Gene SYNJ in Amphimedon queenslandica

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family Sac
Subfamily Synaptojanin
Protein sequence
ID Type Fasta BLAST phosphatome Note
AqueP153_AA protein Get Run
AqueP153_AA_179-484 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_Synaptojanin_pd Subfamily Synaptojanin 57-804 0.0 1223.4 In-house 4-753 (754) alignment 
Range on Protein: 57-804
Range on HMM: 4-753/754.0
NTAYALLGVLQV---GQSLSYIVLVTGCNQVGRISNTEVYQITSTVMVPLHSNPSVHEGVVAMGKLLASGQFYFSVSVDERQnggLFSLLSRSQNRGGTT
  ||.|||||..   ...||..||||||..||.||..|...|||| .|.|.|..|... .... ||||||.||||.| |...    ..| ...|.|  ..
vdaygllGvlrlnagdetlsflvlvtgcksvGkisdaeifkitstelvslrseasdedriielkkllasgtfyfsssadsas...rldlslsaqrrkqee

SQ---FCWNRSLYVYLQRFAVNTDRWVTPLMCGSVQIQTVYAGDKQVKACLISRVSCERAGTRFNVRGLNDEGNVANFVETEQVLSIDKAIASFVQVRGL
|.   |.|||||...||||.||.|.|....|||||.|.|||||.||.||.||||.|||||||||||||.|||||||||||||||...|....||||.|| 
sednrffWnrslhlhlqrfgvncddWllkvmcGsveirtvyagakqakaalisrlsceraGtrfnvrGvndeGnvanfveteqvillddkvtsfvqirGs

VPVFWDQPGIQTGTNRIRLSRGFHCSHAAFVRHFESLLSQYGPCLCVDLLGNRDMEPLLTEAYVDHLRnlEEEVPGAAEYVQFDYHGHCRPKHNEALETI
||.||.|||.|.|.....|||||..|.||| ||.|.| ..|| ...|.|||....| .|..|. .||.  ..|.  ....|.|||| .......|.||..
vPlfWeqPGlqvGshkvklsrgfeasaaafdrhleqlkeryGevvivnllGskegeevlskafkkhlk..asehakdvpfvkfdyhqkvkggkkeklekl

LLPMCSRFIDTCSYYLETDGEVVSAQTGVLRVNCLDCLDRSNNSQAMFGQQLLVQQLDGLKLSSKVNVLSRFKQIFERFWMQNGDNISKLYAGTRALGSS
| .....|....|..|....||...|||||||||||||||.|..|...|...| .||. ||||||..|.|||...|...|..|||.|||.||||.|| ..
lkkqlklflesasfflskgkevekeqtGvlrvnClDCldrtnavqtvlglevlekqlealklsskesvvsrfeevfkslWsknGdeiskiyaGtgalegk

SKVSKLRNSARSVQRTIVNNFMDSSKQEAIDLLLL-NGYVGEIGIQTRNLLKPADLLASLPLRKSLTERWQEYTSTEKLRVCVGTWNVNGGKQMRSIALK
.|||||...||||.||| |||.||||||||||||| |.||.|.. ..|.|||...| ||  ..|.|.||.||.|...|||.||||||||||||.||.|||
akvsklkdgarsvartiqnnfldsskqeaidllllgntyveeladkarallkssllrasakilkelvereqelteakklricvgtwnvnggkqlrsvalk

KESMHDWLLDAPVLSGKKSIPPADVYAIGFQELVALTTSNLVSTNSSNRYAWAAELQHVLSRDHEYSLLTAEQLVGVCLYIFVRPHLIPFIRDVGVSAVK
.||..|||||.| |||.... |||.|||||.|||.|..|||||....||..||.|||.|||||..|.|||.||||||||..||||.|.||||||.||.||
nesltdwlldlpelsgaedskpadiyaiGfeelvdlnasnlvsasttnrkewaeelqkvlsrdakyvlltseqlvGvclfvfvrpklvpfirdvavstvk

TGIGGAAGNKGGVAIRLLLHSTSLCFVCSHLAAHQTKIVERNQDFAEIHRKVLFPMNQTISSHDYVFWCGDLNYRIDLPSSIAKDAISKEEWDKLVRHDQ
||.||||||||.||||||||||||||.||||||.|.|. |||.|.|||.||. |||..|..|||||||.||.||||||.....|....|...||||..||
tGlgGaaGnkGavairlllhstslCfiCshlaagqskvkernedyaeiarkiafpmgrtleshdyvfWlGdfnyridlekdevkelvkkkdydklvendq

LTKQKKLGKVFFGFAEGDLTFAPTYKYDQFSDDYDTSEKCRVPAWCDRILWQRKS
|||||| |||| |||||.||||||||||.||||||||||.|||||.||.||.||.
ltkqkkkgkvfkgfaegeltfaPtykydlfsddydtseklrvPaWtdrvlwrrkk
subfamily_INPP5F_pd Subfamily INPP5F 114-806 9.4e-169 554.5 In-house 127-807 (951) alignment 
Range on Protein: 114-806
Range on HMM: 127-807/951.0
VAMGKLLASGQFYFSVSVDERQNGGLFSLLSRSQN---RggtTSQFCWNRSLYVYLQRFAVNTD-RWVTPLMCGSVQIQTVYAGDKQVKACLISRVSCER
  . ||| .|.||.| ..|  ..    .| ..|.         ..| ||. |   |     ..| ...||.. | |......  ...|.  |||| | .|
eelkkllsdgsFYysldfDltntlqkrgleeksestddw...derFfWNkfllkdlinyrdkldkefltpviqGfvetkeisieklkvsltlisrrSrkr

AGTRFNVRGLNDEGNVANFVETEQVLSIDKAIASFVQVRGLVPVFWDQPGIQTGtNRIRLSRGFHCSHAAFVRHFESLLSQYGPCLCVDLLGNRDMEPLL
|||||. || .|.||||||||||..||. | . ||.|.|| |||||.|.| .    .|.. | .. ...|| .||...|..||.   | || ..  |  |
agtrfkrrGidddgnvAnfvEtElilsvekyvlsftqirGSvPvfweqsgkkyk.pkikitrseeetqpaFdehfkeqlkkygkvvivnllsqkssekkl

TEAYVDHLRNLEeevPGAAEYVQFDYHGHCRPKHNEALETILLPMCSRFIDTCSYYLETDGEVVSAQTGVLRVNCLDCLDRSNNSQAMFGQQLLVQQLDG
 .|| ..|..||        ...||.| ... .. |......  .     .   .  . ...|.| |.||.|.|||||||| |  |.. ....| .||  
skaykeqllkle...skdvflikfdfheetsgekfenvsklielikneikevgyfsydvkekviseqkgvfRtnclDcldrtNvvqqaiskavlelqlek

LKLSSKVNVLS--RFKQIFERFWMQNGDNISKLYAGTRALGSS-SKV------SKLRNSARSVQRTIVNNFMDSSKQEAIDLlllngYVGEIGIQT-RNL
|.| .  . .   ...| .. .| .||| ||. |||| || .. ..         | .   ||.|  .|||.|. .|..|||       |..  |   .|
lglfepessiddeellqklkklWadngdaisrqYagtnalkgdltrkgerklaGvlkdgyksvsryylnnfkdkyrqkvidl.....llGklpkqevvel

LKPADLLASLPLrkslTERWQEYTSTEKLRVCVGTWNVNGgkQMrsialKKESMHDWLLDApvlsGKKsiPPADVYAIGFQELVALTTSNLVSTNSSNRY
 .|     .  |     |. ...|.|  . . ||. ||||  .      ||. .  .| .     |.|  . .|.. .| || | ||. .......| . 
idpkkeekeeel....rekeekftetsninllvgsvnvng..ss.....kkadlskllfpi....gek..fkpDlvvlGLqEvvELtaGsiLaaDysksk

AWAAELQHVLS---RDHEYSLLTAEQLVGVCLYIFVRPHLIPFIRDVGVSAVKTGIGGAAGNKGGVAIRLLLHSTSLCFVCSHLAAHQTKIVERNQDFAE
 |   ....|    |.. | .| .|||... | .|||   .  ...|... .|||.|| |||||.||.|.    || ||| ||||| .. . || .|. |
fWEklvedlLnkvsreekYlkLrseqlsslLlllfvredkakkvkevegdtkktGfgGlagnkGavavrfeysatsFcfvnsHlaAGasnveeRrsDyke

IHRKVLFPMNQTISSHDYVFWCGDLNYRIDLPSSIAKDAISKEEWDKLVRHDQLTKQKKLGKVFFGFAEGDLTFAPTYKYDQFSDDYDTSEKCRVPAWCD
|.|.. |. ...|. ||..|| ||||||||||    .  . ..|.||| ..|||||. . |.|| || |  | | ||||||  ...|||||| |.||| |
iarsitFsrskrikdhDsifWlGDlnyRidlpneevRRelldqeidkLleyDqLtkeieaGevFegfkEetlkFrPtYkyDlgtknYDtsekeRtPaWtD

RILWQRKSFL
||... . . 
Riiykgevle
Sac_COG5329 58-806 5.9e-112 366.6 In-house 60-820 (1070) alignment 
Range on Protein: 58-806
Range on HMM: 60-820/1070.0
TAYALLGVLQVgQSLSYIVLVTGCNQV-GRISNTEVYQITSTVMVPLHSNPSVHEGV----VAMG------------KLLASGQFYFSVSVDERQ---NG
. | .||.... . .... ..||  .| ..| . ..| |    ...|  |   .|        .             |||  | ||||   |  .   . 
eiygvlGliel.egslflivitgkskvaqvipgetiykilavdfislnnnkwddeeiesdeasteklrsehpcselkkLlsngsFYfStdfditntLqkr

gLFSLLSRSQNRggTTSQFCWNRSLYVYLQRFAVNTD----------RWVTPLMCGSVQIQTVYAGDKQVKACLISRVSCERAGTRFNVRGLNDEGNVAN
 |.  |. | ..     .|.||. |.  |  .. . .          .. |.. .| ..   .. . |..   ||||.| .||||||. ||..|.|||||
.lkeelelsvdt..adeefmwnsflleelinyrsklsslekqlldnagFlttvIrGFaetvfikvkkktiaLtlISRrSskragtRflarGvDddGnvan

FVETEQVLSIDKAIASFVQVRGLVPVFWDQPGIQTGTNRIRLSRGFHCSHAAFVRHFESLLSQYGPCLCVDLLGNRDMEPLLTEAYVDHLRNLEEEVPga
||||||..   . . ||.|||| .|.|| | . ..   .|. .| .  . .|| .||..| ..||.   |.||..   |  |.|.|  ||...|..    
FVETEqIvyssqycfsFtQvRGSiPiFWeqesnsligpkiqitrsseatqsafdkHFdklfekYGdvhivNLlktKssEieLseryekhlklsekpki..

aEYVQFDYHGHCRPKHNEALETIlLPMCSRFIDTCSYYL--ETDGEVVSAQTGVLRVNCLDCLDRSNNSQAMFGQQLLVQQLDGLKLSSKVNVLsRFKQI
  ...||.| .....  .... . ||.    . .  |.   . .|...| |.||.|.|||||||| |  | . ....| .|.  .| .|. .    | |.
.hlteFdfhketsqdgfddvkkL.lplieqdllefgyfsydvkegkliseQdGVfRtNClDCLDRTNviQqliskrvlleqfrsikvisaidde.dflqk

FERFWMQNGDNISKLYAGTRALGSS-------SKVSKLRNSARSVQRTIVNNFMDSSKQEAIDLLLlngyvGEIGIQTRN-LLKPADLLASLPlrksLTE
..  |  ||| ||..| || || ||       | ...|.    ||.| ..|||.| .||.||||||     |.   |.   |..| .    |     |..
lneLWadnGDaisqiYTGtgalkssftrkgkrsiagalsDatkSvsRmyinnfvDkekQdaidllL.....gklpdqeavelydpineyvnlr....lrk

RWQEYTSTEKLRVCVGTWNVNGgkqmrsiALKKESMHDWLLDapVLSGKksippADVYAIGFQELVALTTSNLVSTNSSNRYAWAAELQHVLSRDHE--Y
...|.|  . . . ..| |.||        .....  ..||.  ||  |     .. .  |...|.  .. .|.. .|...  .  | . .| |. |  .
seseftaaknvsiftltfnsng.......essstkllklllk..vlekk.....isklvvgvvglqkqiwlelillssltksefkeeeeenlvrkyenkl

SLLTAEQLVGVCLYIFVRPHLIPFIRDVGVSAVKTGIGGAAGNKGGVAIRLLLHSTSLCFVCSHLAAHQTKIVERNQDFAEIHRKVLFPMNQTISSHDYV
.    || . .   .|..      |  |..|  ..| ..  |........     .| ..|  .. |..  ..|....   . . . ... ..|......
kkkkleqsssqltalfilfkksadikevvssekaagrktgtgglnankgavkieaeseglvfifvdasaaledenesernskyesitkrvskeipkmikd

FWCGDLNYRIDLPSSIAKDAISKEEWDKLV--RHDQLTKQKKLGKVFFGFAEGDLTFAPTYKYDQFSDDYDTSEKCRVPAWCDRILWQRKSFL
.. ..|...|.|     .... .|. ..      ...|||.  .|||... .   .. ......   ||.||... .......|.| |..  .
hqlilldiainltidydeeevraekekeidrelkkydtkqeltekvfvekvleptevpellekksyeddndtdtedayrklrtrkliqkeekk
subfamily_SAC1_pd Subfamily SAC1 56-486 4.1e-87 283.7 In-house 4-452 (458) alignment 
Range on Protein: 56-486
Range on HMM: 4-452/458.0
INTAYALLGVLQVgQSLSYIVLVTGCNQVGRISNTEVYQITSTVMVPLHSNPSVH-------E--GVVAMGKLLASGQFYFSVSVDERQ-----NGGLFS
... ...||....  | .|....|  ..||||..  .|... . ..|...|.          |   .  . ..| | .||||.  |  .     .    .
vvkiagilGiikL.lsgkylivitkkeevgringkviyrvadveiipvkknslslteeqkkeekeylkllelvlksetfYfsytydltnslqrlekvtsa

LLSRSQNRGGTTSQFCWNRSLYVYLQRfAVNTDRWVTPLMCGSVQIQTVYAGDKQVKACLISRVSCERAGTRFNVRGLNDEGNVANFVETEQVLSIDKAI
 |....    . . | ||. |   |..   . .... |.. | ..|...    |..|  |||| |. |||||..|||.. ||||||||||||.....||.
alkerslleradeRffwnkhlledlrk.epelesfilPvikGfikikelslnakeikfilisRRsifRaGtRyfvRGvdkeGnvanfvEtEqiveaekal

ASFVQVRGLVPVFWDQPGIQTGTNRIRLSRGfHCSHAAFVRHFESLLSQYGPCLCVDLLGNRDMEPLLTEAYVDHLRNLEEEvpgAAEYVQFDYHGHCRP
.||||||| .|..|.| .      ...||.. . |..|| .|.... ..||....|.|. ..  |  | ||| . .|.|...     .||.||.| .|| 
tsFvqvRGsiPllWsqkpnLkykPkvklses.edsldafkkhldeqielygenvlvnLvdqkGsEkklgeayesvvralnkk...kikyvafDFHkeCrk

KHNEALEtILLPMCSRFIDTCSYYLE-TDGEVVSAQTGVLRVNCLDCLDRSNNSQAMFGQQLLVQQLDGLK---LSSKVNVLSRFKQIFERFWMQNGDNI
 . . |. .|.   ..  .  .|.|  .....|. |.||.| ||.||||| |  |...... | .||. |      ||..  ......|   | .|.|..
mrwdrlk.lLidqlekelsqegyflkseekkivkeqkgvvRtnCiDcLDRtnvvqsllarevLqkqleslgvlateskledsaeletsfknlwadnadav

SKLYAGTRAL-------GSSSKVSKLRNSARSVQRTIVNNFMDSSKQEAIDLLLLN
|. |||| ||       |  ...  ||.   ||.| . |||.|  .|..|||.| .
svqYaGtgAlKtDftRtGkrtllGalrDgvnsvsryyknnfldgerqdsidLflgk
Syja_N SacI homology domain 59-342 5.7e-73 236.8 Pfam-A 1-315 (319) alignment 
Range on Protein: 59-342
Range on HMM: 1-315/319.0
AYALLGVLQVGQsLSYIVLVTGCNQVGRIS-NTEVYQITSTVMVPLHSNPSVH---------------EGVVAMGKLLASGQFYFSVSVDERQNGGLFSL
||..||.... .  ||....|....|..|  . ..|.|.|. ..|| |... .               . .  . ||| ||.|||| ..|  ..    | 
aygilGlirlls.esyllvitkrekvakirgehpiykiksvefiplnseeeessaieeekeeeekeeekllkllkkllssgsfYfSydyDltrslqrkse

LSRSQNR---------GGTTSQFCWNRSLYVYLQRFAVNTDRWVTPLMCGSVQIQTVYAG-DKQVKACLISRVSCERAGTRFNVRGLNDEGNVANFVETE
 ......           . ..|.||| |   |... ....||..||..| |......   .|.|. .|||| |..|||||.. ||..|.||||||||||
keeeekeeeskslpllkevderFvWNrnllkplielkldlsrwllpliqGfveqrsievkskkkveltLIsRrsvkraGtRylrRGidddGnvANfvEtE

QVLSI--D--KAIASFVQVRGLVPVFWDQ-PGIQtGTNRIRLSRGFHCSHAAFVRHFESLLSQYGPCLCVDLLGNRDMEPLLTEAYVDHLRNLE--EEVP
|..|.  .  | . ||||.|| ||.|| | ....  ...|...|  . | .|| .||..|...||....|.||.... |  |.||| .....|.   .  
qivsekkeeskrvfSfvqiRGSvPlfWeqasnls.lkpkikitrsseasqkafkkHfkklikrYgkivvvnLlekkgrEkkLseayeelinklnkklkek

GAAEYVQFDYHGHCRPK
   .|..||.| .|. |
kklkyiefDfhkeckgk
Syja_N SacI homology domain 59-342 5.7e-73 236.8 In-house 1-315 (319) alignment 
Range on Protein: 59-342
Range on HMM: 1-315/319.0
AYALLGVLQVGQsLSYIVLVTGCNQVGRIS-NTEVYQITSTVMVPLHSNPSVH---------------EGVVAMGKLLASGQFYFSVSVDERQNGGLFSL
||..||.... .  ||....|....|..|  . ..|.|.|. ..|| |... .               . .  . ||| ||.|||| ..|  ..    | 
aygilGlirlls.esyllvitkrekvakirgehpiykiksvefiplnseeeessaieeekeeeekeeekllkllkkllssgsfYfSydyDltrslqrkse

LSRSQNR---------GGTTSQFCWNRSLYVYLQRFAVNTDRWVTPLMCGSVQIQTVYAG-DKQVKACLISRVSCERAGTRFNVRGLNDEGNVANFVETE
 ......           . ..|.||| |   |... ....||..||..| |......   .|.|. .|||| |..|||||.. ||..|.||||||||||
keeeekeeeskslpllkevderFvWNrnllkplielkldlsrwllpliqGfveqrsievkskkkveltLIsRrsvkraGtRylrRGidddGnvANfvEtE

QVLSI--D--KAIASFVQVRGLVPVFWDQ-PGIQtGTNRIRLSRGFHCSHAAFVRHFESLLSQYGPCLCVDLLGNRDMEPLLTEAYVDHLRNLE--EEVP
|..|.  .  | . ||||.|| ||.|| | ....  ...|...|  . | .|| .||..|...||....|.||.... |  |.||| .....|.   .  
qivsekkeeskrvfSfvqiRGSvPlfWeqasnls.lkpkikitrsseasqkafkkHfkklikrYgkivvvnLlekkgrEkkLseayeelinklnkklkek

GAAEYVQFDYHGHCRPK
   .|..||.| .|. |
kklkyiefDfhkeckgk
subfamily_FIG4_pd Subfamily FIG4 52-484 6.4e-59 190.8 In-house 63-538 (569) alignment 
Range on Protein: 52-484
Range on HMM: 63-538/569.0
EYPDINTAYALLGVLQVGQSlSYIVLVTGCNQVGRISNTEVYQITSTVMVPLHSNPSVHEG------VVAM-GKLLASGQFYFSVSVDERQNGGLFSL--
 .    .|| .||...  .   |..|||  ..|. | .  .|.|  . ....... . .|        . .  ..  . .|||| | |  .     .|  
glekkvsayGilGfvrfleg.yylilvtkrkkvaviGghaiykiedialikitedskksekssdearylklfkdvdltknfyfsysydltrtlqtnllls

-LSRSQN-------------RGGTTSQFCWNRSLYVYLQRfAVNTDRWVTPLMCGSVQIQTVYAGDKQVKACLISRVSCERAGTRFNVRGLNDEGNVANF
   |...             .  .  .| ||  |.  |.   |.| .|.  .. | |. ...    |... .||.| | . ||.||  || | .|.||| 
dsnrekekaedrvditieakkldanekfvWnnflleplkd.tvktfdWlleiihGfvsqskisvlgksiyvtliarrsskfaGarflkrGvnnkGdvane

VETEQVL-------SIDKAIASFVQVRGLVPVFWDQPGI-QTGTNRIRLSRGFHCSHAAfVRHFESLLSQYG-PCLCVDLLGNRD---MEPLLTEAYVDH
|||||..       . .. ..||||.|| ||..|.|     ..  .|.. .     .||  .||..|...|| | . ..|. ...    |  |.|.. . 
veteqivheasegsldsdryssfvqlrGsvPlyWsqdasklvtkPpikidvvdPfasaa.alhfddlfqryGspiiilnlvkkkekrkresilleefeaa

LRNLEEEVPGA--AEYVQFDYHGHCRPKHNEALETiLLPMCSRFIDTCSYYLE-TDGEVVSAQTGVLRVNCLDCLDRSNNSQAMFGQQLLVQQLDGLKL-
.. | | .|     .|...| .   . |... ||. |  ...... .  ..|. .| | .  |.|..|.||.||||| | .| . |.. |  ||  | . 
ieylneflPeekklkyiswdmaraskskeenvlev.lekyaeksvkktGiflsapdlestkiqeGivrtnCvdcldrtnaaqfvigkvalgyqlkslGii

-SSKVNVLSRFKQIFERFWMQNGDNISKLYAGTRA---LGSSSKVSKLRNS----ARSVQRTIVNNFMDSSKQEAIDLLL
 .||... |   ...| .. . ||...  |.|..    . .  |.... .      ....| . | |.|  ||.||.|.|
desklefdsdvvrlleelyedlGdtlalqygGsqlvntiktyrkiaqwssksrdiletlkryysnsfvdadkqdainlfl
Exo_endo_phos Endonuclease/Exonuclease/phosphatase family 533-811 1.8e-33 106.4 Pfam-A 1-235 (249) alignment 
Range on Protein: 533-811
Range on HMM: 1-235/249.0
GTWNVNGGK----QmrsiALKKESMHDWLLDAPvlsgkksippADVYAigFQELVALTTSNLVS---------TNSSNRYAWAAELQhvlsrdheysllt
.||||.|..    .    | |.. . |.| .            .||..  .|| ..   |.|            ... ....                  
ltwNvlgwnarsdr....akkldqladllqsed..........pDvll..LQEvdedplsellatglaselgldgdgksggggggda.............

aeqlVGVCLYIFVRPHLIPFIRDVGVSAVKTGIG---GAAGNKGGVAIRLLlhSTSLCFVCSHLAAHQTKIV--ERnQDFAEIhRKVLFPMNQTisshdY
    .| .| ....  |   ||.. .. .|.||.   .  ||||.|..|.   ...|..|..||.... .    || ...||| .|.  . ...     .
....gggglallskypldkkirrtfqldgkagiavprlssgnkgdvpvrfr..gktlalvntHltpgnrlrqrder.allaei.dkladdsrgs.....p

VFWCGDLNYRIDLPSsiakdaiskeewdklvrhdqltkqkklgkvfFGFAEGDLTFAPTYKYDQFSDDY-------------DTSEKCRVPAWCDRILWq
|...||.|.|.|.|.                                || |.. .|.|....| .....             ||.||.| ||..|.||. 
vilaGDfNsrpdspd...............................kgfresaadflpgdgfddglrallphlllptspgttdtyekareparlDyilv.

rKSFLPPVTD
  |..| ...
.ssgwpalvv
DUF1866 Domain of unknown function (DUF1866) 881-978 1.8e-20 62.1 Pfam-A 1-104 (146) alignment 
Range on Protein: 881-978
Range on HMM: 1-104/146.0
EIDVFRINEKERERVRGTVLEDMGPADATVRVKPLS------ADYNSIDTKQLVKALNEYGTIVLVRVTDEETCVTFHSAKSAIDAVSFNGQEVNGVAVE
..... .....|..|   |  . || |||. |.  |        ..    ..|.. | ..|...||| ....  |||  ..||....| .| .| |.|..
dveilevdpearravfkeviaaqGPpDativvslksgdedekeifdealieeLlqelaslGeviLvRfvedkmlvtFrdgesALevlslkgikvlgralk

VKLS
..| 
irlK
subfamily_INPP5F_pd Subfamily INPP5F 860-903 3.1e-07 19.9 In-house 809-852 (951) alignment 
Range on Protein: 860-903
Range on HMM: 809-852/951.0
LLYYGRGELKTSDHRPVIAYFEIDVFRINEKERERVRGTVLEDM
| || . |.. |||||| |.| ..|  ..||..  ..  . |..
LeyysdaeilisDHrPvyaafrakvtvvDekkkltLkkklyeey
RRM_1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 921-970 6.4e-06 13.8 Pfam-A 9-66 (70) alignment 
Range on Protein: 921-970
Range on HMM: 9-66/70.0
SIDTKQLVKALNEYGTIVLVRVTD-------EETCVTFHSAKSAIDAVS-FNGQEVNG
... ..| . ....| |. ...             |.|.|  .| .|..  ||....|
dvteeeLkelFskfGpiesiklvrdetgrskgfafVeFeseedaekAlealngkklgg