Gene F20B6.6 in Caenorhabditis elegans

Synonym: CELE_F20B6.6, F20B6.6

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family PTP
Subfamily CelePTP-sf11
Protein sequence
ID Type Fasta BLAST phosphatome Note
CeleP062_AA protein Get Run
CeleP062_AA_48-135 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_Cele-PTP-11_pd Subfamily Cele-PTP-11 51-135 1.3e-61 203.0 In-house 1-85 (312) alignment 
Range on Protein: 51-135
Range on HMM: 1-85/312.0
QRAEMIKKWASAVMMSTPQQLTKEYKAVGNIFPDSECTAFLKFKDLNRYPNIQCWDRGRFTLAGDENFYIHANFVKICTKPEREI
|||||||||||||||||||||||||||||||..|||||||||||||||||||||||||||||||||||||||||||||||||| .
qraemikkwasavmmstpqqltkeykavgnivsdsectaflkfkdlnrypniqcwdrgrftlagdenfyihanfvkictkperfv
0050432 (Phosphotyrosine protein) phosphatases II 49-129 2.5e-14 48.8 In-house 25-105 (308) alignment 
Range on Protein: 49-129
Range on HMM: 25-105/308.0
KEQRAEMIKKWASavmMSTPQQLTKEYKAVGNIFPDSE--CTAFLKFKDLNRYPNIQCWDRGRFTLaGDENFYIHANFVKIC--T
|    ...|.. .   .  ...| .|.... ...|. |  .... . ||.|||..| ..|. |  | .... ||.|..|...   
klsvldllkllek...aldlglleeefeellsvkplleysvallpenkdkNrykdilpydhsRVkl.degsdYInAsyvdgyssk
0036941 (Phosphotyrosine protein) phosphatases II 54-135 6.6e-13 44.1 In-house 5-81 (297) alignment 
Range on Protein: 54-135
Range on HMM: 5-81/297.0
EMIKKWASAVMMSTPQQLTKEYKavgniFPDSECTAFLKFKDLNRYPNIQCWDRGRFTLAGDENFYIHANFVKICTKPEREI
 ..|.. .| ...  ..|.. ..      .. ....... ...|||..| ..|. |  | .... ||.|..|...  . . |
llekllflalllkefeellplll.....lgslsvallpenleknRykdilpydhtRVklddegsdYinAsyvdgydlkrkfI
0047943 (Phosphotyrosine protein) phosphatases II 69-135 6.7e-13 44.2 In-house 12-80 (273) alignment 
Range on Protein: 69-135
Range on HMM: 12-80/273.0
QQLTKEYKAVGNIFPDSE--CTAFLKFKDLNRYPNIQCWDRGRFTLAGDENFYIHANFVKICTKPEREI
..| .|.... ...|. .  .... . ||.|||..| ..|. |  | .... ||.|..|. . .. . |
tllleefelllslkplltysvallpenkdknrykdilpydhsrvklgdggsdyinAsyvdgynlkrkfi
0039614 (Phosphotyrosine protein) phosphatases II 63-131 8e-13 44.0 In-house 26-100 (297) alignment 
Range on Protein: 63-131
Range on HMM: 26-100/297.0
VMMSTPQQLTKEYKAVGNIFPDSECTAFLKFKDLNRYPNIQCWDRGRFTLAGDENF-----YIHANFVKICTK-P
  .. ...| .|.. . ...|| ..... . ||.|||..| ..|. |  | . ...     ||.|..|.   . .
ekansktllllefeellslkpdysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydllt
0045450 (Phosphotyrosine protein) phosphatases II 54-127 3.2e-12 42.3 In-house 12-94 (307) alignment 
Range on Protein: 54-127
Range on HMM: 12-94/307.0
EMIKKWASAVMMSTPQQLTKEYKAVGNIFP----DSECTAFLKFKDLNRYPNIQCWDRGRFTLAG-----DENFYIHANFVKI
... ..    . . .. | ||.. . .. .    . ....... ||.|||..| ..|. |  |       ... ||.|..|..
lkllllvllllldfltgllkefekllsvtvfllgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrv
0040438 (Phosphotyrosine protein) phosphatases II 62-135 4.6e-12 41.3 In-house 11-89 (317) alignment 
Range on Protein: 62-135
Range on HMM: 11-89/317.0
AVMMSTPQQLTKEYKAVGNIFPD-SECTAFLKFKDLNRYPNIQCWDRGRFTLAGDE----NFYIHANFVKICTKPEREI
 ...|  ..| .|.. . ....|  ....... ||.||||.| ..|. |  |  ..    . ||.|..|..  .. . |
dllksdftalleefedllslkldtysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfI
0051299 (Phosphotyrosine protein) phosphatases II 53-135 5e-12 41.3 In-house 7-95 (288) alignment 
Range on Protein: 53-135
Range on HMM: 7-95/288.0
AEMIKKWASAVMMSTPQQLTKEYKAVGNIFPDSE--CTAFLKFKDLNRYPNIQCWDRGRFTLAG----DENFYIHANFVKICTKPEREI
.| . |.  ..... . .| .|.... ...|| .  .... . .. |||..| ..|. |  |      ... ||.|...... .. . |
veellklvlkllangltglleefeellsllpdltlsaallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyidgynlkrkfI
0046845 (Phosphotyrosine protein) phosphatases II 71-128 3e-11 38.7 In-house 2-68 (284) alignment 
Range on Protein: 71-128
Range on HMM: 2-68/284.0
LTKEYKAVGNIFP----DSECTAFLKFKDLNRYPNIQCWDRGRFTLAG-----DENFYIHANFVKIC
| .|.... ....    . ....... ...|||..| ..|. |  |       ... ||.|..|. .
leeefeellsltvklllslsvallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgy
subfamily_Cele-PTP-8_pd Subfamily Cele-PTP-8 52-133 3.2e-11 37.8 In-house 2-83 (288) alignment 
Range on Protein: 52-133
Range on HMM: 2-83/288.0
RAEMIKKWASAVMMSTPQQLTKEYKAVGNIFPDSECTAFLKFKDLNRYPNIQCWDRGRFTLAGDENFYIHANFVKICTKPER
. |.|  |   |.  . . | |||.   |  .    ..|..    .|| |. . |  |  |  | .|||.|| |     ..|
kkevinawirlvlqiaveglkkeyrdspneasidiidsfianptrdryenlprcditrvklsddpdfyiaanvvssakykrr
subfamily_Cele-PTP-6_pd Subfamily Cele-PTP-6 55-135 7.6e-11 36.6 In-house 2-85 (307) alignment 
Range on Protein: 55-135
Range on HMM: 2-85/307.0
MIKKWASAVMMSTPQQLTKEYKAVGNIFPD-SECTAFLKFKDLNRYPNIQCWDRGRFTL--AGDENFYIHANFVKICTKPEREI
..| |    .    |.|. |.. . .  |.     ||    | ||| ...| |.||  .   |    |||||.. |..|| . |
vvkpwvqrtldkgvqalvdefrvlakktpegvtveafsantdknryqdvkcqdkgrivvkfdglasdyihanylgiaikpkkfi
0043336 (Phosphotyrosine protein) phosphatases II 73-135 2.8e-10 35.6 In-house 24-91 (278) alignment 
Range on Protein: 73-135
Range on HMM: 24-91/278.0
KEY-------KavgnifPDSECTAFLKFKDLNRYPNIQCWDRGRFTLAGDE----NFYIHANFVKICTKPEREI
.|.       .      .. ....... ||.|||..| ..|. |  |  ..    . ||.|..|.   .|.. |
lefeellsfkl......dtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfi
0042113 (Phosphotyrosine protein) phosphatases II 86-135 1.5e-08 29.9 In-house 2-55 (245) alignment 
Range on Protein: 86-135
Range on HMM: 2-55/245.0
ECTAFLKFKDLNRYPNIQCWDRGRFTLAGDE----NFYIHANFVKICTKPEREI
....... ||.|||..| ..|. |. |  |.    . ||.|..|. .  ... |
svallpenkdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpkfi
0045098 (Phosphotyrosine protein) phosphatases II 71-131 1.9e-08 29.6 In-house 11-63 (278) alignment 
Range on Protein: 71-131
Range on HMM: 11-63/278.0
LTKEYKAVGNIFPDSECTAFLKFKDLNRYPNIQCWDRGRFTlagDenfYIHANFVKICtkP
|  |.. . .|. . ..  .|. .|.|||..|...|. |     |   ||.|......  |
lefefllllgipseitpalylgnldknRykdilpydhsrVk...d...YINAsyidgy..p
0040439 (Phosphotyrosine protein) phosphatases II 84-135 4.2e-08 28.6 In-house 2-57 (249) alignment 
Range on Protein: 84-135
Range on HMM: 2-57/249.0
DSECTAFLKFKDLNRYPNIQCWDRGRFTLAGDE----NFYIHANFVKICTKPEREI
. ... ... ||.||||.| ..|. |. |   .    . ||.|.... .  . | |
eysvallpenkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrrfi
subfamily_Cele-PTP-18_pd Subfamily Cele-PTP-18 49-135 8.4e-08 26.3 In-house 2-91 (305) alignment 
Range on Protein: 49-135
Range on HMM: 2-91/305.0
KEQRAEMIKKWASAVMMSTPQQLTKEYKAVGNIFPDSECTAFLKFKD--LNRYPNIQCWDRGRFTLAGDE-NFYIHANFVKICTKPEREI
| |.   | |.   ..  .|. | .|..|.  .       || . ..   ||| .. | |. |  | |     |||||.|   |.|.| |
kkqqkkqilkfvkrtlekgpaglraefvamkrfndfekmkafkeaqeagknrykdvgcldnnrvklegpwpheyihanyvstptnpkrfi
DSPc_SM00195 76-135 2e-07 26.0 In-house 7-72 (263) alignment 
Range on Protein: 76-135
Range on HMM: 7-72/263.0
KAVGNIFP--DSECTAFLKFKDLNRYPNIQCWDRGRFTLAGDE----NFYIHANFVKICTKPEREI
. . .  .  ....... | |. ||| || . |. |  |  .|    . ||.||..|. .|... |
ekleestspketteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyI
PTPc_SM00194 76-135 2e-07 26.0 In-house 7-72 (263) alignment 
Range on Protein: 76-135
Range on HMM: 7-72/263.0
KAVGNIFP--DSECTAFLKFKDLNRYPNIQCWDRGRFTLAGDE----NFYIHANFVKICTKPEREI
. . .  .  ....... | |. ||| || . |. |  |  .|    . ||.||..|. .|... |
ekleestspketteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyI
0037934 (Phosphotyrosine protein) phosphatases II 87-128 2.1e-07 26.2 In-house 4-43 (243) alignment 
Range on Protein: 87-128
Range on HMM: 4-43/243.0
CTAFLKFKDLNRYPNIQCWDRGRFTLAGdeNFYIHANFVKIC
.  ..  .. |||..| ..|..|  | |  . ||.||.... 
iallpenlsknrysdilpydhsrvkleg..sdyinanliyvt
subfamily_PTPN13_pd Subfamily PTPN13 69-130 8.7e-07 23.5 In-house 11-73 (273) alignment 
Range on Protein: 69-130
Range on HMM: 11-73/273.0
QQLTKEYKAVGNIFPDSECTAFLK--FKDLNRYPNIQCWDRGRFTLAGDENfYIHANFVKICTK
|| ..|.| . .. |  .|.   |   || ||| |.  .|. | .| .. . || |...|.   
qqPaeefkelrelkpldtcevgkkkenkdknryrnvlPydetrvklgdegg.yinaslikvpvg
subfamily_Cele-PTP-15_pd Subfamily Cele-PTP-15 74-131 1.4e-06 22.5 In-house 16-73 (285) alignment 
Range on Protein: 74-131
Range on HMM: 16-73/285.0
EYKAVGNIFPDSECTAFLKFKDLNRYPNIQCWDRGRFTLAGDENFYIHANFVKICTKP
. |  | . |.   ||.    ||||| ...| .  |  |   .  ||||.....  | 
qdkikgymppnctytayeanpdlnryadvrcieetrvvlknhdrdyihaswmrmpgkd
subfamily_Cele-PTP-20_pd Subfamily Cele-PTP-20 52-127 1.8e-06 21.8 In-house 10-91 (290) alignment 
Range on Protein: 52-127
Range on HMM: 10-91/290.0
RAEMIKKWASAVMMSTPQQLTKEYKAVGNIF-PDS--ECTAFLKFK--DLNRYPNIQCWDRGRFTLA-GDENFYIHANFVKI
..| ..|.|| |.  ....|.|||      . |    |   | |      ||| .. | |. |  |  | .  |.|||.|| 
qteafekfasdvvkknvdelakeyleklkpylpvqylerkifdkntefkknrykdvvcndktrvilkdGydGdyvhanyvkG
Y_phosphatase Protein-tyrosine phosphatase 95-133 4.1e-06 21.8 Pfam-A 3-43 (235) alignment 
Range on Protein: 95-133
Range on HMM: 3-43/235.0
DLNRYPNIQCWDRGRFTL--AGDENFYIHANFVKICTKPER
. |||..| . |. |  |   .... ||.||.||  .....
kknRykdilpydktrvklkgsegpsdYInAnyvkgykekkk
Y_phosphatase Protein-tyrosine phosphatase 95-133 4.1e-06 21.8 In-house 3-43 (235) alignment 
Range on Protein: 95-133
Range on HMM: 3-43/235.0
DLNRYPNIQCWDRGRFTL--AGDENFYIHANFVKICTKPER
. |||..| . |. |  |   .... ||.||.||  .....
kknRykdilpydktrvklkgsegpsdYInAnyvkgykekkk
subfamily_Cele-PTP-4_pd Subfamily Cele-PTP-4 60-128 4.3e-06 20.4 In-house 16-86 (302) alignment 
Range on Protein: 60-128
Range on HMM: 16-86/302.0
ASAVMMS-TPQQLTKEYKAVGNIFPDS-ECTAFLKFKDLNRYPNIQCWDRGRFTLAGDENFYIHANFVKIC
| ... | . ....||.|.. ..  |  .|.|| |  . |. ..... |  .  |.. ...|..|  |.. 
akklvksldtaevkkefkkidtmkvdlekCkafkknlkknqsedvpildsnlvkleaepdsyvnaskvevP