvislqteskkg
PILVHCSAG
||.||||.|
PivvhCstg
|
|||||||||
subfamily_PTPN13_pd | Subfamily PTPN13 | 1291-1487 | 2e-41 | 137.1 | In-house | 16-212 (273) | alignment | ||
Range on Protein: 1291-1487
Range on HMM: 16-212/273.0
QFKDLYSG-NDKQCSVGLNGMNKPLNRFRNIVPYDDNIITLKLPGVaqheYINASYIHGYSK--ARKFIAAQGPMKKTLVDFWCLIWQEKPASVVMLTNL
.||.| ..|.|| . || ||.||..|||. ..|. | |||||.|. ..||.|||. .| ||| ..|. | ..|.|.
efkelrelkpldtcevgkkkenkdknryrnvlPydetrvklgdegg....yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamvtle
VEDSKTKCEQYWPQCLNEIEQFGP-FSVTLLEDYVMPDYVIRNISVTlQDGSGEVHALTQYHLTTWPDHGVPEYATPLMTLHKRVMSSSA-KGPILVHCS
.|. | ||..|||. |. . . |.||. . ..|.|.. |. . |||.. ... ....||||||| |..|... ..| . .|||.||||
kekgkvkchrywPesknkklkvsnrlevellkvqkldgfvvralavk.dsesgesrevahlnfvkwPdhgvPssaaellqfvaevrrlqtdagPivvhcs
AG
||
aG
|
|||||||||
subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 1303-1487 | 3.7e-41 | 136.0 | In-house | 21-211 (274) | alignment | ||
Range on Protein: 1303-1487
Range on HMM: 21-211/274.0
CSVGLNGMNKpLNRFRNIVPYDDNIITLKLPGVAQH--EYINASYIHGYSKARK-FIAAQGPMKKTLVDFWCLIWQEKPASVVMLTNLVEDSKTKCEQYW
. . | .. ||...|.| . ..|. . .. .|||| ||.||.. | ..|.|||. .|. ||| .|.||. .||||.| | ..||..|.
eeldvfgsqt.knryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneqkCavyf
PQCLNE--IEQFGPFSVTLLEDYVMPDYVIRNISVTLQDGsgeVHALTQYHLTTWPDHGVPEYATPLMTLHKRVMSS----SAK-GPILVHCSAG
|. . |..| .... . || .|.... . . .. | | |||| .|. |..|. | . | .| .|| .|..||||||
Pdaedyeiserygdveikvekiverndysvrklvlkyler...ersvkhywytdWPdhksPddantlldlvleveesreeenaklapvvvhCsaG
|
|||||||||
subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 1267-1487 | 6.2e-41 | 135.4 | In-house | 9-227 (297) | alignment | ||
Range on Protein: 1267-1487
Range on HMM: 9-227/297.0
PISLNDLGNHVAccHSDSNAYFSEQFKDLYSGNDKQCSVGLNGMNKPLNRFRNIVPYDDNIITLKLPGVA-QHEYINASYIHGYSKarKFIAAQGPMKKT
|| | |. | .. . .|||.|..| . | .. | . .| . .|..||.||| . ..|. . . .|.|||...|. . ..|. | ||| |
piplsdfatlvq..knrhtdvfseeflclpeaniqpqtvaekkvnfeksRYkniLPydssRvkLaivnddpdsDyvnasfvkgnkh..rlittqmPmkat
LVDFWCLIWQEKPASVVMLTNLVEDSKtKCEQYWPQclNEIEQFGPFSVTLLEDYVMPDYVIRNISVTLQDgSGEVHALTQYHLTTWPDHGVPE-----Y
. ||| ....|... .|||... | | || .||.. . . .|| ||.|| .. |...|| .. . . . ||. . |||. |.. .
vadfWamvldeqvstivmlnddnerdk.kcaryWsd..kgvttfGdvsvvllsvsereGfikrelevtkgk.akarrvvkqyqfveWPdkaverkdsass
ATPLMTLHKRVMSSSAKGPILVHCSAG
|.. . . |. |.||.||||.||
llklisevrkdfsqnaegPllvhclaG
|
|||||||||
subfamily_PTPN9_pd | Subfamily PTPN9 | 1310-1486 | 7.4e-41 | 135.1 | In-house | 41-232 (297) | alignment | ||
Range on Protein: 1310-1486
Range on HMM: 41-232/297.0
MNKPLNRFRNIVPYDDNIITL-KLPGVAQHEYINASYIHGYSKARKFIAAQGPMKKTLVDFWCLIWQEKPASVVMLTNLVEDSKTKCEQYWPQCLNEIEQ
.| ||. ... ||. ..| |... . .||||... || . . |||.|||.||| ||| ..|... .|| | .|| . || ||||. .. ..
anleknrytdvlcydetrvvlakvdedeasdyinanfvdGykqkkafiatqGplkktvsdfWrmvWeqevlvivmttrvvergrlkcgqyWpleeessae
FGPFSVTLLEDYVMPDYVIRNISVTLQDgSGEVHALTQYHLTTWPDHGVPEYATPLMTLHKRVMSSSAK---------------GPILVHCSA
|| .||. .|. .. ||..| . .. . .| .| . ...|||.|||. |. |. . . | . |. ||.|||||
fgdlsvsnveveeeedykvrvleiknvk.teesrkvthfqflsWPdyGvPssaaslldvlekvrekqalavkelgdewkghpsgPPivvhcsa
|
|||||||||
subfamily_PTPN1_pd | Subfamily PTPN1 | 1299-1487 | 8.2e-41 | 134.6 | In-house | 20-211 (290) | alignment | ||
Range on Protein: 1299-1487
Range on HMM: 20-211/290.0
NDKQCSVGLNGMNKPLNRFRNIVPYDDNIITLKLpgvAQHEYINASYIHGYSKARKFIAAQGPMKKTLVDFWCLIWQEKPASVVMLTNLVEDSKTKCEQY
.| .... . |..|||.|.. ||| |.|. |. .||||| .. |..| .|||. .| || ..|..| .|||| ..|| ...|| ||
sdfptreaklpenrnlnryrdvspydhsrikler...adndyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvvekeqikcaqy
WPQCLN-EIEQFG--PFSVTLLEDYVMPDYVIRNISVTlQDGSGEVHALTQYHLTTWPDHGVPEYATPLMTLHKRVMSS----SAKGPILVHCSAG
||| . . .. ..|.|.. . |..| . .. . . | . ....| ||||| |||| . .. . .| .| | .|| ..|||||
wPqgeeekellledtklkvkliseerksyytvrllele.nlktqetreilhfhyttwpdfgvpespaaflkflfkvresGslssdvGpavihcsaG
|
|||||||||
subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 1310-1488 | 8.4e-41 | 134.7 | In-house | 7-185 (239) | alignment | ||
Range on Protein: 1310-1488
Range on HMM: 7-185/239.0
MNKPLNRFRNIVPYDDNIITL-KLPGVAQHEYINASYIHGYSKAR-KFIAAQGPMKKTLVDFWCLIWQEKPASVVMLTNLVEDSKTKCEQYWPQClneIE
.|| ||. ||| || . . | || . .||||||.. | . .||.|| .. . ||| ..|||. . .|||| |.| | || ||||.
vnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpds...ts
QFGPFSVTLLEDYVMPDYVIRNIsVTLQDGSGEVHALTQYHLTTWPDHGVPEYATPLMTLHKRVMSSSAKG--PILVHCSAGW
.. . ||| . |. ||.|| . | | | | . . |||.| |||.|||.||| .. |.... | | | ..|||||
kycnlrvtlrktevfadyiirtf.vmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagv
|
|||||||||
subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 1310-1488 | 1.1e-40 | 134.2 | In-house | 6-184 (239) | alignment | ||
Range on Protein: 1310-1488
Range on HMM: 6-184/239.0
MNKPLNRFRNIVPYDDNIITL-KLPGVAQHEYINASYIHGYSKAR-KFIAAQGPMKKTLVDFWCLIWQEKPASVVMLTNLVEDSKTKCEQYWPQClneIE
.|| ||. ||| || . . | || . .||||||.. | . .||.|| .. . ||| ..|||. . .|||| |.| | || ||||.
vnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpds...ts
QFGPFSVTLLEDYVMPDYVIRNIsVTLQDGSGEVHALTQYHLTTWPDHGVPEYATPLMTLHKRVMSSSAKG--PILVHCSAGW
.. . ||| . |. ||.|| . | | | | . . |||.| |||.|||.||| .. |.... | | | ..|||||
kycnlrvtlrktevfadyiirtf.vmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagv
|
|||||||||
subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 1489-1596 | 5.9e-40 | 132.3 | In-house | 179-286 (305) | alignment | ||
Range on Protein: 1489-1596
Range on HMM: 179-286/305.0
NIVQFQVIGWMNDGVLRDPRTVLQVIDDVIHRQQKIGGGPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQYITIYEA
...|.|. | ..|| . . ..|..|..| ..|.| | |..||||..|.||||..|..||||..|.|.|||||.|.|.|.......|.||.|| ...|
tvlqyqltdWPdhGvpqfatsllslikrvqkdqkkdkgvpllVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkmvqtldqYvflhda
LEMYLAIN
|. ..
ldelitcg
|
|||||||||
subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 1294-1487 | 1.1e-39 | 131.0 | In-house | 3-207 (270) | alignment | ||
Range on Protein: 1294-1487
Range on HMM: 3-207/270.0
DLYSGNDKQCSVGLNGMNKPLNRFRNIVPYDDNIITL-KLPGVAQHEYINASYIHGYSK-ARKFIAAQGPMKKTLVDFWCLIWQEKPASVVMLTNLVEDS
.| .. .. .. .| |||...|.| ..| .| . .|||| |..|... .|.|||.||.. || .|| .||.|| ..||.|.|.|.
eldkeetsesdlpeaargkklnRyadiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkg
KTKCEQYWPQCLNE--IEQFGPFSVTLLEDYVMPDYVIRNISVTlqdGSGEVHALTQYHLTTWPDHGVPEYAT------PLMTLH---KRVMSSSAKG-P
..|||.|||. .| ..| .|. |.. . |..... .. .|| . |. .. .||||||||. . |... .|. .. .|. |
rkkCerYWpaepkekvkledgkikvlalseekeegyiltrlrle...ekgeerrlvHfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaeP
ILVHCSAG
.|||||||
llvHcsaG
|
|||||||||
subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 1297-1487 | 5e-39 | 128.8 | In-house | 38-220 (287) | alignment | ||
Range on Protein: 1297-1487
Range on HMM: 38-220/287.0
SgndkqcsvglngmnKPLNRFRNIVPYDDNIITLKLPGVAQHEYINASYIHGYSKARKFIAAQGPMKKTLVDFWCLIWQEKPASVVMLTNLVEDSKTKCE
. ||. ...|.||. . | | .|||| |. .| . .|||||||. |. |||....... |||...| ||... ||
a..............vkknryadvlPiddtrvllsaegelGsdyinanyvasytddeafiaaqgPiaatvrdfwravletrsasvitmtreveearlkcy
QYWPQClNEIEQFGPFSVTLLE-DYVMPDYVIRNISVTLQDGSgEVHALTQYHLTTWPDHGVPEYATPLMTLHKRV-------MSSSAKGPILVHCSAG
.|||. . . | .||.||. | |.| .| . . .. | . . |..| .|||.... | |. . | ..| ||..||...|
kywPer.evPmrvGGysvvlldydikePeygvralrlidletr.earvvkqldllswPdkvlaPtavglirfvldvkqhielardasevGPlvvhddvG
|
|||||||||
subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 1272-1487 | 3.2e-37 | 123.0 | In-house | 6-222 (439) | alignment | ||
Range on Protein: 1272-1487
Range on HMM: 6-222/439.0
DLGNHVACCHSDSNAYFSEQFKDLYSGNDK-QCSVGLN--GMNKPLNRFRNIVPYDDNIITL-KLPGVAQHEYINASYIHGYSKARKFIAAQGPMKKTLV
.. .|| . . . |.| |. . | . . .| | ... ||.......| .|| ..||| . |||| ||.|| . . .||.||| |.|
efqehvekldknkqeifkeifekinstspdyaciaslaaqeydqtknrykdvgafdhtrvtlqeipgvphshyinanyikGyyddklyiatqgpkkettd
DFWCLIWQEKPASVVMLTNLVEDSKtkceqYWPQCLNeiEQFGPFSVTLLEDYVMPDYVIRNISVTLQ-DGSGEVHALTQYHLTTWPDHGVPEYATPLMT
||| |....| . .|||||||| | ||| . .| .| . .|.|||| . | . | . ... |.| ..|||. || |. ..
dfwrlviekktvtivmltnlvesyk.....ywpsdae..vcygdiavrvdrnielpnyvirgfkvfnerdttekertvlqfhyiawpdknvpaqashvld
LHKRVMSSS---AKGPILVHCSAG
. . . |. ||..||||||
flrainsandkeeygpvvvhcsag
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 1311-1593 | 3.6e-36 | 119.4 | In-house | 28-315 (319) | alignment | ||
Range on Protein: 1311-1593
Range on HMM: 28-315/319.0
NKPLNRFRNIVPYDDNIITL-KLPGVAQHEYINASYIHGYSKAR-KFIAAQGPMKKTLVDFWCLIWQEKPASVVMLTNLVEDSKTKCEQYWPQ--CLNEI
|. .|. |.|| . ..| . . . ||..|||. || .|. .|||| ..... ||| ..|. . .| ||.| | .| .|.| |..
skdksrvinvvPlPetrvvlqrigdddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlselGikvcaeylPtketldnt
EQFGPFSVTLLEDYVMPDYVIRNISVTLQDGSgEVHALTQYHLtTWPDHGVPEYATPLMTLHKRVMSS-----SAKGPILVHCSAGWNIVqFQVIGWMND
. .| . ||| . | |.| . . |.. | || | |.. .|| ..|... .| || . | . || . ... | .
slyGdilvtlkgrevkdryaistlllkrvdke.esrelthywy.kwleaevPaeeaaliamllevrsslksysleqanelreksatlets.mdadgskae
GVLRDPRTVLQVIDDVIHrqQKIGGGPIVVHCSDTVSRTGVYCAISIALEQCKAE-GVVDVFQVTKALKRSKPGAVTTLEQYITIYEALEMYL
. . | .. ||.|||||| | |||. | ||... . ||. |. ..| . || | ||| || | .|
agstssheingnissrsg..tresqGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefiykvlseya
|
|||||||||
subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 1490-1600 | 6.3e-35 | 115.4 | In-house | 180-290 (290) | alignment | ||
Range on Protein: 1490-1600
Range on HMM: 180-290/290.0
IVQFQVIGWMNDGVLRDPRTVLQVIDDVIHRQQKIGGGPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQYITIYEAL
..|.|. | ..| . .| |.|.|| ... | | | ..|||||||||.|..|.||. .....|| |||.||||| | .. ||| |.| .|| .|.. .
vtqyqitnwdstgkvtnpqtillvieemyktqrkrgntsivvHCSdtvgrsavfcaaattinkcktegvidvfqvlksqRiqkpgsvqtvqqyqgifqiv
EMYLAINSTYS
|| .|||
ltyldsfetys
|
|||||||||
subfamily_CG7180_pd | Subfamily CG7180 | 1300-1487 | 1.8e-34 | 113.7 | In-house | 31-233 (296) | alignment | ||
Range on Protein: 1300-1487
Range on HMM: 31-233/296.0
DKQCSVGLNGMNKPLNRFRNIVPYDDNIITL-KLPGVAQHEYINASYIHGYSKARKFIAAQGPMKKTLVDFWCLIWQEKPASVVMLTNLVEDSKtKCEQY
.| ||. |. || ..|||| | . | || | .. .||||.|. .. | ...| ..|.|.|. .|| |...|. .||.||. . .| .. .|
igdCagglrkenreknrdvkvvPyDynRvvLekldGeeksdYinavyvdsflkkkeyivteapkketvdefWrlvydeeisavvvLtktfdfak.mypsy
WPQCLneIEQFGPFSVTLLEDYVMPDYVIRNISVTLQ---------DGSGEVHALTQYHLTTWPD-HGVPEYATPLMTLHKRVMSSS-------AKGPIL
||. ||.|.. | ..| ... .||.. .| . . . |. .....||.|. . || .. |. | .|| . .||..
wpnks..keqygeifveiveekqyanlkirtfkltkkivalteqekqvkaetRivklfqlteWeledkvPlstnalielrrrvrlwrekvdedpeegPvv
VHCSAG
|..| |
vvssdG
|
|||||||||
subfamily_PTPN14_pd | Subfamily PTPN14 | 1299-1487 | 2.5e-34 | 113.6 | In-house | 37-239 (300) | alignment | ||
Range on Protein: 1299-1487
Range on HMM: 37-239/300.0
NDKQCSVGLNGMNKPLNRFRNIVPYDDNIITLKLPGVAQHEYINASYIHG--YSKARKFIAAQGPMKKTLVDFWCLIWQEKPASVVMLTNLVEDSKTKCE
.| ..|.. . |.. |||....||.|| . |. ....||||| |. .| |..|.||||...|. ||| ..|... . .||||. || |.|.
edallstaklpenaeknrfkdvlPyednrvelsptkenstgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivmlteeeedgkeksf
QYWPQC--LNEIEQFGPFSVTLLEDYVMPDYVIRNISVTLQdGSGEVHALTQYHLTTWPDHGVPEYATPLMTLHKRV-------MSS----SAKGPILVH
.|.|.. .. .|| | || . .. . . . |.| . | |||||||| .. . ..| |. ..| |.|||
kyfPkleskkktvefgkfkvttkfsedsdsvittglklkhl.pskeertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseveskeskPPvlvh
CSAG
||||
CsaG
|
|||||||||
subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 1284-1487 | 2.8e-34 | 113.2 | In-house | 18-179 (392) | alignment | ||
Range on Protein: 1284-1487
Range on HMM: 18-179/392.0
SNAYFSEQFKDLYSGNDKQCSVGLNGMNKPLNRFRNIVPYDDNIITL-KLPGVAQHEYINASYIHGYSKARKFIAAQGPMKKTLVDFWCLIWQEKPASVV
.| |.|.|.|| . . . .|. . .|.. ||..||.||| . . | . .....|.|||||... . .||.||| .| ||| ...||......
hsalffeefhdlpgpdiypqtvaqkeinlkknryknilpydsarvkleviddipdsdylnasyipsfdnekayiasqgpnaaslddfwrmvfqenvttia
MLTNLVEDSktkceqywpqclneieqfgpfsvtlledyvmpdyvirnisvtlqdGSGEVHALTQYHLTTWPDHGVPEYATPLMTLHKRVMSSS--AKGPI
|.|.| | .... .|.|.| |||..||.... |. . | | . |.
mvtklkegd.............................................kgddartvaqfhftewPdkdvpkhtssllkfikevkadfGqythpl
LVHCSAG
..|||||
iihcsag
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 1314-1588 | 7e-34 | 112.0 | In-house | 36-290 (297) | alignment | ||
Range on Protein: 1314-1588
Range on HMM: 36-290/297.0
LNRFRNIVPYDDNIITLKlPGVAQHEYINASYIHGY--SKARKFIAAQGPMKKTLVDFWCLIWQEKPASVVMLTNLVEDSKTKCEQYWPQCLNEIEQFGP
||.|.|. .||. . |. ......|||| |. . |.| ||||...|. ||| |.... .||...| || . || |||.. .| . |
knryrdilatddtrvkll.rviterdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrdkcapywpsvvqerlkagd
FSVTLLEDYVMPdYVIRN-ISVTLQDGsGEVHALTQYHLTTWPDHGVPEYATPLMTLHKRVMSSSAKGPILVhcsagwNIVQ-FQVIgwmndgVlrdprt
. | | .. . ..| | .. .||||||| | .. .| | |... .|. | .. |
vvveflsstsde.fdrviltelqliyr.sesrvvrhvqflswpdhGvpsdledlvrfqaqvcscciavpmml......alvemftam......v......
VLQVIDdviHRQQKIGGGPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQYITIYEA
.||. | .. ...|||| | |.|| . |.. . . . || . . |. .. | ||||. .|.|
flqles...lraemprnayllvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqtleqfellyda
|
|||||||||
subfamily_PTPRN_pd | Subfamily PTPRN | 1296-1487 | 1.1e-33 | 111.2 | In-house | 41-234 (297) | alignment | ||
Range on Protein: 1296-1487
Range on HMM: 41-234/297.0
YSGNDKQCSVGLNGMNKPLNRFRNIVPYDDNIITLKLPGVA-QHEYINASYIHGY-SKARKFIAAQGPMKKTLVDFWCLIWQEKPASVVMLTNLVEDSKT
| ... ..|. . | || ....|||.....|| | ...||||| | .| .||.|||. .|. ||| ..|.. . .|.||.| |.. .
yeaepstkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplastvadfwqmvweqGvvvivnltrleeegvk
KCEQYWPQCLNEIeqFGPFSVTLLEDYVM-PDYVIRNISVTLQDgSGEVHALTQYHLTTWPDHGVPEYATPLMTLHKRVMSSS--AKGPILVHCSAG
.|..|||. .|. .. . | |. ... ||..| . . . . | ..||.| .||..||| | .|. . ..| | ||.||||.|
qckrywpdeGsev..yhiyevhlvsehiwcddylvrsfylknlq.tsetrtvtqfhflswpeegvPasaksllefrrkvnksyrGrscpivvhcsdG
|
|||||||||
subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 1489-1602 | 1.7e-33 | 110.8 | In-house | 174-287 (287) | alignment | ||
Range on Protein: 1489-1602
Range on HMM: 174-287/287.0
NIVQFQVIGWMNDGVLRDPRTVLQVIDDVIHRQQKIGGGPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQYITIYEA
...|.|. | . | . .|.|.| ||.. .. |.| | ..||||||||| |....||. .....|| |||.||||| | . |||.| | |||. |...
qvkqyqitnWdstgkvtepqtillvieemyktqrkrgntsivvhCsdtvGrsamfcaaattinkckteGviDvfqvlksqriqkpgsvqtveqykfindi
LEMYLAINSTYSNF
. .|| .|||.|
vleyldsfetysdf
|
|||||||||
subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 1315-1487 | 2.1e-33 | 110.2 | In-house | 60-226 (290) | alignment | ||
Range on Protein: 1315-1487
Range on HMM: 60-226/290.0
NRFRNIVPYDDNIITLKlpGVAQHEYINASYIHGYSKarKFIAAQGPMKKTLVDFWCLIWQEKPASVVMLTNLVEDSKTKCEQYWPQCLNEIEQFGPFSV
||....| | . || . .|. | |..| || .||..|.| .|.| .. ||| | .||| .|.|| |.|||||.|. |. || ..|
nrykdvvcndktrvilk..dGydGdyvhanyvkGlka..mfiltqGalkdtvidiwrmvlqekvaaivmlceliedGkakceqyypekeGevltfGeitv
TLLEDYVMPDYVIRNISVTLQDGSGEVHALTQYHLTTWPDHGVPEYATPLMTLHKRVmsSSAKGPILVHCSAG
. |. . .|... . || | | ... .|||. |. . |. . . . | ||. ||||||
lcseeddkdaniikktlsvrdkdsGkehklkhlkikswpdksvalstlallrtlril..rkasGpvvvhcsaG
|
|||||||||
0051429 | (Phosphotyrosine protein) phosphatases II | 1339-1488 | 4.6e-33 | 110.4 | In-house | 5-161 (272) | alignment | ||
Range on Protein: 1339-1488
Range on HMM: 5-161/272.0
EYINASYIHGYSK---ARKFIAAQGPMKKTLVDFWCLiWQEKPASVVMLTNLVEDSKTKCEQYWP----------QCLNEIEQFGPFSVTLLEDYVMPDY
||||... || . .......||.. | ||| | .... ..|.|....| . ||..||| . .| ..||||. ....||
gyiNardvggygrvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseellldy
VIRNISVTLQDGSGEVHALTQYHLTTWPDHGVPEYAtpLMTLHKRVMSssaKGPILVHCSAGW
..|.. .||. . ||.. ....| | |||||||. | | .| . . . .||.|||||||.
ilrellltlllsagearevmhlhytdwpdhgvpqea..llellellld...ggpvlvHCsaGk
|
|||||||||
subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 1291-1487 | 9.7e-32 | 105.2 | In-house | 21-219 (307) | alignment | ||
Range on Protein: 1291-1487
Range on HMM: 21-219/307.0
QFKDLYSGNDKQCSVGLNGMNKPLNRFRNIVPYDDNIITLKLPGVAQhEYINASYIHGYSKARKFIAAQGPMKKTLVDFWCLIWQEKPASVVMLTNLVED
.|. | . . .| | ||.... | . | .|..|.| .|| | |. | .|||.||||...| .||... ||| ||.|| ...|
efrvlakktpegvtveafsantdknryqdvkcqdkgrivvkfdglas.dyihanylgiaikpkkficaqgplentqysfwamaiqekvesvimlckviel
SKTKCEQYWPQCLNEIEQFGPF----SVTLL-EDYVMPDYVIRNISVTLQDGSGEVHALTQYHLTTWPDHGVPEYATPLMTLHKRVMssSAKGPILVHCS
.| ||||||| . || ||. | . . || . |.. | ... ..... . |||.|||. . | . | . |..||||
akikceqywpleegqklvfgeapntisvanlgakklapdedlinvttlkvdwaqksrtiqhlqwenwpdrgvpqinltainlleavr..ydtnpvvvhcs
AG
||
aG
|
|||||||||
subfamily_ptpA1_pd | Subfamily ptpA1 | 1269-1487 | 2.8e-31 | 103.7 | In-house | 9-239 (418) | alignment | ||
Range on Protein: 1269-1487
Range on HMM: 9-239/418.0
SLNDLGNHVACCHSdsnayFSEQFKDLY-SGNDKQCSVGLNGMNKPLNRFRNIVPYDDNIITLK-LPGVAQHEYINASYIHGySKARKFIAAQGPMKKTL
|. .| ||. | | |.|. | | . | | . | ||. ||.| . . || . .|||| || | . ..||..|||. .|.
siynlknhikcihk.....ikeefrlleesvgpsetsegdkkhntsknrytnilpvnhtrvqlkkiqdkegsdyinanyidg.aypkqfictqgplpnti
VDFWCLIWQEKPASVVMLTNLVEDSKTKCEQYWPQCL---------NEIEQFGPFSVTLLEDYVMPDY--VIRNISVTLQdgsGEVHALTQYHLTTWPDH
||| ..|... .|||. |. . ||..|||. . | | || .|| |.| |. . ||| .|.. || . .|||. ||||
adfwrmvwenrcriivmlsresencrikcdrywpeqiggeqfsiygngnevfgtysvelveviqdpereiitrnirltfe...getrditqyqyegwpdh
GVPEYATPLMTLHK-------R-VMSSSAKGPILVHCSAG
.|... |. | . . . || . ||.||||||
nipdhtqpfrqllhsitnrqnqiipssdrnvpiivhcsag
|
|||||||||
subfamily_PTPRD_pd | Subfamily PTPRD | 1490-1599 | 1.6e-30 | 101.3 | In-house | 179-287 (564) | alignment | ||
Range on Protein: 1490-1599
Range on HMM: 179-287/564.0
IVQFQVIGWMNDGVLRDPRTVLQVIDDVIHRQqKIGGGPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQYITIYEAL
. ||. . | . || ....|..|..| . . . . |||||||| | |||....|.. ||. |.|..||..|. |||.. .. | | |||| |.||.
VrqFhFtsWPdhgvpesatslLdlirkvraln.epdagPivVhCSaGVGRTGtfividamlerikeektvDiyqyvkalrkqRnamVqteeQYiFiheai
EMYLAINSTY
.|| .|
lealacgnte
|
|||||||||
0041856 | (Phosphotyrosine protein) phosphatases II | 1311-1488 | 2.3e-30 | 100.9 | In-house | 1-120 (182) | alignment | ||
Range on Protein: 1311-1488
Range on HMM: 1-120/182.0
NKPLNRFRNIVPYDDNIitlklpgvaQHEYINASYIHGYSKARKFIAAQGPMKKTLVDFWCLIWQEKPASVVMLTnlvedsktkCEQYWPqclneieqfg
|...||...|.||| .. ||||... |. .|..|||.|||...|. ||. ...... ..|.|| .|.|||
nldknrysdilpydhsr.........dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt.........eelywp..........
pfsvtlledyvmpdyvirnisvtlqdgSGEVHALTQYHLTTWPDHGVPEyATPLMTLHKRVMSssAKGPILVHCSAGW
. . .. .||. . |||||||. | . ..| . .||.|||||||
...........................ellerlgiqylylpwpDhgvpd.ldelldfieevle..eggpvlVHCsaGv
|
|||||||||
subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 1489-1599 | 3.4e-30 | 100.3 | In-house | 186-296 (298) | alignment | ||
Range on Protein: 1489-1599
Range on HMM: 186-296/298.0
NIVQFQVIGWMNDGVLRDPRTVLQVIDDVIHRQQKIGGGPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQYITIYEA
...|.... | . || . ..||.....| ||. | |..|.||. | |.| ..||. ||. |.| ||||||| |.|....||||.| |||. ||||
evrqlhftsWpdkgvpenatsvldllrkvrasqqqagnkpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyea
LEMYLAINSTY
.|. ...
vlealdsfnde
|
|||||||||
subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 1489-1598 | 3.4e-29 | 96.9 | In-house | 179-288 (319) | alignment | ||
Range on Protein: 1489-1598
Range on HMM: 179-288/319.0
NIVQFQVIGWMNDGVLRDPRTVLQVIDDVIHRQQKIGGGPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQYITIYEA
....|| | ...| .. ...|... .. . ..| ||||||||. | ||| .......||. | |||.|||.. . |. .. | . |||. ||||
evkhfqyteWpdhdvPekatslldllkrirksrektqsgPivvhCsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyea
LEMYLAINST
| .. . .|
lleaveagdt
|
|||||||||
subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 1490-1600 | 1.1e-28 | 95.1 | In-house | 139-249 (250) | alignment | ||
Range on Protein: 1490-1600
Range on HMM: 139-249/250.0
IVQFQVIGWMNDGVLRDPRTVLQVIDDVIHRQQKIGGGPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQYITIYEAL
..|.. . | . || . ..||.....| ||..| .|..|.|| |.|.| ..||. ||. | | |||||.| |.|.. .|.||..||||. .||..
vrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidavlerlkkekvvdvfkvikvlrkdrphavesleqyvfvyeii
EMYLAINSTYS
.| . |.
lkaldsvedya
|
|||||||||
subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 1301-1488 | 1.5e-28 | 94.2 | In-house | 27-211 (281) | alignment | ||
Range on Protein: 1301-1488
Range on HMM: 27-211/281.0
KQCSVGLNGMNKPLNRFRNIVPYDDNIITLKL--PGVAQHEYINASYIHGYSKARKFIAAQGPMKKTLVDFWCLIWQEKPASVVMLTNLVEDSKTKCEQY
|.| . .|. ||. || | . ||. | .|| | ||. | .| .||| |.| ||| .||||. ...||| ...| . || .|
dlctvfnqpvnnkknrylnipcldisrvqlkvkmpnknstdyihanyirspflkrgyiltqgpkketradfwrmiwqenttaivmlcqfletnrekcaey
WPQCLNEIEQFGPFSVTLLEDYVMPDYVIRNISVTLqdgSGEVHALTQYHLTTWPDHGVPEYATPLMTLHKRVMSSSAkgPILVHCSAGW
.|. || .||. . | | . .. || . .|.. ||| ||| . .. . ... . |. | ..|||||
fprnahcclqfdklsvsyedstvnkslvttrlnlsy...egetrlithwlwkewpdwqvpessevmlkilrkirarst..ppvihcsagv
|
|||||||||
subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 1314-1487 | 1.7e-28 | 94.3 | In-house | 51-229 (305) | alignment | ||
Range on Protein: 1314-1487
Range on HMM: 51-229/305.0
LNRFRNIVPYDDNIItlKLPGVAQHEYINASYIHGYSKARKFIAAQGPMKKTLVDFWCLIWQEKPASVVMLTNLVEDSKTKCEQYWPQCLNEIEQFGP--
||.... |.| . || | |||| | |. .....|| .| |..|| ||| . .|.| .. || ||.| || .|.. ... .|
knrykdvgcldnnrv..klegpwpheyihanyvstptnpkrfictqaplektcadfwymclqdkveaifmlcnllekgakkcleyfaskdkdvlefeekg
--FSVTLL----EDYV-MPDYVIRNISVTLQDGSGEVHALTQYHLTTWPDHGVPEYATPLMTLHKRVmsSSAKGPILVHCSAG
|| . ... . .... .... .... |.|| ||| ||| . .. | .. ..|||| ||||||
qkisvkfessvtlkfrkdakakvtetvlviegpgekarkvthyhwidwpdrgvpaadlailelleka..rpskgpivvhcsag
|
|||||||||
subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 1490-1600 | 2e-28 | 94.4 | In-house | 177-287 (318) | alignment | ||
Range on Protein: 1490-1600
Range on HMM: 177-287/318.0
IVQFQVIGWMNDGVLRDPRTVLQVIDDVIHRQQKIGGGPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQYITIYEAL
. |... | . ||. .. ..|... .| . ||| | |||||||| | ||||..|..| ||. |||..|||||. | |.. .. | | .||. ||..|
vrqyhytsWpdegvpesgaslldlvrqvskaqqksgagpivvhCsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqtedqyefiydvl
EMYLAINSTYS
.|| |.
lealasgdtev
|
|||||||||
0046845 | (Phosphotyrosine protein) phosphatases II | 1490-1601 | 3.2e-27 | 91.1 | In-house | 167-282 (284) | alignment | ||
Range on Protein: 1490-1601
Range on HMM: 167-282/284.0
IVQFQVIGWMNDGVLRDPRTVLQVIDDVIHRQQK-IGGGPIVVHCSDTVSRTGVYCAISIALEQCKAEG---VVDVFQVTKALKRSKPGAVTTLEQYITI
. .|....| ..|| .|. .|. ...| . ... ||||||||||. |.|||...|. ..||| ..|| .|||... | |.. .||.|.|||||. .
vthfhytswpdhgvppspedlleflrlvrellenlpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfv
YEALEMYLAINSTYSN
|||| .|| |. .
yealleylklkltlle
|
|||||||||
subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 1302-1489 | 3.6e-27 | 90.1 | In-house | 26-215 (285) | alignment | ||
Range on Protein: 1302-1489
Range on HMM: 26-215/285.0
QCSVGLNGMNKPLNRFRNIVPYDDNIITLKlpgVAQHEYINASYIHGYSKAR-KFIAAQGPMKKTLVDFWCLIWQEKPASVVMLTNLVEDSKTKCEQYWP
.|. | |||. .. .. . || ...|| ||... | . .|..|||. .|| ||| .|.||| | |.|| |.| || |.|
nctytayeanpdlnryadvrcieetrvvlk...nhdrdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyyp
QCLNEIEQFGPFSVTLLE--DYVMPDYVIRNISVT-LQDGSGEVHALTQYHLTTWPDHGVPEYATPLMTLHKRVMSSSAK-GPILVHCSAGWN
. | |. .|| . .|| | . . .. ...|. .| | | . . .. |||. || | |.. |.| | | || ||||||
eklgevvkfgkyeitlteckeeaiagtilnaltvintedasseplymnhvqvpwwpdqlapedarpmielykwvkkvnpkekpicvhcsagvg
|
|||||||||
0050432 | (Phosphotyrosine protein) phosphatases II | 1490-1599 | 7.8e-27 | 89.8 | In-house | 199-305 (308) | alignment | ||
Range on Protein: 1490-1599
Range on HMM: 199-305/308.0
IVQFQVIGWMNDGVLRDPRTVLQVIDDVIHRQqkiGGGPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQYITIYEAL
. .|. ..| ..|| .|. .|. .. | ... .|||||||||. |.|||...|. ..||| ..|| ||||.. | |.. .||.|.|.|||. .|.||
vthfhytnWpdhgvPpspeilldflelvrksl...pggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylflyral
EMYLAINSTY
.|| |.
leylklkltk
|
|||||||||
0036941 | (Phosphotyrosine protein) phosphatases II | 1490-1598 | 1.3e-26 | 89.1 | In-house | 170-282 (297) | alignment | ||
Range on Protein: 1490-1598
Range on HMM: 170-282/297.0
IVQFQVIGWMNDGVLRDPRTVLQVIDDVIHRQQKI-GGGPIVVHCSDTVSRTGVYCAISIALEQCK---AEGVVDVFQVTKALKRSKPGAVTTLEQYITI
. .|...|| .|| .|...|. |. | ...... .|||..||||. |.|.|...|. ..|.| . || ||.... | |.. .||||.|||||. .
vthfhytgwpdhgvpespaslldfielvrkvlkllpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrfl
YEALEMYLAINST
|||| ..| . |
yeallellkkklt
|
|||||||||
subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 1291-1491 | 1.4e-26 | 87.8 | In-house | 32-237 (310) | alignment | ||
Range on Protein: 1291-1491
Range on HMM: 32-237/310.0
QFKDLYSGNDKQCSVGLNGMNKPLNRFRNIVPYDDNIITLKLPGVAQHEYINASYIHGYSKARKFIAAQGPMKKTLVDFWCLIWQEKPASVVMLTNLVED
|.. | . .| . . ||. ..| |. . ||. ..|| | |.. || .|||...|..||| .|.||. |...| . .|.
qyrkldakqdssltyeaykkymhknrysdvvcldtsrvklkidksryedyihanyvktnylrstficsqgplqhtiidfwrmifqeraesilllckvgee
SKTKCEQYWPqCLNEIEQFGPFSVTLLEDYvMPDYVIRNISVTLQDG---------SGEVHALTQYHLTTWPDHGVPEYATplMTLHKRVMSSSAKGPIL
. || ||| | | .| || | . .. | |..||. . .. . ||| |||. |. .|... .|| .
grpkcvgywp.slgvtetygcirvtnlses.seefeicnlavtfvpdnvpvdeqpanlkelrvslikwpnwpdrgvpdekc..htvpqrllaqvrhgpcv
VHCSAGWNIV
|||||| . .
vhcsagkdrl
|
|||||||||
0051299 | (Phosphotyrosine protein) phosphatases II | 1490-1593 | 2.3e-26 | 88.4 | In-house | 184-286 (288) | alignment | ||
Range on Protein: 1490-1593
Range on HMM: 184-286/288.0
IVQFQVIGWMNDGVLRDPRTVLQVIDDVIHRQQkIGGGPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQYITIYEAL
. .|....| ..|| .|. .|. . .|.. .. ||||.|||||. |.|||...|. ..||| ..||.|||... | |.. .||.|.|.|||. .||||
vthfhytnwpdhgvpdspellldflrlvrkala.sgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyeal
EMYL
.||
leyl
|
|||||||||
0036282 | (Phosphotyrosine protein) phosphatases II | 1339-1489 | 2.6e-26 | 87.8 | In-house | 3-116 (174) | alignment | ||
Range on Protein: 1339-1489
Range on HMM: 3-116/174.0
EYINASYIHGYSKARKFIAAQGPMKktlvdFWCLIWQEKPASVVMLTNLVEDSKTKCEQYWPQclneieqfgpfsvtlledyvmpdyvirnisvtlqDGS
|||||..... ...|| |||.. || ...... .||||....|. ..|| .||| . .
dyinaspldlsyitprliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe..................................lre
GEVHALTQYHLTTWPDHGVPEYATpLMTLHKRVMSS---SAKGPILVHCSAGWN
... ||. . |||||||. .. | .. |.| . . .||.||||||| .
dlerlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsaGvg
|
|||||||||
0047943 | (Phosphotyrosine protein) phosphatases II | 1490-1593 | 1.7e-25 | 85.5 | In-house | 168-272 (273) | alignment | ||
Range on Protein: 1490-1593
Range on HMM: 168-272/273.0
IVQFQVIGWMNDGVLRDPRTVLQVIDDVIHRQQKI-GGGPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQYITIYEA
. .|.. || ..|| .. .|. |..| . .... ..||.|||||. |.|||...|. ..|.| ..|| |||... | |.. .||.|.|.|||. .|||
vthfhytgwpdhgvppslesllefielvrkalealpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyea
LEMYL
| .||
lleyl
|
|||||||||
0039614 | (Phosphotyrosine protein) phosphatases II | 1490-1596 | 2.1e-25 | 85.2 | In-house | 185-292 (297) | alignment | ||
Range on Protein: 1490-1596
Range on HMM: 185-292/297.0
IVQFQVIGWMNDGVLRDPRTVLQVIDDVIHRQQKI-GGGPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQYITIYEA
. .||..|| .|| .....|.... | ..... .|||..||||. |.|||...|. ..|||.. || |||... | |.. .||||.|..||. .|.|
vthfqytgwpdhgvppslellleflelvrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflyda
LEMYLAIN
| ..| .
llellkrk
|
|||||||||
0040438 | (Phosphotyrosine protein) phosphatases II | 1490-1599 | 3.4e-25 | 84.4 | In-house | 174-282 (317) | alignment | ||
Range on Protein: 1490-1599
Range on HMM: 174-282/317.0
IVQFQVIGWMNDGVLRDPRTVLQVIDDVIHRQQkiG-GGPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQYITIYEA
. .|. .|| .|| .|...|. .. | . .. . |||..||||. |.|||...|. ..|||.. || |||... | |.. .||||.|.|||. .|.|
vthfhytgWpdhgvppspdllldfleavreale..dpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflyda
LEMYLAINSTY
| .|| . |.
lleylkrkltl
|
|||||||||
subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 1297-1487 | 3.9e-25 | 83.4 | In-house | 19-202 (267) | alignment | ||
Range on Protein: 1297-1487
Range on HMM: 19-202/267.0
SGNDKQCSVGLNGMNKPLNRFRNIVPYDDNIITLKlpgVAQHEYINASYIHGYSKARKFIAAQGPMKKTLVDFWCLIWQEKPASVVMLTNLVEDsktKCE
| . ..| . |. ||. . .||||... |. ..|||||||..|| . ..||. |.|.|.| ||. .| ..| . .|.||. .| .
sdtsstisqsiaeknqernrlddnlpyddtrvilr...tkeeeyinasyvegyktknafivtqdplkntitdfltvihdqkvpvivlltkvftd...nir
QYWPQCLNEIEQFGPFSVTLLEDYVMPDYVIRNISVTLQDGSgeVHALTQYHLTTWPDH-GVPEYATPLMTLHKRVMSSSAKGPILVHCSAG
..|| . . ... ..| . || | . . ... | | .| |. | | ||. . . . |..|.||.|
lfwPPkmgqakkyqdltvehslekeendyqiitlelkfknes..ahnvtlyyykkwnintnnkpylkplfgilaknqlengnrPlvvacsdG
|
|||||||||
DSPc_SM00195 | 1490-1593 | 5.2e-25 | 83.6 | In-house | 160-262 (263) | alignment | |||
Range on Protein: 1490-1593
Range on HMM: 160-262/263.0
IVQFQVIGWMNDGVLRDPRTVLQVIDDVIHRQQKIgGGPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQYITIYEAL
. |.|. .| . || ... ||... | ...... ||||||||. |.|||....|.|.|.....| ||.|.. |.|. ..||.|.|||||..||||.
vtqyqyknWpdhgvpdstksvlellravkksksts.sgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeai
EMYL
|.
leyi
|
|||||||||
PTPc_SM00194 | 1490-1593 | 5.2e-25 | 83.6 | In-house | 160-262 (263) | alignment | |||
Range on Protein: 1490-1593
Range on HMM: 160-262/263.0
IVQFQVIGWMNDGVLRDPRTVLQVIDDVIHRQQKIgGGPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQYITIYEAL
. |.|. .| . || ... ||... | ...... ||||||||. |.|||....|.|.|.....| ||.|.. |.|. ..||.|.|||||..||||.
vtqyqyknWpdhgvpdstksvlellravkksksts.sgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeai
EMYL
|.
leyi
|
|||||||||
subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 1341-1507 | 6.8e-25 | 82.4 | In-house | 78-245 (301) | alignment | ||
Range on Protein: 1341-1507
Range on HMM: 78-245/301.0
INASYIHGYSKARKFIAAQGPMKKTLVDFWCLIWQEKPASVVMLTNLVEDSKTKCEQYWPQCLNEIEQFGPFSVTLLE-DYVMPDYVIrNISVTLQDGSG
| | .| ....|||.|||.|.| ||| .. | . .|||.. ||. ..|||.| |. .| . | |.... . .... . .. . .. ..| .|
ihanwiptsGhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkisekldigrfkikiknkelilnkkis.krtlevedstg
EV--HALTQYHLTTWPDHGVPEYATPLMTLHKRVMSSsaKGPILVHCSAGWN-IVQFQVIGWMNDGVLRDP
.. ...| | ..|.|.|||. . |. | . | | . ||.|||||| | | .. |. ||
kfatrtvthyqysewtdrgvPkshaelfdlmelvkks..ekPivvhcsaGiGrsvafigteylareveadp
|
|||||||||
subfamily_PTPRA_pd | Subfamily PTPRA | 1490-1593 | 7.8e-25 | 82.4 | In-house | 193-295 (330) | alignment | ||
Range on Protein: 1490-1593
Range on HMM: 193-295/330.0
IVQFQVIGWMNDGVLRDPRTVLQVIDDVIHRQQKIGGgPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQYITIYEAL
. || .| . || .|. .|... | . .|. .| ||||||| | ||| ..... ||. |||..||||.. | |. .| | |.||| ||..|
vrqfhftswPdvGvPfepiGmlkllkkvkklnqqsag.pivvhcsaGvGrtGtfivldavlervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvl
EMYL
|
leyy
|
|||||||||
0043336 | (Phosphotyrosine protein) phosphatases II | 1490-1592 | 1.2e-24 | 82.7 | In-house | 175-276 (278) | alignment | ||
Range on Protein: 1490-1592
Range on HMM: 175-276/278.0
IVQFQVIGWMNDGVLRDPRTVLQVIDDVIHRQQkIGGGPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQYITIYEAL
..... .||. .|| .. ..|. . .|..... .||..||||. |.|||...|. ..||| . || ||.... | |.. .||||.|..||. .||||
vthyhylgwpdhgvpeslsllldflkavreale.dsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyeal
EMY
.|
ley
|
|||||||||
0045450 | (Phosphotyrosine protein) phosphatases II | 1490-1593 | 1.3e-24 | 83.0 | In-house | 197-304 (307) | alignment | ||
Range on Protein: 1490-1593
Range on HMM: 197-304/307.0
IVQFQVIGWMNDGVLRDPRTVLQVIDDVIHRQQKI-GGGPIVVHCSDTVSRTGVYCAISIALEQCKAEGV---VDVFQVTKALKRSKPGAVTTLEQYITI
. .|. .|| ..|| .. ..|. |. | . ... .|||..||||. |.|||...|. ..|.| ..||. ||.... | |.. .||||...|||. .
vthfhytgwpdhgvppsfeelldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrfl
YEALEMYL
|||| ..|
yeallell
|
|||||||||
0043147 | (Phosphotyrosine protein) phosphatases II | 1338-1489 | 1.9e-24 | 81.8 | In-house | 5-112 (172) | alignment | ||
Range on Protein: 1338-1489
Range on HMM: 5-112/172.0
HEYINASYIHGYSKARKFIAAQGPMKKTLVDFWCLIWQEKPASVVMLTNLvedsktkceqywpqclneieqfgpfsvtlledyvmpdyvirnisvtLQDG
. ||||||...| . ..||| |||. || ||| ...... .|.||.| | |.
sdyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltel..............................................lydp
SGEVHALTQYHLTTWPDHGVPeYATPLMTLHKRVMS---SSAKGPILVHCSAGWN
..... ||. . ||||||| . |. . . . . | .||.|||||||..
ellerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvg
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 1491-1589 | 3.2e-24 | 81.0 | Pfam-A | 136-233 (235) | alignment | ||
Range on Protein: 1491-1589
Range on HMM: 136-233/235.0
VQFQVIGWMNDGVLRDPRTVLQVIDDVIHRQqKIGGGPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQYITIYEAL
|... .| . || ..|. .|..|..| ... . ||.|||||. |.|||...|..|.|||..||. |||.|. | |....||.|..||||| .|.|.
kqlhytnWpdhgvpespkslldlirkveksk.eaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmvqsleqYiflykai
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 1491-1589 | 3.2e-24 | 81.0 | In-house | 136-233 (235) | alignment | ||
Range on Protein: 1491-1589
Range on HMM: 136-233/235.0
VQFQVIGWMNDGVLRDPRTVLQVIDDVIHRQqKIGGGPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQYITIYEAL
|... .| . || ..|. .|..|..| ... . ||.|||||. |.|||...|..|.|||..||. |||.|. | |....||.|..||||| .|.|.
kqlhytnWpdhgvpespkslldlirkveksk.eaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmvqsleqYiflykai
|
|||||||||
0040439 | (Phosphotyrosine protein) phosphatases II | 1490-1593 | 4.3e-24 | 80.9 | In-house | 142-246 (249) | alignment | ||
Range on Protein: 1490-1593
Range on HMM: 142-246/249.0
IVQFQVIGWMNDGVLRDPRTVLQVIDDVIHRQQKI-GGGPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQYITIYEA
. ..|...| .|| .. ..|. |. | . .... |||..||||. |.|||...|. ..||| . |. ||.... | |.. .||||...|||. .|||
vlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdleeavkllrsqRpgavqnpeqyrflyea
LEMYL
| ..|
llell
|
|||||||||
subfamily_PTPRK_pd | Subfamily PTPRK | 1490-1593 | 4.4e-24 | 79.9 | In-house | 175-278 (314) | alignment | ||
Range on Protein: 1490-1593
Range on HMM: 175-278/314.0
IVQFQVIGWMNDGVLRDPRTVLQVIDDVIHRQQKiGGGPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQYITIYEA-
. ||| .|| . .| ...|... | . |.. . |.|||||| |||...||.| |. . |||||||.. |.|. .|. | | |||. ||..
vrqfqflgWpdhdvPvsatgllklvrrvkksqee.eaGrivvhCsaGaGrtGtfiaidivldmieregvvdvfnavktlrsrkvnmveteeqykfiydvi
LEMYL
|| |
leacl
|
|||||||||
0046846 | (Phosphotyrosine protein) phosphatases II | 1339-1488 | 4.7e-24 | 80.5 | In-house | 13-120 (176) | alignment | ||
Range on Protein: 1339-1488
Range on HMM: 13-120/176.0
EYINASYIHGYskarKFIAAQGPMKKTLVDFWCLIWQEKPASVVMLTNLVEDSKTKCEQYWPQclneI----Eqfgpfsvtlledyvmpdyvirnisvtl
||||..| |. ..|| |||. .|| ||. ...... ||.||..|| .. || .|||. .
dyinanlilgs....rpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpe....leklgi...........................
qdgsgevhaltQYHLTTWPDHGVPEYaTPLMTLHKRVMSSSAKG-PILVHCSAGW
||. . |||||||.. . |..| . . . .| |.|||||||
...........qylhlpwpDhgvpdl.elllellefirealkeggpvlVHCsaGi
|
|||||||||
subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 1311-1488 | 5.1e-24 | 79.4 | In-house | 55-232 (305) | alignment | ||
Range on Protein: 1311-1488
Range on HMM: 55-232/305.0
NKPLNRFRNIVPYDDNIITLKLPGvaQHEYINASYIHGY-SKARKFIAAQGPMKKTLVDFWCLIWQEKPASVVMLTNLVEDSKTKCEQYWPQCLNEIEQF
.. ||.... | ... |. | .|| | |. ..||.||||. .|. .|| .. |.| .||| . || | || |||| . | ..
aitknryqdvpcqdqsavkldkps..psdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkveqivmlcktvelgklkcaqywpaaqgeklel
GPFSVTLLEDYVMP---DYVIRNISVTLQDGSGEVHALTQYHLTTWPDHGVPEYATPLMTLHKRVmsSSAKGPILVHCSAGW
| | | |. . | .. .. . . | ||| ||| . | . .| ||.||||||
ksgivvenvsgskpmerdaeiqitllnltysgdqkmsvrhlqwtewpdrgvppckltslellsai..rgskvpivvhcsagi
|
|||||||||
0049260 | (Phosphotyrosine protein) phosphatases II | 1345-1489 | 5.9e-24 | 79.9 | In-house | 1-101 (152) | alignment | ||
Range on Protein: 1345-1489
Range on HMM: 1-101/152.0
YIHGYSKARKFIAAQGPMKKTLVDFWCLIWQEKPASVVMLTNLVEDSKTKCEQYWpqclneieqfgpfsvtlledyvmpdyvirnisvtlqdgsgevhal
.|.|| . ..|||.|||. || ||| .... . .||||.|.|. | |||||.
fidgyampfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi.............................................
tQYHLTTWPDHGVPEYATPLMTLHKRVMS--SSAKGPILVHCSAGWN
||. . |||||||. . |. |.. . . .||.||||||| .
.qylhlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvg
|
|||||||||
PTPc_DSPc_SM00012 | 1490-1589 | 9.2e-24 | 79.0 | In-house | 2-103 (105) | alignment | |||
Range on Protein: 1490-1589
Range on HMM: 2-103/105.0
IVQFQVIGWMNDGVLRDPRTVLQVIDDVIHRQQKIG-GGPIVVHCSDTVSRTGVYCAISIALEQCKAE-GVVDVFQVTKALKRSKPGAVTTLEQYITIYE
. .... || . || ... .|.....| . ..|.. ..|.|||||. |.|||...|..|.|.|...| . ||.||. |.|....||.|.|.|||. .|.
vkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylflyr
AL
||
al
|
|||||||||
0049772 | (Phosphotyrosine protein) phosphatases II | 1305-1489 | 1.1e-23 | 79.9 | In-house | 40-224 (314) | alignment | ||
Range on Protein: 1305-1489
Range on HMM: 40-224/314.0
VGLNGMNKPLNRFRNIVPYDdNIITLKLPGVAQHEYINASYIHGYskaRKFIAAQGPMKKTLVDF----------WCLI--WQEKPASVVM---------
|. .|. ||. .|.|.| | |. .| . ||||||..|. .||||.|||.. |.||| | .. .. .. .||
vadlflnrdknryldilpad.nrvilpglpvsgsdyinasyvdgf...lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivmsrdevlade
------------LTNLVEDSktkceQ-YWPQCLNEIEqfgpfsvtllE-----DYVmpdyvirnisvtlqdgsgeVHALTQYHLTTWPDHGVPeYATPLM
|..| . .... | ... | ... .. .|. . .||...| .
lsrLdaAlgKtpllildgng.....neptaadlellk..........eelydpelf...................erlgikylripvpDgsap.lledfd
TLHKRVMSSSAKGPILVHCSAGWN
. . . . ...||.||||.||..
eflefieeadkggpvlvHCkaGkg
|
|||||||||
0042113 | (Phosphotyrosine protein) phosphatases II | 1490-1593 | 3.3e-23 | 77.8 | In-house | 140-243 (245) | alignment | ||
Range on Protein: 1490-1593
Range on HMM: 140-243/245.0
IVQFQVIGWMNDGVLRDPRTVLQVIDDVIHRQQKIGGGPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQYITIYEAL
..... ..| .|| .....|.... | . ... ..||..||||. |.|||...|. ..||| ..|. |..... | |.. .||||.|..||. .||||
vihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleqlekelgvsleeavkelrsqRpgavqtpsqyrflyeal
EMYL
..|
lell
|
|||||||||
subfamily_Ptp69D_pd | Subfamily Ptp69D | 1489-1595 | 3.6e-23 | 77.1 | In-house | 183-288 (307) | alignment | ||
Range on Protein: 1489-1595
Range on HMM: 183-288/307.0
NIVQFQVIGWMNDGVLRDPRTVLQVIDDVIHRQQKIgGGPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQYITIYEA
..||.. || . | . .|..|..|. | . ... .||||||| |.|.|.. |... |.|.||| ||.|...| |.. .. |. ||||. .| |
kvvqyhytgWkDskvPevargllklieqvrelykln.rsPivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnllvqsleqYvflyra
LEMYLAI
| |
lldyssy
|
|||||||||
subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 1314-1487 | 4.9e-23 | 76.6 | In-house | 46-214 (288) | alignment | ||
Range on Protein: 1314-1487
Range on HMM: 46-214/288.0
LNRFRNIVPYDDNIITLKlpgVAQHEYINASYIHGYSKARKFIAAQGPMKKTLVDFWCLIWQEKPASVVMLTNLVEDSKTKCEQYWPQCLNEIEQFGPFS
.|..|. | . |. . ||.| . |..| || |.. |. .| .. .. .|||..|.| | | ..|.| | | ..| .
rdryenlprcditrvkls...ddpdfyiaanvvssakykrrlicaqaPlngtieelWkmllesdveyivmlcellekGkeksaeyfPsklGekarigrlc
VTLLEDYVMPDYVIRNISVTLQDGSGEVHALTQYHLTTWPDHGVPEYATPLMTLHKRVmsSSAKGPILVHCSAG
.... | ... . . | . . || |.|.|||| . . | ... | . ||.||.|||
tvvkkkradidklvkvsllriskegeekvivkilhlleWdddgvPenylsplrllevl..kslqkPivvhssaG
|
|||||||||
subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 1490-1591 | 2e-21 | 71.2 | In-house | 164-265 (283) | alignment | ||
Range on Protein: 1490-1591
Range on HMM: 164-265/283.0
IVQFQVIGWMNDGVlRDPRTVLQVIDDVIHRQQKIGGGPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQYITIYEAL
. .|||.|.. | . | .. || |.. |||||||| .. ||.|..|.| .... ..| |||||.| | .. ...|| ||.|| ..|.
lahyqvidWleyge.qaiinslvkfnkvislqteskkgPivvhCstgiGrtavfiaasasvkdaltesvvdvfavvkimreqrmmavqtldqyklvhelv
-EM
|
leq
|
|||||||||
0045098 | (Phosphotyrosine protein) phosphatases II | 1489-1594 | 4.7e-21 | 70.8 | In-house | 155-273 (278) | alignment | ||
Range on Protein: 1489-1594
Range on HMM: 155-273/278.0
NIVQFQVIGWMNDGVLRDP--RTVLQVIDDVIHRQQK------------IGGGPIVVHCSDTVSRTGVYCAISIALEQCkaEGVVDVFQVTKALKRSKPG
.. ... ..| || .| . .|.... . ..... .|||..|||| |.|||...|. . ||.. ||.||.... | |.. .||
gvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvlVHCsaGvgRtGtlvaaylmlell..eggvdlleavkelrsqRpg
-AVTTLEQYITIYEALEMYLA
||..||||. .||.| ..|
lavqnleqyrflyefllelll
|
|||||||||
subfamily_PTPN6_pd | Subfamily PTPN6 | 1489-1599 | 5.4e-21 | 69.9 | In-house | 187-303 (306) | alignment | ||
Range on Protein: 1489-1599
Range on HMM: 187-303/306.0
NIVQFQVIGWMNDGVLRDPRTVLQVIDDVIHRQQKIG---GGPIVVHCSDTVSRTGVYCAISIALEQCKAEGV---VDVFQVTKALKRSKPGAVTTLEQY
...|.. | . || .|| .||. ..|| ..|... ||||||||. . ||| . | | |.. . .|. .|. .. | ... . | | | .||
evfqyhfksWPdhgvpkdpgavLdfledvnrkqeeleeaeagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqteqqy
ITIYEALEMYLAINSTY
.|.|...|. ....
kfvykaikkyietkkkl
|
|||||||||
0037934 | (Phosphotyrosine protein) phosphatases II | 1490-1592 | 1.9e-20 | 68.9 | In-house | 135-241 (243) | alignment | ||
Range on Protein: 1490-1592
Range on HMM: 135-241/243.0
IVQFQVIGWMNDGVLRDPRTVLQVIDDVIHRQQK-------IGGGPIVVHCSDTVSRTGVYCAISIALEQCkaeGvVDVFQVTKALKRSKPG-AVTTLEQ
..... ..| || .| .|. .|.|. ... .|||..|||| |.|||...|. . |... | ||.... | |.. .|| ||.|..|
vihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtliaaylmllll...g.vdleeavkllreqRpgkavqtpsq
YITIYEALEMY
|. .|||| ..
yrflyeallel
|
|||||||||
subfamily_CG7180_pd | Subfamily CG7180 | 1491-1597 | 2e-20 | 67.6 | In-house | 183-294 (296) | alignment | ||
Range on Protein: 1491-1597
Range on HMM: 183-294/296.0
VQFQVIGWMN-DGVLRDPRTVLQVIDDVIHRQQKI----GGGPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQYITI
.||. | | | ...... | ..|. ||.||..|| .||.|||.|| ..||. . |. ||||. | |.||.|. | . |.| |
klfqlteWeledkvPlstnalielrrrvrlwrekvdedpeegPvvvvssdGasRsGvylaidanlelvekeeevdvFeavktlrrsRpqLvenveeYkyi
YEALEMYLAINS
|. |. .. |
Ydvlleavlcnk
|
|||||||||
subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 1490-1595 | 2.4e-20 | 67.9 | In-house | 180-291 (325) | alignment | ||
Range on Protein: 1490-1595
Range on HMM: 180-291/325.0
IVQFQVIGWMNDGVLRDPRTVLQVIDDVIHRQQKI-----GGGPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQYIT
. |||. .| . || . | |.. ... | . .... . .||.||||. | ||||. .. ||.. | ||.|.. | |.. .| | | .|||
vkqfqlqswddmGvqkrpatlisilqlvkavservtantkastpilvhcsaGvGrtGvfislysalakvieesrvdifgfvkklrkdrpsmvetvdqyil
IYEALEMYL-AI
||||| .. .
iyealveaymsg
|
|||||||||
subfamily_PTPRG_pd | Subfamily PTPRG | 1490-1594 | 5.4e-20 | 66.1 | In-house | 185-288 (563) | alignment | ||
Range on Protein: 1490-1594
Range on HMM: 185-288/563.0
IVQFQVIGWMNDGVLRDPRTVLQVIDDViHRQQKIGGGPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQYITIYEAL
. |.. | . || . ||. . . .| |||||||| |.|||.|.... |.| ..| .|.||.. | .. .. |.| |||| ...||
vrqyhytkWPdhgvPehslpvLifvkks.saankaeaGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvqteEqYiflhdal
EMYLA
.|
leaia
|
|||||||||
subfamily_egg_pd | Subfamily egg | 1321-1487 | 5.7e-20 | 66.2 | In-house | 50-211 (307) | alignment | ||
Range on Protein: 1321-1487
Range on HMM: 50-211/307.0
VPYDDNIITLKLP-GVAQHEYINASYIHGYSKARKFIAAQGPMKKTLVDFWCLIWQEKPASVVMLTNLVEDskTKCEQYWPQCLNEIEQF--GPFSVTLL
| ..|.|. | ..| | ...| .|| || |.| | ||| ...||. .|||| .| .|| |||.. .. .. | . .. |
hckdssrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvddfwrmvfqeevqyivmltsrkes..erceyywpkaesdslvtvpGslrienl
EDYVMPDYVIRNISVTLQDGSGEVHALTQYHlttWPDHGVPEYATPLMTLHKRVmssSAKGPILVHCSAG
. . .| . | . | | | | . . . . . .|| | | . |..|.. |
kvdskadplfrvtklklvGgddeerflehwq...gdvnnssdvysplrvlrklr...nlskpvvvqdilG
|
|||||||||
subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 1489-1593 | 1.5e-19 | 65.1 | In-house | 176-280 (315) | alignment | ||
Range on Protein: 1489-1593
Range on HMM: 176-280/315.0
NIVQFQVIGWMNDGVLRDPRTVLQVIDDVIHRQQKIGgGPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQYITIYEA
..||... | . || . .....| | ... |.||||||. | ||| ..... |.| .|| ..||... . ... . ..| ..||| ||.|
evvqlhytswpdmgvpkytiplmnlirtvkqhhtnsv.gaivvhcsaGvGrtGtfitldavldqaeaenaidvynfitgvrqnrikmvqvaeqyqfiyda
L-EMYL
| | ..
lletfv
|
|||||||||
0044763 | (Phosphotyrosine protein) phosphatases II | 1331-1489 | 2.7e-19 | 65.0 | In-house | 11-122 (178) | alignment | ||
Range on Protein: 1331-1489
Range on HMM: 11-122/178.0
KLPGVAQHEYINASYIHGYskarKFIAAQGPmkktlVDFWCLIWQEKPASVVMLTNLVEDSKTKCEQYWPQCLNeieqfgpfsvtlledyvmpdyvirni
.|.|. .|||||.| .. ......| .|.. |..... ..|.||. .| . || .|||. .
nleglersdyinaseilpg....lylgslpp.....addlellkelgithivnlteelelgflkcdpywpeeag..........................
svtlqdgsgevhalTQYHLTTWPDHGVPEYATPLMTLHKRVMSS--SAKGPILVHCSAGWN
||. . .||||||. .. ... . . . .||.|||||||..
..............iqylhipipDhgvpdllehflefvefieealdekggpvlVHCsaGvg
|
|||||||||
subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 1489-1589 | 4.1e-19 | 64.0 | In-house | 186-287 (319) | alignment | ||
Range on Protein: 1489-1589
Range on HMM: 186-287/319.0
NIVQFQVIGWMNDGVLRDPRTVLQVIDDVIHRQQKIGG-GPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQYITIYE
.| || || . || | ...... | | ..| . .|||||| | ||||| .. . |.. | | |||... . |.. .. | | || ||
kitqfhflGwpdvGvpdypsdlmrlvkkvrhltskenhranivvhcsaGvGrtGvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiys
AL
||
al
|
|||||||||
subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 1489-1590 | 4.3e-19 | 63.6 | In-house | 176-276 (288) | alignment | ||
Range on Protein: 1489-1590
Range on HMM: 176-276/288.0
NIVQFQVIGWMNDGVLRDPRTVLQVIDDVIHRQQKIgGGPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQYITIYEA
.| |.| .| ..|| .. . .|.... | .|. |||.||||. | |||.. |. .... ..| ..||. . . |..... | ||.||. |||.
eitqyqylaWpdhgvPeskapllellrqvkvanqad.tgpiivhCsaGvGrtgtFialdalidaveeedyiDvagtvaklRkqRallvqtlkqYefiyev
LE
|
ll
|
|||||||||
subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 1491-1598 | 5.4e-19 | 63.4 | In-house | 180-289 (297) | alignment | ||
Range on Protein: 1491-1598
Range on HMM: 180-289/297.0
VQFQVIGWMNDGVLR--DPRTVLQVIDDVIHRQQKIGGGPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQYITIYEA
|.| . | .. | | . ...|..|..| . .. ||..|||. | ||||...| . . | | ||.|.. | |....| | | ||| .|.|
kqyqfveWPdkaverkdsassllklisevrkdfsqnaegPllvhclaGvGrtgvlltidsvvaeakrekevdifglvkklrqerpylvqtkeqykfvyva
LEMYLAINST
. .| . |
vleallsedt
|
|||||||||
subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 1490-1597 | 6e-19 | 63.0 | In-house | 175-281 (315) | alignment | ||
Range on Protein: 1490-1597
Range on HMM: 175-281/315.0
IVQFQVIGWMNDGVLRDPRTVLQVIDDVIHRqQKIGGGPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQYITIYEAL
. ||| .| . || .. ..|..| .| .. ...|||| | |||| ..| ..| | . .||||.. | |.. .| | | |.| ||.|.
vtqfqftewPdkGvdkqtssllklikevkad.ngkkefsllvhcsaGvGrtGvvisidevvaqikrtrsvdvfnfvknlrakrpylvqteeeyafiydav
EMYLAINS
.|
ledllwrn
|
|||||||||
subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 1497-1593 | 6.4e-19 | 63.1 | In-house | 170-268 (274) | alignment | ||
Range on Protein: 1497-1593
Range on HMM: 170-268/274.0
GWMNDGVLRDPRTVLQVIDDVIHRQQKI--GGGPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQYITIYEALEMYL
| . . .|..|.|.....| . ... .|.||||| . |||.. |||||. | ..|.||||.... |. . | | | ||| |..|| .||
dWPdhksPddantlldlvleveesreeenaklapvvvhCsaGiGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralclyl
|
|||||||||
subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 1490-1596 | 6.7e-19 | 62.4 | In-house | 174-279 (515) | alignment | ||
Range on Protein: 1490-1596
Range on HMM: 174-279/515.0
IVQFQVIGWMNDGVLRDPRTVLQVIDDVIHRQQKIGgGPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQYITIYEAL
. ||. .| . || .. ...|..| .| .... |...||| | ||||...| . . | .||||.. . ... .| | | ||| ||.|.
vtqfhfteWPdkGvpkhtssllklikevkadhgqyt.hpliihcsaGvGrtGvvisidsvvahakttrmvdvfnfvtnirqkrpylvqtqeqyafiygav
EMYLAIN
.|
ledllwr
|
|||||||||
subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 1489-1589 | 6.8e-19 | 63.4 | In-house | 150-251 (284) | alignment | ||
Range on Protein: 1489-1589
Range on HMM: 150-251/284.0
NIVQFQVIGWMNDGVLRDPRTVLQVIDDVIHRQQKIGG-GPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQYITIYE
.| || || . || | ...... | | ..| . .|||||| | ||||| .. . |.. | | |||... . |.. .. | | || ||
kirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrtgvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiys
AL
||
al
|
|||||||||
0051082 | (Phosphotyrosine protein) phosphatases II | 1339-1489 | 1.3e-18 | 62.5 | In-house | 4-104 (151) | alignment | ||
Range on Protein: 1339-1489
Range on HMM: 4-104/151.0
EYINASYIHGYskarkFIAAQGPMKktlvDFWCLIWQEKPASVVMLTNLVEDSktKCEQYWPQCLneieqfgpfsvtlledyvmpdyvirnisvtlqdgs
|||.||. |. ... .||. ||. |..... ..|.|....| .| .|.|.
dyinfsyvtgg.....lyrsggpla....dflellkelgiktivnlrseeerg..ycpeylpelg...................................
gevHALTQYHLTTWPDHGVPEYATPLMTLHKRVMSsSAKGPILVHCSAGWN
. ....... |||.|.|.. .. ... ... .||.|||||||..
...ievlhipildwpdpglplsfdavleflellld.kkngpvlvHCsaGkg
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 1297-1401 | 1.7e-18 | 61.5 | In-house | 35-152 (350) | alignment | ||
Range on Protein: 1297-1401
Range on HMM: 35-152/350.0
SGNDKQCSVGLNGMNKplNRFRNIVPYDDNIITLK----L-----PGVAQHEYINASYIHGY----SKARKF--IAAQGPMKKTLVDFWCLIWQEKPASV
|| . | |.. . | ||..||.||. . . || . .||||.|.. . .| ||.|.|...|. ||. .| . | .
psnDvilseGvelfak..nrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvi
VMLTNLVEDSKTKCEQYWPQ
..||..|| ||..||..
lsltsdvelnlekcyrYWqe
|
|||||||||
subfamily_PTPRB_pd | Subfamily PTPRB | 1490-1593 | 2.7e-18 | 61.1 | In-house | 181-285 (293) | alignment | ||
Range on Protein: 1490-1593
Range on HMM: 181-285/293.0
IVQFQVIGWMNDGVLRDPRTVLQVIDDVIHRQ-QKIGGGPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQYITIYEA
. |.. . | . || ...|.|. . | ... .. .||||||| | |||.. |. |.. . | .||.| . .|.... | | .||| |...
vrqyhftsWpdhgvPektktlldfvrtvreaiektaskrPivvhCsaGvGRtGtfialdrllqaieeedyvdifgivaelReeRnllvqtekqYifihqc
LEMYL
. .|
vldll
|
|||||||||
subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 1301-1489 | 3.8e-18 | 60.2 | In-house | 35-221 (312) | alignment | ||
Range on Protein: 1301-1489
Range on HMM: 35-221/312.0
KQCSVGLNgmNKPLNRFRNIVPYDDNIITLKlpGvAQHEYINASYIHGYSKARKFIAAQGPMKKTLVDFWCLIWQEKPASVVMLTNLVEDSKTKCEQYWP
.|. |. | |||. || .| .|| | . || | ... .| .|...|||...| . || | .|...|. .|||. || .|
sectaflk..fkdlnrypniqcwdrgrftla..g.denfyihanfvkictkperfvctqgplentcthfwqlalslgstsiillcgfvedgsekcakyis
QCL--NEIEQFGPFSVTLLEDY---VMPDYVIRNISVTLQDGSGEVHALTQYHLTTWPDHGVPEYATPLMTLHKRVMssSAKGPILVHCSAGWN
. . ..|. .. | | . . . .|. | .| ..|||||.|. . | | | |.. |||||
divgfvdledhrvyteycteieiggkskdkithrvlkvvvkatgqesklnhyqwaswpdhgmpdscdtalrllsavk..kdkkpviahcsagvg
|
|||||||||
subfamily_PTPN12_pd | Subfamily PTPN12 | 1489-1592 | 1.4e-17 | 58.5 | In-house | 171-276 (290) | alignment | ||
Range on Protein: 1489-1592
Range on HMM: 171-276/290.0
NIVQFQVIGWMNDGVLRDPRTVLQVIDDVIHRQQkIGGGPIVVHCSDTVSRTGVYCAISIALEQCKAEGV---VDVFQVTKALKRSKPGAVTTLEQYITI
.. ||. | . || . . ..|..|..| ..|. |.||||| | |||. .|| .. |. ||| . .|||.. |.. .. .| | ||| .
kvyqfhYtaWPDhgvPssaksllelielvrelqe.sedaPlvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelv
YEALEMY
|.|.. .
ykavael
|
|||||||||
0036282 | (Phosphotyrosine protein) phosphatases II | 1490-1587 | 2.1e-17 | 58.8 | In-house | 69-164 (174) | alignment | ||
Range on Protein: 1490-1587
Range on HMM: 69-164/174.0
IVQFQVIGWMNDGVLRDPRtVLQVIDDVIHRQQKIGGGPIVVHCSDTVSRTGVYCAISIALEQCKaEGVVDVFQVTKALKRSKPGAVTTLEQYITIYE
..|.. ..| .|| .. .|.... | . ... .|||..|||| |.|||. .|. . | . . |..||.... ..|.. .||.|.| .||. .|.
giqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtpsQyrflyy
|
|||||||||
0051429 | (Phosphotyrosine protein) phosphatases II | 1490-1594 | 2e-16 | 56.0 | In-house | 122-226 (272) | alignment | ||
Range on Protein: 1490-1594
Range on HMM: 122-226/272.0
IVQFQVIGWMNDGVLRDPrtVLQVIDDVIHrqqkigGGPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVD--------VFQVTKALKRSKPGAVTTLEQ
. ... ..| .|| ... .|.... . . |||..|||| ..|||...|. . |.. .| .|| .... . |.. |||| | ||
vmhlhytdwpdhgvpqea..llellellld......ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlyleeaveelraqrpgavqteeq
YITIYEALEMYLA
|. .|||| .|
ylflyeallellr
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 1490-1591 | 2.8e-16 | 53.9 | In-house | 91-192 (440) | alignment | ||
Range on Protein: 1490-1591
Range on HMM: 91-192/440.0
IVQFQVIGWMNDGVLRDPRTVLQVIDDVIHRQQKIGGGPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQYITIYEAL
. |.. || . || . ||..|.|| . |.| | ||..|||| ..|||| |. | ..| .|.| . .... ..| | | ||| ..||.
lkqyhyqgwpdkgvpkfagpvlkmiqdvnesqekagngpllvhcsagagrtgviiavdsilreakrsdqidifsfinsmrnnrpqmvqtpeqyafvheav
EM
le
|
|||||||||
subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 1338-1487 | 3.9e-16 | 54.0 | In-house | 46-201 (290) | alignment | ||
Range on Protein: 1338-1487
Range on HMM: 46-201/290.0
HEYINASYIHgYSKARKFIAAQGPMKKT-------LVDFWCLIWQEKPASVVMLTNLVEDSKT----KCEQYWPQCLNEIEQFGPFSVTLLEDYVMPDYV
.|| |... ... ..|. | | .|. . .|| .. ||| .|||| . | |. |..| |. .|. .|. ..| . |
ddyiHAnrvt.cpnglrliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCakYvpesvgeelkfkgltvkCkskekeddve
IRNISVTLQDGsgEVHALTQYHLTTWPDHGVPEYATPLMTLHKRVMssSAKGPILVHCSAG
.|.. |. .|. | . .| . | | . |.| |..| . |. | |..||| |
tRelvvkfdde..eeftvtHsllkgWnklnvqedtktllsliqkvk..asktpvivHcvdG
|
|||||||||
subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 1365-1487 | 4.1e-16 | 53.8 | In-house | 40-158 (255) | alignment | ||
Range on Protein: 1365-1487
Range on HMM: 40-158/255.0
TLVDFWCLIWQEKPASVVMLTNLVEDSKTKCEQYWPQCLNEIEQFGPFSVTLLEdyVMPDYVIRNISVTLQDG-SGEVHALTQYHLTTWPDHGVPEYATP
|. |. | | |. ||||... |... ||..|.| ..| .. .|| . . | |.| . .|.. | . | .. |. . |... || |
tvdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdeklkladvnvtttk..ssadvvlrtleitstlgekkkthtvkhysykGWieknaPelare
LMTLHKRVMSSsakGPILVHCSAG
.. . | | | ...||||.|
ilnilkvvrds...ksvvvhCstG
|
|||||||||
subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 1490-1594 | 4.9e-16 | 53.5 | In-house | 154-265 (270) | alignment | ||
Range on Protein: 1490-1594
Range on HMM: 154-265/270.0
IVQFQVIGWMNDGVLRDPR------TVLQVIDDV-IHRQQKIGGGPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQY
.| |. | ..|| |.. .|... .| ..... ..|..||||. | |||. |. ||.. . .. ||| .. ..|.. .. | . |||
lvHfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcsaGvgRtGtlialDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqy
ITIYEALEMYLA
.|.|. .|
eflykavveyae
|
|||||||||
subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 1490-1589 | 7.7e-16 | 52.6 | In-house | 176-275 (439) | alignment | ||
Range on Protein: 1490-1589
Range on HMM: 176-275/439.0
IVQFQVIGWMNDGVLRDPRTVLQVIDDVIHRQQKIGGGPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQYITIYEAL
..||. | | . | . ||. . . ..| ||.||||| | ||| |. ||||| |.| ||. . | |.. . | .| ||. ||.|.
vlqfhyiawpdknvpaqashvldflrainsandkeeygpvvvhcsagvGrtGtiialdialeqlklenkvdikgivkvlrkqrkqmvqalcqyvfiynav
|
|||||||||
subfamily_PTPN13_pd | Subfamily PTPN13 | 1489-1590 | 1.2e-15 | 52.5 | In-house | 167-266 (273) | alignment | ||
Range on Protein: 1489-1590
Range on HMM: 167-266/273.0
NIVQFQVIGWMNDGVLRDPRTVLQVIDDVIHRQQkiGGGPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQYITIYEA
...... . | . || . . .||.. | . |. |||||||| . |.|.. .| ..|. . . .|| .. . |.. . | | | .||| .|.|
evahlnfvkwPdhgvPssaaellqfvaevrrlqt..dagPivvhcsaGiGrsGtlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvyka
LE
.
il
|
|||||||||
0041856 | (Phosphotyrosine protein) phosphatases II | 1490-1595 | 1.3e-15 | 53.0 | In-house | 79-173 (182) | alignment | ||
Range on Protein: 1490-1595
Range on HMM: 79-173/182.0
IVQFQVIGWMNDGVLRdPRTVLQVIDDVIHrqqkiGGGPIVVHCSDTVSRTGVYCAISIALEQckaeGvVDVFQVTKALKRSKPGAVTTLEQYITIYEAL
..|.. ..| .|| ....|. |..|.. |||..|||| |.|||...|. . ... | |..... | ... .||.|.|..||. .. ||
giqylylpwpDhgvpd.ldelldfieevle.....eggpvlVHCsaGvgRtgtlvaaylmkkl....g.vsleeavklvrsrRpgmvitpnqyfflqlal
EMYLAI
..|
lellll
|
|||||||||
subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 1519-1592 | 1.6e-15 | 51.9 | In-house | 185-258 (267) | alignment | ||
Range on Protein: 1519-1592
Range on HMM: 185-258/267.0
HRQQKIGGGPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQYITIYEALEMY
. | . |. |.||.||| | |.| . | ||. | |||.|.|. . .. ..| | |.|.|| |.| | |
knqlengnrPlvvacsdGvGrsGtflvidsqleraktegvsdifdflrkirsqriglvdtkeryiyihellaey
|
|||||||||
0043147 | (Phosphotyrosine protein) phosphatases II | 1490-1588 | 1.9e-15 | 52.4 | In-house | 65-156 (172) | alignment | ||
Range on Protein: 1490-1588
Range on HMM: 65-156/172.0
IVQFQVIGWMNDGVLrDPRTVLQVIDDVIHRQQKIGGGPIVVHCSDTVSRTGVYCAISIALeqckaeG-VvDVFQVTKALKRSKPGAVTTLEQYITIYEA
..|.. ..| || ... .|.... . ..... |||..|||| |.|||. .|. . | . ..... . ... .||||.. .||. .|.
giqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml......lgl.sleeavalvrekRpgavqnpsqyrflyyf
|
|||||||||
subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 1489-1593 | 8.8e-15 | 49.6 | In-house | 171-276 (281) | alignment | ||
Range on Protein: 1489-1593
Range on HMM: 171-276/281.0
NIVQFQVIGWMNDGVLRDPRTVLQVIDDVIHRQQKIGGGPIVVHCSDTVSRTGVYCAISIALEQCKAE-GVVDVFQVTKALKRSKPGAVTTLEQYITIYE
...|.. . | . || ... .|. ..| . ..| |.|.||| | |||.| |. ......|| .|| .| . |.... | |. || .|
eveqlaytaWPdhGvPattkellefrkevlkltekktkaplvihCsaGvGrtGtyialDrlvkaveaeleeldvkavvaelrkernlmvqtvvqyefvyk
ALEMYL
|. .|
avldal
|
|||||||||
subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 1490-1588 | 1.9e-14 | 48.5 | In-house | 135-234 (237) | alignment | ||
Range on Protein: 1490-1588
Range on HMM: 135-234/237.0
IVQFQVIGWMNDGVLRDPRTVLQVIDDVIHRQQKI-GGGPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQYITIYEA
| |.| | . || . ..|. ..|.| ... || ..||| | |||.. | | |.| . |||... .... .| . | .||. |...
ihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlrqakekkvvdiynyvysieedrpyiiqtkdqyvfihqt
|
|||||||||
subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 1352-1490 | 5.7e-14 | 46.7 | In-house | 4-148 (199) | alignment | ||
Range on Protein: 1352-1490
Range on HMM: 4-148/199.0
ARKFIAAQGPMKKTLVDFWCLIWQEKPASVVMLTNLVEDSKTKCEQYWPQCLNEIEQFGPFSVTLLEDYVMPDYVIRNISVTLQDG-SGEVHALTQYHLT
|..||.| |...|. ||| ..|. .||. . . .. ||| . . ..| .||| . |||.| . .| . ...| .|
qrryiatqhplretmadfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqft
TWPDHGVPEYATPLM-TLHKRVMSS----SAKGPILVHCSAGWNI
.| .. |. | . . | .| |..|||| | .
swkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgf
|
|||||||||
subfamily_eak_pd | Subfamily eak | 1317-1469 | 5.9e-14 | 46.2 | In-house | 57-205 (332) | alignment | ||
Range on Protein: 1317-1469
Range on HMM: 57-205/332.0
FRNIVPYDDNIITLKLPGVAQHEYINASYIHGYSKARKFIAAQGPMKKTLVDFWCLIWQEKPASVVMLTNLVEDSKTKCEQYWPQCLNEIEQFGPFSVTL
.||||| . . | . ||||| . ||.| . . .. . || .. ..| ..|.| . || | ..|.|. | .|| . |.
vvkivpydrylvrltssqlnrlGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledvelkleksdkyfpdktreelkfGildver
lEDYVMPD-YVIRNIsvTLQDGSgEVHALTQYHLTTWPDHGVPEYATpLMTLHK
..| . . |.. |. | | | . |.. | . .| | ...|.|
.kefvkrniletrll..elskGn.ethrvlhykvfGwtettlpkyed.flalrk
|
|||||||||
subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 1352-1490 | 6.8e-14 | 46.5 | In-house | 3-147 (198) | alignment | ||
Range on Protein: 1352-1490
Range on HMM: 3-147/198.0
ARKFIAAQGPMKKTLVDFWCLIWQEKPASVVMLTNLVEDSKTKCEQYWPQCLNEIEQFGPFSVTLLEDYVMPDYVIRNISVTLQDG-SGEVHALTQYHLT
|..||.| |...|| ||| ..|. .||. . . .. ||| . . ..| .||| . |||.| . .| . ...| .|
qrryiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqft
TWPDHGVPEYATPLM-TLHKRVMSS----SAKGPILVHCSAGWNI
.| .. |. | . . | .| |..|||| | .
swkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgf
|
|||||||||
0048076 | (Phosphotyrosine protein) phosphatases II | 1490-1592 | 1.1e-13 | 46.6 | In-house | 47-142 (145) | alignment | ||
Range on Protein: 1490-1592
Range on HMM: 47-142/145.0
IVQFQVIGWMNDGVLRDPRTVLQVIDDVIHRQQKigGGPIVVHCSDTVSRTGVYCAISIALEqckaEGvVDVFQVTKALKRSKPGAVTTLEQYITIYEAL
..|.. ..| || .....|.... . . ... |||..|||| |.|||...|. . |. .| |..... . ... ||||.. .|.. .||..
giqylylpwpDhgvpdllellleflefieealke..ggpvlVHCsaGvgRtgtlvaaylmll....lg.vsleealelvrsqrpgavpnpgqlrflyefe
EMY
...
lel
|
|||||||||
subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 1490-1588 | 1.5e-13 | 45.5 | In-house | 138-235 (239) | alignment | ||
Range on Protein: 1490-1588
Range on HMM: 138-235/239.0
IVQFQVIGWMNDGVLRDPRTVLQVIdDVIHRQQKIGGGPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQYITIYEA
. |... | . || . .|| . | .. | | |.||| | ||| . | | |.| . ||.|. ||.. .| | | |||. |. |
vyqyhftvwpdkgvpqyatavlglr.rkitkdslpgarpwvihcsagvgrtgaflvidamlrqakkqktvdifnyvkairedrphmvqtseqyvfihla
|
|||||||||
subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 1490-1588 | 1.7e-13 | 45.3 | In-house | 139-236 (239) | alignment | ||
Range on Protein: 1490-1588
Range on HMM: 139-236/239.0
IVQFQVIGWMNDGVLRDPRTVLQVIdDVIHRQQKIGGGPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQYITIYEA
. |... | . || . .|| . | .. | | |.||| | ||| . | | |.| . ||.|. ||.. .| | | |||. |. |
vyqyhftvwpdkgvpqyatavlglr.rkitkdslpgarpwvihcsagvgrtgaflvidamlrqakkqktvdifnyvkairedrphmvqtseqyvfihla
|
|||||||||
subfamily_Sponge-PTP3_pd | Subfamily Sponge-PTP3 | 1267-1360 | 1.9e-13 | 44.4 | In-house | 4-95 (95) | alignment | ||
Range on Protein: 1267-1360
Range on HMM: 4-95/95.0
PISLNDLGNHVACCHSDSNAYFSEQFKDLYSGNDKQCSVGLNGMNKPLNRFRNIVPYDDNIITLKlpGVAQHEYINASYIHGYSKARKFIAAQG
|| . . || ||.|. | ..|| . .|| | | ||| ||.||| ..| . .|||| .. ||.. .|||||
pihvsvfhshvlemhsnsdqefdnefksismtsgapytvgsseanipknrflnifpydatrvvlt..tkrdsdyinacfvdgyarkncyiaaqg
|
|||||||||
0046846 | (Phosphotyrosine protein) phosphatases II | 1492-1592 | 2.1e-13 | 45.9 | In-house | 78-172 (176) | alignment | ||
Range on Protein: 1492-1592
Range on HMM: 78-172/176.0
QFQVIGWMNDGVLRDpRTVLQVIDDVIHRQQKigGGPIVVHCSDTVSRTGVYCAISialeQCKAEGVVDVFQVTKALKRSKP-GAVTTLEQYITIYEALE
|.....| || . . .|.... . .... |||..|||| ..|||...|. .. | ..|... . ... .| |||.| ||| .||..
qylhlpwpDhgvpdl.elllellefirealke..ggpvlVHCsaGigRtgtlvaay....llelekglsveealalvreqRplgavqtpeQyrflyefel
MY
..
ll
|
|||||||||
subfamily_PTPN9_pd | Subfamily PTPN9 | 1489-1592 | 3.1e-13 | 44.4 | In-house | 174-289 (297) | alignment | ||
Range on Protein: 1489-1592
Range on HMM: 174-289/297.0
NIVQFQVIGWMNDGVLRDPRTVLQVIDDVIHRQQ------------KIGGGPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAV
... ||...| . || .. ..|.|.. | ..| .. | ||||||| . ||| .... |.|.. . .|.|||... | |. . ..
kvthfqflsWPdyGvPssaaslldvlekvrekqalavkelgdewkghpsgPPivvhcsaGiGrtGtfitldiclsrleevgtvdvvetvkllrtqrafsi
TTLEQYITIYEALEMY
| ||| | |. |
qtpeqyefcylavley
|
|||||||||
subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 1490-1590 | 4.2e-13 | 43.4 | In-house | 134-233 (392) | alignment | ||
Range on Protein: 1490-1590
Range on HMM: 134-233/392.0
IVQFQVIGWMNDGVLRDPRTVLQVIDDVIHRQQKIgGGPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQYITIYEAL
. ||.. | ...| . ..|..| .| . |...||| | |||| .| . ..| .||||.. ..| .| | | ||| || |.
vaqfhftewPdkdvpkhtssllkfikevkadfGqy.thpliihcsagvgrtgvvisidsvvahakktrmvdvfnfvtnirrkrpymvqtkeqyafiygav
E
l
|
|||||||||
subfamily_PTPN3_pd | Subfamily PTPN3 | 1489-1588 | 4.6e-13 | 43.7 | In-house | 172-270 (280) | alignment | ||
Range on Protein: 1489-1588
Range on HMM: 172-270/280.0
NIVQFQVIGWMNDGVLRDPRTVLQVIDDViHRQQKIGGGPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQYITIYEA
.|.|.| . | . || |. .|.... | ..... |.||||| . ||||. .. .|| |. | . .. . .. . | | .|| . ||
kilqlqylaWpdhgvPddsadflefverv.rklrsgkeePvvvhCsaGigrtGvlilletalalieaaepvypldivrtmrdqramlvqtasqykfvCea
|
|||||||||
0049260 | (Phosphotyrosine protein) phosphatases II | 1492-1587 | 5e-13 | 44.5 | In-house | 56-144 (152) | alignment | ||
Range on Protein: 1492-1587
Range on HMM: 56-144/152.0
QFQVIGWMNDGVLRDPRTVLQvIDDVIHRQQKIGGGPIVVHCSDTVSRTGVYCAISIALeqckaeGVVDVFQVTKALKRSKPGAVTTLEQYITIYE
|.. . | .|| .. .|. . ..|.. .. |||..|||| |.|||...|. . | |..... . ... .||||.. .|.. .||
qylhlpwpDhgvpdlsqlllf.lllfieklaldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpgqlrflye
|
|||||||||
0051082 | (Phosphotyrosine protein) phosphatases II | 1488-1589 | 6.8e-13 | 44.0 | In-house | 58-149 (151) | alignment | ||
Range on Protein: 1488-1589
Range on HMM: 58-149/151.0
WNIVQFQVIGWMNDGVLRDPRTVLQVIDDVIHrqqkIGGGPIVVHCSDTVSRTGVYCAISIALEQckaegvVDVFQVTKALKRSKPGAVTTLEQYITIYE
.........| . |. . .||.... ... ..||..|||| ..|||. .|. . |.. |..... . .... ||.|.. .|.. ..
ievlhipildwpdpglplsfdavleflellld....kkngpvlvHCsaGkgRTGtlvalylmllg......vsleealeeyrlkrpgvvqpnqqflfqlf
AL
||
al
|
|||||||||
fn3 | Fibronectin type III domain | 594-669 | 9.8e-13 | 41.2 | Pfam-A | 1-79 (85) | alignment | ||
Range on Protein: 594-669
Range on HMM: 1-79/85.0
SAPSSLTEVNKTATTITVNWNALD--SSDADGYVVNVTSDTDT--VQTVQVEGSSNnTITLNGLRAVTNYSITVRAYQQL
|||. |. . |.|..|..|.. . ... .|| | . ..... ....|..... . ||.||.. |.|...|.|. .
saPenlsvsevtstsltlsWsppkdgggpitgYeveyrekgggeewkeftvprttt.svtltgLkpgteYefrVqavnga
|
|||||||||
subfamily_PTPN23_pd | Subfamily PTPN23 | 1490-1589 | 1.7e-12 | 41.7 | In-house | 173-276 (288) | alignment | ||
Range on Protein: 1490-1589
Range on HMM: 173-276/288.0
IVQFQVIGWMNDGVLRDPRTVLQVIDDVIH---RQQKIGGGPIVVHCSDTVSRTGVYCAISIALEQC-KAEGVVDVFQVTKALKRSKPGAVTTLEQYITI
.. |. | . || | |.||..| | . .|. |.||||| | ||||.. . |... | .|..|. || . |.. . | . ||.
vshlqltsWpelGvPasPetllqfldevesayeavqrksktPlvvhCsaGvgRtgvfalvyaavrelekgnglldiiqvvsrlreqRrfmvqekeqlkfs
YEAL
|||
yeav
|
|||||||||
0048179 | (Phosphotyrosine protein) phosphatases II | 1490-1587 | 1.8e-12 | 42.7 | In-house | 49-139 (144) | alignment | ||
Range on Protein: 1490-1587
Range on HMM: 49-139/144.0
IVQFQVIGWMNDGVLRDPRTVLQVIDDVIHRQQkiGGGPIVVHCSDTVSRTGVYCAISIALeqckAEGvVDVFQVTKALKRSKPGAVTTLEQYITIYE
..|.. ..| . || .. .|.... . . .. |||..|||| |.|||...|. . . .| ...... . ... ||||.. .|.. ..|
giqylhlpwpDhgvpdllellleflefieeale..eggpvlVHCsaGvgRtgtlvaaylmk....klg.lsleealalvrsrrpgavpnpgqlrfLle
|
|||||||||
subfamily_hpo-7_pd | Subfamily hpo-7 | 1364-1487 | 2.7e-12 | 41.2 | In-house | 45-164 (263) | alignment | ||
Range on Protein: 1364-1487
Range on HMM: 45-164/263.0
KTLVDFWCLIWQEKPASVVMLTNLVEDSKTKCEQYWPQCLNEIEQFGPFSVTLLEDYVmpDYVIRNISVTLQDG-SGEVHALTQYHLTTWPDHGVPEYAT
.|. |. | | |. ||||.. |... ||..|.| ..| .. .|. . | ... . .. . | ..| ...| . |... || |
qtidkfyqtivqtktevvvmLcDfneegvekcssyfPlekdekqklanvnvcttkvqs..dvllktlellstlgeKkkthtvkhysykgWiekndpelar
PLMTLHKRVMSSsakGPILVHCSAG
. . | . | .. ||||.|
eilnilkvarns...kslvvhcstG
|
|||||||||
subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 1358-1487 | 4.3e-12 | 40.1 | In-house | 96-231 (302) | alignment | ||
Range on Protein: 1358-1487
Range on HMM: 96-231/302.0
AQGPMKKTLVDFWCLIWQEKPASVVMLTNLVEDSKTKCEQYWPQCLNEIEQFGPFSVTL------LEDYV-MPDYVIRNISVTLQDGSGEVH-ALTQYHL
| |.|| .|.|| | . | || |...||| . || .|. . ... .|| ..|. ||.. .... .. .. . .|. .. .
pivpkkstlekhwalieqynvaivvqlcsfvedeekkcaeyysdkvggelkfgrytvktvsvktdleeftdkksfklytveiknekkkkkvkktvdilaf
TTWPDHGVPEYATPLMTLHKrvMSSSAKGPILVHCSAG
..||||| |. | . . . | | | .|||||||
sawpdhGapkeaytaldilk..fcesykknvlvhcsaG
|
|||||||||
0049772 | (Phosphotyrosine protein) phosphatases II | 1491-1594 | 8.5e-12 | 40.9 | In-house | 181-281 (314) | alignment | ||
Range on Protein: 1491-1594
Range on HMM: 181-281/314.0
VQFQVIGWMNdGVLRDPRTVLQVIdDVIHRQqkIGGGPIVVHCSDTVSRTGVYCAISIALEQCkaeGVvDVFQVTKALKRSKP-----GAVTTLEQYITI
... | . | ... ..... ..|.. |||..|||.. ..|||..... . . .. || .. .. . ... | |.. .||||. |
ikylripvpD.gsaplledfdefl.efieea..dkggpvlvHCkaGkgRtgtfvvaaylmkll...gv.sleealedvrlkRpinpnpgfieqleqyefi
YEALEMYLA
.|||..||
lealleylk
|
|||||||||
PTPc_DSPc_SM00012 | 1445-1489 | 4.6e-11 | 38.2 | In-house | 3-51 (105) | alignment | |||
Range on Protein: 1445-1489
Range on HMM: 3-51/105.0
TQYHLTTWPDHGVPEYATPLMTLHKRVMSSSAK----GPILVHCSAGWN
..|| |.||||||||.......| . |... | .|..||||||..
khyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvg
|
|||||||||
subfamily_PTPN14_pd | Subfamily PTPN14 | 1490-1593 | 6.7e-11 | 36.7 | In-house | 185-296 (300) | alignment | ||
Range on Protein: 1490-1593
Range on HMM: 185-296/300.0
IVQFQVIGWMNDGVLRDPRTVLQVIDDV---I-HRQQKI----GGGPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQ
.. .| . | ..|| .|... |. ...| . .... |..||||. | |||| . .. . . ..|. .| . |.. . | || |
vwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseveskeskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLreqrmllvqtlaq
YITIYEALEMYL
| .|..| ||
YkfvYkvlikyl
|
|||||||||
subfamily_PTPRN_pd | Subfamily PTPRN | 1490-1588 | 6.7e-11 | 36.4 | In-house | 189-287 (297) | alignment | ||
Range on Protein: 1490-1588
Range on HMM: 189-287/297.0
IVQFQVIGWMNDGVLRDPRTVLQVIDDVIhRQQKIGGGPIVVHCSDTVSRTGVYCAISIALEQC-KAEGVVDVFQVTKALKRSKPGAVTTLEQYITIYEA
. || . | . || ....|. | . . |||||||| . |||||..| . |.. | .|. . |. .|| | | .|. .. |
vtqfhflswpeegvPasaksllefrrkvn.ksyrGrscpivvhcsdGaGrtGvyilidlvlnrllkGvkeidiaatlehlrdqrpglvktkdqfefalta
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 1347-1415 | 9.9e-11 | 35.6 | In-house | 230-294 (440) | alignment | ||
Range on Protein: 1347-1415
Range on HMM: 230-294/440.0
HGYSKARKFIAAQGPMKKTLVDFWCLIWQEKPASVVMLTNLVEdsKTkCEQYWPQCLNEIeQFGPFSVT
.|||| |||.| |. |..||| |. . . ....|| .| . || | ||| . ||||.|
egyskknafiatqmpldstvldfwrlvhdyristiimlnqlnd..kt.csiywpvntrsv.tfgpftvg
|
|||||||||
subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 1490-1597 | 1.1e-10 | 35.8 | In-house | 170-281 (287) | alignment | ||
Range on Protein: 1490-1597
Range on HMM: 170-281/287.0
IVQFQVIGWmNDGVLRDP-----RTVLQVIDDVIHRQQKIGGGPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQYIT
. |.... | |.|| | ||.| . . ... . ||.|||.. . |.|.. |. . ... . | ||| .| |. . . | . |.
vkqldllsw.PdkvlaPtavglirfvldvkqhielardasevGPlvvhddvGiGrsGillatlvlvsrledlGrvdvaavvirlreyraalvqavvqlrl
IYEALEMYLAINS
.|||| | |
lyealvtyyktnp
|
|||||||||
0044763 | (Phosphotyrosine protein) phosphatases II | 1492-1596 | 1.1e-10 | 36.9 | In-house | 77-174 (178) | alignment | ||
Range on Protein: 1492-1596
Range on HMM: 77-174/178.0
QFQVIGWMNDGVLRDPRTVLQVIdDVIHRQQKIGGGPIVVHCSDTVSRTGVYCAISIALEQckaeGVvDVFQVTKALKRSKPgAVTTLEQYITIYEALEM
|.. |.. .|| .. .|... . |.. .. |||..|||| |.|.|. .|. . ... |. ..... . ... .| .|.. .|. .|| ..
qylhipipDhgvpdllehflefv.efieealdekggpvlVHCsaGvgRsgtlvaaylmkkl....gl.sleeaielvrerRp.ivpnpgqlrqLyefelr
YLAIN
.|. .
llkes
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 1334-1401 | 3.3e-10 | 33.8 | In-house | 86-155 (349) | alignment | ||
Range on Protein: 1334-1401
Range on HMM: 86-155/349.0
GVAQHEYINASYIH--GYSKARKFIAAQGPMKKTLVDFWCLIWQEKPASVVMLTNLVEDSKTKCEQYWPQ
. ..|||| |.. .| .|.|| | |. |. ||. .| .. |. |.. | | ||..|| .
sgklddyinanylkltrisvekkyiatqaPlPstvddfykvillngvklvlsLnddkelslekcdiywqe
|
|||||||||
0048076 | (Phosphotyrosine protein) phosphatases II | 1407-1488 | 1e-09 | 33.8 | In-house | 11-92 (145) | alignment | ||
Range on Protein: 1407-1488
Range on HMM: 11-92/145.0
EQFGPFSvTLLEDYVMPDYVIRNISVTLQDGSGEVHALTQYHLTTWPDHGVPEYATPLMTLHKRVMSSSA-KGPILVHCSAGW
.|.. | |. . |. |. . . ..... .||. . |||||||. . |... . . . . .||.|||||||
lylgslp.taldlellkdlgittvlnltselellerlgiqylylpwpDhgvpdllellleflefieealkeggpvlVHCsaGv
|
|||||||||
subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 1526-1587 | 1.3e-09 | 32.5 | In-house | 134-197 (198) | alignment | ||
Range on Protein: 1526-1587
Range on HMM: 134-197/198.0
GGPIVVHCSDTVSRTGVYCAISIALE---QCKaEGVVDVFQVTKALKRSKPGAVTTLEQYITIYE
|..||||| |||. |. | . . | |||.|.|.| |.... | ...|..| ||.
dapvivhcsdgqgftgvfvaldigvrsheesk.tsvvdlfevakrlrqarcgiisslqhynfiyq
|
|||||||||
subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 1526-1587 | 1.4e-09 | 32.5 | In-house | 135-198 (199) | alignment | ||
Range on Protein: 1526-1587
Range on HMM: 135-198/199.0
GGPIVVHCSDTVSRTGVYCAISIALE---QCKaEGVVDVFQVTKALKRSKPGAVTTLEQYITIYE
|..||||| |||. |. | . . | |||.|.|.| |.... | ...|..| ||.
dapvivhcsdgqgftgvfvaldigvrsheesk.tsvvdlfevakrlrqarcgiisslqhynfiyq
|
|||||||||
subfamily_Sponge-PTP-7_pd | Subfamily Sponge-PTP-7 | 1529-1590 | 1.4e-09 | 32.2 | In-house | 1-62 (69) | alignment | ||
Range on Protein: 1529-1590
Range on HMM: 1-62/69.0
IVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQYITIYEALE
.||||| ||| . || . . . |.| .||.| . ... .| | .|| |..||
mvvhcssgtgrtgtfiaimvemarikseklvdifnnvqymrkcrpmmvmneieyifihdalv
|
|||||||||
subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 1494-1590 | 1.7e-09 | 31.7 | In-house | 189-280 (290) | alignment | ||
Range on Protein: 1494-1590
Range on HMM: 189-280/290.0
QVIGWMNDGVLRDPRTVLQVIDDVihrqqKIGGGPIVVHCSDTVSRTGVYCAISIALeQCKAEG-VVDVFQVTKALKRSKPGAVTTLEQYITIYEALE
... | . | ..|... . . ||.||||| . ||| . || ..| |. .| .|. .. .||..|. ..| ||... |.|
kikswpdksvalstlallrtlril.....rkasGpvvvhcsaGiGrtGtfvaievgl.qilldGkeldlldlvralrnsrlnsvqvdiqylalveill
|
|||||||||
fn3 | Fibronectin type III domain | 1065-1132 | 2.3e-09 | 30.4 | Pfam-A | 1-76 (85) | alignment | ||
Range on Protein: 1065-1132
Range on HMM: 1-76/85.0
DPPNNVTGFVINTNSIKVNWTNS----TETNGYVIEYTTGGGTR--NVVSTSEDE--IVLTNLSPMSTYTISVYSY
..| |.. ....|. ..|. . . || .|| . ||.. . ....... .||.| | ..|...|...
saPenlsvsevtstsltlsWsppkdgggpitgYeveyrekgggeewkeftvprtttsvtltgLkpgteYefrVqav
|
|||||||||
subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 1307-1457 | 2.3e-09 | 31.3 | In-house | 92-235 (244) | alignment | ||
Range on Protein: 1307-1457
Range on HMM: 92-235/244.0
LNGMNKPLNRFRNIVPYDDNIITLKLpGVAQHEYINASYIHGYSKARKFIAAQGPMKKTLVDFWCLIWQEKPASVVMLTNlVEDSktkcEQYWPQClNEI
.| | || .|.| | . | | |||||.. .. ..| .| |. | .||| .. . . .|.| ||. ..|||. . .
fnpnnswknregaglpfdfnrvplsk.gsmgntyinasfvgclgrtaeyiltqhpladtsmdfwkmmlerhvnvlvvlgs.veee....deywpds.epl
EQFG-PFSVTLLEDYVMPDYVIRNISVTlQDGSGEVHALTQYHLTTWPDHGV
| . .||| . . . |. . | ||| . .. || |
ewyeeditvtltdrdefknikasnleie.sdmneshqaltmfqisnwpsdgt
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 1490-1595 | 3.7e-09 | 30.8 | In-house | 217-346 (350) | alignment | ||
Range on Protein: 1490-1595
Range on HMM: 217-346/350.0
IVQFQVIGWMNDGVLRDPRTVLQVID---DVIH----R--QQKIGGGPIVVHCSDTVSRTGVYCAISIALE------Q---------CKAEgVVD-VFQV
. |.|| | . ..| .|. .||... |.| . .. . ||.|||| | |||..... |. . |. . | ....
vyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaak.trDlisii
TKALKRSKPGAVTTLEQYITIYEALEMYLAI
. |.. . | .|.|.| ||||| | |.
vnelrkqrismvqnldqfifiYeallfyfaL
|
|||||||||
0048179 | (Phosphotyrosine protein) phosphatases II | 1436-1489 | 7.2e-09 | 31.0 | In-house | 41-95 (144) | alignment | ||
Range on Protein: 1436-1489
Range on HMM: 41-95/144.0
DGSGEVHALTQYHLTTWPDHGVPEYATPLMTLHKRVMSS-SAKGPILVHCSAGWN
. . . .||. . |||||||.... | .. . . . . .||.||||||| .
epefleregiqylhlpwpDhgvpdllellleflefieealeeggpvlVHCsaGvg
|
|||||||||
subfamily_Sponge-PTP7_pd | Subfamily Sponge-PTP7 | 1530-1590 | 8.2e-09 | 29.7 | In-house | 1-61 (69) | alignment | ||
Range on Protein: 1530-1590
Range on HMM: 1-61/69.0
VVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQYITIYEALE
||||| ||| . || . . . |.| .||.| . ... .| | ..|. |..||
vvhcssGtGrtGtfiaimvemarikseklvdifnnvqymrkcrpmmvmneneymfihdalv
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 1480-1596 | 1.7e-08 | 28.2 | In-house | 210-347 (349) | alignment | ||
Range on Protein: 1480-1596
Range on HMM: 210-347/349.0
ILVHCSAGWNIVQFQVIGWMNDGVLRDPRTVLQV-------IDDVIHRQ--QKIGGGPIVVHCSDTVSRTGVYCAISIALE--QCKAEG--VV-------
||. . . ..|.|| |.. ..| .| ..|| ||| |. .. ...|||| ||||.. . . |. . . .
illavekPyellqlqvknwldlslllnPisilqalevkndliddlfarlyldtdqlstllvhcsaGcGrtGvlvtldlllsileplqnesnkiklqallk
-DVFQVTKALKRSKPGAVTTLEQYITIYEALEMYLAIN
.. . |.. . | | |.|.||||| |.|..
DlisiivnelrkqrismvqnlaqfiaiyealLkyfalk
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 1440-1487 | 3.7e-08 | 27.1 | In-house | 87-137 (440) | alignment | ||
Range on Protein: 1440-1487
Range on HMM: 87-137/440.0
EVHALTQYHLTTWPDHGVPEYATPLMTLHKRVMSSS---AKGPILVHCSAG
| ..| ||| |||.|||..| |.. . . | | ..||.|||||||
esrtlkqyhyqgwpdkgvpkfagpvlkmiqdvnesqekagngpllvhcsag
|
|||||||||
subfamily_PTPN1_pd | Subfamily PTPN1 | 1489-1588 | 8.8e-08 | 26.2 | In-house | 163-266 (290) | alignment | ||
Range on Protein: 1489-1588
Range on HMM: 163-266/290.0
NIVQFQVIGWMNDGVLRDPRTVLQVIDDVIHRQQ-KIGGGPIVVHCSDTVSRTGVYCAISIALEQCKAEGV---VDVFQVTKALKRSKPGAVTTLEQYIT
.|..| . | . || . | . |. . .| . . || |.||| . |.| .| . | . .... ||. .| .|.. . | . | .|
eilhfhyttwpdfgvpespaaflkflfkvresGslssdvGpavihcsaGiGrsGtfclvdtclvliekkddlssvdikkvllelrkyrlGliqtadqlrf
IYEA
| |
syla
|
|||||||||
subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 1497-1595 | 1.1e-07 | 26.2 | In-house | 180-273 (288) | alignment | ||
Range on Protein: 1497-1595
Range on HMM: 180-273/288.0
GWMNDGVLRDPRTVLQVIDDViHRQQKigggPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQYITIYEALEMYLAI
| .||| . . |.... . . || |||||.| | ||| | ||||. . . . . .. . |. .. |..| ||. .. . .|..
eWdddgvPenylsplrllevl.kslqk....PivvhssaGvGrtgtlililialeslrlddflgirsllaklreerfkaiqtemqylyvhrcvleelll
|
|||||||||
subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 1494-1586 | 1.3e-07 | 26.1 | In-house | 164-252 (290) | alignment | ||
Range on Protein: 1494-1586
Range on HMM: 164-252/290.0
QVIGWMNDGVLRDPRTVLQVIDDVIHRQqkiggGPIVVHCSDTVSRTGVYCAISIALEQCK-AEGVVDVFQVTKALKRSKPGAVTTLEQYITIY
.. || . | .|..|.|..|. | .. |..||| | .|| . || .. .| | . .| |||.. . |.|. ... .
llkgWnklnvqedtktllsliqkvkask.....tpvivHcvdGiSrsAalaaiilgyQkiaetsgsvkledvlkalrkqralaitsalelafvd
|
|||||||||
subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 1496-1584 | 1.3e-07 | 25.4 | In-house | 196-279 (302) | alignment | ||
Range on Protein: 1496-1584
Range on HMM: 196-279/302.0
IGWMNDGVLRDPRTVLQVIDDVIHRQQKigggpIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQYIT
.| . | ... | |... ... ..|||| | ||| || .. |. . | |. .. . ... . ||| . .| |
sawpdhGapkeaytaldilkfcesykkn.....vlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqdeqqliy
|
|||||||||
subfamily_Cele-PTP-12_pd | Subfamily Cele-PTP-12 | 1311-1395 | 2.6e-07 | 24.4 | In-house | 34-118 (332) | alignment | ||
Range on Protein: 1311-1395
Range on HMM: 34-118/332.0
NKPLNRFRNIVPYDDNIITLKlPGVAQHEYINASYIHGYSKARKFIAAQGPMK-KTLVDFWCLIWQEKPASVVMLTNLVEDSKTKC
| .|| . .| . . | | . .. |||.. |||| .| || |.. .| || .. . ||. .... .. | | |.
nmdmnriphlycfdhsrvela.pqdgkddfynaswvdgyskksayifaqapfndhteyvfwrmvserkpsmilvfgdidekqkrka
|
|||||||||
subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 1490-1593 | 8e-07 | 23.4 | In-house | 178-277 (307) | alignment | ||
Range on Protein: 1490-1593
Range on HMM: 178-277/307.0
IVQFQVIGWMNDGVLRDPRTVLQVIDDVihrqqKIGGGPIVVHCSDTVSRTGVYCAISIALEQC-KAEGVVDVFQVTKALKRSKPGAVTTLEQYITIYEA
| ..| | . || . | . ... | . |.||||| | |.| |||. .. . . |. .. . |. .. |. | ||. ..
iqhlqwenwpdrgvpqinltainlleav.....rydtnpvvvhcsaGvGrsGtivaislvqdkmiaGinckdmkklveelrsqrhyaiqteaqylylhrv
LEMYL
| |.
lleyf
|
|||||||||
subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 1311-1475 | 1.1e-06 | 22.3 | In-house | 51-214 (302) | alignment | ||
Range on Protein: 1311-1475
Range on HMM: 51-214/302.0
NKPLNRFRNIVPYDDNIITLKlpgVAQHEYINASYIHGYSKARKFIAAQGPMKKTL---VDFWCLIWQEKPASVVMLTNLVEDSKtKCEQYWPQCLNEIE
| |. .. .|.|.. |. .. .|.||| .. . |. | || | ... .|| ...||| .|||.| | .| ....|. .. .
nlkknqsedvpildsnlvkle...aepdsyvnaskvevPeltrsiilaQlpkvdsedsveeFWrmvfqekivsvvilvgeeelkk.tlselfpkksgdyk
QFGPFSVTLLEDYVMPDYVIRNISVTLQDGSGEVHALTQYHLTTWPDHGVPEYATPLMTLHKRVMSSS
..| . | . . . | . | .| . . |.|| |... ||. . |.. . | ..
eygkmfvNnrkVekaeeektryviEvlPegcsnsvlanvyvltnWkqkkvpvkyaeliktaakvfakk
|
|||||||||
subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 1518-1589 | 2e-06 | 21.6 | In-house | 192-265 (281) | alignment | ||
Range on Protein: 1518-1589
Range on HMM: 192-265/281.0
IHRQQKIGGGPIVVHCSDTVSRTGVYCAISIALEQCKAE-GVVDVFQVTKALKRS-KPGAVTTLEQYITIYEAL
| |. . | |.||| | |.| |. |||. .. . |. |. |. . . .| ||.||. |.. |
ilrkirarstppvihcsagvgrsgtlmaveialqsihshftlpdikqivshlrvtgraasvqtlqqymliwkvl
|
|||||||||
subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 1314-1463 | 3.4e-06 | 20.9 | In-house | 50-192 (303) | alignment | ||
Range on Protein: 1314-1463
Range on HMM: 50-192/303.0
LNRFRNIVPYDDNIITLklpgvAQHEYINASYIHGYSkARKFIAAQGPMKKTLVDFWCLIWQEKPASVVMLTNLVEDSKTKCEQYWPQCLNeIEQFGPFS
||| ... | . | .. || |||.. | .| | .| |. .| ||| .| ..| |..| | | . .|. . . .| |
knrfvdvicldhskvkl.....sdssyihasylelds.skkailtqlplshtaadfwqmiieqkvkcvlllltdseydklggdsvfprnqd.flkfeers
VTLLE---DYVMPDYVIRNISVTLQDGSGEVHAltqYHLTTWPDHGVPEYATP
. . | .. .|.. .||. | .| .| .|| .| ..|
irvgefkrvelgdgwvlkvlsvsngdyksflhv...hhykawphnsipsdgsp
|
|||||||||
subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 1524-1587 | 4.7e-06 | 20.4 | In-house | 221-284 (310) | alignment | ||
Range on Protein: 1524-1587
Range on HMM: 221-284/310.0
IGGGPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQYITIYE
. || ||||| . |..| .|. ..... . ||. .| |..|. . | ||. |
vrhgpcvvhcsagkdrlyvvvalklkidkldrglkvdaeevktellksraiciqtelqyliidr
|
|||||||||
subfamily_Sponge-PTP-4_pd | Subfamily Sponge-PTP-4 | 1334-1456 | 4.8e-06 | 20.9 | In-house | 9-125 (130) | alignment | ||
Range on Protein: 1334-1456
Range on HMM: 9-125/130.0
GVAQHEYINASYIHGYSKARKFIAAQGPMKKTLVDFWCLIWQEKPASVVMLTnLVEDSktkcEQYWPQClNEIEQFGPFSVTLLEDYVMPDYVIRNISVT
. ...|||||.. ...... .| |. .| .||| .. . .|.| ||. ..|||. . .| . . | | ... .
rlqgntyinasfvGllgrtaeylltqhpladtsmdfwkmmleryvnvlvvlg.sveee....deywpds.ePlewyeediivtltdrdefknikasnlei
LQDGSGEVHALTQYHLTTWPDHG
.| .||| .... || |
esdlneshqaltmfqisnwpsdg
|
|||||||||
subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 1497-1594 | 7.9e-06 | 19.5 | In-house | 190-286 (302) | alignment | ||
Range on Protein: 1497-1594
Range on HMM: 190-286/302.0
GWMNDGVLRDPRTVLQVIDDViHRQQKIGGGPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVDVFQVTKALKRSKPGAVTTLEQYITIYEALEMYLA
| .. |. .. . . .| . .. . ..|. . | |. . .|.|. ... . . .. |... .| || .|.||...| || .|.
nWkqkkvpvkyaeliktaakv.fakkikadentvivSknGaGRagafltlavaveklqkgkepnikeivksiRsqRpravdslkQyvslyialllyik
|
|||||||||
subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 1492-1591 | 8.2e-06 | 19.8 | In-house | 190-285 (305) | alignment | ||
Range on Protein: 1492-1591
Range on HMM: 190-285/305.0
QFQVIGWMNDGVLRDPRTVLQVIDDVihrqqKIGGGPIVVHCSDTVSRTGVYCAISIALEQCKAEGVVD-VFQVTKALKRSKPGAVTTLEQYITIYEALE
.. | | . || ..|... . . |||||||| . ||| . |.| | ... .. . .. . .. | .||. ... .
hyhwidwpdrgvpaadlailelleka.....rpskgpivvhcsagigrtgsvvmleyildqllagqiiedtdkilqkireqrnnsiqtdaqylfvhqvil
M
n
|