Gene PTPRD-72 in Amphimedon queenslandica

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family PTP
Subfamily PTPRD
Protein sequence
ID Type Fasta BLAST phosphatome Note
AqueP131_AA protein Get Run
AqueP131_AA_1447-1506 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_Sponge-PTP9_pd Subfamily Sponge-PTP9 1445-1513 2e-42 139.9 In-house 233-301 (301) alignment 
Range on Protein: 1445-1513
Range on HMM: 233-301/301.0
INDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRTKPGAVTTLEQYTSIYDVIDMYFKLHSTYAN
  ||||||||||||||.||||||||||||||||||.||.|||||||||||||||||||||..|.|||||
CSdtVsrsGvYcsvsiglEQckaegVVdvfqvtkavrrskpgaVtTLeqytsiydvidmylqlnstyan
subfamily_Sponge-PTP8_pd Subfamily Sponge-PTP8 1441-1507 3.5e-25 83.8 In-house 219-285 (305) alignment 
Range on Protein: 1441-1507
Range on HMM: 219-285/305.0
IIAFINDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRTKPGAVTTLEQYTSIYDVIDMYFKL
..   ...|.|.||...|.||||..|.|.|||||.|.|..|......|.||.||....|..| . . 
llVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkmvqtldqYvflhdaldelitc
subfamily_Sponge-PTP11_pd Subfamily Sponge-PTP11 1446-1511 3.3e-19 63.8 In-house 224-289 (290) alignment 
Range on Protein: 1446-1511
Range on HMM: 224-289/290.0
NDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRTKPGAVTTLEQYTSIYDVIDMYFKLHSTY
 |||.||.|.|.. .....|| |||.||||| |  |  ||| |.| .||  |....  |..  .||
SdtvgrsavfcaaattinkcktegvidvfqvlksqRiqkpgsvqtvqqyqgifqivltyldsfety
subfamily_Sponge-PTP10_pd Subfamily Sponge-PTP10 1441-1514 1.4e-17 58.7 In-house 214-287 (287) alignment 
Range on Protein: 1441-1514
Range on HMM: 214-287/287.0
IIAFINDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRTKPGAVTTLEQYTSIYDVIDMYFKLHSTYANF
|.    ||| ||...|.. .....|| |||.||||| |  |  |||.| | |||. |.|.. .| .  .||..|
ivvhCsdtvGrsamfcaaattinkckteGviDvfqvlksqriqkpgsvqtveqykfindivleyldsfetysdf
subfamily_Anemone-PTP-2_pd Subfamily Anemone-PTP-2 1446-1512 3e-16 54.5 In-house 231-297 (298) alignment 
Range on Protein: 1446-1512
Range on HMM: 231-297/298.0
NDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRTKPGAVTTLEQYTSIYDVIDMYFKLHSTYA
 . | ||| .. ..  ||. |.| ||||||| |..|...||||.| |||. ||...  ...  ....
saGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavlealdsfndei
subfamily_Nvec-PTP-2_pd Subfamily Nvec-PTP-2 1445-1512 1.4e-15 52.2 In-house 182-249 (250) alignment 
Range on Protein: 1445-1512
Range on HMM: 182-249/250.0
INDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRTKPGAVTTLEQYTSIYDVIDMYFKLHSTYA
    |.||| .. ..  ||. | | |||||.| |..|. .|.||..|||| ..| .|  . .  . ||
CsaGvgrsGafiaidavlerlkkekvvdvfkvikvlrkdrphavesleqyvfvyeiilkaldsvedya
subfamily_CG7180_pd Subfamily CG7180 1442-1504 7.2e-15 49.4 In-house 227-289 (296) alignment 
Range on Protein: 1442-1504
Range on HMM: 227-289/296.0
IAFINDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRTKPGAVTTLEQYTSIYDVIDMY
.   .| .||||||... ..||. . |. ||||.  | .|| .|. | . |.|  ||||.  .
vvvssdGasRsGvylaidanlelvekeeevdvFeavktlrrsRpqLvenveeYkyiYdvllea
subfamily_PTPRD_pd Subfamily PTPRD 1449-1511 3e-14 47.6 In-house 225-287 (564) alignment 
Range on Protein: 1449-1511
Range on HMM: 225-287/564.0
VSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRTKPGAVTTLEQYTSIYDVIDMYFKLHSTY
| |.|... ... ||. |.|..||..|. ||.|. ..  | | |||  |...|  . .  .| 
VGRTGtfividamlerikeektvDiyqyvkalrkqRnamVqteeQYiFiheailealacgnte
subfamily_Anemone-PTP-6_pd Subfamily Anemone-PTP-6 1444-1513 5.8e-14 46.9 In-house 219-288 (318) alignment 
Range on Protein: 1444-1513
Range on HMM: 219-288/318.0
FINDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRTKPGAVTTLEQYTSIYDVIDMYFKLHSTYAN
     | | ||.. |.| ||. |||..|||||. | .|. ..  | | .||. ||||.  . .   |...
hCsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqtedqyefiydvllealasgdtevd
subfamily_Anemone-PTP-5_pd Subfamily Anemone-PTP-5 1445-1511 1.5e-13 45.5 In-house 223-289 (319) alignment 
Range on Protein: 1445-1511
Range on HMM: 223-289/319.0
INDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRTKPGAVTTLEQYTSIYDVIDMYFKLHSTY
  . | | | .. ....||. | |||.|||.. . .|  ..  | . |||. ||...  . .  .| 
CsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyealleaveagdte
0050432 (Phosphotyrosine protein) phosphatases II 1449-1513 2.8e-13 45.4 In-house 243-307 (308) alignment 
Range on Protein: 1449-1513
Range on HMM: 243-307/308.0
VSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRTKPGAVTTLEQYTSIYDVIDMYFKLHSTYAN
|.|.|... . ..||| ..|| ||||.. | .|. .||.|.|.|||  .|... .|.||. |..|
vGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylflyralleylklkltkln
Y_phosphatase Protein-tyrosine phosphatase 1448-1501 7e-13 43.9 Pfam-A 180-233 (235) alignment 
Range on Protein: 1448-1501
Range on HMM: 180-233/235.0
TVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRTKPGAVTTLEQYTSIYDVI
 |.|.|......|.|||..||. |||.|. | .|. .||.|..||||  .|..|
GvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmvqsleqYiflykai
Y_phosphatase Protein-tyrosine phosphatase 1448-1501 7e-13 43.9 In-house 180-233 (235) alignment 
Range on Protein: 1448-1501
Range on HMM: 180-233/235.0
TVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRTKPGAVTTLEQYTSIYDVI
 |.|.|......|.|||..||. |||.|. | .|. .||.|..||||  .|..|
GvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmvqsleqYiflykai
0046845 (Phosphotyrosine protein) phosphatases II 1449-1513 2e-12 42.6 In-house 215-282 (284) alignment 
Range on Protein: 1449-1513
Range on HMM: 215-282/284.0
VSRSGVYCSVSIALEQCKAEG---VVDVFQVTKAIRRTKPGAVTTLEQYTSIYDVIDMYFKLHSTYAN
|.|.|... . ..||| ..||   .|||... | .|. .||.|.|||||  .|... .|.||. |...
vgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleylklkltlle
0036941 (Phosphotyrosine protein) phosphatases II 1449-1510 4.6e-12 41.3 In-house 218-282 (297) alignment 
Range on Protein: 1449-1510
Range on HMM: 218-282/297.0
VSRSGVYCSVSIALEQCK---AEGVVDVFQVTKAIRRTKPGAVTTLEQYTSIYDVIDMYFKLHST
|.|||... . ..|.| .    || ||.... | .|. .||||.|||||  .|... ...| . |
vgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallellkkklt
fn3 Fibronectin type III domain 275-342 5e-12 39.0 Pfam-A 9-79 (85) alignment 
Range on Protein: 275-342
Range on HMM: 9-79/85.0
VNKTATTITVSWTALD--SSDADGYVVNITSDTDT--VQTVQVEGSNNnTITLNGLRGGTTYSITVRAYQQL
 . |.|..|.||.. .  ... .|| |   .....   ....|... . . ||.||. ||.|...|.|. . 
sevtstsltlsWsppkdgggpitgYeveyrekgggeewkeftvprttt.svtltgLkpgteYefrVqavnga
0040438 (Phosphotyrosine protein) phosphatases II 1449-1511 6.3e-12 40.8 In-house 220-282 (317) alignment 
Range on Protein: 1449-1511
Range on HMM: 220-282/317.0
VSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRTKPGAVTTLEQYTSIYDVIDMYFKLHSTY
|.|.|... . ..|||.. || |||... | .|. .||||.|.|||  .||.. .|.| . |.
vgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleylkrkltl
subfamily_PTPRA_pd Subfamily PTPRA 1445-1506 7.6e-12 39.7 In-house 235-296 (330) alignment 
Range on Protein: 1445-1506
Range on HMM: 235-296/330.0
INDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRTKPGAVTTLEQYTSIYDVIDMYFK
    | |.| .. ..  ||. |||..||||.. | .|  .|  | |.|||. || |.  |. 
csaGvGrtGtfivldavlervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvlleyyl
subfamily_PTPRK_pd Subfamily PTPRK 1448-1501 8.6e-12 39.5 In-house 220-273 (314) alignment 
Range on Protein: 1448-1501
Range on HMM: 220-273/314.0
TVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRTKPGAVTTLEQYTSIYDVI
   |.|... ..| |.  . |||||||.. |..| .|.  | | |||. |||||
GaGrtGtfiaidivldmieregvvdvfnavktlrsrkvnmveteeqykfiydvi
0051299 (Phosphotyrosine protein) phosphatases II 1449-1505 8.7e-12 40.5 In-house 230-286 (288) alignment 
Range on Protein: 1449-1505
Range on HMM: 230-286/288.0
VSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRTKPGAVTTLEQYTSIYDVIDMYF
|.|.|... . ..||| ..||.|||... | .|. .||.|.|.|||  .|... .|.
vgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyealleyl
DSPc_SM00195 1449-1506 8.8e-12 40.3 In-house 206-263 (263) alignment 
Range on Protein: 1449-1506
Range on HMM: 206-263/263.0
VSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRTKPGAVTTLEQYTSIYDVIDMYFK
|.|.|......|.|.....|  ||.|.. |..|  .||.|.|||||. ||..|  |.|
vgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyik
PTPc_SM00194 1449-1506 8.8e-12 40.3 In-house 206-263 (263) alignment 
Range on Protein: 1449-1506
Range on HMM: 206-263/263.0
VSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRTKPGAVTTLEQYTSIYDVIDMYFK
|.|.|......|.|.....|  ||.|.. |..|  .||.|.|||||. ||..|  |.|
vgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyik
0047943 (Phosphotyrosine protein) phosphatases II 1449-1505 3.7e-11 38.5 In-house 216-272 (273) alignment 
Range on Protein: 1449-1505
Range on HMM: 216-272/273.0
VSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRTKPGAVTTLEQYTSIYDVIDMYF
|.|.|... . ..|.| ..|| |||... | .|. .||.|.|.|||  .|... .|.
vgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyealleyl
0039614 (Phosphotyrosine protein) phosphatases II 1449-1508 4.9e-11 38.1 In-house 233-292 (297) alignment 
Range on Protein: 1449-1508
Range on HMM: 233-292/297.0
VSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRTKPGAVTTLEQYTSIYDVIDMYFKLH
|.|.|...   ..|||.. || |||... | .|. .||||.|..||  .||.. ...| .
vgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydallellkrk
subfamily_Urchin-PTP-7_pd Subfamily Urchin-PTP-7 1441-1502 5.2e-11 37.0 In-house 215-276 (315) alignment 
Range on Protein: 1441-1502
Range on HMM: 215-276/315.0
IIAFINDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRTKPGAVTTLEQYTSIYDVID
|.   .. | |.| .....  |.| .|| ..||... . .|. . ..| ..|||  |||.. 
ivvhcsaGvGrtGtfitldavldqaeaenaidvynfitgvrqnrikmvqvaeqyqfiydall
fn3 Fibronectin type III domain 1056-1145 1.6e-10 34.2 Pfam-A 1-85 (85) alignment 
Range on Protein: 1056-1145
Range on HMM: 1-85/85.0
SPVTSLSVSNVSTTGITVNWTIP-SSDDYLTYCTISYtSSCPQLSsVNETVSVAPHqsttTYSYTLIGLYSGMNYTITVRAGNVLGGSDPS
|... ||||.|..| .|..|. | . .. .|. .. | ... . . .  ...| ..    |.|.|| ||  |..|...|.| |  |.. .|
saPenlsvsevtstsltlsWsppkdgggpitgYevey.rekggge.ewkeftvprt....ttsvtltgLkpgteYefrVqavngagegpeS
PTPc_DSPc_SM00012 1449-1501 1.8e-10 36.3 In-house 50-103 (105) alignment 
Range on Protein: 1449-1501
Range on HMM: 50-103/105.0
VSRSGVYCSVSIALEQCKAE-GVVDVFQVTKAIRRTKPGAVTTLEQYTSIYDVI
|.|.|... ..|.|.|...| . ||.||. |..|. .||.|.|.|||  .|...
vgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylflyral
subfamily_Sponge-PTP5_pd Subfamily Sponge-PTP5 1444-1501 2.9e-10 34.5 In-house 205-262 (283) alignment 
Range on Protein: 1444-1501
Range on HMM: 205-262/283.0
FINDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRTKPGAVTTLEQYTSIYDVI
    .. |..|....| .... ..| |||||.| | .|  ...|| ||.||  .....
hCstgiGrtavfiaasasvkdaltesvvdvfavvkimreqrmmavqtldqyklvhelv
subfamily_Urchin-PTP-1_pd Subfamily Urchin-PTP-1 1442-1509 3e-10 34.5 In-house 214-281 (315) alignment 
Range on Protein: 1442-1509
Range on HMM: 214-281/315.0
IAFINDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRTKPGAVTTLEQYTSIYDVIDMYFKLHS
.      | |.|| .|.   ..| | . .||||.. | .|. .|  | | |.|. |||..  ... . 
lvhcsaGvGrtGvvisidevvaqikrtrsvdvfnfvknlrakrpylvqteeeyafiydavledllwrn
0043336 (Phosphotyrosine protein) phosphatases II 1449-1505 3.8e-10 35.2 In-house 221-277 (278) alignment 
Range on Protein: 1449-1505
Range on HMM: 221-277/278.0
VSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRTKPGAVTTLEQYTSIYDVIDMYF
|.|.|... . ..||| . || ||.... | .|. .||||.|..||  .|... .|.
vgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyealleyl
subfamily_PTPRG_pd Subfamily PTPRG 1445-1501 5.1e-10 33.2 In-house 227-283 (563) alignment 
Range on Protein: 1445-1501
Range on HMM: 227-283/563.0
INDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRTKPGAVTTLEQYTSIYDVI
 .  |.|.|.|. ..  |.| ..| .|.||.. | ||  ..  |.| |||. ..|..
csaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvqteEqYiflhdal
subfamily_Urchin-PTP-6_pd Subfamily Urchin-PTP-6 1443-1507 1e-09 32.0 In-house 214-278 (515) alignment 
Range on Protein: 1443-1507
Range on HMM: 214-278/515.0
AFINDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRTKPGAVTTLEQYTSIYDVIDMYFKL
      | | ||..|.   . . |   .||||.. . ||. .|  | | |||. ||...  ... 
ihcsaGvGrtGvvisidsvvahakttrmvdvfnfvtnirqkrpylvqtqeqyafiygavledllw
0045450 (Phosphotyrosine protein) phosphatases II 1449-1505 1.2e-09 33.8 In-house 245-304 (307) alignment 
Range on Protein: 1449-1505
Range on HMM: 245-304/307.0
VSRSGVYCSVSIALEQCKAEGV---VDVFQVTKAIRRTKPGAVTTLEQYTSIYDVIDMYF
|.|.|...   ..|.| ..||.   ||.... | .|. .||||...|||  .|... ...
vgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeallell
0042113 (Phosphotyrosine protein) phosphatases II 1449-1505 2.6e-09 32.4 In-house 187-243 (245) alignment 
Range on Protein: 1449-1505
Range on HMM: 187-243/245.0
VSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRTKPGAVTTLEQYTSIYDVIDMYF
|.|.|... . ..||| ..|. |..... | .|. .||||.|..||  .|... ...
vgRtGtfiaaylmleqlekelgvsleeavkelrsqRpgavqtpsqyrflyeallell
0040439 (Phosphotyrosine protein) phosphatases II 1449-1505 2.8e-09 32.5 In-house 190-246 (249) alignment 
Range on Protein: 1449-1505
Range on HMM: 190-246/249.0
VSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRTKPGAVTTLEQYTSIYDVIDMYF
|.|.|...   ..||| . |. ||.... | .|. .||||...|||  .|... ...
vgRtGtfiaaylmleqlekelgvdleeavkllrsqRpgavqnpeqyrflyeallell
subfamily_Ptp69D_pd Subfamily Ptp69D 1446-1504 3e-09 31.4 In-house 227-285 (307) alignment 
Range on Protein: 1446-1504
Range on HMM: 227-285/307.0
NDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRTKPGAVTTLEQYTSIYDVIDMY
.  |.|||.. .... |.|.|||  ||.|...| .|. ..  |. ||||. .|  .  |
saGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnllvqsleqYvflyralldy
subfamily_PTPN5_RR_pd Subfamily PTPN5_RR 1448-1506 6.1e-09 30.4 In-house 211-269 (274) alignment 
Range on Protein: 1448-1506
Range on HMM: 211-269/274.0
TVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRTKPGAVTTLEQYTSIYDVIDMYFK
 . | |.. ..|||. | ..|.||||....  .|  . | | | |||  |. .. .| |
GiGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralclylk
subfamily_Urchin-PTP-5_pd Subfamily Urchin-PTP-5 1447-1505 8.9e-09 29.9 In-house 226-284 (297) alignment 
Range on Protein: 1447-1505
Range on HMM: 226-284/297.0
DTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRTKPGAVTTLEQYTSIYDVIDMYF
  | | ||....   . . | |  ||.|.. | .|. .|  | | |||. .| ..  ..
aGvGrtgvlltidsvvaeakrekevdifglvkklrqerpylvqtkeqykfvyvavleal
fn3 Fibronectin type III domain 1253-1344 9.2e-09 28.5 Pfam-A 8-84 (85) alignment 
Range on Protein: 1253-1344
Range on HMM: 8-84/85.0
VSSImDTTWAVISWSIPIyiPSDYPIITYEIGYHALESGNcsmvyddditpqVLNLFNVSSNNTFTTITGLNSNTCYILGVHAYSDNGYGAW
||..  .| ...||| |   . . ||  ||. |   ..|.            . . |.|... |  |.|||. .| | . |.|....|.| .
vsev.tstsltlsWsppk..dgggpitgYeveyrekggge............ewkeftvprtttsvtltgLkpgteYefrVqavngagegpe
fn3 Fibronectin type III domain 1172-1236 1.2e-08 28.1 Pfam-A 18-85 (85) alignment 
Range on Protein: 1172-1236
Range on HMM: 18-85/85.0
FTWNEVNcsERNGLITSYTVMISNS-----SITYNLTSTERHIILNDLVFGTEYNISVAAVNSAGRGSFS
..|.. .  ...| ||.|.|  ...     . ......|... .|..|  ||||...|.||| || | .|
lsWsppk..dgggpitgYeveyrekgggeewkeftvprtttsvtltgLkpgteYefrVqavngagegpeS
0045098 (Phosphotyrosine protein) phosphatases II 1449-1506 1.4e-08 29.9 In-house 217-273 (278) alignment 
Range on Protein: 1449-1506
Range on HMM: 217-273/278.0
VSRSGVYCSVSIALEQCkaEGVVDVFQVTKAIRRTKPG-AVTTLEQYTSIYDVIDMYFK
|.|.|... . . ||..  ||.||.... | .|. .|| ||..||||  .|... ....
vgRtGtlvaaylmlell..eggvdlleavkelrsqRpglavqnleqyrflyefllelll
fn3 Fibronectin type III domain 971-1037 1.7e-08 27.6 Pfam-A 2-76 (85) alignment 
Range on Protein: 971-1037
Range on HMM: 2-76/85.0
PPNNVKGFILNATSIKVNWTNS----SEAIGYVIEYTTESVTR--NVVSTSKDE--IVLTDLLPMSTYTISVYSY
.| |..    ..||. ..|. .    ..  || .|| ... ..  . .......   .||.| | ..|...|...
aPenlsvsevtstsltlsWsppkdgggpitgYeveyrekgggeewkeftvprtttsvtltgLkpgteYefrVqav
subfamily_Sponge-PTP1_pd Subfamily Sponge-PTP1 1441-1501 1.7e-08 28.8 In-house 195-255 (267) alignment 
Range on Protein: 1441-1501
Range on HMM: 195-255/267.0
IIAFINDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRTKPGAVTTLEQYTSIYDVI
..   .| | ||| .  .   ||. | |||.|.|.  . ||  ..| | |.|.|  |....
lvvacsdGvGrsGtflvidsqleraktegvsdifdflrkirsqriglvdtkeryiyihell
subfamily_Urchin-PTP-3_pd Subfamily Urchin-PTP-3 1444-1504 3.8e-08 27.8 In-house 227-287 (325) alignment 
Range on Protein: 1444-1504
Range on HMM: 227-287/325.0
FINDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRTKPGAVTTLEQYTSIYDVIDMY
   . | |.||. |.  ||..   |  ||.|.. | .|. .|  | | .||. ||. .  .
hcsaGvGrtGvfislysalakvieesrvdifgfvkklrkdrpsmvetvdqyiliyealvea
subfamily_Urchin-PTP-2_pd Subfamily Urchin-PTP-2 1447-1502 4.2e-08 27.0 In-house 380-435 (440) alignment 
Range on Protein: 1447-1502
Range on HMM: 380-435/440.0
DTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRTKPGAVTTLEQYTSIYDVID
  .  |||.|.|   ||| . .| .||||  . .| ..|  | || .|   | .. 
sgieesgvfctvmncleqlnndgaidvfqnlrllrlsrpnfvptltdyllcykllt
fn3 Fibronectin type III domain 455-523 7e-08 25.7 Pfam-A 2-78 (85) alignment 
Range on Protein: 455-523
Range on HMM: 2-78/85.0
PPNNVRGFILNTTSIKVNWTTS----SETNGYVIEYTTGSVT--RNVISTSEGE--IVLTDLSPMSTYTISVYSYTD
.| |..    ..||. ..|. .    ..  || .|| . . .   . ..... .   .||.| | ..|...|.....
aPenlsvsevtstsltlsWsppkdgggpitgYeveyrekgggeewkeftvprtttsvtltgLkpgteYefrVqavng
subfamily_Urchin-PTPRB-like_pd Subfamily Urchin-PTPRB-like 1441-1501 2.7e-07 24.9 In-house 215-275 (288) alignment 
Range on Protein: 1441-1501
Range on HMM: 215-275/288.0
IIAFINDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRTKPGAVTTLEQYTSIYDVI
||    . | |.|.. ..  .... ..| ..||. . . .|. ..  | ||.||  ||.|.
iivhCsaGvGrtgtFialdalidaveeedyiDvagtvaklRkqRallvqtlkqYefiyevl
subfamily_Urchin-PTP-4_pd Subfamily Urchin-PTP-4 1448-1506 4.6e-07 23.6 In-house 328-386 (392) alignment 
Range on Protein: 1448-1506
Range on HMM: 328-386/392.0
TVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRTKPGAVTTLEQYTSIYDVIDMYFK
   |.||.|.    . |      ||.||  | .|  .   | | |.|. .||||  |..
gagrtgvfctameciaqiaegdsvdifqtvkilradrmqfvqteeeyafvydvireylh
subfamily_Cele-PTP-4_pd Subfamily Cele-PTP-4 1450-1510 8.2e-07 22.7 In-house 230-290 (302) alignment 
Range on Protein: 1450-1510
Range on HMM: 230-290/302.0
SRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRTKPGAVTTLEQYTSIYDVIDMYFKLHST
 | |.  .. .|.|. ...  . . .. |.||  .| || .|.||.|.| .. .|.| . |
GRagafltlavaveklqkgkepnikeivksiRsqRpravdslkQyvslyialllyikkkvt
0037934 (Phosphotyrosine protein) phosphatases II 1449-1505 1e-06 24.0 In-house 189-242 (243) alignment 
Range on Protein: 1449-1505
Range on HMM: 189-242/243.0
VSRSGVYCSVSIALEQCkaeGvVDVFQVTKAIRRTKPG-AVTTLEQYTSIYDVIDMYF
|.|.|...   . |...   | ||.... | .|. .|| ||.|..||  .|... ...
vgRtGtliaaylmllll...g.vdleeavkllreqRpgkavqtpsqyrflyeallell
subfamily_Urchin-PTP-8_pd Subfamily Urchin-PTP-8 1442-1501 2.2e-06 22.4 In-house 192-251 (284) alignment 
Range on Protein: 1442-1501
Range on HMM: 192-251/284.0
IAFINDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRTKPGAVTTLEQYTSIYDVI
.      | |.|||  . . |.. | |  |||... . .|. ..  |  | ||  ||  .
vvhcsagvgrtgvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysal
subfamily_Urchin-PTPRA_pd Subfamily Urchin-PTPRA 1442-1500 2.2e-06 22.2 In-house 228-286 (319) alignment 
Range on Protein: 1442-1500
Range on HMM: 228-286/319.0
IAFINDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRTKPGAVTTLEQYTSIYDV
.      | |.|||  . . |.. | |  |||... . .|. ..  |  | ||  ||  
vvhcsaGvGrtGvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysa
subfamily_PTPN12_pd Subfamily PTPN12 1448-1507 2.5e-06 21.6 In-house 217-279 (290) alignment 
Range on Protein: 1448-1507
Range on HMM: 217-279/290.0
TVSRSGVYCSVSIALEQCKAEGV---VDVFQVTKAIRRTKPGAVTTLEQYTSIYDVIDMYFKL
 | | |. ... .. |. ||| .   .|||..   .|. .. .| | |||. .|  .  ... 
GvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelvqk
subfamily_Anemone-PTP-1_pd Subfamily Anemone-PTP-1 1446-1498 3e-06 21.6 In-house 182-234 (239) alignment 
Range on Protein: 1446-1498
Range on HMM: 182-234/239.0
NDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRTKPGAVTTLEQYTSIY
.  | |.| .  .   | |.| .  ||.|.  ||||  .|  | | |||  |.
sagvgrtgaflvidamlrqakkqktvdifnyvkairedrphmvqtseqyvfih
subfamily_Nvec-PTP-1_pd Subfamily Nvec-PTP-1 1446-1498 3e-06 21.6 In-house 181-233 (239) alignment 
Range on Protein: 1446-1498
Range on HMM: 181-233/239.0
NDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRTKPGAVTTLEQYTSIY
.  | |.| .  .   | |.| .  ||.|.  ||||  .|  | | |||  |.
sagvgrtgaflvidamlrqakkqktvdifnyvkairedrphmvqtseqyvfih
0036282 (Phosphotyrosine protein) phosphatases II 1449-1499 4e-06 22.1 In-house 115-164 (174) alignment 
Range on Protein: 1449-1499
Range on HMM: 115-164/174.0
VSRSGVYCSVSIALEQCKaEGVVDVFQVTKAIRRTKPGAVTTLEQYTSIYD
|.|.|. .   . | . . |..||.... ...|. .||.|.| .||  .|.
vgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtpsQyrflyy
subfamily_CG42327_pd Subfamily CG42327 1445-1506 8.1e-06 19.7 In-house 254-316 (319) alignment 
Range on Protein: 1445-1506
Range on HMM: 254-316/319.0
INDTVSRSGVYCSVSIALEQCKAE-GVVDVFQVTKAIRRTKPGAVTTLEQYTSIYDVIDMYFK
  | | |.|.  .  ||... .     ||. |.   .|| .  || | |||  || |. .| |
csdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefiykvlseyak
0051429 (Phosphotyrosine protein) phosphatases II 1449-1506 8.9e-06 21.1 In-house 161-226 (272) alignment 
Range on Protein: 1449-1506
Range on HMM: 161-226/272.0
VSRSGVYCSVSIALEQCKAEGVVD--------VFQVTKAIRRTKPGAVTTLEQYTSIYDVIDMYFK
..|.|... . . |..  .| .||        .... . .|.  |||| | |||  .|...  ...
kdRTGtvvallllllgvsletivddYlltnlyleeaveelraqrpgavqteeqylflyeallellr