Gene C13C4.4 in Caenorhabditis elegans

Synonym: CELE_K08B12.3, CELE_K08B12.3

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HAD
Superfamily HAD
Family NagD
Subfamily LHPP
Protein sequence
ID Type Fasta BLAST phosphatome Note
CeleP016_AA protein Get Run
CeleP016_AA_7-259 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_LHPP_pd Subfamily LHPP 10-240 1.5e-94 307.2 In-house 1-227 (227) alignment
Range on Protein: 10-240
Range on HMM: 1-227/227.0
FLLDITGVLYNsiyksDGVAVPKSAEAVNFLYQHS-KVKFLSNAKGNSNRNVARRLQRLGINVREEDVITPAPVVAQYCRENKLRPHLFVRDDVLEYFDG
.|||..|||.|     ...|.|...||...|.|.. ||.|..|.. .|.|....||.|||..|.||...|......|..||.||||.|.|.||| |.|..
vllDlsGvlhn.....edaaipgavealkrLrqagvkvrfvtNttkeskralverLirlgfdveeeeiftsleaarqllrerklrpyllveddveedfed

IDTSSPNCVVMGEVEEGFSFDRINRAFRILIDMPKPLLITMGNGKFFQRVDGPCIDVGAFAAALKFSTNCEVLNIGKPSRFYFEQGMNALGMKPEEIVMV
|||..||.||.|...| |.....|.|||.|....|. ||....||...| || ....|||..||...|.... ..||||...||.....||..|||.||.
idtdkpnavviglapesfeyetlnqafrllleakkakliainkgkyykrkdGlalgpGafvkaleyatgvkaevvGKPsalffekaleelgvdpeeavmi

GDDLMSDVGGAQACGMRGVQVRTGKWRPDFEK
|||...||.||...|.|||.|.|||.||..||
GDdvedDveGAlkaGlrgvlVktGkfrpedek

Chronophin_1 9-254 4.6e-31 99.2 In-house 3-254 (261) alignment
Range on Protein: 9-254
Range on HMM: 3-254/261.0
GFLLDITGVLYNsiyksDGVAVPKSAEAVNFLYQHS-KVKFLSNAKGNSNRNVARRLQRLGIN-VREEDVITPAPVVAQYCRENKLRPHLFV--RDDVLE
 .|||. |||..     .. |||. ||... | |.  .| |..|   . ....| ||.|||.. |..| ... |   |.. |..... . .|   . . .
lvLlDldGVlik.....geeavpgAaeliealkqagkevlfvtNnsrrtreelaarlkrlGldavaaeeifssalaaaallrqqaakakvyvlGeeglrk

YF--DGIDTS-----SPNCVVMGEvEEGFSFDRINRAFRILIDMpkPLLITMGNGKFFQRVDGPCIDVGAFAAALKFSTNCEVLNIGKPSRFYFEQGMNA
 .  .|. .      ... ||.|. .| .||.....| . . |    |..   . . . . .|.    |. |||..  .. | | .|||... ||. .. 
elreaGlrlvdepedrveaVvvGy.deelsfeklaeaialirdg..alfvatnrDptvPleeGiaPgtGslaaaveaAsgreplvvGKPepvmfeealek

LGMKPEEIVMVGDDLMSDVGGAQACGMRGVQVRTGK-WRPDFEKM--PVTPDLTADCLYD
 |..||| ||||| |  |.  .. .|.. . |.||   . . ...  ...||  .. . |
igadpeetvmvGDRldTDilagaraglstllvltGvseleeaqaykkdlrPdavvesiad

subfamily_PGP_pd Subfamily PGP 113-256 1.3e-18 58.3 In-house 129-276 (279) alignment
Range on Protein: 113-256
Range on HMM: 129-276/279.0
SPNCVVMGeVEEGFSFDRINRAFRILIDMPkPLLITMGNGKFFQRVDG-PCIDVGAFAAALKFSTNCEVLNIGKPSRFYFEQGMNALGMKPEEIVMVGDD
. ..||.| |.| .|. .. .| ..| .    |...  . ....  ..    . |...||.. ... . | .|||... .|  ...  ..||  .|.|| 
dvgAVvvg.vdeklsyakllkAanyLrepe.vlflatneDallplkkevvipgaGslvaaieaasgrkplvlGKPnelllelllekeeidpertlmiGDr

LMSDVGGAQACGMRGVQVRTGKWR-PDFEKMPV----TPDLTADCLYDAV
| .|.  ...||.. . | .|  .  | |..      .||. .|.| | .
lktDilfgkncGlqtLlvlsGvtkledveeikkeeklvPdyyldsladll

Hydrolase_like HAD-hyrolase-like 183-255 1.7e-17 54.4 Pfam-A 2-75 (75) alignment
Range on Protein: 183-255
Range on HMM: 2-75/75.0
IGKPSRFYFEQGMNALGMKPEEIVMVGDDLMSDVGGAQACGMRGVQVRTGKWRPDF-EKMPVTPDLTADCLYDA
.|||... ... .. || .|.|.||.||.| .|. .|...|.| . |.||  |..  .. . .|| ..| |..|
lgKPnpgmydkalevlgappsevvmiGDslatDieaAnnaGirsilVltGvsreedlklakakpdyvvddleea

Hydrolase_6 Haloacid dehalogenase-like hydrolase 10-91 1.3e-16 51.9 Pfam-A 1-78 (101) alignment
Range on Protein: 10-91
Range on HMM: 1-78/101.0
FLLDITGVLYNsiyksDGVAVPKSAEAVNFLYQH-SKVKFLSNAKGNSNRNVARRLQRLGINVREEDVITPAPVVAQYCRENK
||.|. |||..     .  |.|..|||...| ..  .| .|.|  ..|....| .|..||..| ||.|.|.| ..|.| ...|
flfDvdGvLwr.....gdkaipgaaealkalraagkpvvllTNnsskseeeyakkleklgvdvteeqvvtsataaaeylkkrk

Chronophin_2 116-232 2.6e-13 40.9 In-house 128-243 (282) alignment
Range on Protein: 116-232
Range on HMM: 128-243/282.0
CVVMGeVEEGFSFDRINRAFRILIDmPKPLLITMGNGKFFQRVDGPCI-DVGAFAAALKFSTNCEVLNIGKPSRFYFEQGMNALGMKPEEIVMVGDDLMS
 |..|  .| ..| .. .|   | | .. ||..  .  .    ||  .   |...|||. ... . . ||||||| ||   . . . | . .|.|| | .
avlvg.ydekltflklakacaylrd.adclllatdrdpwhplsdgritpgsgsltaaletasgrkatvigkpsrfmfecissqfsvdparslmigdrlet

DVGGAQACGMRGVQVRTG
|.   . ||.  |   ||
dilfgsncglstvltltg

subfamily_PGP_pd Subfamily PGP 10-98 1.3e-12 38.6 In-house 2-87 (279) alignment
Range on Protein: 10-98
Range on HMM: 2-87/279.0
FLLDITGVLYNSiyksdGVAVPKSAEAVNFLYQHSK-VKFLSNAKGNSNRNVARRLQRLGIN-VREEDVITPAPVVAQYCRENKLRPHLFV
.|.|. ||| ..       |.|..|||.| | .. | | |..|   .|..........||.. |.||.....| ..|.| ...| . . .|
vlfDcDGVlWlg.....etaipgaaealnaLkklgKkvlfvtNnstksreellkkfkklgfekvkeeeilssaaaiadyLkqkkfekkvyv

HAD_2 Haloacid dehalogenase-like hydrolase 178-229 1e-10 33.5 Pfam-A 126-176 (176) alignment
Range on Protein: 178-229
Range on HMM: 126-176/176.0
CEVLNIGKPSRFYFEQGMNALGMKPEEIVMVGDDLmSDVGGAQACGMRGVQV
..  .  ||.  ..|. .. ||.|||||....| | .|| .|.|.|.|.|.|
sddvgapKpdpeayekvlerlgvkpeeilfidDsl.edveaAraaGirtvhv

Hydrolase haloacid dehalogenase-like hydrolase 168-223 4.9e-07 21.7 Pfam-A 176-215 (215) alignment
Range on Protein: 168-223
Range on HMM: 176-215/215.0
FaaalkfstncevlniGKPSRFYFEQGMNALGMKPEEIVMVGDDLmSDVGGAQACG
.               |||.  .|.. . .|. .|.|..||||..  |. ...|.|
v...............gkPepklfvaaieeLqidpgevamvGDgv.nDapalaaAg

CECR5_TIGR01456 203-259 1.2e-06 18.1 In-house 302-358 (370) alignment
Range on Protein: 203-259
Range on HMM: 302-358/370.0
EEIVMVGDDLMSDVGGAQACGMRGVQVRTGKWRPDFEKMPVTPDLTADCLYDAVKLI
 .. ||||. .||. ||.  |.  . |.|| .    |   . ..|  |   .||. |
kklymvGDnPasDiiGarnaGlfsilvktgvydgadelkegkarlvvdsvseaviki

Chronophin_2 10-90 4.2e-06 17.2 In-house 3-80 (282) alignment
Range on Protein: 10-90
Range on HMM: 3-80/282.0
FLLDITGVLYNSiyksdGVAVPKSAEAVNFLYQHSK-VKFLSNAKGNSNRNVARRLQRLGI-NVREEDVITPAPVVAQYCREN
 |.|  ||..|        ||. ..| |. | .. | | |..|    .  |..... |||. .|..|.... |   |.| |. 
vlfdcdgviwng.....ekavagapevvsrlaragknvlfvtnnstrarenyvlkfarlgfadvaaeqifssaycsaaylrdv