Gene W09H1.1 in Caenorhabditis elegans

Synonym: CELE_W09H1.1, CELE_W09H1.1

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family DSP
Subfamily DSP-unclassified
Protein sequence
ID Type Fasta BLAST phosphatome Note
CeleP202_AA protein Get Run
CeleP202_AA_198-371 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
0044763 (Phosphotyrosine protein) phosphatases II 189-371 2.8e-15 51.9 In-house 13-170 (178) alignment
Range on Protein: 189-371
Range on HMM: 13-170/178.0
TNPFRSLYIDevVWQIDDVVFASAIDAVNNNSLMCRLNIEFICEIADETADHVQEarrqnrgfecpCFCNRSSSHFRYYLSYSLPETEqrcmmlteDTKL
 ...|| ||.  ...|.. .....  ....  |...|.|  |. ...|.  . ..           |.    ...   || . .|           .. |
eglersdyin..aseilpglylgslppaddlellkelgithivnlteelelgflk...........cdpywpeeagiqylhipipDhg........vpdl

NDMFDGFLDLVQRAR-RAKRNVLVCSTRGRNRAPAFASAYLMSKEQIPRQAAVAKVRtamgTMRPpVNISDFMQRKLMRYQQHL
 ..|. |......|. . ...|||. . |..|..... |||| | ... ..|.. ||     .|| ..... ..| |......|
lehflefvefieealdekggpvlVHCsaGvgRsgtlvaaylmkklglsleeaielvr....erRp.ivpnpgqlrqLyefelrl

0048076 (Phosphotyrosine protein) phosphatases II 203-363 5.2e-13 44.4 In-house 6-138 (145) alignment
Range on Protein: 203-363
Range on HMM: 6-138/145.0
QIDDVVFASAIDAVNNNSLMCRLNIEFICEIadetadhvqearrqnrgfecPCFCNRSSSHFRYYLSYSLPEteqrcmmlTEDTKLNDMFDGFLDLVQRA
.|.. .. . . ....  |...|.|  .  .                     . ..  . .   || ...|          .   | .... ||.....|
eilpglylgslptaldlellkdlgittvlnl....................tselellerlgiqylylpwpD........hgvpdllellleflefieea

RRAKRNVLVCSTRGRNRAPAFASAYLMSKEQIPRQAAVAKVRTAMGTMRPPVNISDFMQRK
......|||. . |..|..... |||| ..... . |...||..   . | ..   |... 
lkeggpvlVHCsaGvgRtgtlvaaylmlllgvsleealelvrsqrpgavpnpgqlrflyef

0048179 (Phosphotyrosine protein) phosphatases II 202-369 7.9e-13 43.9 In-house 5-142 (144) alignment
Range on Protein: 202-369
Range on HMM: 5-142/144.0
WQIDDVVFASAIDAVNNNSLMCRLNIEFICEIADETaD-HVQEARrqnrgfecpcfcnrssshFRYYLSYSLPETeqrcmmltEDTKLNDMFDGFLDLVQ
..|.. .. . . ....  |...|.|  .. ...|  . .  |                       || ...|          .   | .... ||....
seilpglylgslptaldlellkklgittvinlteey.epeflere..................giqylhlpwpDh........gvpdllellleflefie

RARRAKRNVLVCSTRGRNRAPAFASAYLMSKEQIPRQAAVAKVRTAmgtmRPPVNISDFMQRKLMRYQQ
.|.. ...|||. . |..|..... |||| |.... . |.| ||..    || ..... . | |..|..
ealeeggpvlVHCsaGvgRtgtlvaaylmkklglsleealalvrsr....rpgavpnpgqlrfLleyek

0049772 (Phosphotyrosine protein) phosphatases II 286-371 1.9e-12 43.0 In-house 193-273 (314) alignment
Range on Protein: 286-371
Range on HMM: 193-273/314.0
TKLNDMFDGFLDLVQRArRAKRNVLVCSTRGRNRAP-AFASAYLMSKEQIPRQAAVAKVRTAmgtmRPpVNISDFMQRKLMRYQQHL
. | ..|| ||.....| .....|||. . |..|.. . . ||||.. ... . |.. || .    || .|... . . |..|...|
aplledfdeflefieea.dkggpvlvHCkaGkgRtgtfvvaaylmkllgvsleealedvrlk....Rp.inpnpgfieqleqyefil

PTPc_motif_SM00404 207-367 6.1e-11 37.4 In-house 8-137 (140) alignment
Range on Protein: 207-367
Range on HMM: 8-137/140.0
VVFASAIDAVNNNSLMCRLNIEFICEIADETADHvqearrqnrgfecpcfcnrssSHFRYYLSYSLP--EteqrcmmlTEDTKLNDMFDGFLDLVQRARR
 .. . ... .|  |.  |.|... ....|   .                     ..   .   ..|  .        .| .|| . .|  || ...|..
hlylgskskaqnpallkklgithvinvteevslt.....................kensgfqilqipldd........nekdklskyldkvldfienaek

AKRNVLVCSTRGRNRAPAFASAYLMSKEQIPRQAAVAKVRTAMGTMRPpvniSDFMQRKLMRY
 ...|||  . | .|  ... ||||...|.  ..|.  |.    ...|    . .  |.|. |
kggkvlVHCqaGvSRSatliiaYlmryrqlslaeayefvkerRpiisp....nlnfvrqLiey

DSPc Dual specificity phosphatase, catalytic domain 274-355 1.2e-10 36.3 Pfam-A 49-122 (133) alignment
Range on Protein: 274-355
Range on HMM: 49-122/133.0
EteqrcmmlTEDTKLNDMFDGFLDLVQRARRAKRNVLVCSTRGRNRAPAFASAYLMSKEQIPRQAAVAKVRTAMGTMRPPVN
.        ...||. . ..   . ...|.. ...|||  . | .| .... ||||...... . |.. |.   ....| ..
d........etetkiskeleeavefiekaeqkgkkvlVHCqaGisRSatliiaYlmktknlslneAyefvkerrskispnag

DSPc Dual specificity phosphatase, catalytic domain 274-355 1.2e-10 36.3 In-house 49-122 (133) alignment
Range on Protein: 274-355
Range on HMM: 49-122/133.0
EteqrcmmlTEDTKLNDMFDGFLDLVQRARRAKRNVLVCSTRGRNRAPAFASAYLMSKEQIPRQAAVAKVRTAMGTMRPPVN
.        ...||. . ..   . ...|.. ...|||  . | .| .... ||||...... . |.. |.   ....| ..
d........etetkiskeleeavefiekaeqkgkkvlVHCqaGisRSatliiaYlmktknlslneAyefvkerrskispnag

subfamily_DSP19_pd Subfamily DSP19 283-370 3.5e-10 34.4 In-house 66-149 (152) alignment
Range on Protein: 283-370
Range on HMM: 66-149/152.0
TEDTKLNDMFDGFLDLVQRARRAKRNVLVCSTRGRNRAPAFASAYLMSKEQIPRQAAVAKVRTAMGTMRPpvniSDFMQRKLMRYQQH
...|.| ....  || .. ||...  |||    |. |..... ||||.||..  . |. .||.|  ...|     .  ...| .|...
lpetdllsylkealdFieearskdgavlvHCnAGvSRsasvviaylmkkeelsleealelvrearpcikP....neGFikqLkeyeae

0041856 (Phosphotyrosine protein) phosphatases II 264-367 5.7e-10 34.5 In-house 68-170 (182) alignment
Range on Protein: 264-367
Range on HMM: 68-170/182.0
FRYYLSYSLPETEQRCMMLTEDTKLNDmFDGFLDLVQRARRAKRNVLVCSTRGRNRAPAFASAYLMSKEQIPRQAAVAKVRTAMGTMRPPVNISDFMQRK
..|. ..   .  | . .  .|    | .| .||....... ...|||  . |..|..... |||| | ... . ||. || .   |    |   | |..
elywpellerlgiqylylpwpDhgvpd.ldelldfieevleeggpvlVHCsaGvgRtgtlvaaylmkklgvsleeavklvrsrRpgmvitpnqyfflqla

LMRY
|. .
llel

subfamily_PTPMT1_pd Subfamily PTPMT1 247-371 1.9e-08 28.9 In-house 53-168 (171) alignment
Range on Protein: 247-371
Range on HMM: 53-168/171.0
QNRGFECPCFCNRSSSHFRYylsySLPETEQRCMMLTEDTKLNDMFDGfLDLVQRARRAKRNVLVCSTRGRNRAPAFASAYLMSKEQIPRQAAVAkvrtA
 |  .|   ..| . .. ..     .   . . .  || ..|.....| ...... .  .. | |    || |. . ...||| ||..  . |.     |
lneeyelkalansteewkkl....gveqlqlatvDfteapdleklekg.vefiekvaskgkrvYvHCkaGrgRsatlvacylmkkeklspeeAlk....a

MGTMRPPVNISDFMQRKLMRYQQHL
. . |. ... .. .. | .|...|
lkkkRkiirlakkqwkalqeyeekl

0046846 (Phosphotyrosine protein) phosphatases II 288-350 3.3e-08 29.0 In-house 92-155 (176) alignment
Range on Protein: 288-350
Range on HMM: 92-155/176.0
LnDMFDGFLDLVQRARRAKRNVLVCSTRGRNRAPAFASAYLMSK-EQIPRQAAVAKVRTAMG-TM
| . .. .|.....|......|||    |..|..... |||. .  ... . |.|.||      .
l.elllellefirealkeggpvlVHCsaGigRtgtlvaayllelekglsveealalvreqRplga

0042113 (Phosphotyrosine protein) phosphatases II 287-354 1.2e-07 26.9 In-house 152-229 (245) alignment
Range on Protein: 287-354
Range on HMM: 152-229/245.0
KLN---DMFDGFLDLVQRARR--AKRNVLVCSTRGRNRAPAFASAYLM-----SKEQIPRQAAVAKVRTAMGTMRPPV
.     .... ||..|..|..  ..  ||| .. |..|. .|. ||||     .   .. . ||...|   . ...  
gvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleqlekelgvsleeavkelrsqRpgavqtp

0045450 (Phosphotyrosine protein) phosphatases II 274-351 1.3e-07 27.1 In-house 177-287 (307) alignment
Range on Protein: 274-351
Range on HMM: 177-287/307.0
ETEQRCMMLT-------------------EDTKLNDMFDGFLDLVQRARR------AKRNVLVCSTRGRNRAPAFASAYLMSKEQ--------IPRQAAV
.   |.. .|                    |... . |. .||.....|.       .  ||| .. | .|...|. |||| .          .. . ||
gytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfeelldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleav

AKVRTAMGTMR
...|   . . 
kllreqRpgav

0043147 (Phosphotyrosine protein) phosphatases II 288-351 1.3e-07 27.0 In-house 80-144 (172) alignment
Range on Protein: 288-351
Range on HMM: 80-144/172.0
LNDMFDGFLDLVQR--ARRAKRNVLVCSTRGRNRAPAFASAYLMSkEQIPRQAAVAKVRTAMGTMR
| .... ||.....  |.. .  |||  . | .|..... ||||  .... . ||| ||.. . . 
llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml.lglsleeavalvrekRpgav

0039614 (Phosphotyrosine protein) phosphatases II 284-352 2.6e-07 25.9 In-house 194-273 (297) alignment
Range on Protein: 284-352
Range on HMM: 194-273/297.0
EDTKLNDMFDGFLDLVQRARR------AKRNVLVCSTRGRNRAPAFASAYLM-----SKEQIPRQAAVAKVRTAMGTMRP
 | .  . .. .|.... .|.       .. ||| .. | .|. .|. ||||     .. ..  . ||...| . . ...
pdhgvppslellleflelvrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavq

0040438 (Phosphotyrosine protein) phosphatases II 281-366 2.7e-07 25.7 In-house 162-274 (317) alignment
Range on Protein: 281-366
Range on HMM: 162-274/317.0
MLT------------------EDTKLNDMFDGFLDLVQRARRA----KRNVLVCSTRGRNRAPAFASAYLM-----SKEQIPRQAAVAKVRTAMGTMRPP
...                   | .. . .| .||.....|.|    .  ||| .. | .|. .|. ||||      ....  . ||...| . . . . 
evedlgdsesrtvthfhytgWpdhgvppspdllldfleavrealedpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqt

VNISDFMQRKLMR
 .   |. . |. 
peqyrflydalle

0040439 (Phosphotyrosine protein) phosphatases II 285-352 2.7e-07 25.9 In-house 152-230 (249) alignment
Range on Protein: 285-352
Range on HMM: 152-230/249.0
DTKLNDMFDGFLDLVQRARR------AKRNVLVCSTRGRNRAPAFASAYLM-----SKEQIPRQAAVAKVRTAMGTMRP
|... . |. .||.....|        .  ||| .. | .|...|. ||||      . ... . ||...|.. . . .
dhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdleeavkllrsqRpgavq

subfamily_DSP8_pd Subfamily DSP8 285-371 2.8e-07 24.3 In-house 72-154 (159) alignment
Range on Protein: 285-371
Range on HMM: 72-154/159.0
DTKLNDMFDGFLDLVQRARRAKRNVLVCSTRGRNRAPAFASAYLMSKEQIPRQAAVAKVRTAMGTMRPPVNisdFMQrKLMRYQQHL
| || ..||  .. ...|.... .|||    |. |... | ||.| . ..  . |   |.    |. | .|   |.. .|. |...|
dekllpwfdksvefidkaksengrvlvhvlaGisrsatvaiayimktlemsldeayrfvkekrptispnln...flg.qLleyekel

subfamily_DSP12_pd Subfamily DSP12 284-355 4.1e-07 24.5 In-house 60-131 (155) alignment
Range on Protein: 284-355
Range on HMM: 60-131/155.0
EDTKLNDMFDGFLDLVQRARRAKRNVLVCSTRGRNRAPAFASAYLMSKEQIPRQAAVAKVRTAMGTMRPPVN
... . . .|  .| .. |.  ...|||  . |  |  ..  |||| ||... . |. .|...  ...|  .
peediLshldeavdFieealeeegavlvHCqagvSRSvtiviAYlmkkeklslekAlklvkekkpeiepNeg

subfamily_DSP14_pd Subfamily DSP14 284-371 5.2e-07 23.7 In-house 61-144 (157) alignment
Range on Protein: 284-371
Range on HMM: 61-144/157.0
EDTKLNDMFDGFLDLVQRARRAKRNVLVCSTRGRNRAPAFASAYLMSKEQIPRQAAVAKVRTAMGTMRPpvNISdFMqRKLMRYQQHL
...|| . ||   | .. ..... ..||  . |. |  ... ||||  |..  . |   |..|   .||  |.  |  ..|..| ..|
peaklakhfdevadkieevkkkggktlvhCvaGvSRSAslclaylmkyeklsLreayklvksaRpiirP..NvG.Fw.kqlidyEkkl

subfamily_STYXL1_pd Subfamily STYXL1 290-355 5.6e-07 22.9 In-house 76-141 (157) alignment
Range on Protein: 290-355
Range on HMM: 76-141/157.0
DMFDGFLDLVQRARRAKRNVLVCSTRGRNRAPAFASAYLMSKEQIPRQAAVAKVRTAMGTMRPPVN
. ..   ..... .. .. ||| |..|  |. | . |||| ...|  . | ....     ..|  .
erlkeavqfiekhkkegevvlvfsnkGisrsaaviiaylmyskkitlkkaykylkkCkenvkPnra

subfamily_DSP10_pd Subfamily DSP10 283-371 7.4e-07 23.2 In-house 69-153 (159) alignment
Range on Protein: 283-371
Range on HMM: 69-153/159.0
TEDTKLNDMFDGFLDLVQRARRAKRNVLVCSTRGRNRAPAFASAYLMSKEQIPRQAAVAKVRTAMGTMRPPVNisdFMQrKLMRYQQHL
|.  .|.  |.  |. .. ||.  ..|||    |  |. ... |||| . ..  . |   |...  .. | .|   ||  .|... ..|
tskqnlkqyfeealefieearkkgsrvLvhCqaGisrsatvviaYlmkhlnlslndaykfvkekrpiisPnLn...fmG.qLlefekel

0049260 (Phosphotyrosine protein) phosphatases II 288-352 9.9e-07 24.1 In-house 70-134 (152) alignment
Range on Protein: 288-352
Range on HMM: 70-134/152.0
LNDMFDGFLDLVQR-ARRAKRNVLVCSTRGRNRAPAFASAYLMSkEQIPRQAAVAKVRTAMGTMRP
| .... .|..... |.. . .|||  . | .|..... ||||   ... . ||| ||..   . |
lsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml.lgvsleeavalvrekRpgavp

0036282 (Phosphotyrosine protein) phosphatases II 288-347 1.1e-06 24.0 In-house 85-146 (174) alignment
Range on Protein: 288-347
Range on HMM: 85-146/174.0
LNDmFDGFLDLVQRARRA--KRNVLVCSTRGRNRAPAFASAYLMSKEQI-PRQAAVAKVRTAM
|.  .. |...|..|.    .. |||  . |..|..... |||| . .. . . |.. ||.. 
lsi.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrglleslvdaldlvrelR

subfamily_Choan-DSP_MKP-1_pd Subfamily Choan-DSP_MKP-1 284-351 1.7e-06 21.6 In-house 64-131 (148) alignment
Range on Protein: 284-351
Range on HMM: 64-131/148.0
EDTKLNDMFDGFLDLVQRARRAKRNVLVCSTRGRNRAPAFASAYLMSKEQIPRQAAVAKVRTAMGTMR
..  |. .|. . . |..|. . | |||  . |. |. | | ..|.  ...  . |.| |. .   ..
pkedlsaiFediiafvrkakdeGrrvLvhlqmGvsrssalallwlidfkrvslkealalvkskrryvd

0037934 (Phosphotyrosine protein) phosphatases II 285-352 1.9e-06 23.1 In-house 152-226 (243) alignment
Range on Protein: 285-352
Range on HMM: 152-226/243.0
DTKLNDMFDGFLDLVQR-----ARRAKRNVLVCSTRGRNRAPAFASAYLMSKE-QIPRQAAVAKVRTAMGT-MRP
 . | |..|   . ...     |.  .. |||  . |..|. ... |||| .  ... . ||...|.  .  . .
pedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtliaaylmllllgvdleeavkllreqRpgkavq

0051082 (Phosphotyrosine protein) phosphatases II 252-346 2.3e-06 22.8 In-house 48-131 (151) alignment
Range on Protein: 252-346
Range on HMM: 48-131/151.0
ECPCFCNRSSSHFRYYLSYSLPETEqrcmmltedtkLNDMFDGFLDLVQRARRA-KRNVLVCSTRGRNRAPAFASAYLMSkEQIPRQAAVAKVRTA
 ||..... . .....   . |..            | ..|| .|.... ...  . .|||  . |..|  ... .|||  .... ..|.. .|  
ycpeylpelgievlhipildwpdpg...........lplsfdavleflellldkkngpvlvHCsaGkgRTGtlvalylml.lgvsleealeeyrlk

0051429 (Phosphotyrosine protein) phosphatases II 275-363 3.1e-06 22.6 In-house 117-220 (272) alignment
Range on Protein: 275-363
Range on HMM: 117-220/272.0
TEQRCMMLTEDTKLNDMF---DGFLDLVQRARRaKRNVLVCSTRGRNRAPAFASAYLMSkEQIP--------------RQAAVAKVRTAMGTMRPPVNIS
.| | .|.   |   |.    . .|.|..  .. ...|||  . |..|   .. ..|.  ....               ..||...| ..  ...     
gearevmhlhytdwpdhgvpqeallellellld.ggpvlvHCsaGkdRTGtvvalllll.lgvsletivddYlltnlyleeaveelraqrpgavqteeqy

DFMQRK
 | .. 
lflyea

0045098 (Phosphotyrosine protein) phosphatases II 288-360 3.4e-06 22.1 In-house 172-264 (278) alignment
Range on Protein: 288-360
Range on HMM: 172-264/278.0
LN--DMFDGFLDLVQRARR--------------AKRNVLVCSTRGRNRAPAFASAYLMSKE---QIPRQAAVAKVRTAMGT-MRPPVNISDFM
|.  . |. .|. ...|..               .  |||    | .|. ... |||| .    ..  . ||...|.  .  . .  .   |.
lpilksflellefirealkllaslllsslllldsggpvlVHCsaGvgRtGtlvaaylmlelleggvdlleavkelrsqRpglavqnleqyrfl

subfamily_DSP1_pd Subfamily DSP1 285-374 3.9e-06 21.1 In-house 74-159 (163) alignment
Range on Protein: 285-374
Range on HMM: 74-159/163.0
DTKLNDMFDGFLDLVQRARRAKRNVLVCSTRGRNRAPAFASAYLMSKEQIPRQAAVAKVRTAMGTMRPPVNisdFMqRKLMRYQQHLGID
.  .  .|.  .. ........  ||.    |  |. ..  ||||.....  . |   |.     ..| ..   |. ..|..|...|. .
kadislvfeeviefidevkkknGkvlihCqaGisRsstlclaylmktkrvsleeafdfvkqrRsiisPnag...Fv.lqLlnyekkllle

subfamily_DSP15_pd Subfamily DSP15 273-369 4e-06 21.0 In-house 43-137 (151) alignment
Range on Protein: 273-369
Range on HMM: 43-137/151.0
PETEQRCMML--TEDTKLNDMFDGFLDLVQRARRAKRNVLVCSTRGRNRAPAFASAYLMSKEQIPRQAAVAKVRTAMGTMRPPVNisdfMQRKLMRYQQ
...| .|...  | ..||. .|.   ... ..|  . ||||    |  |.   . ||||.  ..  . |.  ...|  .  | .      .|.|. |..
kdieYkciaasDtpsaklskffkesvefihkcRlkeenvlvhClaGvsRsvtlvvaYlmtvtelnwrdalevikaaRsvanPnfG....fkrqlkeyek

0036941 (Phosphotyrosine protein) phosphatases II 283-346 8.2e-06 20.8 In-house 178-255 (297) alignment
Range on Protein: 283-346
Range on HMM: 178-255/297.0
TEDTKLNDMFDGFLDLVQRARR------AKRNVLVCSTRGRNRAPAFASAYLM--------SKEQIPRQAAVAKVRTA
  | .. . .. .||.....|.       .  ||| .  | .|. .|. |.||          ....   || |.|. 
wpdhgvpespaslldfielvrkvlkllpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReq

subfamily_DSP6_pd Subfamily DSP6 286-373 8.9e-06 19.3 In-house 73-156 (158) alignment
Range on Protein: 286-373
Range on HMM: 73-156/158.0
TKLNDMFDGFLDLVQRARRAKRNVLVCSTRGRNRAPAFASAYLMSKEQIPRQAAVAKVRTAMGTMRPPVNisdFMQrKLMRYQQHLGI
..|  .|   ..... ||..| .|||    |  |. . . ||||.|...  . | . |..    . |  |   ||. .|. ....|..
qnlakffPeaiefidearskkskvlvhClaGisrsvtvtlaylmkklalslndaydlvkkrksnisPnfn...fmg.qlldferslrl