Gene K07F5.6 in Caenorhabditis elegans

Synonym: CELE_K07F5.6, K07F5.6

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family PTP
Subfamily CelePTP-sf17
Protein sequence
ID Type Fasta BLAST phosphatome Note
CeleP117_AA protein Get Run
CeleP117_AA_97-437 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_Cele-PTP-17_pd Subfamily Cele-PTP-17 99-445 1.5e-232 765.2 In-house 1-347 (347) alignment
Range on Protein: 99-445
Range on HMM: 1-347/347.0
FCKYLLDIKEASLSTYFDEHLAGYTPPNFTSVEWEKSLSKNRSKNHKLNDNTRVILSPENTENSRTDPPDTYINASHIKFDNSQKEFIVTQYPLPDTVRD
|||||||||||||||||||.||.|.|..||||||||||||||||..||.|.|||.||||...|||.|...||||||||||||..||.|.|||||||||||
fckylldikeaslstyfdenlanyspskftsvewekslsknrskdvklidatrvvlspeksknsraddvetyinashikfdnaskeyiltqyplpdtvrd

FWRMVSIMKVTQIVTIFEPQTDEAIEEFRNPTLTLAAPAPTSTMTTIGGFPVPIGQIAHNRDQIQGQSIRCESNVHRSSFFPLETDHYMNLKGWLINTRR
||.|||..||||.||||||..|||||||.|.||.|.|||||.....||..||||.|||..|.||...|||||||.|||||||||||||.||||||||||.
fwkmvsvtkvtqvvtifepikdeaieefanatlslvapaptasskdigsspvpidqiarereqieiksircesnlhrssffpletdhylnlkgwlintra

VTVDHRNKGWMNKYTVEVVAEGCSEATFAKVYNCTTWPWKKYPDDEKKVLALVRAPYKDTSTSLIANLEKLAPIVVMCDLGLDRSATVVLTSIIIDQIIA
|.||.|||.|||||||||||||||||||||||||||||||||||||||||||||||.|..|||||||||||||.|||||||||||||||||||||.|...
vevdqrnknwmnkytvevvaegcseatfakvyncttwpwkkypddekkvlalvrapvkesstslianleklapvvvmcdlgldrsatvvltsiiieqvld

GKTPDCDALFKKMRDQRAGVFTMSIFYTYAIRAALFYMKIKLQTMND
|||||||.|||||||||||||||||||||||||||||.|.||||.|.
gktpdcddlfkkmrdqragvftmsifytyairaalfylklklqtlne

DSPc_SM00195 111-437 4.1e-78 257.7 In-house 2-263 (263) alignment
Range on Protein: 111-437
Range on HMM: 2-263/263.0
LSTYFDEHLAGYTPPNFTSVEWEKSLSKNRSKNHKLNDNTRVILSPENTEnsrtdPPDTYINASHIKFDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQ
|...|..... ..| ..|..|..|. ||||.||....|.|||.|..|...     ....||||..||..|..|..|.||.|||.||.||||||. .||..
lkeefekleestspketteaekkknksknRyknilpydhtrVklkkeekk.....egsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvki

IVTIFEPQTDeaieefrnptltlaapaptstmttiggfpvpigqiahnrdqiqgQSIRCESNVHRSSfFPLETDHYMNLKGWLINTRRvtvdhrnkGWMN
||...|....                                            ....|.......|    || .....| .  ....         ...
ivmlteeeen............................................gkekcdrywpees.ggketfgkisvklvevekkk........deii

KYTVEVVAEGCSEATFAKVYNCTTWPWKKYPDDEKKVLALVRAPYKDTSTSlianlekLAPIVVMCDLGLDRSATVVLTSIIIDQIIAGKTPDCDALFKK
..|.|. .||..|......|....||....||..|.||.|.|| .|..|||        .||||.|. |..|..|.|...||.... ..|..|.....|.
lrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkksksts.......sgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivke

MRDQRAGVFTMSIFYTYAIRAALFYMK
.|.||.|..... .|.....|.|.|.|
lRkqRpgmvqtleqYlfiyeaileyik

PTPc_SM00194 111-437 4.1e-78 257.7 In-house 2-263 (263) alignment
Range on Protein: 111-437
Range on HMM: 2-263/263.0
LSTYFDEHLAGYTPPNFTSVEWEKSLSKNRSKNHKLNDNTRVILSPENTEnsrtdPPDTYINASHIKFDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQ
|...|..... ..| ..|..|..|. ||||.||....|.|||.|..|...     ....||||..||..|..|..|.||.|||.||.||||||. .||..
lkeefekleestspketteaekkknksknRyknilpydhtrVklkkeekk.....egsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvki

IVTIFEPQTDeaieefrnptltlaapaptstmttiggfpvpigqiahnrdqiqgQSIRCESNVHRSSfFPLETDHYMNLKGWLINTRRvtvdhrnkGWMN
||...|....                                            ....|.......|    || .....| .  ....         ...
ivmlteeeen............................................gkekcdrywpees.ggketfgkisvklvevekkk........deii

KYTVEVVAEGCSEATFAKVYNCTTWPWKKYPDDEKKVLALVRAPYKDTSTSlianlekLAPIVVMCDLGLDRSATVVLTSIIIDQIIAGKTPDCDALFKK
..|.|. .||..|......|....||....||..|.||.|.|| .|..|||        .||||.|. |..|..|.|...||.... ..|..|.....|.
lrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkksksts.......sgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivke

MRDQRAGVFTMSIFYTYAIRAALFYMK
.|.||.|..... .|.....|.|.|.|
lRkqRpgmvqtleqYlfiyeaileyik

0036941 (Phosphotyrosine protein) phosphatases II 107-444 1.3e-58 194.1 In-house 11-285 (297) alignment
Range on Protein: 107-444
Range on HMM: 11-285/297.0
KEASLSTYFDEHLAGYTPPNFTSVEWEKSLSKNRSKNHKLNDNTRVILspentensrTDPPDTYINASHIKFDNSQKEFIVTQYPLPDTVRDFWRMVSIM
  | |...|.| |  . .....  .... |.|||.|.   .|.|||.|         .|... |||||.... . ...||.||.|||.|| ||||||   
flalllkefeellpllllgslsvallpenleknRykdilpydhtRVkl.........ddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweq

KVTQIVTIFEPQTDEAIEefrnptltlaapaptstmttiggfpvpigqiahnrdqiqgqsircesnvhRSSFFPLETDHYMNLKGWLINTRRVTVDhrNK
.|| ||.. |.  .. .                                                     ...|||...... ... .....|.|.  ..
nvtvIvmltelvelgrek..................................................caqywpleegesltygdftvtllsvevv..ll

GWMNKYTVEVVAEGCSEATFAKVYNCTTWPWKKYPDDEKKVLALVRAPYKDTSTSlianlEKLAPIVVMCDLGLDRSATVVLTSIIIDQII---AGKTPD
...  .|.||.  |..|  . ... .|.||. . |.. . .|.....  |  . .      .  |..|.|  |. ||.|...  ....|.      ...|
ddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrkvlkll.....psggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvd

CDALFKKMRDQRAGVFTMSIFYTYAIRAALFYMKIKLQTMN
   ..||.|.||.|....  .| . ..| |.. | ||. ..
ileavkklReqRpgavqtleqyrflyeallellkkkltkep

0040438 (Phosphotyrosine protein) phosphatases II 98-442 4.5e-55 182.5 In-house 4-282 (317) alignment
Range on Protein: 98-442
Range on HMM: 4-282/317.0
GFCKYLLDIKEASLsTYFD---EHLAGYTPPNFTSVEWEKSLSKNRSKNHKLNDNTRVILSPENTensrtDPPDTYINASHIKFDNSQKEFIVTQYPLPD
.....|||..  .  |..    |.|  .......  |.... .|||...  ..|..||.|||..      |....|||||.... | ...||.||.|||.
dlllalldllksdf.talleefedllslkldtysvaelpenkdknrypdilpydhsRVkLsplgg.....dldsdYInAsyvdgpnlkrkfIatqgPlpn

TVRDFWRMVSIMKVTQIVTIFEPQTDEAIEefrnptltlaapaptstmttiggfpvpigqiahnrdqiqgqsircesnvhRSSFFPLetDHYMNLKGWLI
|| ||||||   .|| ||.. |.  .. .                                                      ..||  ..... ... .
tvedFwrmvweqgvtvivmLteleelgrek..................................................caqYwpl..getltygdftv

NTRRVTVdhrnKGWMNKYTVEVVAEGCSEATFAKVYNCTTWPWKKYPDDEKKVLALVRAPYKDTStslianlEKLAPIVVMCDLGLDRSATVVLTSIIID
... ...    .. .. .|.||.  |.||  . ... .|.||  . |.. . .|....|  .  .       ..  |..|.|  |..|..|...  ....
tllseee....lagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavreale.......dpggpvlVHCsaGvgRtGtfiaaylmle

QIIAGKTPDCDALFKKMRDQRAGVFTMSIFYTYAIRAALFYMKIKLQT
|.  ....| .  .|..| ||.|....  .| . ..|.|.|.| ||. 
qlekeggvdveeavkelreqRpgavqtpeqyrflydalleylkrkltl

0050432 (Phosphotyrosine protein) phosphatases II 110-443 1.1e-54 181.3 In-house 43-306 (308) alignment
Range on Protein: 110-443
Range on HMM: 43-306/308.0
SLSTYFDEHLAGYTPPNFTSVEWEKSLSKNRSKNHKLNDNTRVILspentensrtDPPDTYINASHIKFD--NSQKEFIVTQYPLPDTVRDFWRMVSIMK
 |...| | |. ........ ....  .|||.|.   .|..||.|          |....|||||....   .....||.||.|||.|| ||||||   .
lleeefeellsvkplleysvallpenkdkNrykdilpydhsRVkl..........degsdYInAsyvdgyssklprkfIatqgPlpntvedFwrmvweqn

VTQIVTIFEPQTDEAIEefrnptltlaapaptstmttiggfpvpigqiahnrdqiqgqsircesnvhRSSFFPLETD-HYMNLKGWLINTRRVTVdhrnK
|. ||.. ... .. .                                                      ..|||.. .... ... .......|    .
vrvIvmLtklvengrek..................................................caqYwplelgggsleygkftvtllseev....l

GWMNKYTVEVVAEGCSEATFAKVYNCTTWPWKKYPDDEKKVLALVRAPYKDTSTslianleklAPIVVMCDLGLDRSATVVLTSIIIDQIIAGKTPDCDA
... ..|.|..  |..|  . ... .|.||  . |.. . .|.....  |  .           ||||.|  |. |..|...  ....|. .....|   
ddytvrtleltnlgdgesrtvthfhytnWpdhgvPpspeilldflelvrkslpg.........gpivVHCsaGvGRtGtfialdllleqlekeggvdvfe

LFKKMRDQRAGVFTMSIFYTYAIRAALFYMKIKLQTM
..||.| ||.|...    | . .||.|.|.| ||. .
avkklReqRpgmvqtpeqylflyralleylklkltkl

0047943 (Phosphotyrosine protein) phosphatases II 113-436 5.3e-53 175.6 In-house 16-272 (273) alignment
Range on Protein: 113-436
Range on HMM: 16-272/273.0
TYFDEHLAGYTPPNFTSVEWEKSLSKNRSKNHKLNDNTRVILspentensrTDPPDTYINASHIKFDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIV
  |.. |  ... ...  .... ..|||.|.   .|..||.|         .|... |||||.... |....||.||.|||.|| ||||||   .|. ||
eefelllslkplltysvallpenkdknrykdilpydhsrvkl.........gdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvweqnvrviV

TIFEPQTDEAIEefrnptltlaapaptstmttiggfpvpigqiahnrdqiqgqsircesnvhRSSFFPLETDH-YMNLKGWLINTRRVTVdhrnKGWMNK
.. |.. .. .                                                      ..||| .. ... . . ........    |... .
mLtelvelgrek..................................................caqYwpleggelsltygkftvtllseet....kddytv

YTVEVVAEGCSEATFAKVYNCTTWPWKKYPDDEKKVLALVRAPYKD------TstslianleklAPIVVMCDLGLDRSATVVLTSIIIDQIIAGKTPDCD
.|.|..  |..|  . ... .|.||  . |.. . .| ....  |                    |.||.|  |. |..|...  ...||.......| .
rtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvrkalealpsn...........gpvvVHCsaGvgRtgtfialdllldqlekeggvdvl

ALFKKMRDQRAGVFTMSIFYTYAIRAALFYM
 ..|..|.|| |...   .| . ..|.|.|.
eavkllrsqRpgmvqtpeqyrflyealleyl

0051299 (Phosphotyrosine protein) phosphatases II 110-436 2.5e-51 170.2 In-house 24-286 (288) alignment
Range on Protein: 110-436
Range on HMM: 24-286/288.0
SLSTYFDEHLAGYTPPNFTSVEWEKSLSKNRSKNHKLNDNTRVILSPENTensrtDPPDTYINASHIKFDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVT
 |   |.| |. ........  ... |.|||...   .|..||.||...      .....|||||.|.. |....||.||.|||.|| ||||||   .|.
glleefeellsllpdltlsaallpenleknRysdilpydhsRVkLsvldg.....vegsdYinAsyidgynlkrkfIatqgPlpntvedFWrmvweqnvr

QIVTIFEPQTDEAIEefrnptltlaapaptstmttiggfpvpigqiahnrdqiqgqsircesnvhRSSFFPLetDHYMNLKGWLINTRRVTVdhrnKGWM
 ||.. ... .. .                                                      ..||  ....... . .......|    .. .
vIvmltklvelgrek..................................................caqYwpl..ggsltygditvtllseev....lddy

NKYTVEVVAE----GCSEATFAKVYNCTTWPWKKYPDDEKKVLALVRAPYKDTStslianlEKLAPIVVMCDLGLDRSATVVLTSIIIDQIIAGKTPDCD
 ..|.||.      |..|  . ... .|.||   .||. . .|...|. .|  .        .  |.||.|  |..|..|...  ....|. .....|  
tvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdspellldflrlvrkala.......sgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvl

ALFKKMRDQRAGVFTMSIFYTYAIRAALFYM
 ..|..| || |....   | . ..|.|.|.
eavkrlreqRpgmvqtpeqyrfvyealleyl

0043336 (Phosphotyrosine protein) phosphatases II 117-436 1.1e-49 164.7 In-house 27-277 (278) alignment
Range on Protein: 117-436
Range on HMM: 27-277/278.0
EHLAGYTPPNFTSVEWEKSLSKNRSKNHKLNDNTRVILSPENTensrtDPPDTYINASHIKFDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVTIFE
|.|  .......  ..... .|||.|.  ..|..||.||...      |....|||||.... | ...||.||.|||.|| ||||||   .|| ||.. |
eellsfkldtysiallpenkdknrykdilpydhsrvklsllgg.....dldsdYinAsyvdgynvprkfiatqgPlpetvedFwrmvwelgvttivmLte

PQTDEAIEefrnptltlaapaptstmttiggfpvpigqiahnrdqiqgqsircesnvhRSSFFPletDHYMNLKGWLINTRRVTVdhrnKGWMNKYTVEV
.  .. .                                                      ..|   ..... ... ........    ....  .| ||
lvelgrvk..................................................caqYwp...ggsltygdftvtllkeeh....lddytvrtlev

VAEGCSEATFAKVYNCTTWPWKKYPDDEKKVLALVRAPYKDTStslianlEKLAPIVVMCDLGLDRSATVVLTSIIIDQIIAGKTPDCDALFKKMRDQRA
.  |..|  .  .| .. ||  . |.. . .| ...|  .  .        .  |..|.|  |..|..|...  ....|.  ....| .  .|..| ||.
tnlgdgesrtvthyhylgwpdhgvpeslsllldflkavreale.......dsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRp

GVFTMSIFYTYAIRAALFYM
| ...  .| . ..|.|.|.
gavqtpsqyrflyealleyl

0046845 (Phosphotyrosine protein) phosphatases II 126-443 1.5e-49 164.3 In-house 19-281 (284) alignment
Range on Protein: 126-443
Range on HMM: 19-281/284.0
NFTSVEWEKSLSKNRSKNHKLNDNTRVILSPENTENSRTDppdtYINASHIKFD-----NSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVTIFEPQTD
...   ... |||||.|.   .|..||.|.... . . .|    |||||....      ...|.||.||.|||.|| ||||||   .|. ||.. |.  .
slsvallpenlsknRykdilpydhsRVklksldgdledsd....YinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqnvrvIVmltelven

EAIEefrnptltlaapaptstmttiggfpvpigqiahnrdqiqgqsircesnvhRSSFFPLEtDHYMNLKGWLINTRRVTVdhrnKGWMNKYTVEVVAEG
. .                                                    . ..||| ......... .......|    |... ..|.|.. .|
grek..................................................caqYwple.gevltygdftvtllseev....kddytvrtleltnlg

-CSEATFAKVYNCTTWPWKKYPDDEKKVLALVRAPYKDTSTslianLEKLAPIVVMCDLGLDRSATVVLTSIIIDQIIAGK---TPDCDALFKKMRDQRA
 ..|  . ... .|.||  . |.. . .|...|.  .  .      |..  ||||.|  |. |..|...  ....|.....   ..|   ..|..|.|| 
ytgesrtvthfhytswpdhgvppspedlleflrlvrellen.....lpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRp

GVFTMSIFYTYAIRAALFYMKIKLQTM
| ...   | . ..|.|.|.| ||. .
gmvqtleqyrfvyealleylklkltll

0039614 (Phosphotyrosine protein) phosphatases II 116-440 3.7e-49 163.1 In-house 38-293 (297) alignment
Range on Protein: 116-440
Range on HMM: 38-293/297.0
DEHLAGYTPPnFTSVEWEKSLSKNRSKNHKLNDNTRVILSPENtensRTDPPDTYINASHIKFDNS-QKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVTI
 |.|  ..|. ..  ..... .|||.|..  .|..||.|.||.     .|....|||||.... .  ...||.||.|||.|| ||||||   .|| ||..
feellslkpd.ysiallpenkdknrykdilpydhsrvklkped....gvdldsdYinAsyvdgydlltrkfIatqgPlpetvedFwrmvweqgvtvivmL

FEPQTDEaieefrnptltlaapaptstmttiggfpvpigqiahnrdqiqgqsircesNvHRSSFFPLETDhymNLKGWLINTRRVTVdhrnKGWMNKYTV
 ..  ..                                                  . .  ...| |..   . ... .....|..    .. .. .| 
tklvelg..................................................r.kcaqywpeegg...tygdftvtllkveh....ldgytvrtl

EVVAEGCSeaTFAKVYNCTTWPWKKYPDDEKKVLALVRAPYKDTSTSlianlEKLAPIVVMCDLGLDRSATVVLTSIIIDQIIAGKTPDCDALFKKMRDQ
||. .|.|   . ... .| ||. . |.. . .| ....  .  ...     .|  |..|.|  |..|..|...  ....|.  ....| .  .|..| |
evtnnges..rtvthfqytgwpdhgvppslellleflelvrealael.....pkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreq

RAGVFTMSIFYTYAIRAALFYMKIKL
| |....  .| . ..|.|.. | ||
Rpgavqtpsqyrflydallellkrkl

0045450 (Phosphotyrosine protein) phosphatases II 124-436 8.4e-49 162.3 In-house 44-304 (307) alignment
Range on Protein: 124-436
Range on HMM: 44-304/307.0
PPNFTSVEWEKSLSKNRSKNHKLNDNTRVILSPENTEnsrtDPPDTYINASHI--------KFDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVTIF
. .... ..... .|||.|.  ..|.|||.||... .    .... |||||..        .. .....||.||.|||.|| |||||.   .|| ||.. 
lgeysiallpenkdknrykdilpydhtRVklssldgs....ledsdYiNAsyvrvpllllldgydlkrkfIatqgPlpetvedFwrmlweqgvtvivmlt

EPQTdeaieefrnptltlaapaptstmttiggfpvpigqiahnrdqiqgqsircESNVHRSSFFPLEtDHYMNLKGWLINTRRVTVdhrnKGWMNKYTVE
|.                                                      ..    ..|.| ..... . . ........    .. .  .|.|
elve..................................................lgrekcaqywPde.geeltygnftvtllseeh....ldgytvrtle

VVAE-GCSEATFAKVYNCTTWPWKKYPDDEKKVLALVRAPYKdtstsLIANLEKLAPIVVMCDLGLDRSATVVLTSIIIDQIIAGKT---PDCDALFKKM
|    |..|  . ... .|.||  . |.. . .|.....  |      ...| |  |..|.|  |..|..|...  ....|. ...|   .| .  .|..
vtdldgtgesrtvthfhytgwpdhgvppsfeelldfieevrk.....aleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkll

RDQRAGVFTMSIFYTYAIRAALFYM
|.|| |...   .| . ..|.|.. 
reqRpgavqnpeqyrflyeallell

0040439 (Phosphotyrosine protein) phosphatases II 126-436 1.3e-44 148.0 In-house 2-246 (249) alignment
Range on Protein: 126-436
Range on HMM: 2-246/249.0
NFTSVEWEKSLSKNRSKNHKLNDNTRVILSPENTensrtDPPDTYINASHIKFDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVTIFEPQTDEAIEe
...  .......|||....  .|..||.||. .       ... |||||.|.. .....||.||.|||.|| |||||.   ..| ||.. ...  . .  
eysvallpenkdknrypdilpydhsrvklsilpg.....lflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrek.

frnptltlaapaptstmttiggfpvpigqiahnrdqiqgqsircesnvhRSSFFPLetDHYMNLKGWLINTRRVTVdhrnKGWMNKYTVEVVAEGCSEAT
                                                    ..||  ..... ... .....|.|    |...  .|.|..  ...|  
.................................................caqywpl..ggsleygdftvtllsvev....kddytvrtleltnlydgesr

FAKVYNCTTWPWKKYPDDEKKVLALVRAPYKDTSTSlianlEKLAPIVVMCDLGLDRSATVVLTSIIIDQIIAGKTPDCDALFKKMRDQRAGVFTMSIFY
  .....| ||  . |.. . .|....|  |  ..      .|  |..|.|  |..|..|...  ....|.   .. | .  .|..|.|| |....  .|
tvlhiqytdwpdhgvppsfedlldfieavrkaleel.....pkggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdleeavkllrsqRpgavqnpeqy

TYAIRAALFYM
 . ..|.|.. 
rflyeallell

0045098 (Phosphotyrosine protein) phosphatases II 110-438 2.1e-43 144.1 In-house 8-274 (278) alignment
Range on Protein: 110-438
Range on HMM: 8-274/278.0
SLSTYFDEHLAGYTPPNFTSVEWEKSLSKNRSKNHKLNDNTRVIlspentensrtdppDtYINASHIKFDnsQKEFIVTQYPLPDTVRDFWRMVSIMKVT
.|...|.. |. . |  .|   ....|.||| |.   .|..||.              | |||||.|..   .|.||.||.|||.|| |||||.  ...|
dlllefefllllgipseitpalylgnldknRykdilpydhsrVk..............d.YINAsyidgy..pkkfIatqgPlpstvadfwrmlwelgit

QIVTIFEPQTDEaieefrnptltlaapaptstmttiggfpvpigqiahnrdqiqgqsircesNVHRSSFFPlEtDHYMNLKGWLINTRRVTVDhrNKGWM
 ||.. | . ..                                                  ...   ..| | ..... ... ...  ..|   .. ..
vivmltelvelg..................................................rekcaqywp.e.ggsltygdftvtllseevl..ddytl

NKYTVEVV--AEGCSEATFAKVYNCTTWPWKKYPDDE--KKVLALVR-------APYKDTSTSLIANLEKlAPIVVMCDLGLDRSATVVLTSIIIDQIia
 ...|. .   .   |  . .......||    |...  | .| |..       . .. ...||... ..  |..| |  |..|..|.|.  ......  
rtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsg.gpvlVHCsaGvgRtGtlvaaylmlell..

GKTPDCDALFKKMRDQRAG-VFTMSIFYTYAIRAALFYMKI
... | .  .|..| || | ....  .| . ....| . . 
eggvdlleavkelrsqRpglavqnleqyrflyefllelllr

0042113 (Phosphotyrosine protein) phosphatases II 128-436 2.8e-43 143.5 In-house 2-243 (245) alignment
Range on Protein: 128-436
Range on HMM: 2-243/245.0
TSVEWEKSLSKNRSKNHKLNDNTRVILSPENTensrtDPPDTYINASHIKFDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVTIFEPQTDEAIEefr
.. ..... .|||...  ..|.|||.|||...     |. ..|||||......  . ||.||.|||.|| |||||.   ..| ||.. |.  .. .    
svallpenkdknrysdilpydhtrvklspdgg.....dldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvk...

nptltlaapaptstmttiggfpvpigqiahnrdqiqgqsircesnvhRSSFFPLetDHYMNLKGWLINTRRVTVdhrnKGWMNKYTVEVVAEGCSEATFA
                                                  ..||  ..... ... ........    ....  .|.||. .|..|  . 
...............................................caqywpl..gesltygdftvtllseeh....lddytvrtlevtnlgddesrev

KVYNCTTWPWKKYPDDEKKVLALVRAPYKDTSTslianlEKLAPIVVMCDLGLDRSATVVLTSIIIDQIIAGKTPDCDALFKKMRDQRAGVFTMSIFYTY
 .| .. ||  . ||. . .| ....  |  .        .  |..|.|  |..|..|...  ....|. . .. . .  .|..|.|| |....  .| .
ihyhylpwpdhgvpdllellldflefvrkalae......dsngpvlVHCsaGvgRtGtfiaaylmleqlekelgvsleeavkelrsqRpgavqtpsqyrf

AIRAALFYM
 ..|.|...
lyeallell

subfamily_PTPN5_RR_pd Subfamily PTPN5_RR 132-438 7.3e-28 92.4 In-house 25-270 (274) alignment
Range on Protein: 132-438
Range on HMM: 25-270/274.0
WEKSLSKNRSKNHKLNDNTRVILSPENTEnsrtDPPDTYINASHIK-FDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVTIFEPQ--TDEAIEEFRN
  .| .||| |.   |.|.||.|..|..|    |.  .|||| .|| .|. .| .. || ||| || |||||.   .|. || . . .    .  ...  
vfgsqtknryktilPnensrvllesesse....dedssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneqkCavyfP

ptltlaapaptstmttiggfpvpigqiahnrdqiqgqsircesnvhrssffpleT-------------DhymnlkgwlintrrvtVDHRNKGWMNKYTVE
                                                      .             .                .  ...   |.|.|.
......................................................daedyeiserygdve................ikvekiverndysvr

-VVAEGCSEATFAKVYNCTTWPWKKYPDDEKKVLALVRAPykdtSTSLIANLEKLAPIVVMCDLGLDRSATVVLTSIIIDQIIAGKTPDCDALFKKMRDQ
 .| . ...    | |  | || .| ||| ...| ||.      ..|  .. .||||.|| |  |. |    . .|| . |. . .. |   .  ..| .
klvlkylerersvkhywytdWPdhksPddantlldlvlev....eesreeenaklapvvvhCsaGiGrtGcfiaisiavrqlreeivvdvlkivcnlrld

RAGVFTMSIFYTYAIRAALFYMKI
| |.   |  | .  ||   |.| 
rGGmvqtseqyelihralclylkr

subfamily_Choan-PTP-2_pd Subfamily Choan-PTP-2 136-441 1e-21 72.2 In-house 21-269 (270) alignment
Range on Protein: 136-441
Range on HMM: 21-269/270.0
LSKNRSKNHKLNDNTRVILspentENSRTDPPDTYINASHIK-FDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVtqivtifepqtdeaieefrnptltla
   ||...   . .|||.|     |. ..|.  .|||| ... ||...|..| .. ||| |...||||.   ||                          
kklnRyadiLPsPatRvrl.....eeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekv..........................

apaptstmttiggfpvpigqiahnrD-QIQGQSIRCESNVHRSSFFPLETDHYMNLKGWLINTRRvTVDHRNKGWMNKyTVEVVAEGCSEATFakVYNCT
                            .    .  . . . . ..| |... ..|.   |...  . .....|.. .  ...  .| ..      .  .
.........................taivmttgleEkgrkkCerYWpaepkekvkledgkikvla.lseekeegyilt.rlrleekgeerrlv..Hfwyn

TWPWKKYPDDEK------KVLALVRApykdtSTSLIANLEKLAPIVVMCDLGLDRSATVVLTSIIIDQIIAGKTPDCDALFKKMRDQRAGVFTMSIFYTY
||| .  | .|       ..|...||           .|.|  |..| |  |..|. |.... |..  .   |  |. |. ...| .|  .   .  |..
tWpdhgvpreedsslstdqllkmlra.....vrrsekeldkaePllvHcsaGvgRtGtlialDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyef

AIRAALFYMKIKLQ
. .| . |.. ...
lykavveyaerrak

Y_phosphatase Protein-tyrosine phosphatase 136-219 1.8e-21 72.0 Pfam-A 2-78 (235) alignment
Range on Protein: 136-219
Range on HMM: 2-78/235.0
LSKNRSKNHKLNDNTRVILspenteNSRTDPPDtYINASHIKFDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVTIFEPQT
..|||.|.    |.||| |      .....| | ||||...|  ...|.||.|| ||..|. ||||||   ||. ||.. . . 
kkknRykdilpydktrvkl......kgsegpsd.YInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltslee

Y_phosphatase Protein-tyrosine phosphatase 136-219 1.8e-21 72.0 In-house 2-78 (235) alignment
Range on Protein: 136-219
Range on HMM: 2-78/235.0
LSKNRSKNHKLNDNTRVILspenteNSRTDPPDtYINASHIKFDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVTIFEPQT
..|||.|.    |.||| |      .....| | ||||...|  ...|.||.|| ||..|. ||||||   ||. ||.. . . 
kkknRykdilpydktrvkl......kgsegpsd.YInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltslee

subfamily_Cele-PTP-4_pd Subfamily Cele-PTP-4 276-442 2.8e-21 70.3 In-house 135-291 (302) alignment
Range on Protein: 276-442
Range on HMM: 135-291/302.0
SSFFPLETDHYMNLKGWLINTRRvtVDHRNKGWmNKYTVEVVAEGCSEATFAKVYNCTTWPWKKYPDDEKKVLALVRAPykdtstsLIANLEKLAPIVVM
| .||.... | . .   .|.|.  |.. ..   ..|..||. ||||.. .|.|| .| |. || |.   .. . .             . .  ...|..
selfpkksgdykeygkmfvNnrk..Vekaeeek.tryviEvlPegcsnsvlanvyvltnWkqkkvpvkyaeliktaakv.......fakkikadentviv

CDLGLDRSATVVLTSIIIDQIIAGKTPDCDALFKKMRDQRAGVFTMSIFYTYAIRAALFYMKIKLQT
   |  | ....   . .... .|| |    . |..| ||. .    . |.   .|.|.|.| |...
SknGaGRagafltlavaveklqkgkepnikeivksiRsqRpravdslkQyvslyialllyikkkvtk

0041856 (Phosphotyrosine protein) phosphatases II 136-440 2.8e-20 68.1 In-house 2-175 (182) alignment
Range on Protein: 136-440
Range on HMM: 2-175/182.0
LSKNRSKNHKLNDNTRvilspentensrtdpPDTYINASHIKFDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVTIFEPQTDEaieefrnptltlaa
|.||| ..   .|..|               . .||||. . ..  ...||.|| ||..|| ||.||.  ...| ||.. |.. .               
ldknrysdilpydhsr...............dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlteelywp..............

paptstmttiggfpvpigqiahnrdqiqgqsircesnvhrssffpletdhymnlkgwlintrrvtvdhrnkgwmnkytvevvaegcseA---TFAKVYNC
                                                                                                 | .
........................................................................................ellerlgiqyly

TTWPWKKYPDdEKKVLALVRAPYKdtstslianleKLAPIVVMCDLGLDRSATVVLTSIIIDQiiagkTPDCDALFKKMRDQRAGVFTMSIFYTYAIRAA
. ||    ||   ..|..... ..           .  |..| |  |..|..|.|.  ... .       . .  .| .| .| |....  .| .  .|.
lpwpDhgvpd.ldelldfieevle...........eggpvlVHCsaGvgRtgtlvaaylmkkl.....gvsleeavklvrsrRpgmvitpnqyfflqlal

LFYMKIKL
|.... | 
lellllkk

Y_phosphatase Protein-tyrosine phosphatase 273-432 3e-18 61.5 Pfam-A 82-233 (235) alignment
Range on Protein: 273-432
Range on HMM: 82-233/235.0
VHRSSFFPLETDHYMNLKGWLINTRrvtvdHRNKGWMNKYTVE--VVAEGCSE---ATFaKVYNCTTWPWKKYPDDEKKVLALVRAPYKDTstslianLE
.. . ..| |.. ... .   ....     ...| ....||..   . . ..|    .. |.. .|.|| .. |.. |..| |.|.  |..        .
ekcaqYwpeeeeesltygdikvelk.....ekekedekeytlrklelkkkkeesekrev.kqlhytnWpdhgvpespkslldlirkveksk.......ea

KLAPIVVMCDLGLDRSATVVLTSIIIDQIIAGKTPDCDALFKKMRDQRAGVFTMSIFYTYAIRAA
| .|.||.|  |  |..|.|. .|...|. |....|   . |..| ||.|...    | . ..| 
ksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmvqsleqYiflykai

Y_phosphatase Protein-tyrosine phosphatase 273-432 3e-18 61.5 In-house 82-233 (235) alignment
Range on Protein: 273-432
Range on HMM: 82-233/235.0
VHRSSFFPLETDHYMNLKGWLINTRrvtvdHRNKGWMNKYTVE--VVAEGCSE---ATFaKVYNCTTWPWKKYPDDEKKVLALVRAPYKDTstslianLE
.. . ..| |.. ... .   ....     ...| ....||..   . . ..|    .. |.. .|.|| .. |.. |..| |.|.  |..        .
ekcaqYwpeeeeesltygdikvelk.....ekekedekeytlrklelkkkkeesekrev.kqlhytnWpdhgvpespkslldlirkveksk.......ea

KLAPIVVMCDLGLDRSATVVLTSIIIDQIIAGKTPDCDALFKKMRDQRAGVFTMSIFYTYAIRAA
| .|.||.|  |  |..|.|. .|...|. |....|   . |..| ||.|...    | . ..| 
ksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmvqsleqYiflykai

subfamily_PTPRD_pd Subfamily PTPRD 126-214 4.1e-18 60.3 In-house 37-122 (564) alignment
Range on Protein: 126-214
Range on HMM: 37-122/564.0
NFTSV--EWEKSLSKNRSKNHKLNDNTRVILSPENTEnSRTDppdtYINASHIKFDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVTI
.||    . .   .||| .|    |..||.||. . . . .|    |||||.|.  ...|..| || ||..|..||||||   ... || .
qftweaankpaNkaKNRyanivaYdhsRVvLskvegd.egsD....YINAsfidgyrkrkayIAtqgPlaetiedFWRmvweqnsstiVml

PTPc_DSPc_SM00012 328-433 4.6e-18 60.7 In-house 3-104 (105) alignment
Range on Protein: 328-433
Range on HMM: 3-104/105.0
KVYNCTTWPWKKYPDDEKKVLALVRAPYKDTSTSLIanlekLAPIVVMCDLGLDRSATVVLTSIIIDQIIAG-KTPDCDALFKKMRDQRAGVFTMSIFYT
|.| .|.||... |.. ...| |.||  | .. |        .|.||.|  | .|..|.|. .|...|. .. |..|   ..|..|.||.|....   | 
khyhytgwpdhgvPeesdsilellravkknknkses.....skpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqyl

YAIRAAL
. .|| |
flyrall

subfamily_Ptp69D_pd Subfamily Ptp69D 132-216 8.7e-18 59.5 In-house 45-124 (307) alignment
Range on Protein: 132-216
Range on HMM: 45-124/307.0
WEKSLSKNRSKNHKLNDNTRVILSPENTENSRtdppdTYINASHIKFDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVTIFE
 .  . |||... |  |.|||.|.. | ...      .|||||.||  . .|.||. | |.  |. |||||..  .|| || . .
kkenalknRyedikafDktRvkLkkingkeds.....dYinasfikgykekkkfiaaqdPveatigDfWRmiaeqevtlivmlsn

subfamily_PTPRB_pd Subfamily PTPRB 134-214 1.4e-17 58.6 In-house 50-125 (293) alignment
Range on Protein: 134-214
Range on HMM: 50-125/293.0
KSLSKNRSKNHKLNDNTRVILSPENTEnSRTDppdtYINASHIKFDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVTI
.  .||| .|    |..|| |.. ..| | .|    ||||..|.  ||..|||.|| |||.|| ||||||   |.. || .
vnraknrytnilpydhsrvkLaalkde.sgsD....YinanyipgynsprefiatqGPlpetvddfWrmvwekkssiivml

subfamily_Anemone-PTP-2_pd Subfamily Anemone-PTP-2 134-214 1.7e-17 58.7 In-house 55-130 (298) alignment
Range on Protein: 134-214
Range on HMM: 55-130/298.0
KSLSKNRSKNHKLNDNTRVILSPENTENSrTDppdtYINASHIKFDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVTI
.  .|||  .    | .||.|. |....  .|    |||||...  . .. ||.||.||. || ||||||.  ... || .
enkkkNRyadiialdssRvvLekedadee.sd....YiNAsflhaykgrnafiatqaPltetvedFWrmvteedigtiVml

subfamily_Sponge-PTP8_pd Subfamily Sponge-PTP8 129-215 2.2e-17 58.2 In-house 39-121 (305) alignment
Range on Protein: 129-215
Range on HMM: 39-121/305.0
SVEW-EKSLSKNRSKNHKLNDNTRVILSPENTENsrtdpPDTYINASHIKFDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVTIF
 |.  |.. .|||.|.  | |. |.||.......        |||||...  ...|..||.| ||..||.||||..  .||..|| . 
dvgkkeankaknrlkeitlldddriiltekesld.....dsdyinasyvdgykrkkkyivaqgPlkntvadfWrliveekvstivmlt

subfamily_Sponge-PTP11_pd Subfamily Sponge-PTP11 134-220 2.5e-17 57.7 In-house 45-128 (290) alignment
Range on Protein: 134-220
Range on HMM: 45-128/290.0
KSLSKNRSKNHKLNDNTRVILSPENtenSRTDPPDTYINASHIKFDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVTIFEPQTD
..  .||..|  ..|. |..| | .   .. | .. ||||..||  . .|..|.|| |...|..|||...   ||| || . . . .
snkllnRfanivvyddnritLrpis...ghkDCtneyinAcyikgykekkqyiatqgpvsntlvdFWkliwqekvtiivmltniiee

0043147 (Phosphotyrosine protein) phosphatases II 165-428 5.6e-17 57.5 In-house 2-153 (172) alignment
Range on Protein: 165-428
Range on HMM: 2-153/172.0
DPPDTYINASHIKFDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVTIFEPqtdeaieefrnptltlaapaptstmttiggfpvpigqiahnrdqiqg
|....|||||....    ..||.||.||. |. |||||.  ...| ||.. |                                                
degsdyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltel...............................................

qsircesnvhrssffpletdhymnlkgwlintrrvtvdhrnkgwmnkytvevvaegcseA-------TFAKVYNCTTWPWKKYPdDEKKVLALVRAPYKD
                                                                    .   | .. ||    | . . .| ...  .. 
...........................................................lydpellerlgiqylylpwpDhgvp.llellleflefidel

TstsliaNLEKLAPIVVMCDLGLDRSATVVLTSIIIdqiiagKTPDCDALFKKMRDQRAGVFTMSIFYTYA
       .|..  |..| |  |..|..|.|.  ...      .  . .  .. .|..| |...   .| . 
l......alspggpvlVHCsaGvgRtgtlvaaylml......lglsleeavalvrekRpgavqnpsqyrfl

subfamily_PTPRG_pd Subfamily PTPRG 133-216 7.3e-17 55.8 In-house 45-124 (563) alignment
Range on Protein: 133-216
Range on HMM: 45-124/563.0
EKSLSKNRSKNHKLNDNTRVILSPENTENSRTDppdtYINASHIKFDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVTIFE
...  |||  |    |..|| |||   .... |    ||||..|.  . .|.||.||.||.||. |||||.   .|. ||.| .
penkrKnRylnivaydrsRvklsplpgkkkklD....YinAnyidGyqkskafiatqgplkdtfddFWrmiWeqnvaiivmitn

0037934 (Phosphotyrosine protein) phosphatases II 129-218 7.6e-17 57.1 In-house 4-83 (243) alignment
Range on Protein: 129-218
Range on HMM: 4-83/243.0
SVEWEKSLSKNRSKNHKLNDNTRVILspentensrtdPPDTYINASHIKFDNsqkEFIVTQYPLPDTVRD----FWRMVSIMKVTQIVTIFEPQ
   .. .||||| ..  ..|..||.|           ... ||||..|.  .    .|.||.|||.|| |    ||||.   ..| ||.. |..
iallpenlsknrysdilpydhsrvkl...........egsdyinanliyvtp...rliatqgPlpetveddlasfwrmlwelgitvivmltelv

subfamily_Urchin-PTP-4_pd Subfamily Urchin-PTP-4 126-417 3.1e-16 53.8 In-house 36-217 (392) alignment
Range on Protein: 126-417
Range on HMM: 36-217/392.0
NFTSVEWEKSLSKNRSKNHKLNDNTRVILspENTENSrtdPPDTYINASHIKFDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVTIFEPQTDEaiee
. |. . |  | ||| ||    |..||.|  |  ...   | . |.|||.|.  ...| .| .| | . .. ||||||   .|| |. . . .  .    
pqtvaqkeinlkknryknilpydsarvkl..eviddi...pdsdylnasyipsfdnekayiasqgpnaaslddfwrmvfqenvttiamvtklkegd....

frnptltlaapaptstmttiggfpvpigqiahnrdqiqgqsircesnvhrssffpletdhymnlkgwlintrrvtvdhrnkgwmnkytvevvaEGCSEAT
                                                                                              | .  |
.............................................................................................kgddart

FAKvYNCTTWPWKKYPDDEKKVLALVrapyKDTStsliANLEKLA-PIVVMCDLGLDRSATVVLTSIIIDQIIAGKTPDCDALFKKMRDQRAG
 |. .  | || |  |     .| ..    |. .    |.  . . |... |  |. |.. |.    .. .    .  |   .  ..| .|  
vaq.fhftewPdkdvpkhtssllkfi....kevk....adfGqythpliihcsagvgrtgvvisidsvvahakktrmvdvfnfvtnirrkrpy

subfamily_Choan-PTP-1_pd Subfamily Choan-PTP-1 133-214 6.6e-16 53.2 In-house 39-115 (281) alignment
Range on Protein: 133-214
Range on HMM: 39-115/281.0
EKSLSKNRSKNHKLNDNTRVILSPENTENsRTDppdtYINASHIKFDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVTI
..   ||| .|    |.||| ..|.....  ||    ||||....  ...||.|.|| |.|... .||.||   ||..|| .
denvlknrYsnivaYDatrvkvtpneenk.ntD....YinanfvpgykgekeyiatqgPvPaslvafWqmvweqkvsaivmv

subfamily_PTPN12_pd Subfamily PTPN12 131-213 7.2e-16 52.9 In-house 36-113 (290) alignment
Range on Protein: 131-213
Range on HMM: 36-113/290.0
EWEKSLSKNRSKNHKLNDNTRVILSPENTENsrtdpPDTYINASHIKFDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVT
| |.   ||| |.    |..|| || .. |.      . ||||..||  ....|.| .| |||.|. |||||.  ..|. .| 
ekeenvkknrykDilPydksrvelskieeee.....gsdYinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvm

subfamily_Anemone-PTP-5_pd Subfamily Anemone-PTP-5 120-215 9.5e-16 52.7 In-house 33-123 (319) alignment
Range on Protein: 120-215
Range on HMM: 33-123/319.0
AGYTPPNFTSVEWEKSLSKNRSKNHKLNDNTRVILSPENTENSrTdppdTYINASHIKFDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVTIF
 . .. .|.| . |.  .||| .| .  |.|||.||. .  .. .    .|||||.|   . ...|| || || .|. ||||||   ..  .| . 
keavndtfdsaskeenkkknryqnilaydrtrvvlseldgveg.s....dyinasfidgyqerekfiatqaPlentiedfWrmvWeeessivvmlt

subfamily_Anemone-PTP-6_pd Subfamily Anemone-PTP-6 136-214 1.2e-15 52.4 In-house 47-120 (318) alignment
Range on Protein: 136-214
Range on HMM: 47-120/318.0
LSKNRSKNHKLNDNTRVILSPENTENSrTDppdtYINASHIKFDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVTI
  |||  |    |.||| |.. ..|.. .|    ||||..|   ...|..| .| |||.|..||||||   . . ||..
kaknryanilaydhtrvkLqmlegeeg.sD....yinanyidGyrrkkayiaaqaPlpetieDfWrmvWeqnsavivml

subfamily_Urchin-PTP-1_pd Subfamily Urchin-PTP-1 128-221 2.8e-15 51.0 In-house 37-125 (315) alignment
Range on Protein: 128-221
Range on HMM: 37-125/315.0
TSVEWEKSLSKNRSKNHKLNDNTRVILspentENSRTDPPDTYINASHIKFDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVTIFEPQTDE
..   .   .||| ||    |..||.|     |    .| . |||||.||  ...| .| .| ||. .| ||||||   ||| || . . | ..
rvaretinfkknryknilPldsarvkl.....eviddsPdsdyinasyiksvdddkayiasqgPlkasvddfwrmvlqekvttivmvtkkqegd

0049772 (Phosphotyrosine protein) phosphatases II 133-437 3.7e-15 51.9 In-house 44-281 (314) alignment
Range on Protein: 133-437
Range on HMM: 44-281/314.0
EKSLSKNRSKNHKLNDnTRVILSPENTENsrtdppDTYINASHIKFDnsqKEFIVTQYPLPDTVRDF----------WRMV--SIMKVTQIVT-------
..  .|||...    | .||||. .. ..        |||||...     . ||.||.||. || ||          ||||  . ..|  ||        
flnrdknryldilpad.nrvilpglpvsg......sdyinasyvdgf...lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivmsrdevla

-----------------IFEPQtdeaieefrnptltlaapaptstmttiggfpvpigqiahnrdqiqgqS----------Ircesnvhrssffpletdhy
                 . ...                                               .                              
delsrLdaAlgKtpllildgng...............................................neptaadlellk...................

mnlkgwlintrrvtvdhrnkgwmnkytvevvaegcseatfakV-------YncttwpwkkypddEKKVLALVRAPYKDTSTSLIA----------NLEKL
                                                  .             |. .. ..| |  | |. |..          ...| 
..........................................eelydpelf.............erlgikylripvpDgsaplledfdeflefieeadkg

APIVVMCDLGLDRSAT-VVLTSIIIDQiiagKTpDCDALFKKMRDQRA-----GVFTMSIFYTYAIRAALFYMK
 |..| |  | .|..| ||.  ... .    .  . .  .. .| .|      | . . . | .  .| | |.|
gpvlvHCkaGkgRtgtfvvaaylmkll....gv.sleealedvrlkRpinpnpgfieqleqyefilealleylk

subfamily_Urchin-PTPRB-like_pd Subfamily Urchin-PTPRB-like 137-214 3.7e-15 50.7 In-house 49-121 (288) alignment
Range on Protein: 137-214
Range on HMM: 49-121/288.0
SKNRSKNHKLNDNTRVILSPENTENSrTDppdtYINASHIKFDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVTI
.||| .|    | .|| |   ..|.. .|    |||||.|. ....|..| || ||.||| |||..|   |.. || .
kknRyrnilpyDekrvklkkleeeag.aD....YinasyidgekkkkkyiatqgPladtvndfWelvyenktstivml

subfamily_Sponge-PTP10_pd Subfamily Sponge-PTP10 137-217 4.3e-15 50.5 In-house 49-120 (287) alignment
Range on Protein: 137-217
Range on HMM: 49-120/287.0
SKNRSKNHKLNDNTRVILSpentensrtDPPDTYINASHIKFDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVTIFEP
 |||...    || ||.|          .  . ||||..|.  ...|.||... |. .|.|.||...   .|| || . . 
dknRltqilvpdnyrvllk.........gehpdyinavfidgykekkafiiaesPmfntarnfWkliddrnvtaivmlcqe

subfamily_Nvec-PTP-2_pd Subfamily Nvec-PTP-2 135-214 4.5e-15 50.5 In-house 9-83 (250) alignment
Range on Protein: 135-214
Range on HMM: 9-83/250.0
SLSKNRSKNHKLNDNTRVILSPENTENsRTDppdtYINASHIKFDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVTI
 . |||  .    |..||.| .|....  .|    |||||...  . .| ||.|| ||..|. ||||||   |.. || .
nkeknryadiialdssrvvLekekgdk.esd....yinasflhgyderkafiatqgPlqatiedfWrmvleeksgtivmL

0036282 (Phosphotyrosine protein) phosphatases II 168-428 9.2e-15 50.2 In-house 2-162 (174) alignment
Range on Protein: 168-428
Range on HMM: 2-162/174.0
DTYINASHIKFDNSQKEFIVTQYPLPdtvrdFWRMVSIMKVTQIVTIFEPQTDE--AI-----Eefrnptltlaapaptstmttiggfpvpigqiahnrd
..|||||....    ...|..|.||.     ||.|.   ..| .|.  |.. ..   .     |                                    
sdyinaspldlsyitprliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe....................................

qiqgqsircesnvhrssffpletdhymnlkgwlintrrvtvdhrnkgwmnkytvevvaEGCSEATFAKVYNCTTWPWKKYPDDEKkVLALVRAPYKDTST
                                                             ..  .   | .. ||    ||... .| .|.. ..  | 
..........................................................lredlerlgiqylylpwpDhgvpdlsi.llefvkfveealse

slianlEKLAPIVVMCDLGLDRSATVVLTSIIIDQIIaGKTPDCDALFKKMRDQRAGVFTMSIFYTYA
       .  |..| |  |..|..|.|.  ... ...  .. |  .|....| || |....  .| . 
......dpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtpsQyrfl

subfamily_Sponge-PTP5_pd Subfamily Sponge-PTP5 135-222 1.6e-14 48.4 In-house 33-114 (283) alignment
Range on Protein: 135-222
Range on HMM: 33-114/283.0
SLSKNRSKNHKLNDNTRVILSPENTensrtdppdTYINASHIK---FDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVTIFEPQTDEA
   ||| ..    |. || | .|.          .||||..|     .. .|..|..| || .||.|||.||   |.| || . . | |. 
nkrknrnqeivpadqwrvelksesr.........dyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekitaivmltklqedlr

subfamily_PTPRK_pd Subfamily PTPRK 129-216 2.2e-14 48.0 In-house 37-119 (314) alignment
Range on Protein: 129-216
Range on HMM: 37-119/314.0
SVEWEKSLSKNRSKNHKLNDNTRVILSPENTensrtDPPDTYINASHIKFDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVTIFE
.   ..  .||||..    |..||.| . .      ||   ||||. |   .  ..|||||.||..||.||||.|   . . || . |
aakkdenreknrsgdilaydrsrvflitidg.....dpssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasivmlte

subfamily_Urchin-PTP-6_pd Subfamily Urchin-PTP-6 128-216 4.6e-14 46.4 In-house 36-119 (515) alignment
Range on Protein: 128-216
Range on HMM: 36-119/515.0
TSVEWEKSLSKNRSKNHKLNDNTRVILspENTENsrtDPPDTYINASHIKFDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVTIFE
|  . |   .||| ||    |..||.|  |  ..   .|   |.|||.|.  ...| .| .| |.. .| ||||.|   .|| |. . .
tvaqeeinfkknryknilPydsvrvkl..evind...nPhsdyfnasyipsfdndkayiasqgPnkasvddfWrlvlqenvttiamvtk

0046846 (Phosphotyrosine protein) phosphatases II 164-435 6.4e-14 47.6 In-house 8-172 (176) alignment
Range on Protein: 164-435
Range on HMM: 8-172/176.0
TDPPDTYINASHIKFDnsqkEFIVTQYPLPDTVRDFWRMVSIMKVTQIVTIFEPQTDEA------IEEFRNPTLtlaapaptstmttiggfpvpigqiah
 |.. .||||. |  .     .|.||.|||.|. ||..|.  ...| .|.. |..  .        .|.... .                          
ldldldyinanlilgs....rpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgi..........................

nrdqiqgqsircesnvhrssffpletdhymnlkgwlintrrvtvdhrnkgwmnkytvevvaegcseatfakVYNCTTWPWKKYPDDeKKVLALVRAPYKD
                                                                        | .. ||    ||. . .| |... .. 
.......................................................................qylhlpwpDhgvpdl.elllellefirea

TSTSlianleklAPIVVMCDLGLDRSATVVLtsiiIDQIIAGKTPDCDALFKKMRDQRA-GVFTMSIFYTYAIRAALFY
 .           |..| |  |. |..|.|.    .. .. .|  . .  ....|.||  |...   .| .  ...|..
lkeg........gpvlVHCsaGigRtgtlva....ayllelekglsveealalvreqRplgavqtpeQyrflyefelll

subfamily_Sponge-PTP9_pd Subfamily Sponge-PTP9 134-219 6.8e-14 46.3 In-house 39-121 (301) alignment
Range on Protein: 134-219
Range on HMM: 39-121/301.0
KSLSKNRSKNHKLNDNTRVILSPENTENSRTdppDTYINASHIKFDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVTIFEPQT
.    || || .  |. |.||.|... .. .    .|||||.|.  ...|.||..| |.  |..||||..   |...||.. . . 
enkalnrfknitvyddnriilkpkpnldlcq...reyinasyidgysekkkfiaaqgpmkktlvdfWrliwqekpvsivmvtnlke

subfamily_Urchin-PTP-5_pd Subfamily Urchin-PTP-5 132-217 9.7e-14 46.2 In-house 48-126 (297) alignment
Range on Protein: 132-217
Range on HMM: 48-126/297.0
WEKSLSKNRSKNHKLNDNTRVILSPENTensrtDPPDTYINASHIKfdNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVTIFEP
    ..|.| ||    |  ||.|   |.     ||   |.|||..|    ....| || | ..|| |||.||   .|. || . . 
kkvnfeksRYkniLPydssRvkLaivnd.....dpdsDyvnasfvk..gnkhrlittqmPmkatvadfWamvldeqvstivmlndd

0051429 (Phosphotyrosine protein) phosphatases II 168-438 1.1e-13 47.0 In-house 4-227 (272) alignment
Range on Protein: 168-438
Range on HMM: 4-227/272.0
DTYINASHIKFDNS---QKEFIVTQYPLPDTVRDFWRMvSIMKVTQIVTIFEPQTDEAIEEFRNPTltlaapaptstmttiggfpvpigqiahnrdqiqg
..||||....  ..    . .. ...||| |..||||.   .... ||.. ..   ..   .| .                                   
sgyiNardvggygrvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywp..................................

qsircesnvhrssffpletdhymnlkgwliNTRRV--------------------TVDHRNKGWMNKYTVEVVAE-GCSEATFAKVYNCTTWPWKKYPDD
                              . |..                    ..   ..  .  .. ... . . .||    .. .| ||   .|..
..............................girylhlpilddsaptilygalrvtllseellldyilrellltlllsagearevmhlhytdwpdhgvpqe

EkkVLALVRAPYKdtstslianlekLAPIVVMCDLGLDRSATVVLTSIIIDQIIAGKTPD--------CDALFKKMRDQRAGVFTMSIFYTYAIRAALFY
.  .|.|...  .              |..| |  | ||..|||.  ... .. .    |         ..  ...|.||.|..    .| .  .|.| .
a..llellellld............ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlyleeaveelraqrpgavqteeqylflyeallel

MKI
.. 
lrs

subfamily_PTPRA_pd Subfamily PTPRA 127-216 1.3e-13 45.6 In-house 50-134 (330) alignment
Range on Protein: 127-216
Range on HMM: 50-134/330.0
FTSVEWEKSLSKNRSKNHKLNDNTRVILSPENTENSrTDppdtYINASHIKFDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVTIFE
.   . |.   |||  |   .| .|||||. . ... .|    |||||.|.  . ...|| .| |. .|| |||||.   | . || . |
lelaskeenkeknrvvnilPydfsrvilsvkeGvee.sd....yinasfidGykekdkfiaaqGPkeetvedfwrmiweqksativmlte

subfamily_PTPN9_pd Subfamily PTPN9 127-214 1.4e-13 45.6 In-house 34-116 (297) alignment
Range on Protein: 127-214
Range on HMM: 34-116/297.0
FTSVEWEKSLSKNRSKNHKLNDNTRVILSPENTENsRTDppdtYINASHIKFDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVTI
|. ..    |.||| ..    |.||| |. .. ..  .|    ||||...   . .| || || ||. ||.||||||   .|  || .
flasklranleknrytdvlcydetrvvlakvdede.asd....yinanfvdGykqkkafiatqGplkktvsdfWrmvWeqevlvivmt

0049260 (Phosphotyrosine protein) phosphatases II 177-427 1.5e-13 46.2 In-house 3-141 (152) alignment
Range on Protein: 177-427
Range on HMM: 3-141/152.0
KFDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVTIFEPQTDEAIEEFRNPtltlaapaptstmttiggfpvpigqiahnrdqiqgqsircesnvhrs
.. . ..||| ||.|.| |. |||||.  ...| ||.. |.. .  . . . .                                               
dgyampfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi...............................................

sffpletdhymnlkgwlintrrvtvdhrnkgwmnkytvevvaegcseatfakVYNCTTWPWKKYPDDEKKVLALVRAPYKDtstsliaNLEKLAPIVVMC
                                                     | .. ||    ||..  .| |...  |        .|.|  |..| |
....................................................qylhlpwpDhgvpdlsqlllflllfiekl.......aldkggpvlVHC

DLGLDRSATVVLTSIIIdqiiagKTPDCDALFKKMRDQRAGVFTMSIFYTY
  |..|..|.|.  ...      .  . .  .. .| .| |...   .. .
saGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpgqlrf

subfamily_PTPN6_pd Subfamily PTPN6 135-212 2.2e-13 44.9 In-house 54-127 (306) alignment
Range on Protein: 135-212
Range on HMM: 54-127/306.0
SLSKNRSKNHKLNDNTRVILSpentenSRTDPPDTYINASHIK--FDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIV
  .||| ||    |.|||||.      .   | ..||||. ||  . .|.|..| ||  |..|| ||||||   . . ||
nkeknryknilPfDhtrvilk......epsvpgsdyinanyikkevkgsdksyiatqgclettvsdFWrmvwqensrviv

subfamily_PTPN23_pd Subfamily PTPN23 136-218 2.7e-13 44.4 In-house 44-118 (288) alignment
Range on Protein: 136-218
Range on HMM: 44-118/288.0
LSKNRSKNHKLNDNTRVILSpentensrtDPPDTYINASHIKF-DNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVTIFEPQ
 .||||..    |..|| |          .  | |||||..|       .||.|| ||. |. |||.||   |.  || . ...
seknrsrdilPyDhnRvklr.........gskDDYinAsfvkdlspgcPdfiatqaPlqstlnDFWlmvyeqkssviVmllske

subfamily_Urchin-PTP-3_pd Subfamily Urchin-PTP-3 133-213 4.7e-13 44.0 In-house 46-121 (325) alignment
Range on Protein: 133-213
Range on HMM: 46-121/325.0
EKSLSKNRSKNHKLNDNTRVILSPEntensRTDPPDTYINASHIKFDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVT
 .  .||| ||    |..||.|        . ||   |||||... |  .. |. .| ||..|. |.||.|   . . .| 
penkaknrfknvvaldksrvvletk.....kddpssdyinasylrddkkkdvflaaqaPltatindlWrlvldWrcsvvvv

subfamily_PTPN14_pd Subfamily PTPN14 128-216 9.9e-13 42.7 In-house 42-126 (300) alignment
Range on Protein: 128-216
Range on HMM: 42-126/300.0
TSVEWEKSLSKNRSKNHKLNDNTRVILSPENtENsRTDppdtYINASHIKFD--NSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVTIFE
.. . ..  .||| |.    ...|| ||| . || .|.    |||||.||     .....||.| ||. ||.|||.||   .|. || . |
staklpenaeknrfkdvlPyednrvelsptk.en.stg....yinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivmlte

subfamily_PTPN13_pd Subfamily PTPN13 134-216 1.4e-12 42.5 In-house 36-110 (273) alignment
Range on Protein: 134-216
Range on HMM: 36-110/273.0
KSLSKNRSKNHKLNDNTRVILSPENTensrtdppdtYINASHIKF--DNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVTIFE
.  .||| .|    |.|||.|. | .          |||||.||   .. . |.|..| |||.||.|||.||   |.. |. .  
enkdknryrnvlPydetrvklgdegg..........yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamvtl

subfamily_Choan-PTP-4_pd Subfamily Choan-PTP-4 115-219 1.8e-12 41.7 In-house 13-112 (297) alignment
Range on Protein: 115-219
Range on HMM: 13-112/297.0
FDEHLAGYTPPNFTSVEWEKSLSKNRSKNHKLNDNTRVILSPENTENsrtdppdTYINASHIKFDNSQKE--FIVTQYPLPDTVRDFWRMVSIMKVTQIV
 |  |    . .|.|   . || ||| ..    |.||| |    ||.        |||| .. | . ...  .|..| || .|| |||..|    |  ||
kdllldeargesfssakrnsslrknryrdilatddtrvkllrviter.......dyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrviv

TIFEPQT
 . . | 
mvaklqe

subfamily_Choan-PTP-3_pd Subfamily Choan-PTP-3 127-216 3.3e-12 40.8 In-house 30-113 (287) alignment
Range on Protein: 127-216
Range on HMM: 30-113/287.0
FTSVEWEKSLSKNRSKNHKLNDNTRVILSPENTENSrtdppdTYINASHIKFDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVTIFE
| . |   . .|||  .    |.|||.|| |    |       |||| ..   . ...||..| |.. |||||||.|   ... ..|.  
fkaaeelaavkknryadvlPiddtrvllsaegelGs......dyinanyvasytddeafiaaqgPiaatvrdfwravletrsasvitmtr

subfamily_Urchin-PTP-7_pd Subfamily Urchin-PTP-7 136-214 3.6e-12 40.9 In-house 50-123 (315) alignment
Range on Protein: 136-214
Range on HMM: 50-123/315.0
LSKNRSKNHKLNDNTRVILSpeNTENsrtDPPDTYINASHIKFDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVTI
  |||  |    |..|| |    .||   ||   |.||. |.  | .. .| .| |.. .|.||||.|   ....|| .
kqknryiniiaydksrvqlp..llen...dphsdyvnanfidGynkkrryiaaqgpnvasvkdfwrlvfeedigkivml

subfamily_Cele-PTP-20_pd Subfamily Cele-PTP-20 111-216 4.4e-12 40.3 In-house 29-127 (290) alignment
Range on Protein: 111-216
Range on HMM: 29-127/290.0
LSTYFDEHLAGYTPPNFTS-VEW--EKSLSKNRSKNHKLNDNTRVILSPENtensrtdpPDTYINASHIKFDNsqKEFIVTQYPLPDTVRDFWRMVSIMK
|.  . |.|  | | ..     .  .  . ||| |.   || |||||.           .  |. | ..|  .    ||.|| .| ||| |.||||   |
lakeyleklkpylpvqylerkifdkntefkknrykdvvcndktrvilkdGy........dGdyvhanyvkGlk..amfiltqGalkdtvidiwrmvlqek

VTQIVTIFE
|. || . |
vaaivmlce

subfamily_Cele-PTP-15_pd Subfamily Cele-PTP-15 107-216 6.5e-12 40.0 In-house 7-111 (285) alignment
Range on Protein: 107-216
Range on HMM: 7-111/285.0
KEASLSTYFDEHLAGYTPPNFTSVEWEKSLSKNRSKNHKLNDNTRVILSpeNTEnsRtDppdtYINASHIKFD-NSQKEFIVTQYPLPDTVRDFWRMVSI
|  ..|  ..... || ||| |   .|     ||  . .  ..|||.|   | .  | |    || || ...  . |  .| || |||.|. |||.|.  
kcqaisklhqdkikgymppnctytayeanpdlnryadvrcieetrvvlk..nhd..r.d....yihaswmrmpgkdqstyittqgplpetlsdfwhmiyq

MKVTQI---VTIFE
 |.. .   .|.||
ekiayvlmlctlfe

subfamily_Urchin-PTPRA_pd Subfamily Urchin-PTPRA 128-214 8.1e-12 40.1 In-house 56-135 (319) alignment
Range on Protein: 128-214
Range on HMM: 56-135/319.0
TSVEWEKslSKNRSKNHKLNDNTRVILSPENTENSRtDppdtYINASHIKFDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVTI
. .. .|   |||  |    |...| | . . |.   |    |||||...   ... .| .| ||..|. |||||.  .... || .
anldqnk..dknriinilafdknvvklerliGeefs.d....yinasfvtGyqrkdkyiaaqGPldntladfWrmiweyncstivll

subfamily_Urchin-PTP-8_pd Subfamily Urchin-PTP-8 135-214 8.4e-12 40.2 In-house 25-99 (284) alignment
Range on Protein: 135-214
Range on HMM: 25-99/284.0
SLSKNRSKNHKLNDNTRVILSPENTENSRtDppdtYINASHIKFDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVTI
   |||  .    |...| | .   |.   |    |||||.|.   ... .| || ||..|. |||||.  .... || .
nkdknrighilafdknvvklerliGeefs.d....yinasfitGyqrkdkyiatqGPldntladfWrmiweyncstivll

subfamily_Sponge-PTP1_pd Subfamily Sponge-PTP1 134-231 1.7e-11 38.6 In-house 27-119 (267) alignment
Range on Protein: 134-231
Range on HMM: 27-119/267.0
KSLSKNRSKNHKLNDN-----TRVILSPENTEnsrtdppdtYINASHIKFDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVTIFEPQTDEaIEEFRN
.|....  . ..|.||     |||||. .. |         |||||...  . .. ||||| ||  |. ||. ..   ||. || .    ||. |  |  
qsiaeknqernrlddnlpyddtrvilrtkeee.........yinasyvegyktknafivtqdplkntitdfltvihdqkvpvivlltkvftdn.irlfwP

PTL
| .
Pkm

subfamily_PTPN1_pd Subfamily PTPN1 135-212 1.7e-11 38.3 In-house 32-100 (290) alignment
Range on Protein: 135-212
Range on HMM: 32-100/290.0
SLSKNRSKNHKLNDNTRVILspENTENsrtdppdTYINASHIKFDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIV
  ..|| .. .  | .|..|  |...|        ||||| ..... ....|.|| |||.||  ||.||   |   .|
nrnlnryrdvspydhsrikl..eradn.......dyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskavv

subfamily_PTPRN_pd Subfamily PTPRN 130-221 3.9e-11 37.2 In-house 51-138 (297) alignment
Range on Protein: 130-221
Range on HMM: 51-138/297.0
VEWEKSLSKNRSKNHKLNDNTRVILSPENTENSrtdppDTYINASHIK-FDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVTIFEPQTDE
 . || ..|||||.    |..|| |. |.....     . ||||| |   |  .  .| || ||..|| |||.||    |. ||.. . . ..
akaeknvkknrskavlpydhsrvklkeeasaek.....sdyinasaildhdprapayiatqgplastvadfwqmvweqGvvvivnltrleeeg

subfamily_PTPN3_pd Subfamily PTPN3 133-213 4.1e-11 37.3 In-house 39-114 (280) alignment
Range on Protein: 133-213
Range on HMM: 39-114/280.0
EKSLSKNRSKNHKLNDNTRVILSpenteNSRTDppdtYINASHIKFDNSQ----KEFIVTQYPLPDTVRDFWRMVSIMKVTQIVT
 . ||||| ..    |.|||.|.     .|.||    ||||......       . .|.|| ||..|. |||.||   |.. || 
penlsknryrdilpydatrvklk.....esetd....yinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqksslivm

subfamily_Cele-PTP-4_pd Subfamily Cele-PTP-4 131-226 4.4e-11 36.8 In-house 47-137 (302) alignment
Range on Protein: 131-226
Range on HMM: 47-137/302.0
EWEKSLSKNRSKNHKLNDNTRVILSPEntensrtdpPDTYINASHIKFDNSQKEFIVTQYPLPDTV---RDFWRMVSIMKVTQIVTIFEPQTD-EAIEEF
 . | |.||.|.. .. |...|.|. |         || |.|||...  . ... |..| |  |..    .|||||   |....| .  ...  ....|.
afkknlkknqsedvpildsnlvkleae.........pdsyvnaskvevPeltrsiilaQlpkvdsedsveeFWrmvfqekivsvvilvgeeelkktlsel





subfamily_egg_pd Subfamily egg 132-215 4.8e-11 36.9 In-house 37-115 (307) alignment
Range on Protein: 132-215
Range on HMM: 37-115/307.0
WEKSLSKNRSKNHKLNDNTRVILspentENSRTDPPDTYINASHIKFDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVTIF
 .  | | |||  . .| .|| |     |  |    | .| | ..| .    |||..| || .|| ||||||   .|  || . 
sdnnlekarskrvhckdssrvkl.....elrrGqylddfihanrvkGkpllnefilaqaplkntvddfwrmvfqeevqyivmlt

0037934 (Phosphotyrosine protein) phosphatases II 321-435 6.9e-11 37.6 In-house 129-241 (243) alignment
Range on Protein: 321-435
Range on HMM: 129-241/243.0
CSEATFAKVYNCTTWPWKKYPDDEKKVLALVRAPYKDTST--SLIANLEKlAPIVVMCDLGLDRSATVVLTSIIIDQIiagkTPDCDALFKKMRDQRAG-
  .  .   | .. ||  . ||. . .|..... ..  .   ||.|. ..  |..|.|  |..|..|...  ......    . | .  .|..|.|| | 
ddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsg.gpvlVHCsaGvgRtGtliaaylmllll....gvdleeavkllreqRpgk

VFTMSIFYTYAIRAALFY
...   .| . ..|.|..
avqtpsqyrflyeallel

subfamily_Anemone-PTP-6_pd Subfamily Anemone-PTP-6 299-428 7.8e-11 36.6 In-house 146-272 (318) alignment
Range on Protein: 299-428
Range on HMM: 146-272/318.0
VTVDHRNKGWMNKYTV---EVVAEGCSEATFAKVYNCTTWPWKKYPDDEKKVLALVRApykdtsTSLIANLEKLAPIVVMCDLGLDRSATVVLTSIIIDQ
..|. ...  ...|..   .|  ....|    . |..|.|| .  |..  ..|.|||       .| . . ..  |||| |  |  |  . .  .|....
lvvelkeevelsdyvlrefkvtrteeeesrqvrqyhytsWpdegvpesgaslldlvrq......vskaqqksgagpivvhCsaGvGrtGvfiavdiller

IIAGKTPDCDALFKKMRDQRAGVFTMSIFYTYA
| | .. |     |..|.||  .      |.. 
ikaealvDvfqtvkqlreqrnlmvqtedqyefi

subfamily_Cele-PTP-16_pd Subfamily Cele-PTP-16 109-215 1.2e-10 35.5 In-house 21-115 (303) alignment
Range on Protein: 109-215
Range on HMM: 21-115/303.0
ASLSTYFDEHLAGYTPPNFTSVEWEKSLSKNRSKNHKLNDNTRVILSpentensrtDppDTYINASHIKFDnSQKEFIVTQYPLPDTVRDFWRMVSIMKV
| ...   |....| ||. .  .. | . |||  .    | ..| ||         |   .|| ||....| |.|  |.|| ||. |  |||.|.   ||
aniavnefekvvsylppsvsknqfvknmdknrfvdvicldhskvkls.........d..ssyihasyleld.sskkailtqlplshtaadfwqmiieqkv

TQIVTIF
  .. ..
kcvllll

subfamily_Ptp69D_pd Subfamily Ptp69D 330-437 1.4e-10 35.8 In-house 187-287 (307) alignment
Range on Protein: 330-437
Range on HMM: 187-287/307.0
YNCTTWPWKKYPDDEKKVLALVRAPYKDTSTSlianlekLAPIVVMCDLGLDRSATVVLTSIIIDQIIAGKTPDCDALFKKMRDQRAGVFTMSIFYTYAI
|. |.|.  | |.  . .| |..  ..  ...        .|||| | .| .||...|  .....|. | .. |  .  |..| ||  ...    |..  
yhytgWkDskvPevargllklieqvrelykln.......rsPivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnllvqsleqYvfly

RAALFYMK
|| | |..
ralldyss

subfamily_PTPN6_pd Subfamily PTPN6 329-442 1.6e-10 35.5 In-house 190-303 (306) alignment
Range on Protein: 329-442
Range on HMM: 190-303/306.0
VYNCTTWPWKKYPDDEKKVLALVRAPYKDTSTSLIAnleKLAPIVVMCDLGLDRSATVVLTSIIIDQIIAGKT---PDCDALFKKMRDQRAGVFTMSIFY
 |. ..|| .  | | . ||....   . ....  |   .  |||| |  |. |  |.... |....|   ..    |   | |..|.|| |.  .   |
qyhfksWPdhgvpkdpgavLdfledvnrkqeeleea...eagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqteqqy

TYAIRAALFYMKIKLQT
 .  .|  .|.. | ..
kfvykaikkyietkkkl

subfamily_Fungi-PTP1_pd Subfamily Fungi-PTP1 135-214 1.9e-10 35.0 In-house 47-135 (350) alignment
Range on Protein: 135-214
Range on HMM: 47-135/350.0
SLSKNRSKNHKLNDNTRVILS----PENTENSRTDPPDtYINASHIKFD------NSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVTI
. .||| ||    . .||.|     . .. .  . . | ||||...|        |..  .| || ||| || ||....   ||. |...
lfaknrYknilPYehsrvkLkkslkssdakkhslstnD.YinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsl

subfamily_CG7180_pd Subfamily CG7180 136-216 3.8e-10 33.9 In-house 43-118 (296) alignment
Range on Protein: 136-216
Range on HMM: 43-118/296.0
LSKNRSKNHKLNDNTRVILSPENTENSrtdppDTYINASHIKFDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVTIFE
. |||  .    |..||.|.  . |..     . ||||...     .||.|||. |  .|| .|||.|   ..  .| . .
reknrdvkvvPyDynRvvLekldGeek.....sdYinavyvdsflkkkeyivteapkketvdefWrlvydeeisavvvLtk

0044763 (Phosphotyrosine protein) phosphatases II 160-431 9.1e-10 34.0 In-house 10-166 (178) alignment
Range on Protein: 160-431
Range on HMM: 10-166/178.0
ENSRTDPPDTYINASHIKfDNsqkeFIVTQYPLpdtvRDFWRMVSIMKVTQIVTIFEPQT-------DEAIEEFRnptltlaapaptstmttiggfpvpi
.| .  .   |||||.|  ..    ......|      |.....  ...| ||.. |..         .. ||.                          
snleglersdyinaseil.pg....lylgslpp....addlellkelgithivnlteelelgflkcdpywpeeag.........................

gqiahnrdqiqgqsircesnvhrssffpletdhymnlkgwlintrrvtvdhrnkgwmnkytvevvaegcseatfaKVYNCTTWPWKKYPDDEKKVLALVR
                                                                             | .. .|  . ||  . .|..|.
...........................................................................iqylhipipDhgvpdllehflefve

APYKDTstsliaNlEKLAPIVVMCDLGLDRSATVVLTSIIIDQiiagkTPDCDALFKKMRDQRAgVFTMSIFYTYAIRA
.  .        . ||  |..| |  |..||.|.|.  ... .       . .. .. .| .|  ...   .. . .. 
fieeal......d.ekggpvlVHCsaGvgRsgtlvaaylmkkl.....glsleeaielvrerRp.ivpnpgqlrqLyef

subfamily_ptpA1_pd Subfamily ptpA1 131-213 1.9e-09 31.7 In-house 43-119 (418) alignment
Range on Protein: 131-213
Range on HMM: 43-119/418.0
EWEKSLSKNRSKNHKLNDNTRVILSPENTENSrTDppdtYINASHIKFdNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVT
. ..  ||||  |    . ||| |   . ..  .|    |||| .|      |.||.|| |||.|. ||||||   ..  || 
dkkhntsknrytnilpvnhtrvqlkkiqdkeg.sd....yinanyidg.aypkqfictqgplpntiadfwrmvwenrcriivm

subfamily_PTPRD_pd Subfamily PTPRD 313-437 2e-09 31.7 In-house 165-282 (564) alignment
Range on Protein: 313-437
Range on HMM: 165-282/564.0
TVEVVAEGCSEATFAKVYNCTTWPWKKYPDDEKKVLALVRAPYKDTStslianlEKLAPIVVMCDLGLDRSATVVLTSIIIDQIIAGKTPDCDALFKKMR
| ..  .  ||.   . .. | || .  |.  ...|.|.|   . ..       ..  |||| |  |  |. | .  ......| . || |     |..|
tfklkkkkssesreVrqFhFtsWPdhgvpesatslLdlirkvralne.......pdagPivVhCSaGVGRTGtfividamlerikeektvDiyqyvkalr

DQRAGVFTMSIFYTYAIRAALFYMK
 ||  .      | .  .| | ...
kqRnamVqteeQYiFiheaileala

subfamily_Urchin-PTPRB-like_pd Subfamily Urchin-PTPRB-like 299-433 2.6e-09 31.5 In-house 148-276 (288) alignment
Range on Protein: 299-433
Range on HMM: 148-276/288.0
VTVDHRNKGWMNKYTVEVVAEGCSEAT-FAKVYNCTTWPWKKYPDDEKKVLALVRApYKdtstslIANLEKLAPIVVMCDLGLDRSATVVLTSIIIDQII
|||  ...  ....... .  . ..     . |. ..|| .. |.... .|.|.|   |      .|| ... ||.| |  |. |. | .    .||.. 
vtvtlveskeledfvlrklllekkkteleitqyqylaWpdhgvPeskapllellrq.vk......vanqadtgpiivhCsaGvGrtgtFialdalidave

AGKTPDCDALFKKMRDQRAGVFTMSIFYTYAIRAAL
. .. |  .  .|.| ||| .      | .  .. |
eedyiDvagtvaklRkqRallvqtlkqYefiyevll

subfamily_Fungi-PTP2_pd Subfamily Fungi-PTP2 138-214 2.7e-09 30.8 In-house 51-138 (349) alignment
Range on Protein: 138-214
Range on HMM: 51-138/349.0
KNRSKNHKLNDNTRVIL-----SPENTENS----RTDPPDTYINASHIKFD--NSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVTI
||| |.    . .||.|     |.. ...|     .  .| |||| ..|.   . .| .| || ||| || ||....   .|  .. .
knrykdilPyehsrvklkkslksskvikastsesdsgklddyinanylkltrisvekkyiatqaPlPstvddfykvillngvklvlsL

subfamily_Cele-PTP-10_pd Subfamily Cele-PTP-10 97-214 3.2e-09 30.8 In-house 12-127 (305) alignment
Range on Protein: 97-214
Range on HMM: 12-127/305.0
KGFCKYLLDIKEASLSTYFDeHLAGYTPPNFTSVEWEKSLSKNRSKNHklNDNTRVILSPENTENSRTDPPDTYINASHIKFDN-SQKEFIVTQYPLPDT
. | .  ||.    |   |  .|| || |..| | ..   | . .. .  |  . |    ... .    .|  || | ..      .| ||..| || .|
eqfvlraldvgvdklreefr.glakytrpdmtqvafnanqsadiaitk..nryqdvpcqdqsavkldkpspsdyihanyvgcpmipekrficaqgpldqt

VRDFWRMVSIMKVTQIVTI
. .|| ||   || ||| .
idefwwmviqnkveqivml

subfamily_Sponge-PTP6_pd Subfamily Sponge-PTP6 133-214 3.5e-09 30.6 In-house 46-122 (439) alignment
Range on Protein: 133-214
Range on HMM: 46-122/439.0
EKSLSKNRSKNHKLNDNTRVILSpenteNSRTDPPDTYINASHIKFDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVTI
| . .||| |.    | |||.|      .    |   |||| .||    .| .| ||.|  .|. ||||.|   |...||..
eydqtknrykdvgafdhtrvtlq.....eipgvphshyinanyikGyyddklyiatqgpkkettddfwrlviekktvtivml

subfamily_Cele-PTP-14_pd Subfamily Cele-PTP-14 127-212 3.9e-09 30.5 In-house 44-123 (310) alignment
Range on Protein: 127-212
Range on HMM: 44-123/310.0
FTSVEWEKSLSKNRSKNHKLNDNTRVILSpenTENSRTDppdTYINASHIKFDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIV
.|   ..| . |||  .    |..|| |     ..|| .    || | ..| .  .. ||..| ||  |. |||||.   .   |.
ltyeaykkymhknrysdvvcldtsrvklk...idksrye...dyihanyvktnylrstficsqgplqhtiidfwrmifqeraesil

subfamily_Anemone-PTP-4_pd Subfamily Anemone-PTP-4 137-213 5e-09 30.7 In-house 5-75 (237) alignment
Range on Protein: 137-213
Range on HMM: 5-75/237.0
SKNRSKNHKLNDNTRVILSPENTEnsrtdppDTYINASHIK-FDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVT
 |||  | .  | .||.|    ..         ||||...| || . |..| .| ||  .  |||.||   | . || 
iknrygnivaydhsrvvlkgagsg.......sdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivm

subfamily_PTPN13_pd Subfamily PTPN13 305-436 5.4e-09 30.7 In-house 146-269 (273) alignment
Range on Protein: 305-436
Range on HMM: 146-269/273.0
NKGWMNKYTVEVVAEGCSEATFAKVYNCTTWPWKKYPDDEKKVLALVRApykdtsTSLIANleKLAPIVVMCDLGLDRSATVVLTSIIIDQIIAGKTPDC
..  ..  ...|     .|.      | ..||  . |   ...| .|.          ...  . .|||| |  |. || |..   .... |   |  | 
kldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaellqfvae......vrrlqt..dagPivvhcsaGiGrsGtlitidvvlglierdkefdv

DALFKKMRDQRAGVFTMSIFYTYAIRAALFYM
  . .|.|.|| ||   .  | .  .|.|  .
keivrklreqrqgvvqtkdqyifvykailevl

subfamily_Anemone-PTP-2_pd Subfamily Anemone-PTP-2 306-436 5.7e-09 30.6 In-house 166-290 (298) alignment
Range on Protein: 306-436
Range on HMM: 166-290/298.0
KGWMNKYTVEVVAEGCSEATFAKVYNCTTWPWKKYPDDEKKVLALVRAPYKdtSTSLIanleKLAPIVVMCDLGLDRSATVVLTSIIIDQIIAGKTPDCD
.. . . ...|  .  ..    .  . |.|| |  |  .. ||.|.|   .  |..      . .|..| |  | .|| | .  . ..... . .. |  
fadlivrklkvskkkeekerevrqlhftsWpdkgvpenatsvldllrkvra..sqqqa....gnkpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvf

ALFKKMRDQRAGVFTMSIFYTYAIRAALFYM
   | .| .|.|. .    |..   | | ..
qvvkvlRkkrpgavqteeqYvfiyeavleal

subfamily_Cele-PTP-18_pd Subfamily Cele-PTP-18 312-438 6e-09 30.1 In-house 172-289 (305) alignment
Range on Protein: 312-438
Range on HMM: 172-289/305.0
YTVEVVAEGCSEAT-FAKVYNCTTWPWKKYPDDEKKVLALVRApykdtstsliaNLEKLAPIVVMCDLGLDRSATVVLTSIIIDQIIAGKT-PDCDALFK
   ..| ||  | .  .. |    || .  |  .  .| |.                   |||| |  |. |. .||.   |.||..||.   |.| ...
tetvlviegpgekarkvthyhwidwpdrgvpaadlailellek...........arpskgpivvhcsagigrtgsvvmleyildqllagqiiedtdkilq

KMRDQRAGVFTMSIFYTYAIRAALFYMKI
|.|.||         | .  .  | |.. 
kireqrnnsiqtdaqylfvhqvilnyfrk

subfamily_Cele-PTP-10_pd Subfamily Cele-PTP-10 353-439 7.2e-09 29.7 In-house 204-292 (305) alignment
Range on Protein: 353-439
Range on HMM: 204-292/305.0
APYKDTSTSLIANLE-KLAPIVVMCDLGLDRSATVVLTSIIIDQIIAGK-TPDCDALFKKMRDQRAGVFTMSIFYTYAIRAALFYMKIK
 | | ||  |.. .     |||| |  |. |. |.|    |...|   |  |    | | .|||||      . | .  |  | |.  |
ppckltslellsairgskvpivvhcsagigrtgtivaieyilekiaenkpcppmpelvkalrdqrafsiqndvqylfihrvmlnyflek

subfamily_Cele-PTP-6_pd Subfamily Cele-PTP-6 104-214 9.2e-09 29.7 In-house 11-113 (307) alignment
Range on Protein: 104-214
Range on HMM: 11-113/307.0
LDIKEASLSTYFDeHLAGYTPPNFTSVEWEKSLSKNRSKNHKLNDNTRVILSPENTensRTDppdtYINASHIKFDNSQKEFIVTQYPLPDTVRDFWRMV
||    .|   |   || .||   |   ..    ||| .. |  |..|...  .      .|    || | ..      | ||..| || .|. .|| |.
ldkgvqalvdefr.vlakktpegvtveafsantdknryqdvkcqdkgrivvkfdgl...asd....yihanylgiaikpkkficaqgplentqysfwama

SIMKVTQIVTI
   ||  .. .
iqekvesviml

subfamily_Sponge-PTP4_pd Subfamily Sponge-PTP4 161-212 1e-08 29.1 In-house 115-166 (244) alignment
Range on Protein: 161-212
Range on HMM: 115-166/244.0
NSRTDPPDTYINASHIKFDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIV
 |.    .|||||| .       |.|.||.|| ||  |||.|.   .|  .|
lskgsmgntyinasfvgclgrtaeyiltqhpladtsmdfwkmmlerhvnvlv

subfamily_Cele-PTP-5_pd Subfamily Cele-PTP-5 277-421 1e-08 28.2 In-house 161-294 (346) alignment
Range on Protein: 277-421
Range on HMM: 161-294/346.0
SFFPLETDHYMNLKGWLINTRRVTVDhrnkGWMNKYTVEVVAEGCSEATFAKVYNCTtwPWKKYpDDEKKVLALVRAPYKDTSTSLIANleklAPIVVMC
|.|  |   |      .|| ||  |     |  ..||.||. || |..  ..|.  .  |||.  ..  | | ...  ..  |   . |    | . |. 
slfndenggyqytgkmfinnrradvs....gdpkeytievlpegnsdsvicqvhhha..pwkhl.qqppktlpiikmihqflsekqvqn....agvcvvs

DLGLDRSATVVLTSIIIDQIIAGKTPDCDALFKKMRDQRAGVFTM
 .|  |. . . .   |.|.  |  |.   ..|....|| |    
lfgcgracsfigalyainqlnngiepniceimknikqqrpggves

subfamily_PTPN12_pd Subfamily PTPN12 305-445 1e-08 29.4 In-house 148-286 (290) alignment
Range on Protein: 305-445
Range on HMM: 148-286/290.0
NKGWMN-KYTVEVVA-EGCSEATFAKVYNCTTWPWKKYPDDEKKVLALVRAPYKDTStslianlEKLAPIVVMCDLGLDRSATVVLTSIIIDQIIAGKTP
.. ...  ...  .. |  .|    . .. | || .  |  .|..|.|...  .  .       .. ||.|| |  |  |  |..   .. ... |.|.|
eekavdddflirtLkveaqkesrkvyqfhYtaWPDhgvPssaksllelielvrelqe.......sedaPlvvhCsaGvGrtGtiiaidyvrellkaekip

DCDALF---KKMRDQRAGVFTMSIFYTYAIRAALFYMKIKLQTMND
..  .|    ..| ||| .      |..  .| . ... .|.....
eeldvfdlvlelrkqraalvqtkeqyelvykavaelvqkeleiiee

subfamily_Cele-PTP-6_pd Subfamily Cele-PTP-6 332-436 1.6e-08 28.9 In-house 183-277 (307) alignment
Range on Protein: 332-436
Range on HMM: 183-277/307.0
CTTWPWKKYPDDEKKVLALVRAPYKDTstslianleklAPIVVMCDLGLDRSATVVLTSIIIDQIIAGKT-PDCDALFKKMRDQRAGVFTMSIFYTYAIR
 . || .  |. .   . |. |   ||            |.|| |  |. || |.|  |.. |..|||.   | . | ...|.||       . | |  |
wenwpdrgvpqinltainlleavrydt...........npvvvhcsaGvGrsGtivaislvqdkmiaGinckdmkklveelrsqrhyaiqteaqylylhr

AALFYM
  | |.
vlleyf

subfamily_PTPRG_pd Subfamily PTPRG 321-432 1.9e-08 28.0 In-house 179-283 (563) alignment
Range on Protein: 321-432
Range on HMM: 179-283/563.0
CSEATFAKVYNCTTWPWKKYPDDEKKVLALVRAPykdtstsLIANLEKLAPIVVMCDLGLDRSATVVLTSIIIDQIIAGKTPDCDALFKKMRDQRAGVFT
| .    . |..|.|| .  |. .  ||  |.           || ..  |||| |. |  |. | .  . .. || . .. .   . |..| ||  ...
cdteklvrqyhytkWPdhgvPehslpvLifvkks.......saankaeaGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvq

MSIFYTYAIRAA
    |..   | 
teEqYiflhdal

subfamily_Nvec-PTP-2_pd Subfamily Nvec-PTP-2 313-436 2e-08 28.7 In-house 125-242 (250) alignment
Range on Protein: 313-436
Range on HMM: 125-242/250.0
TVEVVAEGCSEATFAKVYNCTTWPWKKYPDDEKKVLALVRAPYKDTSTSlianleKLAPIVVMCDLGLDRSATVVLTSIIIDQIIAGKTPDCDALFKKMR
.. .  .  ..    . .. ..|| |  |.  . ||.|..   .    .      . ||..| |  |  || . .  . .....   |. |   . |..|
klklskakkaderivrqlhfvvWPdkgvPevatavLellkkvqasqqqa......gnaPvivqCsaGvgrsGafiaidavlerlkkekvvdvfkvikvlr

DQRAGVFTMSIFYTYAIRAALFYM
 .| .. .    | .  ...| ..
kdrphavesleqyvfvyeiilkal

subfamily_Cele-PTP-19_pd Subfamily Cele-PTP-19 170-215 4e-08 27.3 In-house 77-122 (301) alignment
Range on Protein: 170-215
Range on HMM: 77-122/301.0
YINASHIKFDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVTIF
 | |  |. .   . ||.|| ||..|  ||| |.   .| .|| . 
PihanwiptsGhphrfiatqgPlkntsedfwamlvqydvekivmlg

0051082 (Phosphotyrosine protein) phosphatases II 167-427 4.7e-08 28.3 In-house 2-144 (151) alignment
Range on Protein: 167-427
Range on HMM: 2-144/151.0
PDTYINASHIKFDnsqkeFIVTQYPLPdtvrDFWRMVSIMKVTQIVTIFEPQTDEAIEEF-R--Nptltlaapaptstmttiggfpvpigqiahnrdqiq
 ..|||.| .        ......||.    ||....  .... ||.. ...  .   |. .  .                                   
lsdyinfsyvtgg.....lyrsggpla....dflellkelgiktivnlrseeergycpeylpelg...................................

gqsircesnvhrssffpletdhymnlkgwlintrrvtvdhrnkgwmnkytvevvaegcseatfAKVYNCTTWPWKKY--PDDEKKVLALVRAPYKdtsts
                                                                .|...  . |. .  |.  . ||.....  .     
...............................................................ievlhipildwpdpglplsfdavleflellld.....

lianlEKLAPIVVMCDLGLDRSATVVLTSIIIDQiiagktPDCDALFKKMRDQRAGVFTMSIFYTY
      |  |..| |  |..|..|.|.  ... .       . .. .. .| .| ||.. .  . .
.....kkngpvlvHCsaGkgRTGtlvalylmllg......vsleealeeyrlkrpgvvqpnqqflf

subfamily_Choan-PTP-4_pd Subfamily Choan-PTP-4 361-433 5.8e-08 26.9 In-house 220-292 (297) alignment
Range on Protein: 361-433
Range on HMM: 220-292/297.0
SLIANLEKLAPIVVMCDLGLDRSATVVLTSIIIDQIIAGKTPDCDALFKKMRDQRAGVFTMSIFYTYAIRAAL
|| |.  . |...| |  |. ||  |||. .|....  .. ||  |. ...|.||| .      ...   |.|
slraemprnayllvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqtleqfellydavl

subfamily_Cele-PTP-18_pd Subfamily Cele-PTP-18 136-213 8.1e-08 26.3 In-house 49-118 (305) alignment
Range on Protein: 136-213
Range on HMM: 49-118/305.0
LSKNRSKNHKLNDNTRVILSPENtensrtdpPDTYINASHIKFDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVT
  ||| |.    || || | .          |  || | ..      | || || || .|  ||| |    || .|  
agknrykdvgcldnnrvklegpw........pheyihanyvstptnpkrfictqaplektcadfwymclqdkveaifm

subfamily_Cele-PTP-8_pd Subfamily Cele-PTP-8 132-214 8.3e-08 26.6 In-house 40-113 (288) alignment
Range on Protein: 132-214
Range on HMM: 40-113/288.0
WEKSLSKNRSKNHKLNDNTRVILSpentensrtDPPDTYINASHIKFDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVTI
. .. ...| .|    | ||| ||         | || ||.|  .   . .. .| .| ||  |.  .|.|.    |  || .
fianptrdryenlprcditrvkls.........ddpdfyiaanvvssakykrrlicaqaPlngtieelWkmllesdveyivml

subfamily_Cele-PTP-1_pd Subfamily Cele-PTP-1 358-446 8.7e-08 26.6 In-house 179-270 (290) alignment
Range on Protein: 358-446
Range on HMM: 179-270/290.0
TSTSLIANLE-KLAPIVVMCDLGLDRSATVVLTSIIIDQII-AGKTPDCDALFKKMRDQRAGVFTMSIFYTYAIRAALFYMK-IKLQTMNDA
| .||| ... . .|..| |  |. |||..    .    |.   .     .. |..| ||| ..|  . ..... ....... .. |.....
tllsliqkvkasktpvivHcvdGiSrsAalaaiilgyQkiaetsgsvkledvlkalrkqralaitsalelafvdagivllaievldqfaeee

subfamily_PTPN23_pd Subfamily PTPN23 277-437 1.1e-07 26.0 In-house 127-281 (288) alignment
Range on Protein: 277-437
Range on HMM: 127-281/288.0
SFFPLETDHYMNLKGwlintRRVTV-DHRNKGWMNKYTVEVVAEGCSEATFAKVYNCTTWPWKKYPDDEKKVLALVRAPYK---DTSTSLIAnleklaPI
...| .... .. .       .||. ..|. . . ......  .. ..    .  . |.||    |.  ...|... .  .    .   . .      |.
rYwPedkgetvkfgd.....lsvtlksvretethvervlkletldadavksvshlqltsWpelGvPasPetllqfldevesayeavqrkskt......Pl

VVMCDLGLDRSATVVLTSIIIDQIIAGK-TPDCDALFKKMRDQRAGVFTMSIFYTYAIRAALFYMK
|| |  | .|. .. |   .. .. .|.  .|   .....| ||  .   .  .  .  | | . .
vvhCsaGvgRtgvfalvyaavrelekgnglldiiqvvsrlreqRrfmvqekeqlkfsyeavleaar

subfamily_Anemone-PTP-1_pd Subfamily Anemone-PTP-1 137-212 1.6e-07 25.8 In-house 10-81 (239) alignment
Range on Protein: 137-212
Range on HMM: 10-81/239.0
SKNRSKNHKLNDNTRVILspentENSRTDPPDTYINASHIK-FDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIV
.|||  |    | .||.|     |.   ||   |||||... .| | | .| ||  .  .  |||||.   .   ||
aknryanivtydhsrvvl.....eklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcviv

subfamily_Nvec-PTP-1_pd Subfamily Nvec-PTP-1 137-212 1.6e-07 25.7 In-house 9-80 (239) alignment
Range on Protein: 137-212
Range on HMM: 9-80/239.0
SKNRSKNHKLNDNTRVILspentENSRTDPPDTYINASHIK-FDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIV
.|||  |    | .||.|     |.   ||   |||||... .| | | .| ||  .  .  |||||.   .   ||
aknryanivtydhsrvvl.....eklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcviv

subfamily_Cele-PTP-8_pd Subfamily Cele-PTP-8 364-439 1.8e-07 25.5 In-house 201-274 (288) alignment
Range on Protein: 364-439
Range on HMM: 201-274/288.0
ANLEKlaPIVVMCDLGLDRSATVVLTSIIIDQIIAGKTPDCDALFKKMRDQRAGVFTMSIFYTYAIRAALFYMKIK
 .|.|  ||||..  |  |..|..|. |.....          |..|.|..|    .    | |. |  | .. .|
kslqk..PivvhssaGvGrtgtlililialeslrlddflgirsllaklreerfkaiqtemqylyvhrcvleelllk

subfamily_PTPRB_pd Subfamily PTPRB 301-427 2.2e-07 25.2 In-house 154-276 (293) alignment
Range on Protein: 301-427
Range on HMM: 154-276/293.0
VDHRNKGWMNKYTV-EVVAEGCSEATFAKVYNCTTWPWKKYPDDEKKVLALVRAPYkdtstSLIANLEKLAPIVVMCDLGLDRSATVVLTSIIIDQIIAG
|.  ..  ...... |.  |  .| .  . |. |.||    |.. |..|..||.       . | . .. .|||| |  |. |. | .    ....|   
vtlvaeeeledwvirelkiekekeerkvrqyhftsWpdhgvPektktlldfvrtvr.....eaiektaskrPivvhCsaGvGRtGtfialdrllqaieee

KTPDCDALFKKMRDQRAGVFTMSIFYTY
 . |  ..  ..| .|. .      | .
dyvdifgivaelReeRnllvqtekqYif

subfamily_PTPN14_pd Subfamily PTPN14 333-436 2.4e-07 25.1 In-house 191-296 (300) alignment
Range on Protein: 333-436
Range on HMM: 191-296/300.0
TTWPWKKYPDDEKKVLALVRA--PYKDTSTSLIANLEKLAPIVVMCDLGLDRSATVVLTSIIIDQIIAGKTPDCDALFKKMRDQRAGVFTMSIFYTYAIR
| || .. |.| |. |  ..     .  ..| . . |.  |..| |  |  |.  ..|. ..|  .  ... | .  ....| ||  .      |..  .
tDWpdhgvPeDvkgflsyLeevqsvrrktnseveskeskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLreqrmllvqtlaqYkfvYk

AALFYM
. . |.
vlikyl

subfamily_Choan-PTP-1_pd Subfamily Choan-PTP-1 306-439 2.6e-07 25.0 In-house 152-279 (281) alignment
Range on Protein: 306-439
Range on HMM: 152-279/281.0
KGWMNKYTVEVVAEGCSEATFAKVyNCTTWPWKKYPDDEKKVLALVRAPYKDTSTSLIanleklAPIVVMCDLGLDRSATVVLTSIIIDQIIAG-KTPDC
|  . . .... .|.. . . ... . |.|| .  |.. |..|   .. .| |...        ||.|. |  |  |. | .    ..... |  .. | 
katyierkfkleresgetreveql.aytaWPdhGvPattkellefrkevlkltekktk......aplvihCsaGvGrtGtyialDrlvkaveaeleeldv

DALFKKMRDQRAGVFTMSIFYTYAIRAALFYMKIK
.|. ...| .|  .    . |..  .| | ... .
kavvaelrkernlmvqtvvqyefvykavldaldke

subfamily_PTPN3_pd Subfamily PTPN3 332-429 5.7e-07 23.7 In-house 178-268 (280) alignment
Range on Protein: 332-429
Range on HMM: 178-268/280.0
CTTWPWKKYPDDEKKVLALVRAPYKDTstslianLEKLAPIVVMCDLGLDRSATVVLTSIIIDQIIAGKTPDCDALFKKMRDQRAGVFTMSIFYTYAI
 . || .. |||....| .|.   |           |  |.|| |  |..|.  ..|  . .  | | .     .. ..|||||| .   .  |..  
ylaWpdhgvPddsadflefvervrklr.......sgkeePvvvhCsaGigrtGvlilletalalieaaepvypldivrtmrdqramlvqtasqykfvC

subfamily_Sponge-PTP-4_pd Subfamily Sponge-PTP-4 167-209 5.9e-07 23.9 In-house 12-54 (130) alignment
Range on Protein: 167-209
Range on HMM: 12-54/130.0
PDTYINASHIKFDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVT
 .|||||| .   .  .|.. || || ||  |||.|.    | 
gntyinasfvGllgrtaeylltqhpladtsmdfwkmmleryvn

subfamily_PTPRK_pd Subfamily PTPRK 273-432 5.9e-07 23.6 In-house 126-273 (314) alignment
Range on Protein: 273-432
Range on HMM: 126-273/314.0
VHRSSFFPLETDHYMNLKGWLINTrrvtvDHRNKGWMNKYTVEVVAEGCSEATFAKVYNCTTWPWKKYPDDEKKVLALVRAPYKDTSTslianleKLAPI
|. . ..| .|..| ..|  |..|     .  ..  .  ..|| .| | .|    . .. ..||  . |  .. .|.|||   | .         .  .|
vkClkyWPedtevygdikvelvet.....ellaelvvrifrveklargqeeirevrqfqflgWpdhdvPvsatgllklvrrvkksqee.......eaGri

VVMCDLGLDRSATVVLTSIIIDQIIAGKTPDCDALFKKMRDQRAGVFTMSIFYTYAIRAA
|| |  |  |. | .  .|..| |   .. |     |..|...  .      |..   ..
vvhCsaGaGrtGtfiaidivldmieregvvdvfnavktlrsrkvnmveteeqykfiydvi

subfamily_PTPN9_pd Subfamily PTPN9 296-436 7.7e-07 23.4 In-house 146-290 (297) alignment
Range on Protein: 296-436
Range on HMM: 146-290/297.0
TRRVTVDHRNKGWMNKYTVEVVAEGcsEATFAKVYNCTTWPWKKYPDDEKKVLALVRAPYKDTST--SLIANL----EKLAPIVVMCDLGLDRSATVVLT
 ..| |.....  ....... | ..  |      .  ..||    |.. ...| ....  .  ..  . ...      .  |||| |  |. |. | .  
vsnveveeeedykvrvleiknvkte..esrkvthfqflsWPdyGvPssaaslldvlekvrekqalavkelgdewkghpsgPPivvhcsaGiGrtGtfitl

SIIIDQIIAGKTPDCDALFKKMRDQRAGVFTMSIFYTYAIRAALFYM
 | ....    | |     |..| |||    .   |..   | | | 
diclsrleevgtvdvvetvkllrtqrafsiqtpeqyefcylavleya

subfamily_Sponge-PTP8_pd Subfamily Sponge-PTP8 319-426 7.7e-07 23.5 In-house 172-273 (305) alignment
Range on Protein: 319-426
Range on HMM: 172-273/305.0
EGCSEATFAKVYNCTTWPWKKYPDDEKKVLALVRAPYKDTSTSlianleKLAPIVVMCDLGLDRSATVVLTSIIIDQIIAGKTPDCDALFKKMRDQRAGV
.. .|      |. |.|| .  |.    .| |..   || . .      |  |..| |  |. |. . .  .| .... . .. |   . |..| .| ..
dedkesrtvlqyqltdWPdhGvpqfatsllslikrvqkdqkkd......kgvpllVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkm

FTMSIFYT
 .    |.
vqtldqYv

subfamily_Cele-PTP-13_pd Subfamily Cele-PTP-13 135-214 8.2e-07 22.9 In-house 37-112 (281) alignment
Range on Protein: 135-214
Range on HMM: 37-112/281.0
SLSKNRSKNHKLNDNTRVILSPENTENSRTDppdtYINASHIKFDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVTI
   |||  |    | .|| |  .  ..  ||    || | .|.    .. .|.|| |  .|  |||||.   . | || .
nnkknrylnipcldisrvqlkvkmpnknstd....yihanyirspflkrgyiltqgpkketradfwrmiwqenttaivml

subfamily_eak_pd Subfamily eak 166-224 8.2e-07 22.7 In-house 76-133 (332) alignment
Range on Protein: 166-224
Range on HMM: 76-133/332.0
PPDTYINASHIKFDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVTIFEpQTDEAIE
 .. ||||| ..| .  ...|.|  .  | |  ||.||   |   || . | . .. .|
nrlGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlle.dvelkle

subfamily_CG42327_pd Subfamily CG42327 161-217 8.7e-07 22.9 In-house 49-106 (319) alignment
Range on Protein: 161-217
Range on HMM: 49-106/319.0
NSRTDPPDTYINASHIK-FDNSQKEFIVTQYPLPDTVRDFWRMVSIMKVTQIVTIFEP
.   |. | |..||... .|...  .| .| .| |.  ||||.|   .   ||.. ..
rigdddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdl

0048076 (Phosphotyrosine protein) phosphatases II 326-432 1e-06 24.0 In-house 46-139 (145) alignment
Range on Protein: 326-432
Range on HMM: 46-139/145.0
FAKVYNCTTWPWKKYPDDEKKVLALVRAPYKDTSTslianleKlAPIVVMCDLGLDRSATVVLTSIIIDqiiagKTPDCDALFKKMRDQRAGVFTMSIFY
.   | .. ||    ||. . .|.....  .  .        .  |..| |  |..|..|.|.  ...      .  . .  ....| || |...   ..
lgiqylylpwpDhgvpdllellleflefieealke.......g.gpvlVHCsaGvgRtgtlvaaylmll.....lgvsleealelvrsqrpgavpnpgql

TYAIRAA
 . ... 
rflyefe

subfamily_Anemone-PTP-1_pd Subfamily Anemone-PTP-1 277-428 1.1e-06 23.0 In-house 96-233 (239) alignment
Range on Protein: 277-428
Range on HMM: 96-233/239.0
SFFPLETDHYMNLKGWLINTRrVTVDHRNKgwmnKYTveVVAEGCSEATFAKVYNCTTWPWKKYPDDEKKVLALVRAPYKDtstSlianLEKLAPIVVMC
 ..|  | .| ||.  | .|  |  |.  .     .   .   | .|  .   |  | || |  |.    || | |   ||   |    |    | |. |
qywpdstskycnlrvtlrkte.vfadyiir....tfv..msqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitkd...s....lpgarpwvihc

DLGLDRSATVVLTSIIIDQIIAGKTPDCDALFKKMRDQRAGVFTMSIFYTYA
  |. |. ....   .. |    || |     | .|..|  .   |  | . 
sagvgrtgaflvidamlrqakkqktvdifnyvkairedrphmvqtseqyvfi

subfamily_Nvec-PTP-1_pd Subfamily Nvec-PTP-1 277-428 1.1e-06 23.0 In-house 95-232 (239) alignment
Range on Protein: 277-428
Range on HMM: 95-232/239.0
SFFPLETDHYMNLKGWLINTRrVTVDHRNKgwmnKYTveVVAEGCSEATFAKVYNCTTWPWKKYPDDEKKVLALVRAPYKDtstSlianLEKLAPIVVMC
 ..|  | .| ||.  | .|  |  |.  .     .   .   | .|  .   |  | || |  |.    || | |   ||   |    |    | |. |
qywpdstskycnlrvtlrkte.vfadyiir....tfv..msqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitkd...s....lpgarpwvihc

DLGLDRSATVVLTSIIIDQIIAGKTPDCDALFKKMRDQRAGVFTMSIFYTYA
  |. |. ....   .. |    || |     | .|..|  .   |  | . 
sagvgrtgaflvidamlrqakkqktvdifnyvkairedrphmvqtseqyvfi

subfamily_Sponge-PTP6_pd Subfamily Sponge-PTP6 330-431 1.3e-06 22.2 In-house 179-274 (439) alignment
Range on Protein: 330-431
Range on HMM: 179-274/439.0
YNCTTWPWKKYPDDEKKVLALVRAPYKdtstslIANLEKLAPIVVMCDLGLDRSATVVLTSIIIDQIIAGKTPDCDALFKKMRDQRAGVFTMSIFYTYAI
.  ..|| |. | .   || ..||           . |.  |.|| |  |. |. |..   | ..|. . .  | . . | .|.||  .      | .  
fhyiawpdknvpaqashvldflrains......andkeeygpvvvhcsagvGrtGtiialdialeqlklenkvdikgivkvlrkqrkqmvqalcqyvfiy

RA
 |
na

subfamily_Anemone-PTP-5_pd Subfamily Anemone-PTP-5 327-436 2.1e-06 22.0 In-house 180-283 (319) alignment
Range on Protein: 327-436
Range on HMM: 180-283/319.0
AKVYNCTTWPWKKYPDDEKKVLALVRAPYKDTSTslianlEKLAPIVVMCDLGLDRSATVVLTSIIIDQIIAGKTPDCDALFKKMRDQRAGVFTMSIFYT
 | .  | || .. |.. . .|.|..   | ..       ..  |||| |  |  |  | .  .......    . |     ...| ||  .      |.
vkhfqyteWpdhdvPekatslldllkrirksrek......tqsgPivvhCsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeqYk

YAIRAALFYM
.   | | ..
fiyealleav

subfamily_Urchin-PTP-7_pd Subfamily Urchin-PTP-7 298-428 2.4e-06 21.7 In-house 147-271 (315) alignment
Range on Protein: 298-428
Range on HMM: 147-271/315.0
RVTVDHRNKGWMNKYTVEVVaEGCSEATFAKVY--NCTTWPWKKYPDDEKKVLALVRAPYKDTSTSLianleklAPIVVMCDLGLDRSATVVLTSIIIDQ
..|| ....   ..|||  .    ..    .|.  . |.||  . |     .. |.|   .   .|        ..||| |. |  |. | .  . ..||
kitvtrkseevnteytvrtl.svvfgdnirevvqlhytswpdmgvpkytiplmnlirtvkqhhtnsv.......gaivvhcsaGvGrtGtfitldavldq

IIAGKTPDCDALFKKMRDQRAGVFTMSIFYTYA
. | .  |   . ...|..| ..  .   | . 
aeaenaidvynfitgvrqnrikmvqvaeqyqfi

subfamily_PTPRA_pd Subfamily PTPRA 312-436 2.7e-06 21.5 In-house 176-295 (330) alignment
Range on Protein: 312-436
Range on HMM: 176-295/330.0
YTVEVVAEGCSE--ATFAKVYNCTTWPWKKYPDDEKKVLALVRAPYKdtstsliANLEKLAPIVVMCDLGLDRSATVVLTSIIIDQIIAGKTPDCDALFK
. |. ..... |  .   . .  |.||    | . . .| |...  |        |  .  |||| |  |  |. | .  . ..... | .  |     |
flvqqlpdatrekksrlvrqfhftswPdvGvPfepiGmlkllkkvkk.......lnqqsagpivvhcsaGvGrtGtfivldavlervkaerkvdvfefvk

KMRDQRAGVFTMSIFYTYAIRAALFYM
..| ||. .      |..  .. | | 
rlrlqrpqmvqtdeqyefiykvlleyy

subfamily_Cele-PTP-9_pd Subfamily Cele-PTP-9 271-436 3.4e-06 21.3 In-house 66-221 (255) alignment
Range on Protein: 271-436
Range on HMM: 66-221/255.0
SNVHRSSFFPLETDHYMNLKGWLINTRRvtvdHRNKGWMNKYTVEVVAEGCSEATFAKVYNCTTWPWKKYPDDEKKVLALVRAPYKdtSTslianlekla
. .. ||.|||| |  . |.   . | .      ..  .   ..        ..   | |. . |. |. |.. . .| ....  .  |           
gvekcssyfplekdeklkladvnvtttk....ssadvvlrtleitstlgekkkthtvkhysykGWieknaPelareilnilkvvrd..sk..........

PIVVMCDLGLDRSATVVLTSIIIDQ----IIAGKTPDCD--ALFKKMRDQRAGVFTMSIFYTYAIRAALFYM
..||.|. |  |||. ||. ..  .    .   .| . |   | ...| .|..     .  ...|   | ..
svvvhCstGiGrsaafvlaelvyqkmirsldttetveldylslleelrskrkraihtPlqlafsilmvldlv

subfamily_Cele-PTP-20_pd Subfamily Cele-PTP-20 278-433 4.8e-06 20.4 In-house 139-280 (290) alignment
Range on Protein: 278-433
Range on HMM: 139-280/290.0
FFPLETDHYMNLKGWLINTRRVTvDHRNKGWMNKYTVEVVAEGCSeaTFAKVYNCTTWPWKKYPDDEkkvLALVRAPYKDTSTSlianleklAPIVVMCD
..| .  . . .  . .     . |. ..  ..  .|  . .| .     | ..  .|| |  .  .   |||.|  .    .|         |.|| | 
yypekeGevltfGeitvlcseed.dkdaniikktlsvrdkdsGke..hklkhlkikswpdksvalst...lallrtlrilrkas........Gpvvvhcs

LGLDRSATVVLTSIIIDQIIAGKTPDCDALFKKMRDQRAGVFTMSIFYTYAIRAAL
 |. |. | |   . .. .. ||  |   | . .|. |..   . | |   ... |
aGiGrtGtfvaievglqilldGkeldlldlvralrnsrlnsvqvdiqylalveill

0048179 (Phosphotyrosine protein) phosphatases II 328-427 9.8e-06 20.9 In-house 50-136 (144) alignment
Range on Protein: 328-427
Range on HMM: 50-136/144.0
KVYNCTTWPWKKYPDDEKKVLALVRAPYKDtstslianLEKLAPIVVMCDLGLDRSATVVLTSIIIdqiiAGKtPDCDALFKKMRDQRAGVFTMSIFYTY
  | .. ||    ||. . .|.....  .         ||.  |..| |  |..|..|.|.  ...      .  . .  .. .| .| |...   .. .
iqylhlpwpDhgvpdllellleflefieea........leeggpvlVHCsaGvgRtgtlvaaylmk....klg.lsleealalvrsrrpgavpnpgqlrf