subfamily_Cele-PTP-19_pd |
Subfamily Cele-PTP-19 |
1008-1306 |
1.1e-179 |
590.6 |
In-house |
2-300 (301) |
alignment |
Range on Protein: 1008-1306
Range on HMM: 2-300/301.0
KVKKVELWTMSLPNKDDHKPAKFYNTTIENVNVTTIDKDHITESYAYLPEDKHRYPTVPCKPSTAVEVIVDGKRAPIHANWVPTPGHPHRFIATQSPINA
||||.|.|..| ..|||.|.|||||||||||||||||||||||||||||.||||||||||||||||||||||||.||||||.||.||||||||||.|...
kvkkiekwiiskdfkdddktakfynttienvnvttidkdhitesyaylpkdkhryptvPckPstavevivdGkrvPihanwiptsGhphrfiatqgPlkn
TCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDLQVGRFMIKMTNMDFIVQKNIMRRSFKVADSTGKFAARTLTHYQYSQWAERGVPKSHV
|.||||||..||.||.|||.|.|||........|||......|..|||.||..|...|..|.|..|...|.|||||||.||.||||||.|..|||||||.
tsedfwamlvqydvekivmlgqkvekleekceeylpvkisekldigrfkikiknkelilnkkiskrtlevedstgkfatrtvthyqysewtdrgvPksha
ETYELMEMVKKSEKPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQLYWMTLGTMYRLIKEYGFDMKIYDQQMAMFN
|...|||.|||||||||||||.|||||.||||||||||.||||||||||||||||.||||||||||||||||||||.||||||||||||||..|.|||.
elfdlmelvkksekPivvhcsaGiGrsvafigteylareveadptieltealkhlrehrwngvqtnsqlywmtlGtvyrlikeygfdmkiyeeqlamfd
|
0036941 |
(Phosphotyrosine protein) phosphatases II |
1058-1306 |
3.7e-62 |
205.6 |
In-house |
41-295 (297) |
alignment |
Range on Protein: 1058-1306
Range on HMM: 41-295/297.0
DKHRYPTVPCKPSTAVEViVDGKRAPIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDLQVGRFMI
.|.||. ... ..| | . |.. |.|..|........||||| | . |.|||| |.... |..|||. . ||.... | |.. .. |..|.|..
eknRykdilpydhtRVkl.ddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqnvtvIvmltelvelgrekcaqywpleegesltygdftv
KMTNMDFIVQKNIMRRSFKVADStGKFAARTLTHYQYSQWAERGVPKSHVETYELMEMVKK------SEKPIVVHCSNGIGRSMAFIGTEYLARQVE---
...... . ... .| ..| | |. ||.||..| | . ||| |. . ...|.|.| |..|..||||.|.|||..||. ... .|.|
tllsvevvllddytlrtlevtdt.gngesrtvthfhytgwpdhgvpespaslldfielvrkvlkllpsggpvlVHCsaGvgRsgtfiaadlmlqqledkl
ADPTIELTEALKHLHEHRWNGVQTNSQLYWMtLGTMYRLIKEYGFDMKIYDQQMAMFN
... . ||.|.| |.|.. ||| .|.... ... |.| . ... .... .....
keggvdileavkklReqRpgavqtleqyrfl.yeallellkkkltkepllklvlllls
|
0040438 |
(Phosphotyrosine protein) phosphatases II |
1032-1292 |
1.6e-60 |
200.4 |
In-house |
19-276 (317) |
alignment |
Range on Protein: 1032-1292
Range on HMM: 19-276/317.0
NTTIENVNVTTIDKDHITESYAYLPEDKHRYPTVPCKPSTAVEVIVDGK---RAPIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVG
| .. ....|...... . ||.||| ... ... | . ..|. |.|..|..| ....|||||.| . |.|||| |.... |..|||.
alleefedllslkldtysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPlpntvedFwrmvweqgvtvivmLt
RKVEYWKNIHNDYLPMwpRNDLQVGRFMIKMTNMDFivQKNIMRRSFKVADStGKFAARTLTHYQYSQWAERGVPKSHVETYELMEMVKKS----EKPIV
. .|.... | |. .. |..|.|........ ..| | ..| |. |. ||.||..| | . |||.|. . ...|.|... ..|..
eleelgrekcaqYwpl..getltygdftvtllseee..lagitlrtlevedl.gdsesrtvthfhytgWpdhgvppspdllldfleavrealedpggpvl
VHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQLYWMtlgtmYRLIKEYG
||||.|.||...||. ... .|.| .. ..||.|.| |.|...||| .|.... |... ||
VHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrfl.....ydalleyl
|
0045450 |
(Phosphotyrosine protein) phosphatases II |
1005-1278 |
4.8e-59 |
195.9 |
In-house |
7-295 (307) |
alignment |
Range on Protein: 1005-1278
Range on HMM: 7-295/307.0
KLLKVKKVELWTMSLPNKDDHKPAKFYNttiENVNVTTIDKDHITESYAYLPEDKHRYPTVPCKPSTAVEVIVDGK----RAPIHANWV--------PTP
......| .|. . |. .. .. .| .. . ..||... ....... . ||.||. ... ..| | . . .. |.|..| ...
lfidalkllllvllllldfltgllkefe...kllsvtvfllgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgy
GHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWpRNDLQVGRFMIKMTNMDFivQKNIMRRSFKVADSTGKFAARTLTHY
....|||||.| . |.|||| |. .. |..|||. . ||..... | | . |. |.| ....... .... .| ..| |. |.. ||.||.
dlkrkfIatqgPlpetvedFwrmlweqgvtvivmltelvelgrekcaqywPde.geeltygnftvtllseeh..ldgytvrtlevtdldgtgesrtvthf
QYSQWAERGVPKSHVETYELMEMVKK------SEKPIVVHCSNGIGRSMAFIGTEYLARQVEADPT---IELTEALKHLHEHRWNGVQTNSQLYW
.| | . |||.| |. ...|.|.| ...|..|||| |.||...||. .. ||.|...| . | ||.|.| |.|...||. .|...
hytgwpdhgvppsfeelldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrf
|
0050432 |
(Phosphotyrosine protein) phosphatases II |
1045-1279 |
2.2e-56 |
186.8 |
In-house |
57-291 (308) |
alignment |
Range on Protein: 1045-1279
Range on HMM: 57-291/308.0
KDHITESYAYLPEDKHRYPTVPCKPSTAVEVivDGKRAPIHANWVPTP--GHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYL
.. .. ||.||. ... .. | . |.. |.|..|... ..|..|||||.| . |.|||| |.....|..|||. . ||. .. |
lleysvallpenkdkNrykdilpydhsRVkl..degsdYInAsyvdgyssklprkfIatqgPlpntvedFwrmvweqnvrvIvmLtklvengrekcaqYw
PMWPR-NDLQVGRFMIKMTNMDFivQKNIMRRSFKVADSTGKfAARTLTHYQYSQWAERGVPKSHVETYELMEMVKKS--EKPIVVHCSNGIGRSMAFIG
|. . . |..|.| ....... ......| ... .. .. ||.||..| | . ||| | . ...|.|.|| ..|||||||.|.||...||
plelgggsleygkftvtllseev..lddytvrtleltnlgdg.esrtvthfhytnWpdhgvPpspeilldflelvrkslpggpivVHCsaGvGRtGtfia
TEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQLYWM
..| .|.|.. .. . ||.|.| |.|.. ||| .|....
ldllleqlekeggvdvfeavkklReqRpgmvqtpeqylfl
|
0047943 |
(Phosphotyrosine protein) phosphatases II |
1055-1279 |
8.4e-54 |
178.2 |
In-house |
37-264 (273) |
alignment |
Range on Protein: 1055-1279
Range on HMM: 37-264/273.0
LPEDKHRYPTVPCKPSTAVEViVDGKRAPIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRN-DLQVG
||.||. ... .. | . ||. |.|..|... ....||||| | . |.|||| |.... |..|||. . || ... . | |.. . |..|
enkdknrykdilpydhsrvkl.gdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvweqnvrviVmLtelvelgrekcaqYwpleggelsltyg
RFMIKMTNMDFivQKNIMRRSFKVADSTGKFaARTLTHYQYSQWAERGVPKSHVETYELMEMVKK------SEKPIVVHCSNGIGRSMAFIGTEYLARQV
.| ....... .... | ... .. . || ||..| | . ||| | . |..|.|.| |..|.|||||.|.||...|| ..| .|.
kftvtllseet..kddytvrtleltnlgtge.srtvthfhytgwpdhgvppslesllefielvrkalealpsngpvvVHCsaGvgRtgtfialdllldql
EADPTIELTEALKHLHEHRWNGVQTNSQLYWM
|. .. . ||.|.| ..|...||| .|....
ekeggvdvleavkllrsqRpgmvqtpeqyrfl
|
0039614 |
(Phosphotyrosine protein) phosphatases II |
1041-1279 |
1.6e-53 |
177.5 |
In-house |
42-281 (297) |
alignment |
Range on Protein: 1041-1279
Range on HMM: 42-281/297.0
TTIDKDhITESYAYLPEDKHRYPTVPCKPSTAVEVIVDGK----RAPIHANWVPTPGH-PHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWK
. | ..... . ||.||. ... ... | . . .. |.|..|... . ...||||| | . |.|||| |. .. |..|||. . ||...
lslkpd.ysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIatqgPlpetvedFwrmvweqgvtvivmLtklvelgr
nIHNDYLPMWPRndlQVGRFMIKMTNMDFivQKNIMRRSFKVADsTGKFaaRTLTHYQYSQWAERGVPKSHVETYELMEMVKK------SEKPIVVHCSN
.| | . |.| ..... . .....| ..| . .|. ||.||.|| | . ||| |. .|..|.|.. ...|..||||.
.kcaqywpeegg...tygdftvtllkveh..ldgytvrtlevtn.nges..rtvthfqytgwpdhgvppslellleflelvrealaelpkggpvlVHCsa
GIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQLYWM
|.||. .||. .. .|.| .. . ||.|.| |.|...||| ||...
GvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrfl
|
0046845 |
(Phosphotyrosine protein) phosphatases II |
1048-1279 |
1.6e-53 |
177.3 |
In-house |
20-266 (284) |
alignment |
Range on Protein: 1048-1279
Range on HMM: 20-266/284.0
ITESYAYLPEDKHRYPTVPCKPSTAVEVIVDGK----RAPIHANWVPTP-----GHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIH
.. .... .|.||. ... .. | . . .. |.|..|... ....||||| | . |.|||| |.....|..|||. . ||. .. .
lsvallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqnvrvIVmltelvengrekc
NDYLPMWpRNDLQVGRFMIKMTNMDFivQKNIMRRSFKVADSTGKFAARTLTHYQYSQWAERGVPKSHVETYELMEMVKKS------EKPIVVHCSNGIG
| |.. . |. |.|........ ......| ... . . ||.||..| .| ..||| | |....|... ..|||||||.|.|
aqYwple.gevltygdftvtllseev..kddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrellenlpgggpivVHCsaGvg
RSMAFIGTEYLARQVEADP---TIELTEALKHLHEHRWNGVQTNSQLYWM
|...|| ..| .|.|.. .. . ||.|.| |.|.. ||| .|...
RtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfv
|
0043336 |
(Phosphotyrosine protein) phosphatases II |
1034-1278 |
7.8e-53 |
175.1 |
In-house |
23-268 (278) |
alignment |
Range on Protein: 1034-1278
Range on HMM: 23-268/278.0
TIENVNVTTIDKDHITESYAYLPEDKHRYPTVPCKPSTAVEVIVDGKR---APIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRK
| .......|... .. . ||.||. ... ... | . ..|.. |.|..|... .|..||||| | . |.|||| |. .. |..|||. .
llefeellsfkldtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpetvedFwrmvwelgvttivmLtel
VEYWKNIHNDYLPmwpRNDLQVGRFMIKMTNMDFivQKNIMRRSFKVADSTGKFAaRTLTHYQYSQWAERGVPKSHVETYELMEMVKK----SEKPIVVH
||.... | | .. |..|.| ....... ......| ..| . .. || |||.| | . ||| | .....|.. |..|..||
velgrvkcaqYwp...ggsltygdftvtllkeeh..lddytvrtlevtnlgdges.rtvthyhylgwpdhgvpeslsllldflkavrealedsngpvlVH
CSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQLYW
||.|.||...||. ..| .|.| .. | ||.|.| |.|.. ||| ||...
CsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrf
|
0051299 |
(Phosphotyrosine protein) phosphatases II |
1048-1279 |
1.6e-52 |
174.1 |
In-house |
41-278 (288) |
alignment |
Range on Protein: 1048-1279
Range on HMM: 41-278/288.0
ITESYAYLPEDKHRYPTVPCKPSTAVEVIVDGK---RAPIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPM
.. .. .|.||. ... .. | . | .. |.|...... ....||||| | . |.|||| |.....|..|||. . ||. .. | |.
lsaallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyidgynlkrkfIatqgPlpntvedFWrmvweqnvrvIvmltklvelgrekcaqYwpl
wpRNDLQVGRFMIKMTNMDFivQKNIMRRSFKVADST---GKFAARTLTHYQYSQWAERGVPKSHVETYELMEMVKKS----EKPIVVHCSNGIGRSMAF
.. |..|.......... ..... | ..| . . |. || ||..| .| . ||| | . .....|.|. ..|.|||||.|.||...|
..ggsltygditvtllseev..lddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdspellldflrlvrkalasgggpvvVHCsaGvgRtgtf
IGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQLYWM
| ..| .|.|. .... ||.|.| |.|.. ||| .|...
ialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfv
|
Y_phosphatase |
Protein-tyrosine phosphatase |
1058-1279 |
1.7e-51 |
170.3 |
Pfam-A |
3-229 (235) |
alignment |
Range on Protein: 1058-1279
Range on HMM: 3-229/235.0
DKHRYPTVPCKPSTAVEV-IVDGKRAPIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDLQVGRFM
.|.||..... .| |.. .|. |.||.| . ....||||| |.. |.||||.|..|..|. |||. . .| .. ..| | .. |. |..
kknRykdilpydktrvklkgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesltygdik
IKMTNMDFIVQKNIMRRSFKVADSTGKFAARTLTHYQYSQWAERGVPKSHVETYELMEMVKKSE----KPIVVHCSNGIGRSMAFIGTEYLARQVEADPT
..... .|... | ... ..... . |......| .| ..|||.| . .|...|.||. .|.|||||.|.||.. |. ..| .|.||. .
velkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleqleaeee
IELTEALKHLHEHRWNGVQTNSQLYWM
... ...|.| ..| . ||. .|....
vdvlqivkelRkqRpgmvqsleqYifl
|
Y_phosphatase |
Protein-tyrosine phosphatase |
1058-1279 |
1.7e-51 |
170.3 |
In-house |
3-229 (235) |
alignment |
Range on Protein: 1058-1279
Range on HMM: 3-229/235.0
DKHRYPTVPCKPSTAVEV-IVDGKRAPIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDLQVGRFM
.|.||..... .| |.. .|. |.||.| . ....||||| |.. |.||||.|..|..|. |||. . .| .. ..| | .. |. |..
kknRykdilpydktrvklkgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesltygdik
IKMTNMDFIVQKNIMRRSFKVADSTGKFAARTLTHYQYSQWAERGVPKSHVETYELMEMVKKSE----KPIVVHCSNGIGRSMAFIGTEYLARQVEADPT
..... .|... | ... ..... . |......| .| ..|||.| . .|...|.||. .|.|||||.|.||.. |. ..| .|.||. .
velkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleqleaeee
IELTEALKHLHEHRWNGVQTNSQLYWM
... ...|.| ..| . ||. .|....
vdvlqivkelRkqRpgmvqsleqYifl
|
0040439 |
(Phosphotyrosine protein) phosphatases II |
1049-1278 |
2.7e-51 |
170.0 |
In-house |
4-237 (249) |
alignment |
Range on Protein: 1049-1278
Range on HMM: 4-237/249.0
TESYAYLPEDKHRYPTVPCKPSTAVEVIVDGKRAP---IHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMw
.... . ||.||| ... ... | . . ... . |.|...... ...|||||| | . |.|||| |. .. ...|||. . ||.... | |.
svallpenkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywpl.
pRNDLQVGRFMIKMTNMDFivQKNIMRRSFKVADStGKFAARTLTHYQYSQWAERGVPKSHVETYELMEMVKK------SEKPIVVHCSNGIGRSMAFIG
.. |..|.|........ .....| ... .. .. || .|.|| | . |||.| .. ...|.|.| ...|..||||.|.||. .||.
.ggsleygdftvtllsvev..kddytvrtleltnl.ydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfia
TEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQLYW
.. .|.| .. | ||.|.| ..|...||. .|...
aylmleqlekelgvdleeavkllrsqRpgavqnpeqyrf
|
DSPc_SM00195 |
|
1045-1279 |
9.1e-51 |
168.1 |
In-house |
16-254 (263) |
alignment |
Range on Protein: 1045-1279
Range on HMM: 16-254/263.0
KdHITESYAYLPEDKHRYPTVPCKPSTAVEVIVDG---KRAPIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDY
| ..||. ..|.|| ... .| |.. . . |.||.. .. .....|||| | . |.|||| |... .|. |||. . .| |. ..|
k.etteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengkekcdry
LPMWPRNDLQVGRFMIKMTNMDFIVqKNIMRRSFKVADSTGkFAARTLTHYQYSQWAERGVPKSHVETYELMEMVKKSEK----PIVVHCSNGIGRSMAF
| . ..|.. .|... . ..| .| ... . .|..|.||| .| ..|||.|. .. ||...||||.. |||||||.|.||. .|
wpeesggketfgkisvklvevekkk.deiilrtleltkegk.eetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivVhCsaGvgRtgtf
IGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQLYWM
. .... ...|.. .... | .|.| ..| . ||| |. ..
vtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfi
|
PTPc_SM00194 |
|
1045-1279 |
9.1e-51 |
168.1 |
In-house |
16-254 (263) |
alignment |
Range on Protein: 1045-1279
Range on HMM: 16-254/263.0
KdHITESYAYLPEDKHRYPTVPCKPSTAVEVIVDG---KRAPIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDY
| ..||. ..|.|| ... .| |.. . . |.||.. .. .....|||| | . |.|||| |... .|. |||. . .| |. ..|
k.etteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengkekcdry
LPMWPRNDLQVGRFMIKMTNMDFIVqKNIMRRSFKVADSTGkFAARTLTHYQYSQWAERGVPKSHVETYELMEMVKKSEK----PIVVHCSNGIGRSMAF
| . ..|.. .|... . ..| .| ... . .|..|.||| .| ..|||.|. .. ||...||||.. |||||||.|.||. .|
wpeesggketfgkisvklvevekkk.deiilrtleltkegk.eetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivVhCsaGvgRtgtf
IGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQLYWM
. .... ...|.. .... | .|.| ..| . ||| |. ..
vtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfi
|
0042113 |
(Phosphotyrosine protein) phosphatases II |
1056-1279 |
9.5e-50 |
164.6 |
In-house |
9-235 (245) |
alignment |
Range on Protein: 1056-1279
Range on HMM: 9-235/245.0
PEDKHRYPTVPCKPSTAVEVIVDGKRA---PIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMwpRNDLQV
||.||. ... ..| | . .|| . .|.|..|... ....||||| | . |.|||| |. .. ...|||. . .|.... | |. .. |..
nkdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywpl..geslty
GRFMIKMTNMDFivQKNIMRRSFKVADsTGKFAARTLTHYQYSQWAERGVPKSHVETYELMEMVKK-----SEKPIVVHCSNGIGRSMAFIGTEYLARQV
|.|........ .....| ..| . .|.. |. .||.| | . ||| .. ...|.|.| |..|..|||| |.||...||. ....|.
gdftvtllseeh..lddytvrtlevtn.lgddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleql
EADPTIELTEALKHLHEHRWNGVQTNSQLYWM
|. .. | ||.|.| ..|.. ||| ||....
ekelgvsleeavkelrsqRpgavqtpsqyrfl
|
0045098 |
(Phosphotyrosine protein) phosphatases II |
1046-1279 |
5.8e-48 |
159.0 |
In-house |
23-264 (278) |
alignment |
Range on Protein: 1046-1279
Range on HMM: 23-264/278.0
DHITESYAYLPEDKHRYPTVPCKPSTAVEvivdgkrAPIHANWVPTPghPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPmw
. ||.. . ||.||. ... ... | |.|...... |..||||| | . |..||| |. .. ...|||. . ||. .. | |
seitpalylgnldknRykdilpydhsrVk.......dYINAsyidgy..pkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaqywp..
PRNDLQVGRFMIKMTNMDFIvqKNIMRRSFKVADS---TGKFAARTLTHYQYSQWAERGVPKSH--VETYELMEMVKK-----------------SEKPI
... |. |.| ....... . ... | ..| . . |..||..| | . ||| .. ||.|.... |..|.
eggsltygdftvtllseevl..ddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpv
VVHCSNGIGRSMAFIGTEYLARQVeaDPTIELTEALKHLHEHRWN-GVQTNSQLYWM
.|||| |.||. .... .. ... .... | ||.|.| ..|.. ||. .|....
lVHCsaGvgRtGtlvaaylmlell..eggvdlleavkelrsqRpglavqnleqyrfl
|
0037934 |
(Phosphotyrosine protein) phosphatases II |
1054-1278 |
1.1e-42 |
141.7 |
In-house |
8-233 (243) |
alignment |
Range on Protein: 1054-1278
Range on HMM: 8-233/243.0
YLPEDKHRYPTVPCKPSTAVEVivDGkRAPIHANWVPTPGhphRFIATQSPINATCED----FWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPmwprND
. .|.||..... . . | . .| |.||... .. |.|||| | . |.|| || |. .. ...|||. . ||.... | | ..
penlsknrysdilpydhsrvkl..eg.sdyinanliyvtp...rliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywp....ge
LQVGRFMIKMTNMDFivQKNIMRRSFKVADSTGKFAARTLTHYQYSQWAERGVPKSHVETYELMEMVK------------KSEKPIVVHCSNGIGRSMAF
. |.|....... .... | ... . |. .||.| | . ||| |. ......|. .|..|..|||| |.||. ..
vtygdftvtllseeh..lddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtl
IGTEYLARQVeadpTIELTEALKHLHEHRWN-GVQTNSQLYW
| .. ... .. | ||.|.| |.|.. .||| ||...
iaaylmllll....gvdleeavkllreqRpgkavqtpsqyrf
|
subfamily_PTPRD_pd |
Subfamily PTPRD |
1084-1291 |
4.2e-39 |
129.6 |
In-house |
79-280 (564) |
alignment |
Range on Protein: 1084-1291
Range on HMM: 79-280/564.0
IHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWpRnDLQVGRFMIKMTNMDfiVQKNIMRRSFKVaDSTGK
| |... . ... .|||| |.. |.|||| |....... |||. . .| |. ..| | . ..|........ .... |.||. . .
INAsfidgyrkrkayIAtqgPlaetiedFWRmvweqnsstiVmltkleEkgkvkchkYWPek.g.tetygeltVtleeee..eladyeirtfkl.kkkks
FAARTLTHYQYSQWAERGVPKSHVETYELMEMVKKS----EKPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQlYWM
.|. ..... .| ..|||.| . .|.. |... ..|||||||.|.||. .|| ... ...... |... . .|.| ..| |||..| |
sesreVrqFhFtsWPdhgvpesatslLdlirkvralnepdagPivVhCSaGVGRTGtfividamlerikeektvDiyqyvkalrkqRnamVqteeQ.YiF
tlgtMYRLIKEY
... | |.
....iheailea
|
subfamily_Cele-PTP-18_pd |
Subfamily Cele-PTP-18 |
1058-1280 |
7.2e-39 |
128.3 |
In-house |
50-280 (305) |
alignment |
Range on Protein: 1058-1280
Range on HMM: 50-280/305.0
DKHRYPTVPCKPSTAVEVIVDGKRAPIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDLQVG----
.| || | | | . ||||.| || |.||| ||.|.. || ||| ||.| || | |. .| . .|.. .. |.
gknrykdvgcldnnrvklegpwpheyihanyvstptnpkrfictqaplektcadfwymclqdkveaifmlcnllekgakkcleyfaskdkdvlefeekgq
RFMIKMT---NMDFIVQKN-IMRRSFKVADSTGKfAARTLTHYQYSQWAERGVPKSHVETYELMEMVKKSEKPIVVHCSNGIGRSMAFIGTEYLARQVEA
. ..|. ...| . . .... | . .|. || ||| . .| .|||| . . ||.| . | ||||||| ||||. . . ||. |. |
kisvkfessvtlkfrkdakakvtetvlviegpge.karkvthyhwidwpdrgvpaadlailellekarpskgpivvhcsagigrtgsvvmleyildqlla
DPTIELTEA-LKHLHEHRWNGVQTNSQLYWMT
|| |. |... | | | .||. | ..
gqiiedtdkilqkireqrnnsiqtdaqylfvh
|
subfamily_Choan-PTP-1_pd |
Subfamily Choan-PTP-1 |
1053-1279 |
5.6e-36 |
119.1 |
In-house |
38-268 (281) |
alignment |
Range on Protein: 1053-1279
Range on HMM: 38-268/281.0
AYLPEDKHRYPTVPCKPSTAVEVIVDG---KRAPIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPmWPRND
| |.|| . | |.| . . | ||.||. ....||||.|. |....|| | ....|. |||| |..| | | | ....
adenvlknrYsnivaYDatrvkvtpneenkntDYinanfvpgykgekeyiatqgPvPaslvafWqmvweqkvsaivmvtreieagklkChrYWP.ddnse
LQVGRFMIKMTNMDfiVQKNIMRRSFKVADSTGKfaARTLTHYQYSQWAERGVPKSHVETYELMEMV-----KKSEKPIVVHCSNGIGRSMAFIGTEYLA
|..| ...|.|. ... ..| ||. ..|. .|.... .| .| . |||.. | | . | ||.. |.|.||| |.||. ..|. . |.
lkygdvtvkstaee..ekatyierkfkleresge..treveqlaytaWPdhGvPattkellefrkevlkltekktkaplvihCsaGvGrtGtyialDrlv
RQVEAD-PTIELTEALKHLHEHRWNGVQTNSQLYWM
..|||. ....... ...| ..| ||| | ..
kaveaeleeldvkavvaelrkernlmvqtvvqyefv
|
subfamily_Anemone-PTP-5_pd |
Subfamily Anemone-PTP-5 |
1040-1303 |
7.9e-36 |
118.7 |
In-house |
32-298 (319) |
alignment |
Range on Protein: 1040-1303
Range on HMM: 32-298/319.0
VTTIDKDHITESYAYLPEDKHRYP-TVPCKPSTAVEVIVDGKRA--PIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKN
. . ..|..... ..| ||. ... . | .||. | |... . . ..|||||.|.. | |||| | ..|. .||. . || |
lkeavndtfdsaskeenkkknryqnilaydrtrvvlseldgvegsdyinasfidgyqerekfiatqaPlentiedfWrmvWeeessivvmltklveklkv
IHNDYlpmWPRND-LQVGRFMIKMTNMDfiVQKNIMRRSFKVADSTGKFAARTLTHYQYSQWAERGVPKSHVETYELMEMVKKSE-----KPIVVHCSNG
. | ||... . ||..... . . ..... | .|. ... .|...|.|| .|.. .||.. .|.. ..|| .|||||||.|
klkky...wpeenfeeyGrlivtleeee..eledyiirklklnkkssevetRevkhfqyteWpdhdvPekatslldllkrirksrektqsgPivvhCsaG
IGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQlYWMTLGTMYRLIKEYGFDMKIYDQQMA
.|| .|| . .|. . .... . ..| | ||...| | . .. .. . .... | ..
vGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeq.Ykfiyealleaveagdteievqdlrdr
|
subfamily_PTPRB_pd |
Subfamily PTPRB |
1043-1279 |
9.8e-36 |
118.3 |
In-house |
37-277 (293) |
alignment |
Range on Protein: 1043-1279
Range on HMM: 37-277/293.0
IDKD-HITESYAYLPEDKHRYPTVPCKPSTAVEV-IVDG--KRAPIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIH
..|| .. . . ..| || . . |.. ... . | ||..| |. ||||| |. | .||| |... ... |||. . || |
vgkdqavkaaelavnraknrytnilpydhsrvkLaalkdesgsDYinanyipgynsprefiatqGPlpetvddfWrmvwekkssiivmltqlvekgkvkC
NDYlpmWPRN--DLQVGRFMIKMTNMDfiVQKNIMRRSFKVADstgKFAARTLTHYQYSQWAERGVPKSHVETYELMEMVKKS------EKPIVVHCSNG
..| ||.. . . | ..... . .... . |..|. . . |....|.. |.. |||.. .....|... ..||||||| |
eeY...WPadeepvlyGdikvtlvaee..eledwvirelkiek...ekeerkvrqyhftsWpdhgvPektktlldfvrtvreaiektaskrPivvhCsaG
IGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQLYWM
.||. .|| . | ...| . ..... . .| |.| . |||..| ..
vGRtGtfialdrllqaieeedyvdifgivaelReeRnllvqtekqYifi
|
subfamily_Cele-PTP-6_pd |
Subfamily Cele-PTP-6 |
1056-1279 |
1.6e-35 |
117.6 |
In-house |
41-269 (307) |
alignment |
Range on Protein: 1056-1279
Range on HMM: 41-269/307.0
PEDKHRYPTVPCKPSTAVEVIVDGKRA-PIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDLQVGR
|| || |.|. . . | .|| . ||||.. . .|..||..| | ..| .||||..| .|| ..|. . .| | ..| |. . | |
ntdknryqdvkcqdkgrivvkfdglasdyihanylgiaikpkkficaqgplentqysfwamaiqekvesvimlckvielakikceqywpleegqklvfge
FMIKMTNMDFIVQKNIM-RRSFKVADSTGKF--AARTLTHYQYSQWAERGVPKSHVETYELMEMVKKSEKPIVVHCSNGIGRSMAFIGTEYLAR-QVEAD
.. .. ..| .|.. .. .||..|.|...| .||||. . . .|.| |. . |.||||| |.||| . .. .. ..
apntisvanlgakklapdedlinvttlkvdwaqksrtiqhlqwenwpdrgvpqinltainlleavrydtnpvvvhcsaGvGrsGtivaislvqdkmiaGi
PTIELTEALKHLHEHRWNGVQTNSQLYWM
.. . .. | ..| .||. | ..
nckdmkklveelrsqrhyaiqteaqylyl
|
subfamily_Urchin-PTPRB-like_pd |
Subfamily Urchin-PTPRB-like |
1058-1279 |
1.7e-35 |
117.4 |
In-house |
49-271 (288) |
alignment |
Range on Protein: 1058-1279
Range on HMM: 49-271/288.0
DKHRYPTVPCKPSTAVEVIV---DGKRAPIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYlpmWPRNDL--QV
.| ||. . ..|.. . | |... .. ...||||.|. .| .||| . ..... |||. || |. ..| || .| .
kknRyrnilpyDekrvklkkleeeagaDYinasyidgekkkkkyiatqgPladtvndfWelvyenktstivmltelveggktkCeeY...WPdadkpkny
GRFMIKMTNMDfiVQKNIMRRSFKVAdstGKFAARTLTHYQYSQWAERGVPKSHVETYELMEMVKKS---E-KPIVVHCSNGIGRSMAFIGTEYLARQVE
| . ..... ..... |.. . | ...|.||| |.. |||.|. . ||...|| . . .||.||||.|.||. || . | .||
Gsvtvtlvesk..eledfvlrkllle...kkkteleitqyqylaWpdhgvPeskapllellrqvkvanqadtgpiivhCsaGvGrtgtFialdalidave
ADPTIELTEALKHLHEHRWNGVQTNSQLYWM
.. .|........| ..| . ||| .| ..
eedyiDvagtvaklRkqRallvqtlkqYefi
|
subfamily_Cele-PTP-10_pd |
Subfamily Cele-PTP-10 |
1055-1280 |
1.1e-34 |
114.5 |
In-house |
54-282 (305) |
alignment |
Range on Protein: 1055-1280
Range on HMM: 54-282/305.0
LPEDKHRYPTVPCKPSTAVEVIVDGKRAPIHANWVPTPGHPH-RFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDL--Q
. . | || |||. .|| . ||||.| | |. |||..| |.. | ..|| | .| ||.|||. . || | .| |. . | .
iaitknryqdvpcqdqsavkldkpspsdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkveqivmlcktvelgklkcaqywpaaqgeklelk
VGRFMIKMTNMDFIV-QKNIMRRSFKVADSTGKfaARTLTHYQYSQWAERGVPKSHVETYELMEMVKKSEKPIVVHCSNGIGRSMAFIGTEYLA-RQVEA
| . ... . . .| .... | .. .. | |...| .|||| .. . ||. .. |. ||||||| ||||. . . ||. . |
sgivvenvsgskpmerdaeiqitllnltysgdq..kmsvrhlqwtewpdrgvppckltslellsairgskvpivvhcsagigrtgtivaieyilekiaen
DPTIELTEALKHLHEHRWNGVQTNSQLYWMT
| . | .| | ..| .|.. | ..
kpcppmpelvkalrdqrafsiqndvqylfih
|
subfamily_Anemone-PTP-6_pd |
Subfamily Anemone-PTP-6 |
1083-1280 |
2.3e-34 |
113.9 |
In-house |
76-272 (318) |
alignment |
Range on Protein: 1083-1280
Range on HMM: 76-272/318.0
PIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYlpmWP-RNDLQVGRFMIKMTNmDFIVQKNIMrRSFKVADsT
| ||... . . .||.|.|. |.|||| | . . |||. ...| |. . | || .. . |. ...... .. ... .. |.||| |
yinanyidGyrrkkayiaaqaPlpetieDfWrmvWeqnsavivmltqeeergkakvhry...WPskgsrsygklvvelke.evelsdyvl.refkvtr.t
GKFAARTLTHYQYSQWAERGVPKSHVETYELMEMVKKSE-----KPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQl
.. . |. |.| .|...|||.| .. .|. |.| . .||||||| |.|| || . | ....|. .... . |.| |.| |||..|
eeeesrqvrqyhytsWpdegvpesgaslldlvrqvskaqqksgagpivvhCsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqtedq.
YWMT
| .
yefi
|
subfamily_Sponge-PTP8_pd |
Subfamily Sponge-PTP8 |
1080-1276 |
3.1e-33 |
110.2 |
In-house |
73-272 (305) |
alignment |
Range on Protein: 1080-1276
Range on HMM: 73-272/305.0
KRAPIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDLQVGRFMIKMTNMDfiVQKNIMRRSFKVAD
.. | |..| . . ...|..|.|.. | .||| . ... |..|||. . || |. . | | ... . |.|...... .. . | .|..
dsdyinasyvdgykrkkkyivaqgPlkntvadfWrliveekvstivmltklveggkdkCrqYWpesktekkefgefsvelksek..tasdyieRklkisi
STGKFAARTLTHYQYSQWAERGVPKSHVETYELMEMVKK----S-EKPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNS
.. ||...|| .| . |||.. .|.. |.| . ..|..||||.|.||. .|| . ..... .... | ||.| ..| . |||
ededkesrtvlqyqltdWPdhGvpqfatsllslikrvqkdqkkdkgvpllVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkmvqtld
QL
|
qY
|
subfamily_PTPN3_pd |
Subfamily PTPN3 |
1058-1278 |
4.1e-33 |
109.5 |
In-house |
43-266 (280) |
alignment |
Range on Protein: 1058-1278
Range on HMM: 43-266/280.0
DKHRYPTVPCKPSTAVEViVDGKRAPIHANWV----PTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMwPRNDLQVG
.| || . .| |.. .... | ||.| |. | |.|||| |.. |..||| | . ... |||. || . | | . . |. |
sknryrdilpydatrvkl.kesetdyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqksslivmlttlverGrvkChqyWPe.tedeleyg
RFMIKMTNMDfiVQKNIMRRSFKVADSTGKfAARTLTHYQYSQWAERGVPKSHVETYELMEMVKKS----EKPIVVHCSNGIGRSMAFIGTEYLARQVEA
.|..|... | .|... | . . |.. | |.... || .|.. |||... . |..| |.| |.|.||||| ||||. .| | .||
efsvkceked..etksyvlrelvlkdketk.eerkilqlqylaWpdhgvPddsadflefvervrklrsgkeePvvvhCsaGigrtGvlilletalaliea
DPTIELTEALKHLHEHRWNGVQTNSQLYW
. . .... . | . |||.|| .
aepvypldivrtmrdqramlvqtasqykf
|
0051429 |
(Phosphotyrosine protein) phosphatases II |
1084-1288 |
5.2e-33 |
110.2 |
In-house |
7-226 (272) |
alignment |
Range on Protein: 1084-1288
Range on HMM: 7-226/272.0
IHANWVPTPGH---PHRFIATQSPINATCEDFWAMcMQYEVEHIVMVGRK--------VEYWKNIHNDYLPMWPRNDLQVGRFMIKMTNMDFIVQKNIMR
|.|..|...|. |.|..... | ..|..|||.. .. . .||.. . || .|. .||.... . .. ... .|.. .... ...
iNardvggygrvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseellldyil
RSFKVADSTGKFAARTLTHYQYSQWAERGVPKSHveTYELMEMVKKsEKPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIE--------LTEALKHLHE
| . . . .||...|..| .| .|||.. ||.|.. . ..|..|||| |..|. .. .|...|... .. | ||...| .
rellltlllsagearevmhlhytdwpdhgvpqea..llellellld.ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlyleeaveelra
HRWNGVQTNSQLYWMTLGTMYRLI
.| . ||| |... . |
qrpgavqteeqylflyeallellr
|
0041856 |
(Phosphotyrosine protein) phosphatases II |
1058-1281 |
7.4e-33 |
109.0 |
In-house |
3-165 (182) |
alignment |
Range on Protein: 1058-1281
Range on HMM: 3-165/182.0
DKHRYPTVPCKPSTAvevivdgKRAPIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGrKVEYWKnihndylpmwprndlqvgrfmi
||.||. ... . . |.||.. . .. |||||| | . |..||. | .. . .||.. . ||
dknrysdilpydhsr.......dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt.eelywp......................
kmtnmdfivqknimrrsfkvadstgKFAARTLTHYQYSQWAERGVPKsHVETYELMEMVKKSEKPIVVHCSNGIGRSMAFIGTEYLARQveadpTIELTE
.. |. ..|.| .| ||| |.....|.|.....|..|||| |.||. .... .. .. . |.|
.........................ellerlgiqylylpwpDhgvpd.ldelldfieevleeggpvlVHCsaGvgRtgtlvaaylmkkl.....gvslee
ALKHLHEHRWNGVQTNSQLYWMTL
|.|.. ..|...|.| .|... |
avklvrsrRpgmvitpnqyfflql
|
subfamily_PTPN12_pd |
Subfamily PTPN12 |
1083-1277 |
1.3e-32 |
107.9 |
In-house |
70-267 (290) |
alignment |
Range on Protein: 1083-1277
Range on HMM: 70-267/290.0
PIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDLQVGRFMIKMTNMDFIvQKNIMRRSFKVADStg
| ||.. . ....||.|.|. .| .||| | ....|| .||. |.|| |. . | | ..|..| | ..... . . ..... |..|| .
YinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCerYWpeegeeelefgefevtleeekav.dddflirtLkveaq..
kFAARTLTHYQYSQWAERGVPKSHVETYELMEMVKK----SEKPIVVHCSNGIGRSMAFIGTEYLARQVEAD---PTIELTEALKHLHEHRWNGVQTNSQ
. |... ..| .| ..|||.|. . ||.|.|.. ...|.||||| |.|| . | .| ....|. ..... . . .| ..| |||. |
.kesrkvyqfhYtaWPDhgvPssaksllelielvrelqesedaPlvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeq
LY
ye
|
subfamily_Cele-PTP-8_pd |
Subfamily Cele-PTP-8 |
1059-1291 |
2.9e-32 |
106.9 |
In-house |
46-276 (288) |
alignment |
Range on Protein: 1059-1291
Range on HMM: 46-276/288.0
KHRYPTVPCKPSTAVEVIvDGKRAPIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDLQVGRFMIK
. || .|. | | . | |.|| |.. ...|.| .|.|.|.| | .| | .. .||.|||. . .| |. ..|.|. . ..||.
rdryenlprcditrvkls.ddpdfyiaanvvssakykrrlicaqaPlngtieelWkmllesdveyivmlcellekGkeksaeyfPsklGekarigrlctv
MTNMDFIVQKNIMRRSFKVADSTGKFAarTLTHYQYSQWAERGVPKSHVETYELMEMVKKSEKPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEA
. . ..| . ... . . . . . .| . |||.... |.|..|. .||||||.|.|.||....| . .... | . . .
vkkkradidklvkvsllriskegeekv..ivkilhlleWdddgvPenylsplrllevlkslqkPivvhssaGvGrtgtlililialeslrlddflgirsl
LKHLHEHRWNGVQTNSQ-LYWMTLGTMYRLIKEY
|..| |.| . .||. | || . . |.| |
laklreerfkaiqtemqylyvhrcvleelllkky
|
subfamily_Anemone-PTP-2_pd |
Subfamily Anemone-PTP-2 |
1082-1278 |
7.6e-32 |
105.7 |
In-house |
85-281 (298) |
alignment |
Range on Protein: 1082-1278
Range on HMM: 85-281/298.0
APIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYlpmWPR-NDLQVGRFMIKMTNMDfiVQKNIMRRSFKVADS
| | .. . . . ||||| |...| |||| | ...... |||. .| | . | || . . |.. ... . . .. ... | .||...
dYiNAsflhaykgrnafiatqaPltetvedFWrmvteedigtiVmltnleeldktkyhky...wPdegketygeitvsllske..efadlivrklkvskk
TGKfAARTLTHYQYSQWAERGVPKSHVETYELMEMVKKS-----EKPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQ
. . |.. . ....|...|||. . .|.. |..| .||..|.||.|.||| .|| . . .|... .... ...| | ..| . |||..|
kee.kerevrqlhftsWpdkgvpenatsvldllrkvrasqqqagnkpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqteeq
LYW
.
Yvf
|
subfamily_PTPN13_pd |
Subfamily PTPN13 |
1041-1277 |
3.6e-31 |
103.4 |
In-house |
24-259 (273) |
alignment |
Range on Protein: 1041-1277
Range on HMM: 24-259/273.0
TTIDKDHITESYAylPEDKHRYPTVpcKPSTAVEVIVDGKRAPIHANWVPTP--GHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIH
..|. ..... . .|| || | | . |..... . | |... | . ...||.| |. |..||| | . ..| |.|| ..| |
kpldtcevgkkke..nkdknryrnv..lPydetrvklgdeggyinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvkc
NDYLPMWPRNDLQVGR-FMIKmtNMDFIVQKNIMRRSFKVADSTGKfAARTLTHYQYSQWAERGVPKSHVETYELME---MVKKSEKPIVVHCSNGIGRS
. | | .. |.| . .. ... ... |...| || . ..| ..| .. .| . |||.| .| ... ..... ||||||| |||||
hrywPesknkklkvsnrleve..llkvqkldgfvvralavkdsesg.esrevahlnfvkwPdhgvPssaaellqfvaevrrlqtdagPivvhcsaGiGrs
MAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQLY
..| . . .| | ....| ...| | | |||. |
Gtlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyi
|
subfamily_Cele-PTP-20_pd |
Subfamily Cele-PTP-20 |
1058-1296 |
3.9e-31 |
102.8 |
In-house |
58-287 (290) |
alignment |
Range on Protein: 1058-1296
Range on HMM: 58-287/290.0
DKHRYPTVPCKPSTAVeVIVDGK-RAPIHANWVPtpGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDLQVGRFM
| || |.| | | .. || .|||.| | || || ....| |.| | .| .| |||. .| | ..| | . | | .
kknrykdvvcndktrv.ilkdGydGdyvhanyvk..GlkamfiltqGalkdtvidiwrmvlqekvaaivmlceliedGkakceqyypekeGevltfGeit
IKMTNMDfIVQKNIMRRSFKVADST-GKfaARTLTHYQYSQWAERGVPKSHVETYELMEMVKKSEKPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIEL
. .. | ..||... . | | || | |.. | .. |..| . .. ...| |.||||| ||||. .|. | .. . ..|
vlcseed.dkdaniikktlsvrdkdsGk..ehklkhlkikswpdksvalstlallrtlrilrkasGpvvvhcsaGiGrtGtfvaievglqilldGkeldl
TEALKHLHEHRWNGVQTNSQlYWMTLgtmyRLIKEYGFDMK
. . | . | | || . | | . . ... ..| |.|
ldlvralrnsrlnsvqvdiq.ylalv....eilldlGkdfk
|
subfamily_Ptp69D_pd |
Subfamily Ptp69D |
1082-1310 |
6.7e-31 |
102.5 |
In-house |
77-303 (307) |
alignment |
Range on Protein: 1082-1310
Range on HMM: 77-303/307.0
APIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYlpmWP-RNDLQVGRFMIKMTNMDFivQKNIMRRSFKVADS
| |... . . ..||| | |..|| .||| | .. ||. |||. |. .. . | || . | | ..|. . .. ... ..|...|.
dYinasfikgykekkkfiaaqdPveatigDfWRmiaeqevtlivmlsnlteknrkkcakY...Wpiedevqygdilvklvseek..hsdyiiReldvskk
TGK----FAARTLTHYQYSQWAERGVPKSHVETYELMEMV----KKSEKPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQT
. . | .. |.| .| . ||.. .|.|.| |... |||||||.| ||| |. . | |..|. .... | |.|...| ||
keesgevedsrkvvqyhytgWkDskvPevargllklieqvrelyklnrsPivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnllvqs
NSQLYWmtlgtMYRLIKEYGFDmKIYDQQMAMFNDVVK
| . .|| . .| |... ..| ..
leqYvf.....lyralldyssy.gdtdedvddledaie
|
subfamily_PTPRK_pd |
Subfamily PTPRK |
1077-1277 |
7.9e-31 |
102.0 |
In-house |
65-267 (314) |
alignment |
Range on Protein: 1077-1277
Range on HMM: 65-267/314.0
VDGK--RAPIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYlpmWPRNDLQVGRFMIKMTNMDfiVQKNIMRRS
.|| | |... . .|. ||.|| |.. | .||| . ... |||. || . | || . . | . ... ... ...... |
idgdpssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasivmltelvevgrvkClky...WPedtevygdikvelvete..llaelvvri
FKVAD-STGKFAARTLTHYQYSQWAERGVPKSHVETYELMEMVKKSE----KPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNG
|.| . |. . |.. ..|. .|.. .||.| .|. ||||. .||||||.| ||. .|| . . .| . .... .| | | ... |
frveklargqeeirevrqfqflgWpdhdvPvsatgllklvrrvkksqeeeaGrivvhCsaGaGrtGtfiaidivldmieregvvdvfnavktlrsrkvnm
VQTNSQLY
|.|. |
veteeqyk
|
0043147 |
(Phosphotyrosine protein) phosphatases II |
1082-1279 |
1.1e-30 |
102.0 |
In-house |
6-153 (172) |
alignment |
Range on Protein: 1082-1279
Range on HMM: 6-153/172.0
APIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKveywknihndylpmwprndlqvgrfmikmtnmdfivqknimrrsfkvaDST
|.|...... .|.|||||| | . |..|||.|. .. . |||.. . .
dyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltel................................................lyd
GKFAARTLTHYQYSQWAERGVPkSHVETYELMEMVKK-----SEKPIVVHCSNGIGRSMAFIGTEYLArqveadPTIELTEALKHLHEHRWNGVQTNSQL
... |. .|.| | ||| . .|..| ... ...|..|||| |.||. ... .. . | ||.... |.|...||. ||.
pellerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml......lglsleeavalvrekRpgavqnpsqy
YWM
..
rfl
|
subfamily_Cele-PTP-1_pd |
Subfamily Cele-PTP-1 |
1084-1293 |
1.7e-30 |
101.1 |
In-house |
49-265 (290) |
alignment |
Range on Protein: 1084-1293
Range on HMM: 49-265/290.0
IHANWVPTPgHPHRFIATQSPI-------NATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHN----DYLPMWPRNDLQVGRFMIKMTNMdfIVQKNIMR
|||| | | . |.|.|||| |.| |.|| | .| .|...||.. | .| .. | |. ..|... . .| ... . .... .
iHAnrvtcp.nglrliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCakYvpesvgeelkfkgltvkCksk..ekeddvet
RSFKVAdsTGKFAARTLTHYQYSQWAERGVPKSHVETYELMEMVKKSEKPIVVHCSNGIGRSMAFIGTEyLARQVE--ADPTIELTEALKHLHEHRWNGV
| | .. |.||.....| .. |.... .|...||.|. |..||| .|| || |. . |. | ..|...|| | ..| . .
Relvvk..fddeeeftvtHsllkgWnklnvqedtktllsliqkvkasktpvivHcvdGiSrsAalaaii.lgyQkiaetsgsvkledvlkalrkqralai
QTNSQLYWMTLGTMYRLIKEYGF
... .| .. | . ..|...
tsalelafvdagivllaievldq
|
subfamily_Choan-PTP-2_pd |
Subfamily Choan-PTP-2 |
1061-1279 |
2.4e-30 |
100.4 |
In-house |
25-256 (270) |
alignment |
Range on Protein: 1061-1279
Range on HMM: 25-256/270.0
RYPTVPCKPSTAVEV---IVDGKRAPIHANWVP-TPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDLQVGRFM
|| . .| | | . | . | | ||.|. |.....||...| ..| ..|| | .. .|. |||. .| .. . | | | . ... .
RyadiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkekvkledgk
IKMTNMDFIVQKNIMRRSFKVAdSTGKfaARTLTHYQYSQWAERGVPKSHV---ETYELMEMVKKS-------E--KPIVVHCSNGIGRSMAFIGTEYLA
||.... .. ... .. ..|. | |.|..| .| ..|||... .| .|..|... . .|..||||.|.||. .| ...
ikvlalseekeegyiltrlrle.ekge..errlvHfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcsaGvgRtGtlialDiav
RQVEADPTIELTEALKHLHEHRWNGVQTNSQLYWM
| .| . ..... ...| ..| . ||. | ..
rlLeetkkvdvlaiieelRkdRmalvqhpeqyefl
|
subfamily_PTPN9_pd |
Subfamily PTPN9 |
1057-1278 |
3.4e-30 |
100.1 |
In-house |
43-281 (297) |
alignment |
Range on Protein: 1057-1278
Range on HMM: 43-281/297.0
EDKHRYPTVPCKPSTAVEVI-VDGKR--APIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYlpmWPRNDLQVG
| || | | .| | . ||.. |.||.| ... ||||| |.. |..||| | . || |||. | || . . | || .. ..
leknrytdvlcydetrvvlakvdedeasdyinanfvdGykqkkafiatqGplkktvsdfWrmvWeqevlvivmttrvvergrlkcgqy...Wpleeessa
RF-MIKMTNMDFIVQKNIMRRSFKVADSTGKfAARTLTHYQYSQWAERGVPKSHVETYELMEMVKK-----------------SEKPIVVHCSNGIGRSM
.| ....|.. .... . |.... ... . |..||.|. | . |||.| . ...|.|.. |. ||||||| ||||.
efgdlsvsnveveeeedykvrvleiknvkte.esrkvthfqflsWPdyGvPssaaslldvlekvrekqalavkelgdewkghpsgPPivvhcsaGiGrtG
AFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQLYW
.|| .. ..| |....|..|.| . | .||. | ..
tfitldiclsrleevgtvdvvetvkllrtqrafsiqtpeqyef
|
subfamily_Sponge-PTP10_pd |
Subfamily Sponge-PTP10 |
1025-1277 |
5.1e-30 |
99.4 |
In-house |
16-268 (287) |
alignment |
Range on Protein: 1025-1277
Range on HMM: 16-268/287.0
HKPAKFYNTTIENVNVTTIDKDHITESYAYLPEDKHRYPTVPCKPSTAVeVIVDGKRAPIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHI
.| . ... .. | ..|..| . | .|| |. . . | .. . . | | .. . . ..||...||. | .|| . . .|. |
akgnegfknqftvleqvtqredevthniasqnkdknRltqilvpdnyrv.llkgehpdyinavfidgykekkafiiaesPmfntarnfWkliddrnvtai
VMVGRKVEYWKNIHNDYlpmWPRND-LQVGRFMIKMTNMDfiVQKNIMRRSFKVADSTGKFAARTLTHYQYSQWAERG-VPKSHVETYELMEMVKKS---
||. .. | ... .| || .. . .| . |...| . |... . | ..| .. . . .... ||. .| ..| |.. . ||.|.
vmlcqekendeevcyqy...WpeeksvvlGeyniellnee..vnagyierklevknknkagdkqqvkqyqitnWdstgkvtepqtillvieemyktqrkr
-EKPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQLY
. .||||||...||| |. . .... . .|.. . ||. . . ||| .|
gntsivvhCsdtvGrsamfcaaattinkckteGviDvfqvlksqriqkpgsvqtveqyk
|
subfamily_Nvec-PTP-2_pd |
Subfamily Nvec-PTP-2 |
1088-1278 |
6.8e-30 |
99.1 |
In-house |
44-233 (250) |
alignment |
Range on Protein: 1088-1278
Range on HMM: 44-233/250.0
WVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNiHNDYLPMwpRNDLQVGRFMIKMTNMDfiVQKNIMRRSFKVADSTgKFAAR
.. . . |||||.|..|| |||| | ...... |||. .| |. ..|.|. . . | .... . . . ... | .|.. . | |
flhgyderkafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqywPv..ekaekyGdvtvsllske..efadytkrklklskak.kader
TLTHYQYSQWAERGVPKSHVETYELMEMVKKSE-----KPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQLYW
.. .... .| ..|||. ||.. |..|. .|..|.||.|.||| ||| . . ... . .... . .| | ..| . |....| .
ivrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidavlerlkkekvvdvfkvikvlrkdrphavesleqyvf
|
subfamily_Sponge-PTP11_pd |
Subfamily Sponge-PTP11 |
1083-1277 |
2.9e-29 |
96.9 |
In-house |
78-273 (290) |
alignment |
Range on Protein: 1083-1277
Range on HMM: 78-273/290.0
PIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDlqVGRFMIKMTNMDfIVQkNIMRRSFKVADSTG
|.| .. . ...||||.|.. | ||| . .| .| |||. .| |. . | | . .. .| | ||..| ... ....| ..| ...
yinAcyikgykekkqyiatqgpvsntlvdFWkliwqekvtiivmltniieegkvkCqqYWpdsdtka..ygefsikllnee.tln.eyierklevknkns
KFAARTLTHYQYSQWAERG-VPKSHVETYELMEMVK----KSEKPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQLY
. |....|.|| . | . | |.. . . . ||.| . ...||||||...||| |. .. ... . |.. . ||.. . . |||. |.
agakqsvtqyqitnwdstgkvtnpqtillvieemyktqrkrgntsivvHCSdtvgrsavfcaaattinkcktegvidvfqvlksqRiqkpgsvqtvqqyq
|
subfamily_PTPN5_RR_pd |
Subfamily PTPN5_RR |
1057-1277 |
1e-27 |
92.0 |
In-house |
29-258 (274) |
alignment |
Range on Protein: 1057-1277
Range on HMM: 29-258/274.0
EDKHRYPTVPCKPSTAVEVIVDGKRAP----IHANWVPTPGH-PHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDLQ
. | || |. . . | . . ... | ||.. ... . ..||| |. | .||| | | ||. |||. . | .. . | | ...
qtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneqkCavyfPdaedyeis
VGRFMIKMTNMDFIVQKNIMRRSFKVADSTGkfaARTLTHYQYSQWAERGVPKSHVETYELMEMVKKSE-------KPIVVHCSNGIGRSMAFIGTEYLA
..... . . ... |.. . .. |...|| |..| .. .|.. . .|.. |..|. |.||||| |||| .||...
erygdveikvekiverndysvrklvlkyler...ersvkhywytdWPdhksPddantlldlvleveesreeenaklapvvvhCsaGiGrtGcfiaisiav
RQVEADPTIELTEALKHLHEHRWNGVQTNSQLY
||.... .... . .| .| |||..|
rqlreeivvdvlkivcnlrldrGGmvqtseqye
|
subfamily_Urchin-PTP-7_pd |
Subfamily Urchin-PTP-7 |
1078-1276 |
1.1e-27 |
91.8 |
In-house |
74-268 (315) |
alignment |
Range on Protein: 1078-1276
Range on HMM: 74-268/315.0
DGKRAPIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYlpmWPRNDLQVGRFMIkmTNMDFIVQKNIMRRSFkv
| . . ||... ...|.||.|.| |. .||| . ..... .|||. || |. . | || ... |.. . | .. |.... |..
dphsdyvnanfidGynkkrryiaaqgpnvasvkdfwrlvfeedigkivmltnlvegekrkaeky...wpdkkviyGkitv..trkseevnteytvrtl..
aDSTGKFAARTLTHYQYSQWAERGVPKSHVETYELMEMVKK----SEKPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTN
. . |.. ..|. | . ||||. . .|. ||. | .||||||.|.||. .|| . . |.||. |.. .... . . | . ||.
.svvfgdnirevvqlhytswpdmgvpkytiplmnlirtvkqhhtnsvgaivvhcsaGvGrtGtfitldavldqaeaenaidvynfitgvrqnrikmvqva
SQL
|
eqy
|
subfamily_PTPRG_pd |
Subfamily PTPRG |
1078-1279 |
4.5e-27 |
89.5 |
In-house |
70-279 (563) |
alignment |
Range on Protein: 1078-1279
Range on HMM: 70-279/563.0
DG---KRAPIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMwpRNDLQVGRFMIKMTNMDFIVQK---NIM
| | | ||.. . . ||||| |.. |..||| | . .|. |||. || .. . | | . ...| . ..... . .. ...
pgkkkklDYinAnyidGyqkskafiatqgplkdtfddFWrmiWeqnvaiivmitnlvergrrkcdvYWPk..desetygalqvtlieeevlalytvrtlv
RRSFKVADSTGKFAARTLTHYQYSQWAERGVPKSHVetYELMEMVKKSE------KPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEH
. .|. . . .. ..|.|..| . |||.. . ..|. ..|.| |||||||.|.||. .| . | .|.... .... . |||.. .
iknlklkkkkqcdteklvrqyhytkWPdhgvPehsl..pvLifvkkssaankaeaGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraq
RWNGVQTNSQLYWM
| . |||. | ...
RnflvqteEqYifl
|
0049260 |
(Phosphotyrosine protein) phosphatases II |
1091-1279 |
7e-27 |
89.4 |
In-house |
4-142 (152) |
alignment |
Range on Protein: 1091-1279
Range on HMM: 4-142/152.0
TPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLpmwprndlqvgrfmikmtnmdfivqknimrrsfkvadstgkfaartlt
..|..||||| | . |..||| | .. . .|||. . .| .| .. |
gyampfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi................................................
HYQYSQWAERGVPKSHVETYELMEMV----KKSEKPIVVHCSNGIGRSMAFIGTEYLArqveadPTIELTEALKHLHEHRWNGVQTNSQLYWM
.|.. .| |||... ..|.... .....|..|||| |.||. ... .. ..| ||.... |.|...|.. .||..
qylhlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpgqlrfl
|
subfamily_Urchin-PTP-6_pd |
Subfamily Urchin-PTP-6 |
1083-1276 |
7.8e-27 |
88.5 |
In-house |
73-265 (515) |
alignment |
Range on Protein: 1083-1276
Range on HMM: 73-265/515.0
PIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDLQVGRFMIKMTNMDfiVQKNIMRRSFKVADSTG
. | .|. . .||.| | .|. .||| . .|..| |.|| .. | | | | | . .. | . ... .. . ..| ..| .
yfnasyipsfdndkayiasqgPnkasvddfWrlvlqenvttiamvtklkegdkikcgkyWPdkpgdsvkfGsikvelvsle..actggikrkltvlkgdd
kfaARTLTHYQYSQWAERGVPKSHVETYELMEMVKKS----EKPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQL
.||.| ... .| ..|||| |. || . . |...||| |.|| .| . ... .... . .. . ..| |||. |
...srtvtqfhfteWPdkGvpkhtssllklikevkadhgqythpliihcsaGvGrtGvvisidsvvahakttrmvdvfnfvtnirqkrpylvqtqeqy
|
WSN |
Domain of unknown function |
27-93 |
9.4e-27 |
82.7 |
Pfam-A |
2-68 (69) |
alignment |
Range on Protein: 27-93
Range on HMM: 2-68/69.0
KPTDYLDHITIIAHIANGITLQAGLMNGTIQIDEVVGEMLNLGSANVSDLINYKPDKILELIKKLKE
.....|....|||...|||.|||||.||.| ||.|. |.||.||...|.|.....||. | ..||.|
elqtvleklsiiaRvtngIyLqaglingsipiddviaELLnigssslsqllkidvdklkeklnklse
|
subfamily_PTPN23_pd |
Subfamily PTPN23 |
1091-1277 |
1.4e-26 |
87.9 |
In-house |
79-270 (288) |
alignment |
Range on Protein: 1091-1277
Range on HMM: 79-270/288.0
TPGHPhRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDLQVGRfmIKMTNMDFIVQKNIMRRSFKVADsTGKFAARTLT
.|| | |||||.|.. | ||| | .. .. |||. | | |. . | | . . | ...| . .. ..| .|. .. | ....
spgcP.dfiatqaPlqstlnDFWlmvyeqkssviVmllskeelgkpkvdrYwPedkgetvkfgd..lsvtlksvretethvervlklet.ldadavksvs
HYQYSQWAERGVPKSHVETYELMEMVKK--------SEKPIVVHCSNGIGRSMAFIGTEYLARQVEADPTI-ELTEALKHLHEHRWNGVQTNSQLY
| |. .|.| |||.| . .... |.. |..|.||||| |.||. .| .|..|... . .. . ...| | | . ||...||
hlqltsWpelGvPasPetllqfldevesayeavqrksktPlvvhCsaGvgRtgvfalvyaavrelekgnglldiiqvvsrlreqRrfmvqekeqlk
|
subfamily_Cele-PTP-15_pd |
Subfamily Cele-PTP-15 |
1057-1290 |
7.3e-26 |
85.8 |
In-house |
36-273 (285) |
alignment |
Range on Protein: 1057-1290
Range on HMM: 36-273/285.0
EDKHRYPTVPCKPSTAVeVIVDGKRAPIHANWVPTPGHPH-RFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDLQVGRF
| || | | | | |. . | |||.|. ||. . .|.|| |. | ||| | | .. ...|. .| . | | . ...|..
pdlnryadvrcieetrv.vlknhdrdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyypeklgevvkfgky
MIKMTNMDFIVQKNIMRRSFKVADSTGK-FAARTLTHYQYSQWAERGVPKSH---VETYELMEMVKKSEKPIVVHCSNGIGRSMAFIGTEYLARQVEADP
| .|. . .. | .. . | | | .. |. .| |. .. |. ||||.|||| |.||. .|.| .| . .. .|
eitlteckeeaiagtilnaltvintedasseplymnhvqvpwwpdqlapedarpmielykwvkkvnpkekpicvhcsagvgrtatfvgidyatirimenp
TIELTEALKHLHEHRWNGVQTNSQLYWMTLGTMYRLIKE
||. . .. .. |.. ||. |. .. . | .| |
niemldivremramrfqavqshmqflflyvvlmeyfige
|
subfamily_Urchin-PTP-1_pd |
Subfamily Urchin-PTP-1 |
1080-1277 |
8e-26 |
85.6 |
In-house |
71-267 (315) |
alignment |
Range on Protein: 1080-1277
Range on HMM: 71-267/315.0
KRAPIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDLQVGRfmIKMTNMDFIVQKNIMRRSFKVAD
.. | | ... . . .||.| | .|. .||| | .|..| |||| | | | . | | . . | ||.. .. . . . | . . .
dsdyinasyiksvdddkayiasqgPlkasvddfwrmvlqekvttivmvtkkqegdkikcrqywPdrkadsvefGs..ikvellsleadtdgvarklvtrk
STgkfAARTLTHYQYSQWAERGVPKSHVETYELMEMVKKS----EKPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQ
| . ||.| .|. .| ..||.| .|. || . | ...|||| |.||. .| . |.. .... . .| | ..| |||. .
se...esrtvtqfqftewPdkGvdkqtssllklikevkadngkkefsllvhcsaGvGrtGvvisidevvaqikrtrsvdvfnfvknlrakrpylvqteee
LY
ya
|
subfamily_PTPN1_pd |
Subfamily PTPN1 |
1059-1279 |
8.7e-26 |
85.3 |
In-house |
35-263 (290) |
alignment |
Range on Protein: 1059-1279
Range on HMM: 35-263/290.0
KHRYPTVPCKPSTAVEvIVDGKRAPIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPR-NDLQVGRFMI
. || | . .. . ... | |. | . ...| || |. |.. || | . . .||. . || .. .| |. . . |.. .
lnryrdvspydhsrik.leradndyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvvekeqikcaqywPqgeeekellledtkl
KMTNMDFIVQKNIMRRSFKVADSTGKfAARTLTHYQYSQWAERGVPKSHVETYELMEMVKKS------EKPIVVHCSNGIGRSMAFIGTEYLARQVEADP
|.. . .... ..| ... . . . .|...|. | .|.. |||.| ... |..| | |.||| ||||| .|. . . ..|.
kvkliseerksyytvrllelenlktq.etreilhfhyttwpdfgvpespaaflkflfkvresGslssdvGpavihcsaGiGrsGtfclvdtclvliekkd
T---IELTEALKHLHEHRWNGVQTNSQLYWM
... . | .| ..| .|| || .
dlssvdikkvllelrkyrlGliqtadqlrfs
|
subfamily_Urchin-PTP-8_pd |
Subfamily Urchin-PTP-8 |
1084-1281 |
9.2e-26 |
86.0 |
In-house |
56-249 (284) |
alignment |
Range on Protein: 1084-1281
Range on HMM: 56-249/284.0
IHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGrkveywKNIHNDYLPMwpRNDLQVGRFMIKMTNMDFIVQknIMRRSFKVADSTGK
| | .. .....|||| | . | .||| | .|.. ||.. |. .| | . . . .|| .|.. .. . . |...... . .
inasfitGyqrkdkyiatqGPldntladfWrmiweyncstivllt......kdkcsqywpl..kivikeerfkvkvdsveesee..yvvrdielsedgke
FAARTLTHYQYSQWAERGVPKSHVETYELMEMVK------KSEKPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQLY
|... . . | . |||.. .. |.. |. . ...|||||| |.||. ..| . | ... . ... . .. | . | . || | .
kdirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrtgvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqyk
WMTL
..
fiys
|
subfamily_Urchin-PTPRA_pd |
Subfamily Urchin-PTPRA |
1041-1281 |
1.2e-25 |
85.6 |
In-house |
44-285 (319) |
alignment |
Range on Protein: 1041-1281
Range on HMM: 44-285/319.0
TTIDKDHITESYAYLPE--DKHRYPTVPCKPSTAVEV-IVDGKR--APIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGrkveywK
. . . . ..| |.. || |. . . | . ..|. | | .| .. ..||.| | . | .||| | .|.. ||.. |
cklgvnladqtfanldqnkdknriinilafdknvvklerliGeefsdyinasfvtGyqrkdkyiaaqGPldntladfWrmiweyncstivllt......k
NIHNDYLPMwpRNDLQVGRFMIKMTNMDFIVQknIMRRSFKVADSTGKFAARTLTHYQYSQWAERGVPKSHVETYELMEMVK------KSEKPIVVHCSN
. .| | . . . .|| .|.. .. . . |...... . . | .| . . | . |||.. .. |.. |. . ...||||||
dkcsqywpl..kivikeerfkvkvdsveetae..yvvrdielsedgkekdirkitqfhflGwpdvGvpdypsdlmrlvkkvrhltskenhranivvhcsa
GIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQLYWMTL
|.||. ..| . | ... . ... . .. | . | . || | ...
GvGrtGvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiys
|
subfamily_PTPN6_pd |
Subfamily PTPN6 |
1056-1278 |
2.1e-25 |
84.3 |
In-house |
96-288 (306) |
alignment |
Range on Protein: 1056-1278
Range on HMM: 96-288/306.0
PedkhryptvpckpstavevivdgkrapihanwvptpghPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDLqVGRf
...|||| ...| .||| | .| . . |||. ..|| |. | | ... |.
s......................................dksyiatqgclettvsdFWrmvwqensrvivmttkevErgkekCarYWPdeeekee.yGk.
mIKMTNMDFIVQKNIMRRSFKVADSTGKFAARTLTHYQYSQWAERGVPKSHVETYELMEMVKKS--------EKPIVVHCSNGIGRSMAFIGTEYLARQV
|..||.. ... . |...|. . | .|.. .|.. .| . ||||. ...| |.. . |||||||.|||| .|| .. | ...
.isvtnvseksladYilRelsvskkkkkkeerevfqyhfksWPdhgvpkdpgavLdfledvnrkqeeleeaeagpivvhCsaGiGRtGtfiviDillkli
E---ADPTIELTEALKHLHEHRWNGVQTNSQLYW
| | |.. .. | ..|.| |||..| .
ekkgldadidiqklvksvreqrsglvqteqqykf
|
subfamily_Urchin-PTP-5_pd |
Subfamily Urchin-PTP-5 |
1084-1278 |
2.8e-25 |
84.1 |
In-house |
82-275 (297) |
alignment |
Range on Protein: 1084-1278
Range on HMM: 82-275/297.0
IHANWVPtpGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIhNDYlpmWPRNDLQ-VGRFMIKMtnMDFIVQKNIMRRSFKVADSTG
. | .|. | ||.|.|| | .|| .||||| ....| |||. . | |. | |. . . | ... . .. ..|...|. .
vnasfvk..gnkhrlittqmPmkatvadfWamvldeqvstivmlnddnerdkkc.ary...WsdkgvttfGdvsvvl..lsvsereGfikrelevtkgka
KfAARTLTHYQYSQWAERGVPK--SHVETYELMEMVKK-----SEKPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQ
| | | . ||. .| .. |.. | .|.. |.| .| |..|||..|.|| .. . ... . .... . .|.| ..| . |||. |
k.arrvvkqyqfveWPdkaverkdsassllklisevrkdfsqnaegPllvhclaGvGrtgvlltidsvvaeakrekevdifglvkklrqerpylvqtkeq
LYW
.
ykf
|
subfamily_Sponge-PTP5_pd |
Subfamily Sponge-PTP5 |
1085-1276 |
3e-25 |
83.7 |
In-house |
61-255 (283) |
alignment |
Range on Protein: 1085-1276
Range on HMM: 61-255/283.0
HANWVP---TPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMwpRNDLQVGRFMIKMTNMdfIVQKNIMRRSFKVADST
| ..| . ...|..|||.. | ||| | . .. |||. . | . | | | . | | . . . .. ... . . ..
navfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekitaivmltklqedlrikCsqyWPk..rGsedyGeftvtlrke..ttsnsfiikelllrvns
GKFAARTLTHYQYSQWAERGvPKSHVETY---ELM-EMV-KKSEKPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQL
.. |.|||. .| | | ... ... ... .. . |||||||.||||. .||. .. .. ... . .| . |.| ||| |
sakstlllahyqvidWleyg.eqaiinslvkfnkvislqteskkgPivvhCstgiGrtavfiaasasvkdaltesvvdvfavvkimreqrmmavqtldqy
|
subfamily_PTPRA_pd |
Subfamily PTPRA |
1087-1291 |
4.2e-25 |
83.3 |
In-house |
92-294 (330) |
alignment |
Range on Protein: 1087-1291
Range on HMM: 92-294/330.0
NWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYlpmWPRND-LQVGRFMIKMTNMDFIVQKNImrRSFKV---ADSTG
.. . ..|||.| | . | |||| | ... |||. | .. . | || . . | ... .. .|. . | | | .|.|
sfidGykekdkfiaaqGPkeetvedfwrmiweqksativmltelkerkeekcaqy...wPdeGlvtyGnirvevedetvlvdytv..rkflvqqlpdatr
KFAARTLTHYQYSQWAERGVPKSHVETYELMEMVKKSE----KPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQLYW
. ..| .. . . | . ||| . .|.. ||| . ||||||| |.||. .|| . . .|.|. ... |..|.| | . |||. | .
ekksrlvrqfhftswPdvGvPfepiGmlkllkkvkklnqqsagpivvhcsaGvGrtGtfivldavlervkaerkvdvfefvkrlrlqrpqmvqtdeqyef
mtlgtMYRLIKEY
.|. ..||
.....iykvlley
|
subfamily_Cele-PTP-11_pd |
Subfamily Cele-PTP-11 |
1052-1314 |
4.3e-25 |
83.1 |
In-house |
38-301 (312) |
alignment |
Range on Protein: 1052-1314
Range on HMM: 38-301/312.0
YAYLP-EDKHRYPTVPCKPSTAVEVIVDgKRAPIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLP-MWPRND
|.| | ||| . | . | . ||||.| .| ||..||.|.. || || ... |... || . |. . |
taflkfkdlnrypniqcwdrgrftlagd.enfyihanfvkictkperfvctqgplentcthfwqlalslgstsiillcgfvedgsekcakyisdivgfvd
LQVGRFMIK---MTNMDFIVQKNIMRRSFKVA-DSTGKfaARTLTHYQYSQWAERGVPKSHVETYELMEMVKKSEKPIVVHCSNGIGRSMAFIGTEYLAR
|. | . .. . .| | .|| .||. | |||.. | . |.| | .. |. ||| ||.. ||| |.||. ... | .
ledhrvyteycteieiggkskdkithrvlkvvvkatgq..esklnhyqwaswpdhgmpdscdtalrllsavkkdkkpviahcsagvgrtgtlaliesmia
QVEADPTIELTEALKHLHEHRWNGVQTNSQlYWMTLGTMYRLIKEYGFdMKIYDQQMAMFNDVVKRLEA
. .. ... | | |.. | | ..| .. .. |. .| .|... |... ...|
alrhprkqnvkdsfvllrkdrarsvrvfpq.yvyalrcvleflyskgl.ykrneqewtkfketyakika
|
0036282 |
(Phosphotyrosine protein) phosphatases II |
1084-1278 |
2e-24 |
81.6 |
In-house |
5-161 (174) |
alignment |
Range on Protein: 1084-1278
Range on HMM: 5-161/174.0
IHANWVPTPGHPHRFIATQSPINatcedFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMwprndlqvgrfmikmtnmdfivqknimrrsfkvadsTGK
|.|... . |.||.| | . ||.|. .. ....||. . .| . .| |. . .
inaspldlsyitprliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe....................................lre
FAARTLTHYQYSQWAERGVPKSHVeTYELMEMVKKS-----EKPIVVHCSNGIGRSMAFIGTEYLARQVEaDPTIELTEALKHLHEHRWNGVQTNSQLYW
. |. .|.| | .||| ... .|... |.. ..|..|||| |.||. .... .. |. . .... . .. |. .| ..||| ||...
dlerlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtpsQyrf
|
0046846 |
(Phosphotyrosine protein) phosphatases II |
1082-1278 |
9.5e-24 |
79.5 |
In-house |
13-164 (176) |
alignment |
Range on Protein: 1082-1278
Range on HMM: 13-164/176.0
APIHANWVPTPghphRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDLqvgrfmikmtnmdfivqknimrrsfkvadst
|.||.. .. |.|||| |.. |..||..| .. ....|.. ||. . .| | . ....
dyinanlilgs....rpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgi...............................
gkfaartltHYQYSQWAERGVPKShVETYELMEMVKKSE---KPIVVHCSNGIGRSMAFIGTEylarQVEADPTIELTEALKHLHEHRW-NGVQTNSQLY
.|.. | . ||| . .||.|.... .|..|||| ||||. ... .| . . . |||... |.|. . ||| .|..
.........qylhlpwpDhgvpdl.elllellefirealkeggpvlVHCsaGigRtgtlvaay....llelekglsveealalvreqRplgavqtpeQyr
W
.
f
|
subfamily_Choan-PTP-3_pd |
Subfamily Choan-PTP-3 |
1057-1278 |
2.8e-23 |
77.1 |
In-house |
39-268 (287) |
alignment |
Range on Protein: 1057-1278
Range on HMM: 39-268/287.0
EDKHRYPTVPCKPSTAVEVIVDGKR--APIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWpRNDLQVGR
| || | | | . .|. . | ||.|.. . ..|||.|.|| || ||| . .. .. .... |.|| .. | | . ..||
vkknryadvlPiddtrvllsaegelGsdyinanyvasytddeafiaaqgPiaatvrdfwravletrsasvitmtreveearlkcykywPer.evPmrvGG
FMIKMTNMDFIvQKNIMRRSFKVADSTGKfAARTLTHYQYSQWAERGVPKSHVETY-------ELMEMVKKSE--KPIVVHCSNGIGRSMAFIGTEYLAR
. . . . | . . |.....| .. || . ... .| ..... . | . .|. .... |.|||.. ||||| .. | | .
ysvvlldydik.ePeygvralrlidletr.earvvkqldllswPdkvlaPtavglirfvldvkqhielardasevGPlvvhddvGiGrsGillatlvlvs
QVEADPTIELTEALKHLHEHRWNGVQTNSQLYW
. | .. . .. .| |.| ||. ||
rledlGrvdvaavvirlreyraalvqavvqlrl
|
subfamily_Urchin-PTP-3_pd |
Subfamily Urchin-PTP-3 |
1046-1277 |
4e-23 |
77.1 |
In-house |
36-278 (325) |
alignment |
Range on Protein: 1046-1277
Range on HMM: 36-278/325.0
DHITESYAYLPE--DKHRYPTV-PCKPSTAVEVI--VDGKRAPIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEvEHIVMVGRKVEYWKNIHND
| |. | .|| .| |.. | . . | .| . |.. | |... . . |.|.|.| || .|.| . .... .|.| ... |.
dgiakkvamkpenkaknrfknvvaldksrvvletkkddpssdyinasylrddkkkdvflaaqaPltatindlWrlvldWr.csvvvvlneldlgkdrcav
YLPMWPRNDLQVGRFMIKMTNMDFIvqKNIMRRSFKVADSTGkFAARTLTHYQYSQWAERGVPKSHVETYELMEM-------VK---KSEKPIVVHCSNG
| | . . | . .|. .. | . . | ..| . . .|.. .|. | . ||.| .... |. |. ||.||||.|
ywpkemgksktfGglevklrtieei..sdyvhrvldvkqvkk.GetrsvkqfqlqswddmGvqkrpatlisilqlvkavservtantkastpilvhcsaG
IGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQLY
.||. .|| .. .| . ... . .|.| ..| . |.| |
vGrtGvfislysalakvieesrvdifgfvkklrkdrpsmvetvdqyi
|
subfamily_PTPN14_pd |
Subfamily PTPN14 |
1093-1276 |
5.4e-23 |
76.4 |
In-house |
90-285 (300) |
alignment |
Range on Protein: 1093-1276
Range on HMM: 90-285/300.0
GHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMW--PRNDLQVGRFMIKMTNMDfiVQKNIMRRSFKVADSTGKfAARTLT
|. . .|..|.|.. |..||| | . .|. |||. .. | |. |.| .. .. |.| . . . .. ...|. | ||.
gkersyivaqgPleltvqdfWqmvWeqgvqlivmlteeeedgkeksfkyfPkleskkktvefgkfkvttkfse..dsdsvittglklkhlpsk.eertvw
HYQYSQWAERGVPKSHVETYELMEMVK-------------KSEKPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQL
| || |...|||. . . .|.|. .|. |..||||.|.||. | .. | .| . .|.. ..|..| | | ||| .|
hlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseveskeskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLreqrmllvqtlaqY
|
subfamily_Cele-PTP-9_pd |
Subfamily Cele-PTP-9 |
1106-1276 |
5.5e-22 |
73.1 |
In-house |
38-210 (255) |
alignment |
Range on Protein: 1106-1276
Range on HMM: 38-210/255.0
NATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDLQVGRFMIKMTNmdfiVQKNIMRRSFKVADSTG-KFAARTLTHYQYSQWAERGVPK
| . |. . .| . | .||.. | .. . |.|. . |.. . |. ... | .. | | ..|..||.| | |. |.
sltvdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdeklkladvnvtttk....ssadvvlrtleitstlgekkkthtvkhysykGWieknaPe
SHVETYELMEMVKKSeKPIVVHCSNGIGRSMAFIGTEYLAR----QVEADPTIEL--TEALKHLHEHRWNGVQTNSQL
| ... .|..| |..|||||.||||| ||. .|.. . ... .|.|| . |..| ..| ..| ||
lareilnilkvvrds.ksvvvhCstGiGrsaafvlaelvyqkmirsldttetveldylslleelrskrkraihtPlql
|
subfamily_Sponge-PTP9_pd |
Subfamily Sponge-PTP9 |
1082-1277 |
2.4e-21 |
70.7 |
In-house |
71-283 (301) |
alignment |
Range on Protein: 1082-1277
Range on HMM: 71-283/301.0
APIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDLQVGRFMIKMTN----MDFIVQK---------
| |... . ..|||.|.|.. | ||| . .|. . .|||| . | |. . | | .. ..| | ....| ||....
eyinasyidgysekkkfiaaqgpmkktlvdfWrliwqekpvsivmvtnlkegtkskceqywpnseaeseefgpftvtlvneqvyPdfvirqlnvkiqdgs
--NIMRRSFKVADSTgkfAARTLTHYQYSQWAERGV---PKSHVETY--ELMEMVKKSEKPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKH
. . |.||| . ...... .| .| . || |. .. .. | . |.|||||....|| .. . |. |. ... . |
nngyierkfkvksdk...sswdvlqlqvtdWpqdGvvreprtvLqviddvihrqqkigggpvvVHCSdtVsrsGvYcsvsiglEQckaegVVdvfqvtka
LHEHRWNGVQTNSQLY
. . |.| |
vrrskpgaVtTLeqyt
|
subfamily_CG7180_pd |
Subfamily CG7180 |
1084-1275 |
3.1e-21 |
70.3 |
In-house |
73-278 (296) |
alignment |
Range on Protein: 1084-1275
Range on HMM: 73-278/296.0
IHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKnIHNDYLPMWPrnDLQVGRFMIKMTNMDFIvqKNIMRRSFKVADS---
| | .| . ... .| |. | . | ..|| . . |.. .|.. .. .. | ..|.| | | ......... |. | ||.
inavyvdsflkkkeyivteapkketvdefWrlvydeeisavvvLtktfdfak.mypsywpnks..keqygeifveiveekqy..anlkirtfkltkkiva
------TGKFAARTLTHYQYSQWAE-RGVPKSHVETYELMEMVK----K-----SEKPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHE
| |.....|. .| || | ||...|. | |.|.||..|.| .|| .... . .|| . ... ||.| | .
lteqekqvkaetRivklfqlteWeledkvPlstnalielrrrvrlwrekvdedpeegPvvvvssdGasRsGvylaidanlelvekeeevdvFeavktlrr
HRWNGVQTNSQ
.| . |.. .
sRpqLvenvee
|
subfamily_Cele-PTP-13_pd |
Subfamily Cele-PTP-13 |
1056-1275 |
6.8e-21 |
69.2 |
In-house |
37-257 (281) |
alignment |
Range on Protein: 1056-1275
Range on HMM: 37-257/281.0
PEDKHRYPTVPCKPSTAVEVIV--DG--KRAPIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDLQ
. | || .|| . |.. | ||||.. .| . .| || | . | ||| | | . |||. . .| .. .|.| . ||
nnkknrylnipcldisrvqlkvkmpnknstdyihanyirspflkrgyiltqgpkketradfwrmiwqenttaivmlcqfletnrekcaeyfprnahcclq
VGRFMIKMtnMDFIVQKNIMRRSFKVADStGkfAARTLTHYQYSQWAERGVPKSHVETYELMEMVKKSEKPIVVHCSNGIGRSMAFIGTEYLARQVEADP
. .. .. | |.| .. .... | .| .||. . .| . ||.| ... .. | |.||| |.||| ... | . . .
fdklsvsy..edstvnkslvttrlnlsye.g..etrlithwlwkewpdwqvpessevmlkilrkirarstppvihcsagvgrsgtlmaveialqsihshf
TI-ELTEALKHLHE-HRWNGVQTNSQ
|. .. . . ||. | ||| |
tlpdikqivshlrvtgraasvqtlqq
|
subfamily_Sponge-PTP6_pd |
Subfamily Sponge-PTP6 |
1031-1278 |
7.4e-21 |
69.1 |
In-house |
22-270 (439) |
alignment |
Range on Protein: 1031-1278
Range on HMM: 22-270/439.0
YNTTIENVNVTTIDKDHITESYAY-LPEDKHRYPTVPCKPSTAVEV-IVD--GKRAPIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVM
.. |..| | | |. | . | || | | | . . . | ||.. .. .|||| | . |..||| . .. . .|||
fkeifekinstspdyaciaslaaqeydqtknrykdvgafdhtrvtlqeipgvphshyinanyikGyyddklyiatqgpkkettddfwrlviekktvtivm
VGRKVEYWKnihndylpMWPRNDLQV-GRFMIKMTNmdFIVQKNIMRRSFKVADSTGKF-AARTLTHYQYSQWAERGVPKSHVETYELMEMV-----KKS
. || .| || .. . | .... | | . | ||| . . ||. ...| | .. || ... . |.
ltnlvesyk........ywpsdaevcygdiavrvdr..nielpnyvirgfkvfnerdttekertvlqfhyiawpdknvpaqashvldflrainsandkee
EKPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQLYW
|.||||| |.||. . | . |. .. ... .| |...| . ||. | .
ygpvvvhcsagvGrtGtiialdialeqlklenkvdikgivkvlrkqrkqmvqalcqyvf
|
subfamily_Anemone-PTP-4_pd |
Subfamily Anemone-PTP-4 |
1092-1278 |
1.4e-20 |
68.5 |
In-house |
41-230 (237) |
alignment |
Range on Protein: 1092-1278
Range on HMM: 41-230/237.0
PGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRnDLQVGRFMIKMTNMDFIVQknIMRRSFKVADSTGKFAARTLTH
| |...||.| |....|.||| | | |||. .| . .| | . | . . .. . . . ||. .. . . | .
dgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpstdq.paaygvltvslkkkeefsd..ytvrslllskrltlkevrlihq
YQYSQWAERGVPKSHVETYELM-EMVKKSEK-----PIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQLYW
||.. | .||||. . .....|.. | ..||| |.||. |. . . || . ... . .. . | | .||. | .
yqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlrqakekkvvdiynyvysieedrpyiiqtkdqyvf
|
0051082 |
(Phosphotyrosine protein) phosphatases II |
1083-1278 |
4e-20 |
67.4 |
In-house |
5-144 (151) |
alignment |
Range on Protein: 1083-1278
Range on HMM: 5-144/151.0
PIHANWVPTPghphrFIATQSPinatCEDFWAMCMQYEVEHIVMVGRKVEYWknihnDYLPMWPRNDlqvgrfmikmtnmdfivqknimrrsfkvadstg
.|....| ..... | .||... .. . .||.. ..|. . .|...
yinfsyvtgg.....lyrsggp....ladflellkelgiktivnlrseeerg.....ycpeylpelg.................................
kfaaRTLTHYQYSQWAERGVPKSHVETYELMEMVKKS-EKPIVVHCSNGIGRSMAFIGTEYLARQveadptIELTEALKHLHEHRWNGVQTNSQLYW
....|... | . |.| | . |..|.. . ..|..|||| |.||. .... .... . | |||......|.. ||.| | .
....ievlhipildwpdpglplsfdavleflellldkkngpvlvHCsaGkgRTGtlvalylmllg......vsleealeeyrlkrpgvvqpnqqflf
|
0044763 |
(Phosphotyrosine protein) phosphatases II |
1081-1280 |
4.5e-20 |
67.5 |
In-house |
18-164 (178) |
alignment |
Range on Protein: 1081-1280
Range on HMM: 18-164/178.0
RAPIHANWVPtpghPHRFIATQSPinatcEDFWAMCMQYEVEHIVMVGRKVEYWkniHNDYLPMWP---Rndlqvgrfmikmtnmdfivqknimrrsfkv
.|.|... |. ..... | .|.... .. . |||.. .|.. .....| ||
sdyinaseil....pglylgslpp.....addlellkelgithivnlteelelg...flkcdpywpeeag..............................
adstgkfaartlTHYQYSQWAERGVPKSHVETYELMEMVK----KSEKPIVVHCSNGIGRSMAFIGTEYLARQveadpTIELTEALKHLHEHRWnGVQTN
.|.. . ||| . ..|..|... ....|..|||| |.||| ... .. .. . | ||.....|.|. .|..
............iqylhipipDhgvpdllehflefvefieealdekggpvlVHCsaGvgRsgtlvaaylmkkl.....glsleeaielvrerRp.ivpnp
SQLYWMT
.||...
gqlrqLy
|
0049772 |
(Phosphotyrosine protein) phosphatases II |
1034-1279 |
4.9e-20 |
67.9 |
In-house |
24-272 (314) |
alignment |
Range on Protein: 1034-1279
Range on HMM: 24-272/314.0
TIENVNVTTIDKDHITESYAYLPEDKHRYPTVPCKPsTAVEVivD-----GkRAPIHANWVPTPghpHRFIATQSPINATCEDF----------WAMC--
.. ... ... . .|. .. .| || ||. ... . . | . . | . |.|..| .. .||||| | . |..|| | |
vlnrrslsvlpeltilvadlflnrdknryldilpad.nrvil..pglpvsg.sdyinasyvdgf...lkfIatqgpleitvvdfreepvlyyngwrmvlr
MQYEVEHIVM---------------------VGRKVEYWknihndylPMWPRNDLQVGRfmikmtnmdfivqknimrrsfKVADSTgKFAARTLTHYQYS
.. | ||| . .. .... ||. . .. .. .. |. .| .
gdlnvrdivmsrdevladelsrLdaAlgKtpllildgng........neptaadlellk.....................eelydp.elferlgikylri
QWAERGVPkSHVETYELMEMVKK--SEKPIVVHCSNGIGRSMAFIGTEYLARQVeadpTIELTEALKHLHEHRW-----NGVQTNSQLYWM
. ..| . .|..|.... ..|..|||. |.||. |. . || .. . | |||..... | . ... |....
pvpDgsap.lledfdeflefieeadkggpvlvHCkaGkgRtgtfvvaaylmkll....gvsleealedvrlkRpinpnpgfieqleqyefi
|
subfamily_Anemone-PTP-1_pd |
Subfamily Anemone-PTP-1 |
1093-1281 |
5.7e-20 |
66.5 |
In-house |
49-235 (239) |
alignment |
Range on Protein: 1093-1281
Range on HMM: 49-235/239.0
GHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYlpmWPRNDLQVGRFMIKMTNMDfiVQKNIMRRSFkVADSTGKFAARTLTHY
| |. .|||| ..... ||| | | |||. .| |. .| || . . . . . . . | . . |.| | |. | . .|
gspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqy...wpdstskycnlrvtlrkte..vfadyiirtf.vmsqvgqteeryvyqy
QYSQWAERGVPKSHVETYELMEMVKKS----EKPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQLYWMTL
... | ..|||. | . | .| |.||| |.||. ||. . . || . . |... . .| ..| | |||. | .. |
hftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlrqakkqktvdifnyvkairedrphmvqtseqyvfihl
|
subfamily_Nvec-PTP-1_pd |
Subfamily Nvec-PTP-1 |
1093-1281 |
5.7e-20 |
66.5 |
In-house |
48-234 (239) |
alignment |
Range on Protein: 1093-1281
Range on HMM: 48-234/239.0
GHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYlpmWPRNDLQVGRFMIKMTNMDfiVQKNIMRRSFkVADSTGKFAARTLTHY
| |. .|||| ..... ||| | | |||. .| |. .| || . . . . . . . | . . |.| | |. | . .|
gspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqy...wpdstskycnlrvtlrkte..vfadyiirtf.vmsqvgqteeryvyqy
QYSQWAERGVPKSHVETYELMEMVKKS----EKPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQLYWMTL
... | ..|||. | . | .| |.||| |.||. ||. . . || . . |... . .| ..| | |||. | .. |
hftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlrqakkqktvdifnyvkairedrphmvqtseqyvfihl
|
PTPc_DSPc_SM00012 |
|
1189-1276 |
2.6e-19 |
64.7 |
In-house |
2-96 (105) |
alignment |
Range on Protein: 1189-1276
Range on HMM: 2-96/105.0
LTHYQYSQWAERGVPKSHVETYELMEMVKKSEK------PIVVHCSNGIGRSMAFIGTEYLARQVEAD-PTIELTEALKHLHEHRWNGVQTNSQL
..||.|..| . |||.. . ||.. |||... |.|||||.|.||. |. ..| .|.|. .... . .|.| ..| . |||. |
vkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqy
|
subfamily_hpo-7_pd |
Subfamily hpo-7 |
1107-1276 |
3.3e-19 |
63.8 |
In-house |
45-216 (263) |
alignment |
Range on Protein: 1107-1276
Range on HMM: 45-216/263.0
ATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDLQVGRFMIKMTNMDFivqkNIMRRSFKVADSTG-KFAARTLTHYQYSQWAERGVPKS
| . |. . | . | .||.. | .. . |.|. . ... . |.. ... .. .. | | .|..||.| | |. |.
qtidkfyqtivqtktevvvmLcDfneegvekcssyfPlekdekqklanvnvcttkvqs....dvllktlellstlgeKkkthtvkhysykgWiekndpel
HVETYELMEMVKKSeKPIVVHCSNGIGRSMAFIGTEYLAR----QVEADPTIEL--TEALKHLHEHRWNGVQTNSQL
| .........| |..|||||.||||| || .| . . ... .|.|| . |..| ..| ..| ||
areilnilkvarns.kslvvhcstGiGrsaafsvaElvyqkmirsldttstveldylsLleelrssrkraihtPmqL
|
subfamily_PTPRN_pd |
Subfamily PTPRN |
1097-1277 |
7.7e-19 |
62.5 |
In-house |
101-282 (297) |
alignment |
Range on Protein: 1097-1277
Range on HMM: 101-282/297.0
RFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYlpmWPRNDLQVGR-FMIKMTnMDFIVQKNIMRRSFKVADSTGKfAARTLTHYQYS
.||||.|...| ||| | . | ||.. | | . . | || . .| . ... . | .. . ||| . . . .||.| . .
ayiatqgplastvadfwqmvweqGvvvivnltrleeegvkqckry...wpdeGsevyhiyevhlv.sehiwcddylvrsfylknlqts.etrtvtqfhfl
QWAERGVPKSHVETYELMEMVKKSE----KPIVVHCSNGIGRSMAFIGTEYL-ARQVEADPTIELTEALKHLHEHRWNGVQTNSQLY
| |.||| | |. | || |||||||.| ||. ..| . . .| . |... .|.|| . | . |.|..|.
swpeegvPasaksllefrrkvnksyrGrscpivvhcsdGaGrtGvyilidlvlnrllkGvkeidiaatlehlrdqrpglvktkdqfe
|
subfamily_egg_pd |
Subfamily egg |
1042-1252 |
8.4e-19 |
62.4 |
In-house |
26-233 (307) |
alignment |
Range on Protein: 1042-1252
Range on HMM: 26-233/307.0
TIDKDHITESYAYLPEDKHRYPTVPCKPSTAVEVIV-DGKR--APIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYwkNIH
..|. .|.... .| | . |.|| |. |.. . |. |||| | || .|.|. | .||| | .| ||..|||. ..| .
svdeislttaasdnnlekarskrvhckdssrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvddfwrmvfqeevqyivmltsrkes..erc
NDYlpmWPRNDLQVGRF---MIKMTNMDFIVQKNIMRRSFKVADSTGKFAARTLTHYQYsQWAERGvpKSHVeTYELMEMVKKSEKPIVVHCSNGIGRSM
. | ||. . . .. ....|.. . . . | |. |. | | |.|. .. . . . . .... .... ||.||.. .|. ..
eyy...wpkaesdslvtvpGslrienlkvdskadplfrvtklklvGgddeerflehwqg.dvnnss..dvys.plrvlrklrnlskpvvvqdilGvskaa
AFIGTEYLARQVEADPT
... | .. |.
tlvaieiallsllrGpi
|
subfamily_Cele-PTP-14_pd |
Subfamily Cele-PTP-14 |
1058-1279 |
9.3e-18 |
58.8 |
In-house |
54-282 (310) |
alignment |
Range on Protein: 1058-1279
Range on HMM: 54-282/310.0
DKHRYPTVPCKPSTAVEVIVDGKRA--PIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYlpmWPRNDLQVGRF
| || | |. .. | . .| | ||||.| | || .| |.. | ||| | .| | |... . .| . | || .
hknrysdvvcldtsrvklkidksryedyihanyvktnylrstficsqgplqhtiidfwrmifqeraesilllckvgeegrpkcvgy...wpslgvtetyg
MIKMTNMDFIVQK--------NIMRRSFKVADSTGKFAARTLTHYQYSQWAERGVPKSHVETYELMEMVKKSEKPIVVHCSNGIGRSMAFIGTEYLARQV
|..||. .. .. | . .. .. .. .| .|||| .. | . . | ||||| |..| . . .. ..
cirvtnlsesseefeicnlavtfvpdnvpvdeqpanlkelrvslikwpnwpdrgvpdekchtvpqrllaqvrhgpcvvhcsagkdrlyvvvalklkidkl
EADPTIELTEALKHLHEHRWNGVQTNSQLYWM
. ... | .|. .| .||. | ..
drglkvdaeevktellksraiciqtelqylii
|
subfamily_Sponge-PTP1_pd |
Subfamily Sponge-PTP1 |
1035-1276 |
5.3e-17 |
56.7 |
In-house |
12-248 (267) |
alignment |
Range on Protein: 1035-1276
Range on HMM: 12-248/267.0
IENVNVTTIDKDHITESYAYLPEDKHRYPTVpcKPSTAVEVIVDGKRAP-IHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKveY
|... . .. |. |.| ....|. . | ||. | | | .| . . ||.|| |.. | ||. . ....| ||.. . .
felikkisdtsstisqsiaeknqernrlddn..lpyddtrvilrtkeeeyinasyvegyktknafivtqdplkntitdfltvihdqkvpvivlltkv..f
WKNIHNDYLPM----WPRNDLQVGRFMIKMTNMDFIVQKNImrrSFKvaDStgkfAARTLTHYQYSQWAERGVPKSHVETYE-L--MEMVKKSEKPIVVH
||. . | .|| | . . | | |. .. || . .|. .| | | .| | ... . . ... ..|.||.
tdnirlfwPPkmgqakkyqdltvehslekeendyqiitlel...kfk..ne....sahnvtlyyykkwnintnnkpylkplfgilaknqlengnrPlvva
CSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQL
||.|.||| .|. . ... . . .. . |... . | |.| .
csdGvGrsGtflvidsqleraktegvsdifdflrkirsqriglvdtkery
|
subfamily_Cele-PTP-7_pd |
Subfamily Cele-PTP-7 |
1103-1283 |
2.4e-16 |
54.1 |
In-house |
98-284 (302) |
alignment |
Range on Protein: 1103-1283
Range on HMM: 98-284/302.0
SPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDLQVGRFMIKMTNMDFIVQKNIMRRSFKVA------DSTGKFAARTLTHYQYSQ
| . |.| .||. ||.| .| . || .. .| .. |. ||. .| ... ... ..|||. . . | .|. ..|
vpkkstlekhwalieqynvaivvqlcsfvedeekkcaeyysdkvggelkfgrytvktvsvktdleeftdkksfklytveiknekkkkkvkktvdilafsa
WAERGVPKSHVETYELMEMVKKSEKPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQLYWMTLGT
| . | || . ... . | ..||||.|.||. ... | . . .| . .. . . |. ||...|| .. |
wpdhGapkeaytaldilkfcesykknvlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqdeqqliylllcv
|
0048076 |
(Phosphotyrosine protein) phosphatases II |
1161-1280 |
3.7e-16 |
54.6 |
In-house |
21-136 (145) |
alignment |
Range on Protein: 1161-1280
Range on HMM: 21-136/145.0
NMDFIVQKNIMR-RSFkvaDSTGKFAARTLTHYQYSQWAERGVPKSHVETYELMEMV---KKSEKPIVVHCSNGIGRSMAFIGTeYLARQveadPTIELT
..... . .| . .. |. .. |. ..|.| | .||| .. .|..|.. |...|..|||| |.||. .... || .. . |
dlellkdlgittvlnl...tselellerlgiqylylpwpDhgvpdllellleflefieealkeggpvlVHCsaGvgRtgtlvaa.ylmll....lgvsle
EALKHLHEHRWNGVQTNSQLYWMT
|||......|...|.. .||...
ealelvrsqrpgavpnpgqlrfly
|
subfamily_Nvec-PTP-3_pd |
Subfamily Nvec-PTP-3 |
1096-1266 |
4.5e-16 |
53.6 |
In-house |
4-182 (198) |
alignment |
Range on Protein: 1096-1266
Range on HMM: 4-182/198.0
HRFIATQSPINATCEDFWAMCMQYEVEHIVMVGrkvEYWKNIHNDYLPMWPRNDLQVGRFMIKMTNMDFIVQKNI--MRRSFKVADSTGKFAARTLTHYQ
.|.|||| |. | ||| | . ||||| . || || .|| . .|.. |. | . . ..| ..| ..|||
rryiatqhplretladfwqmvwetgsghivmvn...ddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyq
YSQWAERGVPKSHVETY---ELMEMVKKSE----KPIVVHCSNGIGRSMAFIGTEYLARQVEADPT--IELTEALKHLHEHR
.. | |. |. . |. || | |..||||.| | . |. . | | | ..| | | | . |
ftswkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqar
|
subfamily_Anemone-PTP-3_pd |
Subfamily Anemone-PTP-3 |
1096-1266 |
4.9e-16 |
53.5 |
In-house |
5-183 (199) |
alignment |
Range on Protein: 1096-1266
Range on HMM: 5-183/199.0
HRFIATQSPINATCEDFWAMCMQYEVEHIVMVGrkvEYWKNIHNDYLPMWPRNDLQVGRFMIKMTNMDFIVQKNI--MRRSFKVADSTGKFAARTLTHYQ
.|.|||| |. | ||| | . ||||| . || || .|| . .|.. |. | . . ..| ..| ..|||
rryiatqhplretmadfwqmvwetgsghivmvn...ddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyq
YSQWAERGVPKSHVETY---ELMEMVKKSE----KPIVVHCSNGIGRSMAFIGTEYLARQVEADPT--IELTEALKHLHEHR
.. | |. |. . |. || | |..||||.| | . |. . | | | ..| | | | . |
ftswkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqar
|
subfamily_Urchin-PTP-4_pd |
Subfamily Urchin-PTP-4 |
1059-1278 |
5.8e-16 |
52.9 |
In-house |
48-227 (392) |
alignment |
Range on Protein: 1059-1278
Range on HMM: 48-227/392.0
KHRYPTVPCKPSTA--VEVIVDG-KRAPIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWknihndylpmwprndlqvgrf
| || . |. .||| | .. . | ..|. . .||.|.| |. .||| | .| .| |.|| . |
knryknilpydsarvkleviddipdsdylnasyipsfdnekayiasqgpnaaslddfwrmvfqenvttiamvtklkegd.....................
mikmtnmdfivqknimrrsfkvadsTGKfAARTLTHYQYSQWAERGVPKSHVETYELMEMVKKS----EKPIVVHCSNGIGRSMAFIGTEYLARQVEADP
|. ||| . .....| ...||| .... || .|...||| |.||. | . . . .
.........................kgd.dartvaqfhftewPdkdvpkhtssllkfikevkadfGqythpliihcsagvgrtgvvisidsvvahakktr
TIELTEALKHLHEHRWNGVQTNSQLYW
... . . ....| |||. | .
mvdvfnfvtnirrkrpymvqtkeqyaf
|
0048179 |
(Phosphotyrosine protein) phosphatases II |
1177-1279 |
4.7e-15 |
51.1 |
In-house |
37-137 (144) |
alignment |
Range on Protein: 1177-1279
Range on HMM: 37-137/144.0
VADSTGKFAARTLTHYQYSQWAERGVPKSHVETYELMEMVKKS---EKPIVVHCSNGIGRSMAFIGTEYLArqveaDPTIELTEALKHLHEHRWNGVQTN
. . | |. ..|.. | .||| . .|..|.... ..|..|||| |.||. ... . . | |||......|...|..
teeyepefleregiqylhlpwpDhgvpdllellleflefieealeeggpvlVHCsaGvgRtgtlvaaylmk.....klglsleealalvrsrrpgavpnp
SQLYWM
.||...
gqlrfL
|
subfamily_Choan-PTP-4_pd |
Subfamily Choan-PTP-4 |
1079-1204 |
1.4e-12 |
42.1 |
In-house |
57-181 (297) |
alignment |
Range on Protein: 1079-1204
Range on HMM: 57-181/297.0
GKRAPIHANWVPTPG--HPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDLQVGRFMIKMTNMDFI-VQKNIMrRSF
.| | |..| | .. ..| .| |..|| .||| . .. .| |||| . | .. | | . |. | .... .. |. .
terdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrdkcapywpsvvqerlkagdvvveflsstsdefdrvil.tel
KVADStgkFAARTLTHYQYSQWAERGVPK
.. | ..| |. | . |||
qliyr...sesrvvrhvqflswpdhGvps
|
subfamily_ptpA1_pd |
Subfamily ptpA1 |
1084-1241 |
1e-11 |
39.2 |
In-house |
78-250 (418) |
alignment |
Range on Protein: 1084-1241
Range on HMM: 78-250/418.0
IHANWVPTpGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVE--------YWK-NIHNDYLPMWPRNDLQVGRFMIKMTNMDFIVQKNIMRRS
| ||.. .|..||.|| |. | ||| | . . |||. |. | || .| . . .. . .| . ... .. ...|. |
inanyidg.aypkqfictqgplpntiadfwrmvwenrcriivmlsresencrikcdrywpeqiggeqfsiygngnevfgtysvelveviqdpereiitrn
FKVadsTGKFAARTLTHYQYSQWAERGVPKSHVETYELME--------MVKKSE--KPIVVHCSNGIGRSMAFIGTE
.. | . .| .|.||| | .. .| .|. .. |. ||.|||| |.||. .| .
irl...tfegetrditqyqyegwpdhnipdhtqpfrqllhsitnrqnqiipssdrnvpiivhcsagvgrtgtfctav
|
subfamily_Cele-PTP-16_pd |
Subfamily Cele-PTP-16 |
1047-1291 |
9.7e-10 |
32.5 |
In-house |
38-278 (303) |
alignment |
Range on Protein: 1047-1291
Range on HMM: 38-278/303.0
HITESYAYLPEDKHRYPTVPCKPSTAVEViVDgkRAPIHANWVPTPGHpHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKnIHNDYlpMWP
... || |. | | . |.. | . |||... . .. | || |.. |. ||| | .. | .... || | . |. ..|
svsknqfvknmdknrfvdvicldhskvkl.sd..ssyihasyleldss.kkailtqlplshtaadfwqmiieqkvkcvlllltdseydk.lggds..vfp
RND--LQVGRFMIKMTNMdfiVQKNIMRR-SFKV-ADSTGKFAARTLThYQYSQWAERGVPKS-----HVETYELMEMVKKS--EKPIVVHCSNGIGRSM
||. |. .|.. .. . ... ..|| . | |.. . ..| .| .| . ..| ...| .| | | ||.
rnqdflkfeersirvgef...krvelgdgwvlkvlsvsngdyksflhv.hhykawphnsipsdgspkfvkqiwqlqsvlrkysdstptvymslsgcgrag
AF--IGTEYLARQVEaDPTIELTEALKHLHEHRWNGVQTNSQLYWmtlgtMYRLIKEY
.| . | .|. . | .....| |. . . | || ||. .| |. |.
tfalfetahlslhse.qasldlvkclenvrngrlhavqnlsqfsv.....vytllaeh
|
subfamily_Urchin-PTP-2_pd |
Subfamily Urchin-PTP-2 |
1184-1280 |
3e-09 |
30.7 |
In-house |
86-187 (440) |
alignment |
Range on Protein: 1184-1280
Range on HMM: 86-187/440.0
FAARTLTHYQYSQWAERGVPKSHVETYELMEMVKKS-----EKPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQLYW
.||| .|.| | ..|||| .... |..| . |..|||| | ||. | . . |... |.. .. ... | . ||| | .
iesrtlkqyhyqgwpdkgvpkfagpvlkmiqdvnesqekagngpllvhcsagagrtgviiavdsilreakrsdqidifsfinsmrnnrpqmvqtpeqyaf
MT
.
vh
|
subfamily_Fungi-PTP1_pd |
Subfamily Fungi-PTP1 |
1096-1162 |
3.9e-09 |
30.7 |
In-house |
104-165 (350) |
alignment |
Range on Protein: 1096-1162
Range on HMM: 104-165/350.0
HRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYlpmWPRndLQVGRFMIKMTNM
...||||.|. | .||. .... .|. |... .||. . . | |.. ... . .|....
fkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcyrY...Wqe..gsydditvklask
|
subfamily_CG42327_pd |
Subfamily CG42327 |
1060-1208 |
2.2e-08 |
28.1 |
In-house |
32-182 (319) |
alignment |
Range on Protein: 1060-1208
Range on HMM: 32-182/319.0
HRYPT-VPCKPST--AVEVIVDGKRAPIHANWVPTPGHP-HRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDLQVGRF
|. || .. .. | | ..|..| . .||.| . . . ||| . . || . | . .||| | .
srvinvvPlPetrvvlqrigdddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlselGikvcaeylPtketldntslyG
MIKMTNMDFIVQKNiMRRSFKVADSTGKFAARTLTHYQYsQWAERGVPKSHVE
|..| . |... | . | .| |||| | .| | .|| ..
dilvtlkgrevkdr.yaistlllkrvdkeesrelthywy.kwleaevPaeeaa
|
subfamily_eak_pd |
Subfamily eak |
1096-1231 |
2.2e-08 |
27.9 |
In-house |
93-222 (332) |
alignment |
Range on Protein: 1096-1231
Range on HMM: 93-222/332.0
HRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDLQVGRFMIkmTNMDFIVQKNIMRRSFKVadSTGKFAaRTLTHYQYS
...| | . . || | .. ||.. .|| . .. |.| |. |. | . . . .|. .... | ... | | . . ||..
rkyiltGiasedkvfafwqmvleqkspaivqlledvelkleksdkyfpdktreelkfGildv..erkefvkrniletrllel..skGnet.hrvlhykvf
QWAERGVPKSHvETYELMEMVKKSEKPIVVHCSNGI
|.| .|| . . | ...|. . .. . .
Gwtettlpkye.dflalrkvmkevGvlllivmksal
|
TMEM154 |
TMEM154 protein family |
811-871 |
2.1e-07 |
22.4 |
Pfam-A |
37-99 (146) |
alignment |
Range on Protein: 811-871
Range on HMM: 37-99/146.0
AAAVGSSTVSTVSDES--SDFpILFVVIP-VVLILVALVIggIVFIWYRKREEKRKE--KEAEEEN
.| |... .. ... .. .| ..|| |||||. ||. .... ..|| ...| .| |.|.
sanvnleegelseksadqael.vlmiiiPsvvLillllvv..vilvikkkrkrrKqeetsedeked
|
PTPc_motif_SM00404 |
|
1191-1274 |
8.8e-07 |
23.9 |
In-house |
51-128 (140) |
alignment |
Range on Protein: 1191-1274
Range on HMM: 51-128/140.0
HYQYSQWAERGVPKSHVETYELMEMVKKSEKPIVVHCSNGIGRSMAFIGTEYLARQveadpTIELTEALKHLHEHRwNGVQTNS
... .. . . | .... .| ..|... ..||| |. || ..| ... .. ..| ||.. ..| | . .. |
qiplddnekdklskyldkvldfienaekkggkvlVHCqaGvSRSatliiaYlmryr.....qlslaeayefvkerR.piispnl
|
subfamily_Sponge-PTP4_pd |
Subfamily Sponge-PTP4 |
1084-1203 |
1.9e-06 |
21.7 |
In-house |
125-237 (244) |
alignment |
Range on Protein: 1084-1203
Range on HMM: 125-237/244.0
IHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRkVEYWKNIHNDYLPM-WPRNDLQVgrfmiKMTNMDfiVQKNIMRRSFKVaDSTG
| | .| | .| || |. | ||| | .. |. .|..| || . | |. | .|. | .|. | ||| ... .|
inasfvgclgrtaeyiltqhpladtsmdfwkmmlerhvnvlvvlgs.veeedeywpdseplewyeeditv.....tltdrd..efknikasnlei.esdm
KFAARTLTHYQYSQWAERGV-P
. . ..|| .| |.| | |
neshqaltmfqisnwpsdgttp
|
subfamily_CG42327_pd |
Subfamily CG42327 |
1217-1278 |
2.2e-06 |
21.6 |
In-house |
244-306 (319) |
alignment |
Range on Protein: 1217-1278
Range on HMM: 244-306/319.0
KKSEKPIVVHCSNGIGRSMAFIGTEYLARQVEAD-PTIELTEALKHLHEHRWNGVQTNSQLYW
..| |.|||||.|.||. | .. |..| .... . . .. . | . |.| | .
resqGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyef
|
DUF1510 |
Protein of unknown function (DUF1510) |
831-943 |
2.5e-06 |
16.3 |
Pfam-A |
15-125 (217) |
alignment |
Range on Protein: 831-943
Range on HMM: 15-125/217.0
ILFVVIPVVLILVALVIGGIVFIWYRKREEKRKEKEAEEENEKLIAERERMRAIKEEEeRVKAEREK-----VKKEEERLKAEEEKVKVEKernkekVKA
.| . | .|..|...| . ... . .......|.|.|..... .| |.. ..|. ....|. |.||.. ..|||| |.|. .
vLniaiaiVvvlivivaaqllvgnskskkasadeeeeeksedeekteeeevkeeekea.akdedkeddsesekkdeeseeeeeeekekkee......ese
EEERLKAEEEKVKIEKEK
|.|. ..|.|. ..|||
edeketeekeesnvekei
|
subfamily_Sponge-PTP-4_pd |
Subfamily Sponge-PTP-4 |
1084-1201 |
2.8e-06 |
21.7 |
In-house |
16-125 (130) |
alignment |
Range on Protein: 1084-1201
Range on HMM: 16-125/130.0
IHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRkVEYWKNIHNDYLPM-WPRNDLQVGrfMIKMTNMdfivqKNIMRRSFKVADSTg
|.|..| |. .. || |. .|. ||| | .. |. .|..| || . | |. | .|. | . . .. ||| ... .
inasfvGllgrtaeylltqhpladtsmdfwkmmleryvnvlvvlgs.veeedeywpdsePlewyeediivt..ltdrdef.....knikasnleiesdl.
KFAARTLTHYQYSQWAERG
. . ..|| .| |.| |
neshqaltmfqisnwpsdg
|
DUF3377 |
Domain of unknown function (DUF3377) |
818-857 |
5.6e-06 |
16.1 |
Pfam-A |
18-57 (74) |
alignment |
Range on Protein: 818-857
Range on HMM: 18-57/74.0
TVSTVSDESSDFPILFVVIPVVLILVALVIGGIVFIWYRK
.| .|.|.|. .. ||||.|| | ||. .. ||
ivvevddvsgtvnavaVviPlvLalCiLvlvytivqfkrk
|
MFS_1 |
Major Facilitator Superfamily |
805-877 |
5.8e-06 |
11.5 |
Pfam-A |
127-189 (352) |
alignment |
Range on Protein: 805-877
Range on HMM: 127-189/352.0
GTGTGAAAAVGSSTVSTVSdESSDFPILFVVIPVVLILVALviggiVFIWYRKREEKRKEKEAEEENEkliaE
..|....|..| . .. .| .. .|... .|..|.|. .|... .|..........| |
sagfslGailgpllgglla.sslgWravfyilaivsllaav.....lfllllpeepperkrkspkeee....g
|
DUF2763 |
Protein of unknown function (DUF2763) |
742-811 |
6.7e-06 |
13.0 |
Pfam-A |
19-86 (91) |
alignment |
Range on Protein: 742-811
Range on HMM: 19-86/91.0
QNVPSAFQSFDNFLQLFFASQQTISVPPPNPQSNSGGVNTGGTGNGNGSGGpsGDTGTGPTGSGTGTGAA
. . | .. .|..||| . . | .. ...| . . ... |.| .| | . |. | | | |
siivdfflgilefislFFrtllspevekarrknssskkkiddgrGgpgapg..Ggrrlgrigggggpsap
|