subfamily_Sponge-PTP4_pd |
Subfamily Sponge-PTP4 |
67-310 |
1.5e-175 |
575.5 |
In-house |
1-244 (244) |
alignment |
Range on Protein: 67-310
Range on HMM: 1-244/244.0
ALEYEVSRLQDEEVAKEEFVGLSDHTREFLQTNAVLSANATKNRYINILPFDETRVILSSSKKEGSDYINANYIQGSQNIIRPDPSVMKDAFNPNNSWKN
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
aleyevsrlqdeevakeefvglsdhtreflqtnavlsanatknryinilpfdetrvilssskkegsdyinanyiqgsqniirpdpsvmkdafnpnnswkn
REGAGLPFDFNRVPLSKGSMGNTYINASFVGCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEEDEYWPDSEPLEWYEEDITVTLTDRDE
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regaglpfdfnrvplskgsmgntyinasfvgclgrtaeyiltqhpladtsmdfwkmmlerhvnvlvvlgsveeedeywpdseplewyeeditvtltdrde
FKNIKASNLEIESDMNESHQALTMFQISNWPSDGTTPNDHFIMV
||||||||||||||||||||||||||||||||||||||||||||
fknikasnleiesdmneshqaltmfqisnwpsdgttpndhfimv
|
subfamily_Sponge-PTP-4_pd |
Subfamily Sponge-PTP-4 |
170-305 |
1.5e-81 |
265.2 |
In-house |
1-130 (130) |
alignment |
Range on Protein: 170-305
Range on HMM: 1-130/130.0
AGLPFDFNRVPlskgsmGNTYINASFVGCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEEDEYWPDSEPLEWYEEDITVTLTDRDEFKN
|.|.|...|.. |||||||||||.|||||||.||||||||||||||||||||.||||||||||||||||||||||||||||||.|||||||||||
aalefevsrlq......gntyinasfvGllgrtaeylltqhpladtsmdfwkmmleryvnvlvvlgsveeedeywpdsePlewyeediivtltdrdefkn
IKASNLEIESDMNESHQALTMFQISNWPSDGTTPND
|||||||||||.||||||||||||||||||||||||
ikasnleiesdlneshqaltmfqisnwpsdgttpnd
|
0036941 |
(Phosphotyrosine protein) phosphatases II |
157-303 |
2.1e-33 |
111.3 |
In-house |
34-185 (297) |
alignment |
Range on Protein: 157-303
Range on HMM: 34-185/297.0
AFNPNNSWKNREGAGLPFDFNRVPLskGSMGNTYINASFVGCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEE-----DEYWPDSEPLE
| .|.| ||| ||.|..|| | .. |. |||||.| . ... ..|.||.|| .| |||.|..| .|.|.|.| ...| ..|||. |. .
allpenleknRykdilpydhtRVkl..ddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqnvtvIvmltelvelgrekcaqywpleeges
WYEEDITVTLTDRDE--FKNIKASNLEIESDMNESHQALTMFQISNWPSDGTTP
.. .|.||||.. .. ..... .||.. |. . .|.|.. .|| .|. .
ltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpe
|
0040438 |
(Phosphotyrosine protein) phosphatases II |
149-307 |
3.9e-33 |
110.5 |
In-house |
30-192 (317) |
alignment |
Range on Protein: 149-307
Range on HMM: 30-192/317.0
PDPSVMKDAFNPNNSWKNREGAGLPFDFNRVPLSKGSM--GNTYINASFVGCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEED-----
... .. | |.| ||| ||.|..|| || . ...|||||.| . .. ..|.||.|| .| |||.|. | .|.|.| | . || .
lkldtysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPlpntvedFwrmvweqgvtvivmLteleelgrekca
EYWPDsEPLEWYeEDITVTLTDRDEFKNIKASNLEIESDMNESHQALTMFQISNWPsDGTTPNDHF
.|||. . | .|.||||.. .| ..|. .||.| . .. . .| |. .|| |...| ..
qYwpl.getlty.gdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWp.dhgvppspd
|
0050432 |
(Phosphotyrosine protein) phosphatases II |
157-309 |
5.9e-33 |
109.9 |
In-house |
63-219 (308) |
alignment |
Range on Protein: 157-309
Range on HMM: 63-219/308.0
AFNPNNSWKNREGAGLPFDFNRVPLskgSMGNTYINASFVGCL--GRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEE-----DEYWPDSEP
| |.| ||| ||.| .|| | . |..|||||.| . ... ..|.||.|| .| |||.|. | .|.| |.| . .| ..|||...
allpenkdkNrykdilpydhsRVkl...degsdYInAsyvdgyssklprkfIatqgPlpntvedFwrmvweqnvrvIvmLtklvengrekcaqYwplelg
-LEWYEEDITVTLTDRDEFKNIKASNLEIESDMNESHQALTMFQISNWPsDGTTPNDHFIM
.. ...||||.. ....... .||.. .. .| |. ||| |. .|.. |.
ggsleygkftvtllseevlddytvrtleltnlgdgesrtvthfhytnWp.dhgvPpspeil
|
0051299 |
(Phosphotyrosine protein) phosphatases II |
155-306 |
1.3e-32 |
108.8 |
In-house |
42-201 (288) |
alignment |
Range on Protein: 155-306
Range on HMM: 42-201/288.0
KDAFNPNNSWKNREGAGLPFDFNRVPLSK--GSMGNTYINASFVGCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEE-----DEYWPDs
. | |.| ||| ||.| .|| || |. |..|||||.. . .. ..|.||.|| .| |||.|. | .|.| |.| ...| . |||.
saallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyidgynlkrkfIatqgPlpntvedFWrmvweqnvrvIvmltklvelgrekcaqYwpl.
EPLEWYeEDITVTLTDRDEFKNIKASNLEIESD----MNESHQALTMFQISNWPsDGTTPNDH
. . | .||||||.. ....... .||.. .. .. | |. ||| | .|..
ggslty.gditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwp.dhgvpdsp
|
0047943 |
(Phosphotyrosine protein) phosphatases II |
155-305 |
1.3e-32 |
108.7 |
In-house |
31-185 (273) |
alignment |
Range on Protein: 155-305
Range on HMM: 31-185/273.0
KDAFNPNNSWKNREGAGLPFDFNRVPLskGSMGNTYINASFVGCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEE-----DEYWPDSEP
. | |.| ||| ||.| .|| | |. |. |||||.| . .. ..|.||.|| .| |||.|. | .|.|.|.| ...| . |||...
svallpenkdknrykdilpydhsrvkl..gdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvweqnvrviVmLtelvelgrekcaqYwplegg
L-EWYEEDITVTLTDRDEFKNIKASNLEIESDMNESHQALTMFQISNWPSDGTTPND
... ...||||.. ....... .||... .. | |. .|| .|. |.
elsltygkftvtllseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvppsl
|
0046845 |
(Phosphotyrosine protein) phosphatases II |
156-308 |
9.9e-32 |
105.9 |
In-house |
22-186 (284) |
alignment |
Range on Protein: 156-308
Range on HMM: 22-186/284.0
DAFNPNNSWKNREGAGLPFDFNRVPLSKGSMG---NTYINASFVGCL-----GRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEE-----DE
| |.| ||| ||.| .|| |. . . ..|||||.| . .. ..|.||.|| .| |||.|..| .|.|.|.| . .| .
vallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqnvrvIVmltelvengrekcaq
YWPDSEPLEWYeEDITVTLTDRDEFKNIKASNLEIESDM-NESHQALTMFQISNWPsDGTTPNDHFI
|||... .| .|.||||.......... .||.. .. . .| |.. .|| | .| . .
Ywplegevlty.gdftvtllseevkddytvrtleltnlgytgesrtvthfhytswp.dhgvppsped
|
DSPc_SM00195 |
|
154-305 |
1.4e-31 |
105.2 |
In-house |
18-179 (263) |
alignment |
Range on Protein: 154-305
Range on HMM: 18-179/263.0
MKDAFNPNNSWKNREGAGLPFDFNRVPLSKGS--MGNTYINASFVGCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEE-----DEYWPD
...| ..|. ||| ||.| .|| |.| |..||||... . .. .||.||.|| .| |||.|..|..|.. |.| . ||. |.|||.
tteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengkekcdrywpe
SEPLEWYEEDITVTLTDRDEFK-NIKASNLEIESDMNESHQALTMFQISNWPSDGTT--PND
.. .. ..|.|.|.. .. | .|. .||.. . .| .. .| .|. ||| |. ...
esggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstks
|
PTPc_SM00194 |
|
154-305 |
1.4e-31 |
105.2 |
In-house |
18-179 (263) |
alignment |
Range on Protein: 154-305
Range on HMM: 18-179/263.0
MKDAFNPNNSWKNREGAGLPFDFNRVPLSKGS--MGNTYINASFVGCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEE-----DEYWPD
...| ..|. ||| ||.| .|| |.| |..||||... . .. .||.||.|| .| |||.|..|..|.. |.| . ||. |.|||.
tteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengkekcdrywpe
SEPLEWYEEDITVTLTDRDEFK-NIKASNLEIESDMNESHQALTMFQISNWPSDGTT--PND
.. .. ..|.|.|.. .. | .|. .||.. . .| .. .| .|. ||| |. ...
esggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstks
|
0039614 |
(Phosphotyrosine protein) phosphatases II |
154-308 |
1.4e-30 |
102.2 |
In-house |
48-204 (297) |
alignment |
Range on Protein: 154-308
Range on HMM: 48-204/297.0
MKDAFNPNNSWKNREGAGLPFDFNRVPLSKGS---MGNTYINASFVGCLGR-TAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEE----DEYWP
.. | |.| ||| ||.|..|| |. ....|||||.| . . | ..|.||.|| .| |||.|. | .|.|.| | . .| ..|||
ysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIatqgPlpetvedFwrmvweqgvtvivmLtklvelgrkcaqywp
DSEPlewYEEDITVTLTDRDEFKNIKASNLEIESdmNESHQALTMFQISNWPsDGTTPNDHFI
... . .|.||||.. .. .... .||.. |. .|.|| .|| |...|... .
eegg...tygdftvtllkvehldgytvrtlevtn..ngesrtvthfqytgwp.dhgvppslel
|
0043336 |
(Phosphotyrosine protein) phosphatases II |
148-308 |
4.8e-30 |
100.4 |
In-house |
31-194 (278) |
alignment |
Range on Protein: 148-308
Range on HMM: 31-194/278.0
RPDPSVMKDAFNPNNSWKNREGAGLPFDFNRVPLSKGS--MGNTYINASFVGCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEED----
. .. .. | |.| ||| ||.|..|| || . ....|||||.| . .. ..|.||.|| .| |||.|. | .|...|.| . .| .
sfkldtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpetvedFwrmvwelgvttivmLtelvelgrvkc
-EYWPdsEPLEWYeEDITVTLTDRDEFKNIKASNLEIESDMNESHQALTMFQISNWPsDGTTPNDHFI
.||| . . | .|.||||.. ....... .||.. . . | .. .|| |...| . .
aqYwp..ggslty.gdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwp.dhgvpeslsl
|
Y_phosphatase |
Protein-tyrosine phosphatase |
163-306 |
5.7e-30 |
99.8 |
Pfam-A |
2-152 (235) |
alignment |
Range on Protein: 163-306
Range on HMM: 2-152/235.0
SWKNREGAGLPFDFNRVPLSKGSMGNTYINASFVGCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEE-----DEYWPDSEPLEWYEEDI
. ||| ||.|..|| |.. . . ||||..| .. ..|.||.|| .| |||.|.....|.|.|.| |.||. ..|||..| . . .||
kkknRykdilpydktrvklkgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesltygdi
TVTLT-DRD-EFKNIKASNLEIESDMNES-HQALTMFQISNWPsDGTTPNDH
.|.|. . . |.. ..||.... .|| .. ...... ||| | ..|..
kvelkekekedekeytlrklelkkkkeesekrevkqlhytnWp.dhgvpesp
|
Y_phosphatase |
Protein-tyrosine phosphatase |
163-306 |
5.7e-30 |
99.8 |
In-house |
2-152 (235) |
alignment |
Range on Protein: 163-306
Range on HMM: 2-152/235.0
SWKNREGAGLPFDFNRVPLSKGSMGNTYINASFVGCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEE-----DEYWPDSEPLEWYEEDI
. ||| ||.|..|| |.. . . ||||..| .. ..|.||.|| .| |||.|.....|.|.|.| |.||. ..|||..| . . .||
kkknRykdilpydktrvklkgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesltygdi
TVTLT-DRD-EFKNIKASNLEIESDMNES-HQALTMFQISNWPsDGTTPNDH
.|.|. . . |.. ..||.... .|| .. ...... ||| | ..|..
kvelkekekedekeytlrklelkkkkeesekrevkqlhytnWp.dhgvpesp
|
subfamily_PTPRD_pd |
Subfamily PTPRD |
153-301 |
5.8e-30 |
99.4 |
In-house |
39-192 (564) |
alignment |
Range on Protein: 153-301
Range on HMM: 39-192/564.0
VMKDAFNPNNSWKNREGAGLPFDFNRVPLS--KGSMGNTYINASFVGCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEEDE-----YWP
.. | .| | ||| ...| .|| || .| | ||||||. . .|| ||.|||.| .|||.|. |..... | | ..||... |||
tweaankpaNkaKNRyanivaYdhsRVvLskvegdegsDYINAsfidgyrkrkayIAtqgPlaetiedFWRmvweqnsstiVmltkleEkgkvkchkYWP
DSEpLEWYeEDITVTLTDRDEFKNIKASNLEIESDMNESHQALTMFQISNWPSDGT
... | | ...||||.. |.... ..... ... . . |. .||. |
ekg.tety.geltVtleeeeeladyeirtfklkkkkssesreVrqFhFtsWPdhgv
|
0045450 |
(Phosphotyrosine protein) phosphatases II |
157-304 |
9.8e-30 |
99.7 |
In-house |
50-213 (307) |
alignment |
Range on Protein: 157-304
Range on HMM: 50-213/307.0
AFNPNNSWKNREGAGLPFDFNRVPLSKGS---MGNTYINASFV--------GCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEED----
| |.| ||| ||.| .|| || . .. |||||.| .. .. ..|.||.|| .| |||.|. | .|.|.| | . .| .
allpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydlkrkfIatqgPlpetvedFwrmlweqgvtvivmltelvelgrekc
-EYWPDSePLEWYEEDITVTLTDRDEFKNIKASNLEIESD-MNESHQALTMFQISNWPSDGTTPN
.||||. |.. ...||||.. .. .... .||.. .. . .| |. .|| .|. |.
aqywPde.geeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpdhgvpps
|
subfamily_Anemone-PTP-2_pd |
Subfamily Anemone-PTP-2 |
157-308 |
2.1e-29 |
97.7 |
In-house |
51-207 (298) |
alignment |
Range on Protein: 157-308
Range on HMM: 51-207/298.0
AFNPNNSWKNREGAGLPFDFNRVPLSK--GSMGNTYINASFVGCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEEDE-----YWPDSEP
| .|.| ||| ...|. || |.| . .||||||. .. .|.||.|| | |||.|. |......|.| ..|| |. ||||..
arkpenkkkNRyadiialdssRvvLekedadeesdYiNAsflhaykgrnafiatqaPltetvedFWrmvteedigtiVmltnleeldktkyhkywPdegk
lEWYeEDITVTLTDRDEFKNIKASNLEIESDMNESHQALTMFQISNWPSDGTTPNDHFI
| | ..|||.| ..|| .. .|.... .|... . ... ..||. |.. | . .
.ety.geitvsllskeefadlivrklkvskkkeekerevrqlhftsWpdkgvpenatsv
|
0040439 |
(Phosphotyrosine protein) phosphatases II |
159-305 |
9e-28 |
93.0 |
In-house |
8-159 (249) |
alignment |
Range on Protein: 159-305
Range on HMM: 8-159/249.0
NPNNSWKNREGAGLPFDFNRVPLS--KGSMGNTYINASFVGCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEE-----DEYWPDSEPLE
|.| ||| ||.|..|| || .| .. |||||.. . .. ..|.||.|| .| |||.|. | ...|.| | | .| ..|||....||
lpenkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywplggsle
WyeEDITVTLTDRDEFKNIKASNLEIESDMNESHQALTMFQISNWPSDGTTPND
. .|.||||.. ....... .||.. . .. . .|. .|| .|. |.
y..gdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwpdhgvppsf
|
0045098 |
(Phosphotyrosine protein) phosphatases II |
145-307 |
1.4e-27 |
92.3 |
In-house |
16-178 (278) |
alignment |
Range on Protein: 145-307
Range on HMM: 16-178/278.0
NIIRPDPSVMKDAFNPNNSWKNREGAGLPFDFNRVPlskgsmgnTYINASFVGCLgrTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEE----
... ..|| . .| ..| .||| ||.|..|| |||||.. . . ..|.||.|| .| |||.|. | ...|.| | ...|
llllgipseitpalylgnldknRykdilpydhsrVk........dYINAsyidgy..pkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrek
-DEYWPDSEPLEWyeEDITVTLTDRDEFKNIKASNLEIESD----MNESHQALTMFQISNWPSDGTTPND---HF
..|||....|.. .|.||||.. ...... |... . .|.... .|| |. ... .|
caqywpeggslty..gdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksf
|
0042113 |
(Phosphotyrosine protein) phosphatases II |
158-308 |
4.2e-27 |
90.6 |
In-house |
5-159 (245) |
alignment |
Range on Protein: 158-308
Range on HMM: 5-159/245.0
FNPNNSWKNREGAGLPFDFNRVPLSKGSMG--NTYINASFVGCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEE-----DEYWPDsePL
|.| ||| ||.|..|| || . ..|||||.|.. .| .|.||.||..| |||.|. | .....| | . || ..|||.
llpenkdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywpl..ge
EWYEEDITVTLTDRDEFKNIKASNLEIESDMNESHQALTMFQISNWPsDGTTPNDHFI
... .|.||||.. . ..... .||.. . . .. . .. .|| |...|... .
sltygdftvtllseehlddytvrtlevtnlgddesrevihyhylpwp.dhgvpdllel
|
subfamily_PTPRG_pd |
Subfamily PTPRG |
155-308 |
2.9e-26 |
86.8 |
In-house |
40-205 (563) |
alignment |
Range on Protein: 155-308
Range on HMM: 40-205/563.0
KDAFNPNNSWKNREGAGLPFDFNRVPLSKGS--MGN-TYINASFVGCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGS-----VEEEDEYWPD
. . .|.| |||. ...| || ||. . .. ||||... .. ..| ||.||.|| |||.|. |..|...|.. ...| |||
ehsqkpenkrKnRylnivaydrsRvklsplpgkkkklDYinAnyidGyqkskafiatqgplkdtfddFWrmiWeqnvaiivmitnlvergrrkcdvYWPk
SEPLEWyeEDITVTLTDRDEFKNIKASNLEIES-DMN-----ESHQALTMFQISNWPSDGTTPNDHFI
|.... . ..|||.... . .| |. .. .... . .. ..|| |. .
desety..galqvtlieeevlalytvrtlviknlklkkkkqcdteklvrqyhytkWPdhgvPehslpv
|
subfamily_Sponge-PTP11_pd |
Subfamily Sponge-PTP11 |
157-310 |
4.5e-26 |
86.4 |
In-house |
41-202 (290) |
alignment |
Range on Protein: 157-310
Range on HMM: 41-202/290.0
AFNPNNSWKNREGAGLPFDFNRVPLSKGSM----GNTYINASFVGCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEEDE-----YWPDS
.. ..|. .|| .. | ||..| . | | ||||... .||.|| |. .| .||||.. ...| ..|.| .. ||.. |||||
gltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgykekkqyiatqgpvsntlvdFWkliwqekvtiivmltniieegkvkCqqYWpds
EPLEwYEEdITVTLTDRDEFKNIKASNLEIESDMN-ESHQALTMFQISNWPSDGTTPNDHFIMV
. . |.| ....|.. ..... .||.... . ...| .| .||.||.|.| .| . |..
dtka.yge.fsikllneetlneyierklevknknsagakqsvtqyqitnwdstgkvtnpqtill
|
subfamily_Urchin-PTPRB-like_pd |
Subfamily Urchin-PTPRB-like |
157-312 |
1.1e-24 |
82.1 |
In-house |
42-200 (288) |
alignment |
Range on Protein: 157-312
Range on HMM: 42-200/288.0
AFNPNNSWKNREGAGLPFDFNRVPLSK--GSMGNTYINASFVGCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSV-EEE----DEYWPDSEP
. ...| ||| ||.|..|| | | |. |||||.. ... .|| || ||||| |||... |.... .| | .. |.. .|||||..
grlavnakknRyrnilpyDekrvklkkleeeagaDYinasyidgekkkkkyiatqgPladtvndfWelvyenktstivmltelveggktkCeeYWPdadk
LEWYEeDITVTLTDRDEFKNIKASNLEIESDMNEshQALTMFQISNWPSDGtTPNDHFIMVEV
. | ..||||.. | ... .|..| ...| .| .| || .| |... ..|.
pknyG.svtvtlveskeledfvlrklllekkkte..leitqyqylaWpdhg.vPeskapllel
|
subfamily_Sponge-PTP10_pd |
Subfamily Sponge-PTP10 |
156-310 |
1.2e-24 |
81.9 |
In-house |
41-197 (287) |
alignment |
Range on Protein: 156-310
Range on HMM: 41-197/287.0
DAFNPNNSWKNREGAGLPFDFNRVPLSkgSMGNTYINASFVGCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEEDE-----YWPDSEPL
. ..| ||| |. | .||.| . ||||.|. ..|... |...| .|||.. .|.|...|.| .|.|| |||... .
hniasqnkdknRltqilvpdnyrvllk..gehpdyinavfidgykekkafiiaesPmfntarnfWkliddrnvtaivmlcqekendeevcyqyWpeeksv
EWyeEDITVTLTDRDEFKNIKASNLEIESDM-NESHQALTMFQISNWPSDGTTPNDHFIMV
. ...|.... .. .||.. .. ....| .. .|| ||.| | .. |..
vl..GeyniellneevnagyierklevknknkagdkqqvkqyqitnWdstgkvtepqtill
|
subfamily_Anemone-PTP-6_pd |
Subfamily Anemone-PTP-6 |
151-309 |
1.3e-24 |
81.8 |
In-house |
35-197 (318) |
alignment |
Range on Protein: 151-309
Range on HMM: 35-197/318.0
PSVMKDAFNPNNSWKNREGAGLPFDFNRVPLS--KGSMGNTYINASFVGCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEE-----DEY
. .. .| | ||| |..| || |. .|..| ||||... |. .|| .| ||..| |||.|. |.. |.|.| .||. . |
tvtslkslepvnkaknryanilaydhtrvkLqmlegeegsDyinanyidGyrrkkayiaaqaPlpetieDfWrmvWeqnsavivmltqeeergkakvhry
WPDSEPLEWyeEDITVTLTDRDEFKNIKASNLEIESDMNESHQALTMFQISNWPSDGTtPNDHFIM
||.... .. ....|.|... |... ..... . .|... ... .|| |. |.. .
WPskgsrsy..gklvvelkeevelsdyvlrefkvtrteeeesrqvrqyhytsWpdegv.pesgasl
|
subfamily_Sponge-PTP-4_pd |
Subfamily Sponge-PTP-4 |
66-149 |
1.9e-24 |
80.4 |
In-house |
1-109 (130) |
alignment |
Range on Protein: 66-149
Range on HMM: 1-109/130.0
TALEYEVSRLQDEEVAKEEFVGLSDHTREFLQTNAVLSANATK------NRYINIL-----------------PFD--ETRVILSSSKKEGSDYINANYI
.|||.||||||........||||...|.|.|.|...|...... .||.|.| |.. |...|...........|.|...
aalefevsrlqgntyinasfvGllgrtaeylltqhpladtsmdfwkmmleryvnvlvvlgsveeedeywpdsePlewyeediivtltdrdefknikasnl
QGSQNIIRP
........
eiesdlnes
|
subfamily_PTPRB_pd |
Subfamily PTPRB |
154-310 |
5.5e-24 |
79.7 |
In-house |
43-202 (293) |
alignment |
Range on Protein: 154-310
Range on HMM: 43-202/293.0
MKDAFNPNNSWKNREGAGLPFDFNRVPL--SKGSMGNTYINASFVGCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEE-----DEYWPD
.| | .. |. ||| ||.| .|| | |.. |. ||||... . . |.| || || .| |||.|..|......|.| . |. .||||.
vkaaelavnraknrytnilpydhsrvkLaalkdesgsDYinanyipgynsprefiatqGPlpetvddfWrmvwekkssiivmltqlvekgkvkCeeYWPa
SEPLEWYeEDITVTLTDRDEFKNIKASNLEIESdmNESHQALTMFQISNWPSDGtTPNDHFIMV
| | ||.|||. .| .. .|.|| ..... .. .. || | |.. ..
deepvly.Gdikvtlvaeeeledwvirelkiek..ekeerkvrqyhftsWpdhg.vPektktll
|
0037934 |
(Phosphotyrosine protein) phosphatases II |
156-308 |
5.5e-24 |
80.5 |
In-house |
4-154 (243) |
alignment |
Range on Protein: 156-308
Range on HMM: 4-154/243.0
DAFNPNNSWKNREGAGLPFDFNRVPLsKGsmgNTYINASFVGCLGRtaeYILTQHPLADTSMD----FWKMMLERHVNVLVVLGSVEEE-----DEYWPd
| |.| .||| ||.|..|| | .| . ||||... ...| .|.||.|| .| | ||.|. | ...|.| | . .| ..|||
iallpenlsknrysdilpydhsrvkl.eg...sdyinanliyvtpr...liatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywp.
S-EplewYEEDITVTLTDRDEFKNIKASNLEIESDM-NESHQALTMFQISNWPsDGTTPNDHFI
. . . .|.||||.. ...... .|..| .. .. . .. .|| |...|... .
gev....tygdftvtllseehlddytvrtlllenldlddltrlvihyhylpwp.dhgvPdsped
|
subfamily_Sponge-PTP8_pd |
Subfamily Sponge-PTP8 |
161-302 |
2.1e-23 |
78.0 |
In-house |
45-194 (305) |
alignment |
Range on Protein: 161-302
Range on HMM: 45-194/305.0
NNSWKNREGAGLPFDFNRVPLSKGSMGN--TYINASFVGCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEEDE-----YWPDSEPLEWY
.| ||| . ..|..|. |.. . . |||||.| | .||..| || .| |||....| .|...| | . |... |||.|. .
ankaknrlkeitlldddriiltekeslddsdyinasyvdgykrkkkyivaqgPlkntvadfWrliveekvstivmltklveggkdkCrqYWpesktekke
EEDITVTLTDRDEFKNIKASNLEIES-DMNESHQALTMFQISNWPSDGTT
....|.|... .... .|.| | .. .... .|. .|| .|
fgefsvelksektasdyieRklkisiededkesrtvlqyqltdWPdhGvp
|
subfamily_Ptp69D_pd |
Subfamily Ptp69D |
159-305 |
4.5e-23 |
76.8 |
In-house |
45-200 (307) |
alignment |
Range on Protein: 159-305
Range on HMM: 45-200/307.0
NPNNSWKNREGAGLPFDFNRVPLSKGSM--GNTYINASFVGCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEEDE-----YWPDSEPLE
. .| ||| . .|| .|| |.| . .||||||. . ..| | |. | |||.|. | .|...|.| ..| .. |||. . .
kkenalknRyedikafDktRvkLkkingkedsdYinasfikgykekkkfiaaqdPveatigDfWRmiaeqevtlivmlsnlteknrkkcakYWpiedevq
wYEeDITVTLTDRDEFKNIKASNLEIESDMN-----ESHQALTMFQISNWPsDGTTPND
|. || |.| . .. .. .|.. . | .. .. .. .|. | . |.
.yg.dilvklvseekhsdyiiReldvskkkeesgevedsrkvvqyhytgWk.DskvPev
|
subfamily_Nvec-PTP-2_pd |
Subfamily Nvec-PTP-2 |
158-301 |
5.6e-23 |
76.4 |
In-house |
5-152 (250) |
alignment |
Range on Protein: 158-301
Range on HMM: 5-152/250.0
FNPNNSWKNREGAGLPFDFNRVPLSKGS--MGNTYINASFVGCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEED----EYWPDSEPlE
.|.| ||| ...| || | | . ||||||. . .| ||.|| .| |||.|.||......|.| ...|.. .||| .. |
kkpqnkeknryadiialdssrvvLekekgdkesdyinasflhgyderkafiatqgPlqatiedfWrmvleeksgtivmLtnLkesektyhqywPveka.e
WYeEDITVTLTDRDEFKNIKASNLEIESDMNESHQALTMFQISNWPSDGT
| |.||.| ...|| ... .| . . ..... . .. .|| |
ky.GdvtvsllskeefadytkrklklskakkaderivrqlhfvvWPdkgv
|
subfamily_PTPN12_pd |
Subfamily PTPN12 |
157-303 |
5e-22 |
73.1 |
In-house |
35-187 (290) |
alignment |
Range on Protein: 157-303
Range on HMM: 35-187/290.0
AFNPNNSWKNREGAGLPFDFNRVPLSKGS--MGNTYINASFVGCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEED-----EYWPDSEP
. ...| ||| ||.|..|| ||| . |. ||||.|. . ||| .| ||..| |||.|. | .|...|.. . | . |||..
gekeenvkknrykDilPydksrvelskieeeegsdYinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCerYWpeege
LEWYEEDITVTLTDRDEFK-NIKASNLEIESDmnESHQALTMFQISNWPSDGTTP
| ....|||.. . .. .. |..| . . .. .. |. .|| |.
eelefgefevtleeekavdddflirtLkveaq..kesrkvyqfhYtaWPDhgvPs
|
subfamily_PTPN23_pd |
Subfamily PTPN23 |
161-301 |
5.9e-22 |
72.8 |
In-house |
42-186 (288) |
alignment |
Range on Protein: 161-301
Range on HMM: 42-186/288.0
NNSWKNREGAGLPFDFNRVPLSkgSMGNTYINASFVGCLGRT-AEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEE-----DEYWPDSEPLEWYE
.| ||| ||.| ||| | . . ||||||| | . ..| || ||. |. |||.|. |....|.|.| | || |.||| ..
lyseknrsrdilPyDhnRvklr..gskDDYinAsfvkdlspgcPdfiatqaPlqstlnDFWlmvyeqkssviVmllskeelgkpkvdrYwPedkgetvkf
EDITVTLTDRDEFKNIKASNLEIESDMNESHQALTMFQISNWPSDGT
.|..||| . | .. .|..| .. . .. |. .||. |
gdlsvtlksvretethvervlkletldadavksvshlqltsWpelGv
|
subfamily_Anemone-PTP-5_pd |
Subfamily Anemone-PTP-5 |
145-309 |
8.5e-22 |
72.6 |
In-house |
31-200 (319) |
alignment |
Range on Protein: 145-309
Range on HMM: 31-200/319.0
NIIRPDPSVMKDAFNPNNSWKNREGAGLPFDFNRVPLS--KGSMGNTYINASFVGCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEED-
.. ... .. | ...|. ||| |..| || || .|. | .||||||. . ..| || ||..| |||.|. |... ..|.| . |.
llkeavndtfdsaskeenkkknryqnilaydrtrvvlseldgvegsdyinasfidgyqerekfiatqaPlentiedfWrmvWeeessivvmltklveklk
----EYWPDSEPLEwYeEDITVTLTDRDEFKNIKASNLEIESDMNES-HQALTMFQISNWPSDGtTPNDHFIM
.|||. .. | | ..||| ...| ... ..|... .| .. || .|| .. |.. .
vklkkywpeenfee.y.GrlivtleeeeeledyiirklklnkkssevetRevkhfqyteWpdhd.vPekatsl
|
subfamily_PTPN6_pd |
Subfamily PTPN6 |
156-308 |
1.4e-21 |
71.8 |
In-house |
48-207 (306) |
alignment |
Range on Protein: 156-308
Range on HMM: 48-207/306.0
DAFNPNNSWKNREGAGLPFDFNRVPL-SKGSMGNTYINASFVG--CLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEE-----DEYWPDS
.. |.| ||| . |||| .|| | ... .|..||||... | ...|| || | .| |||.|... . .|.|.. | ||||.
egakpenkeknryknilPfDhtrvilkepsvpgsdyinanyikkevkgsdksyiatqgclettvsdFWrmvwqensrvivmttkevErgkekCarYWPde
EPLEWyEEDITVTLTDRDEFKNIKASNLEIE-SDMNESHQALTMFQISNWPSDGTtPNDHFI
| | .|.|| .. .. .. . .| .. . ..... . .. .|| |. |.|
eekee.yGkisvtnvseksladYilRelsvskkkkkkeerevfqyhfksWPdhgv.pkdpga
|
subfamily_Urchin-PTP-8_pd |
Subfamily Urchin-PTP-8 |
159-306 |
2.1e-20 |
68.4 |
In-house |
22-169 (284) |
alignment |
Range on Protein: 159-306
Range on HMM: 22-169/284.0
NPNNSWKNREGAGLPFDFNRVPLSK--GSMGNTYINASFVGCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGsVEEEDEYWPDSEPLEWYEED
..| ||| | |.|| |.| | . | . ||||||. | || || || .| |||.|. | .. .|.| . .||| . . .
ldqnkdknrighilafdknvvklerliGeefsdyinasfitGyqrkdkyiatqGPldntladfWrmiweyncstivllt.kdkcsqywplkivikeerfk
ITVTLTDRDEFknIKASNLEIESDMNE-SHQALTMFQISNWPSDGTTPNDH
. |.. . | ..|. | .| . .. | . || |
vkvdsveesee..yvvrdielsedgkekdirkirqfhflgwpdvgvpdyps
|
subfamily_PTPN9_pd |
Subfamily PTPN9 |
158-311 |
2.4e-20 |
67.8 |
In-house |
38-197 (297) |
alignment |
Range on Protein: 158-311
Range on HMM: 38-197/297.0
FNPNNSWKNREGAGLPFDFNRVPLSK--GSMGNTYINASFVGCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEED-----EYWPDSEPL
. |. ||| | .| || |.| . ||||.|| . .| || || |. |||.|. |..| |.|. |.|. .|||..|
klranleknrytdvlcydetrvvlakvdedeasdyinanfvdGykqkkafiatqGplkktvsdfWrmvWeqevlvivmttrvvergrlkcgqyWpleees
EWYEEDITVTLTDRDEFKNIKASNLEIESDMNESHQALTMFQISNWPSDGTtPNDHFIMVE
|..|. . .| .. | . |||. .| .. .| ||. || |. |.. ...
saefgdlsvsnveveeeedykvrvleiknvkteesrkvthfqflsWPdyGv.Pssaaslld
|
subfamily_Urchin-PTPRA_pd |
Subfamily Urchin-PTPRA |
159-305 |
3.2e-20 |
67.7 |
In-house |
58-204 (319) |
alignment |
Range on Protein: 159-305
Range on HMM: 58-204/319.0
NPNNSWKNREGAGLPFDFNRVPLSK--GSMGNTYINASFVGCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGsVEEEDEYWPDSEPLEWYEED
..| ||| . |.|| |.| | . | . ||||||| | || .| || .| |||.|. | .. .|.| . .||| . . .
ldqnkdknriinilafdknvvklerliGeefsdyinasfvtGyqrkdkyiaaqGPldntladfWrmiweyncstivllt.kdkcsqywplkivikeerfk
ITVTLTDRDEFknIKASNLEIESDMNE-SHQALTMFQISNWPSDGTTPND
. |.. . . ..|. | .| . .| | . || |
vkvdsveetae..yvvrdielsedgkekdirkitqfhflGwpdvGvpdyp
|
subfamily_PTPN3_pd |
Subfamily PTPN3 |
153-312 |
9.2e-20 |
65.7 |
In-house |
32-196 (280) |
alignment |
Range on Protein: 153-312
Range on HMM: 32-196/280.0
VMKDAFNPNNSWKNREGAGLPFDFNRVPLSKGSMgnTYINASFVGC----LGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEED-----EY
.. | |.| ||| ||.| || |.... ||||..| | || || |||.|. |||.|. |......|.| .. |. .|
aisaarkpenlsknryrdilpydatrvklkeset..dyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqksslivmlttlverGrvkChqy
WPDSEPLEWYEeDITVTLTDRDEFKNIKASNLEIESDMNESHQALTMFQISNWPsDGTTPNDHFIMVEV
||..| | ...|... .|| |.. .| .. .. .. .. .| .|| | . |.|. ..|.
WPetedeleyg.efsvkcekedetksyvlrelvlkdketkeerkilqlqylaWp.dhgvPddsadflef
|
subfamily_Urchin-PTP-1_pd |
Subfamily Urchin-PTP-1 |
148-302 |
1.5e-19 |
65.0 |
In-house |
30-189 (315) |
alignment |
Range on Protein: 148-302
Range on HMM: 30-189/315.0
RPDPSVMKDAFNPNNSWKNREGAGLPFDFNRVPL--SKGSMGNTYINASFVGCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEEDE---
||.. . | ...| ||| . ||.| .|| | | . |||||.. . || .| || . |||.|.|. .| .|.. .|.|
dPdiyrqrvaretinfkknryknilPldsarvkleviddsPdsdyinasyiksvdddkayiasqgPlkasvddfwrmvlqekvttivmvtkkqegdkikc
--YWPDSEPLEWYEEDITVTLTDRDEFKNIKASNLeIESDMNESHQaLTMFQISNWPSDGTT
|||| . | |.| . . . | .| . . .||.. .| || .|| |.
rqywPdrkadsvefGsikvellsleadtdgvarkl.vtrkseesrt.vtqfqftewPdkGvd
|
subfamily_PTPRA_pd |
Subfamily PTPRA |
157-312 |
1.7e-19 |
64.9 |
In-house |
53-216 (330) |
alignment |
Range on Protein: 157-312
Range on HMM: 53-216/330.0
AFNPNNSWKNREGAGLPFDFNRVPLS--KGSMGNTYINASFVGCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEEDE-----YWPDSEP
| . .| ||| ||.||.|| || .| ||||||. . ..| .| |...| |||.|. |.. .|.| ..| .| ||||
askeenkeknrvvnilPydfsrvilsvkeGveesdyinasfidGykekdkfiaaqGPkeetvedfwrmiweqksativmltelkerkeekcaqywPdeGl
leWYEEDITVTLTDRDEFKNIKASNLEIE--SDMN--ESHQALTMFQISNWPSDGTtPNDHFIMVEV
. .|.|.. | . ... .. .. .|. .... .. | || | | . |...
..vtyGnirvevedetvlvdytvrkflvqqlpdatrekksrlvrqfhftswPdvGv.PfepiGmlkl
|
subfamily_CG7180_pd |
Subfamily CG7180 |
159-304 |
1.6e-18 |
61.4 |
In-house |
39-198 (296) |
alignment |
Range on Protein: 159-304
Range on HMM: 39-198/296.0
NPNNSWKNREGAGLPFDFNRVPLSK--GSMGNTYINASFVGCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEEDE----YWPDSEpLEW
. .| |||. .|.|.||| |.| | . ||||..| . . .||| |. | .| .||... ..... .||| . . . ||| |
rkenreknrdvkvvPyDynRvvLekldGeeksdYinavyvdsflkkkeyivteapkketvdefWrlvydeeisavvvLtktfdfakmypsywpnks.keq
YEeDITVTLTDRDEFKNIKASNLEIESD------MNE----SHQALTMFQISNWPSDGTTPN
| .| | .. ... |.| .. . ... ...||. |... |
yg.eifveiveekqyanlkirtfkltkkivalteqekqvkaetRivklfqlteWeledkvPl
|
subfamily_Choan-PTP-1_pd |
Subfamily Choan-PTP-1 |
156-306 |
1.7e-18 |
61.8 |
In-house |
35-189 (281) |
alignment |
Range on Protein: 156-306
Range on HMM: 35-189/281.0
DAFNPNNSWKNREGAGLPFDFNRVPLSK--GSMGNTYINASFVGCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEE-----DEYWPDSE
.....| ||| .| || ... .. . ||||.|| . .||| || |. .. ..||.|..|..|...|.. |. |||| .
askadenvlknrYsnivaYDatrvkvtpneenkntDYinanfvpgykgekeyiatqgPvPaslvafWqmvweqkvsaivmvtreieagklkChrYWPddn
PlEWYEEDITVTLTDRDEFKNIKASNLEIESDMNESHqALTMFQISNWPSDGTtPNDH
| |.||. | . | .. ....| . .|. .. .. .|| | |..
s.elkygdvtvkstaeeekatyierkfkleresgetr.eveqlaytaWPdhGv.Patt
|
subfamily_PTPRK_pd |
Subfamily PTPRK |
159-304 |
2.3e-18 |
61.1 |
In-house |
40-190 (314) |
alignment |
Range on Protein: 159-304
Range on HMM: 40-190/314.0
NPNNSWKNREGAGLPFDFNRVPLSK--GSMGNTYINASFVGCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEED-----EYWPDSEPLe
. .| ||| | |..| || | | . ||||... |.|..| ||.|| .| |||..... . .|.| . |. .|||.
kdenreknrsgdilaydrsrvflitidgdpssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasivmltelvevgrvkClkyWPedtev.
wYeEDITVTLTDRDEFKNIKASNLEIES--DMNESHQALTMFQISNWPSDgTTPN
| .|| |.| . . ... . . .| | .. . || .||. .|.
.y.gdikvelvetellaelvvrifrveklargqeeirevrqfqflgWpdh.dvPv
|
subfamily_PTPN13_pd |
Subfamily PTPN13 |
159-311 |
2.9e-18 |
61.1 |
In-house |
34-190 (273) |
alignment |
Range on Protein: 159-311
Range on HMM: 34-190/273.0
NPNNSWKNREGAGLPFDFNRVPLSKGSMgntYINASFVGCLG--RTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEED-----EYWPDSEPLE
. .| ||| ||.| ||.|.. . |||||.. . |||..| || .| |||.|. |....|.... . |.. |||.|. .
kkenkdknryrnvlPydetrvklgdegg...yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvkchrywPesknkk
WYEED-ITVTLTDRDEFKNIKASNLEIESDMNESHQALTMFQISNWPsDGTTPNDHFIMVE
.. ..|.| . . .. . ..|... . . .. .. .|| | .|. ...
lkvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwP.dhgvPssaaellq
|
subfamily_PTPN1_pd |
Subfamily PTPN1 |
155-300 |
3.1e-18 |
60.5 |
In-house |
25-176 (290) |
alignment |
Range on Protein: 155-300
Range on HMM: 25-176/290.0
KDAFNPNNSWKNREGAGLPFDFNRVPLSKGSMgnTYINASFVGCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEED-----EYWPDSE-
..| .|.| .|| |.| |. | ... |||||.| .||||| ||..| ||.|. |.. .|.| | |.. .||| |
reaklpenrnlnryrdvspydhsrikleradn..dyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvvekeqikcaqywPqgee
--PLEWYEEDITVTLTDRDEFKNIKASNLEIESDMNESHQALTMFQISNWPSDG
|. . ..|.| ... .. . . ||.| . . .. | || |
ekellledtklkvkliseerksyytvrllelenlktqetreilhfhyttwpdfg
|
subfamily_Choan-PTP-3_pd |
Subfamily Choan-PTP-3 |
151-304 |
4.1e-18 |
60.2 |
In-house |
27-186 (287) |
alignment |
Range on Protein: 151-304
Range on HMM: 27-186/287.0
PSVMKDAFNPNNSWKNREGAGLPFDFNRVPLS-KGSMGNTYINASFVGCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVL-GSVEEED----EYW
. ..| | . . ||| . ||.| .|| || .| .| |||| .| . ..| .| |.| | |||...||... ..... ||| .||
tatfkaaeelaavkknryadvlPiddtrvllsaegelGsdyinanyvasytddeafiaaqgPiaatvrdfwravletrsasvitmtreveearlkcykyw
PDSE-PLEWYeeDITVTLTDRDEFKN-IKASNLE-IESDMNESHqALTMFQISNWPSDGTTPN
|. | |. .|.| |.| . | |. . .|.. . ... .||... .|
PerevPmrvG..GysvvlldydikePeygvralrlidletrear.vvkqldllswPdkvlaPt
|
subfamily_Anemone-PTP-6_pd |
Subfamily Anemone-PTP-6 |
64-144 |
6.3e-18 |
59.9 |
In-house |
3-86 (318) |
alignment |
Range on Protein: 64-144
Range on HMM: 3-86/318.0
ELTALEYEVSRLQDE--EVAKEEFVGLSDHTREFLQTNAVLSANATKNRYINILPFDETRVILSSS-KKEGSDYINANYIQGSQ
.. .|| | ||. . . .||. || ..... ..... ..|..||||.|||..|.||| |. ..|||||||||||.| .
svedleshvrrlresGelllseeyerlsrseetvtslkslepvnkaknryanilaydhtrvkLqmlegeegsDyinanyidGyr
|
subfamily_Urchin-PTP-5_pd |
Subfamily Urchin-PTP-5 |
162-303 |
2.7e-17 |
57.8 |
In-house |
51-194 (297) |
alignment |
Range on Protein: 162-303
Range on HMM: 51-194/297.0
NSWKNREGAGLPFDFNRVPLSKGSM--GNTYINASFVGCLGRtaEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEEDE----YWPDSEPLEwyEE
| |.| ||.|..|| | |.||||| ..| || | .| |||.|.|. .|...|.| .|.|. ||.|. .
nfeksRYkniLPydssRvkLaivnddpdsDyvnasfvkgnkh..rlittqmPmkatvadfWamvldeqvstivmlnddnerdkkcaryWsdkgvtt..fG
DITVTLTDRDEFKNIKASNLEIESDMNESHQALTMFQISNWPSDGTTP
|..|.|. .| . .||.. . . ... . .| .||..
dvsvvllsvsereGfikrelevtkgkakarrvvkqyqfveWPdkaver
|
subfamily_Sponge-PTP5_pd |
Subfamily Sponge-PTP5 |
160-302 |
4.2e-17 |
56.9 |
In-house |
31-178 (283) |
alignment |
Range on Protein: 160-302
Range on HMM: 31-178/283.0
PNNSWKNREGAGLPFDFNRVPLSKGSMgnTYINASFVG---CLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEEDE-----YWPDSEPLE
.| |||. .| | .|| | | .||||.|. . .|| .| || .| .|||||. .... .|.| . |. . ||| .
denkrknrnqeivpadqwrvelksesr..dyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekitaivmltklqedlrikCsqyWPkrGsed
WYEedITVTLTDRDEFKNIKASNLEIESD-MNESHQALTMFQISNWPSDGTT
. | |||| . . .| . . .| |. .|. .| . |
yGe..ftvtlrkettsnsfiikelllrvnssakstlllahyqvidWleygeq
|
subfamily_PTPRD_pd |
Subfamily PTPRD |
62-142 |
5.6e-17 |
56.6 |
In-house |
4-86 (564) |
alignment |
Range on Protein: 62-142
Range on HMM: 4-86/564.0
PVELTALEYEVSRLQ--DEEVAKEEFVGLSDHtREFLQTNAVLSANATKNRYINILPFDETRVILSSSK-KEGSDYINANYIQG
|.. ..|. | .|. .. .||. .. . ..| ..| .|| |||| ||...|..||.||. . .||||||||..|.|
pipvaelkehvaklkansdlkfeeeykkieeg.qqftweaankpaNkaKNRyanivaYdhsRVvLskvegdegsDYINAsfidg
|
subfamily_PTPN5_RR_pd |
Subfamily PTPN5_RR |
160-311 |
8.6e-17 |
56.1 |
In-house |
26-185 (274) |
alignment |
Range on Protein: 160-311
Range on HMM: 26-185/274.0
PNNSWKNREGAGLPFDFNRVPLSKG-SMGN--TYINASFV-GCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEEDE-----YWPDSEPL
. .. ||| . || . || |.. | . .|||| .. | ... |. || ||. | .|||.|. ...|.|.|.| ..|..| |.||.| .
fgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneqkCavyfPdaedy
EWYE--EDITVTLTDRDEFKNIKASNLEIESDMNesHQALTMFQISNWPsDGTTPNDHFIMVE
| | .|. .. .. | .. . .| ... . .. .. . ..|| | .|.| ...
eiserygdveikvekiverndysvrklvlkyler..ersvkhywytdWP.dhksPddantlld
|
subfamily_Urchin-PTP-7_pd |
Subfamily Urchin-PTP-7 |
157-301 |
1e-16 |
55.8 |
In-house |
44-190 (315) |
alignment |
Range on Protein: 157-301
Range on HMM: 44-190/315.0
AFNPNNSWKNREGAGLPFDFNRVP--LSKGSMGNTYINASFVGCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEED----E-YWPDSep
| . .| ||| ...| || | . . |.||.|. . || .| |.. . |||... | .. .|.| .. |.. | ||||
akkienkqknryiniiaydksrvqlpllendphsdyvnanfidGynkkrryiaaqgpnvasvkdfwrlvfeedigkivmltnlvegekrkaekywpdk..
lEWYEEDITVTLTDRDEFKNIKASNLEIESdmNESHQALTMFQISNWPSDGT
. ||||. . . .... | . . .. . . .... || |
.kviyGkitvtrkseevnteytvrtlsvvf..gdnirevvqlhytswpdmgv
|
subfamily_Sponge-PTP1_pd |
Subfamily Sponge-PTP1 |
159-297 |
1.6e-16 |
55.1 |
In-house |
30-167 (267) |
alignment |
Range on Protein: 159-297
Range on HMM: 30-167/267.0
NPNNSWKNREGAGLPFDFNRVPLSKGSmgNTYINASFVGCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEE--DEYWPDSEPLEWYEED
.| .|| .||.| .||.|.. . |||||.| . . .|.|| || | ||.... ...| | |.| | .. .|| .|
aeknqernrlddnlpyddtrvilrtke..eeyinasyvegyktknafivtqdplkntitdfltvihdqkvpvivlltkvftdnirlfwPPkmgqakkyqd
ITVTLTDRDEFKNIKASNLEIESDmNESHQALTMFQISNWP
.|| . | .. . ||.. ||| . .|.. .|
ltvehslekeendyqiitlelkfk.nesahnvtlyyykkwn
|
subfamily_Fungi-PTP1_pd |
Subfamily Fungi-PTP1 |
106-275 |
5.9e-16 |
53.1 |
In-house |
48-177 (350) |
alignment |
Range on Protein: 106-275
Range on HMM: 48-177/350.0
ATKNRYINILPFDETRVILSSSK---------KEGSDYINANYIQGSQNIIRPDPSVmkdafnpnnswknregaglpfdfnrvplskgsmgntyinasfv
.|||| ||||.. .||.| | ...|||||||.. .. .. .|.
faknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdf...........................................
gclgrtaEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEE-----DEYWPDSEplewyEEDITVTLTDR-DEFKNIKASNL
|| || || | ||.|..|. .|.|.. | | | ..||.. . .|||| |... .. .|. | |
.......kYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcyrYWqegs.....ydditvklaskwenimgindssl
|
subfamily_PTPN14_pd |
Subfamily PTPN14 |
153-305 |
1.1e-15 |
52.4 |
In-house |
40-201 (300) |
alignment |
Range on Protein: 153-305
Range on HMM: 40-201/300.0
VMKDAFNPNNSWKNREGAGLPFDFNRVPLSKGSM-GNTYINASFVGC--LGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEE-----DEYW
... | .|.| ||| ||.. ||| || . ||||| . |.. .|| .| || | |||.|. | .|...| | . ||. .|.
llstaklpenaeknrfkdvlPyednrvelsptkenstgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivmlteeeedgkeksfkyf
PDSEP--LEWYEEDITVTLTDRDEFKNIKASNLEIESDMNESHQALTMFQISNWPSDGtTPND
|..| . . || ... . . .. |... . . .. . ..| .|| .| |.|
PkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhg.vPeD
|
subfamily_Choan-PTP-2_pd |
Subfamily Choan-PTP-2 |
166-306 |
1.7e-15 |
51.8 |
In-house |
24-172 (270) |
alignment |
Range on Protein: 166-306
Range on HMM: 24-172/270.0
NREGAGLPFDFNRVPLSKGS--MGNTYINASFV-GCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEED-----EYWPDSEP--LEWYEE
|| || || |.. . .|||| .| | |....|| .. ||. | .||.|..|..|. .|.. .||. ||| . .. .
nRyadiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkekvkledg
DITVTLTDRDEFKNIKASNLEIEsDMNESHQALtMFQISNWPSDGTTPNDH
.|.|. . . . .|..| . |... . |. .|| .| ...
kikvlalseekeegyiltrlrle.ekgeerrlv.HfwyntWpdhgvpreed
|
subfamily_PTPN6_pd |
Subfamily PTPN6 |
81-144 |
2.6e-15 |
51.2 |
In-house |
28-93 (306) |
alignment |
Range on Protein: 81-144
Range on HMM: 28-93/306.0
AKEEFVGL--SDHTREFLQTNAVLSANATKNRYINILPFDETRVILSSSKKEGSDYINANYIQGSQ
.||| | ..... . .... |..|||| ||||||.|||||.... ||||||||||....
feeefeelqqeeakkllsrkegakpenkeknryknilPfDhtrvilkepsvpgsdyinanyikkev
|
subfamily_PTPRN_pd |
Subfamily PTPRN |
149-248 |
3.3e-15 |
50.6 |
In-house |
43-150 (297) |
alignment |
Range on Protein: 149-248
Range on HMM: 43-150/297.0
PDPSVMKDAFNPNNSWKNREGAGLPFDFNRVPLSKGS--MGNTYINASFVG-CLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEE-----E
.||. . | ...| |||. | ||.| .|| |.. . . |||||.. |.. || || |||.| |||.|. |. | |.| | ..|| .
aepstkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplastvadfwqmvweqGvvvivnltrleeegvkqc
DEYWPDSE
..||||
krywpdeG
|
subfamily_Cele-PTP-20_pd |
Subfamily Cele-PTP-20 |
156-304 |
3.4e-15 |
50.5 |
In-house |
49-200 (290) |
alignment |
Range on Protein: 156-304
Range on HMM: 49-200/290.0
DAFNPNN-SWKNREGAGLPFDFNRVPLSKGSMGNtYINASFVGclGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEE-----DEYWPDSEP
. |. | ||| | || |. | |. |. | .| | | .|||| .|.|| .|.|.|.|. .| ..|.| . |. ..|.|. |
kifdkntefkknrykdvvcndktrvilkdGydGd.yvhanyvk..GlkamfiltqGalkdtvidiwrmvlqekvaaivmlceliedGkakceqyypekeG
LEWYEEDITVTLTDRDE-FKNIKASNLEIESDMNESHQALTMFQISNWPsDGTTPN
.|||. . |. .||. | . . . | ..| || | . ..
evltfGeitvlcseeddkdaniikktlsvrdkdsGkehklkhlkikswp.dksval
|
0050432 |
(Phosphotyrosine protein) phosphatases II |
68-143 |
4.6e-15 |
51.2 |
In-house |
31-102 (308) |
alignment |
Range on Protein: 68-143
Range on HMM: 31-102/308.0
LEYEVSRLQDEEVAKEEFVGLSDHTREFLQTNAVLSANATKNRYINILPFDETRVILssskKEGSDYINANYIQGS
| . . .. | .||| | . . . . | | .| .|||| .|||.| .||.| .||||||||.|..|
llkllekaldlglleeefeellsvkplleysvallpenkdkNrykdilpydhsRVkl....degsdYInAsyvdgy
|
0051299 |
(Phosphotyrosine protein) phosphatases II |
75-142 |
5.9e-15 |
50.9 |
In-house |
19-87 (288) |
alignment |
Range on Protein: 75-142
Range on HMM: 19-87/288.0
LQDEEVAKEEFVGLSDHTREFLQTNAVLSANATKNRYINILPFDETRVILSSSKK-EGSDYINANYIQG
. . .||| | . . . .. |.| .| .|||| .|||.| .||.||. .. ||||||||.||.|
angltglleefeellsllpdltlsaallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyidg
|
subfamily_Urchin-PTP-6_pd |
Subfamily Urchin-PTP-6 |
161-305 |
7.7e-15 |
49.0 |
In-house |
42-191 (515) |
alignment |
Range on Protein: 161-305
Range on HMM: 42-191/515.0
NNSWKNREGAGLPFDFNRVPL--SKGSMGNTYINASFVGCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEEDE-----YWPD--SEPLE
| ||| . ||.| .|| | . . . |.|||.. . || .| |. . |||...|. .| .... .|.| |||| .. ..
infkknryknilPydsvrvklevindnPhsdyfnasyipsfdndkayiasqgPnkasvddfWrlvlqenvttiamvtklkegdkikcgkyWPdkpgdsvk
WyeEDITVTLTDRDEFKNIKASNLEIESdmNESHQALTMFQISNWPSDGTTPND
. | | | . . .|.. .. ...| |. .|| |. ..
f..Gsikvelvsleactggikrkltvlk..gddsrtvtqfhfteWPdkGvpkht
|
fn3 |
Fibronectin type III domain |
1415-1495 |
8.8e-15 |
47.8 |
Pfam-A |
2-84 (85) |
alignment |
Range on Protein: 1415-1495
Range on HMM: 2-84/85.0
APTNFRFTEINFTYVQLAWDPPEPQNGIINLYQIDWERGGRGD-SIRSILPDIR-SIRVSGLTGDVTYTFKIKAQTSAGFGNE
||.|....|.. |...| |.||....| | |..... | |. . . .| | ..||. . .|.|...|.. || | |
aPenlsvsevtstsltlsWsppkdgggpitgYeveyrekgggeewkeftvprtttsvtltgLkpgteYefrVqavngagegpe
|
subfamily_Urchin-PTP-4_pd |
Subfamily Urchin-PTP-4 |
149-301 |
1.3e-14 |
48.4 |
In-house |
32-147 (392) |
alignment |
Range on Protein: 149-301
Range on HMM: 32-147/392.0
PDPSVMKDAFNPNNSWKNREGAGLPFDFNRVPL--SKGSMGNTYINASFVGCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEEDeywpd
|| . . | .. | ||| . ||.| .|| | . . |.|||.. .. || .| | | . |||.|... .| .... ..| |
pdiypqtvaqkeinlkknryknilpydsarvkleviddipdsdylnasyipsfdnekayiasqgpnaaslddfwrmvfqenvttiamvtklkegd.....
seplewyeeditvtltdrdefknikasnleiesdMNESHQALTMFQISNWPSDGT
..... . |....|| ..
..................................kgddartvaqfhftewPdkdv
|
subfamily_Sponge-PTP9_pd |
Subfamily Sponge-PTP9 |
163-305 |
1.5e-14 |
48.4 |
In-house |
41-207 (301) |
alignment |
Range on Protein: 163-305
Range on HMM: 41-207/301.0
SWKNREGAGLPFDFNRVPLSKG----SMGNTYINASFVGCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEE-----DEYWPDSEPLEWY
. || ..| ||. |.. .. ..|||||.. .. ..| .| |. | .|||..... .. .|.. .|. .|||.|| . .
kalnrfknitvyddnriilkpkpnldlcqreyinasyidgysekkkfiaaqgpmkktlvdfWrliwqekpvsivmvtnlkegtkskceqywpnseaesee
EEDITVTLTDRDEFKN-----I-----KASN-------LEIESDMneSHQALTMFQISNWPSDGTTPND
. .||||.. . . . ..|| ....||. | . .. .|. .|| || ..
fgpftvtlvneqvyPdfvirqlnvkiqdgsnngyierkfkvksdk..sswdvlqlqvtdWpqdGvvrep
|
subfamily_Anemone-PTP-4_pd |
Subfamily Anemone-PTP-4 |
161-301 |
1.7e-14 |
48.6 |
In-house |
2-148 (237) |
alignment |
Range on Protein: 161-301
Range on HMM: 2-148/237.0
NNSWKNREGAGLPFDFNRVPLSKGSMGNTYINASFVGCL-GRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEED-----EYWPDSEPLEWYE
.| ||| | .| .|| | | ||||... . | .|| .| || . |||.|. . . |.|.| . | . .|||... . |
enkiknrygnivaydhsrvvlkgagsgsdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpstdqpaayg
eDITVTLTDRDEFKNIKASNLEIESDMNESH-QALTMFQISNWPSDGT
.||.|. ..|| . | . .. . . . .|.. || |
.vltvslkkkeefsdytvrslllskrltlkevrlihqyqftswpdrgv
|
subfamily_Urchin-PTP-3_pd |
Subfamily Urchin-PTP-3 |
150-301 |
2.5e-14 |
48.2 |
In-house |
36-193 (325) |
alignment |
Range on Protein: 150-301
Range on HMM: 36-193/325.0
DPSVMKDAFNPNNSWKNREGAGLPFDFNRVPLS-KGSMG-NTYINASFVGCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEEDE----Y
|. .| | |.| ||| ...| .|| | |. . |||||.. . .. .| ||..| |.|...|. . |.||| ...... |
dgiakkvamkpenkaknrfknvvaldksrvvletkkddpssdyinasylrddkkkdvflaaqaPltatindlWrlvldWrcsvvvvlneldlgkdrcavy
WPDSEPLEWYEEDITVTLTDRDEFKNIKASNLEIESDMNESHQALTMFQISNWPSDGT
||. . | | .|. . |.. . ... ||. |. |.
wpkemgksktfGglevklrtieeisdyvhrvldvkqvkkGetrsvkqfqlqswddmGv
|
subfamily_PTPRB_pd |
Subfamily PTPRB |
67-144 |
2.7e-14 |
47.9 |
In-house |
11-91 (293) |
alignment |
Range on Protein: 67-144
Range on HMM: 11-91/293.0
ALEYEVSRLQD--EEVAKEEFVGLSDHTREFLQTNAVLSANATKNRYINILPFDETRVIL-SSSKKEGSDYINANYIQGSQ
.| |.... . .||. |.. .. .. | |..|..|||| ||||.|..|| | . ....||||||||||.| .
kfeehvkkmkadsdlrfseeyeelkavgkdqavkaaelavnraknrytnilpydhsrvkLaalkdesgsDYinanyipgyn
|
0047943 |
(Phosphotyrosine protein) phosphatases II |
73-142 |
3.5e-14 |
48.4 |
In-house |
6-72 (273) |
alignment |
Range on Protein: 73-142
Range on HMM: 6-72/273.0
SRLQDEEVAKEEFVGLSDHTREFLQTNAVLSANATKNRYINILPFDETRVILsssKKEGSDYINANYIQG
.| . . .||| | . . .. . |.| .| .|||| .|||.| .||.| . .|||||||.|..|
ekllgltllleefelllslkplltysvallpenkdknrykdilpydhsrvkl...gdggsdyinAsyvdg
|
DSPc_SM00195 |
|
84-143 |
4.4e-14 |
47.8 |
In-house |
5-65 (263) |
alignment |
Range on Protein: 84-143
Range on HMM: 5-65/263.0
EFVGLSDHTREFLQTNAVLSANATKNRYINILPFDETRVILSSSKK-EGSDYINANYIQGS
|| | . | . |.| ..| .|||| ||||.|.|||.|....| |||||||||||.|.
efekleestspketteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikga
|
PTPc_SM00194 |
|
84-143 |
4.4e-14 |
47.8 |
In-house |
5-65 (263) |
alignment |
Range on Protein: 84-143
Range on HMM: 5-65/263.0
EFVGLSDHTREFLQTNAVLSANATKNRYINILPFDETRVILSSSKK-EGSDYINANYIQGS
|| | . | . |.| ..| .|||| ||||.|.|||.|....| |||||||||||.|.
efekleestspketteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikga
|
0046845 |
(Phosphotyrosine protein) phosphatases II |
91-143 |
5.1e-14 |
47.8 |
In-house |
12-68 (284) |
alignment |
Range on Protein: 91-143
Range on HMM: 12-68/284.0
HTREF--LQTNAVLSANATKNRYINILPFDETRVILSSSKK--EGSDYINANYIQGS
| . . |.| .| .|||| .|||.| .||.|.| .. |.||||||.|..|
ltvklllslsvallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgy
|
subfamily_Urchin-PTPRB-like_pd |
Subfamily Urchin-PTPRB-like |
81-144 |
8.7e-14 |
46.2 |
In-house |
23-87 (288) |
alignment |
Range on Protein: 81-144
Range on HMM: 23-87/288.0
AKEEFVGLSDHTREFLQTNAVLSANATKNRYINILPFDETRVILSS-SKKEGSDYINANYIQGSQ
.||. |. .. .| . |. ||.|||| ||||.||.|| | ...|.|||||.||.|..
fseeynsLaalektksvtagrlavnakknRyrnilpyDekrvklkkleeeagaDYinasyidgek
|
I-set |
Immunoglobulin I-set domain |
600-691 |
1.1e-13 |
42.8 |
Pfam-A |
3-90 (90) |
alignment |
Range on Protein: 600-691
Range on HMM: 3-90/90.0
LTITPTSLSVNHSDTATFTCTVTSLTTPNITWTTTaTAGITSQPNVLASSQGsdmHTSSLVLTGVILDSIGSYTCTATNEGGSIDTTAMLNV
.|...... |. ......|||. .|...|.. ..|. .| . .. ...|... | . |.|||.|||. |. ..| |.|
ftqklkdvevseGesvelectveGepepsvsWakd.gselkssqrvkvtvee...aeytLtIsnvevsDeGkYtckatnsagkaeakaeLkV
|
0045450 |
(Phosphotyrosine protein) phosphatases II |
68-140 |
1.4e-13 |
46.7 |
In-house |
16-92 (307) |
alignment |
Range on Protein: 68-140
Range on HMM: 16-92/307.0
LEYEVSRLQDEEVAKEEFVGLSDHTR--EFLQTNAVLSANATKNRYINILPFDETRVILSSSKK--EGSDYINANYI
|.. . | . . ..|| | . | . . | | .| .|||| .|||.| |||.||| .. |.||||||.|.
llvllllldfltgllkefekllsvtvfllgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyv
|
0039614 |
(Phosphotyrosine protein) phosphatases II |
66-145 |
2e-13 |
46.0 |
In-house |
19-98 (297) |
alignment |
Range on Protein: 66-145
Range on HMM: 19-98/297.0
TALEYEVSRLQDEEVAKEEFVGLSDHTREflQTNAVLSANATKNRYINILPFDETRVILSSSKK--EGSDYINANYIQGSQN
.| . . .. . . ..|| | . . . .. | | .| .||||..|||.| .||.|.. .. ..||||||.|..|
ldlllllekansktllllefeellslkpd..ysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydl
|
0041856 |
(Phosphotyrosine protein) phosphatases II |
162-304 |
2e-13 |
45.8 |
In-house |
1-95 (182) |
alignment |
Range on Protein: 162-304
Range on HMM: 1-95/182.0
NSWKNREGAGLPFDFNRvplskgsmGNTYINASFVGCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGsveeEDEYWPDSEplewyeeditvtl
| ||| ||.|..| ...||||... . .. ..|.||.|| .| ||..|. |......| | |. |||. .
nldknrysdilpydhsr........dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt....eelywpell.............
tdrdefknikasnleiesdmnesHQALTMFQISNWPSDGTTPN
... . .. .|| .|...
.......................erlgiqylylpwpDhgvpdl
|
0036941 |
(Phosphotyrosine protein) phosphatases II |
81-144 |
2.2e-13 |
45.6 |
In-house |
15-75 (297) |
alignment |
Range on Protein: 81-144
Range on HMM: 15-75/297.0
AKEEFVGLSDHTREFLQTNAVLSANATKNRYINILPFDETRVILsssKKEGSDYINANYIQGSQ
..|| | .. . . | | .| .|||| .|||.| |||.| ..||||||||.|..| .
llkefeellpllllgslsvallpenleknRykdilpydhtRVkl...ddegsdYinAsyvdgyd
|
0040438 |
(Phosphotyrosine protein) phosphatases II |
79-144 |
2.9e-13 |
45.2 |
In-house |
18-83 (317) |
alignment |
Range on Protein: 79-144
Range on HMM: 18-83/317.0
EVAKEEFVGLSDHTREfLQTNAVLSANATKNRYINILPFDETRVILSSSKK-EGSDYINANYIQGSQ
. .||| | . . . . | | .| |||| .|||.| .||.||. .. ..||||||.|..| .
talleefedllslkld.tysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpn
|
subfamily_Choan-PTP-3_pd |
Subfamily Choan-PTP-3 |
95-144 |
6.8e-13 |
43.0 |
In-house |
28-77 (287) |
alignment |
Range on Protein: 95-144
Range on HMM: 28-77/287.0
FLQTNAVLSANATKNRYINILPFDETRVILSSSKKEGSDYINANYIQGSQ
.. .| |.. |||| ..||.|.|||.|| . |||||||||. . .
atfkaaeelaavkknryadvlPiddtrvllsaegelGsdyinanyvasyt
|
subfamily_Anemone-PTP-5_pd |
Subfamily Anemone-PTP-5 |
77-144 |
9.5e-13 |
42.9 |
In-house |
21-88 (319) |
alignment |
Range on Protein: 77-144
Range on HMM: 21-88/319.0
DEEVAKEEFVGLSDHTREfLQTNAVLSANATKNRYINILPFDETRVILSSS-KKEGSDYINANYIQGSQ
| ..|| |. . . ..| | .|||| |||..| |||.||. .||||||||..|.| |
getllekefkllkeavnd.tfdsaskeenkkknryqnilaydrtrvvlseldgvegsdyinasfidgyq
|
subfamily_Sponge-PTP6_pd |
Subfamily Sponge-PTP6 |
164-300 |
1e-12 |
42.2 |
In-house |
50-188 (439) |
alignment |
Range on Protein: 164-300
Range on HMM: 50-188/439.0
WKNREGAGLPFDFNRVPL--SKGSMGNTYINASFVGCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEEDEYWPDSEplEWYEEDITVTL
||| .||. || | | |||| .. || || | .|. |||....|... .|.| . | ||| .. | . ||.|
tknrykdvgafdhtrvtlqeipgvphshyinanyikGyyddklyiatqgpkkettddfwrlviekktvtivmltnlvesykywpsda..evcygdiavrv
TDRDEFKNI--KASNLEIESDMNESHQALTMFQISNWPSDG
|. | . .. | | .| ... |. ||
drnielpnyvirgfkvfnerdttekertvlqfhyiawpdkn
|
subfamily_PTPN12_pd |
Subfamily PTPN12 |
94-145 |
1.3e-12 |
42.2 |
In-house |
29-81 (290) |
alignment |
Range on Protein: 94-145
Range on HMM: 29-81/290.0
EFLQTNAVLSANATKNRYINILPFDETRVILSSSKK-EGSDYINANYIQGSQN
.. .... . | .|||| .|||.|..|| || .. |||||||||.|.|...
vysteagekeenvkknrykDilPydksrvelskieeeegsdYinanfikgveg
|
subfamily_Urchin-PTP-5_pd |
Subfamily Urchin-PTP-5 |
62-146 |
1.5e-12 |
42.3 |
In-house |
9-94 (297) |
alignment |
Range on Protein: 62-146
Range on HMM: 9-94/297.0
PVELTALEYEVSRLQDEEVAKEEFVGLsDHTREFLQTNAVLSANATKNRYINILPFDETRVILSSSKKE-GSDYINANYIQGSQN-I
|. |. . | . .. .| .||| | .. . || | | |.|| ||||.| ||.| . .. |||.|| ...| .. .
piplsdfatlvqknrhtdvfseeflcl.peaniqpqtvaekkvnfeksRYkniLPydssRvkLaivnddpdsDyvnasfvkgnkhrl
|
0043336 |
(Phosphotyrosine protein) phosphatases II |
79-144 |
1.7e-12 |
42.8 |
In-house |
20-85 (278) |
alignment |
Range on Protein: 79-144
Range on HMM: 20-85/278.0
EVAKEEFVGLSDHTReFLQTNAVLSANATKNRYINILPFDETRVILSS-SKKEGSDYINANYIQGSQ
. ..|| | . . . .. | | .| .|||| .|||.| .||.||. .. ..||||||.|. | .
tllllefeellsfkl.dtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvdgyn
|
subfamily_Choan-PTP-4_pd |
Subfamily Choan-PTP-4 |
163-301 |
2.1e-12 |
41.5 |
In-house |
34-179 (297) |
alignment |
Range on Protein: 163-301
Range on HMM: 34-179/297.0
SWKNREGAGLPFDFNRVPLSKGSMGNTYINASFVGCLGRTA--EYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEED-----EYWPDSEPLEWYEE
||| | .| .|| | .. .. |||| .| | |||.| || .| |||... |. |.|.|.. ..|. |||...
lrknryrdilatddtrvkllrviterdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrdkcapywpsvvqerlkag
DITVTLT--DRDEFKNIKASNLEIESDmNEShQALTMFQISNWPSDGT
|. | |||.... ..|.. .|| . .. | .|| |
dvvveflsstsdefdrviltelqliyr.ses.rvvrhvqflswpdhGv
|
subfamily_Ptp69D_pd |
Subfamily Ptp69D |
69-145 |
2.5e-12 |
41.5 |
In-house |
12-89 (307) |
alignment |
Range on Protein: 69-145
Range on HMM: 12-89/307.0
EYEVSRLQDEEVAKEEFVGLSDHTREFLQTNAVLSANATKNRYINILPFDETRVILSSS-KKEGSDYINANYIQGSQN
...... . .. ..|. | .. . ... || |||| .| .||.|||.|. || ||||||..|.| ..
alksrkrdtdfglakeyekLeareidkstkvsekkenalknRyedikafDktRvkLkkingkedsdYinasfikgyke
|
subfamily_Fungi-PTP2_pd |
Subfamily Fungi-PTP2 |
106-241 |
2.6e-12 |
40.8 |
In-house |
49-150 (349) |
alignment |
Range on Protein: 106-241
Range on HMM: 49-150/349.0
ATKNRYINILPFDETRVILSSSKKEgSDYINANYIQGSqniirpdpsvmkdafnpnnswknregaglpfdfnrvplskGSMGNTYINASFVG--CLGRTA
.|||| .|||.. .||.| | | | |.| . ... . |||| .. .
faknrykdilPyehsrvklkkslks.skvikastsesd........................................sgklddyinanylkltrisvek
EYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEE-----D
|| || || | ||.|..| |.... | . .|. |
kyiatqaPlPstvddfykvillngvklvlsLnddkelslekcd
|
subfamily_PTPRA_pd |
Subfamily PTPRA |
59-144 |
3.6e-12 |
40.8 |
In-house |
10-98 (330) |
alignment |
Range on Protein: 59-144
Range on HMM: 10-98/330.0
KLSPVELTALEYEVSR--LQDEEVAKEEFVGLSDHTREFLQTNAVLSANATKNRYINILPFDETRVILSSSK-KEGSDYINANYIQGSQ
| |. . || |. . .| . .||| | . . | | |||..||||.| .||||| . .| |||||| .|.| .
kyfplpvekleeeirirsaddnklfreefnalPagpiqatlelaskeenkeknrvvnilPydfsrvilsvkeGveesdyinasfidGyk
|
I-set |
Immunoglobulin I-set domain |
408-499 |
4.1e-12 |
37.7 |
Pfam-A |
3-90 (90) |
alignment |
Range on Protein: 408-499
Range on HMM: 3-90/90.0
ISISPPSPSVEYNNSTTITCQVTSLTTPNITWTTTaTAGITSQPVVLASSQGsdvYTSSLVLTGVTLDSIGSYTCTATNQGGSSNTTAMLNV
... . . |. ..| ...|.|. .|...|.. ..|. | . .. ...|... |. . |.|||.|||. |.....| |.|
ftqklkdvevseGesvelectveGepepsvsWakd.gselkssqrvkvtvee...aeytLtIsnvevsDeGkYtckatnsagkaeakaeLkV
|
subfamily_Anemone-PTP-2_pd |
Subfamily Anemone-PTP-2 |
84-145 |
1.4e-11 |
39.2 |
In-house |
32-97 (298) |
alignment |
Range on Protein: 84-145
Range on HMM: 32-97/298.0
EFVGLSDHTR---EFLQTNAVLSANATKNRYINILPFDETRVILSS-SKKEGSDYINANYIQGSQN
|| |. . |. .. | ..| |||| .|...| .||.|.. ...| |||||| .... ..
efqrlnsvsseieeeekevarkpenkkkNRyadiialdssRvvLekedadeesdYiNAsflhaykg
|
I-set |
Immunoglobulin I-set domain |
702-787 |
1.5e-11 |
35.9 |
Pfam-A |
7-90 (90) |
alignment |
Range on Protein: 702-787
Range on HMM: 7-90/90.0
PPTLEIYYNTTLKLNCTVFSVTTPTINWTTTaNITIPIENIVTMNTGNmYKSVLTIDNVDLNYTGLYTCSSTNQGGTESDVSNVTV
. .|. .....|.||| . .|...|.. . . .. |... . .. |||.||. . .| ||| ||. |... ...|
lkdvevseGesvelectveGepepsvsWakd.gselkssqrvkvtvee.aeytLtIsnvevsDeGkYtckatnsagkaeakaeLkV
|
subfamily_Urchin-PTPRA_pd |
Subfamily Urchin-PTPRA |
97-145 |
1.6e-11 |
39.1 |
In-house |
53-102 (319) |
alignment |
Range on Protein: 97-145
Range on HMM: 53-102/319.0
QTNAVLSANATKNRYINILPFDETRVILSSS-KKEGSDYINANYIQGSQN
|| | | | |||.||||.||...| | .|.|||||| ...| |.
qtfanldqnkdknriinilafdknvvklerliGeefsdyinasfvtGyqr
|
subfamily_Urchin-PTP-8_pd |
Subfamily Urchin-PTP-8 |
97-145 |
2.7e-11 |
38.5 |
In-house |
17-66 (284) |
alignment |
Range on Protein: 97-145
Range on HMM: 17-66/284.0
QTNAVLSANATKNRYINILPFDETRVILSSS-KKEGSDYINANYIQGSQN
|| | | | |||...||.||...| | .|.|||||| .|.| |.
qtfanldqnkdknrighilafdknvvklerliGeefsdyinasfitGyqr
|
subfamily_CG42327_pd |
Subfamily CG42327 |
187-309 |
3e-11 |
37.5 |
In-house |
55-184 (319) |
alignment |
Range on Protein: 187-309
Range on HMM: 55-184/319.0
GNTYINASFV-GCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEED-----EYWPDSEPLEWYE--EDITVTLTDRDEFKNIKASNLEIE
. |..||.| | . || .| .| |.| |||... |. |.| | .. | ||.| .| |. . || ||| .|. .. | | .
kdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlselGikvcaeylPtketldntslyGdilvtlkgrevkdryaistlllk
SDMNESHQALTMFQIsNWPSDGTTPNDHFIM
.| . || . .|. . .. ..
rvdkeesrelthywy.kwleaevPaeeaali
|
subfamily_Choan-PTP-1_pd |
Subfamily Choan-PTP-1 |
79-143 |
3.7e-11 |
37.7 |
In-house |
15-80 (281) |
alignment |
Range on Protein: 79-143
Range on HMM: 15-80/281.0
EVAKEEFVGLSDHTREFLQTNAVLSANATKNRYINILPFDETRVILS-SSKKEGSDYINANYIQGS
. .||. .|.. .. | . .| .||||.|| .| ||| .. ..... .||||||...|
aGfieeyeklaaigvdntataskadenvlknrYsnivaYDatrvkvtpneenkntDYinanfvpgy
|
subfamily_PTPN3_pd |
Subfamily PTPN3 |
95-141 |
6.2e-11 |
36.7 |
In-house |
31-74 (280) |
alignment |
Range on Protein: 95-141
Range on HMM: 31-74/280.0
FLQTNAVLSANATKNRYINILPFDETRVILSSSKKegsDYINANYIQ
..| ...|..|||| .|||.|.|||.|..|.. |||||||..
laisaarkpenlsknryrdilpydatrvklkeset...dyinanyvn
|
subfamily_PTPN5_RR_pd |
Subfamily PTPN5_RR |
96-145 |
1.5e-10 |
35.7 |
In-house |
19-70 (274) |
alignment |
Range on Protein: 96-145
Range on HMM: 19-70/274.0
LQTNAVLSANATKNRYINILPFDETRVILS--SSKKEGSDYINANYIQGSQN
| . .. ..||||| .||| ...||.|. ||..| |.|||||||.| ..
dqeeldvfgsqtknryktilPnensrvllesessededssyinanyikGyde
|
subfamily_PTPN9_pd |
Subfamily PTPN9 |
83-144 |
1.7e-10 |
35.4 |
In-house |
20-82 (297) |
alignment |
Range on Protein: 83-144
Range on HMM: 20-82/297.0
EEFVGLSDHTREFLQTNAVLSANATKNRYINILPFDETRVILSSS-KKEGSDYINANYIQGSQ
.|.. . ... | ... | || .|||| ..| .||||| |.. ..| |||||||...| .
keyaeirnepveGtflasklranleknrytdvlcydetrvvlakvdedeasdyinanfvdGyk
|
subfamily_Cele-PTP-19_pd |
Subfamily Cele-PTP-19 |
191-309 |
1.8e-10 |
35.0 |
In-house |
78-203 (301) |
alignment |
Range on Protein: 191-309
Range on HMM: 78-203/301.0
INASFVGCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEE-----DEYWPDSEPLEWYEEDITVTLTDRDEF--KNIKASNLEIESDMNE
| | .. |.. .| || || .|| ||| |. .|. .|.|| |. .|| | . . . . ........ |.|. .||.| ..
ihanwiptsGhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkisekldigrfkikiknkelilnkkiskrtlevedstgk
-SHQALTMFQISNWPSDGtTPNDHFIM
. ...| .| |.|. | .|. | .
fatrtvthyqysewtdrg.vPkshael
|
subfamily_egg_pd |
Subfamily egg |
153-248 |
2.1e-10 |
34.8 |
In-house |
31-131 (307) |
alignment |
Range on Protein: 153-248
Range on HMM: 31-131/307.0
VMKDAFNPNNSWKNREGAGLPFDFNRVPL--SKGSMGNTYINASFVGCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEED---EYWPDS
.. |.. || | |. |. || | .| . .| | | |.||.| || .| |||.|. . .|. .|.| | | . ||| .
slttaasdnnlekarskrvhckdssrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvddfwrmvfqeevqyivmltsrkeserceyywpka
E
|
e
|
0049772 |
(Phosphotyrosine protein) phosphatases II |
160-304 |
2.1e-10 |
36.3 |
In-house |
44-195 (314) |
alignment |
Range on Protein: 160-304
Range on HMM: 44-195/314.0
PNNSWKNREGAGLPFDfNRVPLSKGSM-GNTYINASFVGCLgrtAEYILTQHPLADTSMDF----------WKMMLERHVNVLVVLG-------------
. | ||| ||.| ||| |.. .. | |||||.| . .| ||.|| | || |.|.|. || .. .
flnrdknryldilpad.nrvilpglpvsgsdyinasyvdgf...lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivmsrdevladelsrL
--------SVEEEDEYwpdSEPLEWYEEDITvtltdrdefknikasnlEIESDMNESHQA-LTMFQIsNWPSdGTTPN
. . .|| ... |.. |. | . .. .. ..| ..| |..|
daAlgKtpllildgng...neptaadlellk.................eelydpelferlgikylri.pvpD.gsapl
|
subfamily_ptpA1_pd |
Subfamily ptpA1 |
82-143 |
2.2e-10 |
34.8 |
In-house |
24-86 (418) |
alignment |
Range on Protein: 82-143
Range on HMM: 24-86/418.0
KEEFVGLSDHTREFLQTNAVLSANATKNRYINILPFDETRVILSS-SKKEGSDYINANYIQGS
|||| | . .. |..|||| |||| . ||| | ||||||||||||.|.
keefrlleesvgpsetsegdkkhntsknrytnilpvnhtrvqlkkiqdkegsdyinanyidga
|
0045098 |
(Phosphotyrosine protein) phosphatases II |
98-143 |
2.4e-10 |
35.7 |
In-house |
26-62 (278) |
alignment |
Range on Protein: 98-143
Range on HMM: 26-62/278.0
TNAVLSANATKNRYINILPFDETRVIlssskkegsDYINANYIQGS
|.|.. |. |||| .|||.| .||. |||||.||.|
tpalylgnldknRykdilpydhsrVk.........dYINAsyidgy
|
subfamily_Urchin-PTP-3_pd |
Subfamily Urchin-PTP-3 |
73-142 |
2.5e-10 |
35.0 |
In-house |
17-86 (325) |
alignment |
Range on Protein: 73-142
Range on HMM: 17-86/325.0
SRLQDEEVAKEEFvGLSDHTREFLQTNAVLSANATKNRYINILPFDETRVILSSSKKEG-SDYINANYIQG
. ||.. || || .. |.. .| |||. |....|..||.| . |... ||||||.|..
kkaqdqdgfahef.gllpsddgiakkvamkpenkaknrfknvvaldksrvvletkkddpssdyinasylrd
|
subfamily_Cele-PTP-6_pd |
Subfamily Cele-PTP-6 |
151-303 |
2.5e-10 |
34.9 |
In-house |
30-193 (307) |
alignment |
Range on Protein: 151-303
Range on HMM: 30-193/307.0
PS-VMKDAFNPNnSWKNREGAGLPFDFNRVPLSKGSMGNTYINASFVGCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEE-----DEYW
| | .||. | . ||| | .|. . . || | ..| . .| .| || .| .|| |... .|. ...| | | ..||
pegvtveafsan.tdknryqdvkcqdkgrivvkfdglasdyihanylgiaikpkkficaqgplentqysfwamaiqekvesvimlckvielakikceqyw
PDSEP--LEWYEEDITVTLTDRDEF------KNIKASNLEIesDMNESHQALTMFQISNWPSDGTTP
| | | . |. |..... . |. ..|.. | . .... .| .||| |. .
pleegqklvfgeapntisvanlgakklapdedlinvttlkv..dwaqksrtiqhlqwenwpdrgvpq
|
subfamily_Cele-PTP-16_pd |
Subfamily Cele-PTP-16 |
151-243 |
3.2e-10 |
34.1 |
In-house |
37-123 (303) |
alignment |
Range on Protein: 151-243
Range on HMM: 37-123/303.0
PSVMKDAFNpNNSWKNREGAGLPFDFNRVPLSKGSmgntYINASFVGcLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEEDEY
||| |. | .| ||| . .| .| || | || ||.. | . |||| ||. |. |||.|..|..|.....| . | |..
psvsknqfv.knmdknrfvdvicldhskvklsdss....yihasyle.ldsskkailtqlplshtaadfwqmiieqkvkcvlllltdseydkl
|
Ig_3 |
Immunoglobulin domain |
411-486 |
3.4e-10 |
32.0 |
Pfam-A |
7-75 (75) |
alignment |
Range on Protein: 411-486
Range on HMM: 7-75/75.0
SPPSPS-VEYNnsTTITCQVTSLT-TPNITWTttatagiTSQPVVLASSQGSDVYTSSLVLTGVTLDSIGSYTCTATN
||.. .. | |.||.... .|.|.|. ..| .| .|.||. . |.|....|| . |.|||.|.|
spsptvtsggn..vtLtCsaeggpppptisWy.......ietppelqgsegssssestLtissvtsedsGtYtCvasN
|
0037934 |
(Phosphotyrosine protein) phosphatases II |
100-148 |
3.6e-10 |
35.3 |
In-house |
5-48 (243) |
alignment |
Range on Protein: 100-148
Range on HMM: 5-48/243.0
AVLSANATKNRYINILPFDETRVILssskkEGSDYINANYIQGSQNIIR
| | .| .|||| .|||.| .||.| |||||||||.|.. ..|.
allpenlsknrysdilpydhsrvkl.....egsdyinanliyvtprlia
|
Ig_2 |
Immunoglobulin domain |
410-501 |
4.4e-10 |
31.5 |
Pfam-A |
4-80 (80) |
alignment |
Range on Protein: 410-501
Range on HMM: 4-80/80.0
ISPPSPSVEYNNSTTITCQVTSLTTPNITWTTTAtAGITSQPVVlassqgsdVYTSSlvltgVTLDSIGSYTCTATNQGGsSNTTAMLNVTV
.|.|...|. . . |.|||... ||...|. . ..... ..... |... |.|||.|.|..| |... ...|||
lsapptvvtegenvtLtCqapgnptpkvqwykdg.eelsqsqna........lfipn.....vsaedsGtYtCrasnseg.skqsnsvevtv
|
0042113 |
(Phosphotyrosine protein) phosphatases II |
101-144 |
4.8e-10 |
34.7 |
In-house |
5-49 (245) |
alignment |
Range on Protein: 101-144
Range on HMM: 5-49/245.0
VLSANATKNRYINILPFDETRVILSSSKKE-GSDYINANYIQGSQ
| .| .|||| .|||.| |||.||. . . .||||||.|. |..
llpenkdknrysdilpydhtrvklspdggdldsdyinasyvdgyr
|
Y_phosphatase |
Protein-tyrosine phosphatase |
105-145 |
4.9e-10 |
34.6 |
Pfam-A |
1-40 (235) |
alignment |
Range on Protein: 105-145
Range on HMM: 1-40/235.0
NATKNRYINILPFDETRVILsSSKKEGSDYINANYIQGSQN
| .|||| .|||.|.||| | ..... ||||||||..| ..
nkkknRykdilpydktrvkl.kgsegpsdYInAnyvkgyke
|
Y_phosphatase |
Protein-tyrosine phosphatase |
105-145 |
4.9e-10 |
34.6 |
In-house |
1-40 (235) |
alignment |
Range on Protein: 105-145
Range on HMM: 1-40/235.0
NATKNRYINILPFDETRVILsSSKKEGSDYINANYIQGSQN
| .|||| .|||.|.||| | ..... ||||||||..| ..
nkkknRykdilpydktrvkl.kgsegpsdYInAnyvkgyke
|
subfamily_PTPRG_pd |
Subfamily PTPRG |
100-144 |
5e-10 |
33.2 |
In-house |
42-88 (563) |
alignment |
Range on Protein: 100-144
Range on HMM: 42-88/563.0
AVLSANATKNRYINILPFDETRVILSSSK-KEGS-DYINANYIQGSQ
. | ||||.||...|..|| ||. |... ||||||||.| |
sqkpenkrKnRylnivaydrsRvklsplpgkkkklDYinAnyidGyq
|
Ig_2 |
Immunoglobulin domain |
512-592 |
5.8e-10 |
31.1 |
Pfam-A |
8-80 (80) |
alignment |
Range on Protein: 512-592
Range on HMM: 8-80/80.0
NVTITYGMNLTLDCTVSsVFLPLTVEWRFGQMVIKtmnytS---AptgplqVSVTSVTGSNAGVYTCVATHDH-GTDSDNVNVIV
....| | |.|| |... . . .| |. . .. . | . . .|. ...|.|||.|. .. .. |. |.| |
ptvvtegenvtLtCqap.gnptpkvqwykdgeels.....qsqna......lfipnvsaedsGtYtCrasnsegskqsnsvevtv
|
0040439 |
(Phosphotyrosine protein) phosphatases II |
100-143 |
9.2e-10 |
34.0 |
In-house |
6-50 (249) |
alignment |
Range on Protein: 100-143
Range on HMM: 6-50/249.0
AVLSANATKNRYINILPFDETRVILSSSKK-EGSDYINANYIQGS
| | .| |||| .|||.| .||.||. .. ..||||||.|| |.
allpenkdknrypdilpydhsrvklsilpglflsdyinAsyidgy
|
subfamily_Urchin-PTP-1_pd |
Subfamily Urchin-PTP-1 |
80-144 |
1.1e-09 |
32.6 |
In-house |
20-84 (315) |
alignment |
Range on Protein: 80-144
Range on HMM: 20-84/315.0
VAKEEFVGLSDHTrEFLQTNAVLSANATKNRYINILPFDETRVIL-SSSKKEGSDYINANYIQGSQ
. ||| | | . |. | . | .|||| ||||.|..||.| .. |||||| ||.. .
lfseefhdlpdPd.iyrqrvaretinfkknryknilPldsarvkleviddsPdsdyinasyiksvd
|
subfamily_Urchin-PTP-6_pd |
Subfamily Urchin-PTP-6 |
82-145 |
1.1e-09 |
32.0 |
In-house |
21-84 (515) |
alignment |
Range on Protein: 82-145
Range on HMM: 21-84/515.0
KEEFVGLSDhTREFLQTNAVLSANATKNRYINILPFDETRVIL-SSSKKEGSDYINANYIQGSQN
||| | . || | | .|||| ||||.| .||.| . |||.|| ||.. .|
seefhdlpg.pniypqtvaqeeinfkknryknilPydsvrvklevindnPhsdyfnasyipsfdn
|
subfamily_Cele-PTP-18_pd |
Subfamily Cele-PTP-18 |
159-308 |
1.1e-09 |
32.5 |
In-house |
45-208 (305) |
alignment |
Range on Protein: 159-308
Range on HMM: 45-208/305.0
NPNNSWKNREGAGLPFDFNRVPLsKGSMGNTYINASFVGCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEE-----DEYWP--DSEPLE
. ... ||| .| ||| | .|. || | .| . .| || || .| ||| | |. .|. . .| . | ||.. | . ||
eaqeagknrykdvgcldnnrvkl.egpwpheyihanyvstptnpkrfictqaplektcadfwymclqdkveaifmlcnllekgakkcleyfaskdkdvle
WYEED--ITVTLTDRDE--F-----KNIKASNLEIESDMnESHQALTMFQISNWPSDGTTPNDHFI
. |.. |.| . . | ..... | || |. . | . .|| | . | |
feekgqkisvkfessvtlkfrkdakakvtetvlviegpg.ekarkvthyhwidwpdrgvpaadlai
|
subfamily_PTPN13_pd |
Subfamily PTPN13 |
77-141 |
1.3e-09 |
32.8 |
In-house |
9-69 (273) |
alignment |
Range on Protein: 77-141
Range on HMM: 9-69/273.0
DEEVAKEEFVGLSDhTREFLQTNAVLS-ANATKNRYINILPFDETRVILSSSKKegsdYINANYIQ
|.. .||| | . . .... . .| .|||| |.||.|||||.|... ||||..|.
dqqqPaeefkelre.lkpldtcevgkkkenkdknryrnvlPydetrvklgdegg....yinaslik
|
subfamily_Nvec-PTP-2_pd |
Subfamily Nvec-PTP-2 |
103-144 |
1.7e-09 |
32.3 |
In-house |
7-49 (250) |
alignment |
Range on Protein: 103-144
Range on HMM: 7-49/250.0
SANATKNRYINILPFDETRVILSSSK-KEGSDYINANYIQGSQ
.| |||| .|...|..||.| ..| . |||||| ...| .
pqnkeknryadiialdssrvvLekekgdkesdyinasflhgyd
|
0051429 |
(Phosphotyrosine protein) phosphatases II |
188-303 |
2e-09 |
33.0 |
In-house |
4-137 (272) |
alignment |
Range on Protein: 188-303
Range on HMM: 4-137/272.0
NTYINASFVGCLGR---TAEYILTQHPLADTSMDFWKMmLERHVNVLVVLGSVEEE-----DEYWP----------DSEPLEWYEEDITVTLTDRDEFKN
..||||..|| .|| ......|| | |||.. | .... | | |.|| | ||| |... . ...|||. . .
sgyiNardvggygrvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseellld
IKASNLEIESD-MNESHQALTMFQISNWPSDGTTP
. .|... .. ..... .|| .|. .
yilrellltlllsagearevmhlhytdwpdhgvpq
|
subfamily_Sponge-PTP3_pd |
Subfamily Sponge-PTP3 |
98-143 |
2.1e-09 |
31.5 |
In-house |
41-84 (95) |
alignment |
Range on Protein: 98-143
Range on HMM: 41-84/95.0
TNAVLSANATKNRYINILPFDETRVILSSskKEGSDYINANYIQGS
| || |||..||.|.| |||.|.. | |||||| ...|
tvgsseanipknrflnifpydatrvvltt..krdsdyinacfvdgy
|
0049772 |
(Phosphotyrosine protein) phosphatases II |
98-148 |
3.1e-09 |
32.5 |
In-house |
39-88 (314) |
alignment |
Range on Protein: 98-148
Range on HMM: 39-88/314.0
TNAVLSANATKNRYINILPFDeTRVILSSSKKEGSDYINANYIQGSQNIIR
. | | .| .||||..|||.| .||||.. .|||||||.|. | .. |.
lvadlflnrdknryldilpad.nrvilpglpvsgsdyinasyvdgflkfIa
|
subfamily_ptpA1_pd |
Subfamily ptpA1 |
157-246 |
4.8e-09 |
30.4 |
In-house |
42-137 (418) |
alignment |
Range on Protein: 157-246
Range on HMM: 42-137/418.0
AFNPNNSWKNREGAGLPFDFNRVPLSK--GSMGNTYINASFVGCLgRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEE-----DEYWPD
. |. ||| || .. || | | |. |||| .. ..| || || .| |||.|. | .. ..|.| |. | |||.
gdkkhntsknrytnilpvnhtrvqlkkiqdkegsdyinanyidga.ypkqfictqgplpntiadfwrmvwenrcriivmlsresencrikcdrywpe
|
Ig_3 |
Immunoglobulin domain |
606-678 |
4.8e-09 |
28.3 |
Pfam-A |
10-75 (75) |
alignment |
Range on Protein: 606-678
Range on HMM: 10-75/75.0
SLSVNH-SdtATFTCTVTSLT-TPNITWTttatagiTSQPNVLASSQGSDMHTSSLVLTGVILDSIGSYTCTATN
. .. . |.||.... .|.|.|. ..|..| .|.||. |.|....| . |.|||.|.|
ptvtsggn..vtLtCsaeggpppptisWy.......ietppelqgsegssssestLtissvtsedsGtYtCvasN
|
I-set |
Immunoglobulin I-set domain |
804-886 |
4.9e-09 |
27.9 |
Pfam-A |
12-89 (90) |
alignment |
Range on Protein: 804-886
Range on HMM: 12-89/90.0
VTYADTLSIMCNVTSLMRPsSIVWYHNDTLISSGAQPNFTATGapntYTSVLVRDNVVLRDNGVYRCQAENMAGIGAANINIS
|. ..... |.|. | |. |..... ..| . ..|... .. |. .|| .|.| |.|.|.| || |.....
vseGesvelectveGepep.svsWakdgselkssqrvkvtvee....aeytLtIsnvevsDeGkYtckatnsagkaeakaeLk
|
I-set |
Immunoglobulin I-set domain |
504-592 |
5.2e-09 |
27.8 |
Pfam-A |
1-90 (90) |
alignment |
Range on Protein: 504-592
Range on HMM: 1-90/90.0
PSVSIPDDNVTITYGMNLTLDCTVSSVfLPLTVEWRFGQMVIKT---MNYTSAPtGPLQVSVTSVTGSNAGVYTCVATHDHGTDSDNVNVIV
|..... ..|... | ...|.|||. . ...|.| .. .|. ...| . . ...|. |..| |||.|| |... .... |
pkftqklkdvevseGesvelectveGe.pepsvsWakdgselkssqrvkvtvee.aeytLtIsnvevsDeGkYtckatnsagkaeakaeLkV
|
subfamily_PTPN14_pd |
Subfamily PTPN14 |
75-141 |
6.7e-09 |
30.1 |
In-house |
20-85 (300) |
alignment |
Range on Protein: 75-141
Range on HMM: 20-85/300.0
LQDEEVAkEEFVGLSDHTREFLQTNAVLSANATKNRYINILPFDETRVILSSSKKEGSDYINANYIQ
|.. .| |. .. . . | . | | || |||. ..||....|| ||..|.. ..|||| |.
leegkvf.teyeripkkredallstaklpenaeknrfkdvlPyednrvelsptkenstgyinassik
|
subfamily_Urchin-PTP-4_pd |
Subfamily Urchin-PTP-4 |
81-145 |
9e-09 |
29.2 |
In-house |
22-86 (392) |
alignment |
Range on Protein: 81-145
Range on HMM: 22-86/392.0
AKEEFVGLSDHTrEFLQTNAVLSANATKNRYINILPFDETRVIL-SSSKKEGSDYINANYIQGSQN
||| | . . || | | |||| ||||.|..||.| |||.|| ||.. .|
ffeefhdlpgpd.iypqtvaqkeinlkknryknilpydsarvkleviddipdsdylnasyipsfdn
|
subfamily_Sponge-PTP10_pd |
Subfamily Sponge-PTP10 |
82-144 |
9e-09 |
29.7 |
In-house |
23-83 (287) |
alignment |
Range on Protein: 82-144
Range on HMM: 23-83/287.0
KEEFVGLSD-HTREFLQTNAVLSANATKNRYINILPFDETRVILSsskKEGSDYINANYIQGSQ
|. |. | . || | .. | | |||. .||. |. ||.| .| ||||| .|.| .
knqftvleqvtqredevthniasqnkdknRltqilvpdnyrvllk...gehpdyinavfidgyk
|
subfamily_eak_pd |
Subfamily eak |
172-307 |
1.2e-08 |
28.8 |
In-house |
61-200 (332) |
alignment |
Range on Protein: 172-307
Range on HMM: 61-200/332.0
LPFDFNRVPLSKGSMG-NTYINASFVGCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLG-----SVEEEDEYWPDSEPLEWYEEDITVTLTDRD
.|.|.. | |. . . ||||| . .|||| . | . ||.|.||.. .| | .|. | |.|| |. . |. .
vpydrylvrltssqlnrlGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledvelkleksdkyfpdktreelkfGildverkefv
EFKNIKASNLEIeSDMNESHQALtMFQISNWPSDGTTPNDHF
. .... .||. | ||.|. | ... | . . |
krniletrllel.skGnethrvl.hykvfGwtettlpkyedf
|
subfamily_Urchin-PTP-7_pd |
Subfamily Urchin-PTP-7 |
102-143 |
1.3e-08 |
29.1 |
In-house |
46-88 (315) |
alignment |
Range on Protein: 102-143
Range on HMM: 46-88/315.0
LSANATKNRYINILPFDETRVIL-SSSKKEGSDYINANYIQGS
. | |||||||...|..|| | ....|||.|||.|.|
kienkqknryiniiaydksrvqlpllendphsdyvnanfidGy
|
Ig_2 |
Immunoglobulin domain |
601-693 |
1.4e-08 |
26.7 |
Pfam-A |
3-80 (80) |
alignment |
Range on Protein: 601-693
Range on HMM: 3-80/80.0
TITPTSLSVNHSDTATFTCTVTSLTTPNITWTTtATAGITSQPNVlassqgsdMHTSSlvltgVILDSIGSYTCTATNEGGSIDTTAMlNVTV
...... .|. ... |.||.... ||...|. .. .....| ..... | .. |.|||.|.|..||. .. . .|||
vlsapptvvtegenvtLtCqapgnptpkvqwyk.dgeelsqsqna........lfipn.....vsaedsGtYtCrasnsegskqsnsv.evtv
|
subfamily_Sponge-PTP-2_pd |
Subfamily Sponge-PTP-2 |
94-301 |
1.5e-08 |
27.8 |
In-house |
16-154 (169) |
alignment |
Range on Protein: 94-301
Range on HMM: 16-154/169.0
EFLQTNAVLSANATKNRYINILPFDETRVILSSS-KKEGSDYINAnyiqgsqniirpdpsvmkdafnpnnswknregaglpfdfnrvplskgsmgntyin
|. . | |..| |||| | ||| | .. |||||||
eynnfmaeltcnetknrpagplapshtrvklqrvmedlgsdyina.......................................................
asfvgclgrtaeyiltqhpladtsmdfwKMMLERHVNVLVVLGSVEEEDEYWPDSEPL---------EWYEEDITVTlTDRDEFKN-----IKASNLEIE
.|. | |.|||| .. ...||. | ||| . . | ||. . . . .. |
............................rmiwetnasvivvlgdtddknnfwpekedyqlhpavilgewytdslyvr.tdkvhantsgveglfevsmvih
SDMNESHQALTMFQISNWPSDGT
| .. . |.... | || .|
sydddvteklsllhystwpqngv
|
subfamily_Anemone-PTP-1_pd |
Subfamily Anemone-PTP-1 |
162-269 |
1.5e-08 |
29.1 |
In-house |
8-120 (239) |
alignment |
Range on Protein: 162-269
Range on HMM: 8-120/239.0
NSWKNREGAGLPFDFNRVPLSKGSMG--NTYINASFVGC-LGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLG-SVEE----EDEYWPDSEPleWY
| ||| . .|..|| | | | . |||||.. | || || .. .| |||.|| . . |.|.| .| .||||| |
nkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdsts..ky
eEDITVTLTDRDEFKN
.. ||| . | .
.cnlrvtlrktevfad
|
subfamily_Nvec-PTP-1_pd |
Subfamily Nvec-PTP-1 |
162-269 |
1.7e-08 |
28.9 |
In-house |
7-119 (239) |
alignment |
Range on Protein: 162-269
Range on HMM: 7-119/239.0
NSWKNREGAGLPFDFNRVPLSKGSMG--NTYINASFVGC-LGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLG-SVEE----EDEYWPDSEPleWY
| ||| . .|..|| | | | . |||||.. | || || .. .| |||.|| . . |.|.| .| .||||| |
nkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdsts..ky
eEDITVTLTDRDEFKN
.. ||| . | .
.cnlrvtlrktevfad
|
I-set |
Immunoglobulin I-set domain |
311-388 |
1.7e-08 |
26.1 |
Pfam-A |
4-80 (90) |
alignment |
Range on Protein: 311-388
Range on HMM: 4-80/90.0
EVTPDDPTVTYGSDVTLTCSHDDTinaANLTIEWTTTASNTDL-SSVAMTSDT-SSTLTLSNVDLSRTGTYTCDVDDDDG
. ...| .|. |..|.|.|. . .....|.. |.. ..| .| . ..|||.|||. | .|.||| . |
tqklkdvevseGesvelectveGe...pepsvsWakdgselkssqrvkvtveeaeytLtIsnvevsDeGkYtckatnsag
|
Ig_3 |
Immunoglobulin domain |
316-381 |
1.7e-08 |
26.6 |
Pfam-A |
9-71 (75) |
alignment |
Range on Protein: 316-381
Range on HMM: 9-71/75.0
DPTVTYGSDVTLTCSHDDTINaaNLTIEWTtTASNTDLSSVAMTSDTSSTLTLSNVDLSRTGTYTC
|||| | |||||| ... . || |. . |... .|...||||.|.|. . .|||||
sptvtsggnvtLtCsaeggpp..pptisWy.ietppelqgsegssssestLtissvtsedsGtYtC
|
subfamily_Choan-PTP-2_pd |
Subfamily Choan-PTP-2 |
104-145 |
1.8e-08 |
28.7 |
In-house |
19-61 (270) |
alignment |
Range on Protein: 104-145
Range on HMM: 19-61/270.0
ANATKNRYINILPFDETRVILSSSKK-EGSDYINANYIQGSQN
... ||| .||| .|||.|.. .. . . ||||||..| ..
rgkklnRyadiLPsPatRvrleeleedsataYinAnyvrGfdg
|
subfamily_Sponge-PTP2_pd |
Subfamily Sponge-PTP2 |
94-301 |
1.9e-08 |
27.3 |
In-house |
15-153 (169) |
alignment |
Range on Protein: 94-301
Range on HMM: 15-153/169.0
EFLQTNAVLSANATKNRYINILPFDETRVILSSS-KKEGSDYINAnyiqgsqniirpdpsvmkdafnpnnswknregaglpfdfnrvplskgsmgntyin
|. . | |..| |||| | ||| | .. |||||||
eynnfmaeltcnetknrpagplapshtrvklqrvmedlgsdyina.......................................................
asfvgclgrtaeyiltqhpladtsmdfwKMMLERHVNVLVVLGSVEEEDEYWPDSEPL---------EWYEEDITVTlTDRDE-----FKNIKASNLEIE
.|. | |.|||| .. ...||. | ||| . . | ||. . . . | |.
............................rmiwetnasvivvlGdtddknnfwpekedyqlhpavilGewytdslyvr.tdkvhpntsgveglfevslvih
SDMNESHQALTMFQISNWPSDGT
| .. . |.... | || .|
sydddvteqlsllhystwpqngv
|
0043147 |
(Phosphotyrosine protein) phosphatases II |
187-307 |
2.2e-08 |
29.5 |
In-house |
4-84 (172) |
alignment |
Range on Protein: 187-307
Range on HMM: 4-84/172.0
GNTYINASFVGCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVeeedeywpdseplewyeeditvtltdrdefknikasnleiESDMNESHQ
|..|||||.. . . ..| || || | |||.|. |......| | . . |. ..
gsdyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltel........................................lydpeller
ALTMFQISNWPSDGTTPNDHF
.. .|| |... ...
lgiqylylpwpDhgvpllell
|
Ig_2 |
Immunoglobulin domain |
314-400 |
2.2e-08 |
26.0 |
Pfam-A |
6-80 (80) |
alignment |
Range on Protein: 314-400
Range on HMM: 6-80/80.0
PDDPTVTYGSDVTLTCSHDdtiNAANLTIEWTTTASNTDlssvamtsD-TSStLTLSNVDLSRTGTYTCDVDDDDGtIEGTDSIVLTV
. ...|| |..|||||. . . .. .. |. . .. .. | ..|| .. ||||| . . | . ..|. .||
apptvvtegenvtLtCqap...gnptpkvqwykdgeels........qsqna.lfipnvsaedsGtYtCrasnseg.skqsnsvevtv
|
Ig_2 |
Immunoglobulin domain |
1111-1189 |
2.4e-08 |
25.9 |
Pfam-A |
8-78 (80) |
alignment |
Range on Protein: 1111-1189
Range on HMM: 8-78/80.0
EenSTAILGDKFMFRCDPDySNPRPHLQISKiltNGTELNlyTGQSKLHSiMNVAFDDAGNYRCVLTNDY-GRTESNFQL
... |... ..| . .|| | .| .| .|.||. ..|..|.. || .|.|.|.|...|. . . . ...
p..tvvtegenvtLtCqap.gnptpkvqwyk...dgeels..qsqnalfi.pnvsaedsGtYtCrasnsegskqsnsvev
|
Ig_2 |
Immunoglobulin domain |
796-879 |
2.7e-08 |
25.7 |
Pfam-A |
4-72 (80) |
alignment |
Range on Protein: 796-879
Range on HMM: 4-72/80.0
ITSSPmKYVTYADTLSIMCNVTsLMRPSSIVWYHNDTLISSGAQPnftatgapntytsVLVrDNVVLRDNGVYRCQAENMAG-IG
....| .|| ... ..| .. . .. ||......|.. ... || . |.|.|.|.| | | .
lsapp.tvvtegenvtLtCqap.gnptpkvqwykdgeelsqsqna.............lfi.pnvsaedsGtYtCrasnsegskq
|
subfamily_Cele-PTP-14_pd |
Subfamily Cele-PTP-14 |
149-253 |
2.8e-08 |
27.7 |
In-house |
40-149 (310) |
alignment |
Range on Protein: 149-253
Range on HMM: 40-149/310.0
PDPSVMKDAFNpNNSWKNREGAGLPFDFNRVPLSK-GSMGNTYINASFVGCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEED-----E
|.|. .|.. .. ||| . | || | | . || | .| . .| .| || | .|||.|... . ...| | ||
qdssltyeayk.kymhknrysdvvcldtsrvklkidksryedyihanyvktnylrstficsqgplqhtiidfwrmifqeraesilllckvgeegrpkcvg
YWPDSEPLEWY
||| | |
ywpslgvtety
|
subfamily_PTPN23_pd |
Subfamily PTPN23 |
97-142 |
3.9e-08 |
27.4 |
In-house |
35-77 (288) |
alignment |
Range on Protein: 97-142
Range on HMM: 35-77/288.0
QTNAVLSANATKNRYINILPFDETRVILSsskKEGSDYINANYIQG
.. |. ...|||. .|||.|..|| | .. ||||| ....
rsiaiaklyseknrsrdilPyDhnRvklr...gskDDYinAsfvkd
|
subfamily_PTPRK_pd |
Subfamily PTPRK |
102-144 |
4.9e-08 |
27.1 |
In-house |
40-83 (314) |
alignment |
Range on Protein: 102-144
Range on HMM: 40-83/314.0
LSANATKNRYINILPFDETRVILSSSKKE-GSDYINANYIQGSQ
| .|||. .||..| .||.| . . . ||||||..| . .
kdenreknrsgdilaydrsrvflitidgdpssdyinaalidsyk
|
Ig_3 |
Immunoglobulin domain |
503-578 |
5e-08 |
25.0 |
Pfam-A |
1-74 (75) |
alignment |
Range on Protein: 503-578
Range on HMM: 1-74/75.0
PPSVSIPDDNVTITYGMnLTLDCTVSSVFLPLTVEWR-FGQMVIKTMNYTSAPTGPLQVSvtSVTGSNAGVYTCVAT
.|..|.. ..... | .|| |.. . . | |. | . ..... ...| . | .| ||| .. |.|||||.
kPvisvspsptvtsggn.vtLtCsaeggpppptisWyietppelqgsegssssestLtis..svtsedsGtYtCvas
|
subfamily_Cele-PTP-17_pd |
Subfamily Cele-PTP-17 |
185-233 |
5.3e-08 |
26.8 |
In-house |
67-115 (347) |
alignment |
Range on Protein: 185-233
Range on HMM: 67-115/347.0
SMGNTYINASFVGCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVV
.|||||| . . ||||||.|| || |||||. .| .|
ddvetyinashikfdnaskeyiltqyplpdtvrdfwkmvsvtkvtqvvt
|
0036282 |
(Phosphotyrosine protein) phosphatases II |
187-305 |
6.9e-08 |
27.9 |
In-house |
1-86 (174) |
alignment |
Range on Protein: 187-305
Range on HMM: 1-86/174.0
GNTYINASFVGCLGRTAEYILTQHPLAdtsmdFWKMMLERHVNVLVVLGSVEEED-----EYWPDseplewyeeditvtltdrdefknikasnleiesDM
|..|||||... .| ..|..|.||| ||.|. | .....| | . .| . |||. ..
gsdyinaspldlsyitprliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe.................................lr
NESHQALTMFQISNWPSDGTTPND
. .. .. .|| .|. . .
edlerlgiqylylpwpDhgvpdls
|
subfamily_Cele-PTP-12_pd |
Subfamily Cele-PTP-12 |
161-241 |
7e-08 |
26.3 |
In-house |
33-114 (332) |
alignment |
Range on Protein: 161-241
Range on HMM: 33-114/332.0
NNSWKNREGAGLPFDFNRVPLSKGSMGNTYINASFVGCLGRTAEYILTQHPLAD-TSMDFWKMMLERHVNVLVVLGSVEEED
|| || ||..|| |. . . |||.| . . ||..| |. | | ||.|. ||. ....|.| ..|..
nnmdmnriphlycfdhsrvelapqdgkddfynaswvdgyskksayifaqapfndhteyvfwrmvserkpsmilvfgdidekq
|
subfamily_Sponge-PTP11_pd |
Subfamily Sponge-PTP11 |
76-145 |
8.8e-08 |
26.3 |
In-house |
17-89 (290) |
alignment |
Range on Protein: 76-145
Range on HMM: 17-89/290.0
QDEEVAKEEFVGLSDHTREFLQTNAVLSANATKNRYINILPFDETRVILS--SSKKE-GSDYINANYIQGSQN
. .| ...| | .|. | .. | | ..||. ||.. |. |..| |..|. .|||| ||.| ..
kgnegfrnqfkmldsgesehtvtvgltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgyke
|
subfamily_Cele-PTP-6_pd |
Subfamily Cele-PTP-6 |
82-144 |
1.1e-07 |
26.2 |
In-house |
19-79 (307) |
alignment |
Range on Protein: 82-144
Range on HMM: 19-79/307.0
KEEFVGLSDHTREFLQTNAvLSANATKNRYINILPFDETRVILSSSkKEGSDYINANYIQGSQ
..|| |...| | ....| .|||. |||| .. | .|... . |||| |||. .
vdefrvlakktpegvtvea.fsantdknryqdvkcqdkgrivvkfd.glasdyihanylgiai
|
subfamily_PTPN1_pd |
Subfamily PTPN1 |
83-141 |
1.2e-07 |
25.7 |
In-house |
10-65 (290) |
alignment |
Range on Protein: 83-141
Range on HMM: 10-65/290.0
EEFVGLSDHTREFLQTNAVLSANATKNRYINILPFDETRVILSSSKKegsDYINANYIQ
| . .......| ...| | .| ..||| .. |.| .|..| .... |||||. ..
eiyldirkeasdfptreaklpenrnlnryrdvspydhsrikleradn...dyinaslve
|
0046846 |
(Phosphotyrosine protein) phosphatases II |
184-307 |
1.4e-07 |
27.0 |
In-house |
8-95 (176) |
alignment |
Range on Protein: 184-307
Range on HMM: 8-95/176.0
GSMGNTYINASFVGClgrtAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEEDEYWPDSEPLEWYEEDItvtltdrdefknikasnleiesdmne
.. .||||... . . .| ||.|| .| .||..|..| .....| | . | . .. . . |.....|
ldldldyinanlilg....srpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgi..........................
shqaltMFQISNWPSDGTTPNDHF
.. .|| |. . ...
......qylhlpwpDhgvpdlell
|
ig |
Immunoglobulin domain |
322-383 |
1.9e-07 |
22.3 |
Pfam-A |
1-64 (64) |
alignment |
Range on Protein: 322-383
Range on HMM: 1-64/64.0
GSDVTLTCSHddTINAANLTIEWTTTASNTDLSSVAMTSDTSST----LTLSNVDLSRTGTYTCDV
||.||||||. . . .. |. . . .|. ....... ||..|| . ||||| |
GssvtLtCsv..ssgppstdvsWykegkgleesqktgvvenrvsaqevLtinnvtkedsGtYtCvv
|
subfamily_Cele-PTP-10_pd |
Subfamily Cele-PTP-10 |
155-240 |
2.2e-07 |
24.8 |
In-house |
43-133 (305) |
alignment |
Range on Protein: 155-240
Range on HMM: 43-133/305.0
KDAFNPNNS-----WKNREGAGLPFDFNRVPLSKGSmGNTYINASFVGCLG-RTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEE
. ||| |.| ||| | . | |.| | || | .||| .| .| || .| .|| |.....|. .|.| |
qvafnanqsadiaitknryqdvpcqdqsavkldkps.psdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkveqivmlcktvel
|
V-set |
Immunoglobulin V-set domain |
310-393 |
3.5e-07 |
21.1 |
Pfam-A |
4-108 (114) |
alignment |
Range on Protein: 310-393
Range on HMM: 4-108/114.0
VEVTPDDPTVTYGSDVTLTCSHDdTiNAANLTIEWTTTASNTDLSSVA--------------------MTSDTS---STLTLSNVDLSRTGTYTCDVDDD
|. .| || | .|||.|. . . .. .| | .... .. ..|..| .||..|. |. .|||||.| |
vsqsprpvtvaeGgsvtLpCfys.s.sensqsiyWykqktgskpeliiryvaetnnskvgesfsgrvtlssngsksdfsLtiqnlrleDsGtYtCavsds
DGTIEGT
.. ..|.
nedvfga
|
subfamily_Cele-PTP-13_pd |
Subfamily Cele-PTP-13 |
149-277 |
5e-07 |
23.7 |
In-house |
23-160 (281) |
alignment |
Range on Protein: 149-277
Range on HMM: 23-160/281.0
PDPSVMKDAFN-PNNSWKNREGAGLPFDFNRVPLSK---GSMGNTYINASFVGCLGRTAEYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEE----
|| . .|| | | ||| .| || | || | .. ||||| | .| |||.|. . .|.| . |
dppsdlctvfnqpvnnkknrylnipcldisrvqlkvkmpnknstdyihanyirspflkrgyiltqgpkketradfwrmiwqenttaivmlcqfletnrek
-DEYWPDSEPLEWYEEDITVTLTDRDEFKNIKASNLEI
||.| . ..|. | | . .. |..
caeyfprnahcclqfdklsvsyedstvnkslvttrlnl
|
ig |
Immunoglobulin domain |
518-577 |
5.6e-07 |
20.8 |
Pfam-A |
1-64 (64) |
alignment |
Range on Protein: 518-577
Range on HMM: 1-64/64.0
GMNLTLDCTVSSVFLPLTVEWRFGQMVIKTMNYTSAPTGPLQ----VSVTSVTGSNAGVYTCVA
|...|| |.||| . .| | ... . .. ..| . . . ...|| ...|.||||.
GssvtLtCsvssgppstdvsWykegkgleesqktgvvenrvsaqevLtinnvtkedsGtYtCvv
|
Ig_3 |
Immunoglobulin domain |
710-774 |
5.8e-07 |
21.6 |
Pfam-A |
17-75 (75) |
alignment |
Range on Protein: 710-774
Range on HMM: 17-75/75.0
NttLKLNCTVFSVT-TPTINWTttaniTIPIENIVTMNTGNMYKSVLTIDNVDLNYTGLYTCSSTN
| ..|.|.... .||| |. . .. . . . . |.||| .|. ...| ||| .|
n..vtLtCsaeggpppptisWy.....ietppelqgsegssssestLtissvtsedsGtYtCvasN
|
subfamily_Sponge-PTP8_pd |
Subfamily Sponge-PTP8 |
78-144 |
7.4e-07 |
23.6 |
In-house |
21-86 (305) |
alignment |
Range on Protein: 78-144
Range on HMM: 21-86/305.0
EEVAKEEFVGLSDHtREFLQTNaVLSANATKNRYINILPFDETRVILSSSKKEG-SDYINANYIQGSQ
.. .... | .. | .. . .||..|||. .| ..|. |.||. ..... ||||||.|..| .
dkgleaqykslyee.eesidvg.kkeankaknrlkeitlldddriiltekeslddsdyinasyvdgyk
|
subfamily_Cele-PTP-20_pd |
Subfamily Cele-PTP-20 |
99-145 |
7.7e-07 |
23.0 |
In-house |
48-94 (290) |
alignment |
Range on Protein: 99-145
Range on HMM: 48-94/290.0
NAVLSANA--TKNRYINILPFDETRVILSSSKKegSDYINANYIQGSQN
.. .|. .|||| .. | |||||. . ||. |||..| .
rkifdkntefkknrykdvvcndktrvilkdGyd..GdyvhanyvkGlka
|
Ig_2 |
Immunoglobulin domain |
700-787 |
8.7e-07 |
20.9 |
Pfam-A |
4-80 (80) |
alignment |
Range on Protein: 700-787
Range on HMM: 4-80/80.0
LTPPTLEIYYNTTLKLNCTVFSVTTPTINWTTTANITIPIENIvtmntgnmyksvLTIDNVDLNYTGLYTCSSTN-QGGTESDVSNVTV
|..| .. .... |.|.. . ||.. |. ... . .|. | | || ... | |||. .| .|.. |. .|||
lsapptvvtegenvtLtCqapgnptpkvqwykdgeelsqsqna............lfipnvsaedsGtYtCrasnsegskqsnsvevtv
|
fn3 |
Fibronectin type III domain |
1197-1279 |
1e-06 |
21.9 |
Pfam-A |
2-85 (85) |
alignment |
Range on Protein: 1197-1279
Range on HMM: 2-85/85.0
QVTGVTVTYLSFFEILFRWNVPSSNFGRDQRYNVEYRLLLAEA-SSSNITGLTDPSYLLTDVALNVNYSVVVSSNNEVGRGPPS
......|. . .. ..|. |... | ...|.|||| . . . . | .|. ||. . .|.. | . |..| ||.|
aPenlsvsevtstsltlsWsppkdgggpitgYeveyrekgggeewkeftvprtttsvtltgLkpgteYefrVqavngagegpeS
|
subfamily_Cele-PTP-15_pd |
Subfamily Cele-PTP-15 |
188-313 |
1.1e-06 |
22.9 |
In-house |
59-193 (285) |
alignment |
Range on Protein: 188-313
Range on HMM: 59-193/285.0
NTYINASFVGCLGRT-AEYILTQHPLADTSMDFWKMMLERHVNVLVVL-----GSVEEEDEYWPDS--EPLEWYEEDITVTLTDRDEFKNIKASNLEIES
|| ||.. |. . || || || .| |||.|. . .. ...| | ||. |.|. | ... . .||.| . .| .
rdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyypeklgevvkfgkyeitlteckeeaiagtilnaltvin
DMNESHQALTMF--QISNWPsDGTTPNDHFIMVEVT
. | . | | |. || | .|.| |.|.
tedasseplymnhvqvpwwp.dqlapedarpmiely
|
ig |
Immunoglobulin domain |
420-484 |
1.5e-06 |
19.5 |
Pfam-A |
1-64 (64) |
alignment |
Range on Protein: 420-484
Range on HMM: 1-64/64.0
NNSTTITCQV-TSLTTPNITWTTTATAGITSQPVVLASSQGSDVYtsSLVLTGVTLDSIGSYTCTA
..|.|.|| | . ....|. . ..||.. . .| . .| .. || . |.|||..
GssvtLtCsvssgppstdvsWykegkgleesqktgvvenrvsaqe..vLtinnvtkedsGtYtCvv
|
subfamily_Anemone-PTP-4_pd |
Subfamily Anemone-PTP-4 |
104-143 |
1.8e-06 |
22.4 |
In-house |
2-40 (237) |
alignment |
Range on Protein: 104-143
Range on HMM: 2-40/237.0
ANATKNRYINILPFDETRVILSSSKkEGSDYINANYIQGS
| |||| || .| .||.| . |||||||.|..|
enkiknrygnivaydhsrvvlkgag.sgsdyinatylkgf
|
subfamily_Choan-PTP-4_pd |
Subfamily Choan-PTP-4 |
105-141 |
1.9e-06 |
21.9 |
In-house |
31-68 (297) |
alignment |
Range on Protein: 105-141
Range on HMM: 31-68/297.0
NA--TKNRYINILPFDETRVILSSSKkEGSDYINANYIQ
|. |||| .|| .|.||| | . ..|||||.|.
nsslrknryrdilatddtrvkllrvi.terdyinadyvv
|
subfamily_Sponge-PTP1_pd |
Subfamily Sponge-PTP1 |
100-144 |
2e-06 |
22.0 |
In-house |
28-69 (267) |
alignment |
Range on Protein: 100-144
Range on HMM: 28-69/267.0
AVLSANATKNRYINILPFDETRVILSSSKKEgsdYINANYIQGSQ
. . |. .||. . ||.|.|||||. ...| |||| |..| .
siaeknqernrlddnlpyddtrvilrtkeee...yinasyvegyk
|
subfamily_PTPRN_pd |
Subfamily PTPRN |
68-141 |
2.1e-06 |
21.7 |
In-house |
18-93 (297) |
alignment |
Range on Protein: 68-141
Range on HMM: 18-93/297.0
LEYEVSRLQDEEVAKEEFVGLSDHTREFLQT-NAVLSANATKNRYINILPFDETRVILSS-SKKEGSDYINANYIQ
|.| |.... ..|. .| .. | . | |..|||. ..||.|..|| |.. ...| |||||| |
lsyledhlknkdrlekewealcayeaepstkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasail
|
subfamily_Urchin-PTP-2_pd |
Subfamily Urchin-PTP-2 |
99-144 |
2.1e-06 |
21.3 |
In-house |
41-87 (440) |
alignment |
Range on Protein: 99-144
Range on HMM: 41-87/440.0
NAVLSANATKNRYINILPFDETRVILSSSKK-EGSDYINANYIQGSQ
| | | |||| ||| .| .||.| | |||||| ||.| .
iaslpnnkvknryrnilaydhsrvmleevkgvpdsdyinasyingie
|
I-set |
Immunoglobulin I-set domain |
1160-1191 |
3.9e-06 |
18.6 |
Pfam-A |
59-90 (90) |
alignment |
Range on Protein: 1160-1191
Range on HMM: 59-90/90.0
SIMNVAFDDAGNYRCVLTNDYGRTESNFQLIV
| || .|.|.|.|. || .|. |....| |
tIsnvevsDeGkYtckatnsagkaeakaeLkV
|
subfamily_Sponge-PTP6_pd |
Subfamily Sponge-PTP6 |
78-143 |
4.4e-06 |
20.4 |
In-house |
19-87 (439) |
alignment |
Range on Protein: 78-143
Range on HMM: 19-87/439.0
EEVAKEEFVGLSDHTREF--LQTNAVLSANATKNRYINILPFDETRVIL-SSSKKEGSDYINANYIQGS
.|. ||.| .. .. . | . . ||||| .. .|| |||.| | |||||||.|
qeifkeifekinstspdyaciaslaaqeydqtknrykdvgafdhtrvtlqeipgvphshyinanyikGy
|
subfamily_CG42327_pd |
Subfamily CG42327 |
97-144 |
5.4e-06 |
20.3 |
In-house |
20-68 (319) |
alignment |
Range on Protein: 97-144
Range on HMM: 20-68/319.0
QTNAVLSANATKNRYINILPFDETRVILSSSK-KEGSDYINANYIQGSQ
....| . |.|.||..|. ||||.| . .. . |..|.|..| .
radevPvtskdksrvinvvPlPetrvvlqrigdddkdeyldasyvrGyd
|
fn3 |
Fibronectin type III domain |
1297-1387 |
6.1e-06 |
19.5 |
Pfam-A |
4-75 (85) |
alignment |
Range on Protein: 1297-1387
Range on HMM: 4-75/85.0
TNLSSSNINNTinpSIQVKWEPLSpeDGSEFLQRYIVRVNVTDLAAsrgsrrrrqtnpvmTTLEYNVSNAESQFDFTDIKPFMSYSIGVNA
.||| |....| |....|.| . ||.. ...| |.. .. . |..|.. .... .|..|| ..|.. | |
enlsvsevtst...sltlsWsppk..dgggpitgYeveyrekggge..............ewkeftvprtttsvtltgLkpgteYefrVqa
|
subfamily_Nvec-PTP-3_pd |
Subfamily Nvec-PTP-3 |
204-306 |
8.8e-06 |
20.0 |
In-house |
5-113 (198) |
alignment |
Range on Protein: 204-306
Range on HMM: 5-113/198.0
EYILTQHPLADTSMDFWKMMLERHVNVLVVLGSVEEEDE-----YWPDSEPLEWYEEDITV---TLTDRDEFkNIKASNLEIESDMNESHQALTMFQISN
|| ||||| .| |||.|. | .|.. . . | ||| .| ..| |.| . .. | | | .. | . .. .|..
ryiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdy.titaliltnnttappstreishyqfts
WPsDGTTPNDH
| . ||||
wk.ekttpnva
|
subfamily_CG7180_pd |
Subfamily CG7180 |
101-142 |
9.6e-06 |
19.4 |
In-house |
38-80 (296) |
alignment |
Range on Protein: 101-142
Range on HMM: 38-80/296.0
VLSANATKNRYINILPFDETRVILSSSK-KEGSDYINANYIQG
. . | |||.....|.| .||.|.. . .| |||||| |...
lrkenreknrdvkvvPyDynRvvLekldGeeksdYinavyvds
|