Synonym: CELE_Y48G9A.9, Y48G9A.9
Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 44-353 | 5.4e-210 | 690.2 | In-house | 1-310 (310) | alignment | ||
Range on Protein: 44-353
Range on HMM: 1-310/310.0
KKTDDHHRKYVETLNNFIIATEKLGIEGLAKQYRKLDAQQDSSLTFEAFKQNMHKNRYSDVVCRDTTRVKLTIDKSRYEDYIHANYVKTNYLRNTFICTQ
|||||||.||...|.||||||||||||||.||||||||.||||||.||.|..|||||||||||.||.||||.|||||||||||||||||||||.||||.|
kktddhhlkylkalenfiiateklgieglvkqyrkldakqdssltyeaykkymhknrysdvvcldtsrvklkidksryedyihanyvktnylrstficsq
GPLQHTIIDFWRMIFQERAESILMLCKTMEEGRPKCVGYWPSLGVTETYGCIRVTNMGESSDEFEICNLAVTFVPDNVPVDEQPANLKELRVNLIKWPNW
|||||||||||||||||||||||.|||..|||||||||||||||||||||||||||..|||.||||||||||||||||||||||||||||||.|||||||
gplqhtiidfwrmifqeraesilllckvgeegrpkcvgywpslgvtetygcirvtnlsesseefeicnlavtfvpdnvpvdeqpanlkelrvslikwpnw
PDRGVPDEKCHTVPQRLLAQVRHGPCVVHCSAGIGRTGCVVALEFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMIAFARGETDVSEKA
|||||||||||||||||||||||||||||||||..|...||||.....|||||||||.||..|||.|.||.|||||.|||.|.||.|.||||||.|.||.
pdrgvpdekchtvpqrllaqvrhgpcvvhcsagkdrlyvvvalklkidkldrglkvdaeevktellksraiciqtelqyliidrvriifargetevaeki
LAAADAFLKS
|..|||||||
llladaflks
|
|||||||||
0040438 | (Phosphotyrosine protein) phosphatases II | 56-333 | 3.1e-78 | 258.5 | In-house | 4-276 (317) | alignment | ||
Range on Protein: 56-333
Range on HMM: 4-276/317.0
TLNNFIIATEKLGIEGLAKQYRKLDAQQDSSLTFEAFKQNMHKNRYSDVVCRDTTRVKLTIDKSR-YEDYIHANYVKTNYLRNTFICTQGPLQHTIIDFW
|.... |.. .| .....|. .. .. .. ....|..||||.|... | .||||. .... |||.|.||.. .|...||.|||||..|. |||
dlllalldllksdftalleefedllslkldtysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPlpntvedFw
RMIFQERAESILMLCKTMEEGRPKCVGYWPSlGVTETYGCIRVTNMGES-SDEFEICNLAVTFVPDNvpvdeqpanlKELRVNLIKWPNWPDRGVPDekC
||..... ..|.||....| ||.|| |||. | | ||| ..||...| ..... .| |. |. ....|. . ...||| |||.
rmvweqgvtvivmLteleelgrekcaqYwpl.getltygdftvtllseeelagitlrtlevedlgds..........esrtvthfhytgWpdhgvpp..s
HTVPQRLLAQVR------HGPCVVHCSAGIGRTGCVVALEFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMIAFA
.. ...| .|| .||..||||||.||||...|.. ... |... .||.||.. |||.||....||. || ....... .
pdllldfleavrealedpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleyl
|
|||||||||
0050432 | (Phosphotyrosine protein) phosphatases II | 63-333 | 8.1e-77 | 253.9 | In-house | 35-299 (308) | alignment | ||
Range on Protein: 63-333
Range on HMM: 35-299/308.0
ATEKLGIEGLAKQYRKLDAQQD-SSLTFEAFKQNMHKNRYSDVVCRDTTRVKLtidkSRYEDYIHANYVKTN--YLRNTFICTQGPLQHTIIDFWRMIFQ
..|.. .| .....| .... . .. ....|..||||.|... | .|||| . |||.|.||.. .|...||.|||||..|. |||||...
lekaldlglleeefeellsvkplleysvallpenkdkNrykdilpydhsRVkl....degsdYInAsyvdgyssklprkfIatqgPlpntvedFwrmvwe
ERAESILMLCKTMEEGRPKCVGYWPSL--GVTETYGCIRVTNMGESS-DEFEICNLAVTFVPdnvpvdeqpaNLKELRVNLIKWPNWPDRGVPD--EKCH
.. . | ||.|..| ||.|| |||. | ...|| ..||.. | . |.. . .| .|.. . ....|. . ..|||| |||. | .
qnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseevlddytvrtleltnlg..........dgesrtvthfhytnWpdhgvPpspeill
TVPQRLLAQVRHGPCVVHCSAGIGRTGCVVALEFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMIAFA
. ... . ..||.|||||||.||||...||. ... |... .||..|.. ||.||....||. |||...|... ..
dflelvrkslpggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylflyralleyl
|
|||||||||
DSPc_SM00195 | 72-333 | 3.8e-76 | 251.3 | In-house | 2-262 (263) | alignment | |||
Range on Protein: 72-333
Range on HMM: 2-262/263.0
LAKQYRKLDAQQ-DSSLTFEAFKQNMHKNRYSDVVCRDTTRVKLTIDKS-RYEDYIHANYVKTNYLRNTFICTQGPLQHTIIDFWRMIFQERAESILMLC
| ....||.... ... | ...|.|..||||..... | |||||. ... .|||.|||.|.. ....|.|||||..|. |||||...|. . |.||.
lkeefekleestspketteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlt
KTMEEGRPKCVGYWPSL-GVTETYGCIRVTNMGESSDE--FEICNLAVTFVPDnvpvdeqpanLKELRVNLIKWPNWPDRGVPD--EKCHTVPQRLLAQV
. .|.|. || |||. | .||.| |.|... . ... ... .| .|. . .. .|. ... ||||.|||| ... . . . .
eeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegk..........eetrkvtqyqyknWpdhgvpdstksvlellravkksk
R--HGPCVVHCSAGIGRTGCVVALEFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMIAFA
. .||.|||||||.||||..|.......||... |||..||..||||||....||. |||.|........
stssgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi
|
|||||||||
PTPc_SM00194 | 72-333 | 3.8e-76 | 251.3 | In-house | 2-262 (263) | alignment | |||
Range on Protein: 72-333
Range on HMM: 2-262/263.0
LAKQYRKLDAQQ-DSSLTFEAFKQNMHKNRYSDVVCRDTTRVKLTIDKS-RYEDYIHANYVKTNYLRNTFICTQGPLQHTIIDFWRMIFQERAESILMLC
| ....||.... ... | ...|.|..||||..... | |||||. ... .|||.|||.|.. ....|.|||||..|. |||||...|. . |.||.
lkeefekleestspketteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlt
KTMEEGRPKCVGYWPSL-GVTETYGCIRVTNMGESSDE--FEICNLAVTFVPDnvpvdeqpanLKELRVNLIKWPNWPDRGVPD--EKCHTVPQRLLAQV
. .|.|. || |||. | .||.| |.|... . ... ... .| .|. . .. .|. ... ||||.|||| ... . . . .
eeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegk..........eetrkvtqyqyknWpdhgvpdstksvlellravkksk
R--HGPCVVHCSAGIGRTGCVVALEFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMIAFA
. .||.|||||||.||||..|.......||... |||..||..||||||....||. |||.|........
stssgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi
|
|||||||||
0051299 | (Phosphotyrosine protein) phosphatases II | 54-332 | 7.5e-76 | 250.6 | In-house | 7-285 (288) | alignment | ||
Range on Protein: 54-332
Range on HMM: 7-285/288.0
VETLNNFIIATEKLGIEGLAKQYRKLDAQQ-DSSLTFEAFKQNMHKNRYSDVVCRDTTRVKLTIDKS-RYEDYIHANYVKTNYLRNTFICTQGPLQHTII
|| | ... .. . |. ||......| ... | .|.. ....|..||||||... | .||||. .. |||.|.|... .| ..||.|||||..|.
veellklvlkllangltglleefeellsllpdltlsaallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyidgynlkrkfIatqgPlpntve
DFWRMIFQERAESILMLCKTMEEGRPKCVGYWPSlGVTETYGCIRVTNMGESSdefeiCNLAVTFVPDNVPVDEQPANLKELRVNLIKWPNWPDRGVPDE
|||||..... . | ||.|..| || || |||. | ..||| |.||.. | . .. .... ...| . ....|. . ..|||| ||||
dFWrmvweqnvrvIvmltklvelgrekcaqYwpl.ggsltygditvtllseev.....lddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpds
KCHTVPQRLLAQVR----HGPCVVHCSAGIGRTGCVVALEFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMIAF
. . |.. .||.|||||||.||||...||. ... |... .||..|.. ||.|| ...||. ||........ .
pellldflrlvrkalasgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyealley
|
|||||||||
0036941 | (Phosphotyrosine protein) phosphatases II | 76-333 | 9.9e-75 | 246.9 | In-house | 19-277 (297) | alignment | ||
Range on Protein: 76-333
Range on HMM: 19-277/297.0
YRKL-DAQQDSSLTFEAFKQNMHKNRYSDVVCRDTTRVKLtidKSRYEDYIHANYVKTNYLRNTFICTQGPLQHTIIDFWRMIFQERAESILMLCKTMEE
...| . . . ||. ....|..||||.|... | ||||| .. |||.|.||.. .| ..||.|||||..|. |||||..... ..|.||.. .|
feellpllllgslsvallpenleknRykdilpydhtRVkl...ddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqnvtvIvmltelvel
GRPKCVGYWPSL-GVTETYGCIRVTNMGESS---DEFEICNLAVTFVPDNvpvdeqpanlKELRVNLIKWPNWPDRGVPDEKCHTVPQRLLAQV------
||.|| |||. | . ||| ..||...... |.. . .| ||.. .. ....|. . ...||| |||. . . |..
grekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgng..........esrtvthfhytgwpdhgvpespaslldfielvrkvlkllp
RHGPCVVHCSAGIGRTGCVVALEFAYNKLD---RGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMIAFA
..|| .||||||.||.|...|.. ... |. . .||. |.. .||.||....||. ||........ .
sggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallell
|
|||||||||
0046845 | (Phosphotyrosine protein) phosphatases II | 72-333 | 2e-74 | 245.8 | In-house | 2-274 (284) | alignment | ||
Range on Protein: 72-333
Range on HMM: 2-274/284.0
LAKQYRKLDAQQDS---SLTFEAFKQNMHKNRYSDVVCRDTTRVKLTIDKS--RYEDYIHANYVKTN-----YLRNTFICTQGPLQHTIIDFWRMIFQER
| .....| .. . ||.. ....|..||||.|... | .||||. .. |||.|.||.. | ...||.|||||..|. |||||.....
leeefeellsltvklllslsvallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqn
AESILMLCKTMEEGRPKCVGYWPSLGVTETYGCIRVTNMGESS-DEFEICNLAVTFVPDnvpvdeqpaNLKELRVNLIKWPNWPDRGVPD------EKCH
.. | ||....| || || |||. | . ||| ..||.. | | . . .| .|.. . ....|. . ...|||.|||. | ..
vrvIVmltelvengrekcaqYwplegevltygdftvtllseevkddytvrtleltnlgy.........tgesrtvthfhytswpdhgvppspedlleflr
TVPQRLLAQVRHGPCVVHCSAGIGRTGCVVALEFAYNKLDRGL---KVDFEEIITELRKQRAQCIQTEIQYLYIHRVMIAFA
.| . | . ..|| |||||||.||||...||. ... |... .||..|.. ||.|| ...||. ||........ ..
lvrellenlpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleyl
|
|||||||||
0045450 | (Phosphotyrosine protein) phosphatases II | 62-331 | 2.6e-73 | 242.8 | In-house | 19-302 (307) | alignment | ||
Range on Protein: 62-331
Range on HMM: 19-302/307.0
IATEKLGIEGLAKQYRKLDAQQD---SSLTFEAFKQNMHKNRYSDVVCRDTTRVKLTIDKS--RYEDYIHANYV--------KTNYLRNTFICTQGPLQH
. . ...||.|...|| ... . .. ....|..||||.|... | |||||. .. |||.|.|| .. .| ..||.|||||..
llllldfltgllkefekllsvtvfllgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydlkrkfIatqgPlpe
TIIDFWRMIFQERAESILMLCKTMEEGRPKCVGYWPSLGVTETYGCIRVTNMGESS-DEFEICNLAVTFVpdnvpvdeqPANLKELRVNLIKWPNWPDRG
|. |||||..... . |.||....| ||.||. |||. | . ||| ..||...|. |.. . .| || . ....|. . ...||| |
tvedFwrmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdl.........dgtgesrtvthfhytgwpdhg
VPDEKCHTVPQRLLAQV------RHGPCVVHCSAGIGRTGCVVALEFAYNKLDRGLK---VDFEEIITELRKQRAQCIQTEIQYLYIHRVMIA
||. ... ... ..||..||||||.||||...|. .. |... . ||..|.. .||.|| ...|.. || .......
vppsfeelldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyealle
|
|||||||||
0039614 | (Phosphotyrosine protein) phosphatases II | 43-331 | 3.2e-73 | 242.1 | In-house | 5-287 (297) | alignment | ||
Range on Protein: 43-331
Range on HMM: 5-287/297.0
YKKTDDHHRKYVETLNNFIIATEKLGIEGLAKQYRKLDAQQDSsLTFEAFKQNMHKNRYSDVVCRDTTRVKLTIDKS--RYEDYIHANYVKTNYL-RNTF
.... .. .... |. .. . .... .| ... .| .... .. ....|..||||.|... | .||||. .. |||.|.||.. .| ..|
rdallesipiplsvldlllllekansktllllefeellslkpd.ysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkf
ICTQGPLQHTIIDFWRMIFQERAESILMLCKTMEEGRpKCVGYWPSLGVteTYGCIRVTNMGES-SDEFEICNLAVTFvpDNvpvdeqpanlKELRVNLI
|.|||||..|. |||||..... ..|.||.|..| || ||. |||. | ||| ..||.... | . . .| || .. ... |. .
IatqgPlpetvedFwrmvweqgvtvivmLtklvelgr.kcaqywpeegg..tygdftvtllkvehldgytvrtlevtn..ng..........esrtvthf
KWPNWPDRGVPDEKCHTVPQRLLAQV------RHGPCVVHCSAGIGRTGCVVALEFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMIA
...||| |||. . |.. ..||..||||||.||||...|. ... |... .||..|.. |||.|| ...||. || .......
qytgwpdhgvppslellleflelvrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydalle
|
|||||||||
0043336 | (Phosphotyrosine protein) phosphatases II | 55-331 | 6.5e-73 | 240.9 | In-house | 5-275 (278) | alignment | ||
Range on Protein: 55-331
Range on HMM: 5-275/278.0
ETLNNFIIATEKLGIEGLAKQYRKLDAQQDSSLTFEAFKQNMHKNRYSDVVCRDTTRVKLTIDKSRY-EDYIHANYVKTNYLRNTFICTQGPLQHTIIDF
..| .... . . .| ... .|. .. . .. ....|..||||.|... | .||||. ..... |||.|.||.. ..||.|||||..|. ||
kdllkallelllnlktllllefeellsfkldtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpetvedF
WRMIFQERAESILMLCKTMEEGRPKCVGYWPslGVTETYGCIRVTNMGES-SDEFEICNLAVTFVPDNvpvdeqpanlKELRVNLIKWPNWPDRGVPDek
|||..... ..|.||.. .| ||.||. ||| | ..||| ..||...| | . . .| || |. ... |. . ...||| |||.
wrmvwelgvttivmLtelvelgrvkcaqYwp..ggsltygdftvtllkeehlddytvrtlevtnlgdg..........esrtvthyhylgwpdhgvpe..
CHTVPQRLLAQ------VRHGPCVVHCSAGIGRTGCVVALEFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMIA
. ...| . ..|| .||||||.||||...||. ... |.....||.||.. |||.||....||. || .......
slsllldflkavrealedsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyealle
|
|||||||||
0047943 | (Phosphotyrosine protein) phosphatases II | 64-332 | 4.1e-72 | 238.2 | In-house | 6-271 (273) | alignment | ||
Range on Protein: 64-332
Range on HMM: 6-271/273.0
TEKLGIEGLAKQYRKLDAQQD-SSLTFEAFKQNMHKNRYSDVVCRDTTRVKLtidKSRYEDYIHANYVKTNYLRNTFICTQGPLQHTIIDFWRMIFQERA
...||. .|......| ... . .. ....|..||||.|... | .|||| .. |||.|.||.. .| ..||.|||||..|. |||||......
ekllgltllleefelllslkplltysvallpenkdknrykdilpydhsrvkl...gdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvweqnv
ESILMLCKTMEEGRPKCVGYWPSLGV--TETYGCIRVTNMGESS-DEFEICNLAVTFVPdnvpvdeqpaNLKELRVNLIKWPNWPDRGVPDEKCHTVPQR
. | ||....| ||.|| |||. | ..||| ..||...| . | . . .| .|.. . ... |. . ...||| |||. . .
rviVmLtelvelgrekcaqYwpleggelsltygkftvtllseetkddytvrtleltnlg..........tgesrtvthfhytgwpdhgvppslesllefi
LLAQV------RHGPCVVHCSAGIGRTGCVVALEFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMIAF
|.. ..|| |||||||.||||...||. ... | .. .||..|.. ||.|| ..||. ||........ .
elvrkalealpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyealley
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 95-330 | 6.4e-68 | 224.0 | Pfam-A | 1-234 (235) | alignment | ||
Range on Protein: 95-330
Range on HMM: 1-234/235.0
NMHKNRYSDVVCRDTTRVKLTIDKSRyEDYIHANYVKTNYLRNTFICTQGPLQHTIIDFWRMIFQERAESILMLCKTMEEGRPKCVGYWP-SLGVTETYG
|..||||.|... | |||||. .... .|||.|||||. ..||.|||||..|| |||||..||. ..| ||.. .|.|| || ||| . . ..|||
nkkknRykdilpydktrvklkgsegp.sdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesltyg
CIRVTNM-GES--SDEFEICNLAVTFVPDNVpvdeqpanlKELRVNLIKWPNWPDRGVPDEKCHTV--PQRLLAQV--RHGPCVVHCSAGIGRTGCVVAL
|.|... |. ..|. . .| .. .. .. .|. . . ||||.|||... . . ... . ..||.|||||||.||||..|||
dikvelkekekedekeytlrklelkkkkees.........ekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfval
EFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMI
... ..|... .|| .|. ||||||....|.. || .......
dilleqleaeeevdvlqivkelRkqRpgmvqsleqYiflykail
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 95-330 | 6.4e-68 | 224.0 | In-house | 1-234 (235) | alignment | ||
Range on Protein: 95-330
Range on HMM: 1-234/235.0
NMHKNRYSDVVCRDTTRVKLTIDKSRyEDYIHANYVKTNYLRNTFICTQGPLQHTIIDFWRMIFQERAESILMLCKTMEEGRPKCVGYWP-SLGVTETYG
|..||||.|... | |||||. .... .|||.|||||. ..||.|||||..|| |||||..||. ..| ||.. .|.|| || ||| . . ..|||
nkkknRykdilpydktrvklkgsegp.sdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesltyg
CIRVTNM-GES--SDEFEICNLAVTFVPDNVpvdeqpanlKELRVNLIKWPNWPDRGVPDEKCHTV--PQRLLAQV--RHGPCVVHCSAGIGRTGCVVAL
|.|... |. ..|. . .| .. .. .. .|. . . ||||.|||... . . ... . ..||.|||||||.||||..|||
dikvelkekekedekeytlrklelkkkkees.........ekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfval
EFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMI
... ..|... .|| .|. ||||||....|.. || .......
dilleqleaeeevdvlqivkelRkqRpgmvqsleqYiflykail
|
|||||||||
0045098 | (Phosphotyrosine protein) phosphatases II | 77-331 | 8.1e-68 | 224.1 | In-house | 15-270 (278) | alignment | ||
Range on Protein: 77-331
Range on HMM: 15-270/278.0
RKLDAQQDSSLTFEAFKQNMHKNRYSDVVCRDTTRVKltidksryeDYIHANYVKTNylRNTFICTQGPLQHTIIDFWRMIFQERAESILMLCKTMEEGR
..| . |. |. . |..||||.|... | .||| |||.|.|... ...||.|||||..|. |||||..... ..|.||.. .| ||
fllllgipseitpalylgnldknRykdilpydhsrVk.........dYINAsyidgy..pkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgr
PKCVGYWPSlGVTETYGCIRVTNMGESSDefeicNLAVTFVPDNVPVDEQPANLKELRVNLIKWPNWPDRGVPDEKCHTVPQRLLAQV------------
||. |||. | ..||| ..||.. |. . .. . . . ....|... |. .....||| |||.. .. ..|| ..
ekcaqywpe.ggsltygdftvtllseevl.....ddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslll
-------RHGPCVVHCSAGIGRTGCVVALEFAYNKLdrGLKVDFEEIITELRKQRAQ-CIQTEIQYLYIHRVMIA
..||..||||||.||||..||. . | . .||..|...|||.|| . ..|.. || .......
sslllldsggpvlVHCsaGvgRtGtlvaaylmlell..eggvdlleavkelrsqRpglavqnleqyrflyeflle
|
|||||||||
subfamily_PTPRD_pd | Subfamily PTPRD | 55-353 | 1.1e-67 | 224.0 | In-house | 8-302 (564) | alignment | ||
Range on Protein: 55-353
Range on HMM: 8-302/564.0
ETLNNFIIATEKLGIEGLAKQYRKLDAQQDSSLTFEAFKQNMHKNRYSDVVCRDTTRVKL-TIDKSRYEDYIHANYVKTNYLRNTFICTQGPLQHTIIDF
..|.... .. . . ..|.|.. .| .. . . ..| .||||...| |..||.| .... ||| |..... |...| |||||..|| ||
aelkehvaklkansdlkfeeeykkieegqqftweaankpaNkaKNRyanivaYdhsRVvLskvegdegsDYINAsfidgyrkrkayIAtqgPlaetiedF
WRMIFQERAESILMLCKTMEEGRPKCVGYWPSLGvTETYGCIRVTNMGE-SSDEFEICNLAVtFVPDnvpvdeqpaNLKELRVNLIKWPNWPDRGVPDEK
|||..... ..| || |. |.|. || |||. | ||||| . || . | ..||... . . . . |. .. .|||.|||..
WRmvweqnsstiVmltkleEkgkvkchkYWPekg.tetygeltVtleeeeeladyeirtfkl.kkkk.........ssesreVrqFhFtsWPdhgvpesa
CHTVP----QRLLAQVRHGPCVVHCSAGIGRTGCVVALEFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMI-AFARGETDVSEKALAAA
.. . | |.. .|| |||||||.||||. .... ... .|| .....||||| .||| || .||... | | |.|.|. ..| ..
tslLdlirkvralnepdagPivVhCSaGVGRTGtfividamlerikeektvDiyqyvkalrkqRnamVqteeQYiFiheailealacgntevesenlkqh
DAFLKS
|..
lqkLae
|
|||||||||
0040439 | (Phosphotyrosine protein) phosphatases II | 88-330 | 1.6e-67 | 223.0 | In-house | 4-243 (249) | alignment | ||
Range on Protein: 88-330
Range on HMM: 4-243/249.0
TFEAFKQNMHKNRYSDVVCRDTTRVKLTIDKSRY-EDYIHANYVKTNYLRNTFICTQGPLQHTIIDFWRMIFQERAESILMLCKTMEEGRPKCVGYWPSl
.. .. |..||||.|... | .||||.| .... |||.|.|... | ..||.|||||..|. |||||..... ..|.||....| || || |||.
svallpenkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywpl.
GVTETYGCIRVTNMGESS-DEFEICNLAVTFVpdnvpvdeqpANLKELRVNLIKWPNWPDRGVPDEKCHTVPQRLLAQV------RHGPCVVHCSAGIGR
| . .|| ..||.. . . |.. . .| .|.. . ....|. | ...||| |||. ... ... ..||..||||||.||
ggsleygdftvtllsvevkddytvrtleltnl..........ydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgR
TGCVVALEFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMI
||...|. ... |.. |.||.||.. .||.|| ...|.. || .......
tGtfiaaylmleqlekelgvdleeavkllrsqRpgavqnpeqyrflyeall
|
|||||||||
subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 60-332 | 2.1e-66 | 219.0 | In-house | 6-276 (307) | alignment | ||
Range on Protein: 60-332
Range on HMM: 6-276/307.0
FIIATEKLGIEGLAKQYRKLDAQQDSSLTFEAFKQNMHKNRYSDVVCRDTTRVKLTIDKSrYEDYIHANYVKTNYLRNTFICTQGPLQHTIIDFWRMIFQ
.. | . |.. | ..|.| .. ..| |||. | .||||.|| |.| .|. ...| |||||||. . . |||.||||. |. .|| |. |
wvqrtldkgvqalvdefrvlakktpegvtveafsantdknryqdvkcqdkgrivvkfdgl.asdyihanylgiaikpkkficaqgplentqysfwamaiq
ERAESILMLCKTMEEGRPKCVGYWPSL-GVTETYgcirvtnmGESSDEFEICNLAV-TFVPDNVPVD----EQPANLKELRVNLIKWPNWPDRGVPDEKC
|. ||..||||..| .. || ||| | . .. ||... . || . .. ||. .. . | .. ..| ||||||||. .
ekvesvimlckvielakikceqywpleegqklvf........geapntisvanlgakklapdedlinvttlkvdwaqksrtiqhlqwenwpdrgvpqinl
HTVPQRLLAQVRHGPCVVHCSAGIGRTGCVVALEFAYNKLDRGLK-VDFEEIITELRKQRAQCIQTEIQYLYIHRVMIAF
.. . . | |||||||.||.| .||. . .|. .| | .... |||.|| .||||.||||.|||.. .
tainlleavrydtnpvvvhcsaGvGrsGtivaislvqdkmiaGinckdmkklveelrsqrhyaiqteaqylylhrvlley
|
|||||||||
0042113 | (Phosphotyrosine protein) phosphatases II | 89-330 | 5e-66 | 217.9 | In-house | 3-240 (245) | alignment | ||
Range on Protein: 89-330
Range on HMM: 3-240/245.0
FEAFKQNMHKNRYSDVVCRDTTRVKLTIDKSRY-EDYIHANYVKTNYLRNTFICTQGPLQHTIIDFWRMIFQERAESILMLCKTMEEGRPKCVGYWPSlG
. ... |..||||||... | |||||. |.... |||.|.||.. . ..||.|||||..|. |||||..... ..|.||....| ||.|| |||. |
vallpenkdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywpl.g
VTETYGCIRVTNMGESSdEFEICNLAVTFVPDnvpvdeqpANLKELRVNLIKWPNWPDRGVPD-----EKCHTVPQRLLAQVRHGPCVVHCSAGIGRTGC
. ||| ..||...| . . ... .. ... . ... |. . . .||| |||| .... .. ||. ..||..||||||.||||.
esltygdftvtllseeh.lddytvrtlevtnl........gddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGt
VVALEFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMI
..|. ... |.. |.|..||.. |||.|| ...||. || .......
fiaaylmleqlekelgvsleeavkelrsqRpgavqtpsqyrflyeall
|
|||||||||
subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 60-350 | 1.4e-63 | 209.4 | In-house | 12-304 (305) | alignment | ||
Range on Protein: 60-350
Range on HMM: 12-304/305.0
FIIATEKLGIEGLAKQYRKLDAQQDSSlTFEAFK--QNMHKNRYSDVVCRDTTRVKLtiDKSRYEDYIHANYVKTNYLRNTFICTQGPLQHTIIDFWRMI
|. | . | .|| ... . .| ..||| |. .|||| || | | |||| . . .||||||| | . ||||| ||..| ||| |
fvkrtlekgpaglraefvamkrfndfe.kmkafkeaqeagknrykdvgcldnnrvkl..egpwpheyihanyvstptnpkrfictqaplektcadfwymc
FQERAESILMLCKTMEEGRPKCVGYWPSLGVTE---TYGCIRVTNMGESSDEFEICNLAVTFVPDNVPVDEQPANlKELRVNLIKWPNWPDRGVPDEKCH
.|.. |.|.|||. .| | ||. |..| . . ... ||| .... . | . | . | | | | . | ..|. .| .|||||||
lqdkveaifmlcnllekgakkcleyfaskdkdvlefeekgqkisvkfessvtlkfrkdakakvtetvlviegpge.karkvthyhwidwpdrgvpaadla
TVPQRLLAQVRHGPCVVHCSAGIGRTGCVVALEFAYNKLDRGLKVD-FEEIITELRKQRAQCIQTEIQYLYIHRVMIAFARGETDVSEKALAAADAF
. |.. .|| |||||||||||| || ||. ..| | ... . |. .|.|| . |||. |||..|.|.. . | . . |. .| .||
ilellekarpskgpivvhcsagigrtgsvvmleyildqllagqiiedtdkilqkireqrnnsiqtdaqylfvhqvilnyfrkkklldeevkeaykaf
|
|||||||||
subfamily_PTPRB_pd | Subfamily PTPRB | 70-336 | 8.1e-63 | 207.2 | In-house | 25-288 (293) | alignment | ||
Range on Protein: 70-336
Range on HMM: 25-288/293.0
EGLAKQYRKLDAQ-QDSSLTFEAFKQNMHKNRYSDVVCRDTTRVKL-TIDKSRYEDYIHANYVKTNYLRNTFICTQGPLQHTIIDFWRMIFQERAESILM
.....| .| | .| . .. ..| ||||.... |..|||| ...... .||| |||.. . .. || ||||| .|. |||||....... |.|
lrfseeyeelkavgkdqavkaaelavnraknrytnilpydhsrvkLaalkdesgsDYinanyipgynsprefiatqGPlpetvddfWrmvwekkssiivm
LCKTMEEGRPKCVGYWPSLGVTETYGCIRVTNMGES-SDEFEICNLAVTFvpdnvpvdeqpaNLKELRVNLIKWPNWPDRGVPDEKC------HTVPQRL
| ...|.|. || |||. . .|| |.|| . |. ... | .|... . .| .|. .. ||| |||.. .|| ...
ltqlvekgkvkCeeYWPadeepvlyGdikvtlvaeeeledwvirelkiek............ekeerkvrqyhftsWpdhgvPektktlldfvrtvreai
LAQVRHGPCVVHCSAGIGRTGCVVALEFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMIAFARGE
. ...| |||||||.|||| .||. ..... || |..|||..|.. .||| ||..||...... | .
ektaskrPivvhCsaGvGRtGtfialdrllqaieeedyvdifgivaelReeRnllvqtekqYifihqcvldllrkk
|
|||||||||
subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 58-333 | 2.1e-60 | 198.9 | In-house | 12-289 (305) | alignment | ||
Range on Protein: 58-333
Range on HMM: 12-289/305.0
NNFIIATEKLGIEGLAKQYRKLDAQQDSSLTFEAFKQ------NMHKNRYSDVVCRDTTRVKLtiDKSRYEDYIHANYVKTNYLRN-TFICTQGPLQHTI
..|.. . .|.. | ...|.| .| ||. .. ||||.|| |.| . ||| || |||||||| . . |||.||||..||
eqfvlraldvgvdklreefrglakytrpdmtqvafnanqsadiaitknryqdvpcqdqsavkl..dkpspsdyihanyvgcpmipekrficaqgpldqti
IDFWRMIFQERAESILMLCKTMEEGRPKCVGYWPSL-GVT-ETYGCIRVTNMGESSDEFEICNLAVTFVpdNVPV-DEqpanlKELRVNLIKWPNWPDRG
.|| |. |.. | |.|||||.| |. || ||| | | . | | |. | .. .| . |. . ... | ..| .|||||
defwwmviqnkveqivmlcktvelgklkcaqywpaaqgeklelksgivvenvsgskpmerdaeiqitll..nltysgd.....qkmsvrhlqwtewpdrg
VPDekCHTVPQRLLAQVRH--GPCVVHCSAGIGRTGCVVALEFAYNKLDRGLKV-DFEEIITELRKQRAQCIQTEIQYLYIHRVMIAFA
|| |. ||. .| | |||||||||||| .||.|. .|. .. . |.. || ||| ||...|||.|||||. .
vpp..ckltslellsairgskvpivvhcsagigrtgtivaieyilekiaenkpcppmpelvkalrdqrafsiqndvqylfihrvmlnyf
|
|||||||||
subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 62-335 | 1.7e-58 | 193.0 | In-house | 13-283 (288) | alignment | ||
Range on Protein: 62-335
Range on HMM: 13-283/288.0
IATEKLGIEGLAKQYRKL-DAQQDSSLTFEAFKQNMHKNRYSDVVCRDTTRVKLTI-DKSRYEDYIHANYVKTNYLRNTFICTQGPLQHTIIDFWRMIFQ
. ... . .|. ..|..| ....| | .| .|||| ... | .||||. .. . .||| |.|.. . ....|.|||||..|. |||.....
akksarnrtgfseeynsLaalektksvtagrlavnakknRyrnilpyDekrvklkkleeeagaDYinasyidgekkkkkyiatqgPladtvndfWelvye
ERAESILMLCKTMEEGRPKCVGYWPSLGVTETYGCIRVTNMGESSDEfEICNLAVTFVpdnvpvdeqpANLKELRVNLIKWPNWPDRGVPDEKCHTVPQR
.... |.|| . .|.|. || |||. . . || . || ... | .. . . . . .||... .. ||| |||. | . .
nktstivmltelveggktkCeeYWPdadkpknyGsvtvtlveskele.dfvlrkllle..........kkkteleitqyqylaWpdhgvPeskapllell
LLAQVR----HGPCVVHCSAGIGRTGCVVALEFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMIAFA--RG
.| || .||||||.|||| .||. . ..... ..| .....||||||. .||. || .|..|.. . .|
rqvkvanqadtgpiivhCsaGvGrtgtFialdalidaveeedyiDvagtvaklRkqRallvqtlkqYefiyevllslieedg
|
|||||||||
0037934 | (Phosphotyrosine protein) phosphatases II | 91-330 | 2e-58 | 193.2 | In-house | 6-239 (243) | alignment | ||
Range on Protein: 91-330
Range on HMM: 6-239/243.0
AFKQNMHKNRYSDVVCRDTTRVKLtidKSryEDYIHANYVKTNylrNTFICTQGPLQHTIID----FWRMIFQERAESILMLCKTMEEGRPKCVGYWPsl
...|..||||||... | .|||| .. .|||.||... ...|.|||||..|. | ||||..... ..|.||....| || ||. |||
llpenlsknrysdilpydhsrvkl...eg..sdyinanliyvt...prliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywp..
GVTeTYGCIRVTNMGESSD-EFEICNLAVTFVP-DNVPvdeqpanlkeLRVNLIKWPNWPDRGVPDE--KCHTVPQR----------LLAQVRHGPCVVH
| . ||| ..||...|.. .. . .| .. .. |... . | . . .||| ||||. . . ||| ..||..||
gev.tygdftvtllseehlddytvrtlllenldlddlt..........rlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVH
CSAGIGRTGCVVALEFAYNKLdrglKVDFEEIITELRKQRAQ-CIQTEIQYLYIHRVMI
||||.||||...|. . .| .||.||.. .||.|| . ..||. || .......
CsaGvgRtGtliaaylmllll....gvdleeavkllreqRpgkavqtpsqyrflyeall
|
|||||||||
subfamily_PTPN6_pd | Subfamily PTPN6 | 54-339 | 4.4e-58 | 191.7 | In-house | 13-303 (306) | alignment | ||
Range on Protein: 54-339
Range on HMM: 13-303/306.0
VETLNNfiiATEKLGIEGLAKQYRKL---DAQQDSSLTFEAFKQNMHKNRYSDVVCRDTTRVKLTIDKSRYEDYIHANYVKTN--YLRNTFICTQGPLQH
|. |.. .|.|. .|. ... .| .|.. | . | ..|..|||| .. | |||.|. .. .||| |||.|.. ....| ||| |..
vselek...eeeslekagfeeefeelqqeeakkllsrkegakpenkeknryknilPfDhtrvilkepsvpgsdyinanyikkevkgsdksyiatqgclet
TIIDFWRMIFQERAESILMLCKTMEEGRPKCVGYWPSLGVTETYGCIRVTNMGESS-DEFEICNLAVTFVpdnvpvdeqPANLKELRVNLIKWPNWPDRG
|. |||||..|| .. |.|. | .| |. ||. |||. .|.|| |.|||. |.| ..... .| |. . . .| .| .. .||| |
tvsdFWrmvwqensrvivmttkevErgkekCarYWPdeeekeeyGkisvtnvseksladYilRelsvskk.........kkkkeerevfqyhfksWPdhg
VPDEKCHT------VPQRLLA--QVRHGPCVVHCSAGIGRTGCVVALEFAYNKLDR-G--LKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMIAFARGE
|| .. . | .. . ..|| |||||||||||| .. .. ... . | ..| .... .|.|| . .||| || ...... .. . .
vpkdpgavLdfledvnrkqeeleeaeagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqteqqykfvykaikkyietk
TDV
...
kkl
|
|||||||||
subfamily_PTPN12_pd | Subfamily PTPN12 | 78-337 | 4.7e-58 | 191.4 | In-house | 23-281 (290) | alignment | ||
Range on Protein: 78-337
Range on HMM: 23-281/290.0
KLDAQQDSSLTFEAFKQNMHKNRYSDVVCRDTTRVKLTIDKSRY-EDYIHANYVKTNYLRNTFICTQGPLQHTIIDFWRMIFQERAESILMLCKTMEEGR
|. |.. | . ..|..|||| |.. |..||.|. ... .||| ||..| . . ..| .|||| .|. ||||||.. . | ..|.|. .| |.
kykaekvysteagekeenvkknrykDilPydksrvelskieeeegsdYinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgk
PKCVGYWPSLGVTET-YGCIRVTNMGESS--DEFEICNLAVTFVpdnvpvdeqpanLKELRVNLIKWPNWPDRGVPDEKCHTVP----QRLLAQVRHGPC
|| |||. | .|. .| ..||.. | |.| | |.|.. .. .|. ... .|||.||| . . . | | . . |
kkCerYWpeegeeelefgefevtleeekavdddflirtLkveaq............kesrkvyqfhYtaWPDhgvPssaksllelielvrelqesedaPl
VVHCSAGIGRTGCVVALEFAYNKLDRGLK---VDFEEIITELRKQRAQCIQTEIQYLYIHRVMIAFARGET
|||||||.|||| ..|...... | .. .| ....||||||| .||. || .... .. . . |
vvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelvqkel
|
|||||||||
subfamily_PTPRG_pd | Subfamily PTPRG | 59-346 | 2.3e-57 | 189.5 | In-house | 8-301 (563) | alignment | ||
Range on Protein: 59-346
Range on HMM: 8-301/563.0
NFIIATEKLGIEGLAKQYRKLDAQQD---SSLTFEAFKQNMHKNRYSDVVCRDTTRVKLTID--KSRYEDYIHANYVKTNYLRNTFICTQGPLQHTIIDF
. ... | |..... .| . .. ..| .||||...| | .||||. | . ||| |||.. . . || |||||..|. ||
khvaslhadgdigfseefealqsetiskdldaehsqkpenkrKnRylnivaydrsRvklsplpgkkkklDYinAnyidGyqkskafiatqgplkdtfddF
WRMIFQERAESILMLCKTMEEGRPKCVGYWPSlGVTETYGCIRVTNMGEssdEFEICNLAVTFVPDNVPVDEQPANLKELRVNLIKWPNWPDRGVPDEKC
||||...... | |. . |.|| || |||. .|||| ..|| . | | .. |.| |. .... .|..| ....||| |||. .
WrmiWeqnvaiivmitnlvergrrkcdvYWPk.desetygalqvtliee...evlalytvrtlviknlklkkkkqcdteklvrqyhytkWPdhgvPehsl
HT---VPQRLLAQVR-HGPCVVHCSAGIGRTGCVVALEFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMIA-FARGETDVSEKALAA
| .. |. . || |||||||.|||| ..|. ... . .|. ... .| || .||| ||...| ... | .||..... . .
pvLifvkkssaankaeaGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvqteEqYiflhdalleaiasketellaeqvee
|
|||||||||
subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 56-346 | 2.9e-57 | 189.1 | In-house | 6-294 (318) | alignment | ||
Range on Protein: 56-346
Range on HMM: 6-294/318.0
TLNNFIIATEKLGIEGLAKQYRKLDAQQDSSLTFEAFKQ-NMHKNRYSDVVCRDTTRVKLTIDKS-RYEDYIHANYVKTNYLRNTFICTQGPLQHTIIDF
|.. . .. | | ..| .|. ..... .... .. | .|||| ... |.|||||. .. ||| |||. . ....| .|.|| .|| ||
dleshvrrlresGelllseeyerlsrseetvtslkslepvnkaknryanilaydhtrvkLqmlegeegsDyinanyidGyrrkkayiaaqaPlpetieDf
WRMIFQERAESILMLCKTMEEGRPKCVGYWPSLGvTETYGCIRVTNMgessDEFEICNLAVTfvpdNVPVDEQPANlKELRVNLIKWPNWPDRGVPDEKC
|||... . |.|| ...|.|. |. |||| | ...|| ..|. . .|.|. .. . .. | .. . .. | .. .|||.|||.. .
WrmvWeqnsavivmltqeeergkakvhryWPskg.srsygklvvelk....eevelsdyvlr....efkvtrteee.esrqvrqyhytsWpdegvpesga
HTVP-----QRLLAQVRHGPCVVHCSAGIGRTGCVVALEFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMIA-FARGETDVSEKALAA
. . .. .. .|| |||||||.|||| .|.. ... || .....||.|| .||| || .|. |.. | |.|.|. . |..
slldlvrqvskaqqksgagpivvhCsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqtedqyefiydvllealasgdtevdasdlrs
|
|||||||||
subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 49-333 | 3e-57 | 188.5 | In-house | 6-283 (290) | alignment | ||
Range on Protein: 49-333
Range on HMM: 6-283/290.0
HHRKYVETLNNFIIATEKLGIEGLAKQYR-KLDAQ-QDSSLTFEAFKQNM--HKNRYSDVVCRDTTRVKLTidKSRYEDYIHANYVKTnyLRNTFICTQG
.| .|....| . | ....|||.| || | . | .| .|||| |||| | ||| | ||.|||||| |. .|| |||
rhsvqteafekfasdvvkknvdelakeyleklkpylpvqylerkifdkntefkknrykdvvcndktrvilk..dGydGdyvhanyvkG..lkamfiltqG
PLQHTIIDFWRMIFQERAESILMLCKTMEEGRPKCVGYWPS-LGVTETYGCIRVTNMGESSDEFEICNLAVTFVpDNvpvdeqpANLKELRVNLIKWPNW
.|. |.||.|||. ||.. | |||. .|.|..|| |.| | . |.| | |. |.... .| .. | . || ... .| |
alkdtvidiwrmvlqekvaaivmlceliedGkakceqyypekeGevltfGeitvlcseeddkdaniikktlsvr.dk.......dsGkehklkhlkiksw
PDRGVPDEKCHTVpqRLLAQVR--HGPCVVHCSAGIGRTGCVVALEFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMIAFA
||. |. . . |.| .| || |||||||||||| ||.| . . | | ..| ... ||. |.. .| .|||| . .... .
pdksvalstlall..rtlrilrkasGpvvvhcsaGiGrtGtfvaievglqilldGkeldlldlvralrnsrlnsvqvdiqylalveilldlG
|
|||||||||
subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 66-330 | 1e-56 | 187.1 | In-house | 11-273 (281) | alignment | ||
Range on Protein: 66-330
Range on HMM: 11-273/281.0
KLGIEGLAKQYRKLDA-QQDSSLTFEAFKQNMHKNRYSDVVCRDTTRVKLT-IDKSRYEDYIHANYVKTNYLRNTFICTQGPLQHTIIDFWRMIFQERAE
. .|....|.|| | ..|.. | ..|..|||||..| | ||||.| ... ||| ||.|.. . .| ||||. ... .||.|.......
qndnaGfieeyeklaaigvdntataskadenvlknrYsnivaYDatrvkvtpneenkntDYinanfvpgykgekeyiatqgPvPaslvafWqmvweqkvs
SILMLCKTMEEGRPKCVGYWPSLGVTETYGCIRVTNMGESSDEfeicnlavTFVPDNVPVdEQpANLKELRVNLIKWPNWPDRGVPDEKCHTVPQRLLA-
| |. . .|.|. || ||| . .|| ..|... |.. . |.. .. . |. . .. .|. ... .||| |||.. . . |
aivmvtreieagklkChrYWPddnselkygdvtvkstaeeeka........tyierkfkl.er.esgetreveqlaytaWPdhGvPattkellefrkevl
--QVR--HGPCVVHCSAGIGRTGCVVALEFAYNKLDRG-LKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMI
. . . | |.|||||.||||. .||. . ..... ..| .....||||.| .|| .|| .......
kltekktkaplvihCsaGvGrtGtyialDrlvkaveaeleeldvkavvaelrkernlmvqtvvqyefvykavl
|
|||||||||
subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 91-334 | 1.9e-56 | 186.2 | In-house | 24-269 (274) | alignment | ||
Range on Protein: 91-334
Range on HMM: 24-269/274.0
AFKQNMHKNRYSDVVCRDTTRVKLTIDKSRYE--DYIHANYVKT-NYLRNTFICTQGPLQHTIIDFWRMIFQERAESILMLCKTMEEGRPKCVGYWPSLG
. .|||| ... ...|| |. ..|. | .|| |||.| .. .... |||||..|. ||||||.||... |.|| | |. . ||. |.|
dvfgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneqkCavyfPdae
---VTETYGCIRVTNMGE-SSDEFEICNLAVTFVPDNVPvdeqpanlkelrVNLIKWPNWPDRGVPDEK------CHTVPQ-RLLAQVRHGPCVVHCSAG
..|.|| . ... . . ..... .| . . .. | . ...|||. .||. .. | . | .. . .| |||||||
dyeiserygdveikvekiverndysvrklvlkylerers............vkhywytdWPdhksPddantlldlvleveesreeenaklapvvvhCsaG
IGRTGCVVALEFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMIAFAR
|||||| .| . | ..|.. .|| .|...|| .| .||. || .|||... ...
iGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralclylk
|
|||||||||
subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 51-332 | 2.5e-56 | 186.1 | In-house | 8-289 (298) | alignment | ||
Range on Protein: 51-332
Range on HMM: 8-289/298.0
RKYVETLNNFIIATEKLGIEGLAKQYRKLDAQQD----SSLTFEAFKQNMHKNRYSDVVCRDTTRVKLTI-DKSRYEDYIHANYVKTNYLRNTFICTQGP
... ..|... ..| .. |.|.....|.. .. . . ..| .||||.|.. | .|| |. |. ||| | .... ||.|| ||.|
edlkaalqklaavkkkkkltgyalefqrlnsvsseieeeekevarkpenkkkNRyadiialdssRvvLekedadeesdYiNAsflhaykgrnafiatqaP
LQHTIIDFWRMIFQERAESILMLCKTMEEGRPKCVGYWPSLGvTETYGCIRVTNMGES-SDEFEICNLAVTfvpdnvpvdEQPANlKELRVNLIKWPNWP
|..|. |||||. .| ...| || .. | .. |. |||. | .|||| |.|. . . ......|.|. .. . || .| ... .||
ltetvedFWrmvteedigtiVmltnleeldktkyhkywPdeg.ketygeitvsllskeefadlivrklkvs.........kkkee.kerevrqlhftsWp
DRGVPDEKCHTVPQRL---LAQVRHG--PCVVHCSAGIGRTGCVVALEFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMIAF
|.||| ... . . | . | | .|.||||.||.| .|.. ... . .|| ... |||.|.. .||| || .|. ... .
dkgvpenatsvldllrkvrasqqqagnkpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavlea
|
|||||||||
subfamily_PTPN3_pd | Subfamily PTPN3 | 75-331 | 3.5e-56 | 185.2 | In-house | 20-273 (280) | alignment | ||
Range on Protein: 75-331
Range on HMM: 20-273/280.0
QYRKLDA-QQDSSLTFEAFKQNMHKNRYSDVVCRDTTRVKLTIDKSryeDYIHANYVKTNY----LRNTFICTQGPLQHTIIDFWRMIFQERAESILMLC
|. .| ... ... .|..|||| |.. |.|||||. .. ||| ||||. . | | .| |||||..| |||.|....... |.||
qfeqlyrkkpglaisaarkpenlsknryrdilpydatrvklkeset...dyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqksslivmlt
KTMEEGRPKCVGYWPSLGVTETYGCIRVTNMGEssdefeicNLAVTFVPDNVPVDEQPANlKELRVNLIKWPNWPDRGVPDEKCHTVP----QRLLAQVR
..|.|| || |||. . . .||...|. | . ..| .. . .. .. .| .. ... .||| ||||.. . . | | ...
tlverGrvkChqyWPetedeleygefsvkceke........detksyvlrelvlkdketk.eerkilqlqylaWpdhgvPddsadflefvervrklrsgk
HGPCVVHCSAGIGRTGCVVALEFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMIA
. | |||||||||||| ...|| | .... .| .|. ..| ||| .||. || .. ...
eePvvvhCsaGigrtGvlilletalalieaaepvypldivrtmrdqramlvqtasqykfvCeailk
|
|||||||||
subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 54-339 | 6.1e-55 | 181.5 | In-house | 6-290 (305) | alignment | ||
Range on Protein: 54-339
Range on HMM: 6-290/305.0
VETLNNFIIATEKLGIEGLAKQYRKLDAQqDSSLTFEAFKQNMHKNRYSDVVCRDTTRVKLTIDKSRY-EDYIHANYVKTNYLRNTFICTQGPLQHTIID
...|...| ... .|| .||..| . ..|. . ..| .|||..... |. |..|| ..| .||| |.||.. ....| .||||..|. |
lddlaayikearvysdkgleaqykslyee.eesidvgkkeankaknrlkeitlldddriiltekeslddsdyinasyvdgykrkkkyivaqgPlkntvad
FWRMIFQERAESILMLCKTMEEGRPKCVGYWPSLG-VTETYGCIRVTNMG-ESSDEFEICNLAVTFVPDnvpvdeqpaNLKELRVNLIKWPNWPDRGVPD
|||.|..|. ..|.||.|..|.|. || ||| .. .| . |. .. .. . .| ... . . .. | . .||| |||.
fWrliveekvstivmltklveggkdkCrqYWpesktekkefgefsvelksektasdyieRklkisiede.........dkesrtvlqyqltdWPdhGvpq
EKCH--TVPQRLLAQVRHG---PCVVHCSAGIGRTGCVVALEFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMIAFAR-GETDV
. .. .|. . ... | .||||||.|||| .|.. | ..| . ||. |.. .||..| . .|| || ..| .. |.|..
fatsllslikrvqkdqkkdkgvpllVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkmvqtldqYvflhdaldelitcgdtsi
|
|||||||||
subfamily_PTPRA_pd | Subfamily PTPRA | 76-342 | 3.3e-54 | 179.0 | In-house | 38-305 (330) | alignment | ||
Range on Protein: 76-342
Range on HMM: 38-305/330.0
YRKLDA-QQDSSLTFEAFKQNMHKNRYSDVVCRDTTRVKLTID-KSRYEDYIHANYVKTNYLRNTFICTQGPLQHTIIDFWRMIFQERAESILMLCKTME
. | | . ...| . ..|..|||. ... | .|| |. . ||| | ... ...|| .|||...|. ||||||.. .. .|.|| . |
fnalPagpiqatlelaskeenkeknrvvnilPydfsrvilsvkeGveesdyinasfidGykekdkfiaaqGPkeetvedfwrmiweqksativmltelke
EGRPKCVGYWPSLGVTeTYGCIRVTN-MGESSDEFEICNLAVTFVPDNVPVDeqpanlKELRVNLIKWPNWPDRGVPDEKCHTVP----QRLLAQVRHGP
. || |||. |. ||| |||. . . .. . .. |. .||. . |. |. ... ||| ||| | . . | |. ||
rkeekcaqywPdeGlv.tyGnirvevedetvlvdytvrkflvqqlpdatrek......ksrlvrqfhftswPdvGvPfepiGmlkllkkvkklnqqsagp
CVVHCSAGIGRTGCVVALEFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMIAF-ARGETDVSEK
|||||||.|||| ..|. ... ||| |.. .||.||.| .||. || .|..|. . |.|..
ivvhcsaGvGrtGtfivldavlervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvlleyylygdteldvs
|
|||||||||
subfamily_Ptp69D_pd | Subfamily Ptp69D | 57-345 | 5.4e-54 | 178.4 | In-house | 9-299 (307) | alignment | ||
Range on Protein: 57-345
Range on HMM: 9-299/307.0
LNNFIIATEKLGIEGLAKQYRKLD-AQQDSSLTFEAFKQNMHKNRYSDVVCRDTTRVKLT-IDKSRYEDYIHANYVKTNYLRNTFICTQGPLQHTIIDFW
|.. . . .. .|||| |.|| . | | .. . | | |||| |.. | |||||. | . . ||| |...|. ...||. |.|.. || |||
leealksrkrdtdfglakeyekLeareidkstkvsekkenalknRyedikafDktRvkLkkingkedsdYinasfikgykekkkfiaaqdPveatigDfW
RMIFQERAESILMLCKTMEEGRPKCVGYWPSLgVTETYGCIRVTNMGE-SSDEFEICNLAVTFVPDNVPVDeqpanLKELRVNLIKWPNWPDRGVPdEKC
||| . . | || . | | || ||| . || | |. . | . ... | .| |. . .... .. .| .. .|.| || | .
RmiaeqevtlivmlsnlteknrkkcakYWpie.devqygdilvklvseekhsdyiiReldvskkkeesgev.....edsrkvvqyhytgWkDskvP.eva
HTVP---QRL--LAQVRHGPCVVHCSAGIGRTGCVVALEFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMIAFAR-GETDVSEKALA
... ... | . ..| ||||||| ||.| .|||. ..| ||| |.. .||.|| .| || ...| .. . |.||.. . |.
rgllklieqvrelyklnrsPivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnllvqsleqYvflyralldyssygdtdedvddle
|
|||||||||
subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 76-334 | 4.5e-53 | 175.0 | In-house | 1-265 (270) | alignment | ||
Range on Protein: 76-334
Range on HMM: 1-265/270.0
YRKLDAQQDSSLTFEAFKQNMHKNRYSDVVCRDTTRVKLT-IDKSRYEDYIHANYVK-TNYLRNTFICTQGPLQHTIIDFWRMIFQERAESILMLCKTME
...|| .. |. .. .. .. . ||| |.. .|||.| ... || ||||. . ....|...|||. |. .|||||..|....|.|. . .|
fkeldkeetsesdlpeaargkklnRyadiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleE
EGRPKCVGYWPSLG---VTETYGCIRVTNMGESSDEFeicnlavtFVPDNVPVDEQPanlKELRVNLIKWPNWPDRGVPDEKC-HTVPQRLL---AQV--
.|| || |||. |. ..| |.|... |. .|. .. .. . |. .| |. . .|||.||| |. . .. || ..|
kgrkkCerYWpaepkekvkledgkikvlalseekeeg........yiltrlrleekg...eerrlvHfwyntWpdhgvpreedsslstdqllkmlravrr
------RHGPCVVHCSAGIGRTGCVVALEFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMIAFAR
. .|..||||||.||||...||..| . |.. ||| .||.||||.| ...|. || ....... .|.
sekeldkaePllvHcsaGvgRtGtlialDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyeflykavveyae
|
|||||||||
subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 54-340 | 6.7e-53 | 174.8 | In-house | 7-291 (319) | alignment | ||
Range on Protein: 54-340
Range on HMM: 7-291/319.0
VETLNNFIIATEKLGIEGLAKQYRKLDAQQDSSLTFEAFKQNMHKNRYSDVVCRDTTRVKLT-IDKSRYEDYIHANYVKTNYLRNTFICTQGPLQHTIID
|. |.. . | .. | .|.|....|. .. ... ..| .||||.... | |||.|. .| . ||| |... . |. || ||.||..|| |
vqeLkerlkalastgetllekefkllkeavndtfdsaskeenkkknryqnilaydrtrvvlseldgvegsdyinasfidgyqerekfiatqaPlentied
FWRMIFQERAESILMLCKTMEEGRPKCVGYWPSLGvTETYGCIRVTNM-GESSDEFEICNLAVTFVPDNVPVdeqpanlkeLRVNLIKWPNWPDRGVPDE
||||...|.. ..||.| |... |. |||. |.|| . || | ....| .| . ..| .| .. .||| .||..
fWrmvWeeessivvmltklveklkvklkkywpeen.feeyGrlivtleeeeeledyiirklklnkkssevet.........RevkhfqyteWpdhdvPek
KCHTVP--QRL---LAQVRHGPCVVHCSAGIGRTGCVVALEFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMIAFAR-GETDVS
. .|. . .|| |||||||.|||| ..|. . ... . .| ... .|| || .|.. || .|. ...... |.|..
atslldllkrirksrektqsgPivvhCsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyealleaveagdteie
|
|||||||||
subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 93-332 | 1e-51 | 170.6 | In-house | 7-241 (250) | alignment | ||
Range on Protein: 93-332
Range on HMM: 7-241/250.0
KQNMHKNRYSDVVCRDTTRVKLTIDK-SRYEDYIHANYVKTNYLRNTFICTQGPLQHTIIDFWRMIFQERAESILMLCKTMEEGRPkCVGYWPSlGVTET
|| .||||.|.. | .|| | .| . ||| | .... |..|| ||||||.|| |||||...| ...|.|| . |... . ||| ..|.
pqnkeknryadiialdssrvvLekekgdkesdyinasflhgyderkafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqywPv.ekaek
YGCIRVTNMgeSSDEFEICNLAVTFVPDNvpvdeqpANLKELRVNLIKWPNWPDRGVPDEKCHTV-----PQRLLAQVRHGPCVVHCSAGIGRTGCVVAL
|| ..|. . |..|| . .. . . .| | ... .|||.|||.. . |. |. .| .|.||||.||.|. .|.
yGdvtvsll..skeefadytkrklklska.......kkaderivrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiai
EFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMIAF
. ..| . .|| ..| |||.| . .... || ....... .
davlerlkkekvvdvfkvikvlrkdrphavesleqyvfvyeiilka
|
|||||||||
subfamily_PTPRK_pd | Subfamily PTPRK | 93-340 | 2.8e-50 | 165.9 | In-house | 41-285 (314) | alignment | ||
Range on Protein: 93-340
Range on HMM: 41-285/314.0
KQNMHKNRYSDVVCRDTTRVKL-TIDKSRYEDYIHANYVKTNYLRNTFICTQGPLQHTIIDFWRMIFQERAESILMLCKTMEEGRPKCVGYWPSLgvTET
..| .|||. |.. | .||.| ||| ||| |... . . || ||||||.|. ||||....|.. ||.|| . .|.|| ||. ||| ||.
denreknrsgdilaydrsrvflitidgdpssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasivmltelvevgrvkClkyWPed..tev
YGCIRVTNMGESSDEfEICNlaVTFVPDNvpvdEQPANLKELRVNLIKWPNWPDRGVPDEKCHTV---PQ-RLLAQVRHGPCVVHCSAGIGRTGCVVALE
|| |.|. . . .. |. . .| . . . . |. ... .||| .|| .. . . . ..|. ||||||| ||||. .|..
ygdikvelvetella.elvv..rifrvek....largqeeirevrqfqflgWpdhdvPvsatgllklvrrvkksqeeeaGrivvhCsaGaGrtGtfiaid
FAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMIA-FARGETDVS
. ..| || ... .||... ..|| || .|. |.. ||| .
ivldmieregvvdvfnavktlrsrkvnmveteeqykfiydvileaclcgetaip
|
|||||||||
subfamily_PTPN13_pd | Subfamily PTPN13 | 75-331 | 2.8e-49 | 162.8 | In-house | 16-267 (273) | alignment | ||
Range on Protein: 75-331
Range on HMM: 16-267/273.0
QYRKLDAQQDSSLTFEA-FKQNMHKNRYSDVVCRDTTRVKLTIDKSryedYIHANYVKTNYLRNTF--ICTQGPLQHTIIDFWRMIFQERAESILMLCKT
....| . . .. |.|..|||| .|. | ||||| . . || |...| . ... | .|||| .|. |||.|... .|| | |. .
efkelrelkpldtcevgkkkenkdknryrnvlPydetrvklgdegg....yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamvtle
MEEGRPKCVGYWPSLGVT--ETYGCIRVTNMGE-SSDEFEICNLAVTfvpdnvpvDEQPANLKElrVNLIKWPNWPDRGVPDEKCHTVPQ-RLLAQV--R
|.|. || |||. .. ..|.... |.| . .|||. | . .. .| | ... .||| ||| . . . . ....
kekgkvkchrywPesknkklkvsnrlevellkvqkldgfvvralavk........dsesgesre..vahlnfvkwPdhgvPssaaellqfvaevrrlqtd
HGPCVVHCSAGIGRTGCVVALEFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMIA
.|| ||||||||||.| ..... . . ..| ..| .||. .||.|| .||. ||........
agPivvhcsaGiGrsGtlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykaile
|
|||||||||
subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 54-331 | 2.3e-48 | 159.5 | In-house | 4-281 (290) | alignment | ||
Range on Protein: 54-331
Range on HMM: 4-281/290.0
VETLNNFIIATEKLGIEGLAKQYRKLDA-QQDSSLTFEAFKQNMHKNRYSDVVCRDTTRVKLTIDKSR---YEDYIHANYVKTNYLRNTFICTQGPLQHT
|. . .|.. .. | || .|. .||. ... . | . ..| ..||....| .| |. | .. ..||.| |.| .. .| ||||...|
vdkfgefvanghakgnegfrnqfkmldsgesehtvtvgltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgykekkqyiatqgpvsnt
IIDFWRMIFQERAESILMLCKTMEEGRPKCVGYWPSLGVTEtYGCIRVTNMGESSDE-FEICNLAVTfvpdnvpvdEQPANLKELRVNLIKWPNWPDRG-
..|||..| ||. |.||.. .|||. || |||. .... || .... . |.. . . . .| |. .. .. .. | . ||.. |
lvdFWkliwqekvtiivmltniieegkvkCqqYWpdsdtka.ygefsikllneetlneyierklevk.........nknsagakqsvtqyqitnwdstgk
VPDEK--CHTVPQRLLAQVRH--GPCVVHCSAGIGRTGCVVALEFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMIA
|.... ... .. | .. .. |||||...||.. .|.. . || .| ... ..| |. . .||. || .|.....
vtnpqtillvieemyktqrkrgntsivvHCSdtvgrsavfcaaattinkcktegvidvfqvlksqRiqkpgsvqtvqqyqgifqivlt
|
|||||||||
0051429 | (Phosphotyrosine protein) phosphatases II | 121-352 | 2.4e-48 | 160.5 | In-house | 3-244 (272) | alignment | ||
Range on Protein: 121-352
Range on HMM: 3-244/272.0
YEDYIHANYVKTNYL---RNTFICTQGPLQHTIIDFWRMiFQERAESILMLCKTMEEGRPKCVGYWP-----------SLGVTETYGCIRVTNMGESSDE
...||.|..|.... ........|||..|. ||||. ... .|..|....| || || ||| . | .||..|||.. |. .
lsgyiNardvggygrvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseelll
FeicnlavtFVPDNVPVDEQPANLKELRVNLIKWPNWPDRGVPDEKCHTVPQRLLAqvrHGPCVVHCSAGIGRTGCVVALEFAYNKLDRGLKVD------
. .. .. . . . . ..| .. . .|||.|||.| .... . ||. .||..||||||..|||.|||| . ... ||
d........yilrellltlllsagearevmhlhytdwpdhgvpqeallellellld...ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltn
--FEEIITELRKQRAQCIQTEIQYLYIHRVMIAFARGETDVSEKALAAADAFLK
||.. |||.||.. .||| |||..........|. ..|.. .|.|| ....
lyleeaveelraqrpgavqteeqylflyeallellrsllsvraeyllaaldaid
|
|||||||||
subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 54-329 | 6e-48 | 158.3 | In-house | 3-267 (288) | alignment | ||
Range on Protein: 54-329
Range on HMM: 3-267/288.0
VETLNNFIIATEKLGIEGLAKQYRKLDaQQDSSLTFEAFKQNMHKNRYSDVVCRDTTRVKLTiDKSRYedYIHANYVKTNYLRNTFICTQGPLQHTIIDF
| .|..| . ..||| |.|| .. | . ..| .| ..|| .. . |.|||||. | . . ||.|| | .. .. .||.| ||. || .
kevinawirlvlqiaveglkkeyrdsp.neasidiidsfianptrdryenlprcditrvkls.ddpdf..yiaanvvssakykrrlicaqaPlngtieel
WRMIFQERAESILMLCKTMEEGRPKCVGYWPSLgVTETYGCIRVTN-MGESSDEFEIcNLAVTFVPDNVPVDEQPanlkelRVNLIKWPNWPDRGVPDEk
|.|.... | |.|||. .| |..| |.|| . |. |. . . .. .. . . |. . . ...|. | . . .|.| |||..
WkmllesdveyivmlcellekGkeksaeyfPsk.lGekarigrlctvvkkkradidk.lvkvsllriskegeekv......ivkilhlleWdddgvPen.
cHTVPQRLLAQVR--HGPCVVHCSAGIGRTGCVVALEFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVM
. | ||| .. . | |||.|||.|||| .. .| . | . ......||..| ..|||| ||||.||..
.ylsplrllevlkslqkPivvhssaGvGrtgtlililialeslrlddflgirsllaklreerfkaiqtemqylyvhrcv
|
|||||||||
subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 83-342 | 5.3e-47 | 155.7 | In-house | 49-301 (319) | alignment | ||
Range on Protein: 83-342
Range on HMM: 49-301/319.0
QDSSLTFEAFKQNMHKNRYSDVVCRDTTRVKLT-IDKSRYEDYIHANYVKTNYLRNTFICTQGPLQHTIIDFWRMIFQERAESILMLCktmeegRPKCVG
. . || .|| |||. ... | ..||| .. . ||| | .|. .. .| .||||. |. ||||||.. .. .|..| . ||
nladqtfanldqnkdknriinilafdknvvklerliGeefsdyinasfvtGyqrkdkyiaaqGPldntladfWrmiweyncstivllt......kdkcsq
YWPSLGV-TETYGCIRVTNMGESSDefeicnlavtFVPDNVPVDEQPANLKELRVNLIKWPNWPDRGVPDEKCHTV---PQ-RLLAQVRH--GPCVVHCS
||| .| .| . ..|. . |... .| .. . |. . ... .. ||| |||| . . | | . . . |||||
ywplkivikeerfkvkvdsveetae..........yvvrdielsedgkekdirkitqfhflGwpdvGvpdypsdlmrlvkkvrhltskenhranivvhcs
AGIGRTGCVVALEFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMIA-FARGETDVSEK
||.|||| ..|. ..... .|| ... .||.|| . .| .|| .|. .. . | .||.
aGvGrtGvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleehlfghsdvamp
|
|||||||||
subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 84-343 | 1.6e-46 | 154.1 | In-house | 14-266 (284) | alignment | ||
Range on Protein: 84-343
Range on HMM: 14-266/284.0
DSSLTFEAFKQNMHKNRYSDVVCRDTTRVKLT-IDKSRYEDYIHANYVKTNYLRNTFICTQGPLQHTIIDFWRMIFQERAESILMLCktmeegRPKCVGY
. || .|| |||. ... | ..||| .. . ||| | ... .. .| |||||. |. ||||||.. .. .|..| . || |
gtdqtfanldqnkdknrighilafdknvvklerliGeefsdyinasfitGyqrkdkyiatqGPldntladfWrmiweyncstivllt......kdkcsqy
WPSLGV-TETYGCIRVTNMGESSDefeicnlavtFVPDNVPVDEQPANLKELRVNLIKWPNWPDRGVPDEKCHTV---PQ-RLLAQVRH--GPCVVHCSA
|| .| .| . ..|. . ||.. .| .. . |. . . ... .. ||| |||| . . . | | . . . ||||||
wplkivikeerfkvkvdsveesee..........yvvrdielsedgkekdirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsa
GIGRTGCVVALEFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMIA-FARGETDVSEKA
|.|||| ..|. ..... .|| ... .||.|| . .| .|| .|. .. . | .||.
gvgrtgvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleehlfghsdvalpd
|
|||||||||
subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 68-356 | 1e-45 | 151.1 | In-house | 22-297 (315) | alignment | ||
Range on Protein: 68-356
Range on HMM: 22-297/315.0
GIEGLAKQYRKLDAQQDSSLTFEAFKQNMHKNRYSDVVCRDTTRVKL-TIDKSRYEDYIHANYVKTNYLRNTFICTQGPLQHTIIDFWRMIFQERAESIL
.|. ..| . | | .| .|||| ... | .||.| ... ||. ||... .. .|..|||. .. ||||..|.| |.
tkngfkqdyesipggqlhpldvakkienkqknryiniiaydksrvqlpllendphsdyvnanfidGynkkrryiaaqgpnvasvkdfwrlvfeedigkiv
MLCKTMEEGRPKCVGYWPSLgvTETYGCIRVTNMGES-SDEFEICNLAVTFVpDNVpvdeqpanlKElrVNLIKWPNWPDRGVPDEKCHTV------PQR
|| ...|. . |. ||| .|| | || . | .|. . |.|.| ||. .| | ... ||| ||| . |
mltnlvegekrkaekywpdk..kviyGkitvtrkseevnteytvrtlsvvfg.dni.........re..vvqlhytswpdmgvpkytiplmnlirtvkqh
LLAQVrhGPCVVHCSAGIGRTGCVVALEFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVM-IAFARGETDVsekalaAADAFLKSYDE
..| |. |||||||.|||| ..|. .... .| ..|| .|..| . .|. || .|. .. .| |.| . | | .|..||
htnsv..gaivvhcsaGvGrtGtfitldavldqaeaenaidvynfitgvrqnrikmvqvaeqyqfiydalletfvcgdtsi......aqdlylqryds
|
|||||||||
subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 60-341 | 1.3e-45 | 150.3 | In-house | 1-277 (281) | alignment | ||
Range on Protein: 60-341
Range on HMM: 1-277/281.0
FIIATEKLGIEGLAKQYRKLDAQQDSSLTfEAFK--QNMHKNRYSDVVCRDTTRVKLTI--DKSRYEDYIHANYVKTNYLRNTFICTQGPLQHTIIDFWR
| ....|. .. . ... .| . | | .|. | .||||... | | .||.| . . |||||||... .|. .| |||| . | ||||
famssqkmtlddfkqefsnlpgdppsdlc.tvfnqpvnnkknrylnipcldisrvqlkvkmpnknstdyihanyirspflkrgyiltqgpkketradfwr
MIFQERAESILMLCKTMEEGRPKCVGYWPSlgvtETYGCIRVTNMGESSDEFEICNLAVTfVPDNVPVDEQpANLkelrVNLIKWPNWPDRGVPDEKCht
||.|| . .|.|||. .| | || |.| ... |... .. | .. . . || |. . . . | . | .||| ||.
miwqenttaivmlcqfletnrekcaeyfpr....nahcclqfdklsvsyedstvnkslvt.trlnlsyege.trl....ithwlwkewpdwqvpesse..
VPQRLLA--QVRHGPCVVHCSAGIGRTGCVVALEFAYNKLDRGLKV-DFEEIITELRK-QRAQCIQTEIQYLYIHRVMIAFARGETDVSE
| ..| . | | |.|||||.||.| ..|.| | . . . . | ..|.. || || .|| ||. | .|.. | ...|
vmlkilrkirarstppvihcsagvgrsgtlmaveialqsihshftlpdikqivshlrvtgraasvqtlqqymliwkvlldfgvaykqite
|
|||||||||
subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 54-332 | 2.2e-45 | 149.9 | In-house | 4-277 (287) | alignment | ||
Range on Protein: 54-332
Range on HMM: 4-277/287.0
VETLNNFIIATEKLGIEGLAKQYRKLDA--QQDSSLTFEAFKQNMHKNRYSDVVCRDTTRVKLTidkSRYEDYIHANYVKTNYLRNTFICTQGPLQHTII
|| ...|. .. | || .|. |. |.. ..| . .|| .|||..... .| || | . .||| | .... .. || ...|. .|.
vekfgefvakghakgnegfknqftvleqvtqredevthniasqnkdknRltqilvpdnyrvllk...gehpdyinavfidgykekkafiiaesPmfntar
DFWRMIFQERAESILMLCKTMEEGRPKCVGYWPSLGVtETYGCIRVTNMGESSDEfeicnlavTFVPDNVPVDEQPANLKELRVNLIKWPNWPDRG-VPD
.||..| ... . |.|||. .|. . .| |||. ..| ... . | . .. .. | .. . ....|. . ||...| |..
nfWkliddrnvtaivmlcqekendeevcyqyWpeeks.vvlGeyniellneevna........gyierklevknknkagdkqqvkqyqitnWdstgkvte
EKC--HTVPQRLLAQVRH--GPCVVHCSAGIGRTGCVVALEFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMIAF
. . .. .| .. .. |||||...||.. .| . . || .. .| ... . | |. . .|| || .| .....
pqtillvieemyktqrkrgntsivvhCsdtvGrsamfcaaattinkckteGviDvfqvlksqriqkpgsvqtveqykfindivley
|
|||||||||
0041856 | (Phosphotyrosine protein) phosphatases II | 95-334 | 2.2e-44 | 146.5 | In-house | 1-172 (182) | alignment | ||
Range on Protein: 95-334
Range on HMM: 1-172/182.0
NMHKNRYSDVVCRDTTRvkltidksrYEDYIHANYVKTNYLRNTFICTQGPLQHTIIDFWRMIFQERAESILMLCktmeegrpkCVGYWPslgvtetygc
|..||||||... | .| . |||.||.. .. ..||.|||||..|. ||.||. ... .|..|. .. |||
nldknrysdilpydhsr.........dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt.........eelywp..........
irvtnmgessdefeicnlavtfvpdnvpvdeqpaNLKELRVNLIKWPNWPDRGVPDekcH--TVPQRLLAQVRHGPCVVHCSAGIGRTGCVVALEFAYNK
.| | . ... .||| |||| .. .. ..||..||||||.||||..||. . . .
..................................ellerlgiqylylpwpDhgvpd...ldelldfieevleeggpvlVHCsaGvgRtgtlvaaylmkkl
ldrglKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMIAFAR
.|..||.. ..|..| ....|. || ...... . .
.....gvsleeavklvrsrRpgmvitpnqyfflqlallelll
|
|||||||||
subfamily_egg_pd | Subfamily egg | 82-340 | 2.4e-43 | 143.0 | In-house | 27-277 (307) | alignment | ||
Range on Protein: 82-340
Range on HMM: 27-277/307.0
QQDSSLTFEAFKQNMHKNRYSDVVCRDTTRVKLTIDKSRY-EDYIHANYVKTNYLRNTFICTQGPLQHTIIDFWRMIFQERAESILMLCKTMEEgrPKCV
.. ||| | . |..| | | |.|..|||| . . .| .|.||||.|| . | |.||..| ||. | |||||.|||. . |.|| . | .|
vdeislttaasdnnlekarskrvhckdssrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvddfwrmvfqeevqyivmltsrkes..erce
GYWPSLGV---TETYGCIRVTNMGESSD---EFEICNLAVtFVPDnvpvdeqpanLKELRVNLIKWpNWPDRGvpDekcHTVPQRLLAQVRH--GPCVVH
||| | .|..|.. | | . .| . .| .|. .. .. .. . | | |.| ..|. | ||.
yywpkaesdslvtvpGslrienlkvdskadplfrvtklkl.vGgd..........deerflehwqg.dvnnss..d...vysplrvlrklrnlskpvvvq
CSAGIGRTGCVVALEFAYNKLDRG--LKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMIAFARGETDVS
. |. .....||.| | .| || | . . ||..| ... ..||...|... | | .
dilGvskaatlvaieiallsllrGpitkslvlravvflrlrrrlsvesvllylfvyrlvlfffrdvigsa
|
|||||||||
subfamily_PTPN23_pd | Subfamily PTPN23 | 70-334 | 8.2e-43 | 141.3 | In-house | 15-281 (288) | alignment | ||
Range on Protein: 70-334
Range on HMM: 15-281/288.0
EGLAKQYRKLDAQQDS---SLTFEAFKQNMHKNRYSDVVCRDTTRVKLTidkSRYEDYIHANYVKTN-YLRNTFICTQGPLQHTIIDFWRMIFQERAESI
.| |....|. .|| . . . | . .|||. |.. | .|||| . .||| | .|| .||.||.||| |. |||.|....... |
taldkkfkeleqkqdkearkrsiaiaklyseknrsrdilPyDhnRvklr...gskDDYinAsfvkdlspgcPdfiatqaPlqstlnDFWlmvyeqkssvi
LMLCKTMEEGRPKCVGYWPS-LGVTETYGCIRVTNMGESSDEfeicnlavTFVPDNVPVDEQPANLKeLRVNLIKWPNWPDRGVPD------EKCHTVPQ
|| . | |.||. |||. | |...| ..|| . . | |.| .. .. ..|. . | .... .||. |||. . . | .
VmllskeelgkpkvdrYwPedkgetvkfgdlsvtlksvrete........thvervlkletldadav.ksvshlqltsWpelGvPasPetllqfldeves
R--LLAQVRHGPCVVHCSAGIGRTGCVVALEFAYNKLDRGLK-VDFEEIITELRKQRAQCIQTEIQYLYIHRVMIAFAR
. . | |||||||.|||| . . | ..|..| .| ... ||.|| .|.. |. ... ||
ayeavqrksktPlvvhCsaGvgRtgvfalvyaavrelekgnglldiiqvvsrlreqRrfmvqekeqlkfsyeavleaar
|
|||||||||
subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 87-330 | 8.2e-43 | 141.5 | In-house | 40-276 (439) | alignment | ||
Range on Protein: 87-330
Range on HMM: 40-276/439.0
LTFEAFKQNMHKNRYSDVVCRDTTRVKL-TIDKSRYEDYIHANYVKTNYLRNTFICTQGPLQHTIIDFWRMIFQERAESILMLCKTMEEGRpkcvgYWPS
.. | . . |||| ||. | ||| | | . || |||.| | . .| |||| ..| ||||....... |.||.. .| . ||||
aslaaqeydqtknrykdvgafdhtrvtlqeipgvphshyinanyikGyyddklyiatqgpkkettddfwrlviekktvtivmltnlvesyk.....ywps
LGVTeTYGCIRVTnmgeSSDEFEICNLAVTFVpdNVpVDEQPANLKELRVNLIKWPNWPDRGVPDEKCHTVPQ-RLLA----QVRHGPCVVHCSAGIGRT
. . || | | . |. | .. . .| ..|. . || | ... |||. || . | . | . . || |||||||.|||
daev.cygdiavr....vdrnielpnyvirgf..kv.fnerdttekertvlqfhyiawpdknvpaqashvldflrainsandkeeygpvvvhcsagvGrt
GCVVALEFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMI
| ..||. | ..| ||| . |.. ||||| | .|. ||..|. ..
Gtiialdialeqlklenkvdikgivkvlrkqrkqmvqalcqyvfiynavl
|
|||||||||
subfamily_PTPN14_pd | Subfamily PTPN14 | 82-333 | 8.3e-43 | 141.5 | In-house | 36-296 (300) | alignment | ||
Range on Protein: 82-333
Range on HMM: 36-296/300.0
QQDSSLTFEAFKQNMHKNRYSDVVCRDTTRVKLTIDKSRYEDYIHANYVKTNY--LRNTFICTQGPLQHTIIDFWRMIFQERAESILMLCKTMEEGRPKC
..|. |. . ..| .|||. ||. . .||.|. | ..|| | .|. . ..| .||||..|. |||.|.... . |.|| .. |.|. |.
redallstaklpenaeknrfkdvlPyednrvelsptkenstgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivmlteeeedgkeks
VGYWPSLG---VTETYGCIRVT-NMGESSDEFEICNLAVTFVPDNvpvdeqpanlKELRVNLIKWPNWPDRGVPDE---------KCHTVPQRLLAQV--
. |.|.|. | ..| .|| .. |.|| . | . ..| . .| | ... .|||.|||.. . . | .. .|
fkyfPkleskkktvefgkfkvttkfsedsdsvittglklkhlpsk..........eertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseves
--RHGPCVVHCSAGIGRTGCVVALEFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMIAFA
.. | .||||||.|||| .. .. . |. . ..| ..... ||.|| .|| || ....|.| .
keskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLreqrmllvqtlaqYkfvYkvlikyl
|
|||||||||
subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 69-350 | 9.5e-43 | 141.5 | In-house | 22-306 (325) | alignment | ||
Range on Protein: 69-350
Range on HMM: 22-306/325.0
IEGLAKQYRKLDAQQDSSLTFEAFKQNMHKNRYSDVVCRDTTRVKL-TIDKSRYEDYIHANYVKTNYLRNTFICTQGPLQHTIIDFWRMIFQERaESILM
.|.|... | ... . . . .|. |||. .|| | .|| | | ... ||| |.|.... ...|. .| || .|| |.||.... | |...
qdgfahefgllpsddgiakkvamkpenkaknrfknvvaldksrvvletkkddpssdyinasylrddkkkdvflaaqaPltatindlWrlvldWr.csvvv
LCKTMEEGRPKCVGYWPSL-GVTETYGCIRVTNMgeSSDEFeicnlaVTFVPDNVPVdEQPANLKELRVNLIKWPNWPDRGVPDEKCHTVP---------
. ...| .| ||| | . |.| ..| . . .|. .| . | |. . . . |. .. |.| ||. . ..
vlneldlgkdrcavywpkemgksktfGglevklr..tieei......sdyvhrvldv.kqvkkGetrsvkqfqlqswddmGvqkrpatlisilqlvkavs
QRLLA-QVRHGPCVVHCSAGIGRTGCVVALEFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMIAFA-RGETDVSEKALAAADAF
.|. | .| .||||||.|||| ..| | .|. .|| . . |||.| . ..| || |. .. . |.||| .. | .
ervtantkastpilvhcsaGvGrtGvfislysalakvieesrvdifgfvkklrkdrpsmvetvdqyiliyealveaymsgntdvpvssfeaklss
|
|||||||||
subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 86-329 | 3.2e-42 | 139.5 | In-house | 35-273 (315) | alignment | ||
Range on Protein: 86-329
Range on HMM: 35-273/315.0
SLTFEAFKQNMHKNRYSDVVCRDTTRVKL-TIDKSRYEDYIHANYVKTNYLRNTFICTQGPLQHTIIDFWRMIFQERAESILMLCKTMEEGRPKCVGYWP
. ..|..|||| ... |..|||| ||.| .||| | |.|. ...|..||||. .. |||||..||.. .| |. | |. . || |||
rqrvaretinfkknryknilPldsarvkleviddsPdsdyinasyiksvdddkayiasqgPlkasvddfwrmvlqekvttivmvtkkqegdkikcrqywP
S-LGVTETYGCIRVTNMGESSDEFEICNLAVTfvpdnvpvdEQPAnlKELRVNLIKWPNWPDRGVPDEKCHTVpqRLLAQVR------HGPCVVHCSAGI
. . .| |.|. . ..| . || . . .| .. .|||.||. . . .|. .|. . . .||||||.
drkadsvefGsikvellsleadtdgvarklvt.........rkse..esrtvtqfqftewPdkGvdkqtssll..klikevkadngkkefsllvhcsaGv
GRTGCVVALEFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVM
|||| |.... ... |. || .....||..| . .||| .| .|. ..
GrtGvvisidevvaqikrtrsvdvfnfvknlrakrpylvqteeeyafiydav
|
|||||||||
subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 83-334 | 4.8e-42 | 138.7 | In-house | 24-278 (287) | alignment | ||
Range on Protein: 83-334
Range on HMM: 24-278/287.0
QDSSLTFEAFK--QNMHKNRYSDVVCRDTTRVKLTIDKSRYEDYIHANYVKTNYLRNTFICTQGPLQHTIIDFWRMIFQERAESILMLCKTMEEGRPKCV
. |..|| | . ...||||.||. | ||| |. . ||| |||| . ..||..|||. |. ||||.....|. |.... . .||.| ||
esstatfkaaeelaavkknryadvlPiddtrvllsaegelGsdyinanyvasytddeafiaaqgPiaatvrdfwravletrsasvitmtreveearlkcy
GYWPSLGVTETYGCIRVTNMGESSDEFEICNLAVTFVpdnvPVDEQPANLkelrVNLIKWPNWPDRGVPDE-----------KCHTVPQRLLAqvRHGPC
||| | | |. . . | | . |. . .. . |.. |. ... .|||.... | | .| . ||
kywPerevPmrvGGysvvlldydikePeygvralrli....dletrearv....vkqldllswPdkvlaPtavglirfvldvkqhielardas..evGPl
VVHCSAGIGRTGCVVALEFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMIAFAR
|||...||||.| ..|. ..| .|| .. ||..|| .|. .|. .. .... .
vvhddvGiGrsGillatlvlvsrledlGrvdvaavvirlreyraalvqavvqlrllyealvtyyk
|
|||||||||
subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 74-338 | 6.3e-42 | 138.4 | In-house | 13-272 (283) | alignment | ||
Range on Protein: 74-338
Range on HMM: 13-272/283.0
KQYRKLDAQqDSSLTFEAFKQNMHKNRYSDVVCRDTTRVKLTIDKSryeDYIHANYVK---TNYLRNTFICTQGPLQHTIIDFWRMIFQERAESILMLCK
.....| | . . .. ..| .|||. ..| | ||.| . ||| | .. . . .| .|.||..|..|||.|.|.|.. .|.|| |
evlkrlsvp.dldadiasadenkrknrnqeivpadqwrvelksesr...dyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekitaivmltk
TMEEGRPKCVGYWPSLGvTETYGCIRVTNMGES-SDEFEICNLAVTFVpdnvpvDEQPANLKELRVNLIKWPNWPDRGVPDEK-CHTVPQRLLAQVRHGP
.|. | || |||. | .| || || | |. | | .| . ..| .| | .. . . . . | . ..||
lqedlrikCsqyWPkrG.sedyGeftvtlrkettsnsfiikelllrvn......ssakstlllahyqvidWleygeqaiinslvkfnkvislqteskkgP
CVVHCSAGIGRTGCVVALEFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMIAFA-RGETD
|||||.|||||. .|. . ... || .... .|.|| .|| || .| ... | |.|.
ivvhCstgiGrtavfiaasasvkdaltesvvdvfavvkimreqrmmavqtldqyklvhelvleqalcgdtq
|
|||||||||
subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 78-340 | 8.5e-42 | 138.0 | In-house | 18-277 (285) | alignment | ||
Range on Protein: 78-340
Range on HMM: 18-277/285.0
KLDAQQDSSLTFEAFKQNMHKNRYSDVVCRDTTRVKLtidKSRYEDYIHANYVKTN-YLRNTFICTQGPLQHTIIDFWRMIFQERAESILMLCKTMEEGR
|. |. |.. | |||.|| | . ||| | | . |||||.... ..|.| ||||| |. |||.||.||. .|||| .| |
kikgymppnctytayeanpdlnryadvrcieetrvvl...knhdrdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggv
PKCVGYWPS-LGVTETYGCIRVTnMGESSDEfeicNLAVTFVPDNVPVDEQPANLKELRVNLIKWPNWPDRGVPDEKCHTVP-QRLLAQV--RHGPCVVH
|| |.| || .| .| . | .| .| | . .. . |. . | .| .. | |||. |.. . . . .| . | .||
ekcalyypeklgevvkfgkyeit.lteckee....aiagtilnaltvintedasseplymnhvqvpwwpdqlapedarpmielykwvkkvnpkekpicvh
CSAGIGRTGCVVALEFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMIAFARGETDVS
||||.||| .| ...| .. .... .|. |.| | |..|. .|.|... |.. . || |
csagvgrtatfvgidyatirimenpniemldivremramrfqavqshmqflflyvvlmeyfigegvve
|
|||||||||
subfamily_PTPN9_pd | Subfamily PTPN9 | 59-255 | 3.1e-41 | 136.3 | In-house | 5-195 (297) | alignment | ||
Range on Protein: 59-255
Range on HMM: 5-195/297.0
NFIIATEKLGIEGLAKQYRKLDAQQDSSlTFEA--FKQNMHKNRYSDVVCRDTTRVKLT-IDKSRYEDYIHANYVKTNYLRNTFICTQGPLQHTIIDFWR
... .. |..|| |.| .. ... . ||.| . |..||||.||.| | |||.|. .|. . |||.||.| ...|| |||||..|. ||||
elvayvkekgkrGlskeyaeirnepveG.tflasklranleknrytdvlcydetrvvlakvdedeasdyinanfvdGykqkkafiatqGplkktvsdfWr
MIFQERAESILMLCKTMEEGRPKCVGYWP-SLGVTETYGCIRVTNMGESS-DEFEICNLAVtfvpDNVPVDEQpanlkeLRVNLIKWPNWPDRGVPDEKC
|...... |.| ...|.|| || ||| . . .. .| ..|.|. . ..... | . .|| .|. .| . ||| |||..
mvWeqevlvivmttrvvergrlkcgqyWpleeessaefgdlsvsnveveeeedykvrvlei....knvktees......rkvthfqflsWPdyGvPssaa
HT
sl
|
|||||||||
subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 70-331 | 3.1e-41 | 136.0 | In-house | 15-291 (301) | alignment | ||
Range on Protein: 70-331
Range on HMM: 15-291/301.0
EGLAKQYRKLDAQQDSSLTFEAFKQNMHKNRYSDVVCRDTTRVKLTIDKS---RYEDYIHANYVKTNYLRNTFICTQGPLQHTIIDFWRMIFQERAESIL
.....||..|. ..| | | . ..| . ||. ... | |. |. .. ..|| |.|.. .. || .|||...|..||||.|.||. ||.
nkfeeqykelkegedksctvglseenkalnrfknitvyddnriilkpkpnldlcqreyinasyidgysekkkfiaaqgpmkktlvdfWrliwqekpvsiv
MLCKTMEEGRPKCVGYWPS-LGVTETYGCIRVTNMGES-SDEFEICNLAVTFVpDNVP---VDEQPA---NLKELRVNLIKWPNWPDRGVP---DEKCHT
|.... |. . || |||. .|..| . || . | .| | .|.|. | . . . . . | .. .||. || .
mvtnlkegtkskceqywpnseaeseefgpftvtlvneqvyPdfvirqlnvkiq.dgsnngyierkfkvksdksswdvlqlqvtdWpqdGvvreprtvLqv
VPQRLLAQ--VRHGPCVVHCSAGIGRTGCVVALEFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMIA
. . . .| . || |||||....|.| .... . . || ... .|... ..| || |. |.
iddvihrqqkigggpvvVHCSdtVsrsGvYcsvsiglEQckaegVVdvfqvtkavrrskpgaVtTLeqytsiydvidm
|
|||||||||
subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 93-329 | 1.1e-40 | 134.3 | In-house | 41-272 (515) | alignment | ||
Range on Protein: 93-329
Range on HMM: 41-272/515.0
KQNMHKNRYSDVVCRDTTRVKL-TIDKSRYEDYIHANYVKTNYLRNTFICTQGPLQHTIIDFWRMIFQERAESILMLCKTMEEGRPKCVGYWPS-LGVTE
. | .|||| ... |..|||| |. . .||. | |... ...|..|||.. .. ||||...||. | |. | |. . || ||| | .
einfkknryknilPydsvrvklevindnPhsdyfnasyipsfdndkayiasqgPnkasvddfWrlvlqenvttiamvtklkegdkikcgkyWPdkpgdsv
TYGCIRVTNMGESSDEFEICNlAVTFVPDNvpvdeqpanlKELRVNLIKWPNWPDRGVPDEKCHTvpQRLLAQVR--H----GPCVVHCSAGIGRTGCVV
.| |.| . ... | .| . .. . | .. .|||.||| . .|. .|. | | ..|||||.|||| |.
kfGsikvelvsleactggikr.kltvlkgd..........dsrtvtqfhfteWPdkGvpkhtssl..lklikevkadhgqythpliihcsaGvGrtGvvi
ALEFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVM
... . . || ...| .|..| . .||. || .|. ..
sidsvvahakttrmvdvfnfvtnirqkrpylvqtqeqyafiygav
|
|||||||||
subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 72-334 | 2.2e-40 | 133.3 | In-house | 21-277 (312) | alignment | ||
Range on Protein: 72-334
Range on HMM: 21-277/312.0
LAKQYRKLDA-QQDSSLTfeAFKQNMHKNRYSDVVCRDTTRVKLTIDKSRyedYIHANYVKTNYLRNTFICTQGPLQHTIIDFWRMIFQERAESILMLCK
|.|.|. . .|| | || . ||| .. | | | |. |. |||||.|| . |.||||||. |. ||.. . . ||..||
ltkeykavgnivsdsect..aflkfkdlnrypniqcwdrgrftlagdenf...yihanfvkictkperfvctqgplentcthfwqlalslgstsiillcg
TMEEGRPKCVGYWPSLGVTETYGCIRVtnMGESSDEFEICNLAVTFVPDNVPVDEQPANLKELRVNLIKWPNWPDRGVPDeKCHTVpQRLLAQVRH--GP
.|.| ||. | . || |. | || . . | | .| ..| .| ||| |.|| | | .|||. |.. |
fvedgsekcakyisdivgfvdledhrv..yteycteieiggkskdkithrvlkvvvkatgqesklnhyqwaswpdhgmpd.scdta.lrllsavkkdkkp
CVVHCSAGIGRTGCVVALEFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMIAFAR
. |||||.|||| .. .| | | . .. |||.||. ... ||.| |... |
viahcsagvgrtgtlaliesmiaalrhprkqnvkdsfvllrkdrarsvrvfpqyvyalrcvlefly
|
|||||||||
subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 91-330 | 4.5e-40 | 132.6 | In-house | 46-281 (297) | alignment | ||
Range on Protein: 91-330
Range on HMM: 46-281/297.0
AFKQ-NMHKNRYSDVVCRDTTRVKLTIDKSR-YEDYIHANYVKTNylRNTFICTQGPLQHTIIDFWRMIFQERAESILMLCKTMEEGRpKCVGYWPSLGV
| |. |..|.||.... |. |||| | . ||. | .||.| .. .|.|| | . |. |||.|...|.. |.|| . |. . || ||. ||
aekkvnfeksRYkniLPydssRvkLaivnddpdsDyvnasfvkgn..khrlittqmPmkatvadfWamvldeqvstivmlnddnerdk.kcaryWsdkgv
TEtYGCIRVTNMGESSdefeicnlAVTFVPDNVPVDEQPANLKELrVNLIKWPNWPDRGVPDEKCHTVPQRLLAQVR-------HGPCVVHCSAGIGRTG
|. .| . |. . |. |. .. | .. | . . |. .. .|||. |. .. . . |. .|| .|| .|||.||.||||
tt.fGdvsvvllsvse........reGfikrelevtkgkakarrv.vkqyqfveWPdkaverkdsassllklisevrkdfsqnaegPllvhclaGvGrtg
CVVALEFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMI
..... . | .|| .... ||..| . .||. || ... ...
vlltidsvvaeakrekevdifglvkklrqerpylvqtkeqykfvyvavl
|
|||||||||
subfamily_PTPN1_pd | Subfamily PTPN1 | 84-327 | 1e-39 | 131.0 | In-house | 21-265 (290) | alignment | ||
Range on Protein: 84-327
Range on HMM: 21-265/290.0
DSSLTFEAFKQNMHKNRYSDVVCRDTTRVKLTIDKSryeDYIHANYVKTNYLRNTFICTQGPLQHTIIDFWRMIFQERAESILMLCKTMEEGRPKCVGYW
| . . ...| .||| || | .|.|| .. ||| |. |. . .. .| ||||| .|. ||.|...... ...|| | .|... ||. ||
dfptreaklpenrnlnryrdvspydhsrikleradn...dyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvvekeqikcaqyw
PSLGVTETYG----CIRVTNMG-ESSDEFEICNLAVTFvpdnvpvdeqpANL-KELRVNLIKWPNWPDRGVPDEKCHTVpqRLLAQVR--------HGPC
|. ... ..|. . |..... . | .. . . . .. ||| |||. . ..| .|| .||
Pqgeeekellledtklkvkliseerksyytvrllelen...........lktqetreilhfhyttwpdfgvpespaafl..kflfkvresGslssdvGpa
VVHCSAGIGRTGCVVALEFAYNKLDRGLK---VDFEEIITELRKQRAQCIQTEIQYLYIHR
|.||||||||.| .. .. .... . || .. . ||||.| ||| | . .
vihcsaGiGrsGtfclvdtclvliekkddlssvdikkvllelrkyrlGliqtadqlrfsyl
|
|||||||||
0049772 | (Phosphotyrosine protein) phosphatases II | 80-332 | 1.1e-38 | 129.1 | In-house | 31-279 (314) | alignment | ||
Range on Protein: 80-332
Range on HMM: 31-279/314.0
DAQQDSSLTFEAFKQNMHKNRYSDVVCRDtTRVKLTIDKSRYEDYIHANYVKTNylrNTFICTQGPLQHTIIDF----------WRMIF--QERAESILM
. .. .... . |..|||| |... | .||.| . |||.|.||.. ..||.|||||..|..|| |||.. . . | |
svlpeltilvadlflnrdknryldilpad.nrvilpglpvsgsdyinasyvdgf...lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivm
---------------------LCKTMEEGrpkcvgywpslgvtetygcirvtN----------MgessdefeicnlavtfvpdnvpvDEQ--PANLKELR
|.. .. | | .|. | ...|
srdevladelsrLdaAlgKtpllildgng.......................neptaadlellk.......................eelydpelferlg
VNLIKWpNWPDRGVPDEKCHTVPQRLLAQ-VRHGPCVVHCSAGIGRTG--CVVALEFAYNkldrglKVDFEEIITELRKQRA-----QCIQTEIQYLYIH
.... . ..|| ..|... ... . ..|| .|||.||.|||| .|.|. .. .|..||.. ..|..| .|.. .||..|.
ikylri.pvpDgsaplledfdeflefieeadkggpvlvHCkaGkgRtgtfvvaaylmkll......gvsleealedvrlkRpinpnpgfieqleqyefil
RVMIAF
... .
ealley
|
|||||||||
0046846 | (Phosphotyrosine protein) phosphatases II | 120-331 | 4e-38 | 126.3 | In-house | 10-171 (176) | alignment | ||
Range on Protein: 120-331
Range on HMM: 10-171/176.0
RYEDYIHANYVKTNYlrntFICTQGPLQHTIIDFWRMIFQERAESILMLCKTMEEGRPKCVGYWPSlgvTETYGCirvtnmgessdefeicnlavtfvpd
. |||.||.. ... .|.||||| .|. ||..|..... . ...|.. .| || || ||| |..|.
ldldyinanlilgsr....piatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpe...leklgi.........................
nvpvdeqpanlkelrvnLIKWPNWPDRGVPDEK--CHTVPQRLLAQVRHGPCVVHCSAGIGRTGCVVALEFAYNkldrGLKVDFEEIITELRKQRA-QCI
... .||| |||| . .. . . |. ..|| .|||||||||||..||. . . .. ||.. ..|.|| ...
.................qylhlpwpDhgvpdlelllellefirealkeggpvlVHCsaGigRtgtlvaayllel....ekglsveealalvreqRplgav
QTEIQYLYIHRVMIA
||. || ......
qtpeQyrflyefell
|
|||||||||
0043147 | (Phosphotyrosine protein) phosphatases II | 121-326 | 1.7e-37 | 124.1 | In-house | 4-154 (172) | alignment | ||
Range on Protein: 121-326
Range on HMM: 4-154/172.0
YEDYIHANYVKTNYLRNTFICTQGPLQHTIIDFWRMIFQERAESILMLCKTmeegrpkcvgywpslgvtetygcirvtnmgessdefeicnlavtfvpdn
..|||.|.|....| . ||.|||||..|. |||||. .. |..|..
gsdyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltel.................................................
vpvdEQPANLKELRVNLIKWPNWPDRGVPdEKCHTVP-----QRLLAQVRHGPCVVHCSAGIGRTGCVVALEFAYnkldrgLKVDFEEIITELRKQRAQC
. .. | | . . . .||| ||| . ..|||. ..||..||||||.||||..||. . |....||.. ..|..| ..
....lydpellerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml......lglsleeavalvrekRpga
IQTEIQYLYIH
.|.. || ...
vqnpsqyrfly
|
|||||||||
subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 94-329 | 3.1e-37 | 123.1 | In-house | 2-235 (237) | alignment | ||
Range on Protein: 94-329
Range on HMM: 2-235/237.0
QNMHKNRYSDVVCRDTTRVKLTIDKSRyEDYIHANYVKT-NYLRNTFICTQGPLQHTIIDFWRMIFQERAESILMLCKTMEEGRPKCVGYWPSLGVTETY
.| ||||...|. | .|| | | ||| |.|.| . ...|..||||. . |||.|..||. |.|| .| . || |||| ..|
enkiknrygnivaydhsrvvlkgagsg.sdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpstdqpaay
GCIRVTNMgeSSDEFEicNLAVTFVpdnvPVDEQpANLKELRV-NLIKWPNWPDRGVPDEKCHTV--PQRLLAQVRH----GPCVVHCSAGIGRTGCVVA
| . |. .|| . .| . . .. .|||.|. .. |||||||.. . . .... . .| || ..|||||.|||| ..
gvltvslk..kkeefs..dytvrsl....llskr.ltlkevrlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflv
LEFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVM
.. . || . . . ..| |||. ||..||...
idamlrqakekkvvdiynyvysieedrpyiiqtkdqyvfihqti
|
|||||||||
0036282 | (Phosphotyrosine protein) phosphatases II | 122-327 | 1e-36 | 121.6 | In-house | 2-164 (174) | alignment | ||
Range on Protein: 122-327
Range on HMM: 2-164/174.0
EDYIHANYVKTNYLRNTFICTQGPLQhtiidFWRMIFQERAESILMLCKTMEEGRPKCVGYWPSlgvtetygcirvtnmgessdefeicnlavtfvpdnv
.|||.|.... .| . .|..||||. ||.|..... ....||.. .| |. || |||.
sdyinaspldlsyitprliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe....................................
pvdeqPANLKELRVNLIKWPNWPDRGVPDE----KCHTVPQRLLAQVRHGPCVVHCSAGIGRTGCVVALEFAYNKLDrGLKVDFEEIITELRKQRAQCIQ
. | . ... .|||.|||| .. .. |.. ..||..||||||.||||..||. . | || ... |||.|| ...|
.....lredlerlgiqylylpwpDhgvpdlsillefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvq
TEIQYLYIHR
|. || ...
tpsQyrflyy
|
|||||||||
subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 96-325 | 1.7e-35 | 117.3 | In-house | 51-273 (301) | alignment | ||
Range on Protein: 96-325
Range on HMM: 51-273/301.0
MHKNRYSDVVCRDTTRVKLTIDKSRYEdyIHANYVKTNYLRNTFICTQGPLQHTIIDFWRMIFQERAESILMLCKTMEEGRPKCVGYWPSLgVTETYGCI
.|.|| | |. .| |.. | | ||||...|. . ||.|||||. | ||| |. | | | ||....|. || | |. ..|.
kdkhryptvPckPstavevivdGkrvP..ihanwiptsGhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvk.isekldig
RVtNMGESSDEfEICNLAVtfVPDNVPVDEQPANLKELRVNLIKWPNWPDRGVPDEKCHTVPQRLLAQVRHGPCVVHCSAGIGRTGCVVALEFAYNKLDR
| .. . | | | . . .. | . ... | .. .|.||||| . .. |.. . | ||||||||||. . .. |. ....
rf.kikiknke.lilnkki..skrtlevedstgkfatrtvthyqysewtdrgvPkshaelfdlmelvkksekPivvhcsaGiGrsvafigteylarevea
GLKVDFEEIITELRKQRAQCIQTEIQYLYI
.... | . .||..| . .||. | ..
dptieltealkhlrehrwngvqtnsqlywm
|
|||||||||
subfamily_CG7180_pd | Subfamily CG7180 | 92-330 | 3e-35 | 116.3 | In-house | 39-287 (296) | alignment | ||
Range on Protein: 92-330
Range on HMM: 39-287/296.0
FKQNMHKNRYSDVVCRDTTRVKLT-IDKSRYEDYIHANYVKTNYLRNTFICTQGPLQHTIIDFWRMIFQERAESILMLCKTMEEGRpKCVGYWPSLGvTE
|.|. |||. .|| | .|| |. .| .||| | || . . .| |..| ..|. .|||....| .... .|.||.. . .. ||| . |
rkenreknrdvkvvPyDynRvvLekldGeeksdYinavyvdsflkkkeyivteapkketvdefWrlvydeeisavvvLtktfdfak.mypsywpnks.ke
TYGCIRVTNMGE-SSDEFEICNLAVTFVPDNVPVDEQPANLKELRVNLIKWPNWPD-RGVPDE-----KCHTVPQRLLAQV----RHGPCVVHCSAGIGR
|| | | . | . ...| .. .| . |.. . .. | |... |. || . . . .| .|| ||..| | .|
qygeifveiveekqyanlkirtfkltkkivalteqekqvkaetRivklfqlteWeledkvPlstnalielrrrvrlwrekvdedpeegPvvvvssdGasR
TGCVVALEFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMI
.| .|.. . ..... .||. | . ||..| | ... .| || |.
sGvylaidanlelvekeeevdvFeavktlrrsRpqLvenveeYkyiYdvll
|
|||||||||
0049260 | (Phosphotyrosine protein) phosphatases II | 131-326 | 9.9e-35 | 114.8 | In-house | 3-143 (152) | alignment | ||
Range on Protein: 131-326
Range on HMM: 3-143/152.0
KTNYLRNTFICTQGPLQHTIIDFWRMIFQERAESILMLCKTMEEGRPKCVGYWpslgvtetygcirvtnmgessdefeicnlavtfvpdnvpvdeqpanl
. . . ||.||||. .|. |||||. . . |.||.. .| |..|| |.
dgyampfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi...............................................
kelrvnLIKWPNWPDRGVPDEKCHTVPQRLL----AQVRHGPCVVHCSAGIGRTGCVVALEFAYnkldrgLKVDFEEIITELRKQRAQCIQTEIQYLYIH
... .||| |||| . |. |. ..||..||||||.||||..||. . |.|..||.. .|..| . .... |. ...
......qylhlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpgqlrfly
|
|||||||||
subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 87-328 | 3.9e-34 | 112.7 | In-house | 37-231 (392) | alignment | ||
Range on Protein: 87-328
Range on HMM: 37-231/392.0
LTFEAFKQNMHKNRYSDVVCRDTTRVKL-TIDKSRYEDYIHANYVKTNYLRNTFICTQGPLQHTIIDFWRMIFQERAESILMLCKTMEEGrpkcvgywps
| . |..|||| ... |..|||| || . .||. | |... ...|..||| .. |||||.|||.. .| |. | |
qtvaqkeinlkknryknilpydsarvkleviddipdsdylnasyipsfdnekayiasqgpnaaslddfwrmvfqenvttiamvtklkegd..........
lgvtetygcirvtnmgessdefeicnlavtfvpdnvpvdeqpaN-LKELRVNLIKWPNWPDRGVPDEKCHTVPQRLLAQVRHG----PCVVHCSAGIGRT
. . | .. .|||..|| . . .. .| | ..|||||.|||
...........................................kgddartvaqfhftewPdkdvpkhtssllkfikevkadfGqythpliihcsagvgrt
GCVVALEFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRV
| |.... . . || ...|..|..| .||. || .|.
gvvisidsvvahakktrmvdvfnfvtnirrkrpymvqtkeqyafiyga
|
|||||||||
subfamily_PTPRN_pd | Subfamily PTPRN | 73-326 | 1.2e-32 | 107.8 | In-house | 32-285 (297) | alignment | ||
Range on Protein: 73-326
Range on HMM: 32-285/297.0
AKQYRKLDAQQDSSLTF--EAFKQNMHKNRYSDVVCRDTTRVKLTIDKSR-YEDYIHANYVKTNYLRN-TFICTQGPLQHTIIDFWRMIFQERAESILML
.|.. | | . | ..|..|||...|. | .||||. . |. .||| | . . |. ..| ||||| .|. |||.|.... . |..|
ekewealcayeaepstkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplastvadfwqmvweqGvvvivnl
CKTMEEGRPKCVGYWPSLGvTETYGCIRVTNMGES--SDEFeicnLAVTFVPDNVPVDEQPAnlkelrVNLIKWPNWPDRGVPDEKCHTVPQRL-LA---
.. ||| .| ||| | .|.|. | . | .|.. | .| |. .| . | .. ||..||| . . | .
trleeegvkqckrywpdeG.sevyhiyevhlvsehiwcddy....lvrsfylknlqtsetrt......vtqfhflswpeegvPasaksllefrrkvnksy
QVRHGPCVVHCSAGIGRTGCVVALEFAYNKLDRGLK-VDFEEIITELRKQRAQCIQTEIQYLYIH
. | | |||||.| ||||. ..... |.| .|.| .| . || ||.. ..|. |. ..
rGrscpivvhcsdGaGrtGvyilidlvlnrllkGvkeidiaatlehlrdqrpglvktkdqfefal
|
|||||||||
subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 94-329 | 2.6e-32 | 106.9 | In-house | 7-237 (239) | alignment | ||
Range on Protein: 94-329
Range on HMM: 7-237/239.0
QNMHKNRYSDVVCRDTTRVKLT-IDKSRYEDYIHANYVKTN-YLRNTFICTQGPLQHTIIDFWRMIFQERAESILMLCKTMEEGRPKCVGYWPSlgVTET
| ||||...| | .|| | . . . ||| |.|.. ...|.||| .. . |||||..||| |.|| .| . || ||| |
vnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpd..stsk
YGCIRVTNMgesSDEFEICNLAVTFVPDNVpvdeqpANLKELRVNLIKWPNWPDRGVPDEKCHTVPQR--LLAQVR--HGPCVVHCSAGIGRTGCVVALE
| .||| | . ||| .| . .| | .. |||.|||. . | . . | |.|||||.||||... ..
ycnlrvtlr...ktevfadyiirtfvmsqv......gqteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvid
FAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVM
. . || . . .|..| . .|| ||..|| .
amlrqakkqktvdifnyvkairedrphmvqtseqyvfihlav
|
|||||||||
subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 94-329 | 2.8e-32 | 106.8 | In-house | 6-236 (239) | alignment | ||
Range on Protein: 94-329
Range on HMM: 6-236/239.0
QNMHKNRYSDVVCRDTTRVKLT-IDKSRYEDYIHANYVKTN-YLRNTFICTQGPLQHTIIDFWRMIFQERAESILMLCKTMEEGRPKCVGYWPSlgVTET
| ||||...| | .|| | . . . ||| |.|.. ...|.||| .. . |||||..||| |.|| .| . || ||| |
vnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpd..stsk
YGCIRVTNMgesSDEFEICNLAVTFVPDNVpvdeqpANLKELRVNLIKWPNWPDRGVPDEKCHTVPQR--LLAQVR--HGPCVVHCSAGIGRTGCVVALE
| .||| | . ||| .| . .| | .. |||.|||. . | . . | |.|||||.||||... ..
ycnlrvtlr...ktevfadyiirtfvmsqv......gqteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvid
FAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVM
. . || . . .|..| . .|| ||..|| .
amlrqakkqktvdifnyvkairedrphmvqtseqyvfihlav
|
|||||||||
0051082 | (Phosphotyrosine protein) phosphatases II | 121-328 | 5.6e-31 | 102.5 | In-house | 2-148 (151) | alignment | ||
Range on Protein: 121-328
Range on HMM: 2-148/151.0
YEDYIHANYVKTNylrntFICTQGPLQhtiiDFWRMIFQERAESILMLCKTMEEGrpKCVGYWPSLGvtetygcirvtnmgessdefeicnlavtfvpdn
..|||...|| . .....|||. ||.... .. .|..|....| | .| |.|.||
lsdyinfsyvtgg.....lyrsggpla....dflellkelgiktivnlrseeerg..ycpeylpelg.................................
vpvdeqpanlkeLRVNLIKWPNWPDRGVPD--EKCHTVPQRLLAqVRHGPCVVHCSAGIGRTGCVVALEFAYNKldrglkVDFEEIITELRKQRAQCIQT
..| | ...||| |.|. . . . . ||. ..||..||||||.||||..||| . . |..||.. |.|..| ..|.
............ievlhipildwpdpglplsfdavleflellld.kkngpvlvHCsaGkgRTGtlvalylmllg......vsleealeeyrlkrpgvvqp
EIQYLYIHRV
. |.|.....
nqqflfqlfa
|
|||||||||
subfamily_ptpA1_pd | Subfamily ptpA1 | 69-298 | 7e-31 | 102.4 | In-house | 20-261 (418) | alignment | ||
Range on Protein: 69-298
Range on HMM: 20-261/418.0
IEGLAKQYRKLDAQQDSSLTFEAF-KQNMHKNRYSDVVCRDTTRVKLT-IDKSRYEDYIHANYVKTNYLRnTFICTQGPLQHTIIDFWRMIFQERAESIL
| . ...| |. | | | |.| ||||.... . |||.| |. ||| |||. | . |||||||| || |||||....|. |.
ihkikeefrlleesvgpsetsegdkkhntsknrytnilpvnhtrvqlkkiqdkegsdyinanyidgaypk.qfictqgplpntiadfwrmvwenrcriiv
MLCKTMEEGRPKCVGYWPSLGVTETYGCIRVTNmgESSDEFEICNLAVTFVPDNVPVDEQ--PANLKELR-VNLIKWPNWPDRGVPDEK------CHTVP
|| . |. | || ||| | . | | . . . | |. . . . | | . .. |||. .|| |..
mlsresencrikcdrywpeqiggeqfsiygngn..evfgtysvelveviqdpereiitrnirltfegetrditqyqyegwpdhnipdhtqpfrqllhsit
QR----LLAQVRHGPCVVHCSAGIGRTGCVVALEFAYNKLDRGLK
.| . . | | .||||||.|||| ... .|||. .|
nrqnqiipssdrnvpiivhcsagvgrtgtfctavimmkkldhyfk
|
|||||||||
subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 51-336 | 8e-31 | 101.6 | In-house | 8-288 (302) | alignment | ||
Range on Protein: 51-336
Range on HMM: 8-288/302.0
RKYVETLNNFIIaTEKLGIEGLAKQYRKLDAQQDSSLTFEAFKQNMHKNRYSDVVCRDTTRVKLTIDKsryEDYIHANYVKTNYLRNTFICTQGPLQHTI
.|.|| .. . ...| . |.. |.|... . .|||.|..||. || . |...|||. . ..|..| |. |... | .| | . .
ekWveeeeakkl.vksldtaevkkefkkidtmkvdlekCkafkknlkknqsedvpildsnlvkleaep...dsyvnaskvevPeltrsiilaQlpkvdse
---IDFWRMIFQERAESILMLCKTMEEGRpKCVGYWP-SLGVTETYGCIRVTNMGESSDEFEICNLAVTFVPDNVpvdeqpANLKELRVNLIKwpNWPDR
.||||.|||. |. .| .. | . ..| | ..|| ..| | .. | | .... .|... .| |.... ||..
dsveeFWrmvfqekivsvvilvgeeelkk.tlselfpkksgdykeygkmfvNnrkVekaeeektryviEvlPegc......snsvlanvyvlt..nWkqk
GVPDEKCHTVPQRLLA----QVRHGPCVVHCSAGIGRTGCVVALEFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMIAFARGE
||.. ... . . ..|. |.|| | ...| | .||..| .. .||.. .|.||.. ... .|| ...... . . .
kvpvkyaeliktaakvfakkikadentvivSknGaGRagafltlavaveklqkgkepnikeivksiRsqRpravdslkQyvslyialllyikkk
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 80-251 | 4.3e-29 | 96.3 | In-house | 18-182 (297) | alignment | ||
Range on Protein: 80-251
Range on HMM: 18-182/297.0
DAQQDSSLTFEAFKQNMHKNRYSDVVCRDTTRVKLTIDkSRYEDYIHANYVKTN--YLRNTFICTQGPLQHTIIDFWRMIFQERAESILMLCKTMEEGRP
| .. |.. . ..|||| |.. |.||||| .||| |.|| .|..||||. |. |||...... | |..| |.||
deargesfssakrnsslrknryrdilatddtrvkllrv.iterdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrd
KCVGYWPSL-GVTETYGCIRVTNMGESSDEFEICNLavTFVP--DNvpvdeqpanLKELRVNLIKWPNWPDRGVPDE
||. |||| . . | . | . . ||||. | | . .. |. ... .||| ||| .
kcapywpsvvqerlkagdvvveflsstsdefdrvil..telqliyr.........sesrvvrhvqflswpdhGvpsd
|
|||||||||
subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 94-341 | 2.6e-28 | 94.0 | In-house | 18-257 (290) | alignment | ||
Range on Protein: 94-341
Range on HMM: 18-257/290.0
QNMHKNRYSDVVCrDTTRVKLTIDKSRYE-DYIHANYVKT-NYLRntFICTQGPLQHT-------IIDFWRMIFQERAESILMLCKTMEEGRP----KCV
.. ..|.. . ||| | ..|. ||||||.|. | || .| || |.... | .|| |. ||..... |||. .|. . |
khemdqRlevpLv.eatrvvLkgygkrfnddyiHAnrvtcpnglr..liltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCa
GYWPS-LGVTETYG--CIRVTNMgESSDEFEICNLAVTFvpdnvpvdeqpANLKELRVNLIKWPNWPDRGVPDEKCHTVPQRLLAQVRHGPCVVHCSAGI
| | | ... .. ... | |..|. .| |.| . .|. |. . .| .. |.... . . .. | .||| ||
kYvpesvgeelkfkgltvkCksk.ekeddvetRelvvkf...........ddeeeftvtHsllkgWnklnvqedtktllsliqkvkasktpvivHcvdGi
GRTGCVVALEFAYNKLD-RGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMIafargetdvsE
| .. |.. .| |. .| .|... .||||||..|...... .. ...
SrsAalaaiilgyQkiaetsgsvkledvlkalrkqralaitsalelafvdagiv..........l
|
|||||||||
PTPc_DSPc_SM00012 | 235-330 | 1.4e-27 | 91.3 | In-house | 2-104 (105) | alignment | |||
Range on Protein: 235-330
Range on HMM: 2-104/105.0
VNLIKWPNWPDRGVPDEKchTVPQRLLAQVRH--------GPCVVHCSAGIGRTGCVVALEFAYNKLDRG-LKVDFEEIITELRKQRAQCIQTEIQYLYI
|. .....||| |||.| . .||..|.. .|.|||||||.||||..|||. ....|... .||...|. ||||||....||| |||..
vkhyhytgwpdhgvPees..dsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylfl
HRVMI
.|...
yrall
|
|||||||||
subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 90-336 | 2.8e-27 | 90.4 | In-house | 28-262 (267) | alignment | ||
Range on Protein: 90-336
Range on HMM: 28-262/267.0
EAFKQNMHKNRYSDVVCRDTTRVKLTidkSRYEDYIHANYVKTNYLRNTFICTQGPLQHTIIDFWRMIFQERAESILMLCKTMEEGRPKCvgYWPSLGVT
..| .||. |.. | ||| | . |.|| | ||.. . .|.|| ||.||. || ||. .| ... | .| |. .. .. . | .| .
siaeknqernrlddnlpyddtrvilr...tkeeeyinasyvegyktknafivtqdplkntitdfltvihdqkvpvivlltkvftdnirlf..wPPkmgqa
ETYGCIRVTNMGE-SSDEFEICNLAVTFVPDNVpVDEQPANLKELRVNLIKWPNWpdrgvpdEKCHTVPQRLLAQVRHGPCVVHCSAGIGRTGCVVALEF
. | . | | ....| | . | .. . |. .| . | . . . . | ||.||.|.||.| . ..
kkyqdltvehslekeendyqiitlelkfknesa.hnvtlyyykkwnintnnkpyl.......kplfgilaknqlengnrPlvvacsdGvGrsGtflvids
AYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMIAFARGE
... . .| . . ..|.|| ..| .|.|||... .|.|
qleraktegvsdifdflrkirsqriglvdtkeryiyihellaeyaegr
|
|||||||||
0044763 | (Phosphotyrosine protein) phosphatases II | 119-327 | 2.5e-26 | 87.8 | In-house | 15-165 (178) | alignment | ||
Range on Protein: 119-327
Range on HMM: 15-165/178.0
SRYEDYIHANYVKTNylrnTFICTQGPlqhtiIDFWRMIFQERAESILMLCKTMEEGRPKCVGYWPSLGVtetygcirvtnmgessdefeicnlavtfvp
. |||.|... . ......| |..... .. .|..|....| |..|| |||.
lersdyinaseilpg....lylgslpp.....addlellkelgithivnlteelelgflkcdpywpeeag..............................
dnvpvdeqpanlkelrvNLIKWPNWPDRGVPDEKCHTVPQRLLAQ----VRHGPCVVHCSAGIGRTGCVVALEFAYNKldrglKVDFEEIITELRKQRAq
.. ..|| |||| |. . . ..||..||||||.||.|..||. . ....||.| ..|..|
.................iqylhipipDhgvpdllehflefvefieealdekggpvlVHCsaGvgRsgtlvaaylmkkl.....glsleeaielvrerRp.
CIQTEIQYLYIHR
..... |. ....
ivpnpgqlrqLye
|
|||||||||
subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 74-327 | 4.8e-21 | 69.7 | In-house | 26-273 (303) | alignment | ||
Range on Protein: 74-327
Range on HMM: 26-273/303.0
KQYRKLDAQQDSSLTFEAFKQNMHKNRYSDVVCRDTTRVKLTiDKSryedYIHANYVKTNYLRNTfICTQGPLQHTIIDFWRMIFQERAESILMLCKTME
... |. . |.. . | .||.|||. ||.| | ..|||. | | ||||.|.. . ... | || ||.|| |||.|| ... .|.| |
nefekvvsylppsvsknqfvknmdknrfvdvicldhskvkls.dss....yihasyleldsskka.iltqlplshtaadfwqmiieqkvkcvlllltdse
EGRpkcVGYwpSLGVTETYGCIRVTNMGESSDEFEICNLAVTFVPDNVPVDEqpANLKELrVNLIKWPNWPDRGVPDE-KCHTVPQ-----RLLAQV-RH
. .| . .. . || .|. .| . | . . | . . . .. .|| .| . . | | .| .
ydk...lgg..dsvfprnqdflkfeersirvgefkrvelgdgwvlkvlsvsn..gdyksf.lhvhhykawphnsipsdgspkfvkqiwqlqsvlrkysds
GPCVVHCSAGIGRTGCVVALEFAYNKLDRG-LKVDFEEIITELRKQRAQCIQTEIQYLYIHR
| | .| ||.| .| |. | .|. . .|. | ...| |. ...
tptvymslsgcgragtfalfetahlslhseqasldlvkclenvrngrlhavqnlsqfsvvyt
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 94-222 | 6.8e-21 | 69.4 | In-house | 46-187 (350) | alignment | ||
Range on Protein: 94-222
Range on HMM: 46-187/350.0
QNMHKNRYSDVVCRDTTRVKLT--------IDKS-RYEDYIHANYVKTN----YLRNTF--ICTQGPLQHTIIDFWRMIFQERAESILMLCKTMEEGRPK
. . ||||.... . .|||| ...| . .||| |||.| . | | ||.||. |. ||...|.. . ||.| . .| .. |
elfaknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlek
CVGYWPSLGVTETygCIRVTNMGESSDEFEICNLAVTFVPDNVP
| ||. ... . ...... |. . . . | .. | . .
cyrYWqegsyddi..tvklaskwenimgindsslysadvkkeas
|
|||||||||
0048076 | (Phosphotyrosine protein) phosphatases II | 202-328 | 5.9e-20 | 66.9 | In-house | 18-138 (145) | alignment | ||
Range on Protein: 202-328
Range on HMM: 18-138/145.0
ESSDEFEICNLAVTFVPDNvpvdEQPANLKELRVNLIKWPNWPDRGVPDE--KCHTVPQRLLAQVR-HGPCVVHCSAGIGRTGCVVALEFAYNkldrgLK
.| ....| .| | . .| | . . . .|||.|||| .. . . . .. .||..||||||.||||..||. . |.
taldlellkdlgittvlnl....tselellerlgiqylylpwpDhgvpdllellleflefieealkeggpvlVHCsaGvgRtgtlvaaylmll.....lg
VDFEEIITELRKQRAQCIQTEIQYLYIHRV
|..||.. ..|.|| ...... |. .....
vsleealelvrsqrpgavpnpgqlrflyef
|
|||||||||
0048179 | (Phosphotyrosine protein) phosphatases II | 198-327 | 1.3e-19 | 65.8 | In-house | 14-139 (144) | alignment | ||
Range on Protein: 198-327
Range on HMM: 14-139/144.0
TNMGESSDEFEICNLAVTFVPDNVPvdEQPANLKELRVNLIKWPNWPDRGVPDEKCHTVPQ-----RLLAqvRHGPCVVHCSAGIGRTGCVVALEFAYnk
.. ..| ....| .| | . .. | . . | . . . .|||.|||| . ..|. ..||..||||||.||||..||. .
gslptaldlellkklgittvinlte..eyepefleregiqylhlpwpDhgvpdllellleflefieeale..eggpvlVHCsaGvgRtgtlvaaylmk..
ldrGLKVDFEEIITELRKQRAQCIQTEIQYLYIHR
|....||.. ..|..| ...... |. ....
...klglsleealalvrsrrpgavpnpgqlrfLle
|
|||||||||
subfamily_PTPN9_pd | Subfamily PTPN9 | 261-335 | 5.1e-19 | 63.4 | In-house | 218-292 (297) | alignment | ||
Range on Protein: 261-335
Range on HMM: 218-292/297.0
LAQVRHGPCVVHCSAGIGRTGCVVALEFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMIAFARG
... | |||||||||||| ..|... ..|.. .|| | . ||.||| |||. || . . .. .|
kghpsgPPivvhcsaGiGrtGtfitldiclsrleevgtvdvvetvkllrtqrafsiqtpeqyefcylavleyale
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 96-254 | 4.2e-18 | 60.1 | In-house | 29-182 (319) | alignment | ||
Range on Protein: 96-254
Range on HMM: 29-182/319.0
MHKNRYSDVVCRDTTRVKLT-IDKSRYEDYIHANYVKTN-YLRNTFICTQGPLQHTIIDFWRMIFQERAESILMLCKTMEEGRPKCVGYWPS---LGVTE
|.|. .|| ||| | | . . |..|.||. .| .|..| .|. . ||||.... .. |. |.. | | .| |.|. | |.
kdksrvinvvPlPetrvvlqrigdddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlselGikvcaeylPtketldnts
TYGCIRVTNM-GESSDEFEICNLAVTfvpdNVpvDEQpanlkELRVNLIKWPNWPDRGVPDEKCH
.|| |.|| .|. |.. | | . .| |.. | | | .|.. .|| |.
lyGdilvtlkgrevkdryaistlllk....rv..dke.....esrelthywykwleaevPaeeaa
|
|||||||||
subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 126-333 | 1.6e-17 | 58.4 | In-house | 39-221 (255) | alignment | ||
Range on Protein: 126-333
Range on HMM: 39-221/255.0
HanyvktnylrntfictqgplqhTIIDFWRMIFQERAESILMLCKTMEEGRPKCVGYWPslgvTETYGCIRVTNMGESSDEfE-----ICNLAVTFvpdN
|. |...| | ..| . ||| |||. || |.| .| . ..... .. . . | .| .
l......................tvdkfyqtivqtktevvvmlcdfaeegvekcssyfp....lekdeklkladvnvtttk.ssadvvlrtleits...t
vpVDEqpaNLKELRVNLIKWPNWPDRGVPDEKcHTVpQRLLAQVRH-GPCVVHCSAGIGRTGCVVALEFAYNKLDRGL------KVDFEEIITELRKQRA
. | | |. .. |... |.. . . . .| ||. . |||||.||||. | |..| |. | | ..|. ....|||..|.
..lge...kkkthtvkhysykGWieknaPela.rei.lnilkvvrdsksvvvhCstGiGrsaafvlaelvyqkmirsldttetveldylslleelrskrk
QCIQTEIQYLYIHRVMIAFA
. |.| .| . ... .
raihtPlqlafsilmvldlv
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 261-334 | 2.5e-17 | 57.5 | In-house | 242-316 (319) | alignment | ||
Range on Protein: 261-334
Range on HMM: 242-316/319.0
LAQVRHGPCVVHCSAGIGRTGCVVALEFAYNKLDRG-LKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMIAFAR
. ..|| ||||| |.|||| |.| ..| ..|. || ... .|..||. ..| || .|..|. .|.
gtresqGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefiykvlseyak
|
|||||||||
subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 144-326 | 2.9e-17 | 57.1 | In-house | 98-281 (302) | alignment | ||
Range on Protein: 144-326
Range on HMM: 98-281/302.0
GPLQHTIIDFWRMIFQERAESILMLCKTMEEGRPKCVGYWPS-LGVTETYGCIRVT--NMGESSDEFEICNlavTFVPDNVPVDEQP-ANLKELRVNLIK
| . |. .| .| | . . ||. .|.. || |. .| . ..| |. .. . .|| . .|. .| . .. . .. |....
vpkkstlekhwalieqynvaivvqlcsfvedeekkcaeyysdkvggelkfgrytvktvsvktdleeftdkk...sfklytveiknekkkkkvkktvdila
WPNWPDRGVPDEKCHTVPQRLLAQVRHGPCVVHCSAGIGRTGCVVALEFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIH
. ||| | |.| ... . .||||||.|||| .||. . . . |. .|.. .|. | .|.| | .|.
fsawpdhGapkeaytaldilkfcesykknvlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqdeqqliyll
|
|||||||||
subfamily_hpo-7_pd | Subfamily hpo-7 | 126-333 | 1.8e-15 | 51.6 | In-house | 42-232 (263) | alignment | ||
Range on Protein: 126-333
Range on HMM: 42-232/263.0
HanyvktnylrntfictqgpLQHTIIDFWRMIFQERAESILMLCKTMEEGRPKCVGYWPslgvTETYGCIRVTNMGESSDEFEICNLAVTFVPDNVpVDE
| || |...| | ..| . ||| |||. || |.| .| . ...|. .. . | | . .. ..|
l...................lvqtidkfyqtivqtktevvvmLcDfneegvekcssyfP....lekdekqklanvnvcttkvqsdvllktlellst.lge
qPANLKELRVNliKWPNWPDRGVPDEKCHTVpqRLLAQVRH-GPCVVHCSAGIGRTGCVVALEFAYNKLDRGL------KVDFEEIITELRKQRAQCIQT
...... . .. |... | . . ..| .|. . |||||.||||. . |..| |. | | ..|. ....|||..|.. |.|
.Kkkthtvkhy..sykgWiekndpelareil..nilkvarnskslvvhcstGiGrsaafsvaElvyqkmirsldttstveldylsLleelrssrkraiht
EIQYLYIH-----RVMIAFA
.| . |. .||
PmqLafsilmvLdfvlnnfa
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 264-330 | 2.1e-13 | 44.8 | In-house | 226-292 (297) | alignment | ||
Range on Protein: 264-330
Range on HMM: 226-292/297.0
VRHGPCVVHCSAGIGRTGCVVALEFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMI
| . .||||||.||.| || . .|| .. | |.. ||.|||. .|| |. ... ...
prnayllvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqtleqfellydavl
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 236-341 | 3.5e-13 | 43.7 | In-house | 92-203 (440) | alignment | ||
Range on Protein: 236-341
Range on HMM: 92-203/440.0
NLIKWPNWPDRGVPDEKCHTVP-----QRLLAQVRHGPCVVHCSAGIGRTGCVVALEFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMI
. .. |||.||| . . .. || .|||||| |||| ..|.. . | ..| .| .|..| | .|| || ..| ...
kqyhyqgwpdkgvpkfagpvlkmiqdvnesqekagngpllvhcsagagrtgviiavdsilreakrsdqidifsfinsmrnnrpqmvqtpeqyafvheavl
-AFARGETDVSE
.. |.| . |
egllcgdtlile
|
|||||||||
subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 80-167 | 9.8e-13 | 42.3 | In-house | 22-115 (347) | alignment | ||
Range on Protein: 80-167
Range on HMM: 22-115/347.0
DAQQDSSLTFEAFKQNMHKNRYSDVVCRDTTRVKLTIDKSRY------EDYIHANYVKTNYLRNTFICTQGPLQHTIIDFWRMIFQERAESILM
. | .|. ..... ||| || |.||| |. .||. | || | ..| . .. .| || || .|. |||.|.. . ..
anyspskftsvewekslsknrskdvklidatrvvlspeksknsraddvetyinashikfdnaskeyiltqyplpdtvrdfwkmvsvtkvtqvvt
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 102-221 | 1.8e-12 | 41.3 | In-house | 55-189 (349) | alignment | ||
Range on Protein: 102-221
Range on HMM: 55-189/349.0
SDVVCRDTTRVKL---------------TIDKSRYEDYIHANYVKTNYLR--NTFICTQGPLQHTIIDFWRMIFQERAESILMLCKTMEEGRPKCVGYWP
.|.. . .|||| . | .. .||| |||.| . . .|.|| || |. ||...| .. . .| | . |.. || ||
kdilPyehsrvklkkslksskvikastsesdsgklddyinanylkltrisvekkyiatqaPlPstvddfykvillngvklvlsLnddkelslekcdiywq
SLGVTETygCIRVTNMGESSDEFEICNLAVTFVPDNV
| .. ... | . . . . . | | | |.
elsysni..tvklqnsslyianvqGnslrvstvkdtd
|
|||||||||
subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 138-327 | 5.9e-12 | 40.2 | In-house | 6-198 (199) | alignment | ||
Range on Protein: 138-327
Range on HMM: 6-198/199.0
TFICTQGPLQHTIIDFWRMIFQERAESILMLCKTMEEGRPKCVGYWPSLG-VTETYGCIRVTNMGE-SSDEFEICNLAVTfvpDNVpvdEQPANLKELrv
.|.|| ||..|. |||.|... . |.|. . |||. | ||.. || . .. |. | .| .|. | .|.
ryiatqhplretmadfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitalilt...nnt...tappstrei..
NLIKWPNWPDRGVPDEK---CHTVPQRLL----AQVRHGPCVVHCSAGIGRTGCVVALEFAYNKLD--RGLKVDFEEIITELRKQRAQCIQTEIQYLYIH
.. | .. |. | | . | . | .|||| | | || |||. . . ||. |. ||. | | . .| .|.
shyqftswkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiy
R
.
q
|
|||||||||
subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 138-327 | 5.9e-12 | 40.2 | In-house | 5-197 (198) | alignment | ||
Range on Protein: 138-327
Range on HMM: 5-197/198.0
TFICTQGPLQHTIIDFWRMIFQERAESILMLCKTMEEGRPKCVGYWPSLG-VTETYGCIRVTNMGE-SSDEFEICNLAVTfvpDNVpvdEQPANLKELrv
.|.|| ||..|. |||.|... . |.|. . |||. | ||.. || . .. |. | .| .|. | .|.
ryiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitalilt...nnt...tappstrei..
NLIKWPNWPDRGVPDEK---CHTVPQRLL----AQVRHGPCVVHCSAGIGRTGCVVALEFAYNKLD--RGLKVDFEEIITELRKQRAQCIQTEIQYLYIH
.. | .. |. | | . | . | .|||| | | || |||. . . ||. |. ||. | | . .| .|.
shyqftswkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiy
R
.
q
|
|||||||||
subfamily_eak_pd | Subfamily eak | 78-198 | 7e-12 | 39.4 | In-house | 34-155 (332) | alignment | ||
Range on Protein: 78-198
Range on HMM: 34-155/332.0
KLDAQQD-SSLTFEAFKQNMHKNrYSDVVCRDTTRVKLTIDKSRYEDYIHANYVKTNYLRNTFICTQGPLQHTIIDFWRMIFQERAESILMLCKTMEEGR
.|| .| | . | .....| ..| .| |.|| . . || | .. . . . .| | . . . ||.|...... .|..| . .|..
dlddyqrllsisetarleavnrn.vvkivpydrylvrltssqlnrlGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledvelkl
PKCVGYWPSLG-VTETYGCIRVT
| |.| . .| . |.
eksdkyfpdktreelkfGildve
|
|||||||||
PTEN_1 | 200-324 | 1e-10 | 36.7 | In-house | 62-184 (196) | alignment | |||
Range on Protein: 200-324
Range on HMM: 62-184/196.0
MGESSDEFEICNLAVTFVPdnvpvDEQPANLKELRVNLIK--WPNWPDRGVPDEKCHTVPQRLLAQV-R----HGPCVVHCSAGIGRTGCVVALEFAYNK
. .... . ..||. . ... .|.| . . .. ..| |.|. .. . ... . .. ..||| ||.||.|.||| | .
nlkedgitlvvnlseeeel.....sgrsydleeffksgveylhfpieDhgapslselfdicksfiewllsdpngnvVlVHCkaGlgRsGtvvaayLmykg
LdrglkVDFEEIITELRKQR-AQCIQTEIQYLY
...| . .|..| . .... | .
k.....ltadeAlelvrekRppgapnspsqerl
|
|||||||||
subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 84-198 | 2.4e-10 | 34.5 | In-house | 84-194 (244) | alignment | ||
Range on Protein: 84-198
Range on HMM: 84-194/244.0
DSSLTFEAFKQ-NMHKNRYSDVVCRDTTRVKLTiDKSRYEDYIHANYVKTNYLRNTFICTQGPLQHTIIDFWRMIFqERAESILMLCKTMEEGRpkcvGY
| |. .||. | .||| . . | || |. | . || | .| .| || || | .|||.|.. || .|.. ..|| |
dpsvmkdafnpnnswknregaglpfdfnrvpls.kgsmgntyinasfvgclgrtaeyiltqhpladtsmdfwkmml.erhvnvlvvlgsveeed....ey
WPSLGVTETYGC-IRVT
|| | | | ||
wpdseplewyeeditvt
|
|||||||||
subfamily_Cele-PTP-12_pd | Subfamily Cele-PTP-12 | 87-175 | 5.1e-10 | 33.3 | In-house | 26-113 (332) | alignment | ||
Range on Protein: 87-175
Range on HMM: 26-113/332.0
LTFEAFKQNMHKNRYSDVVCRDTTRVKLTIDKSRyEDYIHANYVKTNYLRNTFICTQGPL-QHTIIDFWRMIFqERAESILMLCKTMEEG
|.. | .|| || . | | .||.|. . . .|. |..| ....| .| |. .|| ||||. || |.... ..|
ntydkflnnmdmnriphlycfdhsrvelapqdgk.ddfynaswvdgyskksayifaqapfndhteyvfwrmvs.erkpsmilvfgdidek
|
|||||||||
subfamily_PTPDC1_pd | Subfamily PTPDC1 | 261-326 | 9.1e-10 | 33.3 | In-house | 109-169 (182) | alignment | ||
Range on Protein: 261-326
Range on HMM: 109-169/182.0
LAQVRHGPCVVHCSAGIGRTGCVVALEFAYNKldrglKVDFEEIITELRKQRAQCIQTEIQYLYIH
...| ||| || |||| ..| . |.| ... |. |. .|..|...||| | ..
afalqegkvavhChaGlGrtGvliacylvyak.....rltaekaiklvrskrpksiqtreqvelvk
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 136-201 | 1.2e-09 | 32.0 | In-house | 235-297 (440) | alignment | ||
Range on Protein: 136-201
Range on HMM: 235-297/440.0
RNTFICTQGPLQHTIIDFWRMIFQERAESILMLCKTMEEgrpKCVGYWPSLGVTETYGCIRVTNMG
.|.||.|| ||. |..||||.. . | .|.|| . . | ||| . |.| . | |
knafiatqmpldstvldfwrlvhdyristiimlnqlndk...tcsiywpvntrsvtfgpftvghkg
|
|||||||||
subfamily_Sponge-PTP-7_pd | Subfamily Sponge-PTP-7 | 270-330 | 7.6e-09 | 29.9 | In-house | 2-62 (69) | alignment | ||
Range on Protein: 270-330
Range on HMM: 2-62/69.0
VVHCSAGIGRTGCVVALEFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMI
|||||.| |||| .|. .. || . . .|| | . ||.|..|| ..
vvhcssgtgrtgtfiaimvemarikseklvdifnnvqymrkcrpmmvmneieyifihdalv
|
|||||||||
0038934 | (Phosphotyrosine protein) phosphatases II | 230-322 | 9.7e-09 | 30.6 | In-house | 75-166 (194) | alignment | ||
Range on Protein: 230-322
Range on HMM: 75-166/194.0
LKELRVNLIKWPN-----WPDRGVPDEKCHTVPQRLlAQVRHGPCVVHCSAGIGRTGCVVALEFAYNkldrgLKVDFEEIITELRKQRAQCIQTEIQY
.... . .|.| |. . .. .. | . | .. .| ..||| ||.||||..|| | |. . || | .| | .|.. ..
fekagieylklpfpddgtvPsleillrfldlvdefl.nedpggvvaVHCkaGlgRtGtlvaaYLiyr.....lgmsaeeAialfrekRpgaipnqdyl
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 264-332 | 1.4e-08 | 28.8 | In-house | 260-343 (350) | alignment | ||
Range on Protein: 264-332
Range on HMM: 260-343/350.0
VRHGPCVVHCSAGIGRTGCVVALEFAYN-------------KLDRGLKV--DFEEIITELRKQRAQCIQTEIQYLYIHRVMIAF
| | .||||||.|||| .|.|.. . |||. |. . |. |||||| . .|. |...|. . .
arsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlisiivnelrkqrismvqnldqfifiYeallfy
|
|||||||||
subfamily_Sponge-PTP7_pd | Subfamily Sponge-PTP7 | 270-329 | 1.3e-07 | 25.8 | In-house | 1-60 (69) | alignment | ||
Range on Protein: 270-329
Range on HMM: 1-60/69.0
VVHCSAGIGRTGCVVALEFAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVM
|||||.| |||| .|. .. || . . .|| | . | .|..|| .
vvhcssGtGrtGtfiaimvemarikseklvdifnnvqymrkcrpmmvmneneymfihdal
|
|||||||||
subfamily_Sponge-PTP3_pd | Subfamily Sponge-PTP3 | 81-144 | 2.6e-07 | 24.7 | In-house | 34-95 (95) | alignment | ||
Range on Protein: 81-144
Range on HMM: 34-95/95.0
AQQDSSLTFEAFKQNMHKNRYSDVVCRDTTRVKLTIDksRYEDYIHANYVKTNYLRNTFICTQG
.. | . . |. |||. ... |.||| || | ||| | .| .| .|..||
mtsgapytvgsseanipknrflnifpydatrvvlttk..rdsdyinacfvdgyarkncyiaaqg
|
|||||||||
subfamily_Sponge-PTP-4_pd | Subfamily Sponge-PTP-4 | 116-208 | 3.2e-07 | 24.7 | In-house | 7-93 (130) | alignment | ||
Range on Protein: 116-208
Range on HMM: 7-93/130.0
IDKSRYEDYIHANYVKTNYLRNTFICTQGPLQHTIIDFWRMIFqERAESILMLCKTMEEGRpkcvGYWPSLGVTETYGCiRVTNMGESSDEFE
... . ..||.|..| . .. || || | .|||.|.. || .|.. ..|| ||| | | ... |||.
vsrlqgntyinasfvGllgrtaeylltqhpladtsmdfwkmml.eryvnvlvvlgsveeed....eywpdsePlewyee.diivtltdrdefk
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 265-332 | 2.3e-06 | 21.2 | In-house | 264-343 (349) | alignment | ||
Range on Protein: 265-332
Range on HMM: 264-343/349.0
RHGPCVVHCSAGIGRTGCVVALEFAYN----------KLDR-GLKVDF-EEIITELRKQRAQCIQTEIQYLYIHRVMIAF
. . .|||||| |||| .| |.. . |.. |. | |. |||||| . .| |. |. .. .
qlstllvhcsaGcGrtGvlvtldlllsileplqnesnkiklqallkDlisiivnelrkqrismvqnlaqfiaiyealLky
|
|||||||||
subfamily_Cele-PTP-3_pd | Subfamily Cele-PTP-3 | 79-174 | 4.4e-06 | 18.4 | In-house | 13-101 (275) | alignment | ||
Range on Protein: 79-174
Range on HMM: 13-101/275.0
LDAQQDSSLTFEAFKQNMHKNRYSDVVCRDTtrvklTIDKSRYEDYIHANYVKTNYlrNTFICTQGPLQHTIIDFWRMIFQERAESILMLCKTMEE
|| . | | .| .|||...|.| | .|. | ..||| ..| | |. .| | . | |. .... .... | |
lddlnlddekierfirngeknrftnvtcfde.....ildrenqeffvhantfrtpy..gnflisqapndstnadhlhllwiynvqtvvclvlpeea
|
|||||||||
TetR_C_9 | Transcriptional regulator, TetR, C-terminal | 307-352 | 8.2e-06 | 13.1 | Pfam-A | 7-50 (129) | alignment | ||
Range on Protein: 307-352
Range on HMM: 7-50/129.0
ELRKQRAQCIQTEIQYLYIHRVMIAFARGETDVSEKALAaaDAFLK
||. ...|.| .| |..|...| | ... . .| | .|.
klrrhlskvidtyfkyPylnrllaalvrdsdeeearria..dkyle
|