Gene mtm-3 in Caenorhabditis elegans

Synonym: CELE_T24A11.1, mtm-3

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family Myotubularin
Subfamily MTMR3
Protein sequence
ID Type Fasta BLAST phosphatome Note
CeleP130_AA protein Get Run
CeleP130_AA_248-637 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_MTMR3_pd Subfamily MTMR3 358-632 2.8e-130 428.0 In-house 170-441 (442) alignment 
Range on Protein: 358-632
Range on HMM: 170-441/442.0
EEKKQFIIMDARGYTSAFANRARSGGFENTEYYQQAKLEFLGLPNIHAVRGSFNNVRTMLHNLGPNEQLLTSLQTTGWLLNLSNLLVNAANCADHLSK-G
||||...|.|||.||.||||||..||.|..|||......||||.|||||| |||..|..|..   . ..|..|..| || |||.|| .|........| |
eekkkllivdarsytaafanrakgGGceleeyypncevvflglanihavrksfnslrallsqspdesnwlsalektkWlqnlsvllkaavkvveavdkeg

HSVLVHCSDGWDRTTQVTTLAKIMLDEYYRTVKGFEELIRRDWIAFGHKLYDRqlVAFG-NWGTSDERSPVFLQFLEAVRHLQREQPTLFQFTHAYLIKL
..||||||||||||||...|||..||.||||..||..|..|.|..||||..||  ...| |.....||.|||||.|.||..|||..||.|.|..|.|.||
rpvlvhCsdGWdrttqivalakllldpyyrtleGfkvlvereWldfGhkfadr..cghgenvddanercPvflqwldavhqlqrqfPtsfefneaflvkl

AKHAYSGLFGSFLFNSHKERREamEKCKGTLVDIWRFIGPHNEEYVNQSFDEHyTGAVKPVNVSVINLRVWHEVFAD
..|.||.|||.||.||.|||.|  ||.| .....|... ....||.|....|. | ||. ..|||..|..|.||...
vqhtysclfGtflansekeree..ekvkertlsvWsllrakekeyrnllykek.teavllpavsvrelklwsevyle
Myotub-related Myotubularin-like phosphatase domain 224-577 8.4e-123 402.6 Pfam-A 4-352 (353) alignment
Myotub-related Myotubularin-like phosphatase domain 224-577 8.4e-123 402.6 In-house 4-352 (353) alignment
0040695 (Phosphotyrosine protein) phosphatases II 254-632 5.2e-117 384.7 In-house 12-384 (388) alignment 
Range on Protein: 254-632
Range on HMM: 12-384/388.0
ITHIDFNRLGMS-EHFQISSVNENFEVCPTYPEKIIVPKGITDDDIRKGAPYRSIGRFPAVIWRCRKTRAVLMRSSQPQVGILSWRNPTDEKIIEEAVKA
    ...|||.. ....||.||||.|.||.|| ...||| |.|..... | .|| ||.|....|.... |||.|||||.||.| .|.  |||..|. .|.
dilrelkrlglgldlwrisivNenyelcpsYPallvVPksisdellkrvarfrskgriPvlsyrhpnngavllRssqplvglllsrsledeklleailkl

SRiegeEKKQFIIMDARGYTSAFANRARSGGFENTEYYQQAKLEFLGLPNIHAVRGSFNNVRTMLHNLGPNEQLLTSLQTTGWLLNLSNLLVNAANCADH
 .    ......|.|.|....|.|||| .||.||...|..|.| ||..|||| || |..... .. |. .  .||..|. .|||  ....|  | .....
lp....nlskllivdlrpklnalanralgggvenedaypnaeliflnipnihvvreslqklldaclnvpdslnllslleesgwldliklilelavlivkl

LSKGHS-VLVHCSDGWDRTTQVTTLAKIMLDEYYRTVKGFEELIRRDWIAFGHKLYDRQLVaFGNWGTSDERSPVFLQFLEAVRHLQREQPTLFQFTHAY
|..|.| ||||||||||||.|.. || ..|| ||||..|| .|| ..|..||||..||  . . ..  |.|.|||||.||..| .|.|  || |.|.. .
ldlgnssvlvhcsdgwdrtsqlssLaqllldPyYRTleGFqvLiekeWlsfghkfadRlgh.leseidskefsPvFllFLdcvwqLlrqfPtaFeFnerl

LIKLAKHAYSGLFGSFLFNSHKERREAmeKCKGTLVDIWRFIGPHNEEYVNQSFDEHYTGaVKPVNVSVINLRVWHEVFAD
|. || |.||..||.|||||.|||.|.  ..   .. .|...  ...|..|...| . .  |  ...||..|..|.|.. .
LlfLadhlyscrfgtFlfnsekerlel..svsertlslwsyllsrkseflnplYdpssle.vllpslsvldlllWleyylr
subfamily_MTMR1_pd Subfamily MTMR1 258-631 2.5e-108 354.8 In-house 15-384 (389) alignment 
Range on Protein: 258-631
Range on HMM: 15-384/389.0
DFNRLGMSEH--FQISSVNENFEVCPTYPEKIIVPKGITDDDIRKGAPYRSIGRFPAVIWRCRKTRAVLMRSSQPQVGILSWRNPTDEKIIEEAVKASri
...|||. ..  ..|...|...|.|.|||....||| ..|.|..| | .|| ||.| . |  ....||..|.||| ||. . |.. |||.......|   
elerlgllneklWritklnkkyelcdtYpavlvvpkvvsdedlkkvaafrskgRlPvlswlnkenqavilrasqplvGlsgkrskedekylqailean..

egEEKKQFIIMDARGYTSAFANRARSGGFENTEYYQQAKLEFLGLPNIHAVRGSFNNVRTMLHNLGPNEQLLTSLQTTGWLLNLSNLLVNAANCADHLSK
  .......|.|||  ..|.||.|...| |..|.|..|.| || ..|||.|| |..... ..     ... |..|. | || ... .|  | . ......
..aqsekllildarssvnavankakgkgyeseeaYknaelifldihnihvvReslkklkelvlpnvddkkwlsalestkWlehiklilagavkivekvet

G-HSVLVHCSDGWDRTTQVTTLAKIMLDEYYRTVKGFEELIRRDWIAFGHKLYDRQLVAfGNWGTSDERSPVFLQFLEAVRHLQREQPTLFQFTHAYLIK
  .|||||||||||||.|.|.||...|| ||||..||| || ..|..||||. .|   . ..  . .|||||||||...|  |.|  || |.|.. .|| 
ektsvlvhcsdGWDRtaqltsLamlllDsyyRtieGfevliekeWlsfGHkfkeRlghg.dknssdaersPvFlqfiDcvwqltrqfptAFefneefLit

LAKHAYSGLFGSFLFNSHKERREAmeKCKGTLVDIWRFIGPHNEEYVNQSFDEHYTGAVKPVNVSVINLRVWHEVFA
|. | ||.|||.|||||.|||...  |.| . | .| ..  ..||..|. ..|. .  |  ...|. .|..|.| ..
lldhlysclfGtflfnsekervke..kvkektvslwsyvnsskeeftnplyaeelekkvlypkaslrrlelWkeyyl
subfamily_Dicty-MTMR1-like_pd Subfamily Dicty-MTMR1-like 258-608 1.2e-102 336.1 In-house 24-370 (404) alignment 
Range on Protein: 258-608
Range on HMM: 24-370/404.0
DFNRLGMSEH--FQISSVNENFEVCPTYPEKIIVPKGITDDDIRKGAPYRSIGRFPAVIWRCRKTRAVLMRSSQPQVGILSWRNPTDEKIIEEAVKASRI
...|||....  ..||..| ..|.|.|||. ..||. |.|... | | .|| ||.|.. || |.......|||||.||.   |   |||.|.   ||. .
EykRlgikseseWriskinsdyelcetYPkllvvPesisDeelkkvasfRskgRiPvlswrhrsknstitRssqplvGltksrseedEklinsirkaktq

EGeekkQFIIMDARGYTSAFANRARSGGFENTEYYQQAKLEFLGLPNIHAVRGSFNNVRTMLHNLGPN-EQLLTSLQTTGWLLNLSNLLVNAANCADHLS
      . .|.||| ...| ||.| . |.|... |.....|||.. ||| .| |..... . ..   . .. |. |. ..|| ....|| .... .... 
le....tlyildarpkanavansakgagyedisryenceieflnienihelreslkklkkavnsiiekeknwlselessrWldhiklllegskrivelie

-KGHSVLVHCSDGWDRTTQVTTLAKIMLDEYYRTVKGFEELIRRDWIAFGHKLYDRQLVafGNWGTSDERSPVFLQFLEAVRHLQREQPTLFQFTHAYLI
 ...|||||||||||||.|...|....|| ||||..||. || ..|. |||| ..|.     ..  ||||||.||||...| .| .  || |.| . .||
kekssvlvhcsdgwDrtsqlsslsqllldpyyrtiegFivliekewlsfGhkfaqRigq..ttekssdersPiflqFidcvyqltkqfptsFeFnekfli

KLAKHAYSGLFGSFLFNSHKERReaMEKCKGTLVDIWRFIGPHNEEYVNQSFDEH
|. .. ||. || ||..|.|||    .. .  .| .|  .  ...||.|. .  .
kildalyscrfgtFLydsekeRq..qnnlaketvslWalleankseylnplyile
subfamily_MTMR6_pd Subfamily MTMR6 257-631 4.7e-92 301.3 In-house 26-393 (397) alignment 
Range on Protein: 257-631
Range on HMM: 26-393/397.0
IDFNRLGMS-EHFQISSVNENFEVCPTYPEKIIVPKGITDDDIRKGAPYRSIGRFPAVIWRCRKTRAVLMRSSQPQVGILSwRNPTDEKIIEEAVKASri
 ...|.|.. |.......|...|.| |||... ||| .| . .   . .|| ||.| . . .....| . |.|||  |. . |   |||..|   ||   
aeytrmgvpnekwtltdlnkdyelcdtyprelyvPksatkevlvgsskfrskgrlPvlsylhkeneaaicrcsqplsgfsa.rcledeklleairkan..

egEEKKQFIIMDARGYTSAFANRARSGGFENTEYYQQAKLEFLGLPNIHAVRGSFNNVRTMLHNLGPNE-QLLTSLQTTGWLLNLSNLLVNAANCADHL-
   . . ....|.|    |.||.|   |.||.. |.  |..|.|. ||| .| | ...  . ..  ..  . |..|...|||  . ..|  ..  |  . 
..pnsellyvvdtrpklnalankaagkGyenednysnikfqfvgienihvmreslqkllevvelksksvseflsglessgwlkhikavldasifiakava

SKGHSVLVHCSDGWDRTTQVTTLAKIMLDEYYRTVKGFEELIRRDWIAFGHKLYDRQLVAfgnWGTSDERSPVFLQFLEAVRHLQREQPTLFQFTHAYLI
..|.|||||||||||||.||..||...||.||||.|||  || ..|..||||. .|.       . | | ||.|.||||.| .|.. .|. |.|  ..|.
eegasvlvhcsdGwdrtaqvcslasllldpyyrtikGflvliekewlsfGhkfsercGll...dedskevsPiftqflecvwqlleqfpkafefnerfll

KLAKHAYSGLFGSFLFNSHKERREAmeKCKGTLVDIWRFIGPHNEEYVNQSFDEHYTGAVKPVNVSVINLRVWHEVFA
.| .| ||  ||.|| |..|.||..  | |     .| ..  ....|.|  .... . .|  ..... .|..|. ...
elhdhvyscqfGtflgncekdrrdl..klkertkslwayllerkddylnplykaetekevlkpdtapaalklwralyn
subfamily_MTMR9_pd Subfamily MTMR9 259-630 1.5e-76 250.1 In-house 24-389 (393) alignment 
Range on Protein: 259-630
Range on HMM: 24-389/393.0
FNRL-GMSEHFQISSVNENFEVCPTYPEKIIVPKGITDDDIRKGAPYRSIGRFPAVIWRCRKTRAVLMRSSQPQVGILSWRNPTDEKIIEEAVKASrieg
|..|   |... |||||.||.||..|||..||||.|.|..... | .|. ||||   .. ..|.|||.||||| .|    |   |||... ..|..    
faklisasdewRissvNknfkvcasypesvivPkaiddeelkasaafreggrfPvLsylhketkavllrssqplcgssgkrckedekllnlvlkkl....

eekKQFIIMDARGYTSAFANRARSGGFENTEYYQQAKLEFLGLPNIHAVRGSFNNV-RTMLHNLGPNEQLLTSLQTTGWLLNLSNLLVNAANCADHLSK-
   |. .|.| |. ..| ..|.. ||.| .. |.| | .   | ... .  |. ..  .. ..   ... |  |...||| .. .||  |.. |. |.. 
...kkGlivdtrsksaaenarskgggietevkysqwkkasrslesvasiqdslaklleacsdaglstdkflsrleksgwlsqvadlleaalvvaqcldee

GHSVLVHCSDGWDRTTQVTTLAKIMLDEYYRTVKGFEELIRRDWIAFGHKLYDRQ-LVAFGNwGTSDERSPVFLQFLEAVRHLQREQPTLFQFTHAYLIK
| .|.|| ..| | | |||.||...|| ..|||.|||.|| |.||  ||    |.  ||. .  ......|||| ||..|  . .  |  | | . .|| 
gapvvvhgeeGlDatlqvtsLaqlildpdaRtvrgfealiereWiqaGHPFasRaskvaake.tkkklsgpvfllFLDcvyqilsqfpasFEFneelLil

LAKHAYSGLFGSFLFNSHKERREamEKCKGTLVDIWRFIGPHN--EEYVNQSFDEhyTGAVKPVNVSVINLRVWHEVF
| .|.||  ||.|| ....||.|  .| |   |..|...  ..  ....|  ...  .  |  ..|  . |..|.|..
lfehsyssqfgtflcdneaerke..lklkkktvslwsyvnrpeklkqflnplyea..naeviwpsvapqslelWsely
subfamily_Ank-MTMR1_pd Subfamily Ank-MTMR1 266-629 1.8e-69 226.4 In-house 40-400 (405) alignment 
Range on Protein: 266-629
Range on HMM: 40-400/405.0
EHFQISSVNENFEVCPTYPEKIIVPKGITDDDIRKGAPYRSIGRFPAVIWRCRKTRAVLMRSSQPQVGILSWRNPTDEKIIEEAVKASriegeEKKQFII
 .....|.| ....| .|.  ..| .  .| |. |   .|| || |.. |.  .. | . | ||| |||   | | ||    .   ..       | . .
cywkvtsinkeykmcssyssslvvlskaldkdlekifsfrskgripslswkdpssnasisrcsqplvgierarcpedelycsslalsa.....psktlyl

MDARGYTSAFANRARSGGFENTEYYQQAKLEFLGLPNIHAVRGSFNNVRTML--------HNLGPNEQLLTSLQTTGWLLNLSNLLVNAANCADHLSKGH
.|||    |.|| |   ||||   | ..|| |. .|||| .| |.... . .        |    . ..   .. |||.  .  .|  |.  |. . || 
idarpklnaiantangagfenihnypncklvfmnipnihvirksleklvlamkssardkdhtestdmrfwgyieetgwishiksileaatfsaelilkgn

SVLVHCSDGWDRTTQVTTLAKIMLDEYYRTVKGFEELIRRDWIAFGHKLYDRQLVAFgnwGTSDERSPVFLQFLEAVRHLQREQPTLFQFTHAYLIKLAK
|.||||||||||| |.|.|..|.|| ||||..||. || ..|..||||.  |        |  .||||.| |||... .|  . | ||.|| . |. .. 
silvhcsdgwdrtpqitsltqilldpyyrtivgfqvliekewlsfghkfslrlghlp...gneeerspifqqfldccfqllsqfpllfeftpslllfisd

HAYSGLFGSFLFNSHKERREAMEKCKgtLVDIWRFIGPHNEEYVNQSFDEHYTGAVKPVNVSViNLRVWHEV
  .|  .|.|| |  |.| .   | |   . ||  .    . ..|  .. .   ..||   |   | .|. .
nihsckygtflnncekdrvqdqvktk..tisiwsevnlnvnkflnpyynpqdiqsikpklysr.clelwkac
subfamily_MTMR3_pd Subfamily MTMR3 223-357 1.3e-50 165.5 In-house 3-133 (442) alignment 
Range on Protein: 223-357
Range on HMM: 3-133/442.0
FAWKFSEavDELDRDGklpsWLLRADSVAQEITHIDFNRLG--MSEHFQISSVNENFEVCPTYPEKIIVPKGITDDDIRKGAPYRSIGRFPAVIWRCRKT
.|||..|  .|..|||    .||||.|||.| ......|||  ..|...||.||..|..|..||.|.|||| |||||..|.|..||..|.|||.||..|.
hawklee..eekerdg....fllraasvaeeklkeeverlGfdlkeawrisdvnsdfklCssyPkklivPksitdddlkkvasfrslkrlPavvwrhkkn

RAVLMRSSQPQVGILSWRNPTDEKIIEEAVKASRIEG
.|||.|.|||.||.|.||| .|||......||. .. 
gavlarcsqPevgwlgWrnaedekllkaiakacalda
subfamily_MTMR10_pd Subfamily MTMR10 265-590 6.4e-42 135.7 In-house 23-317 (380) alignment 
Range on Protein: 265-590
Range on HMM: 23-317/380.0
SEHFQISSVNENFEVCPTYPEKIIVPKGITDDDIRKGAPYRSIGRFPAVIWRCRKTRAVLMRSSQPQVgilSWRNPTDEKIIEEAVKASRIEGeekkqfi
|. .  . .|| |....|.|....||. ..|.|...       .|||  .|   |..|.|. | . .    .  .. .|. ..| |...  .        
sdaivvllknelfaaaqtlPqyfvvpnslsdsdverlsrhykesRfplwvwshakgaallrlsalqea...esadkekeekmlelvrkchpan.......

imdargytsafanrarsggfenteyyqQAKL--EFLGLPNIHAVRGSFNNVRTMLHNLGPN------EQLLTSLQTTGWLLNLSNLLVNAANCADHL-SK
                           . ||      ||.|. |  .....| .  .  ..      .. |.||. |.||   . .|  | . .. . .|
...........................dvklvdlsdelpsiqdvqkaylklreLcvidtseefvtlddkwlssLektrWLayvrlclstasdavktvvek

GHSVLVHCSDGWDRTTQVTTLAKIMLDEYYRTVKGFEELIRRDWIAFGHKLYDRqlvaFGNWG-TSDERSPVFLQFLEAVRHLQREQPTLFQFTHAYLIK
..||..  |.| |    |  || .||| .||| .||..|| . |.| ||.  ||     |.    ....||||| ||. |  | .  |. |.||. .||.
krsvilqesegrDlscvvaSLaqlmldphyrtisGfqsliqkewvaaghpfldr....lghikpseksespvfllFldcvdqlleqfpseFeFtetfLia

LAKHAYSGLFGSFLFNSHKERREAMEKCKGTLVDIW
|  . .||.|..||||| ..| .|... .  |.. .
lwdsshsgifltflfnseeqrlkavvsssplliaks
subfamily_MTMR5_pd Subfamily MTMR5 388-627 3.3e-41 133.6 In-house 223-476 (483) alignment 
Range on Protein: 388-627
Range on HMM: 223-476/483.0
EYYQQAKLEFLGLPNIHAVRGSFNNVRTMLHNLGP----NEQ-LLTSLQTTGWLLNLSNLLVNAANCADHLS-KGHSVLVHCSDGWDRTTQVTTLAKIML
| ...| .  . |..| .|. ||. .. .     .    ..|  | |..   ||  .|.||  ..  .| |  .| ||||   |||| |.||..||...|
evdskaefipvelveirqvkasfkkllraClpstaveeaesqsFlksvedseWlqqissllqlsgavvdlldlqgssvlvslEdGwdvtaqvsslaqlll

DEYYRTVKGFEELIRRDWIAFGHKLYDRQLVAFGNWGTsdERSPVFLQFLEAVRHLQREQPTLFQFTHAYLIKLAKHAYSGLFGSFLFNSHKERREAME-
| ||||..||. |. ..|.||||.  .|      . ..    .|||||||..|  ..|  |. | | . ||  || |  |  |  ||..| .|| |.   
dpyYRtleGFkvLveKEWLafGHrFtkrsnqtlsaqss..gfaPvFlqFLDcvhqvsrqfPlafefndfylkflayhsvsnrfrtfllDseyerlesgll

-------KCKGTLVDIWRFIGPHNEE---YVNQSFDEHYTGAVKPVnVSVINLRVWH
       . | . . .| .|  ...    . |  .... . ...|  ..| .|.||.
yeekaekrakkagksvwdyidrqhkrspifynflyspdesevlrPs.snvsslkvWd
subfamily_MTMR5_pd Subfamily MTMR5 252-339 1.6e-20 65.3 In-house 7-106 (483) alignment 
Range on Protein: 252-339
Range on HMM: 7-106/483.0
QEITHIDFNRLGMS--------EHFQISSVNENFEVCPTYPEKIIVPKGITDDDIRKGAPYRSIGRFPAVIWRCRKTRAVLMRSSQPQ----VGILSWRN
.  . .|..|||.         ..|.||.||....|| .||  |.||. . || |.. |.    .|.|.|.|| ....|.|.||....    ||.|   |
erayvqdykRlGlgalngaskrgkfrisevNkkytvcrsYPalivvPsevsddsiarvakcfrqnRlPvvtWrhernkalLiRsggfeskgvvgllksan
subfamily_pats1_pd Subfamily pats1 392-506 2e-18 58.1 In-house 335-453 (691) alignment 
Range on Protein: 392-506
Range on HMM: 335-453/691.0
QAKLEFLGLPNIHAVRGSFNNVRTMLHNLGPNEQLLTSLQTTGWLLNLSNLLVNAANCADHLSKGHSVLVH-CSDGWDRTTQV---TTLAKIMLDEYYRT
 ....|| ||  . |.  |...   . .|. ...   ...   |. ..  ||  | . . .| .|.|||..  .|. . . ..   ..||....| .|||
ssniiflslPtrekveerffdllqsilsldgsddewkeieeskwvdsvkllleaavkvsnlldeGssvllknsidsPlieldlasisslaqvlsdPfyrt

VKGFEELIRRDWIAFGHKL
. ||  || ..|. .|. .
ldGfkvliekewlsyGfPf
FYVE FYVE zinc finger 820-883 6.3e-17 51.3 Pfam-A 8-68 (69) alignment 
Range on Protein: 820-883
Range on HMM: 8-68/69.0
ESGHCAYCKKEFNkLSvyveDRQHHCRNCGRVVCEDCSKNRFSVI--EEGKSVQKRACDSCYDSMH
|. .|  |.|.|. |.     |.||||.||.|||..||..|....  |.... . | |..|.....
eakkCeiCakkFs.lt....rrrhhCrlCGkvvCskCsskrvekleeesaeekevrvCkeCleels
subfamily_pats1_pd Subfamily pats1 524-602 7.2e-16 49.7 In-house 553-629 (691) alignment 
Range on Protein: 524-602
Range on HMM: 553-629/691.0
SPVFLQFLEAVRHLQREQPTLFQFTHAYLIKLAKHAYSGLFGSFLFNSHKERREAmeKCKGTLVDIWRFIGPHNEEYVN
||.|.|||..|  ||.| |. |.|   .|. | |...|. ||.||..  |.. |   |       || ||   .  ..|
sPifvqfldlvwqlqkefPfhfefneslllllvkesfssrfGnflyseakrdser..kvlkrsksiwsfinqnksrfin
PTPc_DSPc_SM00012 394-559 2.5e-12 42.3 In-house 4-104 (105) alignment 
Range on Protein: 394-559
Range on HMM: 4-104/105.0
KLEFLGLPNIHAVRGSfNNVRTMLHNLGPNEQLLTSlqttgwllnlsnllvnaancadhlskGHSVLVHCSDGWDRTTQVTTLAKIMLDEYYRTvkgfee
.....| |. .. . | ... ..|...  |..  .|                          ...|.||||.|..|| ....|. .. . ...|      
hyhytgwpdhgvPees.dsilellravkknknkses..........................skpvvVhCsaGvgRtgtfvaldillqqleket......

lirrdwiafghklydrqlvafgnwgtsderspVFLQFLEAVRHLQREQPTLFQFTHAYLIKLAKHA
                                 ...... |..| ...|...|. . ||. .. ..
................................kevdifqivkelrkqRpgmvqteeqylflyrall
0051429 (Phosphotyrosine protein) phosphatases II 430-497 1.6e-06 23.5 In-house 125-199 (272) alignment 
Range on Protein: 430-497
Range on HMM: 125-199/272.0
LQTTGWLLNLS--NLLVNAANCADHlskGHSVLVHCSDGWDRTTQVTTLAKIMLD--------EYYRTVKGFEELIRR
|. |.|.      . |... .   .   |. |||||| |.|||  |  |  ..|.        .| .|  . || ...
lhytdwpdhgvpqeallellellld...ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlyleeavee
Zn-ribbon_8 Zinc ribbon domain 823-850 2.9e-06 13.7 Pfam-A 7-34 (42) alignment 
Range on Protein: 823-850
Range on HMM: 7-34/42.0
HCAYCKKEFNKLSVYVEDRQHHCRNCGR
.| .|.|||..|  . .| .  | .||.
rCekCgkefevlqsisdddeteCPeCgs
subfamily_MTMR14_pd Subfamily MTMR14 457-509 8.5e-06 16.8 In-house 269-327 (357) alignment 
Range on Protein: 457-509
Range on HMM: 269-327/357.0
HSVLVHCSDGWDRTTQVTTLAKIMLD---EYYRTVKGFEEL---IRRDWIAFGHKLYDR
  .||||  |||||   ..| .. |    . .....  | |   .  ||  |||.| ||
sGllvhcisGWdrtPlfvsllrlslWadglihqslsaaellyltvaydWflfghqlpdr