Synonym: CELE_R155.3, R155.3
Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
| Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
|---|---|---|---|---|---|---|---|---|---|
| subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 802-1109 | 4.7e-132 | 434.5 | In-house | 13-290 (290) | alignment | ||
Range on Protein: 802-1109
Range on HMM: 13-290/290.0
REALKSEQMKQRLPIPLVMDTRVVLKDYGTLFNDDYIHANRVTCSHGLQLILSQAPQEANGESCESTIESYWWTAKQEKSTQLVMMCDFDEKCPGKTN-S
. .|...|.|||..|||..||||||.||. |||||||||||||..||.|||.|.|||...|...||||..||.|||||..|.||.|.|.||...... .
tdyvkkhemdqRlevpLveatrvvLkgygkrfnddyiHAnrvtcpnglrliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfa
CARYYPESVGESMKFKNLTVECKSKIAEKDFETRELEVKFDGHEPHTVTHSRLVGWNPLNVQPDTLLFTSLIQKIKNSTTPVMVHCIDGISRSAAFASMI
||.|.||||||..|||.|||.||||..|.|.|||||.||||..|..|||||.|.|||.||||.||....|||||.|.|.|||.|||.||||||||.|..|
CakYvpesvgeelkfkgltvkCkskekeddvetRelvvkfddeeeftvtHsllkgWnklnvqedtktllsliqkvkasktpvivHcvdGiSrsAalaaii
IGYQLVIQSLGSVKLEAVVSYIRSQRAMAITSALELAFVDAGIVkllglfvdaqqnkgeltreqcILAQQELMRFYTSCPEaqkwfswpqkQQAKTGEKR
.|||..... ||||||.|....|.|||.|||||||||||||||| .||...|..|.....| ..||..||.
lgyQkiaetsgsvkledvlkalrkqralaitsalelafvdagiv.....................llaievldqfaeeete..........kkakaeeke
TYKKIKQLK
|||||||||
tykkikqlk
|
|||||||||
| 0040438 | (Phosphotyrosine protein) phosphatases II | 809-1108 | 2.4e-51 | 170.3 | In-house | 45-311 (317) | alignment | ||
Range on Protein: 809-1108
Range on HMM: 45-311/317.0
QMKQRLPIPLVMDTRVVLKDYGTLFNDDYIHANRVTCSH-GLQLILSQAPQeangescESTIESYWWTAKQEKSTQLVMMCDFDEkcpGKTNSCARYYPE
.. . |.. ..||.|...| ...|||.|. |.. . . . |. |.|. ..|.|..|. .....| .||.....| . . ||.|.|.
dknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPl.......pntvedFwrmvweqgvtvivmLtelee...lgrekcaqYwpl
svGESMKFKNLTVECKSKIAEKDFETRELEVKF-DGHEPHTVTHSRLVGWNPLNVQPDTLLFTSLIQKIKNS----TTPVMVHCIDGISRSAAFASMIIG
||.......||...| . ..... |.|||. .. |..|||| || .| |.. |. ......... .||.||| .|..|...|. . .
..getltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavrealedpggpvlVHCsaGvgRtGtfiaaylm
YQLVIQSLgSVKLEAVVSYIRSQRAMAITSALELAFVdagivkllglfvdaqqnkgeltreqcILAQQELMRFYTSCPEAQKWFSWPQKQQAKTGEKRTY
.... . | .| .| ..|.||..|... . |. . | .|..... ...|........|.... .. .
leqlekeg.gvdveeavkelreqRpgavqtpeqyrfl..........................ydalleylkrkltlepaselklkllklliplalddvk
KKIKQL
|.|.|
lkekel
|
|||||||||
| DSPc_SM00195 | 804-1045 | 2.5e-49 | 163.3 | In-house | 23-260 (263) | alignment | |||
Range on Protein: 804-1045
Range on HMM: 23-260/263.0
ALKSEQMKQRLPIPLVMDTRVVLKDYGTLFNDDYIHANRVTCS-HGLQLILSQAPQeangescESTIESYWWTAKQEKSTQLVMMCDFDEKcpgKTNSCA
|...... |.....||| ||. . ..|||.|| .... . . |. |.|. .||.|..|.. .||... ||.....|. . . |.
kkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPl.......pstvedFWrmvweekvkiivmlteeeen...gkekcd
RYYPESVGESMKFKNLTVECKSKIAEK-DFETRELEVKFDG-HEPHTVTHSRLVGWNPLNVQPDTLLFTSLIQKIKNS----TTPVMVHCIDGISRSAAF
||.||. |....|....|...... .| ....|.||....| .|...||. .|. .|. .| ...|....|.| ..|..||| .|..|...|
rywpeesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivVhCsaGvgRtgtf
ASMIIGYQLVIQSLGsVKLEAVVSYIRSQRAMAITSALELAFVDAGIVK
... | .. . . |.....|. .|.||...... ...|. |..
vtidiilskleeekk.vdifeivkelRkqRpgmvqtleqYlfiyeaile
|
|||||||||
| PTPc_SM00194 | 804-1045 | 2.5e-49 | 163.3 | In-house | 23-260 (263) | alignment | |||
Range on Protein: 804-1045
Range on HMM: 23-260/263.0
ALKSEQMKQRLPIPLVMDTRVVLKDYGTLFNDDYIHANRVTCS-HGLQLILSQAPQeangescESTIESYWWTAKQEKSTQLVMMCDFDEKcpgKTNSCA
|...... |.....||| ||. . ..|||.|| .... . . |. |.|. .||.|..|.. .||... ||.....|. . . |.
kkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPl.......pstvedFWrmvweekvkiivmlteeeen...gkekcd
RYYPESVGESMKFKNLTVECKSKIAEK-DFETRELEVKFDG-HEPHTVTHSRLVGWNPLNVQPDTLLFTSLIQKIKNS----TTPVMVHCIDGISRSAAF
||.||. |....|....|...... .| ....|.||....| .|...||. .|. .|. .| ...|....|.| ..|..||| .|..|...|
rywpeesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivVhCsaGvgRtgtf
ASMIIGYQLVIQSLGsVKLEAVVSYIRSQRAMAITSALELAFVDAGIVK
... | .. . . |.....|. .|.||...... ...|. |..
vtidiilskleeekk.vdifeivkelRkqRpgmvqtleqYlfiyeaile
|
|||||||||
| 0036941 | (Phosphotyrosine protein) phosphatases II | 810-1040 | 2.1e-47 | 157.2 | In-house | 42-270 (297) | alignment | ||
Range on Protein: 810-1040
Range on HMM: 42-270/297.0
MKQRLPIPLVMDTRVVLKDygtlFNDDYIHANRVTCSH-GLQLILSQAPQEangesceSTIESYWWTAKQEKSTQLVMMCDFDEKcpgKTNSCARYYPES
. . |. .|||.|.| ..|||.|. |.. . . . |. |.|.. .|.|..|. ....| .||.....|. . ||.|.|.
knRykdilpydhtRVkldd....egsdYinAsyvdgydlkrkfIatqgPlp.......ntvedFWrmvweqnvtvIvmltelvel...grekcaqywple
VGESMKFKNLTVECKSKIA--EKDFETRELEVKF-DGHEPHTVTHSRLVGWNPLNVQPDTLLFTSLIQKIKN------STTPVMVHCIDGISRSAAFASM
.|||......||...| ..|. .|.|||.. .. |..|||| || .| ... . ..|..... | .||.||| .|..||..|. .
egesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrkvlkllpsggpvlVHCsaGvgRsgtfiaa
IIGYQLVIQ--SLGSVKLEAVVSYIRSQRAMAITSALELAFVD
. .|.. . | | . .| ..|.||..|... . |.
dlmlqqledklkeggvdileavkklReqRpgavqtleqyrfly
|
|||||||||
| Y_phosphatase | Protein-tyrosine phosphatase | 811-1043 | 1.3e-46 | 154.2 | Pfam-A | 4-233 (235) | alignment | ||
Range on Protein: 811-1043
Range on HMM: 4-233/235.0
KQRLPIPLVMD-TRVVLKDYGTLFNddYIHANRV-TCSHGLQLILSQAPqeangesCESTIESYWWTAKQEKSTQLVMMCDFDEKcpgKTNSCARYYPES
|.| . |..| ||| ||.... . ||.|| | . .. ..|..|.| ..||||..|. |||.. .||... .|| . . ||.|.||.
knRykdilpydktrvklkgsegpsd..YInAnyvkgykekkkfIatQgP.......lkstiedFWrmvwqekvkvivmltsleek...grekcaqYwpee
VGESMKFKNLTVECK--SKIAEKDFETRELEVKFDGHEP--HTVTHSRLVGWNPLNVQPDTLLFTSLIQKIKNST----TPVMVHCIDGISRSAAFASMI
.||.......||.| .| .||.. .|.||.| ...| ..|.. . .|. .|. .. ...||.|...|. .||.|||..|..|.. |...
eeesltygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvald
IGYQLVIQSLGsVKLEAVVSYIRSQRAMAITSALELAFVDAGI
| . . . |.. .|. .|.||.....|. ...|. . |
illeqleaeee.vdvlqivkelRkqRpgmvqsleqYiflykai
|
|||||||||
| Y_phosphatase | Protein-tyrosine phosphatase | 811-1043 | 1.3e-46 | 154.2 | In-house | 4-233 (235) | alignment | ||
Range on Protein: 811-1043
Range on HMM: 4-233/235.0
KQRLPIPLVMD-TRVVLKDYGTLFNddYIHANRV-TCSHGLQLILSQAPqeangesCESTIESYWWTAKQEKSTQLVMMCDFDEKcpgKTNSCARYYPES
|.| . |..| ||| ||.... . ||.|| | . .. ..|..|.| ..||||..|. |||.. .||... .|| . . ||.|.||.
knRykdilpydktrvklkgsegpsd..YInAnyvkgykekkkfIatQgP.......lkstiedFWrmvwqekvkvivmltsleek...grekcaqYwpee
VGESMKFKNLTVECK--SKIAEKDFETRELEVKFDGHEP--HTVTHSRLVGWNPLNVQPDTLLFTSLIQKIKNST----TPVMVHCIDGISRSAAFASMI
.||.......||.| .| .||.. .|.||.| ...| ..|.. . .|. .|. .. ...||.|...|. .||.|||..|..|.. |...
eeesltygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvald
IGYQLVIQSLGsVKLEAVVSYIRSQRAMAITSALELAFVDAGI
| . . . |.. .|. .|.||.....|. ...|. . |
illeqleaeee.vdvlqivkelRkqRpgmvqsleqYiflykai
|
|||||||||
| 0050432 | (Phosphotyrosine protein) phosphatases II | 812-1040 | 1.3e-44 | 148.1 | In-house | 73-292 (308) | alignment | ||
Range on Protein: 812-1040
Range on HMM: 73-292/308.0
QRLPIPLVMDTRVVLkdyGtlFNDDYIHANRVTCS---HGLQLILSQAPQeangescESTIESYWWTAKQEKSTQLVMMCDFDEkcpGKTNSCARYYPES
. |. .||.| . ..|||.|. |.. . . |. |.| ..|.|..|. ..... ||.....| . . ||.|.|..
rykdilpydhsRVkl...d..egsdYInAsyvdgyssklprkfIatqgPl.......pntvedFwrmvweqnvrvIvmLtklve...ngrekcaqYwple
VG-ESMKFKNLTVECKSKIAEKDFETRELEVKF-DGHEPHTVTHSRLVGWNPLNVQPDTLLFTSLIQKIKNS--TTPVMVHCIDGISRSAAFASMIIGYQ
.| .|......||...| ..|. .|.||... .. | .|||| .| .| |.. . ........| |..||| .|..|...|. . . ..
lgggsleygkftvtllseevlddytvrtleltnlgdgesrtvthfhytnWpdhgvPpspeilldflelvrkslpggpivVHCsaGvGRtGtfialdllle
LVIQSlGSVKLEAVVSYIRSQRAMAITSALELAFVD
.. . | | .. .| ..|.||...... . |.
qleke.ggvdvfeavkklReqRpgmvqtpeqylfly
|
|||||||||
| 0039614 | (Phosphotyrosine protein) phosphatases II | 813-1041 | 4.2e-44 | 146.6 | In-house | 62-283 (297) | alignment | ||
Range on Protein: 813-1041
Range on HMM: 62-283/297.0
RLPIPLVMDTRVVLKDYGTL-FNDDYIHANRVTCSH--GLQLILSQAPQEAngescesTIESYWWTAKQEKSTQLVMMCDFDEKCPgKtnsCARYYPESV
|. ..||.||... ...|||.|. |.. . . . |..|.|.. |.|..|. .....| .||.....|. | ||.|.||..
ykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIatqgPlpe.......tvedFwrmvweqgvtvivmLtklvelgr.k...caqywpeeg
GesmKFKNLTVECKSKIAEKDFETRELEVKFdGHEPHTVTHSRLVGWNPLNVQPDTLLFTSLIQKIKN------STTPVMVHCIDGISRSAAFASMIIGY
| .....||.... . .... .|.|||. . |..|||| .|| .| |.. |. ........ . .|| ||| .|..|...|. . . .
g...tygdftvtllkvehldgytvrtlevtn.ngesrtvthfqytgwpdhgvppslellleflelvrealaelpkggpvlVHCsaGvgRtGtfiaaylml
QLViQSLGSVKLEAVVSYIRSQRAMAITSALELAFVDA
... .. | | .. .|...|.|| .|... . |.
eql.ekeggvdvleavkelreqRpgavqtpsqyrflyd
|
|||||||||
| 0043336 | (Phosphotyrosine protein) phosphatases II | 811-1039 | 9e-44 | 145.4 | In-house | 49-269 (278) | alignment | ||
Range on Protein: 811-1039
Range on HMM: 49-269/278.0
KQRLPIPLVMDTRVVLKDYGTLFNDDYIHANRVTCSH-GLQLILSQAPQEAngescesTIESYWWTAKQEKSTQLVMMCDFDEkcpGKTNSCARYYPesv
. |.. .||.|...| ...|||.|. |.. . . . |..|.|.. |.| .|. .....| .||.....| . . ||.|.|
nrykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpe.......tvedFwrmvwelgvttivmLtelve...lgrvkcaqYwp...
GESMKFKNLTVECKSKIAEKDFETRELEVKF-DGHEPHTVTHSRLVGWNPLNVQPDTLLFTSLIQKIKN----STTPVMVHCIDGISRSAAFASMIIGYQ
|.|......||.... . ..|. .| |||. .|..|||| .|| .| ... |. ........ | .||.||| .|..|...|. . . ..
ggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldflkavrealedsngpvlVHCsaGvgRTGtfialyllle
LViQSLGSVKLEAVVSYIRSQRAMAITSALELAFV
.. .. | | || .|...|.||..|... . |.
ql.ekeggvdleeavkelreqRpgavqtpsqyrfl
|
|||||||||
| 0045450 | (Phosphotyrosine protein) phosphatases II | 808-1039 | 1.6e-43 | 145.0 | In-house | 56-296 (307) | alignment | ||
Range on Protein: 808-1039
Range on HMM: 56-296/307.0
EQMKQRLPIPLVMDTRVVLKDYGTL-FNDDYIHANRVTCS---------HGLQLILSQAPQEAngescesTIESYWWTAKQEKSTQLVMMCDFDEKcpgK
. . |.. .|||.|.... ..|||.|. |.. .... |. |.|.. |.|..|. .....| .||.....|. .
kdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydlkrkfIatqgPlpe.......tvedFwrmlweqgvtvivmltelvel...g
TNSCARYYPESvGESMKFKNLTVECKSKIAEKDFETRELEVKF--DGHEPHTVTHSRLVGWNPLNVQPDTLLFTSLIQKIKN------STTPVMVHCIDG
. ||.|.|.. ||.. ..|.||...|. .... | |||. .|..|||| || .| |.. . ..|..... . .||.||| .|
rekcaqywPde.geeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfeelldfieevrkaleelpkggpvlVHCsaG
ISRSAAFASMIIGYQLVIQSLGS--VKLEAVVSYIRSQRAMAITSALELAFV
..|...|. . . .... . | |. .|...|.|| |... . |.
vgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrfl
|
|||||||||
| 0051299 | (Phosphotyrosine protein) phosphatases II | 815-1039 | 1.7e-43 | 144.5 | In-house | 57-278 (288) | alignment | ||
Range on Protein: 815-1039
Range on HMM: 57-278/288.0
PIPLVMDTRVVLKDYGTLFNDDYIHANRVTC-SHGLQLILSQAPQEangesceSTIESYWWTAKQEKSTQLVMMCDFDEkcpGKTNSCARYYPEsvGESM
|. ..||.|.... ..|||.|. ... .. . |. |.| . .|.|..|. ..... ||.....| . . ||.|.|. |.|.
dilpydhsRVkLsvldgvegsdYinAsyidgynlkrkfIatqgPlp.......ntvedFWrmvweqnvrvIvmltklve...lgrekcaqYwpl..ggsl
KFKNLTVECKSKIAEKDFETRELEVKF-----DGHEPHTVTHSRLVGWNPLNVQPDTLLFTSLIQKIKNS----TTPVMVHCIDGISRSAAFASMIIGYQ
.....||...| ..|. .|.|||. ..|..|||| .| .| ... |. ......... ||.||| .|..|...|. . . ..
tygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdspellldflrlvrkalasgggpvvVHCsaGvgRtgtfialdllle
LVIQSlGSVKLEAVVSYIRSQRAMAITSALELAFV
.. . | | .. .| ..|.|| ..... . ||
qleke.ggvdvleavkrlreqRpgmvqtpeqyrfv
|
|||||||||
| 0047943 | (Phosphotyrosine protein) phosphatases II | 812-1039 | 3e-43 | 143.6 | In-house | 43-264 (273) | alignment | ||
Range on Protein: 812-1039
Range on HMM: 43-264/273.0
QRLPIPLVMDTRVVLkdygTLFNDDYIHANRVTC-SHGLQLILSQAPQeangescESTIESYWWTAKQEKSTQLVMMCDFDEkcpGKTNSCARYYPESVG
. |. . ..||.| . ..|||.|. |.. .. . |. |.| ..|.|..|. ...... .||.....| . . ||.|.|...|
rykdilpydhsrvkl....gdggsdyinAsyvdgynlkrkfiatqgPl.......pntvedfwrmvweqnvrviVmLtelve...lgrekcaqYwplegg
E-SMKFKNLTVECKSKIAEKDFETRELEVKF-DGHEPHTVTHSRLVGWNPLNVQPDTLLFTSLIQKIKN------STTPVMVHCIDGISRSAAFASMIIG
| |......||...| ..|. .|.||... . .|..|||| || .| |.. . ..|..... | .||.||| .|..|...|. . .
elsltygkftvtllseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvrkalealpsngpvvVHCsaGvgRtgtfialdll
YQLVIQSlGSVKLEAVVSYIRSQRAMAITSALELAFV
..... | | .. .| ..|||| ..... . |.
ldqleke.ggvdvleavkllrsqRpgmvqtpeqyrfl
|
|||||||||
| 0040439 | (Phosphotyrosine protein) phosphatases II | 810-1038 | 1.8e-42 | 141.1 | In-house | 14-237 (249) | alignment | ||
Range on Protein: 810-1038
Range on HMM: 14-237/249.0
MKQRLPIPLVMDTRVVLKDYGTLFNDDYIHANRVTCSH-GLQLILSQAPQEAngescesTIESYWWTAKQEKSTQLVMMCDFDEKcpgKTNSCARYYPEs
. . |. .||.|.... || .|||.|. ..... . ..|. |.| . |.|..|. .....| .||.....|. . . ||.|.|.
knrypdilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpe.......tvedfwrmlwelgitvivmLtslvel...grekcaqywpl.
vGESMKFKNLTVECKSKIAEKDFETRELEVKF-DGHEPHTVTHSRLVGWNPLNVQPDTLLFTSLIQKIKN------STTPVMVHCIDGISRSAAFASMII
|.|......||...| . ..|. .|.||... |..||.| . ..| .| |.. . ..|..... . .||.||| .|..|...|. . .
.ggsleygdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaayl
GYQLVIQSLGsVKLEAVVSYIRSQRAMAITSALELAF
.... || | || .|...|||| .|... . |
mleqlekelg.vdleeavkllrsqRpgavqnpeqyrf
|
|||||||||
| 0046845 | (Phosphotyrosine protein) phosphatases II | 813-1039 | 6.9e-42 | 139.2 | In-house | 34-266 (284) | alignment | ||
Range on Protein: 813-1039
Range on HMM: 34-266/284.0
RLPIPLVMDTRVVLKDYGTL-FNDDYIHANRVTC------SHGLQLILSQAPQeangescESTIESYWWTAKQEKSTQLVMMCDFDEkcpGKTNSCARYY
|. ..||.|| .. ..|||.|. |.. . . |. |.| ..|.|..|. ..... .||.....| . . ||.|.
ykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPl.......pntvedFwrmvweqnvrvIVmltelve...ngrekcaqYw
PESvGESMKFKNLTVECKSKIAEKDFETRELEVKFD--GHEPHTVTHSRLVGWNPLNVQPDTLLFTSLIQKIKNS------TTPVMVHCIDGISRSAAFA
|.. ||.......||...|. ..|. .|.||... . |..|||| .| .| |.. . ......... |..||| .|..|...|.
ple.gevltygdftvtllseevkddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrellenlpgggpivVHCsaGvgRtGtfi
SMIIGYQLVIQSLG--SVKLEAVVSYIRSQRAMAITSALELAFV
. . ...... | .. .|...|.|| ..... . ||
aldllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfv
|
|||||||||
| 0042113 | (Phosphotyrosine protein) phosphatases II | 812-1038 | 9.7e-42 | 138.4 | In-house | 14-234 (245) | alignment | ||
Range on Protein: 812-1038
Range on HMM: 14-234/245.0
QRLPIPLVMDTRVVLKDYGTLFNDDYIHANRVTCSH-GLQLILSQAPQEAngescesTIESYWWTAKQEKSTQLVMMCDFDEkcpGKTNSCARYYPEsvG
. .|.. .|||.|...|. . .|||.|. |.... ..|..|.|.. |.| .|. .....| .||.....| . . ||.|.|. |
rysdilpydhtrvklspdggdldsdyinasyvdgyritpkfiatqgPlpe.......tvedfwrmlwelgittivmLteeee...lgrvkcaqywpl..g
ESMKFKNLTVECKSKIAEKDFETRELEVKF-DGHEPHTVTHSRLVGWNPLNVQPDTLLFTSLIQKIKN-----STTPVMVHCIDGISRSAAFASMIIGYQ
||......||...| ..|. .|.|||. .|...|.| . ..| .| ... |. .... ... | .||.||| .|..|...|. . . ..
esltygdftvtllseehlddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmle
LViQSLGSVKLEAVVSYIRSQRAMAITSALELAF
.. .... | || .| ..|||| .|... . |
ql.ekelgvsleeavkelrsqRpgavqtpsqyrf
|
|||||||||
| 0045098 | (Phosphotyrosine protein) phosphatases II | 816-1036 | 8.3e-35 | 115.9 | In-house | 42-261 (278) | alignment | ||
Range on Protein: 816-1036
Range on HMM: 42-261/278.0
IPLVMDTRVVlkdygtlfndDYIHANRVTCShGLQLILSQAPQEangesceSTIESYWWTAKQEKSTQLVMMCDFDEKcpgKTNSCARYYPEsvGESMKF
|. . .||. |||.|. ... . . |. |.| . ||....| . .....| .||.... |. . . ||.|.|| |.|. .
ilpydhsrVk..........dYINAsyidgy.pkkfIatqgPlp.......stvadfwrmlwelgitvivmltelvel...grekcaqywpe..ggslty
KNLTVECKSKIAEKDFETRELEVKF-----DGHEPHTVTHSRLVGWNPLNVQPDT--LLFTSLIQKIKN-----------------STTPVMVHCIDGIS
...||...| .|. .| |.| . |...||| ...| .| ... | .|.. |.. | .|| ||| |..
gdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvlVHCsaGvg
RSAAFASMIIGYQLViqSlGSVKLEAVVSYIRSQRAM-AITSALEL
|..... . . ..|. | | |. .|...|||| . |... .
RtGtlvaaylmlell..e.ggvdlleavkelrsqRpglavqnleqy
|
|||||||||
| 0037934 | (Phosphotyrosine protein) phosphatases II | 817-1033 | 2.1e-30 | 101.5 | In-house | 20-228 (243) | alignment | ||
Range on Protein: 817-1033
Range on HMM: 20-228/243.0
PLVMDTRVVLKDygtlfnDDYIHANRVTCSHglQLILSQAPQEAngeSCESTIESYWWTAKQEKSTQLVMMCDFDEKcpgKTNSCARYYPesvgESMKFK
.. ..||.|.. .|||.|| ... .||..|.| . ..|.. .|.| .....| .||.....|. . . ||.|.| ... ..
lpydhsrvkleg......sdyinanliyvtp..rliatqgPlpe...tveddlasfwrmlwelgitvivmltelvEl...grekcaqywp....gevtyg
NLTVECKSKIAEKDFETRELEVKF--DGHEPHTVTHSRLVGWNPLNVQPDTLLFTSLIQKIK------------NSTTPVMVHCIDGISRSAAFASMIIG
..||...| .|. |.|... ......|.| ..| .| ... . ....... .| || ||| |..|..... . .
dftvtllseehlddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtliaaylm
YQLViqslgSVKLEAVVSYIRSQRAM-AITSA
..|. .| || .| ..|.|| . |...
llll.....gvdleeavkllreqRpgkavqtp
|
|||||||||
| subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 862-1064 | 7.9e-30 | 98.8 | In-house | 33-237 (255) | alignment | ||
Range on Protein: 862-1064
Range on HMM: 33-237/255.0
GESCES-TIESYWWTAKQEKSTQLVMMCDFDEkcpGKTNSCARYYPESVGESMKFKNLTVECKSKIAEKDFETRELEVKFD-GHEPHTVTHSRLVGWNPL
. .| |.. .. | .| |....||.||| | . . | .|.| | .|.....| . .|. . |.|. .. . |||.| ||
rknlysltvdkfyqtivqtktevvvmlcdfae...egvekcssyfplekdeklkladvnvtttkssadvvlrtleitstlgekkkthtvkhysykGWiek
NVQPDTLLFTSLIQKIKNStTPVMVHCIDGISRSAAFASMIIGYQLVIQSLG-----SVKLEAVVSYIRSQRAMAITSALELAFVdagIVKLLGLFVDAQ
| .. ... ...| .|.||| || |||||. . . || .|.|| . .. .||.|. || |.||| |. .| |. ..
naPelareilnilkvvrds.ksvvvhCstGiGrsaafvlaelvyqkmirsldttetveldylslleelrskrkraihtPlqlafs...ilmvldlvfpkg
QNKGELT--REQ
. . ... |.
eleakyqeirks
|
|||||||||
| subfamily_hpo-7_pd | Subfamily hpo-7 | 866-1061 | 1.5e-27 | 91.2 | In-house | 44-237 (263) | alignment | ||
Range on Protein: 866-1061
Range on HMM: 44-237/263.0
ESTIESYWWTAKQEKSTQLVMMCDFDEkcpGKTNSCARYYPESVGESMKFKNLTVECKSKIAEKDFETRELEVKFD-GHEPHTVTHSRLVGWNPLNVQPD
||.... | .| |....||.||| | . | .|.| | .|..|..| . . . |.|| .. . |||.| .|| | .
vqtidkfyqtivqtktevvvmLcDfne...egvekcssyfPlekdekqklanvnvcttkvqsdvllktlellstlgeKkkthtvkhysykgWiekndpel
TLLFTSLIQKIKNStTPVMVHCIDGISRSAAFASMIIGYQLVIQSLG-----SVKLEAVVSYIRSQRAMAITSALELAFvdaGIVKLLGLFVDAQqNKGE
. ... .|| ...||| || |||||. . . || .|.|| . .. .||.|. || . ||| |. .| ..... |||
areilnilkvarns.kslvvhcstGiGrsaafsvaElvyqkmirsldttstveldylsLleelrssrkraihtPmqLaf...silmvLdfvlnnf.akge
LT
|
le
|
|||||||||
| subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 804-1035 | 1.4e-26 | 88.4 | In-house | 44-271 (305) | alignment | ||
Range on Protein: 804-1035
Range on HMM: 44-271/305.0
ALKSEQMKQRLPIpLVMDTRVVLKDYGTLFNDDYIHANRVTCSHG-LQLILSQAPqeangesCESTIESYWWTAKQEKSTQLVMMCDFDEkcpGKTNSCA
. .. ... .. | | |. |. .| . ||| |. | .. . |..|.| ..|.. .| . .|| ...||... | |. . |
eankaknrlkeit.lldddriiltekeslddsdyinasyvdgykrkkkyivaqgP.......lkntvadfWrliveekvstivmltklve...ggkdkCr
RYYPESVGESMKFKNLTVECKSKIAEKDFETRELEVKF--DGHEPHTVTHSRLVGWNPLNVQPDTLLFTSLIQKIKNS-----TTPVMVHCIDGISRSAA
.|.|||..|...| ...|| ||. . .|. .|.|.. . . .| .||.. .| | | . . |||...... .|..||| .|..|. .
qYWpesktekkefgefsvelksektasdyieRklkisiededkesrtvlqyqltdWPdhGvpqfatsllslikrvqkdqkkdkgvpllVhCsagvgRtGv
FASMIIGYQLVIQSlGSVKLEAVVSYIRSQRAMAITSALE
| .. | . . . ..| . |. .||.| .... .
fiavdialerlkkE.evvdvfevlkqlRskrmkmvqtldq
|
|||||||||
| subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 821-1031 | 6.7e-26 | 85.6 | In-house | 70-267 (290) | alignment | ||
Range on Protein: 821-1031
Range on HMM: 70-267/290.0
DTRVVLKDYGtlfNDDYIHANRVTCSHGlQLILSQAPQEAngescesTIESYWWTAKQEKSTQLVMMCDFDEKcpGKTnSCARYYPESVGESMKFKNLTV
|||.||| . . ||.||| | . .||.| . .. |. .| ||| . .||.|. |. ||. |..|||| || . | ..||
ktrvilkdGy...dGdyvhanyvkGlka.mfiltqGalkd.......tvidiwrmvlqekvaaivmlcelied..Gka.kceqyypekeGevltfGeitv
ECKSK-IAEKDFETRELEVK-FDGHEPHTVTHSRLVGWNPLNVQPDTLLFTSLIQKIKNSTTPVMVHCIDGISRSAAFASMIIGYQLVIQSlGSVKLEAV
| . ... . | |. | | . | ... | | || . ... ... . ||.||| || |. .|... .| |.... ...| .
lcseeddkdaniikktlsvrdkdsGkehklkhlkikswpdksvalstlallrtlrilrkasGpvvvhcsaGiGrtGtfvaievglqilldG.keldlldl
VSYIRSQRAMAIT
| .| |. ..
vralrnsrlnsvq
|
|||||||||
| subfamily_PTPN3_pd | Subfamily PTPN3 | 821-1046 | 1.2e-25 | 85.0 | In-house | 55-274 (280) | alignment | ||
Range on Protein: 821-1046
Range on HMM: 55-274/280.0
DTRVVLKDYGTlfndDYIHANRVTCSHGLQLILSQApqEANGESCESTIESYWWTAKQEKSTQLVMMCDFDEKcpGKTNsCARYYPEsVGESMKFKNLTV
.||| ||. | ||| || | . . . | ..| . .| ...||. .||. . |. |.. | .|.|| ...... ...|
atrvklkeset....dyinanyvnmeipstglvnry..iatqGPlaktatdfWqmvweqksslivmlttlver..Grvk.ChqyWPe.tedeleygefsv
ECKSKIAEKDFETRELEVKFDG-HEPHTVTHSRLVGWNPLNVQPDTLLFTSLIQKIKNS----TTPVMVHCIDGISRSAAFASMIIGYQlVIQSLGSVKL
.|... ..| . .||| .| .| ..... . . | .| |. | ........ ..||.||| || |. . . . . .|.. .|
kcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklrsgkeePvvvhCsaGigrtGvlilletala.lieaaepvyp
EAVVSYIRSQRAMAITSALELAFVDAGIVKL
..|. .| |||| . .| || |.|.
ldivrtmrdqramlvqtasqykfvCeailkv
|
|||||||||
| subfamily_PTPN23_pd | Subfamily PTPN23 | 822-1039 | 7.9e-23 | 75.7 | In-house | 58-272 (288) | alignment | ||
Range on Protein: 822-1039
Range on HMM: 58-272/288.0
TRVVLKdygtLFNDDYIHANRVT--CSHGLQLILSQAPQEangesceSTIESYWWTAKQEKSTQLVMMCDFDEKcpgKTNSCARYYPESVGESMKFKNLT
.||.|. .|||| | | . ..| .|||.. ||. .| ..|| .||. . .|. . ....||.||. ||..||..|.
nRvklr....gskDDYinAsfvkdlspgcPdfiatqaPlq.......stlnDFWlmvyeqkssviVmllskeel...gkpkvdrYwPedkgetvkfgdls
VECKSKIAEKDFETRELEVKFDGHE-PHTVTHSRLVGWNPLNV--QPDTLLftSLIQKIKN--------STTPVMVHCIDGISRSAAFASMIIGYQLVIQ
| .||. . . |.|.... ... ..|.| .| | | | |.||| ....... | ||..||| |. |. .|| .. . . .
vtlksvretethvervlkletldadavksvshlqltsWpelGvPasPetll..qfldevesayeavqrksktPlvvhCsaGvgRtgvfalvyaavrelek
SLGSVKLEAVVSYIRSQRAMAITSALELAFV
| . . ||| .| || . .| |.
gnglldiiqvvsrlreqRrfmvqekeqlkfs
|
|||||||||
| subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 824-1041 | 3.8e-22 | 73.3 | In-house | 71-283 (305) | alignment | ||
Range on Protein: 824-1041
Range on HMM: 71-283/305.0
VVLKDYGTlfNDDYIHANRVTCSH--GLQLILSQAPqeangesCESTIESYWWTAKQEKSTQLVMMCDFDEKcpGKTnSCARYYPESVGESMKFKNL-TV
.|. | . |||||| | | ..| .| | . ||. .|| |.| |.||.| | || ||.|.| . || ...|. |
avkldkps..psdyihanyvgcpmipekrficaqgp.......ldqtidefwwmviqnkveqivmlcktvel..gkl.kcaqywpaaqgeklelksgivv
EC--KSKIAEKDFET--RELEVKFDGHEPHTVTHSRLVGWNPLNVQPDTLLFTSLIQKIKNSTTPVMVHCIDGISRSAAFASMIIGYQLVIQSLGSVKLE
| || |.| | |.. . | . .| | . | | | | |. |. | |..||| || |. . .. . . . .
envsgskpmerdaeiqitllnltysgdqkmsvrhlqwtewpdrgvppckltslellsairgskvpivvhcsagigrtgtivaieyilekiaenkpcppmp
AVVSYIRSQRAMAITSALELAFVDA
.| .| |||..| . .. |.
elvkalrdqrafsiqndvqylfihr
|
|||||||||
| subfamily_Ptp69D_pd | Subfamily Ptp69D | 807-1041 | 5.8e-22 | 73.2 | In-house | 47-280 (307) | alignment | ||
Range on Protein: 807-1041
Range on HMM: 47-280/307.0
SEQMKQRLPIPL-VMDTRVVLKDYGTLFNDDYIHANRVTCS-HGLQLILSQAPqeangesCESTIESYWWTAKQEKSTQLVMMCDFDEKcpgKTNSCARY
..| | . .|||.|| . ||| |. . . . | .|.| |.||. .| . ..| .||. . .|| . . ||.|
enalknRyedikafDktRvkLkkingkedsdYinasfikgykekkkfiaaqdP.......veatigDfWRmiaeqevtlivmlsnltek...nrkkcakY
YPESvgESMKFKNLTVECKSKIAEKDFETRELEVKFDG------HEPHTVTHSRLVGWNPLNVQPDTLLFTSLIQKI----KNSTTPVMVHCIDGISRSA
.|. . ... .. |.. |. .|. |||.| . .. . |. . ||. .| . ||... |.. .|..||| | .||.
Wpie..devqygdilvklvseekhsdyiiReldvskkkeesgevedsrkvvqyhytgWkDskvPevargllklieqvrelyklnrsPivvhCsaGvgrsg
AFASMIIGYQLvIQSLGSVKLEAVVSYIRSQRAMAITSALELAFVDA
| .. . | .. .|.. ..| .|||| . ..| |.
ifvaldsllqq.lkaedkvdifetvkdLrsqRnllvqsleqYvflyr
|
|||||||||
| subfamily_PTPN6_pd | Subfamily PTPN6 | 810-1039 | 3.4e-21 | 70.5 | In-house | 56-289 (306) | alignment | ||
Range on Protein: 810-1039
Range on HMM: 56-289/306.0
MKQRLPIPLV-MDTRVVLKdYGTLFNDDYIHANRVTCSHGLQLilsqAPQEANGESCESTIESYWWTAKQEKSTQLVMMCDFDEKcpGkTNSCARYYPES
|.| | .|||.|| . ..||| || .. . . . | . |.|.. .| . ||.|. .||. |. | . ||||.|..
eknryknilPfDhtrvilk.epsvpgsdyinanyikkevkgsd....ksyiatqgclettvsdFWrmvwqensrvivmttkevEr..g.kekCarYWPde
VGESMkFKNLTVECKSKIAEKDFETRELEVK--FDGHEPHTVTHSRLVGWNPLNVQPDTLLFTSLIQKIKNST--------TPVMVHCIDGISRSAAFAS
... . ...|.. |. . .|.. ||| |. ...| ..| . . | .|. |. . ........ . |..||| .|| | .|
eekee.yGkisvtnvseksladYilRelsvskkkkkkeerevfqyhfksWPdhgvpkdpgavLdfledvnrkqeeleeaeagpivvhCsaGiGRtGtfiv
M--IIGYQLVIQSLGSVKLEAVVSYIRSQRAMAITSALELAFV
. .. . .. .| ..|.|| . . ||
iDillkliekkgldadidiqklvksvreqrsglvqteqqykfv
|
|||||||||
| subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 803-1039 | 6.8e-21 | 69.4 | In-house | 41-275 (290) | alignment | ||
Range on Protein: 803-1039
Range on HMM: 41-275/290.0
EALKSEQMKQRLPIPLVM-DTRVVLKDYGTL--FNDDYIHANRVT-CSHGLQLILSQAPqeangesCESTIESYWWTAKQEKSTQLVMMCDFDEKcpGKt
. .|.. ..| .| | |..|.. . ...||.| . .. | |. |.| ..|. .| .|||.| .||... |. ||
gltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgykekkqyiatqgp.......vsntlvdFWkliwqekvtiivmltniiee..gk.
NSCARYYPESvgESMKFKNLTVECKSKIAEKDFETRELEVKFDGH--EPHTVTHSRLVGWNPLN----VQPDTLLFTSLIQ-KIKNSTTPVMVHCIDGIS
. | |.|.| .. .. . ... . . ... .|.|||| . ....||. .. |.. | .|... .. . |. |...||| |...
vkCqqYWpds..dtkaygefsikllneetlneyierklevknknsagakqsvtqyqitnwdstgkvtnpqtillvieemyktqrkrgntsivvHCSdtvg
RSAAFASMIIGYQLViQSLGSVKLEAVVSYIRSQRAMAITSALELAFV
||| | .. .. . . .. | . . .|. |.|. .... .. ..
rsavfcaaattinkc.ktegvidvfqvlksqRiqkpgsvqtvqqyqgi
|
|||||||||
| subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 821-1044 | 1.1e-20 | 68.9 | In-house | 55-273 (281) | alignment | ||
Range on Protein: 821-1044
Range on HMM: 55-273/281.0
DTRVVLKDYGTLFNDDYIHANRVTCSH-GLQLILSQAPqeangesCESTIESYWWTAKQEKSTQLVMMCDFDEKcpgKTNSCARYYPESVgESMKFKNLT
|||.... . | ||| || | . . | .|.| ......|. ..| ...||. |. | ||.|. ...|. ..|
atrvkvtpneenkntDYinanfvpgykgekeyiatqgP.......vPaslvafWqmvweqkvsaivmvtreiea...gklkChrYWPddn.selkygdvt
VECKSKIAEKDFETRELEVKFDGHEPHTVTHSRLVGWNPLNVQPDT---LLFTSLIQKIKNSTT--PVMVHCIDGISRSAAFASMIIGYQLVIQSLGSVK
|. ... ... . .|..... .. |. .|.. . . | | .| | | . ..|.... | |...|| |. |. .. .. . | ..| ...
vkstaeeekatyierkfkleresgetreveqlaytaWPdhGvPattkellefrkevlkltekktkaplvihCsaGvGrtGtyialDrlvkaveaeleeld
LEAVVSYIRSQRAMAITSALELAFVDAGIV
..||| .| .| . . . . .|| ..
vkavvaelrkernlmvqtvvqyefvykavl
|
|||||||||
| subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 808-1043 | 1.3e-20 | 68.7 | In-house | 47-275 (288) | alignment | ||
Range on Protein: 808-1043
Range on HMM: 47-275/288.0
EQMKQRLPIPLVMD-TRVVLKDYGTLFNDDYIHANRVTCSHGL-QLILSQAPQEangesceSTIESYWWTAKQEKSTQLVMMCDFDEKcpgKTNSCARYY
. | | . | .| .|| ||. . . ||| |. . ... . | .|.| .|.. .| ..|.. .||. .. |. . | .|.
nakknRyrnilpyDekrvklkkleeeagaDYinasyidgekkkkkyiatqgPla.......dtvndfWelvyenktstivmltelveg...gktkCeeYW
PESvGESMKFKNLTVECKSKIAEKDFETRELEVKfDGHEPHTVTHSRLVGWNPLNVQPDTLLFTSLIQKIKNS----TTPVMVHCIDGISRSAAFASMII
|.. .. .. ..||. ... ..|| .|.|... .. ..|. . .| .| .. . |....|.. | |..||| .|. |. | ..
Pda.dkpknyGsvtvtlveskeledfvlrkllle.kkkteleitqyqylaWpdhgvPeskapllellrqvkvanqadtgpiivhCsaGvGrtgtFialda
GYQLvIQSLGSVKLEAVVSYIRSQRAMAITSALELAFVDAGI
. ... . . ..|. .| |||. . |. .
lida.veeedyiDvagtvaklRkqRallvqtlkqYefiyevl
|
|||||||||
| subfamily_PTPN13_pd | Subfamily PTPN13 | 820-1048 | 1.3e-20 | 68.9 | In-house | 50-270 (273) | alignment | ||
Range on Protein: 820-1048
Range on HMM: 50-270/273.0
MDTRVVLKDYGTLFNDDYIHANRvtCSHGLQLILSQAPQeangescESTIESYWWTAKQEKSTQLVMMCDfdEKCPGKTnSCARYYPESVGESMKFKN-L
.||| |.| |. | ..|... . . |..| | |.. .| . |.. ..|. || || | ||.||| ....| .| |
detrvklgdeggyinaslikvpv..gkdeyeyiacqGPl.......Petvkdfwqmvweqkaeviamvtl..ekekgkv.kchrywPesknkklkvsnrl
TVECKSKIAEKDFETRELEVK-FDGHEPHTVTHSRLVGWNPLNV--QPDT-LLFTSLIQKIKNSTTPVMVHCIDGISRSAAFASMIIGYQLVIQSLgSVK
.|| ..| |.|.|| . | . |.| ..| | .| ... | | . .........|..||| || || .. .. . .|. . ...
evellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaellqfvaevrrlqtdagPivvhcsaGiGrsGtlitidvvlglierdk.efd
LEAVVSYIRSQRAMAITSALELAFVDAGIVKLLG
.. .| .| || . . || |...|.
vkeivrklreqrqgvvqtkdqyifvykailevlk
|
|||||||||
| subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 821-1043 | 1.8e-20 | 67.5 | In-house | 57-272 (515) | alignment | ||
Range on Protein: 821-1043
Range on HMM: 57-272/515.0
DTRVVLKDYGTLFNDDYIHANRVTCSHG-LQLILSQAPQEAngescesTIESYWWTAKQEKSTQLVMMCDFDEkcpGKTNSCARYYPESVGESMKFKNLT
.|| |. . ||. | . . | ||.|..| ... .| ||. | ..|. . | | |..|.|. |.|.|| ..
svrvklevindnPhsdyfnasyipsfdndkayiasqgPnka.......svddfWrlvlqenvttiamvtklke...gdkikcgkyWPdkpgdsvkfGsik
VECKSKIAEKDFETRELEVkFDGHEPHTVTHSRLVGWNPLNVQPDTLLFTSLIQKIKNST----TPVMVHCIDGISRSAAFASMIiGYQLVIQSLGSVKL
|| | | . |.|.| | . .||| .. .| |...| . ||...| .. |...|| |. | . |. .. .| .
velvsleactggikrkltv.lkgddsrtvtqfhfteWPdkGvpkhtssllklikevkadhgqythpliihcsaGvGrtGvvisid.svvahakttrmvdv
EAVVSYIRSQRAMAITSALELAFVDAGI
.| || .| . . ||. .
fnfvtnirqkrpylvqtqeqyafiygav
|
|||||||||
| subfamily_PTPRD_pd | Subfamily PTPRD | 790-1052 | 2.1e-20 | 67.9 | In-house | 29-286 (564) | alignment | ||
Range on Protein: 790-1052
Range on HMM: 29-286/564.0
FDAMNEKYEVPGREALKSE-QMKQRLPIPLV-MDTRVVLKDYGTLFNDDYIHANRVTC-SHGLQLILSQAPqeangesCESTIESYWWTAKQEKSTQLVM
. ..|. ... ..| |.. ..| |. . .||||. . . ||| |. . . . | .|.| ..||| .| ...|. ||
ykkieegqqftweaankpaNkaKNRyanivaYdhsRVvLskvegdegsDYINAsfidgyrkrkayIAtqgP.......laetiedFWRmvweqnsstiVm
MCDFDEKcpgKTNSCARYYPESvGeSMKFKNLTVECKSKIAEKDFETRELEVK-FDGHEPHTVTHSRLVGWNPLNVQPDTLLFTSLIQKIKNS----TTP
. || ... |..|.||. | . .. .|||. ... .|.| |....| . .| ..|.. . | .| . . .||.|.... . |
ltkleEk...gkvkchkYWPek.g.tetygeltVtleeeeeladyeirtfklkkkkssesreVrqFhFtsWPdhgvpesatslLdlirkvralnepdagP
VMVHCIDGISRSAAFASMIIGYQLvIQSLGSVKLEAVVSYIRSQRAMAITSALELAFVDAGIVKLLGLFVD
..||| |. |. .| . . . |.. . | . .|. .|.|| . . . .|. |.. | ...
ivVhCSaGVGRTGtfividamler.ikeektvDiyqyvkalrkqRnamVqteeQYiFiheailealacgnt
|
|||||||||
| subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 814-1044 | 2.2e-20 | 67.8 | In-house | 30-261 (270) | alignment | ||
Range on Protein: 814-1044
Range on HMM: 30-261/270.0
LPIPlvmDTRVVLKDYGTLFNDDYIHANRVTCSHG--LQLILSQAPQEAngescesTIESYWWTAKQEKSTQLVMMCDFDEKcpgKTNSCARYYPESVGE
|| | |||.|.. . . || || | .| . | ...|... |..|.| . .||.| .||. .. || .. |.||.|....|
LPsP...atRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpt.......tlksfwrmiweekvtaivmttgleEk...grkkCerYWpaepke
--SMKFKNLTVECKSKIAEKDFETRELEVKFDGHEpHTVTHSRLVGWNPLNV--QPD-TLLFT---SLIQKI---K---NSTTPVMVHCIDGISRSAAFA
.... ...| |. |. . ...|... .|.| . ..| . |. | ..| .| . ...... . . ..|..||| .|. |. .
kvkledgkikvlalseekeegyiltrlrleekgee.rrlvHfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcsaGvgRtGtli
SMIIGYQLvIQSLGSVKLEAVVSYIRSQRAMAITSALELAFVDAGIV
. |. .| ... ..| . |... .| .| . . .|. ...|
alDiavrl.LeetkkvdvlaiieelRkdRmalvqhpeqyeflykavv
|
|||||||||
| subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 814-1030 | 2.6e-20 | 67.2 | In-house | 44-251 (281) | alignment | ||
Range on Protein: 814-1030
Range on HMM: 44-251/281.0
LPIPLVMDTRVVLKD-YGTLFNDDYIHANRVTCSHG-LQLILSQAPQEangesceSTIESYWWTAKQEKSTQLVMMCDFDEKcpgKTNSCARYYPESVGE
| || . .|| || |||||| . ||.| |.. | .| ||..| .||.|.| | . . || |.|
lnipcldisrvqlkvkmpnknstdyihanyirspflkrgyiltqgpkk.......etradfwrmiwqenttaivmlcqflet...nrekcaeyfprnahc
SMKFKNLTVECKSKIAEKDFETRELEVKFDGhEPHTVTHSRLVGWNPLNVQPDTLLFTSLIQKIKNSTTPVMVHCIDGISRSAAFASMIIGYQLVIQSLG
..| .|.|. . .| . | |.. ..| | . .|| | .| . .. ...||. .|| ..|| |. || .. .. | | . .
clqfdklsvsyedstvnkslvttrlnlsyeg.etrlithwlwkewpdwqvpessevmlkilrkirarstppvihcsagvgrsgtlmaveialqsihshft
SVKLEAVVSYIRSQRAMAI
.. .||..| |
lpdikqivshlrvtgraas
|
|||||||||
| subfamily_egg_pd | Subfamily egg | 818-1044 | 4.2e-20 | 66.6 | In-house | 51-267 (307) | alignment | ||
Range on Protein: 818-1044
Range on HMM: 51-267/307.0
LVMDTRVVLKDYGTLFNDDYIHANRVTCSHGL-QLILSQAPQEangesceSTIESYWWTAKQEKSTQLVMMCDFDEKcpgktNSCARYYPESVGESMKF-
.|| |. . ||.|||||| | ..||.||| | . .| ||. .||. | . | |.| . .|...
ckdssrvklelrrGqylddfihanrvkGkpllnefilaqaplk.......ntvddfwrmvfqeevqyivmltsrkes.....erceyywpkaesdslvtv
-KNLTVECKSKIAEKD--FETRELEVKFDGHEPHTVTHSRlvgWNpLNVQPDTLLFTSLIQKIKNSTTPVMVHCIDGISRSAAFASMIIGYQLVIQS-LG
.| .|. . | | .| . .| . | . .. .| | ...|..| ..||.|..|.|.|..|.. .. | ... .
pGslrienlkvdskadplfrvtklklvGgddeerflehwq...gd.vnnssdvysplrvlrklrnlskpvvvqdilGvskaatlvaieiallsllrGpit
SVKLEAVVSYIRSQRAMAITSALELAFVDAGIV
. | ..| .| ... |.| || ..
kslvlravvflrlrrrlsvesvllylfvyrlvl
|
|||||||||
| subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 802-1038 | 4.7e-20 | 66.8 | In-house | 35-268 (307) | alignment | ||
Range on Protein: 802-1038
Range on HMM: 35-268/307.0
REALKSEQMKQRL-PIPLVMDTRVVLKDYGTlfNDDYIHANRVTCS-HGLQLILSQAPQeangescESTIESYWWTAKQEKSTQLVMMCDFDEKCpgKTn
||..... |.| .. . .|.|.| | |||||| . . . ..| .| |. |.|. |.| | ||| ..|.|. | . |
veafsantdknryqdvkcqdkgrivvkfdgl..asdyihanylgiaikpkkficaqgpl.......entqysfwamaiqekvesvimlckviela..ki.
SCARYYPESVGESMKFKN----LTVEC--KSKIA--EKDFETRELEVKFdGHEPHTVTHSRLVGWNPLNVQPDTLLFTSLIQKIKNSTTPVMVHCIDGIS
| .|.| |. . | . ..|. |.| |. . .|.|.. ... |..| . | | . | |.. .. | ||.||| |.
kceqywpleegqklvfgeapntisvanlgakklapdedlinvttlkvdw.aqksrtiqhlqwenwpdrgvpqinltainlleavrydtnpvvvhcsaGvG
RSAAFASMIIGYQLVIQSLGSVKLEAVVSYIRSQRAMAITSALELAF
|| . .. . . .|. ... .| .|||| || . .. .
rsGtivaislvqdkmiaGinckdmkklveelrsqrhyaiqteaqyly
|
|||||||||
| subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 812-1044 | 4.9e-20 | 66.6 | In-house | 48-274 (315) | alignment | ||
Range on Protein: 812-1044
Range on HMM: 48-274/315.0
QRLPIPLV-MDTRVVLKDYGTLFNDDYIHANRVTCSHG-LQLILSQAPQEAngescesTIESYWWTAKQEKSTQLVMMCDFDEkcpGKTNSCARYYPESV
| | .||.|. ..||| | . . | ||.|..| ... .| ||| | .||. . .| | .|..|.|.
nryknilPldsarvkleviddsPdsdyinasyiksvdddkayiasqgPlka.......svddfwrmvlqekvttivmvtkkqe...gdkikcrqywPdrk
GESMKFKNLTVECKSKIAEKDFETRELeVKFDGHEPHTVTHSRLVGWNPLNVQPDTLLFTSLIQKIKNS----TTPVMVHCIDGISRSAAFASMIIGYQl
..|..| .. || | | | .|.| | ...| .||| .. .| |. .| . ||...| . . ...||| |. |. . |. .
adsvefGsikvellsleadtdgvarkl.vtrkseesrtvtqfqftewPdkGvdkqtssllklikevkadngkkefsllvhcsaGvGrtGvvisidevva.
VIQSLGSVKLEAVVSYIRSQRAMAITSALELAFVDAGIV
|. || . .| .|..| . . | ||. .
qikrtrsvdvfnfvknlrakrpylvqteeeyafiydavl
|
|||||||||
| subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 809-1045 | 5.1e-20 | 66.8 | In-house | 49-286 (325) | alignment | ||
Range on Protein: 809-1045
Range on HMM: 49-286/325.0
QMKQRLPIPLVMD-TRVVLKDYGTLFNDDYIHANRVTCSHGLQLIL-SQAPQEAngescesTIESYWWTAKQEKSTQLVMMCDFDEkcpgKTNSCARYYP
. | |.. . .| .||||. . . ||| |. . . . | .|||. | ||. | . . ... .|.. .|. . ..|| |.|
kaknrfknvvaldksrvvletkkddpssdyinasylrddkkkdvflaaqaPlta.......tindlWrlvldWrcsvvvvlneldl....gkdrcavywp
ESVGESMKFKNLTVECKSKIAEKDFETRELEVKF-DGHEPHTVTHSRLVGWNPLNV--QPDTLL-FTSLIQKI----KN---STTPVMVHCIDGISRSAA
. .|.| .| | |. .. |. | |.|| .. | .| .| .|. . | .| ||. .. |.... . ..||..|||..|. |. .
kemgksktfGglevklrtieeisdyvhrvldvkqvkkGetrsvkqfqlqswddmGvqkrpatlisilqlvkavservtantkastpilvhcsaGvGrtGv
FASMIIGYQLVIQSlGSVKLEAVVSYIRSQRAMAITSALELAFVDAGIVK
|.|. . ||. .| . .| .| .| . .. . .. ..|.
fislysalakviee.srvdifgfvkklrkdrpsmvetvdqyiliyealve
|
|||||||||
| subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 838-1044 | 2.6e-19 | 64.1 | In-house | 78-278 (301) | alignment | ||
Range on Protein: 838-1044
Range on HMM: 78-278/301.0
IHANRV-TCSHGLQLILSQAPQEAngescesTIESYWWTAKQEKSTQLVMMCDFDEKcpgKTNSCARYYPESVGESMKFKN--LTVECKSKIAEKDFETR
|||| . | | ..| .|.| .. | | .| .| . ..||.. . || ... |. |.| ...|... . .... | .| .|. |
ihanwiptsGhphrfiatqgPlkn.......tsedfwamlvqydvekivmlgqkvek...leekceeylpvkisekldigrfkikiknkelilnkkiskr
ELEVKFD--GHEPHTVTHSRLVGWNPLNVQPDTLLFTSLIQKIKNSTTPVMVHCIDGISRSAAFASMIIGYQLViQSLGSVKLEAVVSYIRSQRAMAITS
.|||. ...|||| . . | .| |.. .|.| |..||| .|| || || . . . | .. ..| . .| .| ..
tlevedstgkfatrtvthyqysewtdrgvPkshaelfdlmelvkksekPivvhcsaGiGrsvafigteylarev.eadptieltealkhlrehrwngvqt
ALELAFVDAGIV
| .. | |
nsqlywmtlGtv
|
|||||||||
| subfamily_PTPRB_pd | Subfamily PTPRB | 819-1047 | 3.5e-19 | 64.0 | In-house | 63-285 (293) | alignment | ||
Range on Protein: 819-1047
Range on HMM: 63-285/293.0
VMDTRVVLKDYGTLFNDDYIHANRVTCSHGLQ-LILSQAPqeangesCESTIESYWWTAKQEKSTQLVMMCDFDEKcpGKTNsCARYYPESVgESMKFKN
.|| |.. . ..||| || . . . | .| | .|.. .| ..||. .||. . || ||. | .|.|. |.. . .
ydhsrvkLaalkdesgsDYinanyipgynsprefiatqGP.......lpetvddfWrmvwekkssiivmltqlvek..gkvk.CeeYWPade.epvlyGd
LTVECKSKIAEKDFETRELEVKFdGHEPHTVTHSRLVGWNPLNVQPDTLLFTSLIQKIK------NSTTPVMVHCIDGISRSAAFASMIIGYQlVIQSLG
..|. ... .|. .|||... ..| ..|.. . . | .| .| . ....... .|..|..||| |. |. .| .. | |..
ikvtlvaeeeledwvirelkiek.ekeerkvrqyhftsWpdhgvPektktlldfvrtvreaiektaskrPivvhCsaGvGRtGtfialdrllq.aieeed
SVKLEAVVSYIRSQRAMAITSALELAFVDAGIVKLL
| . ..|. .|..|.. . . . |.. ...||
yvdifgivaelReeRnllvqtekqYifihqcvldll
|
|||||||||
| subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 808-1052 | 7e-19 | 63.2 | In-house | 56-295 (298) | alignment | ||
Range on Protein: 808-1052
Range on HMM: 56-295/298.0
EQMKQRLPIPLVMD-TRVVLKDYGTLFNDDYIHANRVTCSHGL-QLILSQAPqeangesCESTIESYWWTAKQEKSTQLVMMCDFDEKcpgKTNSCARYY
. | | . . .| .||||.. . . ||| | . .| |..||| ..|.| .| .|... .||. . |. .. . .|.
nkkkNRyadiialdssRvvLekedadeesdYiNAsflhaykgrnafiatqaP.......ltetvedFWrmvteedigtiVmltnleel...dktkyhkyw
PESvgESMKFKNLTVECKSKIAEKDFETRELEV-KFDGHEPHTVTHSRLVGWNPLNVQPDTLL---FTSLIQKIKNSTT--PVMVHCIDGISRSAAFASM
|.. .. .. ..||. .|| |...|.|.| | . .. ..| . . . | | . . . ... .. . ||.|.| .|. || .| .
Pde..gketygeitvsllskeefadlivrklkvskkkeekerevrqlhftsWpdkgvpenatsvldllrkvrasqqqagnkpvivqCsaGvgRsGtfiai
iIGYQLVIQSLGSVKLEAVVSYIRSQRAMAITSALELAFVDAGIVKLLGLFVD
.. .| . || ..| .|. |... . .|. . . | | |
.dsvlervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavlealdsfnd
|
|||||||||
| subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 834-1032 | 7.6e-19 | 62.7 | In-house | 61-251 (283) | alignment | ||
Range on Protein: 834-1032
Range on HMM: 61-251/283.0
NDDYIHANRvTCSHGLQLILSQAPqeangesCESTIESYWWTAKQEKSTQLVMMCDFDEkcpGKTNSCARYYPESvGeSMKFKNLTVECKSKIAEKDFET
| .| .. .. . | .|.| . |. .| .|| | .||. . | .. |..|.|. | |... ..|| . ... |
navfipvsk.sykqdkkyiiaqsP.......ldrtvvdfWkmvfdekitaivmltklqe...dlrikCsqyWPkr.G.sedyGeftvtlrkettsnsfii
RELEVKFDG--HEPHTVTHSRLVGWNPLNVQP--DTL-LFTSLIQ-KIKNSTTPVMVHCIDGISRSAAFASMIIGYQLViQSLGSVKLEAVVSYIRSQRA
.|| .. .. .. ..| ....| . |. ..| | .| . .. .|..||| || |.|.| .. . . .. | . ||| .| ||
kelllrvnssakstlllahyqvidWleygeqaiinslvkfnkvislqteskkgPivvhCstgiGrtavfiaasasvkda.ltesvvdvfavvkimreqrm
MAITS
||. .
mavqt
|
|||||||||
| subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 804-1048 | 1e-18 | 62.5 | In-house | 43-284 (319) | alignment | ||
Range on Protein: 804-1048
Range on HMM: 43-284/319.0
ALKS-EQMKQRLP-IPLVMDTRVVLKDYGTLFNDDYIHANRVTC-SHGLQLILSQAPQEangesceSTIESYWWTAKQEKSTQLVMMCDFDEKCpgKtNS
| | . | | . | . |||||... . ||| |. . . . | ||| | ||| .| .|.| .||... || |
askeenkkknryqnilaydrtrvvlseldgvegsdyinasfidgyqerekfiatqaPle.......ntiedfWrmvWeeessivvmltklvekl..k.vk
CARYYPESvgESMKFKNLTVECKSKIAEKDFETRELEVKFDGHEP--HTVTHSRLVGWNPLNVQPDTLLFTSLIQKIKNST-----TPVMVHCIDGISRS
. .|.|| . ... .|.|. ... .|.. |.|... | .|.| | .| .... |...|..|. |..||| .|. |
lkkywpee..nfeeyGrlivtleeeeeledyiirklklnkkssevetRevkhfqyteWpdhdvPekatslldllkrirksrektqsgPivvhCsaGvGRt
AAFASMIIGYQLViQSLGSVKLEAVVSYIRSQRAMAITSALELAFVDAGIVKLLG
.| . . . | . | . . .|| .| || . . |. ... .
Gtfivldamlerv.keegvlDvfstvsrlRtqRnimvqrpeqYkfiyealleave
|
|||||||||
| subfamily_PTPN12_pd | Subfamily PTPN12 | 821-1047 | 1.7e-18 | 61.5 | In-house | 54-277 (290) | alignment | ||
Range on Protein: 821-1047
Range on HMM: 54-277/290.0
DTRVVLKDYGTLFNDDYIHANRVTCSHG-LQLILSQAPqeangesCESTIESYWWTAKQEKSTQLVMMCDFDEKcpgKTNSCARYYPESVGESMKFKNLT
.||.|. ..||| || . ..| |. | .|.| |.. .| . . . .||.| | . . |.||.||...|...| ...
ksrvelskieeeegsdYinanfikgvegkleyiaaqgP.......LpktlddfWrmiweknveivvmaCrevel...gkkkCerYWpeegeeelefgefe
VECKS-KIAEKDFETRELEVKFDgHEPHTVTHSRLVGWNPLNVQPDTLLFTSLIQKIK----NSTTPVMVHCIDGISRSAAFASMIIGYQLVIQSLG--S
|.... | ..|| | |.|... .| ..|. . | .| . .||.... .. .|..||| |. | . .. . ..|. . .
vtleeekavdddflirtLkveaq.kesrkvyqfhYtaWPDhgvPssaksllelielvrelqesedaPlvvhCsaGvGrtGtiiaidyvrellkaekipee
VKLEAVVSYIRSQRAMAITSALELAFVDAGIVKLL
... .| .| ||| .. . .| ...|.
ldvfdlvlelrkqraalvqtkeqyelvykavaelv
|
|||||||||
| 0044763 | (Phosphotyrosine protein) phosphatases II | 820-1031 | 3.2e-18 | 61.4 | In-house | 3-155 (178) | alignment | ||
Range on Protein: 820-1031
Range on HMM: 3-155/178.0
MDTRVVLKDYGTLFNDDYIHANRVTCShglqLILSQAPQeangescestiESYWWTAKQEKSTQLVMMCDFDEKCpgkTNSCARYYPESVGesmkfknlt
.|||.| . |. |||.|.... |.|...|. .... |... | .|.... .| ..| .|.||. |
drtrvllsnleglersdyinaseilpg....lylgslpp...........addlellkelgithivnlteelelg...flkcdpywpeeag.........
veckskiaekdfetrelevkfdghepHTVTHSRLVGWNPLNVQPDTLLFTSLIQKIK-NSTTPVMVHCIDGISRSAAFASMIIGYQLviqslgSVKLEAV
.. | ...... .. .| |. .|... .. || ||| |..||.... . . ..| .. ||..
..........................iqylhipipDhgvpdllehflefvefieealdekggpvlVHCsaGvgRsgtlvaaylmkkl......glsleea
VSYIRSQRAmAIT
....|..| ...
ielvrerRp.ivp
|
|||||||||
| 0041856 | (Phosphotyrosine protein) phosphatases II | 831-1032 | 4.5e-18 | 60.9 | In-house | 17-156 (182) | alignment | ||
Range on Protein: 831-1032
Range on HMM: 17-156/182.0
TlfNDDYIHANRVTCSHGL-QLILSQAPQEAngescesTIESYWWTAKQEKSTQLVMMCdfdekcpgktnsCARYYPesvgesmkfknltveckskiaek
. |||.|| . .|. . |. |.| |..... . |... | .|... . .|.|
r..dldyInanlylgslpatrfiatqgplls.......tvadflrmlkelgittivnlt............eelywp.......................
dfetrelevkfdGHEPHTVTHSRLVGWNPLNVQPdTLLFTSLIQKIKNSTTPVMVHCIDGISRSAAFASMIIGYQLviqslgSVKLEAVVSYIRSQRAMA
........ . ..| .| . . . ..|...... || ||| |..|..... . . ..| .| || .|...||.| ..
............ellerlgiqylylpwpDhgvpd.ldelldfieevleeggpvlVHCsaGvgRtgtlvaaylmkkl......gvsleeavklvrsrRpgm
ITS
...
vit
|
|||||||||
| subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 810-1043 | 9.9e-18 | 59.1 | In-house | 49-274 (287) | alignment | ||
Range on Protein: 810-1043
Range on HMM: 49-274/287.0
MKQRLPIPLVM-DTRVVLKdygtLFNDDYIHANRVTC-SHGLQLILSQAPqeangesCESTIESYWWTAKQEKSTQLVMMCDFDEKcpgKTNSCARYYPE
| || || . ||.|| ..||| | . .. . |....| .|. .| .... | .||.|. |. ... | .|.||
dknRltqilvpdnyrvllk....gehpdyinavfidgykekkafiiaesP.......mfntarnfWkliddrnvtaivmlcqeken...deevcyqyWpe
SvgESMKFKNLTVECKSKIAEKDFETRELEVKFDG--HEPHTVTHSRLVGWNPLN--VQPDTLL--FTSLIQ-KIKNSTTPVMVHCIDGISRSAAFASMI
. .|. . . ..| .. .... |.|||| .. ....|. .. |. .| | | . .. . |.. |...||| |.. ||| | ..
e..ksvvlGeyniellneevnagyierklevknknkagdkqqvkqyqitnWdstgkvtepqtillvieemyktqrkrgntsivvhCsdtvGrsamfcaaa
IGYQLViQSLGSVKLEAVVSYIRSQRAMAITSALELAFVDAGI
.. . . . | . . |. | |. .. . . |. .
ttinkc.kteGviDvfqvlksqriqkpgsvqtveqykfindiv
|
|||||||||
| subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 818-1044 | 1.1e-17 | 59.2 | In-house | 61-281 (297) | alignment | ||
Range on Protein: 818-1044
Range on HMM: 61-281/297.0
LVMD-TRVVLKDYGTLFNDDYIHANRVTCSHGlQLILSQAPQEAngescesTIESYWWTAKQEKSTQLVMMCDFDEKcpgkTNSCARYYPESVGESmkFK
| .| || |. .. . ||. | | . .|| .| |..| |.. .| .|. . .||. | .|. ...||||.... . |
LPydssRvkLaivnddpdsDyvnasfvkgnkh.rlittqmPmka.......tvadfWamvldeqvstivmlnddner....dkkcaryWsdkgvtt..fG
NLTVECKSKIAEKDFETRELEVKFDG-HEPHTVTHSRLVGWNPLNVQP--DTLLFTSLIQKIKN-----STTPVMVHCIDGISRSAAFASMIIGYqLVIQ
...|. .| . | |||||. . . | . | | .|. .. . ||. ... . .|..|||. |. | . . .. ..
dvsvvllsvsereGfikrelevtkgkakarrvvkqyqfveWPdkaverkdsassllklisevrkdfsqnaegPllvhclaGvGrtgvlltidsvv.aeak
SLGSVKLEAVVSYIRSQRAMAITSALELAFVDAGIV
.| . .|. .| .| . . .|| ..
rekevdifglvkklrqerpylvqtkeqykfvyvavl
|
|||||||||
| subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 779-1039 | 2e-17 | 58.1 | In-house | 5-260 (274) | alignment | ||
Range on Protein: 779-1039
Range on HMM: 5-260/274.0
EELIKKFYGVKFDAMNEKYEVPGREalKSEQMKQRLPIPlvmDTRVVLKDYGTLF-NDDYIHANRVTCSHGLQL--ILSQAPqeangesCESTIESYWWT
..| |.|. . . .|...|.| . . .. |. || . .||.|. . . .|| || . .. . . | | .|.. .|
kdlekeflelPlnfdqeeldvfgsq..tknryktilPne...nsrvllesessededssyinanyikGydeeskayvatqGP.......lpntvadfWrm
AKQEKSTQLVMMCDFDEKcpgKTNSCARYYPESVGE--SMKFKNLTVECKSKIAEKDFETRELEVKFDGHePHTVTHSRLVGWNPLNVQPDTLLFTSLIQ
||... .||. .. |. . . ||.|.|.. . | ..... .. .... ..|.. |.| .| . ...|.| | .. |. . .|..
iyqeevqvivmltklkea...neqkCavyfPdaedyeiserygdveikvekiverndysvrklvlkyler.ersvkhywytdWPdhksPddantlldlvl
KIK-------NSTTPVMVHCIDGISRSAAFASMIIGYQLViQSLGSVKLEAVVSYIRSQRAMAITSALELAFV
... . ..||.||| || | .| .. |. . . . . | . .|. .| .| . .. ..
eveesreeenaklapvvvhCsaGiGrtGcfiaisiavrql.reeivvdvlkivcnlrldrGGmvqtseqyeli
|
|||||||||
| subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 770-1043 | 2.9e-17 | 57.3 | In-house | 6-283 (305) | alignment | ||
Range on Protein: 770-1043
Range on HMM: 6-283/305.0
KETCIPFLSEELIKKFYGVK--FDAMNEKYEVPGREALKSEQ--MKQRLP-IPLVMDTRVVLkdyGTLFNDDYIHANRV-TCSHGLQLILSQAPQEange
| . |. . | | |.. | ||. .. .|.| | |.| . . . || | . . .||||| | | . ..| .||| |
kkqilkfvkrtlekgpaglraefvamkrfndfekmkafkeaqeagknrykdvgcldnnrvkl...egpwpheyihanyvstptnpkrfictqaple....
sceSTIESYWWTAKQEKSTQLVMMCDFDEKCpgkTNSCARYYPESVGESMKFKN----LTVECKSKIAEK-------DFETRELEVKFDGHEPHTVTHSR
| .|. |.| .. |.|.. || .. |. |.. .. ..|.. ..| ..| . | . . .| .. |.. . |||
...ktcadfwymclqdkveaifmlcnllekg...akkcleyfaskdkdvlefeekgqkisvkfessvtlkfrkdakakvtetvlviegpgekarkvthyh
LVGWNPLNVQPDTLLFTSLIQKIKNSTTPVMVHCIDGISRSAAFasMIIGYqLVIQSLGSVK---LEAVVSYIRSQRAMAITSALELAFVDAGI
. | | . | |..| . | |..||| || |. . ... | .. | |. . . .. || || .| . . || |
widwpdrgvpaadlailellekarpskgpivvhcsagigrtgsv..vmley.ildqllagqiiedtdkilqkireqrnnsiqtdaqylfvhqvi
|
|||||||||
| subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 820-1044 | 4.8e-17 | 56.7 | In-house | 51-274 (287) | alignment | ||
Range on Protein: 820-1044
Range on HMM: 51-274/287.0
MDTRVVLKDYGTLfNDDYIHANRVTC-SHGLQLILSQAPqeangesCESTIESYWWTAKQEKSTQLVMMCDFDEKcpgKTNSCARYYPESvGESMKFKNL
||||.| | | ||| || |. . . | .|.| .|. ..| ...|. ...| |. . | .|.|| |.
ddtrvllsaegel.GsdyinanyvasytddeafiaaqgP.......iaatvrdfwravletrsasvitmtrevee...arlkcykywPer.evPmrvGGy
TVEC-KSKIAEKDFETRELEV-KFDGHEPHTVTHSRLVGWnPLNVQPDT----LLFT-SL-----IQKIKNSTTPVMVHCIDGISRSAAFASMIIGYQLv
.| . .| | .. .| | . . ...| . | |. | | .| . | . |. . ... . . |..||. || || . .... .
svvlldydikePeygvralrlidletrearvvkqldllsw.PdkvlaPtavglirfvldvkqhielardasevGPlvvhddvGiGrsGillatlvlvsr.
IQSLGSVKLEAVVSYIRSQRAMAITSALELAFVDAGIV
..|| | ||| ..| .|| . ... | .. .|
ledlGrvdvaavvirlreyraalvqavvqlrllyealv
|
|||||||||
| 0051429 | (Phosphotyrosine protein) phosphatases II | 835-1041 | 5.7e-17 | 57.7 | In-house | 4-219 (272) | alignment | ||
Range on Protein: 835-1041
Range on HMM: 4-219/272.0
DDYIHANRVTCShgLQ------LILSQAPQEAngescesTIESYWWTaKQEKSTQLVMMCDFDEKcpgKTNSCARYYP----------ESVGESMKFKNL
..||.|. | . |..|..| .. |....|. |... . |.... .|. . . | || | ... ... . .|
sgyiNardvggy..grvvkpgrlyrsggplpl.......taadfwrl.kelgiktivdLrseeEr...grlkcdrywpgirylhlpilddsaptilygal
TVECKSKIAEKDFETRELEVKF--DGHEPHTVTHSRLVGWNPLNVQPDTllFTSLIQKIKNsTTPVMVHCIDGISRSAAFASMIIGYqLVIQSLGSVK--
.| . |.. |. |||.... . .|...|.| .| .| ... . .|.. . . ||.||| |..|.. .. ... . | . |.
rvtllseellldyilrellltlllsagearevmhlhytdwpdhgvpqea..llellellld.ggpvlvHCsaGkdRTGtvvalllll.lgvsletivddY
------LEAVVSYIRSQRAMAITSALELAFVDA
||..|...|.||. |. . ..|.
lltnlyleeaveelraqrpgavqteeqylflye
|
|||||||||
| subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 819-1040 | 7.9e-17 | 56.1 | In-house | 47-263 (285) | alignment | ||
Range on Protein: 819-1040
Range on HMM: 47-263/285.0
VMDTRVVLKDYgtlfNDDYIHANRVTCSHGLQ--LILSQAPqeangesCESTIESYWWTAKQEKSTQLVMMCDFDEkcpGKTNSCARYYPESVGESMKFK
. .||||||.. . |||||. . | | .| | |. .| ||| . ..|.| . | | . || |||| .|| .||
ieetrvvlknh....drdyihaswmrmpgkdqstyittqgp.......lpetlsdfwhmiyqekiayvlmlctlfe...ggvekcalyypeklgevvkfg
NLT---VECKSK-IAEKDFETRELEVKF-DGHEPHTVTHSRlVGWNPLNVQPDT----LLFTSLIQKIKNSTTPVMVHCIDGISRSAAFASMIIGyQLVI
. ||| . || ... . || . | . | | | .. |. . . ..|.. .|. ||| |. |.|.| . . |
kyeitlteckeeaiagtilnaltvintedasseplymnhvq.vpwwpdqlapedarpmielykwvkkvnpkekpicvhcsagvgrtatfvgidya.tiri
QSLGSVKLEAVVSYIRSQRAMAITSALELAFVD
... .| .|. | |. | ... |.
menpniemldivremramrfqavqshmqflfly
|
|||||||||
| subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 821-1048 | 8.5e-17 | 56.2 | In-house | 60-281 (318) | alignment | ||
Range on Protein: 821-1048
Range on HMM: 60-281/318.0
DTRVVLKDYGTLFNDDYIHANRVTCSHGL-QLILSQAPqeangesCESTIESYWWTAKQEKSTQLVMMCDFDEKCPGKtnsCARYYPESvgESMKFKNLT
.||| |.. . . ||| || . . . | .||| ||| .| . .|. .||. . |.. | ..||.|.. .|.....|.
htrvkLqmlegeegsDyinanyidGyrrkkayiaaqaP.......lpetieDfWrmvWeqnsavivmltqeeergkak...vhryWPsk..gsrsygklv
VECKSKIAEKDFETRELEVKFDGH-EPHTVTHSRLVGWNPLNVQPDTLLFTSLIQKIKNST-----TPVMVHCIDGISRSAAFASMIIGYQLvIQSLGSV
|| |... .|. ||..|. ... | .| . | .| .. . .|...... .|..||| |. | | . | . |. . |
velkeevelsdyvlrefkvtrteeeesrqvrqyhytsWpdegvpesgaslldlvrqvskaqqksgagpivvhCsaGvGrtGvfiavdiller.ikaealv
KLEAVVSYIRSQRAMAITSALELAFVDAGIVKLLG
. .|. .|.|| . . |. ... |
Dvfqtvkqlreqrnlmvqtedqyefiydvlleala
|
|||||||||
| subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 821-1051 | 8.7e-17 | 56.1 | In-house | 23-246 (250) | alignment | ||
Range on Protein: 821-1051
Range on HMM: 23-246/250.0
DTRVVLKDYGTLFNDDYIHANRVTCSHGLQ-LILSQAPqeangesCESTIESYWWTAKQEKSTQLVMMCDFDEKcpGKTnsCARYYPesVGESMKFKNLT
.||||. . . ||| | . .. . | .|.| ..||| .| .|||. .||. .. |. .|| . .|.| | .. |. ..|
ssrvvLekekgdkesdyinasflhgyderkafiatqgP.......lqatiedfWrmvleeksgtivmLtnLkes..ekt..yhqywP..vekaekyGdvt
VECKSKIAEKDFETRELEVKFDGHEPH-TVTHSRLVGWNPLNVQ---PDTLLFTSLIQKIKNS--TTPVMVHCIDGISRSAAFASMIiGYQLVIQSLGSV
|. .|| |...|.| . .. . .| . | | | | . . .|. .. ..||.|.| |..|| || . .. |
vsllskeefadytkrklklskakkaderivrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaid.avlerlkkekvv
KLEAVVSYIRSQRAMAITSALELAFVDAGIVKLLGLFV
. |. .| .| |..| || | | | .
dvfkvikvlrkdrphavesleqyvfvyeiilkaldsve
|
|||||||||
| subfamily_PTPN9_pd | Subfamily PTPN9 | 818-1039 | 1.7e-16 | 55.1 | In-house | 53-282 (297) | alignment | ||
Range on Protein: 818-1039
Range on HMM: 53-282/297.0
LVMDTRVVLKDYGTLFNDDYIHANRVTCSHGLQ-LILSQAPqeangesCESTIESYWWTAKQEKSTQLVMMCDFDEKcpgKTNSCARYYPESVGESMKFK
. .|||||. . |||.|| | . . .| | | . |.. .| ... .||. . |. . |..|.|.. ..|..|
cydetrvvlakvdedeasdyinanfvdGykqkkafiatqGp.......lkktvsdfWrmvWeqevlvivmttrvver...grlkcgqyWpleeessaefg
NLTVECKSKIAEKDFETRELEVK-FDGHEPHTVTHSRLVGWNPLNVQPDTLLFTSLIQKI-----------------KNSTTPVMVHCIDGISRSAAFAS
.|.|. . |.|...| ||.| . .| .||| ....| | .. . ...|. . | |..||| || |. .|..
dlsvsnveveeeedykvrvleiknvkteesrkvthfqflsWPdyGvPssaaslldvlekvrekqalavkelgdewkghpsgPPivvhcsaGiGrtGtfit
MIIGYQlVIQSLGSVKLEAVVSYIRSQRAMAITSALELAFV
. | . ....| |.. .|...|.||| .| .|
ldicls.rleevgtvdvvetvkllrtqrafsiqtpeqyefc
|
|||||||||
| 0049772 | (Phosphotyrosine protein) phosphatases II | 811-1036 | 2e-16 | 56.1 | In-house | 49-269 (314) | alignment | ||
Range on Protein: 811-1036
Range on HMM: 49-269/314.0
KQRLPIPLVMDTRVVLkDYGTLFNDDYIHANRVTCShgLQLILSQAPQEangesceSTIESY----------WWTA--KQEKSTQLVM------------
|.| . | .|.||.| .. .. |||.|. | . |. | .|.| | |.... | . .. .||
knryldilpadnrvil.pglpvsgsdyinasyvdgf..lkfIatqgple.......itvvdfreepvlyyngwrmvlrgdlnvrdivmsrdevladelsr
---------MCDFDEKCpgktnscaryypeSVGESMKFKNLTveckskiaekdfetrelEVKFDGHEPHT--VTHSRLvGWNPlNVQPDTLLFTSLIQKI
...|.. . . ...| |. .|.. . ... |. . . .|.. | .... |
LdaAlgKtpllildgng.............neptaadlellk.................eelydpelferlgikylri.pvpD.gsaplledfdeflefi
KN--STTPVMVHCIDGISRSA--AFASMIIGYQlviqslgSVKLEAVVSYIRSQRA-----MAITSALEL
.. .|| ||| .|..|.. ..| ... .. | || .....|..| .| . ...
eeadkggpvlvHCkaGkgRtgtfvvaaylmkll.......gvsleealedvrlkRpinpnpgfieqleqy
|
|||||||||
| subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 819-1032 | 5.7e-16 | 53.1 | In-house | 52-278 (301) | alignment | ||
Range on Protein: 819-1032
Range on HMM: 52-278/301.0
VMDTRVVLKDYGT--LFNDDYIHANRV-TCSHGLQLILSQAPqeangesCESTIESYWWTAKQEKSTQLVMMCDFDEKcpgKTNSCARYYPESVGESMKF
. | |..|| . | . .|| |. . .|. . | .|.| ..|. .| ||| ...||... .|. . ..| .|.|.| || .|
yddnriilkpkpnldlcqreyinasyidgysekkkfiaaqgp.......mkktlvdfWrliwqekpvsivmvtnlkeg...tkskceqywpnseaeseef
KNLTVECKSKIAEKDFETRELEVKFD-GH---------------EPHTVTHSRLVGWNPLNV--QPDTLLFT---SLIQKIKNSTTPVMVHCIDGISRSA
..||. ... . || |.| || | ....|. .. | | .| | | .... | . ||.||| |..|||
gpftvtlvneqvyPdfvirqlnvkiqdgsnngyierkfkvksdksswdvlqlqvtdWpqdGvvreprtvLqviddvihrqqkigggpvvVHCSdtVsrsG
AFASMIIGYQLViQSLGSVKLEAVVSYIRSQRAMAITS
. |. || . .. | | . |. .| .. |.|
vYcsvsiglEQc.kaegVVdvfqvtkavrrskpgaVtT
|
|||||||||
| 0043147 | (Phosphotyrosine protein) phosphatases II | 835-1033 | 9.3e-16 | 53.5 | In-house | 5-147 (172) | alignment | ||
Range on Protein: 835-1033
Range on HMM: 5-147/172.0
DDYIHANRVTCSHGL-QLILSQAPqeangesCESTIESYWWTAKQEKSTQLVMMCDFdekcpgktnscaryypesvgesmkfknltveckskiaekdfet
.|||.|. . ... ..| |.| . .|....| |... | .|.....
sdyinasyldlyyipdrfiatqgp.......lrntladfwrmlkelgithivnltel...........................................
releVKFDGHEPHTVTHSRLVGWNPLNVQpDTLLFTSLIQKIKN-----STTPVMVHCIDGISRSAAFASMIIGYqlviqslGSVKLEAVVSYIRSQRAM
.. .. ... . ..| .|. .. |. .... |.. . || ||| |..|..... . . . ...|| .|...|..| .
....lydpellerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml.......lglsleeavalvrekRpg
AITSA
|...
avqnp
|
|||||||||
| subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 822-1039 | 1.8e-15 | 51.8 | In-house | 58-263 (288) | alignment | ||
Range on Protein: 822-1039
Range on HMM: 58-263/288.0
TRVVLKDYgtlfNDDYIHANRVTCSHG-LQLILSQAPQeaNGescesTIESYWWTAKQEKSTQLVMMCDFDEKcpGKTNScARYYPESVGESMKFKNLTV
||| |.| | ||.|| |.... .|| .||| || ||| .| .. .||.|.. || || .| | |.| .||..... |
trvklsdd....pdfyiaanvvssakykrrlicaqaPl..ng.....tieelWkmllesdveyivmlcellek..Gkeks.aeyfPsklGekarigrlct
ECKSKIAE--KDFETRELEVKFDGHEPHTVTHSRLVGWNPLNVQPDTLLFTSLIQKIKNSTTPVMVHCIDGISRSAAFASMIIGYQlVIQSLGSVKLEAV
| | |. | . | .. |.|. | . | |. | . | . |.. .|. . |..||. |. |..... ..| . .... . .. .
vvkkkradidklvkvsllriskegeekvivkilhlleWdddgvPenylsplrllevlkslqkPivvhssaGvGrtgtlililiale.slrlddflgirsl
VSYIRSQRAMAITSALELAFV
.. | .| ||.. .|
laklreerfkaiqtemqylyv
|
|||||||||
| 0051082 | (Phosphotyrosine protein) phosphatases II | 835-1032 | 9.8e-15 | 49.9 | In-house | 3-138 (151) | alignment | ||
Range on Protein: 835-1032
Range on HMM: 3-138/151.0
DDYIHANRVTCShglqLILSQAPQEangescestieSYWWTAKQEKSTQLVMMCDFDEKCpgktnSCARYYPESVgesmkfknltveckskiaekdfetr
.|||....|| |..|..| . .. . |... . |.... .| |..|.||
sdyinfsyvtgg....lyrsggpla...........dflellkelgiktivnlrseeerg.....ycpeylpelg.........................
elevkfdghepHTVTHSRLVGWNPLNVQPDTLLFTSLIQKIKNS-TTPVMVHCIDGISRSAAFASMIIGYQLviqslgsVKLEAVVSYIRSQRAMAITS
..|.| ...| . ... . . ...... . || ||| |..|..... ... .. | ||......|..| .....
...........ievlhipildwpdpglplsfdavleflellldkkngpvlvHCsaGkgRTGtlvalylmllg.......vsleealeeyrlkrpgvvqp
|
|||||||||
| PTPc_DSPc_SM00012 | 947-1040 | 1.7e-14 | 49.3 | In-house | 1-100 (105) | alignment | |||
Range on Protein: 947-1040
Range on HMM: 1-100/105.0
TVTHSRLVGWNPLNVQPDTLLFTSLIQKIKNSTT------PVMVHCIDGISRSAAFASMIIGYQLVIQSLGSVKLEAVVSYIRSQRAMAITSALELAFVD
||.| || .| .. ...|....|.... ||.||| .|..|.. |. . | .| . .. ..|... .|...|.||. .... . |.
tvkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylfly
|
|||||||||
| subfamily_PTPN1_pd | Subfamily PTPN1 | 822-1045 | 2.2e-14 | 47.9 | In-house | 47-269 (290) | alignment | ||
Range on Protein: 822-1045
Range on HMM: 47-269/290.0
TRVVLKDYGTlfndDYIHANRVTCSH-GLQLILSQAPqeangesCESTIESYWWTAKQEKSTQLVMMCDFDEKcpgKTNSCARYYPESVG-ESMKFK--N
.|..|.. . ||| |. | . . ||.| | .|.. .| ..|| .||. . || ... ||.|.|. ...... .
srikleradn....dyinaslveleeakrsyiltqGP.......lpntvdhfWqmvWeqkskavvmlnkvvek...eqikcaqywPqgeeekellledtk
LTVECKSKIAEKDFETRELEVKF-DGHEPHTVTHSRLVGWNPLNVQPDTLLFTSLIQKIKNST------TPVMVHCIDGISRSAAFAsMIIGYQLVIQSL
|.|. |. .. . | ||.. .| ....| . |. . | | ....|...| |...|| || || .|. .. . |.
lkvkliseerksyytvrllelenlktqetreilhfhyttwpdfgvpespaaflkflfkvresGslssdvGpavihcsaGiGrsGtfc.lvdtclvliekk
GS---VKLEAVVSYIRSQRAMAITSALELAFVDAGIVK
. |... |. .|..| | | | | |..
ddlssvdikkvllelrkyrlGliqtadqlrfsylaile
|
|||||||||
| subfamily_PTPRA_pd | Subfamily PTPRA | 811-1039 | 2.4e-14 | 47.9 | In-house | 61-287 (330) | alignment | ||
Range on Protein: 811-1039
Range on HMM: 61-287/330.0
KQRLPIPLVMD-TRVVLKDYGTLFNDDYIHANRVTCSHG-LQLILSQAPQEangesceSTIESYWWTAKQEKSTQLVMMCDFDEKcpgKTNSCARYYPES
|.|.. | | .||.| . ||| | . . . | .| |.| |.| .| . ||. .||. ...|. | . ||.|.|.
knrvvnilPydfsrvilsvkeGveesdyinasfidGykekdkfiaaqGPke.......etvedfwrmiweqksativmltelker...keekcaqywPde
vgESMKFKNLTVECKSKIAEKDFETRELEVK--FD---GHEPHTVTHSRLVGWNPLNVQPDTLLFTSLIQKIKN----STTPVMVHCIDGISRSAAFASM
.. . |..|| . . .|. |.. |. | ... |. . .| . | .. .|..|.|. |. |..||| |. |. .| .
..GlvtyGnirvevedetvlvdytvrkflvqqlpdatrekksrlvrqfhftswPdvGvPfepiGmlkllkkvkklnqqsagpivvhcsaGvGrtGtfivl
IIGYQlVIQSLGSVKLEAVVSYIRSQRAMAITSALELAFV
. ... . | . .|. .| ||. . . |.
davle.rvkaerkvdvfefvkrlrlqrpqmvqtdeqyefi
|
|||||||||
| subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 820-1027 | 2.8e-14 | 47.8 | In-house | 46-239 (267) | alignment | ||
Range on Protein: 820-1027
Range on HMM: 46-239/267.0
MDTRVVLKDYgtlfNDDYIHANRVTCS-HGLQLILSQapqeangESCESTIESYWWTAKQEKSTQLVMMCdfdekcPGKTNSCARYYPESVGESMKFKNL
||||.|.. ...|| | | . . ..|. | .. . || .. ...| . |.. . |. ...| .|.. |...|
ddtrvilrtk....eeeyinasyvegyktknafivtq.......dplkntitdfltvihdqkvpvivllt......kvftdnirlfwPPkmgqakkyqdl
TVECKSKIAEKDFETRELEVKFDGHEPHTVTHSRLVGWNP-LNVQPD-TLLFTSLI-QKIKNSTTPVMVHCIDGISRSAAFASMIIGYQLViQSLGSVKL
||| . |.|.. ||.|| | || || | .| || | ....| |..|.| ||. || .| . . . . | ...
tvehslekeendyqiitlelkfknesahnvtlyyykkwnintnnkpylkplfgilaknqlengnrPlvvacsdGvGrsGtflvidsqlera.ktegvsdi
EAVVSYIRSQRA
. |||||
fdflrkirsqri
|
|||||||||
| subfamily_PTPRK_pd | Subfamily PTPRK | 807-1039 | 3.7e-14 | 47.3 | In-house | 42-269 (314) | alignment | ||
Range on Protein: 807-1039
Range on HMM: 42-269/314.0
SEQMKQRLP-IPLVMDTRVVLKDYGTLFNDDYIHANRVTCSH-GLQLILSQAPQeangescESTIESYWWTAKQEKSTQLVMMCDFDEKCpgkTNSCARY
...|.| | .||.|. . ||| |. . . . | | | ..|.. .| .|... .||. .. |. | .|
enreknrsgdilaydrsrvflitidgdpssdyinaalidsykrpaafivtqgPl.......qetvkdfWrlvydencasivmltelvevg...rvkClky
YPEsvgESMKFKNLTVECKSKIAEKDFETRELEVKF---DGHEPHTVTHSRLVGWNPLNVQPDTLLFTSLIQKIKNST----TPVMVHCIDGISRSAAFA
.|| ........ ||. . ..... .| . |. .| ..| . . .|| .| . .|....|.|. ...||| | |. .|
WPe...dtevygdikvelvetellaelvvrifrveklargqeeirevrqfqflgWpdhdvPvsatgllklvrrvkksqeeeaGrivvhCsaGaGrtGtfi
SMIIGYQLvIQSLGSVKLEAVVSYIRSQRAMAITSALELAFV
. | .. |. | | . .| .||.. . |.
aidivldm.ieregvvdvfnavktlrsrkvnmveteeqykfi
|
|||||||||
| 0046846 | (Phosphotyrosine protein) phosphatases II | 833-1038 | 3.7e-14 | 48.4 | In-house | 10-164 (176) | alignment | ||
Range on Protein: 833-1038
Range on HMM: 10-164/176.0
FNDDYIHANRVTCSHglqlilsqapQEANGESCESTIESYWWTAKQEKSTQLVMMCDFDEKCPGKtnsCARYYPESVGESMkfknltveckskiaekdfe
.. |||.|| . .|. | .....|..... |... | .|.... |. | |..|.|| ....
ldldyinanlilgsr..........piatqgplprtladflemlkelgitavvnlteevelgrlk...cpnywpeleklgi...................
trelevkfdghephTVTHSRLVGWNPLNVqPDTLLFTSLIQKIKNSTTPVMVHCIDGISRSAAFASMIigyqlVIQSLGSVKLEAVVSYIRSQRA-MAIT
.. | . .. . . | . .|.. .. || ||| ||.|..... . ... ...| .....|.|| .|..
..............qylhlpwpDhgvpdl.elllellefirealkeggpvlVHCsaGigRtgtlvaay.....llelekglsveealalvreqRplgavq
SALELAF
. . |
tpeQyrf
|
|||||||||
| 0036282 | (Phosphotyrosine protein) phosphatases II | 835-1033 | 6.6e-14 | 47.4 | In-house | 2-156 (174) | alignment | ||
Range on Protein: 835-1033
Range on HMM: 2-156/174.0
DDYIHANRVTCSHGL-QLILSQAPQEangescestiesYWWTAKQEKSTQLVMMCDFDEkcpGKTNSCARYYPEsvgesmkfknltveckskiaekdfet
.|||.|. . |. . ||..|.| . .| |....| .||... | . | .|.||
sdyinaspldlsyitprliagqgpla............fwemlkelgittvvmlleeke...lglykcinywpe..........................
relevkFDGHEPHTVTHSRLVGWNPLNVQPDTLlFTSLIQKIKNS-----TTPVMVHCIDGISRSAAFASMIIGYQLVIqsLGSVKLEAVVSYIRSQRAM
. .. ... . ..| .| ... . .... ... || ||| |..|..... . . ... . . |. ..| .|.|| .
......lredlerlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll..eslvdaldlvrelRlqrpg
AITSA
....
mvqtp
|
|||||||||
| subfamily_eak_pd | Subfamily eak | 862-993 | 1.7e-13 | 44.7 | In-house | 99-225 (332) | alignment | ||
Range on Protein: 862-993
Range on HMM: 99-225/332.0
GESCESTIESYWWTAKQEKSTQLVMMCDFDEKcpgKTNSCARYYPESVGESMKFKNLTVECKSKIAEKDFETRELEVKfDGHEPHTVTHSRLVGWNPLNV
| . |. . .| ..|| .|.. . |. | . .|.|. | .|| | ||.|. . .. .||| ||.. | | | | | .. || ...
Giasedkvfafwqmvleqkspaivqlledvel...kleksdkyfpdktreelkfGildverkefvkrniletrllels.kGnethrvlhykvfGwtettl
qPDTLLFTSLIQKIKNSTTPVMVHCIDGISRS
| | .| . .|. .. .. . . .|
.pkyedflalrkvmkevGvlllivmksallss
|
|||||||||
| subfamily_PTPN14_pd | Subfamily PTPN14 | 820-1046 | 5e-13 | 43.7 | In-house | 62-295 (300) | alignment | ||
Range on Protein: 820-1046
Range on HMM: 62-295/300.0
MDTRVVLKDYGTLfNDDYIHANRVTCSHGLQ---LILSQAPQeangescESTIESyWWTAKQEKSTQLVMMCDfDEKCPGKTNsCARYYPES--VGESMK
|.|| |. ...|| | .. | | . | .|.|. | |.. .| |. .||..| .|. ||. . .|.|.. ....
ednrvelsptken.stgyinassikvsvggkersyivaqgPl.......eltvqd.fWqmvWeqgvqlivmlt.eeeedgkek.sfkyfPkleskkktve
FKNLTVECKSKIAEKDFETRELEVKF-DGHEPHTVTHSRLVGWNPLNVQPDTLLFTSLIQKIK-------------NSTTPVMVHCIDGISRSAafasMI
|.. | | . . . |. |..|. .| || | . . | .| .| | | ..... .| ||.||| .|. |. ..
fgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseveskeskPPvlvhCsaGvGrtG....vl
IGYQLVIQSL---GSVKLEAVVSYIRSQRAMAITSALELAFVDAGIVKL
| .|.|..| ..... |.. .| || . . . || ..|
ilsdlliatlehneeidikkvlarLreqrmllvqtlaqYkfvYkvliky
|
|||||||||
| 0049260 | (Phosphotyrosine protein) phosphatases II | 867-1033 | 1e-12 | 43.5 | In-house | 20-136 (152) | alignment | ||
Range on Protein: 867-1033
Range on HMM: 20-136/152.0
STIESYWWTAKQEKSTQLVMMCDFDEkcpGKTNSCARYYpesvgesmkfknltveckskiaekdfetrelevkfdghephtvtHSRLVGWNPLNVQPDTL
|....| |. . | .||.....| . |..|. . . | .|....
ntladfwrmlkelgittivmltelle...lgklkceqyi............................................qylhlpwpDhgvpdlsq
LFTSLIQKI----KNSTTPVMVHCIDGISRSAAFASMIIGYqlviqslGSVKLEAVVSYIRSQRAMAITSA
|. |.. | ... || ||| |..|..... . . . |.|| .|...|..| .|...
lllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml.......lgvsleeavalvrekRpgavpnp
|
|||||||||
| subfamily_PTPRN_pd | Subfamily PTPRN | 811-1040 | 1.4e-12 | 42.0 | In-house | 59-285 (297) | alignment | ||
Range on Protein: 811-1040
Range on HMM: 59-285/297.0
KQRLPIPLV-MDTRVVLKDYGTLFNDDYIHANRVTCSHGLQL--ILSQAPqeangesCESTIESYWWTAKQEKSTQLVMMCDFDEKcpgKTNSCARYYPE
|.| | ..|| ||. . ..||| | .. . . | .|.| ||. ..| . .. .. .|... .|. .. |.||.|.
knrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgp.......lastvadfwqmvweqGvvvivnltrleee...gvkqckrywpd
SVGESMKFKNLTVeCKSKIAEKDFETRELEVK-FDGHEPHTVTHSRLVGWNPLNVQPDTLLFTSLIQKIK----NSTTPVMVHCIDGISRSAAFASMIIG
| .. .. . .| .|. | . .| .. .| ||| . |. .| . . . . .|. ..|..||| || |. .. . .
eGsevyhiyevhl.vsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrGrscpivvhcsdGaGrtGvyilidlv
YQLVIQSLGSVKLEAVVSYIRSQRAMAITSALELAFVD
. ... . . . | . ..| ||. . . .. |.
lnrllkGvkeidiaatlehlrdqrpglvktkdqfefal
|
|||||||||
| subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 833-1039 | 4e-12 | 40.2 | In-house | 59-280 (302) | alignment | ||
Range on Protein: 833-1039
Range on HMM: 59-280/302.0
FNDDYIHANRVTCsHGLQLILSQAPQEANG----E------SCESTIESYWWTAKQEKSTQLVMMCDFDEkcpGKTNSCARYYPESVGESMKFKNLTVEC
|..|.| || .. ... |..| | . . ||.| .| .| . . | .|.| | .. . || || . ||. .||.. ||.
fkndfinanvlkl.deikwimaqGpmdGtekkekvskkpivpkkstlekhwalieqynvaivvqlcsfve...deekkcaeyysdkvggelkfgrytvkt
K---SKIA----EKDFETRELEVKFD---GHEPHTVTHSRLVGWNPLNVQPDTLLFTSLIQKIKNSTTPVMVHCIDGISRSAAFASMIIGYQLVIQSLgS
. ... |.| .|.| . . ..|| .| .. ... . . |.||| |. |. .. .. | || .
vsvktdleeftdkksfklytveiknekkkkkvkktvdilafsawpdhGapkeaytaldilkfcesykknvlvhcsaGvGrtGtlvaikyGiqlcskkk.v
VKLEAVVSYIRSQRAMAITSALELAFV
.| .| .|. | |. .. | ..
tdllsivlpvrqcryGavqdeqqliyl
|
|||||||||
| subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 822-1045 | 3.9e-11 | 38.0 | In-house | 40-253 (284) | alignment | ||
Range on Protein: 822-1045
Range on HMM: 40-253/284.0
TRVVLKDYGTLFNDDYIHANRVTCSHGL-QLILSQAPQeangescESTIESYWWTAKQEKSTQLVMMCdfdekcpgkTNSCARYYPESVGESMKFKNLTV
..| |. ||| | .| . | .| |. . |.. .| . ... .|.. . |..|.| . . . .. |
nvvklerliGeefsdyinasfitGyqrkdkyiatqGPl.......dntladfWrmiweyncstivllt.........kdkcsqywplkivikeerfkvkv
ECKSKIAEkdFETRELEVKFDGHEP--HTVTHSRLVGWNPLNVQPDTLLFTSLIQK------IKNSTTPVMVHCIDGISRSAAFASMIIGYQlVIQSLGS
. .. .| . |..|. ||.| ... . || | . . |..| .| ....||| |. |. .. . . . ..
dsveesee..yvvrdielsedgkekdirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrtgvyivldvlld.rmkeekq
VKLEAVVSYIRSQRAMAITSALELAFVDAGIVK
| . .| .| || . . . |. . ...
vdvynfvrdlrqqrntlvqdlvqykfiysalle
|
|||||||||
| subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 866-1039 | 4.5e-11 | 37.2 | In-house | 102-271 (315) | alignment | ||
Range on Protein: 866-1039
Range on HMM: 102-271/315.0
ESTIESYWWTAKQEKSTQLVMMCDFDEkcpGKTNSCARYYPESvgeSMKFKNLTVECKSKIAEKDFETRELEVKFdGHEPHTVTHSRLVGWNPLNVQPDT
.... .| .|. ...||. . | |. . . .|.|. . . ..|| ||. .... | | | | | . ..| .. | .| |
vasvkdfwrlvfeedigkivmltnlve...gekrkaekywpdk...kviyGkitvtrkseevnteytvrtlsvvf.gdnirevvqlhytswpdmgvpkyt
LLFTSLIQKIK----NSTTPVMVHCIDGISRSAAFASMIIGYQlVIQSLGSVKLEAVVSYIRSQRAMAITSALELAFV
. . ||...| || ....||| .|. |. .| .. . .. . . .. .|..| .. .| . |.
iplmnlirtvkqhhtnsvgaivvhcsaGvGrtGtfitldavld.qaeaenaidvynfitgvrqnrikmvqvaeqyqfi
|
|||||||||
| subfamily_PTPRG_pd | Subfamily PTPRG | 820-1044 | 6.2e-11 | 36.2 | In-house | 60-284 (563) | alignment | ||
Range on Protein: 820-1044
Range on HMM: 60-284/563.0
MDTRVVLKDYGTLFND-DYIHANRVTC-SHGLQLILSQAPqeangesCESTIESYWWTAKQEKSTQLVMMCDFDEKcpgKTNSCARYYPEsvGESMKFKN
.|| |.. .. ||| || . .. . | .| | ..|.. .| ..... .||. .. |. . . | .|.|. ||.....
drsRvklsplpgkkkklDYinAnyidGyqkskafiatqgp.......lkdtfddFWrmiWeqnvaiivmitnlver...grrkcdvYWPk..desetyga
LTVECKSKI-----AEKDFETRELEVKFDGH--EPHTVTHSRLVGWNPLNVQPDTLLFTSLIQKIKN----STTPVMVHCIDGISRSAAFASMIIgYQLV
|.| ... ... . ..|..| . . ..|.. . | .| .| . ..| . . |..||| |..|. . .
lqvtlieeevlalytvrtlviknlklkkkkqcdteklvrqyhytkWPdhgvPehslpvLifvkkssaankaeaGPivvHcsaGvgrtGtyivldt.llkq
IQSLGSVKLEAVVSYIRSQRAMAITSALELAFVDAGIV
||. .| . .. ||.|| . ... . |. ..
iqqenavnvfgflkhiraqRnflvqteEqYiflhdall
|
|||||||||
| 0048076 | (Phosphotyrosine protein) phosphatases II | 946-1032 | 7.3e-11 | 37.4 | In-house | 45-128 (145) | alignment | ||
Range on Protein: 946-1032
Range on HMM: 45-128/145.0
HTVTHSRLVGWNPLNVQPDTLLFTSLIQKIKNS---TTPVMVHCIDGISRSAAFASMIIGYQlviqsLGsVKLEAVVSYIRSQRAMAITS
..... ..| .|.... |. .... |.. || ||| |..|..... . . .. || | || .. ..|||| .|...
rlgiqylylpwpDhgvpdllellleflefieealkeggpvlVHCsaGvgRtgtlvaaylmll.....lg.vsleealelvrsqrpgavpn
|
|||||||||
| subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 822-1045 | 8.4e-11 | 36.7 | In-house | 76-289 (319) | alignment | ||
Range on Protein: 822-1045
Range on HMM: 76-289/319.0
TRVVLKDYGTLFNDDYIHANRVTCSHGL-QLILSQAPQeangescESTIESYWWTAKQEKSTQLVMMCdfdekcpgkTNSCARYYPESVGESMKFKNLTV
..| |. ||| | || . | .| |. . |.. .| . ... .|.. . |..|.| . . . .. |
nvvklerliGeefsdyinasfvtGyqrkdkyiaaqGPl.......dntladfWrmiweyncstivllt.........kdkcsqywplkivikeerfkvkv
ECKSKIAEkdFETRELEVKFDGHEP--HTVTHSRLVGWNPLNVQPDTLLFTSLIQK------IKNSTTPVMVHCIDGISRSAAFASMIIGYQlVIQSLGS
. . || . |..|. ||.| .| . || | . . |..| .| ....||| |. |. .. . . . ..
dsveetae..yvvrdielsedgkekdirkitqfhflGwpdvGvpdypsdlmrlvkkvrhltskenhranivvhcsaGvGrtGvyivldvlld.rmkeekq
VKLEAVVSYIRSQRAMAITSALELAFVDAGIVK
| . .| .| || . . . |. . ...
vdvynfvrdlrqqrntlvqdlvqykfiysalle
|
|||||||||
| subfamily_ptpA1_pd | Subfamily ptpA1 | 817-1002 | 1.2e-10 | 35.7 | In-house | 57-252 (418) | alignment | ||
Range on Protein: 817-1002
Range on HMM: 57-252/418.0
PLVMDTRVVLKDYGTLFNDDYIHANRVTCSHGLQLILSQAPQeangescESTIESYWWTAKQEKSTQLVMMCDFDEKCPGKtnsCARYYPESVGES----
| ||| || ||| || . .. |.| .| | || .| ... .||. |.| | | ||.|| .|
lpvnhtrvqlkkiqdkegsdyinanyidgaypkqfictqgpl.......pntiadfwrmvwenrcriivmlsresencrik...cdrywpeqiggeqfsi
-----MKFKNLTVECKSKIA--EKDFETRELEVKFDGhEPHTVTHSRLVGWNPLNVQPDTLLFTSLIQKIKNS----------TTPVMVHCIDGISRSAA
| .|| | |.. ||.. . |.| | . .|. . || |. | | |.. | | |..||| |. |. .
ygngnevfgtysvelveviqdpereiitrnirltfeg.etrditqyqyegwpdhnipdhtqpfrqllhsitnrqnqiipssdrnvpiivhcsagvgrtgt
FASMIIG
|.. .|
fctavim
|
|||||||||
| 0048179 | (Phosphotyrosine protein) phosphatases II | 944-1033 | 1.5e-10 | 36.5 | In-house | 48-131 (144) | alignment | ||
Range on Protein: 944-1033
Range on HMM: 48-131/144.0
EphtVTHSRLVGWNPLNVQPDTLLFTSLIQKIKNS---TTPVMVHCIDGISRSAAFASMIIGYqlviqSLGsVKLEAVVSYIRSQRAMAITSA
| ... ..| .| ... |. .... |.. || ||| |..|..... . . . || . || .. ..||.| .|...
e...giqylhlpwpDhgvpdllellleflefieealeeggpvlVHCsaGvgRtgtlvaaylmk.....klg.lsleealalvrsrrpgavpnp
|
|||||||||
| subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 820-961 | 2.4e-10 | 34.7 | In-house | 46-179 (297) | alignment | ||
Range on Protein: 820-961
Range on HMM: 46-179/297.0
MDTRVVLKdyGTLFNDDYIHANRVTC---SHGLQLILSQAPQEAngescesTIESYWWTAKQEKSTQLVMMCDFDEKcpGkTNSCARYYPESVGESMKFK
|||| |. .. . ||| |. |. . |. ||.| | .| |.. .| .. .||.. . | | . || |.|..|.| .|
ddtrvkll..rviterdyinadyvvfpdeeadlkyilaqGplsa.......tvddfwtlvaeqdvrvivmvaklqed..G.rdkcapywpsvvqerlkag
NLTVECKSKIAEKdFET---RELEVKFDgHEPHTVTHSRLVGWNPLNV
.. || |. ... |.. ||.. . | |.| . ..| |
dvvveflsstsde.fdrviltelqliyr.sesrvvrhvqflswpdhGv
|
|||||||||
| subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 806-1037 | 1.4e-09 | 31.8 | In-house | 49-275 (302) | alignment | ||
Range on Protein: 806-1037
Range on HMM: 49-275/302.0
KSEQMKQRLPIPLVMDTRVVLKDYGtlfNDDYIHANRVTCS-HGLQLILSQAPQEangeSCESTIESYWWTAKQEKSTQLVMMCDFDEkCpgkTNSCARY
|.. |.. . ..|...| .. .|.|..| .|. . ..||.| |. . |. .|..| . ||| ...|.. .| . ... .
kknlkknqsedvpildsnlvkleae...pdsyvnaskvevPeltrsiilaQlpkv....dsedsveeFWrmvfqekivsvvilvgeee.l...kktlsel
YPESVGESMKFKNLTVECKSkIAEKDFET--RELEVKFDGHEPHTVTH-SRLVGWNPLNVQPDTLLFTSLIQKI----KNSTTPVMVHCIDGISRSAAFA
.|. |. ..... | . . ... |. .|| .| .. | |.. .| . ..|. ... .... |. | .||
fpkksgdykeygkmfvNnrk.VekaeeektryviEvlPegcsnsvlanvyvltnWkqkkvpvkyaeliktaakvfakkikadentvivSknGaGRagafl
SMIIGYQLVIQSlGSVKLEAVVSYIRSQRAMAITSALELA
.... . . .. .. . .| |||||. |. |. .
tlavaveklqkg.kepnikeivksiRsqRpravdslkQyv
|
|||||||||
| subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 821-999 | 8.1e-09 | 30.0 | In-house | 17-192 (237) | alignment | ||
Range on Protein: 821-999
Range on HMM: 17-192/237.0
DTRVVLKDYGTlfNDDYIHANRVTCSHGLQ--LILSQAPqeangesCESTIESYWWTAKQEKSTQLVMMCDFDEkcpGKTNSCARYYPESvGESMKFKNL
.||||| |. . ||| |. . | | .| | ||. . .| ||| . .||. . | |. | .|.|.. . . |
hsrvvlkgags..gsdyinatylkgfdgtpkkyiaaqgp.......lesscddfwqmvwqekcsvivmltglie...gnelkchkywpst.dqpaaygvl
TVECKSKIAEKDFETRELEVKF--DGHEPHTVTHSRLVGWNPLNVQPDTLL---F-TSLIQKIKN--STTPVMVHCIDGISRSAAFASM
|| | | . |. | | . .| . .. | | | | .|.. . ..| ..|| |. |.. | .
tvslkkkeefsdytvrslllskrltlkevrlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvi
|
|||||||||
| subfamily_CG7180_pd | Subfamily CG7180 | 821-1035 | 1e-07 | 25.9 | In-house | 56-278 (296) | alignment | ||
Range on Protein: 821-1035
Range on HMM: 56-278/296.0
DTRVVLKDYGTLFNDDYIHANRVTC-SHGLQLILSQAPQeangescESTIESYWWTAKQEKSTQLVMMCdfdeKCPGKTNSCARYYPESVgeSMKFKNLT
.||||. . ..||| | | . . | .||. ..|....| .|.. .|... | . .. . |.|. .....
ynRvvLekldGeeksdYinavyvdsflkkkeyivteapk.......ketvdefWrlvydeeisavvvLt....ktfdfakmypsywpnks..keqygeif
VECKSKIAEKDFETRELEVKFD-----------GHEPHTVTHSRLVGWNPLNVQPDT-LL---FT----SLIQKI--KNSTTPVMVHCIDGISRSAAFAS
|| .. ....|.. .. | .|.. .| |. . | . ....|. .. . ||.|.. || ||| .. .
veiveekqyanlkirtfkltkkivalteqekqvkaetRivklfqlteWeledkvPlstnalielrrrvrlwrekvdedpeegPvvvvssdGasRsGvyla
MIIGYQLVIQSlGSVKLEAVVSYIRSQRAMAITSALE
. . .||.. . | . | .| .| . . |
idanlelveke.eevdvFeavktlrrsRpqLvenvee
|
|||||||||
| subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 836-1000 | 6.9e-07 | 23.3 | In-house | 68-233 (312) | alignment | ||
Range on Protein: 836-1000
Range on HMM: 68-233/312.0
DYIHANRVT-CSHGLQLILSQAPQEangesceSTIESYWWTAKQEKSTQLVMMCDFDEKCpgkTNSCARYYPESVGES--MKFKNLTVECKS-KI--AEK
||||| | |.. ... .|.| | .|. .| | || ....| | | .. ||.| . || . | | .| |
fyihanfvkictkperfvctqgple.......ntcthfwqlalslgstsiillcgfvedg...sekcakyisdivgfvdledhrvyteycteieiggksk
DFET-R--ELEVKFDGHEPhTVTHSRLVGWNPLNVqPDTL-LFTSLIQKIKNSTTPVMVHCIDGISRSAAFA---SMI
| | | . || | | . | . | . ||. |. .|. ||. || |. |. ..| |||
dkithrvlkvvvkatgqes.klnhyqwaswpdhgm.pdscdtalrllsavkkdkkpviahcsagvgrtgtlaliesmi
|
|||||||||
| subfamily_CG42327_pd | Subfamily CG42327 | 798-976 | 7.2e-07 | 23.2 | In-house | 23-191 (319) | alignment | ||
Range on Protein: 798-976
Range on HMM: 23-191/319.0
EVPGREALKSEQMkQRLPIPlvmDTRVVLKDYGTLFNDDYIHANRVTCSHGlqlilSQAPQEANGESCESTIESYWWTAKQEKSTQLVMMCDFDEKCpgk
||| || . . .|.| .|||||. | .| |..|. | . ... | | |.. ..| | . .| .| ..| |.
evPvtskdksrvi.nvvPlP...etrvvlqrigdddkdeyldasyvrGydd.....apnsyiaaqvsledsssdfwrtvweqqsrvivqltdlselG...
TNSCARYYPESVGE--SMKFKNLTVECKSKIAEKDFETRELEVK-FDGHEPHTVTHSRLvGWNPLNVQPDTLLFTSLIQKIK
. ||.|.| . . . .. | | . ... . . | .| |..| .|| | .| . . ... ...
ikvcaeylPtketldntslyGdilvtlkgrevkdryaistlllkrvdkeesrelthywy.kwleaevPaeeaaliamllevr
|
|||||||||
| DSPc | Dual specificity phosphatase, catalytic domain | 969-1027 | 1.3e-06 | 23.3 | Pfam-A | 63-115 (133) | alignment | ||
Range on Protein: 969-1027
Range on HMM: 63-115/133.0
TSLIQKIKNSTTPVMVHCIDGISRSAAfasMIIGYQLVIQSLgsvKLEAVVSYIRSQRA
.. |.|.... |.||| ||||||. .|| | . ..| .|. .......|
vefiekaeqkgkkvlVHCqaGisRSat...liiaYlmktknl...slneAyefvkerrs
|
|||||||||
| DSPc | Dual specificity phosphatase, catalytic domain | 969-1027 | 1.3e-06 | 23.3 | In-house | 63-115 (133) | alignment | ||
Range on Protein: 969-1027
Range on HMM: 63-115/133.0
TSLIQKIKNSTTPVMVHCIDGISRSAAfasMIIGYQLVIQSLgsvKLEAVVSYIRSQRA
.. |.|.... |.||| ||||||. .|| | . ..| .|. .......|
vefiekaeqkgkkvlVHCqaGisRSat...liiaYlmktknl...slneAyefvkerrs
|
|||||||||
| PTPc_motif_SM00404 | 969-1009 | 1.5e-06 | 23.2 | In-house | 70-107 (140) | alignment | |||
Range on Protein: 969-1009
Range on HMM: 70-107/140.0
TSLIQKIKNSTTPVMVHCIDGISRSAAFasmIIGYQLVIQS
.. |...... . |.||| |.||||.. || | . ..
ldfienaekkggkvlVHCqaGvSRSatl...iiaYlmryrq
|
|||||||||
| subfamily_CG42327_pd | Subfamily CG42327 | 976-1039 | 2e-06 | 21.7 | In-house | 244-307 (319) | alignment | ||
Range on Protein: 976-1039
Range on HMM: 244-307/319.0
KNSTTPVMVHCIDGISRSAAFASMIIGYQLVIQSLGSVKLEAVVSYIRSQRAMAITSALELAFV
..| |..||| ||. |. . | . . .| || . .||..| .|| |. . .|.
resqGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefi
|
|||||||||
| subfamily_Slingshot_pd | Subfamily Slingshot | 971-1028 | 3e-06 | 20.7 | In-house | 88-139 (169) | alignment | ||
Range on Protein: 971-1028
Range on HMM: 88-139/169.0
LIQKIKNSTTPVMVHCIDGISRSAafaSMIIGYQLVIQslgSVKLEAVVSYIRSQRAM
|.| |.. . |.||| |.|||| | .| | . ...|| ..|....| .
fiekakkkgskvlvhckmGvsrsa...stviayamkey...glsleealeyvkerrsv
|
|||||||||
| subfamily_DSP8_pd | Subfamily DSP8 | 970-1032 | 5e-06 | 20.2 | In-house | 84-139 (159) | alignment | ||
Range on Protein: 970-1032
Range on HMM: 84-139/159.0
SLIQKIKNSTTPVMVHCIDGISRSAafaSMIIGYqlVIQSLgSVKLEAVVSYIRSQRaMAITS
. |.|.|.. . |.||. |||||| ...|.| ... | ...|. .....| .|
efidkaksengrvlvhvlaGisrsa...tvaiay..imktl.emsldeayrfvkekr.ptisp
|
|||||||||