Gene K02D10.1 in Caenorhabditis elegans

Synonym: CELE_C53A3.2, C53A3.2

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HAD
Superfamily HAD
Family NagD
Subfamily PGP
Protein sequence
ID Type Fasta BLAST phosphatome Note
CeleP115_AA protein Get Run
CeleP115_AA_15-261 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_PGP_pd Subfamily PGP 17-263 3.5e-94 306.2 In-house 1-241 (279) alignment
Range on Protein: 17-263
Range on HMM: 1-241/279.0
TFLFDADGVLWTGDIPVPGAIEWINLLLeDPSKKVFVLTNNSTKTLEQYMKKIEKLGFGHLGRNNVISPAIVLADYLKSnaDKFSGEyVYLIGTENLKAT
|.|||.|||||.|. ..|||.|..| |  .  |||...||||||. |...||..|||| .. .....|.|...|||||.  .||... ||..|.|.||..
tvlfDcDGVlWlgetaipgaaealnaLk.klgKkvlfvtNnstksreellkkfkklgfekvkeeeilssaaaiadyLkq..kkfekk.vyvlgeeglkee

LENDgGVKCFGTGPDSIRDHTDGDFIHKVDMSIAPKAVVCSYDAHFSYPKIMKASNYLQDPSVEYLVTNQDYTFPGPVpGVVIPGSGATSAAVTAVTGRD
|..  |....||||....|..|.||....... . .|||...| ..||.|..||.|||..|.|..|.||.| ..|..  .|||||.|.. ||..|..||.
Lkea.giellgtgpeklkdeldedfveelkldkdvgAVvvgvdeklsyakllkAanyLrepevlflatneDallplkk.evvipgaGslvaaieaasgrk

PKVFGKPHKPMADFLLRRAHVDPKRTVMFGDRLDTDIMFGNANGQLS
| |.|||.......||.. ..||.||.|.||||.|||.||...|  .
plvlGKPnelllelllekeeidpertlmiGDrlktDilfgkncGlqt

Chronophin_1 16-261 5.1e-56 181.0 In-house 2-221 (261) alignment
Range on Protein: 16-261
Range on HMM: 2-221/261.0
DTFLFDADGVLWTGDIPVPGAIEWINLlLEDPSKKVFVLTNNSTKTLEQYMKKIEKLGFGHLGRNNVISPAIVLADYLKSnadKFSGEYVYLIGTENLKA
...|.| ||||. |.  |||| | |.  |..  |.|...||||..| |.. .....||. ..  ....| |.  | .|..   . ..  ||..|.| |..
qlvLlDldGVlikgeeavpgAaeliea.lkqagkevlfvtNnsrrtreelaarlkrlGldavaaeeifssalaaaallrq...qaakakvyvlGeeglrk

TLENDGGVKCFGTGPdsirdhtdgdfihkvdmsiAPKAVVCSYDAHFSYPKIMKASNYLQDPsVEYLVTNQDYTFPGPVpGvVIPGSGATSAAVTAVTGR
 |...| .   .. .                   ...|||  || ..|. |. .|.....|.   ...||.| |.| .  | ..||.|.  |||.| .||
elreaGlrlvdeped...................rveaVvvGydeelsfeklaeaialirdg.alfvatnrDptvPlee.G.iaPgtGslaaaveaAsgr

DPKVFGKPHKPMADFLLRRAHVDPKRTVMFGDRLDTDIMFGNANGQ
.| | |||.  | .  |..  .||..||| |||||||| .|.  | 
eplvvGKPepvmfeealekigadpeetvmvGDRldTDilagaragl

Chronophin_2 17-260 4.9e-49 158.1 In-house 2-234 (282) alignment
Range on Protein: 17-260
Range on HMM: 2-234/282.0
TFLFDADGVLWTGDIPVPGAIEWINLLLEdPSKKVFVLTNNSTKTLEQYMKKIEKLGFGHLGRNNVISPAIVLADYLKSNAdKFSGEyVYLIGTENLKAT
. ||| |||.| |.  |.|| | ...| .   |.|. .|||||.. |.|..|. .|||  .  ....| |.  | ||.  | . .|. |. ||.| |.. 
nvlfdcdgviwngekavagapevvsrlar.agknvlfvtnnstrarenyvlkfarlgfadvaaeqifssaycsaaylrdva.dvrgk.vfviggeglrke

LEnDGGVKCFGTGPDSIrdhtdgDFIHKVDMSIAPKAVVCSYDAHFSYPKIMKASNYLQDPSVEYLVTNQDYTFPGpVPGVVIPGSGATSAAVTAVTGRD
|. . ||.. .   ..         |... ..   .||.  || .... |. ||. ||.|.   .| |..|   |    | ..||||. .||. . .|| 
lr.eagvpvvedadeqe......asiydcaldpdvravlvgydekltflklakacaylrdadclllatdrdpwhpl.sdgritpgsgsltaaletasgrk

PKVFGKPHKPMADFLLRRAHVDPKRTVMFGDRLDTDIMFGNANG
  | ||| . | . .     ||| |..| ||||.|||.||.  |
atvigkpsrfmfecissqfsvdparslmigdrletdilfgsncg

NIPSNAP NIPSNAP 427-524 1e-33 101.9 Pfam-A 1-102 (102) alignment
Range on Protein: 427-524
Range on HMM: 1-102/102.0
YDLRSYVLQPGTMIDWASAWAKGIQYRRE--ANQDVGGFFAQVGQLYVVYHIWAYPSMSGRNDTRHATWAKPGWDATVANTVPL--IKKMQSKILTPTKY
| ||.| |.||.. ....|.|. .... |   .. .| |....|.|..|.|.||..|.  |...|.| .|.|.|.|.|...|.|  |..|.|.|||||..
yelrtYrlkpgklaefleafarawielqerhggeliGyfaseiGalnqvvhlwafdslaareayraalaadpeweaaveravdldliesmesriltptpf

SQ
|.
sp

Hydrolase_6 Haloacid dehalogenase-like hydrolase 18-121 7e-27 84.8 Pfam-A 1-99 (101) alignment
Range on Protein: 18-121
Range on HMM: 1-99/101.0
FLFDADGVLWTGDIPVPGAIEWINLLLEDpSKKVFVLTNNSTKTLEQYMKKIEKLGFGhLGRNNVISPAIVLADYLKSNADkfsGEYVYLIGTENLKATL
|||| ||||| || ..||| | .. | .   |.|..|||||.|. |.|.||.||||.  .  ..|...| ..|.|||..     .. |..||.|.|.. |
flfDvdGvLwrgdkaipgaaealkalraa.gkpvvllTNnsskseeeyakkleklgvd.vteeqvvtsataaaeylkkrka...dkkvlvigeeglreel

ENDG
.. |
keaG

subfamily_LHPP_pd Subfamily LHPP 18-254 2.5e-19 61.1 In-house 1-204 (227) alignment
Range on Protein: 18-254
Range on HMM: 1-204/227.0
FLFDADGVLWTGDIPVPGAIEWINLLlEDPSKKVFVLTNNSTKTLEQYMKKIEKLGFGhLGRNNVISPAIVLADYLKSNADkfsgeyvyligtenlkatl
.| |  |||...| ..|||.| .. |  . ..|| ..||.. .. .. .... .|||. .  ....... . ...|...                     
vllDlsGvlhnedaaipgavealkrL.rqagvkvrfvtNttkeskralverLirlgfd.veeeeiftsleaarqllrerkl...................

endggvK--------------------CfgtgpdsirdhtdgdfihkvdmsiapKAV-VCSYDAHFSYPKIMKASNYLQDPSVEYLVTNQDYTFPGPVPG
      .                                               .|| . . ...|.| .. .| . | . . . |.. .   .     |
......rpyllveddveedfedidtdkp..........................navviglapesfeyetlnqafrllleakkakliainkgkyykrkdG

VVIpGSGATSAAVTAVTGRDPKVFGKPHKPMADFLLRRAHVDPKRTVMFGDRLDTDIM
... | ||  .|.   || . .| |||.. . .  |.. .|||.. || || .  |. 
lal.gpGafvkaleyatgvkaevvGKPsalffekaleelgvdpeeavmiGDdvedDve

Hydrolase haloacid dehalogenase-like hydrolase 15-258 1.4e-14 46.3 Pfam-A 1-213 (215) alignment
Range on Protein: 15-258
Range on HMM: 1-213/215.0
YDTFLFDADGVLWTGDIPV--PGAIEWINLLLED--------PSKKVFVLTNNSTKtlEQYMKKIEKLGFGHLGRNNVIspaivladYLkSNADKFSGEY
..|..|| .|.|..|  .|  .|. ....|. .          .. |.. ..|||.  .  .   .  | |  |. ..|        .| .| .   .  
iktvvfDktGTLtegepsvallgnkaalalaaaletgsehpigkavvaaakanstr..ggltgfatfigrgvsgkvdgi........vl.gnpewmtalg

VYLIGTENLKATL-ENDGGVKCFGTgpdsirdhtdgdfihkvdmsiapkAVVCSYDAHFS---YPKIMKASNYLQDPSV-EYLVT-------NQDYTFPG
.  |  ....|   . .. |  ...                        ...  .. .|.   .|....| ..|..  .  .|.|       . . ...|
lrviapdlvaaegqskgrtvvvvav........................qaralgviafadpvkpeaaeavasLkeaGievvlltgdnpetaeaiakqag

PvpgvvipgsgaT-SAAV---TavtgrdpkvfGKPHKPMADFLLRRAHVDPKRTVMFGDRLdTDIMFGNA
            . |. .   .          |||.. .   ....  .||....|.||.. .|. .. |
i...........edslvfaevv..........gkPepklfvaaieeLqidpgevamvGDgv.nDapalaa

Hydrolase_like HAD-hyrolase-like 220-260 3.4e-11 34.3 Pfam-A 2-42 (75) alignment
Range on Protein: 220-260
Range on HMM: 2-42/75.0
FGKPHKPMADFLLRRAHVDPKRTVMFGDRLDTDIMFGNANG
 |||.. | |. |......|...|| ||.|.||| ..|. |
lgKPnpgmydkalevlgappsevvmiGDslatDieaAnnaG

NIPSNAP NIPSNAP 314-369 6.3e-08 19.1 Pfam-A 1-54 (102) alignment
Range on Protein: 314-369
Range on HMM: 1-54/102.0
YEFMTHNYRPGEQDAYLDAFGKYKNEMnQKNPSIELVGSWTCAYGRtRDQAIHLWR
||..|.  .||.  ..| || .. .|  |.   .||.| ..  .|.  .|..|||.
yelrtYrlkpgklaefleafarawiel.qerhggeliGyfaseiGa.lnqvvhlwa