Gene F20B6.1 in Caenorhabditis elegans

Synonym: CELE_F20B6.1, F20B6.1

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family PTP
Subfamily CelePTP-sf11
Protein sequence
ID Type Fasta BLAST phosphatome Note
CeleP061_AA protein Get Run
CeleP061_AA_31-157 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_Cele-PTP-11_pd Subfamily Cele-PTP-11 28-161 2.8e-95 313.6 In-house 129-262 (312) alignment
Range on Protein: 28-161
Range on HMM: 129-262/312.0
RDNVGFVDLEDHRVYTESCTEIEIGGKSKDKITHRVLKVVVKATGQESKLNHYQWASWPDHGMPDSCDTAHRLLSAVKKDKKPVIAHCSAGVGRTGTLVL
 | ||||||||||||||.||||||||||||||||||||||||||||||||||||||||||||||||||||.|||||||||||||||||||||||||||.|
sdivgfvdledhrvyteycteieiggkskdkithrvlkvvvkatgqesklnhyqwaswpdhgmpdscdtalrllsavkkdkkpviahcsagvgrtgtlal

IESMIAALRHPRKQNVKDSFVLLRKDRARSVRVI
|||||||||||||||||||||||||||||||||.
iesmiaalrhprkqnvkdsfvllrkdrarsvrvf

0050432 (Phosphotyrosine protein) phosphatases II 32-158 3.2e-28 94.4 In-house 161-282 (308) alignment
Range on Protein: 32-158
Range on HMM: 161-282/308.0
GFVDLEDHRVYTESCTEieiggksKDKITHRVLKVVVKATGQESKLNHYQWASWPDHGMPDSCDTAHRLLSAVKKD--KKPVIAHCSAGVGRTGTLVLIE
|..  .. .|.. |...       .| .|.|.|... . .|.. ...|... .||||| |.| .   ..| .|.|   ..|.. |||||||||||.....
gsleygkftvtllseev.......lddytvrtleltnlgdgesrtvthfhytnWpdhgvPpspeilldflelvrkslpggpivVHCsaGvGRtGtfiald

SMIAALRHPRKQNVKDSFVLLRKDRARSV
 ..  |.. .. .| . .  ||. |. .|
llleqlekeggvdvfeavkklReqRpgmv

0036941 (Phosphotyrosine protein) phosphatases II 49-159 4.4e-27 90.6 In-house 147-261 (297) alignment
Range on Protein: 49-159
Range on HMM: 147-261/297.0
IeiggkSKDKITHRVLKVVVKATGQESKLNHYQWASWPDHGMPDSCDTAHRLLSAVKK------DKKPVIAHCSAGVGRTGTLVLIESMIAALR---HPR
.      .| .| |.|.|. . .|.. ...|... .|||||.|.| ..  ... .|.|      ...||. ||||||||.||..... |.  |.   . .
v.....llddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrkvlkllpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeg

KQNVKDSFVLLRKDRARSVR
. .... .  ||. |. .| 
gvdileavkklReqRpgavq

0047943 (Phosphotyrosine protein) phosphatases II 34-158 6.3e-27 90.1 In-house 132-255 (273) alignment
Range on Protein: 34-158
Range on HMM: 132-255/273.0
VDLEDHRVYTESCTEieiggksKDKITHRVLKVVVKATGQESKLNHYQWASWPDHGMPDSCDTAHRLLSAVKK------DKKPVIAHCSAGVGRTGTLVL
.  .. .|.. |...       || .|.|.|... . ||.. . .|... .||||| |.| .   ... .|.|      ...||. |||||||||||...
ltygkftvtllseet.......kddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvrkalealpsngpvvVHCsaGvgRtgtfia

IESMIAALRHPRKQNVKDSFVLLRKDRARSV
.. ..  |.. .. .|.. . |||. |  .|
ldllldqlekeggvdvleavkllrsqRpgmv

0051299 (Phosphotyrosine protein) phosphatases II 35-158 2.3e-26 88.3 In-house 145-269 (288) alignment
Range on Protein: 35-158
Range on HMM: 145-269/288.0
DLEDHRVYTESCTEieiggksKDKITHRVLKVVVK----ATGQESKLNHYQWASWPDHGMPDSCDTAHRLLSAVKKD----KKPVIAHCSAGVGRTGTLV
 ..| .|.. |...       .|..|.|.|.|. .     .|.. . .|... .|||||.||| .   ..| .|.|     ..||. |||||||||||..
tygditvtllseev.......lddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdspellldflrlvrkalasgggpvvVHCsaGvgRtgtfi

LIESMIAALRHPRKQNVKDSFVLLRKDRARSV
... ..  |.. .. .| . .  ||. |  .|
aldllleqlekeggvdvleavkrlreqRpgmv

DSPc_SM00195 50-159 2.9e-26 87.7 In-house 139-246 (263) alignment
Range on Protein: 50-159
Range on HMM: 139-246/263.0
EiggkskDKITHRVLKVVVKATGQESKLNHYQWASWPDHGMPDSCDTAHRLLSAVKKDKK----PVIAHCSAGVGRTGTLVLIESMIAALRHPRKQNVKD
.      |.|. |.|..  ... .. |...||. .|||||.||| .   .||.||||.|.    |.. |||||||||||.|.|....  |..  | ....
k......deiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivVhCsaGvgRtgtfvtidiilskleeekkvdife

SFVLLRKDRARSVR
 .  ||| |...|.
ivkelRkqRpgmvq

PTPc_SM00194 50-159 2.9e-26 87.7 In-house 139-246 (263) alignment
Range on Protein: 50-159
Range on HMM: 139-246/263.0
EiggkskDKITHRVLKVVVKATGQESKLNHYQWASWPDHGMPDSCDTAHRLLSAVKKDKK----PVIAHCSAGVGRTGTLVLIESMIAALRHPRKQNVKD
.      |.|. |.|..  ... .. |...||. .|||||.||| .   .||.||||.|.    |.. |||||||||||.|.|....  |..  | ....
k......deiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivVhCsaGvgRtgtfvtidiilskleeekkvdife

SFVLLRKDRARSVR
 .  ||| |...|.
ivkelRkqRpgmvq

0039614 (Phosphotyrosine protein) phosphatases II 48-158 7.1e-26 86.8 In-house 165-272 (297) alignment
Range on Protein: 48-158
Range on HMM: 165-272/297.0
EieiggksKDKITHRVLKVVVkaTGQESKLNHYQWASWPDHGMPDSCDTAHRLLSAVKK------DKKPVIAHCSAGVGRTGTLVLIESMIAALRHPRKQ
.       .| .|.|.|.|.   .|.. ...|.|. .||||| |.| ..  ..| .|..      ...||. |||||||||||....  |.  |.. .. 
h.......ldgytvrtlevtn..ngesrtvthfqytgwpdhgvppslellleflelvrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggv

NVKDSFVLLRKDRARSV
.|.. .  ||. |  .|
dvleavkelreqRpgav

0040438 (Phosphotyrosine protein) phosphatases II 42-159 7.7e-26 86.5 In-house 146-260 (317) alignment
Range on Protein: 42-159
Range on HMM: 146-260/317.0
YTESCTEieiggksKDKITHRVLKVVVKATGQESKLNHYQWASWPDHGMPDSCDTAHRLLSAVKKD----KKPVIAHCSAGVGRTGTLVLIESMIAALRH
 . |..|       .. ||.|.|.|. . .... ...|... .||||| |.| |.  ..|.||..     ..||. |||||||||||..... |.  |..
tllseee.......lagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavrealedpggpvlVHCsaGvgRtGtfiaaylmleqlek

PRKQNVKDSFVLLRKDRARSVR
 .. .|.. .  ||. |. .| 
eggvdveeavkelreqRpgavq

0046845 (Phosphotyrosine protein) phosphatases II 36-159 9.6e-26 86.2 In-house 132-258 (284) alignment
Range on Protein: 36-159
Range on HMM: 132-258/284.0
LEDHRVYTESCTEieiggksKDKITHRVLKVVVKA-TGQESKLNHYQWASWPDHGMPDSCDTAHRLLSAVKKD------KKPVIAHCSAGVGRTGTLVLI
..| .|.. |...       || .|.|.|... .  ||.. ...|... |||||| |.| .   ..| .|..       ..|.. |||||||||||....
ygdftvtllseev.......kddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrellenlpgggpivVHCsaGvgRtGtfial

ESMIAALRHPR---KQNVKDSFVLLRKDRARSVR
. ..  |.. .   . .| . .  ||. |  .| 
dllleqlekeglllgvdvleavkrlreqRpgmvq

0045450 (Phosphotyrosine protein) phosphatases II 42-158 1.7e-25 85.9 In-house 165-287 (307) alignment
Range on Protein: 42-158
Range on HMM: 165-287/307.0
YTESCTEIEIggksKDKITHRVLKVVVK-ATGQESKLNHYQWASWPDHGMPDSCDTAHRLLSAVKK------DKKPVIAHCSAGVGRTGTLVLIESMIAA
.|  ....|.    .|..|.|.|.|  .  ||.. ...|... .||||| |.| ... ... .|.|      ...||. |||||||||||....  |.  
ftvtllseeh....ldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfeelldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrq

LRHPRK---QNVKDSFVLLRKDRARSV
|..  .    .. . . |||. |  .|
lekegtlldvdlleavkllreqRpgav

0040439 (Phosphotyrosine protein) phosphatases II 45-158 5.3e-25 83.9 In-house 117-229 (249) alignment
Range on Protein: 45-158
Range on HMM: 117-229/249.0
SCTEieiggksKDKITHRVLKVVVKATGQESKLNHYQWASWPDHGMPDSCDTAHRLLSAVKK------DKKPVIAHCSAGVGRTGTLVLIESMIAALRHP
|...       ||..|.|.|... . .|.. . .|.|. .||||| |.| ... ... ||.|      ...||. |||||||||||....  |.  |.. 
svev.......kddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylmleqleke

RKQNVKDSFVLLRKDRARSV
.. .... . |||. |  .|
lgvdleeavkllrsqRpgav

0043336 (Phosphotyrosine protein) phosphatases II 51-158 7.3e-25 83.4 In-house 153-260 (278) alignment
Range on Protein: 51-158
Range on HMM: 153-260/278.0
IggksKDKITHRVLKVVVKATGQESKLNHYQWASWPDHGMPDSCDTAHRLLSAVKK----DKKPVIAHCSAGVGRTGTLVLIESMIAALRHPRKQNVKDS
     .| .|.|.|.|. . .|.. . .||.. .||||| |.| ..  ..| ||..    ...||. |||||||||||..... ..  |.. .. .. . 
h....lddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldflkavrealedsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleea

FVLLRKDRARSV
.  ||. |. .|
vkelreqRpgav

0042113 (Phosphotyrosine protein) phosphatases II 43-158 1.8e-24 81.9 In-house 110-226 (245) alignment
Range on Protein: 43-158
Range on HMM: 110-226/245.0
TESCTEIEIggksKDKITHRVLKVVVKATGQESKLNHYQWASWPDHGMPDSCDTAHRLLSAVKK-----DKKPVIAHCSAGVGRTGTLVLIESMIAALRH
|  ....|.    .|..|.|.|.|. . .... . .||.. .|||||.||. ..  ..|..|.|     ...||. |||||||||||....  |.  |..
tvtllseeh....lddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleqlek

PRKQNVKDSFVLLRKDRARSV
 .. .. . .  ||. |  .|
elgvsleeavkelrsqRpgav

Y_phosphatase Protein-tyrosine phosphatase 35-159 2.1e-24 81.6 Pfam-A 89-221 (235) alignment
Range on Protein: 35-159
Range on HMM: 89-221/235.0
DLEDHRVYTESCTEIEIG-GKS--KDKITHRVLKVVVKATGQ-ESKLNHYQWASWPDHGMPDSCDTAHRLLSAVKKDK----KPVIAHCSAGVGRTGTLV
. |... .|    ..|.   ..  ....| |.|..  |.. . . ....... .|||||.|.| .   .|. .|.|.|    .||. |||||||||||.|
peeeeesltygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfv

LIESMIAALRHPRKQNVKDSFVLLRKDRARSVR
... ..  |.. .. .|..    ||| |. .| 
aldilleqleaeeevdvlqivkelRkqRpgmvq

Y_phosphatase Protein-tyrosine phosphatase 35-159 2.1e-24 81.6 In-house 89-221 (235) alignment
Range on Protein: 35-159
Range on HMM: 89-221/235.0
DLEDHRVYTESCTEIEIG-GKS--KDKITHRVLKVVVKATGQ-ESKLNHYQWASWPDHGMPDSCDTAHRLLSAVKKDK----KPVIAHCSAGVGRTGTLV
. |... .|    ..|.   ..  ....| |.|..  |.. . . ....... .|||||.|.| .   .|. .|.|.|    .||. |||||||||||.|
peeeeesltygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfv

LIESMIAALRHPRKQNVKDSFVLLRKDRARSVR
... ..  |.. .. .|..    ||| |. .| 
aldilleqleaeeevdvlqivkelRkqRpgmvq

0045098 (Phosphotyrosine protein) phosphatases II 36-158 3e-23 78.0 In-house 118-255 (278) alignment
Range on Protein: 36-158
Range on HMM: 118-255/278.0
LEDHRVYTESCTEIeiggkskDKITHRVLKVVVK----ATGQESKLNHYQWASWPDHGMPDSC--DTAHRLLSAVKK-----------------DKKPVI
 .| .|...|....       |..|.|.|.|.      ..... ...|... .||||| |..   .   .||  ...                 ...||.
ygdftvtllseevl.......ddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvl

AHCSAGVGRTGTLVLIESMIAALrhPRKQNVKDSFVLLRKDRAR-SV
 |||||||||||||..  |.  |  ... .. . .  ||. |   .|
VHCsaGvgRtGtlvaaylmlell..eggvdlleavkelrsqRpglav

subfamily_Cele-PTP-20_pd Subfamily Cele-PTP-20 54-162 3.8e-23 76.5 In-house 162-270 (290) alignment
Range on Protein: 54-162
Range on HMM: 162-270/290.0
KSKDKITHRVLKVVVKATGQESKLNHYQWASWPDHGMPDSCDTAHRLLSAVKKDKKPVIAHCSAGVGRTGTLVLIESMIAALRHPRKQNVKDSFVLLRKD
.  ..| ...| |  | .|.| ||.|..  ||||. .. |  .  |.| ...|   ||. |||||.|||||.| ||  .  | . .. .. |    ||. 
dkdaniikktlsvrdkdsGkehklkhlkikswpdksvalstlallrtlrilrkasGpvvvhcsaGiGrtGtfvaievglqilldGkeldlldlvralrns

RARSVRVII
|. ||.| |
rlnsvqvdi

PTPc_DSPc_SM00012 77-159 1.1e-22 75.5 In-house 2-91 (105) alignment
Range on Protein: 77-159
Range on HMM: 2-91/105.0
LNHYQWASWPDHGMPDSCDTAHRLLSAVKKDKK------PVIAHCSAGVGRTGTLVLIESMIAALRHP-RKQNVKDSFVLLRKDRARSVR
..||.. .|||||.|...|   .|| |||| |.      ||. |||||||||||.|... ..  |..  .. .... .  ||| |...|.
vkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvq

subfamily_Cele-PTP-6_pd Subfamily Cele-PTP-6 41-131 3.7e-22 73.7 In-house 142-232 (307) alignment
Range on Protein: 41-131
Range on HMM: 142-232/307.0
VYTESCTEIEIGGKSKDKITHRVLKVVVKATGQESKLNHYQWASWPDHGMPDSCDTAHRLLSAVKKDKKPVIAHCSAGVGRTGTLVLIESM
  | | ... ..  . |.    | .. |. ...   ..|.||  |||.|.|.   ||  ||.||. |. ||. ||||||||.||.| |  .
pntisvanlgakklapdedlinvttlkvdwaqksrtiqhlqwenwpdrgvpqinltainlleavrydtnpvvvhcsaGvGrsGtivaislv

0037934 (Phosphotyrosine protein) phosphatases II 52-157 6.5e-22 73.7 In-house 109-224 (243) alignment
Range on Protein: 52-157
Range on HMM: 109-224/243.0
GGKSKDKITHRVLKVVVKA-TGQESKLNHYQWASWPDHGMPDSCDTAHRLLSAVK------------KDKKPVIAHCSAGVGRTGTLVLIESMIAALrhp
. ...|..|.|.|... .  ....    ||.. .|||||.|||..   ..|..|.            ....||. ||||||||||||...  |.  |   
seehlddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtliaaylmllll...

rKQNVKDSFVLLRKDRAR-S
 . .. . . |||. |   .
.gvdleeavkllreqRpgka

subfamily_Cele-PTP-18_pd Subfamily Cele-PTP-18 40-155 2.2e-21 70.9 In-house 152-267 (305) alignment
Range on Protein: 40-155
Range on HMM: 152-267/305.0
RVYTESCTEIEIGGKSKDKITHRVLkVVVKATGQESKLNHYQWASWPDHGMPDSCDTAHRLLSAVKKDKKPVIAHCSAGVGRTGTLVLIESMIAALRHPR
 |  ||......  ..| |.|. || |.  . ..  | .|| |  ||| |.| .  .   ||   .  | |.. |||||.||||..|..| ..  |   .
svkfessvtlkfrkdakakvtetvl.viegpgekarkvthyhwidwpdrgvpaadlailellekarpskgpivvhcsagigrtgsvvmleyildqllagq

KQNVKDS-FVLLRKDRA
. .  |  .. .|..| 
iiedtdkilqkireqrn

subfamily_PTPRB_pd Subfamily PTPRB 60-156 4.1e-21 70.3 In-house 163-266 (293) alignment
Range on Protein: 60-156
Range on HMM: 163-266/293.0
T-HRVLKVVVKATGQESKLNHYQWASWPDHGMPDSCDTAHRLLSAVKKD------KKPVIAHCSAGVGRTGTLVLIESMIAALRHPRKQNVKDSFVLLRK
. . . .. .. . .| |...|.. ||||||.|.. .|  ... .|..       |.|...|||||||||||.. .. .. |...    ..    . ||.
edwvirelkiekekeerkvrqyhftsWpdhgvPektktlldfvrtvreaiektaskrPivvhCsaGvGRtGtfialdrllqaieeedyvdifgivaelRe

DRAR
.|. 
eRnl

subfamily_PTPRD_pd Subfamily PTPRD 57-157 5.3e-21 69.9 In-house 159-263 (564) alignment
Range on Protein: 57-157
Range on HMM: 159-263/564.0
DKITHRVLKVVVKATGQESKLNHYQWASWPDHGMPDSCDTAHRLLSAVK----KDKKPVIAHCSAGVGRTGTLVLIESMIAALRHPRKQNVKDSFVLLRK
 ... | .|.  | . .  . ..... ||||||.|.|  .  .|.. |.    .|..|.. ||||||||||| . |..|.  ... .. ..     .|||
adyeirtfklkkkkssesreVrqFhFtsWPdhgvpesatslLdlirkvralnepdagPivVhCSaGVGRTGtfividamlerikeektvDiyqyvkalrk

DRARS
.|   
qRnam

subfamily_Nvec-PTP-2_pd Subfamily Nvec-PTP-2 56-159 1.1e-20 68.9 In-house 118-226 (250) alignment
Range on Protein: 56-159
Range on HMM: 118-226/250.0
KDKITHRVLKVVVKATGQESKLNHYQWASWPDHGMPDSCDTAHRLLSAVKK-----DKKPVIAHCSAGVGRTGTLVLIESMIAALRHPRKQNVKDSFVLL
.  .|.|.||.  .   .|  . .... .||| |.|.   ..  ||. |..     ...||| .|||||||.|. . |....  |.. .. .| .    |
fadytkrklklskakkaderivrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidavlerlkkekvvdvfkvikvl

RKDRARSVR
|||| ..|.
rkdrphave

subfamily_PTPN13_pd Subfamily PTPN13 54-157 1.9e-20 68.3 In-house 145-251 (273) alignment
Range on Protein: 54-157
Range on HMM: 145-251/273.0
KSKDKITHRVLKVVVKATGQESKLNHYQWASWPDHGMPDSCDTAHRLLSAV---KKDKKPVIAHCSAGVGRTGTLVLIESMIAALRHPRKQNVKDSFVLL
. .|  . | |.|  ...|.  .. | ....|||||.| | .   .... |   ..|. |.. |||||.||.|||. |. ..  . . .. .||.    |
qkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaellqfvaevrrlqtdagPivvhcsaGiGrsGtlitidvvlglierdkefdvkeivrkl

RKDRARS
|. |   
reqrqgv

subfamily_Cele-PTP-8_pd Subfamily Cele-PTP-8 46-160 2.3e-20 67.8 In-house 142-256 (288) alignment
Range on Protein: 46-160
Range on HMM: 142-256/288.0
CTEIEIGGKSKDKITHrVLKVVVKATGQESK-LNHYQWASWPDHGMPDSCDTAHRLLSAVKKDKKPVIAHCSAGVGRTGTLVLIESMIAALRHPRKQNVK
|| .    .  ||. . |  . .. .|.|.. . .  .  |.|.|.|..  .  |||  .|. .||.. |.||||||||||.||  .. .|| .    ..
ctvvkkkradidklvk.vsllriskegeekvivkilhlleWdddgvPenylsplrllevlkslqkPivvhssaGvGrtgtlililialeslrlddflgir

DSFVLLRKDRARSVRV
  .  ||..| .....
sllaklreerfkaiqt

subfamily_PTPN12_pd Subfamily PTPN12 42-158 3e-20 67.3 In-house 139-260 (290) alignment
Range on Protein: 42-158
Range on HMM: 139-260/290.0
YTESCTEIEIGGKSKDKITHRVLKVVVKatGQESKLNHYQWASWPDHGMPDSCDTAHRLLSAVK----KDKKPVIAHCSAGVGRTGTLVLIESMIAALRH
. | . . |   . .| .. | ||| ..  ... |.. ... .|||||.| | ..  .|...|.    ....|.. |||||||||||.. |. .  .|..
fgefevtleeekavdddflirtLkveaq..kesrkvyqfhYtaWPDhgvPssaksllelielvrelqesedaPlvvhCsaGvGrtGtiiaidyvrellka

PRK---QNVKDSFVLLRKDRARSV
 .     .| |  . |||.||  |
ekipeeldvfdlvlelrkqraalv

subfamily_Choan-PTP-2_pd Subfamily Choan-PTP-2 61-158 3.8e-20 67.0 In-house 138-247 (270) alignment
Range on Protein: 61-158
Range on HMM: 138-247/270.0
HRVLKVVVKATGQESKLNHYQWASWPDHGMPDSCD---TAH---RLLSAVK-----KDK-KPVIAHCSAGVGRTGTLVLIESMIAALRHPRKQNVKDSFV
... .. .. .|.| .| |... .|||||.| . |   ...   ..| ||.     .|| .|.. ||||||||||||.... .. .| . .| .|     
yiltrlrleekgeerrlvHfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcsaGvgRtGtlialDiavrlLeetkkvdvlaiie

LLRKDRARSV
 |||||   |
elRkdRmalv

subfamily_Cele-PTP-10_pd Subfamily Cele-PTP-10 63-159 6.7e-20 65.9 In-house 177-273 (305) alignment
Range on Protein: 63-159
Range on HMM: 177-273/305.0
VLKVVVkATGQESKLNHYQWASWPDHGMPDSCDTAHRLLSAVKKDKKPVIAHCSAGVGRTGTLVLIESMIAALRHPRKQN-VKDSFVLLRKDRARSVR
.|..   . .|.  . | ||. ||| |.|    |.  ||||..  | |.. |||||.|||||.| || ..  .   ..   . .    || .|| |..
llnlty.sgdqkmsvrhlqwtewpdrgvppckltslellsairgskvpivvhcsagigrtgtivaieyilekiaenkpcppmpelvkalrdqrafsiq

subfamily_Urchin-PTPRB-like_pd Subfamily Urchin-PTPRB-like 51-160 8.5e-20 66.0 In-house 153-264 (288) alignment
Range on Protein: 51-160
Range on HMM: 153-264/288.0
IGGKSKDKITHRVLKVVvkATGQESKLNHYQWASWPDHGMPDSCDTAHRLLSAVK----KDKKPVIAHCSAGVGRTGTLVLIESMIAALRHPRKQNVKDS
.. | ......| | ..   ...| ....||. .|||||.|.|      ||. ||    .| .|.| ||||||||||| . .. .| |...  . .| . 
veskeledfvlrkllle..kkkteleitqyqylaWpdhgvPeskapllellrqvkvanqadtgpiivhCsaGvGrtgtFialdalidaveeedyiDvagt

FVLLRKDRARSVRV
   ||| ||  | .
vaklRkqRallvqt

subfamily_Choan-PTP-1_pd Subfamily Choan-PTP-1 53-160 1.3e-19 65.4 In-house 149-261 (281) alignment
Range on Protein: 53-160
Range on HMM: 149-261/281.0
GKSKDKITHRVLKVvVKATGQESKLNHYQWASWPDHGMPDSCDTAHRLLSAV-----KKDKKPVIAHCSAGVGRTGTLVLIESMIAAL-RHPRKQNVKDS
 ..| .  .|..|.  . .|.. .... .. .|||||.|..        ..|     || | |.. ||||||||||| . .. .. |. .. .. .||. 
eeekatyierkfkl.eresgetreveqlaytaWPdhGvPattkellefrkevlkltekktkaplvihCsaGvGrtGtyialDrlvkaveaeleeldvkav

FVLLRKDRARSVRV
   |||.|   |. 
vaelrkernlmvqt

0043147 (Phosphotyrosine protein) phosphatases II 67-158 4.6e-19 64.2 In-house 55-144 (172) alignment
Range on Protein: 67-158
Range on HMM: 55-144/172.0
VVKATGQESKLNHYQWASWPDHGMPdSCDTAHRLLSAVKK-----DKKPVIAHCSAGVGRTGTLVLIESMIaalrhpRKQNVKDSFVLLRKDRARSV
.. ... |    .|.. .||||| | . .   ..|. ...     ...||. |||||||||||||..  |.      .. .. . . |.|. |  .|
lydpellerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml......lglsleeavalvrekRpgav

0041856 (Phosphotyrosine protein) phosphatases II 71-158 5.7e-19 63.8 In-house 73-154 (182) alignment
Range on Protein: 71-158
Range on HMM: 73-154/182.0
TGQESKLNHYQWASWPDHGMPDsCDTAHRLLSAVKKDKKPVIAHCSAGVGRTGTLVLIESMIAAlrhprKQNVKDSFVLLRKDRARSV
.  |    .|.. .||||| ||  |...... .|.....||. |||||||||||||..  |.       . .. . . |.|. |  .|
ellerlgiqylylpwpDhgvpd.ldelldfieevleeggpvlVHCsaGvgRtgtlvaaylmkkl.....gvsleeavklvrsrRpgmv

subfamily_Anemone-PTP-2_pd Subfamily Anemone-PTP-2 55-159 6.2e-19 63.3 In-house 165-274 (298) alignment
Range on Protein: 55-159
Range on HMM: 165-274/298.0
SKDKITHRVLKVVVKATGQESKLNHYQWASWPDHGMPDSCDTAHRLLSAVKKD-----KKPVIAHCSAGVGRTGTLVLIESMIAALRHPRKQNVKDSFVL
.. ... | |||  | . .| .. . .. ||||.|.|    .   ||. |..      .|||| .|||||||.|| . |.|..  ... ..  | .    
efadlivrklkvskkkeekerevrqlhftsWpdkgvpenatsvldllrkvrasqqqagnkpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkv

LRKDRARSVR
|||.|. .|.
lRkkrpgavq

0051429 (Phosphotyrosine protein) phosphatases II 56-158 1.9e-18 62.6 In-house 100-208 (272) alignment
Range on Protein: 56-158
Range on HMM: 100-208/272.0
KDKITHRVLKVVVK-ATGQESKLNHYQWASWPDHGMPDSCdtAHRLLSAVKKdKKPVIAHCSAGVGRTGTLVLIESMIAALRHPRKQN--------VKDS
.. ...|.| .. .  .|.  .. |... .||||| |..    ..||... . ..||. |||||..||||.|..  ... . .    .        . . 
lldyilrellltlllsagearevmhlhytdwpdhgvpqea..llellellld.ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlyleea

FVLLRKDRARSV
   ||. |. .|
veelraqrpgav

subfamily_PTPN3_pd Subfamily PTPN3 54-157 2e-18 61.3 In-house 150-257 (280) alignment
Range on Protein: 54-157
Range on HMM: 150-257/280.0
KSKDKITHRVLKVVVKATGQESKLNHYQWASWPDHGMPDSCDTAHRLLSAVKKDK----KPVIAHCSAGVGRTGTLVLIESMIAALRHPRKQNVKDSFVL
... ..  | | .  |.| .| |. . |. .|||||.||. .   .... |.| .    .||. |||||.|||| |.|.|  .| . . .. .. |    
detksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklrsgkeePvvvhCsaGigrtGvlilletalalieaaepvypldivrt

LRKDRARS
.|  ||  
mrdqraml

subfamily_Sponge-PTP8_pd Subfamily Sponge-PTP8 56-158 2.9e-18 61.1 In-house 158-266 (305) alignment
Range on Protein: 56-158
Range on HMM: 158-266/305.0
KDKITHRVLKVVVKATGQES-KLNHYQWASWPDHGMPDSCDTAHRLLSAVKK----DKK-PVIAHCSAGVGRTGTLVLIESMIAALRHPRKQNVKDSFVL
    . | ||. .. . .||  . .||  .|||||.|..  .  .|.  |.|    ||. |.. ||||||||||. . .. ..  |..    .| .    
asdyieRklkisiededkesrtvlqyqltdWPdhGvpqfatsllslikrvqkdqkkdkgvpllVhCsagvgRtGvfiavdialerlkkEevvdvfevlkq

LRKDRARSV
||. |   |
lRskrmkmv

subfamily_Cele-PTP-19_pd Subfamily Cele-PTP-19 56-159 3.3e-18 60.4 In-house 161-265 (301) alignment
Range on Protein: 56-159
Range on HMM: 161-265/301.0
KDKITHRVLKVVVKATGQES-KLNHYQWASWPDHGMPDSCDTAHRLLSAVKKDKKPVIAHCSAGVGRTGTLVLIESMIAALRHPRKQNVKDSFVLLRKDR
..||..| |.|.  .   ..  . |||...|.|.|.| |    . |.  ||| .||.. |||||.||. ...  | .  ..   .. ......  ||..|
nkkiskrtlevedstgkfatrtvthyqysewtdrgvPkshaelfdlmelvkksekPivvhcsaGiGrsvafigteylareveadptieltealkhlrehr

ARSVR
 ..|.
wngvq

subfamily_PTPN14_pd Subfamily PTPN14 56-159 6.5e-18 59.7 In-house 164-280 (300) alignment
Range on Protein: 56-159
Range on HMM: 164-280/300.0
KDKITHRVLKVVVKATGQESKLNHYQWASWPDHGMPDSCDTAHRLLSAVK-------------KDKKPVIAHCSAGVGRTGTLVLIESMIAALRHPRKQN
 |... . ||.    ...| .. | |.. |||||.|.  ..    |  |.             . | ||. |||||||||| |.| . .||.| | .. .
sdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseveskeskPPvlvhCsaGvGrtGvlilsdlliatlehneeid

VKDSFVLLRKDRARSVR
.| ..  ||. |   |.
ikkvlarLreqrmllvq

subfamily_PTPN23_pd Subfamily PTPN23 54-158 1.1e-17 58.8 In-house 150-263 (288) alignment
Range on Protein: 54-158
Range on HMM: 150-263/288.0
KSKDKITHRVLKVVVKATGQESKLNHYQWASWPDHGMPDSCDTAHRLLSAVKK--------DKKPVIAHCSAGVGRTGTLVLIESMIAALR-HPRKQNVK
.. ..  .||||. .. . .  .. | |. |||..|.|.| .|  ..| .|..         |.|.. ||||||||||.. |. . ...|. ..   .. 
retethvervlkletldadavksvshlqltsWpelGvPasPetllqfldevesayeavqrksktPlvvhCsaGvgRtgvfalvyaavrelekgnglldii

DSFVLLRKDRARSV
. .  ||..|  .|
qvvsrlreqRrfmv

subfamily_PTPN6_pd Subfamily PTPN6 53-159 1.2e-17 58.9 In-house 163-281 (306) alignment
Range on Protein: 53-159
Range on HMM: 163-281/306.0
GKSKDKITHRVLKVV-VKATGQESKLNHYQWASWPDHGMPDSCDTAHRLLSAVKK--------DKKPVIAHCSAGVGRTGTLVLIESMIAALRHPR---K
 ||... . | |.|  .|  ..| .. .|.. ||||||.| . ..   .|. |..        .. |.. |||||.|||||...|. ..  ...     .
eksladYilRelsvskkkkkkeerevfqyhfksWPdhgvpkdpgavLdfledvnrkqeeleeaeagpivvhCsaGiGRtGtfiviDillkliekkgldad

QNVKDSFVLLRKDRARSVR
 .....  ..|. |   |.
idiqklvksvreqrsglvq

0049260 (Phosphotyrosine protein) phosphatases II 68-158 2e-17 58.8 In-house 55-133 (152) alignment
Range on Protein: 68-158
Range on HMM: 55-133/152.0
VkatgqesklnHYQWASWPDHGMPDSCDTAHRLLSAV----KKDKKPVIAHCSAGVGRTGTLVLIESMIaalrhpRKQNVKDSFVLLRKDRARSV
           .|..  ||||| ||. .    || ..    .....||. |||||||||||||..  |.      .. .... . |.|. |  .|
i..........qylhlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgav

subfamily_Anemone-PTP-5_pd Subfamily Anemone-PTP-5 58-155 2.1e-17 58.2 In-house 160-260 (319) alignment
Range on Protein: 58-155
Range on HMM: 160-260/319.0
KITHRVLKVVVKATGQE-SKLNHYQWASWPDHGMPDSCDTAHRLLS----AVKK-DKKPVIAHCSAGVGRTGTLVLIESMIAALrhpRKQNVKDSFVLLR
..  | ||.  |..  |  .. |.|. .||||..|..  .   ||     ...| ...|.. ||||||||||| . .. |.  .   ....| | |   .
dyiirklklnkkssevetRevkhfqyteWpdhdvPekatslldllkrirksrektqsgPivvhCsaGvGRtGtfivldamlerv...keegvlDvfstvs

KDRA
. |.
rlRt

0048076 (Phosphotyrosine protein) phosphatases II 63-157 2.4e-17 58.4 In-house 33-125 (145) alignment
Range on Protein: 63-157
Range on HMM: 33-125/145.0
VLKVVVKATGQESKLNHYQWASWPDHGMPDSCDTAHRLLSAV---KKDKKPVIAHCSAGVGRTGTLVLIESMIAalrhpRKQNVKDSFVLLRKDRARS
|| .    .. | .  .|.. .||||| ||. ..  ..| ..    |...||. |||||||||||||..  |.      .. .. . . |.|. |  .
vlnltselellerlgiqylylpwpDhgvpdllellleflefieealkeggpvlVHCsaGvgRtgtlvaaylmll.....lgvsleealelvrsqrpga

subfamily_Anemone-PTP-6_pd Subfamily Anemone-PTP-6 57-158 3e-17 57.7 In-house 157-263 (318) alignment
Range on Protein: 57-158
Range on HMM: 157-263/318.0
DKITHRVLKVVVKATGQESKLNHYQWASWPDHGMPDSCDTAHRLLSAVKK-----DKKPVIAHCSAGVGRTGTLVLIESMIAALRHPRKQNVKDSFVLLR
.. . | .||  . . .. .   |...||||.|.|.|  .   |.  |.|     ...|.. ||||||||||. . .....  ...    .| .    ||
sdyvlrefkvtrteeeesrqvrqyhytsWpdegvpesgaslldlvrqvskaqqksgagpivvhCsaGvGrtGvfiavdillerikaealvDvfqtvkqlr

KDRARSV
. |   |
eqrnlmv

0036282 (Phosphotyrosine protein) phosphatases II 71-157 4e-17 57.9 In-house 63-152 (174) alignment
Range on Protein: 71-157
Range on HMM: 63-152/174.0
TGQESKLNHYQWASWPDHGMPDSCDtAHRLLSAVKKD-----KKPVIAHCSAGVGRTGTLVLIESMIAALRhPRKQNVKDSFVLLRKDRARS
.  |    .|..  |||||.||.    ......|..      ..||. |||||||||||||..  |.  |. .. ... | .  ||. | ..
edlerlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgm

subfamily_PTPN5_RR_pd Subfamily PTPN5_RR 45-155 1e-16 55.9 In-house 130-248 (274) alignment
Range on Protein: 45-155
Range on HMM: 130-248/274.0
SCTEIEIGGKS-KDKITHRVLKVVVKATGQESKLNHYQWASWPDHGMPDSCDTAHRLLSAVKKDK-----K--PVIAHCSAGVGRTGTLVLIESMIAALR
  ...||  .. ...  ..| |.|.| . .| .. || ...||||  ||. .|  .|.  |....     |  ||. |||||.||||  . |.  .  ||
rygdveikvekiverndysvrklvlkylerersvkhywytdWPdhksPddantlldlvleveesreeenaklapvvvhCsaGiGrtGcfiaisiavrqlr

HPRKQNVKDSFVLLRKDRA
.  . .|    . || || 
eeivvdvlkivcnlrldrG

subfamily_PTPN1_pd Subfamily PTPN1 54-154 1.7e-16 54.8 In-house 141-250 (290) alignment
Range on Protein: 54-154
Range on HMM: 141-250/290.0
KSKDKITHRVLKVVVKATGQESKLNHYQWASWPDHGMPDSCDTAHRLLSAVK------KDKKPVIAHCSAGVGRTGTLVLIESMIAALRHPRK---QNVK
..|.. | |.|..  . | .  .. |. . .||| |.|.|  .  ..|  |.      .|. |.. |||||.||.||..|...... . .  .    ..|
erksyytvrllelenlktqetreilhfhyttwpdfgvpespaaflkflfkvresGslssdvGpavihcsaGiGrsGtfclvdtclvliekkddlssvdik

DSFVLLRKDR
. .. ||| |
kvllelrkyr

subfamily_Urchin-PTP-1_pd Subfamily Urchin-PTP-1 60-158 1.7e-16 55.0 In-house 160-260 (315) alignment
Range on Protein: 60-158
Range on HMM: 160-260/315.0
THRVLkvVVKATGQESKLNHYQWASWPDHGMPDSCDTAHRLLSAVKKDKK----PVIAHCSAGVGRTGTLVLIESMIAALRHPRKQNVKDSFVLLRKDRA
..| |  |.. . .  ..  .|.  |||.| .    .  .|. .|| |..    ... |||||||||| .. |....| ... |  .| .    ||..| 
varkl..vtrkseesrtvtqfqftewPdkGvdkqtssllklikevkadngkkefsllvhcsaGvGrtGvvisidevvaqikrtrsvdvfnfvknlrakrp

RSV
  |
ylv

0051082 (Phosphotyrosine protein) phosphatases II 74-153 1.7e-16 55.6 In-house 57-131 (151) alignment
Range on Protein: 74-153
Range on HMM: 57-131/151.0
ESKLNHYQWASWPDHGMPDSCDTAHRLLSAVKKD-KKPVIAHCSAGVGRTGTLVLIESMIaaLRhprkQNVKDSFVLLRKD
. .. |... .|||.|.|.| |.. ..|... .. ..||. |||||.|||||||..  |.  |.     .. . .  .|. 
gievlhipildwpdpglplsfdavleflellldkkngpvlvHCsaGkgRTGtlvalylml..lg....vsleealeeyrlk

0048179 (Phosphotyrosine protein) phosphatases II 63-156 2.1e-16 55.4 In-house 33-126 (144) alignment
Range on Protein: 63-156
Range on HMM: 33-126/144.0
VLKVVVKATGQESKLN--HYQWASWPDHGMPDSCDTAHRLLSAVK---KDKKPVIAHCSAGVGRTGTLVLIESMIaalrhPRKQNVKDSFVLLRKDRAR
|. .. .   .. . .  .|.. .||||| ||. .   ..| ...   ....||. |||||||||||||..  |.      .. .... . |.|. |  
vinlteeyepefleregiqylhlpwpDhgvpdllellleflefieealeeggpvlVHCsaGvgRtgtlvaaylmk.....klglsleealalvrsrrpg

0046846 (Phosphotyrosine protein) phosphatases II 51-157 3.1e-16 55.1 In-house 77-155 (176) alignment
Range on Protein: 51-157
Range on HMM: 77-155/176.0
IggkskdkithrvlkvvvkatgqesklnHYQWASWPDHGMPDScDTAHRLLSAVK---KDKKPVIAHCSAGVGRTGTLVLIEsmiaALRHPRKQNVKDSF
|                           .|..  ||||| ||. .  ..|| ...   |...||. |||||.|||||||..      |.. .  .| . .
i...........................qylhlpwpDhgvpdl.elllellefirealkeggpvlVHCsaGigRtgtlvaay....llelekglsveeal

VLLRKDRA-RS
 |.|. |  ..
alvreqRplga

subfamily_Urchin-PTP-6_pd Subfamily Urchin-PTP-6 58-158 3.8e-16 53.3 In-house 157-259 (515) alignment
Range on Protein: 58-158
Range on HMM: 157-259/515.0
KITHRVLKVVvKATGqESKLNHYQWASWPDHGMPDSCDTAHRLLSAVKKDK----KPVIAHCSAGVGRTGTLVLIESMIAALRHPRKQNVKDSFVLLRKD
  . | |.|. |       .  ...  |||.|.|  . .  .|. .|| |.     |.| |||||||||| .. |.|..|  .  |  .| .    .|..
ggikrkltvl.kgdd.srtvtqfhfteWPdkGvpkhtssllklikevkadhgqythpliihcsaGvGrtGvvisidsvvahakttrmvdvfnfvtnirqk

RARSV
|   |
rpylv

subfamily_PTPRA_pd Subfamily PTPRA 72-159 6.9e-16 53.0 In-house 188-279 (330) alignment
Range on Protein: 72-159
Range on HMM: 188-279/330.0
GQESKLNHYQWASWPDHGMPDSCDTAHRLLSAVKKDK----KPVIAHCSAGVGRTGTLVLIESMIAALRHPRKQNVKDSFVLLRKDRARSVR
 ..  .. . . |||| |.|       .|| .||| .     |.. |||||||||||.. ...... ..  || .| .    ||. |.. |.
kksrlvrqfhftswPdvGvPfepiGmlkllkkvkklnqqsagpivvhcsaGvGrtGtfivldavlervkaerkvdvfefvkrlrlqrpqmvq

subfamily_Ptp69D_pd Subfamily Ptp69D 59-156 8e-16 53.0 In-house 178-267 (307) alignment
Range on Protein: 59-156
Range on HMM: 178-267/307.0
IthrvlkvvvkatGQESKLNHYQWASWPDHGMPDSCDTAHRLLSAV----KKDKKPVIAHCSAGVGRTGTLVLIESMIAALRHPRKQNVKDSFVLLRKDR
.             .. |.  |.. .|.|  .|... .  .|.. |    |... |.. ||||||||.|..| ..|..  |.   | .. .    ||..|
v............edsrkvvqyhytgWkDskvPevargllklieqvrelyklnrsPivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqR

AR
  
nl

subfamily_Urchin-PTPRA_pd Subfamily Urchin-PTPRA 65-160 9.8e-16 52.9 In-house 174-276 (319) alignment
Range on Protein: 65-160
Range on HMM: 174-276/319.0
KVVV--KATGQeSKLNHYQWASWPDHGMPDSCDTAHRLLSAV------KKDKKPVIAHCSAGVGRTGTLVLIESMIAALRHPRKQNVKDSFVLLRKDRAR
..    | ...  |.. . .  |||.|.||.     ||.  |      ........ ||||||||||. . .. ..  ... .. .| .    ||..| .
elsedgkekdi.rkitqfhflGwpdvGvpdypsdlmrlvkkvrhltskenhranivvhcsaGvGrtGvyivldvlldrmkeekqvdvynfvrdlrqqrnt

SVRV
 |. 
lvqd

subfamily_Urchin-PTP-8_pd Subfamily Urchin-PTP-8 62-160 1.3e-15 52.7 In-house 135-240 (284) alignment
Range on Protein: 62-160
Range on HMM: 135-240/284.0
RVLKVVV--KATGQeSKLNHYQWASWPDHGMPDSCDTAHRLLSAV------KKDKKPVIAHCSAGVGRTGTLVLIESMIAALRHPRKQNVKDSFVLLRKD
| ...    | ...  |.. . .  |||.|.||.     ||.  |      ........ ||||||||||. . .. ..  ... .. .| .    ||..
rdielsedgkekdi.rkirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrtgvyivldvlldrmkeekqvdvynfvrdlrqq

RARSVRV
| . |. 
rntlvqd

subfamily_PTPRG_pd Subfamily PTPRG 59-154 1.8e-15 51.2 In-house 168-266 (563) alignment
Range on Protein: 59-154
Range on HMM: 168-266/563.0
ITHRVLKVVVKaTGQESKLNHYQWASWPDHGMPDSCDT----AHRLLSAVKKDKKPVIAHCSAGVGRTGTLVLIESMIAALRHPRKQNVKDSFVLLRKDR
| .. ||   . . .| .  .|....||||| |..       ...   | |..  |.. |||||||||||.. .....  ...  . || .    .|  |
iknlklkkkkq.cdteklvrqyhytkWPdhgvPehslpvLifvkkssaankaeaGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqR





subfamily_Cele-PTP-7_pd Subfamily Cele-PTP-7 76-143 2.1e-15 50.9 In-house 189-256 (302) alignment
Range on Protein: 76-143
Range on HMM: 189-256/302.0
KLNHYQWASWPDHGMPDSCDTAHRLLSAVKKDKKPVIAHCSAGVGRTGTLVLIESMIAALRHPRKQNV
 ..  ....||||| |.  .||  .|   .  || |. ||||||||||||| |   |    . .  ..
tvdilafsawpdhGapkeaytaldilkfcesykknvlvhcsaGvGrtGtlvaikyGiqlcskkkvtdl

0044763 (Phosphotyrosine protein) phosphatases II 72-155 2.7e-15 51.9 In-house 75-152 (178) alignment
Range on Protein: 72-155
Range on HMM: 75-152/178.0
GqesklNHYQWASWPDHGMPDS---CDTAHRLLSAVK-KDKKPVIAHCSAGVGRTGTLVLIESMIAAlrhprKQNVKDSFVLLRKDRA
|      .|..  .|||| ||.   .. ..... ..  ....||. ||||||||.||||..  |.       . .. . . |.|. | 
g.....iqylhipipDhgvpdllehflefvefieealdekggpvlVHCsaGvgRsgtlvaaylmkkl.....glsleeaielvrerRp

subfamily_PTPRK_pd Subfamily PTPRK 54-160 6.8e-15 49.7 In-house 150-259 (314) alignment
Range on Protein: 54-160
Range on HMM: 150-259/314.0
KSKDKITHRVLKVVV--KATGQESKLNHYQWASWPDHGMPDSCDTAHRLLSAVKKDK----KPVIAHCSAGVGRTGTLVLIESMIAALRhprKQNVKDSF
. . .. .|...|    ..  .  .....|. .||||..| |  .  .|.  ||| .     ... ||||| ||||| . |....  ..   ...| | |
ellaelvvrifrveklargqeeirevrqfqflgWpdhdvPvsatgllklvrrvkksqeeeaGrivvhCsaGaGrtGtfiaidivldmie...regvvdvf

VLLRKDRARSVRV
   .. |.| | .
navktlrsrkvnm

subfamily_Urchin-PTP-5_pd Subfamily Urchin-PTP-5 60-158 1.4e-14 48.9 In-house 162-267 (297) alignment
Range on Protein: 60-158
Range on HMM: 162-267/297.0
THRVLKVVVKATGQESKLNHYQWASWPDHGMPD--SCDTAHRLLSAVKKDK-----KPVIAHCSAGVGRTGTLVLIESMIAALRHPRKQNVKDSFVLLRK
 .| |.|   .. ..  .. ||. .|||. ..   |  .   |.| |.||       |.. ||.||||||| |. |.|..|  ..  . .. .    ||.
ikrelevtkgkakarrvvkqyqfveWPdkaverkdsassllklisevrkdfsqnaegPllvhclaGvGrtgvlltidsvvaeakrekevdifglvkklrq

DRARSV
.|   |
erpylv

subfamily_Cele-PTP-13_pd Subfamily Cele-PTP-13 68-158 9.2e-14 45.8 In-house 160-252 (281) alignment
Range on Protein: 68-158
Range on HMM: 160-252/281.0
VKATGQESKLNHYQWASWPDHGMPDSCDTAHRLLSAVKKDKKPVIAHCSAGVGRTGTLVLIESMIAALR-HPRKQNVKDSFVLLRK-DRARSV
.   |.   . |. |  |||  .|.| .   ..|  ..    | . ||||||||.|||. .|  . ... |    ..|.    ||   || ||
lsyegetrlithwlwkewpdwqvpessevmlkilrkirarstppvihcsagvgrsgtlmaveialqsihshftlpdikqivshlrvtgraasv

subfamily_Cele-PTP-14_pd Subfamily Cele-PTP-14 43-159 3.6e-13 43.7 In-house 158-274 (310) alignment
Range on Protein: 43-159
Range on HMM: 158-274/310.0
TESCTEIEIGGKSKDKITHRVLKVVVKATGQESKLNHYQWASWPDHGMPDS-CDTA-HRLLSAVKKdkKPVIAHCSAGVGRTGTLVLIESMIAALRHPRK
.||  |.||   .   .   |      |  .| ...  .|  ||| |.||  | |   |||. |..   |.. |||||..|....| ..  |  |..  |
sesseefeicnlavtfvpdnvpvdeqpanlkelrvslikwpnwpdrgvpdekchtvpqrllaqvrh..gpcvvhcsagkdrlyvvvalklkidkldrglk

QNVKDSFVLLRKDRARSVR
 ....    |.|.||  ..
vdaeevktellksraiciq

subfamily_Urchin-PTP-7_pd Subfamily Urchin-PTP-7 51-161 7.5e-13 43.1 In-house 153-265 (315) alignment
Range on Protein: 51-161
Range on HMM: 153-265/315.0
IGGKSKDKITHRVLKVVVKATGQEskLNHYQWASWPDHGMPDSCDTAHRLLSAVKKDK----KPVIAHCSAGVGRTGTLVLIESMIAALRHPRKQNVKDS
.  . ....| | | ||..   .|  .  ....|||| |.| .. .   |   ||. .     ... |||||||||||.. .....  .   .  .| . 
kseevnteytvrtlsvvfgdnire..vvqlhytswpdmgvpkytiplmnlirtvkqhhtnsvgaivvhcsaGvGrtGtfitldavldqaeaenaidvynf

FVLLRKDRARSVRVI
   .|. | . |.|.
itgvrqnrikmvqva

0049772 (Phosphotyrosine protein) phosphatases II 74-143 8.3e-13 44.2 In-house 177-247 (314) alignment
Range on Protein: 74-143
Range on HMM: 177-247/314.0
ESKLNHYQWASWPDHGMPdSCDTAHRLLSAVKK--DKKPVIAHCSAGVGRTGTLVLIESMIAALRHPRKQNV
|    .| .  .||.. | . .   ..| ....  ...||. ||.||.|||||.|..  .. .|. . .. .
erlgikylripvpDgsap.lledfdeflefieeadkggpvlvHCkaGkgRtgtfvvaaylmkllgvsleeal

subfamily_Nvec-PTP-1_pd Subfamily Nvec-PTP-1 68-157 9.4e-13 42.9 In-house 127-222 (239) alignment
Range on Protein: 68-157
Range on HMM: 127-222/239.0
VKATG--QESKLNHYQWASWPDHGMPDSCDTAHRLLSAVKKDK----KPVIAHCSAGVGRTGTLVLIESMiaaLRHPRKQNVKDSFVL---LRKDRARS
.   |  .|  . .|... |||.|.|. . .   |   . ||     .| . ||||||||||....|..|   ||. .||.  | |     .|.|| . 
msqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidam...lrqakkqktvdifnyvkairedrphm

subfamily_Anemone-PTP-1_pd Subfamily Anemone-PTP-1 68-157 9.5e-13 42.9 In-house 128-223 (239) alignment
Range on Protein: 68-157
Range on HMM: 128-223/239.0
VKATG--QESKLNHYQWASWPDHGMPDSCDTAHRLLSAVKKDK----KPVIAHCSAGVGRTGTLVLIESMiaaLRHPRKQNVKDSFVL---LRKDRARS
.   |  .|  . .|... |||.|.|. . .   |   . ||     .| . ||||||||||....|..|   ||. .||.  | |     .|.|| . 
msqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidam...lrqakkqktvdifnyvkairedrphm

subfamily_Anemone-PTP-4_pd Subfamily Anemone-PTP-4 59-145 1.1e-12 42.7 In-house 116-209 (237) alignment
Range on Protein: 59-145
Range on HMM: 116-209/237.0
ITHRVLKVVVKATGQESKLNH-YQWASWPDHGMPDSCDTAHRLLSAV-KK-----DKKPVIAHCSAGVGRTGTLVLIESMIAALRHPRKQNVKD
 | | | .... | .| .| | ||..||||.|.|. . .  |.   . ..     .  | | |||||||||| ...|..|.   .  .  .. .
ytvrslllskrltlkevrlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlrqakekkvvdiyn

subfamily_Sponge-PTP6_pd Subfamily Sponge-PTP6 62-160 1.3e-12 41.9 In-house 159-264 (439) alignment
Range on Protein: 62-160
Range on HMM: 159-264/439.0
RVLKVVVK--ATGQESKLNHYQWASWPDHGMPDSCDTAHRLLSAV-----KKDKKPVIAHCSAGVGRTGTLVLIESMIAALRHPRKQNVKDSFVLLRKDR
| .||. .   | .|  . .... .|||. .|  .     .| |.     |..  ||. |||||||||||.. ..  .  |.   | ..|    .|||.|
rgfkvfnerdttekertvlqfhyiawpdknvpaqashvldflrainsandkeeygpvvvhcsagvGrtGtiialdialeqlklenkvdikgivkvlrkqr

ARSVRV
 . |. 
kqmvqa

subfamily_Sponge-PTP11_pd Subfamily Sponge-PTP11 55-155 4.7e-12 40.4 In-house 157-260 (290) alignment
Range on Protein: 55-155
Range on HMM: 157-260/290.0
SKDKITHRVLKVVVKAT-GQESKLNHYQWASWPDHGMPDSCDTAHRLLS-----AVKKDKKPVIAHCSAGVGRTGTLVLIESMIAALrhpRKQNVKDSFV
. .....| |.|  | . |..... .||  .|...|      |   ...       |. ..... |||..|||..... ..  |      ... | | | 
tlneyierklevknknsagakqsvtqyqitnwdstgkvtnpqtillvieemyktqrkrgntsivvHCSdtvgrsavfcaaattinkc...ktegvidvfq

LLRKDRA
.|.. | 
vlksqRi

subfamily_Urchin-PTP-4_pd Subfamily Urchin-PTP-4 71-156 4.7e-12 40.0 In-house 127-217 (392) alignment
Range on Protein: 71-156
Range on HMM: 127-217/392.0
TGQESK-LNHYQWASWPDHGMPDSCDTAHRLLSAVKKDK----KPVIAHCSAGVGRTGTLVLIESMIAALRHPRKQNVKDSFVLLRKDRAR
 |.. .    .... |||...|    .  ...  || |     .|.| |||||||||| .. |.|..|  .. |  .| .  . .|. |  
kgddartvaqfhftewPdkdvpkhtssllkfikevkadfGqythpliihcsagvgrtgvvisidsvvahakktrmvdvfnfvtnirrkrpy

subfamily_Cele-PTP-9_pd Subfamily Cele-PTP-9 62-142 5.2e-12 40.4 In-house 101-186 (255) alignment
Range on Protein: 62-142
Range on HMM: 101-186/255.0
RVLKVVVKA--TGQESKLNHYQWASWPDHGMPDSCDTAHRLLSAVKKDkKPVIAHCSAGVGRTGTLVLIESMI----AALRHPRKQN
| |... .     .  ...||..  |...  |.       .| .|..  |.|. |||.|.||. ..||.|..      .|.     .
rtleitstlgekkkthtvkhysykGWieknaPelareilnilkvvrds.ksvvvhCstGiGrsaafvlaelvyqkmirsldttetve

subfamily_Sponge-PTP10_pd Subfamily Sponge-PTP10 55-157 1e-11 39.4 In-house 152-257 (287) alignment
Range on Protein: 55-157
Range on HMM: 152-257/287.0
SKDKITHRVLKVVVKA-TGQESKLNHYQWASWPDHG-MPDSCDTA---H-RLLSAVKKDKKPVIAHCSAGVGRTGTLVLIESmiaALRHPRKQNVKDSFV
 ... . | |.|  |  .|.. ... || ..|...| ...        . .  .  |. . ... |||..|||..... ..    .... ... | | | 
vnagyierklevknknkagdkqqvkqyqitnWdstgkvtepqtillvieemyktqrkrgntsivvhCsdtvGrsamfcaaat...tinkckteGviDvfq

LLRKDRARS
.|.. | . 
vlksqriqk

subfamily_Urchin-PTP-3_pd Subfamily Urchin-PTP-3 60-159 1.1e-11 39.5 In-house 163-272 (325) alignment
Range on Protein: 60-159
Range on HMM: 163-272/325.0
THRVLKVVVKATGQESKLNHYQWASWPDHGMPDSCDT----------AHRLLSAVKKDKKPVIAHCSAGVGRTGTLVLIESMIAALRHPRKQNVKDSFVL
 ||||.|     |.   .. .|. ||.| | .    |           .  . |  |   |.. ||||||||||... . |..| . .  . .. ..   
vhrvldvkqvkkGetrsvkqfqlqswddmGvqkrpatlisilqlvkavservtantkastpilvhcsaGvGrtGvfislysalakvieesrvdifgfvkk

LRKDRARSVR
|||||   |.
lrkdrpsmve

subfamily_Cele-PTP-1_pd Subfamily Cele-PTP-1 55-158 2.4e-11 38.3 In-house 139-242 (290) alignment
Range on Protein: 55-158
Range on HMM: 139-242/290.0
SKDKITHRVLKVVVKaTGQESKLNHYQWASWPDHGMPDSCDTAHRLLSAVKKDKKPVIAHCSAGVGRTGTLVLIESMIAALR-HPRKQNVKDSFVLLRKD
 .| . .| | |     ..| ...|..  .| .  ....  |.  |.. ||. | ||| ||  |. |  .|  |.     .     .....|    ||| 
keddvetRelvvkfd.deeeftvtHsllkgWnklnvqedtktllsliqkvkasktpvivHcvdGiSrsAalaaiilgyQkiaetsgsvkledvlkalrkq

RARSV
||  .
ralai

subfamily_ptpA1_pd Subfamily ptpA1 49-141 2.5e-11 38.0 In-house 162-262 (418) alignment
Range on Protein: 49-141
Range on HMM: 162-262/418.0
IEIGGKSKDKITHRVLKVVVkaTGQESKLNHYQWASWPDHGMPDSCDTAHRLLSAVKKD----------KKPVIAHCSAGVGRTGTLVLIESMIAALRHP
.|.    . .|  | ... .   |.   . .||.  |||| .||  .  ..|| .. .           . |.| |||||||||||..    |.  | | 
veviqdpereiitrnirltf..egetrditqyqyegwpdhnipdhtqpfrqllhsitnrqnqiipssdrnvpiivhcsagvgrtgtfctavimmkkldhy

RKQ
 ||
fkq

subfamily_PTPN9_pd Subfamily PTPN9 108-159 3.2e-11 37.8 In-house 223-274 (297) alignment
Range on Protein: 108-159
Range on HMM: 223-274/297.0
KKPVIAHCSAGVGRTGTLVLIESMIAALRHPRKQNVKDSFVLLRKDRARSVR
. |.. |||||.|||||.. ..  .. |..  . .| ..  |||. || |..
gPPivvhcsaGiGrtGtfitldiclsrleevgtvdvvetvkllrtqrafsiq

subfamily_Cele-PTP-15_pd Subfamily Cele-PTP-15 35-143 4.1e-11 37.4 In-house 130-236 (285) alignment
Range on Protein: 35-143
Range on HMM: 130-236/285.0
DLEDHRVYTESCTEIEIGGKSKDKIThrVlKVVVKATGQESKLNHYQWASWPDHGMPDSCDTAHRLLSAVKK---DKKPVIAHCSAGVGRTGTLVLIESm
 .  . .    | |  | |   . .|  |      |. .   .|| |   |||.  |. .     |   |||    .||.  ||||||||| |.| |.  
kfgkyeitlteckeeaiagtilnalt..v.intedasseplymnhvqvpwwpdqlapedarpmielykwvkkvnpkekpicvhcsagvgrtatfvgidy.

iAALRHPRKQNV
 |..|   . |.
.atirimenpni

subfamily_egg_pd Subfamily egg 59-162 1.4e-10 35.3 In-house 159-257 (307) alignment
Range on Protein: 59-162
Range on HMM: 159-257/307.0
ITHrvLKVvVKATGQESKLNHYQWaswpDHGMPDSCDTAHRLLSAVKKDKKPVIAHCSAGVGRTGTLVLIESMIA-ALRHP-RKQNVKDSFVLLRKDRAR
.|.  ||. | .  .|  |.|.|.    |        .  |.|  ...  |||. ..  || ...||| ||  .   || |  |. |. . |.||. |  
vtk..lkl.vGgddeerflehwqg....dvnnssdvysplrvlrklrnlskpvvvqdilGvskaatlvaieiallsllrGpitkslvlravvflrlrrrl

SVRVII
||  ..
svesvl

subfamily_hpo-7_pd Subfamily hpo-7 65-139 6.5e-10 33.3 In-house 113-189 (263) alignment
Range on Protein: 65-139
Range on HMM: 113-189/263.0
KVVVKaTGQESKLNHYQWASWPDHGMPDSCDTAHRLLSAVKKDkKPVIAHCSAGVGRTGTLVLIESMI----AALRHPR
... .   .  ...||..  |...  |       ..| ....  |....|||.|.||.   ...|..      .|.   
stlge.KkkthtvkhysykgWiekndpelareilnilkvarns.kslvvhcstGiGrsaafsvaElvyqkmirsldtts

subfamily_Choan-PTP-4_pd Subfamily Choan-PTP-4 104-160 1e-09 32.7 In-house 224-280 (297) alignment
Range on Protein: 104-160
Range on HMM: 224-280/297.0
VKKDKKPVIAHCSAGVGRTGTLVLIESMIAALRHPRKQNVKDSFVLLRKDRARSVRV
 .  . ... ||||||||.| .|| . ..| ||. |  .|.     ||. ||| |. 
emprnayllvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqt

subfamily_Sponge-PTP1_pd Subfamily Sponge-PTP1 105-157 2.1e-09 31.8 In-house 189-238 (267) alignment
Range on Protein: 105-157
Range on HMM: 189-238/267.0
KKDKKPVIAHCSAGVGRTGTLVLIESMIAALrhpRKQNVKDSFVLLRKDRARS
..  .|.. .||.||||.||.. |.|..  .   ....| | | .||| | . 
engnrPlvvacsdGvGrsGtflvidsqlera...ktegvsdifdflrkirsqr

0038934 (Phosphotyrosine protein) phosphatases II 79-127 2.9e-09 32.4 In-house 81-134 (194) alignment
Range on Protein: 79-127
Range on HMM: 81-134/194.0
HYQWASWPDHGMPDSCDTAHRLLSAV-----KKDKKPVIAHCSAGVGRTGTLVL
.|    .||.| . | .. .| |..|     .. .. |  || ||.||||||| 
eylklpfpddgtvPsleillrfldlvdeflnedpggvvaVHCkaGlgRtGtlva

subfamily_Urchin-PTP-2_pd Subfamily Urchin-PTP-2 75-156 3e-09 30.7 In-house 89-175 (440) alignment
Range on Protein: 75-156
Range on HMM: 89-175/440.0
SKLNHYQWASWPDHGMPDSCDTAHRLLSAVKK-----DKKPVIAHCSAGVGRTGTLVLIESMIAALRHPRKQNVKDSFVLLRKDRAR
  |..|.. .|||.|.|  .    ...  |..      . |.. |||||.|||| .. ..|..   ..  . ..      .|..| .
rtlkqyhyqgwpdkgvpkfagpvlkmiqdvnesqekagngpllvhcsagagrtgviiavdsilreakrsdqidifsfinsmrnnrpq

subfamily_Fungi-PTP2_pd Subfamily Fungi-PTP2 104-153 4.5e-09 30.1 In-house 261-310 (349) alignment
Range on Protein: 104-153
Range on HMM: 261-310/349.0
VKKDKKPVIAHCSAGVGRTGTLVLIESMIAALRHPRKQNVKDSFVLLRKD
 ...  ... ||||| ||||.|| ...... |  .... .|  .  |.||
dtdqlstllvhcsaGcGrtGvlvtldlllsileplqnesnkiklqallkD

subfamily_Fungi-PTP1_pd Subfamily Fungi-PTP1 103-134 5.3e-09 30.2 In-house 257-288 (350) alignment
Range on Protein: 103-134
Range on HMM: 257-288/350.0
AVKKDKKPVIAHCSAGVGRTGTLVLIESMIAA
  ..  .|.. ||||||||||||| ..|..  
ldnarsspilvhCsaGvGrtGtlvtlDsllsd

subfamily_CG42327_pd Subfamily CG42327 102-160 7.7e-09 29.6 In-house 241-300 (319) alignment
Range on Protein: 102-160
Range on HMM: 241-300/319.0
SAVKKDKKPVIAHCSAGVGRTGTLVLIESMIAALRHP-RKQNVKDSFVLLRKDRARSVRV
|. .... |.. ||| ||||||...  .  |  | .. |  .. .    .|.|||..|. 
sgtresqGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavlt

subfamily_PTPN9_pd Subfamily PTPN9 51-106 1.1e-08 29.4 In-house 149-204 (297) alignment
Range on Protein: 51-106
Range on HMM: 149-204/297.0
IGGKSKDKITHRVLKVVVKATGQESKLNHYQWASWPDHGMPDSCDTAHRLLSAVKK
.  ..... ..|||..    |... |. |.|  ||||.|.|.|. .   .|..|..
veveeeedykvrvleiknvkteesrkvthfqflsWPdyGvPssaaslldvlekvre

PTPc_motif_SM00404 71-132 1.1e-08 30.0 In-house 43-104 (140) alignment
Range on Protein: 71-132
Range on HMM: 43-104/140.0
TGQESKLNHYQWASWPDHGMPDSCDTAHRLLSAVKKDKKPVIAHCSAGVGRTGTLVLIESMI
  .. .. ...        . .  | . . .....|... |. || ||| |..||.. . | 
ensgfqilqiplddnekdklskyldkvldfienaekkggkvlVHCqaGvSRSatliiaYlmr

subfamily_PTPRN_pd Subfamily PTPRN 75-156 3.9e-08 27.3 In-house 187-273 (297) alignment
Range on Protein: 75-156
Range on HMM: 187-273/297.0
SKLNHYQWASWPDHGMPDSCDTAHRLLSAVKK----DKKPVIAHCSAGVGRTGTLVLIESMIAALRHPR-KQNVKDSFVLLRKDRAR
  .  . . |||..|.| |  .   .   | |       |.. |||.|.||||. .||. ... | .   . ..  .   || .|. 
rtvtqfhflswpeegvPasaksllefrrkvnksyrGrscpivvhcsdGaGrtGvyilidlvlnrllkGvkeidiaatlehlrdqrpg

subfamily_Choan-PTP-3_pd Subfamily Choan-PTP-3 54-160 4.7e-08 27.1 In-house 148-262 (287) alignment
Range on Protein: 54-160
Range on HMM: 148-262/287.0
KSKDkITHRVLKVVvKATGQE-SKLNHYQWASWPDHGMPDSCDTAHRLLSAV---------KKDKKPVIAHCSAGVGRTGTLVLIESMIAALRHPRKQNV
|. .  . | |... .. ..|   .. ... ||||.... ..    |.   |          ..  |.. |...|.||.|.|. .  ..  |    . .|
kePe.ygvralrli.dletrearvvkqldllswPdkvlaPtavglirfvldvkqhielardasevGPlvvhddvGiGrsGillatlvlvsrledlGrvdv

KDSFVLLRKDRARSVRV
    . ||. ||  |. 
aavvirlreyraalvqa

subfamily_Nvec-PTP-3_pd Subfamily Nvec-PTP-3 45-154 5.5e-08 27.2 In-house 64-179 (198) alignment
Range on Protein: 45-154
Range on HMM: 64-179/198.0
SCTEIEIGGKSKDKITHRVLKVVVKATGQESKLNHYQWASWPDHGMPDSCD-----TAHRLLSAVKKD--KKPVIAHCSAGVGRTGTLVLIESMIAALRh
| |   |  |.   ||  .|   . |     .. |||..|| ..  |. .       | | .|   ..    ||| ||| | | || .| ..  . .   
svttktittkpdytitaliltnnttappstreishyqftswkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrshe.

PRKQNVKDSFVLLRKDR
  |  | | | . .. |
esktsvvdlfevakrlr

subfamily_Anemone-PTP-3_pd Subfamily Anemone-PTP-3 45-154 5.7e-08 27.2 In-house 65-180 (199) alignment
Range on Protein: 45-154
Range on HMM: 65-180/199.0
SCTEIEIGGKSKDKITHRVLKVVVKATGQESKLNHYQWASWPDHGMPDSCD-----TAHRLLSAVKKD--KKPVIAHCSAGVGRTGTLVLIESMIAALRh
| |   |  |.   ||  .|   . |     .. |||..|| ..  |. .       | | .|   ..    ||| ||| | | || .| ..  . .   
svttktittkpdytitaliltnnttappstreishyqftswkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrshe.

PRKQNVKDSFVLLRKDR
  |  | | | . .. |
esktsvvdlfevakrlr

subfamily_Sponge-PTP5_pd Subfamily Sponge-PTP5 60-149 8.3e-08 26.4 In-house 146-237 (283) alignment
Range on Protein: 60-149
Range on HMM: 146-237/283.0
THRVLKVVVKATGQES-KLNHYQWASWPDHGMPDSCDTA---HRLLSAVKK-DKKPVIAHCSAGVGRTGTLVlieSMIAALRHPRKQNVKDSFVL
. . | . |... ...  | |||   | . |     ..     .. |  ..  | |.. |||.|.|||....   .. |.. . . . | | |  
iikelllrvnssakstlllahyqvidWleygeqaiinslvkfnkvislqteskkgPivvhCstgiGrtavfi...aasasvkdaltesvvdvfav

subfamily_Sponge-PTP9_pd Subfamily Sponge-PTP9 49-128 9.4e-08 26.1 In-house 164-246 (301) alignment
Range on Protein: 49-128
Range on HMM: 164-246/301.0
IEIGGKSKDKITHRVLKVVVKAtgQESKLNHYQWASWPDHGMPDSCDTAHRLL-----SAVKKDKKPVIAHCSAGVGRTGTLVLI
. |   |... ..| .||  .   .  ..  .| ..||..|.     |  . .        | .. ||. |||..|.|.|. . .
vkiqdgsnngyierkfkvksdk..sswdvlqlqvtdWpqdGvvreprtvLqviddvihrqqkigggpvvVHCSdtVsrsGvYcsv

PTEN_1 80-154 1.4e-07 26.5 In-house 95-171 (196) alignment
Range on Protein: 80-154
Range on HMM: 95-171/196.0
YQ--WASWPDHGMP---DSCDTAHRLLSAVKK--DKKPVIAHCSAGVGRTGTLVliesmIAALRHPRKQNVKDSFVLLRKDR
..    ...||| |     .| . .. .....  ... |. || ||.||.||.|     .| | . .| .... . |.|. |
veylhfpieDhgapslselfdicksfiewllsdpngnvVlVHCkaGlgRsGtvv.....aayLmykgkltadeAlelvrekR

DSPc Dual specificity phosphatase, catalytic domain 71-127 2.1e-07 25.9 Pfam-A 36-92 (133) alignment
Range on Protein: 71-127
Range on HMM: 36-92/133.0
TGQESKLNHYQWASWPDHGMPDSCDTAHRLLSAVKKDKKPVIAHCSAGVGRTGTLVL
. .| .  ...     .  . .  . | . ........| |. || ||. |..||..
kkseieylripvedetetkiskeleeavefiekaeqkgkkvlVHCqaGisRSatlii

DSPc Dual specificity phosphatase, catalytic domain 71-127 2.1e-07 25.9 In-house 36-92 (133) alignment
Range on Protein: 71-127
Range on HMM: 36-92/133.0
TGQESKLNHYQWASWPDHGMPDSCDTAHRLLSAVKKDKKPVIAHCSAGVGRTGTLVL
. .| .  ...     .  . .  . | . ........| |. || ||. |..||..
kkseieylripvedetetkiskeleeavefiekaeqkgkkvlVHCqaGisRSatlii

subfamily_PTEN_pd Subfamily PTEN 93-159 1.3e-06 23.5 In-house 101-164 (184) alignment
Range on Protein: 93-159
Range on HMM: 101-164/184.0
SCDTAHRLLSAvkKDKKPVIAHCSAGVGRTGTLVLiESMIAALRHPRKQNVKDSFVLLRKDRARSVR
 ...... |..  ..|. |. || || ||||.|.    .. .|  ........ |   |   ...| 
ivediekwlee..dkknvvvvHCkaGkGRtGvliv.ayllkslllekaeealelfaeaRtknkkgvt

Y_phosphatase3 Tyrosine phosphatase family 94-128 2.3e-06 22.7 Pfam-A 110-144 (164) alignment
Range on Protein: 94-128
Range on HMM: 110-144/164.0
CDTAHRLLSAVKKDKKPVIAHCSAGVGRTGTLVLI
 .. ...|.|. ....||. ||.||  ||| .. .
kkayrkvlealaeeegpvlfHCtaGKDRTGvvaal

0048567 (Phosphotyrosine protein) phosphatases II 87-127 6.3e-06 20.7 In-house 47-96 (157) alignment
Range on Protein: 87-127
Range on HMM: 47-96/157.0
DHGmPDS-------CDTAHRLLSAVKKDKKPVIAHCSAGV---GRTGTLVL
|.| | .       .  ....|. ... .|... ||.||    |||.||. 
dfG.PlnlailyrFilklnkflkilelagkaiavhckaglkkrgrtatLig

subfamily_CG7180_pd Subfamily CG7180 77-156 9.4e-06 19.5 In-house 182-271 (296) alignment
Range on Protein: 77-156
Range on HMM: 182-271/296.0
LNHYQWASWPD-HGMPDS----CDTAHRLLSAVKK-----DKKPVIAHCSAGVGRTGTLVLIESMIAALRHPRKQNVKDSFVLLRKDRAR
. ..|.  |.  . .| |     .  .|  . ..|     ...||. ..| |..|.|  . |.  .  ...  . .| .    ||..| .
vklfqlteWeledkvPlstnalielrrrvrlwrekvdedpeegPvvvvssdGasRsGvylaidanlelvekeeevdvFeavktlrrsRpq