Synonym: CELE_M05B5.1, M05B5.1
Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
| Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
|---|---|---|---|---|---|---|---|---|---|
| subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 79-420 | 2.9e-221 | 728.0 | In-house | 1-347 (347) | alignment | ||
Range on Protein: 79-420
Range on HMM: 1-347/347.0
LCKYILDMKEASLNTYFDANLANYSPSKCTFNEWEKNVNKNRTKDVKLIDATRVVLTnPEKSKMGPADDVEGYINASHIRFDNASTDYILTQYPLPSTIR
.|||.||.|||||.||||.|||||||||.|..||||...|||.|||||||||||||. |||||...|||||.|||||||.|||||..|||||||||.|.|
fckylldikeaslstyfdenlanyspskftsvewekslsknrskdvklidatrvvls.peksknsraddvetyinashikfdnaskeyiltqyplpdtvr
DFWKMVYVTKVTQVITIFEPIKDEAIEEFANfpAPASPVPPPPTASSKDIGSSP---DQQPREREQIEIKSIRCDNHLHQ-SFFPLSTDHYLNLEGWLIN
||||||.|||||||.|||||||||||||||| |..|.|.|.|||||||||||| ||..|||||||||||||...||. |||||.|||||||.|||||
dfwkmvsvtkvtqvvtifepikdeaieefan..atlslvapaptasskdigsspvpidqiarereqieiksircesnlhrssffpletdhylnlkgwlin
TRAVEVDQRCKNWMNKYTVEVVADGCSEATFAKVYNCTTWPWKSYPDDVKKVLALVRAPVKESSPT----VGKQPPVIVMCDLGLDRSATVVLTSIIIEQ
|||||||||.|||||||||||||.|||||||||||||||||||.||||.|||||||||||||||.. ..|..||.||||||||||||||||||||||
travevdqrnknwmnkytvevvaegcseatfakvyncttwpwkkypddekkvlalvrapvkesstslianleklapvvvmcdlgldrsatvvltsiiieq
VLDGKTPDCDDLFRKMRDQRAGVFTMSIFFTYAIRAALFYLKLKLQCLNE
|||||||||||||.|||||||||||||||.||||||||||||||||.|||
vldgktpdcddlfkkmrdqragvftmsifytyairaalfylklklqtlne
|
|||||||||
| DSPc_SM00195 | 91-412 | 4.4e-72 | 237.9 | In-house | 2-263 (263) | alignment | |||
Range on Protein: 91-412
Range on HMM: 2-263/263.0
LNTYFDANLANYSPSKCTFNEWEKNVNKNRTKDVKLIDATRVVLTNPEKSkmgpadDVEGYINASHIRFDNASTDYILTQYPLPSTIRDFWKMVYVTKVT
|...|. ....||...| .|..||..||| |.....| ||| |...||. . . ||||..|...| . .||.||.|||||..|||.||. .||.
lkeefekleestspketteaekkknksknRyknilpydhtrVklkkeekk......egsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvk
QVITIFEPIKDEAIEEFANFPAPAspvpppptasskdigsspdQQPREREQIEIKSIRCDNHLhqsffplstdhylnlegwlintravevdqrckNWMNK
......|. ... .. ..| . ... . ..|..| ...... .....
iivmlteeeengkekcdrywpees...................ggketfgkisvklvevekkk................................deiil
YTVEVVADGCSEATFAKVYNCTTWPWKSYPDDVKKVLALVRAPVKESSPTvgkQPPVIVMCDLGLDRSATVVLTSIIIEQVLDGKTPDCDDLFRKMRDQR
.|.|. ..|..|......|....||....||. |.||.|.|| |..| . ..|..|.|. |..|..|.|...||.... ..|..|........|.||
rtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkksksts...sgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqR
AGVFTMSIFFTYAIRAALFYLK
.|..... .......|.|.|.|
pgmvqtleqYlfiyeaileyik
|
|||||||||
| PTPc_SM00194 | 91-412 | 4.4e-72 | 237.9 | In-house | 2-263 (263) | alignment | |||
Range on Protein: 91-412
Range on HMM: 2-263/263.0
LNTYFDANLANYSPSKCTFNEWEKNVNKNRTKDVKLIDATRVVLTNPEKSkmgpadDVEGYINASHIRFDNASTDYILTQYPLPSTIRDFWKMVYVTKVT
|...|. ....||...| .|..||..||| |.....| ||| |...||. . . ||||..|...| . .||.||.|||||..|||.||. .||.
lkeefekleestspketteaekkknksknRyknilpydhtrVklkkeekk......egsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvk
QVITIFEPIKDEAIEEFANFPAPAspvpppptasskdigsspdQQPREREQIEIKSIRCDNHLhqsffplstdhylnlegwlintravevdqrckNWMNK
......|. ... .. ..| . ... . ..|..| ...... .....
iivmlteeeengkekcdrywpees...................ggketfgkisvklvevekkk................................deiil
YTVEVVADGCSEATFAKVYNCTTWPWKSYPDDVKKVLALVRAPVKESSPTvgkQPPVIVMCDLGLDRSATVVLTSIIIEQVLDGKTPDCDDLFRKMRDQR
.|.|. ..|..|......|....||....||. |.||.|.|| |..| . ..|..|.|. |..|..|.|...||.... ..|..|........|.||
rtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkksksts...sgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqR
AGVFTMSIFFTYAIRAALFYLK
.|..... .......|.|.|.|
pgmvqtleqYlfiyeaileyik
|
|||||||||
| 0036941 | (Phosphotyrosine protein) phosphatases II | 80-419 | 5.1e-58 | 192.1 | In-house | 4-285 (297) | alignment | ||
Range on Protein: 80-419
Range on HMM: 4-285/297.0
CKYILDMKEASLNTYFDANLANYSPSKCTFNEWEKNVNKNRTKDVKLIDATRVVLtnpekskmgpADDVEGYINASHIRFDNASTDYILTQYPLPSTIRD
.... . | | ..|. | .. . ... ....|..||| ||. | |||.| |. .|||||.. . . . .|.||.|||.|. |
kllekllflalllkefeellpllllgslsvallpenleknRykdilpydhtRVkl..........ddegsdYinAsyvdgydlkrkfIatqgPlpntved
FWKMVYVTKVTQVITIFEPIKDEAIEefanfpapaspvpppptasskdigsspdqqprereqieiksircdnhlHQSFFPLSTDHYLNLEGWLINTRAVE
||.||. .|| .... |.. .. . ....|| ....|. ... .... ||
FWrmvweqnvtvIvmltelvelgrek................................................caqywpleegesltygdftvtllsve
VDqrCKNWMNKYTVEVVADGCSEATFAKVYNCTTWPWKSYPDDVKKVLALVRApVKESSPTVGKQPPVIVMCDLGLDRSATVVLTSIIIEQVL---DGKT
|. .... .|.||. |..| . ... .|.||. . |.... .|..... |.. . ...||.|.| |. ||.|... ....|. ..
vv..llddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfiel.vrkvlkllpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkegg
PDCDDLFRKMRDQRAGVFTMSIFFTYAIRAALFYLKLKLQCLN
.| ....|.|.||.|.... .. . ..| |..|| ||....
vdileavkklReqRpgavqtleqyrflyeallellkkkltkep
|
|||||||||
| 0040438 | (Phosphotyrosine protein) phosphatases II | 81-419 | 4.7e-56 | 185.7 | In-house | 7-284 (317) | alignment | ||
Range on Protein: 81-419
Range on HMM: 7-284/317.0
KYILDMKEASLnTYFD---ANLANYSPSKCTFNEWEKNVNKNRTKDVKLIDATRVVLTNPEKskmgpaDDVEGYINASHIRFDNASTDYILTQYPLPSTI
...||.. . |.. .| ..... ... |...| .||| .|. . |..||.|..... | .|||||.. . | .. .|.||.|||.|.
lalldllksdf.talleefedllslkldtysvaelpenkdknrypdilpydhsRVkLsplgg......dldsdYInAsyvdgpnlkrkfIatqgPlpntv
RDFWKMVYVTKVTQVITIFEPIKDEAIEefanfpapaspvpppptasskdigsspdqqprereqieiksircdnhlHQSFFPLstDHYLNLEGWLINTRA
|||.||. .|| .... |. .. . . ..|| ...|. ... ....
edFwrmvweqgvtvivmLteleelgrek................................................caqYwpl..getltygdftvtlls
VEVdqrcKNWMNKYTVEVVADGCSEATFAKVYNCTTWPWKSYPDDVKKVLALVRAPVKESSptvGKQPPVIVMCDLGLDRSATVVLTSIIIEQVLDGKTP
.|. .. .. .|.||. .|.|| . ... .|.|| . |.. . .|....| . . ... ||.|.| |..|..|... ...||. ....
eee....lagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavreale...dpggpvlVHCsaGvgRtGtfiaaylmleqlekeggv
DCDDLFRKMRDQRAGVFTMSIFFTYAIRAALFYLKLKLQCLN
| .. ....| ||.|.... .. . ..|.|.||| ||.. .
dveeavkelreqRpgavqtpeqyrflydalleylkrkltlep
|
|||||||||
| 0050432 | (Phosphotyrosine protein) phosphatases II | 89-418 | 1.6e-54 | 180.7 | In-house | 42-306 (308) | alignment | ||
Range on Protein: 89-418
Range on HMM: 42-306/308.0
ASLNTYFDANLANYSPSKCTFNEWEKNVNKNRTKDVKLIDATRVVLtnpekskmgpaDDVEGYINASHIRFD--NASTDYILTQYPLPSTIRDFWKMVYV
|...| . |... . .... ....|..||| ||. | .||.| |. .|||||.... . . .|.||.|||.|. |||.||.
glleeefeellsvkplleysvallpenkdkNrykdilpydhsRVkl...........degsdYInAsyvdgyssklprkfIatqgPlpntvedFwrmvwe
TKVTQVITIFEPIKDEAIEefanfpapaspvpppptasskdigsspdqqprereqieiksircdnhlHQSFFPLSTD-HYLNLEGWLINTRAVEVdqrcK
.|. .... ... .. . ..||... ..|. ... .... .|| .
qnvrvIvmLtklvengrek................................................caqYwplelgggsleygkftvtllseev....l
NWMNKYTVEVVADGCSEATFAKVYNCTTWPWKSYPDDVKKVLALVRAPVKESsptvgKQPPVIVMCDLGLDRSATVVLTSIIIEQVLDGKTPDCDDLFRK
... ..|.|.. |..| . ... .|.|| . |.... .|..... | ...|..|.| |. |..|... ...||. ....| ....|
ddytvrtleltnlgdgesrtvthfhytnWpdhgvPpspeilldflelvrksl.....pggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkk
MRDQRAGVFTMSIFFTYAIRAALFYLKLKLQCL
.| ||.|... . . .||.|.||||||..|
lReqRpgmvqtpeqylflyralleylklkltkl
|
|||||||||
| 0047943 | (Phosphotyrosine protein) phosphatases II | 95-411 | 1.3e-51 | 171.1 | In-house | 18-272 (273) | alignment | ||
Range on Protein: 95-411
Range on HMM: 18-272/273.0
FDANLANYSPSKCTFNEWEKNVNKNRTKDVKLIDATRVVLtnpekskmgpA----DdvegYINASHIRFDNASTDYILTQYPLPSTIRDFWKMVYVTKVT
|.. | .. . .... ....| .||| ||. | .||.| | |||||.... | . .|.||.|||.|. |||.||. .|.
felllslkplltysvallpenkdknrykdilpydhsrvkl..........gdggsd....yinAsyvdgynlkrkfiatqgPlpntvedfwrmvweqnvr
QVITIFEPIKDEAIEefanfpapaspvpppptasskdigsspdqqprereqieiksircdnhlHQSFFPLSTDH-YLNLEGWLINTRAVEVdqrcKNWMN
.... |.. .. . . ..||. .. .|. . . .... .|. |...
viVmLtelvelgrek................................................caqYwpleggelsltygkftvtllseet....kddyt
KYTVEVVADGCSEATFAKVYNCTTWPWKSYPDDVKKVLALVRApVKESSPTVGKQPPVIVMCDLGLDRSATVVLTSIIIEQVLDGKTPDCDDLFRKMRDQ
..|.|.. |..| . ... .|.|| . |.... .| .... |.. .. ...||.|.| |. |..|... ....|. ....| .......|.|
vrtleltnlgtgesrtvthfhytgwpdhgvppslesllefiel.vrkalealpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsq
RAGVFTMSIFFTYAIRAALFYL
| |... .. . ..|.|.||
Rpgmvqtpeqyrflyealleyl
|
|||||||||
| 0051299 | (Phosphotyrosine protein) phosphatases II | 90-412 | 4.6e-51 | 169.4 | In-house | 24-287 (288) | alignment | ||
Range on Protein: 90-412
Range on HMM: 24-287/288.0
SLNTYFDANLANYSPSKCTFNEWEKNVNKNRTKDVKLIDATRVVLTNPEKskmgpaDDVEGYINASHIRFDNASTDYILTQYPLPSTIRDFWKMVYVTKV
| |.. |... . .... ...|..||| .|. | .||.|..... .. .|||||.|.. | . .|.||.|||.|. |||.||. .|
glleefeellsllpdltlsaallpenleknRysdilpydhsRVkLsvldg......vegsdYinAsyidgynlkrkfIatqgPlpntvedFWrmvweqnv
TQVITIFEPIKDEAIEefanfpapaspvpppptasskdigsspdqqprereqieiksircdnhlHQSFFPLstDHYLNLEGWLINTRAVEVdqrcKNWMN
. .... ... .. . ..|| ...|... . .... .|| .. .
rvIvmltklvelgrek................................................caqYwpl..ggsltygditvtllseev....lddyt
KYTVEVVAD----GCSEATFAKVYNCTTWPWKSYPDDVKKVLALVRAPVKESSptvGKQPPVIVMCDLGLDRSATVVLTSIIIEQVLDGKTPDCDDLFRK
..|.||. |..| . ... .|.|| ..||... .|...|. | . ...||.|.| |..|..|... ...||.. ....| .....
vrtlevtnldlldgdgesrtvthfhytnwpdhgvpdspellldflrlvrkala...sgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkr
MRDQRAGVFTMSIFFTYAIRAALFYLK
.| || |.... . . ..|.|.|||
lreqRpgmvqtpeqyrfvyealleylk
|
|||||||||
| 0043336 | (Phosphotyrosine protein) phosphatases II | 98-411 | 1.2e-49 | 164.7 | In-house | 28-277 (278) | alignment | ||
Range on Protein: 98-411
Range on HMM: 28-277/278.0
NLANYSPSKCTFNEWEKNVNKNRTKDVKLIDATRVVLTNpekskmGPADDVEGYINASHIRFDNASTDYILTQYPLPSTIRDFWKMVYVTKVTQVITIFE
.| .. . ... ....|..|||.||. . | .||.|.. . | .|||||.. . | ....|.||.|||.|. |||.||. .|| .... |
ellsfkldtysiallpenkdknrykdilpydhsrvklsl......lggdldsdYinAsyvdgynvprkfiatqgPlpetvedFwrmvwelgvttivmLte
PIKDEAIEefanfpapaspvpppptasskdigsspdqqprereqieiksircdnhlHQSFFPlstDHYLNLEGWLINTRAVEVdqrcKNWMNKYTVEVVA
. .. . . ..| ...|. ... .... .|. .... .| ||.
lvelgrvk................................................caqYwp...ggsltygdftvtllkeeh....lddytvrtlevtn
DGCSEATFAKVYNCTTWPWKSYPDDVKKVLALVRAPVKESSptvGKQPPVIVMCDLGLDRSATVVLTSIIIEQVLDGKTPDCDDLFRKMRDQRAGVFTMS
|..| . .| .. || . |.... .| ...| . . .. ||.|.| |..|..|... ...||. .....| .. ....| ||.| ...
lgdgesrtvthyhylgwpdhgvpeslsllldflkavreale...dsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtp
IFFTYAIRAALFYL
.. . ..|.|.||
sqyrflyealleyl
|
|||||||||
| 0046845 | (Phosphotyrosine protein) phosphatases II | 105-419 | 1.6e-49 | 164.2 | In-house | 18-282 (284) | alignment | ||
Range on Protein: 105-419
Range on HMM: 18-282/284.0
SKCTFNEWEKNVNKNRTKDVKLIDATRVVLTNPEKSkmgpaDDVEGYINASHIRFD-----NASTDYILTQYPLPSTIRDFWKMVYVTKVTQVITIFEPI
.... ...|..||| ||. | .||.|...... .. .|||||.... . . .|.||.|||.|. |||.||. .|. .... |..
lslsvallpenlsknRykdilpydhsRVklksldgd.....ledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqnvrvIVmltelv
KDEAIEefanfpapaspvpppptasskdigsspdqqprereqieiksircdnhlHQSFFPLStDHYLNLEGWLINTRAVEVdqrcKNWMNKYTVEVVADG
.. . . ..||. ...|..... .... .|| |... ..|.|.. |
engrek................................................caqYwple.gevltygdftvtllseev....kddytvrtleltnlg
-CSEATFAKVYNCTTWPWKSYPDDVKKVLALVRApVKESSPTVGKQPPVIVMCDLGLDRSATVVLTSIIIEQVLDGK---TPDCDDLFRKMRDQRAGVFT
..| . ... .|.|| . |.... .|...|. |.|. . .....|..|.| |. |..|... ...||. .. ..| ......|.|| | ..
ytgesrtvthfhytswpdhgvppspedlleflrl.vrellenlpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvq
MSIFFTYAIRAALFYLKLKLQCLN
. . . ..|.|.||||||..|.
tleqyrfvyealleylklkltlle
|
|||||||||
| 0045450 | (Phosphotyrosine protein) phosphatases II | 103-411 | 1.8e-48 | 161.2 | In-house | 43-304 (307) | alignment | ||
Range on Protein: 103-411
Range on HMM: 43-304/307.0
SPSKCTFNEWEKNVNKNRTKDVKLIDATRVVLTNPEKSkmgpaDDVEGYINASHI--------RFDNASTDYILTQYPLPSTIRDFWKMVYVTKVTQVIT
. .... ....| .||| ||. . | |||.|.....| .. .|||||.. . . .. .|.||.|||.|. |||.|.. .|| ...
llgeysiallpenkdknrykdilpydhtRVklssldgs.....ledsdYiNAsyvrvpllllldgydlkrkfIatqgPlpetvedFwrmlweqgvtvivm
IFEPIKdeaieefanfpapaspvpppptasskdigsspdqqprereqieiksirCDNHLHQSFFPLStDHYLNLEGWLINTRAVEVdqrcKNWMNKYTVE
. |.. ... ..|.. ...|. . . .... .|. .. . .|.|
ltelve................................................lgrekcaqywPde.geeltygnftvtllseeh....ldgytvrtle
VVAD-GCSEATFAKVYNCTTWPWKSYPDDVKKVLALVRAPVKeSSPTVGKQPPVIVMCDLGLDRSATVVLTSIIIEQVLDGKT---PDCDDLFRKMRDQR
| |..| . ... .|.|| . |.... .|..... | . .|. ||.|.| |..|..|... ....|. ...| .| .. ....|.||
vtdldgtgesrtvthfhytgwpdhgvppsfeelldfieevrk.aleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqR
AGVFTMSIFFTYAIRAALFYL
|... .. . ..|.|..|
pgavqnpeqyrflyeallell
|
|||||||||
| 0039614 | (Phosphotyrosine protein) phosphatases II | 98-416 | 5.9e-48 | 159.2 | In-house | 40-294 (297) | alignment | ||
Range on Protein: 98-416
Range on HMM: 40-294/297.0
NLANYSPSkCTFNEWEKNVNKNRTKDVKLIDATRVVLTNPEkskmgPADDVEGYINASHIRFDNA-STDYILTQYPLPSTIRDFWKMVYVTKVTQVITIF
.| .. |. ... ....|..||| ||. | .||.|. .. | |||||.. . . . ..|.||.|||.|. |||.||. .|| ....
ellslkpd.ysiallpenkdknrykdilpydhsrvklkped.....gvdldsdYinAsyvdgydlltrkfIatqgPlpetvedFwrmvweqgvtvivmLt
EPIKDEaieefanfpapaspvpppptasskdigsspdqqprereqieiksircdNhLHQSFFPLSTDhylNLEGWLINTRAVEVdqrcKNWMNKYTVEVV
... .. . ....| ... . ... .... ||. .. .. .| ||.
klvelg................................................r.kcaqywpeegg...tygdftvtllkveh....ldgytvrtlevt
ADGCSeaTFAKVYNCTTWPWKSYPDDVKKVLALVRAPVKESSPTvGKQPPVIVMCDLGLDRSATVVLTSIIIEQVLDGKTPDCDDLFRKMRDQRAGVFTM
.|.| . ... .| ||. . |.... .| .... . . . .|. ||.|.| |..|..|... ...||. ....| .. ....| || |....
nnges..rtvthfqytgwpdhgvppslellleflelvrealael.pkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqt
SIFFTYAIRAALFYLKLKLQ
.. . ..|.|..|| ||.
psqyrflydallellkrklt
|
|||||||||
| 0045098 | (Phosphotyrosine protein) phosphatases II | 93-413 | 6.8e-45 | 149.0 | In-house | 11-274 (278) | alignment | ||
Range on Protein: 93-413
Range on HMM: 11-274/278.0
TYFDANLANYSPSKCTFNEWEKNVNKNRTKDVKLIDATRVVltnpekskmgpaddveGYINASHIRFDnaSTDYILTQYPLPSTIRDFWKMVYVTKVTQV
..|. .|. ..||..|.. ...|..||| ||. .| .||. .|||||.|.. .. .|.||.|||||. |||.|.. ..| .
lefefllllgipseitpalylgnldknRykdilpydhsrVk................dYINAsyidgy..pkkfIatqgPlpstvadfwrmlwelgitvi
ITIFEPIKDEaieefanfpapaspvpppptasskdigsspdqqprereqieiksircdN-HLHQSFFPlstDHYLNLEGWLINTRAVEVDqrCKNWMNKY
... | . .. . . .| . . ...|. ... ... .|| . .. ..
vmltelvelg................................................rekcaqywpe...ggsltygdftvtllseevl..ddytlrtl
TVEVV--ADGCSEATFAKVYNCTTWPWKSYPDDV--KKVLALVRAPVKESS----------PTVGKQPPVIVMCDLGLDRSATVVLTSIIIEQVldGKTP
.|. . . | . .......|| . |.. | .| |.. . . . ... ||.| | |..|..|.|. ...|.. ...
lvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvlVHCsaGvgRtGtlvaaylmlell..eggv
DCDDLFRKMRDQRAG-VFTMSIFFTYAIRAALFYLKL
| .. ....| || | .... .. . ....| .|.
dlleavkelrsqRpglavqnleqyrflyefllelllr
|
|||||||||
| 0040439 | (Phosphotyrosine protein) phosphatases II | 106-411 | 1.6e-44 | 147.8 | In-house | 2-246 (249) | alignment | ||
Range on Protein: 106-411
Range on HMM: 2-246/249.0
KCTFNEWEKNVNKNRTKDVKLIDATRVVLTNPEKskmgpaDDVEGYINASHIRFDNASTDYILTQYPLPSTIRDFWKMVYVTKVTQVITIFEPIKDEAIE
.... ....|..||| .|. | .||.|. .. .|||||.| . . ....|.||.|||.|. |||.|.. ..| .... .. . .
eysvallpenkdknrypdilpydhsrvklsilpg......lflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrek
efanfpapaspvpppptasskdigsspdqqprereqieiksircdnhlHQSFFPLstDHYLNLEGWLINTRAVEVdqrcKNWMNKYTVEVVADGCSEATF
. ..|| ...|. ... .... ||| |... .|.|.. ...|
................................................caqywpl..ggsleygdftvtllsvev....kddytvrtleltnlydgesrt
AKVYNCTTWPWKSYPDDVKKVLALVRAPVKESSPTvGKQPPVIVMCDLGLDRSATVVLTSIIIEQVLDGKTPDCDDLFRKMRDQRAGVFTMSIFFTYAIR
.....| || . |.... .|....| | . . .|. ||.|.| |..|..|... ...||. .. | .. ....|.|| |.... .. . ..
vlhiqytdwpdhgvppsfedlldfieavrkaleel.pkggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdleeavkllrsqRpgavqnpeqyrflye
AALFYL
|.|..|
allell
|
|||||||||
| 0042113 | (Phosphotyrosine protein) phosphatases II | 107-412 | 3e-43 | 143.4 | In-house | 1-244 (245) | alignment | ||
Range on Protein: 107-412
Range on HMM: 1-244/245.0
CTFNEWEKNVNKNRTKDVKLIDATRVVLTNPEKSKMGPaddvegYINASHIRFDNASTDYILTQYPLPSTIRDFWKMVYVTKVTQVITIFEPIKDEAIEe
... ....|..||| .|. . | |||.|.... . . |||||.. ... . .|.||.|||.|. |||.|.. ..| .... |. .. .
ysvallpenkdknrysdilpydhtrvklspdggdldsd......yinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvk.
fanfpapaspvpppptasskdigsspdqqprereqieiksircdnhlHQSFFPLstDHYLNLEGWLINTRAVEVdqrcKNWMNKYTVEVVADGCSEATFA
. ..|| ...|. ... .... .|. .... .|.||. .|..| .
...............................................caqywpl..gesltygdftvtllseeh....lddytvrtlevtnlgddesrev
KVYNCTTWPWKSYPDDVKKVLALVRAPVKESSPtvGKQPPVIVMCDLGLDRSATVVLTSIIIEQVLDGKTPDCDDLFRKMRDQRAGVFTMSIFFTYAIRA
.| .. || . ||... .| .... | . ... ||.|.| |..|..|... ...||. .. . .. ....|.|| |.... .. . ..|
ihyhylpwpdhgvpdllellldflefvrkalae..dsngpvlVHCsaGvgRtGtfiaaylmleqlekelgvsleeavkelrsqRpgavqtpsqyrflyea
ALFYLK
.|..||
llellk
|
|||||||||
| 0037934 | (Phosphotyrosine protein) phosphatases II | 107-411 | 1e-29 | 99.3 | In-house | 2-242 (243) | alignment | ||
Range on Protein: 107-411
Range on HMM: 2-242/243.0
CTFNEWEKNVNKNRTKDVKLIDATRVVLtnpekskmgpaDDvEGYINASHIRFDNastDYILTQYPLPSTIRD----FWKMVYVTKVTQVITIFEPIKDE
... .. |..||| .|. . | .||.| .. ..||||..|. . .|.||.|||.|. | ||.|.. ..| .... |.. .
fsiallpenlsknrysdilpydhsrvkl...........eg.sdyinanliyvtp...rliatqgPlpetveddlasfwrmlwelgitvivmltelvElg
AIeefanfpapaspvpppptasskdigsspdqqprereqieiksircdnhLHQSFFPlstDHYlNLEGWLINTRAVEVdqrCKNwMNKYTVEV-VADGCS
.. ..| . . . ... ... .|. ... . .|... |
re................................................kcaqywp...gev.tygdftvtllseeh...ldd.ytvrtlllenldldd
EATFAKVYNCTTWPWKSYPDDVKKVLALVRAPVKESSP-----TVGKQPPVIVMCDLGLDRSATVVLTSIIIEQVldgkTPDCDDLFRKMRDQRAG-VFT
. . | .. || . ||... .|..... . . . .. ||.|.| |..|..|... ...... . | .. ....|.|| | ...
ltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtliaaylmllll....gvdleeavkllreqRpgkavq
MSIFFTYAIRAALFYL
.. . ..|.|..|
tpsqyrflyeallell
|
|||||||||
| subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 113-412 | 1.9e-27 | 91.0 | In-house | 26-269 (274) | alignment | ||
Range on Protein: 113-412
Range on HMM: 26-269/274.0
EKNVNKNRTKDVKLIDATRVVLTNPEKSkmgpaDDVEGYINASHIR-FDNASTDYILTQYPLPSTIRDFWKMVYVTKVTQVITIfEPIKDEAI-EEFANF
.. .||| |.. . .||.|.. . . |. |||| .|. .|. |. |. || |||.|. |||.|.| ..|. .. . .|.. |
fgsqtknryktilPnensrvllesesse.....dedssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivml.tklkeaneqkCavyf
PapaspvpppptasskdigsspdqqprereqieiksircdnhlhqsffplstdhylN-----L-------EgwlintraveVDQRCKNWMNKYTVE-VVA
| . . | . . .. |.|.|. .|
P.......................................................daedyeiserygdve..........ikvekiverndysvrklvl
DGCSEATFAKVYNCTTWPWKSYPDDVKKVLALVRAPVKESSPTVGKQPPVIVMCDLGLDRSATVVLTSIIIEQVLDGKTPDCDDLFRKMRDQRAGVFTMS
... | | | || . |||....| ||. .. . . | ||.| | |. | . .|| . |. . .. | . ..| .| |. |
kylerersvkhywytdWPdhksPddantlldlvleveesreeenaklapvvvhCsaGiGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqts
IFFTYAIRAALFYLK
. . || |||
eqyelihralclylk
|
|||||||||
| subfamily_PTPRB_pd | Subfamily PTPRB | 106-392 | 4.2e-25 | 83.4 | In-house | 42-266 (293) | alignment | ||
Range on Protein: 106-392
Range on HMM: 42-266/293.0
KCTFNEWEKNVNKNRTKDVKLIDATRVVLTNPEKSKMgpaDDvegYINASHIRFDNASTDYILTQYPLPSTIRDFWKMVYVTKVTQVITIFEPIKDEAIE
.....| ..| .||| ... |..|| |.. .... .| ||||..|. |. ..| || |||.|. |||.||. .|.. .. . . . .
avkaaelavnraknrytnilpydhsrvkLaalkdesg...sD...YinanyipgynsprefiatqGPlpetvddfWrmvwekkssiivmltqlvekgkvk
EFANFPAPaspvpppptasskdigsspdqqprereqieiksircdnhlhqsffplstdhylnleGWLINTRAVEVDQRCKNWMNKYTVE-VVADGCSEAT
.|| .. ..|. .. ...... . .| .
CeeYWPad........................................................eepvlyGdikvtlvaeeeledwvirelkiekekeer
FAKVYNCTTWPWKSYPDDVKKVLALVRApVKESSPTVGKQPPVIVMCDLGLDRSATVVLTSIIIEQVLDGKTPDCDDLFRKMRDQRAG
. |. |.|| |.. |..|..||. |.|. . .. |..| | |. |. | . ..... . . | . ..| .|.
kvrqyhftsWpdhgvPektktlldfvrt.vreaiektaskrPivvhCsaGvGRtGtfialdrllqaieeedyvdifgivaelReeRnl
|
|||||||||
| 0041856 | (Phosphotyrosine protein) phosphatases II | 115-411 | 6.5e-22 | 73.4 | In-house | 1-171 (182) | alignment | ||
Range on Protein: 115-411
Range on HMM: 1-171/182.0
NVNKNRTKDVKLIDATRvvltnpekskmgpaddVEGYINASHIRFDNASTDYILTQYPLPSTIRDFWKMVYVTKVTQVITIFepikdeaieE----Fanf
|..|||..|. .| .| . ||||. .... .|..|.|| ||.||. ||..|.. ..| .... |
nldknrysdilpydhsr................dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt.........eelywp...
papaspvpppptasskdigsspdqqprereqieiksircdnhlhqsffplstdhylnlegwlintravevdqrcknwmnkytvevvadgcseA---TFAK
............................................................................................ellerlgi
VYNCTTWPWKSYPDdVKKVLALVRAPVKessptvgKQPPVIVMCDLGLDRSATVVLTSIIIEQvldgkTPDCDDLFRKMRDQRAGVFTMSIFFTYAIRAA
| .. || . || . ..|..... . .. ||.| | |..|..|.|. ..... . .. .. .| .| |.... .. . .|.
qylylpwpDhgvpd.ldelldfieevle.......eggpvlVHCsaGvgRtgtlvaaylmkkl.....gvsleeavklvrsrRpgmvitpnqyfflqlal
LFYL
|..|
lell
|
|||||||||
| subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 248-416 | 1.5e-21 | 71.1 | In-house | 129-290 (302) | alignment | ||
Range on Protein: 248-416
Range on HMM: 129-290/302.0
RCDNhLHQSFFPLSTDHYLNLEGWLINTRAVEVDQRCKnwmNKYTVEVVADGCSEATFAKVYNCTTWPWKSYPDDVKKVLALVRApVkeSSPTVGKQPPV
... . .||. .. |.. . .|.| || . | ..|..||. .|||.. .|.|| .| |. |. |. . .. . . | .. . ..
elkk.tlselfpkksgdykeygkmfvNnrkVekaeeek...tryviEvlPegcsnsvlanvyvltnWkqkkvpvkyaeliktaak.v..fakkikadent
IVMCDLGLDRSATVVLTSIIIEQVLDGKTPDCDDLFRKMRDQRAGVFTMSIFFTYAIRAALFYLKLKLQ
... | | .... . .|.. .|| | .. ...| ||. . . .. .|.|.|.| |..
vivSknGaGRagafltlavaveklqkgkepnikeivksiRsqRpravdslkQyvslyialllyikkkvt
|
|||||||||
| Y_phosphatase | Protein-tyrosine phosphatase | 115-201 | 4.1e-20 | 67.6 | Pfam-A | 1-79 (235) | alignment | ||
Range on Protein: 115-201
Range on HMM: 1-79/235.0
NVNKNRTKDVKLIDATRVVLtnpeKSKMGPADdvegYINASHIRFDNASTDYILTQYPLPSTIRDFWKMVYVTKVTQVITIFEPIKD
| .||| ||. .| ||| | |.. || | ||||.... . . .|.|| ||.||| |||.||. ||. .... . .
nkkknRykdilpydktrvkl....kgsegpsd....YInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleek
|
|||||||||
| Y_phosphatase | Protein-tyrosine phosphatase | 115-201 | 4.1e-20 | 67.6 | In-house | 1-79 (235) | alignment | ||
Range on Protein: 115-201
Range on HMM: 1-79/235.0
NVNKNRTKDVKLIDATRVVLtnpeKSKMGPADdvegYINASHIRFDNASTDYILTQYPLPSTIRDFWKMVYVTKVTQVITIFEPIKD
| .||| ||. .| ||| | |.. || | ||||.... . . .|.|| ||.||| |||.||. ||. .... . .
nkkknRykdilpydktrvkl....kgsegpsd....YInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleek
|
|||||||||
| PTPc_DSPc_SM00012 | 307-408 | 4.3e-19 | 64.0 | In-house | 3-104 (105) | alignment | |||
Range on Protein: 307-408
Range on HMM: 3-104/105.0
KVYNCTTWPWKSYPDDVKKVLALVRApVKESSPTVGKQPPVIVMCDLGLDRSATVVLTSIIIEQVLDG-KTPDCDDLFRKMRDQRAGVFTMSIFFTYAIR
|.| .|.||... |......| |.|| ||.. ....||.|.| | .|..|.|. .|...|. .. |..| ......|.||.|.... . . .|
khyhytgwpdhgvPeesdsilellra.vkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylflyr
AAL
| |
all
|
|||||||||
| subfamily_PTPN12_pd | Subfamily PTPN12 | 110-194 | 7e-18 | 59.5 | In-house | 35-113 (290) | alignment | ||
Range on Protein: 110-194
Range on HMM: 35-113/290.0
NEWEKNVNKNRTKDVKLIDATRVVLTNPEKSKmgpaddVEGYINASHIRFDNASTDYILTQYPLPSTIRDFWKMVYVTKVTQVIT
| |.||.||| ||. | .||.|.. |... ..||||..|. . .. || .| ||| |. |||.|.. ..|. |.
gekeenvkknrykDilPydksrvelskieeee......gsdYinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvm
|
|||||||||
| subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 110-206 | 8.5e-18 | 59.6 | In-house | 51-140 (298) | alignment | ||
Range on Protein: 110-206
Range on HMM: 51-140/298.0
NEWEKNVNKNRTKDVKLIDATRVVLTNPEkskmgpADDVEGYINASHIRFDNASTDYILTQYPLPSTIRDFWKMVYVTKVtQVITIFEPIKDEAIEE
. ..| .||| |. .| .||||.. . ||. |||||.. . .. .|.||.||..|. |||.|| .. ..| ....... .
arkpenkkkNRyadiialdssRvvLeked......adeesdYiNAsflhaykgrnafiatqaPltetvedFWrmvteedi.gtiVmltnleeldktk
|
|||||||||
| subfamily_PTPRD_pd | Subfamily PTPRD | 103-195 | 1.2e-17 | 58.8 | In-house | 36-122 (564) | alignment | ||
Range on Protein: 103-195
Range on HMM: 36-122/564.0
SPSKCTFNEWEKNVNKNRTKDVKLIDATRVVLTNPEKSkmgpadDVEGYINASHIRFDNASTDYILTQYPLPSTIRDFWKMVYVTKVTQVITI
. .... . . | .||| ... |..||||.. |. . |||||.| ... || || ||..||.|||.||. ... .. .
qqftweaankpaNkaKNRyanivaYdhsRVvLskvegd......egsDYINAsfidgyrkrkayIAtqgPlaetiedFWRmvweqnsstiVml
|
|||||||||
| Y_phosphatase | Protein-tyrosine phosphatase | 255-406 | 1.4e-17 | 59.3 | Pfam-A | 85-232 (235) | alignment | ||
Range on Protein: 255-406
Range on HMM: 85-232/235.0
QSFFPLSTDHYLNLEGWLINTRavevdQRCKNWMNK---YTVEVVADGCS-EA-TFaKVYNCTTWPWKSYPDDVKKVLALVRAPVKESsptVGKQPPVIV
. ..| ... .|. . .... .. |..... ...|. .. . | .. |.. .|.|| .. |...|..| |.|. |.. |. ||.|
aqYwpeeeeesltygdikvelk.....ekekedekeytlrklelkkkkeesekrev.kqlhytnWpdhgvpespkslldlirkveksk...eaksgpvvV
MCDLGLDRSATVVLTSIIIEQVLDGKTPDCDDLFRKMRDQRAGVFTMSIFFTYAIRA
.| | |..|.|. .|..||. .....| .. ...| ||.|... . . ..|
hCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmvqsleqYiflyka
|
|||||||||
| Y_phosphatase | Protein-tyrosine phosphatase | 255-406 | 1.4e-17 | 59.3 | In-house | 85-232 (235) | alignment | ||
Range on Protein: 255-406
Range on HMM: 85-232/235.0
QSFFPLSTDHYLNLEGWLINTRavevdQRCKNWMNK---YTVEVVADGCS-EA-TFaKVYNCTTWPWKSYPDDVKKVLALVRAPVKESsptVGKQPPVIV
. ..| ... .|. . .... .. |..... ...|. .. . | .. |.. .|.|| .. |...|..| |.|. |.. |. ||.|
aqYwpeeeeesltygdikvelk.....ekekedekeytlrklelkkkkeesekrev.kqlhytnWpdhgvpespkslldlirkveksk...eaksgpvvV
MCDLGLDRSATVVLTSIIIEQVLDGKTPDCDDLFRKMRDQRAGVFTMSIFFTYAIRA
.| | |..|.|. .|..||. .....| .. ...| ||.|... . . ..|
hCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmvqsleqYiflyka
|
|||||||||
| 0043147 | (Phosphotyrosine protein) phosphatases II | 147-402 | 1.6e-17 | 59.2 | In-house | 3-152 (172) | alignment | ||
Range on Protein: 147-402
Range on HMM: 3-152/172.0
DVEGYINASHIRFDNASTDYILTQYPLPSTIRDFWKMVYVTKVTQVITIFEPikdeaieefanfpapaspvpppptasskdigsspdqqprereqieiks
. . |||||.. . ...| ||.||..|. |||.|.. ..| .... |
egsdyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltel................................................
ircdnhlhqsffplstdhylnlegwlintravevdqrcknwmnkytvevVADGCSEATFAKVYNCTTWPWKSYPdDVKKVLALVRAPVKESspTVGKQPP
. |. . . | .. || . | . . .| ... . . .. |
.................................................lydpellerlgiqylylpwpDhgvp.llellleflefidell..alspggp
VIVMCDLGLDRSATVVLTSIIIeqvldgKTPDCDDLFRKMRDQRAGVFTMSIFFTY
|.| | |..|..|.|. ... . . .. .. .|..| |... . .
vlVHCsaGvgRtgtlvaaylml......lglsleeavalvrekRpgavqnpsqyrf
|
|||||||||
| subfamily_Ptp69D_pd | Subfamily Ptp69D | 95-196 | 1.7e-17 | 58.5 | In-house | 28-123 (307) | alignment | ||
Range on Protein: 95-196
Range on HMM: 28-123/307.0
FDANLANYSPSKCTFNEWEKNVNKNRTKDVKLIDATRVVLTNPekskmgPADDVEGYINASHIRFDNASTDYILTQYPLPSTIRDFWKMVYVTKVTQVIT
.. |. .. .... | . | ||| .|.| | |||.|.. . .. |||||.|. . . ..| | |. .|| |||.|. .|| ..
yekLeareidkstkvsekkenalknRyedikafDktRvkLkki......ngkedsdYinasfikgykekkkfiaaqdPveatigDfWRmiaeqevtlivm
IF
.
ls
|
|||||||||
| subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 86-195 | 4.1e-17 | 57.1 | In-house | 6-106 (285) | alignment | ||
Range on Protein: 86-195
Range on HMM: 6-106/285.0
MKEASLNTYFDANLANYSPSKCTFNEWEKNVNKNRTKDVKLIDATRVVLTNPEKskmgpaDdvegYINASHIRFDN-ASTDYILTQYPLPSTIRDFWKMV
|| ... .. .. | | .||. .| | . || ||. |. ||||| | .. | || || .|. . || || ||| |. |||.|.
mkcqaisklhqdkikgymppnctytayeanpdlnryadvrcieetrvvlknhdr......d....yihaswmrmpgkdqstyittqgplpetlsdfwhmi
YVTKVTQVITI
| |.. |. .
yqekiayvlml
|
|||||||||
| subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 105-391 | 4.7e-17 | 56.5 | In-house | 35-216 (392) | alignment | ||
Range on Protein: 105-391
Range on HMM: 35-216/392.0
SKCTFNEWEKNVNKNRTKDVKLIDATRVVLTNPEKSkmgPADDvegYINASHIRFDNASTDYILTQYPLPSTIRDFWKMVYVTKVTQVITIFEpIKDEAi
.. | . | |..||| |.. .|..||.| . . | .| |.|||.|. .. || .| | .... |||.||. .|| .. . . .|.
ypqtvaqkeinlkknryknilpydsarvkleviddi...pdsd...ylnasyipsfdnekayiasqgpnaaslddfwrmvfqenvttiamvtk.lkegd.
eefanfpapaspvpppptasskdigsspdqqprereqieiksircdnhlhqsffplstdhylnlegwlintravevdqrcknwmnkytvevvaDGCSEAT
| . |
.............................................................................................kgddart
FAKvYNCTTWPWKSYPDDVKKVLALvrapVKESSPTVGKQP-PVIVMCDLGLDRSATVVLTSIIIEQVLDGKTPDCDDLFRKMRDQRA
|. . | || | | . .| . .|| . |. |.|. | |. |.. |. .. . . | .. ..| .|
vaq.fhftewPdkdvpkhtssllkf....ikevkadfGqythpliihcsagvgrtgvvisidsvvahakktrmvdvfnfvtnirrkrp
|
|||||||||
| subfamily_PTPRG_pd | Subfamily PTPRG | 102-211 | 5.8e-17 | 56.1 | In-house | 34-138 (563) | alignment | ||
Range on Protein: 102-211
Range on HMM: 34-138/563.0
YSPSKCTFNEWEKNVNKNRTKDVKLIDATRVVLTNPEKSkmgpaDDVEGYINASHIRFDNASTDYILTQYPLPSTIRDFWKMVYVTKVTQVITIFEPIKD
. .... . ..| .|||. .. .| .|| |.. .. ||||..| . | ..| ||.||..|. |||.|.. .|. ...| . ..
skdldaehsqkpenkrKnRylnivaydrsRvklsplpgk.....kkklDYinAnyidGyqkskafiatqgplkdtfddFWrmiWeqnvaiivmitnlver
EAIEEFANFP
.. ... .|
grrkcdvYWP
|
|||||||||
| subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 110-204 | 6e-17 | 56.7 | In-house | 36-124 (281) | alignment | ||
Range on Protein: 110-204
Range on HMM: 36-124/281.0
NEWEKNVNKNRTKDVKLIDATRVVLTNPEKSKmgpaddVEGYINASHIRFDNASTDYILTQYPLPSTIRDFWKMVYVTKVTQVITIFEPIKDEAI
. ..||.||| ... |||||..|. |..| ||||... . ..|| || |.|... .||.||. .||.... . . |. . .
skadenvlknrYsnivaYDatrvkvtpneenk......ntDYinanfvpgykgekeyiatqgPvPaslvafWqmvweqkvsaivmvtreieagkl
|
|||||||||
| 0051429 | (Phosphotyrosine protein) phosphatases II | 148-413 | 1.3e-16 | 56.5 | In-house | 3-227 (272) | alignment | ||
Range on Protein: 148-413
Range on HMM: 3-227/272.0
VEGYINASHIRFDnasT------DYILTQYPLPSTIRDFWKMvYVTKVTQVITIFEPIKDEAIEEFANFPapaspvpppptasskdigsspdqqprereq
..|||||... . ......||| |..|||.. . ... .... .. .. . |
lsgyiNardvggy...grvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywp..............................
ieiksircdnHLHQSFFPLSTDHYLNLEGWLINTRAVEVDqRCKNWMNKYTVEVVADGCSEATFAKVYNCTTWPWKSYP-DDVKKVLALVRApvkesspt
... ..|. |.. . . . . ... . ... . . . . .|| .. .| || ..| . ....|.|...
..........girylhlpilddsaptilygalrvtllsee.llldyilrellltlllsagearevmhlhytdwpdhgvpqeallellellld........
vgkQPPVIVMCDLGLDRSATVVLTSIIIEQVLDGKTPD--------CDDLFRKMRDQRAGVFTMSIFFTYAIRAALFYLKL
. ||.| | | ||..|||. .....| . | .. ...|.||.|.. .. . .|.| .|.
...ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlyleeaveelraqrpgavqteeqylflyeallellrs
|
|||||||||
| subfamily_PTPN1_pd | Subfamily PTPN1 | 105-211 | 1.7e-16 | 54.8 | In-house | 22-118 (290) | alignment | ||
Range on Protein: 105-211
Range on HMM: 22-118/290.0
SKCTFNEWEKNVNKNRTKDVKLIDATRVVLTNPEKskmgpaddveGYINASHIRFDNASTDYILTQYPLPSTIRDFWKMVYVTKVTQVITIFEPIKDEAI
... . ..| |.|| .||. | .|..| . .. ||||| . ...| ||||| |||.|. ||.||. | |. . . . | |
fptreaklpenrnlnryrdvspydhsrikleradn..........dyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvvekeqi
EEFANFP
. .|
kcaqywP
|
|||||||||
| 0049772 | (Phosphotyrosine protein) phosphatases II | 107-412 | 1.7e-16 | 56.3 | In-house | 38-281 (314) | alignment | ||
Range on Protein: 107-412
Range on HMM: 38-281/314.0
CTFNEWEKNVNKNRTKDVKLIDaTRVVLTnpekskMGPADDvEGYINASHIRFDnasTDYILTQYPLPSTIRDF----------WKMV--YVTKVTQ---
... ..| .|||..|. | .||.| | .. .|||||... ..| ||.||. |. || |.|| . .|
ilvadlflnrdknryldilpad.nrvilp......glpvsg.sdyinasyvdgf...lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivm
----------------------------VitifepikdeaieefanfpapaspvpppptasskdigsspdQQPREREQI--Eiksircdnhlhqsffpls
.| .... .
srdevladelsrLdaAlgKtpllildgng.........................................neptaadlellk..................
tdhylnlegwlintravE-----------------------------VdqrcknwmnkytvevvadgcseatfakvyncttwpwksypddVKKVLALVRA
| ....|.....
.................eelydpelferlgikylripvpDgsaplled..........................................fdeflefiee
PvKessptvgKQPPVIVMCDLGLDRSAT-VVLTSIIIEQvldgKTpDCDDLFRKMRDQRA-----GVFTMSIFFTYAIRAALFYLK
. |. ||.| | | .|..| ||. ... . . . .. .. .| .| | . . . . . .| | |||
a.d.......kggpvlvHCkaGkgRtgtfvvaaylmkll....gv.sleealedvrlkRpinpnpgfieqleqyefilealleylk
|
|||||||||
| subfamily_PTPN23_pd | Subfamily PTPN23 | 113-198 | 2.6e-16 | 54.3 | In-house | 41-117 (288) | alignment | ||
Range on Protein: 113-198
Range on HMM: 41-117/288.0
EKNVNKNRTKDVKLIDATRVVLTnpekskmGPADDvegYINASHIR-FDNASTDYILTQYPLPSTIRDFWKMVYVTKVTQVITIFEP
.....||| .|. | .||.| | || |||||... . |.| || ||.||. |||.||| |. .. . ..
klyseknrsrdilPyDhnRvklr.......gskDD...YinAsfvkdlspgcPdfiatqaPlqstlnDFWlmvyeqkssviVmllsk
|
|||||||||
| subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 109-197 | 4.1e-16 | 53.9 | In-house | 41-123 (288) | alignment | ||
Range on Protein: 109-197
Range on HMM: 41-123/288.0
FNEWEKNVNKNRTKDVKLIDATRVVLTNPEKskmgpaDDVEGYINASHIRFDNASTDYILTQYPLPSTIRDFWKMVYVTKVTQVITIFE
. .| .||| ... .| .|| |.. |. . . |||||.| .. . || || ||..|. |||..|| .|.. .. . |
agrlavnakknRyrnilpyDekrvklkklee......eagaDYinasyidgekkkkkyiatqgPladtvndfWelvyenktstivmlte
|
|||||||||
| subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 78-196 | 8.1e-16 | 53.0 | In-house | 8-121 (305) | alignment | ||
Range on Protein: 78-196
Range on HMM: 8-121/305.0
GLCKYILDMKEASLNTY-FDANLANYSPSKCTFNEWEKNVNKNRTKDVKLIDATRVVLTNPEKSKmgpaddVEGYINASHIRFDNASTDYILTQYPLPST
| .|| ... | ... . .. .... .. |.|..|||.|.. | | |. ||. |. . . |||||.. . . ||..| ||..|
dlaayikearvysdkgleaqykslyeeeesidvgkkeankaknrlkeitlldddriiltekesld......dsdyinasyvdgykrkkkyivaqgPlknt
IRDFWKMVYVTKVTQVITIF
..|||.... .||.... .
vadfWrliveekvstivmlt
|
|||||||||
| subfamily_PTPN14_pd | Subfamily PTPN14 | 88-207 | 1.2e-15 | 52.4 | In-house | 22-136 (300) | alignment | ||
Range on Protein: 88-207
Range on HMM: 22-136/300.0
EASLNTYFDANLANYSPSKCTFNEWEKNVNKNRTKDVKLIDATRVVLTNpEKskmgpaDDVEGYINASHIRFDNAS--TDYILTQYPLPSTIRDFWKMVY
|. . | .. . .... . ..|..|||.||| . .|| |. | .. .||||||.|. .. .|| .| ||. |..|||.||.
egkvfteyeripkkredallstaklpenaeknrfkdvlPyednrvelsp.tk......enstgyinassikvsvggkersyivaqgPleltvqdfWqmvW
VTKVTQVITIFEPIKDEAIEEF
..|. .. . | ..| |
eqgvqlivmlteeeedgkeksf
|
|||||||||
| subfamily_PTPN9_pd | Subfamily PTPN9 | 80-194 | 1.3e-15 | 52.2 | In-house | 7-115 (297) | alignment | ||
Range on Protein: 80-194
Range on HMM: 7-115/297.0
CKYILDMKEASLNTYFDANLANYSPSKCTFNEWEKNVNKNRTKDVKLIDATRVVLTNPEKskmgpaDDVEGYINASHIRFDNASTDYILTQYPLPSTIRD
.|. .... | . . .. . . . |..||| .|| .| |||||.. .. |. ||||... . .| || ||. |..|
vayvkekgkrGlskeyaeirnepveGtflasklranleknrytdvlcydetrvvlakvde......deasdyinanfvdGykqkkafiatqGplkktvsd
FWKMVYVTKVTQVIT
||.||. .| ..
fWrmvWeqevlvivm
|
|||||||||
| subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 109-216 | 2.2e-15 | 51.2 | In-house | 30-132 (287) | alignment | ||
Range on Protein: 109-216
Range on HMM: 30-132/287.0
FNEW--EKNVNKNRTKDVKLIDATRVVLTNpeKSKMGPAddvegYINASHIRFDNASTDYILTQYPLPSTIRDFWKMVYVTKVTQVITIFEPIKDEAIEE
| . .|.||| || || |||.|.. ....| . |||| .. . .| .| |...|.||||..|. |... |||. ... .
fkaaeelaavkknryadvlPiddtrvllsa..egelGsd.....yinanyvasytddeafiaaqgPiaatvrdfwravletrsasvitmtreveearlkc
FANFPAPASP
. .| . |
ykywPerevP
|
|||||||||
| subfamily_PTPN13_pd | Subfamily PTPN13 | 105-195 | 3.4e-15 | 51.0 | In-house | 27-108 (273) | alignment | ||
Range on Protein: 105-195
Range on HMM: 27-108/273.0
SKCTFNEWEKNVNKNRTKDVKLIDATRVVLTNPEKskmgpaddvegYINASHIRF--DNASTDYILTQYPLPSTIRDFWKMVYVTKVTQVITI
.|. . ..| .||| ..| .|.||| | . |||||.|. .. .||..| ||| |..|||.||. |.. .. .
dtcevgkkkenkdknryrnvlPydetrvklgdegg...........yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamv
|
|||||||||
| subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 113-193 | 8.6e-15 | 49.6 | In-house | 7-81 (250) | alignment | ||
Range on Protein: 113-193
Range on HMM: 7-81/250.0
EKNVNKNRTKDVKLIDATRVVLTNPEkskmgpADDVEGYINASHIRFDNASTDYILTQYPLPSTIRDFWKMVYVTKVTQVI
.| .||| |. .| .|||| . . .|. |||||.. . . .| || ||..|| |||.||. |.. ..
pqnkeknryadiialdssrvvLekek......gdkesdyinasflhgyderkafiatqgPlqatiedfWrmvleeksgtiv
|
|||||||||
| 0036282 | (Phosphotyrosine protein) phosphatases II | 150-402 | 9e-15 | 50.3 | In-house | 3-161 (174) | alignment | ||
Range on Protein: 150-402
Range on HMM: 3-161/174.0
GYINASHIRFDNASTDYILTQYPLPstirdFWKMVYVTKVTQVITIFEPIKDEAIEEFANFPApaspvpppptasskdigsspdqqprereqieiksirc
|||||.. . .. .|..|.||. ||.|.. ..| |.. |.. .. . .|
dyinaspldlsyitprliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe.....................................
dnhlhqsffplstdhylnlegwlintravevdqrcknwmnkytvevvaDGCSEATFAKVYNCTTWPWKSYPDDVKkVLALVRAPVKESSPtvGKQPPVIV
. .. . | .. || . ||. . .| .|.. . | ... ||.|
................................................lredlerlgiqylylpwpDhgvpdlsi.llefvkfveealse..dpggpvlV
MCDLGLDRSATVVLTSIIIEQVLdGKTPDCDDLFRKMRDQRAGVFTMSIFFTY
| |..|..|.|. ... . | .. | ||.|..| || |.... .. .
HCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtpsQyrf
|
|||||||||
| subfamily_PTPN3_pd | Subfamily PTPN3 | 104-195 | 9.9e-15 | 49.2 | In-house | 30-115 (280) | alignment | ||
Range on Protein: 104-195
Range on HMM: 30-115/280.0
PSKCTFNEWEKNVNKNRTKDVKLIDATRVVLTNPEkskmgpADdvegYINASHIRFDNAS----TDYILTQYPLPSTIRDFWKMVYVTKVTQVITI
... .|..||| .|. ||||| |.. | .| ||||... .. | . || || ||..| |||.||. |.. .. .
glaisaarkpenlsknryrdilpydatrvklkese......td....yinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqksslivml
|
|||||||||
| subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 112-195 | 1.8e-14 | 48.6 | In-house | 43-120 (318) | alignment | ||
Range on Protein: 112-195
Range on HMM: 43-120/318.0
WEKNVNKNRTKDVKLIDATRVVLTNPEKSKMgpADdvegYINASHIRFDNASTDYILTQYPLPSTIRDFWKMVYVTKVTQVITI
. | .||| .. | ||| |.. |... .| ||||..| ... || .| ||| ||.|||.||. . . ....
epvnkaknryanilaydhtrvkLqmlegeeg..sD....yinanyidGyrrkkayiaaqaPlpetieDfWrmvWeqnsavivml
|
|||||||||
| subfamily_PTPRK_pd | Subfamily PTPRK | 112-197 | 2.4e-14 | 47.9 | In-house | 40-119 (314) | alignment | ||
Range on Protein: 112-197
Range on HMM: 40-119/314.0
WEKNVNKNRTKDVKLIDATRVVLTNPEkskmgpADDVEGYINASHIRFDNASTDYILTQYPLPSTIRDFWKMVYVTKVTQVITIFE
..| .|||..|. | .||.|. . | ||||. | . .. .| ||.||..|..|||..|| . . .. . |
kdenreknrsgdilaydrsrvflitid......gdpssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasivmlte
|
|||||||||
| subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 93-195 | 3.5e-14 | 47.6 | In-house | 23-122 (319) | alignment | ||
Range on Protein: 93-195
Range on HMM: 23-122/319.0
TYFDAN---LANYSPSKCTFNEWEKNVNKNRTKDVKLIDATRVVLTNPEKSKmGpaddvEGYINASHIRFDNASTDYILTQYPLPSTIRDFWKMVYVTKV
|... . | . .. . . . |.| .||| .... .| |||||.. . .. | |||||.| . . .| || || || |||.||. ..
tllekefkllkeavndtfdsaskeenkkknryqnilaydrtrvvlseldgve.g.....sdyinasfidgyqerekfiatqaPlentiedfWrmvWeees
TQVITI
|. .
sivvml
|
|||||||||
| subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 103-202 | 3.5e-14 | 47.4 | In-house | 34-129 (290) | alignment | ||
Range on Protein: 103-202
Range on HMM: 34-129/290.0
SPSKCTFNEWEKNVNKNRTKDVKLIDATRVVLTNpeksKMGPADDVEGYINASHIRFDNASTDYILTQYPLPSTIRDFWKMVYVTKVTQVITIFEPIKDE
|. . | . ..| ..|| ... . | |..| . . | | . ||||..| . . .||.|| |...|..||||... ||| .. . . |...
sehtvtvgltssnkllnRfanivvyddnritLrp....isghkDCtneyinAcyikgykekkqyiatqgpvsntlvdFWkliwqekvtiivmltniieeg
|
|||||||||
| subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 104-193 | 4.8e-14 | 47.0 | In-house | 9-93 (270) | alignment | ||
Range on Protein: 104-193
Range on HMM: 9-93/270.0
PSKCTFNEWEKNVNKNRTKDVKLIDATRVVLtnpE---KskmgpaDDVEGYINASHIR-FDNASTDYILTQYPLPSTIRDFWKMVYVTKVTQVI
.|. .. |. .. . || .|. ||||.| | . |.. |||| ..| ||.... || .. |||.|...||.|.. .||| ..
tsesdlpeaargkklnRyadiLPsPatRvrl...eelee......dsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaiv
|
|||||||||
| subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 81-203 | 7.5e-14 | 46.4 | In-house | 8-121 (307) | alignment | ||
Range on Protein: 81-203
Range on HMM: 8-121/307.0
KYILDMKEASLNTYFDaNLANYSPSKCTFNEWEKNVNKNRTKDVKLIDATRVVLTNPekskmGPADDvegYINASHIRFDNASTDYILTQYPLPSTIRDF
. ||. .| | .||...| | . .. | .||| .||| .| .|.|.. . | | | || | .. .| .| || .|. .|
qrtldkgvqalvdefr.vlakktpegvtveafsantdknryqdvkcqdkgrivvkfd.....glasd...yihanylgiaikpkkficaqgplentqysf
WKMVYVTKVTQVITIFEPIKDEA
| |. || || . . |.
wamaiqekvesvimlckvielak
|
|||||||||
| subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 97-197 | 1.1e-13 | 45.6 | In-house | 22-118 (301) | alignment | ||
Range on Protein: 97-197
Range on HMM: 22-118/301.0
ANLANYSPSKCTFNEWEKNVNKNRTKDVKLIDATRVVLTNPEKSKMgpadDVEGYINASHIRFDNASTDYILTQYPLPSTIRDFWKMVYVTKVTQVITIF
.| .... .|| . |.| . || |... .| |..|.. .. .. . |||||.| . .. .| .| |. .|..|||.... |.......
kelkegedksctvglseenkalnrfknitvyddnriilkpkpnldl....cqreyinasyidgysekkkfiaaqgpmkktlvdfWrliwqekpvsivmvt
E
.
n
|
|||||||||
| subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 109-202 | 2e-13 | 44.9 | In-house | 27-112 (283) | alignment | ||
Range on Protein: 109-202
Range on HMM: 27-112/283.0
FNEWEKNVNKNRTKDVKLIDATRVVLTNPEKskmgpaddveGYINASHIR---FDNASTDYILTQYPLPSTIRDFWKMVYVTKVTQVITiFEPIKDE
. ..| .||| ... | || | . . ||||..| .. . .|| .| || |..||||||. |.| .. . .....
iasadenkrknrnqeivpadqwrvelksesr..........dyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekitaivm.ltklqed
|
|||||||||
| subfamily_PTPRN_pd | Subfamily PTPRN | 99-206 | 2.1e-13 | 44.6 | In-house | 38-141 (297) | alignment | ||
Range on Protein: 99-206
Range on HMM: 38-141/297.0
LANYSP--SKCTFNEWEKNVNKNRTKDVKLIDATRVVLTNPEkskmgpADDVEGYINASHIR-FDNASTDYILTQYPLPSTIRDFWKMVYVTKVTQVITI
|..| | .. . ||||.|||.|.| | .|| |.. ... . ||||| | | .. || || ||.||. |||.||. |. ....
lcayeaepstkevakaeknvkknrskavlpydhsrvklkeea......saeksdyinasaildhdprapayiatqgplastvadfwqmvweqGvvvivnl
FePIKDEAIEE
....| ...
t.rleeegvkq
|
|||||||||
| 0049260 | (Phosphotyrosine protein) phosphatases II | 162-400 | 2.6e-13 | 45.4 | In-house | 7-139 (152) | alignment | ||
Range on Protein: 162-400
Range on HMM: 7-139/152.0
ASTDYILTQYPLPSTIRDFWKMVYVTKVTQVITIFEPIKDEAIEEFANFpapaspvpppptasskdigsspdqqprereqieiksircdnhlhqsffpls
.. .| ||.|.| |. |||.|.. ..| .... |. . . . .
mpfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi...................................................
tdhylnlegwlintravevdqrcknwmnkytvevvadgcseatfakVYNCTTWPWKSYPDDVKKVLALVRAPVKEsspTVGKQPPVIVMCDLGLDRSATV
| .. || . ||. .| |... | |. ||.| | |..|..|.
..............................................qylhlpwpDhgvpdlsqlllflllfiekl...aldkggpvlVHCsaGvgRtgtl
VLTSIIIeqvldgKTPDCDDLFRKMRDQRAGVFTMSIFF
|. ... . . .. .. .| .| |... .
vaaylml......lgvsleeavalvrekRpgavpnpgql
|
|||||||||
| subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 102-196 | 2.7e-13 | 44.6 | In-house | 34-118 (287) | alignment | ||
Range on Protein: 102-196
Range on HMM: 34-118/287.0
YSPSKCTFNEWEKNVNKNRTKDVKLIDATRVVLTnpekskmgpaDDVEGYINASHIRFDNASTDYILTQYPLPSTIRDFWKMVYVTKVTQVITIF
.. . | | ..| .||| ... | ||.| . . ||||..| . . .|... |. .|.|.|||.. .|| .. .
qredevthniasqnkdknRltqilvpdnyrvllk..........gehpdyinavfidgykekkafiiaesPmfntarnfWkliddrnvtaivmlc
|
|||||||||
| 0046846 | (Phosphotyrosine protein) phosphatases II | 151-411 | 4e-13 | 45.0 | In-house | 14-173 (176) | alignment | ||
Range on Protein: 151-411
Range on HMM: 14-173/176.0
YINASHIRFDnastDYILTQYPLPSTIRDFWKMVYVTKVTQVITIFEPIKDEAIEEFAN--------Fpapaspvpppptasskdigsspdqqprereqi
||||. | . .| ||.|||.|. ||..|.. ..| |... |.. . . . .
yinanlilgs....rpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgi................................
eiksircdnhlhqsffplstdhylnlegwlintravevdqrcknwmnkytvevvadgcseatfakVYNCTTWPWKSYPDDvKKVLALVRAPVKESSPTvg
| .. || . ||. . .| |... . .
.................................................................qylhlpwpDhgvpdl.elllellefirealkeg..
kqPPVIVMCDLGLDRSATVVLTSIIIEqvldGKTPDCDDLFRKMRDQRA-GVFTMSIFFTYAIRAALFYL
||.| | |. |..|.|. ... .| . .. ....|.|| |... . . ...|..|
..gpvlVHCsaGigRtgtlvaayllel....ekglsveealalvreqRplgavqtpeQyrflyefellll
|
|||||||||
| subfamily_PTPN6_pd | Subfamily PTPN6 | 113-192 | 7.9e-13 | 43.1 | In-house | 52-126 (306) | alignment | ||
Range on Protein: 113-192
Range on HMM: 52-126/306.0
EKNVNKNRTKDVKLIDATRVVLTnpEKSKMGpaddvEGYINASHIR--FDNASTDYILTQYPLPSTIRDFWKMVYVTKVTQV
.| .||| | . | |||.|. |.| .| . ||||. |. . . .. || || |..|. |||.||. . . .
penkeknryknilPfDhtrvilk..epsvpg.....sdyinanyikkevkgsdksyiatqgclettvsdFWrmvwqensrvi
|
|||||||||
| subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 100-196 | 1.3e-12 | 42.3 | In-house | 29-119 (315) | alignment | ||
Range on Protein: 100-196
Range on HMM: 29-119/315.0
ANYSPSKCTFNEWEKNVNKNRTKDVKLIDATRVVLTNPEKSkmgPADDvegYINASHIRFDNASTDYILTQYPLPSTIRDFWKMVYVTKVTQVITIF
. ... . . | .||| |.. .| .||.| ..| | .| |||||.|. . || .| ||.... |||.||. .||| .. .
pdPdiyrqrvaretinfkknryknilPldsarvklevidds...Pdsd...yinasyiksvdddkayiasqgPlkasvddfwrmvlqekvttivmvt
|
|||||||||
| subfamily_egg_pd | Subfamily egg | 96-408 | 2e-12 | 41.4 | In-house | 23-267 (307) | alignment | ||
Range on Protein: 96-408
Range on HMM: 23-267/307.0
DANLANYSPSKCTFNEweKNVNKNRTKDVKLIDATRVVLTNPEKSKMGpaddveGYINASHIRFDNASTDYILTQYPLPSTIRDFWKMVYVTKVtQVITI
.... . . .... | .| |.| |. | .|| | .. .. .| | ... . ..||.| || | |||.||. .| | | .
leesvdeislttaasd..nnlekarskrvhckdssrvklelrrGqyld......dfihanrvkGkpllnefilaqaplkntvddfwrmvfqeev.qyivm
FEPIKDEaieefanfpapaspvpppptasskdigsspdqqprereqieiksircdNHLhQSFFPLSTDHYLNLEGWLINTRAVEVDQRCKNWMNKYTVEV
.. |. .. . ..| . .. | . .. ...||.. .. . .
ltsrkes................................................erc.eyywpkaesdslvtvpGslrienlkvdskadplfrvtklkl
VADGcSEATFAKVYNcttWPWKsYPDDVKKVLALVRAPVKESSptvgkqpPVIVMCDLGLDRSATVVLTSIIIEQVLDGktPDCDDL----FRKMRDQRA
| | | . .. . .. . || | ..| . | ||.| . || ..||.| | . ..| | | | .| .|
vGgd.deerflehwq...gdvn.nssdvysplrvlrklrnlsk.......pvvvqdilGvskaatlvaieiallsllrG..pitkslvlravvflrlrrr
GVFTMSIFFTYAIRAAL
. . . | |
lsvesvllylfvyrlvl
|
|||||||||
| subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 108-197 | 2.9e-12 | 40.5 | In-house | 36-119 (515) | alignment | ||
Range on Protein: 108-197
Range on HMM: 36-119/515.0
TFNEWEKNVNKNRTKDVKLIDATRVVLTNPEKSkmgPADDvegYINASHIRFDNASTDYILTQYPLPSTIRDFWKMVYVTKVTQVITIFE
| . | | .||| |.. .| .|| | . . | | |.|||.|. .. || .| |..... |||..|. .|| .. . .
tvaqeeinfkknryknilPydsvrvklevindn...Phsd...yfnasyipsfdndkayiasqgPnkasvddfWrlvlqenvttiamvtk
|
|||||||||
| subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 113-197 | 4.2e-12 | 40.8 | In-house | 46-126 (325) | alignment | ||
Range on Protein: 113-197
Range on HMM: 46-126/325.0
EKNVNKNRTKDVKLIDATRVVLTNpekSKMGPADDvegYINASHIRFDNASTDYILTQYPLPSTIRDFWKMVY--VTKVTQVITIFE
.|..||| |.| .| .|||| | | | |||||..| | .. .| ||..|| |.|..|. . | |. ...
penkaknrfknvvaldksrvvlet...kkddpssd...yinasylrddkkkdvflaaqaPltatindlWrlvldWrcsvvvvlneld
|
|||||||||
| subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 106-195 | 4.3e-12 | 41.1 | In-house | 16-99 (284) | alignment | ||
Range on Protein: 106-195
Range on HMM: 16-99/284.0
KCTFNEWEKNVNKNRTKDVKLIDATRVVLtnpeKSKMGpaDDVEGYINASHIRFDNASTDYILTQYPLPSTIRDFWKMVYVTKVTQVITI
. || . ..| .||| .. | ..| | . .| . |||||.| || || ||. |. |||.|.. ... .. .
dqtfanldqnkdknrighilafdknvvkl....erliG..eefsdyinasfitGyqrkdkyiatqGPldntladfWrmiweyncstivll
|
|||||||||
| subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 105-195 | 4.5e-12 | 40.9 | In-house | 51-135 (319) | alignment | ||
Range on Protein: 105-195
Range on HMM: 51-135/319.0
SKCTFNEWEKNVNKNRTKDVKLIDATRVVLtnpeKSKMGpaDDVEGYINASHIRFDNASTDYILTQYPLPSTIRDFWKMVYVTKVTQVITI
.. || . ..| .||| .. | ..| | . | . |||||.. || .| ||. |. |||.|.. ... .. .
adqtfanldqnkdknriinilafdknvvkl....erliG..eefsdyinasfvtGyqrkdkyiaaqGPldntladfWrmiweyncstivll
|
|||||||||
| subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 96-196 | 6.6e-12 | 39.6 | In-house | 28-115 (303) | alignment | ||
Range on Protein: 96-196
Range on HMM: 28-115/303.0
DANLANYSPSKCTFNEWEKNVNKNRTKDVKLIDATRVVLTNpekskmgpaddvEGYINASHIRFDnASTDYILTQYPLPSTIRDFWKMVYVTKVTQVITI
....| | . . |.. ||..||| || .| ..| |.. || ||.. .| .| |||| ||. | |||.|. || |. .
fekvvsylppsvsknqfvknmdknrfvdvicldhskvklsd............ssyihasyleld.sskkailtqlplshtaadfwqmiieqkvkcvlll
F
.
l
|
|||||||||
| subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 104-194 | 6.7e-12 | 39.6 | In-house | 41-124 (310) | alignment | ||
Range on Protein: 104-194
Range on HMM: 41-124/310.0
PSKCTFNEWEKNVNKNRTKDVKLIDATRVVLTNpEKSKMgpaddvEGYINASHIRFDNASTDYILTQYPLPSTIRDFWKMVYVTKVTQVIT
| |.. ..|.. ||| || |..|| |. .||. | || | ... . . .| .| || || |||.|.. . ..
dssltyeaykkymhknrysdvvcldtsrvklki.dksry......edyihanyvktnylrstficsqgplqhtiidfwrmifqeraesill
|
|||||||||
| subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 83-207 | 7.9e-12 | 39.2 | In-house | 20-137 (302) | alignment | ||
Range on Protein: 83-207
Range on HMM: 20-137/302.0
ILDMKEASLNTYFdANLANY--SPSKCtfNEWEKNVNKNRTKDVKLIDATRVVLTNPEkskmgpaddvEGYINASHIRFDNASTDYILTQYPLPSTI---
. ...|.... | .... . || . . ||..||...||...|...| |.. . . |.|||.. . . ||.| | ..
vksldtaevkkef.kkidtmkvdlekC..kafkknlkknqsedvpildsnlvkleaep..........dsyvnaskvevPeltrsiilaQlpkvdsedsv
RDFWKMVYVTKVTQVITIFEPIKD-EAIEEF
.||.||. |...| . . . ....|.
eeFWrmvfqekivsvvilvgeeelkktlsel
|
|||||||||
| subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 288-393 | 9.8e-12 | 39.5 | In-house | 156-262 (318) | alignment | ||
Range on Protein: 288-393
Range on HMM: 156-262/318.0
MNKYT---VEVVADGCSEATFAKVYNCTTWPWKSYPDDVKKVLALVRApVKESSPTVGKQpPVIVMCDLGLDRSATVVLTSIIIEQVLDGKTPDCDDLFR
...|. ..| ....| . |..|.|| .. |... ..|.||| |.. . |.. |..| | | | . . .|..|.. . .. | . .
lsdyvlrefkvtrteeeesrqvrqyhytsWpdegvpesgaslldlvrq.vskaqqksgag.pivvhCsaGvGrtGvfiavdillerikaealvDvfqtvk
KMRDQRAGV
..|.|| .
qlreqrnlm
|
|||||||||
| 0044763 | (Phosphotyrosine protein) phosphatases II | 150-398 | 1.1e-11 | 40.2 | In-house | 19-158 (178) | alignment | ||
Range on Protein: 150-398
Range on HMM: 19-158/178.0
GYINASHIRfDNastdYILTQYPLpstiRDFWKMVYVTKVTQVITIFEPIKDEAIEEFANFPAPASpvpppptasskdigsspdqqprereqieiksirc
|||||.| .. ..|...| |...... ..| .... |.. ..... .| |.
dyinaseil.pg....lylgslpp....addlellkelgithivnlteelelgflkcdpywpeeag..................................
dnhlhqsffplstdhylnlegwlintravevdqrcknwmnkytvevvadgcseatfaKVYNCTTWPWKSYPDDVKKVLALVRAPVKESSptvGKQPPVIV
| .. .| . || . .|..|.. . . |. ||.|
.........................................................iqylhipipDhgvpdllehflefvefieeald...ekggpvlV
MCDLGLDRSATVVLTSIIIEQvldgkTPDCDDLFRKMRDQRAgVFTMSI
| |..||.|.|. ..... . .. .. .| .| ...
HCsaGvgRsgtlvaaylmkkl.....glsleeaielvrerRp.ivpnpg
|
|||||||||
| subfamily_PTPRA_pd | Subfamily PTPRA | 104-195 | 1.2e-11 | 39.1 | In-house | 47-132 (330) | alignment | ||
Range on Protein: 104-195
Range on HMM: 47-132/330.0
PSKCTFNEWEKNVNKNRTKDVKLIDATRVVLTNPEKSkmgpadDVEGYINASHIRFDNASTDYILTQYPLPSTIRDFWKMVYVTKVTQVITI
. . . |.| .||| .. | .||.|.. | . |||||.| . .| .| |. |. |||.|.. | . .. .
qatlelaskeenkeknrvvnilPydfsrvilsvkeGv......eesdyinasfidGykekdkfiaaqGPkeetvedfwrmiweqksativml
|
|||||||||
| subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 114-199 | 1.3e-11 | 39.0 | In-house | 48-127 (315) | alignment | ||
Range on Protein: 114-199
Range on HMM: 48-127/315.0
KNVNKNRTKDVKLIDATRVVLTNPEKskmgpaDDVEGYINASHIRFDNASTDYILTQYPLPSTIRDFWKMVYVTKVTQVITIFEPI
.|..||| .. | .|| | |. |. |.||. | | || .| |......|||..|. ...... . . .
enkqknryiniiaydksrvqlpllen......dphsdyvnanfidGynkkrryiaaqgpnvasvkdfwrlvfeedigkivmltnlv
|
|||||||||
| subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 99-202 | 1.9e-11 | 38.1 | In-house | 37-132 (290) | alignment | ||
Range on Protein: 99-202
Range on HMM: 37-132/290.0
LANYSPSKCT-FNEWEKNV--NKNRTKDVKLIDATRVVLTNpekskMGPADdvegYINASHIRFDNAstDYILTQYPLPSTIRDFWKMVYVTKVTQVITI
| | |.. . ..|| .||| ||| | |||.| . .. | |. | ... .| .|||| .| .|. |.|.|| .||. .. .
lkpylpvqylerkifdkntefkknrykdvvcndktrvilkd.....GydGd....yvhanyvkGlka..mfiltqGalkdtvidiwrmvlqekvaaivml
FEPIKDE
| |.|
celiedG
|
|||||||||
| subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 115-195 | 2e-11 | 38.3 | In-house | 47-135 (350) | alignment | ||
Range on Protein: 115-195
Range on HMM: 47-135/350.0
NVNKNRTKDVKLIDATRVVLTNPEKSKMGPAD--DVEGYINASHIRFD------NASTDYILTQYPLPSTIRDFWKMVYVTKVTQVITI
||| |.. . .|| | . || . . ||||.... |.. || || |||||. ||.|... ||. ....
lfaknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsl
|
|||||||||
| subfamily_CG7180_pd | Subfamily CG7180 | 104-196 | 2.6e-11 | 37.7 | In-house | 31-117 (296) | alignment | ||
Range on Protein: 104-196
Range on HMM: 31-117/296.0
PSKCTFNEWEKNVNKNRTKDVKLIDATRVVLTNPEkskmGPADDVegYINASHIRFDNASTDYILTQYPLPSTIRDFWKMVYVTKVTQVITIF
.| . ..| .||| .| | .||||.. . | ... ||||... .|| |. | .|. .||..|| .. |. .
igdCagglrkenreknrdvkvvPyDynRvvLekld....Geeksd..YinavyvdsflkkkeyivteapkketvdefWrlvydeeisavvvLt
|
|||||||||
| subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 304-410 | 4.4e-11 | 37.4 | In-house | 137-241 (250) | alignment | ||
Range on Protein: 304-410
Range on HMM: 137-241/250.0
TFAKVYNCTTWPWKSYPDDVKKVLALVRaPVKESSPTVGKQpPVIVMCDLGLDRSATVVLTSIIIEQVLDGKTPDCDDLFRKMRDQRAGVFTMSIFFTYA
. .. ..|| |. |. . ||.|.. |. | . .|.. |||| | | || . . . ..|.. |. | .. ...| .| .. . . .
rivrqlhfvvWPdkgvPevatavLellk.kvqasqqqagna.PvivqCsaGvgrsGafiaidavlerlkkekvvdvfkvikvlrkdrphavesleqyvfv
IRAALFY
...| .
yeiilka
|
|||||||||
| subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 302-411 | 1.1e-10 | 36.2 | In-house | 183-290 (298) | alignment | ||
Range on Protein: 302-411
Range on HMM: 183-290/298.0
EATFAKVYNCTTWPWKSYPDDVKKVLALVRApVKEsSPTVGKQPPVIVMCDLGLDRSATVVLTSIIIEQVLDGKTPDCDDLFRKMRDQRAGVFTMSIFFT
. . . |.|| |. | . ||.|.| |. |.. .. |||| | | .|| | . . ..|.| .. | . . .| .|.|. . ..
kerevrqlhftsWpdkgvpenatsvldllrk.vra.sqqqagnkpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqteeqYv
YAIRAALFYL
. | | .|
fiyeavleal
|
|||||||||
| 0051082 | (Phosphotyrosine protein) phosphatases II | 148-402 | 1.4e-10 | 36.4 | In-house | 2-144 (151) | alignment | ||
Range on Protein: 148-402
Range on HMM: 2-144/151.0
VEGYINASHIRFDnastdYILTQYPLPstirDFWKMVYVTKVTQVITIFEPIKDE---AIEEFANfpapaspvpppptasskdigsspdqqprereqiei
...|||.| . ......||. ||..... ... .... .. . . . ..
lsdyinfsyvtgg.....lyrsggpla....dflellkelgiktivnlrseeergycpeylpelg...................................
ksircdnhlhQ-------------SffplstdhylnlegwlintravevdqrcknwmnkytvevvadgcseatfakvyncttwpWKSYPDDVKKVLALVR
. ..| |...| |..
..........ievlhipildwpdpg...........................................................lplsfdavleflelll
ApvkessptvGKQPPVIVMCDLGLDRSATVVLTSIIIEQvldgktPDCDDLFRKMRDQRAGVFTMSIFFTY
. |. ||.| | |..|..|.|. ..... . .. .. .| .| ||.. . | .
d.........kkngpvlvHCsaGkgRTGtlvalylmllg......vsleealeeyrlkrpgvvqpnqqflf
|
|||||||||
| subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 98-197 | 1.6e-10 | 35.1 | In-house | 19-114 (281) | alignment | ||
Range on Protein: 98-197
Range on HMM: 19-114/281.0
NLANYSPSK-CTFNEWEKNVNKNRTKDVKLIDATRVVLtnpeKSKMgPADDVEGYINASHIRFDNASTDYILTQYPLPSTIRDFWKMVYVTKVTQVITIF
|| || || . | .||| .. .| .|| | | || | . || | .|| ||||| | | |||.|.. . | .. .
nlpgdppsdlctvfnqpvnnkknrylnipcldisrvql....kvkm.pnknstdyihanyirspflkrgyiltqgpkketradfwrmiwqenttaivmlc
E
.
q
|
|||||||||
| subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 108-195 | 2.1e-10 | 35.2 | In-house | 44-123 (297) | alignment | ||
Range on Protein: 108-195
Range on HMM: 44-123/297.0
TFNEWEKNVNKNRTKDVKLIDATRVVLTNPEKSkmgPADDvegYINASHIRFDNAstDYILTQYPLPSTIRDFWKMVYVTKVTQVITI
| | | .|.| |.. .| || | ... | | |.|||... . .| || | ..|. |||.||. .|. .. .
tvaekkvnfeksRYkniLPydssRvkLaivndd...pdsD...yvnasfvkgnkh..rlittqmPmkatvadfWamvldeqvstivml
|
|||||||||
| subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 114-196 | 2.4e-10 | 35.0 | In-house | 2-77 (237) | alignment | ||
Range on Protein: 114-196
Range on HMM: 2-77/237.0
KNVNKNRTKDVKLIDATRVVLTNPEKSkmgpaddvEGYINASHIR-FDNASTDYILTQYPLPSTIRDFWKMVYVTKVTQVITIF
.| ||| ... | .|||| . . ||||.... || . || .| || |. |||.||. | . .. .
enkiknrygnivaydhsrvvlkgagsg........sdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmlt
|
|||||||||
| subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 105-207 | 3.3e-10 | 34.4 | In-house | 23-114 (267) | alignment | ||
Range on Protein: 105-207
Range on HMM: 23-114/267.0
SKCTFNEWEKNVNKNRTKDVKLIDATRVVLTNPEKSkmgpaddvegYINASHIRFDNASTDYILTQYPLPSTIRDFWKMVYVTKVTqVITIFEPIKDEAI
|... ||| ..|| |. | |||.| . |. |||||.. . .|.|| || || ||.... ||. || . .. . |
stisqsiaeknqernrlddnlpyddtrvilrtkeee..........yinasyvegyktknafivtqdplkntitdfltvihdqkvp.vivlltkvftdni
EEF
|
rlf
|
|||||||||
| subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 96-194 | 4.7e-10 | 33.8 | In-house | 14-106 (297) | alignment | ||
Range on Protein: 96-194
Range on HMM: 14-106/297.0
DANLANYSPSKCTFNEWEKNVNKNRTKDVKLIDATRVVLTNpekskmGPAD-DvegYINASHIRFDNAST--DYILTQYPLPSTIRDFWKMVYVTKVTQV
|. | . . . . . . ||| .|. | ||| | . .... | |||| .. | . . |||.| || .|. |||..|. | .
dllldeargesfssakrnsslrknryrdilatddtrvkllr......viterd...yinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvi
IT
.
vm
|
|||||||||
| subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 277-437 | 1e-09 | 32.6 | In-house | 149-299 (312) | alignment | ||
Range on Protein: 277-437
Range on HMM: 149-299/312.0
AVEVDQRCKNWMNKYTVEVVADGCSEATFAKVYNCTTWPWKSYPDDVKKVLALVRAPVKEssptvgkQPPVIVMCDLGLDRSATVVLTSIIIEQVLDGKT
.|. . |. . . . || . . . |. ..|| . || . | |. | |. . ||| | |. |. |..| .| . .
eieiggkskdkithrvlkvvvkatgqesklnhyqwaswpdhgmpdscdtalrllsavkkd.......kkpviahcsagvgrtgtlaliesmiaalrhprk
PDCDDLFRKMRDQRAGVFTMSIFFTYAIRAALFYLKLKlqCLNeNGNEDVKTMITEALAKV
. | | .| .|| . . ||.|. | .| | | . ||. | . |. ||.
qnvkdsfvllrkdrarsvrvfpqyvyalrcvleflysk..gly.krneqewtkfketyaki
|
|||||||||
| subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 116-195 | 1.1e-09 | 32.1 | In-house | 49-138 (349) | alignment | ||
Range on Protein: 116-195
Range on HMM: 49-138/349.0
VNKNRTKDVKLIDATRVVLTNPEKSKMGP--------ADDVEGYINASHIRFDNASTD--YILTQYPLPSTIRDFWKMVYVTKVTQVITI
||| ||. . .||.| . || . . .. |||| .... . |.. || || |||||. ||.|.. .| |. .
faknrykdilPyehsrvklkkslksskvikastsesdsgklddyinanylkltrisvekkyiatqaPlPstvddfykvillngvklvlsL
|
|||||||||
| subfamily_PTPRD_pd | Subfamily PTPRD | 296-393 | 1.2e-09 | 32.4 | In-house | 169-263 (564) | alignment | ||
Range on Protein: 296-393
Range on HMM: 169-263/564.0
VADGCSEATFAKVYNCTTWPWKSYPDDVKKVLALVRApVKESSPtvGKQPPVIVMCDLGLDRSATVVLTSIIIEQVLDGKTPDCDDLFRKMRDQRAGV
||. . .. | || . |. ...|.|.| |..... .. |..| | | |. | . ....|.. . || | ...| || .
kkkkssesreVrqFhFtsWPdhgvpesatslLdlirk.vralne..pdagPivVhCSaGVGRTGtfividamlerikeektvDiyqyvkalrkqRnam
|
|||||||||
| subfamily_ptpA1_pd | Subfamily ptpA1 | 103-193 | 1.3e-09 | 32.3 | In-house | 35-118 (418) | alignment | ||
Range on Protein: 103-193
Range on HMM: 35-118/418.0
SPSKCTFNEWEKNVNKNRTKDVKLIDATRVVLTNPEkSKMGpaddvEGYINASHIRFdNASTDYILTQYPLPSTIRDFWKMVYVTKVTQVI
||. . . ..| .||| .. .. ||| | . . | | |||| .| ..| || ||| || |||.||. .. ..
gpsetsegdkkhntsknrytnilpvnhtrvqlkkiq.dkeg.....sdyinanyidg.aypkqfictqgplpntiadfwrmvwenrcriiv
|
|||||||||
| subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 106-196 | 1.4e-09 | 31.9 | In-house | 89-168 (244) | alignment | ||
Range on Protein: 106-196
Range on HMM: 89-168/244.0
KCTFNewEKNVNKNRTKDVKLIDATRVVLTnpeKSKMGpaddvEGYINASHIRFDNASTDYILTQYPLPSTIRDFWKMVYVTKVTqVITIF
| .|| .| ||| .| || |. |. || . ||||| . ...|||||.|| | |||||. .| |. ..
kdafn..pnnswknregaglpfdfnrvpls...kgsmg.....ntyinasfvgclgrtaeyiltqhpladtsmdfwkmmlerhvn.vlvvl
|
|||||||||
| subfamily_PTPN12_pd | Subfamily PTPN12 | 278-420 | 1.4e-09 | 32.3 | In-house | 142-286 (290) | alignment | ||
Range on Protein: 278-420
Range on HMM: 142-286/290.0
VEVDQRCKNWMN-KYTVEVVADGC-SEATFAKVYNCTTWPWKSYPDDVKKVLALVRApVKESSPtvGKQPPVIVMCDLGLDRSATVVLTSIIIEQVLDGK
.||.. ..... ... .. . .| . .. | || . | .|..|.|... |.| .. |..| | | | |.. .. |.. ..|
fevtleeekavdddflirtLkveaqkesrkvyqfhYtaWPDhgvPssakslleliel.vrelqe..sedaPlvvhCsaGvGrtGtiiaidyvrellkaek
TPDCDDLF---RKMRDQRAGVFTMSIFFTYAIRAALFYLKLKLQCLNE
.|.. |.| ...| ||| . ... .| . ... .|. ..|
ipeeldvfdlvlelrkqraalvqtkeqyelvykavaelvqkeleiiee
|
|||||||||
| subfamily_PTPN6_pd | Subfamily PTPN6 | 308-416 | 2.4e-09 | 31.6 | In-house | 190-302 (306) | alignment | ||
Range on Protein: 308-416
Range on HMM: 190-302/306.0
VYNCTTWPWKSYPDDVKKVLALVRApVKESSPTVG--KQPPVIVMCDLGLDRSATVVLTSIIIEQVLDGKT---PDCDDLFRKMRDQRAGVFTMSIFFTY
|. ..|| .. | | . ||.... |.. . .. .. |..| | |. | |.... |..... .. | .| ...|.|| |. . . .
qyhfksWPdhgvpkdpgavLdfled.vnrkqeeleeaeagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqteqqykf
AIRAALFYLKLKLQ
.| .|.. | .
vykaikkyietkkk
|
|||||||||
| subfamily_PTPN13_pd | Subfamily PTPN13 | 286-412 | 2.7e-09 | 31.7 | In-house | 148-270 (273) | alignment | ||
Range on Protein: 286-412
Range on HMM: 148-270/273.0
NWMNKYTVEVVADGCSEATFAKVYNCTTWPWKSYPDDVKKVLALVRApVKESSPtvgKQPPVIVMCDLGLDRSATVVLTSIIIEQVLDGKTPDCDDLFRK
. .. ...| .|. | ..|| . | ...| .|. |.. .. |..| | |. || |.. .... . | | .. ||
dgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaellqfvae.vrrlqt...dagPivvhcsaGiGrsGtlitidvvlglierdkefdvkeivrk
MRDQRAGVFTMSIFFTYAIRAALFYLK
.|.|| || . . . .|.| ||
lreqrqgvvqtkdqyifvykailevlk
|
|||||||||
| subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 105-199 | 3.4e-09 | 31.2 | In-house | 33-117 (288) | alignment | ||
Range on Protein: 105-199
Range on HMM: 33-117/288.0
SKCTFNEWEKNVNKNRTKDVKLIDATRVVLTnpekskmgpaDDVEGYINASHIRFDNASTDYILTQYPLPSTIRDFWKMVYVTKVTQVITIFEPI
|. . ... .| ..| ... |.||| |. || . ||.| . . | .| || .|| .|||. .. | .. . | .
sidiidsfianptrdryenlprcditrvkls..........ddpdfyiaanvvssakykrrlicaqaPlngtieelWkmllesdveyivmlcell
|
|||||||||
| subfamily_PTPN3_pd | Subfamily PTPN3 | 311-397 | 4.9e-09 | 30.5 | In-house | 178-261 (280) | alignment | ||
Range on Protein: 311-397
Range on HMM: 178-261/280.0
CTTWPWKSYPDDVKKVLALVRApVKESSptVGKQPPVIVMCDLGLDRSATVVLTSIIIEQVLDGKTPDCDDLFRKMRDQRAGVFTMS
. || .. ||| ...| .|. |.. ||. ||.| | |..|. ..| . . . . |. |.|||||| . .
ylaWpdhgvPddsadflefver.vrklr..sgkeePvvvhCsaGigrtGvlilletalalieaaepvypldivrtmrdqramlvqta
|
|||||||||
| subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 108-197 | 5.6e-09 | 30.1 | In-house | 42-121 (305) | alignment | ||
Range on Protein: 108-197
Range on HMM: 42-121/305.0
TFNEwEKNVNKNRTKDVKLIDATRVVLTNPEkskmgPADdvegYINASHIRFDNASTDYILTQYPLPSTIRDFWKMVYVTKVTQVITIFE
.| | .. .||| ||| .| || | .| | . || | .. . .| || || | ||| | . || ... . .
afke.aqeagknrykdvgcldnnrvklegpw.....phe....yihanyvstptnpkrfictqaplektcadfwymclqdkveaifmlcn
|
|||||||||
| subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 107-195 | 5.7e-09 | 29.9 | In-house | 38-122 (439) | alignment | ||
Range on Protein: 107-195
Range on HMM: 38-122/439.0
C--TFNEWEKNVNKNRTKDVKLIDATRVVLTNpekskmGPADDVEGYINASHIRFDNASTDYILTQYPLPSTIRDFWKMVYVTKVTQVITI
| .. | . ||| ||| | |||.| . | |||| .|. || ||.| | |||..|. |.......
ciaslaaqeydqtknrykdvgafdhtrvtlqe......ipgvphshyinanyikGyyddklyiatqgpkkettddfwrlviekktvtivml
|
|||||||||
| subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 254-400 | 7.4e-09 | 30.1 | In-house | 94-229 (239) | alignment | ||
Range on Protein: 254-400
Range on HMM: 94-229/239.0
HQsFFPLSTDHYLNLEGWLINTRaVEVDQrcknWMNKYTVEVVadGCSEATFAKVYNCTTWPWKSYPDDVKKVLALVRAPVKESSPtvGKQpPVIVMCDL
|| ..| || .| || | .| | | . . . | | .| . | | || | |. || | | |.| | | . | .. |
hq.ywpdstskycnlrvtlrkte.vfady....iirtfvmsqv..gqteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslp..gar.pwvihcsa
GLDRSATVVLTSIIIEQVLDGKTPDCDDLFRKMRDQRAGVFTMSIFF
|. |. .... .. | || | . . .|..| . | .
gvgrtgaflvidamlrqakkqktvdifnyvkairedrphmvqtseqy
|
|||||||||
| subfamily_Ptp69D_pd | Subfamily Ptp69D | 308-410 | 7.5e-09 | 30.1 | In-house | 186-285 (307) | alignment | ||
Range on Protein: 308-410
Range on HMM: 186-285/307.0
VYNCTTWPWKSYPDDVKKVLALVRAPVKESSPTvgkQPPVIVMCDLGLDRSATVVLTSIIIEQVLDGKTPDCDDLFRKMRDQRAGVFTMSIFFTYAIRAA
|. |.|. |. . .| |.. . . . |..| | .| .||...| .....|. .. | . ...| || ... ... ||
qyhytgWkDskvPevargllklieqvrelykln...rsPivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnllvqsleqYvflyral
LFY
| |
ldy
|
|||||||||
| subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 254-399 | 8.1e-09 | 30.0 | In-house | 95-229 (239) | alignment | ||
Range on Protein: 254-399
Range on HMM: 95-229/239.0
HQsFFPLSTDHYLNLEGWLINTRaVEVDQrcknWMNKYTVEVVadGCSEATFAKVYNCTTWPWKSYPDDVKKVLALVRAPVKESSPtvGKQpPVIVMCDL
|| ..| || .| || | .| | | . . . | | .| . | | || | |. || | | |.| | | . | .. |
hq.ywpdstskycnlrvtlrkte.vfady....iirtfvmsqv..gqteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslp..gar.pwvihcsa
GLDRSATVVLTSIIIEQVLDGKTPDCDDLFRKMRDQRAGVFTMSIF
|. |. .... .. | || | . . .|..| . |
gvgrtgaflvidamlrqakkqktvdifnyvkairedrphmvqtseq
|
|||||||||
| subfamily_PTPN14_pd | Subfamily PTPN14 | 311-396 | 8.6e-09 | 29.8 | In-house | 190-281 (300) | alignment | ||
Range on Protein: 311-396
Range on HMM: 190-281/300.0
CTTWPWKSYPDDVKKVLAL------VRAPVKESSPTVGKQPPVIVMCDLGLDRSATVVLTSIIIEQVLDGKTPDCDDLFRKMRDQRAGVFTM
| || . |.|||. | || ....... ..|||.| | | |. ..|. ..|. . ... | . ....| || .
ytDWpdhgvPeDvkgflsyLeevqsvrrktnseveskeskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLreqrmllvqt
|
|||||||||
| subfamily_eak_pd | Subfamily eak | 115-207 | 1e-08 | 29.0 | In-house | 52-135 (332) | alignment | ||
Range on Protein: 115-207
Range on HMM: 52-135/332.0
NVNKNrTKDVKLIDATRVVLTNPEKSKmgpaddvEGYINASHIRFDNASTDYILTQYPLPSTIRDFWKMVYVTKVTQVITIFEPIKdEAIEEF
.||.| .. | | ||. . . .|||||| . | . |||| . . . ||.||. | .. . | .. . .|..
avnrn.vvkivpydrylvrltssqlnr.......lGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledve.lkleks
|
|||||||||
| subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 258-414 | 1.1e-08 | 29.4 | In-house | 110-267 (270) | alignment | ||
Range on Protein: 258-414
Range on HMM: 110-267/270.0
FPLSTDHYLNLEGWLINTRAVEVDQRckNWMNKYTVEVVADGCSEATFakVYNCTTWPWKSYPDDVK------KVLALVRApVKESSPTVGKQPPVIVMC
.| .... ..|| |...|.. .. . . ... .| .. . .||| .. | . ..|...|| |..|. |. |..| |
Wpaepkekvkledgkikvlalseeke..egyiltrlrleekgeerrlv..HfwyntWpdhgvpreedsslstdqllkmlra.vrrsekeldkaePllvHc
DLGLDRSATVVLTSIIIEQVLDGKTPDCDDLFRKMRDQRAGVFTMSIFFTYAIRAALFYLKLK
|..|. |.... |... . | |. . ...| .| . . .... .| . | . .
saGvgRtGtlialDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyeflykavveyaerr
|
|||||||||
| subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 259-406 | 1.8e-08 | 28.4 | In-house | 141-278 (290) | alignment | ||
Range on Protein: 259-406
Range on HMM: 141-278/290.0
PLSTDHYLNLEGWLINTrAVEVDQRCKNWMNKYTVEVVADGCSeaTFAKVYNCTTWPWKSYPDDVKKVLALVRAPVKESsptvGkqpPVIVMCDLGLDRS
| . | . . . . | |. . .. .| . .| . | .. .|| || . .| ..|. | | | ||.| | |. |.
pekeGevltfGeitvlc.seeddkdaniikktlsvrdkdsGke..hklkhlkikswpdksvalstlallrtlrilrkas....G...pvvvhcsaGiGrt
ATVVLTSIIIEQVLDGKTPDCDDLFRKMRDQRAGVFTMSIFFTYAIRA
| | . .. .|||| | || | .|. |.. . | . ...
GtfvaievglqilldGkeldlldlvralrnsrlnsvqvdiqylalvei
|
|||||||||
| subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 292-406 | 1.9e-08 | 28.4 | In-house | 174-282 (305) | alignment | ||
Range on Protein: 292-406
Range on HMM: 174-282/305.0
TVEVVADGCSEATFAKVYNCTTWPWKSYPDDVKKVLALVRapvkESSPTVGkqpPVIVMCDLGLDRSATVVLTSIIIEQVLDGKT-PDCDDLFRKMRDQR
|| |. ..| .. | || . | .| |. .. |. | |..| | |. |. .||. |..|.| |. |.| ...|.|.||
tvlviegpgekarkvthyhwidwpdrgvpaadlailelle....karpskg...pivvhcsagigrtgsvvmleyildqllagqiiedtdkilqkireqr
AGVFTMSIFFTYAIRA
. . .
nnsiqtdaqylfvhqv
|
|||||||||
| subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 284-402 | 2.9e-08 | 28.1 | In-house | 154-270 (288) | alignment | ||
Range on Protein: 284-402
Range on HMM: 154-270/288.0
CKNWMNKYTVEVVADG--CSEATfAKVYNCTTWPWKSYPDDVKKVLALVRApVKESSPTVgkQPPVIVMCDLGLDRSATVVLTSIIIEQVLDGKTPDCDD
.. ....... . . .| . . |. ..|| .. |.. . .|.|.| || ... . |.|| | |. |. | . .|..| .. | .
eskeledfvlrklllekkktele.itqyqylaWpdhgvPeskapllellrq.vkvanqad..tgpiivhCsaGvGrtgtFialdalidaveeedyiDvag
LFRKMRDQRAGVFTMSIFFTY
|.| ||| . . .
tvaklRkqRallvqtlkqYef
|
|||||||||
| subfamily_CG42327_pd | Subfamily CG42327 | 120-209 | 5e-08 | 27.0 | In-house | 33-116 (319) | alignment | ||
Range on Protein: 120-209
Range on HMM: 33-116/319.0
RTKDVKLIDATRVVLtnpeksKMGPADDVEGYINASHIR-FDNASTDYILTQYPLPSTIRDFWKMVYVTKVTQVITIFEPIkDEAIEEFAN
| .| . ||||| . . || . |..||..| .|.| . || .| .| .. |||..|. . .... .. . |. |.
rvinvvPlPetrvvl......qrigdddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdls.elGikvcae
|
|||||||||
| subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 334-412 | 5.4e-08 | 26.8 | In-house | 211-290 (305) | alignment | ||
Range on Protein: 334-412
Range on HMM: 211-290/305.0
VKESSPTVGKQPPVIVMCDLGLDRSATVVLTSIIIEQVLDGK-TPDCDDLFRKMRDQRAGVFTMSIFFTYAIRAALFYLK
.. | | . |..| | |. |. |.| |.|.. . | | .| . .||||| . . . | | |.
lellsairgskvpivvhcsagigrtgtivaieyilekiaenkpcppmpelvkalrdqrafsiqndvqylfihrvmlnyfl
|
|||||||||
| subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 301-415 | 6.3e-08 | 27.0 | In-house | 168-275 (288) | alignment | ||
Range on Protein: 301-415
Range on HMM: 168-275/288.0
SEATFAKVYNCTTWPWKSYPDDVKKVLALVRAPvkessptVGKQPPVIVMCDLGLDRSATVVLTSIIIEQVLDGKTPDCDDLFRKMRDQRAGVFTMSIFF
|. . |. |. .. |.. . | |. | |..|.. | |..|..|. |..|.. |. |.|..| . .
eekvivkilhlleWdddgvPenylsplrllevl.......kslqkPivvhssaGvGrtgtlililialeslrlddflgirsllaklreerfkaiqtemqy
TYAIRAALFYLKLKL
|. | | .| ||
lyvhrcvleelllkk
|
|||||||||
| subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 255-434 | 8.1e-08 | 26.7 | In-house | 114-283 (290) | alignment | ||
Range on Protein: 255-434
Range on HMM: 114-283/290.0
QSFFPLSTDHYLNLEGWLINTRAVEVDQRcknwMNKYTVEVVADGCSEATFAKvYNCTTWPWKSYPDDVKKVLALVRApVKEssptvgKQPPVIVMCDLG
. ..| | . |...| .. | .. ... ...| |. | |. . | . ..| | .|.|.. || .. |||| | |
akYvpesvgeelkfkgltvkCkskekedd....vetRelvvkfddeeeftvtH.sllkgWnklnvqedtktllsliqk.vka......sktpvivHcvdG
LDRSATVVLTSIIIEQVL-DGKTPDCDDLFRKMRDQRAGVFTMSIFFTYAIRAALFYLKLKLQCLNENGNE-DVKTMITEAL
. |||.. . . . |. ..| ||| ..| . ..... ....... |. |. .| .|. .|..
iSrsAalaaiilgyQkiaetsgsvkledvlkalrkqralaitsalelafvdagivllaievldqfaeeetekkakaeekety
|
|||||||||
| subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 289-411 | 9.8e-08 | 26.3 | In-house | 163-277 (307) | alignment | ||
Range on Protein: 289-411
Range on HMM: 163-277/307.0
NKYTVEVVADGCSEAtfAKVYNCTTWPWKSYPDDVKKVLALVRApvkesspTVGKQPPVIVMCDLGLDRSATVVLTSIIIEQVLDGKT-PDCDDLFRKMR
| |..|. . | . . .. . || . |. . |. | . ... ||.| | |. || |.| |.. .....|. | ..| ...|
nvttlkvdwaqksrt..iqhlqwenwpdrgvpqinltainllea.......vrydtnpvvvhcsaGvGrsGtivaislvqdkmiaGinckdmkklveelr
DQRAGVFTMSIFFTYAIRAALFYL
.|| . . | | | |.
sqrhyaiqteaqylylhrvlleyf
|
|||||||||
| subfamily_PTPRK_pd | Subfamily PTPRK | 273-394 | 1.3e-07 | 25.7 | In-house | 142-260 (314) | alignment | ||
Range on Protein: 273-394
Range on HMM: 142-260/314.0
INTRAVEVDQRCKNWMNKYTVEVVADGCSEATFAKVYNCTTWPWKSYPDDVKKVLALVRApVKESSPTvgKQPPVIVMCDLGLDRSATVVLTSIIIEQVL
|. ||.. .. . ..|| .| | .| . .. ..|| | . .|.||| ||.|.. .. ...| | | |. | . .|... .
ikvelvetellaelvvrifrveklargqeeirevrqfqflgWpdhdvPvsatgllklvrr.vkksqee..eaGrivvhCsaGaGrtGtfiaidivldmie
DGKTPDCDDLFRKMRDQRAGVF
.. | ...|... .
regvvdvfnavktlrsrkvnmv
|
|||||||||
| subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 297-395 | 1.3e-07 | 26.1 | In-house | 171-267 (305) | alignment | ||
Range on Protein: 297-395
Range on HMM: 171-267/305.0
ADGCSEATFAKVYNCTTWPWKSYPDDVKKVLALVRAPVKESSPtvGKQPPVIVMCDLGLDRSATVVLTSIIIEQVLDGKTPDCDDLFRKMRDQRAGVFT
.|. .| |. |.|| . |. .| |.. |. . .|. |..| | |. |. . . .| .|.. .. | .. ...| .| .. .
ededkesrtvlqyqltdWPdhGvpqfatsllslikrvqkdqkk..dkgvpllVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkmvq
|
|||||||||
| subfamily_PTPN23_pd | Subfamily PTPN23 | 284-404 | 1.4e-07 | 25.7 | In-house | 152-273 (288) | alignment | ||
Range on Protein: 284-404
Range on HMM: 152-273/288.0
CKNWMnKYTVEVVADGCSEATFAKVYNCTTWPWKSYPDDVKKVLALVRAPVK-ESSPTVGKQPPVIVMCDLGLDRSATVVLTSIIIEQVLDGK-TPDCDD
.... ...... . .. . . |.|| |. ...|... . . .. . |..| | | .|. .. | ..... |. .| .
tethv.ervlkletldadavksvshlqltsWpelGvPasPetllqfldevesayeavqrksktPlvvhCsaGvgRtgvfalvyaavrelekgnglldiiq
LFRKMRDQRAGVFTMSIFFTYAI
.....| || . . . .
vvsrlreqRrfmvqekeqlkfsy
|
|||||||||
| subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 307-404 | 1.4e-07 | 25.9 | In-house | 181-279 (319) | alignment | ||
Range on Protein: 307-404
Range on HMM: 181-279/319.0
KVYNCTTWPWKSYPDDVKKVLALVRApVKESSPTVgKQPPVIVMCDLGLDRSATVVLTSIIIEQVLDGKTPDCDDLFRKMRDQRAGVFTMSI---FFTYA
| . | || . |.. . .|.|.. ...| .. |..| | | | | . ....|.| . | ...| || . | .|
khfqyteWpdhdvPekatslldllkr.irksrekt.qsgPivvhCsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyea
I
.
l
|
|||||||||
| 0048076 | (Phosphotyrosine protein) phosphatases II | 306-405 | 1.6e-07 | 26.7 | In-house | 47-137 (145) | alignment | ||
Range on Protein: 306-405
Range on HMM: 47-137/145.0
AKVYNCTTWPWKSYPDDVKKVLALVRAPVK---EssptvgkQPPVIVMCDLGLDRSATVVLTSIIIEqvldgKTPDCDDLFRKMRDQRAGVFTMSIFFTY
| .. || . ||. . .|..... . | ||.| | |..|..|.|. .... . . .. ....| || |... .. .
giqylylpwpDhgvpdllellleflefieealke.......ggpvlVHCsaGvgRtgtlvaaylmll.....lgvsleealelvrsqrpgavpnpgqlrf
AIR
..
lye
|
|||||||||
| subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 289-415 | 1.7e-07 | 25.6 | In-house | 156-280 (281) | alignment | ||
Range on Protein: 289-415
Range on HMM: 156-280/281.0
NKYTVEVVADGCSEATFAKVyNCTTWPWKSYPDDVKKVLALVRApVKESSPTVGKqPPVIVMCDLGLDRSATVVLTSIIIEQVLDG-KTPDCDDLFRKMR
. .... .... . . ... . |.|| . |.. |..| .. |.. . . | |... | | |. | . ....| . .. | ... ...|
ierkfkleresgetreveql.aytaWPdhGvPattkellefrke.vlkltekktk.aplvihCsaGvGrtGtyialDrlvkaveaeleeldvkavvaelr
DQRAGVFTMSIFFTYAIRAALFYLKLKL
.| . . ... .| | .|. .|
kernlmvqtvvqyefvykavldaldkel
|
|||||||||
| subfamily_Cele-PTP-5_pd | Subfamily Cele-PTP-5 | 270-432 | 2.1e-07 | 23.9 | In-house | 175-330 (346) | alignment | ||
Range on Protein: 270-432
Range on HMM: 175-330/346.0
GWLINTRAVEVDQRCKnwmnKYTVEVVADGCSEATFAKVYNCTTWPWKSYPddvKKVLALVRAPVKESSPTVGKQPPVIVMCDLGLDRSATVVLTSIIIE
.|| | .| | .||.||. .| |.. ..|. . | | | | ... . | .. | |. .| |. . . . |.
kmfinnrradvsgdpk....eytievlpegnsdsvicqvhhhapwkhlqqp...pktlpiikmihqflsekqvqnagvcvvslfgcgracsfigalyain
QVLDGKTPDCDDLFRKMRDQRAGVFTmsIFFTY-AIRAALF-YLKLKLQCLNENGNEDVKTMITE
|. .| |. ........|| | | | .| | .| |. | .. | |.. .| |
qlnngiepniceimknikqqrpggve..sfaqyasiyaivfdyiarkrggkkapvnkdinrfide
|
|||||||||
| subfamily_PTPRG_pd | Subfamily PTPRG | 300-402 | 3e-07 | 24.0 | In-house | 179-278 (563) | alignment | ||
Range on Protein: 300-402
Range on HMM: 179-278/563.0
CSEATFAKVYNCTTWPWKSYPDDVKKVLALVRAPVKESSPTVGkqpPVIVMCDLGLDRSATVVLTSIIIEQVLDGKTPDCDDLFRKMRDQRAGVFTMSIF
| . . |..|.|| .. |. || |. . ..| |..| |. | |. | . . ...|. . .. . .. ...| || ...
cdteklvrqyhytkWPdhgvPehslpvLifvkkssaankaeaG...PivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvqteEq
FTY
...
Yif
|
|||||||||
| subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 113-199 | 4.6e-07 | 23.8 | In-house | 53-131 (305) | alignment | ||
Range on Protein: 113-199
Range on HMM: 53-131/305.0
EKNVNKNRTKDVKLIDATRVVLTNPEkskmgPADdvegYINASHIRFDN-ASTDYILTQYPLPSTIRDFWKMVYVTKVTQVITIFEPI
. .. ||| .|| | . | | .| |.| || | .. .| .| || || .|| || || |.. . .
diaitknryqdvpcqdqsavkldkps.....psd....yihanyvgcpmipekrficaqgpldqtidefwwmviqnkveqivmlcktv
|
|||||||||
| subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 115-193 | 5.3e-07 | 24.1 | In-house | 8-81 (239) | alignment | ||
Range on Protein: 115-193
Range on HMM: 8-81/239.0
NVNKNRTKDVKLIDATRVVLtnpEKSKMGPADDvegYINASHIR-FDNASTDYILTQYPLPSTIRDFWKMVYVTKVTQVI
| ||| .. | .|||| || | | |||||..| .| . || || . . |||.|.. . ..
nkaknryanivtydhsrvvl...eklsndphsd...yinasylrdydgspkayiatqgcveissgdfwrmmwqerrcviv
|
|||||||||
| subfamily_PTPRA_pd | Subfamily PTPRA | 288-410 | 5.5e-07 | 23.8 | In-house | 173-294 (330) | alignment | ||
Range on Protein: 288-410
Range on HMM: 173-294/330.0
MNKYTVEVVADGCSEA--TFAKVYNCTTWPWKSYPDDVKKVLALVRApVKESSPTVGKqpPVIVMCDLGLDRSATVVLTSIIIEQVLDGKTPDCDDLFRK
. |. |. ..|.. | . . |.|| | . . .| |... ||. . . |..| | | |. | . . ..|.| . | . ..
vrkflvqqlpdatrekksrlvrqfhftswPdvGvPfepiGmlkllkk.vkklnqqsag..pivvhcsaGvGrtGtfivldavlervkaerkvdvfefvkr
MRDQRAGVFTMSIFFTYAIRAALFY
.| ||. . ... .. | |
lrlqrpqmvqtdeqyefiykvlley
|
|||||||||
| subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 115-193 | 5.6e-07 | 23.9 | In-house | 7-80 (239) | alignment | ||
Range on Protein: 115-193
Range on HMM: 7-80/239.0
NVNKNRTKDVKLIDATRVVLtnpEKSKMGPADDvegYINASHIR-FDNASTDYILTQYPLPSTIRDFWKMVYVTKVTQVI
| ||| .. | .|||| || | | |||||..| .| . || || . . |||.|.. . ..
nkaknryanivtydhsrvvl...eklsndphsd...yinasylrdydgspkayiatqgcveissgdfwrmmwqerrcviv
|
|||||||||
| subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 251-395 | 5.8e-07 | 23.5 | In-house | 129-266 (301) | alignment | ||
Range on Protein: 251-395
Range on HMM: 129-266/301.0
NHLHQSFFPLSTDHYLNLEGWLINTRAVEvdQRCKNWMNKYTVEVVAD-GCSEATFAKVYNCTTWPWKSYPDDVKKVLALVRApVKESsptvgkQPPVIV
.. .....|... . |... . |... | . .. ..| |.||. | .. |. ..|. . | .. |. ||.| . |..|
eekceeylpvkisekldigrfkikiknke..lilnkkiskrtlevedstgkfatrtvthyqysewtdrgvPkshaelfdlmel.vkks......ekPivv
MCDLGLDRSATVVLTSIIIEQVLDGKTPDCDDLFRKMRDQRA-GVFT
| |. || . . | .. .|. .| . . ....|..| || |
hcsaGiGrsvafigteylareveadptieltealkhlrehrwngvqt
|
|||||||||
| subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 287-404 | 6.9e-07 | 23.5 | In-house | 150-265 (285) | alignment | ||
Range on Protein: 287-404
Range on HMM: 150-265/285.0
WMNKYTVEVVADGCSEATFAKVYNCTTWPWKSYPDDVKKVLALVRApVKESSPtvgKQPPVIVMCDLGLDRSATVVLTSIIIEQVLDGKTPDCDDLFRKM
.| || | .|| . . . || . |.| . .. | . ||. | |. |. | | |. |.||.| .... . |. |.|
ilnaltvintedasseplymnhvqvpwwpdqlapedarpmielykw.vkkvnp...kekpicvhcsagvgrtatfvgidyatirimenpniemldivrem
RDQRAGVF--TMSIFFTYAI
| | | ..| | .
ramrfqavqshmqflflyvv
|
|||||||||
| subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 290-396 | 7.2e-07 | 23.6 | In-house | 163-269 (297) | alignment | ||
Range on Protein: 290-396
Range on HMM: 163-269/297.0
KYTVEVVADGCSEATFAKVYNCTTWPWKSYPD--DVKKVLALVrAPVKESSPTVGKQpPVIVMCDLGLDRSATVVLTSIIIEQVLDGKTPDCDDLFRKMR
| ..|| . . | |. . || |. . .....| |. |... .. . |..| | |. | . .. .. .. . |. | .| .|.|
krelevtkgkakarrvvkqyqfveWPdkaverkdsassllkli.sevrkdfsqnaeg.PllvhclaGvGrtgvlltidsvvaeakrekevdifglvkklr
DQRAGVFTM
..| .
qerpylvqt
|
|||||||||
| subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 343-408 | 8.3e-07 | 23.1 | In-house | 227-292 (297) | alignment | ||
Range on Protein: 343-408
Range on HMM: 227-292/297.0
KQPPVIVMCDLGLDRSATVVLTSIIIEQVLDGKTPDCDDLFRKMRDQRAGVFTMSIFFTYAIRAAL
.. ...| | |. || |||. .|.... .. || . ...|.||| . |.. |.|
rnayllvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqtleqfellydavl
|
|||||||||
| subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 308-404 | 1.5e-06 | 21.9 | In-house | 178-272 (439) | alignment | ||
Range on Protein: 308-404
Range on HMM: 178-272/439.0
VYNCTTWPWKSYPDDVKKVLALVRApvKESSPTVGKQPPVIVMCDLGLDRSATVVLTSIIIEQVLDGKTPDCDDLFRKMRDQRAGVFTMSIFFTYAI
. ..|| | | . || ..|| .|. . ||.| | |. |. |.. | .||. . | . . . .|.|| . . .
qfhyiawpdknvpaqashvldflra..insandkeeygpvvvhcsagvGrtGtiialdialeqlklenkvdikgivkvlrkqrkqmvqalcqyvfiy
|
|||||||||
| subfamily_PTPN9_pd | Subfamily PTPN9 | 310-408 | 1.5e-06 | 22.5 | In-house | 179-287 (297) | alignment | ||
Range on Protein: 310-408
Range on HMM: 179-287/297.0
NCTTWPWKSYPDDVKKVLA---LVR-------APVKESSPTVGKQPPVIVMCDLGLDRSATVVLTSIIIEQVLDGKTPDCDDLFRKMRDQRAGVFTMSIF
..|| |.. ...| || . ... ..||..| | |. |. | . | .... . | | . ...| ||| .
qflsWPdyGvPssaaslldvlekvrekqalavkelgdewkghpsgPPivvhcsaGiGrtGtfitldiclsrleevgtvdvvetvkllrtqrafsiqtpeq
FTYAIRAAL
... | |
yefcylavl
|
|||||||||
| 0048179 | (Phosphotyrosine protein) phosphatases II | 307-400 | 1.6e-06 | 23.4 | In-house | 50-134 (144) | alignment | ||
Range on Protein: 307-400
Range on HMM: 50-134/144.0
KVYNCTTWPWKSYPDDVKKVLALVRAPVKESSptvgKQPPVIVMCDLGLDRSATVVLTSIIIeqvlD-GktPDCDDLFRKMRDQRAGVFTMSIFF
| .. || . ||. . .|..... . . . ||.| | |..|..|.|. ... | . .. .. .| .| |... ..
iqylhlpwpDhgvpdllellleflefieeale....eggpvlVHCsaGvgRtgtlvaaylmk....klg..lsleealalvrsrrpgavpnpgql
|
|||||||||
| subfamily_PTPN1_pd | Subfamily PTPN1 | 257-395 | 1.7e-06 | 22.0 | In-house | 116-255 (290) | alignment | ||
Range on Protein: 257-395
Range on HMM: 116-255/290.0
FFPLSTD-HYLNLEGWLINTRAVEVDQRCKNWMNkyTVEVVADGCSEATFAKVYNCTTWPWKSYPDDVKKVLALVRApVKESSPTVGKQPPVIVMCDLGL
..| . . | || .. . .. ... . .. ..|. . |. . |||| . |. . | .. |.|| . .. |... | |.
ywPqgeeekellledtklkvkliseerksyytvr..llelenlktqetreilhfhyttwpdfgvpespaaflkflfk.vresGslssdvGpavihcsaGi
DRSATVVLTSIIIEQVLDGK---TPDCDDLFRKMRDQRAGVFT
|| |..| .. .. . . . | . . ..| .| |.
GrsGtfclvdtclvliekkddlssvdikkvllelrkyrlGliq
|
|||||||||
| subfamily_PTPRN_pd | Subfamily PTPRN | 310-406 | 1.8e-06 | 21.9 | In-house | 193-287 (297) | alignment | ||
Range on Protein: 310-406
Range on HMM: 193-287/297.0
NCTTWPWKSYPDDVKKVLALVRaPVKESspTVGKQPPVIVMCDLGLDRSATVVLTSIIIEQVLDG-KTPDCDDLFRKMRDQRAGVFTMSIFFTYAIRA
.|| .. | | .| . | | | |. |..| | | |. . .| ......| | | | ..||||.|. | .|. |
hflswpeegvPasaksllefrr.kvnks..yrGrscpivvhcsdGaGrtGvyilidlvlnrllkGvkeidiaatlehlrdqrpglvktkdqfefalta
|
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| subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 302-391 | 2.5e-06 | 21.9 | In-house | 131-219 (237) | alignment | ||
Range on Protein: 302-391
Range on HMM: 131-219/237.0
EATFAKVYNCTTWPWKSYPDDVKKVLALvRAPVKESSPTVGKQPPVIVMCDLGLDRSATVVLTSIIIEQVLDGKTPDCDDLFRKMRDQRA
| . . |. |.|| . |. .| . | . . || | . | |. | |. |.. ... .. | . | | . . ..|
evrlihqyqftswpdrgvpqqtaallrf.rkniinrsphvsesgpwiihcsagvgrtgiflvidamlrqakekkvvdiynyvysieedrp
|
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| subfamily_Sponge-PTP-4_pd | Subfamily Sponge-PTP-4 | 149-197 | 2.7e-06 | 21.7 | In-house | 13-60 (130) | alignment | ||
Range on Protein: 149-197
Range on HMM: 13-60/130.0
EGYINASHIRFDNASTDYILTQYPLPSTIRDFWKMVYVTKVtQVITIFE
. ||||| . . ...|.||| || | |||||. | |. ..
ntyinasfvGllgrtaeylltqhpladtsmdfwkmmleryv.nvlvvlg
|
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| subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 110-197 | 3.5e-06 | 21.4 | In-house | 13-100 (290) | alignment | ||
Range on Protein: 110-197
Range on HMM: 13-100/290.0
NEWEKNVNKNRTKDVKLIDATRVVLTNPEKsKMgpaddVEGYINASHIRFDNAsTDYILTQYPL-------PSTIRDFWKMVYVTKVTQVITIFE
.. |. .... .| |. |||||| . | .. ...|| |... . | |||| |. ||| .|| |. ||.||. . |
tdyvkkhemdqRlevpLveatrvvLkgygk.rf.....nddyiHAnrvtcpng.lrliltqsPqekitekrnStiekfwwmakqEkvkqvVmlce
|
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| subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 152-198 | 6.5e-06 | 20.1 | In-house | 78-124 (301) | alignment | ||
Range on Protein: 152-198
Range on HMM: 78-124/301.0
INASHIRFDNASTDYILTQYPLPSTIRDFWKMVYVTKVTQVITIFEP
| | | . . .| || ||..| ||| |. .| ... . .
ihanwiptsGhphrfiatqgPlkntsedfwamlvqydvekivmlgqk
|
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