Gene K09H11.7 in Caenorhabditis elegans

Synonym: CELE_C45E5.1, C45E5.1

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HAD
Superfamily HAD
Family NagD
Subfamily PGP
Protein sequence
ID Type Fasta BLAST phosphatome Note
CeleP121_AA protein Get Run
CeleP121_AA_18-314 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_PGP_pd Subfamily PGP 31-315 4.1e-117 381.4 In-house 1-277 (279) alignment 
Range on Protein: 31-315
Range on HMM: 1-277/279.0
TFIFDADGVLWLGESVMPGSPRLIDYLVKHNKQIIVLTNNATKSRAVYAKKLAKLGYNssKMNKNNLVNPAAVVADTLHRAGLDGKrVYLIGEQGLRDEM
|..||.||||||||...||.......| |..|.....|||.||||. ..||..|||..  |.........||..||.|...  ..| ||..||.||..|.
tvlfDcDGVlWlgetaipgaaealnaLkklgKkvlfvtNnstksreellkkfkklgfe..kvkeeeilssaaaiadyLkqkkfekk.vyvlgeeglkeeL

DELGIEYFGHGPEKKQDEADgsGAFMYDIKLEENVGAVVVGYEKHFDYVKMMKASNYLREEGVLFVATNEDETCPGPNpEVVIPDAGPIVAAIKCASGRD
.| |||..|.||||..||.|  ..|....||...|||||||......|.|..||.|||||. |||.|||||...|... |||||.||..||||..||||.
keagiellgtgpeklkdeld..edfveelkldkdvgAVvvgvdeklsyakllkAanyLrepevlflatneDallplkk.evvipgaGslvaaieaasgrk

PLTVGKPCTPAFNYIKRKWNINPSRTMMIGDRTNTDVKFGRDHGMKTLLVLSGCHQIEDIIENQMNErdDMVPDYVAPCLGALVP
||..|||... ......|..|.|.||.|||||..||..||...|..|||||||....||. |....|  ..||||....|..|..
plvlGKPnelllelllekeeidpertlmiGDrlktDilfgkncGlqtLlvlsGvtkledveeikkee..klvPdyyldsladlle
Chronophin_1 31-314 3.5e-65 211.0 In-house 3-256 (261) alignment 
Range on Protein: 31-314
Range on HMM: 3-256/261.0
TFIFDADGVLWLGESVMPGSPRLIDYLVKHNKQIIVLTNNATKSRAVYAKKLAKLGYNSSKmnKNNLVNPAAVVADTLHRAGLdGKRVYLIGEQGLRDEM
....| ||||. ||...|| ..||  | ...|.....|||... |. .|..|..|| .. .  .....  |.  |  |... . . .||..||.|||.|.
lvLlDldGVlikgeeavpgAaeliealkqagkevlfvtNnsrrtreelaarlkrlGldava..aeeifssalaaaallrqqaa.kakvyvlGeeglrkel

DELGIEYFGHGPEkkqdeadgsgafmydikleeNVGAVVVGYEKHFDYVKMMKASNYLREEgVLFVATNEDETCPGPNPevVIPDAGPIVAAIKCASGRD
.| |.   ..  .                    .| ||||||...... |. .|....|.   ||||||.| | | ..   ..| .| ..||.. ||||.
reaGlrlvdeped....................rveaVvvGydeelsfeklaeaialirdg.alfvatnrDptvPleeG..iaPgtGslaaaveaAsgre

PLTVGKPCTPAFNYIKRKWNINPSRTMMIGDRTNTDVKFGRDHGMKTLLVLSGCHQIEDIIENQmnerDDMVPDYVAPCLGALV
|| |||| .  |. . .| ...|..|.|.||| .||...|.. |..|||||.|  . |.. . .    .|..||.|.  .  |.
plvvGKPepvmfeealekigadpeetvmvGDRldTDilagaraglstllvltGvseleeaqayk....kdlrPdavvesiadll
Chronophin_2 31-312 7.5e-62 200.1 In-house 2-275 (282) alignment 
Range on Protein: 31-312
Range on HMM: 2-275/282.0
TFIFDADGVLWLGESVMPGSPRLIDYLVKHNKQIIVLTNNATKSRAVYAKKLAKLGYNSskMNKNNLVNPAAVVADTLHRAGLDGKRVYLIGEQGLRDEM
. .|| |||.| || ...|.| ... |... |... .|||.|..|  |..|.|.||.    ......   |   |  |  .     .|. || .||| |.
nvlfdcdgviwngekavagapevvsrlaragknvlfvtnnstrarenyvlkfarlgfad..vaaeqifssaycsaaylrdvadvrgkvfviggeglrkel

DELGIEYFGHGPEKKqdeadgsgAFMYDIKLEENVGAVVVGYEKHFDYVKMMKASNYLREEGVLFVATNEDETCPGPNPEvVIPDAGPIVAAIKCASGRD
 | |..  ..  |..        | .||. |. .| ||.|||.... ..|. ||. |||.   |..||..|   |  . . ..| .| . ||.. |||| 
reagvpvvedadeqe........asiydcaldpdvravlvgydekltflklakacaylrdadclllatdrdpwhplsdgr.itpgsgsltaaletasgrk

PLTVGKPCTPAFNYIKRKWNINPSRTMMIGDRTNTDVKFGRDHGMKTLLVLSGCHQIEDII---ENQMNERDDMVPDYVAPCLGA
 . .|||    |. |  .....|.|..||||| .||. || . |..|.| |.|  ..|.     ..|. |. |.|||||  ..  
atvigkpsrfmfecissqfsvdparslmigdrletdilfgsncglstvltltgvssleeaqeysdsqlaeqrdlvpdyvvesiad
subfamily_LHPP_pd Subfamily LHPP 32-288 9.2e-28 88.7 In-house 1-224 (227) alignment 
Range on Protein: 32-288
Range on HMM: 1-224/227.0
FIFDADGVLWLGESVMPGSPRLIDYLVKHNKQIIVLTNNATKSRAVYAKKLAKLGYNsskMNKNNLVNPAAVVADTLHRAGLdgkRVYLIGEQGLRDEMD
.. |  |||. .....||.   .. | ...... ..||.  .|..  ...| .||..   ....... ........|..  |   | ||. |.. .....
vllDlsGvlhnedaaipgavealkrLrqagvkvrfvtNttkeskralverLirlgfd...veeeeiftsleaarqllrerkl...rpyllveddveedfe

ELGIEYFghgpekkqdeadgsgafmydikleenvGAVVVGY-EKHFDYVKMMKASNYLRE-EGVLFVATNEDETCPGPNPevVIPDAGPIVAAIKCASGR
..  .                              |||.|  ...|.| .. .| . | | ..   .| |..     ..   .. ..|. |.|.. | | 
didtdkp...........................navviglapesfeyetlnqafrllleakkakliainkgkyykrkdG..lalgpGafvkaleyatgv

DPLTVGKPCTPAFNYIKRKWNINPSRTMMIGDRTNTDVKFGRDHGMKTLLVLSGCHQIE
.   ||||    |.   .. ...|.. .|||| .. ||.   . |....|| .| .. |
kaevvGKPsalffekaleelgvdpeeavmiGDdvedDveGAlkaGlrgvlVktGkfrpe
Hydrolase_6 Haloacid dehalogenase-like hydrolase 32-136 1.1e-27 87.4 Pfam-A 1-101 (101) alignment 
Range on Protein: 32-136
Range on HMM: 1-101/101.0
FIFDADGVLWLGESVMPGSPRLIDYLVKHNKQIIVLTNNATKSRAVYAKKLAKLGYNsskMNKNNLVNPAAVVADTLHRAgLDGKRVYLIGEQGLRDEMD
|.|| ||||| |....||...... | ...|....||||..||.. ||||| |||..   ......| .| ..|. |..    .|.|..|||.|||.|..
flfDvdGvLwrgdkaipgaaealkalraagkpvvllTNnsskseeeyakkleklgvd...vteeqvvtsataaaeylkkr.kadkkvlvigeeglreelk

ELGIE
| |..
eaGfk
Hydrolase haloacid dehalogenase-like hydrolase 29-273 1.2e-16 53.1 Pfam-A 1-214 (215) alignment 
Range on Protein: 29-273
Range on HMM: 1-214/215.0
IDTFIFDADGVLWLGESVM--PGSPRLIDYLVKH---------NKQIIVLTNNATKsravyakklaklgynsskmnKNnlVNPAAVVADTLHRAGLDGKr
|.|..|| .|.|. || ..  .|   ..... ..         .. ... ..| |.                    ..  .   |...     .  ||. 
iktvvfDktGTLtegepsvallgnkaalalaaaletgsehpigkavvaaakanstr....................gg..ltgfatfigrgvsgkvdgi.

vYLigeqGLRDEMDELGIEYFGHGPEKKQDEADGSGAFMYDIkleeNVGAVVVGYEKHFDYVKMMKASNYLREEGV-LFVAT-------NEDETCPGPNP
 .|    | .. | .||....     ...... |  .  . .    .. |. |  .    . ....| ..|.|.|. ....|       . . . .| . 
.vl....gnpewmtalglrviapdlvaaegqskgrtvvvvav....qaralgviafadpvkpeaaeavasLkeaGievvlltgdnpetaeaiakqagied

EVVIPDAGpivaaikcasgrdpltvGKPCTPAFNYIKRKWNINPSRTMMIGDRTnTDVKFGRDH
..|  ..                  |||    |... ....|.|....|.||.  .|.....  
slvfaevv.................gkPepklfvaaieeLqidpgevamvGDgv.nDapalaaA
Hydrolase_like HAD-hyrolase-like 235-306 2.7e-14 44.2 Pfam-A 3-68 (75) alignment 
Range on Protein: 235-306
Range on HMM: 3-68/75.0
GKPCTPAFNYIKRKWNINPSRTMMIGDRTNTDVKFGRDHGMKTLLVLSGCHQIEDIIEnqmnerDDMVPDYV
|||    . .. .. ...||...||||. .||.....  |....|||.| .. ||  .      .   ||||
gKPnpgmydkalevlgappsevvmiGDslatDieaAnnaGirsilVltGvsreedlkl......akakpdyv
HAD_2 Haloacid dehalogenase-like hydrolase 230-280 1.9e-06 19.5 Pfam-A 127-176 (176) alignment 
Range on Protein: 230-280
Range on HMM: 127-176/176.0
DPLTVGKPCTPAFNYIKRKWNINPSRTMMIGDRTnTDVKFGRDHGMKTLLV
|   . ||.  |. .. .. ...| ....|.|.   ||. .|. |..| .|
ddvgapKpdpeayekvlerlgvkpeeilfidDsl.edveaAraaGirtvhv
CECR5_TIGR01456 19-79 3.7e-06 16.5 In-house 29-92 (370) alignment 
Range on Protein: 19-79
Range on HMM: 29-92/370.0
PDTFAKVMKTIdTFIFDADGVLWLGESVMPGSPRLIDYLVKHNKQ----IIVLTNNATKSRAVYA
  ....  |.. .|..| |||| .|.....|..  .  ||... .    ...|||    |    |
kvspessskkf.gfaldiDGvllrGkkpiagaskalrrLvddqGalkiPvllltngGglserara