Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
subfamily_PTPRD_pd | Subfamily PTPRD | 1223-1528 | 6e-130 | 429.5 | In-house | 2-309 (564) | alignment | ||
Range on Protein: 1223-1528
Range on HMM: 2-309/564.0
RQSISVSMFPDYVKRLHANTDHLFSEEYELITIKsPSLPHEASQQTCNIEKNRYGNINSFDETRVVLTKIPGIEGSDYINANYIDGYGSRDTYIACQGPL
...|.|. ....|..|.|| | |.|||. |. . .. . ||... .| .|||| || .|..||||.|..| ||||||||..|||| .| .||| ||||
skpipvaelkehvaklkansdlkfeeeykkieeg.qqftweaankpaNkaKNRyanivaYdhsRVvLskvegdegsDYINAsfidgyrkrkayIAtqgPl
AETSPDFWRMIWEQKTSCIVMLTNCVEKGRPKCHQYWPQTGSTTFGELTVTIIDQQVLAYYTIRTFKI-NNKDDESFEVKQFHYTAWPDFGVPDHPNPII
||| |||||.|||..|.|||||...|||. |||.|||..|..|.||||||. ... ||.|.|||||. ..|..|| ||.|||.|.||| |||.......
aetiedFWRmvweqnsstiVmltkleEkgkvkchkYWPekgtetygeltVtleeeeeladyeirtfklkkkkssesreVrqFhFtsWPdhgvpesatslL
SFIRRVNNS--THTGPLVVHCSAGVGRSGTFIAIQSMMLMMETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELIKVGNSEQTVQNFPKEAKIL
..||.|... ...||.||||||||||.||||.|..|. ...|..||....| .|..||.||||| ||.|.|. ..| .. || | ...|. .. . |
dlirkvralnepdagPivVhCSaGVGRTGtfividamlerikeektvDiyqyvkalrkqRnamVqteeQYiFiheailealacgntevesenlkqhlqkL
LTTQEDNNI
...||...
aeveedtem
|
|||||||||
subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 1226-1524 | 3.7e-111 | 366.2 | In-house | 2-304 (318) | alignment | ||
Range on Protein: 1226-1524
Range on HMM: 2-304/318.0
ISVSMFPDYVKRLHANTDHLFSEEYELITIKSPSLPHEASQQTCNIEKNRYGNINSFDETRVVLTKIPGIEGSDYINANYIDGYGSRDTYIACQGPLAET
|||. . . |.||... . |.||||| .. .. . . | . .| |||| || ..|.||| |... | |||||||||||||| .. .|||.|.||.||
isvedleshvrrlresGelllseeyerlsrseetvtslkslepvnkaknryanilaydhtrvkLqmlegeegsDyinanyidGyrrkkayiaaqaPlpet
SPDFWRMIWEQKTSCIVMLTNCVEKGRPKCHQYWPQTGSTTFGELTVTIIDQQVLAYYTIRTFKINNK-DDESFEVKQFHYTAWPDFGVPDHPNPIISFI
.|||||.|||... |||||...|.|. |.|.|||. ||...|.|.|.. .. |..|..|.||.... .|| .|.|.|||.||| |||... .....
ieDfWrmvWeqnsavivmltqeeergkakvhryWPskgsrsygklvvelkeevelsdyvlrefkvtrteeeesrqvrqyhytsWpdegvpesgaslldlv
RRVNNST---HTGPLVVHCSAGVGRSGTFIAIQSMMLMMETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELIKVGNSEQTVQNFPKEAKILLT
|.|.. .||.|||||||||| |.|||..... .. |. ||||..| .|..|| ||||| || |..| |.| .. |..| ... .. . |
rqvskaqqksgagpivvhCsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqtedqyefiydvllealasgdtevdasdlrsrirelre
TQE
..
qdp
|
|||||||||
subfamily_PTPRB_pd | Subfamily PTPRB | 1222-1507 | 4.3e-109 | 359.1 | In-house | 3-292 (293) | alignment | ||
Range on Protein: 1222-1507
Range on HMM: 3-292/293.0
QRQSISVSMFPDYVKRLHANTDHLFSEEYELITIKSPSLPHEASQQTCNIEKNRYGNINSFDETRVVLTKIPGIEGSDYINANYIDGYGSRDTYIACQGP
. . |....| ..||...|..|. |||||| . . ..|.....| .|||| || ..|..|| |... . .||||||||||.|| |. .||.|||
kskpiklekfeehvkkmkadsdlrfseeyeelkavgkdqavkaaelavnraknrytnilpydhsrvkLaalkdesgsDYinanyipgynsprefiatqGP
LAETSPDFWRMIWEQKTSCIVMLTNCVEKGRPKCHQYWPQT-GSTTFGELTVTIIDQQVLAYYTIRTFKINNkDDESFEVKQFHYTAWPDFGVPDHPNPI
| || |||||.||.|.| |||||..||||. ||..|||.. ....|...||.. ...| ..||..||.. ..|. .|.|.|.|.|||.|||......
lpetvddfWrmvwekkssiivmltqlvekgkvkCeeYWPadeepvlyGdikvtlvaeeeledwvirelkiek.ekeerkvrqyhftsWpdhgvPektktl
ISFIRRVNNST----HTGPLVVHCSAGVGRSGTFIAIQSMMLMMETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELIKVGNSEQ
..|.|.|.... ...|.||||||||||.|||||.. .. .|.| ||.| .| ..|..||..||||.||.|.|.....|.. ...|.
ldfvrtvreaiektaskrPivvhCsaGvGRtGtfialdrllqaieeedyvdifgivaelReeRnllvqtekqYifihqcvldllrkkeeek
|
|||||||||
0051299 | (Phosphotyrosine protein) phosphatases II | 1225-1500 | 3.6e-105 | 346.8 | In-house | 4-286 (288) | alignment | ||
Range on Protein: 1225-1500
Range on HMM: 4-286/288.0
SISVSMFPDYVKRLHANTDHLFSEEYELITIKSPSLPHEASQQTCNIEKNRYGNINSFDETRVVLTKIPGIEGSDYINANYIDGYGSRDTYIACQGPLAE
.|||. . ..|..|.|| ... ||.| .. . |.|. |.. .|.||||| .| .| .||.|. ..|.||||||||.||||| . ..||.|||| .
eisveellklvlkllangltglleefeellsllpdltlsaallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyidgynlkrkfIatqgPlpn
TSPDFWRMIWEQKTSCIVMLTNCVEKGRPKCHQYWPQTGSTTFGELTVTIIDQQVLAYYTIRTFKINN-----KDDESFEVKQFHYTAWPDFGVPDHPNP
| |||||.|||....|||||..||.|| ||.||||. ||.|.|..|||... .||..||.||... | .|.||..|..||||.|||.||||.|..
tvedFWrmvweqnvrvIvmltklvelgrekcaqYwplggsltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdspel
IISFIRRVNNS--THTGPLVVHCSAGVGRSGTFIAIQSMMLMMETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELI
...|.|.|... . || ||||||||||.|||||. .. ..|.||.|||...| .|..|..||||. ||.||.. |.|..
lldflrlvrkalasgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyealleyl
|
|||||||||
subfamily_PTPRG_pd | Subfamily PTPRG | 1226-1511 | 9.6e-105 | 345.9 | In-house | 1-298 (563) | alignment | ||
Range on Protein: 1226-1511
Range on HMM: 1-298/563.0
ISVSMFPDYVKRLHANTDHLFSEEYE--LITIKSPSLPHEASQQTCNIEKNRYGNINSFDETRVVLTKIPGIEGS-DYINANYIDGYGSRDTYIACQGPL
. |. | .| |||..|. ||||.| ...| .|. |.||...| .|||| || ..|..|| |...||.... ||||||||||| . .|| ||||
vpvkefakhvaslhadgdigfseefealqsetiskdldaehsqkpenkrKnRylnivaydrsRvklsplpgkkkklDYinAnyidGyqkskafiatqgpl
AETSPDFWRMIWEQKTSCIVMLTNCVEKGRPKCHQYWPQTGSTTFGELTVTIIDQQVLAYYTIRTFKINN------KD-DESFEVKQFHYTAWPDFGVPD
..| |||||||||... |||.|| ||.|| ||..|||. .| |.|.|.||.|...|||.||.||..|.| |. |. .|.|.||| ||| |||.
kdtfddFWrmiWeqnvaiivmitnlvergrrkcdvYWPkdesetygalqvtlieeevlalytvrtlviknlklkkkkqcdteklvrqyhytkWPdhgvPe
HPNPIISFIRRVNNSTHT--GPLVVHCSAGVGRSGTFIAIQSMMLMMETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELIKVGNSEQTVQN
|. | ..|... . .... ||.||||||||||.||.|...... ...| .|.||.|. .| .||..|||| ||.|.|| |.|.|. .. | . ..
hslpvLifvkkssaankaeaGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvqteEqYiflhdalleaiasketellaeq
|
|||||||||
0050432 | (Phosphotyrosine protein) phosphatases II | 1237-1502 | 5.3e-102 | 336.5 | In-house | 35-301 (308) | alignment | ||
Range on Protein: 1237-1502
Range on HMM: 35-301/308.0
RLHANTDHLFSEEYELITIKSPSLPHEASQQTCNIEKNRYGNINSFDETRVVLtkipGiEGSDYINANYIDGY--GSRDTYIACQGPLAETSPDFWRMIW
.|. .|..||.| .. . |.|. ..... .|..|||| .| .| .||.| . ||||||||.|.||| ... ..||.|||| .| |||||.|
lekaldlglleeefeellsvkplleysvallpenkdkNrykdilpydhsRVkl....d.egsdYInAsyvdgyssklprkfIatqgPlpntvedFwrmvw
EQKTSCIVMLTNCVEKGRPKCHQYWPQT---GSTTFGELTVTIIDQQVLAYYTIRTFKINN-KDDESFEVKQFHYTAWPDFGVPDHPNPIISFIRRVNNS
||....|||||..||.||.||.|||| . ||...| .|||.....||..||.||... | .|.||..|..||||.|||.|||..|.....|...|..|
eqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseevlddytvrtleltnlgdgesrtvthfhytnWpdhgvPpspeilldflelvrks
THTGPLVVHCSAGVGRSGTFIAIQSMMLMMETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELIKV
|| ||||||||||.|||||. .. ..|.||.||||. | .|..|..||||. ||.|... |.|..|
lpggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylflyralleylkl
|
|||||||||
subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 1223-1520 | 6.9e-102 | 335.8 | In-house | 2-303 (319) | alignment | ||
Range on Protein: 1223-1520
Range on HMM: 2-303/319.0
RQSISVSMFPDYVKRLHANTDHLFSEEYELITIKSPSlPHEASQQTCNIEKNRYGNINSFDETRVVLTKIPGIEGSDYINANYIDGYGSRDTYIACQGPL
.. | | . ...|.|......|. .|..|. . .. . ... | .|||| || ..| |||||....|.||||||||..|||| |. .|| |.||
dteievqeLkerlkalastgetllekefkllkeavnd.tfdsaskeenkkknryqnilaydrtrvvlseldgvegsdyinasfidgyqerekfiatqaPl
AETSPDFWRMIWEQKTSCIVMLTNCVEKGRPKCHQYWPQTGSTTFGELTVTIIDQQVLAYYTIRTFKINNKDDES--FEVKQFHYTAWPDFGVPDHPNPI
..| |||||.||...|..||||. |||.. |...|||.. ...|.|.||. ... |. | || .|.|.| .| |||.|.||.||| .||.. .
entiedfWrmvWeeessivvmltklveklkvklkkywpeenfeeyGrlivtleeeeeledyiirklklnkkssevetRevkhfqyteWpdhdvPekatsl
ISFIRRVNNSTHT---GPLVVHCSAGVGRSGTFIAIQSMMLMMETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELIKVGNSEQTVQNFPKEAK
. ...|...|.. ||.|||||||||| ||||... |. .. || .|||..| .| .|| |||...|| |... |.| ...|..| ||.. . |
ldllkrirksrektqsgPivvhCsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyealleaveagdteievqdlrdrlk
ILL
|
qla
|
|||||||||
0040438 | (Phosphotyrosine protein) phosphatases II | 1231-1522 | 8.6e-102 | 335.9 | In-house | 5-298 (317) | alignment | ||
Range on Protein: 1231-1522
Range on HMM: 5-298/317.0
FPDYVKRLHANTDHLFSEEYELITIKSPSlPHEASQQTCNIEKNRYGNINSFDETRVVLTKIPGIEGSDYINANYIDGYGSRDTYIACQGPLAETSPDFW
.......|... ....||.| . ... . . .. .|..|||| .| .| .||.|. ..|...||||||.|.||. ....||.|||| .| |||
lllalldllksdftalleefedllslkld.tysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPlpntvedFw
RMIWEQKTSCIVMLTNCVEKGRPKCHQYWPQTGSTTFGELTVTIIDQQVLAYYTIRTFKINN-KDDESFEVKQFHYTAWPDFGVPDHPNPIISFIRRVNN
||.|||....|||||...|.||.||.||||. ...|.|..|||... ..||..|.||... . .|.||..|..||||.|||.|||..|.....|...|..
rmvweqgvtvivmLteleelgrekcaqYwplgetltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavre
S--THTGPLVVHCSAGVGRSGTFIAIQSMMLMMETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELIKVGNSEQTVQNFPKEAKILLTT
. . ||..|||||||||.|||||. |. ..|.||.|||.. | .|..|...|||..||.|..| | |..| .. ....... . ||..
aledpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleylkrkltlepaselklkllkllip
|
|||||||||
0046845 | (Phosphotyrosine protein) phosphatases II | 1246-1502 | 2e-97 | 321.3 | In-house | 2-276 (284) | alignment | ||
Range on Protein: 1246-1502
Range on HMM: 2-276/284.0
FSEEYELITIKSPSL--PHEASQQTCNIEKNRYGNINSFDETRVVLTKIPG-IEGSDYINANYIDGY-----GSRDTYIACQGPLAETSPDFWRMIWEQK
. ||.| .. ..| . .... .|..|||| .| .| .||.|. ..| .|.||||||.|.||| .. ..||.|||| .| |||||.|||.
leeefeellsltvklllslsvallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqn
TSCIVMLTNCVEKGRPKCHQYWPQTG-STTFGELTVTIIDQQVLAYYTIRTFKINNK--DDESFEVKQFHYTAWPDFGVPDHPNPIISFIRRVNNS----
...|||||..||.|| ||.||||..| . |.|..|||... .| .||.||... |. ..||..|..||||.|||.|||..|.....|.| |...
vrvIVmltelvengrekcaqYwplegevltygdftvtllseevkddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrellenl
THTGPLVVHCSAGVGRSGTFIAIQSMMLMMETEG---KVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELIKV
|| ||||||||||.|||||. .. ..|.|| .|||.. | .| .|..||||..||.||.. |.|..|
pgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleylkl
|
|||||||||
0039614 | (Phosphotyrosine protein) phosphatases II | 1223-1502 | 8.3e-97 | 319.5 | In-house | 11-291 (297) | alignment | ||
Range on Protein: 1223-1502
Range on HMM: 11-291/297.0
RQSISVSMFPDYVKRLHANTDHLFSEEYELITIKSPSlpHEASQQTCNIEKNRYGNINSFDETRVVLTKIPGI-EGSDYINANYIDGYGS-RDTYIACQG
.|..|... ......|| .|. .|.| . |. . .. .|..|||| .| .| .||.|. ..| ..||||||.|.||| ...||.||
sipiplsvldlllllekansktllllefeellslkpd..ysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIatqg
PLAETSPDFWRMIWEQKTSCIVMLTNCVEKGRpKCHQYWPQTGStTFGELTVTIIDQQVLAYYTIRTFKINNkDDESFEVKQFHYTAWPDFGVPDHPNPI
|| || |||||.|||....|||||..||.|| ||.||||..|. |.|..||| .. ..|..||.||... | ..||..|..|.|| |||.|||.... .
PlpetvedFwrmvweqgvtvivmLtklvelgr.kcaqywpeegg.tygdftvtllkvehldgytvrtlevtn.ngesrtvthfqytgwpdhgvppslell
ISFIRRVNNST----HTGPLVVHCSAGVGRSGTFIAIQSMMLMMETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELIKV
..|.. |.. || .|||||||||.|||||. |. ..|.||.|||.. | .| .|...|||. ||.|..| |.||.|
leflelvrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydallellkr
|
|||||||||
0036941 | (Phosphotyrosine protein) phosphatases II | 1236-1507 | 9e-97 | 319.2 | In-house | 5-284 (297) | alignment | ||
Range on Protein: 1236-1507
Range on HMM: 5-284/297.0
KRLHANTDHLFSEEYELITIKSPSLPHEASQQTCNIEKNRYGNINSFDETRVVLtkiPGiEGSDYINANYIDGYGSRDTYIACQGPLAETSPDFWRMIWE
. ... .|...|.| .. .. . .... .|.||||| .| .| |||.| .. ||||||||.|.|||. ..||.|||| .| |||||.||
llekllflalllkefeellpllllgslsvallpenleknRykdilpydhtRVkl...dd.egsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvwe
QKTSCIVMLTNCVEKGRPKCHQYWPQT--GSTTFGELTVTIIDQQV--LAYYTIRTFKINN-KDDESFEVKQFHYTAWPDFGVPDHPNPIISFIRRVNNS
|....|||||..||.||.||.|||| . .| |.|..||| .. .| |..||.||... . ...||..|..|||| |||.|||..|.....||..|..
qnvtvIvmltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrkv
T----HTGPLVVHCSAGVGRSGTFIAIQSMMLMME---TEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELIKVGNSEQ
|| .|||||||||||||||. |. ..| .||.||....|. .|..|. .|||. ||.|... | ||.| ..
lkllpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallellkkkltke
|
|||||||||
subfamily_PTPRA_pd | Subfamily PTPRA | 1224-1517 | 6.6e-96 | 316.0 | In-house | 12-312 (330) | alignment | ||
Range on Protein: 1224-1517
Range on HMM: 12-312/330.0
QSISVSMFPDYVKRLHANTDHLFSEEYELITIKSPSLPHEASQQTCNIEKNRYGNINSFDETRVVLTKIPGIEGSDYINANYIDGYGSRDTYIACQGPLA
. | . . ... |. .|| ||.. . . |.... | ||||. || .| .||.|... |.| |||||| .|||| .|..||.|||..
fplpvekleeeirirsaddnklfreefnalPagpiqatlelaskeenkeknrvvnilPydfsrvilsvkeGveesdyinasfidGykekdkfiaaqGPke
ETSPDFWRMIWEQKTSCIVMLTNCVEKGRPKCHQYWPQTGSTTFGELTVTIIDQQVLAYYTIRTFKINNKDD-----ESFEVKQFHYTAWPDFGVPDHPN
|| ||||||||||.. |||||. |. . ||.||||. |. |.|...|.. |..|| ||.| | .... | .| |.|||.|.|||.||| .|
etvedfwrmiweqksativmltelkerkeekcaqywPdeGlvtyGnirvevedetvlvdytvrkflvqqlpdatrekksrlvrqfhftswPdvGvPfepi
PIISFIRRVN--NSTHTGPLVVHCSAGVGRSGTFIAIQSMMLMMETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELIKVGNSEQTVQNFPKEA
.......|. | ..||.||||||||||.||||...... ....|.|||||.|| .| .| ||||. || |.. | | |..| | . |
GmlkllkkvkklnqqsagpivvhcsaGvGrtGtfivldavlervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvlleyylygdteldvsslekhl
K
.
q
|
|||||||||
0047943 | (Phosphotyrosine protein) phosphatases II | 1239-1500 | 8.9e-96 | 315.8 | In-house | 7-272 (273) | alignment | ||
Range on Protein: 1239-1500
Range on HMM: 7-272/273.0
HANTDHLFSEEYELITIKSPSLPHEASQQTCNIEKNRYGNINSFDETRVVLtkipGIEGSDYINANYIDGYGSRDTYIACQGPLAETSPDFWRMIWEQKT
... .|. ||.||.. |.|. .... .|..|||| .| .| .||.| | .|||||||.|.||| . ..||.|||| .| |||||.|||..
kllgltllleefelllslkplltysvallpenkdknrykdilpydhsrvkl....gdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvweqnv
SCIVMLTNCVEKGRPKCHQYWPQTG---STTFGELTVTIIDQQVLAYYTIRTFKINN-KDDESFEVKQFHYTAWPDFGVPDHPNPIISFIRRVNN----S
..|||||..||.||.||.||||..| |.|.|..|||...... ..||.||... | ...||..|..|||| |||.|||........||. |.. .
rviVmLtelvelgrekcaqYwpleggelsltygkftvtllseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvrkaleal
THTGPLVVHCSAGVGRSGTFIAIQSMMLMMETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELI
. || ||||||||||.|||||. .. ..|.||.|||.. | .| .| .||||. ||.|... |.|..
psngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyealleyl
|
|||||||||
0043336 | (Phosphotyrosine protein) phosphatases II | 1226-1500 | 1e-94 | 312.4 | In-house | 2-277 (278) | alignment | ||
Range on Protein: 1226-1500
Range on HMM: 2-277/278.0
ISVSMFPDYVKRLHANTDHLFSEEYELITIKSPsLPHEASQQTCNIEKNRYGNINSFDETRVVLTKIPGIEGSDYINANYIDGYGSRDTYIACQGPLAET
|||. .......|..| .|...|.| .. . . . .. .|..|||| .| .| .||.|. ..| ..||||||.|.||| ...||.|||| ||
isvkdllkallelllnlktllllefeellsfkl.dtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpet
SPDFWRMIWEQKTSCIVMLTNCVEKGRPKCHQYWPqTGSTTFGELTVTIIDQQVLAYYTIRTFKINN-KDDESFEVKQFHYTAWPDFGVPDHPNPIISFI
|||||.||.....|||||..||.||.||.|||| ||.|.|..||| .....|..||.||... | .|.||..| ..||..|||.|||........|.
vedFwrmvwelgvttivmLtelvelgrvkcaqYwp.ggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldfl
RRVNNS--THTGPLVVHCSAGVGRSGTFIAIQSMMLMMETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELI
..|.. . ||..|||||||||.|||||. .. ..|.||.||... | ..|..| .|||. ||.|... | |..
kavrealedsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyealleyl
|
|||||||||
subfamily_Ptp69D_pd | Subfamily Ptp69D | 1226-1516 | 1.2e-93 | 308.6 | In-house | 4-302 (307) | alignment | ||
Range on Protein: 1226-1516
Range on HMM: 4-302/307.0
ISVSMFPDYVKRLHANTDHLFSEEYELITIKSPSLPHEASQQTCNIEKNRYGNINSFDETRVVLTKIPGIEGSDYINANYIDGYGSRDTYIACQGPLAET
|.. .. .| . .||... .||| . . .. ..|.. | |||| .| .||.|||.|.||.| | ||||||..| || . ..|| |.|. .|
iaiddleealksrkrdtdfglakeyekLeareidkstkvsekkenalknRyedikafDktRvkLkkingkedsdYinasfikgykekkkfiaaqdPveat
SPDFWRMIWEQKTSCIVMLTNCVEKGRPKCHQYWPQTGSTTFGELTVTIIDQQVLAYYTIRTFKINNKD------DESFEVKQFHYTAWPDFGVPDHPNP
||||||.||. ||||.| || | ||..|||. . .|.. |...... .|.||.... .|. ..| .| |.|||.|.|. ||....
igDfWRmiaeqevtlivmlsnlteknrkkcakYWpiedevqygdilvklvseekhsdyiiReldvskkkeesgevedsrkvvqyhytgWkDskvPevarg
IISFIRRVNN--STHTGPLVVHCSAGVGRSGTFIAIQSMMLMMETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELIKVGNSEQTVQNFPKEA
.. .|..|.. ... .|.||||||||||||.|.|..|.. ...| |||.|..| |.|..|| .|| .||.|.. .|.. .. |.....|... ..
llklieqvrelyklnrsPivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnllvqsleqYvflyralldyssygdtdedvddledai
|
|||||||||
0045450 | (Phosphotyrosine protein) phosphatases II | 1222-1500 | 1.9e-93 | 308.8 | In-house | 5-304 (307) | alignment | ||
Range on Protein: 1222-1500
Range on HMM: 5-304/307.0
QRQSISVSMFPDYVKRLHANTDHLFSEEYELITIKSP--SLPHEASQQTCNIEKNRYGNINSFDETRVVLTKIPGI-EGSDYINANYI--------DGYG
. |.. .. .|..|... ... .|.| . . . ...... .|..|||| .| .| |||.|. ..| |.||||||.|. |||
lslfidalkllllvllllldfltgllkefekllsvtvfllgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgyd
SRDTYIACQGPLAETSPDFWRMIWEQKTSCIVMLTNCVEKGRPKCHQYWPQTGST-TFGELTVTIIDQQVLAYYTIRTFKINN--KDDESFEVKQFHYTA
. ...||.|||| || |||||.|||....|||||..||.||.||.||||..|.. |.|..||| .. ..|..||.||... . ...||..|..||||.
lkrkfIatqgPlpetvedFwrmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytg
WPDFGVPDHPNPIISFIRRVNN----STHTGPLVVHCSAGVGRSGTFIAIQSMMLMMETEGK---VDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELI
|||.|||........||..|.. .. || .|||||||||.|||||. |. ..|.||. ||... | .| .| .||.. ||.|... | ||.
wpdhgvppsfeelldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeallell
|
|||||||||
subfamily_PTPRD_pd | Subfamily PTPRD | 1548-1808 | 4.3e-93 | 307.9 | In-house | 29-287 (564) | alignment | ||
Range on Protein: 1548-1808
Range on HMM: 29-287/564.0
LNSIDVAIPSQYISASLPVNRAKNRYPDILPYESYRVRLLMLPGVSGSDYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCGLVED
..|. .. .|. |.|.||||| .|..|.. ||.| ...|..||||||||..||| . ...| |||||..|..|||||.||...| |||| |.|
ykkieegqqftweaankpaNkaKNRyanivaYdhsRVvLskvegdegsDYINAsfidgyrkrkayIAtqgPlaetiedFWRmvweqnsstiVmltkleEk
GKDQSVQYWPKDQLTQYGDMFIETISETDTGFYVIREITItHTKQGNEVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAHhLFGGGPVVVHDSSSVG
||.. .|||... ..||.. .. .|.. |.||.... ..|. .|.|...|||.|.| .. | .. .|.|.| |.... . ||.||| |. ||
gkvkchkYWPekgtetygeltVtleeeeeladyeirtfkl.kkkkssesreVrqFhFtsWPdhgvpesatslLdlirkvraln.epdagPivVhCSaGVG
RSGTFCIINIVIERLKVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYLESFDKY
|.|||..|....||.| |...||. ...|||.. . .| . .|. |....|.|.|.....
RTGtfividamlerikeektvDiyqyvkalrkqRnamVqteeQYiFiheailealacgnte
|
|||||||||
subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 1233-1501 | 1.1e-92 | 305.2 | In-house | 10-280 (288) | alignment | ||
Range on Protein: 1233-1501
Range on HMM: 10-280/288.0
DYVKRLHANTDHLFSEEYELITIKSPSLPHEASQQTCNIEKNRYGNINSFDETRVVLTKIPGIEGSDYINANYIDGYGSRDTYIACQGPLAETSPDFWRM
..|.. .|.. |||||. .. . ..|.... | .|||| || ..||.|| |.| . .|.|||||.||||.... .||| |||||.| |||..
akvakksarnrtgfseeynsLaalektksvtagrlavnakknRyrnilpyDekrvklkkleeeagaDYinasyidgekkkkkyiatqgPladtvndfWel
IWEQKTSCIVMLTNCVEKGRPKCHQYWPQTGS-TTFGELTVTIIDQQVLAYYTIRTFKINnKDDESFEVKQFHYTAWPDFGVPDHPNPIISFIRRVNN--
..|.||| |||||. ||.|. ||..|||... . .|..|||..... | .. |.. .. |. . .|..|..|.|||| |||. .|.. ..| |..
vyenktstivmltelveggktkCeeYWPdadkpknyGsvtvtlveskeledfvlrkllle.kkkteleitqyqylaWpdhgvPeskapllellrqvkvan
STHTGPLVVHCSAGVGRSGTFIAIQSMMLMMETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELIK
. |||..|||||||||.|||||.. .. ..|.| ..||...| .|..|. .|||. ||.|... |..||.
qadtgpiivhCsaGvGrtgtFialdalidaveeedyiDvagtvaklRkqRallvqtlkqYefiyevllslie
|
|||||||||
DSPc_SM00195 | 1246-1501 | 3.4e-91 | 300.6 | In-house | 2-263 (263) | alignment | |||
Range on Protein: 1246-1501
Range on HMM: 2-263/263.0
FSEEYELITIKSPSLPHEASQQTCNIEKNRYGNINSFDETRVVLTKIPGIEGSDYINANYIDGYGSRDTYIACQGPLAETSPDFWRMIWEQKTSCIVMLT
..||.| . . .. . . ... | .|||| || .|.||| |.|... |||||||||||.|. .. .|||.|||| .| |||||.||.|...|||||
lkeefekleestspketteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlt
NCVEKGRPKCHQYWPQT--GSTTFGELTVTIIDQQVLA-YYTIRTFKINNKDD-ESFEVKQFHYTAWPDFGVPDHPNPIISFIRRVNNSTH--TGPLVVH
...|.|. ||..|||.. |..|||...|...... ...||........ |...|.|..|..||| ||||.........| |..|. .||.|||
eeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivVh
CSAGVGRSGTFIAIQSMMLMMETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELIK
|||||||.|||..|.... .|.| |||.|. | .|..| ||||..||.|... ..|.||
CsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyik
|
|||||||||
PTPc_SM00194 | 1246-1501 | 3.4e-91 | 300.6 | In-house | 2-263 (263) | alignment | |||
Range on Protein: 1246-1501
Range on HMM: 2-263/263.0
FSEEYELITIKSPSLPHEASQQTCNIEKNRYGNINSFDETRVVLTKIPGIEGSDYINANYIDGYGSRDTYIACQGPLAETSPDFWRMIWEQKTSCIVMLT
..||.| . . .. . . ... | .|||| || .|.||| |.|... |||||||||||.|. .. .|||.|||| .| |||||.||.|...|||||
lkeefekleestspketteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlt
NCVEKGRPKCHQYWPQT--GSTTFGELTVTIIDQQVLA-YYTIRTFKINNKDD-ESFEVKQFHYTAWPDFGVPDHPNPIISFIRRVNNSTH--TGPLVVH
...|.|. ||..|||.. |..|||...|...... ...||........ |...|.|..|..||| ||||.........| |..|. .||.|||
eeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivVh
CSAGVGRSGTFIAIQSMMLMMETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELIK
|||||||.|||..|.... .|.| |||.|. | .|..| ||||..||.|... ..|.||
CsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyik
|
|||||||||
subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 1543-1810 | 2.8e-90 | 297.6 | In-house | 24-288 (318) | alignment | ||
Range on Protein: 1543-1810
Range on HMM: 24-288/318.0
KQFEKLNSIDvAIPSQYISaSLPVNRAKNRYPDILPYESYRVRLLMLPGVSGSDYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLC
...|.|. . . .... | |||.||||| .||.|.. ||.| || |. |||||||.|.||| | ...| .|.||..|..|||||.|| . ||||
eeyerlsrse.etvtslks.lepvnkaknryanilaydhtrvkLqmlegeegsDyinanyidGyrrkkayiaaqaPlpetieDfWrmvWeqnsavivmlt
GLVEDGKDQSVQYWPKDQLTQYGDMFIETISETDTGFYVIREITITHTKQgNEVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAHHLFGGGPVVVHD
..| ||.. .|||... ..||.. .| .|.... ||.||...|.|.. .|.|...|.|||.|... .| .. |.|.. |.||.. | ||.|||
qeeergkakvhryWPskgsrsygklvvelkeevelsdyvlrefkvtrtee.eesrqvrqyhytsWpdegvpesgaslldlvrqvskaqqksgagpivvhC
SSSVGRSGTFCIINIVIERLKVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYLESFDKYAN
|. ||| |.|....|..||.| |...|.| |.. ||.. . .| ||..|.|....|.|.|.|....
saGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqtedqyefiydvllealasgdtevd
|
|||||||||
subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 1225-1512 | 3.4e-90 | 297.3 | In-house | 3-295 (305) | alignment | ||
Range on Protein: 1225-1512
Range on HMM: 3-295/305.0
SISVSMFPDYVKRLHANTDHLFSEEYELITIKspSLPHEASQQTCNIEKNRYGNINSFDETRVVLTKIPGIEGSDYINANYIDGYGSRDTYIACQGPLAE
|... . |.| ....|. . ..|.... . . . . ... | .|||. .|. .|. |. ||. . . ||||||.|.||| ....||. |||| .
iialddlaayikearvysdkgleaqykslyee..eesidvgkkeankaknrlkeitlldddriiltekeslddsdyinasyvdgykrkkkyivaqgPlkn
TSPDFWRMIWEQKTSCIVMLTNCVEKGRPKCHQYWPQTGST--TFGELTVTIIDQQVLAYYTIRTFKINN--KDDESFEVKQFHYTAWPDFGVPDHPNPI
| ||||.|.| |.| |||||. || |. ||.||||.. . |||..|.. ... . |..| .|| . .|.|| | |.. | ||| |||. . .
tvadfWrliveekvstivmltklveggkdkCrqYWpesktekkefgefsvelksektasdyieRklkisiededkesrtvlqyqltdWPdhGvpqfatsl
ISFIRRVNNSTHTG---PLVVHCSAGVGRSGTFIAIQSMMLMMETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELIKVGNSEQTVQNF
.|.|.||... . . ||.|||||||||.|.|||.. .. ...|. ||||. . .|.|| .|||| .||.|.|| | |||. |. . ..|.
lslikrvqkdqkkdkgvpllVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkmvqtldqYvflhdaldelitcgdtsiigsnl
|
|||||||||
0051299 | (Phosphotyrosine protein) phosphatases II | 1540-1802 | 1.6e-89 | 295.4 | In-house | 24-286 (288) | alignment | ||
Range on Protein: 1540-1802
Range on HMM: 24-286/288.0
PLPKQFEKLNSIDVAipSQYISASLPVNRAKNRYPDILPYESYRVRLLMLPGVSGSDYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIV
| ..||.| |. . .. .|.|| |. ||||.|||||.. ||.| .|.||.|||||||||.||| . ..||.|||||.|||.|||||.||..|. ||
glleefeellsllpd..ltlsaallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyidgynlkrkfIatqgPlpntvedFWrmvweqnvrvIv
MLCGLVEDGKDQSVQYWPKDQLTQYGDMFIETISETDTGFYVIREITITHTK---QGNEVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAHHlFGGG
||..|||.|. .. |||| .. ..|||......||. . |..|....|... ...|.|....||||.| .. .|... .|.|.. ||.||. |||
mltklvelgrekcaqYwplggsltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdspellldflrlvrkala.sggg
PVVVHDSSSVGRSGTFCIINIVIERLKVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYL
||||| | |||.|||... ...|.|. ||..|.. ... ||.. ||.| . .|..|.|....|||
pvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyealleyl
|
|||||||||
subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 1232-1506 | 2.3e-89 | 294.6 | In-house | 15-296 (298) | alignment | ||
Range on Protein: 1232-1506
Range on HMM: 15-296/298.0
PDYVKRLHANTDHLFSEEYELITIKSPS---LPHEASQQTCNIEKNRYGNINSFDETRVVLTKIPGIEGSDYINANYIDGYGSRDTYIACQGPLAETSPD
. ... .... ...|.. .. | . .|..... | .|||| .| ..| .||||.|. . | |||||| ....| |...||.|.|| || |
qklaavkkkkkltgyalefqrlnsvsseieeeekevarkpenkkkNRyadiialdssRvvLekedadeesdYiNAsflhaykgrnafiatqaPltetved
FWRMIWEQKTSCIVMLTNCVEKGRPKCHQYWPQTGSTTFGELTVTIIDQQVLAYYTIRTFKINNKD-DESFEVKQFHYTAWPDFGVPDHPNPIISFIRRV
||||..|.. ..|||||| .|... |.|.|||..|..|.||.||.. ... | ...|..|...|. ... ||.|.|.| ||| ||| . . .. ..|.|
FWrmvteedigtiVmltnleeldktkyhkywPdegketygeitvsllskeefadlivrklkvskkkeekerevrqlhftsWpdkgvpenatsvldllrkv
NNST-HTG--PLVVHCSAGVGRSGTFIAIQSMMLMMETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELIKVGNSE
. |. ..| |..|.||||||||||||||.|.. ...| .||||. | .|.|| .||||.||.|... | .. .| |
rasqqqagnkpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavlealdsfnde
|
|||||||||
0040439 | (Phosphotyrosine protein) phosphatases II | 1263-1500 | 2.6e-88 | 291.1 | In-house | 4-246 (249) | alignment | ||
Range on Protein: 1263-1500
Range on HMM: 4-246/249.0
EASQQTCNIEKNRYGNINSFDETRVVLTKIPGIEGSDYINANYIDGYGSRDTYIACQGPLAETSPDFWRMIWEQKTSCIVMLTNCVEKGRPKCHQYWPQT
. .. .|..|||| .| .| .||.|. .|| ..||||||.||||| . ...||.|||| || .|||||.||.. ..|||||..||.|| ||.||||.
svallpenkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywplg
GSTTFGELTVTIIDQQVLAYYTIRTFKINN-KDDESFEVKQFHYTAWPDFGVPDHPNPIISFIRRVNNST----HTGPLVVHCSAGVGRSGTFIAIQSMM
||...|..||| .. .|...||.||... | .|.||..|....|| |||.|||........||..|.. ||..|||||||||.|||||. |.
gsleygdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylml
LMMETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELI
..|.|..||... | ..|..|...||.. ||.|... | ||.
eqlekelgvdleeavkllrsqRpgavqnpeqyrflyeallell
|
|||||||||
0050432 | (Phosphotyrosine protein) phosphatases II | 1540-1810 | 3.7e-88 | 291.1 | In-house | 43-307 (308) | alignment | ||
Range on Protein: 1540-1810
Range on HMM: 43-307/308.0
PLPKQFEKLNSIDVaiPSQYISASLPVNRAKNRYPDILPYESYRVRLlmlpGvSGSDYINASYVDGY--LRCNQFIMTQGPLSNTVDDFWRMIWEHRVSA
| ..||.|.|. . . .| .|.|| |. ||||.|||||.. ||.| . .||||||||||||| . ..||.|||||.|||.|||||.||..|.
lleeefeellsvkp..lleysvallpenkdkNrykdilpydhsRVkl....d.egsdYInAsyvdgyssklprkfIatqgPlpntvedFwrmvweqnvrv
IVMLCGLVEDGKDQSVQYWPKD---QLTQYGDMFIETISETDTGFYVIREITITHTKQGnEVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAHhlfG
||||. |||.|. . |||| . . ..||.......||. . |..|....|... | |.| ...||||.| . ..|| . .|.|.. ||.| . .
IvmLtklvengrekcaqYwplelgggsleygkftvtllseevlddytvrtleltnlgdg.esrtvthfhytnWpdhgvPpspeilldflelvrksl...p
GGPVVVHDSSSVGRSGTFCIINIVIERLKVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYLESFDKYAN
|||.||| | |||.|||... ...|.|. ||..|.| ... ||.. || | ...|..|.|....|||... ...|
ggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylflyralleylklkltkln
|
|||||||||
subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 1235-1501 | 1e-86 | 285.6 | In-house | 6-277 (281) | alignment | ||
Range on Protein: 1235-1501
Range on HMM: 6-277/281.0
VKRLHANTDHLFSEEYELITIKSPSLPHEASQQTCNIEKNRYGNINSFDETRVVLTKIPGIEGSDYINANYIDGYGSRDTYIACQGPLAETSPDFWRMIW
.|.|..| .. | |||| .. . . .||.. |..|||| || ..| |||..|. . .||||||...|| . |||.|||. .. .||.|.|
lkqlsqndnaGfieeyeklaaigvdntataskadenvlknrYsnivaYDatrvkvtpneenkntDYinanfvpgykgekeyiatqgPvPaslvafWqmvw
EQKTSCIVMLTNCVEKGRPKCHQYWPQTG-STTFGELTVTIIDQQVLAYYTIRTFKINNKDDESFEVKQFHYTAWPDFGVPDHPNPIISFIRRVN---NS
||| | |||.|. .|.|. |||.|||. ....|..||. . .. | | |.||..... |. ||.|..|||||| |||. .. ...| . |. ..
eqkvsaivmvtreieagklkChrYWPddnselkygdvtvkstaeeekatyierkfkleresgetreveqlaytaWPdhGvPattkellefrkevlkltek
THTGPLVVHCSAGVGRSGTFIAIQSMMLMMETE-GKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELIK
. |||.||||||||.||.||. .. .|.| ..|| . | ..|..||.|||| .|| ||. ... ..
ktkaplvihCsaGvGrtGtyialDrlvkaveaeleeldvkavvaelrkernlmvqtvvqyefvykavldald
|
|||||||||
0042113 | (Phosphotyrosine protein) phosphatases II | 1265-1500 | 1e-86 | 285.6 | In-house | 4-243 (245) | alignment | ||
Range on Protein: 1265-1500
Range on HMM: 4-243/245.0
SQQTCNIEKNRYGNINSFDETRVVLTKIPGIEGSDYINANYIDGYGSRDTYIACQGPLAETSPDFWRMIWEQKTSCIVMLTNCVEKGRPKCHQYWPQTGS
.. .|..|||| .| .| |||.|. ..| ..||||||.|.||| ...||.||||.|| .|||||.||.. ..|||||...|.||.||.||||. .|
allpenkdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywplges
TTFGELTVTIIDQQVLAYYTIRTFKINN-KDDESFEVKQFHYTAWPDFGVPDHPNPIISFIRRVNN---STHTGPLVVHCSAGVGRSGTFIAIQSMMLMM
.|.|..||| .. ..|..||.||... | .||||.|| ..||. |||.||||... ...|...|.. .. ||..|||||||||.|||||. |. ..
ltygdftvtllseehlddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleql
ETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELI
|.|..|.... | ..| .| .|||. ||.|... | ||.
ekelgvsleeavkelrsqRpgavqtpsqyrflyeallell
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 1270-1497 | 1.5e-86 | 285.0 | Pfam-A | 1-234 (235) | alignment | ||
Range on Protein: 1270-1497
Range on HMM: 1-234/235.0
NIEKNRYGNINSFDETRVVLtkiPGIEG-SDYINANYIDGYGSRDTYIACQGPLAETSPDFWRMIWEQKTSCIVMLTNCVEKGRPKCHQYWP--QTGSTT
| .|||| .| .|.||| | | || ||||||||..|| . ..||.|||| .| |||||.|..|...|||||...|||| ||.|||| . .|.|
nkkknRykdilpydktrvkl...kgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeeslt
FGELTVTII-DQQ-VLAYYTIRTFKINNKDDES--FEVKQFHYTAWPDFGVPDHPNPIISFIRRVNNST--HTGPLVVHCSAGVGRSGTFIAIQSMMLMM
.|...|.. ... . ||.|......|..|| .||||.|||.||| |||..|......||.|..|. ..||.||||||||||.|||.|.. .. ..
ygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleql
ETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLV
|.|..|||...| .|..|. |||...||.|... ..
eaeeevdvlqivkelRkqRpgmvqsleqYiflykail
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 1270-1497 | 1.5e-86 | 285.0 | In-house | 1-234 (235) | alignment | ||
Range on Protein: 1270-1497
Range on HMM: 1-234/235.0
NIEKNRYGNINSFDETRVVLtkiPGIEG-SDYINANYIDGYGSRDTYIACQGPLAETSPDFWRMIWEQKTSCIVMLTNCVEKGRPKCHQYWP--QTGSTT
| .|||| .| .|.||| | | || ||||||||..|| . ..||.|||| .| |||||.|..|...|||||...|||| ||.|||| . .|.|
nkkknRykdilpydktrvkl...kgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeeslt
FGELTVTII-DQQ-VLAYYTIRTFKINNKDDES--FEVKQFHYTAWPDFGVPDHPNPIISFIRRVNNST--HTGPLVVHCSAGVGRSGTFIAIQSMMLMM
.|...|.. ... . ||.|......|..|| .||||.|||.||| |||..|......||.|..|. ..||.||||||||||.|||.|.. .. ..
ygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleql
ETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLV
|.|..|||...| .|..|. |||...||.|... ..
eaeeevdvlqivkelRkqRpgmvqsleqYiflykail
|
|||||||||
0046845 | (Phosphotyrosine protein) phosphatases II | 1541-1810 | 1.6e-86 | 285.5 | In-house | 2-282 (284) | alignment | ||
Range on Protein: 1541-1810
Range on HMM: 2-282/284.0
LPKQFEKLNSIDVAIPSQYISASLPVNRAKNRYPDILPYESYRVRLLMLPGV-SGSDYINASYVDGY-----LRCNQFIMTQGPLSNTVDDFWRMIWEHR
| ..||.|.|. | . .. | || |. ||||.|||||.. ||.| .|.| ..|||||||||||| ....||.|||||.|||.|||||.||..
leeefeellsltvklllslsvallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqn
VSAIVMLCGLVEDGKDQSVQYWPKDQ-LTQYGDMFIETISETDTGFYVIREITITHTKQGNEVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAHHL-
|. ||||..|||.|. . |||| .. .|||......||. . |..|....|... ..|.| ...||||.| ....||.. |.... ||....
vrvIVmltelvengrekcaqYwplegevltygdftvtllseevkddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrellenl
FGGGPVVVHDSSSVGRSGTFCIINIVIERLKVEG---MIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYLESFDKYAN
||||.|||.| |||.|||... ...|.|. || ..|.. ... ||.. || | ...|..|.|....||| .. ....
pgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleylklkltlle
|
|||||||||
subfamily_PTPRK_pd | Subfamily PTPRK | 1235-1512 | 1.8e-86 | 284.8 | In-house | 13-289 (314) | alignment | ||
Range on Protein: 1235-1512
Range on HMM: 13-289/314.0
VKRLHANTDHLFSEEYELITIKspslpHEASQQTCNIEKNRYGNINSFDETRVVLTKIPGIEGSDYINANYIDGYGSRDTYIACQGPLAETSPDFWRMIW
.. |... . | |||| . .|... | ||||.|.| ..| .||.|. | | ||||||..||.| .|. |||| || ||||...
iallkraegygfkeeyeslfeg.....wdaakkdenreknrsgdilaydrsrvflitidgdpssdyinaalidsykrpaafivtqgPlqetvkdfWrlvy
EQKTSCIVMLTNCVEKGRPKCHQYWPQTGSTtFGELTVTIIDQQVLAYYTIRTFKINN---KDDESFEVKQFHYTAWPDFGVPDHPNPIISFIRRVNNST
......|||||. ||.|| || .|||. ... .|.. |.... ..|| . .|.|.... . .| ||.||....|||..|| . . .....|||..|.
dencasivmltelvevgrvkClkyWPedtev.ygdikvelvetellaelvvrifrveklargqeeirevrqfqflgWpdhdvPvsatgllklvrrvkksq
--HTGPLVVHCSAGVGRSGTFIAIQSMMLMMETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELIKVGNSEQTVQNF
. |..||||||| ||.||||||.... |.|.|| ||||| | ..| .. ||.|| ||.|..| ..| .|.. | .|
eeeaGrivvhCsaGaGrtGtfiaidivldmieregvvdvfnavktlrsrkvnmveteeqykfiydvileaclcgetaipvsef
|
|||||||||
subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 1548-1806 | 3.5e-86 | 284.2 | In-house | 29-287 (319) | alignment | ||
Range on Protein: 1548-1806
Range on HMM: 29-287/319.0
LNSIDVAIPSQYISASLPVNRAKNRYPDILPYESYRVRLLMLPGVSGSDYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCGLVED
. .. | . .. ||| . |. ||||..||.|. || | |.|| ||||||||..||| . ..|| ||.||.||..|||||.||...| .|||..|||
fkllkeavndtfdsaskeenkkknryqnilaydrtrvvlseldgvegsdyinasfidgyqerekfiatqaPlentiedfWrmvWeeessivvmltklvek
GKDQSVQYWPKDQLTQYGDMFIETISETDTGFYVIREITITHTKQGNEVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAHHLFGGGPVVVHDSSSVG
.| . .|||. . ..|| . .. .| . |.||.... . .. | |..|.|.||.|.... | .. .|.|.. ..|... ||.||| | ||
lkvklkkywpeenfeeyGrlivtleeeeeledyiirklklnkkssevetRevkhfqyteWpdhdvPekatslldllkrirksrektqsgPivvhCsaGvG
RSGTFCIINIVIERLKVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYLESFD
| |||.......||.| ||..|.| |. || . . .| . .|.||.|....|..|..|
RtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyealleaveagd
|
|||||||||
0045098 | (Phosphotyrosine protein) phosphatases II | 1245-1502 | 3.8e-85 | 280.9 | In-house | 8-274 (278) | alignment | ||
Range on Protein: 1245-1502
Range on HMM: 8-274/278.0
LFSEEYELITIKSPSLPHEASQQTCNIEKNRYGNINSFDETRVVltkipgiegsDYINANYIDGYgsRDTYIACQGPLAETSPDFWRMIWEQKTSCIVML
.. |.| . . .. . .. .|..|||| .| .| .||. |||||.||||| ....||.|||| .| |||||.||.....||||
dlllefefllllgipseitpalylgnldknRykdilpydhsrVk..........dYINAsyidgy..pkkfIatqgPlpstvadfwrmlwelgitvivml
TNCVEKGRPKCHQYWPQTGSTTFGELTVTIIDQQVLAYYTIRTFKINN-----KDDESFEVKQFHYTAWPDFGVPDHP--NPIISFIRRVNNST------
|..||.|| ||.|||| || |.|..|||... .|| .||.||... | .|.||..|...||. |||.|||..| ............
telvelgrekcaqywpeggsltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllasl
---------HTGPLVVHCSAGVGRSGTFIAIQSMMLMMetEGKVDVFNFVLDMRHKRNY-MVQTEAQYMFVHDSLVELIKV
. || .|||||||||.||..|. |. .. ||.||... | .| .|.. .||.. ||.|... |.||..
llsslllldsggpvlVHCsaGvgRtGtlvaaylmlell..eggvdlleavkelrsqRpglavqnleqyrflyefllelllr
|
|||||||||
0047943 | (Phosphotyrosine protein) phosphatases II | 1541-1802 | 3.5e-84 | 277.8 | In-house | 14-272 (273) | alignment | ||
Range on Protein: 1541-1802
Range on HMM: 14-272/273.0
LPKQFEKLNSIDVaiPSQYISASLPVNRAKNRYPDILPYESYRVRLlmlpGVSGSDYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVM
| ..||.| |. . . | |.|| |. ||||.|||||.. ||.| | .||||||||||||| . ..||.|||||.|||.|||||.||..|. |||
lleefelllslkp..lltysvallpenkdknrykdilpydhsrvkl....gdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvweqnvrviVm
LCGLVEDGKDQSVQYWPKDQ---LTQYGDMFIETISETDTGFYVIREITITHTKQGNeVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAHHLF-GGG
|. |||.|. . |||| .. ..||.......||. . |..|....|... |. .| ...||||.| ....||.. |...| ||.||.. . ..|
LtelvelgrekcaqYwpleggelsltygkftvtllseetkddytvrtleltnlgtge.srtvthfhytgwpdhgvppslesllefielvrkalealpsng
PVVVHDSSSVGRSGTFCIINIVIERLKVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYL
||||| | |||.|||... .....|. ||..|.. ... ||.. ||.| ...|..|.|....|||
pvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyealleyl
|
|||||||||
0040438 | (Phosphotyrosine protein) phosphatases II | 1544-1805 | 8.1e-84 | 276.9 | In-house | 23-279 (317) | alignment | ||
Range on Protein: 1544-1805
Range on HMM: 23-279/317.0
QFEKLNSIDVAipsQYISASLPVNRAKNRYPDILPYESYRVRLLMLPGVSGSDYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCG
.||.| |... | |.||.|. ||||||||||.. ||.| |.|. .|||||||||||. ....||.|||||.|||.|||||.||..|. ||||.
efedllslkld...tysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPlpntvedFwrmvweqgvtvivmLte
LVEDGKDQSVQYWPKDQLTQYGDMFIETISETDTGFYVIREITITHTkQGNEVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAHHlFGGGPVVVHDS
|.|.|. .. |||| .. ..|||......||. . ...|....... ...|.| ...||||.| . ..||.. | |.. .|..| .||||.|| |
leelgrekcaqYwplgetltygdftvtllseeelagitlrtlevedl.gdsesrtvthfhytgWpdhgvppspdllldfleavreale.dpggpvlVHCs
SSVGRSGTFCIINIVIERLKVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYLESF
|||.|||... ...|.|. || .|.. ... ||.. ||.| ...|..|.|. . ||| .
aGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleylkrk
|
|||||||||
0036941 | (Phosphotyrosine protein) phosphatases II | 1540-1805 | 1.9e-83 | 275.5 | In-house | 14-280 (297) | alignment | ||
Range on Protein: 1540-1805
Range on HMM: 14-280/297.0
PLPKQFEKLnsIDVAIPSQYISASLPVNRAKNRYPDILPYESYRVRLlmlpGVSGSDYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIV
| |.||.| .. .. . |.|| |. ||||.|||||.. ||.| . .||||||||||||| ....||.|||||.|||.|||||.||..|. ||
lllkefeel..lpllllgslsvallpenleknRykdilpydhtRVkl....ddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqnvtvIv
MLCGLVEDGKDQSVQYWPKD--QLTQYGDMFIETISETD--TGFYVIREITITHTkQGNEVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAHHLF-G
||. |||.|. . |||| . . .|||......|.. . |..|....|.| ...|.| ...||||.| ....|... |.|.| ||.|...|. .
mltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdt.gngesrtvthfhytgwpdhgvpespaslldfielvrkvlkllps
GGPVVVHDSSSVGRSGTFCIINIVIERLK---VEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYLESF
||||.|| | |||||||... .....|. || .||. ... ||.. ||.| ...|..|.|... |.| ..
ggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallellkkk
|
|||||||||
subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 1265-1516 | 3.2e-83 | 274.7 | In-house | 56-307 (319) | alignment | ||
Range on Protein: 1265-1516
Range on HMM: 56-307/319.0
SQQTCNIEKNRYGNINSFDETRVVLTKIPGIEGSDYINANYIDGYGSRDTYIACQGPLAETSPDFWRMIWEQKTSCIVMLTncvekgRPKCHQYWPQTGS
. | .|||..|| .||...| | .. |.|.|||||| ...|| ..| |||.|||| .| ||||||||...| ||.|| . || ||||. .
anldqnkdknriinilafdknvvklerliGeefsdyinasfvtGyqrkdkyiaaqGPldntladfWrmiweyncstivllt......kdkcsqywplkiv
TTFGELTVTIIDQQVLAYYTIRTFKINN--KDDESFEVKQFHYTAWPDFGVPDHPNPIISFIRRV----NNSTHTGPLVVHCSAGVGRSGTFIAIQSMML
. .. | . . | |..| ... . | . ...|||. ||| ||||.| ... ....| . | ..||||||||||.|..|... ..
ikeerfkvkvdsveetaeyvvrdielsedgkekdirkitqfhflGwpdvGvpdypsdlmrlvkkvrhltskenhranivvhcsaGvGrtGvyivldvlld
MMETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELIKVGNSEQTVQNFPKEA
.|. | .|||.||| |.| .|| .|| .||.|.. .|.| .|.|. .. .||
rmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleehlfghsdvampdfpayl
|
|||||||||
0039614 | (Phosphotyrosine protein) phosphatases II | 1543-1806 | 2.8e-82 | 271.8 | In-house | 36-293 (297) | alignment | ||
Range on Protein: 1543-1806
Range on HMM: 36-293/297.0
KQFEKLNSIDVaiPsqYISASLPVNRAKNRYPDILPYESYRVRLLMLPGV-SGSDYINASYVDGYLR-CNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVM
..||.| |. . . | | ||.|. ||||.|||||.. ||.| ...|| .|||||||||||| . ...||.|||||..||.|||||.||..|..|||
lefeellslkp..d..ysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIatqgPlpetvedFwrmvweqgvtvivm
LCGLVEDGKdQSVQYWPKDQLtQYGDMFIETISETDTGFYVIREITITHtkqGNEVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAHHLF-GGGPVV
|. |||.|. . .|||| .. .|||......... . |..|....|. ..|.| ...|.||.| ....||.. |.... ||..|. .||||.
Ltklvelgr.kcaqywpeegg.tygdftvtllkvehldgytvrtlevtn...ngesrtvthfqytgwpdhgvppslellleflelvrealaelpkggpvl
VHDSSSVGRSGTFCIINIVIERLKVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYLESFD
|| | |||.|||... ...|.|. || .|.. ... ||.. ||.| . .|..|.|. ..|.| ..
VHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydallellkrkl
|
|||||||||
subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 1269-1517 | 3.4e-82 | 271.1 | In-house | 24-272 (284) | alignment | ||
Range on Protein: 1269-1517
Range on HMM: 24-272/284.0
CNIEKNRYGNINSFDETRVVLTKIPGIEGSDYINANYIDGYGSRDTYIACQGPLAETSPDFWRMIWEQKTSCIVMLTncvekgRPKCHQYWPQTGSTTFG
| .|||.|.| .||...| | .. |.|.|||||| .| || ..| |||.|||| .| ||||||||...| ||.|| . || ||||. . . .
qnkdknrighilafdknvvklerliGeefsdyinasfitGyqrkdkyiatqGPldntladfWrmiweyncstivllt......kdkcsqywplkivikee
ELTVTIIDQQVLAYYTIRTFKINN--KDDESFEVKQFHYTAWPDFGVPDHPNPIISFIRRV----NNSTHTGPLVVHCSAGVGRSGTFIAIQSMMLMMET
. | . . . |..| ... . | . ...|||. ||| ||||.| ... ....| . | ..||||||||||.|..|... .. .|.
rfkvkvdsveeseeyvvrdielsedgkekdirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrtgvyivldvlldrmke
EGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELIKVGNSEQTVQNFPKEAK
| .|||.||| |.| .|| .|| .||.|.. .|.| .|.|. .. .|| .
ekqvdvynfvrdlrqqrntlvqdlvqykfiysalleehlfghsdvalpdfpayle
|
|||||||||
0045450 | (Phosphotyrosine protein) phosphatases II | 1535-1802 | 5.6e-82 | 271.2 | In-house | 23-304 (307) | alignment | ||
Range on Protein: 1535-1802
Range on HMM: 23-304/307.0
VTALSPLPKQFEKLNSIDVAIPSQYISASLPVNRAKNRYPDILPYESYRVRLLMLPGV-SGSDYINASYV--------DGYLRCNQFIMTQGPLSNTVDD
. |. | |.||||.|. | .. | .|.||.|. ||||.|||||.. ||.| |.| ..||||||||| ||| ....||.|||||..||.|
ldfltgllkefekllsvtvfllgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydlkrkfIatqgPlpetved
FWRMIWEHRVSAIVMLCGLVEDGKDQSVQYWPKD-QLTQYGDMFIETISETDTGFYVIREITITHTKQGNEVRNIKQFHYTDWSENKTPPTTGALMDMIV
||||.||..|..||||..|||.|. . .|||| . . .||.......||. . |..| ...|.... .|.| ...||||.| . ..||.. | |.|
FwrmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfeelldfie
LVQKAHHLF-GGGPVVVHDSSSVGRSGTFCIINIVIERLKVEGM---IDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYL
.|.||.. .||||.|| | |||.|||... .....|. ||. .|.. ... ||.. ||.| |..|..|.|. . |.|
evrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeallell
|
|||||||||
0037934 | (Phosphotyrosine protein) phosphatases II | 1265-1500 | 2.4e-81 | 268.1 | In-house | 5-242 (243) | alignment | ||
Range on Protein: 1265-1500
Range on HMM: 5-242/243.0
SQQTCNIEKNRYGNINSFDETRVVLtkipgiEGSDYINANYIDGYgsrDTYIACQGPLAETSPD----FWRMIWEQKTSCIVMLTNCVEKGRPKCHQYWP
.. .|..|||| .| .| .||.| |||||||||.|... ...||.|||| || | ||||.||.....|||||..||.|| ||.||||
allpenlsknrysdilpydhsrvkl......egsdyinanliyvt...prliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywp
qtGSTTFGELTVTIIDQQVLAYYTIRTFKINN--KDDESFEVKQFHYTAWPDFGVPDHPNPIISFIRRVN----------NSTHTGPLVVHCSAGVGRSG
|..|.|..|||......|..||.||... | ||....| ..||..|||.||||.|.....|.. |. . . ||..|||||||||.|
..gevtygdftvtllseehlddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtG
TFIAIQSMMLMMetegKVDVFNFVLDMRHKRNY-MVQTEAQYMFVHDSLVELI
|.||. |.|.. .||... | ..| .|.. .|||. ||.|... | ||.
tliaaylmllll....gvdleeavkllreqRpgkavqtpsqyrflyeallell
|
|||||||||
0043336 | (Phosphotyrosine protein) phosphatases II | 1542-1802 | 3.4e-81 | 268.1 | In-house | 23-277 (278) | alignment | ||
Range on Protein: 1542-1802
Range on HMM: 23-277/278.0
PKQFEKLNSIDVaipSQYISASLPVNRAKNRYPDILPYESYRVRLLMLPGVSGSDYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVML
..||.|.|... | | || |. ||||.|||||.. ||.| .|.|. .|||||||||||| ....||.|||||..||.|||||.||..|. ||||
llefeellsfkl...dtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpetvedFwrmvwelgvttivmL
CGLVEDGKDQSVQYWPkDQLTQYGDMFIETISETDTGFYVIREITITHTKQGNEvRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAHHlFGGGPVVVH
..|||.|. ...|||| .. ..|||.......|. . |..| ...|... |.. | . ..||..| ....|... |.|.. |..| . .|||.||
telvelgrvkcaqYwp.ggsltygdftvtllkeehlddytvrtlevtnlgdges.rtvthyhylgwpdhgvpeslsllldflkavreale.dsngpvlVH
DSSSVGRSGTFCIINIVIERLKVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYL
| |||.|||... ...|.|. || .|.. ... ||.. ||.| . .|..|.|. . |||
CsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyealleyl
|
|||||||||
subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 1224-1507 | 7.9e-81 | 266.4 | In-house | 4-286 (315) | alignment | ||
Range on Protein: 1224-1507
Range on HMM: 4-286/315.0
QSISVSMFPDYVKRLHANTDHLFSEEYELITIKsPSLPHEASQQTCNIEKNRYGNINSFDETRVVLTKIPGIEGSDYINANYIDGYGSRDTYIACQGPLA
| | . . || . .|.| | ..|| | | . .... | .|||| || ..|..|| | . ..|||.|||.|||| .. |||.|||..
qpipldqlityvaqkkastkngfkqdyesipgg.qlhpldvakkienkqknryiniiaydksrvqlpllendphsdyvnanfidGynkkrryiaaqgpnv
ETSPDFWRMIWEQKTSCIVMLTNCVEKGRPKCHQYWPQTgSTTFGELTVTIIDQQVLAYYTIRTFKINNKDdESFEVKQFHYTAWPDFGVPDHPNPIISF
.. ||||...|.. . |||||| ||. . |. .||| ..|..||| ....| ||.||. . .| . || |.|||.||| ||| . |.. .
asvkdfwrlvfeedigkivmltnlvegekrkaekywpdk.kviyGkitvtrkseevnteytvrtlsvvfgd.nirevvqlhytswpdmgvpkytiplmnl
IRRVN--NSTHTGPLVVHCSAGVGRSGTFIAIQSMMLMMETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELIKVGNSEQ
||.|. . . |..||||||||||.||||...... .|.| .||.||. .|..| |||. .|| |..| |.| . .|..
irtvkqhhtnsvgaivvhcsaGvGrtGtfitldavldqaeaenaidvynfitgvrqnrikmvqvaeqyqfiydalletfvcgdtsi
|
|||||||||
subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 1265-1501 | 1.2e-80 | 265.4 | In-house | 4-243 (250) | alignment | ||
Range on Protein: 1265-1501
Range on HMM: 4-243/250.0
SQQTCNIEKNRYGNINSFDETRVVLTKIPGIEGSDYINANYIDGYGSRDTYIACQGPLAETSPDFWRMIWEQKTSCIVMLTNCVEKGRPkCHQYWPQTGS
... | ||||| .| ..|..|||| | | . |||||| ...|| |...|| |||| .| |||||..|.|.. |||||| .|... .||||| ..
akkpqnkeknryadiialdssrvvLekekgdkesdyinasflhgyderkafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqywPveka
TTFGELTVTIIDQQVLAYYTIRTFKINNKD-DESFEVKQFHYTAWPDFGVPDHPNPIISFIRRVNNSTHT---GPLVVHCSAGVGRSGTFIAIQSMMLMM
...|..||.. .... | ||.|..|. .. .. |.|.|...||| |||.. . .. ....|. | .|..|.|||||||||.||||.... .
ekyGdvtvsllskeefadytkrklklskakkaderivrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidavlerl
ETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELIK
..| .||||... .|..| .|....||.||. . . ..
kkekvvdvfkvikvlrkdrphavesleqyvfvyeiilkald
|
|||||||||
subfamily_PTPN12_pd | Subfamily PTPN12 | 1260-1501 | 4.8e-80 | 263.5 | In-house | 30-278 (290) | alignment | ||
Range on Protein: 1260-1501
Range on HMM: 30-278/290.0
LPHEASQQTCNIEKNRYGNINSFDETRVVLTKIPGIEGSDYINANYIDGYGSRDTYIACQGPLAETSPDFWRMIWEQKTSCIVMLTNCVEKGRPKCHQYW
. ||.... |..|||| .| .|..||.|.|| . |||||||||.| | .. .||| ||||..| ||||||||.... .||. . || |. ||..||
ysteagekeenvkknrykDilPydksrvelskieeeegsdYinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCerYW
PQTGS--TTFGELTVTIIDQQVLA-YYTIRTFKINNKdDESFEVKQFHYTAWPDFGVPDHPNPIISFIRRVNNS--THTGPLVVHCSAGVGRSGTFIAIQ
|..| ..|||..|| .... . ..|||.|.... .|| .|.||||||||| ||| .......|. |.. .. |||||||||||| || |||.
peegeeelefgefevtleeekavdddflirtLkveaq.kesrkvyqfhYtaWPDhgvPssaksllelielvrelqesedaPlvvhCsaGvGrtGtiiaid
SMMLMMETE---GKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELIK
. ....| ..|||. ||..|..|. .|||. || .|. ...||..
yvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelvq
|
|||||||||
subfamily_PTPN9_pd | Subfamily PTPN9 | 1239-1500 | 5.8e-80 | 263.5 | In-house | 11-290 (297) | alignment | ||
Range on Protein: 1239-1500
Range on HMM: 11-290/297.0
HANTDHLFSEEYELITIKSPSLPHEASQQTCNIEKNRYGNINSFDETRVVLTKIPGIEGSDYINANYIDGYGSRDTYIACQGPLAETSPDFWRMIWEQKT
... . |.||. | .... .||.. .|.||||| .. .|||||||.|... | |||||||..||| ....|| |||| .|. |||||.|||..
kekgkrGlskeyaeirnepveGtflasklranleknrytdvlcydetrvvlakvdedeasdyinanfvdGykqkkafiatqGplkktvsdfWrmvWeqev
SCIVMLTNCVEKGRPKCHQYWP--QTGSTTFGELTVTIIDQQVLAYYTIRTFKIN-NKDDESFEVKQFHYTAWPDFGVPDHPNPIISFIRRVNNS-----
||| | .||.|| || |||| . |. ||.|.|. ..... |..|...|. |..|| .| | ...|||.|||. . .. ... | .
lvivmttrvvergrlkcgqyWpleeessaefgdlsvsnveveeeedykvrvleiknvkteesrkvthfqflsWPdyGvPssaaslldvlekvrekqalav
----------THTGPLVVHCSAGVGRSGTFIAIQSMMLMMETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELI
.. |.|||||||.||.||||.. . .|..|.|||.. | .| .| ...||. ||.| . ...|
kelgdewkghpsgPPivvhcsaGiGrtGtfitldiclsrleevgtvdvvetvkllrtqrafsiqtpeqyefcylavleya
|
|||||||||
subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 1535-1809 | 1.3e-79 | 262.5 | In-house | 23-297 (298) | alignment | ||
Range on Protein: 1535-1809
Range on HMM: 23-297/298.0
VTALSPLPKQFEKLNSIDVAIPSQ-YISASLPVNRAKNRYPDILPYESYRVRLLMLPGVSGSDYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEH
. |. . ..|..|||. |... . |. | |. ||||.||....| ||.| . |||||||....| . | ||.||.|| .|| |||||..|.
kkkltgyalefqrlnsvsseieeeekevarkpenkkkNRyadiialdssRvvLekedadeesdYiNAsflhaykgrnafiatqaPltetvedFWrmvtee
RVSAIVMLCGLVEDGKDQSVQYWPKDQLTQYGDMFIETISETDTGFYVIREITITHTKQGnEVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAHHLF
...|||| |.| .| . .|||... ..||.. .. |. . . ...|.......|. . |...|.|.| |... .| .. ...|.. |.. ..
digtiVmltnleeldktkyhkywPdegketygeitvsllskeefadlivrklkvskkkee.kerevrqlhftsWpdkgvpenatsvldllrkvrasqqqa
GGGPVVVHDSSSVGRSGTFCIINIVIERLKVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYLESFDKYA
| ||.|. |. |||||||..|. |.||.| | ..|.| ....||.| ||.| .|..|.|. . |.|.||. ..
gnkpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavlealdsfndei
|
|||||||||
subfamily_PTPN6_pd | Subfamily PTPN6 | 1245-1504 | 1.2e-77 | 255.9 | In-house | 27-301 (306) | alignment | ||
Range on Protein: 1245-1504
Range on HMM: 27-301/306.0
LFSEEYELITIK--SPSLPHEASQQTCNIEKNRYGNINSFDETRVVLTkIPGIEGSDYINANYID--GYGSRDTYIACQGPLAETSPDFWRMIWEQKTSC
|.||.| . . . | .. .... | ||||| || ||.|||.|. |.. ||||||||||. ||. .||| || | .| .|||||.|....
gfeeefeelqqeeakkllsrkegakpenkeknryknilPfDhtrvilk.epsvpgsdyinanyikkevkgsdksyiatqgclettvsdFWrmvwqensrv
IVMLTNCVEKGRPKCHQYWPQTGS-TTFGELTVTIIDQQVLAYYTIRTFKIN--NKDDESFEVKQFHYTAWPDFGVPDHPNPIISFIRRVNNST------
|||.|. ||.|. || .|||.. . ...|...|| .... ||.|..|..... .|..|. || |.|...||| ||| .|. ...|.. ||. .
ivmttkevErgkekCarYWPdeeekeeyGkisvtnvseksladYilRelsvskkkkkkeerevfqyhfksWPdhgvpkdpgavLdfledvnrkqeeleea
HTGPLVVHCSAGVGRSGTFIAIQSMMLMMETEG---KVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELIKVGN
..||.|||||||.|| |||| | .. ..|..| ..|. ..| .|. |. .||||.|| ||. .. . |. .
eagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqteqqykfvykaikkyietkk
|
|||||||||
subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 1565-1806 | 6e-77 | 253.8 | In-house | 44-287 (305) | alignment | ||
Range on Protein: 1565-1806
Range on HMM: 44-287/305.0
PVNRAKNRYPDILPYESYRVRLLMLPGVSGSDYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCGLVEDGKDQSVQYWPKDQLT--
.|.||||. .| ... |..| . . |||||||||||| | ...|..|||| |||.||||.|.| .|| ||||..|||.|||. ||||. .
eankaknrlkeitlldddriiltekeslddsdyinasyvdgykrkkkyivaqgPlkntvadfWrliveekvstivmltklveggkdkCrqYWpesktekk
QYGDMFIETISETDTGFYVIREITITHTKQGNEVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAHHLFGGGPVVVHDSSSVGRSGTFCIINIVIERL
..|.. .| ||. . |..|...|. .. .| |.. |.. ||| .. | ....|...| |||... | |..|| | .|||.|.|. ..| .|||
efgefsvelksektasdyieRklkisiededkesrtvlqyqltdWPdhGvpqfatsllslikrvqkdqkkdkgvpllVhCsagvgRtGvfiavdialerl
KVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYLESFD
| |...|.| ...||.|....| . ||. |... . |.....|
kkEevvdvfevlkqlRskrmkmvqtldqYvflhdaldelitcgd
|
|||||||||
subfamily_PTPN3_pd | Subfamily PTPN3 | 1249-1499 | 7.4e-77 | 253.0 | In-house | 20-274 (280) | alignment | ||
Range on Protein: 1249-1499
Range on HMM: 20-274/280.0
EYELITIKSPSLPHEASQQTCNIEKNRYGNINSFDETRVVLTKIPgieGsDYINANYID----GYGSRDTYIACQGPLAETSPDFWRMIWEQKTSCIVML
..| . | |.| .|.... |..|||| .| ..|.||| |.. . |||||||.. . | |||.|||||.|. |||.|.||||.| ||||
qfeqlyrkkpglaisaarkpenlsknryrdilpydatrvklkese...t.dyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqksslivml
TNCVEKGRPKCHQYWPQTG-STTFGELTVTIIDQQVLAYYTIRTFKINNKD-DESFEVKQFHYTAWPDFGVPDHPNPIISFIRRVNNST--HTGPLVVHC
|. ||.|| |||||||.|. ....||..|.. .. | .| . ...|. .|. .. |. |.|||| ||||... ...|..||.. .. |.||||
ttlverGrvkChqyWPetedeleygefsvkcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklrsgkeePvvvhC
SAGVGRSGTFIAIQSMMLMMETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVEL
|||.||.| .|... . ..|.. .| . . | || .| .|||..|| || ......
saGigrtGvlilletalalieaaepvypldivrtmrdqramlvqtasqykfvCeailkv
|
|||||||||
0040439 | (Phosphotyrosine protein) phosphatases II | 1559-1802 | 9.1e-77 | 253.3 | In-house | 3-246 (249) | alignment | ||
Range on Protein: 1559-1802
Range on HMM: 3-246/249.0
YISASLPVNRAKNRYPDILPYESYRVRLLMLPGVSGSDYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCGLVEDGKDQSVQYWPK
| |.||.|. ||||||||||.. ||.| |||. .||||||||.||| ....||.|||||..||.|||||.||.....||||. ||| |. . ||||
ysvallpenkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywpl
DQLTQYGDMFIETISETDTGFYVIREITITHTkQGNEVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAHHLF-GGGPVVVHDSSSVGRSGTFCIINI
.. ..|||......|.. . |..|....|.. . .|.| .....|||| . ..||.. |.|.| .|.||.. ||||.|| | |||.|||... .
ggsleygdftvtllsvevkddytvrtleltnl.ydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaayl
VIERLKVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYL
..|.|. |. .|.. ... ||.. ||.| |..|..|.|. . |.|
mleqlekelgvdleeavkllrsqRpgavqnpeqyrflyeallell
|
|||||||||
DSPc_SM00195 | 1543-1802 | 2.6e-75 | 248.5 | In-house | 4-262 (263) | alignment | |||
Range on Protein: 1543-1802
Range on HMM: 4-262/263.0
KQFEKLNSIDVAIpsQYISASLPVNRAKNRYPDILPYESYRVRLLMLPGVSGSDYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLC
..||||.. . . .| . |..|||| .||||.. ||.| .. .|||||||.|..|. . ...|.|||||..||.|||||.||..|. ||||.
eefekleestspk..etteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlt
GLVEDGKDQSVQYWPKD--QLTQYGDMFIETISETDTG-FYVIREITITHTKQgNEVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAHHLFgGGPVV
.|.|| . .|||.. . ...|.. ....... . ...|....|.... .| |...|..|..| ....| .| ..... |.| . ||.|
eeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegk.eetrkvtqyqyknWpdhgvpdstksvlellravkksksts.sgpiv
VHDSSSVGRSGTFCIINIVIERLKVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYL
|| | |||.|||. |.|....|. | ..||| .. .|| . ||.| . .|..|.|..|.||.
VhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi
|
|||||||||
PTPc_SM00194 | 1543-1802 | 2.6e-75 | 248.5 | In-house | 4-262 (263) | alignment | |||
Range on Protein: 1543-1802
Range on HMM: 4-262/263.0
KQFEKLNSIDVAIpsQYISASLPVNRAKNRYPDILPYESYRVRLLMLPGVSGSDYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLC
..||||.. . . .| . |..|||| .||||.. ||.| .. .|||||||.|..|. . ...|.|||||..||.|||||.||..|. ||||.
eefekleestspk..etteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlt
GLVEDGKDQSVQYWPKD--QLTQYGDMFIETISETDTG-FYVIREITITHTKQgNEVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAHHLFgGGPVV
.|.|| . .|||.. . ...|.. ....... . ...|....|.... .| |...|..|..| ....| .| ..... |.| . ||.|
eeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegk.eetrkvtqyqyknWpdhgvpdstksvlellravkksksts.sgpiv
VHDSSSVGRSGTFCIINIVIERLKVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYL
|| | |||.|||. |.|....|. | ..||| .. .|| . ||.| . .|..|.|..|.||.
VhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi
|
|||||||||
subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 1230-1526 | 3.6e-75 | 248.1 | In-house | 6-305 (439) | alignment | ||
Range on Protein: 1230-1526
Range on HMM: 6-305/439.0
MFPDYVKRLHANTDHLFSEEYELITIKSPSLPHEASQ--QTCNIEKNRYGNINSFDETRVVLTKIPGIEGSDYINANYIDGYGSRDTYIACQGPLAETSP
| ..|..|. | . .|.|..| | || .|| | . |||| .. .|| |||.| .|||. | |||||||.|| . |||.||| ||.
efqehvekldknkqeifkeifekinstspdyaciaslaaqeydqtknrykdvgafdhtrvtlqeipgvphshyinanyikGyyddklyiatqgpkkettd
DFWRMIWEQKTSCIVMLTNCVEKGRpkchqYWPQTGSTTFGELTVTIIDQQVLAYYTIRTFKINNKDDES---FEVKQFHYTAWPDFGVPDHPNPIISFI
||||...|.||. |||||| || . ||| . . .|...| . . | |.|| ||. |. | . | ||||.|||| || . .. |.
dfwrlviekktvtivmltnlvesyk.....ywpsdaevcygdiavrvdrnielpnyvirgfkvfnerdttekertvlqfhyiawpdknvpaqashvldfl
RRV---NNSTHTGPLVVHCSAGVGRSGTFIAIQSMMLMMETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELIKVGNSEQTVQNFPKEAKILLT
| . |.. .||.||||||||||.|| ||.. . . .| |||. | .|..|. |||. .||.|......| |. |. |...| || . ..
rainsandkeeygpvvvhcsagvGrtGtiialdialeqlklenkvdikgivkvlrkqrkqmvqalcqyvfiynavledivyGdiavtidefkkefnagfs
TQEDN
|.. .
trdis
|
|||||||||
subfamily_PTPRA_pd | Subfamily PTPRA | 1546-1802 | 4.1e-75 | 247.7 | In-house | 36-295 (330) | alignment | ||
Range on Protein: 1546-1802
Range on HMM: 36-295/330.0
EKLNSIDV-AIPSQYISASLPVNRAKNRYPDILPYESYRVRLLMLPGVSGSDYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCGL
|..|.. | . . || |. |||...||||. || | .. || |||||||..||| . ..|| .|||...||.||||||||.. ..|||| |
eefnalPagpiqatlelaskeenkeknrvvnilPydfsrvilsvkeGveesdyinasfidGykekdkfiaaqGPkeetvedfwrmiweqksativmltel
VEDGKDQSVQYWPKDQLTQYGDMFIETISETDTGFYVIREITIT---HTKQGNEVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAHHLFGGgPVVVH
| ... ||||.. | ||.. .| || . | .|.. .. .... ...| ..|||.| | . | .. ..... |.| .. .| |.|||
kerkeekcaqywPdeGlvtyGnirvevedetvlvdytvrkflvqqlpdatrekksrlvrqfhftswPdvGvPfepiGmlkllkkvkklnqqsag.pivvh
DSSSVGRSGTFCIINIVIERLKVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYL
|. |||.|||.... |.||.| |...|.| ... || . | .| |..|.|... ||
csaGvGrtGtfivldavlervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvlleyy
|
|||||||||
subfamily_PTPRG_pd | Subfamily PTPRG | 1541-1805 | 7.2e-75 | 247.3 | In-house | 21-290 (563) | alignment | ||
Range on Protein: 1541-1805
Range on HMM: 21-290/563.0
LPKQFEKLNSIDVAIPSQYISASLPVNRAKNRYPDILPYESYRVRLLMLPGVSGS-DYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIV
. ..||.|.| .. .. ... | |. |||| .|..|.. ||.| |||. .. |||||.|.||| . ..||.||||| .|.|||||||||..|. ||
fseefealqsetiskdldaehsqkpenkrKnRylnivaydrsRvklsplpgkkkklDYinAnyidGyqkskafiatqgplkdtfddFWrmiWeqnvaiiv
MLCGLVEDGKDQSVQYWPKDQLTQYGDMFIETISETDTGFYVIREITITH-----TKQGNEVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQkAHHLFG
|. |||.|. . .|||||. .|| . . |.| . | .|...| . .|| .......|.|||.| . .| . . ... . | .
mitnlvergrrkcdvYWPkdesetygalqvtlieeevlalytvrtlviknlklkkkkqcdteklvrqyhytkWPdhgvPehslpvLifvkkss.aankae
GGPVVVHDSSSVGRSGTFCIINIVIERLKVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYLESF
||.|||.|. |||.||..... ...... | ....| ... .| . . .|.. .|. | .....| . |
aGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvqteEqYiflhdalleaiask
|
|||||||||
0045098 | (Phosphotyrosine protein) phosphatases II | 1545-1805 | 1e-74 | 246.7 | In-house | 11-275 (278) | alignment | ||
Range on Protein: 1545-1805
Range on HMM: 11-275/278.0
FEKLNSIDVAIPSQYISASLPVNRAKNRYPDILPYESYRVRllmlpgvsgsDYINASYVDGYlRcNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCGL
| . . |||.. | .. |..||||.|||||.. ||. |||||||.||| . ..||.||||| .||.|||||.||.....||||..|
lefefllllgipseitpalylgnldknRykdilpydhsrVk..........dYINAsyidgy.p.kkfIatqgPlpstvadfwrmlwelgitvivmltel
VEDGKDQSVQYWPKDQLTQYGDMFIETISETDTGFYVIREITITHT---KQGNEVRNIKQFHYTDWSENKTPPTT--GALMDMIVLVQKAHH--------
||.|. .|||| .. .|||......||. .. |..| ...|.. ....| |.....||. | .. .|... . ... ...|.
velgrekcaqywpeggsltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllasllls
----LFGGGPVVVHDSSSVGRSGTFCIINIVIERLkvEGMIDIFFTIHALRRKHPG-IVANYDQFKFCYQTIVEYLESF
| .||||.|| | |||.||.... ...|.| || .|.. ... ||.. || .| | .|..|.|. ..|.|. .
slllldsggpvlVHCsaGvgRtGtlvaaylmlell..eggvdlleavkelrsqRpglavqnleqyrflyefllelllrg
|
|||||||||
0042113 | (Phosphotyrosine protein) phosphatases II | 1562-1803 | 2.5e-74 | 245.1 | In-house | 4-244 (245) | alignment | ||
Range on Protein: 1562-1803
Range on HMM: 4-244/245.0
ASLPVNRAKNRYPDILPYESYRVRLLMLPGVSGSDYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCGLVEDGKDQSVQYWPKDQL
|.||.|. ||||.|||||.. ||.| .| .|||||||||||| ....||.|||||..||.|||||.||.....||||. ..|.|. .. |||| ..
allpenkdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywplges
TQYGDMFIETISETDTGFYVIREITITHtKQGNEVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAHHLFGGGPVVVHDSSSVGRSGTFCIINIVIER
..|||......||. . |..|....|. .. .|.|.. ..||..| ....|... | |.. .|.|| . ..|||.|| | |||.|||... ...|.
ltygdftvtllseehlddytvrtlevtn.lgddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleq
LKVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYLE
|. |. .... ... ||.. ||.| . .|..|.|. . |.|.
lekelgvsleeavkelrsqRpgavqtpsqyrflyeallellk
|
|||||||||
subfamily_Ptp69D_pd | Subfamily Ptp69D | 1543-1803 | 1.1e-73 | 243.0 | In-house | 26-287 (307) | alignment | ||
Range on Protein: 1543-1803
Range on HMM: 26-287/307.0
KQFEKLNSIdvAIPSQYISASLPVNRAKNRYPDILPYESYRVRLLMLPGVSGSDYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLC
| .|||.. |. . . | ||||.|| .....||.| ..| |||||||.. || ..||. |.|. .|..||||||.| | ||||
keyekLear..eidkstkvsekkenalknRyedikafDktRvkLkkingkedsdYinasfikgykekkkfiaaqdPveatigDfWRmiaeqevtlivmls
GLVEDGKDQSVQYWPKDQLTQYGDMFIETISETDTGFYVIREITITHTK-QG---NEVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAHHLFgGGPV
| | ... .|||... .||||. ....|| .. |.|||. ....| .. .. |.. |.||| | . | | .. .|...| |.. ..| .|.
nlteknrkkcakYWpiedevqygdilvklvseekhsdyiiReldvskkkeesgevedsrkvvqyhytgWkDskvPevargllklieqvrelykln.rsPi
VVHDSSSVGRSGTFCIINIVIERLKVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYLE
||| | |||||.| .......|| | .||| |.. ||.. . .| ...|..|.|. ...| .
vvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnllvqsleqYvflyralldyss
|
|||||||||
subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 1225-1530 | 1.2e-73 | 243.1 | In-house | 4-315 (325) | alignment | ||
Range on Protein: 1225-1530
Range on HMM: 4-315/325.0
SISVSMFPDYVKRLHANTDHLFSEEYELITIKSPSlPHEASQQTCNIEKNRYGNINSFDETRVVLTKIPGIEGSDYINANYIDGYGSRDTYIACQGPLAE
||.| . ..|.. .|. . |. |..|. . . .... . |..|||. |. ..|..|||| ||||||.|. . .|...|.| ||..
siavvnlvehvekkkaqdqdgfahefgllpsddgi.akkvamkpenkaknrfknvvaldksrvvletkkddpssdyinasylrddkkkdvflaaqaPlta
TSPDFWRMIWEQKtSCIVMLTNCVEKGRPKCHQYWPQT--GSTTFGELTVTIIDQQVLAYYTIRTFKINNK-DDESFEVKQFHYTAWPDFGVPDHPNPII
| |.||.. . . . .|...| ...| .| .|||. | ||| | | .. . .. | | ... . . |. ||||.. .|.|.||. .| .|
tindlWrlvldWr.csvvvvlneldlgkdrcavywpkemgksktfGglevklrtieeisdyvhrvldvkqvkkGetrsvkqfqlqswddmGvqkrpatli
SFIRRVN--------NSTHTGPLVVHCSAGVGRSGTFIAIQSMMLMMETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELIKVGNSEQTVQNFp
|... |. |. ..|..|||||||||.|.||.. |.. . .| .||.|.|| .|..| ||.| ||......||| . ||.. | .|
silqlvkavservtantkastpilvhcsaGvGrtGvfislysalakvieesrvdifgfvkklrkdrpsmvetvdqyiliyealveaymsgntdvpvssf.
kEAKiLLTTQEDNNIED
||| | . || | . .
.eak.lsslqernpltq
|
|||||||||
subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 1227-1507 | 1.3e-73 | 242.9 | In-house | 3-283 (515) | alignment | ||
Range on Protein: 1227-1507
Range on HMM: 3-283/515.0
SVSMFPDYVKRLHANTdhLFSEEYELITikSP-SLPHEASQQTCNIEKNRYGNINSFDETRVVLTKIPGIEGSDYINANYIDGYGSRDTYIACQGPLAET
.. || .|.. | |||||. . | | .|. | .||||.|| .| .|| | | |||.|| || .. . .||| |||. .
plaqfPafvnknrhtt..lfseefhdlp..gpniypqtvaqeeinfkknryknilPydsvrvklevindnPhsdyfnasyipsfdndkayiasqgPnkas
SPDFWRMIWEQKTSCIVMLTNCVEKGRPKCHQYWPQ--TGSTTFGELTVTIIDQQVLAYYTIRTFKINNKDDeSFEVKQFHYTAWPDFGVPDHPNPIISF
||||........ |.|.|. | . || .|||. . | ||.. | .. . . ..|.... || | | |||.| ||| ||| | . .. .
vddfWrlvlqenvttiamvtklkegdkikcgkyWPdkpgdsvkfGsikvelvsleactggikrkltvlkgdd.srtvtqfhfteWPdkGvpkhtssllkl
IRRVNNST--HTGPLVVHCSAGVGRSGTFIAIQSMMLMMETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELIKVGNSEQ
|. | .. | ||..|||||||| | .|.|.|.. ..| ||||||| .| || |.|||. || |... . | .. |.
ikevkadhgqythpliihcsaGvGrtGvvisidsvvahakttrmvdvfnfvtnirqkrpylvqtqeqyafiygavledllwrntli
|
|||||||||
subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 1224-1521 | 1.5e-73 | 242.4 | In-house | 1-298 (315) | alignment | ||
Range on Protein: 1224-1521
Range on HMM: 1-298/315.0
QSISVSMFPDYVKRLHanTDHLFSEEYELITiKSPSLPHEASQQTCNIEKNRYGNINSFDETRVVLTKIPGIEGSDYINANYIDGYGSRDTYIACQGPLA
| | |. || .|.. . |||||. . . .. ....| | .||||.|| .|..||.| | . |||||| || .. . .||| ||||
qpipvaqfpafvnknr..htalfseefhdlp.dPdiyrqrvaretinfkknryknilPldsarvkleviddsPdsdyinasyiksvdddkayiasqgPlk
ETSPDFWRMIWEQKTSCIVMLTNCVEKGRPKCHQYWPQ--TGSTTFGELTVTIIDQQVLAYYTIRTFkINNKDDESFEVKQFHYTAWPDFGVPDHPNPII
. |||||....|.. |||.|. | . || ||||. . |. ||.. |.... . . ..| . . | .|| | ||..| ||| ||. . ..
asvddfwrmvlqekvttivmvtkkqegdkikcrqywPdrkadsvefGsikvellsleadtdgvarkl.vtrkseesrtvtqfqftewPdkGvdkqtssll
SFIRRVNN--STHTGPLVVHCSAGVGRSGTFIAIQSMMLMMETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELIKVGNSEQTVQNFPKEAKIL
.|. | ... .|.|||||||||.| .|.|.... .. . ||||||| .| || |.|||| .| |..|.. | .. |. .| .| . |
klikevkadngkkefsllvhcsaGvGrtGvvisidevvaqikrtrsvdvfnfvknlrakrpylvqteeeyafiydavledllwrntlilvihftdhlqdl
LT
|
ht
|
|||||||||
subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 1545-1801 | 2.8e-72 | 238.7 | In-house | 40-291 (319) | alignment | ||
Range on Protein: 1545-1801
Range on HMM: 40-291/319.0
FEKLNSIDVAIPSQYiSASLPVNRAKNRYPDILPYESYRVRLLMLPGVSGSDYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCgl
| .. . | | | |. |. |||. .||... .|.| | |. .|||||||.|.|| | ...| .|||| ||..||||||||...|.||.|
frracklgvnladqt.fanldqnkdknriinilafdknvvklerliGeefsdyinasfvtGyqrkdkyiaaqGPldntladfWrmiweyncstivllt..
vedgKDQSVQYWPKDQLTQYGDMFIETISETDTGFYVIREITITHTKQGNEVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAHH-LFGGGPVVVHDS
||. ||||.. ... . .. | ..| ||.|.| ... . ...|.|.|||. | . | . || .. |.. .. . ..||| |
....kdkcsqywplkivikeerfkvkvdsveetaeyvvrdielsedgkekdirkitqfhflGwpdvGvpdypsdlmrlvkkvrhltskenhranivvhcs
SSVGRSGTFCIINIVIERLKVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVE-Y
. |||.|.. .......|.| | ..|.. ... ||.. . .| .. |.||.| ...| .
aGvGrtGvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleeh
|
|||||||||
subfamily_PTPRB_pd | Subfamily PTPRB | 1543-1804 | 8.8e-72 | 236.6 | In-house | 29-287 (293) | alignment | ||
Range on Protein: 1543-1804
Range on HMM: 29-287/293.0
KQFEKLNSIDVAipSQYISASLPVNRAKNRYPDILPYESYRVRLLMLPGVSGSDYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLC
...|.|.... . .|.|.|||||||| .||||. ||.| | . ||||||||.|..|| ..|| ||||| .||||||||.||...|.||||
eeyeelkavgkd..qavkaaelavnraknrytnilpydhsrvkLaalkdesgsDYinanyipgynsprefiatqGPlpetvddfWrmvwekkssiivmlt
GLVEDGKDQSVQYWPKD-QLTQYGDMFIETISETDTGFYVIREITITHtkqGNEVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAH-HLFGGGPVVV
||| || . .|||.| . ..|||. .. ..|... .||||..|.. ..| |...|.|.| |.. | .| .|.|.. |..|. . .|.||
qlvekgkvkCeeYWPadeepvlyGdikvtlvaeeeledwvirelkiek...ekeerkvrqyhftsWpdhgvPektktlldfvrtvreaiektaskrPivv
HDSSSVGRSGTFCIINIVIERLKVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYLES
| |. |||.||| .. ...... | ..||| ....||.. .| . .|. | .|.....|..
hCsaGvGRtGtfialdrllqaieeedyvdifgivaelReeRnllvqtekqYifihqcvldllrk
|
|||||||||
subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 1564-1810 | 2e-71 | 235.1 | In-house | 6-250 (250) | alignment | ||
Range on Protein: 1564-1810
Range on HMM: 6-250/250.0
LPVNRAKNRYPDILPYESYRVRLLMLPGVSGSDYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCGLVEDGKDqSVQYWPKDQLTQ
| |. |||| ||....| || | | |||||||...|| . ||.|||||..|. |||||..|. ...|||| |.| .| |||| .. ..
kpqnkeknryadiialdssrvvLekekgdkesdyinasflhgyderkafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqywPvekaek
YGDMFIETISETDTGFYVIREITITHTKQGNEvRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAHHLFGGGPVVVHDSSSVGRSGTFCIINIVIERLK
|||. .. |. . |..|.. ....|. .| | ..|.|.. | . | .. | .... ||. . | .||.|. |. |||||.|..|. |.||||
yGdvtvsllskeefadytkrklklskakkade.rivrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidavlerlk
VEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYLESFDKYAN
| ..|.| |..||.. |. | .|. |.|. | ..|.|.. ||.
kekvvdvfkvikvlrkdrphavesleqyvfvyeiilkaldsvedyar
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 1567-1800 | 2.1e-71 | 235.5 | Pfam-A | 1-235 (235) | alignment | ||
Range on Protein: 1567-1800
Range on HMM: 1-235/235.0
NRAKNRYPDILPYESYRVRLlmlPGVSG-SDYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCGLVEDGKDQSVQYWP--KDQLTQ
|. ||||.|||||.. ||.| | .| ||||||.||.|| . ..||.|||||..|..|||||.|...|..||||. |.| |. . |||| ... ..
nkkknRykdilpydktrvkl...kgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeeslt
YGDMFIETI-SET-DTGFYVIREITITHTKQGNEVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAHhLFGGGPVVVHDSSSVGRSGTFCIINIVIER
|||...|. .|. |. |..|.......|. .| | .||.|||.| ....| .. .|.|.| |.| . |||||| | |||.|||. ..|..|.
ygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkveksk.eaksgpvvVhCsaGvgRtgtfvaldilleq
LKVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVE
|. |. .|.. .. ||.. ||.| ...|..|.|..|.|
leaeeevdvlqivkelRkqRpgmvqsleqYiflykaile
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 1567-1800 | 2.1e-71 | 235.5 | In-house | 1-235 (235) | alignment | ||
Range on Protein: 1567-1800
Range on HMM: 1-235/235.0
NRAKNRYPDILPYESYRVRLlmlPGVSG-SDYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCGLVEDGKDQSVQYWP--KDQLTQ
|. ||||.|||||.. ||.| | .| ||||||.||.|| . ..||.|||||..|..|||||.|...|..||||. |.| |. . |||| ... ..
nkkknRykdilpydktrvkl...kgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeeslt
YGDMFIETI-SET-DTGFYVIREITITHTKQGNEVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAHhLFGGGPVVVHDSSSVGRSGTFCIINIVIER
|||...|. .|. |. |..|.......|. .| | .||.|||.| ....| .. .|.|.| |.| . |||||| | |||.|||. ..|..|.
ygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkveksk.eaksgpvvVhCsaGvgRtgtfvaldilleq
LKVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVE
|. |. .|.. .. ||.. ||.| ...|..|.|..|.|
leaeeevdvlqivkelRkqRpgmvqsleqYiflykaile
|
|||||||||
subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 1561-1801 | 2.3e-71 | 235.6 | In-house | 19-255 (284) | alignment | ||
Range on Protein: 1561-1801
Range on HMM: 19-255/284.0
SASLPVNRAKNRYPDILPYESYRVRLLMLPGVSGSDYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCglvedgKDQSVQYWPKDQ
| |. |. |||. .||... .|.| | |. .|||||||.. || | ...| ||||| ||..||||||||...|.||.| ||. ||||..
fanldqnkdknrighilafdknvvklerliGeefsdyinasfitGyqrkdkyiatqGPldntladfWrmiweyncstivllt......kdkcsqywplki
LTQYGDMFIETISETDTGFYVIREITITHTKQGNEVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAHH-LFGGGPVVVHDSSSVGRSGTFCIINIVI
... . .. | ... ||.|.| ... . ...|.|.|||. | . | . || .. |.. .. . ..||| |. |||.|.. ......
vikeerfkvkvdsveeseeyvvrdielsedgkekdirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrtgvyivldvll
ERLKVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVE-Y
.|.| | ..|.. ... ||.. . .| .. |.||.| ...| .
drmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleeh
|
|||||||||
subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 1543-1801 | 3e-71 | 234.8 | In-house | 25-278 (288) | alignment | ||
Range on Protein: 1543-1801
Range on HMM: 25-278/288.0
KQFEKLNSIDVAipSQYISASLPVNRAKNRYPDILPYESYRVRLLMLPGVSGSDYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLC
.....| ... .. ..|.|| ||||..||||. ||.| |. ..|.|||||||.||. . ...| ||||| .||.|||....|...| ||||
eeynsLaalekt..ksvtagrlavnakknRyrnilpyDekrvklkkleeeagaDYinasyidgekkkkkyiatqgPladtvndfWelvyenktstivmlt
GLVEDGKDQSVQYWPKDQL-TQYGDMFIETISETDTGFYVIREITIThtKQGNEvRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAHHLFgGGPVVVH
.|||.|| . .|||... ..||.. .. ... ... .| |.. . |...| ..|.|..|. |.... | . |.... |. |.. ||..||
elveggktkCeeYWPdadkpknyGsvtvtlveskeledfvlrkllle..kkkte.leitqyqylaWpdhgvPeskapllellrqvkvanqad.tgpiivh
DSSSVGRSGTFCIINIVIERLKVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEY
| |||.||| .. .|.... | .||.. |.. ||.. . .| . |. |.|.....
CsaGvGrtgtFialdalidaveeedyiDvagtvaklRkqRallvqtlkqYefiyevllsl
|
|||||||||
subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 1226-1500 | 7.2e-71 | 233.4 | In-house | 2-283 (290) | alignment | ||
Range on Protein: 1226-1500
Range on HMM: 2-283/290.0
ISVSMFPDYVKRLHANTDHLFSEEYELITIKSPSLPHEASQQTCNIEKNRYGNINSFDETRVVLTKIPGIEG--SDYINANYIDGYGSRDTYIACQGPLA
| |. | ..| ||. .. | .... . . . . . | ..||. || |. |..| .|.| . .|||| ||.|| . ||| |||.
ipvdkfgefvanghakgnegfrnqfkmldsgesehtvtvgltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgykekkqyiatqgpvs
ETSPDFWRMIWEQKTSCIVMLTNCVEKGRPKCHQYWPQTGSTTFGELTVTIIDQQVLAYYTIRTFKINNKDD--ESFEVKQFHYTAWPDFGVPDHPNPII
.| |||..||..|...|||||| .|.|. ||.||||.......|| .........| .|..|.....||. .. .|.|.. |.|.. | .|. |.
ntlvdFWkliwqekvtiivmltniieegkvkCqqYWpdsdtkaygefsikllneetlneyierklevknknsagakqsvtqyqitnwdstgkvtnpqtil
SFIRRVNN---STHTGPLVVHCSAGVGRSGTFIAIQSMMLMMETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELI
. |..... . ...|||||..||||..|.|.. . ..||| .|||. . .| .. .|||. || .... ... .
lvieemyktqrkrgntsivvHCSdtvgrsavfcaaattinkcktegvidvfqvlksqRiqkpgsvqtvqqyqgifqivltyl
|
|||||||||
subfamily_PTPRK_pd | Subfamily PTPRK | 1564-1800 | 7.2e-71 | 233.6 | In-house | 40-275 (314) | alignment | ||
Range on Protein: 1564-1800
Range on HMM: 40-275/314.0
LPVNRAKNRYPDILPYESYRVRLLMLPGVSGSDYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCGLVEDGKDQSVQYWPKDQLTq
||.|||. |||.|. ||.| . | . ||||||...|.| | ..||.||||| .|| ||||...... ..|||| ||| |. . ..|||.| .
kdenreknrsgdilaydrsrvflitidgdpssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasivmltelvevgrvkClkyWPedtev.
YGDMFIETISETDTGFYVIREITITH-TKQGNEVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAHHLfGGGPVVVHDSSSVGRSGTFCIINIVIERL
|||. .| .. . .|.| .... ... .|.| ..||... |.. ..| .|.... |.| .. . |..||| |. ||.|||..|.||.. .
ygdikvelvetellaelvvrifrveklargqeeirevrqfqflgWpdhdvPvsatgllklvrrvkksqee.eaGrivvhCsaGaGrtGtfiaidivldmi
KVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVE
. ||..|.|.....|| ... .| .|.||.|. |.|
eregvvdvfnavktlrsrkvnmveteeqykfiydvile
|
|||||||||
subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 1226-1505 | 1.1e-70 | 232.9 | In-house | 2-283 (287) | alignment | ||
Range on Protein: 1226-1505
Range on HMM: 2-283/287.0
ISVSMFPDYVKRLHANTDHLFSEEYELITI---KSPSLPHEASQQtcNIEKNRYGNINSFDETRVVLTkipgIEGSDYINANYIDGYGSRDTYIACQGPL
|.|..| ..|.. ||. . |.. . .. . .. |. ..| | .|||. .| |. ||.| | ||||| .|||| .. .|....|.
ipvekfgefvakghakgnegfknqftvleqvtqredevthniasq..nkdknRltqilvpdnyrvllk....gehpdyinavfidgykekkafiiaesPm
AETSPDFWRMIWEQKTSCIVMLTNCVEKGRPKCHQYWPQTGSTTFGELTVTIIDQQVLAYYTIRTFKINN--KDDESFEVKQFHYTAWPDFG-VPDHPNP
..| .||..|.... . ||||.. |. . .|.||||.. |...|| ........| | |..|.....| |... .|||...|.|.. | |...
fntarnfWkliddrnvtaivmlcqekendeevcyqyWpeeksvvlGeyniellneevnagyierklevknknkagdkqqvkqyqitnWdstgkvtepqti
IISFIRRVNNSTH--TGPLVVHCSAGVGRSGTFIAIQSMMLMMETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELIKVGNS
.. . ... . . ...|||||..||||..|.|.. . .||| .|||. . .| .. .||| .||.|. | ..| .. ..
llvieemyktqrkrgntsivvhCsdtvGrsamfcaaattinkckteGviDvfqvlksqriqkpgsvqtveqykfindivleyldsfet
|
|||||||||
subfamily_PTPN1_pd | Subfamily PTPN1 | 1242-1514 | 2.2e-70 | 231.7 | In-house | 4-285 (290) | alignment | ||
Range on Protein: 1242-1514
Range on HMM: 4-285/290.0
TDHLFSEEYELITIKSPSLPHEASQQTCNIEKNRYGNINSFDETRVVLTKipgiEGSDYINANYIDGYGSRDTYIACQGPLAETSPDFWRMIWEQKTSCI
...|..| |. |. .. .|...... | ..||| ... .| .|..| . . |||||. .. . || ||||..| ||.|.||||. ..
kkrlykeiyldirkeasdfptreaklpenrnlnryrdvspydhsrikler....adndyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskav
VMLTNCVEKGRPKCHQYWPQTGS---TTFG--ELTVTIIDQQVLAYYTIRTFKINN-KDDESFEVKQFHYTAWPDFGVPDHPNPIISFIRRVNNS----T
||| ..|||.. ||.||||| . .. .|.|..| ... |||.|.....| | .|. |. .||||.|||||||. |. ..|. .| .| .
vmlnkvvekeqikcaqywPqgeeekellledtklkvkliseerksyytvrllelenlktqetreilhfhyttwpdfgvpespaaflkflfkvresGslss
HTGPLVVHCSAGVGRSGTFIAIQSMMLMMETEGK---VDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELIKVGNSEQTVQNFPK
. || |.|||||.||||||. . .... .| ... ||. . .|..|. | ..|| | | . ...| .|| ... .||. |
dvGpavihcsaGiGrsGtfclvdtclvliekkddlssvdikkvllelrkyrlGliqtadqlrfsylaileGakvikgdssvqkrwk
|
|||||||||
subfamily_PTPN13_pd | Subfamily PTPN13 | 1247-1501 | 2.4e-69 | 228.6 | In-house | 14-270 (273) | alignment | ||
Range on Protein: 1247-1501
Range on HMM: 14-270/273.0
SEEYELITIKSPSLPHEASQQTCNIEKNRYGNINSFDETRVVLTKIPGiegsdYINANYIDGYGSRDT--YIACQGPLAETSPDFWRMIWEQKTSCIVML
.||.. . | . | ... | .|||| |. .||||| | . | ||||..| |. |||||||| || |||.|.||||.. |.|.
aeefkelrelkpldtcevgkkkenkdknryrnvlPydetrvklgdegg.....yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamv
TNCVEKGRPKCHQYWPQTGSTT---FGELTVTIIDQQVLAYYTIRTFKINN-KDDESFEVKQFHYTAWPDFGVPDHPNPIISFIRRVNNSTH-TGPLVVH
|. .|||. |||.|||.. . . . |.|. ...| | ...|...... . || || ......||| ||| ...... |...|.. . .||.|||
tlekekgkvkchrywPesknkklkvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaellqfvaevrrlqtdagPivvh
CSAGVGRSGTFIAIQSMMLMMETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELIK
||||.|||||.|.|. .. ..| . ..|| . | ..|..|. .|||. ||.||. ...|..|
csaGiGrsGtlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykailevlk
|
|||||||||
subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 1265-1500 | 3.4e-68 | 224.7 | In-house | 23-268 (274) | alignment | ||
Range on Protein: 1265-1500
Range on HMM: 23-268/274.0
SQQTCNIEKNRYGNINSFDETRVVLT-KIPGIEGSDYINANYIDGYGSR-DTYIACQGPLAETSPDFWRMIWEQKTSCIVMLTNCVEKGRPKCHQYWPQT
. . . .|||| .| ...||.|. . . | |.||||||| ||. . .|.| ||||..| ||||||...... |||||. |. . ||..|.|..
ldvfgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneqkCavyfPda
GST----TFGELTVTIIDQQVLAYYTIRTFKINNKDDeSFEVKQFHYTAWPDFGVPDHPNPIISFIRRVNNS-----THTGPLVVHCSAGVGRSGTFIAI
.. ..|.. ... . |..|.. ... . . .|| . ||.||| .||..|....... |..| ....| |||||||.|| | ||||
edyeiserygdveikvekiverndysvrklvlkyler.ersvkhywytdWPdhksPddantlldlvleveesreeenaklapvvvhCsaGiGrtGcfiai
QSMMLMMETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELI
. . .. |..|||.. | ..| .| ||||. || ..| |..
siavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralclyl
|
|||||||||
subfamily_PTPN12_pd | Subfamily PTPN12 | 1561-1803 | 3.5e-67 | 221.3 | In-house | 34-278 (290) | alignment | ||
Range on Protein: 1561-1803
Range on HMM: 34-278/290.0
SASLPVNRAKNRYPDILPYESYRVRLLMLPGVSGSDYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCGLVEDGKDQSVQYWPKD-
... ..|..|||| |||||. || | .. |||||||... | ..| .||||..|.|||||||||..|. .||.| .|| || . .|||.
agekeenvkknrykDilPydksrvelskieeeegsdYinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCerYWpeeg
-QLTQYGDMFIETISETDTG-FYVIREITITHTkqgNEVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAHHlFGGGPVVVHDSSSVGRSGTFCIINI
. ...|.. .....| . ..|| ..... .| |...|||||.| . .| .. |...| ||.. .. |.||| |. ||| || . |..
eeelefgefevtleeekavdddflirtLkveaq...kesrkvyqfhYtaWPDhgvPssaksllelielvrelqe.sedaPlvvhCsaGvGrtGtiiaidy
VIERLKVEGM---IDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYLE
| | || | . .|.| . ||.. . .| .|... |....|...
vrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelvq
|
|||||||||
0037934 | (Phosphotyrosine protein) phosphatases II | 1561-1802 | 3.7e-67 | 221.7 | In-house | 4-242 (243) | alignment | ||
Range on Protein: 1561-1802
Range on HMM: 4-242/243.0
SASLPVNRAKNRYPDILPYESYRVRLlmlpgvSGSDYINASYVDGYlrcNQFIMTQGPLSNTVDD----FWRMIWEHRVSAIVMLCGLVEDGKDQSVQYW
|.||.|. ||||.|||||. ||.| .|||||||...... ...| |||||..||.| ||||.||.....||||. ||| |. . .|||
iallpenlsknrysdilpydhsrvkl......egsdyinanliyvt...prliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqyw
PkDQLtQYGDMFIETISETDTGFYVIREITITHTKQGNEVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAHHL-------FGGGPVVVHDSSSVGRS
| .. .|||......||. .. |..|........ ....|.. ..||. | ....|... |.|.. |.. . .||||.|| | |||.
p.gev.tygdftvtllseehlddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRt
GTFCIINIVIERLkveGmIDIFFTIHALRRKHPG-IVANYDQFKFCYQTIVEYL
||.... .....| | .|.. ... ||.. || .| ...|..|.|. . |.|
Gtliaaylmllll...g.vdleeavkllreqRpgkavqtpsqyrflyeallell
|
|||||||||
subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 1222-1509 | 3.4e-66 | 218.4 | In-house | 6-293 (297) | alignment | ||
Range on Protein: 1222-1509
Range on HMM: 6-293/297.0
QRQSISVSMFPDYVKRlhANTDHLFSEEYeLITIKSPSLPHEASQQTCNIEKNRYGNINSFDETRVVLTKIPGIEGSDYINANYIDGYgsRDTYIACQGP
.|. | .| |. .|.. ..||||. | . .. | ... |.||.|| || .| || | . |||.|| .. |. . .|. | |
errpiplsdfatlvqk..nrhtdvfseef.lclpeaniqpqtvaekkvnfeksRYkniLPydssRvkLaivnddpdsDyvnasfvkgn..khrlittqmP
LAETSPDFWRMIWEQKTSCIVMLTNCVEKGRpKCHQYWPQTGSTTFGELTVTIIDQQVLAYYTIRTFKINNKD-DESFEVKQFHYTAWPDFGVPD--HPN
.| |||.|......| ||||.. |. . || .||...|.||||...|.. . . |...... . |||.... ||| |. . .
mkatvadfWamvldeqvstivmlnddnerdk.kcaryWsdkgvttfGdvsvvllsvsereGfikrelevtkgkakarrvvkqyqfveWPdkaverkdsas
PIISFIRRVNNS---THTGPLVVHCSAGVGRSGTFIAIQSMMLMMETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELIKVGNSEQTV
.. .| |... . |||.|||.||||| | ...|.|.. .. | .||.|..| .|..| |.|||. || ||. ..| . . . .
sllklisevrkdfsqnaegPllvhclaGvGrtgvlltidsvvaeakrekevdifglvkklrqerpylvqtkeqykfvyvavleallsedtriqa
|
|||||||||
subfamily_PTPN6_pd | Subfamily PTPN6 | 1541-1807 | 2.2e-65 | 215.7 | In-house | 28-302 (306) | alignment | ||
Range on Protein: 1541-1807
Range on HMM: 28-302/306.0
LPKQFEKLNSIDVAIPSQYISASLPVNRAKNRYPDILPYESYRVRLLmLPGVSGSDYINASYVDGYLR--CNQFIMTQGPLSNTVDDFWRMIWEHRVSAI
. ..||.|. .. . .. | |. |||| |||.. || | |.|.|||||||.|... .. ....| ||| |..|| |||||.|. |
feeefeelqqeeakkllsrkegakpenkeknryknilPfDhtrvilk.epsvpgsdyinanyikkevkgsdksyiatqgclettvsdFWrmvwqensrvi
VMLCGLVEDGKDQSVQYWPKDQ-LTQYGDMFIETISETDTGFYVIREITITHTKQGNEVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAHHLFG---
||. || ||.. ..|||. . ..||.. ....||... |..||......|...| |.. |.|...| .. .| .||..|.. |.. .. .
vmttkevErgkekCarYWPdeeekeeyGkisvtnvseksladYilRelsvskkkkkkeerevfqyhfksWPdhgvpkdpgavLdfledvnrkqeeleeae
GGPVVVHDSSSVGRSGTFCIINIVIERLKVEGM---IDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYLESFDK
||.||| |. .|| ||| .|.|... .. .|. ||| ... .|. . |.| .|.|| |..| .|.|. |
agpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqteqqykfvykaikkyietkkk
|
|||||||||
subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 1544-1811 | 3.9e-65 | 214.7 | In-house | 25-287 (287) | alignment | ||
Range on Protein: 1544-1811
Range on HMM: 25-287/287.0
QFEKLNSIDVAiPSQYISASLPVNRAKNRYPDILPYESYRVRLLmlpgVSGSDYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCG
|| |.... . . . . |. |||. .||... ||| | |||||...||| ..||....|..||. .||..|....|.||||||
qftvleqvtqr.edevthniasqnkdknRltqilvpdnyrvllk....gehpdyinavfidgykekkafiiaesPmfntarnfWkliddrnvtaivmlcq
LVEDGKDQSVQYWPKDQLTQYGDMFIETISETDTGFYVIREITITHTKQGNEVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAHHLFGGGPVVVHDS
. |. ... ||||... . .|. || ..|. . |..|.. ...... .. ...||...|.| .. .. . . .| |... | ...||| |
ekendeevcyqyWpeeksvvlGeyniellneevnagyierklevknknkagdkqqvkqyqitnWdstgkvtepqtillvieemyktqrkrgntsivvhCs
SSVGRSGTFCIINIVIERLKVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYLESFDKYANF
.||||..|| ... |.. | || ||.| .. | ..|| | .|.|| .. ..|||.||. |..|
dtvGrsamfcaaattinkckteGviDvfqvlksqriqkpgsvqtveqykfindivleyldsfetysdf
|
|||||||||
subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 1270-1498 | 4.9e-65 | 214.1 | In-house | 3-237 (237) | alignment | ||
Range on Protein: 1270-1498
Range on HMM: 3-237/237.0
NIEKNRYGNINSFDETRVVLTKiPGiEGSDYINANYIDGY-GSRDTYIACQGPLAETSPDFWRMIWEQKTSCIVMLTNCVEKGRPKCHQYWPQTGS-TTF
| |||||||...| .|||| .| |||||||.|..|. |. .|||.|||| . |||.|.|..| | ||||| .|. . |||.|||.| ...
nkiknrygnivaydhsrvvlkg.ag.sgsdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpstdqpaay
GELTVTIIDQQVLAYYTIRTFKINNKDD--ESFEVKQFHYTAWPDFGVPDHPNPIISFIRR-VNNSTH---TGPLVVHCSAGVGRSGTFIAIQSMMLMME
| |||.. .. .. ||.|.. . .. | ..|...|.||| |||.. .. | .. .|.| | .|| ..||||||||.| |. |..|. .
gvltvslkkkeefsdytvrslllskrltlkevrlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlrqak
TEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVE
. ||..|.| . | |..||. ||.|.|....|
ekkvvdiynyvysieedrpyiiqtkdqyvfihqtile
|
|||||||||
subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 1543-1808 | 7.8e-65 | 213.6 | In-house | 24-289 (290) | alignment | ||
Range on Protein: 1543-1808
Range on HMM: 24-289/290.0
KQFEKLNSidVAIPSQYISASLPVNRAKNRYPDILPYESYRVRLLMLPGVSG--SDYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVM
.||..|.| . . . . . |. .||. .|..|. .|. | ..| .||||.|..|| .|.|.||||.|||. |||..||...|..|||
nqfkmlds..gesehtvtvgltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgykekkqyiatqgpvsntlvdFWkliwqekvtiivm
LCGLVEDGKDQSVQYWPKDQLTQYGDMFIETISETDTGFYVIREITITHTKQGNEVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAHHLFGGGPVVV
|. .|.||.. ||||. . ..|| . |. ..|. . |..|.. ......... ....|.. | | .. . . . . .| ..| .. | ...||
ltniieegkvkCqqYWpdsdtkaygefsikllneetlneyierklevknknsagakqsvtqyqitnwdstgkvtnpqtillvieemyktqrkrgntsivv
HDSSSVGRSGTFCIINIVIERLKVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYLESFDKY
| | .||||..|| ... |.. | || ||.| .. .| ..|| | .|... .| ...||.||..|
HCSdtvgrsavfcaaattinkcktegvidvfqvlksqRiqkpgsvqtvqqyqgifqivltyldsfety
|
|||||||||
subfamily_PTPN9_pd | Subfamily PTPN9 | 1543-1803 | 3e-64 | 211.9 | In-house | 20-291 (297) | alignment | ||
Range on Protein: 1543-1803
Range on HMM: 20-291/297.0
KQFEKLNSIDVAipSQYISASLPVNRAKNRYPDILPYESYRVRLLMLPGVSGSDYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLC
|..... . |. .. . |..| |||| |.| |.. || | ... . ||||||..|||| . . || ||||| .||.|||||.||..| |||
keyaeirnepve..GtflasklranleknrytdvlcydetrvvlakvdedeasdyinanfvdGykqkkafiatqGplkktvsdfWrmvWeqevlvivmtt
GLVEDGKDQSVQYWP--KDQLTQYGDMFIETISETDTGFYVIREITITHTKQgNEVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAHH---------
.|| |. . |||| ... ...||. ..... . |..| ..|...|. .| |.. | .. | . .| .. .|.|.. |...
rvvergrlkcgqyWpleeessaefgdlsvsnveveeeedykvrvleiknvkt.eesrkvthfqflsWPdyGvPssaaslldvlekvrekqalavkelgde
---LFGGGPVVVHDSSSVGRSGTFCIINIVIERLKVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYLE
| |.||| |. .||.|||. ..| ..||. .|..|.. |.. || . . .|..|||....||
wkghpsgPPivvhcsaGiGrtGtfitldiclsrleevgtvdvvetvkllrtqrafsiqtpeqyefcylavleyal
|
|||||||||
subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 1268-1501 | 3.6e-64 | 211.3 | In-house | 18-265 (270) | alignment | ||
Range on Protein: 1268-1501
Range on HMM: 18-265/270.0
TCNIEKNRYGNINSFDETRVVLTKIPGIEGSDYINANYIDGYGS-RDTYIACQGPLAETSPDFWRMIWEQKTSCIVMLTNCVEKGRPKCHQYWPQTGS--
. . . ||| .| .|||.| .. . . ||||||. |. . . .||| .|||. | .|||||||.|...|||.|. .|||| || .|||.
argkklnRyadiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkek
--TTFGELTVTIIDQQVLAYYTIRTFKINnKDDESFEVKQFHYTAWPDFGVPDHPN------PIISFIRRV---NNSTHT-GPLVVHCSAGVGRSGTFIA
...|...|. . .. | .. ... .. |. .. |.|..||| ||| ... ... .| | ..... .||.|||||||||.||.||
vkledgkikvlalseekeegyiltrlrle.ekgeerrlvHfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcsaGvgRtGtlia
IQSMMLMMETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELIK
. .. ..|...|||| . . ..|..| .||. || |.. ..|| ..
lDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyeflykavveyae
|
|||||||||
subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 1263-1497 | 2e-63 | 208.7 | In-house | 1-238 (239) | alignment | ||
Range on Protein: 1263-1497
Range on HMM: 1-238/239.0
EASQQTCNIEKNRYGNINSFDETRVVLTKIPGIEGSDYINANYIDGY-GSRDTYIACQGPLAETSPDFWRMIWEQKTSCIVMLTNCVEKGRPKCHQYWPQ
||... | |||| || ..| .|||| |. ||||||.|. | || .||| || .. .| |||||.|... ||||| .| . |||||||.
eaakkrvnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpd
TGStTFGELTVTIIDQQVLAYYTIRTFKINNK-DDESFEVKQFHYTAWPDFGVPDHPNPIISFIRRVNNSTHTG--PLVVHCSAGVGRSGTFIAIQSMML
. | . .| ||. .|.| | |||| ... . | | |.|.| ||| |||.. .. . |.. . . | | |.||||||||.|.|. |..|.
sts.kycnlrvtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlr
MMETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLV
. . ||.||.| .| | .|||| ||.|.| ...
qakkqktvdifnyvkairedrphmvqtseqyvfihlavl
|
|||||||||
subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 1265-1498 | 4.5e-63 | 207.6 | In-house | 2-238 (239) | alignment | ||
Range on Protein: 1265-1498
Range on HMM: 2-238/239.0
SQQTCNIEKNRYGNINSFDETRVVLTKIPGIEGSDYINANYIDGY-GSRDTYIACQGPLAETSPDFWRMIWEQKTSCIVMLTNCVEKGRPKCHQYWPQTG
... | |||| || ..| .|||| |. ||||||.|. | || .||| || .. .| |||||.|... ||||| .| . |||||||..
akkrvnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdst
StTFGELTVTIIDQQVLAYYTIRTFKINNK-DDESFEVKQFHYTAWPDFGVPDHPNPIISFIRRVNNSTHTG--PLVVHCSAGVGRSGTFIAIQSMMLMM
| . .| ||. .|.| | |||| ... . | | |.|.| ||| |||.. .. . |.. . . | | |.||||||||.|.|. |..|.
s.kycnlrvtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlrqa
ETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVE
. . ||.||.| .| | .|||| ||.|.| ...|
kkqktvdifnyvkairedrphmvqtseqyvfihlavle
|
|||||||||
subfamily_CG7180_pd | Subfamily CG7180 | 1567-1802 | 9.7e-63 | 206.5 | In-house | 42-290 (296) | alignment | ||
Range on Protein: 1567-1802
Range on HMM: 42-290/296.0
NRAKNRYPDILPYESYRVRLLMLPGVSGSDYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCGLVEDGKdQSVQYWPKDQLTQYGD
|| |||.....||. || | | | . ||||||.|||..|. ...|.|..| .|||.|||..... .||.|.|. . | . .|||... .|||.
nreknrdvkvvPyDynRvvLekldGeeksdYinavyvdsflkkkeyivteapkketvdefWrlvydeeisavvvLtktfdfak.mypsywpnkskeqyge
MFIETISETDTGFYVIREITITHT---------KQGNEVRNIKQFHYTDWSE-NKTPPTTGALMDMIVLVQKAHHLF----GGGPVVVHDSSSVGRSGTF
.|.|...| .||.. .|.. . |.| .|.|..| | .| | | ||.... |.. . |||||. | ..||| .
ifveiveekqyanlkirtfkltkkivalteqekqvkaetRivklfqlteWeledkvPlstnalielrrrvrlwrekvdedpeegPvvvvssdGasRsGvy
CIINIVIERLKVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYL
. |.. .| .. |. .|.| . |||. |..| | ...|..|... |..
laidanlelvekeeevdvFeavktlrrsRpqLvenveeYkyiYdvlleav
|
|||||||||
subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 1259-1501 | 5.8e-62 | 204.1 | In-house | 25-278 (287) | alignment | ||
Range on Protein: 1259-1501
Range on HMM: 25-278/287.0
SL--PHEASQQTCNIEKNRYGNINSFDETRVVLTKIPGiEGSDYINANYIDGYGSRDTYIACQGPLAETSPDFWRMIWEQKTSCIVMLTNCVEKGRPKCH
| |.... ...||||... .|.|||.|.. . |||||||||. .| ...||.|||.| | ||||...|.... ....| ||..| ||.
sstatfkaaeelaavkknryadvlPiddtrvllsaege.lGsdyinanyvasytddeafiaaqgPiaatvrdfwravletrsasvitmtreveearlkcy
QYWPQTGS-TTFGELTVTIIDQQVLA-YYTIRTFKINNKDDES-FEVKQFHYTAWPDFGVPDHPNPIISFIRRV-------NNSTHTGPLVVHCSAGVGR
.|||. | .|...|.... |..|.... . . . |||... .||| ... .| |. | ... .||||||...|.||
kywPerevPmrvGGysvvlldydikePeygvralrlidletrearvvkqldllswPdkvlaPtavglirfvldvkqhielardasevGPlvvhddvGiGr
SGTFIAIQSMMLMMETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELIK
||...|. .. ..| |.||| . |. .| .|. .||. |. .. ..|| |
sGillatlvlvsrledlGrvdvaavvirlreyraalvqavvqlrllyealvtyyk
|
|||||||||
subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 1566-1802 | 1.7e-61 | 202.9 | In-house | 48-279 (315) | alignment | ||
Range on Protein: 1566-1802
Range on HMM: 48-279/315.0
VNRAKNRYPDILPYESYRVRLLMLPGVSGSDYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCGLVEDGKDQSVQYWPKDQLTqYG
|. |||| .|..|. ||.| .| ..|||.||...||| . ...| .|||. ..|.||||...|. .. |||| .|||. | .. .||| .... ||
enkqknryiniiaydksrvqlpllendphsdyvnanfidGynkkrryiaaqgpnvasvkdfwrlvfeedigkivmltnlvegekrkaekywpdkkvi.yG
DMFIETISETDTGFYVIREItitHTKQGNEVRNIKQFHYTDWSENKTPPTTGALMDMIVLVqKAHHLFGGGPVVVHDSSSVGRSGTFCIINIVIERLKVE
. . .|| | .| . . |...|.. |.||| | . . | | .||..| | | || |..||| |. |||.|||. .. |......|
kitvtrkseevnteytvrtl...svvfgdnirevvqlhytswpdmgvpkytiplmnlirtv.kqhhtnsvgaivvhcsaGvGrtGtfitldavldqaeae
GMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYL
.||.. |. .|.. ..|. .|..| |....| .
naidvynfitgvrqnrikmvqvaeqyqfiydalletf
|
|||||||||
subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 1223-1525 | 6.5e-61 | 200.9 | In-house | 1-261 (392) | alignment | ||
Range on Protein: 1223-1525
Range on HMM: 1-261/392.0
RQSISVSMFPDYVKRLHanTDHLFSEEYELITiKSPSLPHEASQQTCNIEKNRYGNINSFDETRVVLTKIPGIEGSDYINANYIDGYGSRDTYIACQGPL
|| | |. || .|.. . ||.||. . . |. ..|. |..||||.|| .|..||.| | | |||.|| ||... . .|||.|||
rqpipvaqfpafveknr..hsalffeefhdlp.gpdiypqtvaqkeinlkknryknilpydsarvkleviddipdsdylnasyipsfdnekayiasqgpn
AETSPDFWRMIWEQKTSCIVMLTNCVEKGrpkchqywpqtgsttfgeltvtiidqqvlayytirtfkinnKDDESFEVKQFHYTAWPDFGVPDHPNPIIS
| . |||||....... |.|.|. | | |. | |||.| ||| .|| | . ..
aaslddfwrmvfqenvttiamvtklkegd.........................................kgddartvaqfhftewPdkdvpkhtssllk
FIRRVN--NSTHTGPLVVHCSAGVGRSGTFIAIQSMMLMMETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELIKVGNSEQTVQNFPKEAKILL
||. |. .| ||..||||||||.| |.|.|.. .. ||||||| ..|.|| |||||. || |.. ...| . |. | | ..|
fikevkadfGqythpliihcsagvgrtgvvisidsvvahakktrmvdvfnfvtnirrkrpymvqtkeqyafiygavledllwrntlipvvhftdhlqdls
TTQED
|. .
tssdG
|
|||||||||
subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 1557-1803 | 5.2e-59 | 194.6 | In-house | 34-278 (315) | alignment | ||
Range on Protein: 1557-1803
Range on HMM: 34-278/315.0
SQYISASLPVNRAKNRYPDILPYESYRVRLLMLPGVSGSDYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCGLVEDGKDQSVQYW
.. .| ..| |||| .|||..| ||.| .. ||||||||. .. . .| .|||| .|||||||.....|..|||. . |. | . |||
yrqrvaretinfkknryknilPldsarvkleviddsPdsdyinasyiksvdddkayiasqgPlkasvddfwrmvlqekvttivmvtkkqegdkikcrqyw
PK--DQLTQYGDMFIETISETDTGFYVIREItitHTKQGNEVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAhHLFGGGPVVVHDSSSVGRSGTFCI
|. .....| . .|..| .. |.|.. |....| |.. ||..|.| .. .. |..|. .| |. . ...|| |. |||.| ..
PdrkadsvefGsikvellsleadtdgvarkl...vtrkseesrtvtqfqftewPdkGvdkqtssllklikevkad.ngkkefsllvhcsaGvGrtGvvis
INIVIERLKVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYLE
|. |....| . ..|.| ... ||.| | .| ... | |... |.|
idevvaqikrtrsvdvfnfvknlrakrpylvqteeeyafiydavledll
|
|||||||||
subfamily_CG7180_pd | Subfamily CG7180 | 1266-1500 | 5.4e-59 | 194.3 | In-house | 38-290 (296) | alignment | ||
Range on Protein: 1266-1500
Range on HMM: 38-290/296.0
QQTCNIEKNRYGNINSFDETRVVLTKIPGIEGSDYINANYIDGYGSRDTYIACQGPLAETSPDFWRMIWEQKTSCIVMLTNCVEKGRpKCHQYWPQTGST
.. |.||||. .. .| .||||.|. | | |||||| |.|.. || ..| || .|||.......|..|.||. . . ....|||... .
lrkenreknrdvkvvPyDynRvvLekldGeeksdYinavyvdsflkkkeyivteapkketvdefWrlvydeeisavvvLtktfdfak.mypsywpnkske
TFGELTVTIIDQQVLAYYTIRTFKINNK--------DDES---FEVKQFHYTAWPD-FGVPDHPNPIISFIRRVNN-------STHTGPLVVHCSAGVGR
.||. | |. .. .| .|||||.. | ... ||.|..| |. || | .| ..|||. ..||.||..| |..|
qygeifveiveekqyanlkirtfkltkkivalteqekqvkaetRivklfqlteWeledkvPlstnalielrrrvrlwrekvdedpeegPvvvvssdGasR
SGTFIAIQSMMLMMETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELI
|| ..||. . ..| |..||||..| .|..|. .|.. .|... | | | .
sGvylaidanlelvekeeevdvFeavktlrrsRpqLvenveeYkyiYdvlleav
|
|||||||||
subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 1543-1804 | 7.7e-59 | 194.1 | In-house | 19-278 (281) | alignment | ||
Range on Protein: 1543-1804
Range on HMM: 19-278/281.0
KQFEKLNSIDVAIPSQyiSASLPVNRAKNRYPDILPYESYRVRLLMLPGVSGSDYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLC
...|||..|.| ... .. . |. |||| .| |. ||.. . .|||||..|.|| ...| ||||. .....||.|.||..||||||.
eeyeklaaigvdntat..askadenvlknrYsnivaYDatrvkvtpneenkntDYinanfvpgykgekeyiatqgPvPaslvafWqmvweqkvsaivmvt
GLVEDGKDQSVQYWPKDQ-LTQYGDMFIETISETDTGFYVIREITIthTKQGNEVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAHHLFGGGPVVVH
.| || . .||| |. ..|||. .....|... |. |.... .....| |...|..|| | .. | || .|.. |.|... |.|.|
reieagklkChrYWPddnselkygdvtvkstaeeekatyierkfkl..eresgetreveqlaytaWPdhGvPattkellefrkevlkltekktkaplvih
DSSSVGRSGTFCIINIVIERLKVE-GMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYLES
|. |||.||. .. ...... | ..|. ... ||.. .| |..| |......|.
CsaGvGrtGtyialDrlvkaveaeleeldvkavvaelrkernlmvqtvvqyefvykavldaldk
|
|||||||||
subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 1563-1803 | 1.7e-58 | 193.0 | In-house | 39-277 (515) | alignment | ||
Range on Protein: 1563-1803
Range on HMM: 39-277/515.0
SLPVNRAKNRYPDILPYESYRVRLLMLPGVSGSDYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCGLVEDGKDQSVQYWPK--DQ
.| |||| .||||.| ||.| .. |||.||||. .. . .| .|||. .||||||......|..|.|. | |. | . .|||. .
qeeinfkknryknilPydsvrvklevindnPhsdyfnasyipsfdndkayiasqgPnkasvddfWrlvlqenvttiamvtklkegdkikcgkyWPdkpgd
LTQYGDMFIETISETDTGFYVIREITIThtkQGNEVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAHHLFGgGPVVVHDSSSVGRSGTFCIINIVIE
..| . .|..| . ..|..|.. .|...| . |||.|.| .. .|. | .|. .| |. | . |...| |. ||| | .. |. |.
svkfGsikvelvsleactggikrkltvl...kgddsrtvtqfhfteWPdkGvpkhtssllklikevkadhgqyt.hpliihcsaGvGrtGvvisidsvva
RLKVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYLE
. | |.|.| ... .|.| | .| .|. | |... |.|
hakttrmvdvfnfvtnirqkrpylvqtqeqyafiygavledll
|
|||||||||
subfamily_PTPN23_pd | Subfamily PTPN23 | 1268-1500 | 2.1e-58 | 192.4 | In-house | 41-280 (288) | alignment | ||
Range on Protein: 1268-1500
Range on HMM: 41-280/288.0
TCNIEKNRYGNINSFDETRVVLTkipgIEGSDYINANYIDGYGSR-DTYIACQGPLAETSPDFWRMIWEQKTSCIVMLTNCVEKGRPKCHQYWPQTG--S
.. ||||. .| .|..||.| . ||||| .. . . ..|| |.||..|. |||.|..|||.| ||||.. |.|.||...|||. .
klyseknrsrdilPyDhnRvklr....gskDDYinAsfvkdlspgcPdfiatqaPlqstlnDFWlmvyeqkssviVmllskeelgkpkvdrYwPedkget
TTFGELTVTIIDQQVLAYYTIRTFKINNKD-DESFEVKQFHYTAWPDFGVPDHPNPIISFIRRVNN-------STHTgPLVVHCSAGVGRSGTFIAIQSM
..||.|.||. ... . .. |..|.. .| |. .|. ..|.||..|||. |. .. |. |.. ..| ||||||||||||.|.| . .
vkfgdlsvtlksvretethvervlkletldadavksvshlqltsWpelGvPasPetllqfldevesayeavqrkskt.PlvvhCsaGvgRtgvfalvyaa
MLM-METEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELI
. . .| .|. . | .|..| .|||...|. |. . .| .
vrelekgnglldiiqvvsrlreqRrfmvqekeqlkfsyeavleaa
|
|||||||||
subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 1240-1506 | 6e-58 | 191.0 | In-house | 5-272 (283) | alignment | ||
Range on Protein: 1240-1506
Range on HMM: 5-272/283.0
ANTDHLFSEEYELITIksPSLPHEASQQTCNIEKNRYGNINSFDETRVVLTKIPGiegsDYINANYID---GYGSRDTYIACQGPLAETSPDFWRMIWEQ
.|. .|| | .. ... |.|. . . | .|||. .| . | || | . ||||| .| | ||..|.|| .| |||.|....
vnnnklfrevlkrlsv..pdldadiasadenkrknrnqeivpadqwrvelksesr....dyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfde
KTSCIVMLTNCVEKGRPKCHQYWPQTGSTTFGELTVTIIDQQVLAYYTIRTFKINNK--DDESFEVKQFHYTAWPDFGVPDHPNPIISF--IRRVNNSTH
| ..|||||. | | || ||||. || .||.|||. .. ..|. . .... ... . . . | ..| | .. | .. . .
kitaivmltklqedlrikCsqyWPkrGsedyGeftvtlrkettsnsfiikelllrvnssakstlllahyqvidWleygeqaiinslvkfnkvislqtesk
TGPLVVHCSAGVGRSGTFIAIQSMMLMMETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELIKVGNSE
||.|||||.|.||...|||. . . . || ||||. | || .| .||| ||..||. .| .|...
kgPivvhCstgiGrtavfiaasasvkdaltesvvdvfavvkimreqrmmavqtldqyklvhelvleqalcgdtq
|
|||||||||
subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 1562-1806 | 1.5e-57 | 190.0 | In-house | 46-288 (297) | alignment | ||
Range on Protein: 1562-1806
Range on HMM: 46-288/297.0
ASLPVNRAKNRYPDILPYESYRVRLLMLPGVSGSDYINASYVDGYLRcnQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCGLVEDGKdQSVQYWPKDQL
| || |.|| .||||.| ||.| .. |||.|||.| |. ..| || | .||.|||.|.....||.|||| . | | . .||...
aekkvnfeksRYkniLPydssRvkLaivnddpdsDyvnasfvkgnkh..rlittqmPmkatvadfWamvldeqvstivmlnddnerdk.kcaryWsdkgv
TQYGDMFIETISETDTGFYVIREITITHTKQgNEVRNIKQFHYTDWSENKTPP--TTGALMDMIVLVQKAHHLFGGGPVVVHDSSSVGRSGTFCIINIVI
|..||. ... | .. .. ||...|. | | .||.....| ... . .. .|...| |.| . ||..|| .. ||| | .. |. |.
ttfGdvsvvllsvsereGfikrelevtkgka.karrvvkqyqfveWPdkaverkdsassllklisevrkdfsqnaegPllvhclaGvGrtgvlltidsvv
ERLKVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYLESFD
. | | .||| ... ||.. | .| .|.|| |....|.| | |
aeakrekevdifglvkklrqerpylvqtkeqykfvyvavleallsed
|
|||||||||
0051429 | (Phosphotyrosine protein) phosphatases II | 1295-1501 | 3.3e-57 | 189.5 | In-house | 1-226 (272) | alignment | ||
Range on Protein: 1295-1501
Range on HMM: 1-226/272.0
IEGSDYINANYIDGYGS---RDTYIACQGPLAETSPDFWRMiWEQKTSCIVMLTNCVEKGRPKCHQYWP------------QTGSTTFGELTVTIIDQQV
.. |.||||....|||. ........||| | ||||. .|.. ..||.|....|.|| ||..||| . . ..| |.||.. ..
lplsgyiNardvggygrvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseel
LAYYTIRTFKINNK--DDESFEVKQFHYTAWPDFGVPDHPnpIISFIRRVNNsthTGPLVVHCSAGVGRSGTFIAIQSMMLMMETEGKVD--------VF
| .|..|.. . .. .|..|| ..|||.|||.|||... ...... ... ||..||||||..|.||..|. ..| .. | || ..
lldyilrellltlllsagearevmhlhytdwpdhgvpqea..llellellld...ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlyle
NFVLDMRHKRNYMVQTEAQYMFVHDSLVELIK
..| .| .| ..||||.||.|... |.||..
eaveelraqrpgavqteeqylflyeallellr
|
|||||||||
subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 1547-1804 | 9.3e-57 | 187.2 | In-house | 6-270 (274) | alignment | ||
Range on Protein: 1547-1804
Range on HMM: 6-270/274.0
KLNSIDVAIPSQY--ISASLPVNRAKNRYPDILPYESYRVRLLMLPGVSG-SDYINASYVDGYLR-CNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLC
.|.. . .|. . ... . |||| .||| | || | . . |.|||| |. || . . .. |||||.|||.||||||....|. ||||
dlekeflelPlnfdqeeldvfgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmlt
GLVEDGKDQSVQYWPKDQLT----QYGDMFIETISETDTGFYVIREITITHTKQgneVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAHHLFGG--G
| | ... ..|.|... . .|||. |.. . ... | .|.... .... |..| . |||| ..|.| . .|.|.. |..... .
klkeaneqkCavyfPdaedyeiserygdveikvekiverndysvrklvlkyler...ersvkhywytdWPdhksPddantlldlvleveesreeenakla
PVVVHDSSSVGRSGTFCIINIVIERLKVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYLES
||||| |. .|| | | |.| . .|. |...|.. .. || . |.| . .|... ......||.
pvvvhCsaGiGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralclylkr
|
|||||||||
subfamily_PTPRN_pd | Subfamily PTPRN | 1234-1498 | 1.1e-56 | 186.7 | In-house | 20-290 (297) | alignment | ||
Range on Protein: 1234-1498
Range on HMM: 20-290/297.0
YVKRLHANTDHLFSEEYELITIKSPSLPHEASQQTCNIEKNRYGNINSFDETRVVLTKIPGIEGSDYINANYIDGYGSR-DTYIACQGPLAETSPDFWRM
|.. | |.| | | . .. .|.... |..|||. .. ..|..|| |.. | |||||| | | .|||.|||||.| |||.|
yledhlknkdrlekewealcayeaepstkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplastvadfwqm
IWEQKTSCIVMLTNCVEKGRPKCHQYWPQTGSTTFGELTVTIIDQQVLA-YYTIRTFKINN-KDDESFEVKQFHYTAWPDFGVPDHPNPIISFIRRVNNS
.||| . ||.||. |.| .|..|||..|| ... | .. . . . | .|.| . | . .|. | |||. .||. ||| ..... | |.|| |
vweqGvvvivnltrleeegvkqckrywpdeGsevyhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnks
T--HTGPLVVHCSAGVGRSGTFIAIQSMML-MMETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVE
. |.|||||.|.||.|..|.|. .. .. ..|. . .| .|. .|.|..|. |. ...|
yrGrscpivvhcsdGaGrtGvyilidlvlnrllkGvkeidiaatlehlrdqrpglvktkdqfefaltavae
|
|||||||||
subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 1241-1504 | 1.3e-55 | 183.3 | In-house | 13-297 (301) | alignment | ||
Range on Protein: 1241-1504
Range on HMM: 13-297/301.0
NTDHlFSEEYELITIKSPsLPHEASQQTCNIEKNRYGNINSFDETRVVLTKIPG--IEGSDYINANYIDGYGSRDTYIACQGPLAETSPDFWRMIWEQKT
.... |.|.|. .. ... . . . . | . ||. ||. .|. |..|.. | . .||||.||||| .. .|| |||. .| ||||.||..|.
hsnk.feeqykelkeged.ksctvglseenkalnrfknitvyddnriilkpkpnldlcqreyinasyidgysekkkfiaaqgpmkktlvdfWrliwqekp
SCIVMLTNCVEKGRPKCHQYWPQ--TGSTTFGELTVTIIDQQVLAYYTIRTFKIN----------------NKDDESFEVKQFHYTAWPDFGVPDHPNPI
. |||.|| |. . ||.||||. . |..||..|||....||. ..|| .... ..| .| .| |.. | ||. || |. .
vsivmvtnlkegtkskceqywpnseaeseefgpftvtlvneqvyPdfvirqlnvkiqdgsnngyierkfkvksdksswdvlqlqvtdWpqdGvvreprtv
ISFIRRV---NNSTHTGPLVVHCSAGVGRSGTFIAIQSMMLMMETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELIKVGN
. | | ... ||.|||||..|.|||...... . || ||||. . .|... .|.| ||....| . . ... .
LqviddvihrqqkigggpvvVHCSdtVsrsGvYcsvsiglEQckaegVVdvfqvtkavrrskpgaVtTLeqytsiydvidmylqlns
|
|||||||||
subfamily_PTPN14_pd | Subfamily PTPN14 | 1245-1501 | 3e-55 | 182.3 | In-house | 25-297 (300) | alignment | ||
Range on Protein: 1245-1501
Range on HMM: 25-297/300.0
LFsEEYELITIKSPSLPHEASQQTCNIEKNRYGNINSFDETRVVLTKIPGIeGSDYINANYIDGY--GSRDTYIACQGPLAETSPDFWRMIWEQKTSCIV
.| ||| |. |. .... | ||||. .. ....|| |. ..|||| | |.. .||..|||| | |||.|.|||... ||
vf.teyeripkkredallstaklpenaeknrfkdvlPyednrvelsptken.stgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqliv
MLTNCVEKGRPKCHQYWPQTG----STTFGELTVTIIDQQVLAYYTIRTFKINN-KDDESFEVKQFHYTAWPDFGVPDHPNPIISFIRRVN------NST
|||. |.|. |...|.|... . .||. || .. .. ...|.. | .| . || ||| |||. ... .|....|. ||.
mlteeeedgkeksfkyfPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnse
H-----TGPLVVHCSAGVGRSGTFIAIQSMMLMMETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELIK
|..|||||||||.| | . .. .|.. ..|. . . .|..| ..||| ||| ||.. |.. .|
veskeskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLreqrmllvqtlaqYkfvYkvlikylk
|
|||||||||
subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 1564-1810 | 1e-54 | 180.3 | In-house | 37-301 (301) | alignment | ||
Range on Protein: 1564-1810
Range on HMM: 37-301/301.0
LPVNRAKNRYPDILPYESYRVRLLMLPG--VSGSDYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCGLVEDGKDQSVQYWPKDQL
|.| ||. .| .|. |. | | .. .||||||.||| . ..||..|||. .|. ||||.||......|||...| |. |... ||||. .
seenkalnrfknitvyddnriilkpkpnldlcqreyinasyidgysekkkfiaaqgpmkktlvdfWrliwqekpvsivmvtnlkegtkskceqywpnsea
TQ--YGDMFIETISETDTGFYVIREITITHTKQGN--------------EVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAHHLFGGGPVVVHDSSS
.. .| . .. ..|. .|||..... .. | . ... |.. ||| .. . . | | .. . |||||||| | .
eseefgpftvtlvneqvyPdfvirqlnvkiqdgsnngyierkfkvksdksswdvlqlqvtdWpqdGvvreprtvLqviddvihrqqkigggpvvVHCSdt
VGRSGTFCIINIVIERLKVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYLESFDKYAN
|.|||..| ..| .| | || .|.| ..|.||..|| | .|. . |. | .||. . |||
VsrsGvYcsvsiglEQckaegVVdvfqvtkavrrskpgaVtTLeqytsiydvidmylqlnstyan
|
|||||||||
subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 1559-1804 | 1.8e-54 | 180.0 | In-house | 40-290 (325) | alignment | ||
Range on Protein: 1559-1804
Range on HMM: 40-290/325.0
YISASLPVNRAKNRYPDILPYESYRVRLLMLPGVSGSDYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRvSAIVMLCGLVEDGKDQSVQYWPK
. | .| |.||||........ || | . . ||||||||. . . . |. .| ||..|..|.||.. . | ...|.. .. |||. .||||
kkvamkpenkaknrfknvvaldksrvvletkkddpssdyinasylrddkkkdvflaaqaPltatindlWrlvldWr.csvvvvlneldlgkdrcavywpk
D--QLTQYGDMFIETISETDTGFYVIREITITHTKQGnEVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAHHLF-----GGGPVVVHDSSSVGRSGT
. . ..| . .. .. . || | . . .|.| | | .|||.. | . .. .|. .. ||.. . . .|..|| |. |||.|.
emgksktfGglevklrtieeisdyvhrvldvkqvkkG.etrsvkqfqlqswddmGvqkrpatlisilqlvkavservtantkastpilvhcsaGvGrtGv
FCIINIVIERLKVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYLES
| . ..... | .||| .. ||.. | .| ||. ..|...||.. |
fislysalakvieesrvdifgfvkklrkdrpsmvetvdqyiliyealveayms
|
|||||||||
subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 1567-1804 | 2.9e-54 | 178.9 | In-house | 20-266 (270) | alignment | ||
Range on Protein: 1567-1804
Range on HMM: 20-266/270.0
NRAKNRYPDILPYESYRVRLLMLPGVSGSDYINASYVDGYLR-CNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCGLVEDGKDQSVQYWPKDQL--TQ
... ||| |||| |||| | | . |||| || |. ...| ..||| .|. .|||||||..|.||||. ||.|.|... .|||... ..
gkklnRyadiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkekvk
YGDMFIETIS--ETDTGFYVIREITIThtKQGNEVRNIkQFHYTDWSENKTPPTTG------ALMDMIVLVQKAHHLF-GGGPVVVHDSSSVGRSGTFCI
. |..|.... |. . .|........ ..|.| | . |.|..| .. |.... |. |. |.. .. . ..|..||.| |||.||. .
ledgkikvlalseekeegyiltrlrle..ekgeerrlv.HfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcsaGvgRtGtlia
INIVIERLKVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYLES
..|... |. .. .|. |..||.. . .| .|..| |...||| |
lDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyeflykavveyaer
|
|||||||||
subfamily_PTPN3_pd | Subfamily PTPN3 | 1559-1801 | 1.1e-53 | 177.0 | In-house | 33-274 (280) | alignment | ||
Range on Protein: 1559-1801
Range on HMM: 33-274/280.0
YISASLPVNRAKNRYPDILPYESYRVRLLMlpgvSGSDYINASYVD----GYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCGLVEDGKDQSVQ
| .| | .|||| |||||.. ||.| | .|||||.||. . |..| |||||..|. |||.|.||...| |||| |||.|. . |
isaarkpenlsknryrdilpydatrvklke....setdyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqksslivmlttlverGrvkChq
YWPKD-QLTQYGDMFIETISETDTGFYVIREITITHTKQgNEVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAHHLfGGGPVVVHDSSSVGRSGTFC
|||. . ..||.. .. .| | ||.||........ .| |.| |. |..|.... | . ..... |.|... ||||| |. .||.| .
yWPetedeleygefsvkcekedetksyvlrelvlkdket.keerkilqlqylaWpdhgvPddsadflefvervrklrsg.keePvvvhCsaGigrtGvli
IINIVIERLKVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEY
.... . . . . . .. .| . .| . .|.|| ..|..
lletalalieaaepvypldivrtmrdqramlvqtasqykfvCeailkv
|
|||||||||
0041856 | (Phosphotyrosine protein) phosphatases II | 1270-1504 | 2.7e-53 | 175.6 | In-house | 1-175 (182) | alignment | ||
Range on Protein: 1270-1504
Range on HMM: 1-175/182.0
NIEKNRYGNINSFDETRvvltkipgieGSDYINANYIDGYGSRDTYIACQGPLAETSPDFWRMIWEQKTSCIVMLTncvekgrpkCHQYWPqtgsttfge
|..|||| .| .| .| ..||||||...|. ...||.|||| .| .||.||..|.. ..||.|| ...|||
nldknrysdilpydhsr..........dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt.........eelywp.........
ltvtiidqqvlayytirtfkinnkDDESFEVKQFHYTAWPDFGVPDhPNPIISFIRRVNNstHTGPLVVHCSAGVGRSGTFIAIQSMMLMmetegKVDVF
... .. |..|. |||.|||| .. ...||..|.. . || .|||||||||.||..|. |. . .|...
........................ellerlgiqylylpwpDhgvpd.ldelldfieevle..eggpvlVHCsaGvgRtgtlvaaylmkkl.....gvsle
NFVLDMRHKRNYMVQTEAQYMFVHDSLVELIKVGN
. | .| .|. ||.|. || |... | ||.....
eavklvrsrRpgmvitpnqyfflqlallellllkk
|
|||||||||
subfamily_PTPN23_pd | Subfamily PTPN23 | 1541-1804 | 3e-53 | 175.5 | In-house | 17-282 (288) | alignment | ||
Range on Protein: 1541-1804
Range on HMM: 17-282/288.0
LPKQFEKLNSIDVAIPSQYISASLPVNRAKNRYPDILPYESYRVRLLmlpgVSGSDYINASYVDGYL-RCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIV
| |.|..|.. . . . | .. |||. |||||.. || | | ||||||.| . | .||.||.|| .|. |||.|..| ..| ||
ldkkfkeleqkqdkearkrsiaiaklyseknrsrdilPyDhnRvklr....gskDDYinAsfvkdlspgcPdfiatqaPlqstlnDFWlmvyeqkssviV
MLCGLVEDGKDQSVQYWPK--DQLTQYGDMFIETISETDTGFYVIREITITHTKQgNEVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAHHLF---G
|| | || . .|||. .. ...||. . |...|. .| |...... .. ..|.... ..| |.| | . . |.... |..|..
mllskeelgkpkvdrYwPedkgetvkfgdlsvtlksvretethvervlkletlda.davksvshlqltsWpelGvPasPetllqfldevesayeavqrks
GGPVVVHDSSSVGRSGTFCIINIVIERLKV-EGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYLES
|.||| |. |||.|.|... ... |.. .|..|| .. ||.. | . .|.||.|. ..|. .
ktPlvvhCsaGvgRtgvfalvyaavrelekgnglldiiqvvsrlreqRrfmvqekeqlkfsyeavleaarr
|
|||||||||
subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 1545-1802 | 5.8e-53 | 174.9 | In-house | 26-279 (439) | alignment | ||
Range on Protein: 1545-1802
Range on HMM: 26-279/439.0
FEKLNSIDVAIPSQYISASLPVNRAKNRYPDILPYESYRVRLLMLPGVSGSDYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCGL
|||.||.. . |. ...|||| |. ... || | .||| | |||| |..|| . .| |||| .|.|||||...|.... ||||. |
fekinstspdyaciaslaaqeydqtknrykdvgafdhtrvtlqeipgvphshyinanyikGyyddklyiatqgpkkettddfwrlviekktvtivmltnl
VEDGKdqsvqYWPKDQLTQYGDMFIETISETDTGFYVIREITITHT-KQGNEVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAHHLFGGGPVVVHDS
|| | ||| |. . |||. . . . . |||| . . ... | . ||||. | ... | . ..|.. .. | |||||| |
vesyk.....ywpsdaevcygdiavrvdrnielpnyvirgfkvfnerdttekertvlqfhyiawpdknvpaqashvldflrainsandkeeygpvvvhcs
SSVGRSGTFCIINIVIERLKVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYL
. |||.|| ..| .|.||.| .|| .. ||... .| . |. | |....| .
agvGrtGtiialdialeqlklenkvdikgivkvlrkqrkqmvqalcqyvfiynavledi
|
|||||||||
subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 1243-1499 | 5.9e-53 | 174.9 | In-house | 15-276 (307) | alignment | ||
Range on Protein: 1243-1499
Range on HMM: 15-276/307.0
DHLFSEEYELITIKSPS-LPHEASQqtCNIEKNRYGNINSFDETRVVLtKIPGIeGSDYINANYIDGYGSRDTYIACQGPLAETSPDFWRMIWEQKTSCI
. . .|.. .. |.| .. || . .| .|||| ... | .|.|. |..|. |||| |||. .|..|||| .| .|| |. ..| ..
vqalvdefrvlakktpegvtveafs..antdknryqdvkcqdkgrivv.kfdgl.asdyihanylgiaikpkkficaqgplentqysfwamaiqekvesv
VMLTNCVEKGRPKCHQYWPQT--GSTTFGELTVTII----DQQVLA----YYTIRTFKINNkDDESFEVKQFHYTAWPDFGVPDHPNPIISFIRRVNNSt
.|| ...| .. ||.|||| .||| . || . || . . |.|.. ..| .... .. ||| |||. | .. |.
imlckvielakikceqywpleegqklvfgeapntisvanlgakklapdedlinvttlkvdw.aqksrtiqhlqwenwpdrgvpqinltainlleavryd.
hTGPLVVHCSAGVGRSGTFIAIQSMM-LMMETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVEL
| |.||||||||||||| .|| .. |.. . |. ..| ..| .|.| .||||||...| |.|
.tnpvvvhcsaGvGrsGtivaislvqdkmiaGinckdmkklveelrsqrhyaiqteaqylylhrvlley
|
|||||||||
subfamily_PTPN1_pd | Subfamily PTPN1 | 1561-1801 | 7.6e-53 | 174.1 | In-house | 26-270 (290) | alignment | ||
Range on Protein: 1561-1801
Range on HMM: 26-270/290.0
SASLPVNRAKNRYPDILPYESYRVRLLMlpgvSGSDYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCGLVEDGKDQSVQYWPKDQ
.| || ||..||| |. ||. |..| . |||||| |. ..|.|||||.|||| ||.|.||.. |.||| .|| .. . .||||...
eaklpenrnlnryrdvspydhsrikler....adndyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvvekeqikcaqywPqge
L-----TQYGDMFIETISETDTGFYVIREITITHTKqGNEVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAHHLFG-GGPVVVHDSSSVGRSGTFCI
. . .. ||| .. .|..| . .. | .| |.| .|||| |.. | . .|..... |... | ||.|.| |. .|||||||.
eekellledtklkvkliseerksyytvrllelenlk.tqetreilhfhyttwpdfgvpespaaflkflfkvresGslssdvGpavihcsaGiGrsGtfcl
INIVIERLKVEGM---IDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEY
.. .. ... .. .|| .. .||. |.. ||..| |..|.|
vdtclvliekkddlssvdikkvllelrkyrlGliqtadqlrfsylaileG
|
|||||||||
0036282 | (Phosphotyrosine protein) phosphatases II | 1297-1494 | 1.2e-51 | 170.1 | In-house | 1-164 (174) | alignment | ||
Range on Protein: 1297-1494
Range on HMM: 1-164/174.0
GSDYINANYIDGYGSRDTYIACQGPLAetspdFWRMIWEQKTSCIVMLTNCVEKGRPKCHQYWPQtgsttfgeltvtiidqqvlayytirtfkinNKDDE
|||||||...|.. . .||.||||| ||.|..|.. ...|||....|.|. ||..||| ...|.
gsdyinaspldlsyitprliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe..............................lredl
SFEVKQFHYTAWPDFGVPDHPNpIISFIRRVNNS---THTGPLVVHCSAGVGRSGTFIAIQSMMLMMEtEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVH
. .. |..|. |||.|||| . ...|...|.. . ||..|||||||||.||..|. |. ... |. ||....| .| .| .||||. ||.|..
erlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtpsQyrfly
D
.
y
|
|||||||||
subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 1543-1804 | 1.2e-51 | 170.2 | In-house | 14-279 (287) | alignment | ||
Range on Protein: 1543-1804
Range on HMM: 14-279/287.0
KQFEKLNSIDVAIPSQYISASLPVNRAKNRYPDILPYESYRVrLLMLPGVSGSDYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLC
|....| . . . .| . |||| |.||.. || || | ||||||| || .| . ..|| .|||.. || ||||...|.|.......
kevdalkedsesstatfkaaeelaavkknryadvlPiddtrv.llsaegelGsdyinanyvasytddeafiaaqgPiaatvrdfwravletrsasvitmt
GLVEDGKDQSVQYWPKDQL-TQYGDMFIETISETDT-GFYVIREITITHTkQGNEVRNIKQFHYTDWSENKTPPTTGALMDMIVLV----QKAHHLFGGG
||... . .|||. . . | . .. . | .| . . . ...| | .||... .| .. .||. .|. ... | . | . |
reveearlkcykywPerevPmrvGGysvvlldydikePeygvralrlidl.etrearvvkqldllswPdkvlaPtavglirfvldvkqhielardasevG
PVVVHDSSSVGRSGTFCIINIVIERLKVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYLES
|.||||. .||||.. . ....||. | .|. .. || . ..| |... |...| | ..
PlvvhddvGiGrsGillatlvlvsrledlGrvdvaavvirlreyraalvqavvqlrllyealvtyykt
|
|||||||||
subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 1225-1499 | 1.7e-51 | 169.6 | In-house | 8-282 (290) | alignment | ||
Range on Protein: 1225-1499
Range on HMM: 8-282/290.0
SISVSMFPDYVKRLHANTDHLFSEEY-ELITIKSPSLPHEASQQTCNI--EKNRYGNINSFDETRVVLTKipGIEGsDYINANYIDGygSRDTYIACQGP
|. . | . . . .. || | . |. . | . | .|||| .. | |||.| | .| ||. |||..| . ..| ||.
svqteafekfasdvvkknvdelakeyleklkpylpvqylerkifdkntefkknrykdvvcndktrvilkd..GydG.dyvhanyvkG..lkamfiltqGa
LAETSPDFWRMIWEQKTSCIVMLTNCVEKGRPKCHQYWPQTG--STTFGELTVTIIDQQV-LAYYTIRTFKINNKDD-ESFEVKQFHYTAWPDFGVPDHP
|..| |.|||. ..|.. |||| . .|.|..||.||.|.. ||||.||. .. | .|. . .||. . .| .. .||| |.
lkdtvidiwrmvlqekvaaivmlceliedGkakceqyypekeGevltfGeitvlcseeddkdaniikktlsvrdkdsGkehklkhlkikswpdksvalst
NPIISFIRRVNnsTHTGPLVVHCSAGVGRSGTFIAIQSMMLMMETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVEL
.. .| . . .||.|||||||.||.|||.||. . .. ..|. . | .|. | || . ||. . . |..|
lallrtlrilr..kasGpvvvhcsaGiGrtGtfvaievglqilldGkeldlldlvralrnsrlnsvqvdiqylalveilldl
|
|||||||||
subfamily_PTPN14_pd | Subfamily PTPN14 | 1556-1803 | 1.9e-51 | 169.9 | In-house | 38-297 (300) | alignment | ||
Range on Protein: 1556-1803
Range on HMM: 38-297/300.0
PSQYISASLPVNRAKNRYPDILPYESYRVRLLMLPGVsGSDYINASYVDGYLRCN--QFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCGLVEDGKDQSV
... .|.||.| |||..|.|||| ||.| ..||||| . . . ..|..|||| .|| |||.|.||. |. |||| ||||..|.
dallstaklpenaeknrfkdvlPyednrvelsptken.stgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivmlteeeedgkeksf
QYWPKD----QLTQYGDMFIETISETDTGFYVIREITITHTKQGnEVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQ----KAHHLF----GGGPVVVH
.|.||. . ..| . | .|.. .. . ... | . | |.. . ||||.... |. .. . || |... ||.||
kyfPkleskkktvefgkfkvttkfsedsdsvittglklkhlpsk.eertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseveskeskPPvlvh
DSSSVGRSGTFCIINIVIERLKVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYLE
| |||.| . ...|. |. . ||| ... ||.. .|.. |.|| |.....||.
CsaGvGrtGvlilsdlliatlehneeidikkvlarLreqrmllvqtlaqYkfvYkvlikylk
|
|||||||||
subfamily_PTPN13_pd | Subfamily PTPN13 | 1561-1804 | 2.4e-51 | 169.6 | In-house | 31-271 (273) | alignment | ||
Range on Protein: 1561-1804
Range on HMM: 31-271/273.0
SASLPVNRAKNRYPDILPYESYRVRLlmlpGVSGSdYINASYVDGYLRCNQ--FIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCGLVEDGKDQSVQYWPK
.. |..|||| ..|||. ||.| | .|. |||||.. . .. .|..|||| .||.|||.|.|| ... |.|. .|.|| . .|||.
vgkkkenkdknryrnvlPydetrvkl....gdegg.yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvkchrywPe
D---QLTQYGDMFIETISETDTGFYVIREITITHTkQGNEVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAHHlfGGGPVVVHDSSSVGRSGTFCII
.|. .. . .| . .. .|.|....... . .|.|.. ......| . ..| .. |. .. |.. .. ||.||| |. .|||||. |
sknkklkvsnrlevellkvqkldgfvvralavkds.esgesrevahlnfvkwPdhgvPssaaellqfvaevrrlqt..dagPivvhcsaGiGrsGtliti
NIVIERLKVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYLES
..|.. .. . .|. ... ||.. |.| ||. |.|..|.| |.|
dvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykailevlks
|
|||||||||
subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 1544-1800 | 5.2e-51 | 168.2 | In-house | 11-264 (283) | alignment | ||
Range on Protein: 1544-1800
Range on HMM: 11-264/283.0
QFEKLNSIDVAIPSQYIsASLPVNRAKNRYPDILPYESYRVRLLMLPGvsgsDYINASYVD---GYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVM
..|.|. . | . | || |. |||. .|.|.. .||.| .. |||||... | . ...|..|.|| .|| |||.|.......||||
frevlkrlsvpdldadi.asadenkrknrnqeivpadqwrvelksesr....dyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekitaivm
LCGLVEDGKDQSVQYWPKDQLTQYGDMFIETISETDTGFYVIREITITHTKQGNEVRNIKQFHYTDWSENKTPPTTGAL--MDMIVLVQKAHHlfgGGPV
| | || . . |||||. .||.. . || ..|.|... . .. . . . || | . .| .. .. |. .. ||.
ltklqedlrikCsqyWPkrGsedyGeftvtlrkettsnsfiikelllrvnssakstlllahyqvidWleygeqaiinslvkfnkvislqtesk...kgPi
VVHDSSSVGRSGTFCIINIVIERLKVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVE
||| |. .||...|. . .. .. | ..|.| ... .| . ...| . ||.|. .. ..|
vvhCstgiGrtavfiaasasvkdaltesvvdvfavvkimreqrmmavqtldqyklvhelvle
|
|||||||||
subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 1566-1800 | 7.7e-51 | 167.6 | In-house | 2-237 (237) | alignment | ||
Range on Protein: 1566-1800
Range on HMM: 2-237/237.0
VNRAKNRYPDILPYESYRVrLLMLPGvSGSDYINASYVDGYLR-CNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCGLVEDGKDQSVQYWPK-DQLTQ
|..|||| .| |. || .| .| ||||||||.|..|. ...| .|||| .. ||||.|.|. . | |||| ||.| . . .|||. || .
enkiknrygnivaydhsrv.vlkgag.sgsdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpstdqpaa
YGDMFIETISETDTGFYVIREITITHTKQGNEVRNIKQFHYTDWSENKTPPTTGALMDMI-VLVQKAHHLFGGGPVVVHDSSSVGRSGTFCIINIVIERL
|| . . . . | .| ..... . .||| |.|...| | .. | | ||. . ......|. || ..| |. |||.| | .|. .. .
ygvltvslkkkeefsdytvrslllskrltlkevrlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlrqa
KVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVE
| . ..||. .... .| |. ||. | .|||.|
kekkvvdiynyvysieedrpyiiqtkdqyvfihqtile
|
|||||||||
subfamily_PTPRN_pd | Subfamily PTPRN | 1543-1802 | 8.5e-51 | 167.4 | In-house | 33-292 (297) | alignment | ||
Range on Protein: 1543-1802
Range on HMM: 33-292/297.0
KQFEKLNSIDvAIPSQYISASLPVNRAKNRYPDILPYESYRVRLLMLPGVSGSDYINASYV-DGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVML
|..| | . . | || |. . | |||. ..|||. ||.| . ||||||| . | | .| |||||..|| |||.|.||. | ||.|
kewealcaye.aepstkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplastvadfwqmvweqGvvvivnl
CGLVEDGKDQSVQYWPKDQLTQYGDMFIETISET-DTGFYVIREITITHTkQGNEVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAHHLfGGGPVVV
. | |.| | .|||.. |. .. .|| . |..| . . | .| | . |||. | |. .|... .|... |.|.. |.||
trleeegvkqckrywpdeGsevyhiyevhlvsehiwcddylvrsfylknl.qtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrG.rscpivv
HDSSSVGRSGTFCIINIVIERLK-VEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYL
| |. .||.|....|..|..||. ||| |. || . ||.|. |||.|......| .
hcsdGaGrtGvyilidlvlnrllkGvkeidiaatlehlrdqrpglvktkdqfefaltavaeev
|
|||||||||
0043147 | (Phosphotyrosine protein) phosphatases II | 1296-1493 | 2.7e-47 | 156.0 | In-house | 3-154 (172) | alignment | ||
Range on Protein: 1296-1493
Range on HMM: 3-154/172.0
EGSDYINANYIDGYGSRDTYIACQGPLAETSPDFWRMIWEQKTSCIVMLTNCvekgrpkchqywpqtgsttfgeltvtiidqqvlayytirtfkINNKDD
||||||||.|.|.| | .||.|||| .| .|||||..|.. ..||.||.. .....
egsdyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltel..........................................lydpel
ESFEVKQFHYTAWPDFGVPdHPNPIISFIRRVNN---STHTGPLVVHCSAGVGRSGTFIAIQSMMlmmeteGKVDVFNFVLDMRHKRNYMVQTEAQYMFV
.. .. |..|. |||.||| ... ...|.. ... || .|||||||||.||..|. |. ...... | .|.||...||.. ||.|.
lerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml......lglsleeavalvrekRpgavqnpsqyrfl
H
.
y
|
|||||||||
0046846 | (Phosphotyrosine protein) phosphatases II | 1292-1499 | 7.1e-47 | 154.7 | In-house | 6-172 (176) | alignment | ||
Range on Protein: 1292-1499
Range on HMM: 6-172/176.0
IPGIEGSDYINANYIDGYgsrdTYIACQGPLAETSPDFWRMIWEQKTSCIVMLTNCVEKGRPKCHQYWPQTGSTTFgeltvtiidqqvlayytirtfkin
. ...||||||.|.|. .||.|||| .| .||..|..|.. ...|.||..||.|| ||..|||. . .
lgldldldyinanlilgs....rpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgi........................
nkddesfevkQFHYTAWPDFGVPDHpNPIISFIRRVNNSTHTG-PLVVHCSAGVGRSGTFIAIQsmmlMMETEGKVDVFNFVLDMRHKRN-YMVQTEAQY
|.... |||.||||. . ...... ... . | | .||||||.||.||..|. ..|.| ..|.. . .| .| ..|||..||
..........qylhlpwpDhgvpdl.elllellefirealkeggpvlVHCsaGigRtgtlvaay....llelekglsveealalvreqRplgavqtpeQy
MFVHDSLVEL
|... . .|
rflyefelll
|
|||||||||
0049772 | (Phosphotyrosine protein) phosphatases II | 1244-1503 | 2.4e-46 | 154.3 | In-house | 20-283 (314) | alignment | ||
Range on Protein: 1244-1503
Range on HMM: 20-283/314.0
HLFSEEYELITIKSPSLPHEASQQTCNIEKNRYGNINSFDeTRVVLtKIPGIEGSDYINANYIDGYgsrDTYIACQGPLAETSPDF----------WRMI
|... . . |.| . .... .|..|||| .| .| .||.| . ...|||||||.|.||. ..||.|||| .| || |||.
klllvlnrrslsvlpeltilvadlflnrdknryldilpad.nrvil.pglpvsgsdyinasyvdgf...lkfIatqgpleitvvdfreepvlyyngwrmv
--WEQKTSCIVM---------------------LTNCVEKGrpkchqywPQTGSTTFGELTvtiidqqvlayytirtFKINNKDDESFEVKQFHYTAWPD
..... ||| |... ..| .. .. .| ...... . .. ..... .||
lrgdlnvrdivmsrdevladelsrLdaAlgKtpllildgng........neptaadlellk................eelydpelferlgikylripvpD
fGVPDHPNPIISFIRRVNNSTHTGPLVVHCSAGVGRSGTFIAIQSMMLMMetegKVDVFNFVLDMRHKRN-----YMVQTEAQYMFVHDSLVELIKVG
| .. .. . .|.. ... ||..|||.||.||.|||... .|. . .|.. . |.| || .... || |... | |..|
.gsaplledfdeflefieeadkggpvlvHCkaGkgRtgtfvvaaylmkll....gvsleealedvrlkRpinpnpgfieqleqyefilealleylkfl
|
|||||||||
subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 1246-1499 | 3.4e-46 | 152.4 | In-house | 8-258 (267) | alignment | ||
Range on Protein: 1246-1499
Range on HMM: 8-258/267.0
FSEEYELITIKSPSLPH-EASQQTCNIEKNRYGNINSFDETRVVLTKipgiEGSDYINANYIDGYGSRDTYIACQGPLAETSPDFWRMIWEQKTSCIVML
. .|.|||. |. | . | |.||. . .|.|||.| . . .|||| |..|| . ..|. |.|| | ||. .| .|| . ||.|
iekefelikkisdtsstisqsiaeknqernrlddnlpyddtrvilrt....keeeyinasyvegyktknafivtqdplkntitdfltvihdqkvpvivll
TNCVEKGRPkchQYWP-QT-GSTTFGELTVTIIDQQVLAYYTIRTFKINNKDDESFEVKQFHYTAWpDFGVPDHP--NPIISFIRRVNNSTHTGPLVVHC
|. . . ..|| . . . .||| .. | | |.... |.. ...| ..| | . . ..| .|.. . . . ||||.|
tkvftdnir...lfwPPkmgqakkyqdltvehslekeendyqiitlelkfknesahnvtlyyykkw.nintnnkpylkplfgilaknqlengnrPlvvac
SAGVGRSGTFIAIQSMMLMMETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVEL
|.||||||||. |.|.. . ||| .|.|.|.. .|..| .|.| .|...|..|.|
sdGvGrsGtflvidsqleraktegvsdifdflrkirsqriglvdtkeryiyihellaey
|
|||||||||
0051429 | (Phosphotyrosine protein) phosphatases II | 1593-1805 | 1e-45 | 151.9 | In-house | 2-228 (272) | alignment | ||
Range on Protein: 1593-1805
Range on HMM: 2-228/272.0
SGSDYINASYVDGYLR---CNQFIMTQGPLSNTVDDFWRMiWEHRVSAIVMLCGLVEDGKDQSVQYWP------------KDQLTQYGDMFIETISETDT
. |.||||..|.|| | . .. ..||| .|..||||. .|.....||.|....| |... .||| .. ||.... ..||. .
plsgyiNardvggygrvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseell
GFYVIREITITHTKQGNEVRNIKQFHYTDWSENKTPPTTgaLMDMIVLVQKahhlfgGGPVVVHDSSSVGRSGTFCIINIVIERLKVEGMID--------
.|..||...|.. . .|.| . ..||||| .|. . | ... |... ||||.|| |. ..|.||.. . ...... | ..|
ldyilrellltlllsagearevmhlhytdwpdhgvpqea..llellellld......ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnly
IFFTIHALRRKHPGIVANYDQFKFCYQTIVEYLESF
.. ... ||.. ||.| ...|..|.|. ..|.|.|.
leeaveelraqrpgavqteeqylflyeallellrsl
|
|||||||||
subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 1558-1802 | 1.9e-45 | 149.9 | In-house | 36-236 (392) | alignment | ||
Range on Protein: 1558-1802
Range on HMM: 36-236/392.0
QYISASLPVNRAKNRYPDILPYESYRVRLLMLPGVSGSDYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCGLVEDGkdqsvqywp
. .| ..| |||| .||||.| ||.| .. .. |||.||||.... . .| .||| . ..||||||.....|..|.|. | |
pqtvaqkeinlkknryknilpydsarvkleviddipdsdylnasyipsfdnekayiasqgpnaaslddfwrmvfqenvttiamvtklkegd.........
kdqltqygdmfietisetdtgfyvireitithtkQGNEVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAHHLFGgGPVVVHDSSSVGRSGTFCIINI
.|...| . |||.|.| .. | | .|. .| |. . . |...| |. |||.| |.
..................................kgddartvaqfhftewPdkdvpkhtssllkfikevkadfGqyt.hpliihcsagvgrtgvvisids
VIERLKVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYL
|. . | |.|.| . .|||.| .| .|. | | ...| |
vvahakktrmvdvfnfvtnirrkrpymvqtkeqyafiygavledl
|
|||||||||
subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 1543-1803 | 6.6e-45 | 148.2 | In-house | 10-260 (267) | alignment | ||
Range on Protein: 1543-1803
Range on HMM: 10-260/267.0
KQFEKLNSIDVAipSQYISASLPV-NRAKNRYPDILPYESYRVRLLmlpgVSGSDYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVML
|.||... | |. || |.. |...||. | |||. || | . .|||||||.|| . |.||.||.||.||. ||. .| ...|. ||.|
kefelikkisdt..sstisqsiaeknqernrlddnlpyddtrvilr....tkeeeyinasyvegyktknafivtqdplkntitdfltvihdqkvpvivll
CglvEDGKDQSVQYWPKD--QLTQYGDMFIETISETDTGFYVIreITITHTKQGNEVRNIKQFHYTDWSENKTppTTGALMDMIVLVQKAHHLFGGGPVV
..|. ..|| | .| |. .| | . | | ||. . . .|. ..| | | | .. .. | . |. |.|
t...kvftdnirlfwPPkmgqakkyqdltvehslekeendyqi..itlelkfknesahnvtlyyykkwnintn..nkpylkplfgilaknqlengnrPlv
VHDSSSVGRSGTFCIINIVIERLKVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYLE
|. | ||||||| .|. .||.| ||. ||| . .| . .|.| ... .......|| |
vacsdGvGrsGtflvidsqleraktegvsdifdflrkirsqriglvdtkeryiyihellaeyae
|
|||||||||
0049260 | (Phosphotyrosine protein) phosphatases II | 1305-1494 | 5.5e-44 | 144.8 | In-house | 1-144 (152) | alignment | ||
Range on Protein: 1305-1494
Range on HMM: 1-144/152.0
YIDGYGSRDTYIACQGPLAETSPDFWRMIWEQKTSCIVMLTNCVEKGRPKCHQYWpqtgsttfgeltvtiidqqvlayytirtfkinnkddesfevkQFH
.||||. .||.|||. .| .|||||..|.. ..|||||...|.|..||.||. |..
fidgyampfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi..........................................qyl
YTAWPDFGVPDHPNPIISFIRRVNN--STHTGPLVVHCSAGVGRSGTFIAIQSMMlmmeteGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHD
.. |||.||||.. .. ... .. || .|||||||||.||..|. |. .|.....| .| ||...|... |..|...
hlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpgqlrflye
|
|||||||||
subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 1565-1800 | 2.6e-43 | 142.9 | In-house | 5-238 (239) | alignment | ||
Range on Protein: 1565-1800
Range on HMM: 5-238/239.0
PVNRAKNRYPDILPYESYRVRLLMLPGVSGSDYINASYVDGYLRC-NQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCGLVEDGKDQSVQYWPkDQLTQ
||.||||| .|. |. || | | ||||||||. | . .| ||| .. . |||||.|. | |||| ||.| | . |||| | ..
rvnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywp.dstsk
YGDMFIeTISETD-TGFYVIREITITHTKQGNEvRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKaHHLFGGGPVVVHDSSSVGRSGTFCIINIVIERL
| .. . |. .|. |.|| . ... | .| | . |.|.| | .. | . |.. . . | | | | |.| |. |||.|.| .|. .. .
ycnlrv.tlrktevfadyiirtfvmsqvgqtee.ryvyqyhftvwpdkgvpqyatavlglrrkitk.dslpgarpwvihcsagvgrtgaflvidamlrqa
KVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVE
| . .||| ..|.| .| .| .|. | . ...|
kkqktvdifnyvkairedrphmvqtseqyvfihlavle
|
|||||||||
subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 1565-1799 | 3.2e-43 | 142.6 | In-house | 6-238 (239) | alignment | ||
Range on Protein: 1565-1799
Range on HMM: 6-238/239.0
PVNRAKNRYPDILPYESYRVRLLMLPGVSGSDYINASYVDGYLRC-NQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCGLVEDGKDQSVQYWPkDQLTQ
||.||||| .|. |. || | | ||||||||. | . .| ||| .. . |||||.|. | |||| ||.| | . |||| | ..
rvnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywp.dstsk
YGDMFIeTISETD-TGFYVIREITITHTKQGNEvRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKaHHLFGGGPVVVHDSSSVGRSGTFCIINIVIERL
| .. . |. .|. |.|| . ... | .| | . |.|.| | .. | . |.. . . | | | | |.| |. |||.|.| .|. .. .
ycnlrv.tlrktevfadyiirtfvmsqvgqtee.ryvyqyhftvwpdkgvpqyatavlglrrkitk.dslpgarpwvihcsagvgrtgaflvidamlrqa
KVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIV
| . .||| ..|.| .| .| .|. | . ...
kkqktvdifnyvkairedrphmvqtseqyvfihlavl
|
|||||||||
0041856 | (Phosphotyrosine protein) phosphatases II | 1567-1803 | 3.4e-43 | 142.7 | In-house | 1-172 (182) | alignment | ||
Range on Protein: 1567-1803
Range on HMM: 1-172/182.0
NRAKNRYPDILPYESYRvrllmlpgvsGSDYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCglvedgkdqSVQYWPkdqltqygd
|. ||||.|||||. | ..|||||....|.|. ..||.||||| .|| ||.||..|.....||.|. ...|||
nldknrysdilpydhsr..........dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt.........eelywp.........
mfietisetdtgfyvireitithtkqGNEVRNIKQFHYTDWSENKTPPtTGALMDMIVLVQKahhlfGGGPVVVHDSSSVGRSGTFCIINIVIERlkveG
.. |.. |..|. | . .|. . | |.| |.. ||||.|| | |||.||.... ..... |
..........................ellerlgiqylylpwpDhgvpd.ldelldfieevle.....eggpvlVHCsaGvgRtgtlvaaylmkkl....g
mIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYLE
.... ... .|.. ||.| . .|. |... . |.|.
.vsleeavklvrsrRpgmvitpnqyfflqlallelll
|
|||||||||
subfamily_ptpA1_pd | Subfamily ptpA1 | 1237-1459 | 6.8e-42 | 138.7 | In-house | 14-255 (418) | alignment | ||
Range on Protein: 1237-1459
Range on HMM: 14-255/418.0
RLHANTDHLFSEEYELITIK-SPSLPHEAsQQTCNIEKNRYGNINSFDETRVVLTKIPGIEGSDYINANYIDGYGSRdTYIACQGPLAETSPDFWRMIWE
. | . | ||. |. || | .. | |||| || . ||| | || ||||||||||||| . .|. |||| .| |||||.||
knhikcihkikeefrlleesvgpsetseg.dkkhntsknrytnilpvnhtrvqlkkiqdkegsdyinanyidgaypk.qfictqgplpntiadfwrmvwe
QKTSCIVMLTNCVEKGRPKCHQYWPQ-----------TGSTTFGELTVTIIDQQVLAYYTIRTFKINN-KDDESFEVKQFHYTAWPDFGVPDHPNPIISF
.. ||||. |. | || .|||. | || .| ... | | .| . |. .. |..| |||. .||| .|. .
nrcriivmlsresencrikcdrywpeqiggeqfsiygngnevfgtysvelveviqdpereiitrnirltfegetrditqyqyegwpdhnipdhtqpfrql
IRRVNN--------STHTGPLVVHCSAGVGRSGTFIAIQSMMLM
.. . | | . |..|||||||||.||| . ||
lhsitnrqnqiipssdrnvpiivhcsagvgrtgtfctavimmkk
|
|||||||||
0049772 | (Phosphotyrosine protein) phosphatases II | 1559-1807 | 1.5e-41 | 138.5 | In-house | 38-285 (314) | alignment | ||
Range on Protein: 1559-1807
Range on HMM: 38-285/314.0
YISASLPVNRAKNRYPDILPYEsYRVRLlMLPGVSGSDYINASYVDGYlrcNQFIMTQGPLSNTVDDF----------WRMI--WEHRVSAIVM------
. |.|..|| ||||.||||.. ||.| .||||||||||||||. ..|| |||||..||.|| |||. ....| |||
ilvadlflnrdknryldilpad.nrvil.pglpvsgsdyinasyvdgf...lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivmsrdevl
---------------LCGLVEDGkdqsvQYWPKDQLTQYGdmfietisetdtgfyvireiT-------IthtkqgneVRNIKQFHYTDWSEnKTPPTTGA
|..| . | ... | .. . |.. ........ ..|..
adelsrLdaAlgKtpllildgng.....neptaadlellk....................eelydpelf........erlgikylripvpD.gsaplled
LMDMIVLVQKAhhlFGGGPVVVHDSSSVGRSGTFCIINIVIERLkveGMiDIFFTIHALRRKHP-----GIVANYDQFKFCYQTIVEYLESFDK
. ... ....| ||||.|| .. .||.|||... ... .| |. .. ... .|.|.| | . ...|. |... . |||. . |
fdeflefieea...dkggpvlvHCkaGkgRtgtfvvaaylmkll...gv.sleealedvrlkRpinpnpgfieqleqyefilealleylkflkk
|
|||||||||
subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 1246-1498 | 1.6e-41 | 136.8 | In-house | 13-267 (281) | alignment | ||
Range on Protein: 1246-1498
Range on HMM: 13-267/281.0
FSEEYELITIKSPSLPHEASQQTCNIEKNRYGNINSFDETRVVLT-KIPGIEGSDYINANYIDGYGSRDTYIACQGPLAETSPDFWRMIWEQKTSCIVML
| .|. . || . .| | .|||| || .| .|| | |.| . .||| |||| . || ||| || |||||||...|..||||
fkqefsnlpgdppsdlctvfnqpvnnkknrylnipcldisrvqlkvkmpnknstdyihanyirspflkrgyiltqgpkketradfwrmiwqenttaivml
TNCVEKGRPKCHQYWPQTGS--TTFGELTVTIIDQQVLAYYTirTFKIN-NKDDESFEVKQFHYTAWPDFGVPDHPNPIISFIRRVNNstHTGPLVVHCS
. .| | || .|.|. | .|.|. | | | ..| . |. . .. . |||. ||. . .. .|.. .. | |.|||
cqfletnrekcaeyfprnahcclqfdklsvsyedstvnkslv..ttrlnlsyegetrlithwlwkewpdwqvpessevmlkilrkira..rstppvihcs
AGVGRSGTFIAIQSMMLMMETEGK-VDVFNFVLDMRH-KRNYMVQTEAQYMFVHDSLVE
||||||||..|.. . . . |. . | .| | ||| |||.. |..
agvgrsgtlmaveialqsihshftlpdikqivshlrvtgraasvqtlqqymliwkvlld
|
|||||||||
0044763 | (Phosphotyrosine protein) phosphatases II | 1282-1501 | 7.9e-41 | 135.0 | In-house | 2-172 (178) | alignment | ||
Range on Protein: 1282-1501
Range on HMM: 2-172/178.0
FDETRVVLTKIPGIEGSDYINANYIDGYgsrdTYIACQGPlaetsPDFWRMIWEQKTSCIVMLTNCVEKGRPKCHQYWPQTGSttfgeltvtiidqqvla
.|.|||.|....|.|.||||||..|... |.....| .|......|.. ..||.||. .| |..||..|||. .
ldrtrvllsnleglersdyinaseilpg....lylgslpp.....addlellkelgithivnlteelelgflkcdpywpeeag.................
yytirtfkinnkddesfevKQFHYTAWPDFGVPDHPNPIISFIRRVNNS--THTGPLVVHCSAGVGRSGTFIAIQSMMLMmetegKVDVFNFVLDMRHKR
|.... .||.|||| . . |.. ... .. || .||||||||||||..|. |. . ...... . .| .|
...................iqylhipipDhgvpdllehflefvefieealdekggpvlVHCsaGvgRsgtlvaaylmkkl.....glsleeaielvrerR
NyMVQTEAQYMFVHDSLVELIK
. .|... |. .... .| |
p.ivpnpgqlrqLyefelrllk
|
|||||||||
0051082 | (Phosphotyrosine protein) phosphatases II | 1297-1495 | 9.8e-41 | 134.1 | In-house | 2-148 (151) | alignment | ||
Range on Protein: 1297-1495
Range on HMM: 2-148/151.0
GSDYINANYIDGYgsrdtYIACQGPlaetSPDFWRMIWEQKTSCIVMLTNCVEKGrpKCHQYWPQTGsttfgeltvtiidqqvlayytirtfkinnkdde
|||||..|..|. .....|| ..||.....|.. ..||.|.. .| | .|..|.|..|
lsdyinfsyvtgg.....lyrsggp....ladflellkelgiktivnlrseeerg..ycpeylpelg.................................
sFEVKQFHYTAWPDFGVPDHPNPIISFIRRVNNsTHTGPLVVHCSAGVGRSGTFIAIQSMMLMmetegkVDVFNFVLDMRHKRNYMVQTEAQYMFVHDS
.||...... |||.|.|.... ...|.. ... . ||..||||||.||.||..|. |.|. |... . ..| || ..||.. |..|..
.ievlhipildwpdpglplsfdavleflellld.kkngpvlvHCsaGkgRTGtlvalylmllg......vsleealeeyrlkrpgvvqpnqqflfqlfa
|
|||||||||
subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 1255-1500 | 1.6e-40 | 133.6 | In-house | 39-290 (310) | alignment | ||
Range on Protein: 1255-1500
Range on HMM: 39-290/310.0
IKSPSLPHEASQQtcNIEKNRYGNINSFDETRVVLtKIPGIEGSDYINANYIDGYGSRDTYIACQGPLAETSPDFWRMIWEQKTSCIVMLTNCVEKGRPK
. .|| .|| .. .. |||| .. |..|| | || ||| |||. |.|.| .|||| | ||||||..... |..| . .|.||||
kqdssltyeaykk..ymhknrysdvvcldtsrvkl.kidksryedyihanyvktnylrstficsqgplqhtiidfwrmifqeraesilllckvgeegrpk
CHQYWPQTGST-TFGELTVTIIDQQVLAYY---TIRTFKINNK--D-----DESFEVKQFHYTAWPDFGVPDHPNPIISfiRRVNNSTHTGPLVVHCSAG
| ||| | | |.| . || . . . || .| | . . |. .. ||| |||| . .|. || |||||||
cvgywpslgvtetygcirvtnlsesseefeicnlavtfvpdnvpvdeqpanlkelrvslikwpnwpdrgvpdekchtvp..qrllaqvrhgpcvvhcsag
VGRSGTFIAIQSMMLMMETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELI
..| .. .|.. . .. |||. . . .....| .||| ||.... . .
kdrlyvvvalklkidkldrglkvdaeevktellksraiciqtelqyliidrvriifa
|
|||||||||
0036282 | (Phosphotyrosine protein) phosphatases II | 1594-1796 | 1.8e-39 | 130.6 | In-house | 1-164 (174) | alignment | ||
Range on Protein: 1594-1796
Range on HMM: 1-164/174.0
GSDYINASYVDGYLRCNQFIMTQGPLSntvddFWRMIWEHRVSAIVMLCGLVEDGKDQSVQYWPKdqltqygdmfietisetdtgfyvireitithtKQG
||||||||..|.. . . .| .||||. ||.|..|......|||. ..|.|. .||| ..
gsdyinaspldlsyitprliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe................................lre
NEVRNIKQFHYTDWSENKTPPTTGaLMDMIVLVQKAHHLFGGGPVVVHDSSSVGRSGTFCIINIVIERLKvEGMIDIFFTIHALRRKHPGIVANYDQFKF
..|.. |..|. | . .|... | ... .|..|. .||||.|| | |||.||.... ... .|. |...|.. ....||.. ||.| . .|..|
dlerlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtpsQyrf
CYQ
.|.
lyy
|
|||||||||
subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 1267-1500 | 1e-38 | 127.9 | In-house | 45-287 (305) | alignment | ||
Range on Protein: 1267-1500
Range on HMM: 45-287/305.0
QTCNIEKNRYGNINSFDETRVVLtkiPGIEGSDYINANYIDGYGSRDTYIACQGPLAETSPDFWRMIWEQKTSCIVMLTNCVEKGRPKCHQYWPQTGS--
.. . .|||| .. .|. || | | .|| |||. .| .| || .| ||| | ...| | || | .||| ||..|..
eaqeagknrykdvgcldnnrvkl...egpwpheyihanyvstptnpkrfictqaplektcadfwymclqdkveaifmlcnllekgakkcleyfaskdkdv
TTFGELT----VTI-------IDQQVLAYYTIRTFKINNKDDESFEVKQFHYTAWPDFGVPDHPNPIISFIRRVNNSthTGPLVVHCSAGVGRSGTFIAI
.| | | . . .. | | . |. .. |...|. ||| ||| . |. .. . | ||.|||||||.||.|. . .
lefeekgqkisvkfessvtlkfrkdakakvtetvlviegpgekarkvthyhwidwpdrgvpaadlailellekarps..kgpivvhcsagigrtgsvvml
QSMMLMMETEGKVDVFNF-VLDMRHKRNYMVQTEAQYMFVHDSLVELI
. .. . . ... . . .| .|| .||.|||.|||. ... .
eyildqllagqiiedtdkilqkireqrnnsiqtdaqylfvhqvilnyf
|
|||||||||
subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 1542-1805 | 2.8e-38 | 126.2 | In-house | 28-286 (290) | alignment | ||
Range on Protein: 1542-1805
Range on HMM: 28-286/290.0
PKQFEKLNSIDVAIPSQYISASLPV-NR--AKNRYPDILPYESYRVrlLMLPGVSGsDYINASYVDGYlrCNQFIMTQGPLSNTVDDFWRMIWEHRVSAI
| |. . .|.||. .. | |||| |. . || .. | | ||. | ||.| ||.|||.| .|| |.|||. ...|.||
elakeyleklkpylpvqylerkifdkntefkknrykdvvcndktrv..ilkdGydG.dyvhanyvkGl..kamfiltqGalkdtvidiwrmvlqekvaai
VMLCGLVEDGKDQSVQYWPKD--QLTQYGDMFIETISETDTGFYVI-REITITHTKQGNEvRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAHhlfgg
|||| |.|||| . ||.|. . .|.. . |.| .| . ... . ..| | .| .. | .. . .| ||. .. ..||
vmlceliedGkakceqyypekeGevltfGeitvlcseeddkdaniikktlsvrdkdsGke.hklkhlkikswpdksvalstlallrtlrilrkas.....
GPVVVHDSSSVGRSGTFCIINIVIERLKVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYLESF
|||||| |. .||.||| |.. .. | .|. .. |||. . | |. . .... .|
GpvvvhcsaGiGrtGtfvaievglqilldGkeldlldlvralrnsrlnsvqvdiqylalveilldlGkdf
|
|||||||||
0043147 | (Phosphotyrosine protein) phosphatases II | 1593-1796 | 3e-38 | 126.6 | In-house | 3-155 (172) | alignment | ||
Range on Protein: 1593-1796
Range on HMM: 3-155/172.0
SGSDYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCGLvedgkdqsvqywpkdqltqygdmfietisetdtgfyvireititHTKQ
.|||||||||.|.| ..||.|||||.||..|||||..|. ...||.|..| .
egsdyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltel............................................lydp
GNEVRNIKQFHYTDWSENKTPpTTGALMDMIVLVQKAHHLFGGGPVVVHDSSSVGRSGTFCIINIVIerlkvEGMiDIFFTIHALRRKHPGIVANYDQFK
...|.. |..|. | . .| .. |.... .......| ||||.|| | |||.||.... ... .|. ... ... .|.| ||.| | .| .
ellerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml.....lgl.sleeavalvrekRpgavqnpsqyr
FCYQ
|.|.
flyy
|
|||||||||
subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 1267-1498 | 1.2e-37 | 124.3 | In-house | 52-287 (305) | alignment | ||
Range on Protein: 1267-1498
Range on HMM: 52-287/305.0
QTCNIEKNRYGNINSFDETRVVLTKIPgieGSDYINANYIDGYGS-RDTYIACQGPLAETSPDFWRMIWEQKTSCIVMLTNCVEKGRPKCHQYWPQTGST
.| |||| .. |.. | | | . |||| |||. .|..|||| .| .|| |. ..| |||| . || |. || |||| .
adiaitknryqdvpcqdqsavkldkps...psdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkveqivmlcktvelgklkcaqywpaaqge
TFgELTVTIIDQQV--------LAYYTIRTFKINNKDDESFEVKQFHYTAWPDFGVPDHPNPIISFIRRVNNSThtGPLVVHCSAGVGRSGTFIAIQSMM
|| |. ..| | | ..... |... |.....| ||| ||| . .. . | |.|||||||.||.|| .||. ..
kl.elksgivvenvsgskpmerdaeiqitllnltysgdqkmsvrhlqwtewpdrgvppckltslellsairgsk..vpivvhcsagigrtgtivaieyil
LMM-ETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVE
. | . ..| .| .| . .|.. ||.|.| ...
ekiaenkpcppmpelvkalrdqrafsiqndvqylfihrvmln
|
|||||||||
PTPc_DSPc_SM00012 | 1400-1497 | 3.4e-36 | 119.0 | In-house | 2-104 (105) | alignment | |||
Range on Protein: 1400-1497
Range on HMM: 2-104/105.0
VKQFHYTAWPDFGVPDHPNPIISFIRRVNNSTH----TGPLVVHCSAGVGRSGTFIAIQSMMLMMETE-GKVDVFNFVLDMRHKRNYMVQTEAQYMFVHD
||..|||.|||.|||.....|....| |..... ..|.||||||||||.|||.|. .. ..|.| ..||.|..| .|..|. |||||.||.|...
vkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylflyr
SLV
|
all
|
|||||||||
subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 1268-1508 | 3.6e-36 | 119.6 | In-house | 33-279 (285) | alignment | ||
Range on Protein: 1268-1508
Range on HMM: 33-279/285.0
TCNIEKNRYGNINSFDETRVVLTKipgiEGSDYINANYIDGYGS-RDTYIACQGPLAETSPDFWRMIWEQKTSCIVMLTNCVEKGRPKCHQYWPQTG--S
.| . ||| .. .|||||| . ||| |... | . |||. |||| || |||.||...| . ..|| .| | || |.|.
eanpdlnryadvrcieetrvvlkn....hdrdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyypeklgev
TTFG--ELTVTIIDQQVLAYYTIRTFKINNKDDESFEV---KQFHYTAWPDFGVPDHPNPIISFIRRVNNS-THTGPLVVHCSAGVGRSGTFIAIQSMML
|| |.|.| .. .| . .. . | .| | | .. . ||| |. |.| . . |.. . |..|||||||||. ||. |. .
vkfgkyeitlteckeeaiagtilnaltvintedasseplymnhvqvpwwpdqlapedarpmielykwvkkvnpkekpicvhcsagvgrtatfvgidyati
MMETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVEL-IKVGNSEQT
. . ...... | .|| | ||. |..|.. |.| | | |.|
rimenpniemldivremramrfqavqshmqflflyvvlmeyfigegvvert
|
|||||||||
subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 1269-1498 | 5.2e-36 | 119.2 | In-house | 42-269 (288) | alignment | ||
Range on Protein: 1269-1498
Range on HMM: 42-269/288.0
CNIEKNRYGNINSFDETRVVLTkipgIEGSDYINANYIDGYGSRDTYIACQGPLAETSPDFWRMIWEQKTSCIVMLTNCVEKGRPKCHQYWPQ-TGST-T
| ..|| |. | ||| |. . ||.|| . . | .| || | .|.|. |. ||||.. .|||..| .|.| | .
anptrdryenlprcditrvkls....ddpdfyiaanvvssakykrrlicaqaPlngtieelWkmllesdveyivmlcellekGkeksaeyfPsklGekar
FGELTVTIIDQQ--VLAYYTIRTFKINNKDDESFEVKQFHYTAWPDFGVPDHPNPIISFIRRVnnSTHTGPLVVHCSAGVGRSGTFIAIQSMMLMMETEG
.| | . ... . .. ...|... .|. ||. |. |.| |||. . . .. .. ... |.|||.||||||.||.| | .. .. .
igrlctvvkkkradidklvkvsllriskegeekvivkilhlleWdddgvPenylsplrllevl..kslqkPivvhssaGvGrtgtlililialeslrldd
KVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVE
. . ... .| .| .||| ||..|| . |
flgirsllaklreerfkaiqtemqylyvhrcvle
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 1268-1430 | 2.4e-35 | 116.7 | In-house | 27-193 (319) | alignment | ||
Range on Protein: 1268-1430
Range on HMM: 27-193/319.0
TCNiEKNRYGNINSFDETRVVLTKIPGIEGSDYINANYIDGYGS-RDTYIACQGPLAETSPDFWRMIWEQKTSCIVMLTNCVEKGRPKCHQYWPQT----
|.. .|.|. |. . |||||| .|. . . |..|.|. || . . |||.| .| ..| ||||..|||.. || ||. |.| .| .|.|
tsk.dksrvinvvPlPetrvvlqrigdddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlselGikvcaeylPtketld
GSTTFGELTVTIIDQQVLAYYTIRTFKINNKD-DESFEVKQFHYtAWPDFGVPDHPNPIISFIRRVNNS
. ..|.. ||. ...| | | |. ... | .|| |. . | |.. .|| .....|. . .|..|
ntslyGdilvtlkgrevkdryaistlllkrvdkeesrelthywy.kwleaevPaeeaaliamllevrss
|
|||||||||
0049260 | (Phosphotyrosine protein) phosphatases II | 1602-1796 | 1.2e-33 | 111.3 | In-house | 1-144 (152) | alignment | ||
Range on Protein: 1602-1796
Range on HMM: 1-144/152.0
YVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCGLVEDGKDQSVQYWpkdqltqygdmfietisetdtgfyvireitithtkqgnevrnikQ
..||| . ..|| ||||..||..|||||..|. ...||||. |.|.||.. ||. |
fidgyampfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi............................................q
FHYTDWSENKTPPTTGALMDMIVLVQKAhHLFGGGPVVVHDSSSVGRSGTFCIINIVIerlkveGMIDIFFTIHALRRKHPGIVANYDQFKFCYQ
.... | . .|. . |.... ...|. | ||||.|| | |||.||.... ... .... .. .|.| ||.| | .| .|.|.
ylhlpwpDhgvpdlsqlllflllfiekl.aldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpgqlrflye
|
|||||||||
0046846 | (Phosphotyrosine protein) phosphatases II | 1585-1803 | 1.5e-33 | 111.4 | In-house | 2-174 (176) | alignment | ||
Range on Protein: 1585-1803
Range on HMM: 2-174/176.0
RLLMLPGVSGSDYINASYVDGYLrcnqFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCGLVEDGKDQSVQYWPKdqLTQYGDmfietisetdtgfyvire
||..| ..|||||....|.. .| ||||| .|. ||..|..|....|.|.|. .|| |. . .||| |...|
rlrllgldldldyinanlilgsr....piatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpe..leklgi..................
itithtkqgnevrnikQFHYTDWSENKTPPTtGALMDMIVLVQKAHHlfGGGPVVVHDSSSVGRSGTFCIINivieRLKVEGMIDIFFTIHALRRKHP-G
|.....| .. .|. .|.... ....| . ||||.|| | .||.||.... |. | .... ... .|...| |
................qylhlpwpDhgvpdl.elllellefirealk..eggpvlVHCsaGigRtgtlvaay....llelekglsveealalvreqRplg
IVANYDQFKFCYQTIVEYLE
.| . .| .|.|. . ..|.
avqtpeQyrflyefellllk
|
|||||||||
subfamily_ptpA1_pd | Subfamily ptpA1 | 1564-1762 | 2.6e-33 | 110.4 | In-house | 44-256 (418) | alignment | ||
Range on Protein: 1564-1762
Range on HMM: 44-256/418.0
LPVNRAKNRYPDILPYESYRVRLLMLPGVSGSDYINASYVDGYLrCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCGLVEDGKDQSVQYWPK----D
| .|||| .||| . ||.| . ||||||| |.|| .||| ||||| ||. |||||.|| |. |||| |. . . .|||. .
kkhntsknrytnilpvnhtrvqlkkiqdkegsdyinanyidgay.pkqfictqgplpntiadfwrmvwenrcriivmlsresencrikcdrywpeqigge
QLTQYGDM---F-------IETISETDTGfYVIREITITHtkQGnEVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQ-KAHHLFG----GGPVVVHDSS
|.. ||. | .| | . . . |.| .| .| | |.| |..| | . . | | . ... . . .. |..|| |.
qfsiygngnevfgtysvelveviqdpere.iitrnirltf..eg.etrditqyqyegwpdhnipdhtqpfrqllhsitnrqnqiipssdrnvpiivhcsa
SVGRSGTFCIINIVIERL
|||.|||| |....|
gvgrtgtfctavimmkkl
|
|||||||||
subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 1560-1802 | 2.6e-32 | 107.1 | In-house | 34-277 (307) | alignment | ||
Range on Protein: 1560-1802
Range on HMM: 34-277/307.0
ISASLPVNRAKNRYPDILPYESYRVrLLMLPGVSgSDYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCGLVEDGKDQSVQYWPKD
.. | |||| |. . |. .. ..|.. |||| | |. .. ..|| .|||| ||. .|| |. ...| ...||| ..| .| . |||| .
tveafsantdknryqdvkcqdkgri.vvkfdgla.sdyihanylgiaikpkkficaqgplentqysfwamaiqekvesvimlckvielakikceqywple
Q--LTQYGDMfIETISETDTGFYVIR------EITITHTKQGNEVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQkahhlFGGGPVVVHDSSSVGRSGT
. .|. .||| .. | . ..| . . ... | |... ...| .. .|.. . .... |. . ||||| |. ||||||
egqklvfgea.pntisvanlgakklapdedlinvttlkvdwaqksrtiqhlqwenwpdrgvpqinltainlleavr.....ydtnpvvvhcsaGvGrsGt
FCIINIVIERL-KVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYL
| .| ... . . |. .. || . . . . |. . .. ..||.
ivaislvqdkmiaGinckdmkklveelrsqrhyaiqteaqylylhrvlleyf
|
|||||||||
subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 1272-1500 | 5.2e-32 | 105.8 | In-house | 52-282 (301) | alignment | ||
Range on Protein: 1272-1500
Range on HMM: 52-282/301.0
EKNRYGNINSFDETRVVLTKipgiEGS-DYINANYIDGYGSRDTYIACQGPLAETSPDFWRMIWEQKTSCIVMLTNCVEKGRPKCHQYWPQTGSTT--FG
.|.|| .. .| | . . .| | ||.|. | . .|| |||| .|| ||| |. . ||||.. ||| ||..| |.. | . |
dkhryptvPckPstaveviv....dGkrvPihanwiptsGhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkisekldig
ELTVTIIDQQVLAYYTIRTFKINNKDD-ESF---EVKQFHYTAWPDFGVPDHPNPIISFIRRVNNSTHtgPLVVHCSAGVGRSGTFIAIQSMMLMMETEG
...| ..... | ... .| . | | . |. |.| ||| . .. | .| . |.|||||||.||| .||. . . .|..
rfkikiknkelilnkkiskrtlevedstgkfatrtvthyqysewtdrgvPkshaelfdlmelvkksek..PivvhcsaGiGrsvafigteylareveadp
KVDVFNFVLDMRHKRNYMVQTEAQYMFVH-DSLVELI
.... . . ..|..| |||. | .. .. ||
tieltealkhlrehrwngvqtnsqlywmtlGtvyrli
|
|||||||||
subfamily_egg_pd | Subfamily egg | 1260-1497 | 1.3e-31 | 104.4 | In-house | 30-267 (307) | alignment | ||
Range on Protein: 1260-1497
Range on HMM: 30-267/307.0
LPHEASQQTCNIEKNRYGNINSFDETRVVLTKIPGIEGSDYINANYIDGYGSRDTYIACQGPLAETSPDFWRMIWEQKTSCIVMLTNCVEKgrPKCHQYW
. . . . | || | .. | .|| | | |.| ||...| ...| .| || .| |||||..... ||||| .| .|. ||
islttaasdnnlekarskrvhckdssrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvddfwrmvfqeevqyivmltsrkes..erceyyw
PQTGS--TTF--GELTVTI--IDQQVLAYYTIRTFKINNKDDESFEVKQFHYtAWPDFGVPDHPNPIIsfiRRVNNSTHtgPLVVHCSAGVGRSGTFIAI
|.. | . | | .. .|.. ... .|. ||| .. . . . . | .. |.. | .. | ||.. || ...|..||
pkaesdslvtvpGslrienlkvdskadplfrvtklklvGgddeerflehwqg.dvnnssdvysplrvl...rklrnlsk..pvvvqdilGvskaatlvai
QS--MMLMMETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLV
. . |. | | . | .| .|.. |.. .|.||. ..
eiallsllrGpitkslvlravvflrlrrrlsvesvllylfvyrlvl
|
|||||||||
subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 1561-1809 | 1.4e-31 | 104.2 | In-house | 49-298 (305) | alignment | ||
Range on Protein: 1561-1809
Range on HMM: 49-298/305.0
SASLPVNRAKNRYPDIlPYESYRVRLLMLPGvsGSDYINASYVDGYLR-CNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCGLVEDGKDQSVQYWPKD
| .. .|||| |. | . . .| | |||| | || . ..|| .|||| .|.|.|| |. ...| ||||| || || . ||||
nqsadiaitknryqdv.pcqdqsavkldkps..psdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkveqivmlcktvelgklkcaqywpaa
---QLTQYGDMFIETISETDTgFYVIREITITH---TKQGNEVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAHHlfgggPVVVHDSSSVGRSGTFC
.|. . . .| .| . . || || | |.. ......|.| . || . .... .. .. |.||| |. .||.||
qgeklelksgivvenvsgskp.merdaeiqitllnltysgdqkmsvrhlqwtewpdrgvppckltslellsairgskv.....pivvhcsagigrtgtiv
IINIVIERLKVEGMID-IFFTIHALRRKHPGIVANYDQFKFCYQTIVEYL-ESF-DKYA
|. ..|.. . . ..||| . . | |. | .. ...|. | . .|||
aieyilekiaenkpcppmpelvkalrdqrafsiqndvqylfihrvmlnyflekykekya
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 1258-1425 | 1.5e-31 | 104.3 | In-house | 21-191 (297) | alignment | ||
Range on Protein: 1258-1425
Range on HMM: 21-191/297.0
PSLPHEASQQTCNIEKNRYGNINSFDETRVVLTKipGIEGSDYINANYIDGYGS--RDTYIACQGPLAETSPDFWRMIWEQKTSCIVMLTNCVEKGRPKC
. .... . |||| .| ..|.||| | . .| ..|||||.|. || |||| .| |||....|| |||... | || ||
rgesfssakrnsslrknryrdilatddtrvkllr..viterdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrdkc
HQYWPQT--GSTTFGELTVTIIDQQVLAYYTIRTF--KINNKdDESFEVKQFHYTAWPDFGVPDHPNPIISFIR
|||.. . . |.. | . . . .. .. . .|| |. . .||| ||| . . |
apywpsvvqerlkagdvvveflsstsdefdrviltelqliyr.sesrvvrhvqflswpdhGvpsdledlvrfqa
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 1554-1713 | 4.9e-31 | 102.7 | In-house | 20-180 (297) | alignment | ||
Range on Protein: 1554-1713
Range on HMM: 20-180/297.0
AIPSQYISASLPVNRAKNRYPDILPYESYRVRLLMlpGVSGSDYINASYVDGY--LRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCGLVEDGKDQ
| . .. || . |||| ||| ... ||.|| .....||||| || ..|..|||||.||||||....|. | .|||.. | |||.|.
argesfssakrnsslrknryrdilatddtrvkllr..viterdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrdk
SVQYWPKDQ--LTQYGDMFIETISETDTGFYV--IREITITHTkqgNEVRNIKQFHYTDWSENKTP
. |||. . . ||. .| .|.| | . |... . .| | .. . | . |
capywpsvvqerlkagdvvveflsstsdefdrviltelqliyr...sesrvvrhvqflswpdhGvp
|
|||||||||
subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 1566-1803 | 3.8e-29 | 96.6 | In-house | 42-272 (288) | alignment | ||
Range on Protein: 1566-1803
Range on HMM: 42-272/288.0
VNRAKNRYPDILPYESYRVRLLmlpgVSGSDYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCGLVEDGKDQSVQYWPK--DQLTQ
| ...|| .. . ||.| ||.| | ...| .| || |.. .|.|. | | ||||| |.| ||..| .|.| . ..
anptrdryenlprcditrvkls....ddpdfyiaanvvssakykrrlicaqaPlngtieelWkmllesdveyivmlcellekGkeksaeyfPsklGekar
YGDMFIETISETdTGFY-VIREITITHTKQGNEVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAHHlfgggPVVVHDSSSVGRSGTFCIINIVIERL
.| . . . .. ... .. .|.|.| .|. |. .| .. | . . .. ... .. |.||| | |||.||. .| |..| |
igrlctvvkkkr.adidklvkvsllriskegeekvivkilhlleWdddgvPenylsplrllevlkslqk.....PivvhssaGvGrtgtlililialesl
KVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYLE
... . | .. || .. . |. . .. . |.|
rlddflgirsllaklreerfkaiqtemqylyvhrcvleell
|
|||||||||
subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 1568-1803 | 4e-29 | 96.3 | In-house | 49-288 (305) | alignment | ||
Range on Protein: 1568-1803
Range on HMM: 49-288/305.0
RAKNRYPDILPYESYRVRLlmlPGVSGSDYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCGLVEDGKDQSVQYWPKDQ---LT-Q
. |||| |. . ||.| | .|| | || ..|| || || .| ||| | ....| || ||| |.| | . ..|.. .. |. .
agknrykdvgcldnnrvkl...egpwpheyihanyvstptnpkrfictqaplektcadfwymclqdkveaifmlcnllekgakkcleyfaskdkdvlefe
YGDM--FIETISETDTGFY-----VIREITITHTKQGNEVRNIKQFHYTDWSENKTPPTTgalMDMIVLVQKAHHLfgGGPVVVHDSSSVGRSGTFCIIN
.. . | . | ...| .. |...| ....|. || . |.. . .. |..|| . ||.||| |. .||.|. ...
ekgqkisvkfessvtlkfrkdakakvtetvlviegpgekarkvthyhwidwpdrgvpaad...lailellekarps..kgpivvhcsagigrtgsvvmle
IVIERLKVEGMIDIFF-TIHALRRKHPGIVANYDQFKFCYQTIVEYLE
....| .|. . .| . . .|. | .| |..|..
yildqllagqiiedtdkilqkireqrnnsiqtdaqylfvhqvilnyfr
|
|||||||||
subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 1563-1765 | 5.6e-29 | 95.7 | In-house | 33-230 (281) | alignment | ||
Range on Protein: 1563-1765
Range on HMM: 33-230/281.0
SLPVNRAKNRYPDILPYESYRVRLLM-LPGVSGSDYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCGLVEDGKDQSVQYWPKDQL
||| |||| .| . ||.| . .| .||| | |. . .|.|||| .| |||||||. .|||||| ..| ... .|.|..
nqpvnnkknrylnipcldisrvqlkvkmpnknstdyihanyirspflkrgyiltqgpkketradfwrmiwqenttaivmlcqfletnrekcaeyfprnah
--TQYGDMFIETISETDTGFYVIREITITHtkqGNEVRNIKQFHYTDWSENKTPPTTGALMDMIvLVQKAHhlfgGGPVVVHDSSSVGRSGTFCIINIVI
|. . .. | | . ... | | | .. . .| . . | .. .. .. .|. | |.| |. ||||||. ..| .
cclqfdklsvsyedstvnkslvttrlnlsy...egetrlithwlwkewpdwqvpessevmlkil.rkirar....stppvihcsagvgrsgtlmaveial
ERLKVE
. ..
qsihsh
|
|||||||||
0044763 | (Phosphotyrosine protein) phosphatases II | 1578-1799 | 1.2e-28 | 95.4 | In-house | 1-168 (178) | alignment | ||
Range on Protein: 1578-1799
Range on HMM: 1-168/178.0
PYESYRVRLLMLPGVSGSDYINASYVDGYlrcnQFIMTQGPlsntvDDFWRMIWEHRVSAIVMLCGLVEDGKDQSVQYWPKDQLtqygdmfietisetdt
|.. .|| | .|.|. .|||||||..... ......| |......|. ...||.|.. .| |. .. .|||..
pldrtrvllsnleglersdyinaseilpg....lylgslpp.....addlellkelgithivnlteelelgflkcdpywpeeag................
gfyvireitithtkqgnevrniKQFHYTDWSENKTPPTTGALMDMIVLVQKAHHlFGGGPVVVHDSSSVGRSGTFCIINIVIERlkveGMiDIFFTIHAL
|.... .. ...|. . ..... ....|.. ||||.|| | ||||||.... ..... |. ... |. .
......................iqylhipipDhgvpdllehflefvefieeald.ekggpvlVHCsaGvgRsgtlvaaylmkkl....gl.sleeaielv
RRKHPgIVANYDQFKFCYQTIV
|.. | || | .| ...|.
rerRp.ivpnpgqlrqLyefel
|
|||||||||
subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 1541-1781 | 1.1e-27 | 91.5 | In-house | 29-269 (310) | alignment | ||
Range on Protein: 1541-1781
Range on HMM: 29-269/310.0
LPKQFEKLNSIDvaiPSQYISASLPVNRAKNRYPDILPYESYRVRLLMlPGVSGSDYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVM
| ||. ||.. . | . . |||| |.. .. ||.| . ||| | || . || .|||| |. ||||||.. | .|..
lvkqyrkldakq...dssltyeaykkymhknrysdvvcldtsrvklki.dksryedyihanyvktnylrstficsqgplqhtiidfwrmifqeraesill
LCGLVEDGKDQSVQYWPKDQLTQ-YGDMFIETISETDTGFYVIrEITITHTKQ-------GNEVRN--IKQFHYTDWSENKTPPTTGALMDMIVLVQKAH
|| .|.|. ..| ||| .|. || . . .||. | . ....| . .... .. .. .| . | . .| | |
lckvgeegrpkcvgywpslgvtetygcirvtnlsesseefeic.nlavtfvpdnvpvdeqpanlkelrvslikwpnwpdrgvpdekchtvpqrllaqvrh
hlfggGPVVVHDSSSVGRSGTFCIINIVIERLKVEGMIDIFFTIHALRRKH
||.||| |. ..| .. . ... |..|. .|. . |....
.....gpcvvhcsagkdrlyvvvalklkidkldrglkvdaeevktellksr
|
|||||||||
0051082 | (Phosphotyrosine protein) phosphatases II | 1595-1798 | 3.7e-27 | 90.2 | In-house | 3-149 (151) | alignment | ||
Range on Protein: 1595-1798
Range on HMM: 3-149/151.0
SDYINASYVDGYlrcnqFIMTQGPLSntvdDFWRMIWEHRVSAIVMLCGLVEDGkdQSVQYWPKDQltqygdmfietisetdtgfyvireitithtkqgn
|||||.|||.|. .. ..|||. ||.....|. ...||.|....| | .|.|. .
sdyinfsyvtgg.....lyrsggpla....dflellkelgiktivnlrseeerg..ycpeylpelg..................................
evRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKahhlFGGGPVVVHDSSSVGRSGTFCIINIVIERlkvegmIDIFFTIHALRRKHPGIVANYDQFKFC
.........||.. ..| .. |..... |... ..|||.|| |. .||.||.... ..... .... ... .|.|.||.| .|| |.
..ievlhipildwpdpglplsfdavleflellld....kkngpvlvHCsaGkgRTGtlvalylmllg......vsleealeeyrlkrpgvvqpnqqflfq
YQTI
.. .
lfal
|
|||||||||
0048076 | (Phosphotyrosine protein) phosphatases II | 1374-1497 | 2e-26 | 87.8 | In-house | 19-140 (145) | alignment | ||
Range on Protein: 1374-1497
Range on HMM: 19-140/145.0
IIDQQVLAYYTIRT---FkINNKDDESFEVKQFHYTAWPDFGVPDHPNPIISFIRRVNNSTH-TGPLVVHCSAGVGRSGTFIAIQSMMLmmetEGkVDVF
.| . |. . |.| . ....... .. |..|. |||.|||| .. ...|.. ... || .|||||||||.||..|. |.| .| |...
aldlellkdlgittvlnl.tselellerlgiqylylpwpDhgvpdllellleflefieealkeggpvlVHCsaGvgRtgtlvaaylmll....lg.vsle
NFVLDMRHKRNYMVQTEAQYMFVHDSLV
. . .| .| ..|... |. |... .
ealelvrsqrpgavpnpgqlrflyefel
|
|||||||||
subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 1273-1501 | 3e-26 | 86.9 | In-house | 46-277 (312) | alignment | ||
Range on Protein: 1273-1501
Range on HMM: 46-277/312.0
KNRYGNINSFDETRVVLTkipGIEgSDYINANYIDGYGSRDTYIACQGPLAETSPDFWRMIWEQKTSCIVMLTNCVEKGRPKCHQYWPQTGS-------T
||| ||. .| | |. | | || ||.. . ....|||| .|. ||.. ...|..|. || | || .| . .
lnrypniqcwdrgrftla...gde.nfyihanfvkictkperfvctqgplentcthfwqlalslgstsiillcgfvedgsekcakyisdivgfvdledhr
TFGELTVT-IIDQQVLAYYTIRTFKINNKDDE-SFEVKQFHYTAWPDFGVPDHPNPIISFIRRVNNSthTGPLVVHCSAGVGRSGTFIAIQSMMLMMETE
. | | . | | .|. | .... ...||| |.|| . .. |.. |.. ||||||||.||.. |.||. .
vyteycteieiggkskdkithrvlkvvvkatgqesklnhyqwaswpdhgmpdscdtalrllsavkkd..kkpviahcsagvgrtgtlaliesmiaalrhp
GKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELIK
| .| . . .|. | |.. .||... ...|..
rkqnvkdsfvllrkdrarsvrvfpqyvyalrcvlefly
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 1396-1505 | 1.4e-25 | 84.5 | In-house | 87-199 (440) | alignment | ||
Range on Protein: 1396-1505
Range on HMM: 87-199/440.0
ESFEVKQFHYTAWPDFGVPDHPNPIISFIRRVNNST---HTGPLVVHCSAGVGRSGTFIAIQSMMLMMETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFV
|| .||.|| .||| ||| |.. .|. ||.| |||.||||||.||.| ||..|.. . ..|.|.|. || .| |||| || ||
esrtlkqyhyqgwpdkgvpkfagpvlkmiqdvnesqekagngpllvhcsagagrtgviiavdsilreakrsdqidifsfinsmrnnrpqmvqtpeqyafv
HDSLVELIKVGNS
|....| . .|..
heavlegllcgdt
|
|||||||||
0048179 | (Phosphotyrosine protein) phosphatases II | 1394-1494 | 3.8e-25 | 83.7 | In-house | 43-139 (144) | alignment | ||
Range on Protein: 1394-1494
Range on HMM: 43-139/144.0
DDESFEVKQFHYTAWPDFGVPDHPNPIISFIRRVNNS-THTGPLVVHCSAGVGRSGTFIAIQSMMlmmeTEGkVDVFNFVLDMRHKRNYMVQTEAQYMFV
... .|. |.... |||.||||... ...|.. ... . || .|||||||||.||..|. |. ..| ..... . .| .| ..|... |..|.
efleregiqylhlpwpDhgvpdllellleflefieealeeggpvlVHCsaGvgRtgtlvaaylmk....klg.lsleealalvrsrrpgavpnpgqlrfL
HD
..
le
|
|||||||||
subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 1280-1514 | 4.9e-25 | 83.2 | In-house | 28-272 (290) | alignment | ||
Range on Protein: 1280-1514
Range on HMM: 28-272/290.0
NSFDETRVVLTKIPGIEGSDYINANYIDgYGSRDTYIACQGPLAET-------SPDFWRMIWEQKTSCIVMLTNCVEKGRP----KCHQYWPQTG--STT
. .||||| .||| ||.. . . |. | |.... .|| |. . | .||| . || . | .| |.. . .
pLveatrvvLkgygkrfnddyiHAnrvt.cpnglrliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCakYvpesvgeelk
FGELTVTIIDQQVLAYYTIRTFKINNKDDESFEVKQFHYTAWPDFGVPDHPNPIISFIRRVNnsTHTGPLVVHCSAGVGRSGTFIAIQSMM-LMMETEGK
|. ||| .. .|. .. |.| | |. . | . |.... ..| |. |. ... | .||| |. || .. ||. . ...||.|.
fkgltvkCkskekeddvetRelvvkfddeeeftvtHsllkgWnklnvqedtktllsliqkvk..asktpvivHcvdGiSrsAalaaiilgyQkiaetsgs
VDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVeLIKVGNSEQTVQNFPK
| . . . ..|..|. ..... .. || .| | . .|.... ..
vkledvlkalrkqralaitsalelafvdagiv.llaievldqfaeeete
|
|||||||||
subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 1318-1492 | 4.3e-24 | 79.5 | In-house | 96-280 (302) | alignment | ||
Range on Protein: 1318-1492
Range on HMM: 96-280/302.0
CQGPLAETSPDFWRMIWEQKTSCIVMLTNCVEKGRPKCHQYWPQ--TGSTTFGELTVTII----------DQQVLAYYTIRTFKINNKDDESFEVKQFHY
| .| .| .| . ... .| |.. ||.. || .|. . | .||. ||. . |.. . ||. . |.. . |. ...
pivpkkstlekhwalieqynvaivvqlcsfvedeekkcaeyysdkvggelkfgrytvktvsvktdleeftdkksfklytveiknekkkkkvkktvdilaf
TAWPDFGVPDHPNPIISFIRRVNnsTHTGPLVVHCSAGVGRSGTFIAIQSMMLMMETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFV
.|||| | |..... . .. . .. ..|||||||||.||..||. . . .. |. . || .|. | ||.| | ...
sawpdhGapkeaytaldilkfce..sykknvlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqdeqqliyl
|
|||||||||
subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 1568-1780 | 5.8e-24 | 79.4 | In-house | 51-259 (301) | alignment | ||
Range on Protein: 1568-1780
Range on HMM: 51-259/301.0
RAKNRYPDIlPYESYRVRLLMLPGVSgsDYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCGLVEDGKDQSVQYWPKDQLTQ--YG
. |.||| . | . .. | | | ... . ..|| |||||.|| .||| |. . | ||||. ||. ... .| | . . |
kdkhryptv.PckPstavevivdGkr..vPihanwiptsGhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkisekldig
DMFIETISETD--TGFYVIREITITHTKQGNEVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAHHlfgggPVVVHDSSSVGRSGTFCIINIVIERLK
|.. .. . |.. .. . . . | . . |..|... .| . |.|.. ||.|... |.||| |. .||| .| ... ...
rfkikiknkelilnkkiskrtlevedstgkfatrtvthyqysewtdrgvPkshaelfdlmelvkksek.....PivvhcsaGiGrsvafigteylareve
VEGMIDIFFTIHALRRK
. |.. ... || .
adptieltealkhlreh
|
|||||||||
subfamily_egg_pd | Subfamily egg | 1566-1799 | 6.4e-24 | 79.2 | In-house | 39-267 (307) | alignment | ||
Range on Protein: 1566-1799
Range on HMM: 39-267/307.0
VNRAKNRYPDILPYESYRVRLLMLPGVSGSDYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCGLVEDgkDQSVQYWPKDQ---LT
|. | | . . .| ||.| . | |.| | .|.| |.||..| || |||||||||... .| |||| .| .. |||| . |
nnlekarskrvhckdssrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvddfwrmvfqeevqyivmltsrkes..erceyywpkaesdslv
Q-YGDMFIETISETDTGFYVIreiTITHTKQ-GNEvrnIKQFHYTDWSENKTppTTGALMDMIVLVQKAHHLfgGGPVVVHDSSSVGRSGTFCIINIVIE
| . ||.. .. . ..|. | | . .. . | . .. . . ...|. .| ||||.| | ...|. |.| .
tvpGslrienlkvdskadplf...rvtklklvGgd...deerflehwqgdvn..nssdvysplrvlrklrnl..skpvvvqdilGvskaatlvaieiall
RLkVEGMI---DIFFTIHALRRKHPGIVANYDQFKFCYQTIV
| . | | . .. ||.. . | .. | |. ..
sl.lrGpitkslvlravvflrlrrrlsvesvllylfvyrlvl
|
|||||||||
subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 1327-1510 | 6.6e-24 | 79.4 | In-house | 42-232 (255) | alignment | ||
Range on Protein: 1327-1510
Range on HMM: 42-232/255.0
PDFWRMIWEQKTSCIVMLTNCVEKGRPKCHQYWPQ--TGSTTFGELTVTIIDqqVLAYYTIRTFKINN---KDDESFEVKQFHYTAWPDFGVPDHPNPII
|...| .||. .|||.. |.|. ||..|.| . . ...|| . | .|| .| . . .|| ..|. |.. |. .. |
dkfyqtivqtktevvvmlcdfaeegvekcssyfplekdeklkladvnvtttk..ssadvvlrtleitstlgekkkthtvkhysykGWieknaPelareil
SFIRRVNNSthtGPLVVHCSAGVGRSGTFIAI----QSMMLMMETE--GKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELI-KVGNSEQTVQ
.. | .| ..|||||.|.||| .|. . | |.. ..| ...| ... ..|.||. ..| | | ...|. |. |. |
nilkvvrds...ksvvvhCstGiGrsaafvlaelvyqkmirsldttetveldylslleelrskrkraihtPlqlafsilmvldlvfpkgeleakyq
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 1565-1729 | 2.4e-23 | 77.3 | In-house | 25-193 (319) | alignment | ||
Range on Protein: 1565-1729
Range on HMM: 25-193/319.0
P-VNRAKNRYPDILPYESYRVRLLMLPGVSGSDYINASYVDGYLRC-NQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCGLVEDGKDQSVQYWPK----
| . |.|. ...| || | . . |..|||| || . |..| .| .| .. ||||..|| . || |. | | | .. .|.|
PvtskdksrvinvvPlPetrvvlqrigdddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlselGikvcaeylPtketl
DQLTQYGDMFIETISETDTGFYVIREITITHTkQGNEVRNIKQFHYtDWSENKTPPTTGALMDMIVLVQKA
|. |||. . |.| . . . ...| |.. . | .| | . | ||. |.. |...
dntslyGdilvtlkgrevkdryaistlllkrv.dkeesrelthywy.kwleaevPaeeaaliamllevrss
|
|||||||||
subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 1555-1802 | 9.4e-23 | 75.6 | In-house | 23-270 (285) | alignment | ||
Range on Protein: 1555-1802
Range on HMM: 23-270/285.0
IPSQYISASLPVNRAKNRYPDILPYESYRVRLLmlpgVSGSDYINASYVDGYLR-CNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCGLVEDGKDQSV
.| . .. | ||| |. | || | ||| ||.. . . .| ||||| .|. |||.||.. ... ..||| |.| | ..
mppnctytayeanpdlnryadvrcieetrvvlk....nhdrdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekca
QYWPKD--QLTQYGDMFI---ETISETDTGfYVIREITITHTKQG-NEVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAHHlfGGGPVVVHDSSSVG
|.|. .. ..| | | |. .| .. .|.. |.. .| ... . | .. .| . .... |.| |..|| |. ||
lyypeklgevvkfgkyeitlteckeeaiag.tilnaltvintedasseplymnhvqvpwwpdqlapedarpmielykwvkkvnp..kekpicvhcsagvg
RSGTFCIINIVIERLKVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYL
|. || |. |. . |... .. .| . | .. || | | ..||.
rtatfvgidyatirimenpniemldivremramrfqavqshmqflflyvvlmeyf
|
|||||||||
PTPc_DSPc_SM00012 | 1699-1799 | 1.5e-22 | 75.2 | In-house | 2-104 (105) | alignment | |||
Range on Protein: 1699-1799
Range on HMM: 2-104/105.0
IKQFHYTDWSENKTPPTTGALMDMIVLVQKAHHLFG-GGPVVVHDSSSVGRSGTFCIINIVIERLKVE-GMIDIFFTIHALRRKHPGIVANYDQFKFCYQ
.|..|||.|.. ..| .. ...... |.| .. . ..|||||.| |||.|||. . |....|. | . .||| ....||.. || | ...|. |.|.
vkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylflyr
TIV
.
all
|
|||||||||
subfamily_Sponge-PTP-7_pd | Subfamily Sponge-PTP-7 | 1436-1503 | 2.1e-21 | 70.1 | In-house | 1-68 (69) | alignment | ||
Range on Protein: 1436-1503
Range on HMM: 1-68/69.0
LVVHCSAGVGRSGTFIAIQSMMLMMETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELIKVG
.|||||.| ||.|||||| | . .| ||.|| | || | || | .|.|.||.||| .|.|
mvvhcssgtgrtgtfiaimvemarikseklvdifnnvqymrkcrpmmvmneieyifihdalvealklG
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 1568-1662 | 2.6e-21 | 70.8 | In-house | 48-156 (350) | alignment | ||
Range on Protein: 1568-1662
Range on HMM: 48-156/350.0
RAKNRYPDILPYESYRVRLL--------MLPGVSGSDYINASYVDGY----LRCNQ--FIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCGLVEDGKDQSV
||||| .||||| ||.| . .|..|||||.|. . .| ||.|| .|||||...| . | |..| .|| . ..
faknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcy
QYWPKDQLT
.||.. .
rYWqegsyd
|
|||||||||
subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 1265-1500 | 3.1e-21 | 70.3 | In-house | 42-279 (303) | alignment | ||
Range on Protein: 1265-1500
Range on HMM: 42-279/303.0
SQQTCNIEKNRYGNINSFDETRVVLTKipgiegSDYINANYIDGYgSRDTYIACQGPLAETSPDFWRMIWEQKTSCIVMLTNCVEKGRPKCHQYWPQTGS
| |..|||. .. .| ..| |. | || |.|.. |. | | ||. |. |||.|| ||| |...| | . . .|.
nqfvknmdknrfvdvicldhskvklsd......ssyihasyleld.sskkailtqlplshtaadfwqmiieqkvkcvlllltdseydklggdsvfprnqd
-TTFGELTVTIIDQ---QVLAYYTIRTFKINNKDDESFeVKQFHYTAWPDFGVPDHPNP-IISFIRRV----NNSTHTGPLVVHCSAGVGRSGTFIAIQS
| | .. . . .. .... . | | || .. || ||| .| . .| .. | .. . ... | | .|.||.||| ...
flkfeersirvgefkrvelgdgwvlkvlsvsngdyksf.lhvhhykawphnsipsdgspkfvkqiwqlqsvlrkysdstptvymslsgcgragtfalfet
MMLMMETE-GKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELI
| . .| .|. . . .| | . || .|. .|. | | .
ahlslhseqasldlvkclenvrngrlhavqnlsqfsvvytllaehv
|
|||||||||
subfamily_Sponge-PTP7_pd | Subfamily Sponge-PTP7 | 1437-1503 | 3.6e-21 | 69.3 | In-house | 1-67 (69) | alignment | ||
Range on Protein: 1437-1503
Range on HMM: 1-67/69.0
VVHCSAGVGRSGTFIAIQSMMLMMETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELIKVG
|||||.| ||.|||||| | . .| ||.|| | || | || | .|||.||.||| .|.|
vvhcssGtGrtGtfiaimvemarikseklvdifnnvqymrkcrpmmvmneneymfihdalvealklG
|
|||||||||
subfamily_hpo-7_pd | Subfamily hpo-7 | 1322-1501 | 3.9e-21 | 70.1 | In-house | 43-228 (263) | alignment | ||
Range on Protein: 1322-1501
Range on HMM: 43-228/263.0
LAETSPDFWRMIWEQKTSCIVMLTNCVEKGRPKCHQYWPQ--TGSTTFGELTVTIIDQQVlaYYTIRTFKINN---KDDESFEVKQFHYTAWPDFGVPDH
| .| . |...| .||. .|||.. |.|. || .|.| . . ...|. . | ..| .. . . . .||.. |. |.. |
lvqtidkfyqtivqtktevvvmLcDfneegvekcssyfPlekdekqklanvnvcttkvqs..dvllktlellstlgeKkkthtvkhysykgWiekndpel
PNPIISFIRRVNNSthtGPLVVHCSAGVGRSGTFIA----IQSMMLMMETE--GKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELIK
.. |. .. . || .||||||.|.||| | | |.. ..| ...| ... ..|..|. ..| | | .....
areilnilkvarns...kslvvhcstGiGrsaafsvaElvyqkmirsldttstveldylsLleelrssrkraihtPmqLafsilmvLdfvl
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 1269-1363 | 1.4e-20 | 68.3 | In-house | 46-154 (350) | alignment | ||
Range on Protein: 1269-1363
Range on HMM: 46-154/350.0
CNIEKNRYGNINSFDETRVVLTKI--------PGIEGSDYINANYIDGY------GSRDTYIACQGPLAETSPDFWRMIWEQKTSCIVMLTNCVEKGRPK
|||| || .. .|| | | ....|||||||. . ||| |.|| .| ||...| . | |..||. || .. |
elfaknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlek
CHQYWPQTG
|..||.. .
cyrYWqegs
|
|||||||||
subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 1611-1796 | 9.2e-20 | 65.7 | In-house | 6-198 (199) | alignment | ||
Range on Protein: 1611-1796
Range on HMM: 6-198/199.0
QFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCGLVEDGKDQSVQYWPKDQ--LTQYGDMFIETISETDTGFYVIREITITH-TKQGNEVRNIKQFHYTDW
..| || || .|. |||.|.|| |||. . . . ||| . ..|| . . | . | |.| . .| | |.| .. .| |
ryiatqhplretmadfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqftsw
SENKTPpTTGALMDMIVL---VQKAHHLFGGGPVVVHDSSSVGRSGTFCIINIVIERLK--VEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQ
|. || .. ..| | | . ||.|| | | .| | ..| . . ..|.| . ||. ||.. ....| ||
kekttp.nvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiyq
|
|||||||||
subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 1611-1796 | 9.3e-20 | 65.6 | In-house | 5-197 (198) | alignment | ||
Range on Protein: 1611-1796
Range on HMM: 5-197/198.0
QFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCGLVEDGKDQSVQYWPKDQ--LTQYGDMFIETISETDTGFYVIREITITH-TKQGNEVRNIKQFHYTDW
..| || || .|. |||.|.|| |||. . . . ||| . ..|| . . | . | |.| . .| | |.| .. .| |
ryiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqftsw
SENKTPpTTGALMDMIVL---VQKAHHLFGGGPVVVHDSSSVGRSGTFCIINIVIERLK--VEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQ
|. || .. ..| | | . ||.|| | | .| | ..| . . ..|.| . ||. ||.. ....| ||
kekttp.nvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiyq
|
|||||||||
subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 1568-1808 | 1.4e-19 | 65.0 | In-house | 44-282 (312) | alignment | ||
Range on Protein: 1568-1808
Range on HMM: 44-282/312.0
RAKNRYPDILPYESYRVRLlmlPGvSGSDYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCGLVEDGKDQSVQYWPKD-QLTQYGD
. ||||.| .. | | | || | .| . ..|. ||||| ||. ||.. ..|..|||.|||| .....| . . |
kdlnrypniqcwdrgrftl...ag.denfyihanfvkictkperfvctqgplentcthfwqlalslgstsiillcgfvedgsekcakyisdivgfvdled
--MFIETISETDTGFYVIREITITH-----TKQGNEvRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAHHlfgggPVVVHDSSSVGRSGTFCIINIVI
.. | .| . | || |.| ..... .. | . | . . . .. |.| .. ||. | |. |||.||...|. .|
hrvyteycteieiggkskdkithrvlkvvvkatgqe.sklnhyqwaswpdhgmpdscdtalrllsavkkdkk.....pviahcsagvgrtgtlaliesmi
ERLKVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYLESFDKY
|. .. . ||. | . |. .. ....|.| | |
aalrhprkqnvkdsfvllrkdrarsvrvfpqyvyalrcvleflyskgly
|
|||||||||
subfamily_Sponge-PTP3_pd | Subfamily Sponge-PTP3 | 1225-1320 | 6e-19 | 62.0 | In-house | 4-95 (95) | alignment | ||
Range on Protein: 1225-1320
Range on HMM: 4-95/95.0
SISVSMFPDYVKRLHANTDHLFSEEYELITIKSPSlPHEASQQTCNIEKNRYGNINSFDETRVVLTKIpgiEGSDYINANYIDGYGSRDTYIACQG
| ||.| .| .|.|.|. | .|. |.. | . |. . .|| |||. || .| |||||| |||||| ..||| .. |||.||
pihvsvfhshvlemhsnsdqefdnefksismtsga.pytvgsseanipknrflnifpydatrvvlttk...rdsdyinacfvdgyarkncyiaaqg
|
|||||||||
subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 1554-1802 | 9.7e-18 | 58.8 | In-house | 34-279 (303) | alignment | ||
Range on Protein: 1554-1802
Range on HMM: 34-279/303.0
AIPSQYISASLPVNRAKNRYPDILPYESYRVRLlmlpgvSGSDYINASYVDGYlRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCGLVEDGKDQSV
.| . . | |||. |.. . .|.| | | || |||.. .. |.|| ||| | |||.|| | .| ...| | |
ylppsvsknqfvknmdknrfvdvicldhskvkl......sdssyihasyleld.sskkailtqlplshtaadfwqmiieqkvkcvlllltdseydklggd
QYWPKDQ-LTQYGDMFIETISETDTGFYVIREITITHTKQGNEVRNIKQFHYTDWSENKTPPT-TGALMDMIVLVQKAHHLFG-GGPVVVHDSSSVGRSG
.|..| . .. . .| . . . .|. .. || .| |. | . .. | .| . . | | | .||.|
svfprnqdflkfeersirvgefkrvelgdgwvlkvlsvsngdyksflhvhhykawphnsipsdgspkfvkqiwqlqsvlrkysdstptvymslsgcgrag
TFCIINIVIERLKVE-GMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYL
||.... |. | .|. . .| | | || . | . |..
tfalfetahlslhseqasldlvkclenvrngrlhavqnlsqfsvvytllaehv
|
|||||||||
subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 1269-1503 | 3.6e-17 | 56.7 | In-house | 50-288 (302) | alignment | ||
Range on Protein: 1269-1503
Range on HMM: 50-288/302.0
CNIEKNRYGNINSFDETRVVLTKIPgiegSDYINANYIDGYGSRDTYIACQGPLAETS---PDFWRMIWEQKTSCIVMLTNCVEKGRpKCHQYWPQTGS-
|..||. ... |...| |.. | .|.|| .. . . | | | ... .||||....| .|.| | . ....|..
knlkknqsedvpildsnlvkleaep....dsyvnaskvevPeltrsiilaQlpkvdsedsveeFWrmvfqekivsvvilvgeeelkk.tlselfpkksgd
-TTFGELTVTI-----IDQQVlAYYTIRTFkiNNKDDESFEVKQFHYTAWPDFGVPDHPNPIISFIRRV--NNSTHTGPLVVHCSAGVGRSGTFIAIQSM
...|.. | . .... |.| . . .| .. . | |.. ||.. . .| . | ... . ..|. |.|| |.|..
ykeygkmfvNnrkVekaeeek.tryviEvl..PegcsnsvlanvyvltnWkqkkvpvkyaeliktaakvfakkikadentvivSknGaGRagafltlava
MLMMETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELIKVG
. .... .. . . | .| .| .|.. ||.... .|. .||
veklqkgkepnikeivksiRsqRpravdslkQyvslyialllyikkk
|
|||||||||
subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 1313-1493 | 4.1e-17 | 57.0 | In-house | 4-196 (198) | alignment | ||
Range on Protein: 1313-1493
Range on HMM: 4-196/198.0
DTYIACQGPLAETSPDFWRMIWEQKTSCIVMLTNCVEKGRPKCHQYWPQTGST--TFGELTVTIIDQQVLAYYTIRTFKINNKD---DESFEVKQFHYTA
|||.| || || |||.|.|| . |||. . . ||| | |. .| |.|| . . ||| .. . |. . |. .. .|.
rryiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqfts
WPDFGVPDHPNpIISFI---RRVNN---STHTGPLVVHCSAGVGRSGTFIAIQSMMLMMET--EGKVDVFNFVLDMRHKRNYMVQTEAQYMFVH
| . |. .. |. | | . . |..|||| | | .| |.|.. . | ||.|. .| | .. . .| |..
wkekttpnval.fvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiy
|
|||||||||
subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 1313-1493 | 4.2e-17 | 57.0 | In-house | 5-197 (199) | alignment | ||
Range on Protein: 1313-1493
Range on HMM: 5-197/199.0
DTYIACQGPLAETSPDFWRMIWEQKTSCIVMLTNCVEKGRPKCHQYWPQTGST--TFGELTVTIIDQQVLAYYTIRTFKINNKD---DESFEVKQFHYTA
|||.| || || |||.|.|| . |||. . . ||| | |. .| |.|| . . ||| .. . |. . |. .. .|.
rryiatqhplretmadfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqfts
WPDFGVPDHPNpIISFI---RRVNN---STHTGPLVVHCSAGVGRSGTFIAIQSMMLMMET--EGKVDVFNFVLDMRHKRNYMVQTEAQYMFVH
| . |. .. |. | | . . |..|||| | | .| |.|.. . | ||.|. .| | .. . .| |..
wkekttpnval.fvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiy
|
|||||||||
subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 1556-1714 | 1.9e-16 | 54.4 | In-house | 85-237 (244) | alignment | ||
Range on Protein: 1556-1714
Range on HMM: 85-237/244.0
PSQYISASLPVNRAKNRYPDILPYESYRVRLLmlPGVSGSDYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLcGLVEDGkDqsvQY
|| | | | ||| ||.. || | | | |||||.| | ..|.|| ||..| |||.|. | | .|.| | ||. | .|
psvmkdafnpnnswknregaglpfdfnrvpls..kgsmgntyinasfvgclgrtaeyiltqhpladtsmdfwkmmlerhvnvlvvl.gsveee.d...ey
WPKD-QLTQYGDMFIETISETDTgFYVIREITITHTKQGNEVR-NIKQFHYTDWSENKTPP
|| | | . |... | | |. . . || . | ..| . | |
wpdseplewyeeditvtltdrde.fknikasnleiesdmneshqaltmfqisnwpsdgttp
|
|||||||||
subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 1595-1803 | 2.5e-16 | 54.7 | In-house | 46-260 (290) | alignment | ||
Range on Protein: 1595-1803
Range on HMM: 46-260/290.0
SDYINASYVDgYLRCNQFIMTQGPLSNT-------VDDFWRMIWEHRVSAIVMLCGLVEDGKDQSV----QYWPKD--QLTQYGDMFIETISETDTGFYV
.||| |..| . ..|.|| |. .. . .|| |. . .| .|||| | ...| .| |. . ..... .. |
ddyiHAnrvt.cpnglrliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCakYvpesvgeelkfkgltvkCkskekeddve
IREITITHTKQgnEVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAhhlfgGGPVVVHDSSSVGRSGTFCIINIVIERLK-VEGMIDIFFTIHALRRK
.||..... .. | .. . .|.. .....| |...| |.. . ||.||. . || .. |.. . .| . . ..|||..
tRelvvkfdde..eeftvtHsllkgWnklnvqedtktllsliqkvkas.....ktpvivHcvdGiSrsAalaaiilgyQkiaetsgsvkledvlkalrkq
HPGIVANYDQFKFCYQTIVEYLE
. .. .. | || ..
ralaitsalelafvdagivllai
|
|||||||||
subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 1620-1802 | 2.9e-16 | 54.3 | In-house | 38-221 (255) | alignment | ||
Range on Protein: 1620-1802
Range on HMM: 38-221/255.0
SNTVDDFWRMIWEHRVSAIVMLCGLVEDGKDQSVQYWP--KDQLTQYGDMFIETISETDTGFYVIREITITHTKqGNEVRNIKQFHYTDWSENKTPPTTG
| ||| |...| . . .|||| . |.|... .|.| ||. .. |. . | . .||| | .. . ...| ..|. | |...| .
sltvdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdeklkladvnvtttkssadvvlrtleitstlge.kkkthtvkhysykGWieknaPelar
ALMDMIVLVQKAHhlfgggPVVVHDSSSVGRSGTFCIINIVIE----RLKV--EGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYL
.. .. .|.... .|||| |. .||| .| ....| |. . .| .. || | .. . . |. |. ......
eilnilkvvrdsk......svvvhCstGiGrsaafvlaelvyqkmirsldttetveldylslleelrskrkraihtPlqlafsilmvldlv
|
|||||||||
0048076 | (Phosphotyrosine protein) phosphatases II | 1681-1800 | 4.8e-16 | 54.2 | In-house | 24-141 (145) | alignment | ||
Range on Protein: 1681-1800
Range on HMM: 24-141/145.0
VIREITITH-----TKQGNEVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAHHlfGGGPVVVHDSSSVGRSGTFCIINIVIErlkvEGmIDIFFTIH
... ||. . . ...|.. |..|..| . .|. . |.... ....|. ||||.|| | |||.||.... .... .| .... ...
llkdlgittvlnltselellerlgiqylylpwpDhgvpdllellleflefieealk..eggpvlVHCsaGvgRtgtlvaaylmll....lg.vsleeale
ALRRKHPGIVANYDQFKFCYQTIVE
.|...||.| | .|..|.|. . |
lvrsqrpgavpnpgqlrflyefele
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 1692-1804 | 7.8e-16 | 52.4 | In-house | 84-196 (440) | alignment | ||
Range on Protein: 1692-1804
Range on HMM: 84-196/440.0
QGNEVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAHHLFGGGPVVVHDSSSVGRSGTFCIINIVIERLKVEGMIDIFFTIHALRRKHPGIVANYDQF
.| | | .||.|| | .. | .| .. || |..... | ||..|| |...||.| .. .. | |||| | ..| ..| .| .|.
ngiesrtlkqyhyqgwpdkgvpkfagpvlkmiqdvnesqekagngpllvhcsagagrtgviiavdsilreakrsdqidifsfinsmrnnrpqmvqtpeqy
KFCYQTIVEYLES
| .....| | .
afvheavlegllc
|
|||||||||
subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 1564-1802 | 8.3e-16 | 52.3 | In-house | 48-285 (302) | alignment | ||
Range on Protein: 1564-1802
Range on HMM: 48-285/302.0
LPVNRAKNRYPDILPYESYRVRLLMLPgvsgSDYINASYVDGYLRCNQFIMTQGPLSNTV---DDFWRMIWEHRVSAIVMLCGLVEDGKdQSVQYWP--K
| .||. .|. ..| .|.| . | .|.||| |. .. |..| | .... ..||||...... .|.| | | | ...|
fkknlkknqsedvpildsnlvkleaep....dsyvnaskvevPeltrsiilaQlpkvdsedsveeFWrmvfqekivsvvilvgeeelkk.tlselfpkks
DQLTQYGDMFIET--ISETDTGF--YVIrEItITHTKQGNEVRNIKqfHYTDWSENKTPPTTGALMDMIVLVqKAHHLFGGGPVVVHDSSSVGRSGTFCI
.. ..||.||. . ..... ||| |. . . . |.. . | | ..| | ..|. .. | |.. . ..|. .|| |.|
gdykeygkmfvNnrkVekaeeektryvi.Ev.lPegcsnsvlanvy..vltnWkqkkvpvkyaeliktaakv.fakkikadentvivSknGaGRagaflt
INIVIERLKVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYL
...|.|. . | .....| . | .| ...|. . | ... |.
lavaveklqkgkepnikeivksiRsqRpravdslkQyvslyialllyi
|
|||||||||
subfamily_eak_pd | Subfamily eak | 1573-1802 | 2.4e-15 | 50.8 | In-house | 57-305 (332) | alignment | ||
Range on Protein: 1573-1802
Range on HMM: 57-305/332.0
YPDILPYESYRVRLLMlPGVSGSDYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCGLVEDGKDQSVQYWPKDQ--LTQYGDMFIE
.|.||. | ||| ||||| .. ...|.| . . | ||.|. | . |||.| || . ..| .|.|.. ..| . .|
vvkivpydrylvrlts.sqlnrlGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledvelkleksdkyfpdktreelkfGildve
TISETDTGFYVIREITIthtKQGNEVRNIKQFHYTDWSENKTPPTT------------GALmDMI--------VLVQKAHHLFGGGPVVVHDSSSVGRSG
. . . . | . . ..||| ... ... |.| ..| |.| .| ...| .| .. . |.|
rkefvkrniletrllel...skGnethrvlhykvfGwtettlpkyedflalrkvmkevGvl.llivmksallsstlkkyihtppsfapiiqsarGsaraG
TFCIINIVIERL--KVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYL
.| .|...|. . |.. . . | . | | | | |. ...||
vfvvidllirlidnkkknlysvedlilkvkskrihsvlvalqhsfiyeivldyl
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 1393-1499 | 1.2e-14 | 48.9 | In-house | 210-343 (350) | alignment | ||
Range on Protein: 1393-1499
Range on HMM: 210-343/350.0
KDDESFEVKQFHYTAWPDFGVPDHPNPIISFIR------------RVNNSTHTGPLVVHCSAGVGRSGTFIAIQSMML---MM----ETEGKVDV-----
. ..| |... |.| .. .|. |.. . .. .. |..||||||||| ||.... |.. .. . |.||
aasdPyvvyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktr
---FNFVLDMRHKRNYMVQTEAQYMFVHDSLVEL
. |. .|..| |||. |..|....| .
DlisiivnelrkqrismvqnldqfifiYeallfy
|
|||||||||
0048179 | (Phosphotyrosine protein) phosphatases II | 1682-1796 | 1.4e-14 | 49.5 | In-house | 33-139 (144) | alignment | ||
Range on Protein: 1682-1796
Range on HMM: 33-139/144.0
IREITITHTKQgNEVRNIKQFHYTDWSENKTPPTTGALMDMIVLVQKAHHlfGGGPVVVHDSSSVGRSGTFCIINIVIerlkVEGmIDIFFTIHALRRKH
. .| .. .. . |.. |.....| . .|. . | ... ....|. ||||.|| | |||.||.... ... ..| .... ... .|...
vinlteeyepe.fleregiqylhlpwpDhgvpdllellleflefieeale..eggpvlVHCsaGvgRtgtlvaaylmk....klg.lsleealalvrsrr
PGIVANYDQFKFCYQ
||.| | .|..|...
pgavpnpgqlrfLle
|
|||||||||
subfamily_eak_pd | Subfamily eak | 1262-1415 | 6.9e-14 | 46.0 | In-house | 44-196 (332) | alignment | ||
Range on Protein: 1262-1415
Range on HMM: 44-196/332.0
HEASQQTCNIEKNRYGnINSFDETRVVLTKIpGIEGSDYINANYIDGYGSRDTYIACQGPLAETSPDFWRMIWEQKTSCIVMLTNCVEKGRPKCHQYWPQ
. .... ....| .. | .| | || . |||| .. || . . . ||.|. |||. .||.| . ||.. | .|.|.
isetarleavnrnvvk.ivpydrylvrltss.qlnrlGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledvelkleksdkyfpd
TG--STTFGELTVTIIDQQVLAYYTIRTFKINnKDDESFEVKQFHYTAWPDFGVPD
. || | |. . . . | .... | .|. .|. ... | .. .|
ktreelkfGildverkefvkrniletrllels.kGnethrvlhykvfGwtettlpk
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 1429-1498 | 1.3e-13 | 45.3 | In-house | 243-313 (319) | alignment | ||
Range on Protein: 1429-1498
Range on HMM: 243-313/319.0
NSTHTGPLVVHCSAGVGRSGTFIAIQSMMLMMETE-GKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVE
. . |||||||| ||||.|. || . .|. ||. . | .|. | |.| || |.. | |
tresqGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefiykvlse
|
|||||||||
fn3 | Fibronectin type III domain | 864-949 | 1.5e-13 | 43.9 | Pfam-A | 2-85 (85) | alignment | ||
Range on Protein: 864-949
Range on HMM: 2-85/85.0
SPTIVSVFSTSNDSLSVSWSEIPpeETNGPIINYTIQFKINNNDN-QDMFQTVNTTQlQFTLTGLSGGTEYIIQVAGNTVIGHGPFS
.|. .|| .....||..|||. . . .||| .|..... .. . |.. .||. ..||||| |||| ..|. . | ||.|
aPenlsvsevtstsltlsWsppk..dgggpitgYeveyrekgggeewkeftvprttt.svtltgLkpgteYefrVqavngagegpeS
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 1307-1403 | 2.6e-13 | 44.1 | In-house | 230-323 (440) | alignment | ||
Range on Protein: 1307-1403
Range on HMM: 230-323/440.0
DGYGSRDTYIACQGPLAETSPDFWRMIWEQKTSCIVMLTNCVEKgrpKCHQYWP-QTGSTTFGELTVTIIDQQVLAYYTIRTFKINNKDdESFEVKQF
.|| ....|| | || | ||||.. . . | |.|| . .| | ||| .| | ||| .|| . . .||.... |. | |..||
egyskknafiatqmpldstvldfwrlvhdyristiimlnqlndk...tcsiywpvntrsvtfgpftvghkgsenmnrvkvrtlelkyke.evheirqf
|
|||||||||
subfamily_hpo-7_pd | Subfamily hpo-7 | 1619-1795 | 4.6e-13 | 43.7 | In-house | 43-220 (263) | alignment | ||
Range on Protein: 1619-1795
Range on HMM: 43-220/263.0
LSNTVDDFWRMIWEHRVSAIVMLCGLVEDGKDQSVQYWP--KDQLTQYGDMFIETISETDtgFYVIREITITHTKQ-GNEVRNIKQFHYTDWSENKTPPT
| .|.| |...| . . .|||| |.|... .|.| ||. .. .. . | . ... . .. | . .....|.. |. | |.. |
lvqtidkfyqtivqtktevvvmLcDfneegvekcssyfPlekdekqklanvnvcttkvqs..dvllktlellstlgeKkkthtvkhysykgWiekndpel
TGALMDMIVLVQKAHhlfgggPVVVHDSSSVGRSGTFCIINIVIE----RLKV--EGMIDIFFTIHALRRKHPGIVANYDQFKFCY
. . .. .... . ..||| |. .||| | ....| |. . .| .. || . .. . . |. |
areilnilkvarnsk......slvvhcstGiGrsaafsvaElvyqkmirsldttstveldylsLleelrssrkraihtPmqLafsi
|
|||||||||
subfamily_Sponge-PTP-4_pd | Subfamily Sponge-PTP-4 | 1577-1714 | 1.8e-12 | 41.7 | In-house | 3-128 (130) | alignment | ||
Range on Protein: 1577-1714
Range on HMM: 3-128/130.0
LPYESYRVRllmlpgvsGSDYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLcGLVEDGKdqsvQYWPKDQLT-QYGDMFIETISET
|..| |.. | .|||||.| | .....|| ||..| |||.|. | | .|.| | ||. .||| . | . | |...
lefevsrlq........gntyinasfvGllgrtaeylltqhpladtsmdfwkmmleryvnvlvvl.gsveeed....eywpdsePlewyeediivtltdr
DtGFYVIREITITHTKQGNE-VRNIKQFHYTDWSENKTPP
| .| |. . .. || . . |. ..| . | |
d.efknikasnleiesdlneshqaltmfqisnwpsdgttp
|
|||||||||
I-set | Immunoglobulin I-set domain | 376-447 | 1.9e-12 | 38.8 | Pfam-A | 3-74 (90) | alignment | ||
Range on Protein: 376-447
Range on HMM: 3-74/90.0
ISQIESETILPVGDSVVLSCTVTGSPAPMIRWYRDGSIMND--GIATATEGliIQSNLTLANLQQNQTGVYQCV
..|. ... .|.|| |.|||.|.| | ..|..||| .. . |. .. ||. | .....| |.|.
ftqklkdvevseGesvelectveGepepsvsWakdgselkssqrvkvtvee..aeytLtIsnvevsDeGkYtck
|
|||||||||
subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 1617-1793 | 4.8e-12 | 40.0 | In-house | 98-279 (302) | alignment | ||
Range on Protein: 1617-1793
Range on HMM: 98-279/302.0
GPLSNTVDDFWRMIWEHRVSAIVMLCGLVEDGKDQSVQYWPKD--QLTQYGDMFIETIS-------ETDTGFYVIREITITHTKQGNEV-RNIKQFHYTD
| .|.. .| .| ...|. .| ||..|||.. . .|. .. . ..| ..|.| || ... . |. .|. ..| . .. ....
vpkkstlekhwalieqynvaivvqlcsfvedeekkcaeyysdkvggelkfgrytvktvsvktdleeftdkksfklytveiknekkkkkvkktvdilafsa
WSENKTPPTTGALMDMIVLVQKAHHlfgggPVVVHDSSSVGRSGTFCIINIVIERLKVEGMIDIFFTIHALRRKHPGIVANYDQFKF
| . .| . . .|.. . . |.|| | |||.||. | |. . . . |. . .|. | | . .| .
wpdhGapkeaytaldilkfcesykk.....nvlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqdeqqliy
|
|||||||||
subfamily_Sponge-PTP3_pd | Subfamily Sponge-PTP3 | 1547-1617 | 3.1e-11 | 37.3 | In-house | 28-95 (95) | alignment | ||
Range on Protein: 1547-1617
Range on HMM: 28-95/95.0
KLNSIDVAIPSQYISASLPVNRAKNRYPDILPYESYRVRLLmlpGVSGSDYINASYVDGYLRCNQFIMTQG
...|| .. . | | | |||. .|.||.. || | |||||| .|||| | | .| .||
efksismtsgapytvgsseanipknrflnifpydatrvvlt...tkrdsdyinacfvdgyarkncyiaaqg
|
|||||||||
subfamily_Cele-PTP-12_pd | Subfamily Cele-PTP-12 | 1267-1353 | 3.7e-11 | 37.1 | In-house | 31-116 (332) | alignment | ||
Range on Protein: 1267-1353
Range on HMM: 31-116/332.0
QTCNIEKNRYGNINSFDETRVVLTKIPGieGSDYINANYIDGYGSRDTYIACQGPLAE-TSPDFWRMIWEQKTSCIVMLTNCVEKGRP
|.. || . || .|| |. | |. ||...||| . .|| .| |. . | ||||. |.| | |... . || .
flnnmdmnriphlycfdhsrvelapqdg..kddfynaswvdgyskksayifaqapfndhteyvfwrmvserkpsmilvfgdidekqkr
|
|||||||||
Ig_2 | Immunoglobulin domain | 381-452 | 1.1e-10 | 33.4 | Pfam-A | 7-68 (80) | alignment | ||
Range on Protein: 381-452
Range on HMM: 7-68/80.0
SETILPVGDSVVLSCTVTGSPAPMIRWYRDGSIMNDGiatategliiQSNLTLANLQQNQTGVYQCVFVSPG
. | .. |..|.| |...| |.| . ||.||.... . |..| . |.. .. |.|.|. ..
pptvvtegenvtLtCqapgnptpkvqwykdgeelsqs..........qnalfipnvsaedsGtYtCrasnse
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 1272-1361 | 1.1e-10 | 35.3 | In-house | 50-155 (349) | alignment | ||
Range on Protein: 1272-1361
Range on HMM: 50-155/349.0
EKNRYGNINSFDETRVVLTKIP--------------GIEGSDYINANYID--GYGSRDTYIACQGPLAETSPDFWRMIWEQKTSCIVMLTNCVEKGRPKC
|||| .| .. .||.| | . . |||||||. . ||| | || | ||...| .. .. |.. |.. ||
aknrykdilPyehsrvklkkslksskvikastsesdsgklddyinanylkltrisvekkyiatqaPlPstvddfykvillngvklvlsLnddkelslekc
HQYWPQ
..|| .
diywqe
|
|||||||||
subfamily_Sponge-PTP-7_pd | Subfamily Sponge-PTP-7 | 1739-1802 | 1.2e-10 | 35.6 | In-house | 2-65 (69) | alignment | ||
Range on Protein: 1739-1802
Range on HMM: 2-65/69.0
VVHDSSSVGRSGTFCIINIVIERLKVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYL
||| || ||.||| | . . |.| | ..||| . .|. | .| | .. | . ..|| |
vvhcssgtgrtgtfiaimvemarikseklvdifnnvqymrkcrpmmvmneieyifihdalveal
|
|||||||||
subfamily_Sponge-PTP7_pd | Subfamily Sponge-PTP7 | 1739-1802 | 1.3e-10 | 35.4 | In-house | 1-64 (69) | alignment | ||
Range on Protein: 1739-1802
Range on HMM: 1-64/69.0
VVHDSSSVGRSGTFCIINIVIERLKVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYL
||| || ||.||| | . . |.| | ..||| . .|. | .| | ... | ....|| |
vvhcssGtGrtGtfiaimvemarikseklvdifnnvqymrkcrpmmvmneneymfihdalveal
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 1224-1312 | 2.7e-10 | 34.2 | In-house | 4-89 (440) | alignment | ||
Range on Protein: 1224-1312
Range on HMM: 4-89/440.0
QSISVSMFPDYVKRlhANTDHLFSEEYELITIkSPSLPHEASQQTCNIEKNRYGNINSFDETRVVLTKIPGIEGSDYINANYIDGYGSR
. | |. | |||. | .|. |. . | | . . | |||| || ..| .||.| .. |. |||||| ||.| ||
rpiivadfadyvqn..nrrsrafedewsllps.glsqpsdiaslpnnkvknryrnilaydhsrvmleevkgvpdsdyinasyingiesr
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 1567-1659 | 3.1e-10 | 33.9 | In-house | 48-156 (349) | alignment | ||
Range on Protein: 1567-1659
Range on HMM: 48-156/349.0
NRAKNRYPDILPYESYRVRLLMLPGV--------------SGSDYINASYVDG--YLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCGLVEDGKD
||||| |||||| ||.| . ||||| |. . ...| || || |||||...| .| .. | | . .
lfaknrykdilPyehsrvklkkslksskvikastsesdsgklddyinanylkltrisvekkyiatqaPlPstvddfykvillngvklvlsLnddkelsle
QSVQYWPKD
. .|| .
kcdiywqel
|
|||||||||
subfamily_Sponge-PTP-4_pd | Subfamily Sponge-PTP-4 | 1295-1412 | 3.9e-10 | 34.1 | In-house | 10-125 (130) | alignment | ||
Range on Protein: 1295-1412
Range on HMM: 10-125/130.0
IEGSDYINANYIDGYGSRDTYIACQGPLAETSPDFWRMIWEQKTSCIVMLTNCVEKgrpkcHQYWPQTGSTTFG--ELTVTIIDQQVLAYYTIRTFKINN
..| .||||... | |. | |||.|| |||.|. |. .|.| |. .|||.. . ...||. |.. . ..|..
lqgntyinasfvGllgrtaeylltqhpladtsmdfwkmmleryvnvlvvlgsveee.....deywpdsePlewyeediivtltdrdefknikasnleies
KDDESFE-VKQFHYTAWPDFG
. || . . |. . || |
dlneshqaltmfqisnwpsdg
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 1735-1802 | 5.2e-10 | 33.5 | In-house | 247-315 (319) | alignment | ||
Range on Protein: 1735-1802
Range on HMM: 247-315/319.0
GGPVVVHDSSSVGRSGTFCIINIVIERLKVE-GMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYL
||.||| | |||.|. .| |..|. .|| ... .|| | . .|..| |... ||
qGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefiykvlseya
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 1604-1658 | 5.8e-10 | 33.1 | In-house | 230-281 (440) | alignment | ||
Range on Protein: 1604-1658
Range on HMM: 230-281/440.0
DGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLCGLVEdgKDQSVqYWPK
.|| . | || || || || ||||.. ..|.|.|.|| | . | |. |||
egyskknafiatqmpldstvldfwrlvhdyristiimlnqlnd..ktcsi.ywpv
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 1390-1501 | 1.1e-09 | 32.1 | In-house | 210-345 (349) | alignment | ||
Range on Protein: 1390-1501
Range on HMM: 210-345/349.0
INNKDDESFEVKQFHYTAWPDFGVPDHPNPIISFIR------------RVNNSTHTGPLVVHCSAGVGRSGTFIAIQSMMLMMET----EGKVDVFNFVL
|. . .. .|. |. . |.| .. | |. . .. .. .|.|||||| ||.|... ..... ..| |... .
illavekPyellqlqvknwldlslllnPisilqalevkndliddlfarlyldtdqlstllvhcsaGcGrtGvlvtldlllsileplqnesnkiklqallk
D--------MRHKRNYMVQTEAQYMFVHDSLVELIK
| .| .| ||| ||.......|.. ..
DlisiivnelrkqrismvqnlaqfiaiyealLkyfa
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 1434-1498 | 1.1e-09 | 32.6 | In-house | 229-293 (297) | alignment | ||
Range on Protein: 1434-1498
Range on HMM: 229-293/297.0
GPLVVHCSAGVGRSGTFIAIQSMMLMMETEGKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVE
.|.||||||||||| . . .. .. . || .. .|..| .||| |. ...| ..
ayllvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqtleqfellydavlk
|
|||||||||
subfamily_PTPDC1_pd | Subfamily PTPDC1 | 1403-1495 | 1.3e-09 | 32.7 | In-house | 85-171 (182) | alignment | ||
Range on Protein: 1403-1495
Range on HMM: 85-171/182.0
FHYTAWPDFGVPDhPNPIISFIRRVNNSTHTGPLVVHCSAGVGRSGTFIAIqsmMLMMETegKVDVFNFVLDMRHKRNYMVQTEAQYMFVHDS
.. .|.|.||. . |. .. |. . . | . ||| || || | || .|. . ... . . .|.|| .|| | .|..
vynfgwkDygvas.leriLdivkvvafalqegkvavhChaGlGrtGvliac...ylvyak..rltaekaiklvrskrpksiqtreqvelvkef
|
|||||||||
subfamily_Cele-PTP-12_pd | Subfamily Cele-PTP-12 | 1566-1649 | 2.8e-09 | 30.9 | In-house | 33-115 (332) | alignment | ||
Range on Protein: 1566-1649
Range on HMM: 33-115/332.0
VNRAKNRYPDILPYESYRVRLLmlPGVSGSDYINASYVDGYLRCNQFIMTQGPLSNTVD-DFWRMIWEHRVSAIVMLCGLVEDGK
| || | . .. || | | |. |||.|||| . . .|..| |. . . ||||. |.. | |... . | |
nnmdmnriphlycfdhsrvela..pqdgkddfynaswvdgyskksayifaqapfndhteyvfwrmvserkpsmilvfgdidekqk
|
|||||||||
subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 1312-1413 | 5e-09 | 30.1 | In-house | 136-235 (244) | alignment | ||
Range on Protein: 1312-1413
Range on HMM: 136-235/244.0
RDTYIACQGPLAETSPDFWRMIWEQKTSCIVMLTNCVEKgrpkcHQYWPQTGSTTFGE--LTVTIIDQQVLAYYTIRTFKINNKDDESFE-VKQFHYTAW
|| | |||.|| |||.|. |.. .|.| |. .|||.. . | .|||. |.. . ..|. .|| . . | . |
taeyiltqhpladtsmdfwkmmlerhvnvlvvlgsveee.....deywpdseplewyeeditvtltdrdefknikasnleiesdmneshqaltmfqisnw
PDFGV
| |
psdgt
|
|||||||||
subfamily_Cele-PTP-5_pd | Subfamily Cele-PTP-5 | 1621-1802 | 5.1e-09 | 29.2 | In-house | 129-309 (346) | alignment | ||
Range on Protein: 1621-1802
Range on HMM: 129-309/346.0
NTVDDFWRMIWEHRVSAIVMLCgLVEDGKDQSVQYWP-KDQLTQY-GDMFIETISETDTGfyVIREITITHTKQGNEVRNIKQFH-YTDWSENKTPPTTG
|.||| ||.. .. . .. . |. . . .. || | |||. .| .| || .|| | | | .. | . || |
sfvedfwymiyqeqihlvylmv.pddklkntttslfndenggyqytgkmfinnrradvsg..dpkeytievlpegnsdsvicqvhhhapwkhlqqppktl
ALMDMIVLVQKAHHLFGGGPVVVhDSSSVGRSGTFCIINIVIERLKVEGMIDIFFTIHALRRKHPGIVANYDQFKFCYQTIVEYL
.. || . . | || ||. .| |..| .|. ....... || | . |. | ...|.
piikmihqflsekqvqnagvcvv.slfgcgracsfigalyainqlnngiepniceimknikqqrpggvesfaqyasiyaivfdyi
|
|||||||||
subfamily_Sponge-PTP-2_pd | Subfamily Sponge-PTP-2 | 1266-1418 | 5.5e-09 | 29.2 | In-house | 23-159 (169) | alignment | ||
Range on Protein: 1266-1418
Range on HMM: 23-159/169.0
QQTCNIEKNRYGNINSFDETRVVLTKIPGIEGSDYINAnyidgygsrdtyiacqgplaetspdfwRMIWEQKTSCIVMLTNCVEKGR--PKCHQYWPQtG
. ||| ||| . ||| | .. ||||||| ||||| .| ||.| .. .| |. .|
eltcnetknrpagplapshtrvklqrvmedlgsdyina...........................rmiwetnasvivvlgdtddknnfwpekedyqlh.p
STTFGEL-----TVT-----IIDQQVLAYYTIRTFKINNKDDESFEVKQFHYTAWPDFGVPDHPN
. .|| | . | . . . . .|| . ... .||..||. |||. |
avilgewytdslyvrtdkvhantsgveglfevsmvihsydddvteklsllhystwpqngvpqspv
|
|||||||||
subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 1268-1345 | 6.9e-09 | 29.7 | In-house | 35-117 (347) | alignment | ||
Range on Protein: 1268-1345
Range on HMM: 35-117/347.0
TCNIEKNRYGNINSFDETRVVLTKI-----PGIEGSDYINANYIDGYGSRDTYIACQGPLAETSPDFWRMIWEQKTSCIVMLT
...||| . . |.|||||. . . |||| .| .. || | || .| |||.|. | . .| .
ekslsknrskdvklidatrvvlspeksknsraddvetyinashikfdnaskeyiltqyplpdtvrdfwkmvsvtkvtqvvtif
|
|||||||||
subfamily_Sponge-PTP2_pd | Subfamily Sponge-PTP2 | 1266-1418 | 7.6e-09 | 28.6 | In-house | 22-158 (169) | alignment | ||
Range on Protein: 1266-1418
Range on HMM: 22-158/169.0
QQTCNIEKNRYGNINSFDETRVVLTKIPGIEGSDYINAnyidgygsrdtyiacqgplaetspdfwRMIWEQKTSCIVMLTNCVEKGR--PKCHQYWPQtG
. ||| ||| . ||| | .. ||||||| ||||| .| ||.| .. .| |. .|
eltcnetknrpagplapshtrvklqrvmedlgsdyina...........................rmiwetnasvivvlGdtddknnfwpekedyqlh.p
STTFGE-----LTVTIID-----QQVLAYYTIRTFKINNKDDESFEVKQFHYTAWPDFGVPDHPN
. .|| | | | . . . . . .|| . ... .||..||. |||. |
avilGewytdslyvrtdkvhpntsgveglfevslvihsydddvteqlsllhystwpqngvpqspv
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 1553-1605 | 8.2e-09 | 29.3 | In-house | 35-85 (440) | alignment | ||
Range on Protein: 1553-1605
Range on HMM: 35-85/440.0
VAIPSQyiSASLPVNRAKNRYPDILPYESYRVRLLMLPGVSGSDYINASYVDG
.. ||. |||| |. |||| .|| |. || | . || ||||||||..|
lsqpsd..iaslpnnkvknryrnilaydhsrvmleevkgvpdsdyinasying
|
|||||||||
subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 1267-1308 | 9.6e-09 | 29.2 | In-house | 36-76 (244) | alignment | ||
Range on Protein: 1267-1308
Range on HMM: 36-76/244.0
QTCNIEKNRYGNINSFDETRVVLTKIpGIEGSDYINANYIDG
..| |||| || ||||||.|. |||||||||||.|
lsanatknryinilpfdetrvilsss.kkegsdyinanyiqg
|
|||||||||
ig | Immunoglobulin domain | 388-447 | 1e-08 | 26.4 | Pfam-A | 1-63 (64) | alignment | ||
Range on Protein: 388-447
Range on HMM: 1-63/64.0
GDSVVLSCTV-TGSPAPMIRWYRDGSIMNDGIATATEG---LIIQsNLTLANLQQNQTGVYQCV
|.|| |.|.| .|.| . . ||..|. .... | . ... ||. |.... |.| ||
GssvtLtCsvssgppstdvsWykegkgleesqktgvvenrvsaqe.vLtinnvtkedsGtYtCv
|
|||||||||
0038934 | (Phosphotyrosine protein) phosphatases II | 1402-1453 | 1.8e-08 | 29.8 | In-house | 81-135 (194) | alignment | ||
Range on Protein: 1402-1453
Range on HMM: 81-135/194.0
QFHYTAWPDFGVPDHPNPIISFIRRVNN---STHTGPLVVHCSAGVGRSGTFIAI
... .||.|.. . . .|.. |. | .||| ||.||.||..|
eylklpfpddgtvPsleillrfldlvdeflnedpggvvaVHCkaGlgRtGtlvaa
|
|||||||||
0048567 | (Phosphotyrosine protein) phosphatases II | 1381-1457 | 2.1e-08 | 28.7 | In-house | 16-101 (157) | alignment | ||
Range on Protein: 1381-1457
Range on HMM: 16-101/157.0
AYYTIRTFKINNKDDESFEVKQ--FHYTAWPDFGvPDHPNPIISFIRRVNN-----STHTGPLVVHCSAGV---GRSGTFIAIQSMM
... . . .. . | . . .... . ||| | . . ...||...|. . . ....|||.|| ||..|.|. ..
yfallprlpkslynalyFsiddglvyedfffdfG.PlnlailyrFilklnkflkilelagkaiavhckaglkkrgrtatLigcYlil
|
|||||||||
subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 1595-1662 | 3.3e-08 | 27.5 | In-house | 70-134 (347) | alignment | ||
Range on Protein: 1595-1662
Range on HMM: 70-134/347.0
SDYINASYVDGYLRCNQFIMTQGPLSNTVDDFWRMIWEHRVSAIVMLcglVEDGKDQSVQYWPKDQLT
|||||.. ...|.|| || .|| |||.|. .|. .| . | ||.... . . .|.
etyinashikfdnaskeyiltqyplpdtvrdfwkmvsvtkvtqvvti...fepikdeaieefanatls
|
|||||||||
subfamily_Sponge-PTP-2_pd | Subfamily Sponge-PTP-2 | 1543-1670 | 3.4e-08 | 26.6 | In-house | 3-98 (169) | alignment | ||
Range on Protein: 1543-1670
Range on HMM: 3-98/169.0
KQFEKLNSIDVAIPSQYISASLPVNRAKNRYPDILPYESYRVRLLMLPGVSGSDYINAsyvdgylrcnqfimtqgplsntvddfwRMIWEHRVSAIVMLC
|....|. . .| . . | | .| .||| | ||.| . ||||||| ||||| | ||.|
kgynelkefmktieynnfmaeltcnetknrpagplapshtrvklqrvmedlgsdyina...........................rmiwetnasvivvlg
GlvedgKDQSVQYWPKDQLTQYGDMFIE
. |. ..||. . | |
d.....tddknnfwpekedyqlhpavil
|
|||||||||
subfamily_Sponge-PTP2_pd | Subfamily Sponge-PTP2 | 1545-1712 | 4.2e-08 | 26.2 | In-house | 4-153 (169) | alignment | ||
Range on Protein: 1545-1712
Range on HMM: 4-153/169.0
FEKLNSIDVAIPSQYISASLPVNRAKNRYPDILPYESYRVRLLMLPGVSGSDYINAsyvdgylrcnqfimtqgplsntvddfwRMIWEHRVSAIVMLCGl
...|. . .| . . | | .| .||| | ||.| . ||||||| ||||| | ||.| .
ynelkefmktieynnfmaeltcnetknrpagplapshtrvklqrvmedlgsdyina...........................rmiwetnasvivvlGd.
vedgKDQSVQYWPKDQLTQYGDMFI-----------ET--ISETDTGFYVIREITITHTKQGNEVRN-IKQFHYTDWSENKT
|. ..||. . | | | . .| . |... . ..| . .. .||. | .|
....tddknnfwpekedyqlhpavilGewytdslyvrtdkvhpntsgveglfevslvihsydddvteqlsllhystwpqngv
|
|||||||||
Ig_3 | Immunoglobulin domain | 377-447 | 4.6e-08 | 25.2 | Pfam-A | 6-72 (75) | alignment | ||
Range on Protein: 377-447
Range on HMM: 6-72/75.0
SQIESETILPVGdsVVLSCTVTGSP-APMIRWYrdgsIMNDG-IATATEGLIIQSNLTLANLQQNQTGVYQCV
..... .. . | |.|...|.| .| |.|| | ... . . ...| ||. . . ...|.|.||
vspsptvtsggn..vtLtCsaeggpppptisWy....ietppelqgsegssssestLtissvtsedsGtYtCv
|
|||||||||
subfamily_eak_pd | Subfamily eak | 1420-1505 | 1.1e-07 | 25.6 | In-house | 223-310 (332) | alignment | ||
Range on Protein: 1420-1505
Range on HMM: 223-310/332.0
IISFIRRVNNSTHTGPLVVHCSAGVGRSGTFIAIQSMMLMMETEGK--VDVFNFVLDMRHKRNYMVQTEAQYMFVHDSLVELIKVGNS
. |.... . . .. .. | |.|.|. |. .. ... | | ...| ...||.. | .. |. |... ... .. |.
lsstlkkyihtppsfapiiqsarGsaraGvfvvidllirlidnkkknlysvedlilkvkskrihsvlvalqhsfiyeivldyllrrnn
|
|||||||||
I-set | Immunoglobulin I-set domain | 577-660 | 1.9e-07 | 22.7 | Pfam-A | 8-83 (90) | alignment | ||
Range on Protein: 577-660
Range on HMM: 8-83/90.0
PPIIVLRGDTVSFSCLASSIPVPNITWFRNDSSGPVslfddtesvVSIIST---StdgltTNSTLTI---TLESDGEYFCFASNDFFNDT
.. | |..|...| .. | |...|....|. . .. . ..|||| . . |.| | |.| . ...
kdvevseGesvelectveGepepsvsWakdgselks.........sqrvkvtvee.....aeytLtIsnvevsDeGkYtckatnsagkae
|
|||||||||
Ig_3 | Immunoglobulin domain | 578-654 | 3e-07 | 22.6 | Pfam-A | 3-75 (75) | alignment | ||
Range on Protein: 578-654
Range on HMM: 3-75/75.0
PIIVLRGDT------VSFSCLASSIP-VPNITWFrndssgpvslfddtESVVSIISTSTDGLTTNSTLTIT---LESDGEYFCFASN
|.| .. | |...| | . | |.|.| .. .....| . ...|||||. | .| | | |||
visvspsptvtsggnvtLtCsaeggpppptisWy..............ietppelqgsegssssestLtissvtsedsGtYtCvasN
|
|||||||||
Ig_2 | Immunoglobulin domain | 577-664 | 5.1e-07 | 21.6 | Pfam-A | 7-76 (80) | alignment | ||
Range on Protein: 577-664
Range on HMM: 7-76/80.0
PPIIVLRGDTVSFSCLASSIPVPNITWFRNdssgpvslfddtesvVSIISTSTDGLTTNStltITLESDGEYFCFASNDFFNDTSEPA
|| | |..| . | |.. | |...| .. ...|.|...| ... ...| | |.| |||. .|..
pptvvtegenvtLtCqapgnptpkvqwykd...............geelsqsqnalfipn...vsaedsGtYtCrasnsegskqsnsv
|
|||||||||
subfamily_PTEN_pd | Subfamily PTEN | 1378-1492 | 5.2e-07 | 24.8 | In-house | 52-172 (184) | alignment | ||
Range on Protein: 1378-1492
Range on HMM: 52-172/184.0
QVLAYYTIRTFKINNK-DDESFEVKQFHYTaWPDFGVPDHPNPIISFIRRVNNS-------THTGPLVVHCSAGVGRSGTFIAIQsMMLMMETEGKVDVF
..| . .|| | ..... |.|. . ... || | ....... .. .. |||| || ||.|. |. .. .. .| . ..
kflekkhkdhykiynlrserkydskkfdgr.vavypfdDhnppplelleeivediekwleedkknvvvvHCkaGkGRtGvlivay.llkslllekaeeal
NFVLDMRHKRNYMVQTEAQYMFV
.. .| | . |. .| .|
elfaeaRtknkkgvtiPsqrRYv
|
|||||||||
V-set | Immunoglobulin V-set domain | 376-458 | 5.5e-07 | 20.4 | Pfam-A | 4-102 (114) | alignment | ||
Range on Protein: 376-458
Range on HMM: 4-102/114.0
ISQIESETILPVGDSVVLSCTVT-GSPAPMIRWYRDGS------IM----------NDGIATATEGLIIQSN-----LTLANLQQNQTGVYQCVFVSPgv
.|| ... . .|.|| |.|... . .|.||.... |. . .. | ... ||. ||... .|.|.| ..
vsqsprpvtvaeGgsvtLpCfysssensqsiyWykqktgskpeliiryvaetnnskvgesfsgrvtlssngsksdfsLtiqnlrleDsGtYtCavsds..
ggvaY
.
....n
|
|||||||||
PTEN_1 | 1396-1452 | 8.1e-07 | 24.0 | In-house | 88-149 (196) | alignment | |||
Range on Protein: 1396-1452
Range on HMM: 88-149/196.0
ESFEVKQFH--YTAWPDFGVPDhPNPIISFIRRVNNST----HTGPLVVHCSAGVGRSGTFIA
|.|. ... ..|.|.|. . .. ..... .. . . .||| ||.||||| .|
eeffksgveylhfpieDhgaps.lselfdicksfiewllsdpngnvVlVHCkaGlgRsGtvva
|
|||||||||
C2-set_2 | CD80-like C2-set immunoglobulin domain | 679-751 | 2e-06 | 17.8 | Pfam-A | 8-82 (89) | alignment | ||
Range on Protein: 679-751
Range on HMM: 8-82/89.0
SAPPVViNSSIIINC-TSEGFPLPAISWLINETNLTGVDEFTVNTEMMSANRSVSTLSGNINN--NNTRLVCVASN
| .. | . .| ...|.| | |.|. .. .|... ... | ..|||. . ... |.|..|.
sllege.neevvatCvsaggkPapritWyldgkeleaietsseqdeesglvtvtstlkltpsredhgksltCqvsy
|
|||||||||
PTPc_motif_SM00404 | 1414-1479 | 2.7e-06 | 22.3 | In-house | 63-121 (140) | alignment | |||
Range on Protein: 1414-1479
Range on HMM: 63-121/140.0
PDHPNPIISFIRRVnnSTHTGPLVVHCSAGVGRSGTFIAIQSMMLMmeTEGKVDVFNFVldmRHKR
.. . ...||... . | .||| ||| ||.|.|. |. . ....|| ...|
skyldkvldfiena..ekkggkvlVHCqaGvSRSatliiaYlmryr..qlslaeayefv...kerR
|
|||||||||
I-set | Immunoglobulin I-set domain | 198-271 | 6.2e-06 | 17.9 | Pfam-A | 4-75 (90) | alignment | ||
Range on Protein: 198-271
Range on HMM: 4-75/90.0
IIQPVDVHVPVNGTAAFSCSISPDsALINITWYSSEGMVASEDVINDFNDPGLSVLVINNVTESEGGvAYYCVA
... || | .. .. ..|... . ....|.. . ..|.. .. .. . . |.|.||..|. | | |.|
tqklkdvevseGesvelectveGe.pepsvsWakdgselkssqrvkvtveeaeytLtIsnvevsDeG.kYtcka
|
|||||||||
DSPc | Dual specificity phosphatase, catalytic domain | 1408-1478 | 6.2e-06 | 21.1 | Pfam-A | 50-113 (133) | alignment | ||
Range on Protein: 1408-1478
Range on HMM: 50-113/133.0
WPDFGVPDHPNPIISFIRRVnnSTHTGPLVVHCSAGVGRSGTFIAIqsmMLMMETEGKVD-VFNFVldmRHK
. . .. . ...||... . . .||| ||. ||.|.|. ||.. . ... ..|| . .
etetkiskeleeavefieka..eqkgkkvlVHCqaGisRSatliia...YlmktknlslneAyefv...ker
|
|||||||||
DSPc | Dual specificity phosphatase, catalytic domain | 1408-1478 | 6.2e-06 | 21.1 | In-house | 50-113 (133) | alignment | ||
Range on Protein: 1408-1478
Range on HMM: 50-113/133.0
WPDFGVPDHPNPIISFIRRVnnSTHTGPLVVHCSAGVGRSGTFIAIqsmMLMMETEGKVD-VFNFVldmRHK
. . .. . ...||... . . .||| ||. ||.|.|. ||.. . ... ..|| . .
etetkiskeleeavefieka..eqkgkkvlVHCqaGisRSatliia...YlmktknlslneAyefv...ker
|
|||||||||
Ig_3 | Immunoglobulin domain | 210-271 | 7.2e-06 | 18.1 | Pfam-A | 16-73 (75) | alignment | ||
Range on Protein: 210-271
Range on HMM: 16-73/75.0
GTAAFSCSISPDSALINITWYsseGMVASEDVINDFNDPGLSVLVINNVTESEGGVaYYCVA
|. ..||. .. .|.|| .|. .. .... |.|.| .||.. |. | |||
gnvtLtCsaeggpppptisWy...ietppelqgsegssssestLtissvtsedsGt.YtCva
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Ig_3 | Immunoglobulin domain | 672-751 | 7.6e-06 | 18.1 | Pfam-A | 2-75 (75) | alignment | ||
Range on Protein: 672-751
Range on HMM: 2-75/75.0
PVIITNPSAPPVVINSsIIINCTSEGFP-LPAISWL------INETNLTGVDEFTVNTEmmsanrSVStlsgnINNNNTrLVCVASN
|||...|| ... . . ..|..||.| | |||. .. .. .. | |.. . ||. ... | |||||
Pvisvspsptvtsggn.vtLtCsaeggpppptisWyietppelqgsegssssestLtis......svt.....sedsGt.YtCvasN
|