Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 1309-1589 | 2.5e-154 | 507.4 | In-house | 7-287 (287) | alignment | ||
Range on Protein: 1309-1589
Range on HMM: 7-287/287.0
FNRMSKPDTKTGRTGFIDQFTVLEQVTQRPDEVTHNIASQNNDKNRSTQFLPRDNYRVPLKGEHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMI
|..... ....|..|| .|||||||||||.|||||||||||.||||.||.|..|||||.||||||||||||||.||||||||||||||||||||||||.|
fgefvakghakgnegfknqftvleqvtqredevthniasqnkdknRltqilvpdnyrvllkgehpdyinavfidgykekkafiiaesPmfntarnfWkli
DDRNVTAIVMLCHEKEIDQEVCYQYWPSTPSgLVIGEYAIMLSSEEIYNGYIERKLEVKNTN-TGSTQSVMQYQITNWVSTRKMAKPQTILSVIEEMYKT
||||||||||||.||| |.||||||||.. | .|.|||.|.| .||...|||||||||||.| .|..|.|.||||||| ||.|...||||| ||||||||
ddrnvtaivmlcqekendeevcyqyWpeeks.vvlGeyniellneevnagyierklevknknkagdkqqvkqyqitnWdstgkvtepqtillvieemykt
QRRRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYLDSFETYSNF
||.||||||||||||||||||||||||||||||||||||||||||||||||||||||||.||..|..|||.|||||||||.|
qrkrgntsivvhCsdtvGrsamfcaaattinkckteGviDvfqvlksqriqkpgsvqtveqykfindivleyldsfetysdf
|
|||||||||
subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 1012-1302 | 4e-135 | 444.4 | In-house | 1-287 (287) | alignment | ||
Range on Protein: 1012-1302
Range on HMM: 1-287/287.0
LIPVGQFGEFVANGHAKGNEGFKNQYCTLNS-GDNEHSVTIAVTPSNRPLNRFGNIVVYDDNRILLNqipgntDCQNDYINACYIDGYSQDYKYIATQGP
||||..||||||.||||||||||||...|.. ...|..||......|...||. .|.|.|..|.||. ....|||||..||||......|....|
lipvekfgefvakghakgnegfknqftvleqvtqredevthniasqnkdknRltqilvpdnyrvllk......gehpdyinavfidgykekkafiiaesP
VTKTLVDFWRLIWQERPPVIVMVTNLKEDTTIKCHQYWPEHGSTSYGPFRIELTKEQVLTDYTIRKMQLTLLGSDQPPLMITQYHFTSWPDHG-VPEYAT
...|...||.||.......|||....||... .|.|||||. |...|...|||..|.| ..|..||.... ..........||..|.|...| |.|..|
mfntarnfWkliddrnvtaivmlcqekendeevcyqyWpeeksvvlGeyniellneevnagyierklevknknkagdkqqvkqyqitnWdstgkvtepqt
SILQFHRRIKNEYKPTKGPMLVHCSAGVGRTGTFMAIDMGLQQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLESVTCGNTQVDS
..|......|...|.......||||..|||...|.|..........||.||........|.|....|||..||.|.||.|||......|..|.
illvieemyktqrkrgntsivvhCsdtvGrsamfcaaattinkckteGviDvfqvlksqriqkpgsvqtveqykfindivleyldsfetysdf
|
|||||||||
subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 1012-1298 | 2.6e-129 | 425.2 | In-house | 1-288 (290) | alignment | ||
Range on Protein: 1012-1298
Range on HMM: 1-288/290.0
LIPVGQFGEFVANGHAKGNEGFKNQYCTLNSGDNEHSVTIAVTPSNRPLNRFGNIVVYDDNRILLNQIPGNTDCQNDYINACYIDGYSQDYKYIATQGPV
||||..||||||||||||||||.||. .|.||..||.||...|.||..|||| |||||||||| |..|.|. ||.|.|||||||.||.....||||||||
lipvdkfgefvanghakgnegfrnqfkmldsgesehtvtvgltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgykekkqyiatqgpv
TKTLVDFWRLIWQERPPVIVMVTNLKEDTTIKCHQYWPEHGSTSYGPFRIELTKEQVLTDYTIRKMQLTLLGSDQPPLMITQYHFTSWPDHG-VPEYATS
..||||||.|||||. ..|||.|| .|. . ||.||||......||.|.|.|..|..|..|..||.... |.... ..|||..|.|...| |....|.
sntlvdFWkliwqekvtiivmltniieegkvkCqqYWpdsdtkaygefsikllneetlneyierklevknknsagakqsvtqyqitnwdstgkvtnpqti
ILQFHRRIKNEYKPTKGPMLVHCSAGVGRTGTFMAIDMGLQQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLESVTCGNT
.|......|...|.......||||..|||...|.|..........||.||........|.|....|||..|| .... ||..... .|
llvieemyktqrkrgntsivvHCSdtvgrsavfcaaattinkcktegvidvfqvlksqRiqkpgsvqtvqqyqgifqivltyldsfet
|
|||||||||
subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 1315-1587 | 4.9e-125 | 411.2 | In-house | 13-290 (290) | alignment | ||
Range on Protein: 1315-1587
Range on HMM: 13-290/290.0
PDTKTGRTGFIDQFTVLEQvTQRPDEVTHNIASQNNDKNRSTQFLPRDNYRVPLK--GEHPD----YINAVFINGYKEKKAFIIAESPMFNTARNFWKMI
....|..|| .||..|.. .... .||....|.|. .||.......|..|..|. ..|.| ||||..|.||||||..|....|..||...|||.|
nghakgnegfrnqfkmlds.gesehtvtvgltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgykekkqyiatqgpvsntlvdFWkli
DDRNVTAIVMLCHEKEIDQEVCYQYWPSTPSGLvIGEYAIMLSSEEIYNGYIERKLEVKNTNT-GSTQSVMQYQITNWVSTRKMAKPQTILSVIEEMYKT
....||.||||....| ....|.||||.... .||. | |..||..|.||||||||||.|. |..|||.||||||| || |...|||||.||||||||
wqekvtiivmltniieegkvkCqqYWpdsdtka.ygefsikllneetlneyierklevknknsagakqsvtqyqitnwdstgkvtnpqtillvieemykt
QRRRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYLDSFETYS
||.||||||||||||||||||.||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
qrkrgntsivvHCSdtvgrsavfcaaattinkcktegvidvfqvlksqRiqkpgsvqtvqqyqgifqivltyldsfetys
|
|||||||||
subfamily_PTPRD_pd | Subfamily PTPRD | 1012-1372 | 2e-123 | 408.0 | In-house | 4-361 (564) | alignment | ||
Range on Protein: 1012-1372
Range on HMM: 4-361/564.0
LIPVGQFGEFVANGHAKGNEGFKNQYCTLNSGdNEHSVTIAVTPSNRPLNRFGNIVVYDDNRILLNQIPGNtdCQNDYINACYIDGYSQDYKYIATQGPV
||| .. |.||. .|... |...| ....| ...... | | |.. ||. ||| || .|. |....|. . ||||| .|||| .. .|||||||.
pipvaelkehvaklkansdlkfeeeykkieeg.qqftweaankpaNkaKNRyanivaYdhsRVvLskvegd..egsDYINAsfidgyrkrkayIAtqgPl
TKTLVDFWRLIWQERPPVIVMVTNLKEDTTIKCHQYWPEHGSTSYGPFRIELTKEQVLTDYTIRKMQLtLLGSDQPPLMITQYHFTSWPDHGVPEYATSI
.|. ||||..|... .|||.|.|.| .. |||.||||.|...|| . ..|..|. |.||.||...| ... ...|.||||||||||||.|||.
aetiedFWRmvweqnsstiVmltkleEkgkvkchkYWPekgtetygeltVtleeeeeladyeirtfkl.kkkkssesreVrqFhFtsWPdhgvpesatsl
LQFHRRIKNEYKPTKGPMLVHCSAGVGRTGTFMAIDMGLQQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLESVTCGNTQVDSRNARIVFNR
|.. |.... .|..||..|||||||||||||..||. |.....|. .|| ......|.|| |||| .||||. .|.|| ..||||.|.|.| . ...
LdlirkvralnepdagPivVhCSaGVGRTGtfividamlerikeektvDiyqyvkalrkqRnamVqteeQYiFiheailealacgntevesenlkqhlqk
MSKPDTKTGRTGFIDQFTVLE-QVTQRPDEVTHNIASQNNDKNRSTQFLPRDNYRVPLKGEH
... ...|. ||. | |. . . ..| . ..|..||| .. |. .. || |. ..
LaeveedtemtgleleFqrLatakeieleefavatkpknkkknrfsnilalescrvvlsair
|
|||||||||
subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 1012-1314 | 5.5e-103 | 339.3 | In-house | 3-304 (305) | alignment | ||
Range on Protein: 1012-1314
Range on HMM: 3-304/305.0
LIPVGQFGEFVANGHAKGNEGFKNQYCTLNSGdnEHSVTIAVTPSNRPLNRFGNIVVYDDNRILLNQIPGNTdcQNDYINACYIDGYSQDYKYIATQGPV
| . .. ... . ... ..|...|| .| . |.|. . . |. ||. .|...||.|| |.. . . ..|||||.|.|||.. |||..|||.
iialddlaayikearvysdkgleaqykslyee..eesidvgkkeankaknrlkeitlldddriiltekesld..dsdyinasyvdgykrkkkyivaqgPl
TKTLVDFWRLIWQERPPVIVMVTNLKEDTTIKCHQYWPEHGST--SYGPFRIELTKEQVLTDYTIRKMQLTLLGSDQPPLMITQYHFTSWPDHGVPEYAT
.|..||||||..|.. .|||.|.|.|. ||.||||| . .|.| .||. |. .||..||.... .|. ..||..|.|||||||..||
kntvadfWrliveekvstivmltklveggkdkCrqYWpesktekkefgefsvelksektasdyieRklkisiededkesrtvlqyqltdWPdhGvpqfat
SILQFHRRIKNEYKPTKG-PMLVHCSAGVGRTGTFMAIDMGLQQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLESVTCGNTQVDSRNARIV
|.|.. .|.....| || |.||||||||||||.|.|.|. |....||. .|. .....|..||||||| ||| |. ||. | .|||.|.. | |.
sllslikrvqkdqkkdkgvpllVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkmvqtldqYvflhdaldelitcgdtsiigsnlrar
FNRMSK
|.. |
vnklkk
|
|||||||||
subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 1013-1328 | 4.4e-98 | 323.2 | In-house | 2-315 (318) | alignment | ||
Range on Protein: 1013-1328
Range on HMM: 2-315/318.0
IPVGQFGEFVANGHAKGNEGFKNQYCTLNSGDNEHSVTIAVTPSNRPLNRFGNIVVYDDNRILLNQIPGNTdcQNDYINACYIDGYSQDYKYIATQGPVT
|.| .. . |.. ...|. ....| |. ... . . ...| |. ||. ||. ||. |..|... |.. . ||||| ||||| .. .|||.|.|..
isvedleshvrrlresGelllseeyerlsrseetvtslkslepvnkaknryanilaydhtrvkLqmlegee..gsDyinanyidGyrrkkayiaaqaPlp
KTLVDFWRLIWQERPPVIVMVTNLKEDTTIKCHQYWPEHGSTSYGPFRIELTKEQVLTDYTIRKMQLTLLGSDQpPLMITQYHFTSWPDHGVPEYATSIL
.|. ||||..|. ||||.|...| . .|.|.|||..||.||| ..||..| |.||..|....| .... .. |||.|||||.|||| ..|.|
etieDfWrmvWeqnsavivmltqeeergkakvhryWPskgsrsygklvvelkeevelsdyvlrefkvtrteeee.srqvrqyhytsWpdegvpesgasll
QFHRRIKNEY-KPTKGPMLVHCSAGVGRTGTFMAIDMGLQQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLESVTCGNTQVDSRNARIVFNR
.. |.... |...||..|||||||||||.|.|.|. |.....|. .|. .....|.|| |||| |||.|. |..|| ...|.|.||... | ..
dlvrqvskaqqksgagpivvhCsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqtedqyefiydvllealasgdtevdasdlrsrire
MSKPDTKTGRTGFIDQF
. ..|...|.| . .|
lreqdpesgttemdaef
|
|||||||||
0051299 | (Phosphotyrosine protein) phosphatases II | 1011-1292 | 7.9e-97 | 319.4 | In-house | 3-285 (288) | alignment | ||
Range on Protein: 1011-1292
Range on HMM: 3-285/288.0
NLIPVGQFGEFVANGHAKGNEGFKNQYCTLNSGDNEHSVTIAVTPSNRPLNRFGNIVVYDDNRILLNQIPGntDCQNDYINACYIDGYSQDYKYIATQGP
. |.| .. ..| . .|.|. |..... .| | .....|. | |.. ||. .|. ||..|. |. ..| . .||||| ||||| .. |.||||||
teisveellklvlkllangltglleefeellsllpdltlsaallpenleknRysdilpydhsRVkLsvldg..vegsdYinAsyidgynlkrkfIatqgP
VTKTLVDFWRLIWQERPPVIVMVTNLKEDTTIKCHQYWPEHGSTSYGPFRIELTKEQVLTDYTIRKMQLTLLG---SDQPPLMITQYHFTSWPDHGVPEY
.|. ||||..|... .||||.|.| |. .||.||||..||. ||.....|..|.|| |||.|....| |. |. ....|..|.|.|||||||..
lpntvedFWrmvweqnvrvIvmltklvelgrekcaqYwplggsltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpds
ATSILQFHRRIKNEYKPTKGPMLVHCSAGVGRTGTFMAIDMGLQQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLES
....|.| |.... .....||..||||||||||||| |.|. |.| |||||.|. ......|.||. |||| .||.|| .|.||
pellldflrlvrkalasgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyealley
|
|||||||||
subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 1012-1327 | 3e-96 | 317.3 | In-house | 4-317 (319) | alignment | ||
Range on Protein: 1012-1327
Range on HMM: 4-317/319.0
LIPVGQFGEFVANGHAKGNEGFKNQYCTLNSGDNEhSVTIAVTPSNRPLNRFGNIVVYDDNRILLNQIPGNTDcqNDYINACYIDGYSQDYKYIATQGPV
|.| .. | . . ...|. ...... .|. ..|. ... | .. |.. ||. ||. || |. | ...| . ||||| .|||| . |.||||.|.
eievqeLkerlkalastgetllekefkllkeavnd.tfdsaskeenkkknryqnilaydrtrvvlseldgveg..sdyinasfidgyqerekfiatqaPl
TKTLVDFWRLIWQERPPVIVMVTNLKEDTTIKCHQYWPEHGSTSYGPFRIELTKEQVLTDYTIRKMQLTLLGSDQPPLMITQYHFTSWPDHGVPEYATSI
.|. ||||..|.|. ..||.|.|.| .|...||||. ..|| . ..| .|. | || |||..| . |. .......|.||||.|||.|||.
entiedfWrmvWeeessivvmltklveklkvklkkywpeenfeeyGrlivtleeeeeledyiirklklnkkssevetRevkhfqyteWpdhdvPekatsl
LQFHRRIKNEYK-PTKGPMLVHCSAGVGRTGTFMAIDMGLQQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLESVTCGNTQVDSRNARIVFN
|.. .||.. . ...||. |||||||||||||...|. |.. ..|| .|. |.....| || |||. .||.|. .|.|| |..|.|... .. | .
ldllkrirksrektqsgPivvhCsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyealleaveagdteievqdlrdrlk
RMSKPDTKTGRTGFIDQ
.... ...|| ||. .
qlaekvadtgetglere
|
|||||||||
0050432 | (Phosphotyrosine protein) phosphatases II | 1026-1297 | 7.2e-95 | 313.1 | In-house | 37-303 (308) | alignment | ||
Range on Protein: 1026-1297
Range on HMM: 37-303/308.0
HAKGNEGFKNQYCTLNSGDNEHSVTIAVTPSNRPLNRFGNIVVYDDNRILLnqipgntDCQNDYINACYIDGY--SQDYKYIATQGPVTKTLVDFWRLIW
.|... ... .. .|.| . .. ..| | |...||. .|. || .|. | | .||||| |.||| .. |.|||||| .|. ||||..|
kaldlglleeefeellsvkplleysvallpenkdkNrykdilpydhsRVkl.......degsdYInAsyvdgyssklprkfIatqgPlpntvedFwrmvw
QERPPVIVMVTNLKEDTTIKCHQYWPEH---GSTSYGPFRIELTKEQVLTDYTIRKMQLTLLGSDQPpLMITQYHFTSWPDHGVPEYATSILQFHRRIKN
... .||||.|.| |. .||.||||. ||. ||.|...|..|.|| |||.|...|| ||... ...|..|.|.|||||||......|.| .....
eqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseevlddytvrtleltnlgdges.rtvthfhytnWpdhgvPpspeilldflelvrk
EYkpTKGPMLVHCSAGVGRTGTFMAIDMGLQQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLESVTCGN
. .||..||||||||||||| |.|. |.| |||||.|. ....|.|.||. |||| .||.|. .|.|| . .
sl..pggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylflyralleylklkl
|
|||||||||
0040438 | (Phosphotyrosine protein) phosphatases II | 1017-1317 | 2.4e-94 | 311.5 | In-house | 4-300 (317) | alignment | ||
Range on Protein: 1017-1317
Range on HMM: 4-300/317.0
QFGEFVANGHAKGNEGFKNQYCTLNSGDNEhSVTIAVTPSNRPLNRFGNIVVYDDNRILLNQIPGntDCQNDYINACYIDGYSQDYKYIATQGPVTKTLV
.. ... ..... ........| | . . . ..| | |...||. .|. ||..|. |. ..| | .||||| |.||... |.|||||| .|.
dlllalldllksdftalleefedllslkld.tysvaelpenkdknrypdilpydhsRVkLsplgg..dldsdYInAsyvdgpnlkrkfIatqgPlpntve
DFWRLIWQERPPVIVMVTNLKEDTTIKCHQYWPEHGSTSYGPFRIELTKEQVLTDYTIRKMQLTLLgSDQPPLMITQYHFTSWPDHGVPEYATSILQFHR
||||..|... ||||.|.|.|. .||.||||. ... ||.|...|..|..| ..|.|..... | |......|..|.|.|||||||.. ...|.| .
dFwrmvweqgvtvivmLteleelgrekcaqYwplgetltygdftvtllseeelagitlrtlevedl.gdsesrtvthfhytgWpdhgvppspdllldfle
RIKNEYKPTKGPMLVHCSAGVGRTGTFMAIDMGLQQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLESVTCGNTQVDSRNARIVFNRMSKPD
.... ... .||.|||||||||||||| |... |.| |||||.|. ......|.||...||| .||.|. ||.|| .....| .. . . .. |.
avrealedpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleylkrkltlepaselklkllkllipl
T
.
a
|
|||||||||
subfamily_PTPRB_pd | Subfamily PTPRB | 1011-1294 | 5.2e-92 | 303.0 | In-house | 5-286 (293) | alignment | ||
Range on Protein: 1011-1294
Range on HMM: 5-286/293.0
NLIPVGQFGEFVANGHAKGNEGFKNQYCTLNSGDNEHSVTIAVTPSNRPLNRFGNIVVYDDNRILLNQIpgNTDCQNDYINACYIDGYSQDYKYIATQGP
. | . .| |.|.. .|. . .|...| .|.. .....|..| .. || ||. ||. || .|. |... ... ..||||| ||.||.. ..||||||
kpiklekfeehvkkmkadsdlrfseeyeelkavgkdqavkaaelavnraknrytnilpydhsrvkLaal..kdesgsDYinanyipgynsprefiatqGP
VTKTLVDFWRLIWQERPPVIVMVTNLKEDTTIKCHQYWPEH-GSTSYGPFRIELTKEQVLTDYTIRKMQLTLlgsDQPPLMITQYHFTSWPDHGVPEYAT
. .|. ||||..|... .|||.|.| | .||..|||.. .. || ...|..|..|.|..||..... .. ..|||||||||||||| ..
lpetvddfWrmvwekkssiivmltqlvekgkvkCeeYWPadeepvlyGdikvtlvaeeeledwvirelkiek...ekeerkvrqyhftsWpdhgvPektk
SILQFHRRIKNEY--KPTKGPMLVHCSAGVGRTGTFMAIDMGLQQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLESVT
..|.| |..... . .|.|..|||||||||||||.|.|. ||. |.| .||..|. ..|..|. .||| .||||....||. ..
tlldfvrtvreaiektaskrPivvhCsaGvGRtGtfialdrllqaieeedyvdifgivaelReeRnllvqtekqYifihqcvldllr
|
|||||||||
0036941 | (Phosphotyrosine protein) phosphatases II | 1027-1299 | 4.3e-91 | 300.6 | In-house | 9-283 (297) | alignment | ||
Range on Protein: 1027-1299
Range on HMM: 9-283/297.0
AKGNEGFKNQYCTLNSGDNEHSVTIAVTPSNRPLNRFGNIVVYDDNRILLnqipgnTDCQNDYINACYIDGYSQDYKYIATQGPVTKTLVDFWRLIWQER
.... ... .. .| . . | ..| | |...||. .|. ||..|. | .| .|||||.|.|||....|.|||||| .|. ||||..|...
llflalllkefeellpllllgslsvallpenleknRykdilpydhtRVkl......ddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqn
PPVIVMVTNLKEDTTIKCHQYWPEH--GSTSYGPFRIELTKEQV--LTDYTIRKMQLTLLGSDqPPLMITQYHFTSWPDHGVPEYATSILQFHRRIKNEY
.||||.|.| |. .||.||||. .| ||.|...|....| |.|||.|....| .|.. .....|..|.|.||||||||...|.|.| ..... .
vtvIvmltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgng.esrtvthfhytgwpdhgvpespaslldfielvrkvl
K--PTKGPMLVHCSAGVGRTGTFMAIDMGLQQAE---KEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLESVTCGNTQ
| | .||.||||||||||.||| |.|. ||| | ||||.|| ....|.|.||. .||| .||.|. .|.|| . ...|
kllpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallellkkkltk
|
|||||||||
0046845 | (Phosphotyrosine protein) phosphatases II | 1033-1298 | 1.1e-90 | 299.2 | In-house | 2-279 (284) | alignment | ||
Range on Protein: 1033-1298
Range on HMM: 2-279/284.0
FKNQYCTLNSGDNEH--SVTIAVTPSNRPLNRFGNIVVYDDNRILLNQIPGNtDCQNDYINACYIDGY-----SQDYKYIATQGPVTKTLVDFWRLIWQE
.. .. .|.| . |...|. | |. .||. .|..||..|. |. ..|. . .||||| |.||| . |.||||||. .|. ||||..|..
leeefeellsltvklllslsvallpenlsknRykdilpydhsRVklksldgd.ledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweq
RPPVIVMVTNLKEDTTIKCHQYWPEHG-STSYGPFRIELTKEQVLTDYTIRKMQLTLLGSDQPPLMITQYHFTSWPDHGVPEYATSILQFHRRIKNEYK-
. .||||.|.| |. .||.||||. | . ||.|...|..|.| |||.|...|| || .......|..|.|||||||||......|.| | ... ..
nvrvIVmltelvengrekcaqYwplegevltygdftvtllseevkddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrellen
-PTKGPMLVHCSAGVGRTGTFMAIDMGLQQAEKEG---GIDIISIINKMRQQRMKMVQTADQYIFVNDAVLESVTCGNT
|..||..||||||||||||| |.|. |.| |||| |.|. ......|.||. |||| .||.|| .|.|| . ...|
lpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleylklklt
|
|||||||||
0047943 | (Phosphotyrosine protein) phosphatases II | 1026-1291 | 2.7e-89 | 294.6 | In-house | 7-270 (273) | alignment | ||
Range on Protein: 1026-1291
Range on HMM: 7-270/273.0
HAKGNEGFKNQYCTLNSGDNEHSVTIAVTPSNRPLNRFGNIVVYDDNRILLnqipgnTDCQNDYINACYIDGYSQDYKYIATQGPVTKTLVDFWRLIWQE
...|. ... .. .| | .... ..|. | |. .||. .|. ||..|. | .| .||||| |.||| . |.|||||| .|. ||||..|..
kllgltllleefelllslkplltysvallpenkdknrykdilpydhsrvkl......gdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvweq
RPPVIVMVTNLKEDTTIKCHQYWPEHG---STSYGPFRIELTKEQVLTDYTIRKMQLTLLGSDQpPLMITQYHFTSWPDHGVPEYATSILQFHRRIKNEY
. .||||.|.| |. .||.||||. | |. ||.|...|..|.. |||.|...|| ||... ....|..|.|.|||||||.. .|.|.| . ... .
nvrviVmLtelvelgrekcaqYwpleggelsltygkftvtllseetkddytvrtleltnlgtge.srtvthfhytgwpdhgvppslesllefielvrkal
KP--TKGPMLVHCSAGVGRTGTFMAIDMGLQQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLE
. .||..||||||||||||| |.|. |.| |||||.|. ......|.||. |||| .||.|. .|.||
ealpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyealle
|
|||||||||
subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 1020-1300 | 8.5e-89 | 292.7 | In-house | 16-297 (298) | alignment | ||
Range on Protein: 1020-1300
Range on HMM: 16-297/298.0
EFVANGHAKGNEGFKNQYCTLNSGDN---EHSVTIAVTPSNRPLNRFGNIVVYDDNRILLNQIPgnTDCQNDYINACYIDGYSQDYKYIATQGPVTKTLV
...| ..|. |..... .|||. . |.. ..| .|.|. ||. .|. .| |..|... .| . ||||| ....|.. .||||.|.|.|..
klaavkkkkkltgyalefqrlnsvsseieeeekevarkpenkkkNRyadiialdssRvvLeked..adeesdYiNAsflhaykgrnafiatqaPltetve
DFWRLIWQERPPVIVMVTNLKEDTTIKCHQYWPEHGSTSYGPFRIELTKEQVLTDYTIRKMQLTLLGSDqPPLMITQYHFTSWPDHGVPEYATSILQFHR
||||....| .|||.|||.| ..|.|.|||..|.. || ....| .... .|...||.... .. .. | |||||||.||||.|||.|.. |
dFWrmvteedigtiVmltnleeldktkyhkywPdegketygeitvsllskeefadlivrklkvskkkee.kerevrqlhftsWpdkgvpenatsvldllr
RIKNeYKPTKG--PMLVHCSAGVGRTGTFMAIDMGLQQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLESVTCGNTQV
... .. | |..|.|||||||.|||.||| |....|| .|. ... .|..|...||| .||.|. .|||| ....|...
kvra.sqqqagnkpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavlealdsfndei
|
|||||||||
0043336 | (Phosphotyrosine protein) phosphatases II | 1014-1291 | 3.7e-88 | 290.9 | In-house | 3-275 (278) | alignment | ||
Range on Protein: 1014-1291
Range on HMM: 3-275/278.0
PVGQFGEFVANGHAKGNEGFKNQYCTLNSGDNeHSVTIAVTPSNRPLNRFGNIVVYDDNRILLNQIPGNTDcqNDYINACYIDGYSQDYKYIATQGPVTK
.| .. ..... ..... ...... .|.| . . .|| | |...||. .|. || .|. |. ..| | .||||| |.|||.. |.|||||| ..
svkdllkallelllnlktllllefeellsfkl.dtysiallpenkdknrykdilpydhsrvklsllggdld..sdYinAsyvdgynvprkfiatqgPlpe
TLVDFWRLIWQERPPVIVMVTNLKEDTTIKCHQYWPeHGSTSYGPFRIELTKEQVLTDYTIRKMQLTLLGSDQPpLMITQYHFTSWPDHGVPEYATSILQ
|. ||||..|... ..|||.|.|.|. .||.|||| ||. ||.|...|.||..| |||.|.. .| ||.... ...|.||...|||||||| ...|.
tvedFwrmvwelgvttivmLtelvelgrvkcaqYwp.ggsltygdftvtllkeehlddytvrtlevtnlgdges.rtvthyhylgwpdhgvpeslsllld
FHRRIKNEYKPTKGPMLVHCSAGVGRTGTFMAIDMGLQQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLE
| ..... ... .||.||||||||||||||.|... |.|.|||||.|. ......|.||...||| .||.|. .|.||
flkavrealedsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyealle
|
|||||||||
subfamily_PTPRA_pd | Subfamily PTPRA | 1011-1324 | 1e-87 | 289.1 | In-house | 12-326 (330) | alignment | ||
Range on Protein: 1011-1324
Range on HMM: 12-326/330.0
NLIPVGQFGEFVANGHAKGNEGFKNQYCTLNSGDNEHSVTIAVTPSNRPLNRFGNIVVYDDNRILLNQIPGNTDcqNDYINACYIDGYSQDYKYIATQGP
.|| .. | . | |. |.... .| .|. . .. .| |. ||. ||. || .|. |... |. . ||||| .|||| . |.||.|||
fplpvekleeeirirsaddnklfreefnalPagpiqatlelaskeenkeknrvvnilPydfsrvilsvkeGvee..sdyinasfidGykekdkfiaaqGP
VTKTLVDFWRLIWQERPPVIVMVTNLKEDTTIKCHQYWPEHGSTSYGPFRIELTKEQVLTDYTIRKMQLTLLGSD---QPPLMITQYHFTSWPDHGVPEY
..|. ||||.||. . |||.|.||| ||.||||..|. .|| |.|. .|.|| |||.||. .. |. ... ...|.||||||| |||
keetvedfwrmiweqksativmltelkerkeekcaqywPdeGlvtyGnirvevedetvlvdytvrkflvqqlpdatrekksrlvrqfhftswPdvGvPfe
ATSILQFHRRIKNEYKPTKGPMLVHCSAGVGRTGTFMAIDMGLQQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLESVTCGNTQVDSRNARI
. .|.. ...|. . . ||. |||||||||||||...| |.. . |. .|. .....|.|| .|||| || |. ..|| |.|..|
piGmlkllkkvkklnqqsagpivvhcsaGvGrtGtfivldavlervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvlleyylygdteldvsslek
VFNRMSKPDTKTGRTGF
.... . |.| ..|.
hlqklynkitgtdkigl
|
|||||||||
subfamily_PTPRG_pd | Subfamily PTPRG | 1013-1306 | 1e-87 | 289.7 | In-house | 1-300 (563) | alignment | ||
Range on Protein: 1013-1306
Range on HMM: 1-300/563.0
IPVGQFGEFVANGHAKGNEGFKNQYCTLNSGDNEH--SVTIAVTPSNRPLNRFGNIVVYDDNRILLNQIPGNTDCQnDYINACYIDGYSQDYKYIATQGP
.|| .| . ||. ||.|. ||.... |.| ... .. . |.|. || ||| || |. |...||. . ||||| ||||| . ..||||||
vpvkefakhvaslhadgdigfseefealqsetiskdldaehsqkpenkrKnRylnivaydrsRvklsplpgkkkkl.DYinAnyidGyqkskafiatqgp
VTKTLVDFWRLIWQERPPVIVMVTNLKEDTTIKCHQYWPEHGSTSYGPFRIELTKEQVLTDYTIRKMQLTLL----GSD-QPPLMITQYHFTSWPDHGVP
...|. ||||.||... .|||.|||.|.. ||..|||. .| || ... |..|.||. ||.|.... | ... . ....|||.|.|||||||
lkdtfddFWrmiWeqnvaiivmitnlvergrrkcdvYWPkdesetygalqvtlieeevlalytvrtlviknlklkkkkqcdteklvrqyhytkWPdhgvP
EYATSILQFHRRIKNEYKPTKGPMLVHCSAGVGRTGTFMAIDMGLQQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLESVTCGNTQVDSRNA
|... |.| .. . | . ||..||||||||||||....| |.| ..| ... .. ..| || .||| .||||. ||.|| .. ..|.. . .
ehslpvLifvkkssaankaeaGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvqteEqYiflhdalleaiasketellaeqv
R
.
e
|
|||||||||
0039614 | (Phosphotyrosine protein) phosphatases II | 1014-1296 | 4.8e-87 | 287.4 | In-house | 15-292 (297) | alignment | ||
Range on Protein: 1014-1296
Range on HMM: 15-292/297.0
PVGQFGEFVANGHAKGNEGFKNQYCTLNSGDNEhsVTIAVTPSNRPLNRFGNIVVYDDNRILLNQIPGNtDCQNDYINACYIDGYSQ-DYKYIATQGPVT
|.. . .. .|... ...... .| | . .|| | |...||. .|. ||..|. |. ..| | .||||| |.|||.. . |.|||||| .
plsvldlllllekansktllllefeellslkpd..ysiallpenkdknrykdilpydhsrvklkpedgv.dldsdYinAsyvdgydlltrkfIatqgPlp
KTLVDFWRLIWQERPPVIVMVTNLKEDTTiKCHQYWPEHGStSYGPFRIELTKEQVLTDYTIRKMQLTLlgsDQPPLMITQYHFTSWPDHGVPEYATSIL
.|. ||||..|... .||||.|.|.|. ||.||||| |. ||.|...|.|...| .||.|.. .| .......|....|.|||||||......|
etvedFwrmvweqgvtvivmLtklvelgr.kcaqywpeegg.tygdftvtllkvehldgytvrtlevtn...ngesrtvthfqytgwpdhgvppslelll
QFHRRIKNEYK--PTKGPMLVHCSAGVGRTGTFMAIDMGLQQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLESVTCG
.| . ... .. | .||.|||||||||||||| |... |.| |||||.|. ......|.||...||| .||.|. ||.|| . ..
eflelvrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydallellkrk
|
|||||||||
subfamily_PTPRK_pd | Subfamily PTPRK | 1030-1328 | 1e-86 | 285.6 | In-house | 21-312 (314) | alignment | ||
Range on Protein: 1030-1328
Range on HMM: 21-312/314.0
NEGFKNQYCTLNSGdnehsVTIAVTPSNRPLNRFGNIVVYDDNRILLNQIPGntDCQNDYINACYIDGYSQDYKYIATQGPVTKTLVDFWRLIWQERPPV
. |||..| .| | | || ||.|.|. || |. | .| | | ..||||| .||.| . ..|.||||. .|. |||||...|.
gygfkeeyeslfeg.....wdaakkdenreknrsgdilaydrsrvflitidg..dpssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencas
IVMVTNLKEDTTIKCHQYWPEHGSTsYGPFRIELTKEQVLTDYTIRKMQLTLL-GSDQPPLMITQYHFTSWPDHGVPEYATSILQFHRRIKNEYKPTKGP
|||.|.|.| . .|| .||||.... ||....|| . ..|... .| .... | . . .. |..|..||||.|| .||..|.. ||.|. ....|.
ivmltelvevgrvkClkyWPedtev.ygdikvelvetellaelvvrifrveklargqeeirevrqfqflgWpdhdvPvsatgllklvrrvkksqeeeaGr
MLVHCSAGVGRTGTFMAIDMGLQQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLESVTCGNTQVDSRNARIVFNRMSKPDTKTGRTGFIDQF
..|||||| ||||||.|||. |. .|.|| .|. .. ..|.... ||.| .||.|. |..||.. ||.| . . . .. ... |..| . . ..|
ivvhCsaGaGrtGtfiaidivldmieregvvdvfnavktlrsrkvnmveteeqykfiydvileaclcgetaipvsefkalylesirldpqtnssqlkeef
|
|||||||||
0045450 | (Phosphotyrosine protein) phosphatases II | 1012-1291 | 1.6e-86 | 286.1 | In-house | 8-302 (307) | alignment | ||
Range on Protein: 1012-1291
Range on HMM: 8-302/307.0
LIPVGQFGEFVANGHAKGNEGFKNQYCTLNSGDN--EHSVTIAVTPSNRPLNRFGNIVVYDDNRILLNQIPGNtDCQNDYINACYI--------DGYSQD
.|.. .. .|. ......|.. .. .|.| .. .|| | |...||. .|. ||..|. |. ..|. . .||||| |. ||| ..
fidalkllllvllllldfltgllkefekllsvtvfllgeysiallpenkdknrykdilpydhtRVklssldgs.ledsdYiNAsyvrvpllllldgydlk
YKYIATQGPVTKTLVDFWRLIWQERPPVIVMVTNLKEDTTIKCHQYWPEHGST-SYGPFRIELTKEQVLTDYTIRKMQLTLLGSDQPPLMITQYHFTSWP
|.|||||| .|. ||||..|... ||||.|.|.|.. .||.||||. |.. ||.|...|..|..| .||.|.. .| |. .......|..|.|.||
rkfIatqgPlpetvedFwrmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwp
DHGVPEYATSILQFHRRIKNEY--KPTKGPMLVHCSAGVGRTGTFMAIDMGLQQAEKEGG---IDIISIINKMRQQRMKMVQTADQYIFVNDAVLE
|||||.. ..|.| ..... . | .||.||||||||||||||.|... |.| |||| .|. ......|.||...||. .||.|. .|.||
dhgvppsfeelldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyealle
|
|||||||||
subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 1020-1291 | 4.5e-85 | 280.2 | In-house | 10-277 (288) | alignment | ||
Range on Protein: 1020-1291
Range on HMM: 10-277/288.0
EFVANGHAKGNEGFKNQYCTLNSGDNEHSVTIAVTPSNRPLNRFGNIVVYDDNRILLNQIPgnTDCQNDYINACYIDGYSQDYKYIATQGPVTKTLVDFW
. ||. .|....||...| .| . ....|||.. . | . ||. ||. || .|. |.. . . ..||||| ||||. .. ||||||||...|. |||
akvakksarnrtgfseeynsLaalektksvtagrlavnakknRyrnilpyDekrvklkkle..eeagaDYinasyidgekkkkkyiatqgPladtvndfW
RLIWQERPPVIVMVTNLKEDTTIKCHQYWPEHGS-TSYGPFRIELTKEQVLTDYTIRKMQLTllgSDQPPLMITQYHFTSWPDHGVPEYATSILQFHRRI
.|..... |||.|.| |. ||..|||. . . || . ..|.... |.|.. ||. | .. | ||||....|||||||| .. .|.. | .
elvyenktstivmltelveggktkCeeYWPdadkpknyGsvtvtlveskeledfvlrkllle...kkkteleitqyqylaWpdhgvPeskapllellrqv
KNEYKPTKGPMLVHCSAGVGRTGTFMAIDMGLQQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLE
|. . ||..|||||||||||||.|.|. ... |.| ||......|.|.||. .||| ||.|. ...|.
kvanqadtgpiivhCsaGvGrtgtFialdalidaveeedyiDvagtvaklRkqRallvqtlkqYefiyevlls
|
|||||||||
DSPc_SM00195 | 1033-1292 | 7.1e-84 | 276.6 | In-house | 2-261 (263) | alignment | |||
Range on Protein: 1033-1292
Range on HMM: 2-261/263.0
FKNQYCTLNSGDNEHSVTIAVTPSNRPLNRFGNIVVYDDNRILLNQIPGNtdCQNDYINACYIDGYSQDYKYIATQGPVTKTLVDFWRLIWQERPPVIVM
.|... .|.. ......| | ..|. ||. ||..||..|. |...... ..||||| ||.|.... |||||||| .|. ||||..|.|. ..|||
lkeefekleestspketteaekkknksknRyknilpydhtrVklkkeekk..egsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivm
VTNLKEDTTIKCHQYWPEH--GSTSYGPFRIELTKEQVLT-DYTIRKMQLTLLGSdQPPLMITQYHFTSWPDHGVPEYATSILQFHRRIKNEYKPTKGPM
.|. .|. .||..|||| |.. .| ....|.... ....|...|| | . . .|||....|||||||. ..|.|.. | .|.... ..||.
lteeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegk.eetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpi
LVHCSAGVGRTGTFMAIDMGLQQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLES
.|||||||||||||..||. |.. |.| .|| .|....|.||..|||| .||.|. .|.||
vVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeailey
|
|||||||||
PTPc_SM00194 | 1033-1292 | 7.1e-84 | 276.6 | In-house | 2-261 (263) | alignment | |||
Range on Protein: 1033-1292
Range on HMM: 2-261/263.0
FKNQYCTLNSGDNEHSVTIAVTPSNRPLNRFGNIVVYDDNRILLNQIPGNtdCQNDYINACYIDGYSQDYKYIATQGPVTKTLVDFWRLIWQERPPVIVM
.|... .|.. ......| | ..|. ||. ||..||..|. |...... ..||||| ||.|.... |||||||| .|. ||||..|.|. ..|||
lkeefekleestspketteaekkknksknRyknilpydhtrVklkkeekk..egsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivm
VTNLKEDTTIKCHQYWPEH--GSTSYGPFRIELTKEQVLT-DYTIRKMQLTLLGSdQPPLMITQYHFTSWPDHGVPEYATSILQFHRRIKNEYKPTKGPM
.|. .|. .||..|||| |.. .| ....|.... ....|...|| | . . .|||....|||||||. ..|.|.. | .|.... ..||.
lteeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegk.eetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpi
LVHCSAGVGRTGTFMAIDMGLQQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLES
.|||||||||||||..||. |.. |.| .|| .|....|.||..|||| .||.|. .|.||
vVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeailey
|
|||||||||
subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 1026-1293 | 4.2e-82 | 270.4 | In-house | 10-276 (281) | alignment | ||
Range on Protein: 1026-1293
Range on HMM: 10-276/281.0
HAKGNEGFKNQYCTLNSGDNEHSVTIAVTPSNRPLNRFGNIVVYDDNRILLNQIPGNTdcQNDYINACYIDGYSQDYKYIATQGPVTKTLVDFWRLIWQE
... |.||...| .|.. ..... | . .. |. ||. ||| || |. ... |. ..||||| ...||... .|||||||| ..||.||...|..
sqndnaGfieeyeklaaigvdntataskadenvlknrYsnivaYDatrvkvtpneenk..ntDYinanfvpgykgekeyiatqgPvPaslvafWqmvweq
RPPVIVMVTNLKEDTTIKCHQYWPEHG-STSYGPFRIELTKEQVLTDYTIRKMQLtlLGSDQPPLMITQYHFTSWPDHGVPEYATSILQFHRRIK-NEYK
. .|||||. | .|||.|||.. ...|| .... |.|. . | ||..| .. .. ..| ..|.|||||||. .. .|.|.. .. . |
kvsaivmvtreieagklkChrYWPddnselkygdvtvkstaeeekatyierkfkl..eresgetreveqlaytaWPdhGvPattkellefrkevlkltek
PTKGPMLVHCSAGVGRTGTFMAIDMGLQQAEKE-GGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLESV
|| |...|||||||||||..|.| ....|.| .|. .....|..|. |||| || || |||. .
ktkaplvihCsaGvGrtGtyialDrlvkaveaeleeldvkavvaelrkernlmvqtvvqyefvykavldal
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 1057-1291 | 5.8e-82 | 270.0 | Pfam-A | 1-235 (235) | alignment | ||
Range on Protein: 1057-1291
Range on HMM: 1-235/235.0
NRPLNRFGNIVVYDDNRILLnqipgNTDCQ-NDYINACYIDGYSQDYKYIATQGPVTKTLVDFWRLIWQERPPVIVMVTNLKEDTTIKCHQYWP--EHGS
|. ||. .|..||..|. | . ... .||||| |..||... |.||||||. .|. ||||..|||. ||||.|.|.| ||.|||| |..|
nkkknRykdilpydktrvkl.....kgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeees
TSYGPFRIELT-KEQ-VLTDYTIRKMQLTLLGSDQPPLMITQYHFTSWPDHGVPEYATSILQFHRRIKNEYKPTKGPMLVHCSAGVGRTGTFMAIDMGLQ
..|| ...||. ||. ..||.||..|. .... . ...|.|.|.|||||||| ..|.|.. |..... ....||..|||||||||||||.|.|. |.
ltygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldille
QAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLE
|.|.|. .|. .|....|.||..|||...||||. .|.||
qleaeeevdvlqivkelRkqRpgmvqsleqYiflykaile
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 1057-1291 | 5.8e-82 | 270.0 | In-house | 1-235 (235) | alignment | ||
Range on Protein: 1057-1291
Range on HMM: 1-235/235.0
NRPLNRFGNIVVYDDNRILLnqipgNTDCQ-NDYINACYIDGYSQDYKYIATQGPVTKTLVDFWRLIWQERPPVIVMVTNLKEDTTIKCHQYWP--EHGS
|. ||. .|..||..|. | . ... .||||| |..||... |.||||||. .|. ||||..|||. ||||.|.|.| ||.|||| |..|
nkkknRykdilpydktrvkl.....kgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeees
TSYGPFRIELT-KEQ-VLTDYTIRKMQLTLLGSDQPPLMITQYHFTSWPDHGVPEYATSILQFHRRIKNEYKPTKGPMLVHCSAGVGRTGTFMAIDMGLQ
..|| ...||. ||. ..||.||..|. .... . ...|.|.|.|||||||| ..|.|.. |..... ....||..|||||||||||||.|.|. |.
ltygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldille
QAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLE
|.|.|. .|. .|....|.||..|||...||||. .|.||
qleaeeevdvlqivkelRkqRpgmvqsleqYiflykaile
|
|||||||||
subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 1028-1298 | 8.6e-82 | 269.2 | In-house | 12-298 (301) | alignment | ||
Range on Protein: 1028-1298
Range on HMM: 12-298/301.0
KGNEGFKNQYCTLNSGDnEHSVTIAVTPSNRPLNRFGNIVVYDDNRILLNQIPGNTDCQNDYINACYIDGYSQDYKYIATQGPVTKTLVDFWRLIWQERP
| ...|..|| .|..|. ..| |. .. .|..|||| ||.|||||||.|.. | . ||..|||| ||||||. |.||.|||. |||||||||||||.|
khsnkfeeqykelkege.dksctvglseenkalnrfknitvyddnriilkpkpnldlcqreyinasyidgysekkkfiaaqgpmkktlvdfWrliwqekp
PVIVMVTNLKEDTTIKCHQYWPE--HGSTSYGPFRIELTKEQVLTDYTIRKMQLTLL--------------GSDQPPLMITQYHFTSWPDHGV-PEYATS
|||||||||.| ||.||||. . |...||| ..|..|||. |..||...... ||. . ..|.. |.||..|| .|..|
vsivmvtnlkegtkskceqywpnseaeseefgpftvtlvneqvyPdfvirqlnvkiqdgsnngyierkfkvksdksswdvlqlqvtdWpqdGvvreprtv
ILQFHRRIKNEYKPTKGPMLVHCSAGVGRTGTFMAIDMGLQQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLESVTCGNT
. . |. . |. .||..||||..|.|.|.......|| |. || .|.. ... .|......|.| .||... |.. . ... .|
LqviddvihrqqkigggpvvVHCSdtVsrsGvYcsvsiglEQckaegVVdvfqvtkavrrskpgaVtTLeqytsiydvidmylqlnst
|
|||||||||
subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 1012-1328 | 9.7e-81 | 266.1 | In-house | 5-314 (315) | alignment | ||
Range on Protein: 1012-1328
Range on HMM: 5-314/315.0
LIPVGQFGEFVANGHAKGNEGFKNQYCTLNSGdNEHSVTIAVTPSNRPLNRFGNIVVYDDNRILLNQIpgNTDCQNDYINACYIDGYSQDYKYIATQGPV
||. |. .||. .| ..|||..| .. | . | . .| |. ||. ||. || |. | . ..| . ||.|| .||||.. .|||.|||
pipldqlityvaqkkastkngfkqdyesipgg.qlhpldvakkienkqknryiniiaydksrvqlpll..endphsdyvnanfidGynkkrryiaaqgpn
TKTLVDFWRLIWQERPPVIVMVTNLKEDTTIKCHQYWPEHgSTSYGPFRIELTKEQVLTDYTIRKMQLTlLGSDqpPLMITQYHFTSWPDHGVPEYATSI
. .. |||||...| |||.||| |. |. .|||.. ||.. . . .|.| |.||.| . . |.. . |.|.||||| |||.|....
vasvkdfwrlvfeedigkivmltnlvegekrkaekywpdk.kviyGkitvtrkseevnteytvrtlsvv.fgdn..irevvqlhytswpdmgvpkytipl
LQFHRRIKNEYKPTKGPMLVHCSAGVGRTGTFMAIDMGLQQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLESVTCGNTQVDSRNARIVFNR
....|..| . . |...|||||||||||||...| |.||| | ||. .|...||.|.||||.|.|| |. ||.||.. ||.| . . ..
mnlirtvkqhhtnsvgaivvhcsaGvGrtGtfitldavldqaeaenaidvynfitgvrqnrikmvqvaeqyqfiydalletfvcgdtsiaqdlylqryds
MSKPDTKTGRTGFIDQF
. | || | . .||
llapspdtgstllqeqf
|
|||||||||
subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 1051-1296 | 6.9e-80 | 262.9 | In-house | 3-245 (250) | alignment | ||
Range on Protein: 1051-1296
Range on HMM: 3-245/250.0
IAVTPSNRPLNRFGNIVVYDDNRILLNQIPgnTDCQNDYINACYIDGYSQDYKYIATQGPVTKTLVDFWRLIWQERPPVIVMVTNLKEDTTIkCHQYWPE
.| |.|. ||. .|. .| |..|.. .| . ||||| ...||.. .||||||...|..||||....| .|||.||||| .|||||
vakkpqnkeknryadiialdssrvvLekek..gdkesdyinasflhgyderkafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqywPv
HGSTSYGPFRIELTKEQVLTDYTIRKMQLTLLgSDQPPLMITQYHFTSWPDHGVPEYATSILQFHRRIKNEYKP-TKGPMLVHCSAGVGRTGTFMAIDMG
... || ...| .... .|||.||..|. . . .. |.||..||| ||||.||..|.. .... . . ..|..|.|||||||.|.|.|||
ekaekyGdvtvsllskeefadytkrklklska.kkaderivrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidav
LQQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLESVTCG
|....|| .|. .|...|..|...|.. .||.|| ..|. ...
lerlkkekvvdvfkvikvlrkdrphavesleqyvfvyeiilkaldsv
|
|||||||||
0045098 | (Phosphotyrosine protein) phosphatases II | 1045-1295 | 9.5e-80 | 263.2 | In-house | 21-274 (278) | alignment | ||
Range on Protein: 1045-1295
Range on HMM: 21-274/278.0
NEHSVTIAVTPSNRPLNRFGNIVVYDDNRILlnqipgntdcqnDYINACYIDGYsqDYKYIATQGPVTKTLVDFWRLIWQERPPVIVMVTNLKEDTTIKC
. ..| |. ..|...||. .|. || .|. ||||| ||||| . |.|||||| .|. ||||..|... .||||.|.|.|.. .||
ipseitpalylgnldknRykdilpydhsrVk............dYINAsyidgy..pkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekc
HQYWPEHGSTSYGPFRIELTKEQVLTDYTIRKMQLTLL---GSDQPPLMITQYHFTSWPDHGVPEYA--TSILQFHRRIKNEYK-------------PTK
.|||||.|| ||.|...|..|.|| |||.|.. .| | .| ... .|..|...|||||||.. .|.|.. ..|.. .| . .
aqywpeggsltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsg
GPMLVHCSAGVGRTGTFMAIDMGLQQAekEGGIDIISIINKMRQQRMK-MVQTADQYIFVNDAVLESVTC
||.|||||||||||||. |... |.. |||.|. ......|.||. .||. .||.|. ...|| . .
gpvlVHCsaGvgRtGtlvaaylmlell..eggvdlleavkelrsqRpglavqnleqyrflyefllelllr
|
|||||||||
0040439 | (Phosphotyrosine protein) phosphatases II | 1049-1291 | 2e-79 | 262.0 | In-house | 3-244 (249) | alignment | ||
Range on Protein: 1049-1291
Range on HMM: 3-244/249.0
VTIAVTPSNRPLNRFGNIVVYDDNRILLNQIPGntDCQNDYINACYIDGYSQDYKYIATQGPVTKTLVDFWRLIWQERPPVIVMVTNLKEDTTIKCHQYW
...| | |...||. .|. || .|. |. .|| .||||| ||||| . ..|||||| ..|. ||||..|... ||||.|.|.| .||.|||
ysvallpenkdknrypdilpydhsrvklsilpg..lflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqyw
PEHGSTSYGPFRIELTKEQVLTDYTIRKMQLTLLgSDQPPLMITQYHFTSWPDHGVPEYATSILQFHRRIKNEYK--PTKGPMLVHCSAGVGRTGTFMAI
|. ||. || |...|....|. |||.|...|| | |...........|.|||||||.. ..|.| ..... .. |..||.|||||||||||||| |.
plggsleygdftvtllsvevkddytvrtleltnl.ydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaa
DMGLQQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLE
.. |.| |||.|.|. ......|.||...||. .||.|. .|.||
ylmleqlekelgvdleeavkllrsqRpgavqnpeqyrflyealle
|
|||||||||
0042113 | (Phosphotyrosine protein) phosphatases II | 1050-1291 | 5.5e-79 | 260.3 | In-house | 2-241 (245) | alignment | ||
Range on Protein: 1050-1291
Range on HMM: 2-241/245.0
TIAVTPSNRPLNRFGNIVVYDDNRILLNQIPGntDCQNDYINACYIDGYSQDYKYIATQGPVTKTLVDFWRLIWQERPPVIVMVTNLKEDTTIKCHQYWP
..| | |...||. .|. ||..|. |. ..| | .|||||.|.||| . |.|||||| ..|. ||||..|... .|||.|.. |. .||.||||
svallpenkdknrysdilpydhtrvklspdgg..dldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywp
EHGSTSYGPFRIELTKEQVLTDYTIRKMQLTLLgSDQPPLMITQYHFTSWPDHGVPEYATSILQFHRRIKNEYK-PTKGPMLVHCSAGVGRTGTFMAIDM
...|. || |...|..|..| |||.|....| | | .......||...|||||||.. ..|.|...... .. . .||.||||||||||||||.|...
lgesltygdftvtllseehlddytvrtlevtnl.gddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaayl
GLQQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLE
|.|.|||.|... ... ..|.||...||| .||.|. .|.||
mleqlekelgvsleeavkelrsqRpgavqtpsqyrflyealle
|
|||||||||
subfamily_Ptp69D_pd | Subfamily Ptp69D | 1018-1309 | 2.1e-77 | 255.3 | In-house | 9-302 (307) | alignment | ||
Range on Protein: 1018-1309
Range on HMM: 9-302/307.0
FGEFVANGHAKGNEGFKNQYCTLNSGDNEHSVTIAVTPSNRPLNRFGNIVVYDDNRILLNQIPGNTDcqNDYINACYIDGYSQDYKYIATQGPVTKTLVD
| . . . . ..|... | .|.. ..| ... | ||. .|. .|..|. |..|.|. | ||||| .| || . |.|| |.|| |. |
leealksrkrdtdfglakeyekLeareidkstkvsekkenalknRyedikafDktRvkLkkingked..sdYinasfikgykekkkfiaaqdPveatigD
FWRLIWQERPPVIVMVTNLKEDTTIKCHQYWPEHGSTSYGPFRIELTKEQVLTDYTIRKMQLTLLGSDQ----PPLMITQYHFTSWPDHGVPEYATSILQ
|||.|.. .|||..||.| . ||..|||. . || ..| .|. .||.||..... . . ..|||.|.|.| ||| |...|.
fWRmiaeqevtlivmlsnlteknrkkcakYWpiedevqygdilvklvseekhsdyiiReldvskkkeesgevedsrkvvqyhytgWkDskvPevargllk
FHRRIKNEYKPTKGPMLVHCSAGVGRTGTFMAIDMGLQQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLESVTCGNTQVDSRNARIVF
. ..... || ..|..|||||||||.|.|.|.|. ||| ..| .||. .. ..|.|| .|| .||.|. |.|. . |.|..| .. .
lieqvrelyklnrsPivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnllvqsleqYvflyralldyssygdtdedvddledai
|
|||||||||
subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 1013-1300 | 1.7e-76 | 252.1 | In-house | 3-284 (315) | alignment | ||
Range on Protein: 1013-1300
Range on HMM: 3-284/315.0
IPVGQFGEFVANGhaKGNEGFKNQYCTLNSGDNeHSVTIAVTPSNRPLNRFGNIVVYDDNRILLNQIpgNTDCQNDYINACYIDGYSQDYKYIATQGPVT
||| || || . . | ... | | . ..| .. | . ||..||. .| .|. |. | . . ..||||| || .. .| |||.|||
ipvaqfpafvnkn..rhtalfseefhdlpdPdi.yrqrvaretinfkknryknilPldsarvklevi..ddsPdsdyinasyiksvdddkayiasqgPlk
KTLVDFWRLIWQERPPVIVMVTNLKEDTTIKCHQYWPE--HGSTSYGPFRIELTKEQVLTDYTIRKMqLTLLGSDQppLMITQYHFTSWPDHGVPEYATS
.. ||||...||.. |||||...|. ||| ||||. |. .| ...|| . . || ..||. | . .. .||..|| |||.||.. ..|
asvddfwrmvlqekvttivmvtkkqegdkikcrqywPdrkadsvefGsikvellsleadtdgvarkl.vtrksees..rtvtqfqftewPdkGvdkqtss
ILQFHRRIKNEYKPTKGPMLVHCSAGVGRTGTFMAIDMGLQQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLESVTCGNTQV
.|.. . .| . .. . ..|||||||||||| ...|| ..|.... .|. .....|..|...||| ..| |. ||||| . || .
llklikevkadngkkefsllvhcsaGvGrtGvvisidevvaqikrtrsvdvfnfvknlrakrpylvqteeeyafiydavledllwrntli
|
|||||||||
subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 1013-1303 | 4.5e-75 | 247.7 | In-house | 2-286 (515) | alignment | ||
Range on Protein: 1013-1303
Range on HMM: 2-286/515.0
IPVGQFGEFVANGHAkgNEGFKNQYCTLnSGDNEHSVTIAVTPSNRPLNRFGNIVVYDDNRILLNQIPGNtdCQNDYINACYIDGYSQDYKYIATQGPVT
.|. || ||. | ... | | | . |.| | . ||..||. || .|. |. | | ..||.|| || .. | |||.|||
lplaqfPafvnknrh..ttlfseefhdl.pgpniypqtvaqeeinfkknryknilPydsvrvklevindn..PhsdyfnasyipsfdndkayiasqgPnk
KTLVDFWRLIWQERPPVIVMVTNLKEDTTIKCHQYWPE--HGSTSYGPFRIELTKEQVLTDYTIRKMQLTlLGSDqpPLMITQYHFTSWPDHGVPEYATS
.. |||||..||.. |.|||.|||. ||| .|||. | .| ...|| . |. ..||.... |.| .||.||| |||.|||. ..|
asvddfWrlvlqenvttiamvtklkegdkikcgkyWPdkpgdsvkfGsikvelvsleactggikrkltvl.kgdd..srtvtqfhfteWPdkGvpkhtss
ILQFHRRIKNEYKPTKGPMLVHCSAGVGRTGTFMAIDMGLQQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLESVTCGNTQVDSR
.|.. . .| . . |...|||||||||| ...|| . .|.. .|. .....||.|...||| .|| |. .|||| . || .
llklikevkadhgqythpliihcsaGvGrtGvvisidsvvahakttrmvdvfnfvtnirqkrpylvqtqeqyafiygavledllwrntlipvi
|
|||||||||
subfamily_PTPN6_pd | Subfamily PTPN6 | 1024-1294 | 1.1e-74 | 246.2 | In-house | 19-298 (306) | alignment | ||
Range on Protein: 1024-1294
Range on HMM: 19-298/306.0
NGHAKGNEGFKNQYCTLNSGDNEH--SVTIAVTPSNRPLNRFGNIVVYDDNRILLNqipGNTDCQNDYINACYIDGYS--QDYKYIATQGPVTKTLVDFW
... ....||.... .|. .... | . . |.|. ||. ||. .|..|. |. . ..||||| ||.. . .| .|||||| ...|. |||
eeeslekagfeeefeelqqeeakkllsrkegakpenkeknryknilPfDhtrvilk...epsvpgsdyinanyikkevkgsdksyiatqgclettvsdFW
RLIWQERPPVIVMVTNLKEDTTIKCHQYWPEHGS-TSYGPFRIELTKEQVLTDYTIRKMQLTLLGSDQPPLMITQYHFTSWPDHGVPEYATSILQFHRRI
|..||| ||||.|. | . || .|||.. . ..|| ... ..|. |.||..|..... ... . ||||.||||||||. .|.| . .
rmvwqensrvivmttkevErgkekCarYWPdeeekeeyGkisvtnvseksladYilRelsvskkkkkkeerevfqyhfksWPdhgvpkdpgavLdfledv
KNEYKPTK----GPMLVHCSAGVGRTGTFMAIDMGLQQAEKEG---GIDIISIINKMRQQRMKMVQTADQYIFVNDAVLESVT
..... .. ||..||||||.||||||. ||. |.. ||.| ||| ......|.|| .|||..|| || |. . .
nrkqeeleeaeagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqteqqykfvykaikkyie
|
|||||||||
subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 1026-1301 | 1.8e-74 | 245.1 | In-house | 4-274 (283) | alignment | ||
Range on Protein: 1026-1301
Range on HMM: 4-274/283.0
HAKGNEGFKNQYCTLNSGDNEhsVTIAVTPSNRPLNRFGNIVVYDDNRILLNQIPGntdcqnDYINACYID---GYSQDYKYIATQGPVTKTLVDFWRLI
....|. |.... |. | . ..||.. |.. ||. .||..| .|. |. . |||||..| | || |||..|.|. .| ||||...
rvnnnklfrevlkrlsvpdld..adiasadenkrknrnqeivpadqwrvelksesr......dyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmv
WQERPPVIVMVTNLKEDTTIKCHQYWPEHGSTSYGPFRIELTKEQVLTDYTIRKMQLTLLGSDQPPLMITQYHFTSWPDHGVPEYATSILQFHRRIKNEY
..|. |||.|.|.|| ||| ||||..|| ||.| . | || ..|... | .| . |... | . | . | |...| . | .
fdekitaivmltklqedlrikCsqyWPkrGsedyGeftvtlrkettsnsfiikelllrvnssakstlllahyqvidWleygeqaiinslvkfnkvislqt
KPTKGPMLVHCSAGVGRTGTFMAIDMGLQQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLESVTCGNTQVD
. |||..||||.|.|||..|.|. ...| | .|. .... ||.||| .||| ||| .| ..||| ||.||.
eskkgPivvhCstgiGrtavfiaasasvkdaltesvvdvfavvkimreqrmmavqtldqyklvhelvleqalcgdtqia
|
|||||||||
subfamily_PTPN12_pd | Subfamily PTPN12 | 1044-1294 | 8.5e-73 | 239.7 | In-house | 27-278 (290) | alignment | ||
Range on Protein: 1044-1294
Range on HMM: 27-278/290.0
DNEHSVTIAVTPSNRPLNRFGNIVVYDDNRILLNQIPGNTdcQNDYINACYIDGYSQDYKYIATQGPVTKTLVDFWRLIWQERPPVIVMVTNLKEDTTIK
....| . . ...|. ||. .|. || .|. |..| .. ..||||| .| | ... .|||.|||..||| ||||.||. . ..||. .. | .|
ekvysteagekeenvkknrykDilPydksrvelskieeee..gsdYinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkk
CHQYWPEHGSTS--YGPFRIELTKEQVLT-DYTIRKMQLTLLGSDQpplMITQYHFTSWPDHGVPEYATSILQFHRRIKNEYKPTKGPMLVHCSAGVGRT
|..||||.| .. .|.|...|..|. .. |..|| .... . . ...|.|.|.|||||||. |.|.|.. . ... . . |..||||||||||
CerYWpeegeeelefgefevtleeekavdddflirtLkveaqkesr...kvyqfhYtaWPDhgvPssaksllelielvrelqesedaPlvvhCsaGvGrt
GTFMAIDMGL---QQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLESVT
|| .|||. .. . .|. ... ..|.|| .||| .|| .| ||.| |.
Gtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelvq
|
|||||||||
0037934 | (Phosphotyrosine protein) phosphatases II | 1050-1291 | 1.3e-72 | 239.6 | In-house | 3-240 (243) | alignment | ||
Range on Protein: 1050-1291
Range on HMM: 3-240/243.0
TIAVTPSNRPLNRFGNIVVYDDNRILLnqipgnTDcqNDYINACYIDGYSqdyKYIATQGPVTKTLVD----FWRLIWQERPPVIVMVTNLKEDTTIKCH
.|| | |.. ||. .|. ||..|. | . .||||| .|... ..|||||| ..|. | |||..|... ||||.|.|.| . .||.
siallpenlsknrysdilpydhsrvkl......eg..sdyinanliyvtp...rliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekca
QYWPehGSTSYGPFRIELTKEQVLTDYTIRKMQLTLLGSDQPPLMITQYHFTSWPDHGVPEYATSILQFHRRIKNE--------YKPTKGPMLVHCSAGV
|||| |.. ||.|...|..|..| |||.|...|. |. |........||...|||||||. ...|.|.. ... . ...||.||||||||
qywp..gevtygdftvtllseehlddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGv
GRTGTFMAIDMGLQQAekegGIDIISIINKMRQQRMK-MVQTADQYIFVNDAVLE
|||||. |... |.. |.|. ......|.||. .||| .||.|. .|.||
gRtGtliaaylmllll....gvdleeavkllreqRpgkavqtpsqyrflyealle
|
|||||||||
0050432 | (Phosphotyrosine protein) phosphatases II | 1311-1587 | 5e-72 | 238.2 | In-house | 31-306 (308) | alignment | ||
Range on Protein: 1311-1587
Range on HMM: 31-306/308.0
RMSKPDTKTGRTGFIDQFTVLEQVTQrPDEVTHNIASQNNDKNRSTQFLPRDNYRVPLkGEHPDYINAVFINGY--KEKKAFIIAESPMFNTARNFWKMI
. . . ....... .| | .|. . | .. .| ||||.. .|| |. || | .|. ||||| ...|| | ...||.. .|. || .||.|.
llkllekaldlglleeefeellsvkp.lleysvallpenkdkNrykdilpydhsRVkl.degsdYInAsyvdgyssklprkfIatqgPlpntvedFwrmv
DDRNVTAIVMLCHEKEIDQEVCYQYWPST--PSGLVIGEYAIMLSSEEIYNGYIERKLEVKNTNTGSTQSVMQYQITNWVSTRKMAKPQTILSVIEEMYK
. ||. ||||. . | ..| |.||||.. . |..| . . | |||....|. |.||..|...| . |.... ||| .|. .|. .|.. |
weqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseevlddytvrtleltnlgdgesrtvthfhytnWpdhgvPpspeilldflelvrk
TQrrrGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYLDSFETYS
.. .. ||||||. |||.. |.|. . .. ..|| .|||...| | |.||.|||..||. .....| || ...|.
sl...pggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylflyralleylklkltkl
|
|||||||||
subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 1319-1585 | 1.6e-71 | 236.0 | In-house | 19-288 (305) | alignment | ||
Range on Protein: 1319-1585
Range on HMM: 19-288/305.0
TGRTGFIDQFTVLEQVtQRPDEVTHNIASQNNDKNRSTQFLPRDNYRVPLKGEHP--DYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAI
. .|. |. | . . . .|... |........... |. | ... | ... ||||| ...|||.||..|.| .|. || ..||..| . |. |
ysdkgleaqykslyee.eesidvgkkeankaknrlkeitlldddriiltekeslddsdyinasyvdgykrkkkyivaqgPlkntvadfWrliveekvsti
VMLCHEKEIDQEVCYQYWPSTPSG-LVIGEYAIMLSSEEIYNGYIERKLEVKN-TNTGSTQSVMQYQITNWVSTRKMAKPQTILSVIEEMYKTQRRRGNT
|||.. .| ... |.|||| . . .||. ..|.||. ...||||||.. . . ...|.|||.|.| .. ..||.|... |.|.. ..
vmltklveggkdkCrqYWpesktekkefgefsvelksektasdyieRklkisiededkesrtvlqyqltdWPdhGvpqfatsllslikrvqkdqkkdkgv
SIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYLDSFET
...||||..|||. .|.| ....|.|.|.|||.||| | .... ||| .||. ..... .. ...|
pllVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkmvqtldqYvflhdaldelitcgdt
|
|||||||||
subfamily_PTPN9_pd | Subfamily PTPN9 | 1020-1291 | 4.2e-71 | 234.4 | In-house | 5-288 (297) | alignment | ||
Range on Protein: 1020-1291
Range on HMM: 5-288/297.0
EFVANGHAKGNEGFKNQYCTLNSGDNEHSVTIAVTPSNRPLNRFGNIVVYDDNRILLNQIPGNTdcQNDYINACYIDGYSQDYKYIATQGPVTKTLVDFW
|.|| ..||..| ...| . . | .. . ...| ||. ... ||. |. |....... . ||||| ..||| | .||||||. || |||
elvayvkekgkrGlskeyaeirnepveGtflasklranleknrytdvlcydetrvvlakvdede..asdyinanfvdGykqkkafiatqGplkktvsdfW
RLIWQERPPVIVMVTNLKEDTTIKCHQYWP--EHGSTSYGPFRIELTKEQVLTDYTIRKMQLTLLGSDQPpLMITQYHFTSWPDHGVPEYATSILQFHRR
|..|... ||||.| . | .|| |||| |. |...| .... . .. ||..|..... .. .| . |.||||.|||. |.|.|.. .
rmvWeqevlvivmttrvvergrlkcgqyWpleeessaefgdlsvsnveveeeedykvrvleiknvktees.rkvthfqflsWPdyGvPssaaslldvlek
IKN-------------EYKPTKGPMLVHCSAGVGRTGTFMAIDMGLQQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLE
... ...|.. |..||||||.||||||...|. |.. |..| .|.. ....|.|| ..|| .|| | ||||
vrekqalavkelgdewkghpsgPPivvhcsaGiGrtGtfitldiclsrleevgtvdvvetvkllrtqrafsiqtpeqyefcylavle
|
|||||||||
subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 1296-1586 | 2e-70 | 232.4 | In-house | 1-296 (298) | alignment | ||
Range on Protein: 1296-1586
Range on HMM: 1-296/298.0
GNTQVDSRNARIVFNRMSKPDTKTGRTGFIDQFTVLEQVTQRPDEVTHNIA--SQNNDKNRSTQFLPRDNYRVPLKG----EHPDYINAVFINGYKEKKA
|||...... .. ...... . |.. ||. ..| |..|... .| ....| ..|..||| .. .. | || |. |. |||||.|...||...|
gnteieaedlkaalqklaavkkkkkltgyalefqrlnsvsseieeeekevarkpenkkkNRyadiialdssRvvLekedadeesdYiNAsflhaykgrna
FIIAESPMFNTARNFWKMIDDRNVTAIVMLCHEKEIDQEVCYQYWPSTPSGlVIGEYAIMLSSEEIYNGYIERKLEVKNTNTGSTQSVMQYQITNWVSTR
||... |. .| .||.|. ......|||| .| |. . .|||.. . || . | |.| . .| |||.|..... ....| | . |.| .
fiatqaPltetvedFWrmvteedigtiVmltnleeldktkyhkywPdegke.tygeitvsllskeefadlivrklkvskkkeekerevrqlhftsWpdkg
KMAKPQTILSVIEEMYKTQRRRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYLDSFETY
.. ...| ..... ..|.. ||....|.||. |||| |.| . ... |.| |.|||||.| |...||.||| .|| |...|| .||||...
vpenatsvldllrkvrasqqqagnkpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavlealdsfnde
|
|||||||||
subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 1041-1312 | 2.4e-70 | 232.4 | In-house | 45-310 (319) | alignment | ||
Range on Protein: 1041-1312
Range on HMM: 45-310/319.0
NSGDNEHSVTIAVTPSNRPLNRFGNIVVYDDNRILLNQIPGNTdcQNDYINACYIDGYSQDYKYIATQGPVTKTLVDFWRLIWQERPPVIVMVTnlkedt
. | | | | . |. ||..||. .| |.. |... | ||||| ...|| . ||||.||| || ||||.||. . ||..|
klgvnladqtfanldqnkdknriinilafdknvvklerliGee..fsdyinasfvtGyqrkdkyiaaqGPldntladfWrmiweyncstivllt......
TIKCHQYWPEHGSTSYGPFRIELTKEQVLTDYTIRKMQLTLLGSDQPPLMITQYHFTSWPDHGVPEYATSILQFHRRIKNE--YKPTKGPMLVHCSAGVG
|| |||| .. .. | .... . .|..|...|. | . |||.|| |||.|||.|.. .... .... . . ...||||||||
kdkcsqywplkivikeerfkvkvdsveetaeyvvrdielsedgkekdirkitqfhflGwpdvGvpdypsdlmrlvkkvrhltskenhranivvhcsaGvG
RTGTFMAIDMGLQQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLESVTCGNTQVDSRNARIVFNRM
|||.....|. |.. ..| .|. ... .|||| ..|| || |. |.|| |...| . ....
rtGvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleehlfghsdvampdfpayleel
|
|||||||||
subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 1057-1291 | 6.5e-70 | 230.0 | In-house | 7-238 (239) | alignment | ||
Range on Protein: 1057-1291
Range on HMM: 7-238/239.0
NRPLNRFGNIVVYDDNRILLNQIpgNTDCQNDYINACYIDGYSQDYK-YIATQGPVTKTLVDFWRLIWQERPPVIVMVTNLKEDTTIKCHQYWPEHGStS
|. ||. ||| || .|..|... . | ..||||| |. | | |||||| |. . ||||..|||| ||||.| | | |||||||. |
nkaknryanivtydhsrvvlekl..sndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdsts.k
YGPFRIELTKEQVLTDYTIRKMQLTLLGSDQPpLMITQYHFTSWPDHGVPEYATSILQFHRRIKNEYKPTKGPMLVHCSAGVGRTGTFMAIDMGLQQAEK
| .|. | | .|..|| || . .. .| . . ||||| |||.|||.|||..| ..|.| .. | | ..||||||||||.|. || |.||.|
ycnlrvtlrktevfadyiirtfvmsqvgqtee.ryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlrqakk
EGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLE
. .||. .. .|..| .||||..||.|. ||||
qktvdifnyvkairedrphmvqtseqyvfihlavle
|
|||||||||
subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 1041-1312 | 1.2e-69 | 229.9 | In-house | 9-274 (284) | alignment | ||
Range on Protein: 1041-1312
Range on HMM: 9-274/284.0
NSGDNEHSVTIAVTPSNRPLNRFGNIVVYDDNRILLNQIPGNTdcQNDYINACYIDGYSQDYKYIATQGPVTKTLVDFWRLIWQERPPVIVMVTnlkedt
. | | | | . |. ||.|.|. .| |.. |... |. ||||| .| || . |||||||| || ||||.||. . ||..|
klgvngtdqtfanldqnkdknrighilafdknvvklerliGee..fsdyinasfitGyqrkdkyiatqGPldntladfWrmiweyncstivllt......
TIKCHQYWPEHGSTSYGPFRIELTKEQVLTDYTIRKMQLTLLGSDQPPLMITQYHFTSWPDHGVPEYATSILQFHRRIKNE--YKPTKGPMLVHCSAGVG
|| |||| .. .. |..... . .|..|...|. | . |.|.|| |||.|||.|.. .... .... . . ...||||||||
kdkcsqywplkivikeerfkvkvdsveeseeyvvrdielsedgkekdirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagvg
RTGTFMAIDMGLQQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLESVTCGNTQVDSRNARIVFNRM
|||.....|. |.. ..| .|. .....|||| ..|| || |. |.|| |...| . ....
rtgvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleehlfghsdvalpdfpayleel
|
|||||||||
subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 1057-1291 | 1.2e-69 | 229.2 | In-house | 8-239 (239) | alignment | ||
Range on Protein: 1057-1291
Range on HMM: 8-239/239.0
NRPLNRFGNIVVYDDNRILLNQIpgNTDCQNDYINACYIDGYSQDYK-YIATQGPVTKTLVDFWRLIWQERPPVIVMVTNLKEDTTIKCHQYWPEHGStS
|. ||. ||| || .|..|... . | ..||||| |. | | |||||| |. . ||||..|||| ||||.| | | |||||||. |
nkaknryanivtydhsrvvlekl..sndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdsts.k
YGPFRIELTKEQVLTDYTIRKMQLTLLGSDQPpLMITQYHFTSWPDHGVPEYATSILQFHRRIKNEYKPTKGPMLVHCSAGVGRTGTFMAIDMGLQQAEK
| .|. | | .|..|| || . .. .| . . ||||| |||.|||.|||..| ..|.| .. | | ..||||||||||.|. || |.||.|
ycnlrvtlrktevfadyiirtfvmsqvgqtee.ryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlrqakk
EGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLE
. .||. .. .|..| .||||..||.|. ||||
qktvdifnyvkairedrphmvqtseqyvfihlavle
|
|||||||||
0047943 | (Phosphotyrosine protein) phosphatases II | 1316-1580 | 4.1e-69 | 228.4 | In-house | 6-272 (273) | alignment | ||
Range on Protein: 1316-1580
Range on HMM: 6-272/273.0
DTKTGRTGFIDQFTVLEQVTQrPDEVTHNIASQNNDKNRSTQFLPRDNYRVPLKGEHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTA
....|.|... .| | ... . . .. . .| ||||.. .|| |. || |.... ||||| ...||. |..||... |. || .||.|. . ||.
ekllgltllleefelllslkp.lltysvallpenkdknrykdilpydhsrvklgdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvweqnvrv
IVMLCHEKEIDQEVCYQYWPSTPS--GLVIGEYAIMLSSEEIYNGYIERKLEVKNTNTGSTQSVMQYQITNWVSTRKMAKPQTILSVIEEMYKTQRRR-G
||||. . | ..| |.||||.. |. |.. . | |||....|. |.||..|..|| . |.... |.| . .. .|. ||.. |... .
iVmLtelvelgrekcaqYwpleggelsltygkftvtllseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvrkalealps
NTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYL
|. .|||||. |||...|.|. . .. ..|| .||....| | |.||.|||..||. . ...| ||
ngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyealleyl
|
|||||||||
0051299 | (Phosphotyrosine protein) phosphatases II | 1313-1580 | 4.2e-69 | 228.5 | In-house | 18-286 (288) | alignment | ||
Range on Protein: 1313-1580
Range on HMM: 18-286/288.0
SkpdtKTGRTGFIDQFTVLEQVTQRpDEVTHNIASQNNDKNRSTQFLPRDNYRVPLKG----EHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMI
..| ||....| | ... .... . .| .|||.. .|| |. || |. |. ||||| .|.||. |..||... |. || .||.|.
l....angltglleefeellsllpd.ltlsaallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyidgynlkrkfIatqgPlpntvedFWrmv
DDRNVTAIVMLCHEKEIDQEVCYQYWPStPSGLVIGEYAIMLSSEEIYNGYIERKLEVKNT----NTGSTQSVMQYQITNWVSTRKMAKPQTILSVIEEM
. ||. ||||. . | ..| |.||||. . |..|.. . | |||....|. |.|||.|. .| .. |.... ||| |. .|. ....
weqnvrvIvmltklvelgrekcaqYwpl.ggsltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdspellldflrlv
YKTQRrRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYL
.| .. |. .|||||. |||...|.|. . .. ..||..||....| | |.||.|||..||. .....| ||
rkala.sgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyealleyl
|
|||||||||
0036941 | (Phosphotyrosine protein) phosphatases II | 1318-1586 | 1.9e-68 | 226.3 | In-house | 9-283 (297) | alignment | ||
Range on Protein: 1318-1586
Range on HMM: 9-283/297.0
KTGRTGFIDQFTVLEQVTQrPDEVTHNIASQNNDKNRSTQFLPRDNYRVPLKGEHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIV
....... .| | .. . . .. . .| .|||.. .|| |. || |..|. ||||| ...||. |..||... |. || .||.|. . ||| ||
llflalllkefeellplll.lgslsvallpenleknRykdilpydhtRVklddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqnvtvIv
MLCHEKEIDQEVCYQYWPST-PSGLVIGEYAIMLSSEEI--YNGYIERKLEVKNTNTGSTQSVMQYQITNWVSTRKMAKPQTILSVIEEMYKTQRRR-GN
||. . | . | |.||||.. .. |. |.. . | |.|. ...|. |.|||..|..| . |.....|.| |...|. ||.. | .. ..
mltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrkvlkllpsg
TSIVVHCSDTVGRSAMFCAAATTINKCK---TEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYLDSFETY
. ..||||. ||||..|.|| . .. . .|| .|.....|. | |.||.|||..||. . ...| .| ...|.
gpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallellkkkltk
|
|||||||||
0046845 | (Phosphotyrosine protein) phosphatases II | 1324-1588 | 2.4e-68 | 225.9 | In-house | 2-282 (284) | alignment | ||
Range on Protein: 1324-1588
Range on HMM: 2-282/284.0
FIDQFTVLEQVTQRPD-EVTHNIASQNNDKNRSTQFLPRDNYRVPLKG-----EHPDYINAVFINGY-----KEKKAFIIAESPMFNTARNFWKMIDDRN
....| | ..| . .... .. .| .|||....|| |. || || |. ||||| ...|| . ||.||.. |. || .||.|. . |
leeefeellsltvklllslsvallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqn
VTAIVMLCHEKEIDQEVCYQYWPSTPSGLVIGEYAIMLSSEEIYNGYIERKLEVKNTN-TGSTQSVMQYQITNWVSTRKMAKPQTILSVIEEMYKTQRR-
|. ||||. . | ..| |.||||.. . |..|.. . | |||....|. |.||..|.. || . |.....|.| . |. .|. .... . ...
vrvIVmltelvengrekcaqYwplegevltygdftvtllseevkddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrellenl
RGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEG---VIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYLDSFETYSN
|. ||||||. |||...|.|. . .. ..|| ..||....| | |.||.|||..||. .....| || .. |. .
pgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleylklkltlle
|
|||||||||
subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 1056-1291 | 2.7e-68 | 224.7 | In-house | 2-237 (237) | alignment | ||
Range on Protein: 1056-1291
Range on HMM: 2-237/237.0
SNRPLNRFGNIVVYDDNRILLNQIPGNtdcqNDYINACYIDGYSQ-DYKYIATQGPVTKTLVDFWRLIWQERPPVIVMVTNLKEDTTIKCHQYWPEHG-S
|. ||.||||.|| .|..|. .. |||||.|..|. ||||.|||. . |||...|||. ||||.| | | .|||.|||.
enkiknrygnivaydhsrvvlkgagsg....sdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpstdqp
TSYGPFRIELTKEQVLTDYTIRKMQLTLLGSDQPPLMITQYHFTSWPDHGVPEYATSILQFHRRIKNEYK--PTKGPMLVHCSAGVGRTGTFMAIDMGLQ
..|| . . |.|.. ..|||.| . |. .. . .| ||.||||||.|||......|.| ..| |. . . || ..|||||||||| |. || |.
aaygvltvslkkkeefsdytvrslllskrltlkevrlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlr
QAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLE
||... .|| . . ..| ..|| |||.|.....||
qakekkvvdiynyvysieedrpyiiqtkdqyvfihqtile
|
|||||||||
subfamily_PTPN3_pd | Subfamily PTPN3 | 1036-1291 | 5.4e-68 | 223.9 | In-house | 20-273 (280) | alignment | ||
Range on Protein: 1036-1291
Range on HMM: 20-273/280.0
QYCTLNSGDNEHSVTIAVTPSNRPLNRFGNIVVYDDNRILLNQipgntdCQNDYINACYID----GYSQDYKYIATQGPVTKTLVDFWRLIWQERPPVIV
|. .| ... ....| | | . ||. .|. ||. |. |.. ..||||| |.. . .. .|||||||..|| |||...|... .||
qfeqlyrkkpglaisaarkpenlsknryrdilpydatrvklke......setdyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqkssliv
MVTNLKEDTTIKCHQYWPEHG-STSYGPFRIELTKEQVLTDYTIRKMQLTLLGSDQpPLMITQYHFTSWPDHGVPEYATSILQFHRRIKNEYKPTKGPML
|.|.| |. .||||||||.. ...|| |.....||. . | .|.. |. ... .|.| ...|||||||. ....|.| .|... . .. |..
mlttlverGrvkChqyWPetedeleygefsvkcekedetksyvlrelvlkdketke.erkilqlqylaWpdhgvPddsadflefvervrklrsgkeePvv
VHCSAGVGRTGTFMAIDMGLQQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLE
||||||.|||| ...... |. |.. . .. |. .||.||. .||||.|| || .|.|.
vhCsaGigrtGvlilletalalieaaepvypldivrtmrdqramlvqtasqykfvCeailk
|
|||||||||
subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 1056-1290 | 3.6e-67 | 221.4 | In-house | 27-265 (274) | alignment | ||
Range on Protein: 1056-1290
Range on HMM: 27-265/274.0
SNRPLNRFGNIVVYDDNRILLNQIPGNtDCQNDYINACYIDGYSQDYK-YIATQGPVTKTLVDFWRLIWQERPPVIVMVTNLKEDTTIKCHQYWPEHGST
. ||. .|. . |.||.. .. | . .|||| || ||... | |.|||||...|. ||||.|.||. .||||.|.||| ||..|.|.. ..
gsqtknryktilPnensrvllesesse.dedssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneqkCavyfPdaedy
----SYGPFRIELTKEQVLTDYTIRKMQLTLLGSDQPplmITQYHFTSWPDHGVPEYATSILQFHRRIKNE---YKPTKGPMLVHCSAGVGRTGTFMAID
|| . |. .| ||..||. | | . . .. | .|.|||| .|. |...|.. . .... . .|..||||||.|||| |.||.
eiserygdveikvekiverndysvrklvlkylerers...vkhywytdWPdhksPddantlldlvleveesreeenaklapvvvhCsaGiGrtGcfiais
MGLQQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVL
....| ..|. .|...|. ..|..| ||||..|| .. |.
iavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralc
|
|||||||||
subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 1011-1301 | 6.8e-67 | 220.7 | In-house | 8-292 (297) | alignment | ||
Range on Protein: 1011-1301
Range on HMM: 8-292/297.0
NLIPVGQFGEFVANGHAKGNEgFKNQYCTLNSgdNEHSVTIAVTPSNRPLNRFGNIVVYDDNRILLNQIpgNTDCQNDYINACYIDGYSQdyKYIATQGP
. ||. .| .| ... . .. |.... | .. | | | . .|. ||. || .|. |. . |.| . ||.|| .. |. . ..|.|| |
rpiplsdfatlvqknrhtdvf.seeflclpea..niqpqtvaekkvnfeksRYkniLPydssRvkLaiv..nddpdsDyvnasfvkgnkh..rlittqmP
VTKTLVDFWRLIWQERPPVIVMVTNLKEDTTiKCHQYWPEHGSTSYGPFRIELTKEQVLTDYTIRKMQLTLlGSDQPPLMITQYHFTSWPDHGVPE--YA
|. |||.....|.. .|||.....| . || .||...|.|..| ..|. . . . |....| |. . .. ||.|..|||. |.. |
mkatvadfWamvldeqvstivmlnddnerdk.kcaryWsdkgvttfGdvsvvllsvsereGfikrelevtk.gkakarrvvkqyqfveWPdkaverkdsa
TSILQFHRRIKNEYKPTKG-PMLVHCSAGVGRTGTFMAIDMGLQQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLESVTCGNTQVD
.|.|.. ...... .. |.||||.||||||| ...|| . .|..| .|| ...|.||.|...||| .|| || |||| . . .|...
ssllklisevrkdfsqnaegPllvhclaGvGrtgvlltidsvvaeakrekevdifglvkklrqerpylvqtkeqykfvyvavleallsedtriq
|
|||||||||
subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 1015-1302 | 3.2e-66 | 218.7 | In-house | 7-297 (325) | alignment | ||
Range on Protein: 1015-1302
Range on HMM: 7-297/325.0
VGQFGEFVANGHAKGNEGFKNQYCTLNSgDNEHSVTIAVTPSNRPLNRFGNIVVYDDNRILLNQIpgNTDCQNDYINACYIDGYSQDYKYIATQGPVTKT
| .. |.| . .|. ..|| ... | | |. . ..|. | |. ||| |.| .| .|. |. . | . ||||| |. . . ..|.| | |.|
vvnlvehvekkkaqdqdgfahefgllps.ddgiakkvamkpenkaknrfknvvaldksrvvletk..kddpssdyinasylrddkkkdvflaaqaPltat
LVDFWRLI--WQerPPVIVMvTNLKEDTTIKCHQYWPEH--GSTSYGPFRIELTKEQVLTDYTIRKMQLTLLgSDQPPLMITQYHFTSWPDHGVPEYATS
. |.|||. |. .|.|. .| . .| .|||.. | .|.....| . ..|| |.... .. . . |... ||.| ||... ..
indlWrlvldWr..csvvvv.lneldlgkdrcavywpkemgksktfGglevklrtieeisdyvhrvldvkqv.kkGetrsvkqfqlqswddmGvqkrpat
ILQFHRRIKNEY---KP---TKGPMLVHCSAGVGRTGTFMAIDMGLQQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLESVTCGNTQVDS
.. . . .|. . . .|.||||||||||||.|... |.. .| .|| ..|.|..| .||.|.||||.. .|. | . .|||.|
lisilqlvkavservtantkastpilvhcsaGvGrtGvfislysalakvieesrvdifgfvkklrkdrpsmvetvdqyiliyealveaymsgntdvpv
|
|||||||||
0040438 | (Phosphotyrosine protein) phosphatases II | 1322-1586 | 5.7e-66 | 218.3 | In-house | 18-282 (317) | alignment | ||
Range on Protein: 1322-1586
Range on HMM: 18-282/317.0
TGFIDQFTVLEQVtqRPDEVTHNIASQNNDKNRSTQFLPRDNYRVPLKGEH----PDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIV
|.. ..| | .. .|. .. . .| ||||.. .|| |. || |. . ||||| ...|...|..||.. .|. || .||.|. . .|| ||
talleefedllsl..kldtysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPlpntvedFwrmvweqgvtviv
MLCHEKEIDQEVCYQYWPStPSGLVIGEYAIMLSSEEIYNGYIERKLEVKNTNTGSTQSVMQYQITNWVSTRKMAKPQTILSVIEEMYKTQRrRGNTSIV
||....| ..| |.||||. . |..|.. . | ||| ..|.. |.|||...... . |.... |.| |...|. .|.. . .. .... ..
mLteleelgrekcaqYwpl.getltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavreale.dpggpvl
VHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYLDSFETY
||||. |||...|.|| . .. ...|| .||....| | |.||.||| .||. . ...| || ..|.
VHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleylkrkltl
|
|||||||||
subfamily_PTPRD_pd | Subfamily PTPRD | 1341-1586 | 2.3e-65 | 216.3 | In-house | 40-287 (564) | alignment | ||
Range on Protein: 1341-1586
Range on HMM: 40-287/564.0
VTHNIASQNNDKNRSTQFLPRDNYRVPLK----GEHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCHEKEIDQEVCYQYWPS
... ...| ||| . .. |. || |. | ||||| ||.||...||.| . |. .| ..||.|. ..|.. |||| . .| ... | .|||.
weaankpaNkaKNRyanivaYdhsRVvLskvegdegsDYINAsfidgyrkrkayIAtqgPlaetiedFWRmvweqnsstiVmltkleEkgkvkchkYWPe
TpSGLVIGEYAIMLSSEEIYNGYIERKLEVKNTNTGSTQSVMQYQITNWVSTRKMAKPQTILSVIEEMYKTQrRRGNTSIVVHCSDTVGRSAMFCAAATT
. . .||. . |..|| .. |. |....|.... ... | |.. |.| .. . .....|..|... ... .... |||||| |||. .|..
k.gtetygeltVtleeeeeladyeirtfklkkkkssesreVrqFhFtsWPdhgvpesatslLdlirkvraln.epdagPivVhCSaGVGRTGtfividam
INKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYLDSFETY
... |.|...|..|..| | |.. ||| .||. |....| .|....|
lerikeektvDiyqyvkalrkqRnamVqteeQYiFiheailealacgnte
|
|||||||||
0045450 | (Phosphotyrosine protein) phosphatases II | 1314-1580 | 4.4e-65 | 215.7 | In-house | 19-304 (307) | alignment | ||
Range on Protein: 1314-1580
Range on HMM: 19-304/307.0
KPDTKTGRTGFIDQFTVLEQVTQR-PDEVTHNIASQNNDKNRSTQFLPRDNYRVPLKG-----EHPDYINAVFI--------NGYKEKKAFIIAESPMFN
. ......||. .| | .|| . ..| .. .| ||||.. .|| |. || |. |. ||||| .. .||. |..||.. .|. .
llllldfltgllkefekllsvtvfllgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydlkrkfIatqgPlpe
TARNFWKMIDDRNVTAIVMLCHEKEIDQEVCYQYWPSTPSGLVIGEYAIMLSSEEIYNGYIERKLEVKNT-NTGSTQSVMQYQITNWVSTRKMAKPQTIL
| .||.|. . .||.||||....| ..| |.||||.. . |..|.. . | |||...||. |.|||... || . |.... |.| . ....|
tvedFwrmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfeell
SVIEEMYKTQRRR-GNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGV---IDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYL
. |||. | ... ... ..||||. |||...|.|| . . ..||. .|.....| | |.||.||. .||. . ...| .|
dfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeallell
|
|||||||||
subfamily_PTPN13_pd | Subfamily PTPN13 | 1037-1293 | 1.7e-64 | 212.8 | In-house | 17-269 (273) | alignment | ||
Range on Protein: 1037-1293
Range on HMM: 17-269/273.0
YCTLNSGDNEHSVTIAVTPSNRPLNRFGNIVVYDDNRILLNQIPGntdcqndYINACYIDGY--SQDYKYIATQGPVTKTLVDFWRLIWQERPPVIVMVT
. .|. ..... . .|. ||. |.. ||. |. |.. | |||| .| . |.|||.|||. .| |||...|. . ||.|||
fkelrelkpldtcevgkkkenkdknryrnvlPydetrvklgdegg.......yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamvt
NLKEDTTIKCHQYWPEHGS---TSYGPFRIELTKEQVLTDYTIRKMQLTLLGSDQPpLMITQYHFTSWPDHGVPEYATSILQFHRRIKNEYKpTKGPMLV
. ||. .|||.||||. . . .. ...|| | | | ....|..... . | . ... .|..||||||| |...||| ..... . .||..|
lekekgkvkchrywPesknkklkvsnrlevellkvqkldgfvvralavkdsesges.revahlnfvkwPdhgvPssaaellqfvaevrrlqt.dagPivv
HCSAGVGRTGTFMAIDMGLQQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLESV
|||||.||.||...||. |. |.. .|. |..|.|.|| .||| |||||| |.|| .
hcsaGiGrsGtlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykailevl
|
|||||||||
subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 1320-1588 | 2.5e-63 | 208.6 | In-house | 13-301 (301) | alignment | ||
Range on Protein: 1320-1588
Range on HMM: 13-301/301.0
GRTGFIDQFTVLEQVTQRPDEVTHNIASQNNDKNRSTQFLPRDNYRVPLK----GEHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTA
..| .|.. |....... .|... . .. ....... .. .. . | . .|||| .|.||.|||.||.|..|| .| ..||..| . ...
hsnkfeeqykelkegedksctvglseenkalnrfknitvyddnriilkpkpnldlcqreyinasyidgysekkkfiaaqgpmkktlvdfWrliwqekpvs
IVMLCHEKEIDQEVCYQYWPST-PSGLVIGEYAIMLSSEEIY-----------------NGYIERKLEVKNTNtgSTQSVMQYQITNWVSTRKMAKPQTI
|||.. .|| .. |.||||.. . |. ..|..| .| |||||||..||... |...|.|.|.|.| . |.|.
ivmvtnlkegtkskceqywpnseaeseefgpftvtlvneqvyPdfvirqlnvkiqdgsnngyierkfkvksdk..sswdvlqlqvtdWpqdGvvreprtv
LSVIEEMYKTQRRRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYLDSFETYSN
| ||... ..|.. | .||||||||.|| ..|. .. || |||.||||| |. | .||| |.| .|| |.... .|| .||.|
LqviddvihrqqkigggpvvVHCSdtVsrsGvYcsvsiglEQckaegVVdvfqvtkavrrskpgaVtTLeqytsiydvidmylqlnstyan
|
|||||||||
DSPc_SM00195 | 1326-1580 | 4.7e-63 | 208.3 | In-house | 4-262 (263) | alignment | |||
Range on Protein: 1326-1580
Range on HMM: 4-262/263.0
DQFTVLEQVTQRPdEVTHNIASQNNDKNRSTQFLPRDNYRVPLKGEH----PDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCH
.|. ||. |. |.|... ..|..|||....|| |. || || |. ||||| .|.|...||..|.. |. .| . ||.|. ...|. ||||.
eefekleestspk.etteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlte
EKEIDQEVCYQYWPSTP-SGLVIGEYAIMLSSEEIYN-GYIERKLEVKNTNTGSTQSVMQYQITNWVSTRKMAKPQTILSVIEEMYKTQRRRgNTSIVVH
|.| ..| |..|||.. . ..|.. . | ..|... .| |.||...... |..| |||..|| ... .|.......|.... .. ||||
eeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkksksts.sgpivVh
CSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYL
||. |||...|... . ..|...| .|.|...|. | |.||.||| .||. | ...| |.
CsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi
|
|||||||||
PTPc_SM00194 | 1326-1580 | 4.7e-63 | 208.3 | In-house | 4-262 (263) | alignment | |||
Range on Protein: 1326-1580
Range on HMM: 4-262/263.0
DQFTVLEQVTQRPdEVTHNIASQNNDKNRSTQFLPRDNYRVPLKGEH----PDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCH
.|. ||. |. |.|... ..|..|||....|| |. || || |. ||||| .|.|...||..|.. |. .| . ||.|. ...|. ||||.
eefekleestspk.etteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlte
EKEIDQEVCYQYWPSTP-SGLVIGEYAIMLSSEEIYN-GYIERKLEVKNTNTGSTQSVMQYQITNWVSTRKMAKPQTILSVIEEMYKTQRRRgNTSIVVH
|.| ..| |..|||.. . ..|.. . | ..|... .| |.||...... |..| |||..|| ... .|.......|.... .. ||||
eeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkksksts.sgpivVh
CSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYL
||. |||...|... . ..|...| .|.|...|. | |.||.||| .||. | ...| |.
CsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi
|
|||||||||
0039614 | (Phosphotyrosine protein) phosphatases II | 1315-1584 | 8.1e-63 | 208.0 | In-house | 25-293 (297) | alignment | ||
Range on Protein: 1315-1584
Range on HMM: 25-293/297.0
PDTKTGRTGFIDQFTVLEQVTQrpDeVTHNIASQNNDKNRSTQFLPRDNYRVPLKG-----EHPDYINAVFINGYKE-KKAFIIAESPMFNTARNFWKMI
......|... .| | ... | .. .| ||||.. .|| |. || ||. .. ||||| ...||. ...||.. |. .| .||.|.
lekansktllllefeellslkp..d.ysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIatqgPlpetvedFwrmv
DDRNVTAIVMLCHEKEIDQeVCYQYWPSTPSglVIGEYAIMLSSEEIYNGYIERKLEVKNtnTGSTQSVMQYQITNWVSTRKMAKPQTILSVIEEMYKTQ
. .||.||||. ..| .. |.||||.. . . |.. . | ..| ..||. |.|||.| .| . |...| |.| ....|...|.. . .
weqgvtvivmLtklvelgr.kcaqywpeegg..tygdftvtllkvehldgytvrtlevtn..ngesrtvthfqytgwpdhgvppslellleflelvreal
RRR-GNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYLDSFE
.. ... ..||||. |||...|.|| . .. ...|| .||....| | |.||.||| .||. .....| .| .
aelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydallellkrkl
|
|||||||||
0043336 | (Phosphotyrosine protein) phosphatases II | 1318-1580 | 3.4e-62 | 205.7 | In-house | 16-277 (278) | alignment | ||
Range on Protein: 1318-1580
Range on HMM: 16-277/278.0
KTGRTGFIDQFTVLEQVTQrpDEVTHNIASQNNDKNRSTQFLPRDNYRVPLKGEH----PDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNV
....|... .| | ... |. .. . .| ||||.. .|| |. || |. . ||||| ...||. ...||.. |. .| .||.|. . .|
lnlktllllefeellsfkl..dtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpetvedFwrmvwelgv
TAIVMLCHEKEIDQEVCYQYWPstPSGLVIGEYAIMLSSEEIYNGYIERKLEVKNTNTGSTQSVMQYQITNWVSTRKMAKPQTILSVIEEMYKTQRrRGN
| ||||. ..| ... |.|||| . |..|.. . | .|| ...|. |.|||.|. .| .. |..|. ..| ....|. .... . .. |
ttivmLtelvelgrvkcaqYwp..ggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldflkavreale.dsn
TSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYL
. ..||||. |||...|.|. . .. ..|| .|.....| | |.||.||| .||. .....| ||
gpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyealleyl
|
|||||||||
subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 1322-1578 | 3.6e-62 | 204.8 | In-house | 6-264 (283) | alignment | ||
Range on Protein: 1322-1578
Range on HMM: 6-264/283.0
TGFIDQFTVLEQVTQRPDEVTHNIASQNNDKNRSTQFLPRDNYRVPLKGEHPDYINAVFIN---GYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVM
... .. ||.... . ... . |..|. ||| . .| |..|| || | .|||||||| ||..| .||| ||. .| ..||||. |...|||||
nnnklfrevlkrlsvpdldadiasadenkrknrnqeivpadqwrvelksesrdyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekitaivm
LCHEKEIDQEVCYQYWPSTPSgLVIGEYAIMLSSEEIYNGYIERKLEVKNT-NTGSTQSVMQYQITNWVSTRKMAKPQTILsVIEEMYKTQRRRGNTSIV
| . .| .. | ||||. | ||... | | | .| ..| ... . || . ||. .|.. . | ... .. . |.. .. ||
ltklqedlrikCsqyWPkrGs.edyGeftvtlrkettsnsfiikelllrvnssakstlllahyqvidWleygeqaiinslv.kfnkvislqteskkgPiv
VHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLT
|||| ..||.|.|.||...... .|| |.|||.|.| | |... ||| .||. . ..||
vhCstgiGrtavfiaasasvkdaltesvvdvfavvkimreqrmmavqtldqyklvhelvle
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 1349-1577 | 4e-62 | 205.1 | Pfam-A | 1-234 (235) | alignment | ||
Range on Protein: 1349-1577
Range on HMM: 1-234/235.0
NNDKNRSTQFLPRDNYRVPL--KGEHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCHEKEIDQEVCYQYWP-STPSGLVIGE
| .|||....|| |. || | .... ||||| ...||||||.||... |. .| ||.|. ...|..||||....| ..| | |||| .. | |.
nkkknRykdilpydktrvklkgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesltygd
YAIMLS-SEE-IYNGYIERKLEVKNTNTGS-TQSVMQYQITNWVSTRKMAKPQTILSVIEEMYKTQrRRGNTSIVVHCSDTVGRSAMFCAAATTINKCKT
. . | .|. . ..|. ||||.|.... | ...|.|...||| ..|. .|..|... |.. . ....|||||. |||...|.|. . ......
ikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkveksk.eaksgpvvVhCsaGvgRtgtfvaldilleqlea
EGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVL
|. .||.|..|. | |.||.||...||. . ...|
eeevdvlqivkelRkqRpgmvqsleqYiflykail
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 1349-1577 | 4e-62 | 205.1 | In-house | 1-234 (235) | alignment | ||
Range on Protein: 1349-1577
Range on HMM: 1-234/235.0
NNDKNRSTQFLPRDNYRVPL--KGEHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCHEKEIDQEVCYQYWP-STPSGLVIGE
| .|||....|| |. || | .... ||||| ...||||||.||... |. .| ||.|. ...|..||||....| ..| | |||| .. | |.
nkkknRykdilpydktrvklkgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesltygd
YAIMLS-SEE-IYNGYIERKLEVKNTNTGS-TQSVMQYQITNWVSTRKMAKPQTILSVIEEMYKTQrRRGNTSIVVHCSDTVGRSAMFCAAATTINKCKT
. . | .|. . ..|. ||||.|.... | ...|.|...||| ..|. .|..|... |.. . ....|||||. |||...|.|. . ......
ikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkveksk.eaksgpvvVhCsaGvgRtgtfvaldilleqlea
EGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVL
|. .||.|..|. | |.||.||...||. . ...|
eeevdvlqivkelRkqRpgmvqsleqYiflykail
|
|||||||||
subfamily_PTPRN_pd | Subfamily PTPRN | 1028-1293 | 8.8e-62 | 203.5 | In-house | 26-292 (297) | alignment | ||
Range on Protein: 1028-1293
Range on HMM: 26-292/297.0
KGNEGFKNQYCTLNSGDNEHSVT-IAVTPSNRPLNRFGNIVVYDDNRILLNQIpgNTDCQNDYINACYI-DGYSQDYKYIATQGPVTKTLVDFWRLIWQE
| .. ..... .| . ..| |.. .| .. | || ... ||..|. |.. ... ..||||| | | . |||||||...|. |||...|..
knkdrlekewealcayeaepstkevakaeknvkknrskavlpydhsrvklkee..asaeksdyinasaildhdprapayiatqgplastvadfwqmvweq
RPPVIVMVTNLKEDTTIKCHQYWPEHGSTSYGPFRIELTKEQVLT-DYTIRKMQLTLLGSDQPpLMITQYHFTSWPDHGVPEYATSILQFHRRIKNEYKP
|||..|.|.|. . .|..|||..|| |. . ..| | . . || .| . | | ... .||.|| |||..||| | |.|.| |.. |.
GvvvivnltrleeegvkqckrywpdeGsevyhiyevhlvsehiwcddylvrsfylknlqtset.rtvtqfhflswpeegvPasaksllefrrkvnksyrG
TKGPMLVHCSAGVGRTGTFMAIDMGLQQAEKE-GGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLESV
|..||||.|.||||....||. |.. | |||.. ....|.|| ..|.| ||. |. || | |
rscpivvhcsdGaGrtGvyilidlvlnrllkGvkeidiaatlehlrdqrpglvktkdqfefaltavaeev
|
|||||||||
subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 1320-1588 | 3.5e-61 | 202.0 | In-house | 18-288 (318) | alignment | ||
Range on Protein: 1320-1588
Range on HMM: 18-288/318.0
GRTGFIDQFTVLEQVTQRPDEvTHNIASQNNDKNRSTQFLPRDNYRVPLKG----EHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTA
|.. . .. |..... . . .. . . |. ||| . |. |. || |. | ||||| .|.||..|||.| | .|. .| ..||.|. ..| .
Gelllseeyerlsrseetvts.lkslepvnkaknryanilaydhtrvkLqmlegeegsDyinanyidGyrrkkayiaaqaPlpetieDfWrmvWeqnsav
IVMLCHEKEIDQEVCYQYWPSTPSgLVIGEYAIMLSSEEIYNGYIERKLEVKNTNTGSTQSVMQYQITNWVSTRKMAKPQTILSVIEEMYKTQRRRGNTS
|||| .|.| .. . .|||| | .|. . |..| .. |. |...|..|.. ... | ||..|.| . ... ..|... . |.|.. |..
ivmltqeeergkakvhryWPskgs.rsygklvvelkeevelsdyvlrefkvtrteeeesrqvrqyhytsWpdegvpesgaslldlvrqvskaqqksgagp
IVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYLDSFETYSN
|||||| ||| .|.| . ... | |...||||. | | |.. ||| .||. |....| .| |..|. .
ivvhCsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqtedqyefiydvllealasgdtevd
|
|||||||||
subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 1018-1309 | 4.5e-61 | 201.6 | In-house | 7-295 (439) | alignment | ||
Range on Protein: 1018-1309
Range on HMM: 7-295/439.0
FGEFVANGHAKGNEGFKNQYCTLNSGDNE--HSVTIAVTPSNRPLNRFGNIVVYDDNRILLNQIPGNTdcQNDYINACYIDGYSQDYKYIATQGPVTKTL
| | | . . . .| ||. . ..|| . . ..| ... ||. ... .| |. |..||| . |||| ||.|| .| ||||||| .|
fqehvekldknkqeifkeifekinstspdyaciaslaaqeydqtknrykdvgafdhtrvtlqeipgvp..hshyinanyikGyyddklyiatqgpkkett
VDFWRLIWQERPPVIVMVTNLKEDTTikchqYWPEHGSTSYGPFRIELTKEQVLTDYTIRKMQLTL-LGSDQPPLMITQYHFTSWPDHGVPEYATSILQF
|||||..... |||.||| | ||| . . || . .. | .|.|| ... . . . |.|...|||. || |. .|.|
ddfwrlviekktvtivmltnlvesyk.....ywpsdaevcygdiavrvdrnielpnyvirgfkvfnerdttekertvlqfhyiawpdknvpaqashvldf
HRRIKN-EYKPTKGPMLVHCSAGVGRTGTFMAIDMGLQQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLESVTCGNTQVDSRNARIVF
| |. . | ||..|||||||||||| .|.|. |.| | .|| |.. .|.|| .|||. ||.|. .|||| . |.. | . . |
lrainsandkeeygpvvvhcsagvGrtGtiialdialeqlklenkvdikgivkvlrkqrkqmvqalcqyvfiynavledivyGdiavtidefkkef
|
|||||||||
subfamily_PTPN1_pd | Subfamily PTPN1 | 1033-1302 | 4.9e-61 | 201.0 | In-house | 8-282 (290) | alignment | ||
Range on Protein: 1033-1302
Range on HMM: 8-282/290.0
FKNQYCTLNSGDNEHSVTIAVTPSNRPLNRFGNIVVYDDNRILLNQipgntdCQNDYINACYIDGYSQDYKYIATQGPVTKTLVDFWRLIWQERPPVIVM
.|. | ... ...... | .|.||.|||. .. || || |.. .|||||| .. . .|| ||||...| ||...|... .||
ykeiyldirkeasdfptreaklpenrnlnryrdvspydhsrikler......adndyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskavvm
VTNLKEDTTIKCHQYWPEHGS---TSYG--PFRIELTKEQVLTDYTIRKMQLTLLGSDQPpLMITQYHFTSWPDHGVPEYATSILQFHRRIKNE--YKPT
. .. | .|||.||||.. . . ....| .|.. ||.|...|. | ... |...|.|.||| |||| .. |.| .... ..
lnkvvekeqikcaqywPqgeeekellledtklkvkliseerksyytvrllelenlktqet.reilhfhyttwpdfgvpespaaflkflfkvresGslssd
KGPMLVHCSAGVGRTGTFMAIDMGLQQAEKEGG---IDIISIINKMRQQRMKMVQTADQYIFVNDAVLESVT--CGNTQVDS
.|| ..|||||.||.|||. .| | . ||.. .|| . ..|..|. ..||||| | |.|| . |.. |..
vGpavihcsaGiGrsGtfclvdtclvliekkddlssvdikkvllelrkyrlGliqtadqlrfsylaileGakvikgdssvqk
|
|||||||||
subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 1048-1292 | 3.4e-60 | 198.3 | In-house | 11-263 (270) | alignment | ||
Range on Protein: 1048-1292
Range on HMM: 11-263/270.0
SVTIAVTPSNRPLNRFGNIVVYDDNRILLNQIpgNTDCQNDYINACYIDGYS-QDYKYIATQGPVTKTLVDFWRLIWQERPPVIVMVTNLKEDTTIKCHQ
. .. . .. |||. .|. |. |... ..| . |||| |. |.. .. ||||..||. || .|||.||.|. . |||.|.|.|. . || .
esdlpeaargkklnRyadiLPsPatRvrleel..eedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCer
YWPEHGST----SYGPFRIELTKEQVLTDYTIRKMQLTLLGSDQpPLMitQYHFTSWPDHGVPEYAT------SILQFHRRIKNEYKPT-KG-PMLVHCS
|||.. . ..| .. ..|. . | .....|. |. . |. .....|||||||. . ..|. | ... | . |. |.|||||
YWpaepkekvkledgkikvlalseekeegyiltrlrleekgeer.rlv..HfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcs
AGVGRTGTFMAIDMGLQQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLES
||||||||..|.|.... |... .|...||...|..||..||. .|| |. ||.|
aGvgRtGtlialDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyeflykavvey
|
|||||||||
subfamily_PTPN23_pd | Subfamily PTPN23 | 1029-1294 | 5e-60 | 197.7 | In-house | 13-281 (288) | alignment | ||
Range on Protein: 1029-1294
Range on HMM: 13-281/288.0
GNEGFKNQYCTLNSGD----NEHSVTIAVTPSNRplNRFGNIVVYDDNRILLNqipgntDCQNDYINACYIDGYSQ-DYKYIATQGPVTKTLVDFWRLIW
|. ...... |.. . ...|..|| . |.. ||. .|. || ||. |. . ..|||||... . | ..||||.| .|| |||....
gktaldkkfkeleqkqdkearkrsiaiaklysek..nrsrdilPyDhnRvklr......gskDDYinAsfvkdlspgcPdfiatqaPlqstlnDFWlmvy
QERPPVIVMVTNLKEDTTIKCHQYWPEH--GSTSYGPFRIELTKEQVLTDYTIRKMQLTLLGSDQPpLMITQYHFTSWPDHGVPEYATSILQFHRRIKNE
... .||||... .| |...||||. ....|.... | ... . . |...|. |..|. ... ..||||..|||. ..||| ...
eqkssviVmllskeelgkpkvdrYwPedkgetvkfgdlsvtlksvretethvervlkletldadav.ksvshlqltsWpelGvPasPetllqfldevesa
----YKPTKGPMLVHCSAGVGRTGTFMAIDMGLQQAEKEGGI-DIISIINKMRQQRMKMVQTADQYIFVNDAVLESVT
...| |..|||||||||||.| . ... ||. |. ||| .....|.|| |||. .|. |. .|||| .
yeavqrksktPlvvhCsaGvgRtgvfalvyaavrelekgnglldiiqvvsrlreqRrfmvqekeqlkfsyeavleaar
|
|||||||||
0045098 | (Phosphotyrosine protein) phosphatases II | 1334-1581 | 9.5e-60 | 197.7 | In-house | 18-273 (278) | alignment | ||
Range on Protein: 1334-1581
Range on HMM: 18-273/278.0
VTQRPDEVTHNIASQNNDKNRSTQFLPRDNYRVPlkgehpDYINAVFINGYkeKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCHEKEIDQEVCYQY
.. |.|.|... | |||| ...|| |. || ||||| .|.|| .|.||.. |. .|. .||.|. . ..|.||||....| ..| |.||
llgipseitpalylgnldknRykdilpydhsrVk......dYINAsyidgy..pkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaqy
WPStPSGLVIGEYAIMLSSEEIYNGYIERKLEVKNT----NTGSTQSVMQYQITNWVSTRKMAKP--QTILSVIEEMYKTQR------------RRGNTS
||. . |..|.. . | |||... |. |.|.| |. ... . | ......| | . .|...|.. . .. ...
wpe.ggsltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggp
IVVHCSDTVGRSAMFCAAATTINKCktEGVIDVFQVLKSQRIQKPG-SVQTVQQYQGIFQIVLTYLD
..|||| |||.....|| . . . ||..|.....| | |.|| .||. .||. ... .| .|
vlVHCsaGvgRtGtlvaaylmlell..eggvdlleavkelrsqRpglavqnleqyrflyefllelll
|
|||||||||
subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 1347-1588 | 1e-59 | 196.8 | In-house | 7-250 (250) | alignment | ||
Range on Protein: 1347-1588
Range on HMM: 7-250/250.0
SQNNDKNRSTQFLPRDNYRVPLKGEH----PDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCHEKEIDQEvCYQYWPSTPSgLV
||..||| ..... |. || |. |. |||||.|..||.|.||||.. .|. .| .||.|. ......|||| || ... . |||| .
pqnkeknryadiialdssrvvLekekgdkesdyinasflhgyderkafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqywPveka.ek
IGEYAIMLSSEEIYNGYIERKLEVKNTNTGSTQSVMQYQITNWVSTRKMAKPQTILSVIEEMYKTQRRRGNTSIVVHCSDTVGRSAMFCAAATTINKCKT
|. . | |.|.. |. ||| . ... . . | |.. ..| .. ...| ..... ..|.. ||. ..|.|| |||| |.| . ... |.
yGdvtvsllskeefadytkrklklskakkaderivrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidavlerlkk
EGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYLDSFETYSN
| |.|||.|.| |...|..|.. .|| ...|.| .|||.| |..
ekvvdvfkvikvlrkdrphavesleqyvfvyeiilkaldsvedyar
|
|||||||||
subfamily_CG7180_pd | Subfamily CG7180 | 1052-1298 | 7.3e-59 | 193.8 | In-house | 37-295 (296) | alignment | ||
Range on Protein: 1052-1298
Range on HMM: 37-295/296.0
AVTPSNRPLNRFGNIVVYDDNRILLNQIPGNTDcqNDYINACYIDGYSQDYKYIATQGPVTKTLVDFWRLIWQERPPVIVMVTNLKEDTTiKCHQYWPEH
.. || || ..| || ||..|... |. . .||||| |.|.. .. .|| |..|...|. .||||...| .|..|. . . ....|||..
glrkenreknrdvkvvPyDynRvvLekldGeek..sdYinavyvdsflkkkeyivteapkketvdefWrlvydeeisavvvLtktfdfak.mypsywpnk
GSTSYGPFRIELTKEQVLTDYTIRKMQLTLL---------GSDQPPLMITQYHFTSWPD-HGVPEYATSILQFHRRIKN-----EYKPTKGPMLVHCSAG
. . ||.. .|...|. ... .||...|| . . . .......| |. . || ....... ||.. . .|..||..|..| |
skeqygeifveiveekqyanlkirtfkltkkivalteqekqvkaetRivklfqlteWeledkvPlstnalielrrrvrlwrekvdedpeegPvvvvssdG
VGRTGTFMAIDMGLQQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLESVTCGNT
..|.| ..|||. |...|||. .|. . ..|..| ..|.. ..| .. | .|| | |. .
asRsGvylaidanlelvekeeevdvFeavktlrrsRpqLvenveeYkyiYdvlleavlcnkd
|
|||||||||
0040439 | (Phosphotyrosine protein) phosphatases II | 1341-1580 | 3.7e-58 | 192.4 | In-house | 3-246 (249) | alignment | ||
Range on Protein: 1341-1580
Range on HMM: 3-246/249.0
VTHNIASQNNDKNRSTQFLPRDNYRVPLKG----EHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCHEKEIDQEVCYQYWPS
... . | ||||.. .|| |. || |. .. ||||| .|.||. |..||.. |. .| .||.|. . ..|.||||....| ..| |.||||.
ysvallpenkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywpl
tPSGLVIGEYAIMLSSEEIYNGYIERKLEVKNTNTGSTQSVMQYQITNWVSTRKMAKPQTILSVIEEMYKTQRRR-GNTSIVVHCSDTVGRSAMFCAAAT
. |..|.. . | |.|....|. |.||..|. .|.. |...|.|.| . ....|. ||.. | ... .. ..||||. |||...|.|| .
.ggsleygdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaayl
TINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYL
.. ..|. .|.....| | |.||.||. .||. . ...| .|
mleqlekelgvdleeavkllrsqRpgavqnpeqyrflyeallell
|
|||||||||
0042113 | (Phosphotyrosine protein) phosphatases II | 1346-1580 | 3.7e-58 | 192.2 | In-house | 6-243 (245) | alignment | ||
Range on Protein: 1346-1580
Range on HMM: 6-243/245.0
ASQNNDKNRSTQFLPRDNYRVPLKGEH----PDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCHEKEIDQEVCYQYWPStPSGL
| ||||....|| |. || |. . ||||| ...||. .. ||.. |. .| .||.|. . ..|.||||. | | ... |.||||. . |
lpenkdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywpl.gesl
VIGEYAIMLSSEEIYNGYIERKLEVKNTNTGSTQSVMQYQITNWVSTRKMAKPQTILSVIEEMYKTQRRRGNTSIVVHCSDTVGRSAMFCAAATTINKCK
..|.. . | |||....|. |.|||.|. .. .. |..|. ..| ....|...|.. | ... .|. ..||||. |||...|.|| . .. .
tygdftvtllseehlddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleqle
TEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYL
.|. .......| | |.||.||| .||. . ...| .|
kelgvsleeavkelrsqRpgavqtpsqyrflyeallell
|
|||||||||
subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 1319-1585 | 2.5e-56 | 186.0 | In-house | 20-288 (319) | alignment | ||
Range on Protein: 1319-1585
Range on HMM: 20-288/319.0
TGRTGFIDQFTVLEQVTQRpdEVTHNIASQNNDKNRSTQFLPRDNYRVPLKG----EHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVT
|| |.. .| |.. .. .... .|..||| .. |. |. || |. | ||||| ||.||.|...|| . .|. || .||.|. ....
tgetllekefkllkeavnd..tfdsaskeenkkknryqnilaydrtrvvlseldgvegsdyinasfidgyqerekfiatqaPlentiedfWrmvWeeess
AIVMLCHEKEIDQEVCYQYWPSTPSgLVIGEYAIMLSSEEIYNGYIERKLEVKNTNTGS-TQSVMQYQITNWVSTRKMAKPQTILSVIEEMYKTQRRRGN
.|||.. .| . . .|||.. . |.. . | .|| ..|| |||.... .. | .|...| |.| | ...| ..... |.... .
ivvmltklveklkvklkkywpeenf.eeyGrlivtleeeeeledyiirklklnkkssevetRevkhfqyteWpdhdvPekatslldllkrirksrektqs
TSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYLDSFET
||||||. ||| |.. .... | |||.|||.. . |.|.. ||. .||. |....| ......|
gPivvhCsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyealleaveagdt
|
|||||||||
subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 1012-1300 | 7.7e-56 | 184.2 | In-house | 3-243 (392) | alignment | ||
Range on Protein: 1012-1300
Range on HMM: 3-243/392.0
LIPVGQFGEFVANGHAkgNEGFKNQYCTLNSGDNeHSVTIAVTPSNRPLNRFGNIVVYDDNRILLNQIPGNtdCQNDYINACYIDGYSQDYKYIATQGPV
||| || || . . . | ... | . | . |.| .. | . ||..||. || .|. |. | ..||.|| ||... .. |||.|||
pipvaqfpafveknrh..salffeefhdlpgpdi.ypqtvaqkeinlkknryknilpydsarvkleviddi..pdsdylnasyipsfdnekayiasqgpn
TKTLVDFWRLIWQERPPVIVMVTNLKEDTtikchqywpehgstsygpfrieltkeqvltdytirkmqltllgSDQPPLMITQYHFTSWPDHGVPEYATSI
. .| ||||...||.. |.|||.||| . ..|.||| |||..||....|.
aaslddfwrmvfqenvttiamvtklkegd...........................................kgddartvaqfhftewPdkdvpkhtssl
LQFHRRIKNEYKPTKGPMLVHCSAGVGRTGTFMAIDMGLQQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLESVTCGNTQV
|.| . .| .. |...|||||||||| ..|| . .|.| .|.. .. ..|..| |||| .|| |. |||| . || .
lkfikevkadfGqythpliihcsagvgrtgvvisidsvvahakktrmvdvfnfvtnirrkrpymvqtkeqyafiygavledllwrntli
|
|||||||||
subfamily_PTPN14_pd | Subfamily PTPN14 | 1046-1293 | 1.1e-55 | 183.7 | In-house | 38-296 (300) | alignment | ||
Range on Protein: 1046-1293
Range on HMM: 38-296/300.0
EHSVTIAVTPSNRPLNRFGNIVVYDDNRILLNQipgNTDCQNDYINACYIDG--YSQDYKYIATQGPVTKTLVDFWRLIWQERPPVIVMVTNLKEDTTIK
. .. | | | . ||| ... |.|||. |. . . ...|||| | .....||..|||. .|. |||...|.. .|||.|. .|| |
dallstaklpenaeknrfkdvlPyednrvelsp...tkenstgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivmlteeeedgkek
CHQYWPEH----GSTSYGPFRIELTKEQVLTDYTIRKMQLTLLGSDQP-PLMITQYhfTSWPDHGVPEYATSILQFHRRIK------NEY---KPTKGPM
...|.|.. . .| |.. . . .. ....| | | . ... || | |||||||| .. |.. .... |. | .| |.
sfkyfPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqy..tDWpdhgvPeDvkgflsyLeevqsvrrktnseveskeskPPv
LVHCSAGVGRTGTFMAIDMGLQQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLESV
|||||||||||| . |. .. |.. ||| ......|.||| .||| || || .......
lvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLreqrmllvqtlaqYkfvYkvlikyl
|
|||||||||
subfamily_PTPRA_pd | Subfamily PTPRA | 1345-1579 | 1.3e-54 | 180.3 | In-house | 52-294 (330) | alignment | ||
Range on Protein: 1345-1579
Range on HMM: 52-294/330.0
IA--SQNNDKNRSTQFLPRDNYRVPLK---G-EHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCHEKEIDQEVCYQYWPSTP
.| .|..||| . || | || | | |. ||||| ||.|||||. || | | .| .||.|| ... ..|||| . || ..| |.||||.
laskeenkeknrvvnilPydfsrvilsvkeGveesdyinasfidGykekdkfiaaqGPkeetvedfwrmiweqksativmltelkerkeekcaqywPdeG
SgLVIGEYAIMLSSEEIYNGYIERKLEVK----NTNTGSTQSVMQYQITNWVSTRKMAKPQTILSVIEEMYKTQRRRGNtSIVVHCSDTVGRSAMFCAAA
. . |. . . |.. . | ||. |. .|. ... | |. | | ..|. .|...... |.... .. .|||||| |||. |..
l.vtyGnirvevedetvlvdytvrkflvqqlpdatrekksrlvrqfhftswPdvGvPfepiGmlkllkkvkklnqqsag.pivvhcsaGvGrtGtfivld
TTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTY
. ... |.|...|||...|. | |.| ||| .||. |....| |
avlervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvlley
|
|||||||||
0051429 | (Phosphotyrosine protein) phosphatases II | 1087-1292 | 1.6e-53 | 177.4 | In-house | 4-224 (272) | alignment | ||
Range on Protein: 1087-1292
Range on HMM: 4-224/272.0
NDYINACYIDGYSQ---DYKYIATQGPVTKTLVDFWRLiWQERPPVIVMVTNLKEDTTIKCHQYWP------------EHGSTSYGPFRIELTKEQVLTD
..|||| ...|| . . ......|| . | ||||| .... .||..... | ||..||| .. . .|| .|. |..|..|.|
sgyiNardvggygrvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseellld
YTIRKMQLTLLGSDQPPLMITQYHFTSWPDHGVPEYAtsILQFHRRIKNeykptKGPMLVHCSAGVGRTGTFMAIDMGLQQAEKEGGID--------IIS
|..|...|||| | . .......|.|.|||||||. | .|.. . . . .||.|||||||..||||. |... |.. ..| .| .
yilrellltlllsagearevmhlhytdwpdhgvpqea..llellellld.....ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlylee
IINKMRQQRMKMVQTADQYIFVNDAVLES
.....|.||...||| .||.|. .|.||
aveelraqrpgavqteeqylflyeallel
|
|||||||||
subfamily_Ptp69D_pd | Subfamily Ptp69D | 1320-1583 | 3.6e-53 | 175.7 | In-house | 20-289 (307) | alignment | ||
Range on Protein: 1320-1583
Range on HMM: 20-289/307.0
GRTGFIDQFTVLEQVtQRPDEVTHNIASQNNDKNRSTQFLPRDNYRVPLK----GEHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTA
|.. . ||. . . . . |. |||. . . |..|| || |. ||||| ||.|||||| ||.| |. .|. .||.|| . .||
tdfglakeyekLear.eidkstkvsekkenalknRyedikafDktRvkLkkingkedsdYinasfikgykekkkfiaaqdPveatigDfWRmiaeqevtl
IVMLCHEKEIDQEVCYQYWPSTpSGLVIGEYAIMLSSEEIYNGYIERKLEVKNTN-----TGSTQSVMQYQITNWVSTRKMAKPQTILSVIEEMYKTQRR
|||| ..| ... | .||| |. . | ||| . ||.|.|.| ... .. |.||. |.| . ....| .||.... ..
ivmlsnlteknrkkcakYWpie.devqygdilvklvseekhsdyiiReldvskkkeesgevedsrkvvqyhytgWkDskvPevargllklieqvrelykl
RgNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYLDSF
.. |||||| ||||..| | . ....|.| .|.|.. | | |.. || .||. ... .| | .
n.rsPivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnllvqsleqYvflyralldyssyg
|
|||||||||
subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 1317-1584 | 3.3e-52 | 172.3 | In-house | 16-285 (288) | alignment | ||
Range on Protein: 1317-1584
Range on HMM: 16-285/288.0
TKTGRTGFIDQFTVLEQVtQRPDEVTHNIASQNNDKNRSTQFLPRDNYRVPLKG----EHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRN
...|||| ... .| .. .. ..|| ..|..||| . || | || ||. . ||||| .|.|.|.||..| . .|. .| .||... ...
sarnrtgfseeynsLaal.ektksvtagrlavnakknRyrnilpyDekrvklkkleeeagaDYinasyidgekkkkkyiatqgPladtvndfWelvyenk
VTAIVMLCHEKEIDQEVCYQYWPSTPSGLVIGEYAIMLSSEEIYNGYIERKLEVKntNTGSTQSVMQYQITNWVSTRKMAKPQTILSVIEEMYKTQRRRg
.. |||| . | ... | .|||.. |. ..| ... . ...|||... ... . ||| . |. . . . .| ... . ..
tstivmltelveggktkCeeYWPdadkpknyGsvtvtlveskeledfvlrkllle..kkkteleitqyqylaWpdhgvPeskapllellrqvkvanqad.
NTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYL--DSFE
|.||||. |||. | |. . |.. ..| .|||. ... | |.. |||..||. |....|. |. .
tgpiivhCsaGvGrtgtFialdalidaveeedyiDvagtvaklRkqRallvqtlkqYefiyevllslieedgva
|
|||||||||
0037934 | (Phosphotyrosine protein) phosphatases II | 1346-1579 | 1.7e-51 | 170.5 | In-house | 7-241 (243) | alignment | ||
Range on Protein: 1346-1579
Range on HMM: 7-241/243.0
ASQNNDKNRSTQFLPRDNYRVPLKGehPDYINAVFINGYKeKkaFIIAESPMFNTARN----FWKMIDDRNVTAIVMLCHEKEIDQEVCYQYWPstPSGl
.| .||| . .|| |. || |.| ||||| .|.... . .|. |. .| . ||.|. . ..|.||||....| ..| |.|||| .
lpenlsknrysdilpydhsrvkleg..sdyinanliyvtp.r..liatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywp..gev.
VIGEYAIMLSSEEIYNGYIERKLEVKNTN-TGSTQSVMQYQITNWVSTRKMAKPQTILSVIEEMYKTQRR-------RGNTSIVVHCSDTVGRSAMFCAA
..|.. . | ||| ...|. |.|...|.. .. |. |..|. ..| |. .|. ..|... ... .. ..|||| |||.....||
tygdftvtllseehlddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtliaa
ATTINKCkteGvIDVFQVLKSQRIQKPG-SVQTVQQYQGIFQIVLTY
. . .. | .|.....| | |.|| .||| .||. . ...| .
ylmllll...g.vdleeavkllreqRpgkavqtpsqyrflyeallel
|
|||||||||
subfamily_PTPRG_pd | Subfamily PTPRG | 1320-1585 | 4e-51 | 168.9 | In-house | 17-292 (563) | alignment | ||
Range on Protein: 1320-1585
Range on HMM: 17-292/563.0
GRTGFIDQFT-VLEQVTQRPDEVTHNIASQNNDKNRSTQFLPRDNYRVPLK---GEH--PDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNV
| .|| .| . ...... ...| . .| ||| .. .. |. || |. |.. ||||| .|.||. .||||.. |. .|. ||.|| ..||
gdigfseefealqsetiskdldaehsqkpenkrKnRylnivaydrsRvklsplpgkkkklDYinAnyidGyqkskafiatqgplkdtfddFWrmiWeqnv
TAIVMLCHEKEIDQEVCYQYWPStPSGLVIGEYAIMLSSEEIYNGYIERKLEVKNTNTGSTQ------SVMQYQITNWVSTRKMAKPQTILSVIEEMyKT
. |||. .| .. | .|||. . .|. . | .||. | .|.| .||.. .. |.||. |.| . .. |. .. ..
aiivmitnlvergrrkcdvYWPk.desetygalqvtlieeevlalytvrtlviknlklkkkkqcdteklvrqyhytkWPdhgvPehslpvLifvkks.sa
QRRRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYLDSFET
... |||||| |||. .... | ... ..| ...||..|| | |.. ||| ||. .....| . | ||
ankaeaGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvqteEqYiflhdalleaiasket
|
|||||||||
subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 1316-1582 | 2.2e-50 | 166.3 | In-house | 9-278 (281) | alignment | ||
Range on Protein: 1316-1582
Range on HMM: 9-278/281.0
DTKTGRTGFIDQFTVLEQVTQRpDEVTHNIASQNNDKNRSTQFLPRDNYRVPL----KGEHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDR
.. .||| ... |... .. . | | .| ||| . |. || . . .. ||||| |..|||..|..|....|. .. .||.|. ..
lsqndnaGfieeyeklaaigvd.ntataskadenvlknrYsnivaYDatrvkvtpneenkntDYinanfvpgykgekeyiatqgPvPaslvafWqmvweq
NVTAIVMLCHEKEIDQEVCYQYWPSTPSGLVIGEYAIMLSSEEIYNGYIERKLEVkNTNTGSTQSVMQYQITNWVSTRKMAKPQTILSVIEEMYKTQRRR
.|.||||. .| | .. |..||| | | .|.. . .|| . |||||... ....| |..| | . |.| . |... .|. .|..|.....
kvsaivmvtreieagklkChrYWPddnselkygdvtvkstaeeekatyierkfkl.eresgetreveqlaytaWPdhGvPattkellefrkevlkltekk
GNTSIVVHCSDTVGRSAMFCAAATTINKCKTE-GVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYLDS
....|.||| |||. . | . ......| .|| .|... | .. |||| ||. ....|| .||
tkaplvihCsaGvGrtGtyialDrlvkaveaeleeldvkavvaelrkernlmvqtvvqyefvykavldaldk
|
|||||||||
0041856 | (Phosphotyrosine protein) phosphatases II | 1057-1299 | 2.3e-50 | 166.1 | In-house | 1-177 (182) | alignment | ||
Range on Protein: 1057-1299
Range on HMM: 1-177/182.0
NRPLNRFGNIVVYDDNRillnqipgntdcQNDYINACYIDGYSQDYKYIATQGPVTKTLVDFWRLIWQERPPVIVMVTnlkedttikCHQYWPehgstsy
|...||. .|. || .| .||||| ...|. . ..|||||| .|. ||.|...... .||..| ...|||
nldknrysdilpydhsr............dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt.........eelywp.......
gpfrieltkeqvltdytirkmqltllgsDQPPLMITQYHFTSWPDHGVPEyATSILQFHRRIKNeykpTKGPMLVHCSAGVGRTGTFMAIDMGLQQaeke
. . ...||....|||||||. ..|.| ..... .|| |||||||||||||. |... ...
............................ellerlgiqylylpwpDhgvpd.ldelldfieevle....eggpvlVHCsaGvgRtgtlvaaylmkkl....
gGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLESVTCGNTQ
|... .... .|..|..||.| .||.|. .|.|| . ...|.
.gvsleeavklvrsrRpgmvitpnqyfflqlallellllkktr
|
|||||||||
subfamily_PTPRB_pd | Subfamily PTPRB | 1318-1582 | 1.2e-49 | 163.9 | In-house | 21-287 (293) | alignment | ||
Range on Protein: 1318-1582
Range on HMM: 21-287/293.0
KTGRTGFIDQFTVLEQVTQRpDEVTHNIASQNNDKNRSTQFLPRDNYRVPL----KGEHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNV
. ..| ... |..| . .|. . ...|..||| |. || |. || | . .. ||||| .|.||. .. || . |. .| .||.|. ....
adsdlrfseeyeelkavgkd.qavkaaelavnraknrytnilpydhsrvkLaalkdesgsDYinanyipgynsprefiatqGPlpetvddfWrmvwekks
TAIVMLCHEKEIDQEVCYQYWPSTPSGLVIGEYAIMLSSEEIYNGYIERKLEVKNtnTGSTQSVMQYQITNWVSTRKMAKPQTILSVIEEMYKTQ-RRRG
..|||| . | .. | .|||.. . . |. . | .|| .. .. |.|.... . ....|.||. | |. |..|.|. .... ... .
siivmltqlvekgkvkCeeYWPadeepvlyGdikvtlvaeeeledwvirelkiek..ekeerkvrqyhftsWpdhgvPektktlldfvrtvreaiektas
NTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYLDS
.. |||||| |||. | | . ... ..| ..|.| .. . | .. |||..|| | | ||..| .
krPivvhCsaGvGRtGtfialdrllqaieeedyvdifgivaelReeRnllvqtekqYifihqcvldllrk
|
|||||||||
subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 1060-1290 | 1.8e-49 | 163.1 | In-house | 41-274 (287) | alignment | ||
Range on Protein: 1060-1290
Range on HMM: 41-274/287.0
LNRFGNIVVYDDNRILLNQIPgntDCQNDYINACYIDGYSQDYKYIATQGPVTKTLVDFWRLIWQERPPVIVMVTNLKEDTTIKCHQYWPEH-GSTSYGP
||..... .||.|.|| . . . ||||| |. .| .| ..||.|||.. |. ||||.....| .....| |.. ||..||||. |
knryadvlPiddtrvllsaeg...elGsdyinanyvasytddeafiaaqgPiaatvrdfwravletrsasvitmtreveearlkcykywPerevPmrvGG
FRIELT-KEQVLTDYTIRKMQLTLLGSDQPpLMITQYHFTSWPDHGVPEYATSILQFHRRIKNEY-----KPTKGPMLVHCSAGVGRTGTFMAIDMGLQQ
. . | ... .|..| ..| | . . .. |... ||||.... | ....| .|. ||..||...|.||.|...|. . ...
ysvvlldydikePeygvralrlidletrea.rvvkqldllswPdkvlaPtavglirfvldvkqhielardasevGPlvvhddvGiGrsGillatlvlvsr
AEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVL
|. | .|. .. ..|..| .||.. |. .. .|.
ledlGrvdvaavvirlreyraalvqavvqlrllyealv
|
|||||||||
subfamily_PTPN23_pd | Subfamily PTPN23 | 1319-1580 | 1e-48 | 160.6 | In-house | 12-280 (288) | alignment | ||
Range on Protein: 1319-1580
Range on HMM: 12-280/288.0
TGRTGFIDQFTVLEQVTQRP-DEVTHNIASQNNDKNRSTQFLPRDNYRVPLKGEHPDYINAVFINGYKEK-KAFIIAESPMFNTARNFWKMIDDRNVTAI
|.|.. .| ||| .. . . || . .||||. || |. || |.|.. ||||| |... ||.. .|. .|. ||.|. .. . |
dgktaldkkfkeleqkqdkearkrsiaiaklyseknrsrdilPyDhnRvklrgskDDYinAsfvkdlspgcPdfiatqaPlqstlnDFWlmvyeqkssvi
VMLCHEKEIDQEVCYQYWPSTP-SGLVIGEYAIMLSSEEIYNGYIERKLEVKNTNTGSTQSVMQYQITNWVSTRKMAKPQTILSVIEE---MYKTQRRRG
||| ...| ... . .|||. . |.. . |.|.. . ..||.|... .. ..||. |.|.| . | |.|.| ...| .|....|.
VmllskeelgkpkvdrYwPedkgetvkfgdlsvtlksvretethvervlkletldadavksvshlqltsWpelGvPasPetllqfldevesayeavqrks
NTSIVVHCSDTVGRSAMFCAAATTINKCK-TEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYL
.| .||||| |||. .|. . ... . .|..|. ||.. | |. .||...|.. ...||..
ktPlvvhCsaGvgRtgvfalvyaavrelekgnglldiiqvvsrlreqRrfmvqekeqlkfsyeavleaa
|
|||||||||
subfamily_PTPN12_pd | Subfamily PTPN12 | 1318-1580 | 2.2e-48 | 159.6 | In-house | 4-277 (290) | alignment | ||
Range on Protein: 1318-1580
Range on HMM: 4-277/290.0
KTGRTGFIDQFTVLEQVTQRP--DE---VTHNIASQNNDKNRSTQFLPRDNYRVPLKG----EHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMI
|.|. | .|. | ..... .. .. ...| ||| || |. || |. |. ||||| ||.| ..|...| | .|. .| .||.||
kegeeefakefqklkklsekykaekvysteagekeenvkknrykDilPydksrvelskieeeegsdYinanfikgvegkleyiaaqgPLpktlddfWrmi
DDRNVTAIVMLCHEKEIDQEVCYQYWPSTPSGLV-IGEYAIMLSSEEIYN-GYIERKLEVKNTntGSTQSVMQYQITNWVSTRKMAKPQTILSVIEEMYK
.. ||. .||.|.| |... | .|||.. . .||. . |..|. . ... | |.|.. . ...| |.. |.| ......|..||.. .
weknveivvmaCrevelgkkkCerYWpeegeeelefgefevtleeekavdddflirtLkveaq..kesrkvyqfhYtaWPDhgvPssaksllelielvre
TQRrRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGV---IDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYL
.|. . .. .||||| ||| .| . . |.| . .|||... . | |.. ||| .||. ... |. ..
lqe.sedaPlvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelv
|
|||||||||
subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 1347-1585 | 6.3e-48 | 158.4 | In-house | 49-289 (297) | alignment | ||
Range on Protein: 1347-1585
Range on HMM: 49-289/297.0
SQNNDKNRSTQFLPRDNYRVPLKG--EH--PDYINAVFINGYKEkkAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCHEKEIDQeVCYQYWPSTPSGLv
| .|.| . || | || |. .. ||.|| |..|.|. .| . || .| .||.|. | .|..|||| ...| |. | .||. . .
kvnfeksRYkniLPydssRvkLaivnddpdsDyvnasfvkgnkh..rlittqmPmkatvadfWamvldeqvstivmlnddnerdk.kcaryWsdkgvtt.
IGEYAIMLSSEEIYNGYIERKLEVKNTNTGSTQSVMQYQITNWVSTRKMA--KPQTILSVIEEMYKTQRRRGNTSIVVHCSDTVGRSAMFCAAATTINKC
|. ...|.| . .|.|.|.|||.. .. ... | ||| ..| . . ...| .|.|. |. . .. ..|||. ||| ..... . .
fGdvsvvllsvsereGfikrelevtkgkakarrvvkqyqfveWPdkaverkdsassllklisevrkdfsqnaegPllvhclaGvGrtgvlltidsvvaea
KTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYLDSFET
| | .|.|...| | ..| ||| .||. ....|| .| | .|
krekevdifglvkklrqerpylvqtkeqykfvyvavleallsedt
|
|||||||||
subfamily_PTPRK_pd | Subfamily PTPRK | 1347-1578 | 8.1e-48 | 157.8 | In-house | 41-275 (314) | alignment | ||
Range on Protein: 1347-1578
Range on HMM: 41-275/314.0
SQNNDKNRSTQFLPRDNYRVPL---KGE-HPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCHEKEIDQEVCYQYWPSTPSGlv
.|..||||.. |. |. || | .|. . ||||| .|..|| .|||.. |. .| ..||... | | ..|||| . .| . |..||| .
denreknrsgdilaydrsrvflitidgdpssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasivmltelvevgrvkClkyWPedtev..
IGEYAIMLSSEEIYNGYIERKLEVKN--TNTGSTQSVMQYQITNWVSTRKMAKPQTILSVIEEMYKTQRRrGNTSIVVHCSDTVGRSAMFCAAATTINKC
|. ..| . |. . .. | . |.. . .. | |.| ..| . . ...|... .. |.| .. |||||| ||. .|.| .. ..
ygdikvelvetellaelvvrifrveklargqeeirevrqfqflgWpdhdvPvsatgllklvrrvkksqee.eaGrivvhCsaGaGrtGtfiaidivldmi
KTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLT
..|||.|||.. |. | .|. |.| .||. |....|
eregvvdvfnavktlrsrkvnmveteeqykfiydvile
|
|||||||||
0036282 | (Phosphotyrosine protein) phosphatases II | 1087-1287 | 1.9e-47 | 156.5 | In-house | 2-164 (174) | alignment | ||
Range on Protein: 1087-1287
Range on HMM: 2-164/174.0
NDYINACYIDGYSQDYKYIATQGPVTktlvdFWRLIWQERPPVIVMVTNLKEDTTIKCHQYWPEhgstsygpfrieltkeqvltdytirkmqltllGSDQ
.||||| ..|.. ..||.||| . ||....... ..||....||. ||..|||| ..
sdyinaspldlsyitprliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe................................lred
PPLMITQYHFTSWPDHGVPEYATsILQFHRRIKNEYKP-TKGPMLVHCSAGVGRTGTFMAIDMGLQQAEkEGGIDIISIINKMRQQRMKMVQTADQYIFV
. .. ||... |||||||. .. .|.| ..... .. .||.|||||||||||||..|... |.. . |. .|..... ..|.||..|||| .||.|.
lerlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtpsQyrfl
ND
.
yy
|
|||||||||
subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 1321-1578 | 1.2e-46 | 154.2 | In-house | 23-277 (315) | alignment | ||
Range on Protein: 1321-1578
Range on HMM: 23-277/315.0
RTGFIDQFTVLEQVTQRPDEVTHNIasQNNDKNRSTQFLPRDNYRVPL----KGEHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAI
. || ... . .| .|...| .| .||| . .. |. || | . .| ||.|| ||.||. |. .| |..| .. ..||... . ... |
kngfkqdyesipggqlhpldvakki..enkqknryiniiaydksrvqlpllendphsdyvnanfidGynkkrryiaaqgpnvasvkdfwrlvfeedigki
VMLCHEKEIDQEVCYQYWPSTpsGLVIGEYAIMLSSEEIYNGYIERKLEVknTNTGSTQSVMQYQITNWVsTRKMAKPQTILSVIEEMYKTQRRRGNTSI
||| | ... . .||| .. |.... . |||... | | | | . . |.|...| | . ...| . | . | . ..|
vmltnlvegekrkaekywpdk..kviyGkitvtrkseevnteytvrtlsv..vfgdnirevvqlhytswp.dmgvpkytiplmnlirtvkqhhtnsvgai
VVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLT
|||||. |||. |.. . ... ..| .|||..... | .. . ||...||| |....|
vvhcsaGvGrtGtfitldavldqaeaenaidvynfitgvrqnrikmvqvaeqyqfiydalle
|
|||||||||
subfamily_PTPN6_pd | Subfamily PTPN6 | 1310-1582 | 6.7e-46 | 151.7 | In-house | 14-299 (306) | alignment | ||
Range on Protein: 1310-1582
Range on HMM: 14-299/306.0
NRMSKPDTKTGRTGFIDQFTVLEQVT-QRPDEVTHNIASQNNDKNRSTQFLPRDNYRVPLK---GEHPDYINAVFINGY--KEKKAFIIAESPMFNTARN
....| .......|| ..| |.| .. . .. .|. ||| || |. || || ||||| .|.. ...|..| .. . .| .
selekeeeslekagfeeefeelqqeeakkllsrkegakpenkeknryknilPfDhtrvilkepsvpgsdyinanyikkevkgsdksyiatqgclettvsd
FWKMIDDRNVTAIVMLCHEKEIDQEVCYQYWPSTPSGLVIGEYAIMLSSEEIYNGYIERKLEVK-NTNTGSTQSVMQYQITNWVSTRKMAKPQTILSVIE
||.|. . | . |||. .| | .| |..|||.. . |.. .. ||. . || |.| |. ... .....|.||. ..| ..|...|. .|
FWrmvwqensrvivmttkevErgkekCarYWPdeeekeeyGkisvtnvseksladYilRelsvskkkkkkeerevfqyhfksWPdhgvpkdpgavLdfle
EMYKTQRRRG---NTSIVVHCSDTVGRSAMFCAAATTINKCKTEGV---IDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYLDS
.. . |.. . .||||||. .|| | . ... ...|. ||. .. || | |. | ||| |||. ..... .|...
dvnrkqeeleeaeagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqteqqykfvykaikkyiet
|
|||||||||
subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 1317-1581 | 7.8e-46 | 151.2 | In-house | 12-277 (515) | alignment | ||
Range on Protein: 1317-1581
Range on HMM: 12-277/515.0
TKTGRT-GFIDQFTVLEQVTQRPDEVTHNiaSQNNDKNRSTQFLPRDNYRVPL----KGEHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDR
.| ..| | ..| | |. |. . | ||| || |. || | | ||.|| .|.... ||.| . | . .||... .
nknrhttlfseefhdlpgpniypqtvaqe..einfkknryknilPydsvrvklevindnPhsdyfnasyipsfdndkayiasqgPnkasvddfWrlvlqe
NVTAIVMLCHEKEIDQEVCYQYWPSTPSGLV-IGEYAIMLSSEEIYNGYIERKLEVKNTNTgsTQSVMQYQITNWVSTRKMAKPQTILSVIEEMyKTQRR
|||.|.|. . || |. | .||| |. | |.. . | | | | | |||.| . .. | |.. |.| . ...| .| |. |...
nvttiamvtklkegdkikcgkyWPdkpgdsvkfGsikvelvsleactggikrkltvlkgdd..srtvtqfhfteWPdkGvpkhtssllklikev.kadhg
RGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYLD
. . ....||| ||| ..... . . || ..|||.... | ..| ||| .|| |...|| .|
qythpliihcsaGvGrtGvvisidsvvahakttrmvdvfnfvtnirqkrpylvqtqeqyafiygavledll
|
|||||||||
subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 1321-1582 | 9.5e-46 | 151.4 | In-house | 22-290 (325) | alignment | ||
Range on Protein: 1321-1582
Range on HMM: 22-290/325.0
RTGFIDQFTVLEQVTQRPDevTHNIASQNNDKNRSTQFLPRDNYRVPLKG----EHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNvTAI
. || .| .| . . .| .||| .. |. || |. . ||||| ... .|.|. |. | .|. .| ..|... | . ...
qdgfahefgllpsddgiak..kvamkpenkaknrfknvvaldksrvvletkkddpssdyinasylrddkkkdvflaaqaPltatindlWrlvldWr.csv
VMLCHEKEIDQEVCYQYWPST-PSGLVIGEYAIMLSSEEIYNGYIERKLEVKNTNTGSTQSVMQYQITNWVSTRKMAKPQTILSVIEEMYK---TQR--R
|.. | . ... | .||| | . | . | . |. |.|.||... | |.|| |.|. | .| |..|... . . . .
vvvlneldlgkdrcavywpkemgksktfGglevklrtieeisdyvhrvldvkqvkkGetrsvkqfqlqswddmGvqkrpatlisilqlvkavservtant
RGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYLDS
.. | |.||||. |||. .| . . ..| .| .|.|...| | ..| |.|| || |.. . .. |
kastpilvhcsaGvGrtGvfislysalakvieesrvdifgfvkklrkdrpsmvetvdqyiliyealveayms
|
|||||||||
subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 1345-1581 | 4.5e-45 | 148.8 | In-house | 40-278 (315) | alignment | ||
Range on Protein: 1345-1581
Range on HMM: 40-278/315.0
IASQNNDKNRSTQFLPRDNYRVPL----KGEHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCHEKEIDQEVCYQYWPSTPS-
..| ||| || |. || | . . ||||| .|..... ||.| . | . .||.|. . .||.|||. . .| |. | |||| .
retinfkknryknilPldsarvkleviddsPdsdyinasyiksvdddkayiasqgPlkasvddfwrmvlqekvttivmvtkkqegdkikcrqywPdrkad
GLVIGEYAIMLSSEEIYNGYIERKLEVKNTNTgsTQSVMQYQITNWVSTRKMAKPQTILSVIEEMyKTQRRRGNTSIVVHCSDTVGRSAMFCAAATTINK
|.. . | | | . . ||| ...... .. | |.| |.| . ..| .| |. |..... . |..|||| |||. ..... ...
svefGsikvellsleadtdgvarklvtrksee..srtvtqfqftewPdkGvdkqtssllklikev.kadngkkefsllvhcsaGvGrtGvvisidevvaq
CKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYLD
| . ..|||...| | ..| ||| ..| |...|| .|
ikrtrsvdvfnfvknlrakrpylvqteeeyafiydavledll
|
|||||||||
subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 1320-1577 | 3.1e-44 | 146.6 | In-house | 32-288 (319) | alignment | ||
Range on Protein: 1320-1577
Range on HMM: 32-288/319.0
GRTGFIDQFTVLEQVTQRPDEVTHNIASQNNDKNRSTQFLPRDNYRVPLK---G-EHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTA
.| . .| . ... . |. || |||| .. |. |. .| |. | | ||||| |..||. |. .| | |. || .||.|| . |...
dltklevefrracklgvnladqtfanldqnkdknriinilafdknvvklerliGeefsdyinasfvtGyqrkdkyiaaqGPldntladfWrmiweyncst
IVMLChekeidQEVCYQYWPSTPSgLVIGEYAIMLSSEEIYNGYIERKLEVKN-TNTGSTQSVMQYQITNWVSTRKMAKPQTILSVIEE-MYKTQRRRGN
||.| .. | |||| ... . ..| | . |. |..|. . .. ... |. . | . | .. ... . |.. ...
ivllt......kdkcsqywplkiv.ikeerfkvkvdsveetaeyvvrdielsedgkekdirkitqfhflGwpdvGvpdypsdlmrlvkkvrhltskenhr
TSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVL
..|||||| |||. .. . . ... | | .||..... | |.. || . ||. |. .|
anivvhcsaGvGrtGvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysall
|
|||||||||
subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 1340-1577 | 4.4e-44 | 146.1 | In-house | 16-252 (284) | alignment | ||
Range on Protein: 1340-1577
Range on HMM: 16-252/284.0
EVTHNIASQNNDKNRSTQFLPRDNYRVPLK---G-EHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLChekeidQEVCYQYWP
. |. || |||| .. |. |. .| |. | | ||||| ||.||. |. .| . |. || .||.|| . |...||.| .. | ||||
dqtfanldqnkdknrighilafdknvvklerliGeefsdyinasfitGyqrkdkyiatqGPldntladfWrmiweyncstivllt......kdkcsqywp
STPSgLVIGEYAIMLSSEEIYNGYIERKLEVKN-TNTGSTQSVMQYQITNWVSTRKMAKPQTILSVIEE-MYKTQRRRGNTSIVVHCSDTVGRSAMFCAA
... . ..| | . |. |..|. . .. ... |. . | . | .. ... . |.. .....|||||| |||. .. .
lkiv.ikeerfkvkvdsveeseeyvvrdielsedgkekdirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrtgvyivl
ATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVL
. ... | | .||..... | |.. || . ||. |. .|
dvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysall
|
|||||||||
subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 1347-1581 | 5.3e-44 | 145.4 | In-house | 26-269 (274) | alignment | ||
Range on Protein: 1347-1581
Range on HMM: 26-269/274.0
SQNNDKNRSTQFLPRDNYRVPLKGE-----HPDYINAVFINGYKE-KKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCHEKEIDQEVCYQYWPSTPSG
. .. ||| .. || .| || |. | .|||| .| ||.| .||.. . |. || .||.|| ..|. |||| . || ... | .|.| . .
fgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneqkCavyfPdaedy
LVIGEYA---IMLSSEEIYNGYIERKLEVKNTNTgsTQSVMQYQITNWVSTRKMAKPQTILSVIEEMYKTQRRRGNT--SIVVHCSDTVGRSAMFCAAAT
. ..| | .. |.| ||| .|... ..||. | |.| .. ...|.|....|. ...... . ..||||| .|| .| |.
eiserygdveikvekiverndysvrklvlkyler..ersvkhywytdWPdhksPddantlldlvleveesreeenaklapvvvhCsaGiGrtGcfiaisi
TINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYLD
.... . |.|.||... |... | ||| .||. |.... ||
avrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralclylk
|
|||||||||
0046846 | (Phosphotyrosine protein) phosphatases II | 1085-1290 | 1.8e-43 | 143.6 | In-house | 10-170 (176) | alignment | ||
Range on Protein: 1085-1290
Range on HMM: 10-170/176.0
CQNDYINACYIDGYsqdyKYIATQGPVTKTLVDFWRLIWQERPPVIVMVTNLKEDTTIKCHQYWPEHGSTSYgpfrieltkeqvltdytirkmqltllgs
||||| .|.|. ..||||||. .|| ||........ ..|..|...| .||..|||| . ..
ldldyinanlilgs....rpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgi............................
dqpplmitQYHFTSWPDHGVPEYaTSILQFHRRIKNEYKPTkGPMLVHCSAGVGRTGTFMAIDmglqQAEKEGGIDIISIINKMRQQRM-KMVQTADQYI
||... |||||||.. . .|.. . |.. .| || |||||||.|||||. |.. |.| |... .. ..|.||. ..||| .||
........qylhlpwpDhgvpdl.elllellefirealkeg.gpvlVHCsaGigRtgtlvaay....llelekglsveealalvreqRplgavqtpeQyr
FVNDAVL
|. ...|
flyefel
|
|||||||||
subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 1324-1578 | 6.3e-43 | 141.7 | In-house | 8-257 (267) | alignment | ||
Range on Protein: 1324-1578
Range on HMM: 8-257/267.0
FIDQFTVLEQVTQRPDEVTHNIASQNNDKNRSTQFLPRDNYRVPLKGEHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCHEk
. .| ...... .. ||..|...|| . || |. ||.|. . .|||| ...||| |.|||. . |. || .|...| |..|. ||.| .
iekefelikkisdtsstisqsiaeknqernrlddnlpyddtrvilrtkeeeyinasyvegyktknafivtqdplkntitdfltvihdqkvpvivlltkv.
EIdQEVCyQYWPS-TPSGLVIGEYAIMLSSEEIYNGYIERKLEVKNTNTgSTQSVMQYQITNWVSTrKMAKPQtILSVIEEMYKTQRRRGNTSIVVHCSD
. ... ..|| . .. | |. | | ||.| | |.. | | .| || . .. . | | || .||.|||
ft.dnir.lfwPPkmgqakkyqdltvehslekeendyqiitlelkfkne.sahnvtlyyykkwnin.tnnkpy.lkplfgilaknqlengnrPlvvacsd
TVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLT
|||| | . . ... ||||| |.|. |. | |..| |.| ..| | ...
GvGrsGtflvidsqleraktegvsdifdflrkirsqriglvdtkeryiyihellae
|
|||||||||
subfamily_PTPN3_pd | Subfamily PTPN3 | 1341-1577 | 6.9e-43 | 141.6 | In-house | 33-272 (280) | alignment | ||
Range on Protein: 1341-1577
Range on HMM: 33-272/280.0
VTHNIASQNNDKNRSTQFLPRDNYRVPLKGEHPDYINAVFIN----GYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCHEKEIDQEVCYQYWPS
... ..| .||| || |. || || .. ||||| ..| . . . .|.. |. .|| .||.|. ..... |||| | . |.||||.
isaarkpenlsknryrdilpydatrvklkesetdyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqksslivmlttlverGrvkChqyWPe
TPSGLVIGEYAIMLSSEEIYNGYIERKLEVKNTNTGSTQSVMQYQITNWVSTRKMAKPQTILSVIEEMyKTQRRRGNTSIVVHCSDTVGRSAMFCAAATT
| | ||. .....|. . |. |.| .|...| ....| | ..| ... .|...|.. ...|. .. .||||| .||. .. . |.
tedeleygefsvkcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefverv.rklrsgkeePvvvhCsaGigrtGvlilleta
INKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVL
. . .. . . .... | |. |||..||. . . .|
lalieaaepvypldivrtmrdqramlvqtasqykfvCeail
|
|||||||||
0043147 | (Phosphotyrosine protein) phosphatases II | 1086-1285 | 7.4e-43 | 141.6 | In-house | 4-153 (172) | alignment | ||
Range on Protein: 1086-1285
Range on HMM: 4-153/172.0
QNDYINACYIDGYSQDYKYIATQGPVTKTLVDFWRLIWQERPPVIVMVTNLkedttikchqywpehgstsygpfrieltkeqvltdytirkmqltLLGSD
.||||| |.|.| ..|||||| || ||||..... .||..|.| |. .
gsdyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltel............................................lydpe
QPPLMITQYHFTSWPDHGVPeYATSILQFHRRIKN-EYKPTKGPMLVHCSAGVGRTGTFMAIDMGLqqaekeGGIDIISIINKMRQQRMKMVQTADQYIF
. .. ||....||||||| . .|.| . |.. . .||.|||||||||||||. |... | |... ... .|..|...||. .||.|
llerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml......lglsleeavalvrekRpgavqnpsqyrf
V
.
l
|
|||||||||
0049772 | (Phosphotyrosine protein) phosphatases II | 1046-1294 | 4e-42 | 140.4 | In-house | 35-281 (314) | alignment | ||
Range on Protein: 1046-1294
Range on HMM: 35-281/314.0
EHSVTIAVTPSNRPLNRFGNIVVYDdNRILLNQIPGNTdcqNDYINACYIDGYsqdYKYIATQGPVTKTLVDF----------WRLI--WQERPPVIVM-
|.....| . || ||. .|. .| || |. |... ||||| |.||. |.|||||| |.||| ||.. .. .. .|||
eltilvadlflnrdknryldilpad.nrvilpglpvsg...sdyinasyvdgf...lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivms
--------------------VTNLKEDTTIKCHQYWPEHGstsygpfrieltkeqvltdY-------TirkmqltllgsdqpPLMITQYHFTSWPDHGVP
..| . . . . ...... . .. .|. . .||...|
rdevladelsrLdaAlgKtpllildgngneptaadlellk...................eelydpelf..............erlgikylripvpDgsap
eYATSILQFHRRIKNEykPTKGPMLVHCSAGVGRTGTFMAIDMGLQQAekegGIDIISIINKMRQQRM-----KMVQTADQYIFVNDAVLESVT
...| . |.. ...|| ||||.||.||||||..... . . |... ... .|..|. .... .||.|. .|.|| .
.lledfdeflefieea..dkggpvlvHCkaGkgRtgtfvvaaylmkll....gvsleealedvrlkRpinpnpgfieqleqyefilealleylk
|
|||||||||
0049260 | (Phosphotyrosine protein) phosphatases II | 1094-1286 | 5e-42 | 138.5 | In-house | 1-143 (152) | alignment | ||
Range on Protein: 1094-1286
Range on HMM: 1-143/152.0
YIDGYSQDYKYIATQGPVTKTLVDFWRLIWQERPPVIVMVTNLKEDTTIKCHQYWpehgstsygpfrieltkeqvltdytirkmqltllgsdqpplmitQ
.|||| . ...|||||| || ||||.... .|||.|.| |.. .||.||. |
fidgyampfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi............................................q
YHFTSWPDHGVPEYATSILQFHRRIKNEYKPTKGPMLVHCSAGVGRTGTFMAIDMGLqqaekeGGIDIISIINKMRQQRMKMVQTADQYIFVN
|... |||||||. . .|.... |. .. .|| |||||||||||||..|... | |... ... .|..|...|.. .|..|.
ylhlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpgqlrfly
|
|||||||||
subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 1049-1291 | 8.8e-42 | 137.9 | In-house | 25-257 (267) | alignment | ||
Range on Protein: 1049-1291
Range on HMM: 25-257/267.0
VTIAVTPSNRPLNRFGNIVVYDDNRILLNqipgntDCQNDYINACYIDGYSQDYKYIATQGPVTKTLVDFWRLIWQERPPVIVMVTNLKEDTtIkcHQYW
.. .. |. ||. . . |||.|. | . ...|||| |..|| . ..|.||.|. .| ||. .| ... ||||..|. .| | ...|
isqsiaeknqernrlddnlpyddtrvilr......tkeeeyinasyvegyktknafivtqdplkntitdfltvihdqkvpvivlltkvftdn.i..rlfw
PEH--GSTSYGPFRIELTKEQVLTDYTIRKMQLTLlgSDQPPLMITQYHFTSWPDHGVPE-YATSIlqFHRRIKNEYKPTKGPMLVHCSAGVGRTGTFMA
| . . | . .| . |. || | ..| . .. .| |.. | . | . | ||. . |..|.||.||||.|||.
PPkmgqakkyqdltvehslekeendyqiitlelkf..knesahnvtlyyykkwnintnnkpylkpl..fgilaknqlengnrPlvvacsdGvGrsGtflv
IDMGLQQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLE
|| |..| .|| || . |.|.||. .|.| ..||.. . . |
idsqleraktegvsdifdflrkirsqriglvdtkeryiyihellae
|
|||||||||
subfamily_PTPN13_pd | Subfamily PTPN13 | 1327-1582 | 1.5e-41 | 137.5 | In-house | 16-271 (273) | alignment | ||
Range on Protein: 1327-1582
Range on HMM: 16-271/273.0
QFTVLEQVTQrPDEVTHNIASQNNDKNRSTQFLPRDNYRVPLKGEHPdYINAVFINGY--KEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCHEKE
.|. |... |... .|.|||| . || |. ||.|..| . |||| .|. |.. .|.. |. .|...||.|. ..... |.|. .|||
efkelrelkp.ldtcevgkkkenkdknryrnvlPydetrvklgdegg.yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamvtleke
IDQEVCYQYWPSTPS-GLVIGE-YAIMLSSEEIYNGYIERKLEVKNTNTGSTQSVMQYQITNWVSTRKMAKPQTILSVIEEMYKTQRrrGNTSIVVHCSD
.. | .|||.. . |.. . . . | . ..|. |.|.||....| .. |.. . ..| .... .| .. |. . |. .. ||||||
kgkvkchrywPesknkklkvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaellqfvaevrrlqt..dagPivvhcsa
TVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYLDS
.||| .. . . .. . . .|| ..... | |. | ||| .|| .....|. | |
GiGrsGtlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykailevlks
|
|||||||||
subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 1060-1291 | 1.7e-41 | 136.8 | In-house | 59-281 (290) | alignment | ||
Range on Protein: 1060-1291
Range on HMM: 59-281/290.0
LNRFGNIVVYDDNRILLNQipgntDCQNDYINACYIDGYSQdyKYIATQGPVTKTLVDFWRLIWQERPPVIVMVTNLKEDTTIKCHQYWPEHGS--TSYG
||. ..| | |..|.. . ||. | |..| .| |||....| .|.||.. ||. .|||. .| || ||.||.||. ..|
knrykdvvcndktrvilkd.....GydGdyvhanyvkGlka..mfiltqGalkdtvidiwrmvlqekvaaivmlceliedGkakceqyypekeGevltfG
PFRIELTKEQVLTDYTIRKMqLTLLGSDQP-PLMITQYHFTSWPDHGVPEYATSILQFHRRIKNeykpTKGPMLVHCSAGVGRTGTFMAIDMGLQQAEKE
. . ..|. . .|.|. |.. |. .. .. ||||. |. . ..|. | ... . ||. ||||||.||||||.||..||| .
eitvlcseeddkdaniikkt.lsvrdkdsGkehklkhlkikswpdksvalstlallrtlrilrk....asGpvvvhcsaGiGrtGtfvaievglqilldG
GGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLE
.|.. .. .|. |.. || ||. . ...|.
keldlldlvralrnsrlnsvqvdiqylalveilld
|
|||||||||
subfamily_PTPN9_pd | Subfamily PTPN9 | 1319-1580 | 1.7e-41 | 137.2 | In-house | 13-290 (297) | alignment | ||
Range on Protein: 1319-1580
Range on HMM: 13-290/297.0
TGRTGFIDQFTVLEQVTQRpDEVTHNIASQNNDKNRSTQFLPRDNYRVPLKG----EHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVT
.|. | . ... . . . .... | ||| | | |. || |. |. ||||| |..|||.||||| . |. .| ..||.|. ...|
kgkrGlskeyaeirnepve.GtflasklranleknrytdvlcydetrvvlakvdedeasdyinanfvdGykqkkafiatqGplkktvsdfWrmvWeqevl
AIVMLCHEKEIDQEVCYQYWP-STPSGLVIGEYAIMLSSEEIYNGYIERKLEVKNTNTGSTQSVMQYQITNWVSTRKMAKPQTILSVIEEMYKTQR----
||| . | . | |||| .. | |.. . . | .. | .|.||.||..|. ...|. .|.. | ...| |.|.. ..|
vivmttrvvergrlkcgqyWpleeessaefgdlsvsnveveeeedykvrvleiknvkteesrkvthfqflsWPdyGvPssaaslldvlekvrekqalavk
-----RR---GNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYL
. . |||||| .||. |.. .... ...|..||....| | |. |.|| .||. .. || |
elgdewkghpsgPPivvhcsaGiGrtGtfitldiclsrleevgtvdvvetvkllrtqrafsiqtpeqyefcylavleya
|
|||||||||
subfamily_CG7180_pd | Subfamily CG7180 | 1339-1580 | 5.8e-41 | 135.0 | In-house | 32-290 (296) | alignment | ||
Range on Protein: 1339-1580
Range on HMM: 32-290/296.0
DEVTHNIASQNNDKNRSTQFLPRDNYRVPLK---GE-HPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCHEKEIDQeVCYQYW
.. ... ..| .||| . .| |. || |. || . ||||||..... ||..|. | |. .| .||... |... |.|.|... . . . .||
gdCagglrkenreknrdvkvvPyDynRvvLekldGeeksdYinavyvdsflkkkeyivteapkketvdefWrlvydeeisavvvLtktfdfak.mypsyw
PSTPsGLVIGEYAIMLSSEEIYNGYIERKLEVKNT----------NTGSTQSVMQYQITNWVSTRKMAKP-QTILSVIEEMYKTQRRR----GNTSIVVH
| . || . . .|. | |.. .. . . | |...|.| | . |. .... ... . . ... . .||.
pnks.keqygeifveiveekqyanlkirtfkltkkivalteqekqvkaetRivklfqlteWeledkvPlstnalielrrrvrlwrekvdedpeegPvvvv
CSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYL
.|| ..|| ...|. .... . |. .|||. .| |...|. |..|..|. |....| ..
ssdGasRsGvylaidanlelvekeeevdvFeavktlrrsRpqLvenveeYkyiYdvlleav
|
|||||||||
subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 1345-1581 | 8.9e-41 | 134.6 | In-house | 16-265 (270) | alignment | ||
Range on Protein: 1345-1581
Range on HMM: 16-265/270.0
IASQNNDKNRSTQFLPRDNYRVPLKGEHPD----YINAVFINGYKE-KKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCHEKEIDQEVCYQYWPSTPS
| ... ||... || . || |. .. | |||| ...|... ||..| | .|. .| ..||.|| ...||||||. . .| .. | .|||. |
eaargkklnRyadiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepk
G---LVIGEYAIMLSSEEIYNGYIERKLEVKntNTGSTQSVMQYQITNWV------STRKMAKPQTILSVIEEMYKTQRRRGN-TSIVVHCSDTVGRSAM
| |. ... .||| .||| ..|... ..|... .. .. ..| .. . ... .|...... ..... . . ..||||. |||. .
ekvkledgkikvlalseekeegyiltrlrle..ekgeerrlvHfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcsaGvgRtGt
FCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYLD
. | .... .... .|| .... | ... ||...||. ... |..| .
lialDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyeflykavveyae
|
|||||||||
subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 1019-1291 | 2.4e-39 | 129.9 | In-house | 10-285 (305) | alignment | ||
Range on Protein: 1019-1291
Range on HMM: 10-285/305.0
GEFVANGHAKGNEGFKNQYCTLNSGDNEHSVTIAVTPSNRPLNRFGNIVVYDDNRILLnqipgNTDCQNDYINACYIDGYSQDYKYIATQGPVTKTLVDF
.|| . || .|..... ... .. . . .. ||. .. |.||. | .. .|| | |. .. ..| || |. || ||
lkfvkrtlekgpaglraefvamkrfndfekmkafkeaqeagknrykdvgcldnnrvkl.....egpwpheyihanyvstptnpkrfictqaplektcadf
WRLIWQERPPVIVMVTNLKEDTTIKCHQYWPEHGSTS----YGPFRIEL----TKEQV---LTDYTIRKMQLTLLGSDQPPLMITQYHFTSWPDHGVPEY
| . .|.. | |. ||.| . ||..|.. . . .| . ... .. .... .|.. |. . . .|.||. ||| |||
wymclqdkveaifmlcnllekgakkcleyfaskdkdvlefeekgqkisvkfessvtlkfrkdakakvtetvlviegpgekarkvthyhwidwpdrgvpaa
ATSILQFHRriknEYKPTKGPMLVHCSAGVGRTGTFMAIDMGLQQAEKEGGID-IISIINKMRQQRMKMVQTADQYIFVNDAVLE
..||.. . .|.|||. ||||||.||||. . .. |.| |. |..|.|.|| . .|| .||.|| . .|.
dlailelle....karpskgpivvhcsagigrtgsvvmleyildqllagqiiedtdkilqkireqrnnsiqtdaqylfvhqviln
|
|||||||||
subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 1031-1291 | 1.8e-38 | 126.8 | In-house | 11-267 (281) | alignment | ||
Range on Protein: 1031-1291
Range on HMM: 11-267/281.0
EGFKNQYCTLNSGDNEHSVTIAVTPSNRPLNRFGNIVVYDDNRILLNQ-IPgNTDcQNDYINACYIDGYSQDYKYIATQGPVTKTLVDFWRLIWQERPPV
. ||... | .|. | | ||. || . | |. |. .| | . ||| | || || |||| .| ||||.||||
ddfkqefsnlpgdppsdlctvfnqpvnnkknrylnipcldisrvqlkvkmp.nkn.stdyihanyirspflkrgyiltqgpkketradfwrmiwqentta
IVMVTNLKEDTTIKCHQYWPEHGSTS--YGPFRIELTKEQVLTDYTIRKMQLTLLGSdqpPLMITQYHFTSWPDHGVPEYATSILQFHRRIKNEYKptkg
|||. .. | || .|.| . . .. | ...|. | .||.. . ||| ||| . .|. |.|.
ivmlcqfletnrekcaeyfprnahcclqfdklsvsyedstvnkslvttrlnlsyege...trlithwlwkewpdwqvpessevmlkilrkirarst....
PMLVHCSAGVGRTGTFMAIDMGLQQAEKEGGI-DIISIINKMRQ-QRMKMVQTADQYIFVNDAVLE
| ..||||||||.||.||... || . || |. ..| | ||| .||... .|.
ppvihcsagvgrsgtlmaveialqsihshftlpdikqivshlrvtgraasvqtlqqymliwkvlld
|
|||||||||
subfamily_PTPN1_pd | Subfamily PTPN1 | 1343-1575 | 1.8e-38 | 127.0 | In-house | 24-266 (290) | alignment | ||
Range on Protein: 1343-1575
Range on HMM: 24-266/290.0
H--NIASQNNDKNRSTQFLPRDNYRVPLKGEHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCHEKEIDQEVCYQYWPSTPS-
. .|...|| | | |. |. .. ||||| ... . |. .|.. |. ||. ||.|. ... |.||| . | .| |.||||. .
treaklpenrnlnryrdvspydhsrikleradndyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvvekeqikcaqywPqgeee
-GLVIG--EYAIMLSSEEIYNGYIERKLEVKNTNTGSTQSVMQYQITNWVSTRKMAKPQTILSVIEEMYKTQRR-RGNTSIVVHCSDTVGRSAMFCAAAT
|.. .. . | |||... |. |.||..| .| |...... | | |.. |. . .. .. . |.||| .||| || . |
kellledtklkvkliseerksyytvrllelenlktqetreilhfhyttwpdfgvpespaaflkflfkvresGslssdvGpavihcsaGiGrsGtfclvdt
TIN---KCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQI
. | . .|. .|| | .. | .|| .| . ..
clvliekkddlssvdikkvllelrkyrlGliqtadqlrfsyla
|
|||||||||
0051082 | (Phosphotyrosine protein) phosphatases II | 1087-1289 | 1.4e-37 | 124.0 | In-house | 3-149 (151) | alignment | ||
Range on Protein: 1087-1289
Range on HMM: 3-149/151.0
NDYINACYIDGYsqdykYIATQGPVTktlvDFWRLIWQERPPVIVMVTNLKEDTtiKCHQYWPEHGstsygpfrieltkeqvltdytirkmqltllgsdq
.||||. |..|. .....|| ||..|.... .||......| .|..|.||.|
sdyinfsyvtgg.....lyrsggpla....dflellkelgiktivnlrseeerg..ycpeylpelg..................................
ppLMITQYHFTSWPDHGVPEYATSILQFHRRIKNeykPTKGPMLVHCSAGVGRTGTFMAIDMGLQQaekeggIDIISIINKMRQQRMKMVQTADQYIFVN
. ........|||.|.|.. ..|.|.. . . . .||.|||||||.|||||..|... |.. ... .... .|..|. .||. .|..|.
..ievlhipildwpdpglplsfdavleflellld...kkngpvlvHCsaGkgRTGtlvalylmllg......vsleealeeyrlkrpgvvqpnqqflfql
DAV
|.
fal
|
|||||||||
subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 1348-1581 | 1.5e-37 | 124.0 | In-house | 37-278 (287) | alignment | ||
Range on Protein: 1348-1581
Range on HMM: 37-278/287.0
QNNDKNRSTQFLPRDNYRVPL--KGEH-PDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCHEKEIDQEVCYQYWPSTPSGLVIG
. ||| .. || |. || | .||. ||||| .. .|....||| | .|. | |.||... .......... .| | . ||.||| . .|
aavkknryadvlPiddtrvllsaegelGsdyinanyvasytddeafiaaqgPiaatvrdfwravletrsasvitmtreveearlkcykywPerevPmrvG
EYAIMLSSEEIY-NGYIERKLEVKNTNTGSTQSVMQYQITNWvsTRKMAKPQ------TILSVIEEMYKTQRRRGNTSIVVHCSDTVGRSAMFCAAATTI
|...| . .| | | | . . .| .. | |... .| | . | .|.| . . .. . .|||.. .||| .. | . .
GysvvlldydikePeygvralrlidletrearvvkqldllsw..PdkvlaPtavglirfvldvkqhielardasevGPlvvhddvGiGrsGillatlvlv
NKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYLD
.. . | .|| .|. | .. . ||.| |.. ... . ||
srledlGrvdvaavvirlreyraalvqavvqlrllyealvtyyk
|
|||||||||
subfamily_PTPRN_pd | Subfamily PTPRN | 1333-1576 | 2.6e-37 | 123.1 | In-house | 40-288 (297) | alignment | ||
Range on Protein: 1333-1576
Range on HMM: 40-288/297.0
QVTQRPDEVTHNIASQNNDKNRSTQFLPRDNYRVPLKGE----HPDYINAVFINGYKEK-KAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCHEKEIDQ
. . | . | .| .||||...|| |. || || | . ||||| .| . |.| ...|. .| .||.|. .. |. ||.|.. .| .
ayeaepstkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplastvadfwqmvweqGvvvivnltrleeegv
EVCYQYWPSTPSGlVIGEYAIMLSSEEIY-NGYIERKLEVKNTNTGSTQSVMQYQITNWVSTRKMAKPQTILSVIEEMYKTQRRRGnTSIVVHCSDTVGR
. |..||| . | | . | . | || |. . |. | . .|| .| |..| |. | .. |.....| . |. | | ..||||||| .||
kqckrywpdeGse.vyhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrGrs.cpivvhcsdGaGr
SAMFCAAATTINKC-KTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIV
. .... .|. | ||. |. | |.|| |.| .|.. ... |
tGvyilidlvlnrllkGvkeidiaatlehlrdqrpglvktkdqfefaltav
|
|||||||||
PTPc_DSPc_SM00012 | 1191-1291 | 1.4e-36 | 120.2 | In-house | 2-105 (105) | alignment | |||
Range on Protein: 1191-1291
Range on HMM: 2-105/105.0
ITQYHFTSWPDHGVPEYATSILQFHRRIKNEYKPTK--GPMLVHCSAGVGRTGTFMAIDMGLQQAEKE-GGIDIISIINKMRQQRMKMVQTADQYIFVND
...||.|.||||||||...|||.. | .|.... . .|..|||||||||||||.|.|. ||| ||| . .|| |....|.||..|||| .||.|. .
vkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylflyr
AVLE
|.||
alle
|
|||||||||
subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 1029-1291 | 3.6e-36 | 119.7 | In-house | 14-275 (307) | alignment | ||
Range on Protein: 1029-1291
Range on HMM: 14-275/307.0
GNEGFKNQYCTLNSgDNEHSVTIAVTPSNRPLNRFGNIVVYDDNRILLNqIPGNTdcqNDYINACYIDGYSQDYKYIATQGPVTKTLVDFWRLIWQERPP
| . ..... | . ..||. .| ||. .. . | .||... ..| . ||| | |. . |.|..||| .| .|| .. ||.
gvqalvdefrvlak.ktpegvtveafsantdknryqdvkcqdkgrivvk.fdgla...sdyihanylgiaikpkkficaqgplentqysfwamaiqekve
VIVMVTNLKEDTTIKCHQYWPE-HGST-SYG--PFRIEL---TKEQVLTD-YTIRKMQLTLLgSDQPPLMITQYHFTSWPDHGVPEYATSILQFHRRIKN
..|. .. | . |||.|||| .| . .| | | . ... | | .| . | |... .. |||.|||. . . . ..
svimlckvielakikceqywpleegqklvfgeapntisvanlgakklapdedlinvttlkvd.waqksrtiqhlqwenwpdrgvpqinltainlleavry
EykptKGPMLVHCSAGVGRTGTFMAIDMGLQQ-AEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLE
. . |..|||||||||.|| .|| . .. . . |. .....|.|| .|| ||... .||
d....tnpvvvhcsaGvGrsGtivaislvqdkmiaGinckdmkklveelrsqrhyaiqteaqylylhrvlle
|
|||||||||
0044763 | (Phosphotyrosine protein) phosphatases II | 1070-1287 | 3.9e-36 | 119.7 | In-house | 3-165 (178) | alignment | ||
Range on Protein: 1070-1287
Range on HMM: 3-165/178.0
DDNRILLNQIPGNTDcqNDYINACYIDGYsqdyKYIATQGPvtktlVDFWRLIWQERPPVIVMVTNLKEDTTIKCHQYWPEHGStsygpfrieltkeqvl
|..| ||. ..| |||||..|... |.....| .|...|.... .||..|. .| .||..|||| .
drtrvllsnlegler..sdyinaseilpg....lylgslpp.....addlellkelgithivnlteelelgflkcdpywpeeag................
tdytirkmqltllgsdqpplmiTQYHFTSWPDHGVPEYATSILQFHRRIKNEYKPTKGPMLVHCSAGVGRTGTFMAIDMGLQQaekegGIDIISIINKMR
||... .||||||. .|.|.. |.. ... .|| ||||||||||.||..|... ... |... ..|. .|
......................iqylhipipDhgvpdllehflefvefieealdekggpvlVHCsaGvgRsgtlvaaylmkkl.....glsleeaielvr
QQRMkMVQTADQYIFVND
..|. .|.. .|. .. .
erRp.ivpnpgqlrqLye
|
|||||||||
subfamily_PTPN14_pd | Subfamily PTPN14 | 1328-1581 | 4.2e-36 | 119.5 | In-house | 26-297 (300) | alignment | ||
Range on Protein: 1328-1581
Range on HMM: 26-297/300.0
FTVLEQVTQRPDEVTHNIA--SQNNDKNRSTQFLPRDNYRVPL---KGEHPDYINAVFING--YKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLC
|| |..... . . . | .|..||| ..|| .. || | | .. .|||| |. ... .|.| .|. .| ..||.|. . .|. ||||
fteyeripkkredallstaklpenaeknrfkdvlPyednrvelsptkenstgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivmlt
HEKEIDQEVCYQYWPST---PSGLVIGEYAIMLSSEEIYNGYIERKLEVKNTNTGSTQSVMQYQITNWVSTRKMAKPQTILSVIEEMYKTQRRRGNTS--
.|.| .| ...|.|.. . . |.. .. | . .| ..|..| .. ..|. | |.| . ... || .||. .|. ...
eeeedgkeksfkyfPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseves
------IVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYLD
..||||. |||. . . |. ... .||. .||. | |. |||. ||. .......||.
keskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLreqrmllvqtlaqYkfvYkvlikylk
|
|||||||||
0051429 | (Phosphotyrosine protein) phosphatases II | 1372-1583 | 5.2e-36 | 120.1 | In-house | 3-228 (272) | alignment | ||
Range on Protein: 1372-1583
Range on HMM: 3-228/272.0
HPDYINAVFINGYKE---KKAFIIAESPMFNTARNFWKMiDDRNVTAIVMLCHEKEIDQEVCYQYWP-----------STPSGLVIGEYAIMLSSEEIYN
..|||| ...|| ..... . |. .||..||.. . ....||.|..| |.... |..||| ... .| . ..| |||...
lsgyiNardvggygrvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseelll
GYIERKLEVKNT-NTGSTQSVMQYQITNWVSTRKMAKPqtILSVIEEMYKtqrrrgNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVID--------V
|| |.|..... ..| . ||... |.|. .. .|...|.. . . ..|||| ..|.....|. . | ..| .
dyilrellltlllsagearevmhlhytdwpdhgvpqea..llellellld......ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlyl
FQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYLDSF
..... | | ||.||| .||. .....| .|.|.
eeaveelraqrpgavqteeqylflyeallellrsl
|
|||||||||
subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 1020-1290 | 1.7e-35 | 117.1 | In-house | 16-287 (310) | alignment | ||
Range on Protein: 1020-1290
Range on HMM: 16-287/310.0
EFVANGHAKGNEGFKNQYCTLNSgDNEHSVTIAVTPSNRPLNRFGNIVVYDDNRILLNqIpgNTDCQNDYINACYIDGYSQDYKYIATQGPVTKTLVDFW
.|. | ||. .|| |.. ... |.| . ||. ..|. |. |. |. | . .||| | |. .| .|||. .|..|||
nfiiateklgieglvkqyrklda.kqdssltyeaykkymhknrysdvvcldtsrvklk.i..dksryedyihanyvktnylrstficsqgplqhtiidfw
RLIWQERPPVIVMVTNLKEDTTIKCHQYWPEHGST-SYGPFRIELTKEQVlTDYTIRKMQLTLLGSD-----QP----PLMITQYHFTSWPDHGVPEYAT
|.|.||| |... . |. || ||| | | .|| |. | .. | .. .|.. . || | .. .. ||| |||.
rmifqeraesilllckvgeegrpkcvgywpslgvtetygcirvtnlsess.eefeicnlavtfvpdnvpvdeqpanlkelrvslikwpnwpdrgvpdekc
SILqfHRRIKNEYKptKGPMLVHCSAGVGRTGTFMAIDMGLQQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVL
. .|. . . .|| .||||||..|... .|... ...... .|. .. .....|.. .|| ||.... .
htv..pqrllaqvr..hgpcvvhcsagkdrlyvvvalklkidkldrglkvdaeevktellksraiciqtelqyliidrvri
|
|||||||||
subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 1050-1293 | 3.7e-35 | 116.3 | In-house | 28-270 (285) | alignment | ||
Range on Protein: 1050-1293
Range on HMM: 28-270/285.0
TIAVTPSNRPLNRFGNIVVYDDNRILLNqipgNTDcqNDYINACYIDGYSQDY-KYIATQGPVTKTLVDFWRLIWQERPPVIVMVTNLKEDTTIKCHQYW
| . .| |||. .. . .. |..|. | | ||| | .. .| ||.||||. .|| |||..|.||. ..|. | | || |.
tytayeanpdlnryadvrcieetrvvlk....nhd..rdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyy
PEHG--STSYGPFRIELT--KEQVLTDYTIRKMQLTLL-GSDQPPLMITQYHFTSWPDHGVPEYATSILQFHRRIKNeYKPTKGPMLVHCSAGVGRTGTF
||. .| . | || ||. .. . . .. . || . . . |||. || | ...... .|. .| . |. |||||||||| ||
peklgevvkfgkyeitlteckeeaiagtilnaltvintedasseplymnhvqvpwwpdqlapedarpmielykwvkk.vnpkekpicvhcsagvgrtatf
MAIDMGLQQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLESV
. || . .. |... |. .|| |.. ||. |..|. ..| .
vgidyatirimenpniemldivremramrfqavqshmqflflyvvlmeyf
|
|||||||||
subfamily_ptpA1_pd | Subfamily ptpA1 | 1056-1246 | 6.7e-34 | 112.3 | In-house | 46-249 (418) | alignment | ||
Range on Protein: 1056-1246
Range on HMM: 46-249/418.0
SNRPLNRFGNIVVYDDNRILLNQIPGNTdcQNDYINACYIDGYSqDYKYIATQGPVTKTLVDFWRLIWQERPPVIVMVTNLKEDTTIKCHQYWPEH----
| ||. ||. . |. |..| . .||||| |||| ..|.||||. .|. ||||..|..| .|||.. |. ||| .||||.
hntsknrytnilpvnhtrvqlkkiqdke..gsdyinanyidgay.pkqfictqgplpntiadfwrmvwenrcriivmlsresencrikcdrywpeqigge
-------GSTSYGPFRIELTKE--QVLTDYTIRKMQLTLLGSDQpplMITQYHFTSWPDHGVPEYATSILQFHRRIKNEY---KPT---KGPMLVHCSAG
| .| . .|| . . . |...||. | . ||||.. |||| .|... . |. . | | |. . |..||||||
qfsiygngnevfgtysvelveviqdpereiitrnirltfegetr...ditqyqyegwpdhnipdhtqpfrqllhsitnrqnqiipssdrnvpiivhcsag
VGRTGTFMAI
||||||| .
vgrtgtfcta
|
|||||||||
0036282 | (Phosphotyrosine protein) phosphatases II | 1374-1574 | 1.7e-33 | 111.1 | In-house | 3-164 (174) | alignment | ||
Range on Protein: 1374-1574
Range on HMM: 3-164/174.0
DYINAVFINGYKEKKAFIIAESPMFntarnFWKMIDDRNVTAIVMLCHEKEIDQEVCYQYWPStpsglvigeyaimlsseeiyngyierklevknTNTGS
||||| ..... . .|. |. ||.|. . ..|..|||..||| . . |..|||. . .
dyinaspldlsyitprliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe................................lredl
TQSVMQYQITNWVSTRKMAKPQtILSVIEEMYKTQRRRGNTSIVVHCSDTVGRSAMFCAAATTINKCKtEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIF
.....||. ..|. .. .|........ . . .. ..|||| |||.....|| . . |...|........| |.||.||| .||. .
erlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtpsQyrfly
Q
.
y
|
|||||||||
0041856 | (Phosphotyrosine protein) phosphatases II | 1349-1579 | 6.5e-33 | 109.2 | In-house | 1-170 (182) | alignment | ||
Range on Protein: 1349-1579
Range on HMM: 1-170/182.0
NNDKNRSTQFLPRDNYRvplkgeHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLChekeidqevCYQYWPstpsglvigeyai
| |||| . .|| |. | ..||||| .. |. . ||.. |. .| .|..|. ....|.||.|. ...|||
nldknrysdilpydhsr......dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt.........eelywp.............
mlsseeiyngyierklevkntnTGSTQSVMQYQITNWVSTRKMAkPQTILSVIEEMYKtqrrrGNTSIVVHCSDTVGRSAMFCAAATTINKckteGvIDV
. .. ..||. ..| ....|. |||... . ..|||| |||.....|| . . | ...
......................ellerlgiqylylpwpDhgvpd.ldelldfieevle.....eggpvlVHCsaGvgRtgtlvaaylmkkl....g.vsl
FQVLKSQRIQKPGSVQTVQQYQGIFQIVLTY
....| | ..||.|.| .||. . ...| .
eeavklvrsrRpgmvitpnqyfflqlallel
|
|||||||||
subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 1029-1295 | 9.2e-32 | 105.2 | In-house | 17-273 (288) | alignment | ||
Range on Protein: 1029-1295
Range on HMM: 17-273/288.0
GNEGFKNQYCTLNSGDNEHSVTIAVTPSNRplNRFGNIVVYDDNRILLNqipgnTDCqNDYINACYIDGYSQDYKYIATQGPVTKTLVDFWRLIWQERPP
. || | .| . ...... .. . | .|. |. | |. |. |. . ||.| . . . | .| |. |. .|... ..
aveglkkeyrdspneasidiidsfianptr..dryenlprcditrvkls.....ddp.dfyiaanvvssakykrrlicaqaPlngtieelWkmllesdve
VIVMVTNLKEDTTIKCHQYWPEH-GSTS-YGPFrIELTKEQVltDYTIRKMQLTLLGS---DQPPLMITQYHFTSWPDHGVPEYATSILQFHRRIKNEYK
|||...| | | .|.| . | . .| . .|.. . . ....|| . . .. . |. |.|.|||| | |.. ..|. |
yivmlcellekGkeksaeyfPsklGekarigrl.ctvvkkkr..adidklvkvsllriskegeekvivkilhlleWdddgvPenylsplrllevlkslqk
ptkgPMLVHCSAGVGRTGTFMAIDMGLQQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLESVTC
|..||.|||||||||.. | . |... . . | |...|.|..|.| .|| ||..| ||| .
....PivvhssaGvGrtgtlililialeslrlddflgirsllaklreerfkaiqtemqylyvhrcvleelll
|
|||||||||
subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 1348-1577 | 1.6e-31 | 104.4 | In-house | 2-236 (237) | alignment | ||
Range on Protein: 1348-1577
Range on HMM: 2-236/237.0
QNNDKNRSTQFLPRDNYRVPLKGE--HPDYINAVFINGYKE-KKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCHEKEIDQEVCYQYWPSTPSGLVIG
.|. ||| . | || ||| ||||| ...|. | .| |. |. .. .||.|. . . . |||| | ... |..||||| |
enkiknrygnivaydhsrvvlkgagsgsdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpstdqpaayg
EYAIMLSSEEIYNGYIERKLEVKNTNT-GSTQSVMQYQITNWVSTRKMAKPQTILSVIEEMYKTQRRRG-NTSIVVHCSDTVGRSAMFCAAATTINKCKT
... | .| . | | | . . | . . |||.| | . ..| .. . . . ..||| |||...| . . ..|
vltvslkkkeefsdytvrslllskrltlkevrlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlrqake
EGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVL
. |.|... ..| ..| .|| .|| |.| .|
kkvvdiynyvysieedrpyiiqtkdqyvfihqtil
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 1191-1325 | 6.5e-31 | 102.1 | In-house | 91-226 (440) | alignment | ||
Range on Protein: 1191-1325
Range on HMM: 91-226/440.0
ITQYHFTSWPDHGVPEYATSILQFHRRIKN-EYKPTKGPMLVHCSAGVGRTGTFMAIDMGLQQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAV
. |||. .|||.|||..| .|.. . ... . | .||.|||||||.|||| .|.| |..|.. |||.|.|| ||..| .|||| .|| ||..||
lkqyhyqgwpdkgvpkfagpvlkmiqdvnesqekagngpllvhcsagagrtgviiavdsilreakrsdqidifsfinsmrnnrpqmvqtpeqyafvheav
LESVTCGNTQVDSRNARIVFNRMSKPDTKTGRTGFI
||.. ||.| . . ... |. .| .. .
legllcgdtliledditerveqiqwpnphtdksplq
|
|||||||||
subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 1342-1583 | 1.1e-30 | 101.3 | In-house | 47-286 (290) | alignment | ||
Range on Protein: 1342-1583
Range on HMM: 47-286/290.0
THNIASQNN--DKNRSTQFLPRDNYRVPLK-GEHPDYINAVFINGYKekKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCHEKEIDQEVCYQYWPSTP
.| .| ||| . | || || | . ||. | ...| | ||... .. .|. ..|.|. . .|.|||||| | . | ||.| .
erkifdkntefkknrykdvvcndktrvilkdGydGdyvhanyvkGlk..amfiltqGalkdtvidiwrmvlqekvaaivmlceliedGkakceqyypeke
S-GLVIGEYAIMLSSEEIY-NGYIERKLEVKNTNTGSTQSVMQYQITNWVStRKMakPQTILSVIEEMYKTqrRRGNTSIVVHCSDTVGRSAMFCAAATT
| .||.... | |. . | . | |.. ..| . ..| | . . ... |... .. |. . .||||| .||. | | ..
GevltfGeitvlcseeddkdaniikktlsvrdkdsGkehklkhlkikswpd.ksv..alstlallrtlril..rkasGpvvvhcsaGiGrtGtfvaievg
InKCKTEG-VIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYLDSF
. .. ..| .|. .. .. | . .||| || . .|.| . .|
l.qilldGkeldlldlvralrnsrlnsvqvdiqylalveilldlGkdf
|
|||||||||
subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 1089-1285 | 2.7e-30 | 100.2 | In-house | 77-273 (301) | alignment | ||
Range on Protein: 1089-1285
Range on HMM: 77-273/301.0
YINACYIDGYSQDYKYIATQGPVTKTLVDFWRLIWQERPPVIVMVTNLKEDTTIKCHQYWPEHGST--SYGPFRIELTKEQVLTDYTI--RKMQLTLLGS
| | .|. . ..||||||...| ||| .. | |||... |... ||..| | . | | |.|........ . | |.....
PihanwiptsGhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkisekldigrfkikiknkelilnkkiskrtlevedstg
DQPPLMITQYHFTSWPDHGVPEYATSILQFHRRIKNeykpTKGPMLVHCSAGVGRTGTFMAIDMGLQQAEKEGGIDIISIINKMRQQRMKMVQTADQYIF
. .. .| | ...|.|.|||. . . .. .|. .. |..||||||.||. .|.. .. .. | . |.. ....|..| . ||| | .
kfatrtvthyqysewtdrgvPkshaelfdlmelvkk....sekPivvhcsaGiGrsvafigteylareveadptieltealkhlrehrwngvqtnsqlyw
V
.
m
|
|||||||||
subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 1326-1580 | 3.5e-30 | 99.7 | In-house | 24-236 (392) | alignment | ||
Range on Protein: 1326-1580
Range on HMM: 24-236/392.0
DQFTVLEQVTQRPDEVTHniASQNNDKNRSTQFLPRDNYRVPL----KGEHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCH
..| | . |. |.. | ||| . || |. || | . ||.|| .|.... .||.| ...| . .||.|. . |||.|.|. .
eefhdlpgpdiypqtvaq..keinlkknryknilpydsarvkleviddipdsdylnasyipsfdnekayiasqgpnaaslddfwrmvfqenvttiamvtk
EKEIDqevcyqywpstpsglvigeyaimlsseeiyngyierklevkntNTGSTQSVMQYQITNWVSTRKMAKPQTILSVIEEMyKTQRRRGNTSIVVHCS
|| | . ....| |...|.| . ..| .|.|. |.. . ...|||
lkegd...........................................kgddartvaqfhftewPdkdvpkhtssllkfikev.kadfGqythpliihcs
DTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYL
|||... . . . ..|. ..|||... | ..| ||| .|| |. || |
agvgrtgvvisidsvvahakktrmvdvfnfvtnirrkrpymvqtkeqyafiygavledl
|
|||||||||
subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 1320-1587 | 7.5e-30 | 99.0 | In-house | 14-286 (307) | alignment | ||
Range on Protein: 1320-1587
Range on HMM: 14-286/307.0
GRTGFIDQFTVLEQVTqrPDEVTHNIASQNNDKNRSTQFLPRDNYRVPLK--GEHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIV
| . ..|.|.|| . | |. || . | |.|||| .. .|. |. .| | ||| | .. . | || |. |. || .|| |. . .| ...
gvqalvdefrvlakkt..pegvtveafsantdknryqdvkcqdkgrivvkfdglasdyihanylgiaikpkkficaqgplentqysfwamaiqekvesvi
MLCHEKEIDQEVCYQYWPSTP-SGLVIGEYAIMLSSEEIYNGYIERKL---EVKN---TNTGSTQSVMQYQITNWVStrkMAKPQTILSVIEEMYKTqrR
|||. |. . | |||| || || . .| ... . . .| . .. .... ..| .|| ||. |. |. . . |
mlckvielakikceqywpleegqklvfgeapntisvanlgakklapdedlinvttlkvdwaqksrtiqhlqwenwpd...rgvpqinltainlleav..r
RGNTSIVVHCSDTVGRSAMFCAAATTINKC-KTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYL-DSF-ETYS
. .||||| |||| | . .| . . |. .... | |.. ..|| || . ...| |. . . |||
ydtnpvvvhcsaGvGrsGtivaislvqdkmiaGinckdmkklveelrsqrhyaiqteaqylylhrvlleyflelyketye
|
|||||||||
subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 1060-1290 | 2.5e-29 | 96.9 | In-house | 58-286 (305) | alignment | ||
Range on Protein: 1060-1290
Range on HMM: 58-286/305.0
LNRFGNIVVYDDNRILLNQIPgntdcQNDYINACYIDG-YSQDYKYIATQGPVTKTLVDFWRLIWQERPPVIVMVTNLKEDTTIKCHQYWPEHGS---TS
||. .. . | . ..|.. . ||| | |. . ..|..|||. .|. .|| .. |.. |||. . | .|| |||| .
knryqdvpcqdqsavkldkps.....psdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkveqivmlcktvelgklkcaqywpaaqgeklel
YGPFRIELTK-E-QVLTDYTIRKMQLTLLGSDQPPLMITQYHFTSWPDHGVPEYATSILQFHRRIKNeykpTKGPMLVHCSAGVGRTGTFMAIDMGLQQ-
. .| . | |. | | | . . . . ..| ||| ||| . |.. |. .| |..||||||.||||| .||. |..
ksgivvenvsgskpmerdaeiqitllnltysgdqkmsvrhlqwtewpdrgvppckltslellsairg....skvpivvhcsagigrtgtivaieyileki
AEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVL
||. . ... .|.|| .|. ||.|. .|
aenkpcppmpelvkalrdqrafsiqndvqylfihrvml
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 1044-1215 | 3.1e-29 | 96.8 | In-house | 20-190 (297) | alignment | ||
Range on Protein: 1044-1215
Range on HMM: 20-190/297.0
DNEHSVTIAVTPSNRPLNRFGNIVVYDDNRILLNQIPGntdcQNDYINACYID--GYSQDYKYIATQGPVTKTLVDFWRLIWQERPPVIVMVTNLKEDTT
. | . | .| ||. .|. .||.|. | . . ..||||| |. .|.||| .|||. .|. |||.|.... |||||..|.||
argesfssakrnsslrknryrdilatddtrvkllrvit....erdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGr
IKCHQYWPEH--GSTSYGPFRIELTKEQVlTDY-TIRKMQLTLLGSDQpPLMITQYHFTSWPDHGVPEYATSILQFH
|| |||. . | . .| . .. .. .|.|. .. ... | |||||||| . .|.
dkcapywpsvvqerlkagdvvveflssts.defdrviltelqliyrse.srvvrhvqflswpdhGvpsdledlvrfq
|
|||||||||
subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 1335-1569 | 6.2e-28 | 92.4 | In-house | 36-270 (301) | alignment | ||
Range on Protein: 1335-1569
Range on HMM: 36-270/301.0
TQRPDEVTHNIASQNNDKNRSTQF--LPRDNYRVPLKGEHpDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCHEKEIDQEVCYQ
| |..|. | ..||.| . | .| .|. | | .|. . . ||.. .|. ||. .|| |. .| ||||... | .|.| .
tidkdhitesyaylpkdkhryptvPckPstavevivdGkr.vPihanwiptsGhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekcee
YWPST-PSGLVIGEYAIMLSSEE-IYN-GYIERKLEVKNTN-TGSTQSVMQYQITNWVStRkmAKPQTILSVIEEMYKTqrRRGNTSIVVHCSDTVGRSA
| |.. .. | || . | . ..| | | ..|.|||... .|..|. || ..| | |.. . . | .. . ||||||. .|||
ylpvkisekldigrfkikiknkelilnkkiskrtlevedstgkfatrtvthyqysewtd.r..gvPkshaelfdlmelv..kksekPivvhcsaGiGrsv
MFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQY
| .. .. ... |.. . || | .. .|||..|
afigteylareveadptieltealkhlrehrwngvqtnsql
|
|||||||||
0043147 | (Phosphotyrosine protein) phosphatases II | 1371-1573 | 1.6e-27 | 91.7 | In-house | 3-154 (172) | alignment | ||
Range on Protein: 1371-1573
Range on HMM: 3-154/172.0
EHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCHEkeidqevcyqywpstpsglvigeyaimlsseeiyngyierklevKNTN
|. ||||| ....| . ||. |. || ||.|. ....|.||.|. . ..
egsdyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltel............................................lydp
TGSTQSVMQYQITNWVSTRKMaKPQTILSVIEEMYKTQRRRGNTSIVVHCSDTVGRSAMFCAAATTInkckteG-ViDVFQVLKSQRIQKPGSVQTVQQY
.. .....||. ..| .. .|...| ... . .. . ..|||| |||.....|| . . ....... | ..||.||. .||
ellerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml......lgl.sleeavalvrekRpgavqnpsqy
QGIF
. .
rfly
|
|||||||||
0048076 | (Phosphotyrosine protein) phosphatases II | 1166-1289 | 2.8e-27 | 90.5 | In-house | 22-139 (145) | alignment | ||
Range on Protein: 1166-1289
Range on HMM: 22-139/145.0
EQVLTDYTIRKMQLTLLGSDQPPLMITQYHFTSWPDHGVPEYATSILQFHRRIKNEYKPTkGPMLVHCSAGVGRTGTFMAIDMGLQqaekeGGIDIISII
. | |. |. . . ...||....|||||||. . .|.| . |.. .| ||.|||||||||||||..|... |. |... ...
lellkdlgittvlnltselellerlgiqylylpwpDhgvpdllellleflefieealkeg.gpvlVHCsaGvgRtgtlvaaylmll.....lgvsleeal
NKMRQQRMKMVQTADQYIFVNDAV
...|.||...|.. .|..|. ...
elvrsqrpgavpnpgqlrflyefe
|
|||||||||
subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 1324-1578 | 6.5e-27 | 89.0 | In-house | 22-277 (439) | alignment | ||
Range on Protein: 1324-1578
Range on HMM: 22-277/439.0
FIDQFTVLEQVtqRPD-EVTHNIASQ--NNDKNRSTQFLPRDNYRVPL----KGEHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAI
| . | .. . .|| .. ..|.| .. ||| . . | || | | |||| .|.|| ..| .| .. | .|. .||... ..... |
fkeifekinst..spdyaciaslaaqeydqtknrykdvgafdhtrvtlqeipgvphshyinanyikGyyddklyiatqgpkkettddfwrlviekktvti
VMLCHEKEidqevCYQYWPSTPSgLVIGEYAIMLSSEEIYNGYIERKLEVKNTN--TGSTQSVMQYQITNWVSTRKMAKPQTILSVIEEMYKTQRRRGNT
|||. | |.|||| . |. |. . |. | . | | | ..|.|.. . | |. .| . . .. ..
vmltnlve.....sykywpsdae.vcygdiavrvdrnielpnyvirgfkvfnerdttekertvlqfhyiawpdknvpaqashvldflrainsandkeeyg
SIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLT
.||||| |||. | .... |.| .|. ..| | |. ||.. || |.. ||
pvvvhcsagvGrtGtiialdialeqlklenkvdikgivkvlrkqrkqmvqalcqyvfiynavle
|
|||||||||
subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 1349-1577 | 6.8e-27 | 89.2 | In-house | 8-238 (239) | alignment | ||
Range on Protein: 1349-1577
Range on HMM: 8-238/239.0
NNDKNRSTQFLPRDNYRVPLK----GEHPDYINAVFINGYKE-KKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCHEKEIDQEVCYQYWPSTPSGLVi
|. ||| .. . | || |. | ||||| .. | ||.| .. . .. .||.|. . |||| | .. |.|||| . | .
nkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdstskyc.
gEYAIMLSSEEIYNGYIERKLEVKNTNTGSTQSVMQYQITNWVSTRKMAKPQTILSVIEEMYKtQRRRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTE
. . | |.. || | . . . . | ||..| | ..| . .. | . | |.||| |||. | . . ..| .
.nlrvtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitk.dslpgarpwvihcsagvgrtgaflvidamlrqakkq
GVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVL
.|.|. .|. | ..| ||| .|| |. ||
ktvdifnyvkairedrphmvqtseqyvfihlavl
|
|||||||||
subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 1349-1577 | 7.5e-27 | 89.0 | In-house | 7-237 (239) | alignment | ||
Range on Protein: 1349-1577
Range on HMM: 7-237/239.0
NNDKNRSTQFLPRDNYRVPLK----GEHPDYINAVFINGYKE-KKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCHEKEIDQEVCYQYWPSTPSGLVi
|. ||| .. . | || |. | ||||| .. | ||.| .. . .. .||.|. . |||| | .. |.|||| . | .
nkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdstskyc.
gEYAIMLSSEEIYNGYIERKLEVKNTNTGSTQSVMQYQITNWVSTRKMAKPQTILSVIEEMYKtQRRRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTE
. . | |.. || | . . . . | ||..| | ..| . .. | . | |.||| |||. | . . ..| .
.nlrvtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitk.dslpgarpwvihcsagvgrtgaflvidamlrqakkq
GVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVL
.|.|. .|. | ..| ||| .|| |. ||
ktvdifnyvkairedrphmvqtseqyvfihlavl
|
|||||||||
subfamily_egg_pd | Subfamily egg | 1033-1307 | 8.2e-27 | 88.7 | In-house | 16-287 (307) | alignment | ||
Range on Protein: 1033-1307
Range on HMM: 16-287/307.0
FKNQYCTLNSGDNEHSVTIAVTPSNRPLNRFGNIVVYDDNRILLnQIPgNTDCQNDYINACYIDGYSQDYKYIATQGPVTKTLVDFWRLIWQERPPVIVM
.. .. |. .| |.| |.. |. | . | |. | ... . .|.| | ...| ..| .| |. | ||||...||. . |||
lerrlevleesvdeislttaasdnnlekarskrvhckdssrvkl.elr.rGqylddfihanrvkGkpllnefilaqaplkntvddfwrmvfqeevqyivm
VTNLKEDttIKCHQYWPEHGSTS--Y--GPFRIELTKEQVLTDYTIRKMQLTLLGSDQPPLMITQYHFtSWPDHGvpeYATSILQFHRRIKNEYKptkgP
.| || .|. ||| | | . | .||| | . .| | .| |.|.|. . . . . . | |. |...| | |
ltsrkes..erceyywpkaesdslvtvpGslrienlkvdskadplfrvtklklvGgddeerflehwqg.dvnnss...dvysplrvlrklrnlsk....p
MLVHCSAGVGRTGTFMAIDMGLQQAEKEgGI---DIISIINKMRQQRMKMVQTADQYIFVNDAVL---ESVTCGNTQVDSRNARI
..|.. || ...|..||.. | . . | . . .|..| |... .|.|| || | ..| |
vvvqdilGvskaatlvaieiallsllrG.pitkslvlravvflrlrrrlsvesvllylfvyrlvlfffrdvigsakeldvdyerw
|
|||||||||
0046846 | (Phosphotyrosine protein) phosphatases II | 1365-1581 | 8.5e-27 | 89.4 | In-house | 4-174 (176) | alignment | ||
Range on Protein: 1365-1581
Range on HMM: 4-174/176.0
RVPLKGEHPDYINAVFINGYKekkaFIIAESPMFNTARNFWKMIDDRNVTAIVMLCHEKEIDQEVCYQYWPSTPSGLVigeyaimlsseeiyngyierkl
|.. ....||||| .| |.. .|. |. .| .|..|. . ..||.|.|. |.|... |..||| . .
rllgldldldyinanlilgsr....piatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgi......................
evkntntgstqsvmQYQITNWVSTRKMAKpQTILSVIEEMYKTQRRRgnTSIVVHCSDTVGRSAMFCAAAttinKCKTEGVIDVFQVLKSQRIQKP-GSV
||. ..|. . .|...|.... ... ..|||| .||.....|| ...| ..|...|. | |.| |.|
..............qylhlpwpDhgvpdl.elllellefirealkeg..gpvlVHCsaGigRtgtlvaay....llelekglsveealalvreqRplgav
QTVQQYQGIFQIVLTYLD
|| .||. . . .| .|.
qtpeQyrflyefellllk
|
|||||||||
0048179 | (Phosphotyrosine protein) phosphatases II | 1187-1286 | 2.3e-26 | 87.6 | In-house | 45-138 (144) | alignment | ||
Range on Protein: 1187-1286
Range on HMM: 45-138/144.0
PPLMITQYHFTSWPDHGVPEYATSILQFHRRIKNEYKpTKGPMLVHCSAGVGRTGTFMAIDMGLqqaekEGGIDIISIINKMRQQRMKMVQTADQYIFVN
. ...||....|||||||.... .|.| . |.. .. .||.|||||||||||||..|... . . |... .... .|..|. .|.. .|..|.
leregiqylhlpwpDhgvpdllellleflefieeale.eggpvlVHCsaGvgRtgtlvaaylmk.....klglsleealalvrsrrpgavpnpgqlrfLl
|
|||||||||
subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 1102-1285 | 3.3e-26 | 86.7 | In-house | 5-196 (199) | alignment | ||
Range on Protein: 1102-1285
Range on HMM: 5-196/199.0
YKYIATQGPVTKTLVDFWRLIWQERPPVIVMVTNLKEDTTIKCHQYWP--EHGSTSYGPFRIELTKEQVLTDYTIRKMQLTLLGSDQPP-LMITQYHFTS
.||||| |. .|. |||...|. |||| . . . ||| | |.. || . . . |||| . || . | |..| |||
rryiatqhplretmadfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqfts
WPDHGVPEYATS--ILQFHRRIKNEYKPTK-GPMLVHCSAGVGRTGTFMAIDMGLQQAE--KEGGIDIISIINKMRQQRMKMVQTADQYIFV
| .. |. | .. | . . |. | |..|||| | | || |.|.|.|.. | | .|.. . ...|| | .. . ..| |.
wkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfi
|
|||||||||
subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 1102-1285 | 3.8e-26 | 86.5 | In-house | 4-195 (198) | alignment | ||
Range on Protein: 1102-1285
Range on HMM: 4-195/198.0
YKYIATQGPVTKTLVDFWRLIWQERPPVIVMVTNLKEDTTIKCHQYWP--EHGSTSYGPFRIELTKEQVLTDYTIRKMQLTLLGSDQPP-LMITQYHFTS
.||||| |. .|| |||...|. |||| . . . ||| | |.. || . . . |||| . || . | |..| |||
rryiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqfts
WPDHGVPEYATS--ILQFHRRIKNEYKPTK-GPMLVHCSAGVGRTGTFMAIDMGLQQAE--KEGGIDIISIINKMRQQRMKMVQTADQYIFV
| .. |. | .. | . . |. | |..|||| | | || |.|.|.|.. | | .|.. . ...|| | .. . ..| |.
wkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfi
|
|||||||||
0049772 | (Phosphotyrosine protein) phosphatases II | 1348-1586 | 1.1e-25 | 86.5 | In-house | 45-286 (314) | alignment | ||
Range on Protein: 1348-1586
Range on HMM: 45-286/314.0
QNNDKNRSTQFLPRDnYRVPLKG---EHPDYINAVFINGYkekKAFIIAESPMFNTARNF----------WKMI--DDRNVTAIVM--------------
| ||||....|| | || |.| . ||||| ...|. ..||... |. .| .| |.|. .|.|| |||
lnrdknryldilpad.nrvilpglpvsgsdyinasyvdgf...lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivmsrdevladelsrLd
-------LCHEKEIDqevcyqywpS-----TPSGLVigeyaimlsseeiyngyI-------ErklevkntntgsTQSVMQYQITNWVStRKMAKPQTILS
|. . . .. | .. ...| ... .. ...
aAlgKtpllildgng.........neptaadlellk.................eelydpelf............erlgikylripvpD.gsaplledfde
VIEEMYKTqrrRGNTSIVVHCSDTVGRSAMFCAAATTINKCkteGViDVFQVLKSQRIQKP-----GSVQTVQQYQGIFQIVLTYLDSFETY
..| . . . .. ..|||.. .||.. |..|| . .. || .. ..|. | . | |.... .||. |....| ||. ....
flefieea...dkggpvlvHCkaGkgRtgtfvvaaylmkll...gv.sleealedvrlkRpinpnpgfieqleqyefilealleylkflkkf
|
|||||||||
0049260 | (Phosphotyrosine protein) phosphatases II | 1380-1573 | 1.3e-25 | 85.3 | In-house | 1-143 (152) | alignment | ||
Range on Protein: 1380-1573
Range on HMM: 1-143/152.0
FINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCHEKEIDQEVCYQYWpstpsglvigeyaimlsseeiyngyierklevkntntgstqsvmQ
||.||. ...||... |. ||. .||.|. . ..|.||||. . |.. . |.||. |
fidgyampfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi............................................q
YQITNWVSTRKMAKPQTILSVIEEMYKTqRRRGNTSIVVHCSDTVGRSAMFCAAATTInkckteGVIDVFQVLKSQRIQKPGSVQTVQQYQGIF
|. ..| .| .| ... . | ... . ..|||| |||.....|| . ........ | ..||.|.. .|.. ..
ylhlpwpDhgvpdlsqlllflllfiekl.aldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpgqlrfly
|
|||||||||
subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 1344-1579 | 1.9e-24 | 80.8 | In-house | 32-268 (281) | alignment | ||
Range on Protein: 1344-1579
Range on HMM: 32-268/281.0
NIASQNNDKNRSTQFLPRDNYRVPLKG-----EHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCHEKEIDQEVCYQYWPSTP
|| ||| .. | || || . ||| | .| |. .|... | .| .||.|| . | |||||||. | ..| | .|.|
fnqpvnnkknrylnipcldisrvqlkvkmpnknstdyihanyirspflkrgyiltqgpkketradfwrmiwqenttaivmlcqfletnrekcaeyfprna
-SGLVIGEYAIMLSSEEIYNGYIERKLEVknTNTGSTQSVMQYQITNWVSTRKMAKPQTILSVIEEMyktqRRRgNTSIVVHCSDTVGRSAMFCAAATTI
| . .... . . . .|.. . | |. . .. .| . . .| .. .. | | | |.||| |||| . | ..
hcclqfdklsvsyedstvnkslvttrlnl..syegetrlithwlwkewpdwqvpessevmlkilrki....rar.stppvihcsagvgrsgtlmaveial
NKCKTEG-VIDVFQVLKSQRIQ-KPGSVQTVQQYQGIFQIVLTY
. .. . |. |.. |. . ||||.||| |....| .
qsihshftlpdikqivshlrvtgraasvqtlqqymliwkvlldf
|
|||||||||
subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 1108-1285 | 6e-24 | 79.0 | In-house | 97-280 (302) | alignment | ||
Range on Protein: 1108-1285
Range on HMM: 97-280/302.0
QGPVTKTLVDFWRLIWQERPPVIVMVTNLKEDTTIKCHQYWPEH--GSTSYGPFRIELTK-EQVLTDYTIRKMQ-L-----T-LLGSDQPPLMITQYHFT
| .|| .| || | . ..| .....|| || .|. .. | .| . .. . .. | ..| .| | . .. . . .|.
ivpkkstlekhwalieqynvaivvqlcsfvedeekkcaeyysdkvggelkfgrytvktvsvktdleeftdkksfklytveiknekkkkkvkktvdilafs
SWPDHGVPEYATSILQFHRRIkNEYKptkGPMLVHCSAGVGRTGTFMAIDMGLQQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFV
.||||| |. | . |. . . || .|||||||||||||..|| |.| |. |..||. .|| | ||...| |..
awpdhGapkeaytaldilkfc.esyk...knvlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqdeqqliyl
|
|||||||||
subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 1059-1294 | 1.5e-23 | 77.9 | In-house | 45-277 (312) | alignment | ||
Range on Protein: 1059-1294
Range on HMM: 45-277/312.0
PLNRFGNIVVYDDNRILLNqipGNtdcQNDYINACYIDGYSQDYKYIATQGPVTKTLVDFWRLIWQERPPVIVMVTNLKEDTTIKCHQYWPEH-GSTSYG
|||. || ..| |. | |. .| || | .. .. ....||||. .| . ||.| |.... . ||.. || .| . |
dlnrypniqcwdrgrftla...gd...enfyihanfvkictkperfvctqgplentcthfwqlalslgstsiillcgfvedgsekcakyisdivgfvdle
PFR------IELTKE-QVLTDYTIRKMQLTLLGSDQPPlMITQYHFTSWPDHGVPEYATSILQFHRRIKNEykptKGPMLVHCSAGVGRTGTFMAIDMGL
| |. . | | ... . . | . .| ..||||||.|. . |.. .|.. | |.. |||||||||||.. |. .
dhrvyteycteieiggkskdkithrvlkvvvkatgqes.klnhyqwaswpdhgmpdscdtalrllsavkkd....kkpviahcsagvgrtgtlaliesmi
QQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLESVT
. .. . .|..| . |.. ||... .||| .
aalrhprkqnvkdsfvllrkdrarsvrvfpqyvyalrcvlefly
|
|||||||||
subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 1083-1290 | 1.7e-23 | 78.2 | In-house | 42-256 (290) | alignment | ||
Range on Protein: 1083-1290
Range on HMM: 42-256/290.0
TDCQNDYINACYIDgYSQDYKYIATQGPVTKT-------LVDFWRLIWQERPPVIVMVTNLKEDTTI----KCHQYWPEHGS--TSYGPFRIELTKEQVL
. ..||| | .. .... . |.|| | .|. . .|| .. ||. .||. . .| .. | .| ||. .. . .. ..
krfnddyiHAnrvt.cpnglrliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCakYvpesvgeelkfkgltvkCkskeke
TDYTIRKMQLTLlgSDQPPLMITQYHFTSWPDHGVPEYATSILQFHRRIKNEykptKGPMLVHCSAGVGRTGTFMAIDMGLQQAE-KEGGIDIISIINKM
| .|.. .. |. .. .| . . .| . |.| ..|. . .|.. | |..||| |. | .. ||..| | ..| . . ......
ddvetRelvvkf..ddeeeftvtHsllkgWnklnvqedtktllsliqkvkas....ktpvivHcvdGiSrsAalaaiilgyQkiaetsgsvkledvlkal
RQQRMKMVQTADQYIFVNDAVL
|.|| .....| .. || ...
rkqralaitsalelafvdagiv
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 1044-1220 | 1.1e-22 | 75.1 | In-house | 22-192 (319) | alignment | ||
Range on Protein: 1044-1220
Range on HMM: 22-192/319.0
DnehsvtiAVTPSNRPLNRFGNIVVYDDNRILLNQIPGntDCQNDYINACYIDGYSQ-DYKYIATQGPVTKTLVDFWRLIWQERPPVIVMVTNLKEDTTI
| .| .. .. .|. |.| . |. |..|. | .. |..| |. || . . |||.| . .. ||||..|. . ||| .|.| |
d.......evPvtskdksrvinvvPlPetrvvlqrigd..ddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlselGik
KCHQYWPEH----GSTSYGPFRIELTKEQVLTDYTIRKMQLTLLGSDQpPLMITQYHFtSWPDHGVPEYATSILQFHRRIKN
.| .|.| . . .|| ... | . .| | | . | . .. .| | . |.. .|| .... ....
vcaeylPtketldntslyGdilvtlkgrevkdryaistlllkrvdkee.srelthywy.kwleaevPaeeaaliamllevrs
|
|||||||||
subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 1346-1581 | 1.4e-22 | 74.8 | In-house | 45-288 (305) | alignment | ||
Range on Protein: 1346-1581
Range on HMM: 45-288/305.0
ASQNNDKNRSTQFLPRDNYRVPLKGEHP-DYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCHEKEIDQEVCYQYWPSTPSG-LVI
.|...||| . || || |.| | .|| | .. . | || ...|. .| .|| | . .| || ||| .| . |..|..| | .
eaqeagknrykdvgcldnnrvklegpwpheyihanyvstptnpkrfictqaplektcadfwymclqdkveaifmlcnllekgakkcleyfaskdkdvlef
GE--YAIML--SSEEIYNGYIERKLEVKNTN---TGSTQSVMQYQITNWVSTRKMAKPQTILSVIEEMYKTQRRRGntSIVVHCSDTVGRSAMFCAAATT
| |.. | . .. . | .|..| |. ... . . |. | . |...| . |.. .| |||||| .||.
eekgqkisvkfessvtlkfrkdakakvtetvlviegpgekarkvthyhwidwpdrgvpaadlailellekarpskg..pivvhcsagigrtgsvvmleyi
INKCKTEGVID-VFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYLD
... . .|. ..|. | |. |.|| .|| . |..| |.
ldqllagqiiedtdkilqkireqrnnsiqtdaqylfvhqvilnyfr
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 1059-1153 | 1.5e-22 | 74.8 | In-house | 49-155 (350) | alignment | ||
Range on Protein: 1059-1153
Range on HMM: 49-155/350.0
PLNRFGNIVVYDDNRILLNQIPGN------TDCQNDYINACYIDGY------SQDYKYIATQGPVTKTLVDFWRLIWQERPPVIVMVTNLKEDTTIKCHQ
||. ||. |. .|. |.. . . . |||||| |. |.||||||.|. .|. ||...| . .||...|.. | ||..
aknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcyr
YWPEHGS
||.| .
YWqegsy
|
|||||||||
subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 1338-1580 | 2.4e-22 | 74.2 | In-house | 24-270 (285) | alignment | ||
Range on Protein: 1338-1580
Range on HMM: 24-270/285.0
PDEVTHNIASQNNDKNRSTQFLPRDNYRVPLKGEHPDYINAVFIN-GYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCHEKEIDQEVCYQYWPS
| ..|. | | || .. .. || || ||| | .. |.. ..| .. |. .| .||.|| . ... ..||| | | | |.|
ppnctytayeanpdlnryadvrcieetrvvlknhdrdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyype
TPSGLV-IGEYAIMLS--SEEIYNGYIERKLEVKNTNTGSTQSV-MQYQITNWVSTrKMAkPQTILSVIeEMYKTQRR--RGNTSIVVHCSDTVGRSAMF
.| .|.| | |. || | | | | ||. |.. . |.. | ..| |. .| |.|| .. .. |.|||| |||.| |
klgevvkfgkyeitlteckeeaiagtilnaltvintedasseplymnhvqvpwwpd.qla.pedarpmi.elykwvkkvnpkekpicvhcsagvgrtatf
CAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYL
. . . |....... | . .||. |. .. ... |.
vgidyatirimenpniemldivremramrfqavqshmqflflyvvlmeyf
|
|||||||||
0051082 | (Phosphotyrosine protein) phosphatases II | 1372-1574 | 5.9e-22 | 73.3 | In-house | 2-147 (151) | alignment | ||
Range on Protein: 1372-1574
Range on HMM: 2-147/151.0
HPDYINAVFINGYkekkaFIIAESPmfntARNFWKMIDDRNVTAIVMLCHEKEIDqeVCYQYWPSTPsglvigeyaimlsseeiyngyierklevkntnt
..||||. .. |. ... | |.... . ....||.|. |.|.. |..|.|..
lsdyinfsyvtgg.....lyrsggp....ladflellkelgiktivnlrseeerg..ycpeylpelg.................................
gstQSVMQYQITNWVSTRKMAKPQTILSVIEEMYKtqrrRGNTSIVVHCSDTVGRSAMFCAAATTINKcktegvIDVFQVLKSQRIQKPGSVQTVQQYQG
|....|..| . ....|...|.. . .| ..|||| .||.....|. . . ......|. |.. ||.||. ||..
...ievlhipildwpdpglplsfdavleflellld....kkngpvlvHCsaGkgRTGtlvalylmllg......vsleealeeyrlkrpgvvqpnqqflf
IFQ
...
qlf
|
|||||||||
subfamily_ptpA1_pd | Subfamily ptpA1 | 1327-1539 | 9.5e-22 | 72.3 | In-house | 26-255 (418) | alignment | ||
Range on Protein: 1327-1539
Range on HMM: 26-255/418.0
QFTVLEQVTqRPDEVTHNIASQNNDKNRSTQFLPRDNYRVPLKG----EHPDYINAVFINGYKEkKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCHE
.| .||. | | . .| ||| |. || . || || | ||||| .|.| | || .. |. || .||.|. . . |||| .|
efrlleesv.gpsetsegdkkhntsknrytnilpvnhtrvqlkkiqdkegsdyinanyidgayp.kqfictqgplpntiadfwrmvwenrcriivmlsre
KEIDQEVCYQYWPSTPSGLvigEYAIMLSSEEIYNGY----------IERKL---EVKNTNTGSTQSVMQYQITNWVSTRKMAKPQTILSVIEEMYKTQR
| . | .||| | ...| .|.. | ||.. ... | | |. . ||| | . | . .. . . |
sencrikcdrywpeqigge...qfsiygngnevfgtysvelveviqdpereiitrnirltfegetrditqyqyegwpdhnipdhtqpfrqllhsitnrqn
R-----RGNTSIVVHCSDTVGRSAMFCAAATTINK
. | |.|||| |||. ||.| ..|
qiipssdrnvpiivhcsagvgrtgtfctavimmkk
|
|||||||||
PTPc_DSPc_SM00012 | 1477-1576 | 1.4e-21 | 72.0 | In-house | 2-103 (105) | alignment | |||
Range on Protein: 1477-1576
Range on HMM: 2-103/105.0
VMQYQITNWVSTRKMAKPQTILSVIEEMYKTQRRRG-NTSIVVHCSDTVGRSAMFCAAATTINKCKTE-GVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQ
|..|..|.| . . ... ||...... | .. .. ....|||||. |||...|.|... ......| . .|.||..|. | |.||.||| .||. . .
vkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylflyr
IV
..
al
|
|||||||||
subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 1057-1286 | 1.8e-20 | 67.6 | In-house | 51-278 (302) | alignment | ||
Range on Protein: 1057-1286
Range on HMM: 51-278/302.0
NRPLNRFGNIVVYDDNRILLNQipgntdCQNDYINACYIDGYSQDYKYIATQGPVTKTL---VDFWRLIWQERPPVIVMVTNlKEDTTIKCHQYWP-EHG
| |. .. ..|.|.. |.. ....|.|| .. . .. | .| |.... .|||...||. .|.. .|. . ....| . |
nlkknqsedvpildsnlvklea......epdsyvnaskvevPeltrsiilaQlpkvdsedsveeFWrmvfqekivsvvilvg.eeelkktlselfpkksg
-STSYGPFRIELTKEQVLTDYTiRKMQLTLLGSDQP-PLMITQYHFTSWPDHGVPEYATSILQFHRRIKNEYKPTKGPMLVHCSAGVGRTGTFMAIDMGL
. || ... | . . . . . .| . .... |..| |... ||. ... . . .. ... .... |.|| |.|.. . .
dykeygkmfvNnrkVekaeeek.tryviEvlPegcsnsvlanvyvltnWkqkkvpvkyaeliktaakvfakkikadentvivSknGaGRagafltlavav
QQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVN
.. .|. | |....|.|| ..|....||...
eklqkgkepnikeivksiRsqRpravdslkQyvsly
|
|||||||||
subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 1114-1293 | 2.2e-20 | 67.8 | In-house | 40-221 (255) | alignment | ||
Range on Protein: 1114-1293
Range on HMM: 40-221/255.0
TLVDFWRLIWQERPPVIVMVTNLKEDTTIKCHQYWPEHGSTSYGPFRIELTKEQVLTDYTIRKMQLTL-LGSDQPPLMITQYHFTSWPDHGVPEYATSIL
|. |.. | | .. |.||.....|.. ||..|.| ...| . .| .| ...|. || . .. |... |... || | ||
tvdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdeklkladvnvtttkssadvvlrtleitstlgekkkthtvkhysykGWieknaPelareil
QFHRRIKNEyKptkgPMLVHCSAGVGRTGTFMAIDMGLQ------QAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLESV
. . ... | ...||||.|.||. .|. ... | . . ...| .|.....|..| . ..| | | ||. |
nilkvvrds.k....svvvhCstGiGrsaafvlaelvyqkmirsldttetveldylslleelrskrkraihtPlqlafsilmvldlv
|
|||||||||
0044763 | (Phosphotyrosine protein) phosphatases II | 1370-1576 | 3.4e-20 | 67.9 | In-house | 15-167 (178) | alignment | ||
Range on Protein: 1370-1576
Range on HMM: 15-167/178.0
GEHPDYINAVFINGYkekkaFIIAESPMfntaRNFWKMIDDRNVTAIVMLCHEKEIDQEVCYQYWPSTPSglvigeyaimlsseeiyngyierklevknt
| |||||..| .. .... |. ...... . ..|.||.|..|.| .. |..|||. .
lersdyinaseilpg.....lylgslpp....addlellkelgithivnlteelelgflkcdpywpeeag..............................
ntgstqsvMQYQITNWVSTRKMAKPQTILSVIEEMYKTQRrRGNTSIVVHCSDTVGRSAMFCAAATTINKckteGViDVFQVLKSQRIQKPgSVQTVQQY
.||. .... .. .| ..| . . . . . ..|||| ||||....|| . |. ....... | ..| |.. |.
........iqylhipipDhgvpdllehflefvefieeald.ekggpvlVHCsaGvgRsgtlvaaylmkkl....gl.sleeaielvrerRp.ivpnpgql
QGIFQIV
. . ..
rqLyefe
|
|||||||||
subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 1346-1580 | 4e-20 | 66.7 | In-house | 52-289 (305) | alignment | ||
Range on Protein: 1346-1580
Range on HMM: 52-289/305.0
ASQNNDKNRSTQFLPRDNYRVPLKGEHP-DYINAVFING-YKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCHEKEIDQEVCYQYWPSTPSGLVI
| . ||| .. .|. | |. | ||| | .. .| || |. |. .| .|| |. ...| |||||. |. . | |||| . .
adiaitknryqdvpcqdqsavkldkpspsdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkveqivmlcktvelgklkcaqywpaaqgekle
GEYAIMLsSEEIYNGYIERKLEVKNTNT------GSTQSVMQYQITNWvstRKMAKPQTILSVIEEMYKTqrRRGNTSIVVHCSDTVGRSAMFCAAATTI
|.. . . .|| |.. | . . || . | |.| | |. .| . | . |||||| .||. | .
lksgivv.envsgskpmerdaeiqitllnltysgdqkmsvrhlqwtew...pdrgvppckltslellsai..rgskvpivvhcsagigrtgtivaieyil
NKCKTE-GVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYL
.| . . . ...|. | |. |.|. || | ...| |.
ekiaenkpcppmpelvkalrdqrafsiqndvqylfihrvmlnyf
|
|||||||||
subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 1348-1580 | 7.2e-20 | 66.2 | In-house | 42-271 (288) | alignment | ||
Range on Protein: 1348-1580
Range on HMM: 42-271/288.0
QNNDKNRSTQFLPRDNYRVPLKGEHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCHEKEIDQEVCYQYWPSTPS-GLVIGEY
.| ..| .. | || |. . ||.| . | |. .| |..|. | ..|||. . .| |||||. | .| .|.|| || .
anptrdryenlprcditrvklsddpdfyiaanvvssakykrrlicaqaPlngtieelWkmllesdveyivmlcellekGkeksaeyfPsklGekarigrl
AIMLSSEEiynGYIERKLE---VKNTNTGSTQSVM-QYQITNWVSTRKMAKPQTILSVIEEMyktqrRRGNTSIVVHCSDTVGRSAMFCAAATTINKCKT
. . |.. .. ......| .. .. . . .| . .. | ..| . . . ||||.| |||.. . .. .
ctvvkkkr...adidklvkvsllriskegeekvivkilhlleWdddgvPenylsplrllevl.....kslqkPivvhssaGvGrtgtlililialeslrl
EGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYL
. . . ..|.. | .. ..|| .|| ....|| .|
ddflgirsllaklreerfkaiqtemqylyvhrcvleel
|
|||||||||
subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 1318-1579 | 7.5e-20 | 65.7 | In-house | 23-289 (310) | alignment | ||
Range on Protein: 1318-1579
Range on HMM: 23-289/310.0
KTGRTGFIDQFTVLEqvTQRPDEVTHNIASQNNDKNRSTQFLPRDNYRVPLK---GEHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVT
| | |.. |. |. ... .|.. .. ||| .. . .|. || || . ||| | ... ...|| .. |. | .||.|| .
klgieglvkqyrkld..akqdssltyeaykkymhknrysdvvcldtsrvklkidksryedyihanyvktnylrstficsqgplqhtiidfwrmifqerae
AIVMLCHEKEIDQEVCYQYWPSTPSGLVIGEY---AIMLSSEEIYNGYIERKLEVKN---TNTGSTQSVMQYQITNWVSTRKMAKPQTILSVIEEMYKTQ
.|..||. | . | |||| | . ||||. . . | . . .. .. .| . |. . . .|
silllckvgeegrpkcvgywpslgvtetygcirvtnlsesseefeicnlavtfvpdnvpvdeqpanlkelrvslikwpnwpdrgvpdekchtvpqrllaq
RRRGNtsIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTY
| | ||||| ..| . .| .|.| . .|. .| . .. .|| || | .. . .
vrhgp..cvvhcsagkdrlyvvvalklkidkldrglkvdaeevktellksraiciqtelqyliidrvriif
|
|||||||||
subfamily_egg_pd | Subfamily egg | 1327-1580 | 1.4e-19 | 64.9 | In-house | 19-270 (307) | alignment | ||
Range on Protein: 1327-1580
Range on HMM: 19-270/307.0
QFTVLEQVTQRpDEVTHNIASQNNDKNRSTQFLPRDNYRVPLK---GEH-PDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCHE
.. |||..... .|. ... | .| || . .| || |. | . |.| | ..| ||.|..|. || .||.|. .| ||||
rlevleesvde.islttaasdnnlekarskrvhckdssrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvddfwrmvfqeevqyivmltsr
KEIdqEVCYQYWPSTPSG-LVI--GEYAIMLSSEEIYN--GYIERKLEVKNTNtgSTQSVMQYQITNWVSTRKMAKPQTILSVIeemyktqrRRGNTSIV
|| | | ||| ..| ||. | . | . . || . .. . ... .. . .. | .| . |. . .|
kes..erceyywpkaesdslvtvpGslrienlkvdskadplfrvtklklvGgd..deerflehwqgdvnnssdvysplrvlrkl........rnlskpvv
VHCSDTVGRSAMFCAAATTINKCKtEGVIDVFQVLKS---QRIQKPGSVQTVQQYQGIFQIVLTYL
|.. . | ..| . |. ... . | | . ||.. | ... ||..| .| ....|| ..
vqdilGvskaatlvaieiallsll.rGpitkslvlravvflrlrrrlsvesvllylfvyrlvlfff
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 1323-1507 | 5.1e-19 | 63.1 | In-house | 6-193 (319) | alignment | ||
Range on Protein: 1323-1507
Range on HMM: 6-193/319.0
GFIDQFTVLEQVTQRPDevthNIASQNNDKNRSTQFLPRDNYRVPL--KGEHP--DYINAVFINGYKEKKA-FIIAESPMFNTARNFWKMIDDRNVTAIV
...| | |. | | .. .||.| . .| . || | .|... |..| .. ||.. .. .| |. .. ... .||... ... ||
dvaeefrdlPqliarad....evPvtskdksrvinvvPlPetrvvlqrigdddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrviv
MLCHEKEIDQEVCYQYWPST---PSGLVIGEYAIMLSSEEIYNGYIERKLEVKNTNTGSTQSVMQYQItNWVSTRKMAKPQTILSVIEEMYKT
|. | .|| .|.|. .. . |.. . | |. . |. | .|. . .. . | .|. . |......... |. ..
qltdlselGikvcaeylPtketldntslyGdilvtlkgrevkdryaistlllkrvdkeesrelthywy.kwleaevPaeeaaliamllevrss
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 1179-1290 | 2.6e-18 | 60.9 | In-house | 207-341 (350) | alignment | ||
Range on Protein: 1179-1290
Range on HMM: 207-341/350.0
LTLLGSDqpPLMITQYHFTSWPDHGVPEYATSILQFHR--------RI-KNEYKPT-KGPMLVHCSAGVGRTGTFMAIDMGLQQ------A-EK------
.|| || |... | .. |.| .. |||| . .. .. |.|||||||||||||....|. |.. ..
itlaasd..PyvvyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldv
-EGGIDII-SIINKMRQQRMKMVQTADQYIFVNDAVL
|.| |.|..|.||..|||. ||.||. .|.|
aaktrDlisiivnelrkqrismvqnldqfifiYeall
|
|||||||||
subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 1348-1580 | 4.6e-18 | 59.7 | In-house | 50-285 (302) | alignment | ||
Range on Protein: 1348-1580
Range on HMM: 50-285/302.0
QNNDKNRSTQFLPRDNYRVPLKGEHPDYINAVFINGYKEKKAFIIAESPMFNTA---RNFWKMIDDRNVTAIVMLCHEKEIDQeVCYQYWPSTPS-GLVI
.| .||.|... |. .| |..| .|.|| .. . .. |.| | ... .||.|. ..... .|.| |.|... ...| . .
knlkknqsedvpildsnlvkleaepdsyvnaskvevPeltrsiilaQlpkvdsedsveeFWrmvfqekivsvvilvgeeelkk.tlselfpkksgdykey
GEYAIMLSSEEIYNGYI-ERKLEVKNtnTGSTQSVM--QYQITNWVSTRKMAKPQTILSVIEEMYKtQRRRGNTSIVVHCSDTVGRSAMFCAAATTINKC
|. . | .. . .|| | ..||. | .||| ... | .. ...... . .. ..|. .|| ..| ..|....|
gkmfvNnrkVekaeeektryviEvlP..egcsnsvlanvyvltnWkqkkvpvkyaeliktaakvfa.kkikadentvivSknGaGRagafltlavavekl
KTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYL
... . ...|| | |.| .|....|| .. ..|.|.
qkgkepnikeivksiRsqRpravdslkQyvslyialllyi
|
|||||||||
subfamily_hpo-7_pd | Subfamily hpo-7 | 1112-1296 | 6.6e-18 | 59.6 | In-house | 44-230 (263) | alignment | ||
Range on Protein: 1112-1296
Range on HMM: 44-230/263.0
TKTLVDFWRLIWQERPPVIVMVTNLKEDTTIKCHQYWPEHGSTSYGPFRIELTKEQVLTDYTIRKMQLTL-LGSDQPPLMITQYHFTSWPDHGVPEYATS
.|. |.. | | .. |.||... .|. || .|.| .... .| | .. .|. || . ...| .. |... || | .
vqtidkfyqtivqtktevvvmLcDfneegvekcssyfPlekdekqklanvnvcttkvqsdvllktlellstlgeKkkthtvkhysykgWiekndpelare
ILQFHRRIKNEyKptkgPMLVHCSAGVGRTGTFMAIDMGLQ------QAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLESVTCG
||. . .| | .. ||||.|.||. | ... | . . ...| .|.....|..| . ..| | | ||. |
ilnilkvarns.k....slvvhcstGiGrsaafsvaElvyqkmirsldttstveldylsLleelrssrkraihtPmqLafsilmvLdfvlnn
|
|||||||||
subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 1365-1577 | 8.4e-17 | 56.2 | In-house | 34-256 (290) | alignment | ||
Range on Protein: 1365-1577
Range on HMM: 34-256/290.0
RVPLKGE----HPDYINAVFINgYKEKKAFIIAESPMFNT-------ARNFWKMIDDRNVTAIVMLCHEKEIDQE----VCYQYWPSTPS-GLVIGEYAI
||.||| ||| | .. . . ..|. .|| .. .|| |. . .|. .|||| .| ... | .| | . | .. .
rvvLkgygkrfnddyiHAnrvt.cpnglrliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCakYvpesvgeelkfkgltv
MLSSEEIYNGYIERKLEVKNTNtGSTQSVMQYQITNWVSTRKMAKPQTILSVIEEMYKTqrrrgNTSIVVHCSDTVGRSAMFCAAATTINKCK-TEGVID
| | .. ..|.|.|| . . | ... .| .. ...|.||.|. . . .| ..||| | . |||.. | | |.| .
kCkskekeddvetRelvvkfdd.eeeftvtHsllkgWnklnvqedtktllsliqkvkas.....ktpvivHcvdGiSrsAalaaiilgyQkiaetsgsvk
VFQVLKSQRIQKPGSVQTVQQYQGIFQIVL
. .|||. | |. ... ... . ..
ledvlkalrkqralaitsalelafvdagiv
|
|||||||||
subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 1385-1575 | 1.3e-16 | 55.3 | In-house | 2-199 (199) | alignment | ||
Range on Protein: 1385-1575
Range on HMM: 2-199/199.0
KEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCHEKEIDQEVCYQYWPSTPSGlvIGEYAIMLSSE---EIYNGYIERKLEVKN--TNTGSTQSVMQ
| .. .| .. |. .| .||.|. . |||. .. . |||.| || |.|. . . | | . | | ||. . .
kgqrryiatqhplretmadfwqmvwetgsghivmvnddqknkeadypfywpttesg..tgkygslsvttktittkpdytitaliltnnttappstreish
YQITNWV--STRKMAKPQTILSVIEEMYKTQRRRGNTSIVVHCSDTVGRSAMFCAAATTIN---KCKTeGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQ
||.| | .| ..| .. |. | . .. ..||||| | . .| | . . || |.|.|.| | | . | . ..|.|. |.|
yqftswkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheeskt.svvdlfevakrlrqarcgiisslqhynfiyq
I
.
v
|
|||||||||
subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 1386-1575 | 1.7e-16 | 55.0 | In-house | 2-198 (198) | alignment | ||
Range on Protein: 1386-1575
Range on HMM: 2-198/198.0
EKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCHEKEIDQEVCYQYWPSTPSGlvIGEYAIMLSSE---EIYNGYIERKLEVKN--TNTGSTQSVMQY
.. .| .. |. .| .||.|. . |||. .. . |||.| || |.|. . . | | . | | ||. . .|
gqrryiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywpttesg..tgkygslsvttktittkpdytitaliltnnttappstreishy
QITNWV--STRKMAKPQTILSVIEEMYKTQRRRGNTSIVVHCSDTVGRSAMFCAAATTIN---KCKTeGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQI
|.| | .| ..| .. |. | . .. ..||||| | . .| | . . || |.|.|.| | | . | . ..|.|. |.|.
qftswkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheeskt.svvdlfevakrlrqarcgiisslqhynfiyqv
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 1223-1287 | 4e-16 | 53.6 | In-house | 244-309 (319) | alignment | ||
Range on Protein: 1223-1287
Range on HMM: 244-309/319.0
KPTKGPMLVHCSAGVGRTGTFMAIDMGLQQAEKE-GGIDIISIINKMRQQRMKMVQTADQYIFVND
. .||. |||| ||||||. .| |. ... |. .|| .. .|..| . |.| .|| |.
resqGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefiyk
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 1348-1440 | 2.1e-15 | 51.4 | In-house | 30-128 (297) | alignment | ||
Range on Protein: 1348-1440
Range on HMM: 30-128/297.0
QN--NDKNRSTQFLPRDNYRVPLKGEHP--DYINAVFINGYKEKK--AFIIAESPMFNTARNFWKMIDDRNVTAIVMLCHEKEIDQEVCYQYWPSTPSG
.| ||| .. | |. || |.. . ||||| .. .|.. .|.|. |. .| .||... ...| .|||... .| .. |. ||||. .
rnsslrknryrdilatddtrvkllrviterdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrdkcapywpsvvqe
|
|||||||||
subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 1332-1488 | 2.5e-15 | 50.8 | In-house | 77-233 (244) | alignment | ||
Range on Protein: 1332-1488
Range on HMM: 77-233/244.0
EQVTQRPDE--VTHNIASQNNDKNRSTQFLPRDNYRVPLK-GEH-PDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCHEKEIDQ
| ||| . . .|. ||| || | |||| | |||| |. .|... |. .|. .||||. .| | .|.| .| |.
sqniirpdpsvmkdafnpnnswknregaglpfdfnrvplskgsmgntyinasfvgclgrtaeyiltqhpladtsmdfwkmmlerhvnvlvvlgsveeede
evcyqYWP-STPSGLVIGEYAIMLSSEEIYNGYIERKLEVKNTNTGSTQSVMQYQITNWVST
||| | | . .. |. . . .||.. | |.. .||.|| |
.....ywpdseplewyeeditvtltdrdefknikasnleiesdmneshqaltmfqisnwpsd
|
|||||||||
subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 1350-1586 | 4.5e-15 | 50.1 | In-house | 44-282 (312) | alignment | ||
Range on Protein: 1350-1586
Range on HMM: 44-282/312.0
NDKNRSTQFLPRDNYRVPLKGEHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCHEKEIDQEVCYQYWPSTpSGLVI-GEYAI
.| || . | | | |. || | |.. . |.....|. ||. .||.. |.|..|| | | | .| |.| .. .
kdlnrypniqcwdrgrftlagdenfyihanfvkictkperfvctqgplentcthfwqlalslgstsiillcgfvedgsekcakyisdi.vgfvdledhrv
ML-SSEEIYNG------YIERKLEVKNTNTGSTQSVMQYQITNWVSTRKMAKPQTILSVIEEMYKTQRrrgntSIVVHCSDTVGRSAMFCAAA---TTIN
. || | | | | || . .|| . | .| | .. . | .. .. ||| |||. .. ...
yteycteieiggkskdkithrvlkvvvkatgqesklnhyqwaswpdhgmpdscdtalrllsavkkdkk.....pviahcsagvgrtgtlaliesmiaalr
KCKTEGVIDVFQVLKSQRIQkpgSVQTVQQYQGIFQIVLTYLDSFETY
. . . | |.| .|. .| . ||... || ...|| .| | |
hprkqnvkdsfvllrkdrar...svrvfpqyvyalrcvleflyskgly
|
|||||||||
subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 1342-1580 | 1.6e-14 | 48.6 | In-house | 22-221 (255) | alignment | ||
Range on Protein: 1342-1580
Range on HMM: 22-221/255.0
THNIASQNNDKNRSTQFLprdnyrvplkgehpdyinavfingykekkafiiaespmfnTARNFWKMIDDRNVTAIVMLCHEKEIDQEVCYQYWPSTPSGL
|.... ... |..... | | .|...| . . .|||| .| ..| | .|.| .
tehvkPekdkkrknlysl........................................tvdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdek
VIGEYAIMLSSEeIYNGYIERKLEVKNTNT--GSTQSVMQYQITNWVSTRKMAKPQTILSVIeemyKTQRRRgnTSIVVHCSDTVGRSAMFCAAATTIN-
. . . ... . . | ||. | . |. | |. . |. .. || .. | | |.||||| .|||| | |
lkladvnvtttk.ssadvvlrtleitstlgekkkthtvkhysykGWieknaPelareilnil....kvvrds..ksvvvhCstGiGrsaafvlaelvyqk
------KCKTeGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYL
. .| . .| ..|. | .......| | . .||...
mirsldttet.veldylslleelrskrkraihtPlqlafsilmvldlv
|
|||||||||
subfamily_Sponge-PTP-7_pd | Subfamily Sponge-PTP-7 | 1229-1296 | 2e-14 | 47.7 | In-house | 1-68 (69) | alignment | ||
Range on Protein: 1229-1296
Range on HMM: 1-68/69.0
MLVHCSAGVGRTGTFMAIDMGLQQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLESVTCG
|.||||.| ||||||.|| . . . | .|| .. ||. | || .|||. ||. |.. |
mvvhcssgtgrtgtfiaimvemarikseklvdifnnvqymrkcrpmmvmneieyifihdalvealklG
|
|||||||||
0048076 | (Phosphotyrosine protein) phosphatases II | 1433-1577 | 3.7e-14 | 48.1 | In-house | 2-140 (145) | alignment | ||
Range on Protein: 1433-1577
Range on HMM: 2-140/145.0
YWPST-PSGLVIGEYAIMLSSEEIYNGYIERKLEVKNTNTGSTQSVMQYQITNWVSTRKMAKPQTILSVIEEMYKTQRRrgNTSIVVHCSDTVGRSAMFC
|||| || .| . |. |.. . | . | . .. .. .. ..||. ..| ....|...| . . ... . ..|||| |||.....
ywpseilpglylgslptaldlellkdlgittvlnltselellerlgiqylylpwpDhgvpdllellleflefieealke..ggpvlVHCsaGvgRtgtlv
AAATTINkcktEGvIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVL
|| . .| ......|. | | ||.|....|.. ... .|
aaylmll....lg.vsleealelvrsqrpgavpnpgqlrflyefel
|
|||||||||
subfamily_hpo-7_pd | Subfamily hpo-7 | 1392-1579 | 5.8e-14 | 46.6 | In-house | 42-226 (263) | alignment | ||
Range on Protein: 1392-1579
Range on HMM: 42-226/263.0
IaespMFNTARNFWKMIDDRNVTAIVMLCHEKEIDQEVCYQYWPSTPSGLVIGEyAIMLSSEEIYNGYIERKLEVKNT--NTGSTQSVMQYQITNWVSTR
. . .| .|...| . . .|||| .| ..| | .|.| . . . . ... .. . . . ||. .| . |. | .|. . |. ..
l....lvqtidkfyqtivqtktevvvmLcDfneegvekcssyfPlekdekqkla.nvnvcttkvqsdvllktlellstlgeKkkthtvkhysykgWiekn
KMAKPQTILSVIEEMyktqrrRGNTSIVVHCSDTVGRSAMFCAAATTIN-------KCKTeGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTY
... || ... |. |.||||| .|||| | | . . .| . .| ..|. | .......| | . .||..
dpelareilnilkva......rnskslvvhcstGiGrsaafsvaElvyqkmirsldttst.veldylsLleelrssrkraihtPmqLafsilmvLdf
|
|||||||||
subfamily_Sponge-PTP7_pd | Subfamily Sponge-PTP7 | 1231-1296 | 8.2e-14 | 45.7 | In-house | 2-67 (69) | alignment | ||
Range on Protein: 1231-1296
Range on HMM: 2-67/69.0
VHCSAGVGRTGTFMAIDMGLQQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLESVTCG
||||.| ||||||.|| . . . | .|| .. ||. | || ..|.|. ||. |.. |
vhcssGtGrtGtfiaimvemarikseklvdifnnvqymrkcrpmmvmneneymfihdalvealklG
|
|||||||||
fn3 | Fibronectin type III domain | 469-551 | 1.2e-13 | 44.1 | Pfam-A | 2-82 (85) | alignment | ||
Range on Protein: 469-551
Range on HMM: 2-82/85.0
PVGDVIFSSVESVSMTVSWDEVPcnGRNGPITGYYLTYTNITSNT-SYTVNITGGDNrMYNLNGLIPYTNYTVSIVPYNYNMTG
..... .|.| | |.|.||.. . ..|||||| ..| . ... . ...... . ..|.|| |.|.|.... .| . .|
aPenlsvsevtstsltlsWsppk..dgggpitgYeveyrekgggeewkeftvprttt.svtltgLkpgteYefrVqavngageg
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 1223-1293 | 1.4e-13 | 45.3 | In-house | 225-295 (297) | alignment | ||
Range on Protein: 1223-1293
Range on HMM: 225-295/297.0
KPTKGPMLVHCSAGVGRTGTFMAIDMGLQQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLESV
.| . ..||||||||||.| . |. |.. |. |. .|....|.|| ..||| .|. .. ||||. .
mprnayllvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqtleqfellydavlkkl
|
|||||||||
fn3 | Fibronectin type III domain | 576-646 | 2.6e-13 | 43.1 | Pfam-A | 12-84 (85) | alignment | ||
Range on Protein: 576-646
Range on HMM: 12-84/85.0
TLTEIIIAWNPPTIPNGIITVYEIRYRESTSTG-PYSITNTTNT-YYSILGLIPNTSYTIGVRAYTSIGPGEW
| |.. . |.||. ..| || ||..|||..... . ..|.. .| . . || |.|.|.. |.|.. | |..
tstsltlsWsppkdgggpitgYeveyrekgggeewkeftvprtttsvtltgLkpgteYefrVqavngagegpe
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 1085-1161 | 2.6e-13 | 44.0 | In-house | 88-163 (349) | alignment | ||
Range on Protein: 1085-1161
Range on HMM: 88-163/349.0
CQNDYINACYID--GYSQDYKYIATQGPVTKTLVDFWRLIWQERPPVIVMVTNLKEDTTIKCHQYWPEhgsTSYGPFRI
.||||| |. .| . |||||| |. |. ||...| .. .... ... || . ||..|| | || ...
klddyinanylkltrisvekkyiatqaPlPstvddfykvillngvklvlsLnddkelslekcdiywqe...lsysnitv
|
|||||||||
I-set | Immunoglobulin I-set domain | 905-991 | 4.2e-13 | 40.9 | Pfam-A | 1-90 (90) | alignment | ||
Range on Protein: 905-991
Range on HMM: 1-90/90.0
PVIEEFPSNKTTEEGCQVLFKVKVKETLKLSFNWYHNGEPVTDDYAHELRGDG---SLLLVSVEEKHKGTYRFVANNDAGTVSQQVVLTV
|.... ... ...|| .| ....|... ..|..|...|.... . .... .. .| . .||.. .|.|. .|.| ||...... |.|
pkftqklkdvevseGesvelectveGepepsvsWakdgselkssqrvkvtveeaeytLtIsnvevsDeGkYtckatnsagkaeakaeLkV
|
|||||||||
subfamily_Sponge-PTP3_pd | Subfamily Sponge-PTP3 | 1013-1109 | 5.4e-13 | 43.0 | In-house | 5-95 (95) | alignment | ||
Range on Protein: 1013-1109
Range on HMM: 5-95/95.0
IPVGQFGEFVANGHAKGNEGFKNQYCTLNSGdNEHSVTIAVTPSNRPLNRFGNIVVYDDNRILLNqipgnTDCQNDYINACYIDGYSQDYKYIATQG
| | | | . |.. .. | |.. ... . |. . .| | ||| ||. || |. | | . ||||||..|||.. |||.||
ihvsvfhshvlemhsnsdqefdnefksismt.sgapytvgsseanipknrflnifpydatrvvlt.....tkrdsdyinacfvdgyarkncyiaaqg
|
|||||||||
0048179 | (Phosphotyrosine protein) phosphatases II | 1406-1573 | 7.9e-13 | 43.8 | In-house | 23-138 (144) | alignment | ||
Range on Protein: 1406-1573
Range on HMM: 23-138/144.0
KMIDDRNVTAIVMLCHEKEIDQEVCYqywpstpsglvigeyaimlsseeiyngyierklevkntntgstqsVMQYQITNWVSTRKMAKPQTILSVIEEMY
... . ..|... |..| | . . .. ..||. ..| .. .|...| .
ellkklgittvinlteeyepeflere.............................................giqylhlpwpDhgvpdllellleflefie
KTQRrrGNTSIVVHCSDTVGRSAMFCAAATTInkckTEGvIDVFQVLKSQRIQKPGSVQTVQQYQGIF
. .. . ..|||| |||.....|| . ..| ......|. | . ||.|.. .|.. .
eale..eggpvlVHCsaGvgRtgtlvaaylmk....klg.lsleealalvrsrrpgavpnpgqlrfLl
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 1187-1291 | 1.8e-12 | 41.2 | In-house | 216-342 (349) | alignment | ||
Range on Protein: 1187-1291
Range on HMM: 216-342/349.0
PPLMITQYHFTSWPDHGVPEYATSILQFHRrIKNE----------YK-PTKGPMLVHCSAGVGRTGTFMAIDMGLQ---QAEKE--------GGIDIIS-
| .. | . |.| .. |||| .||. .. ..||||||| ||||... .|. |. ..| |.||
kPyellqlqvknwldlslllnPisilqale.vkndliddlfarlyldtdqlstllvhcsaGcGrtGvlvtldlllsileplqnesnkiklqallkDlisi
IINKMRQQRMKMVQTADQYIFVNDAVLE
|.|..|.||. ||| |.|.. .|.|.
ivnelrkqrismvqnlaqfiaiyealLk
|
|||||||||
subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 1393-1573 | 2e-12 | 41.2 | In-house | 96-281 (302) | alignment | ||
Range on Protein: 1393-1573
Range on HMM: 96-281/302.0
AESPMFNTARNFWKMIDDRNVTAIVMLCHEKEIDQEVCYQYWPSTPSG-LVIGEYAIML-SSEEIYNGYIERK------LEVKNTNTGS--TQSVMQYQI
| .| .| .|.. ||. .| ||. .| ... | .|. | | |.|.. | .. . . ..| .|.||... . ..| .
pivpkkstlekhwalieqynvaivvqlcsfvedeekkcaeyysdkvggelkfgrytvktvsvktdleeftdkksfklytveiknekkkkkvkktvdilaf
TNWVSTRKMAKPQTILSVIE--EMYKtqrrrgnTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIF
. | ....| | .. | || ....|||| |||. . | |. |... | |. .... | . |.||. || ..
sawpdhGapkeaytaldilkfcesyk.......knvlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqdeqqliyll
|
|||||||||
subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 1056-1293 | 3.5e-12 | 40.5 | In-house | 46-279 (303) | alignment | ||
Range on Protein: 1056-1293
Range on HMM: 46-279/303.0
SNRPLNRFGNIVVYDDNRILLnqipgnTDcqNDYINACYIDGYSQDyKYIATQGPVTKTLVDFWRLIWQERPPVIVMVTNLKEDTTIKCHQYWPEHGST-
.| ||| .... | .. | .| || | |.. |. | | || |...| |||..| ... ..... | .. . .|.
knmdknrfvdvicldhskvkl......sd..ssyihasyleldssk.kailtqlplshtaadfwqmiieqkvkcvlllltdseydklggdsvfprnqdfl
SYG--PFRIELTKEQVLTDYTIRKMQLTLLGSDQPplMITQYHFTSWPDHGVPE-----YATSILQFHRRIKnEYKPTKGPMLVHCsAGVGRTGTFMAID
. |. |. |.| |. |. . .. .|. .|| .| . | | .. | ... .. . .|.||.||| ..
kfeersirvgefkrvelgdgwvlkvlsvsngdyks..flhvhhykawphnsipsdgspkfvkqiwqlqsvlr.kysdstptvymsl.sgcgragtfalfe
MG-LQQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLESV
| ... .|.. ....|. |.. || |. .| . | |
tahlslhseqasldlvkclenvrngrlhavqnlsqfsvvytllaehv
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 1475-1580 | 4.4e-12 | 40.0 | In-house | 89-194 (440) | alignment | ||
Range on Protein: 1475-1580
Range on HMM: 89-194/440.0
QSVMQYQITNWVSTRKMAKPQTILSVIEEMYKTQRRRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQ
... ||. | .| .|... ..| . || ..|||| .||... | . . ..| ||.| ...| | ..| ||| .|| ...
rtlkqyhyqgwpdkgvpkfagpvlkmiqdvnesqekagngpllvhcsagagrtgviiavdsilreakrsdqidifsfinsmrnnrpqmvqtpeqyafvhe
IVLTYL
|| |
avlegl
|
|||||||||
subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 1334-1576 | 1.1e-11 | 38.9 | In-house | 31-275 (303) | alignment | ||
Range on Protein: 1334-1576
Range on HMM: 31-275/303.0
V-TQRPDEVTHNIASQNNDKNRSTQFLPRDNYRVPLKgeHPDYINAVFINGYKEKKAfIIAESPMFNTARNFWKMIDDRNVTAIVMLCHEKEIDQEVCYQ
| . | .|..| .| |||| .. . | .| | || | ... .||| |... |. || .||.|| ...| ...| . | |.
vvsylppsvsknqfvknmdknrfvdvicldhskvkls..dssyihasyleldsskka.iltqlplshtaadfwqmiieqkvkcvlllltdseydklggds
YWPSTPSGLVIGEYAIMLS---SEEIYNGYIERKLEVKNTNTGSTQSVMQYQITNWVSTRKMAKPQTIlSVIEEMYKTQRRRGNTSIVVHCS-DTVGRSA
.| | . | .| . |. .|. . | | | . | | .|. | . |. . | .. |. ... |. | .||.
vfprnqdflkfeersirvgefkrvelgdgwvlkvlsvsngdyksflhvhhykawphnsipsdgspkfv.kqiwqlqsvlrkysdstptvymslsgcgrag
MFCAAATTINKCK-TEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIV
|. |. . . .|. ..|. | . .|| . |. .. ..
tfalfetahlslhseqasldlvkclenvrngrlhavqnlsqfsvvytll
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 1348-1436 | 4.1e-11 | 37.2 | In-house | 46-152 (350) | alignment | ||
Range on Protein: 1348-1436
Range on HMM: 46-152/350.0
QNNDKNRSTQFLPRDNYRVPLK------------GEHPDYINAVFINGY----KEKKAF--IIAESPMFNTARNFWKMIDDRNVTAIVMLCHEKEIDQEV
. ||| .. || . || || . ||||| ... . . | | . .|. .| .|.|.| .|. |..| . | . |
elfaknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlek
CYQYWPS
||.||.
cyrYWqe
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 1096-1166 | 6.5e-11 | 36.2 | In-house | 230-298 (440) | alignment | ||
Range on Protein: 1096-1166
Range on HMM: 230-298/440.0
DGYSQDYKYIATQGPVTKTLVDFWRLIWQERPPVIVMVTNLKEDTtikCHQYWPE-HGSTSYGPFRIELTKE
.|||. .|||| |. |..|||||. . | |.|. .|.. | | ||| | ..||| .
egyskknafiatqmpldstvldfwrlvhdyristiimlnqlndkt...csiywpvntrsvtfgpftvghkgs
|
|||||||||
subfamily_Sponge-PTP-4_pd | Subfamily Sponge-PTP-4 | 1372-1488 | 2e-10 | 35.1 | In-house | 12-124 (130) | alignment | ||
Range on Protein: 1372-1488
Range on HMM: 12-124/130.0
HPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCHEKEIDQevcyqYWPST-PSGLVIGEYAIMLSSEEIYNGYIERKLEVKNTN
.|||| |. . .. .. |. .|. .||||. .| | .|.| .| |. ||| . | . . |. . .. .||...
gntyinasfvGllgrtaeylltqhpladtsmdfwkmmleryvnvlvvlgsveeede.....ywpdsePlewyeediivtltdrdefknikasnleiesdl
TGSTQSVMQYQITNWVST
| |.. .||.|| |
neshqaltmfqisnwpsd
|
|||||||||
subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 1050-1151 | 3.9e-10 | 33.8 | In-house | 89-181 (244) | alignment | ||
Range on Protein: 1050-1151
Range on HMM: 89-181/244.0
TIAVTPSNRPLNRFGNIVVYDDNRILLNQipgnTDCQNDYINACYIDGYSQDYKYIATQGPVTKTLVDFWRLIWQERPPVIVMVTNLKEDttikcHQYWP
|. |.| || | . .| ||. |.. | |||| .. . .|| || |.. | .|||... . |.|.. ..|. .|||
kdafnpnnswknregaglpfdfnrvplsk....gsmgntyinasfvgclgrtaeyiltqhpladtsmdfwkmmlerhvnvlvvlgsveee.....deywp
EH
.
ds
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 1381-1485 | 3.9e-10 | 33.6 | In-house | 229-328 (440) | alignment | ||
Range on Protein: 1381-1485
Range on HMM: 229-328/440.0
INGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLcheKEIDQEVCYQYWPSTPSGLVIGEYAIMLSSEEIYNGYIERKLEVKNTNtgSTQSVMQY
..|| |.||| .. |. | .||... | ....|.|| ..... | ||| . .| ... | | | ||.| . . . |.
fegyskknafiatqmpldstvldfwrlvhdyristiiml...nqlndktcsiywpvntrsvtfgpftvghkgsenmnrvkvrtlelkyke..evheirqf
QITNW
.. |
evqtw
|
|||||||||
subfamily_eak_pd | Subfamily eak | 1049-1217 | 5.7e-10 | 33.1 | In-house | 42-206 (332) | alignment | ||
Range on Protein: 1049-1217
Range on HMM: 42-206/332.0
VTIAVTPSNRPLNR-FGNIVVYDDNRILLNQIPGNtdcQNDYINACYIDGYSQDYKYIATQGPVTKTLVDFWRLIWQERPPVIVMVTNLKEDTTIKCHQY
.| .| .|| .|| || . . | | .. |||| .. ||| | . . . ||... ... | ||.. . | | .|
lsisetarleavnrnvvkivpydrylvrltssqln...rlGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledvelkleksdky
WPEHG--STSYGPFRIELtKEQVLTD-YTIRKMQLTllgSDQPPLMITQYHFTSWPDHGVPEYAtSILQFHRR
.|... ..| . .| || | . . |...|. . |.. | . .| | | ...
fpdktreelkfGildver.kefvkrniletrllels...kGnethrvlhykvfGwtettlpkye.dflalrkv
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 1505-1579 | 1e-09 | 32.7 | In-house | 221-294 (297) | alignment | ||
Range on Protein: 1505-1579
Range on HMM: 221-294/297.0
YKTQRRRgNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTY
.... | |. ..|||| |||| . . . ..| . . . || .|. | |.. |||..|.. ....||
lraempr.nayllvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqtleqfellydavlkk
|
|||||||||
subfamily_Cele-PTP-5_pd | Subfamily Cele-PTP-5 | 1390-1580 | 5.8e-09 | 29.0 | In-house | 117-309 (346) | alignment | ||
Range on Protein: 1390-1580
Range on HMM: 117-309/346.0
FIIAESPMFNT---ARNFWKMIDDRNVTAIVMLCHEKEIDQEVCYQYWPSTPSGLVIGEYAIMLSSEEIYNGYIERKLEVKNtnTGSTQSVMqYQI---T
.|.|. | .. .|| || . .. . .. . . . . | | .. | .|| | ..||. |. .
livaqlpqmenesfvedfwymiyqeqihlvylmvpddklkntttslfndenggyqytgkmfinnrradvsgdpkeytievlp..egnsdsvi.cqvhhha
NWVSTRKMAKPQTILSVIEEMYkTQRRRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYL
| .. | |. .| ... .... |. . | ||. | | .||. ......|. . |.||.|.. || .|. ||. |.
pwkhlqqppktlpiikmihqfl.sekqvqnagvcvvslfgcgracsfigalyainqlnngiepniceimknikqqrpggvesfaqyasiyaivfdyi
|
|||||||||
subfamily_Cele-PTP-12_pd | Subfamily Cele-PTP-12 | 1057-1139 | 1e-08 | 29.0 | In-house | 34-113 (332) | alignment | ||
Range on Protein: 1057-1139
Range on HMM: 34-113/332.0
NRPLNRFGNIVVYDDNRILLNqiPgnTDCQNDYINACYIDGYSQDYKYIATQGPVT-KTLVDFWRLIWQERPPVIVMVTNLKED
| .|| . ..| .|. | | | ..|. || ..||||. || .| |. .| |||.. . .| .|... .. |
nmdmnriphlycfdhsrvela..p..qdgkddfynaswvdgyskksayifaqapfndhteyvfwrmvserkpsmilvfgdidek
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 1013-1098 | 1.2e-08 | 28.8 | In-house | 6-86 (440) | alignment | ||
Range on Protein: 1013-1098
Range on HMM: 6-86/440.0
IPVGQFGEFVANGhaKGNEGFKNQYCTLNSGDNEHSvTIAVTPSNRPLNRFGNIVVYDDNRILLNQIPGNTDcqNDYINACYIDGY
| | .| ..| | . |..... | || . | || |.|. ||. ||..|| .|..|... | | .||||| ||.|
iivadfadyvqnn..rrsrafedewsllpsglsqps.diaslpnnkvknryrnilaydhsrvmleevkgvpd..sdyinasyingi
|
|||||||||
subfamily_eak_pd | Subfamily eak | 1351-1504 | 1.9e-08 | 28.1 | In-house | 54-207 (332) | alignment | ||
Range on Protein: 1351-1504
Range on HMM: 54-207/332.0
DKNrSTQFLPRDNYRVPLKG---EHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCHEKEIDQEVCYQYWPSTP-SGLVIGEY
..| . .|.| | | | .. |||| .. . . .|.. . . ||.|. ... |||.| .. | . | .|.| | | .
nrn.vvkivpydrylvrltssqlnrlGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledvelkleksdkyfpdktreelkfGil
AIMLSSEeIYNGYI-ERKLEVKNTNtgSTQSVMQYQITNWVSTRkMAKPQTILSVIEEM
. . . .. . |.||.. | | |. |.. | | . | . |.. . |
dverkef.vkrniletrllelskGn..ethrvlhykvfGwtett.lpkyedflalrkvm
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 1510-1579 | 4.3e-08 | 27.2 | In-house | 244-314 (319) | alignment | ||
Range on Protein: 1510-1579
Range on HMM: 244-314/319.0
RRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTE-GVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTY
| . .|||||| |||. . |. .|.. .. .|. |.. | | .. .|.|..||. |.... |
resqGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefiykvlsey
|
|||||||||
0038934 | (Phosphotyrosine protein) phosphatases II | 1193-1278 | 1.1e-07 | 27.2 | In-house | 81-162 (194) | alignment | ||
Range on Protein: 1193-1278
Range on HMM: 81-162/194.0
QYHFTSWPDHGVPEYATSILQFHRRIKNEYKP-TKGPMLVHCSAGVGRTGTFMAIDMGLQqaekeGGIDIISIINKMRQQRMKMVQT
.|. .||.|.. .|.| . .. .. ..| .||| ||.|||||. | . |.. |. .|. | .....
eylklpfpddgtvPsleillrfldlvdeflnedpggvvaVHCkaGlgRtGtlvaaYLiyr.....lgmsaeeAialfrekRpgaipn
|
|||||||||
subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 1337-1421 | 1.4e-07 | 25.4 | In-house | 25-118 (347) | alignment | ||
Range on Protein: 1337-1421
Range on HMM: 25-118/347.0
RPDEVTHNIASQNNDKNRSTQFLPRDNYRVPLKGEH---------PDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCH
| ..| . .. .|||| . |. || | |. |||| |. . .| .|... |. .| |.||||. .|| .| .
spskftsvewekslsknrskdvklidatrvvlspeksknsraddvetyinashikfdnaskeyiltqyplpdtvrdfwkmvsvtkvtqvvtife
|
|||||||||
subfamily_PTPDC1_pd | Subfamily PTPDC1 | 1194-1287 | 3.1e-07 | 25.0 | In-house | 85-170 (182) | alignment | ||
Range on Protein: 1194-1287
Range on HMM: 85-170/182.0
YHFTSWPDHGVPEYaTSILQFHRRIKNEYKptKGPMLVHCSAGVGRTGTFMAIDMGLQQAekeggIDIISIINKMRQQRMKMVQTADQYIFVND
.. .|.|.||. ..||. . .. . .| . ||| || |||| .| . .. .. |...|..| | .|| .| .|..
vynfgwkDygvasl.eriLdivkvvafalq..egkvavhChaGlGrtGvliacylvyakr.....ltaekaiklvrskrpksiqtreqvelvke
|
|||||||||
subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 1061-1143 | 3.2e-07 | 24.2 | In-house | 41-126 (347) | alignment | ||
Range on Protein: 1061-1143
Range on HMM: 41-126/347.0
NRFGNIVVYDDNRILLN---QIPGNTDCQNDYINACYIDGYSQDYKYIATQGPVTKTLVDFWRLIWQERPPVIVMVTNLKEDTTIK
|| . . |. |..| ...| . |||| .| . .|| || |. .|. |||... . .| . . ..| .|.
nrskdvklidatrvvlspeksknsraddvetyinashikfdnaskeyiltqyplpdtvrdfwkmvsvtkvtqvvtifepikdeaie
|
|||||||||
subfamily_Cele-PTP-12_pd | Subfamily Cele-PTP-12 | 1348-1420 | 6.6e-07 | 23.1 | In-house | 33-108 (332) | alignment | ||
Range on Protein: 1348-1420
Range on HMM: 33-108/332.0
QNNDKNRSTQFLPRDNYRVPLKGE--HPDYINAVFINGYKEKKAFIIAESPMFN-TARNFWKMIDDRNVTAIVMLC
.| | || .. | || | . . |. || ...|| .| |.|.|..|. . | ||.|. .|. . |...
nnmdmnriphlycfdhsrvelapqdgkddfynaswvdgyskksayifaqapfndhteyvfwrmvserkpsmilvfg
|
|||||||||
TMEM154 | TMEM154 protein family | 776-855 | 7.2e-07 | 20.6 | Pfam-A | 22-90 (146) | alignment | ||
Range on Protein: 776-855
Range on HMM: 22-90/146.0
ViqastliqtSTVMQASTSHTSGTPVTTSAPSSNPTESSAGGSSTsaiAAGIIVPLLLL-IIIVIVIIVVVVSKKKKGKHE
| .. ||..... ...... . . .| || . ||.|...| .....|.|.|.. |.|. |.|
v.........tastlasvtdpetlsanvnleegelseksadqael...vlmiiiPsvvLillllvvvilvikkkrkrrKqe
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 1369-1436 | 9.9e-07 | 22.4 | In-house | 86-155 (349) | alignment | ||
Range on Protein: 1369-1436
Range on HMM: 86-155/349.0
KGEHPDYINAVFIN--GYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCHEKEIDQEVCYQYWPS
| ||||| ... .. .| .| |. | .|.|.| .| .. | ..|| . | |..||
sgklddyinanylkltrisvekkyiatqaPlPstvddfykvillngvklvlsLnddkelslekcdiywqe
|
|||||||||
subfamily_Cele-PTP-5_pd | Subfamily Cele-PTP-5 | 1102-1292 | 2e-06 | 20.7 | In-house | 115-308 (346) | alignment | ||
Range on Protein: 1102-1292
Range on HMM: 115-308/346.0
YKYIATQGPVTK---TLVDFWRLIWQERPP-VIVMVTNLKEDTTIKChQYWPEHGSTSY-GPFRIELTKEQVLTDYTIRKMQltLLGSDQPPLMITQ-YH
.| | .| | . . ||| .|.||. | .|| . | | . | | | | . |. . .| | .. .| . .| | .|
hklivaqlpqmenesfvedfwymiyqeqihlvylmvpddklknttts.lfndenggyqytgkmfinnrradvsgdpkeytie..vlpegnsdsvicqvhh
FTSWPDHGVPEYATSILQFHRRIKNEYKPTKGPMLVHCSAGVGRTGTFMAIDMGLQQAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLES
. | | . |... ... | . . . | | ||. .|. ..| . .|. |. ...||| |.. || . |..
hapwkhlqqppktlpiikmihqflsekqvqnagvcvvslfgcgracsfigalyainqlnngiepniceimknikqqrpggvesfaqyasiyaivfdy
|
|||||||||
DUF3827 | Domain of unknown function (DUF3827) | 820-915 | 2.7e-06 | 14.3 | Pfam-A | 268-367 (684) | alignment | ||
Range on Protein: 820-915
Range on HMM: 268-367/684.0
TSAIAAGIIVPLLLLIIIVIVIIVVVVSKKKKG-K-HEVVYYNTRAKP--AALEAVSYSVDHVGQYEEVKLETRCGPPPPPAPFKTATPPVIEEFPSNKT
| .|..||.|. ..|.|.. .. |.|. | | . |.|. . . . |.|| .. . | | |.. |.|.| | |..|
nlWiivgvvvPvlvvvviiiilyakLCRkdkldFkpDtvsnlqqRqklqapsvkGFDfAkqHlGqhskDdilviqepaplppskkealpiedaevptpks
|
|||||||||
subfamily_eak_pd | Subfamily eak | 1223-1300 | 2.8e-06 | 21.0 | In-house | 234-312 (332) | alignment | ||
Range on Protein: 1223-1300
Range on HMM: 234-312/332.0
KPTKGPMlVHCSAGVGRTGTFMAIDMGLQ--QAEKEGGIDIISIINKMRQQRMKMVQTADQYIFVNDAVLESVTCGNTQV
|. |. . .. | |.|.|. ||. .. .. |. . .| |....|.. | .| |. |. ..||. . | ..
ppsfapi.iqsarGsaraGvfvvidllirlidnkkknlysvedlilkvkskrihsvlvalqhsfiyeivldyllrrnnrl
|
|||||||||
subfamily_Sponge-PTP3_pd | Subfamily Sponge-PTP3 | 1346-1394 | 3.9e-06 | 21.0 | In-house | 45-94 (95) | alignment | ||
Range on Protein: 1346-1394
Range on HMM: 45-94/95.0
ASQNNDKNRSTQFLPRDNYRVPLKGE-HPDYINAVFINGYKEKKAFIIAE
. | ||| . .| | || | |||||.|..|| |...| |.
seanipknrflnifpydatrvvlttkrdsdyinacfvdgyarkncyiaaq
|
|||||||||
PTEN_1 | 1193-1243 | 4.2e-06 | 21.7 | In-house | 96-147 (196) | alignment | |||
Range on Protein: 1193-1243
Range on HMM: 96-147/196.0
QYHFTSWPDHGVPEYAtSILQFHRRIKNEYK--PTKGPMLVHCSAGVGRTGTF
.|. ...|||.| . ... . ..... .. | .. |||| ||.||.||
eylhfpieDhgapsls.elfdicksfiewllsdpngnvVlVHCkaGlgRsGtv
|
|||||||||
DUF3377 | Domain of unknown function (DUF3377) | 822-859 | 5.6e-06 | 16.0 | Pfam-A | 29-66 (74) | alignment | ||
Range on Protein: 822-859
Range on HMM: 29-66/74.0
AIAAGIIVPLLLLIIIVIVIIVVVVSKKKKGKHEVVYY
|. ...||.|.. |.......| |.| ...|.
vnavaVviPlvLalCiLvlvytivqfkrkgtprrllyc
|
|||||||||
fn3 | Fibronectin type III domain | 282-353 | 7.5e-06 | 19.2 | Pfam-A | 2-77 (85) | alignment | ||
Range on Protein: 282-353
Range on HMM: 2-77/85.0
TPTGLTATRLstGLAQVRLSWSTV----SGATGYEVYYQLS-SNT-PVSVSTTSYTTINILAALSQGSTYTFYVVSYG
|..|... . ...|||| . ||||| |. . .. ........ || .| | |..|.| | ..
aPenlsvsev..tstsltlsWsppkdgggpitgYeveyrekgggeewkeftvprtttsvtltgLkpgteYefrVqavn
|
|||||||||
DUF4448 | Protein of unknown function (DUF4448) | 754-850 | 8.7e-06 | 14.0 | Pfam-A | 104-185 (189) | alignment | ||
Range on Protein: 754-850
Range on HMM: 104-185/189.0
VTLTPTIVSSTSMV-S-TVmqtstviqastliQTSTVMQASTSHTSGTPVTTSAPSSNPTessA---GgsstSAIAAGIIVPLLLLIIIVIVIIVVVVSK
.||.|..|.... .. . .||. .|... .. . .|.... . . ...|. |..|. .......|...... .
itlqpdavpdneefaedsl.............kGptVsltskkdlkkkeksekasnnkse...eegsd....ekyalaialPvvvvvaalgvllfllinr
KK
||
kk
|