Gene F44E7.2 in Caenorhabditis elegans

Synonym: CELE_F44E7.2, F44E7.2

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HAD
Superfamily HAD
Family NagD
Subfamily PGP
Protein sequence
ID Type Fasta BLAST phosphatome Note
CeleP087_AA protein Get Run
CeleP087_AA_34-330 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_PGP_pd Subfamily PGP 48-332 5.5e-117 381.0 In-house 1-277 (279) alignment 
Range on Protein: 48-332
Range on HMM: 1-277/279.0
TFIFDADGVLWLGESVMPGSPRLIDYLVKHNKQIIVLTNNATKSRAVYAKKLAKLGYNssKMNKNNLVNPAAVVADTLHRAGLDGKrVYLIGEQGLRDEM
|..||.||||||||...||.......| |..|.....|||.||||. ..||..|||..  |.........||..||.|...  ..| ||..||.||..|.
tvlfDcDGVlWlgetaipgaaealnaLkklgKkvlfvtNnstksreellkkfkklgfe..kvkeeeilssaaaiadyLkqkkfekk.vyvlgeeglkeeL

DELGIEYFGHGPEKKQDEADgsGAFMYDIKLEENVGAVVVGYEKHFDYIKMMKASNYLREEGVLFVATNEDETCPGPNpEVVIPDAGPIVAAIKCASGRD
.| |||..|.||||..||.|  ..|....||...|||||||......|.|..||.|||||. |||.|||||...|... |||||.||..||||..||||.
keagiellgtgpeklkdeld..edfveelkldkdvgAVvvgvdeklsyakllkAanyLrepevlflatneDallplkk.evvipgaGslvaaieaasgrk

PLTVGKPCTPAFNYIKRKWNINPSRTMMIGDRTNTDVKFGRDHGMKTLLVLSGCHQIEDIIENQMNErdDMVPDYVAPCLGALVP
||..|||... ......|..|.|.||.|||||..||..||...|..|||||||....||. |....|  ..||||....|..|..
plvlGKPnelllelllekeeidpertlmiGDrlktDilfgkncGlqtLlvlsGvtkledveeikkee..klvPdyyldsladlle
Chronophin_1 48-330 4.4e-65 210.7 In-house 3-255 (261) alignment 
Range on Protein: 48-330
Range on HMM: 3-255/261.0
TFIFDADGVLWLGESVMPGSPRLIDYLVKHNKQIIVLTNNATKSRAVYAKKLAKLGYNSSKmnKNNLVNPAAVVADTLHRAGLdGKRVYLIGEQGLRDEM
....| ||||. ||...|| ..||  | ...|.....|||... |. .|..|..|| .. .  .....  |.  |  |... . . .||..||.|||.|.
lvLlDldGVlikgeeavpgAaeliealkqagkevlfvtNnsrrtreelaarlkrlGldava..aeeifssalaaaallrqqaa.kakvyvlGeeglrkel

DELGIEYFGHGPEkkqdeadgsgafmydikleeNVGAVVVGYEKHFDYIKMMKASNYLREEgVLFVATNEDETCPGPNPevVIPDAGPIVAAIKCASGRD
.| |.   ..  .                    .| ||||||...... |. .|....|.   ||||||.| | | ..   ..| .| ..||.. ||||.
reaGlrlvdeped....................rveaVvvGydeelsfeklaeaialirdg.alfvatnrDptvPleeG..iaPgtGslaaaveaAsgre

PLTVGKPCTPAFNYIKRKWNINPSRTMMIGDRTNTDVKFGRDHGMKTLLVLSGCHQIEDIIENQmnerDDMVPDYVAPCLGAL
|| |||| .  |. . .| ...|..|.|.||| .||...|.. |..|||||.|  . |.. . .    .|..||.|.  .  |
plvvGKPepvmfeealekigadpeetvmvGDRldTDilagaraglstllvltGvseleeaqayk....kdlrPdavvesiadl
Chronophin_2 48-328 9.9e-62 199.7 In-house 2-274 (282) alignment 
Range on Protein: 48-328
Range on HMM: 2-274/282.0
TFIFDADGVLWLGESVMPGSPRLIDYLVKHNKQIIVLTNNATKSRAVYAKKLAKLGYNSskMNKNNLVNPAAVVADTLHRAGLDGKRVYLIGEQGLRDEM
. .|| |||.| || ...|.| ... |... |... .|||.|..|  |..|.|.||.    ......   |   |  |  .     .|. || .||| |.
nvlfdcdgviwngekavagapevvsrlaragknvlfvtnnstrarenyvlkfarlgfad..vaaeqifssaycsaaylrdvadvrgkvfviggeglrkel

DELGIEYFGHGPEKKqdeadgsgAFMYDIKLEENVGAVVVGYEKHFDYIKMMKASNYLREEGVLFVATNEDETCPGPNPEvVIPDAGPIVAAIKCASGRD
 | |..  ..  |..        | .||. |. .| ||.|||.... ..|. ||. |||.   |..||..|   |  . . ..| .| . ||.. |||| 
reagvpvvedadeqe........asiydcaldpdvravlvgydekltflklakacaylrdadclllatdrdpwhplsdgr.itpgsgsltaaletasgrk

PLTVGKPCTPAFNYIKRKWNINPSRTMMIGDRTNTDVKFGRDHGMKTLLVLSGCHQIEDII---ENQMNERDDMVPDYVAPCLG
 . .|||    |. |  .....|.|..||||| .||. || . |..|.| |.|  ..|.     ..|. |. |.|||||  .. 
atvigkpsrfmfecissqfsvdparslmigdrletdilfgsncglstvltltgvssleeaqeysdsqlaeqrdlvpdyvvesia
Hydrolase_6 Haloacid dehalogenase-like hydrolase 49-153 1.2e-27 87.3 Pfam-A 1-101 (101) alignment 
Range on Protein: 49-153
Range on HMM: 1-101/101.0
FIFDADGVLWLGESVMPGSPRLIDYLVKHNKQIIVLTNNATKSRAVYAKKLAKLGYNsskMNKNNLVNPAAVVADTLHRAgLDGKRVYLIGEQGLRDEMD
|.|| ||||| |....||...... | ...|....||||..||.. ||||| |||..   ......| .| ..|. |..    .|.|..|||.|||.|..
flfDvdGvLwrgdkaipgaaealkalraagkpvvllTNnsskseeeyakkleklgvd...vteeqvvtsataaaeylkkr.kadkkvlvigeeglreelk

ELGIE
| |..
eaGfk
subfamily_LHPP_pd Subfamily LHPP 49-305 2.6e-27 87.2 In-house 1-224 (227) alignment 
Range on Protein: 49-305
Range on HMM: 1-224/227.0
FIFDADGVLWLGESVMPGSPRLIDYLVKHNKQIIVLTNNATKSRAVYAKKLAKLGYNsskMNKNNLVNPAAVVADTLHRAGLdgkRVYLIGEQGLRDEMD
.. |  |||. .....||.   .. | ...... ..||.  .|..  ...| .||..   ....... ........|..  |   | ||. |.. .....
vllDlsGvlhnedaaipgavealkrLrqagvkvrfvtNttkeskralverLirlgfd...veeeeiftsleaarqllrerkl...rpyllveddveedfe

ELGIEYFghgpekkqdeadgsgafmydikleenvGAVVVGY-EKHFDYIKMMKASNYLRE-EGVLFVATNEDETCPGPNPevVIPDAGPIVAAIKCASGR
..  .                              |||.|  ...|.| .. .| . | | ..   .| |..     ..   .. ..|. |.|.. | | 
didtdkp...........................navviglapesfeyetlnqafrllleakkakliainkgkyykrkdG..lalgpGafvkaleyatgv

DPLTVGKPCTPAFNYIKRKWNINPSRTMMIGDRTNTDVKFGRDHGMKTLLVLSGCHQIE
.   ||||    |.   .. ...|.. .|||| .. ||.   . |....|| .| .. |
kaevvGKPsalffekaleelgvdpeeavmiGDdvedDveGAlkaGlrgvlVktGkfrpe
Hydrolase haloacid dehalogenase-like hydrolase 46-290 2.9e-16 51.8 Pfam-A 1-214 (215) alignment 
Range on Protein: 46-290
Range on HMM: 1-214/215.0
IDTFIFDADGVLWLGESVM--PGSPRLIDYLVKH---------NKQIIVLTNNATKsravyakklaklgynsskmnKNnlVNPAAVVADTLHRAGLDGKr
|.|..|| .|.|. || ..  .|   ..... ..         .. ... ..| |.                    ..  .   |...     .  ||. 
iktvvfDktGTLtegepsvallgnkaalalaaaletgsehpigkavvaaakanstr....................gg..ltgfatfigrgvsgkvdgi.

vYLigeqGLRDEMDELGIEYFGHGPEKKQDEADGSGAFMYDIkleeNVGAVVVGYEKHFDYIKMMKASNYLREEGV-LFVAT-------NEDETCPGPNP
 .|    | .. | .||....     ...... |  .  . .    .. |. |  .    . ....| ..|.|.|. ....|       . . . .| . 
.vl....gnpewmtalglrviapdlvaaegqskgrtvvvvav....qaralgviafadpvkpeaaeavasLkeaGievvlltgdnpetaeaiakqagied

EVVIPDAGpivaaikcasgrdpltvGKPCTPAFNYIKRKWNINPSRTMMIGDRTnTDVKFGRDH
..|  ..                  |||    |... ....|.|....|.||.  .|.....  
slvfaevv.................gkPepklfvaaieeLqidpgevamvGDgv.nDapalaaA
Hydrolase_like HAD-hyrolase-like 252-323 2.8e-14 44.1 Pfam-A 3-68 (75) alignment 
Range on Protein: 252-323
Range on HMM: 3-68/75.0
GKPCTPAFNYIKRKWNINPSRTMMIGDRTNTDVKFGRDHGMKTLLVLSGCHQIEDIIEnqmnerDDMVPDYV
|||    . .. .. ...||...||||. .||.....  |....|||.| .. ||  .      .   ||||
gKPnpgmydkalevlgappsevvmiGDslatDieaAnnaGirsilVltGvsreedlkl......akakpdyv
HAD_2 Haloacid dehalogenase-like hydrolase 247-297 2.1e-06 19.4 Pfam-A 127-176 (176) alignment 
Range on Protein: 247-297
Range on HMM: 127-176/176.0
DPLTVGKPCTPAFNYIKRKWNINPSRTMMIGDRTnTDVKFGRDHGMKTLLV
|   . ||.  |. .. .. ...| ....|.|.   ||. .|. |..| .|
ddvgapKpdpeayekvlerlgvkpeeilfidDsl.edveaAraaGirtvhv
CECR5_TIGR01456 35-96 3.7e-06 16.6 In-house 28-92 (370) alignment 
Range on Protein: 35-96
Range on HMM: 28-92/370.0
CPDTFAKVMKTIdTFIFDADGVLWLGESVMPGSPRLIDYLVKHNKQ----IIVLTNNATKSRAVYA
   ....  |.. .|..| |||| .|.....|..  .  ||... .    ...|||    |    |
skvspessskkf.gfaldiDGvllrGkkpiagaskalrrLvddqGalkiPvllltngGglserara