Gene C53A3.2 in Caenorhabditis elegans

Synonym: CELE_K02D10.1, K02D10.1

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HAD
Superfamily HAD
Family NagD
Subfamily PGP
Protein sequence
ID Type Fasta BLAST phosphatome Note
CeleP042_AA protein Get Run
CeleP042_AA_45-341 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_PGP_pd Subfamily PGP 58-342 1.6e-116 379.5 In-house 1-277 (279) alignment 
Range on Protein: 58-342
Range on HMM: 1-277/279.0
TFIFDADGVLWLGESVMPGSPRLIDYLVKHNKQIIVLTNNATKSRAVYAKKLAKLGYNssKMNKNNLVNPAAVVADTLHRAGLDGKrVYLIGEQGLRDEM
|..||.||||||||...||.......| |..|.....|||.||||. ..||..|||..  |.........||..||.|...  ..| ||..||.||..|.
tvlfDcDGVlWlgetaipgaaealnaLkklgKkvlfvtNnstksreellkkfkklgfe..kvkeeeilssaaaiadyLkqkkfekk.vyvlgeeglkeeL

DELGIEYFGHGPEKKQDEADgsGAFMYDIKLEENVGAVVVGYEKHFDYVKMMKASNYLREEGVLFVATNEDETCPGPNpEVVIPDAGPIVAAIKCASGRD
.| |||..|.||||..||.|  ..|....||...|||||||......|.|..||.|||||. |||.|||||...|... |||||.||..||||..||||.
keagiellgtgpeklkdeld..edfveelkldkdvgAVvvgvdeklsyakllkAanyLrepevlflatneDallplkk.evvipgaGslvaaieaasgrk

PLTVGKPCTPAFNYIKRKWNINPSRTMMIGDRTNTDVKFGRDHGMKTLLVLSGCHQIEDIIENQMNErdDMVPDYVAPYLGALVP
||..|||... ......|..|.|.||.|||||..||..||...|..|||||||....||. |....|  ..||||... |..|..
plvlGKPnelllelllekeeidpertlmiGDrlktDilfgkncGlqtLlvlsGvtkledveeikkee..klvPdyyldsladlle
Chronophin_1 58-341 5.2e-65 210.5 In-house 3-256 (261) alignment 
Range on Protein: 58-341
Range on HMM: 3-256/261.0
TFIFDADGVLWLGESVMPGSPRLIDYLVKHNKQIIVLTNNATKSRAVYAKKLAKLGYNSSKmnKNNLVNPAAVVADTLHRAGLdGKRVYLIGEQGLRDEM
....| ||||. ||...|| ..||  | ...|.....|||... |. .|..|..|| .. .  .....  |.  |  |... . . .||..||.|||.|.
lvLlDldGVlikgeeavpgAaeliealkqagkevlfvtNnsrrtreelaarlkrlGldava..aeeifssalaaaallrqqaa.kakvyvlGeeglrkel

DELGIEYFGHGPEkkqdeadgsgafmydikleeNVGAVVVGYEKHFDYVKMMKASNYLREEgVLFVATNEDETCPGPNPevVIPDAGPIVAAIKCASGRD
.| |.   ..  .                    .| ||||||...... |. .|....|.   ||||||.| | | ..   ..| .| ..||.. ||||.
reaGlrlvdeped....................rveaVvvGydeelsfeklaeaialirdg.alfvatnrDptvPleeG..iaPgtGslaaaveaAsgre

PLTVGKPCTPAFNYIKRKWNINPSRTMMIGDRTNTDVKFGRDHGMKTLLVLSGCHQIEDIIENQmnerDDMVPDYVAPYLGALV
|| |||| .  |. . .| ...|..|.|.||| .||...|.. |..|||||.|  . |.. . .    .|..||.|.  .  |.
plvvGKPepvmfeealekigadpeetvmvGDRldTDilagaraglstllvltGvseleeaqayk....kdlrPdavvesiadll
Chronophin_2 58-335 1.6e-61 199.0 In-house 2-271 (282) alignment 
Range on Protein: 58-335
Range on HMM: 2-271/282.0
TFIFDADGVLWLGESVMPGSPRLIDYLVKHNKQIIVLTNNATKSRAVYAKKLAKLGYNSskMNKNNLVNPAAVVADTLHRAGLDGKRVYLIGEQGLRDEM
. .|| |||.| || ...|.| ... |... |... .|||.|..|  |..|.|.||.    ......   |   |  |  .     .|. || .||| |.
nvlfdcdgviwngekavagapevvsrlaragknvlfvtnnstrarenyvlkfarlgfad..vaaeqifssaycsaaylrdvadvrgkvfviggeglrkel

DELGIEYFGHGPEKKqdeadgsgAFMYDIKLEENVGAVVVGYEKHFDYVKMMKASNYLREEGVLFVATNEDETCPGPNPEvVIPDAGPIVAAIKCASGRD
 | |..  ..  |..        | .||. |. .| ||.|||.... ..|. ||. |||.   |..||..|   |  . . ..| .| . ||.. |||| 
reagvpvvedadeqe........asiydcaldpdvravlvgydekltflklakacaylrdadclllatdrdpwhplsdgr.itpgsgsltaaletasgrk

PLTVGKPCTPAFNYIKRKWNINPSRTMMIGDRTNTDVKFGRDHGMKTLLVLSGCHQIEDII---ENQMNERDDMVPDYVAP
 . .|||    |. |  .....|.|..||||| .||. || . |..|.| |.|  ..|.     ..|. |. |.|||||  
atvigkpsrfmfecissqfsvdparslmigdrletdilfgsncglstvltltgvssleeaqeysdsqlaeqrdlvpdyvve
subfamily_LHPP_pd Subfamily LHPP 59-315 1.2e-27 88.3 In-house 1-224 (227) alignment 
Range on Protein: 59-315
Range on HMM: 1-224/227.0
FIFDADGVLWLGESVMPGSPRLIDYLVKHNKQIIVLTNNATKSRAVYAKKLAKLGYNsskMNKNNLVNPAAVVADTLHRAGLdgkRVYLIGEQGLRDEMD
.. |  |||. .....||.   .. | ...... ..||.  .|..  ...| .||..   ....... ........|..  |   | ||. |.. .....
vllDlsGvlhnedaaipgavealkrLrqagvkvrfvtNttkeskralverLirlgfd...veeeeiftsleaarqllrerkl...rpyllveddveedfe

ELGIEYFghgpekkqdeadgsgafmydikleenvGAVVVGY-EKHFDYVKMMKASNYLRE-EGVLFVATNEDETCPGPNPevVIPDAGPIVAAIKCASGR
..  .                              |||.|  ...|.| .. .| . | | ..   .| |..     ..   .. ..|. |.|.. | | 
didtdkp...........................navviglapesfeyetlnqafrllleakkakliainkgkyykrkdG..lalgpGafvkaleyatgv

DPLTVGKPCTPAFNYIKRKWNINPSRTMMIGDRTNTDVKFGRDHGMKTLLVLSGCHQIE
.   ||||    |.   .. ...|.. .|||| .. ||.   . |....|| .| .. |
kaevvGKPsalffekaleelgvdpeeavmiGDdvedDveGAlkaGlrgvlVktGkfrpe
Hydrolase_6 Haloacid dehalogenase-like hydrolase 59-163 1.3e-27 87.2 Pfam-A 1-101 (101) alignment 
Range on Protein: 59-163
Range on HMM: 1-101/101.0
FIFDADGVLWLGESVMPGSPRLIDYLVKHNKQIIVLTNNATKSRAVYAKKLAKLGYNsskMNKNNLVNPAAVVADTLHRAgLDGKRVYLIGEQGLRDEMD
|.|| ||||| |....||...... | ...|....||||..||.. ||||| |||..   ......| .| ..|. |..    .|.|..|||.|||.|..
flfDvdGvLwrgdkaipgaaealkalraagkpvvllTNnsskseeeyakkleklgvd...vteeqvvtsataaaeylkkr.kadkkvlvigeeglreelk

ELGIE
| |..
eaGfk
Hydrolase haloacid dehalogenase-like hydrolase 56-300 1.5e-16 52.7 Pfam-A 1-214 (215) alignment 
Range on Protein: 56-300
Range on HMM: 1-214/215.0
IDTFIFDADGVLWLGESVM--PGSPRLIDYLVKH---------NKQIIVLTNNATKsravyakklaklgynsskmnKNnlVNPAAVVADTLHRAGLDGKr
|.|..|| .|.|. || ..  .|   ..... ..         .. ... ..| |.                    ..  .   |...     .  ||. 
iktvvfDktGTLtegepsvallgnkaalalaaaletgsehpigkavvaaakanstr....................gg..ltgfatfigrgvsgkvdgi.

vYLigeqGLRDEMDELGIEYFGHGPEKKQDEADGSGAFMYDIkleeNVGAVVVGYEKHFDYVKMMKASNYLREEGV-LFVAT-------NEDETCPGPNP
 .|    | .. | .||....     ...... |  .  . .    .. |. |  .    . ....| ..|.|.|. ....|       . . . .| . 
.vl....gnpewmtalglrviapdlvaaegqskgrtvvvvav....qaralgviafadpvkpeaaeavasLkeaGievvlltgdnpetaeaiakqagied

EVVIPDAGpivaaikcasgrdpltvGKPCTPAFNYIKRKWNINPSRTMMIGDRTnTDVKFGRDH
..|  ..                  |||    |... ....|.|....|.||.  .|.....  
slvfaevv.................gkPepklfvaaieeLqidpgevamvGDgv.nDapalaaA
Hydrolase_like HAD-hyrolase-like 262-334 2.4e-14 44.3 Pfam-A 3-69 (75) alignment 
Range on Protein: 262-334
Range on HMM: 3-69/75.0
GKPCTPAFNYIKRKWNINPSRTMMIGDRTNTDVKFGRDHGMKTLLVLSGCHQIEDIIEnqmnerDDMVPDYVA
|||    . .. .. ...||...||||. .||.....  |....|||.| .. ||  .      .   ||||.
gKPnpgmydkalevlgappsevvmiGDslatDieaAnnaGirsilVltGvsreedlkl......akakpdyvv
HAD_2 Haloacid dehalogenase-like hydrolase 257-307 2.2e-06 19.3 Pfam-A 127-176 (176) alignment 
Range on Protein: 257-307
Range on HMM: 127-176/176.0
DPLTVGKPCTPAFNYIKRKWNINPSRTMMIGDRTnTDVKFGRDHGMKTLLV
|   . ||.  |. .. .. ...| ....|.|.   ||. .|. |..| .|
ddvgapKpdpeayekvlerlgvkpeeilfidDsl.edveaAraaGirtvhv
CECR5_TIGR01456 46-106 4.9e-06 16.2 In-house 29-92 (370) alignment 
Range on Protein: 46-106
Range on HMM: 29-92/370.0
PKSFSKVMKTIdTFIFDADGVLWLGESVMPGSPRLIDYLVKHNKQ----IIVLTNNATKSRAVYA
  |. .  |.. .|..| |||| .|.....|..  .  ||... .    ...|||    |    |
kvspessskkf.gfaldiDGvllrGkkpiagaskalrrLvddqGalkiPvllltngGglserara