Gene F26A3.4 in Caenorhabditis elegans

Synonym: CELE_F26A3.4, F26A3.4

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family DSP
Subfamily DSP14
Protein sequence
ID Type Fasta BLAST phosphatome Note
CeleP070_AA protein Get Run
CeleP070_AA_11-156 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_DSP14_pd Subfamily DSP14 9-163 8.7e-68 221.2 In-house 2-154 (157) alignment 
Range on Protein: 9-163
Range on HMM: 2-154/157.0
PEYAAMSEIVPGLFICGVSALSKDEMKKHKITHIINATTEVPNlRSLGDIQRTKLWLEDTPQTYIYPHLELQSDQIQALIADGGKVLVHCVAGVSRSASI
||.||.|.|.| ||..||.||||...||.|||.|||.|.|.|| ..| ||.|.|...||.|......|.. ..|.|... ..|||.|||||||||||||.
pelaalsqitpsLflsgvaalskellkkkkitliinvtvelpn.tklkdiervkvpveDnpeaklakhfdevadkieevkkkggktlvhCvaGvSRSAsl

CLAFLLKYRCRNLREAYHLMKSKRSMVRPNLGFWRQLIAYEQNVKENAgSVRLVR
|||.|.||....|||||.|.||.|...|||.|||.|||.||...|... ||..| 
claylmkyeklsLreayklvksaRpiirPNvGFwkqlidyEkklkgks.svkmvd
PTPc_motif_SM00404 14-150 4.1e-40 131.9 In-house 2-139 (140) alignment 
Range on Protein: 14-150
Range on HMM: 2-139/140.0
MSEIVPGLFICGVSALS-KDEMKKHKITHIINATTEVPNLRSLGDIQRTKLWLEDTPQTYIYPHLELQSDQIQALIADGGKVLVHCVAGVSRSASICLAF
.|.| |.|.... |. . .. .||..|||.||.|.||.. ..  ..|. ...|.|. .. . ..|.   | |.. ...|||||||| |||||||....|.
psrilphlylgskskaqnpallkklgithvinvteevsltkensgfqilqiplddnekdklskyldkvldfienaekkggkvlVHCqaGvSRSatliiaY

LLKYRCRNLREAYHLMKSKRSMVRPNLGFWRQLIAYEQ
|..||  .|.|||...|..|....|||.|.|||| ||.
lmryrqlslaeayefvkerRpiispnlnfvrqLieyek
DSPc Dual specificity phosphatase, catalytic domain 21-150 2.1e-39 129.4 Pfam-A 1-132 (133) alignment 
Range on Protein: 21-150
Range on HMM: 1-132/133.0
LFICGVSALSKDEMKKHKITHIINATTEVPN--LRSLGDIQRTKLWLEDTPQTYIYPHLELQSDQIQALIADGGKVLVHCVAGVSRSASICLAFLLKYRC
|.... |. |.. ..|..||..||.|.||||  ... ..|.......||. .| | ..||  .. |......|.|||||| ||.||||....|.|.|...
lylgskstaslalleklgitlvinvtkevpnnnaikkseieylripvedetetkiskeleeavefiekaeqkgkkvlVHCqaGisRSatliiaYlmktkn

RNLREAYHLMKSKRSMVRPNLGFWRQLIAYEQ
 .|.|||...|..||...|| ||.|||..||.
lslneAyefvkerrskispnagflrqLleyer
DSPc Dual specificity phosphatase, catalytic domain 21-150 2.1e-39 129.4 In-house 1-132 (133) alignment 
Range on Protein: 21-150
Range on HMM: 1-132/133.0
LFICGVSALSKDEMKKHKITHIINATTEVPN--LRSLGDIQRTKLWLEDTPQTYIYPHLELQSDQIQALIADGGKVLVHCVAGVSRSASICLAFLLKYRC
|.... |. |.. ..|..||..||.|.||||  ... ..|.......||. .| | ..||  .. |......|.|||||| ||.||||....|.|.|...
lylgskstaslalleklgitlvinvtkevpnnnaikkseieylripvedetetkiskeleeavefiekaeqkgkkvlVHCqaGisRSatliiaYlmktkn

RNLREAYHLMKSKRSMVRPNLGFWRQLIAYEQ
 .|.|||...|..||...|| ||.|||..||.
lslneAyefvkerrskispnagflrqLleyer
subfamily_DSP1_pd Subfamily DSP1 9-154 1.4e-36 120.0 In-house 13-158 (163) alignment 
Range on Protein: 9-154
Range on HMM: 13-158/163.0
PEYAAMSEIVPGLFICGVSALSK-DEMKKHKITHIINATTEVPNLRSLgDIQRTKLWLEDTPQTYIYPHLELQSDQIQALIADGGKVLVHCVAGVSRSAS
. |  . .|.. |.. . .  |. . .|...||.|.|...|..|       .  || |||.|.  |. ..|   . |.. .. .||||.|| ||.|||..
klydPvekildfLylGsetvasnleiLkslgitailnvskeldnvfed.lfeYkklkleDspkadislvfeeviefidevkkknGkvlihCqaGisRsst

ICLAFLLKYRCRNLREAYHLMKSKRSMVRPNLGFWRQLIAYEQNVKE
.|||.|.| .  .| ||....|..||...||.|| .||. ||.... 
lclaylmktkrvsleeafdfvkqrRsiisPnagFvlqLlnyekklll
subfamily_DSP19_pd Subfamily DSP19 13-152 5.4e-35 115.0 In-house 11-150 (152) alignment 
Range on Protein: 13-152
Range on HMM: 11-150/152.0
AMSEIVPGLFICGVSA-LSKDEMKKHKITHIINATTEVPNLrSLGDIQRTKLWLEDTPQTYIYPHLELQSDQIQALIADGGKVLVHCVAGVSRSASICLA
 ..|. | |..  ...  .|...|..|||||.| .|.|||.    |.. ... . |.|.| .  .|.   | |.      | ||||| ||||||||. .|
evgeveprlylgsqdvaadkeilkekkitHilnvatgvpnv.fpkdftylsieilDlpetdllsylkealdFieearskdgavlvHCnAGvSRsasvvia

FLLKYRCRNLREAYHLMKSKRSMVRPNLGFWRQLIAYEQNV
.|.| .  .|.||..|....|  ..|| ||..|| .||...
ylmkkeelsleealelvrearpcikPneGFikqLkeyeael
subfamily_DSP10_pd Subfamily DSP10 11-155 7.2e-35 114.2 In-house 11-156 (159) alignment 
Range on Protein: 11-155
Range on HMM: 11-156/159.0
YAAMSEIVPGLFIC-GVSALSKDEMKKHKITHIINATTEVPNLRSLGDIQRTKLWLEDTPQTYIYPHLELQSDQIQALIADGGKVLVHCVAGVSRSASIC
 | .|...| ||.  .. | ..| .....||...| ||.|||  .  ...  .. ..|| .  .  . |   . |.     | .||||| ||.||||.. 
tapasqvlpfLflGsekdaadldaldrlnitavlnvttsvPnefeeealkYkripvsDtskqnlkqyfeealefieearkkgsrvLvhCqaGisrsatvv

LAFLLKYRCRNLREAYHLMKSKRSMVRPNLGFWRQLIAYEQNVKEN
.|.|.|..  .|..||...|.||... |||.|  ||. .|......
iaYlmkhlnlslndaykfvkekrpiisPnLnfmGqLlefekelnks
0044763 (Phosphotyrosine protein) phosphatases II 9-153 1.9e-34 114.2 In-house 18-171 (178) alignment 
Range on Protein: 9-153
Range on HMM: 18-171/178.0
PEYAAMSEIVPGLFICGVSALS-KDEMKKHKITHIINATTEVPNL------RSL--GDIQRTKLWLEDTPQTYIYPHLELQSDQIQALI-ADGGKVLVHC
 .|  .|||.|||....  . . .. .|...||||.| |.|...         .   .||  .. ..| . . .. |..   . |....  .||.|||||
sdyinaseilpglylgslppaddlellkelgithivnlteelelgflkcdpywpeeagiqylhipipDhgvpdllehflefvefieealdekggpvlVHC

VAGVSRSASICLAFLLKYRCRNLREAYHLMKSKRSmVRPNLGFWRQLIAYEQNVK
 |||.||.....|.|.|..  .| ||..|....|. . || |..|||. .|. ..
saGvgRsgtlvaaylmkklglsleeaielvrerRp.ivpnpgqlrqLyefelrll
subfamily_DSP12_pd Subfamily DSP12 14-151 4.5e-32 105.6 In-house 2-142 (155) alignment 
Range on Protein: 14-151
Range on HMM: 2-142/155.0
MSEIVPGLFICGVSALSK-DEMKKHKITHIINATTE-VPN-LRSLGDIQRTKLWLEDTPQTYIYPHLELQSDQIQALIADGGKVLVHCVAGVSRSASICL
.|.| |||.. |..|. . . .|. ||||..  ..| .|.   . | ... .. . |.|.. |  ||.   | |.  ....|.||||| ||||||..|..
vsrilpglylggleavqeeellkelkithvlsvikeelpehklkkgkvstkfiqilDepeediLshldeavdFieealeeegavlvHCqagvSRSvtivi

AFLLKYRCRNLREAYHLMKSKRSMVRPNLGFWRQLIAYEQN
|.|.|.   .| .|..|.|.|.. ..|| || .||  .|. 
AYlmkkeklslekAlklvkekkpeiepNegFleQLklfekm
subfamily_MKPLT_pd Subfamily MKPLT 30-150 6.1e-30 97.9 In-house 39-158 (164) alignment 
Range on Protein: 30-150
Range on HMM: 39-158/164.0
SKDEMKKHKITHIINATTEVPNLRSlGDIQRTKLWLEDTPQTYIYPHLELQSDQIQALIADGGKVLVHCVAGVSRSASICLAFLLKYRCRNLREAYHLMK
..  .|. |||||.| ..|  .  .   ..  .. .||.... . ..||  .. .   |  ||.|||||| |.|||.|. .|||.|..   |.|||. .|
nekvlkdlkithivnvsqekkdafp.ksveYlqvkvedesdeqlssfleraakfladaidsGGrvlvhcvqGksrsssvtvafLikskgwtlkeayeylk

SKRSMVRPNLGFWRQLIAYEQ
 .||.|.|| || .||  .|.
errsivapnrGflkqlakfee
subfamily_MKPLV_pd Subfamily MKPLV 30-150 6.1e-30 97.9 In-house 39-158 (164) alignment 
Range on Protein: 30-150
Range on HMM: 39-158/164.0
SKDEMKKHKITHIINATTEVPNLRSlGDIQRTKLWLEDTPQTYIYPHLELQSDQIQALIADGGKVLVHCVAGVSRSASICLAFLLKYRCRNLREAYHLMK
..  .|. |||||.| ..|  .  .   ..  .. .||.... . ..||  .. .   |  ||.|||||| |.|||.|. .|||.|..   |.|||. .|
nekvlkdlkithivnvsqekkdafp.ksveYlqvkvedesdeqlssfleraakfladaidsGGrvlvhcvqGksrsssvtvafLikskgwtlkeayeylk

SKRSMVRPNLGFWRQLIAYEQ
 .||.|.|| || .||  .|.
errsivapnrGflkqlakfee
subfamily_DSP15_pd Subfamily DSP15 14-153 7.3e-29 94.8 In-house 2-140 (151) alignment 
Range on Protein: 14-153
Range on HMM: 2-140/151.0
MSEIVPGLFICGVSA-LSKDEMKKHKITHIINATTevPNLRSLGDIQRTKLWLEDTPQTYIYPHLELQSDQIQALIADGGKVLVHCVAGVSRSASICLAF
.|...|||.. ..     .. .|...||||..      . . | ||.   . ..|||.. .  ...   . | .    ...|||||.||||||. .. |.
iskvlpglylgnfrdskdeelLkeknithilsvhd..nakkllkdieYkciaasDtpsaklskffkesvefihkcRlkeenvlvhClaGvsRsvtlvvaY

LLKYRCRNLREAYHLMKSKRSMVRPNLGFWRQLIAYEQNVK
|.     | |.| . .| .||.  ||.|| |||  ||..  
lmtvtelnwrdalevikaaRsvanPnfGfkrqlkeyektkl
0048076 (Phosphotyrosine protein) phosphatases II 14-151 8.7e-29 95.4 In-house 4-141 (145) alignment 
Range on Protein: 14-151
Range on HMM: 4-141/145.0
MSEIVPGLFICGV-SALSKDEMKKHKITHIINATTEVPNLRSLgDIQRTKLWLEDTPQTYIYPHLELQSDQIQALIADGGKVLVHCVAGVSRSASICLAF
.|||.|||.. .. .||. ...|...||...| |.| ..|  | .||   | ..| .   .. .|.   ..|......||.||||| |||.|......|.
pseilpglylgslptaldlellkdlgittvlnltselellerl.giqylylpwpDhgvpdllellleflefieealkeggpvlVHCsaGvgRtgtlvaay

LLKYRCRNLREAYHLMKSKRSMVRPNLGFWRQLIAYEQN
|....  .| ||..|..|.|... || |..|.|. .|. 
lmlllgvsleealelvrsqrpgavpnpgqlrflyefele
subfamily_DSP8_pd Subfamily DSP8 14-155 1.5e-28 93.4 In-house 15-157 (159) alignment 
Range on Protein: 14-155
Range on HMM: 15-157/159.0
MSEIVPGLFI-CGVSALSKDEMKKHKITHIINATTEVPNLRSLGDIQRTKLWLEDTPQTYIYPHLELQSDQIQALIADGGKVLVHCVAGVSRSASICLAF
. .|.. |.. . . .||.. ..|  |....|| .. |.|  | . .  .. ..|. .  . | ..   . |.   .  |.||||. || ||||.. .|.
ptrilknlylGsqkdvlseellsklgisyvlnasnscpkleelkeskflrvPvkDkydekllpwfdksvefidkaksengrvlvhvlaGisrsatvaiay

LLKYRCRNLREAYHLMKSKRSMVRPNLGFWRQLIAYEQNVKEN
..|.   .| |||. .|.|| .. ||| |  ||. ||...| .
imktlemsldeayrfvkekrptispnlnflgqLleyekelkll
0048179 (Phosphotyrosine protein) phosphatases II 14-150 7.5e-28 92.4 In-house 4-142 (144) alignment 
Range on Protein: 14-150
Range on HMM: 4-142/144.0
MSEIVPGLFICGVS-ALSKDEMKKHKITHIINATTEVPNLRSLGD-IQRTKLWLEDTPQTYIYPHLELQSDQIQALIADGGKVLVHCVAGVSRSASICLA
.|||.|||.....  ||. ...||..||..|| |.| ..       ||  .| ..| .   .. .|.   . |......||.||||| |||.|......|
pseilpglylgslptaldlellkklgittvinlteeyepefleregiqylhlpwpDhgvpdllellleflefieealeeggpvlVHCsaGvgRtgtlvaa

FLLKYRCRNLREAYHLMKSKRSMVRPNLGFWRQLIAYEQ
.|.|..  .| ||..|..|.|... || |..|.|. ||.
ylmkklglsleealalvrsrrpgavpnpgqlrfLleyek
subfamily_DSP6_pd Subfamily DSP6 13-153 1e-27 90.6 In-house 13-155 (158) alignment 
Range on Protein: 13-153
Range on HMM: 13-155/158.0
AMSEIVPGLFIC-GVSALSKDEMKKHKITHIINATTEVPNL-RSLGDIQRTKLWLEDTPQTYIYPHLELQSDQIQALIADGGKVLVHCVAGVSRSASICL
.  ||.| |..    .|   . .||.|| ...| |...||  .. |... ... .||  .. .  ..    . |.    .  |||||| ||.|||  ..|
fpveilpllylGsakdasnlevlkklkikyvlnvtsnlpnkfeesgelkylqipiedhlsqnlakffPeaiefidearskkskvlvhClaGisrsvtvtl

AFLLKYRCRNLREAYHLMKSKRSMVRPNLGFWRQLIAYEQNVK
|.|.|...  | .||.|.|...| . ||. |  ||. .|....
aylmkklalslndaydlvkkrksnisPnfnfmgqlldferslr
0043147 (Phosphotyrosine protein) phosphatases II 29-152 6.1e-27 89.8 In-house 35-160 (172) alignment 
Range on Protein: 29-152
Range on HMM: 35-160/172.0
LSKDEMKKHKITHIINATTE--VPNLRSLGDIQRTKLWLEDTPQTyIYPHLELQSDQIQA--LIADGGKVLVHCVAGVSRSASICLAFLLKyRCRNLREA
   . .|...||||.|.|..   | | .  .||   |  .| . . .  .|.   ..|.   .. .||.|||||.|||.|.. ...|.|.. .. .| ||
dfwrmlkelgithivnltellydpellerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml.lglsleea

YHLMKSKRSMVRPNLGFWRQLIAYEQNV
..|...||... .| ...|.|  .|. .
valvrekRpgavqnpsqyrflyyfekll
0041856 (Phosphotyrosine protein) phosphatases II 14-151 1.9e-26 88.2 In-house 19-171 (182) alignment 
Range on Protein: 14-151
Range on HMM: 19-171/182.0
MSEIVPGLFICGVS---------------ALSKDEMKKHKITHIINATtEVPNLRSLGDIQRTKLWLEDTPQTYIYPhLELQSDQIQALIADGGKVLVHC
...| ..|....                 |   . .|...||.|.|.| |..   .|   . ....    |   . . |.   | |.. ...||.|||||
ldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt.eelywpellerlgiqylylpwpDhgvpd.ldelldfieevleeggpvlVHC

VAGVSRSASICLAFLLKYRCRNLREAYHLMKSKRS--MVRPNLGFWRQLIAYEQN
 |||.|......|.|.|..  .|.||..|..|.|.   ..|| .|..||...|  
saGvgRtgtlvaaylmkklgvsleeavklvrsrRpgmvitpnqyfflqlallell
subfamily_Slingshot_pd Subfamily Slingshot 27-151 1.9e-26 86.5 In-house 33-156 (169) alignment 
Range on Protein: 27-151
Range on HMM: 33-156/169.0
SALSKDEMKKHKITHIINATTEVPNLRSlGDIQRTKLWLEDTPQTYIYPHLELQSDQIQALIADGGKVLVHCVAGVSRSASICLAFLLKYRCRNLREAYH
 |   .|.|......|.| | |. |  . .... ... . |...| .... .   . |..  ..| ||||||  |||||||. .|. .|    .| ||..
nasnleelkengveyilnvtkeidnffp.ekfeylnirvydeeetdllkywnetykfiekakkkgskvlvhckmGvsrsastviayamkeyglsleeale

LMKSKRSMVRPNLGFWRQLIAYEQN
 .|..||...|| ||..|| .||  
yvkerrsvikPnkgflkqleeyeGi
0045098 (Phosphotyrosine protein) phosphatases II 9-152 5.9e-26 86.9 In-house 17-271 (278) alignment 
Range on Protein: 9-152
Range on HMM: 17-271/278.0
PEYAAMSEIVPGLFICGVS------------------------------------------ALSKDEMKKHKITHIINATTEVPN---------------
.    .||| |.|......                                          |   . .....||.|...|..|..               
lllgipseitpalylgnldknRykdilpydhsrVkdYINAsyidgypkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaqywpeggsl

---------------------------L---------RSLGDIQRTKLWLEDTPQTYIYPHLELQSDQIQALIA--------------DGGKVLVHCVAG
                           |         | .  .. .     ..| . |. ..    ..|.. ..              .||.||||| ||
tygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvlVHCsaG

VSRSASICLAFLLKYR---CRNLREAYHLMKSKRSM-VRPNLGFWRQLIAYEQNV
|.|.. ...|.|....     .| ||.. ..|.| . . .||...|.|. ... .
vgRtGtlvaaylmlelleggvdlleavkelrsqRpglavqnleqyrflyefllel
subfamily_DSP3_pd Subfamily DSP3 11-154 7.4e-26 84.7 In-house 8-159 (162) alignment 
Range on Protein: 11-154
Range on HMM: 8-159/162.0
YAAMSEIVPGLFICGV-SALSKDEMKKHKITHIINATTE----V---PNLRSLGDIQRTKLWLEDTPQTYIYPHLELQSDQIQ-ALIADGGKVLVHCVAG
. .. |. |.|.. .  .|  |...||  |||..||.      |   ..  .  .|. . | ..|.|.. .  . |  .. |. ||  . ||||||||.|
skevdevypklyvgdeavakdkskLkklGithvlnaaegrfskvdtgaefykdleikylGlevdDvpefdlskyFetaakfidealsqkegkvlvhcvvG

VSRSASICLAFLLKYRCRNLREAYHLMKSKRsMVRPNLGFWRQLIAYEQNVKE
||||| . ||.|. .|  .| || . ...|| ...|| || .||.......|.
vsRsatlvlayLmirrkmtlveairtvrkkR.eilPneGFlkqLaeldeelkr
0045450 (Phosphotyrosine protein) phosphatases II 31-150 1e-25 86.6 In-house 118-301 (307) alignment 
Range on Protein: 31-150
Range on HMM: 118-301/307.0
K------DEMKKHKITHIINATTEVPNLR---------------------------SLGDIQRTKLWLEDT-----------------PQTYIYPHLELQ
.        ......|.|.. |..|.. |                            |.......| ..|.                 | . . |..|  
etvedFwrmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfeel

SDQIQALIA------DGGKVLVHCVAGVSRSASICLAFLLKYRC--------RNLREAYHLMKSKRSMVRPNLGFWRQLIAYEQ
 | |... .      .||.||||| |||.|......|.|....          .|.||..|....|. . .|....|.|. ...
ldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeall
0046846 (Phosphotyrosine protein) phosphatases II 8-154 2.2e-25 84.8 In-house 6-174 (176) alignment 
Range on Protein: 8-154
Range on HMM: 6-174/176.0
NPEYAAMSEIVPGLFICGV-----------SALSKDEMKKHKITHIINATTEV-----------PNLRSLGDIQRTKLWLEDTPQTYiyPHLELQSDQIQ
  .   ...|...|....             |   ...|...||...| |.||           | |..||       | . .. ..   .|.   ..|.
lgldldldyinanlilgsrpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgiqylhlpwpDhgvpdl..elllellefir

ALIADGGKVLVHCVAGVSRSASICLAFLLKY-RCRNLREAYHLMKSKRS-MVRPNLGFWRQLIAYEQNVKE
  . .||.|||||.||..|.. ...|.||.. .. .. ||..|....|. .. .. ...|.|  .|. ...
ealkeggpvlVHCsaGigRtgtlvaayllelekglsveealalvreqRplgavqtpeQyrflyefellllk
subfamily_LRR-DSP_pd Subfamily LRR-DSP 15-152 1.3e-24 80.7 In-house 121-258 (263) alignment 
Range on Protein: 15-152
Range on HMM: 121-258/263.0
SEIVPGLFICGV-SALSKDEMKKHKITHIINATTEVPNLrsLGDIQRTKL--WLEDTPQTYIYPHLELQSDQIQALIADGGkVLVHCVAGVSRSASICLA
.||...||. |  ||  |  .|.  .|||. | ...  |    .. .      .||...  |. |.|     |.     || ||||| ||||||... ..
deiidklflGgldsannksilkdlgvthillavadfePl..fPklfkylsiddiedvdeadisqhfeetnafieeGrkkGG.vlvhcraGvsrsstlvis

FLLKYRCRNLREAYHLMKSKRSMVRPNLGFWRQLIAYEQNV
.|.|..  ...||. |...||. ..|| ||  ||  ||...
ylmkkqrlkfkealdlvikkrpriqPnpGfkdqlkkyekkl
0040438 (Phosphotyrosine protein) phosphatases II 34-196 1.4e-24 82.4 In-house 106-315 (317) alignment 
Range on Protein: 34-196
Range on HMM: 106-315/317.0
MKKHKITHIINATTEVPNLR--------------------------SLGDIQRTKLWLEDT----------------PQTYIYPHLELQSDQIQALIAD-
......|.|.. |..... |                           |..|. ..| .||.                |   . |...|  | ..|. .  
vweqgvtvivmLteleelgrekcaqYwplgetltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavreal

---GGKVLVHCVAGVSRSASICLAFLL-----KYRCRNLREAYHLMKSKRSMVRPNLGFWRQLIAYEQNVKenagSVRLVRDEAQPEQLLPDVYLNIAIP
   ||.|||||.|||.|......|.|.     |... .. ||.. ....|... ......|.|. ....        .|.. .|..  |... .|.. ..
edpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleyl....krkltlepaselklkllklliplal

ARPASPEQDPNMIP
 ..  .|.......
ddvklkekelklll
0037934 (Phosphotyrosine protein) phosphatases II 12-150 1.5e-24 82.3 In-house 37-239 (243) alignment 
Range on Protein: 12-150
Range on HMM: 37-239/243.0
AAMSEIVPGLFICGV---------SALSKDEMKKHKITHIINATTEV--------------------------------------------PNLRSLGDI
| .....|.|.....          |   . .....||.|.. |..|                                            ..  .. .|
anliyvtprliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywpgevtygdftvtllseehlddytvrtlllenldlddltrlvi

QRTKLWLED----TPQTYIYPHLELQSDQIQA-----LIADGGKVLVHCVAGVSRSASICLAFLLKYR-CRNLREAYHLMKSKRSM-VRPNLGFWRQLIA
.   |   |    .  . .. .|.   . |..      . .||.|||||.|||.|.. ...|.|.... . .| ||..|....|.. . ......|.|. 
hyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtliaaylmllllgvdleeavkllreqRpgkavqtpsqyrflye

YEQ
...
all
0040439 (Phosphotyrosine protein) phosphatases II 32-150 1.8e-24 82.1 In-house 72-243 (249) alignment 
Range on Protein: 32-150
Range on HMM: 72-243/249.0
DEMKKHKITHIINATTEVPNL------------------------------------------RSLGDIQRTKLWLEDTPQTYIYPHLELQSDQIQALIA
. .....||.|...|..|..                                               ... . ..  | | . . |..|   | |.|.  
rmlwelgitvivmLtslvelgrekcaqywplggsleygdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrk

------DGGKVLVHCVAGVSRSASICLAFLL-----KYRCRNLREAYHLMKSKRSMVRPNLGFWRQLIAYEQ
      .||.||||| |||.|.. ...|.|.     |... .| ||..|..|.|... .|....|.|. ...
aleelpkggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdleeavkllrsqRpgavqnpeqyrflyeall
subfamily_Choan-DSP_MKP-1_pd Subfamily Choan-DSP_MKP-1 15-151 2.2e-24 79.7 In-house 8-146 (148) alignment 
Range on Protein: 15-151
Range on HMM: 8-146/148.0
SEIVPGLFICG--VSALSKDEMKKHKITHIINATTEVPNLRSLGDIQRTKLWLEDTPQTYIYPHLELQSDQIQALIADGGKVLVHCVAGVSRSASICLAF
||| ..    |   ||.. . .|.  .|.|.||| | .|      |.  .. |.| |.  .    |   . ..   ..|..||||.  |||||. . |..
seikdafLFlGskksaadlealkalgvtrivnatkerdnaldqrgieYlhvaldDkpkedlsaiFediiafvrkakdeGrrvLvhlqmGvsrssalallw

LLKYRCRNLREAYHLMKSKRSMVRPNLGFWRQLIAYEQN
|....   |.||. |.|||| .|.||||| .||  .||.
lidfkrvslkealalvkskrryvdpnlgfLkqLaeleqa
0049260 (Phosphotyrosine protein) phosphatases II 31-152 2.4e-24 81.2 In-house 26-149 (152) alignment 
Range on Protein: 31-152
Range on HMM: 26-149/152.0
KDEMKKHKITHIINATTEVPNLR--SLGDIQRTKLWLEDTPQTYIYPHLELQSDQIQA-LIADGGKVLVHCVAGVSRSASICLAFLLKyRCRNLREAYHL
.. .|...||.|.. |..... .      ||   |. .| .   .  .|.   . |.  .. .||.|||||.|||.|.. ...|.|.. .  .| ||. |
wrmlkelgittivmltellelgklkceqyiqylhlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml.lgvsleeaval

MKSKRSMVRPNLGFWRQLIAYEQNV
...||... || |..|.|  .|. .
vrekRpgavpnpgqlrflyefekll
0036282 (Phosphotyrosine protein) phosphatases II 8-151 7.3e-23 76.6 In-house 6-168 (174) alignment 
Range on Protein: 8-151
Range on HMM: 6-168/174.0
NPEYAAMSEIVPGLFICGVSALSKDEMKKHKITHIINATTEVPNL---------------RSLGDIQRTKLWLEDTPQTYIYphLELQSDQIQALIAD--
|  .  .|.| |.|..... .   ...|...||.... ..|...                . ||       |  ... .     |.   ....  ...  
naspldlsyitprliagqgplafwemlkelgittvvmlleekelglykcinywpelredlerlgiqylylpwpDhgvpdlsi..llefvkfveealsedp

GGKVLVHCVAGVSRSASICLAFLLKYRCR-NLREAYHLMKSKR---SMVRPNLGFWRQLIAYEQN
||.||||| |||.|.. ...|.|.... . .|..|..|....|   ... .. ...|.|  .|. 
ggpvlVHCsaGvgRtGtlvaaylmlrglleslvdaldlvrelRlqrpgmvqtpsQyrflyyfekl
PTEN_1 14-154 1.1e-22 75.8 In-house 41-193 (196) alignment 
Range on Protein: 14-154
Range on HMM: 41-193/196.0
MSEIVPGLFICGVSALS--KDEMKKHKITHIINATTEVPN--------LRSLGDIQRTKLWLEDTPQTYIYPHLELQSDQIQALIA--DGGKVLVHCVAG
..|| .||... .. ..  .|..|...||...| . | ..        ..  ....  ..  || .   .  ...   . |..|..  .|..||||| ||
lqeideglyrgslkdvaadldnlkedgitlvvnlseeeelsgrsydleeffksgveylhfpieDhgapslselfdicksfiewllsdpngnvVlVHCkaG

VSRSASICLAFLLKYRCRNLREAYHLMKSKRSMVRPNLGFWRQLIAYEQNVKE
..||. .. |.|....  . .||  |...||. ..|| .....|. |... ..
lgRsGtvvaayLmykgkltadeAlelvrekRppgapnspsqerlleyfaella
0042113 (Phosphotyrosine protein) phosphatases II 14-151 4.9e-22 74.0 In-house 47-241 (245) alignment 
Range on Protein: 14-151
Range on HMM: 47-241/245.0
MSEIVPGLFICGVSALSKDE-----MKKHKITHIINATTEV---------------------------------------------PNLRSLGDIQRTKL
...| |......  . .  |     .....||.|.. |.|.                                             ..  |. .|.   |
gyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywplgesltygdftvtllseehlddytvrtlevtnlgddesrevihyhyl

WLEDTPQTYIYPHLELQSDQIQALIA--DGGKVLVHCVAGVSRSASICLAFLL-----KYRCRNLREAYHLMKSKRSMVRPNLGFWRQLIAYEQN
  .| . . .  .|.   . ..  .|  ..|.||||| |||.|.. ...|.|.     |... .| ||.. ..|.|..........|.|. ....
pwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleqlekelgvsleeavkelrsqRpgavqtpsqyrflyealle
0036941 (Phosphotyrosine protein) phosphatases II 14-152 5.4e-22 73.9 In-house 19-276 (297) alignment 
Range on Protein: 14-152
Range on HMM: 19-276/297.0
MSEIVPGLFICGVSALSKDEMK-----------------------------------------------------------KHKITHIINATTEVPNLRS
..|..| |...  |. .. | .                                                           ....|.|.. |..|.. | 
feellpllllgslsvallpenleknRykdilpydhtRVklddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqnvtvIvmltelvelgre

------------------------------LGDIQRTKLWLED----------------TPQ------TYIYPHLELQSDQIQALIADGGKVLVHCVAGV
                              |.|. ...|...|                 |       .... ..  . .....|. .||.|||||.|||
kcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrkvlkllpsggpvlVHCsaGv

SRSASICLAFLL--------KYRCRNLREAYHLMKSKRSMVRPNLGFWRQLIAYEQNV
.||.....|.|.        |... .. ||.. ....| .. ..|...|.|. .... 
gRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallel
subfamily_STYX_pd Subfamily STYX 12-150 2.4e-21 69.5 In-house 10-155 (166) alignment 
Range on Protein: 12-150
Range on HMM: 10-155/166.0
AAMSEIVPGLFICGVSALSKD---EMKKHKITHIIN------ATTEVPNLRSlgDIQRTKLWLEDTPQTYIYPHLELQSDQIQALIADGGKVLVHCVAGV
  | ||.||||.   ||  |     .||| ||||.       |.   ||..   ...   | . |..   |  .|    . |.  .  |||||||  ||.
remqeilpglflgpysaamksklevlkkhgithivcirqnieanlikpnfpd..rfrylvldvadntveniirylptvkefiddslqkggkvlvhgnagi

SRSASICLAFLLKYRCRNLREAYHLMKSKRSMVRPNLGFWRQLIAYEQ
||||.. .|....    . |||.. .. .|  . || || .||  || 
srsaalviayimetyglkyreafayvqerrfcinpnegfvsqlkeyea
0049772 (Phosphotyrosine protein) phosphatases II 58-150 2.7e-21 72.1 In-house 181-271 (314) alignment 
Range on Protein: 58-150
Range on HMM: 181-271/314.0
IQRTKLWLEDtPQTYIYPHLELQSDQIQALiADGGKVLVHCVAGVSRSAS-ICLAFLLKYRCRNLREAYHLMKSKRSmVRPNLGFWRQLIAYEQ
|.   . ..| ... .  ...   . |...  .||.||||| ||..|... ...|.|.|..  .|.||.. ...||. ..|| ||..||. ||.
ikylripvpD.gsaplledfdeflefieea.dkggpvlvHCkaGkgRtgtfvvaaylmkllgvsleealedvrlkRp.inpnpgfieqleqyef
subfamily_Dicty-DSP19-like_pd Subfamily Dicty-DSP19-like 27-152 3e-21 69.4 In-house 17-152 (154) alignment 
Range on Protein: 27-152
Range on HMM: 17-152/154.0
SALSKDEMKKHKITHIINATTEVPNLRSLG--D------IQRTKLWLEDTPQTYIYPHLELQSDQIQALI--ADGGKVLVHCVAGVSRSASICLAFLLKY
.|| | ......|..|.|  . ..|| .    |      |.  .| | | ..  |  .|..  . |.  |   . .|||||. .||||||.. ...|.. 
aalnkldlqlkniksilnvgiGinnlftdensdindgfiieylnlelfddvnfdiiekldkafefiddaiggvennkvlvhsdkGvsrsaallisylmdk

RCRNLREAYHLMKSKRSMVRPNLGFWRQLIAYEQNV
.  .| .|. |.|. | ...|| || .||  .|.. 
lkislslalellkdsryiikPnqGflkqleifekel
0051082 (Phosphotyrosine protein) phosphatases II 11-149 3.1e-21 71.0 In-house 5-150 (151) alignment 
Range on Protein: 11-149
Range on HMM: 5-150/151.0
YAAMSEIVPGLFICGV-SALSKDEMKKHKITHIINATTEV-----PNLRSLGDIQRTKLWLEDTPQTYIYPHLELQSDQIQALIAD-GGKVLVHCVAGVS
|  .| . .||...|  .|   ...|...|..|.| ..|.     |..    .|. . ....|.| . .  ...   . ...|... .|.||||| ||..
yinfsyvtgglyrsggpladflellkelgiktivnlrseeergycpeylpelgievlhipildwpdpglplsfdavleflellldkkngpvlvHCsaGkg

RSASICLAFLLKyRCRNLREAYHLMKSKRS-MVRPNLGFWRQLIAYE
|.. .....|.. .  .| ||.. ...||  .|.|| .|. ||.|..
RTGtlvalylml.lgvsleealeeyrlkrpgvvqpnqqflfqlfall
0039614 (Phosphotyrosine protein) phosphatases II 33-150 4.3e-21 71.1 In-house 120-286 (297) alignment 
Range on Protein: 33-150
Range on HMM: 120-286/297.0
EMKKHKITHIINATTEVPN------------------------LRSLGDIQRTKLWLEDTPQT-----------------YIYPHLELQSDQIQALIA--
 ......|.|.. |..|..                           |... ...| .... ..                  .  .|    ....  .|  
mvweqgvtvivmLtklvelgrkcaqywpeeggtygdftvtllkvehldgytvrtlevtnngesrtvthfqytgwpdhgvppslellleflelvrealael

-DGGKVLVHCVAGVSRSASICLAFLL-----KYRCRNLREAYHLMKSKRSMVRPNLGFWRQLIAYEQ
 .||.|||||.|||.|......|.|.     |... .. ||.. ....|..........|.|. ...
pkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydall
subfamily_MSG5_pd Subfamily MSG5 42-155 8.1e-18 58.1 In-house 51-163 (165) alignment 
Range on Protein: 42-155
Range on HMM: 51-163/165.0
IINATTEVPNLRSL-GDIQRTKLwlEDTPQTYIYPHLELQSDQIQALIADGGKVLVHCVAGVSRSASICLAFLLKYRCRNLREAYHLMKSKRSMVRPNLG
.|| . |...|. |   ..  ..  | . .. |   |   .  | |  . . |.||||  |.|||||. .|...||    ||.||...||.   . |..|
vinvakeindlellvpavkyyhi..ewehdskivkdlsrltriihaatskrkkilvhcqcglsrsaslivayimkyynlslrdaydklksvaddispsig

FWRQLIAYEQNVKEN
.  ||. .|  ....
lifqlmewevalskk
0043336 (Phosphotyrosine protein) phosphatases II 34-149 1.8e-17 59.2 In-house 108-273 (278) alignment 
Range on Protein: 34-149
Range on HMM: 108-273/278.0
MKKHKITHIINATTEVPNLR-------------------------SLGDIQRTKLWLEDTPQ--------------------TYIYPHLELQSDQIQALI
......|.|.. |..| . |                         .|.|. ...| ....                      . . ..|..  . ..|| 
vwelgvttivmLtelvelgrvkcaqYwpggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldflkavreale

ADGGKVLVHCVAGVSRSASICLAFLL-----KYRCRNLREAYHLMKSKRSMVRPNLGFWRQLIAYE
 ..|.|||||.|||.|.. .....||     |... .| ||.. ....| .  ... ..|.|. ..
dsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyeal
0051429 (Phosphotyrosine protein) phosphatases II 10-158 1.9e-17 59.3 In-house 14-230 (272) alignment 
Range on Protein: 10-158
Range on HMM: 14-230/272.0
EYaaMSEIVPG-LFICGV----SALSKDEMKKHKITHIINATTEV-----PNLRSLGDIQRTKLWLEDTPQTYIYPHL----------------------
 |   ....|| |. .|     .| . . .|...|..|.. ..|.     .  | . .|..  | ..|.  . |  .                       
gy..grvvkpgrlyrsggplpltaadfwrlkelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseellldyilrelllt

--------------------------ELQSDQIQALIAdGGKVLVHCVAGVSRSASICLAFLLKyRCRN--------------LREAYHLMKSKRSMVRP
                          |   . ...| . ||.||||| ||..|.. .....||  .  .              |.||.. ....|  ...
lllsagearevmhlhytdwpdhgvpqeallellellld.ggpvlvHCsaGkdRTGtvvalllll.lgvsletivddYlltnlyleeaveelraqrpgavq

NLGFWRQLIAYEQNVKENAGS
. .....|  ..... ..  |
teeqylflyeallellrslls
0038934 (Phosphotyrosine protein) phosphatases II 14-155 9.7e-17 56.7 In-house 12-179 (194) alignment 
Range on Protein: 14-155
Range on HMM: 12-179/194.0
MSEIVPGLFICGVSALSKD--------------------EMKKHKITHIINATT--EVPNLRSLGD--IQRTKLWLEDT----PQTYIYPHLELQSDQIQ
...|..| ||.  . ||.                     . ...|....|. |    . . . . .  |.  ||  .|     ..  ..  |.|  . ..
vgdiitgrfiafkvPlsgsldkyieelyrfspedlvrylkllnvklglvidltnteryYdpeefekagieylklpfpddgtvPsleillrfldlvdefln

AliADGGKVLVHCVAGVSRSASICLAFLLKYRCRNLREAYHLMKSKRSMVRPNLGFWRQLIAYEQNVKEN
.    ||.|.|||.||..|.. .. |.|..... ...||..|...||  . || .....|  . ......
e..dpggvvaVHCkaGlgRtGtlvaaYLiyrlgmsaeeAialfrekRpgaipnqdyleallkrykelrka
subfamily_STYXL1_pd Subfamily STYXL1 15-154 1.1e-16 54.5 In-house 12-155 (157) alignment 
Range on Protein: 15-154
Range on HMM: 12-155/157.0
SEIVPGLFICGVSA--LSKDEMKKHKITHIINATTEVPNLR-SLGD-IQRTKLWLEDTPQTYIYPHLELQSDQIQALIADGGKVLVHCVAGVSRSASICL
.|..||    |      ..   |  |.   .| ...  .|  .. |  .  .. .||.... . ..|.   . |.    .|  |||    |.||||.. .
vevlPgklylGnykqaqnpaikkdlkvkahvnvsmdadkliagvadvakllhiavedeneadllerlkeavqfiekhkkegevvlvfsnkGisrsaavii

AFLLKYRCRNLREAYHLMKSKRSMVRPNLGFWRQLIAYEQNVKE
|.|. ..  .|..||. .|  .. |.|| .|  ||  .|... .
aylmyskkitlkkaykylkkCkenvkPnrafveqlseWekqllg
subfamily_Sponge-DSP-Subfam1_pd Subfamily Sponge-DSP-Subfam1 70-155 1.6e-16 53.7 In-house 59-144 (145) alignment 
Range on Protein: 70-155
Range on HMM: 59-144/145.0
QTYIYPHLELQSDQIQALIADGGKVLVHCVAGVSRSASICLAFLLKYRCRNLREAYHLMKSKRSMVRPNLGFWRQLIAYEQNVKEN
   .  |..  .| |.    .|  |.|||.|||||| .. .|||.||    | ||   ..|.| .  ||. | ..|.  |...||.
sydlsqhfdevtdfidkgkeegagvfvhcmagvsrsvtvsvaflmkycnmtlseaarqvrsnrllaypnvtflknllnlekqlkee
0047943 (Phosphotyrosine protein) phosphatases II 36-146 9.7e-15 50.2 In-house 99-265 (273) alignment 
Range on Protein: 36-146
Range on HMM: 99-265/273.0
KHKITHIINATTEVPN-----------------------------LRSLGDIQRTKLWLED---------------------TP-QTYIYPHLELQSDQI
......|.  |..| .                               . .|.  ..| |..                     .| .. .  ..  . ...
eqnvrviVmLtelvelgrekcaqYwpleggelsltygkftvtllseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvrka

QALIADGGKVLVHCVAGVSRSASICLAFLL-----KYRCRNLREAYHLMKSKRSMVRPNLGFWRQLI
.. . ..|.|.|||.|||.|........||     |... .. ||..|..|.| .. ... ..|.|.
lealpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrfly
subfamily_PTPMT1_pd Subfamily PTPMT1 36-153 1.5e-13 45.6 In-house 56-169 (171) alignment 
Range on Protein: 36-153
Range on HMM: 56-169/171.0
KHKITHIINATTEVPNLrslgDIQRTKLWLEDTPQTYIYPHLELQSDQIQALIADGGKVLVHCVAGVSRSASICLAFLLKYRCRNLREAYHLMKSKRSMV
 ...... |.| |  .|    ...  .|   |  ..    .||   . |.  . .| .| ||| || .|||..  ..|.| .  .. || . .|.||...
eyelkalansteewkkl....gveqlqlatvDfteapdleklekgvefiekvaskgkrvYvHCkaGrgRsatlvacylmkkeklspeeAlkalkkkRkii

RPNLGFWRQLIAYEQNVK
| .   |..|  ||... 
rlakkqwkalqeyeekll
0051299 (Phosphotyrosine protein) phosphatases II 36-140 1.8e-12 42.8 In-house 114-273 (288) alignment 
Range on Protein: 36-140
Range on HMM: 114-273/288.0
KHKITHIINATTEVPN--------------------------LRSLGDIQRTKLWLEDT------------------------PQTYIYPHLELQSDQIQ
......|.  |..| .                            .|.|.  ..| ....                          ... . |..  . ..
eqnvrvIvmltklvelgrekcaqYwplggsltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdspellldflrlvrk

ALIADGGKVLVHCVAGVSRSASICLAFLL-----KYRCRNLREAYHLMKSKRSMVRPNLG
|| ..|| |.||| |||.|.. .....||     | .. .. ||.. ....| .. ... 
alasgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpe
0050432 (Phosphotyrosine protein) phosphatases II 37-139 5e-11 37.9 In-house 131-285 (308) alignment 
Range on Protein: 37-139
Range on HMM: 131-285/308.0
HKITHIINATTEVPN----------------LRS-------------LGDIQRTKLWLED--TPQT--------------Y----IYPHLELQSDQIQAL
.....|.  |..| |                 .              |.|. ...| |..  ....                   . . |..     . |
qnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseevlddytvrtleltnlgdgesrtvthfhytnWpdhgvPpspeilldflelvrksl

iaDGGKVLVHCVAGVSRSASICLAFLL-----KYRCRNLREAYHLMKSKRSMVRPNL
  .||...||| |||.|.. .... ||     | .. .. ||.. ....| .. ...
..pggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtp
0046845 (Phosphotyrosine protein) phosphatases II 57-138 5.8e-11 37.8 In-house 147-259 (284) alignment 
Range on Protein: 57-138
Range on HMM: 147-259/284.0
DIQRTKLWLED----------------------TP-QTYIYPHLELQSDQIQALIADGGKVLVHCVAGVSRSASICLAFLLKYR--------CRNLREAY
|. ...| |..                      .| .. .  ..  . ....  . .||...||| |||.|.. .... ||...        . .. ||.
dytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrellenlpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleav

HLMKSKRSMVRPN
. ....| .   .
krlreqRpgmvqt
subfamily_Laforin_pd Subfamily Laforin 84-135 3.4e-07 23.3 In-house 103-154 (183) alignment 
Range on Protein: 84-135
Range on HMM: 103-154/183.0
IQALIADGGKVLVHCVAGVSRSASICLAFLLKYRCRNLREAYHLMKSKRSMV
..||. .| .| ||| ||| ||..|   ||      .|.   . . .|| .|
lhallekghivyvhcnagvgrstaivcgflqyvlgwslakvqyfllakrpvv
PTPc_DSPc_SM00012 85-120 2e-06 23.3 In-house 38-68 (105) alignment 
Range on Protein: 85-120
Range on HMM: 38-68/105.0
QaliadGGKVLVHCVAGVSRSASICLAFLLKYRCRN
.     .. |.||| |||.|.. .... .|  ....
s.....skpvvVhCsaGvgRtgtfvaldillqqlek
0048567 (Phosphotyrosine protein) phosphatases II 90-142 2.4e-06 22.0 In-house 73-124 (157) alignment 
Range on Protein: 90-142
Range on HMM: 73-124/157.0
DGGKVLVHCVAGV---SRSASICLAFLLKYRCRNLREAYHLMkskrSMVRPNLGFW
 |... ||| ||    .|.| .. ..|...   . .||....    ..|||..  .
agkaiavhckaglkkrgrtatLigcYlilhlgftpeeaiapl....rivrpgsvpf