Synonym: CELE_F38H4.4, F38H4.4
Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
| Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
|---|---|---|---|---|---|---|---|---|---|
| subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 179-481 | 1.8e-204 | 671.9 | In-house | 1-303 (303) | alignment | ||
Range on Protein: 179-481
Range on HMM: 1-303/303.0
NTEEKKQKWLGLAKRFVDEDANIAANDFEQVVSYIPPSVTKHQFVKNMHKNRFADVICLDHSKVHLSDSSYIHASYLELDTQKRAILTQLPLPHTSADFW
..|||||||..||||..|||||||.|.||.||||.||||.|.||||||.||||.||||||||||.|||||||||||||||..|.||||||||.||.||||
iseekkqkwkllakrtldedaniavnefekvvsylppsvsknqfvknmdknrfvdvicldhskvklsdssyihasyleldsskkailtqlplshtaadfw
QMIIEQRVKCVLLLLTDSEYDSLGGDFVFPRNQDFLNFEERSIRVGEFKRVEIMDGWVLKVVSVSNGDYKSFLHIHHYNAWPHNNIPGNGSPKFVKQIWQ
||||||.||||||||||||||.||||.|||||||||.|||||||||||||||..|||||||.||||||||||||.|||.|||||.||..|||||||||||
qmiieqkvkcvlllltdseydklggdsvfprnqdflkfeersirvgefkrvelgdgwvlkvlsvsngdyksflhvhhykawphnsipsdgspkfvkqiwq
LQSVLRKYSPSTPTVYMSLSGCGRAGTFALFETAHLSLHSEQATLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAEHILDNGFCKLAIPKKPNDEKDKE
|||||||||.|||||||||||||||||||||||||||||||||.||||||||.|||||.||.|||.|||.||||||||.||||.||||||||||||||||
lqsvlrkysdstptvymslsgcgragtfalfetahlslhseqasldlvkclenvrngrlhavqnlsqfsvvytllaehvldngicklaipkkpndekdke
KDK
|||
kdk
|
|||||||||
| 0040438 | (Phosphotyrosine protein) phosphatases II | 187-480 | 2.8e-58 | 193.0 | In-house | 5-299 (317) | alignment | ||
Range on Protein: 187-480
Range on HMM: 5-299/317.0
WLGLAKRFVDEDANIAANDFEQVVSYIPPSVTKHQFVKNMHKNRFADVICLDHSKVHLSD------SSYIHASYLELDT-QKRAILTQLPLPHTSADFWQ
.| . .... |... . ||.. |..... . ....|..|||. |....|||.|.||. |.||.||| . ... |.|| |||.| .|||.
lllalldllksdftalleefedllslkldtysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPlpntvedFwr
MIIEQRVKCVLLLLTDSEYDSLGGDFVFPRnQDFLNFEERSIRVGEFKRveiMDGWVLKVVSVS--NGDYKSFLHIHHYNAWPHNNIP--GNGSPKFVKQ
|. ||.|.... | . |.. . .| ...|.... .... ... ..|..| .. |. ..... .....|| .||. ..| . .|...
mvweqgvtvivmLteleelgrekcaqYwpl.getltygdftvtllseee...lagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldflea
IWQLQSvlrkySPSTPTVYMSLSGCGRAGTFALFETAHLSLHSEQaTLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAEHILDNGFCKLAIPKKPNDEK
... .. .|..|.. .. |.||.|||.. .... |. |. ..|. ......|. | .|.|.. |. |.|..|.|... .. .. | ..| |
vreale.....dpggpvlVHCsaGvgRtGtfiaaylmleqlekeg.gvdveeavkelreqRpgavqtpeqyrflydalleylkrkltlepaselklkllk
DKEKD
....
llipl
|
|||||||||
| 0036941 | (Phosphotyrosine protein) phosphatases II | 213-467 | 2.3e-55 | 183.4 | In-house | 27-287 (297) | alignment | ||
Range on Protein: 213-467
Range on HMM: 27-287/297.0
IPPSVTKHQFVKNMHKNRFADVICLDHSKVHLSDSS--YIHASYLELDT-QKRAILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDSEYDSLGGDFVFPR
...| . ....|..|||. |....||. |.|.|.. ||.|||... ... |.|| |||.| .|||.|. ||.|.... | .. |.. . .|
llgslsvallpenleknRykdilpydhtRVklddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqnvtvIvmltelvelgrekcaqywpl
N-QDFLNFEERSIRVGEFKRVeIMDGWVLKVVSVSN--GDYKSFLHIHHYNAWPHNNIPGnGSPKFVKQIWQLQSVLRKYSPSTPTVYMSLSGCGRAGTF
. ...|.... .... ... | . |...| .. |.. .... .....|| ||....| ... |.....||... ...|.. .. |.||.|||
eegesltygdftvtllsvevv.llddytlrtlevtdtgngesrtvthfhytgwpdhgvpe.spaslldfielvrkvlkllpsggpvlVHCsaGvgRsgtf
ALFETAHLSLHS--EQATLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAEHILDNGFCKLAI
.. .... |.. .. ..|..... ..|. | .|.|.| |. |.| .|.|... . .. ..
iaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallellkkkltkepll
|
|||||||||
| 0039614 | (Phosphotyrosine protein) phosphatases II | 200-458 | 7.8e-53 | 175.2 | In-house | 32-290 (297) | alignment | ||
Range on Protein: 200-458
Range on HMM: 32-290/297.0
NIAANDFEQVVSYIPPsVTKHQFVKNMHKNRFADVICLDHSKVHL-------SDSSYIHASYLELDT--QKRAILTQLPLPHTSADFWQMIIEQRVKCVL
.. ..||...|..|. . ....|..|||. |....||| |.| ||.||.|||.. ... |.|| |||.| .|||.|. ||.|....
tllllefeellslkpd.ysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIatqgPlpetvedFwrmvweqgvtviv
LLLTDSEYDSlGGDFVFPRNQDflNFEERSIRVGEFKRveiMDGWVLKVVSVSNGDYKSFLHIHHYNAWPHNNIP--GNGSPKFVKQIWQLQSVLrkySP
| . |.. . .| ... .... .... ... ||... . .|.|... ... ..| ||....| . .|...... .. | ..
mLtklvelgr.kcaqywpeegg..tygdftvtllkveh...ldgytvrtlevtnngesrtvthfqytgwpdhgvppslellleflelvrealael...pk
STPTVYMSLSGCGRAGTFALFETAHLSLHSEqATLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAEHIL
..|.. .. |.||.|||.. ... |..| ..|. ......|. | .|.|.. |. |.| .|.|...
ggpvlVHCsaGvgRtGtfiaaylmleqleke.ggvdvleavkelreqRpgavqtpsqyrflydallellk
|
|||||||||
| 0051299 | (Phosphotyrosine protein) phosphatases II | 178-457 | 1.2e-52 | 174.5 | In-house | 1-286 (288) | alignment | ||
Range on Protein: 178-457
Range on HMM: 1-286/288.0
GNTEEKKQKWLGLAKRFVDEDANIAANDFEQVVSYI-PPSVTKHQFVKNMHKNRFADVICLDHSKVHLS------DSSYIHASYLEL-DTQKRAILTQLP
|.|| . ...| | .... . .. .. ||...|.. ..... .....|..|||. |....|||.|.|| .|.||.|||... ..... |.|| |
gdteisveellklvlkllangltglleefeellsllpdltlsaallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyidgynlkrkfIatqgP
LPHTSADFWQMIIEQRVKCVLLLLTDSEYDSLGGDFVFPRnQDFLNFEERSIRVGEFKRveiMDGWVLKVVSVS------NGDYKSFLHIHHYNAWPHNN
||.| .|||.|. ||.|... | . |.. . .| ...|.... ... . . .|.... .. |. .... . ...|| .||...
lpntvedFWrmvweqnvrvIvmltklvelgrekcaqYwpl.ggsltygditvtllseev...lddytvrtlevtnldlldgdgesrtvthfhytnwpdhg
IP--GNGSPKFVKQIWQLQSvlrkySPSTPTVYMSLSGCGRAGTFALFETAHLSLHSEqATLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAEHI
.| . .|...... .. |.. |.| .. |.||.|||.. .... |. | ..|. . ....|. | ...|.. |. ||| .|.|..
vpdspellldflrlvrkala.....sgggpvvVHCsaGvgRtgtfialdllleqleke.ggvdvleavkrlreqRpgmvqtpeqyrfvyealleyl
|
|||||||||
| DSPc_SM00195 | 212-456 | 1.4e-52 | 174.0 | In-house | 13-261 (263) | alignment | |||
Range on Protein: 212-456
Range on HMM: 13-261/263.0
YIPPSVTKHQFVKNMHKNRFADVICLDHSKVHLSD------SSYIHASYLELD-TQKRAILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDSEYDSLGGD
. | ..|. .. ||..|||. .... ||..|.|.. |.||.|.|.... .|. |.|| |||.| .|||.|..|..||... | ..| .. |
tspketteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengkekcd
FVFPRN-QDFLNFEERSIRVGEFKRVEimDGWVLKVVSVSNGD--YKSFLHIHHYNAWPHNNIP--GNGSPKFVKQIWQLQSVLrkyspSTPTVYMSLSG
.|.. .. .|.. |. . | . .. | ..|....... . . ... ..|..||....| . ...... . .| |.|.| .. |
rywpeesggketfgkisvklvevekkk..deiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkksksts.....sgpivVhCsaG
CGRAGTFALFETAHLSLHSEQAtLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAEH
.||.|||.. ... .|..|. .|. ......|. |....|.|.|..|.|. ..|
vgRtgtfvtidiilskleeekk.vdifeivkelRkqRpgmvqtleqYlfiyeailey
|
|||||||||
| PTPc_SM00194 | 212-456 | 1.4e-52 | 174.0 | In-house | 13-261 (263) | alignment | |||
Range on Protein: 212-456
Range on HMM: 13-261/263.0
YIPPSVTKHQFVKNMHKNRFADVICLDHSKVHLSD------SSYIHASYLELD-TQKRAILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDSEYDSLGGD
. | ..|. .. ||..|||. .... ||..|.|.. |.||.|.|.... .|. |.|| |||.| .|||.|..|..||... | ..| .. |
tspketteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengkekcd
FVFPRN-QDFLNFEERSIRVGEFKRVEimDGWVLKVVSVSNGD--YKSFLHIHHYNAWPHNNIP--GNGSPKFVKQIWQLQSVLrkyspSTPTVYMSLSG
.|.. .. .|.. |. . | . .. | ..|....... . . ... ..|..||....| . ...... . .| |.|.| .. |
rywpeesggketfgkisvklvevekkk..deiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkksksts.....sgpivVhCsaG
CGRAGTFALFETAHLSLHSEQAtLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAEH
.||.|||.. ... .|..|. .|. ......|. |....|.|.|..|.|. ..|
vgRtgtfvtidiilskleeekk.vdifeivkelRkqRpgmvqtleqYlfiyeailey
|
|||||||||
| 0046845 | (Phosphotyrosine protein) phosphatases II | 205-459 | 2.1e-52 | 173.6 | In-house | 5-276 (284) | alignment | ||
Range on Protein: 205-459
Range on HMM: 5-276/284.0
DFEQVVSYIPP---SVTKHQFVKNMHKNRFADVICLDHSKVHL-------SDSSYIHASYLEL------DTQKRAILTQLPLPHTSADFWQMIIEQRVKC
.||...|. .. |.. ....|..|||. |....|||.|.| .||.||.|||.. ...|. |.|| |||.| .|||.|. ||.|..
efeellsltvklllslsvallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqnvrv
VLLLLTDSEYDSLGGDFVFPRNQDFLNFEERSIRVGEFKRveiMDGWVLKVVSVSN---GDYKSFLHIHHYNAWPHNNIPGNgSPKFVKQIWQLQSVLRK
. | . |.. .. .| ....|.... .... . . .|.... .....| ... .....|| .||....| . . ... .......|..
IVmltelvengrekcaqYwplegevltygdftvtllseev...kddytvrtleltnlgytgesrtvthfhytswpdhgvpps.pedlleflrlvrellen
YSPSTPTVYMSLSGCGRAGTFALFETAHLSLHSEQA--TLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAEHILD
.... |.| .. |.||.|||.. .... |. |. ..|. ... ..|. | .. |.| |. ||| .|.|...
lpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleylkl
|
|||||||||
| 0045450 | (Phosphotyrosine protein) phosphatases II | 207-459 | 2.9e-52 | 173.7 | In-house | 37-306 (307) | alignment | ||
Range on Protein: 207-459
Range on HMM: 37-306/307.0
EQVVSYIPPSVTKHQFVKNMHKNRFADVICLDHSKVHL-------SDSSYIHASYLELD---------TQKRAILTQLPLPHTSADFWQMIIEQRVKCVL
.| ... . . ....|..|||. |....||. |.| .||.||.||| .. ... |.|| |||.| .|||.|. ||.|....
lsvtvfllgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydlkrkfIatqgPlpetvedFwrmlweqgvtviv
LLLTDSEYDSLGGDFVFPRNQDFLNFEERSIRVGEFKRveiMDGWVLKVVSVS---NGDYKSFLHIHHYNAWPHNNIPG--NGSPKFVKQIWQlqsVLRK
| .. |... . .| ....|.... ... ... .||... .. |. .. .....|| .||. ..| . .|...... .|..
mltelvelgrekcaqywPdegeeltygnftvtllseeh...ldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfeelldfieevrk...alee
YSPSTPTVYMSLSGCGRAGTFALFETAHLSLHSEQAT--LDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAEHILD
.....|.. .. |.||.|||.. .. |..|. . .|| ......|. | .|.||. |. |.| .|.|..|.
lpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeallelllk
|
|||||||||
| Y_phosphatase | Protein-tyrosine phosphatase | 225-455 | 8e-52 | 171.4 | Pfam-A | 1-235 (235) | alignment | ||
Range on Protein: 225-455
Range on HMM: 1-235/235.0
NMHKNRFADVICLDHSKVHL----SDSSYIHASYLE-LDTQKRAILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDSEYDSLGGDFVFP-RNQDFLNFEE
|..|||. |... |...|.| ..| ||.|.|.. ...|. |.|| ||..| .|||.|.....||.. .| .. | .. . .| .....|....
nkkknRykdilpydktrvklkgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesltygd
RSIRVGeFKRVEIMDGWVLKVVSVSNGDYKS---FLHIHHYNAWPHNNIPGNgspkfVKQIWQLQSVLRKYS--PSTPTVYMSLSGCGRAGTFALFETAH
.... | |......|....... . .| .. .||..||....| . .|....| ..|.. |.|.| .. |.||.|||.. ...
ikvelk.ekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpes.....pkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldill
LSLHSEQAtLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAE
.|..|. .|........|. |....|.|.|. |.| ...|
eqleaeee.vdvlqivkelRkqRpgmvqsleqYiflykaile
|
|||||||||
| Y_phosphatase | Protein-tyrosine phosphatase | 225-455 | 8e-52 | 171.4 | In-house | 1-235 (235) | alignment | ||
Range on Protein: 225-455
Range on HMM: 1-235/235.0
NMHKNRFADVICLDHSKVHL----SDSSYIHASYLE-LDTQKRAILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDSEYDSLGGDFVFP-RNQDFLNFEE
|..|||. |... |...|.| ..| ||.|.|.. ...|. |.|| ||..| .|||.|.....||.. .| .. | .. . .| .....|....
nkkknRykdilpydktrvklkgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesltygd
RSIRVGeFKRVEIMDGWVLKVVSVSNGDYKS---FLHIHHYNAWPHNNIPGNgspkfVKQIWQLQSVLRKYS--PSTPTVYMSLSGCGRAGTFALFETAH
.... | |......|....... . .| .. .||..||....| . .|....| ..|.. |.|.| .. |.||.|||.. ...
ikvelk.ekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpes.....pkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldill
LSLHSEQAtLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAE
.|..|. .|........|. |....|.|.|. |.| ...|
eqleaeee.vdvlqivkelRkqRpgmvqsleqYiflykaile
|
|||||||||
| 0050432 | (Phosphotyrosine protein) phosphatases II | 209-458 | 1.2e-51 | 171.3 | In-house | 51-300 (308) | alignment | ||
Range on Protein: 209-458
Range on HMM: 51-300/308.0
VVSYI-PPSVTKHQFVKNMHKNRFADVICLDHSKVHLS-DSSYIHASYLEL---DTQKRAILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDSEYDSLGG
. |. ... . ....|..|||. |....||| |.|. .|.||.||| . . ... |.|| |||.| .|||.|. ||.|... | . |..
llsvkplleysvallpenkdkNrykdilpydhsRVkldegsdYInAsyvdgyssklprkfIatqgPlpntvedFwrmvweqnvrvIvmLtklvengrekc
DFVFPRN--QDFLNFEERSIRVGEFKRveiMDGWVLKVVSVSN--GDYKSFLHIHHYNAWPHNNIPGNgspkfVKQIWQLQSVLRKYSPSTPTVYMSLSG
. .| . ...|... .... . . .|.... .. ..| ... .... || .||. ..| . ....... .||. |. |.| .. |
aqYwplelgggsleygkftvtllseev...lddytvrtleltnlgdgesrtvthfhytnWpdhgvPps.....peilldflelvrkslpggpivVHCsaG
CGRAGTFALFETAHLSLHSEqATLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAEHIL
.||.|||.. .... |. | ..|. ... ..| | .. |.. |. |.| .|.|...
vGRtGtfialdllleqleke.ggvdvfeavkklReqRpgmvqtpeqylflyralleylk
|
|||||||||
| 0043336 | (Phosphotyrosine protein) phosphatases II | 201-457 | 4.4e-51 | 169.4 | In-house | 21-277 (278) | alignment | ||
Range on Protein: 201-457
Range on HMM: 21-277/278.0
IAANDFEQVVSYIPPSVTKHQFVKNMHKNRFADVICLDHSKVHLSD------SSYIHASYLELDT-QKRAILTQLPLPHTSADFWQMIIEQRVKCVLLLL
. ..||.. |. ... . ....|..|||. |....||| |.||. |.||.|||... ... |.|| |||.| .|||.|. |..|.... |
llllefeellsfkldtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpetvedFwrmvwelgvttivmLt
TDSEYDSLGGDFVFPrnQDFLNFEERSIRVGEFKRveiMDGWVLKVVSVS--NGDYKSFLHIHHYNAWPHNNIPGnGSP---KFVKQIWQLQSvlrkySP
.. |... . . .| ...|.... .... ... .|.... . |. ... . ...|| .||....| .|.|.... .. ..
elvelgrvkcaqYwp..ggsltygdftvtllkeeh...lddytvrtlevtnlgdgesrtvthyhylgwpdhgvpe.slsllldflkavreale.....ds
STPTVYMSLSGCGRAGTFALFETAHLSLHSEQaTLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAEHI
..|.. .. |.||.|||.. .... |..|. ..|| ......|. | .|.|.. |. |.| .|.|..
ngpvlVHCsaGvgRTGtfialyllleqlekeg.gvdleeavkelreqRpgavqtpsqyrflyealleyl
|
|||||||||
| 0045098 | (Phosphotyrosine protein) phosphatases II | 204-458 | 5.4e-50 | 165.7 | In-house | 12-273 (278) | alignment | ||
Range on Protein: 204-458
Range on HMM: 12-273/278.0
NDFEQVVSYIPPSVTKHQFVKNMHKNRFADVICLDHSKVHlsdsSYIHASYLELDtQKRAILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDSEYDSLGG
..... .|| ..| .....|..|||. |....||| |. ||.|||.. .|. |.|| |||.| ||||.|. |....... | . |..
efefllllgipseitpalylgnldknRykdilpydhsrVk....dYINAsyidgy.pkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekc
DFVFPRnQDFLNFEERSIRVGEFKRVEIMDGWVLKVVSV---SNGDYKSFLHIHHYNAWPHNNIPGNG----SPKFVKQIWQLQSVLRKY--------SP
. .| ...|.... .... ...... . ..|.|. . ..... .....|| || ...| . .....| . ...| .. ..
aqywpe.ggsltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllssllllds
STPTVYMSLSGCGRAGTFALFETAHLSLhseQATLDLVKCLEMVRNGRIH-ACQNLTQFSFVYTLLAEHIL
..|.. |.||.||... . | . ..|| ......|. | . |.||| |. |.| .|.|..|
ggpvlVHCsaGvgRtGtlvaaylmlell...eggvdlleavkelrsqRpglavqnleqyrflyefllelll
|
|||||||||
| 0047943 | (Phosphotyrosine protein) phosphatases II | 212-457 | 2.4e-49 | 163.6 | In-house | 24-272 (273) | alignment | ||
Range on Protein: 212-457
Range on HMM: 24-272/273.0
YI-PPSVTKHQFVKNMHKNRFADVICLDHSKVHL--SDSSYIHASYLEL-DTQKRAILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDSEYDSLGGDFVF
.. . . . ....|..|||. |....||| |.| ..|.||.|||... ..... |.|| |||.| .|||.|. ||.|... | .. | . . .
lkplltysvallpenkdknrykdilpydhsrvklgdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvweqnvrviVmLtelvelgrekcaqYw
PRNQD--FLNFEERSIRVGEFKRveiMDGWVLKVVSVSN--GDYKSFLHIHHYNAWPHNNIPGnGSPKFVKQIWQLQSVLRKYSPSTPTVYMSLSGCGRA
| ... .|.... .... . . |.... .. ..| ... . ...|| || ...| ... |......|... ..|.| .. |.||.
pleggelsltygkftvtllseet...kddytvrtleltnlgtgesrtvthfhytgwpdhgvpp.slesllefielvrkalealpsngpvvVHCsaGvgRt
GTFALFETAHLSLHSEqATLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAEHI
|||.. .... |. | ..|. ... ..|. | .. |.. |. |.| .|.|..
gtfialdllldqleke.ggvdvleavkllrsqRpgmvqtpeqyrflyealleyl
|
|||||||||
| 0040439 | (Phosphotyrosine protein) phosphatases II | 218-458 | 2.1e-46 | 154.0 | In-house | 4-247 (249) | alignment | ||
Range on Protein: 218-458
Range on HMM: 4-247/249.0
TKHQFVKNMHKNRFADVICLDHSKVHLSD------SSYIHASYLELDT-QKRAILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDSEYDSLGGDFVFPRn
. ....|..|||. |....||| |.||. |.||.|||... ..| |.|| |||.| .|||.|. |....... | .. |.. . . .|
svallpenkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywpl.
QDFLNFEERSIRVGEFKRveiMDGWVLKVVSVSNGDYKSFLHIHHYN--AWPHNNIP--GNGSPKFVKQIWQLQSVLrkySPSTPTVYMSLSGCGRAGTF
...|.... .... ... .|.... .. ..| ... ....|.. ||. ..| . .|...... .. | ....|.. .. |.||.|||
ggsleygdftvtllsvev...kddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleel...pkggpvlVHCsaGvgRtGtf
ALFETAHLSLHSEQAtLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAEHIL
.. ... |. |. .|| .....|. | .|.||. |. |.| .|.|..|
iaaylmleqlekelg.vdleeavkllrsqRpgavqnpeqyrflyeallelll
|
|||||||||
| 0037934 | (Phosphotyrosine protein) phosphatases II | 220-456 | 1.1e-45 | 151.5 | In-house | 5-241 (243) | alignment | ||
Range on Protein: 220-456
Range on HMM: 5-241/243.0
HQFVKNMHKNRFADVICLDHSKVHLSDSSYIHASYLELDtqKRAILTQLPLPHTSAD----FWQMIIEQRVKCVLLLLTDSEYDSLGGDFVFPrnQDFlN
.... |..|||. |....||| |.|..|.||.|.. . .| |.||.|||.| .| ||.|. |....... | .. |.. .. . .| ... .
allpenlsknrysdilpydhsrvklegsdyinanliyvt..prliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywp..gev.t
FEERSIRvgeFKRVEIMDGWVLKVVSVSN---GDYKSFLHIHHYNAWPHNNIPG--NGSPKFVKQIWQLQSV---LRKYSPSTPTVYMSLSGCGRAGTFA
... ... .. .| .|.... .....| .|.. . . .|| .||....| . .|...... .. |...... |.. . |.||.||..
ygdftvt...llseehlddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtli
LFETAHLSLhseqaTLDLVKCLEMVRNGRIH-ACQNLTQFSFVYTLLAEH
. . .| | ..|| ......|. | . |.|.. |. |.| .|.|.
aaylmllll.....gvdleeavkllreqRpgkavqtpsqyrflyeallel
|
|||||||||
| 0042113 | (Phosphotyrosine protein) phosphatases II | 220-455 | 1.2e-44 | 147.9 | In-house | 4-241 (245) | alignment | ||
Range on Protein: 220-455
Range on HMM: 4-241/245.0
HQFVKNMHKNRFADVICLDHSKVHLS------DSSYIHASYLELDT-QKRAILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDSEYDSLGGDFVFPRnQD
....|..|||. |....||. |.|| ||.||.||| .. .. |.|| |||.| .|||.|. |....... | .. |.. . . .| ..
allpenkdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywpl.ge
FLNFEERSIRVGEFKRveiMDGWVLKVVSVS--NGDYKSFLHIHHYNAWPHNNIP--GNGSPKFVKQIWQLQSVlrkySPSTPTVYMSLSGCGRAGTFAL
.|.... .... ... .|.... ...|. |.. . . .|| ||....| . .|.. ... .. ....|.. .. |.||.|||..
sltygdftvtllseeh...lddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldflefvrkalae....dsngpvlVHCsaGvgRtGtfia
FETAHLSLHSEQaTLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAE
... |..|. ...| ......|. | .|.|.. |. |.| .|.|
aylmleqlekel.gvsleeavkelrsqRpgavqtpsqyrflyealle
|
|||||||||
| subfamily_PTPRD_pd | Subfamily PTPRD | 206-457 | 6.6e-33 | 109.2 | In-house | 29-281 (564) | alignment | ||
Range on Protein: 206-457
Range on HMM: 29-281/564.0
FEQVVSYIPPSVTKHQFVKNMHKNRFADVICLDHSKVHL------SDSSYIHASYLEL-DTQKRAILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDSEY
.... . .... . | .|||.|... ||| | | ..| || ||... ...| | || ||..| .|||.|. ||..... .| .|
ykkieegqqftweaankpaNkaKNRyanivaYdhsRVvLskvegdegsDYINAsfidgyrkrkayIAtqgPlaetiedFWRmvweqnsstiVmltkleEk
DSLGGDFVFPRNQdFLNFEERSIRVGEFKRVEIMDGWVLKVvSVSNGDYKSFLHIHHYNAWPHNNIPGNGSP--KFVKQIWQLQSvlrkySPSTPTVYMS
. . .| .. ...| . . | .... . .|. . .. . . . |. .||....| .. . ...... .|.. . . |.|
gkvkchkYWPekg.tetygeltVtleeeeeladyeirtfkl.kkkkssesreVrqFhFtsWPdhgvpesatslLdlirkvralne.....pdagPivVhC
LSGCGRAGTFALFETAhLSLHSEQATLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAEHI
.| || ||| . | |..|.|. ......|. | . |. .|..|... ..| .
SaGVGRTGtfividam.lerikeektvDiyqyvkalrkqRnamVqteeQYiFiheaileal
|
|||||||||
| subfamily_PTPN12_pd | Subfamily PTPN12 | 222-456 | 1.7e-32 | 107.4 | In-house | 37-276 (290) | alignment | ||
Range on Protein: 222-456
Range on HMM: 37-276/290.0
FVKNMHKNRFADVICLDHSKVHLS------DSSYIHASYLELDT-QKRAILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDSEYDSLGGDFVFPRNQDF-
.|..|||. |.. |.|.|.|| .|.|| |.... . ... | .| |||.| |||.||.|..|. |... | . . .| ...
keenvkknrykDilPydksrvelskieeeegsdYinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCerYWpeegeee
LNFEERSIRVGEFKRveIMDGWVLKVVSVSNGDYKSFLHIHHYNAWPHNNIPGNgSPKFVKQIWQLQSVLRkySPSTPTVYMSLSGCGRAGTFALFETAH
|.|.| .. . | |. . |..... . | . . . .. ||.||| ..| . . .. |...... . | ..| | .|.||.|| . ..
lefgefevtleeeka..vdddflirtLkveaqkesrkvyqfhYtaWPDhgvPss.aksllelielvrelqe..sedaPlvvhCsaGvGrtGtiiaidyvr
LSLHSEQA--TLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAEH
|..|. .||. . . .|. | . | |...|| .||
ellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavael
|
|||||||||
| subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 223-456 | 3e-32 | 107.0 | In-house | 54-289 (298) | alignment | ||
Range on Protein: 223-456
Range on HMM: 54-289/298.0
VKNMHKNRFADVICLDHSKVHLSD------SSYIHASYLELDTQK-RAILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDSEYDSLGGDFVFPRNQDfLN
.| .|||.||.| ||.|.| |.. | || ||.|. ... |.|| ||..| .|||.|..|. .... .| . | | . .| .. .
penkkkNRyadiialdssRvvLekedadeesdYiNAsflhaykgrnafiatqaPltetvedFWrmvteedigtiVmltnleeldktkyhkywPdegk.et
FEERSIRVGEFKRVEIMDGWVLKVVSVSNGDYKSFLHIHHyNAWPHNNIPGNGSPkFVKQIWQLQSvLRKYSPSTPTVYMSLSGCGRAGTFALFETAHLS
..| .... . .. . ||| . .. . .. ..|. || . .| | . .. . . . .. . .| . .| ||.||| ..
ygeitvsllskeefadlivrklkvskkkeekerevrqlhf.tsWpdkgvpenats.vldllrkvra.sqqqagnkpvivqCsaGvgRsGtfiaidsvler
LHSEQaTLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAEH
.. || ..|. . ....|. |..| | .|..|.|.. |
vkkeq.vvDvfqvvkvlRkkrpgavqteeqYvfiyeavlea
|
|||||||||
| subfamily_PTPN1_pd | Subfamily PTPN1 | 217-455 | 3.8e-32 | 106.2 | In-house | 24-269 (290) | alignment | ||
Range on Protein: 217-455
Range on HMM: 24-269/290.0
VTKHQFVKNMHKNRFADVICLDHSKVHLS--DSSYIHASYLELDT-QKRAILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDSEYDSLGGDFVFPRNQD-
... .. .| .||. || |||...| | || || .||. ... |||| |||.| . ||||. ||. |.|..| | ... .|....
treaklpenrnlnryrdvspydhsrikleradndyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvvekeqikcaqywPqgeee
-FLNFEERSIRVgEFKRVEIMDGWVLKVVSVSN---GDYKSFLHiHHYNAWPHNNIPGNgSPKFVKQIWQLQSVLRKYSPSTPTVYMSLSGCGRAGTFAL
| .|. ...| .. . |. . ...... . | . .. || .|| .|| .| .|.| ...... | |.| .| ||.|||.|
kellledtklkv.kliseerksyytvrllelenlktqetreilh.fhyttwpdfgvpes.paaflkflfkvresGslssdvGpavihcsaGiGrsGtfcl
FETAHLSLHSEQA--TLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAE
.| . .. .. ..|. | | .|. |. | |. | |. . |
vdtclvliekkddlssvdikkvllelrkyrlGliqtadqlrfsylaile
|
|||||||||
| subfamily_PTPRB_pd | Subfamily PTPRB | 216-455 | 1e-31 | 105.1 | In-house | 42-283 (293) | alignment | ||
Range on Protein: 216-455
Range on HMM: 42-283/293.0
SVTKHQFVKNMHKNRFADVICLDHSKVHL------SDSSYIHASYLELDT-QKRAILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDSEYDSLGGDFVFP
.|.. . .| |||. ... |||.|.| |.| || |.|.. . .. | || |||.| |||.|. |.... ...| | . .|
avkaaelavnraknrytnilpydhsrvkLaalkdesgsDYinanyipgynsprefiatqGPlpetvddfWrmvwekkssiivmltqlvekgkvkCeeYWP
RNQDFLNFEErsIRVgEFKRVEIMDGWVLKVVSVSNGDYKSFLHIHHYNAWPHNNIPGNGSpKFVKQIWQLQSVLRKYSPSTPTVYMSLSGCGRAGTFAL
.... .. . |.| ... | .. ||.. ....... . .. .|. .|| ..| . . .... . .......| . ..|.| .| ||.|||
adeepvlyGd..ikv.tlvaeeeledwvirelkiekekeerkvrqyhftsWpdhgvPektk.tlldfvrtvreaiektaskrPivvhCsaGvGRtGtfia
FETAHLSLHSeQATLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAE
.. .... . ..|.. . .|. | . |. .|. |... . .
ldrllqaiee.edyvdifgivaelReeRnllvqtekqYifihqcvld
|
|||||||||
| subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 180-459 | 1.3e-31 | 104.1 | In-house | 3-287 (302) | alignment | ||
Range on Protein: 180-459
Range on HMM: 3-287/302.0
TEEKKQKWLGL--AKRFVDE-DANIAANDFEQVVSYIPPSVTKHQFVKNMHKNRFADVICLDHSKVHLS--DSSYIHASYLELD-TQKRAILTQLPLPHT
.||.|.|| . ||..|.. |. ..|... . . . | ||..||. || .||. | |. ||..|| .|. .. ||.||| .
veeekekWveeeeakklvksldtaevkkefkkidtmkvdlekCkafkknlkknqsedvpildsnlvkleaepdsyvnaskvevPeltrsiilaQlpkvds
S---ADFWQMIIEQRVKCVLLLLTDSEYDSlGGDFVFP-RNQDFLNFEErsIRVGEfKRVEIMDGWV--LKVVSVSNGDYKS-FLHIHHYNAWPHNNIPg
. ..||.|. ..... | .|. . | . . .|| . .|...... ..| ..|| ... . . . . .| | . . . . |.....|
edsveeFWrmvfqekivsvvilvgeeelkk.tlselfpkksgdykeygk..mfvNn.rkVekaeeektryviEvlPegcsnsvlanvyvltnWkqkkvp.
NGSPKFVKQIWQLqsVLRKYSPSTPTVYMSLSGCGRAGTFALFETAHLSLHSEqATLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAEHILD
. .|.. .. .| . . .|| .| |.||||.| .| .|... . .. .|. | .| ..|.|. ..| |. .|.
vkyaeliktaakv..fakkikadentvivSknGaGRagafltlavaveklqkg.kepnikeivksiRsqRpravdslkQyvslyialllyikk
|
|||||||||
| subfamily_PTPN3_pd | Subfamily PTPN3 | 217-450 | 3.6e-31 | 103.1 | In-house | 33-268 (280) | alignment | ||
Range on Protein: 217-450
Range on HMM: 33-268/280.0
VTKHQFVKNMHKNRFADVICLDHSKVHLSDSS--YIHASYLELDTQK-----RAILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDSEYDSLGGDFVFPR
... . .|..|||. |.. |. .|.|..|. || |.|.... . | | || ||..|..|||||. ||... ...| | | .|.
isaarkpenlsknryrdilpydatrvklkesetdyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqksslivmlttlverGrvkChqyWPe
NQDFLNFEERSIRVGEFkrvEIMDGWVLKVVSVSNGDYKSFLHIHH--YNAWPHNNIPGNgSPKFVKQIWQLQSVlrKYSPSTPTVYMSLSGCGRAGTFA
..| |.. | |... . . .||. . ... . | .|.. | ||| ...| . | .|.. . ..... . . ..|.| .| ||.| .
tedeleygefsvkceke...detksyvlrelvlkdketkeerkilqlqylaWpdhgvPdd.sadflefvervrkl..rsgkeePvvvhCsaGigrtGvli
LFETAHLsLHSEQATLDLVKCLEMVRNGRIHACQNLTQFSFVY
|.||| | .. . .. . ..|. | |. .|. ||
lletala.lieaaepvypldivrtmrdqramlvqtasqykfvC
|
|||||||||
| subfamily_PTPN9_pd | Subfamily PTPN9 | 220-457 | 1.2e-30 | 101.6 | In-house | 37-290 (297) | alignment | ||
Range on Protein: 220-457
Range on HMM: 37-290/297.0
HQFVKNMHKNRFADVICLDHSKVHLSD------SSYIHASYLELDTQKRA-ILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDSEYDSLGGDFVFP-RNQ
. |..|||..||.|.|...|.|. | ||.|.... ||.| | || ||..|. |||.|. ||.| ... | | .| ..
sklranleknrytdvlcydetrvvlakvdedeasdyinanfvdGykqkkafiatqGplkktvsdfWrmvWeqevlvivmttrvvergrlkcgqyWpleee
DFLNFEERSIRVGEFKRVEIMDGWVLKVVSVSNGDYKSFLHiHHYNAWPHNNIPGNGSP--KFVKQIWQLQSVLRK-------YSPSTP-TVYMSLSGCG
. .| . |... | . | ||.. | ... .. | . . .|| .| ... ...... . |... | . || | | .| |
ssaefgdlsvsnveveeeedykvrvleiknvkteesrkvth.fqflsWPdyGvPssaaslldvlekvrekqalavkelgdewkghpsgPPivvhcsaGiG
RAGTFALFETAHLSLhSEQATLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAEHI
|.|||. .. . | |..|.|.|......|. | .. | |. | | . |.
rtGtfitldiclsrl.eevgtvdvvetvkllrtqrafsiqtpeqyefcylavleya
|
|||||||||
| subfamily_PTPN13_pd | Subfamily PTPN13 | 219-453 | 1.6e-30 | 101.3 | In-house | 31-265 (273) | alignment | ||
Range on Protein: 219-453
Range on HMM: 31-265/273.0
KHQFVKNMHKNRFADVICLDHSKVHLSDSS-YIHASYLELDTQK---RAILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDSEYDSLGGDFVFPRNQDFL
. . .|..|||. .|. |...|.|.|.. || ||.... .| ..|..| |||.| .|||||. ||... . .. .. | . . . .| ...
vgkkkenkdknryrnvlPydetrvklgdeggyinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvkchrywPesknkk
NFEERSIRVGEFkRVEIMDGWVLKVVSVSNGDYKSFLHIHHYN--AWPHNNIPGNgSPKFVKQIWQLQSVLRkysPSTPTVYMSLSGCGRAGTFALFETA
. ..| .|. .||.|.. . |.. . . .. | | .|| ..| . . .... . ..... . ..| | .| ||.||. ...
lkvsnrlevell.kvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPss.aaellqfvaevrrlqt...dagPivvhcsaGiGrsGtlitidvv
hLSLHSEQATLDLVKCLEMVRNGRIHACQNLTQFSFVYTLL
| | . . .|. . .. .|. | | |. ||| .
.lglierdkefdvkeivrklreqrqgvvqtkdqyifvykai
|
|||||||||
| subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 223-456 | 2.3e-30 | 100.6 | In-house | 7-241 (250) | alignment | ||
Range on Protein: 223-456
Range on HMM: 7-241/250.0
VKNMHKNRFADVICLDHSKVHLSDSS------YIHASYLELDTQ-KRAILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDSEYDSLgGDFVFPRNQDFln
.| .|||.||.| ||.|.| | .. || ||.|. .. | | || ||..| |||.|..|. .. ...| . .| . .| ..
pqnkeknryadiialdssrvvLekekgdkesdyinasflhgyderkafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqywPvekae..
fEERSIRVGEFKRVEIMDG--WVLKVVSVSNGDYKSFLHIHhYNAWPHNNIPGNGspKFVKQIWQLQSVLRKYSPSTPTVYMSLSGCGRAGTFALFETAH
. ...| ... | | .||. . .. | . ..| . .|| .| . . | .. . .... ..| . .| ||.|.| ..
.kyGdvtvsllskeefadytkrklklskakkaderivrqlh.fvvWPdkgvPeva..tavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidavl
LSLHSEQaTLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAEH
|. |. ..|. | ....|. |.|| . |.|..|||... .
erlkkek.vvdvfkvikvlrkdrphavesleqyvfvyeiilka
|
|||||||||
| subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 205-458 | 6.1e-30 | 99.4 | In-house | 25-281 (318) | alignment | ||
Range on Protein: 205-458
Range on HMM: 25-281/318.0
DFEQVVSyIPPSVTKH--QFVKNMHKNRFADVICLDHSKVHLS------DSSYIHASYLELDTQKRA-ILTQLPLPHTSADFWQMIIEQRVKCVLLLLTD
..|.. . .||.. | .|||.|... ||..|.|. .| || |.|.. ..|.| | .| |||.| |||.|. || . ...|
eyerlsr.seetvtslkslepvnkaknryanilaydhtrvkLqmlegeegsDyinanyidGyrrkkayiaaqaPlpetieDfWrmvWeqnsavivmltqe
SEYDSLGGDFVFPRNQDfLNFEErsIRVGEFKRVEiMDGWVLKVVSVSNGDYKSF--LHIHHYNAWPHNNIPGNGsPKFVKQIWQLQSVLRKYSpSTPTV
.| . .| .. .... ..| ..|| .. .||. ..|.. . .. . .|| .|| ...| .| .... . | ... .| . .|.|
eergkakvhryWPskgs.rsygk..lvvelkeeve.lsdyvlrefkvtrteeeesrqvrqyhytsWpdegvpesg.aslldlvrqvskaqqksg.agpiv
YMSLSGCGRAGTFALFETAHLSLHsEQATLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAEHIL
.| ||.|.| .. .. ..|..|. . ...|. | | |. |.|. | | .
vhCsaGvGrtGvfiavdillerik.aealvDvfqtvkqlreqrnlmvqtedqyefiydvlleala
|
|||||||||
| subfamily_PTPN23_pd | Subfamily PTPN23 | 225-455 | 1.2e-29 | 98.1 | In-house | 43-278 (288) | alignment | ||
Range on Protein: 225-455
Range on HMM: 43-278/288.0
NMHKNRFADVICLDHSKVHLSDS--SYIHASYLELDT--QKRAILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDSEYDSLGGDFVFPRNQD-FLNFEER
. .|||. |.. ||..|.| .| || ||... . | || ||. |..|||.|. ||... . .||. .| . | .| ... .|..
yseknrsrdilPyDhnRvklrgskDDYinAsfvkdlspgcPdfiatqaPlqstlnDFWlmvyeqkssviVmllskeelgkpkvdrYwPedkgetvkfgdl
SIRVGEFKRVEIMDGWVLKVVSVSNGDYKSFLHIhHYNAWPHNNIPGNGS--PKFVKQIWQ-LQSVlrKYSPSTPTVYMSLSGCGRAGTFALFETAHLSL
|. . . .. | . |||. .. || |. ....||. .| . .|.... . ...| . || | ..| ||.|.||| .| |
svtlksvretethvervlkletldadavksvshl.qltsWpelGvPasPetllqfldevesayeav..qrksktPlvvhCsaGvgRtgvfalvyaavrel
HSEQATLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAE
. .. ||... .. .|. | . |. .|. |.| |
ekgnglldiiqvvsrlreqRrfmvqekeqlkfsyeavle
|
|||||||||
| subfamily_PTPRA_pd | Subfamily PTPRA | 197-458 | 7e-28 | 92.5 | In-house | 29-296 (330) | alignment | ||
Range on Protein: 197-458
Range on HMM: 29-296/330.0
EDANIAANDFEQVVS-YIPPSVTKHQFVKNMHKNRFADVICLDHSKVHLS------DSSYIHASYLELDTQKR-AILTQLPLPHTSADFWQMIIEQRVKC
.|.. ..|. . . | .. . .|..|||. ... |.|.|.|| .| || ||... .| | .| |. .| |||.|| ||.
ddnklfreefnalPagpiqatlelaskeenkeknrvvnilPydfsrvilsvkeGveesdyinasfidGykekdkfiaaqGPkeetvedfwrmiweqksat
VLLLLTDSEYDSLGGDFVFPrNQDFLNFEERSIRVGEFKRVE---IMDGWVLKVVSVSNGDYKSFLHIHHYNAWPHNNIPGNGSPkFVKQIWQLQSVLRK
...| | . .| .. . . . . | . . .. . . | .. .. . . .. |...||. .| .. .| . ..... ..
ivmltelkerkeekcaqywP.deGlvtyGnirvevedetvlvdytvrkflvqqlpdatrekksrlvrqfhftswPdvGvPfepiG.mlkllkkvkklnqq
YSPsTPTVYMSlSGCGRAGTFALFETAHLSLHSEQaTLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAEHIL
.. . .|. | .| ||.||| ... ...|. .|. . .. .|. | . | . |. |.| | |. |
sag.pivvhcs.aGvGrtGtfivldavlervkaer.kvdvfefvkrlrlqrpqmvqtdeqyefiykvlleyyl
|
|||||||||
| subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 221-457 | 7.7e-28 | 92.4 | In-house | 37-276 (281) | alignment | ||
Range on Protein: 221-457
Range on HMM: 37-276/281.0
QFVKNMHKNRFADVICLDHSKVHL------SDSSYIHASYLE-LDTQKRAILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDSEYDSLGGDFVFPRNQDF
. .|..|||. ... |...|.. ... || |.... .. .|. | || |.|.. ..||||..||.|. . .. . | . | .| ..
kadenvlknrYsnivaYDatrvkvtpneenkntDYinanfvpgykgekeyiatqgPvPaslvafWqmvweqkvsaivmvtreieagklkChrYWPddnse
LNFEERSIRVGEFKRVEIMDGWVLKVvSVSNGDYKSFLHIhHYNAWPHNNIPGNGSpKFVKQIWQLQSVLRKYSPsTPTVYMSLSGCGRAGTFALFETAH
|.. . .. . .. . . ..|. . ..|. .. .. .| ||| . .| . . .... ..... .| . .| | .| ||.||. ....
lkygdvtvkstaeeekatyierkfkl.eresgetreveql.aytaWPdhGvPattk.ellefrkevlkltekktk.aplvihCsaGvGrtGtyialDrlv
LSLHSEQATLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAEHI
....|...||. .. .|. | | ..|..||| . . .
kaveaeleeldvkavvaelrkernlmvqtvvqyefvykavldal
|
|||||||||
| subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 217-460 | 8.8e-28 | 92.2 | In-house | 39-282 (288) | alignment | ||
Range on Protein: 217-460
Range on HMM: 39-282/288.0
VTKHQFVKNMHKNRFADVICLDHSKVHLSD------SSYIHASYLELDTQK-RAILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDSEYDSLGGDFVFPR
||. . .| .|||. ... .|. .|.| . . || |||.. . .| . | || ||..| |||... |.... .. | | . . .|
vtagrlavnakknRyrnilpyDekrvklkkleeeagaDYinasyidgekkkkkyiatqgPladtvndfWelvyenktstivmltelveggktkCeeYWPd
NQDFLNFEERSIRVGEFKRveiMDGWVLKVVSVSNGDYKSFLHIHHYNAWPHNNIPGNGSPkFVKQIWQLQSVLRKYspSTPTVYMSLSGCGRAGTFALF
... |. . . . | | .. .||. . . . .. ..| ||| ...| . | ... . |.. . . | . | ||.|||
adkpknyGsvtvtlveske...ledfvlrklllekkkteleitqyqylaWpdhgvPeskap.llellrqvkvanqad..tgpiivhCsaGvGrtgtFial
ETAHLSLHSeQATLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAEHILDN
... ... . ..|.. .. .|. | |.|.|. |.| |.. | ..
dalidavee.edyiDvagtvaklRkqRallvqtlkqYefiyevllslieed
|
|||||||||
| subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 194-480 | 1.1e-27 | 92.2 | In-house | 28-313 (319) | alignment | ||
Range on Protein: 194-480
Range on HMM: 28-313/319.0
FVDEDANIAANDFEQVVSYIPPsVTKHQ---FVKNMHKNRFADVICLDHSKVHLS------DSSYIHASYLEL-DTQKRAILTQLPLPHTSADFWQMIIE
.|.| .. .| .. .. .. . .| |||. ... |...| | | || ||... ... | .| ||. | ||||.|| |
dfdddltklevefrracklgvn.ladqtfanldqnkdknriinilafdknvvklerliGeefsdyinasfvtGyqrkdkyiaaqGPldntladfWrmiwe
QRVKCVLLLLtdseyDSLGGDfVFPRNQDfLNFEERSIRVgefKRVEIMDGWVLKVVSVSN-GDYKSFLHI--HHYNAWPHNNIPGNGSPkFVKQIWQLQ
... ..|| . .| . . . |. ..| . || . .|.. . .|. | | .| .|. ||. | .|. ... . ...
yncstivllt.....kdkcsq.ywplkiv.ikeerfkvkv...dsveetaeyvvrdielsedgkekdirkitqfhflGwpdvGvpdypsd.lmrlvkkvr
SVLRKYSPSTPTVYMSLSGCGRAGTFALFEtAHLSLHSEQATLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAE-HILdnGFCKLAIPKKPNDEKDKEK
. .| .. | .|.||.|.. .. . |. |. .|. . .. .|. | . |.|.|. |.|. | | |.. |.. .|.| | ... .
hltskenhranivvhcsaGvGrtGvyivld.vlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleehlf..ghsdvampdfpayleelsn
D
.
k
|
|||||||||
| subfamily_PTPN14_pd | Subfamily PTPN14 | 220-457 | 1.1e-27 | 91.8 | In-house | 44-296 (300) | alignment | ||
Range on Protein: 220-457
Range on HMM: 44-296/300.0
HQFVKNMHKNRFADVICLDHSKVHLSD-----SSYIHASYLELD---TQKRAILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDSEYDSLGGDFVFPRN-
. .| .|||| ||. ....|.|| . || || .. ... | .| ||..| |||||. || |. ...| . | ||..
aklpenaeknrfkdvlPyednrvelsptkenstgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivmlteeeedgkeksfkyfPkle
--QDFLNFEERSIRVGEFKRVEIMDGWVLKVVSVSNGDYKSFLHIhHYNAWPHNNIPGNgSPKFVKQIWQLQSVLRKYSPST-------PTVYMSLSGCG
.. ..|.. . . . . ||. . ..... .|. |. || ...| . .|.. . ..||| || . .. | . . | |
skkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhl.qytDWpdhgvPeD.vkgflsyLeevqsvrrktnseveskeskPPvlvhCsaGvG
RAGTFALFETAHLSLHSEqATLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAEHI
|.| | . .|. . ..|. | |...|. | . |.|.|. |||..| ...
rtGvlilsdlliatlehn.eeidikkvlarLreqrmllvqtlaqYkfvYkvlikyl
|
|||||||||
| subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 202-457 | 2.5e-27 | 90.8 | In-house | 25-283 (319) | alignment | ||
Range on Protein: 202-457
Range on HMM: 25-283/319.0
AANDFEQVVSYIPPSVTKHQFVKNMHKNRFADVICLDHSKVHLS------DSSYIHASYLELDTQKRA-ILTQLPLPHTSADFWQMIIEQRVKCVLLLLT
...|... . .... . .| .|||. ... |...| || .| || ||... .... | || || .| |||.|. |... .|..|
lekefkllkeavndtfdsaskeenkkknryqnilaydrtrvvlseldgvegsdyinasfidgyqerekfiatqaPlentiedfWrmvWeeessivvmltk
DSEYDSLGGDFVFPRnQDFLNFEERSIRVGEFKRVEIMDGWVLKVvSVSNGDY-KSFLHIHHYNAWPHNNIPGNGSpKFVKQIWQLQSVLRKYSpSTPTV
..| . ..|. ..| .. . . . | .. | . ||. ... . ..|..|| ...| .. .. . ... .| . | | |
lveklkvklkkywpe.enfeeyGrlivtleeeeeledyiirklkl.nkkssevetRevkhfqyteWpdhdvPekat.slldllkrirksrektq.sgPiv
YMSLSGCGRAGTFALFEtAHLSLHSEQATLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAEHI
| || ||| . | | .|...||. . ..| | |. |..|.| | | .
vhCsaGvGRtGtfivld.amlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyealleav
|
|||||||||
| subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 222-485 | 3e-27 | 90.8 | In-house | 22-282 (284) | alignment | ||
Range on Protein: 222-485
Range on HMM: 22-282/284.0
FVKNMHKNRFADVICLDHSKVHLS------DSSYIHASYLEL-DTQKRAILTQLPLPHTSADFWQMIIEQRVKCVLLLLtdseyDSLGGDfVFPRNQDfL
.| |||. ... |...| | | || ||... ... | || ||. | ||||.|| |... ..|| . . .| . .
ldqnkdknrighilafdknvvklerliGeefsdyinasfitGyqrkdkyiatqGPldntladfWrmiweyncstivllt.....kdkcsq.ywplkiv.i
NFEERSIRVgefKRVEIMDGWVLKVVSVSN-GDYKSFLHI--HHYNAWPHNNIPGNGSPkFVKQIWQLQSVLRKYSPSTPTVYMSLSGCGRAGTFALFEt
. |. ..| . || . .|.. . .|. | | .| .|. ||. | .|. ... . ... . .| .. | .|.||.|.. ..
keerfkvkv...dsveeseeyvvrdielsedgkekdirkirqfhflgwpdvgvpdypsd.lmrlvkkvrhltskenhranivvhcsagvgrtgvyivld.
AHLSLHSEQATLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAE-HILdnGFCKLAIPKKPNDEKDKEKDKENED
. |. |. .|. . .. .|. | . |.|.|. |.|. | | |.. |.. .|.| | ... .... .|
vlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleehlf..ghsdvalpdfpayleelsnksdfdd
|
|||||||||
| subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 217-460 | 4.3e-27 | 90.0 | In-house | 45-287 (297) | alignment | ||
Range on Protein: 217-460
Range on HMM: 45-287/297.0
VTKHQFvkNMHKNRFADVICLDHSKVHLS------DSSYIHASYLELdTQKRAILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDSEYDSLGGDFVFprN
|.... |..|.|..... | |.|.| || |. ||... ..| | || | . | ||||.|.....|. ...| |.| | . . .
vaekkv..nfeksRYkniLPydssRvkLaivnddpdsDyvnasfvkg.nkhrlittqmPmkatvadfWamvldeqvstivmlnddnerdkkcaryWs..d
QDFLNFEERSIRVgefKRVEIMDGWVLKVVSVSNGD--YKSFLHIHHYNAWPHNNIPG-NGSPKFVKQIWQLQSVLRKYSPStPTVYMSLSGCGRAGTFA
. .| . |. . . |. | . . ..|..|. . ... ... ||..... . ....| | ... . . . . | . |.| ||.| .
kgvttfGdvsvvl...lsvsereGfikrelevtkgkakarrvvkqyqfveWPdkaverkdsassllklisevrkdfsqnaeg.PllvhclaGvGrtgvll
LFETAhLSLHSEQATLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAEHILDN
. .. .. ..|. . ....|. | . | |..||| .. | .| .
tidsv.vaeakrekevdifglvkklrqerpylvqtkeqykfvyvavleallse
|
|||||||||
| subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 206-462 | 6.5e-27 | 89.2 | In-house | 16-275 (285) | alignment | ||
Range on Protein: 206-462
Range on HMM: 16-275/285.0
FEQVVSYIPPSVTKHQFVKNMHKNRFADVICLDHSKVHLS--DSSYIHASYLELDT--QKRAILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDSEYDSL
... |.|| .| . | ||.||| |.. ..| | | |||||.. . | | || ||| | .|||.|| .... ||.| | |
qdkikgymppnctytayeanpdlnryadvrcieetrvvlknhdrdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggve
GGDFVFPRN-QDFLNFEERSIRVGEFKRvEIMDGWVLKVVSVSNGDYKS--FLHIHHYN--AWPHNNIPGNGSPkfvkqIWQLQSVLRKYSPS-TPTVYM
. .| . . ..| . | . | | | . | .|. ..| | . | |.. | . || . | . | . .| ..| | .| .
kcalyypeklgevvkfgkyeitltecke.eaiagtilnaltvintedasseplymnhvqvpwwpdqlapedarp.....mielykwvkkvnpkekpicvh
SLSGCGRAGTFALFETAHLSLHsEQATLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAEHILDNGF
.| ||. || . | . . |. .... . .| |..| |. || |.| .| |... .|
csagvgrtatfvgidyatirim.enpniemldivremramrfqavqshmqflflyvvlmeyfigegv
|
|||||||||
| subfamily_PTPRG_pd | Subfamily PTPRG | 204-458 | 1.2e-26 | 88.1 | In-house | 23-288 (563) | alignment | ||
Range on Protein: 204-458
Range on HMM: 23-288/563.0
NDFEQVVSYIPPS---VTKHQFVKNMHKNRFADVICLDHSKVHLSD-----SS--YIHASYLE-LDTQKRAILTQLPLPHTSADFWQMIIEQRVKCVLlL
..||...| . .. ... | .| .||| ... |.|.|.||. .. || |.|.. .| | || ||..| |||.|| ||.|. . .
eefealqsetiskdldaehsqkpenkrKnRylnivaydrsRvklsplpgkkkklDYinAnyidGyqkskafiatqgplkdtfddFWrmiWeqnvaiiv.m
LTD-SEYDSLGGDFVFPRnQDFLNFEERSIRVGEFKRVEIMDG--WVLKVVSVSNG---DYKSFLHIHHYNAWPHNNIPGNGSPKFVkqIWQLQSVLrKY
.|. | | .|. .. ..... ... | ... . |.| . . .. |.. .|| || . | |. . .| .
itnlvergrrkcdvYWPk.desetygalqvtlieeevlalytvrtlviknlklkkkkqcdteklvrqyhytkWPdhgvPehslpvLi..fvkkssaa.nk
SPSTPTVYMSLSGCGRAGTFALFETAHLSLHSEQaTLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAEHIL
. |.| .| ||.||. ..| . ...|. . .. . | ..| | . |. |. |.. | | |.
aeaGPivvHcsaGvgrtGtyivldtllkqiqqen.avnvfgflkhiraqRnflvqteEqYiflhdalleaia
|
|||||||||
| subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 201-461 | 3e-25 | 83.5 | In-house | 29-283 (290) | alignment | ||
Range on Protein: 201-461
Range on HMM: 29-283/290.0
IAANDFEQVVSYIPPSV-TKHQFVKNM--HKNRFADVICLDHSKVHLSDS---SYIHASYLElDTQKRAILTQLPLPHTSADFWQMIIEQRVKCVLLLLT
.| . .|... |.| .. | || .|||. ||.| | ..| |.| |.|| |.. .. |||| .| | |.|.|.....| . .|
lakeyleklkpylpvqylerkifdkntefkknrykdvvcndktrvilkdGydGdyvhanyvk.GlkamfiltqGalkdtvidiwrmvlqekvaaivmlce
DSEYDSLGGDFVFPRN-QDFLNFEERSIRVGEFKRV-EIMDGWVLKVVSVSNGDYKSFLHIhHYNAWPHNNIPGNGspkfvKQIWQLQSVLRKYspSTPT
| . .| . . | | | .. | . . . .| | . .| . . |. . .|| . .. . .. .||| | |
liedGkakceqyypekeGevltfGeitvlcseeddkdaniikktlsvrdkdsGkehklkhl.kikswpdksvalst.....lallrtlrilrka..sGpv
VYMSLSGCGRAGTFALFETAHLSLHsEQATLDLVKCLEMVRNGRIHACQNLTQfsfvYTLLAEHILDNG
| .| ||.|||. |.. | . |||.. .|| |. . | .| | .| | .|| |
vvhcsaGiGrtGtfvaievglqill.dGkeldlldlvralrnsrlnsvqvdiq....ylalveilldlG
|
|||||||||
| 0049772 | (Phosphotyrosine protein) phosphatases II | 215-456 | 7e-25 | 83.8 | In-house | 36-279 (314) | alignment | ||
Range on Protein: 215-456
Range on HMM: 36-279/314.0
PSVTKHQFVKNMHKNRFADVICLDhSKVHL-----SDSSYIHASYLelDTQKRAILTQLPLPHTSADF----------WQMIIEQRVKCVLLL-------
.... ....|..|||. |... | . |.| |.|.||.|||. |. .. | || ||..| || |.|.... .. .
ltilvadlflnrdknryldilpad.nrvilpglpvsgsdyinasyv..dgflkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivmsrdevl
----------------LTDSEYDslggDFVFPRNQDFLNfeersirvgefkrveimdgwvlkvvSVS--NGDYKSF-LHIHHYnawphnNIPGNGSPkFV
|. ... .. ......|. .. . ... .. ... ..|... |
adelsrLdaAlgKtpllildgng....neptaadlellk.........................eelydpelferlgikylri......pvpDgsap.ll
KQIWQLQSVLRKYSPSTPTVYMSLSGCGRAGTFALfeTAHLSLHSeqaTLDLVKCLEMVRNGRI-----HACQNLTQFSFVYTLLAEH
...... ....... .|.. .|.||.|||.. .| | .. ..| ..||.||. | .. ..| |. |.. | |.
edfdeflefieeadkggpvlvHCkaGkgRtgtfvv..aaylmkll...gvsleealedvrlkRpinpnpgfieqleqyefilealley
|
|||||||||
| subfamily_PTPN6_pd | Subfamily PTPN6 | 221-457 | 1.5e-24 | 81.5 | In-house | 50-297 (306) | alignment | ||
Range on Protein: 221-457
Range on HMM: 50-297/306.0
QFVKNMHKNRFADVICLDHSKVHL-----SDSSYIHASYLE---LDTQKRAILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDSEYDSLGGDFVFPRNQD
. ..|..|||. .. ||..| | ..| || |.|.. ...|. | || |..| .|||.|. .. . .... .. | .| ...
akpenkeknryknilPfDhtrvilkepsvpgsdyinanyikkevkgsdksyiatqgclettvsdFWrmvwqensrvivmttkevErgkekCarYWPdeee
FLNfeERSIRVGEFKRvEIMDGWVLKVVSVS---NGDYKSFLHIHHYNAWPHNNIPGNGSP--KFVKQIWQLQSVLRKYsPSTPTVYMSLSGCGRAGTFA
. .|.| . . . .. ..|. .||| ... . .. .|...|| ...| . . .|.... . |. |.. . |.| .| || |||
kee..yGkisvtnvse.ksladYilRelsvskkkkkkeerevfqyhfksWPdhgvpkdpgavLdfledvnrkqeeleea.eagpivvhCsaGiGRtGtfi
LFETA--HLSLHSEQATLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAEHI
. .. .. . .| .|. |. ..||. | | .|. |||. ....|
viDillkliekkgldadidiqklvksvreqrsglvqteqqykfvykaikkyi
|
|||||||||
| 0041856 | (Phosphotyrosine protein) phosphatases II | 225-459 | 2.1e-24 | 81.5 | In-house | 1-173 (182) | alignment | ||
Range on Protein: 225-459
Range on HMM: 1-173/182.0
NMHKNRFADVICLDHSKvhlsDSSYIHASYLELDTQK-RAILTQLPLPHTSADFWQMIIEQRVKCVLLLLtDSEYDSlggdfvfprnqdflnfeersirv
|..|||. |... ||| |..||.|... . | |.|| ||..| |||..|. |....... | . |.
nldknrysdilpydhsr....dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt.eelywp.......................
gefkrveimdgwvlkvvsvsnGDYKSFLHIHHYNAWPHNNIPGngSPKFVKQIWQLQSvlrkysPSTPTVYMSLSGCGRAGTFALFEtahL---Slhseq
... . ..| || ...| ..... | . .. .. |.. |.||.||... |
.....................ellerlgiqylylpwpDhgvpd..ldelldfieevle......eggpvlVHCsaGvgRtgtlvaay...lmkkl.....
aTLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAEHILD
..| .....||. | ...... |. |.. .| |..|
.gvsleeavklvrsrRpgmvitpnqyfflqlallellll
|
|||||||||
| subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 219-456 | 5.3e-24 | 79.7 | In-house | 43-278 (315) | alignment | ||
Range on Protein: 219-456
Range on HMM: 43-278/315.0
KHQFVKNMHKNRFADVICLDHSKVHL------SDSSYIHASYLELDTQKR-AILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDSEYDSLGGDFVFPRNq
. ..| .|||. ..| |.|.|.| ..| |. |.... ..|| | .| |.. . |||... |. . ...| | . . .| .
vakkienkqknryiniiaydksrvqlpllendphsdyvnanfidGynkkrryiaaqgpnvasvkdfwrlvfeedigkivmltnlvegekrkaekywpdk.
dFLNFEErsIRVGeFKRVEIMDGWVLKVVSVSNGDYKSFLHIHHYNAWPHNNIPGNGSPkFVKQIWQLQsVLRKYSPsTPTVYMSLSGCGRAGTFALFET
. . . | | | |. . . . .|| || . || .|| ..| | ... | . . . .. | .. | .| ||.||| ...
.kviyGk..itvt.rkseevnteytvrtlsvvfgdnirevvqlhytswpdmgvpkytip.lmnlirtvk.qhhtnsv.gaivvhcsaGvGrtGtfitlda
AHLSLHSEQAtLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAEH
.. |.| .|. . .. ||. ||.. | . |. |.| | |
vldqaeaena.idvynfitgvrqnrikmvqvaeqyqfiydallet
|
|||||||||
| subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 200-458 | 7e-24 | 79.5 | In-house | 23-289 (325) | alignment | ||
Range on Protein: 200-458
Range on HMM: 23-289/325.0
NIAANDFEQVVSYIPPSVTKHQFVKNMHKNRFADVICLDHSKVHLS------DSSYIHASYLELDTQKRAI-LTQLPLPHTSADFWQMIIEQRvKCVLLL
. |..|. . | . . . .|. |||| .|. ||.|.| | .| || ||||. | .| .| ||..| |.|..... | |...
dgfahefgllpsddgiakkvamkpenkaknrfknvvaldksrvvletkkddpssdyinasylrddkkkdvflaaqaPltatindlWrlvldWr.csvvvv
LTDSEYDSLGGDFVFPRN-QDFLNFEERSIRVGEFKRVEIMDGWVLKVVSVSNGDYKSfLHIHHYNAWP---HNNIPGNGSpKFVKQIWQLQSVLRK-YS
| . . .|.. . .| ... . . ||.| |..|. .| .. .. .|. .. | ... . ... ..
lneldlgkdrcavywpkemgksktfGglevklrtieeisdyvhrvldvkqvkkGetrs.vkqfqlqswddmGvqkrpatli.silqlvkavservtantk
PSTPTVYMSLSGCGRAGTFALFETAHLSLhSEQATLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAEHIL
||| . .| ||.|.|. . .| . |.. .|. . .. .|. | . |....|. |.| ..
astpilvhcsaGvGrtGvfislysalakv.ieesrvdifgfvkklrkdrpsmvetvdqyiliyealveaym
|
|||||||||
| subfamily_PTPRK_pd | Subfamily PTPRK | 224-458 | 1.8e-23 | 77.9 | In-house | 42-278 (314) | alignment | ||
Range on Protein: 224-458
Range on HMM: 42-278/314.0
KNMHKNRFADVICLDHSKVHLS----D--SSYIHASYLELDTQKRA-ILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDSEYDSLGGDFVFPRNQDFlnF
.| .|||. |.. |.|.| | | | || |.... .. .| | || ||..| .|||... ... ....| | . .| . . .
enreknrsgdilaydrsrvflitidgdpssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasivmltelvevgrvkClkyWPedtev..y
EerSIRVgEFKRVEIMDGWVLKVVSVSN--GDYKS--FLHIHHYNAWPHNNIPGNGSpKFVKQIWQLQSVLRKysPSTPTVYMSLSGCGRAGTFALFETA
. |.| |. ..|. | .. .|.. .. .. .. .||. ..| . ..| . .... . ..| ..|.||.||| ..
g..dikv.elvetellaelvvrifrveklargqeeirevrqfqflgWpdhdvPvsat.gllklvrrvkksqee..eaGrivvhCsaGaGrtGtfiaidiv
hLSLHSEQATLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAEHIL
| . .. ..|. .. .|. .. . |. |.| . | |
.ldmieregvvdvfnavktlrsrkvnmveteeqykfiydvileacl
|
|||||||||
| subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 221-457 | 2.9e-23 | 77.2 | In-house | 16-264 (270) | alignment | ||
Range on Protein: 221-457
Range on HMM: 16-264/270.0
QFVKNMHKNRFADVICLDHSKVHLSD------SSYIHASYLE--LDTQKRAILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDSEYDSLGGDFVFPRNQ-
..... . ||.||.. ...| |.. . || | |.. . .|. | .. ||| | .||.||.|..|...... | . .| ..
eaargkklnRyadiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepk
DFLNFEERSIRVGEFKRvEIMDGWVLKVVSVS-NGDYKSFLHiHHYNAWPHNNIPGNGS-----PKFVKQIWQLQSVLRKYSPSTPTVYMSLSGCGRAGT
. ...|. |.| . | ..|..|. . . .|. . .| ..||.|| . .| . . .| . ... . .. . ..|.. | ||.||
ekvkledgkikvlalse.ekeegyiltrlrleekgeerrlvH.fwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcsaGvgRtGt
FALFETAHLSLHsEQATLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAEHI
. . ..| |. |. .|... .| .|. |. | |. |.| ..|..
lialDiavrlLe.etkkvdvlaiieelRkdRmalvqhpeqyeflykavveya
|
|||||||||
| subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 221-458 | 3e-23 | 77.2 | In-house | 40-278 (315) | alignment | ||
Range on Protein: 221-458
Range on HMM: 40-278/315.0
QFVKNMHKNRFADVICLDHSKVHL------SDSSYIHASYLE-LDTQKRAILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDSEYDSLGGDFVFPR-NQD
. |..|||. ... ||...| | || || |||.. .|..| | .| ||. . |||.|.....| . .. .| | . .| . |
retinfkknryknilPldsarvkleviddsPdsdyinasyiksvdddkayiasqgPlkasvddfwrmvlqekvttivmvtkkqegdkikcrqywPdrkad
FLNFEERSIRVgeFKRVEIMDGWVLKVvSVSNGDYKSFLHIHHYNAWPHNNIPGNGSpKFVKQIWQLQSVLRKYspSTPTVYMSLSGCGRAGTFALFETA
.| . .. . .. || . |. . ... . . .... ||.. .. . | ..| | .... .|. . . ..| ||.| . .
svefGsikvel..lsleadtdgvarkl.vtrkseesrtvtqfqftewPdkGvdkqts.sllklikevkadngkk..efsllvhcsaGvGrtGvvisidev
hLSLHSEQATLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAEHIL
.. .. ..|. . ....|. |.. | ...|.| . |..|
.vaqikrtrsvdvfnfvknlrakrpylvqteeeyafiydavledll
|
|||||||||
| subfamily_CG7180_pd | Subfamily CG7180 | 223-460 | 3.9e-23 | 76.5 | In-house | 40-293 (296) | alignment | ||
Range on Protein: 223-460
Range on HMM: 40-293/296.0
VKNMHKNRFADVICLDHSKVHL------SDSSYIHASYLELDTQKRA-ILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDSEYDSLGGDFVFPRNqdFLN
.|. ||| .|. |. .| | ..| || |.| . ..|.. | |. | .| .||... .. ...| | .. . ... .. .
kenreknrdvkvvPyDynRvvLekldGeeksdYinavyvdsflkkkeyivteapkketvdefWrlvydeeisavvvLtktfdfakmypsywpnks..keq
FEERSIRVGEFKRVEIMDGWVLKVVSV--SNGDY-------KSFLHIHHYNAWPH-NNIPGNGSpKFVKQIWQLQSVLRKY---SPSTPTVYMSLSGCGR
. | . . | | . . .|.. . .. . .. .. |. ...| . ... . . ... .| |.| .| | .|
ygeifveiveekqyanlkirtfkltkkivalteqekqvkaetRivklfqlteWeledkvPlstn.alielrrrvrlwrekvdedpeegPvvvvssdGasR
AGTFALFEtAHLSLHSEQATLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAEHILDN
.| . . | | | ... .|. . . ..|. | . .| ... ..| .| |..| |
sGvylaid.anlelvekeeevdvFeavktlrrsRpqLvenveeYkyiYdvlleavlcn
|
|||||||||
| subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 193-459 | 8.1e-23 | 75.9 | In-house | 9-279 (307) | alignment | ||
Range on Protein: 193-459
Range on HMM: 9-279/307.0
RFVDEDANIAANDFEQVVSYIPPSVTKHQFVKNMHKNRFADVICLDHSKVHLS----DSSYIHASYLELDTQ-KRAILTQLPLPHTSADFWQMIIEQRVK
| .| . ..|... . | .|| . | | .|||. || | |.... . | |||| || . .. |. | .| || | .|| |.|...|.
rtldkgvqalvdefrvlakktpegvtveafsantdknryqdvkcqdkgrivvkfdglasdyihanylgiaikpkkficaqgplentqysfwamaiqekve
CVLLLLTDSEYDSLGGDFVFPRNQDF-LNFEE--RSIRVGEFKRVEI-MDGWVLKVVSVSNGDYKSFLHIHHYNaWphNNIPGNGSPKFVKQIWQLQSVL
.|..| | . . .| .. | | | ..| | .. .. | ...| .. . |.|.. | .| | .| |. | .
svimlckvielakikceqywpleegqklvfgeapntisvanlgakklapdedlinvttlkvdwaqksrtiqhlq.w..enwpdrgvpqinltainlleav
RKysPSTPTVYMSLSGCGRAGTFALFETAHLSLHSEQATLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAEHILD
| | | .| ||.|| . . . |. | .| .|. | .| |. |. ... .| |. |.
ry..dtnpvvvhcsaGvGrsGtivaislvqdkmiaGinckdmkklveelrsqrhyaiqteaqylylhrvlleyfle
|
|||||||||
| subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 205-457 | 9.3e-23 | 75.8 | In-house | 27-283 (305) | alignment | ||
Range on Protein: 205-457
Range on HMM: 27-283/305.0
DFEQVVSYiPPSVTKHQFVKNMHKNRFADVICLDHSKVHLS------DSSYIHASYLELDT-QKRAILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDSE
....... . |. .. .| .|||..... ||.....|. || || |||.. .|. |..| ||..| ||||..|.| .|. ...| |
qykslyee.eesidvgkkeankaknrlkeitlldddriiltekeslddsdyinasyvdgykrkkkyivaqgPlkntvadfWrliveekvstivmltklve
YDSLGGDFVFPRNQDF-LNFEERSIRVGEFKRveiMDGWVLKVVSVSN--GDYKSF-LHIHHYNAWPHnnipgNGSPKFVKQIWQL-QSVLRKYSPS--T
. .| .. .|.| |. . ..| . ... . ...|. .| .| . .. || .| |.| . .| . | .... . .
ggkdkCrqYWpesktekkefgefsvelksekt...asdyieRklkisiededkesrtvlqyqltdWPd.....hGvpqfatsllslikrvqkdqkkdkgv
PTVYMSLSGCGRAGTFALFETAHLSLHSEQaTLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAEHI
| . | ||.|.| . | |. |. ..|. . | .|. |. . |.| |. |.. |.| |
pllVhCsagvgRtGvfiavdialerlkkEe.vvdvfevlkqlRskrmkmvqtldqYvflhdaldeli
|
|||||||||
| subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 218-456 | 1.1e-22 | 75.5 | In-house | 21-267 (274) | alignment | ||
Range on Protein: 218-456
Range on HMM: 21-267/274.0
TKHQFVKNMHKNRFADVICLDHSKVHL-------SDSSYIHASYLEL-DT-QKRAILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDSEYDSLGGDFVFP
... .. .|||. ... ..|.| | .||||| | |. |. .| . || |||.| ||||.|| ...|. ...| .| . ||
eeldvfgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneqkCavyfP
RNQDF-LNFEERSIRVGEFKrVEIMDGWVLKVVSVSNGDYKSFLHIHHYNAWPHNNIPGNGSpKFVKQIWQLQSVLRK-YSPSTPTVYMSLSGCGRAGTF
..|. .. . . . | . ... .. ..... . .. . | .|| .. | . . .... . . .. .. . .|.| .| ||.| |
daedyeiserygdveikvek.iverndysvrklvlkylerersvkhywytdWPdhksPddan.tlldlvleveesreeenaklapvvvhCsaGiGrtGcf
ALFETAHLSLHSEQaTLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAEH
. | |. |. ..|..| .| | |. |. ... |...
iaisiavrqlreei.vvdvlkivcnlrldrGGmvqtseqyelihralcly
|
|||||||||
| subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 223-463 | 2.3e-22 | 74.1 | In-house | 46-293 (305) | alignment | ||
Range on Protein: 223-463
Range on HMM: 46-293/305.0
VKNMHKNRFADVICLDHSKVHLSDS---SYIHASYLELDT-QKRAILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDSEYDSL-GGDFVFPRNQDFLNFE
.. .|||. || |||. .|.| . |||| |. | || | || || .| |||| | ....|. ...| | . .. ...| |.||
aqeagknrykdvgcldnnrvklegpwpheyihanyvstptnpkrfictqaplektcadfwymclqdkveaifmlcnllekgakkcleyfaskdkdvlefe
ERSIRV-------GEFKRVEIMDGWVLKVVSVSNGDYKSFLHIHHYNaWphNNIPGNGSPKFVKQIWQLQSVLRKYspSTPTVYMSLSGCGRAGTFALFE
|. .. ...| .. . | . | | .| .. ... || | .. | | | | .| | |.| .| ||.|. ..|
ekgqkisvkfessvtlkfrkdakakvtetvlviegpgekarkvthyh.w..idwpdrgvpaadlailellekarps..kgpivvhcsagigrtgsvvmle
TAHLSLHSEQATLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAEHILDNGFC
| . | | | | .|. | . | .|. ||. .. ........
yildqllagqiiedtdkilqkireqrnnsiqtdaqylfvhqvilnyfrkkkll
|
|||||||||
| subfamily_Ptp69D_pd | Subfamily Ptp69D | 205-457 | 2.8e-22 | 74.2 | In-house | 27-286 (307) | alignment | ||
Range on Protein: 205-457
Range on HMM: 27-286/307.0
DFEQVV-SYIPPSVTKHQFVKNMHKNRFADVICLDHSKVHLS------DSSYIHASYLE-LDTQKRAILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDS
..|.. . |. | . . | |||. |.. |. .| |. ||.|| ||... . .|. | | |. | |||.|| || |. . .| .
eyekLeareidkstkvsekkenalknRyedikafDktRvkLkkingkedsdYinasfikgykekkkfiaaqdPveatigDfWRmiaeqevtlivmlsnlt
EYDSLGGDFVFPRNqDFLNFEerSIRVgEFKRVEIMDGWVLKVVSVSNGD-----YKSFLHI--HHYNAWPHNNIPGN--GSPKFVKQIWQLQSVLrkys
|.. . .| . | ... .| | .. . | .. .. . ..||. . . .. .||..|. ..| | |...|. .|..
eknrkkcakYWpie.devqyg..dilv.klvseekhsdyiiReldvskkkeesgevedsrkvvqyhytgWkDskvPevargllklieqvrelykln....
pSTPTVYMSLSGCGRAGTFALFETAHLSLHSEQaTLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAEHI
.| | | ||.|.| .. |. |. ..|... .|. | |.| |..|.| |....
.rsPivvhCsaGvgrsgifvaldsllqqlkaed.kvdifetvkdLrsqRnllvqsleqYvflyralldys
|
|||||||||
| subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 220-458 | 6.6e-22 | 72.3 | In-house | 38-277 (515) | alignment | ||
Range on Protein: 220-458
Range on HMM: 38-277/515.0
HQFVKNMHKNRFADVICLDHSKVHL------SDSSYIHASYLE-LDTQKRAILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDSEYDSL-GGDFvFPR-N
| | .|||. ... .| ..| | .| |. |||.. .|..| | .| |.. . |||.......| . .. .| | | . .|
aqeeinfkknryknilPydsvrvklevindnPhsdyfnasyipsfdndkayiasqgPnkasvddfWrlvlqenvttiamvtklkegdkikcgky.WPdkp
QDFLNFEerSIRVGEFkRVEIMDGWVLKVVSVSNGDYKSFLHIHHYNAWPHNNIPGNgSPKFVKQIWQLQSVLRKYSpsTPTVYMSLSGCGRAGTFALFE
| ..| ||.| .| | . . . | || . .|.. ||.. .| . . ..| | .... .|. | . ..| ||.| . .
gdsvkfG..sikvelv.sleactggikrkltvlkgddsrtvtqfhfteWPdkGvpkh.tssllklikevkadhgqyt..hpliihcsaGvGrtGvvisid
TAhLSLHSEQATLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAEHIL
.. . ..|. . .. .|. | . | |..|.| . |..|
sv.vahakttrmvdvfnfvtnirqkrpylvqtqeqyafiygavledll
|
|||||||||
| subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 219-460 | 1e-21 | 72.2 | In-house | 37-274 (288) | alignment | ||
Range on Protein: 219-460
Range on HMM: 37-274/288.0
KHQFVKNMHKNRFADVICLDHSKVHLSDSS--YIHASYLELDTQ-KRAILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDSEYDSLGGDFVFPRNQDFLN
..|..| ..|. .. . | ..|.||| . ||.| . .| | .| || | .|.|..|. |. ...| | . || ..
idsfianptrdryenlprcditrvklsddpdfyiaanvvssakykrrlicaqaPlngtieelWkmllesdveyivmlcellekGkeksaeyfPsklGeka
FEERSIRVGEFKRVEIMDGWVLKVVSVS-NGDYKSFLHIHHYNAWPHNNIPGNGSPKFvkqiwQLQSVLrkYSPSTPTVYMSLSGCGRAGTFALFETAHL
| | ||..| .. .. .| .|. | .. | |.. |... .| | . . .| || | | | .| | ||.||..| |
rigrlctvvkkkradidklvkvsllriskegeekvivkilhlleWdddgvPenylspl.....rllevl..kslqkPivvhssaGvGrtgtlililiale
SLHSEQaTLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAEHILDN
|| .. | . . |. |. | .| | |. .|. .. |..|
slrldd.flgirsllaklreerfkaiqtemqylyvhrcvleelllk
|
|||||||||
| 0051429 | (Phosphotyrosine protein) phosphatases II | 245-457 | 1e-21 | 73.3 | In-house | 2-225 (272) | alignment | ||
Range on Protein: 245-457
Range on HMM: 2-225/272.0
SDSSYIHASYLELDTQ----KRAILTQLPLPHTSADFWQMiIEQRVKCVLLLLTDSEYDSLGGDFVFP-----------RNQDFLNFEERSIRVGEFKRV
. |.||.|... .. .| .... |||.| ||||.. |...|... | ...|...|. |.. | . . .. .... ...
plsgyiNardvggygrvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseell
EIMDGWVLKVVSVSNGDYKSFLHIHHYNAWPHNNIPGNGSPKFVKQIWQlqsvlrkyspSTPTVYMSLSGCGRAGTFALFETAHlSLHSEQATLD-----
. . ..| .. ... . ... || .|| ..| . ...... . . | .. .|..| ||... |... .|
ldyilrellltlllsagearevmhlhytdwpdhgvpqeallellellld..........ggpvlvHCsaGkdRTGtvvalllll.lgvsletivddYllt
---LVKCLEMVRNGRIHACQNLTQFSFVYTLLAEHI
| ...|..| | .| |. .|. |.| |.| .
nlyleeaveelraqrpgavqteeqylflyeallell
|
|||||||||
| subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 198-457 | 1.5e-21 | 71.3 | In-house | 18-279 (439) | alignment | ||
Range on Protein: 198-457
Range on HMM: 18-279/439.0
DANIAANDFEQVVSYIPP-----SVTKHQFvkNMHKNRFADVICLDHSKVHL------SDSSYIHASYLEL-DTQKRAILTQLPLPHTSADFWQMIIEQR
. .| . ||.. | |. |.. ... . |||. || .||..| | | || | |.. ..| | || | .|. |||...||..
kqeifkeifekinstspdyaciaslaaqey..dqtknrykdvgafdhtrvtlqeipgvphshyinanyikGyyddklyiatqgpkkettddfwrlviekk
VKCVLLLL--TDSeYDslggdfVFPRNQDFLnFEERSIRVGefKRVEIMDgWV---LKVVSVS-NGDYKSFLHIHHYNAWPHNNIPGNGSpkFVKQI-WQ
. .. | .| | .| ... . . ..|| . .|. . .| .||. ... . . || |||..|.| . | .| .
tvtivmltnlves.yk......ywpsdaevc.ygdiavrvd..rnielpn.yvirgfkvfnerdttekertvlqfhyiawpdknvpaqas..hvldflra
LQSVlRKYSPSTPTVYMSLSGCGRAGTFALFETAHLSLHSEQaTLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAEHI
..| | | .| ||.|| .. | |..|. .|. ....|. | . |.| |. |.| . | |
insa.ndkeeygpvvvhcsagvGrtGtiialdialeqlklen.kvdikgivkvlrkqrkqmvqalcqyvfiynavledi
|
|||||||||
| subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 202-454 | 2.2e-21 | 70.8 | In-house | 9-266 (281) | alignment | ||
Range on Protein: 202-454
Range on HMM: 9-266/281.0
AANDFEQVVSYIP---PSV--TKHQFVKNMHKNRFADVICLDHSKVHLSD-------SSYIHASYLELDTQKRA-ILTQLPLPHTSADFWQMIIEQRVKC
. .||.| .| .| || | . | .|||.... ||| |.|.| . |||| |. || |||| | | ||||.|| .. .
tlddfkqefsnlpgdppsdlctvfnqpvnnkknrylnipcldisrvqlkvkmpnknstdyihanyirspflkrgyiltqgpkketradfwrmiwqentta
VLLLLTDSEYDSLGGDFVFPRNQD-FLNFEERSIRvgeFKRVEIMDGWVLKVVSVSNGDYKSFLHIHHYNAWPHNNIPGNgSPKFVKqiwqlqsVLRKY-
...| | . |||| |.|.. |. .. . | . .| .. .. || ..|. | ..| .|||
ivmlcqfletnrekcaeyfprnahcclqfdklsvs...yedstvnkslvttrlnlsyegetrlithwlwkewpdwqvpes.sevmlk.......ilrkir
SPSTPTVYMSLSGCGRAGTFALFETAHLSLHSEQATLDLVKCLEMVR-NGRIHACQNLTQFSFVYTLLA
. ||| | .| ||.||. | | |.|| . |. . . .| || . | | |. ... .|
arstppvihcsagvgrsgtlmaveialqsihshftlpdikqivshlrvtgraasvqtlqqymliwkvll
|
|||||||||
| subfamily_PTPRN_pd | Subfamily PTPRN | 204-457 | 1.9e-20 | 67.8 | In-house | 33-292 (297) | alignment | ||
Range on Protein: 204-457
Range on HMM: 33-292/297.0
NDFEQVVSYIPPSVTK--HQFVKNMHKNRFADVICLDHSKVHLS------DSSYIHASYL-ELDTQKRA-ILTQLPLPHTSADFWQMIIEQRVKCVLLLL
...| ...| || . ||..||| ..|. |||.|.|. .| || || . . | .. | | || ||..| ||||||. || | .. |
kewealcayeaepstkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplastvadfwqmvweqGvvvivnlt
TDSEYDSLGGDFVFPRNQDFLNFEERSIRVGEFKRVE--IMDGWVLKVVSVSngDYKSfLHIHHYNAWPHNNIPGNgsPKFVKQ-IWQLQSVLRKysPST
. .| . . .| . . | | . .. . || . | . .. . |. .||....| . .| . . ... | |.
rleeegvkqckrywpdeGsevyhiyevhlvsehiwcddylvrsfylknlqts..etrt.vtqfhflswpeegvPas..aksllefrrkvnksyrG..rsc
PTVYMSLSGCGRAGTFALFETAHLSLHSEQATLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAEHI
| | . .|.||.|.. | . | .|.. || .|. | . . || |..| .|| .
pivvhcsdGaGrtGvyilidlvlnrllkGvkeidiaatlehlrdqrpglvktkdqfefaltavaeev
|
|||||||||
| PTPc_DSPc_SM00012 | 352-455 | 7.9e-20 | 66.4 | In-house | 3-105 (105) | alignment | |||
Range on Protein: 352-455
Range on HMM: 3-105/105.0
HIHHYNAWPHNNIPGNGsPKFVKQIWQLQSVLRKYSPSTPTVYMSLSGCGRAGTFALFETAHLSLHSEQATLDLVKCLEMVRNGRIHACQNLTQFSFVYT
. ||..||. ..| .. .... ....... .| . |.|.| .. |.||.|||....... .|..|. ..|. ......|. | ...|...|..|.|.
khyhytgwpdhgvPees.dsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylflyr
LLAE
|.|
alle
|
|||||||||
| subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 206-456 | 8.1e-20 | 65.9 | In-house | 12-258 (267) | alignment | ||
Range on Protein: 206-456
Range on HMM: 12-258/267.0
FEQVVSYIPP--SVTKHQFVKNMHKNRFADVICLDHSKVHLSDS--SYIHASYLEL-DTQKRAILTQLPLPHTSADFWQMIIEQRVKcVLLLLTDSEYDS
||.. . ... || .||. |.. |...| |... || |||.| |.. |.|| || | .||...|..|.| | ||| . |
felikkisdtsstisqsiaeknqernrlddnlpyddtrvilrtkeeeyinasyvegyktknafivtqdplkntitdfltvihdqkvp.vivlltkvftdn
LGgDFVFPRNQDFLNFEERSIRVGefKRVEIMDGWVLKVVSVSNGDYKSFLHIHHYNAWphnNIPGNGSPkFVKQIWQLQSVLRKYSPSTPTVYMSLSGC
. | |. . .... .. | | .. . . . . ...|. | || | | ..| .. . . . . | | |
ir.lfwPPkmgqakkyqdltvehs..lekeendyqiitlelkfknesahnvtlyyykkw...nintnnkp.ylkplfgilaknqlengnrPlvvacsdGv
GRAGTFALFETAhLSLHSEQATLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAEH
||.||| .. | .. ..|. . | .|. || . . .. ... ||||.
GrsGtflvidsq.leraktegvsdifdflrkirsqriglvdtkeryiyihellaey
|
|||||||||
| subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 218-458 | 2.7e-19 | 63.8 | In-house | 38-237 (392) | alignment | ||
Range on Protein: 218-458
Range on HMM: 38-237/392.0
TKHQFVKNMHKNRFADVICLDHSKVHL------SDSSYIHASYL-ELDTQKRAILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDSEYDslggdfvfprn
| | |..|||. ... .| ..|.| .|| |. |||. .|..| | .| | . . |||.|. ...| . .. | |
tvaqkeinlkknryknilpydsarvkleviddipdsdylnasyipsfdnekayiasqgpnaaslddfwrmvfqenvttiamvtklkegd...........
qdflnfeersirvgefkrveimdgwvlkvvsvsNGDYKSFLHIHHYNAWPHNNIPGNGSpKFVKQIWQLQSVLRKYSpsTPTVYMSLSGCGRAGTFALFE
.|| . .|. || ...| | ..| | .... .|. | . .| ||.| .
.................................kgddartvaqfhftewPdkdvpkhts.sllkfikevkadfGqyt..hpliihcsagvgrtgvvisid
TAhlSLHS-EQATLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAEHIL
. |. . .|... . .|. | . | |..|.| . | .|
sv..vahakktrmvdvfnfvtnirrkrpymvqtkeqyafiygavledll
|
|||||||||
| subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 192-460 | 7e-19 | 62.6 | In-house | 16-292 (305) | alignment | ||
Range on Protein: 192-460
Range on HMM: 16-292/305.0
KRFVDEDANIAANDFEQVVSYIPPSVTKHQFVKN------MHKNRFADVICLDHSKVHLS---DSSYIHASYLEL--DTQKRAILTQLPLPHTSADFWQM
.| .| . ..| .. | | .|. | | . |||..|| | |.| |.|. | |||| |. .|| | .| || .| .|| |
lraldvgvdklreefrglakytrpdmtqvafnanqsadiaitknryqdvpcqdqsavkldkpspsdyihanyvgcpmipekrficaqgpldqtidefwwm
IIEQRVKCVLLLLTDSEYDSLGGDFVFPRNQDFLNFEERSIRVGEFKRVEIMDG---WVLKVVSVSN-GDYKSFLHIHHYNAWPHNNIPgngspKFVKQI
.|...|. ...| | | .| | | | . |. . .. .. || | . ... || .|
viqnkveqivmlcktvelgklkcaqywpaaqgeklelksgivvenvsgskpmerdaeiqitllnltysgdqkmsvrhlqwtewpdrgvp.....pcklts
WQLQSVLRKysPSTPTVYMSLSGCGRAGTFALFETAHLSLHSEQATLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAEHILDN
.| | .| | | .| ||.|| | . .. . . . .|. | .. || |. |.. .. ...|..
lellsairg..skvpivvhcsagigrtgtivaieyilekiaenkpcppmpelvkalrdqrafsiqndvqylfihrvmlnyflek
|
|||||||||
| 0046846 | (Phosphotyrosine protein) phosphatases II | 244-454 | 7.8e-19 | 63.6 | In-house | 9-170 (176) | alignment | ||
Range on Protein: 244-454
Range on HMM: 9-170/176.0
LSDSSYIHASYLELDtqkRAILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDSEYDSLGGDFVFPRNQDFLNfeersirvgefkrveimdgwvlkvvsvs
|..||.|... . | | || |||.| |||..|. |.....|. |... |...|. . .|. ...
dldldyinanlilgs...rpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgi............................
ngdyksflhIHHYNAWPHNNIPGNgsPKFVKQIWQLQSVLRKYspsTPTVYMSLSGCGRAGTFALFEtahlsLHSEQATLDLVKCLEMVRNGRI-HACQN
... || ...| . . . .....|.. |.. |.||.||... | . |.. ..|..||. | .| |.
.........qylhlpwpDhgvpdl..elllellefirealkeg...gpvlVHCsaGigRtgtlvaay.....llelekglsveealalvreqRplgavqt
LTQFSFVYTLLA
| |.| .
peQyrflyefel
|
|||||||||
| subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 214-293 | 2.3e-18 | 60.8 | In-house | 41-126 (310) | alignment | ||
Range on Protein: 214-293
Range on HMM: 41-126/310.0
PPSVTKHQFVKNMHKNRFADVICLDHSKVHLS-D----SSYIHASYLELDTQKR-AILTQLPLPHTSADFWQMIIEQRVKCVLLLL
.|.| . . |.|||||..||.||| |.|.| | |||| |. . . | .| || || |||.||...| . .|||
dssltyeaykkymhknrysdvvcldtsrvklkidksryedyihanyvktnylrstficsqgplqhtiidfwrmifqeraesilllc
|
|||||||||
| subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 210-455 | 5.8e-18 | 59.9 | In-house | 32-276 (287) | alignment | ||
Range on Protein: 210-455
Range on HMM: 32-276/287.0
VSYIPPSVTKHQFVKNMHKNRFADVICLDHSKVHLSD--SSYIHASYLELD-TQKRAILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDSEYDSLGGDFV
|. . .|| .| .|||..... | .| | . || |.... .|. |... |. .| .||..| ...|. ...| . | |
vtqredevthniasqnkdknRltqilvpdnyrvllkgehpdyinavfidgykekkafiiaesPmfntarnfWkliddrnvtaivmlcqekendeevcyqy
FPRNQDfLNFEERSIRVGEFKrveIMDGWVLKVVSVSN---GDYKSFLHIHHYNAWPHNN-IPGNGspKFVKQIWQLQSVLRKYSpSTPTVYMSLSGCGR
.| .. . . | .|.. . . ...|.. . . | | . | .. ... .|. . .. . .| . || . |. | . ||
Wpeeks.vvlGeyniellnee...vnagyierklevknknkagdkqqvkqyqitnWdstgkvtepq..tillvieemyktqrkrg.ntsivvhCsdtvGr
AGTFALFETAHLSLhSEQATLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAE
...| .|. .. ..|... |. | . .. | .|. |.. .. |
samfcaaattinkc.kteGviDvfqvlksqriqkpgsvqtveqykfindivle
|
|||||||||
| subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 201-458 | 6.9e-18 | 59.5 | In-house | 10-267 (283) | alignment | ||
Range on Protein: 201-458
Range on HMM: 10-267/283.0
IAANDFEQVVsyIPPSVTK-HQFVKNMHKNRFADVICLDHSKVHLSDS--SYIHASYLE----LDTQKRAILTQLPLPHTSADFWQMIIEQRVKCVLLLL
. . .... .|. .. . .| .|||. ... | .|.| .|| |... . .|. | .| || .| |||.|. .... ....|
lfrevlkrls..vpdldadiasadenkrknrnqeivpadqwrvelksesrdyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekitaivmlt
TDSEYDSLGGDFVFPRNqDFLNFEERSIRVGEFKRveiMDGWVLKVVSVSN-GDYKSFLHIHHYNAWPHNNI-PGNGSPKFVKqIWQLQSvLRKYSPSTP
| .|.. .. | . . . . .. | . . . . || | . || .. .. .|| . ...| |.. |. .|
klqedlrikCsqyWPkr.GsedyGeftvtlrkett...snsfiikelllrvnssakstlllahyqvidWleygeqaiinslvk.fnkvis.lqteskkgP
TVYMSLSGCGRAGTFALFETAHLSLHSeQATLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAEHIL
| .| ||...| .. . . .. .|. . ....|. |. | |.| |. .|..| |. |
ivvhCstgiGrtavfiaasasvkdalt.esvvdvfavvkimreqrmmavqtldqyklvhelvleqal
|
|||||||||
| subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 215-455 | 8e-18 | 59.3 | In-house | 36-281 (290) | alignment | ||
Range on Protein: 215-455
Range on HMM: 36-281/290.0
PSVTKHQFVKNMHKNRFADVICLDHSKVHLS------D--SSYIHASYLE-LDTQKRAILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDSEYDSLGGDF
.|| .| ..||||... | .. | | .||.|.|.. .|. |.|| |...| .|||..| ...| ....|.. | ..
htvtvgltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgykekkqyiatqgpvsntlvdFWkliwqekvtiivmltniieegkvkCqq
VFPRNqDFLNFEERSIRVGEFKRVEIMDGWVLKVVSVSNGDYKSFLHIHHYNAWPHNNiPGNGSPKFVKQIWQLQSVLRKYSpSTPTVYMSLSGCGRAGT
.| . | ...| ||.. . . .. . |.| . .....|. .. .. .|... . . .| . . || |. | . ||...
YWpds.dtkaygefsikllneetlneyierklevknknsagakqsvtqyqitnwdstg.kvtnpqtillvieemyktqrkrg.ntsivvHCSdtvgrsav
FALFETAHLSLHSEQaTLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAE
| .|. ..|. |... |. | . | |. ...... .
fcaaattinkckteg.vidvfqvlksqRiqkpgsvqtvqqyqgifqivlt
|
|||||||||
| subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 225-451 | 1e-17 | 59.1 | In-house | 7-234 (239) | alignment | ||
Range on Protein: 225-451
Range on HMM: 7-234/239.0
NMHKNRFADVICLDHSKVHLS------DSSYIHASYLE-LDTQ-KRAILTQLPLPHTSADFWQMIIEQRvKCVLLLLTDS-EYDSLGGDFVFPRNQ-DFL
| |||.|... |||.| | | || |||| | | | || . .| |||.|. ..| .||...|| | .| . .
nkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqer.rcvivmltglieghkkkchqywpdstskyc
NfeersIRVGeFKRVEIMDGWVLKVVSVSN--GDYKSFLHIHHYNAWPHNnipgnGSPKFVKQIWQLQSVLRKYS--PSTPTVYMSLSGCGRAGTFALFE
| .|| ... |.. .... . .|. . ... .|. || . | |.. . |. . | | . | | .| ||.|.| . .
n.....lrvt.lrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdk.....gvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvid
tAHLSLHSEQATLDLVKCLEMVRNGRIHACQNLTQFSFVYT
| | .| |.|... .. .|. | | | |. |..
.amlrqakkqktvdifnyvkairedrphmvqtseqyvfihl
|
|||||||||
| subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 225-451 | 1.2e-17 | 58.9 | In-house | 8-235 (239) | alignment | ||
Range on Protein: 225-451
Range on HMM: 8-235/239.0
NMHKNRFADVICLDHSKVHLS------DSSYIHASYLE-LDTQ-KRAILTQLPLPHTSADFWQMIIEQRvKCVLLLLTDS-EYDSLGGDFVFPRNQ-DFL
| |||.|... |||.| | | || |||| | | | || . .| |||.|. ..| .||...|| | .| . .
nkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqer.rcvivmltglieghkkkchqywpdstskyc
NfeersIRVGeFKRVEIMDGWVLKVVSVSN--GDYKSFLHIHHYNAWPHNnipgnGSPKFVKQIWQLQSVLRKYS--PSTPTVYMSLSGCGRAGTFALFE
| .|| ... |.. .... . .|. . ... .|. || . | |.. . |. . | | . | | .| ||.|.| . .
n.....lrvt.lrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdk.....gvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvid
tAHLSLHSEQATLDLVKCLEMVRNGRIHACQNLTQFSFVYT
| | .| |.|... .. .|. | | | |. |..
.amlrqakkqktvdifnyvkairedrphmvqtseqyvfihl
|
|||||||||
| 0043147 | (Phosphotyrosine protein) phosphatases II | 246-450 | 2.3e-17 | 58.7 | In-house | 4-154 (172) | alignment | ||
Range on Protein: 246-450
Range on HMM: 4-154/172.0
DSSYIHASYLELDTQ-KRAILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDseydslggdfvfprnqdflnfeersirvgefkrveimdgwvlkvvsvsn
.| ||.||||.| .| | || ||..| ||||.|. |. ..... | .
gsdyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltel.................................................
gDYKSFLHIHHYNAWPHNNIPGNGSPkFVKQIWQLQSVLR---KYSPSTPTVYMSLSGCGRAGTFALFETAHlslhseqATLDLVKCLEMVRNGRIHACQ
| | ... . . ..| .| | ...... . .. ||. |.. |.||.||... . |.| .....||. | .|.|
.lydpellerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml.......lglsleeavalvrekRpgavq
NLTQFSFVY
| | |.|
npsqyrfly
|
|||||||||
| subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 223-455 | 2.9e-17 | 57.4 | In-house | 36-275 (287) | alignment | ||
Range on Protein: 223-455
Range on HMM: 36-275/287.0
VKNMHKNRFADVICLDHSKVHLSD-----SSYIHASYLELDTQ-KRAILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDSEYDSLGGDFVFPRNQDFLNF
. ...|||.|||. .|...| || |.|| | |. |. .. | .| |.. | |||....|.|. |... . | | .| .. .
laavkknryadvlPiddtrvllsaegelGsdyinanyvasytddeafiaaqgPiaatvrdfwravletrsasvitmtreveearlkcykywPerevPmrv
EERSIRVGEFKRVEImDgWVLKVVSVSNGDYKS--FLHIHHYNAWPHNNIPGN--GSPKFVKQIWQLQSVLRKYSPSTPTVYMSLSGCGRAGTFaLFETA
|. . ... | . . . . . . . . .. .. .|| . .. | .|| .. | . |. | | | | ||.|.. | .
GGysvvlldydikeP.e.ygvralrlidletrearvvkqldllswPdkvlaPtavglirfvldvkqhielardasevGPlvvhddvGiGrsGil.latlv
HLSLHSEQATLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAE
.| . .| . . .|. | | |. ..| |.
lvsrledlGrvdvaavvirlreyraalvqavvqlrllyealvt
|
|||||||||
| subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 224-452 | 6.4e-17 | 56.6 | In-house | 2-234 (237) | alignment | ||
Range on Protein: 224-452
Range on HMM: 2-234/237.0
KNMHKNRFADVICLDHSKVHL----SDSSYIHASYLE-L-DTQKRAILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDSEYDSLGGDFVFPRNQDFLNFE
.| |||...... |||.| | |.| || |.||. . | |. | .| || . |||||. ... ...| | . | .| .. .
enkiknrygnivaydhsrvvlkgagsgsdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpstdqpaayg
ErsIRVGEFKRVEIMDGWVLKVVSVSNGDYKSFLHIH--HYNAWPHNNIPGNGSP--KFVKQIWQLQsvlRKYSPSTPTVYMSLSGCGRAGTFALFEtAH
. | |. |. | | .. . .. | || .. .||.. .| . . .| |.| . .. | |.| . .| ||.| | . . |
v..ltvslkkkeefsdytvrslllskrltlkevrlihqyqftswpdrgvpqqtaallrfrkniinrs...phvsesgpwiihcsagvgrtgiflvid.am
LSLHSEQATLDLVKCLEMVRNGRIHACQNLTQFSFVYTL
| |. .|. . . . . | . | |. |..
lrqakekkvvdiynyvysieedrpyiiqtkdqyvfihqt
|
|||||||||
| 0036282 | (Phosphotyrosine protein) phosphatases II | 247-450 | 1.6e-15 | 52.7 | In-house | 2-163 (174) | alignment | ||
Range on Protein: 247-450
Range on HMM: 2-163/174.0
SSYIHASYLELDTQ-KRAILTQLPLPhtsadFWQMIIEQRVKCVLLLLTDSEYDSLGGDFVFPRnqdflnfeersirvgefkrveimdgwvlkvvsvSNG
|.||.||.| | .| |..| ||. ||.|. |.....|. ||. | .. . .|.
sdyinaspldlsyitprliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe.................................lre
DYKSFLHIHHYNAWPHNNIPGNGSpkFVKQIWQLQSVLRKySPSTPTVYMSLSGCGRAGTFALFETAHLSLHseQATLDLVKCLEMVRNGRIHACQNLTQ
|.. . . ..| || .. | . . . .....| . .|. |.. |.||.||... . |. . . | .. . ..|. | ...|. |
dlerlgiqylylpwpDhgvpdlsi..llefvkfveealse.dpggpvlVHCsaGvgRtGtlvaaylmlrgll..eslvdaldlvrelRlqrpgmvqtpsQ
FSFVY
. |.|
yrfly
|
|||||||||
| subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 215-465 | 2.3e-15 | 51.1 | In-house | 33-284 (312) | alignment | ||
Range on Protein: 215-465
Range on HMM: 33-284/312.0
PSVTKHQFVKNMHKNRFADVICLDHSKVHLS--DSSYIHASYLELDTQK-RAILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDSEYDSLGGDFVFPRNQ
. |.| ||. .. | | . |. . |||| .. . |. | . || || |.. |||. . ...|| . | |
sdsectaflkfkdlnrypniqcwdrgrftlagdenfyihanfvkictkperfvctqgplentcthfwqlalslgstsiillcgfvedgsekcakyisdiv
DFLNFEERSIRVGEFKRVEI-------MDGWVLKVVSVSNGDyKSFLHIHHYNAWPHNnipgnGSPKFVKQIWQLQSVLRKYspSTPTVYMSLSGCGRAG
|...|. . .|| . ||||| . |. .| | . . .|| | | . .| | ..| | . .| ||.|
gfvdledhrvyteycteieiggkskdkithrvlkvvvkatgq.esklnhyqwaswpdh.....gmpdscdtalrllsavkkd..kkpviahcsagvgrtg
TFALFETAHLSLHSEQaTLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAEHILDNGFCKL
|.|| |. .| . .. . . ..|. | . . . |. .. . | . .|. |
tlaliesmiaalrhpr.kqnvkdsfvllrkdrarsvrvfpqyvyalrcvleflyskglykr
|
|||||||||
| 0049260 | (Phosphotyrosine protein) phosphatases II | 261-450 | 3.1e-15 | 51.6 | In-house | 9-143 (152) | alignment | ||
Range on Protein: 261-450
Range on HMM: 9-143/152.0
KRAILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDSEYDSLGGDFVFprnqdflnfeersirvgefkrveimdgwvlkvvsvsngdyksflhihhynAWP
...| || |.|.| ||||.|. |. ..... | ...| . |. .. . .
fefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi..................................................qyl
HNNIPGNGSPKFVKQIWQLQSVLRK--YSPSTPTVYMSLSGCGRAGTFALFETAHlslhseqATLDLVKCLEMVRNGRIHACQNLTQFSFVY
| ..| .| |.. . .| ...| ... |.. |.||.||... . ..| .....||. | .|..| | |.|
hlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml.......lgvsleeavalvrekRpgavpnpgqlrfly
|
|||||||||
| subfamily_ptpA1_pd | Subfamily ptpA1 | 213-407 | 5e-15 | 50.1 | In-house | 34-247 (418) | alignment | ||
Range on Protein: 213-407
Range on HMM: 34-247/418.0
IPPSVTKH-QFVKNMHKNRFADVICLDHSKVHLS------DSSYIHASYLELDTQKRAILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDSEYDSLGGDF
. || | . .| |||..... ..|..|.| | || | |.. |. | || ||| | ||||.|. |.|.. ...| .|| . |
vgpsetsegdkkhntsknrytnilpvnhtrvqlkkiqdkegsdyinanyidgaypkqfictqgplpntiadfwrmvwenrcriivmlsresencrikcdr
VFPRNQ---DFLNFEERSIRVGEF--KRVEIMDGWVLKVV----SV-SNGDYKSfLHIHHYNAWPHNNIPGNGSP--KFVKQIWQLQSVL-RKYSPSTPT
.| . .| . . .| . . ||... ... . .|. . . ..|. || ||| | .... | . | . |
ywpeqiggeqfsiygngnevfgtysvelveviqdpereiitrnirltfegetrd.itqyqyegwpdhnipdhtqpfrqllhsitnrqnqiipssdrnvpi
VYMSLSGCGRAGTFA
. .| ||.|||.
ivhcsagvgrtgtfc
|
|||||||||
| subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 217-449 | 1.1e-14 | 48.9 | In-house | 42-273 (301) | alignment | ||
Range on Protein: 217-449
Range on HMM: 42-273/301.0
VTKHQFVKNMHKNRFADVICLDHSKVHLSDS---SYIHASYLELDT-QKRAILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDSEYDSLG-GDFVFPRNQ
.|. . . .|.|. | | .. |.. . ||| ... . .| | || ||. || ||| |.. |. . .| |. ... . .
itesyaylpkdkhryptvPckPstavevivdGkrvPihanwiptsGhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkis
DFLNFEERSIRVGEFKRVeIMDGWVLKVVSV--SNGDYKSFlHIHHYNawpHNNIPGNGSPKFVKQIWQLQSVLRKYspSTPTVYMSLSGCGRAGTFAlf
. |. . .|.. . . . . . . . . | | |.... . ||. ... . .| || ....| ...| | | .| ||. .|
ekldigrfkikiknkeli.lnkkiskrtlevedstgkfatr.tvthyq...ysewtdrgvPkshaelfdlmelvkks..ekPivvhcsaGiGrsvafi..
ETAHLSLHSE-QATLDLVKCLEMVRNGRIHACQNLTQFSFV
| |. . | . |..| . |. .|. | .. |. .|. ..
gteylareveadptieltealkhlrehrwngvqtnsqlywm
|
|||||||||
| subfamily_egg_pd | Subfamily egg | 224-455 | 2.5e-14 | 47.7 | In-house | 39-268 (307) | alignment | ||
Range on Protein: 224-455
Range on HMM: 39-268/307.0
KNMHKNRFADVICLDHSKVHLS------DSSYIHASYLELDT-QKRAILTQLPLPHTSADFWQMIIEQRVKCVLLLltDSEYDSLGGDFVFPRN-QDFLN
|..| | | | | |.|.| .||| ... . ||.| || | |||.|. ...|. ...| .| .| .. .|. .| |
nnlekarskrvhckdssrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvddfwrmvfqeevqyivml..tsrkeserceyywpkaesdslv
FEERSIRVGEFKRVEIMDGWvLKV--VSVsNGDYKSFLHIHHYNaWPHNNIPGNGSPkfvkqiwqLqSVLRKY-SPSTPTVYMSLSGCGRAGTFALFETA
. |.|. .| . | ..| . . | . ... |.. . || || | |||| |.|.| . |. .|.|. |.|
tvpGslrienlkvdskadpl.frvtklkl.vGgddeerflehwq.gdvnnssdvysp........l.rvlrklrnlskpvvvqdilGvskaatlvaieia
HLSLHSEQATLDLV-KCLEMVRNGRIHACQNLTQFSFVYTLLAE
||| | || .. ..| | . . .. ||| |..
llsllrGpitkslvlravvflrlrrrlsvesvllylfvyrlvlf
|
|||||||||
| subfamily_eak_pd | Subfamily eak | 186-458 | 6.6e-14 | 46.0 | In-house | 12-306 (332) | alignment | ||
Range on Protein: 186-458
Range on HMM: 12-306/332.0
KWLGLAKRFVDEDANIAANDFEQVVSYIPP-SVTKHQFVKNMHKNrFADVICLDHSKVHLSDS-----SYIHASYLEL-DTQKRAILTQLPLPHTSADFW
||. . | .. . | | ... | . |... . ......| ... |. .|.|. | || || .|. . .. ||| .. ||
kwilinknhiwnrinqrinivadlddyqrllsisetarleavnrn.vvkivpydrylvrltssqlnrlGyinaslaefsevGrkyiltGiasedkvfafw
QMIIEQRVKCVLLLLTDSEYDSLGGDFVFPRNQ-DFLNFEERSIRVGEFKRVEIMDGWVLKvVSVSNGDYKsfLHIHHYNAWPHNNIPG-----------
||..||. ... || | | . | || . . |.| . || . .|.. |. .|. | .. .. ... | ..|
qmvleqkspaivqlledvelkleksdkyfpdktreelkfGildverkefvkrniletrlle.lskGnethr..vlhykvfGwtettlpkyedflalrkvm
--NGSPKFVKQI-WQLQSVLRKYSPSTPT---VYMSLSGCGRAGTFALFETAHLSLHSEQATL-DLVKCLEMVRNGRIHACQNLTQFSFVYTLLAEHIL
| .... |.|.|.|| . |. . | | |||.| . . . . . | . . . |.. |||. | ||.| .. ...|
kevGvlllivmksallsstlkkyihtppsfapiiqsarGsaraGvfvvidllirlidnkkknlysvedlilkvkskrihsvlvalqhsfiyeivldyll
|
|||||||||
| subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 208-299 | 1.7e-11 | 38.2 | In-house | 78-175 (244) | alignment | ||
Range on Protein: 208-299
Range on HMM: 78-175/244.0
QVVSYIPPSVTKHQFVK-NMHKNRFADVICLDHSKVHLSDSS----YIHASYLE-LDTQKRAILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDSEYD
| . ||| | | | .||| . . .| ..| || .| || ||.. | |||| || || |||.|..|. |. ...| . | |
qniirpdpsvmkdafnpnnswknregaglpfdfnrvplskgsmgntyinasfvgclgrtaeyiltqhpladtsmdfwkmmlerhvnvlvvlgsveeed
|
|||||||||
| 0044763 | (Phosphotyrosine protein) phosphatases II | 245-455 | 2.4e-11 | 39.1 | In-house | 16-169 (178) | alignment | ||
Range on Protein: 245-455
Range on HMM: 16-169/178.0
SDSSYIHASYLEldtqKRAILTQLPLphtsADFWQMIIEQRVKCVLLLLTDSEYDSLGGDFVFPRNQDflnfeersirvgefkrveimdgwvlkvvsvsn
| ||.||. . .|..|| ||..... |. ..... | .. |. |. | .|.. .
ersdyinaseil....pglylgslpp....addlellkelgithivnlteelelgflkcdpywpeeag................................
gdyksflhihhyNAWPHNNIPGNGSPKFVKQIWQLQSVLRKY--SPSTPTVYMSLSGCGRAGTFALFETAHLSlhseqaTLDLVKCLEMVRNGRIhACQN
. | .||..| | ...... .... .. |.. | ||.||... . |.| ...|.||. | ...|
............iqylhipipDhgvpdllehflefvefieealdekggpvlVHCsaGvgRsgtlvaaylmkkl......glsleeaielvrerRp.ivpn
LTQFSFVYTLLAE
| ..| . .
pgqlrqLyefelr
|
|||||||||
| 0051082 | (Phosphotyrosine protein) phosphatases II | 247-452 | 2.4e-11 | 38.9 | In-house | 3-148 (151) | alignment | ||
Range on Protein: 247-452
Range on HMM: 3-148/151.0
SSYIHASYLEldtqKRAILTQLPLPhtsaDFWQMIIEQRVKCVLLLLTDSEYDslGGDFVFPRNQdflnfeersirvgefkrveimdgwvlkvvsvsngd
|.||..||.. . .... ||. ||.... |. .|... | .. |.. .|...
sdyinfsyvt....gglyrsggpla....dflellkelgiktivnlrseeerg..ycpeylpelg...................................
yksflhiHHYNAWPHNNIPGNGSPKFVKQIWQLQSVLRKySPSTPTVYMSLSGCGRAGTFALFETAHLSlhseqatLDLVKCLEMVRNGRIHACQNLTQF
... .| . | | | . ... .. ..|.. .. |.. .|.|| ||... .| ..| ..||..| | .. | .||
.......ievlhipildwpdpglplsfdavleflellld.kkngpvlvHCsaGkgRTGtlvalylmllg.......vsleealeeyrlkrpgvvqpnqqf
SFVYTL
|..
lfqlfa
|
|||||||||
| subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 206-292 | 6.1e-11 | 36.4 | In-house | 18-116 (347) | alignment | ||
Range on Protein: 206-292
Range on HMM: 18-116/347.0
FEQVVSYIPPSVTKHQFVKNMHKNRFADVICLDHSKVHLSD-----------SSYIHASYLELDT-QKRAILTQLPLPHTSADFWQMIIEQRVKCVLLL
|.. .| |. .| .. |.. ||| || | ..| || .|| ||.. .| .| |||| |||.| |||.|. .| |. .
denlanyspskftsvewekslsknrskdvklidatrvvlspeksknsraddvetyinashikfdnaskeyiltqyplpdtvrdfwkmvsvtkvtqvvti
|
|||||||||
| subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 223-299 | 8.6e-11 | 36.1 | In-house | 45-142 (350) | alignment | ||
Range on Protein: 223-299
Range on HMM: 45-142/350.0
VKNMHKNRFADVICLDHSKVHLS--------------DSSYIHASYLELD-------TQKRAILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDSEYD
|. . |||. ... .||.|.| . || |.||.| .. . | || ||| | ||...|.. || .| | .| |..
velfaknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdveln
|
|||||||||
| subfamily_Cele-PTP-5_pd | Subfamily Cele-PTP-5 | 248-457 | 3.7e-10 | 32.9 | In-house | 99-309 (346) | alignment | ||
Range on Protein: 248-457
Range on HMM: 99-309/346.0
SYIHAS---YLELDTQKRAILTQLPLPH---TSADFWQMIIEQRVKCVLLLLTDSEYDSLGGDFVFPRNQDFLNFEERSIRVGEFKRVEIMDGWVLKVVS
.|.| .. .. ... |..||| . ||| || ..... | |.. | .. | . | . ..|.
ayvhlvvlyfvifqfehklivaqlpqmenesfvedfwymiyqeqihlvylmvpddklkntttslfndenggyqytgkmfinnrradvsgdpkeytievlp
VSNGDYkSFLHIHHYNAWPHNNIPGNGSPkFVKQIWQLQSvlRKYSPSTPTVYMSLSGCGRAGTF--ALFETAHLSLHSEQATLDLVKCLEMVRNGRIha
| | ..||. | | . | . | .| | |. | | .. .|| ||||| .| ||. | | ....| . | | .
egnsds.vicqvhhhapwkhlqqppktlp.iikmihqfls..ekqvqnagvcvvslfgcgracsfigalyainqlnngiepniceimknikqqrpggv..
cQNLTQFSFVYTLLAEHI
. ..|.. .|... ..|
.esfaqyasiyaivfdyi
|
|||||||||
| subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 241-451 | 4.9e-10 | 34.0 | In-house | 41-253 (290) | alignment | ||
Range on Protein: 241-451
Range on HMM: 41-253/290.0
KVHLSDsSYIHASYLELDTQKRAILTQLPLPHT-------SADFWQMIIEQRVKCVLLLLTDSEYDSLGGDF----VFPRNQD-FLNFEERSIRVgefKR
. ...| ||||... | |||| |. .. .|| |. . .|| | | .| .. ..| .| . . |.|. ... |
gkrfnd.dyiHAnrvtcpnglrliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCakYvpesvgeelkfkgltvkC...ks
VEIMDGWVLKVVSVSNGDYKSFLHIHH-YNAWPHNNIPGNgspkfVKQIWQLQSVLRkySPSTPTVYMSLSGCGRAGTFALFETAHLSLHSEQATLDLVK
| |. . . | .| . | |. .. | . |.. . | . .| . .. || . | | ..| . . . . . |..
kekeddvetRelvvkfddeeeftvtHsllkgWnklnvqed.....tktllsliqkvk..asktpvivHcvdGiSrsAalaaiilgyQkiaetsgsvkled
CLEMVRNGRIHACQNLTQFSFVYT
|...|. | .| .. ....||
vlkalrkqralaitsalelafvda
|
|||||||||
| subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 233-307 | 4.1e-09 | 30.2 | In-house | 75-152 (349) | alignment | ||
Range on Protein: 233-307
Range on HMM: 75-152/349.0
DVICLDHSKVHL-SDSSYIHASYLEL---DTQKRAILTQLPLPHTSADFWQMIIEQRVKCVLLLlTDSEYDSLGGDFVF
|| .|. . || | ||.| ...|. | || ||| | ||...|. ..|| || | .|.. ||. ..
kvikastsesdsgklddyinanylkltrisvekkyiatqaPlPstvddfykvillngvklvlsL.nddkelslekcdiy
|
|||||||||
| subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 218-297 | 7.9e-09 | 29.6 | In-house | 33-121 (301) | alignment | ||
Range on Protein: 218-297
Range on HMM: 33-121/301.0
TKHQFVKNMHKNRFADVICLD--------HSKVHLSDSSYIHASYLELD-TQKRAILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDSE
| . .| . ||| .. .| .....|. .|| |||.. .|. | .| |. .| .|||..|..... .. . |
tvglseenkalnrfknitvyddnriilkpkpnldlcqreyinasyidgysekkkfiaaqgpmkktlvdfWrliwqekpvsivmvtnlke
|
|||||||||
| subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 265-457 | 1.9e-08 | 28.7 | In-house | 39-221 (255) | alignment | ||
Range on Protein: 265-457
Range on HMM: 39-221/255.0
LtqlplphTSADFWQMIIEQRVKCVLLLLTDSEYDSLGGDFVFPRNQDF-LNFEERSIRVGEfkrveIMDGWVLKVVSV--SNGDYKSFLHIHHY--NAW
| | . |.|.|. .. . | .| | . . || ..| | ... .. . . . ||. . . |. | ..|| . |
l.......tvdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdeklkladvnvtttk.....ssadvvlrtleitstlgekkkthtvkhysykGW
PHNNipgngSPKFVKQIWQLQSVLRKyspSTPTVYMSLSGCGRAGTFALFETAHL----SLH-SEQATLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLA
. .| .|. ..| .. | |. | . | . .| ||. .|.| | .. ||. .| . || .. || .|. | | .. |..| ..
iekn.....aPelareilnilkvvrd...sksvvvhCstGiGrsaafvlaelvyqkmirsldttetveldylslleelrskrkraihtPlqlafsilmvl
EHI
. .
dlv
|
|||||||||
| subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 222-291 | 6e-08 | 26.9 | In-house | 30-106 (297) | alignment | ||
Range on Protein: 222-291
Range on HMM: 30-106/297.0
FVKNMHKNRFADVICLDHSKVHL----SDSSYIHASYLELDTQK---RAILTQLPLPHTSADFWQMIIEQRVKCVLL
..|||. |.. | ..|.| ... || | |. . .. . ||.| || | |||... || |. . .
rnsslrknryrdilatddtrvkllrviterdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivm
|
|||||||||
| 0048179 | (Phosphotyrosine protein) phosphatases II | 339-451 | 8.5e-08 | 27.6 | In-house | 33-139 (144) | alignment | ||
Range on Protein: 339-451
Range on HMM: 33-139/144.0
VVSVSNGDYKSFLHIHhYNAWPHNNIPGNGSPKFVKQIWQLQSVLRKY-SPSTPTVYMSLSGCGRAGTFALFETAHlslhseQ-AtLDLVKCLEMVRNGR
|...... .. || . . | ..|..| | . ... .. .... ... |.. |.||.||... . |.| ..|..||. |
vinlteeyepeflere.giqylhlpwpDhgvpdllellleflefieealeeggpvlVHCsaGvgRtgtlvaaylmk......klg.lsleealalvrsrr
IHACQNLTQFSFVYT
.|..| |. |..
pgavpnpgqlrfLle
|
|||||||||
| subfamily_Cele-PTP-12_pd | Subfamily Cele-PTP-12 | 217-291 | 1.4e-07 | 25.3 | In-house | 26-106 (332) | alignment | ||
Range on Protein: 217-291
Range on HMM: 26-106/332.0
VTKHQFVKNMHKNRFADVICLDHSKVHLSD----SSYIHASYLELDTQKRA-ILTQLPL-PHTSADFWQMIIEQRVKCVLL
| .|..|| || . |.|||.| |. . ||... ..| | |..| |. || ||.|. |.. .|.
ntydkflnnmdmnriphlycfdhsrvelapqdgkddfynaswvdgyskksayifaqapfndhteyvfwrmvserkpsmilv
|
|||||||||
| 0048076 | (Phosphotyrosine protein) phosphatases II | 347-454 | 1.4e-07 | 26.8 | In-house | 41-140 (145) | alignment | ||
Range on Protein: 347-454
Range on HMM: 41-140/145.0
YKSFLHIHHYNawpHNNIPGNGSPKFVKQIWQLQSVLRKYSPS-TPTVYMSLSGCGRAGTFALFETAHLslhseqATLDLVKCLEMVRNGRIHACQNLTQ
. . .. .| . ..|..| | . ...... .... .. |.. |.||.||... .| ..| ..||.||. | .|..| |
ellerlgiqyl...ylpwpDhgvpdllellleflefieealkeggpvlVHCsaGvgRtgtlvaaylmll......lgvsleealelvrsqrpgavpnpgq
FSFVYTLLA
. |.| ..
lrflyefel
|
|||||||||
| subfamily_Sponge-PTP-4_pd | Subfamily Sponge-PTP-4 | 240-299 | 2.3e-07 | 25.2 | In-house | 6-66 (130) | alignment | ||
Range on Protein: 240-299
Range on HMM: 6-66/130.0
SKVHLSDSSYIHASYLEL-DTQKRAILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDSEYD
| . ||.||.. | . . .||| || || |||.|..|. | ...| . | |
evsrlqgntyinasfvGllgrtaeylltqhpladtsmdfwkmmleryvnvlvvlgsveeed
|
|||||||||
| subfamily_CG42327_pd | Subfamily CG42327 | 225-387 | 3e-07 | 24.4 | In-house | 28-198 (319) | alignment | ||
Range on Protein: 225-387
Range on HMM: 28-198/319.0
NMHKNRFADVICLDHSKVHLS------DSSYIHASYLE--LDTQKRAILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDSEYD-SLGGDFvFPRNQDFLN
|.|...|. | ...| | . |..|||. |.. | .| .| .|.|||... ||. . .. | || .. .| .. |
skdksrvinvvPlPetrvvlqrigdddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlselGikvcaey.lPtketldn
FEERSIRVGEFKRVEIMDGWVLKVVSVSNGDYKSFLHIHHY-NAWPHNNIPGNGSPkFVKQIWQLQSVLRKYS
. .| |. | ... . . . | . .. || |.. ..| . .. .. . . .| |. ||
tslyGdilvtlkgrevkdryaistlllkrvdkeesrelthywykwleaevPaeeaa.liamllevrsslksys
|
|||||||||
| subfamily_Cele-PTP-3_pd | Subfamily Cele-PTP-3 | 220-322 | 1.1e-06 | 20.4 | In-house | 24-122 (275) | alignment | ||
Range on Protein: 220-322
Range on HMM: 24-122/275.0
HQFVKNMHKNRFADVICLDHSKVHLSDSSYIHASYLELDTqKRAILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDSEydsLGGDFVFPRNQDFLNFEER
..|..| .||||..| |.|. . .. ..||. . ...| | |.||. ... |. |. |.. | || || . | |.
erfirngeknrftnvtcfdeildrenqeffvhantfrtpy.gnflisqapndstnadhlhllwiynvqtvvclvlpee...aggyfvpkegetftsfqky
SIR
|.
qik
|
|||||||||
| subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 259-451 | 1.3e-06 | 22.7 | In-house | 3-198 (199) | alignment | ||
Range on Protein: 259-451
Range on HMM: 3-198/199.0
TQKRAILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDSEYDSLGGDFVFPRNQDFLNfEERSIRVGEfKRVEIMDGWVLKVVSVSN--GDYKSFLHIHHY
.|.| | || || .| ||||||. | .... | | .| . . |. | | . ... .. ..| | | ||
gqrryiatqhplretmadfwqmvwetgsghivmvnddqknkeadypfywpttesgtg.kygslsvtt.ktittkpdytitaliltnnttappstreishy
N--AWPHNNIPgnGSPKFVKQIWQLQSVLRKYSP--STPTVYMSLSGCGRAGTFALFETAHLSL-HSEQATLDLVKCLEMVRNGRIHACQNLTQFSFVYT
. .| . | || . . | .|| .| . | | .| | .. | | . .|| . .|. | | .. |.|
qftswkekttp..nvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiyq
|
|||||||||
| subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 259-451 | 1.4e-06 | 22.7 | In-house | 2-197 (198) | alignment | ||
Range on Protein: 259-451
Range on HMM: 2-197/198.0
TQKRAILTQLPLPHTSADFWQMIIEQRVKCVLLLLTDSEYDSLGGDFVFPRNQDFLNfEERSIRVGEfKRVEIMDGWVLKVVSVSN--GDYKSFLHIHHY
.|.| | || || .| ||||||. | .... | | .| . . |. | | . ... .. ..| | | ||
gqrryiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywpttesgtg.kygslsvtt.ktittkpdytitaliltnnttappstreishy
N--AWPHNNIPgnGSPKFVKQIWQLQSVLRKYSP--STPTVYMSLSGCGRAGTFALFETAHLSL-HSEQATLDLVKCLEMVRNGRIHACQNLTQFSFVYT
. .| . | || . . | .|| .| . | | .| | .. | | . .|| . .|. | | .. |.|
qftswkekttp..nvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiyq
|
|||||||||
| subfamily_CG42327_pd | Subfamily CG42327 | 391-455 | 2.6e-06 | 21.4 | In-house | 249-313 (319) | alignment | ||
Range on Protein: 391-455
Range on HMM: 249-313/319.0
PTVYMSLSGCGRAGTFALFETAHLSLHSEQATLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAE
| | | ||.|. . | || . ..|. . . ||..| .| .. |. |.| | |
PlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefiykvlse
|
|||||||||
| subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 295-458 | 4e-06 | 20.4 | In-house | 38-195 (440) | alignment | ||
Range on Protein: 295-458
Range on HMM: 38-195/440.0
DSEYDSLGGDFVFPRNQDFLNFEERSIRVGEFKRVEIMDgwVLkVVSVSNGDYKSFLHIHHYNAWPHNNIPGNGSPkFVKQIWQLQSVLRKYSpSTPTVY
|. || . | | .. | .. . . | | | | . | || |. .||..|| . .| .| .| | ... | . . | .
psdiaslpnnkvknryrnilaydhsrvmleevkgvpdsd..yi.nasyingiesrtlkqyhyqgwpdkgvpkfagp.vlkmiqdvnesqekag.ngpllv
MSLSGCGRAGTFALFETAhLSLHSEQATLDLVKCLEMVRNGRIHACQNLTQFSFVYTLLAEHIL
. .|.||.| .. | .|.. .. .|| | . | |..||. . | .|
hcsagagrtgviiavdsi.lreakrsdqidifsfinsmrnnrpqmvqtpeqyafvheavlegll
|
|||||||||