Synonym: CELE_Y54F10BM.3, Y54F10BM.3
Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
| Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
|---|---|---|---|---|---|---|---|---|---|
| 0036941 | (Phosphotyrosine protein) phosphatases II | 407-686 | 5.8e-52 | 172.2 | In-house | 9-281 (297) | alignment | ||
Range on Protein: 407-686
Range on HMM: 9-281/297.0
DPSKTVIANWFEWCQPEFEIPIELTAMSAGNPKLCRDPKVQAWDSTSYLVDDTH--FIHASTVtaPGKEYIGKAIICQAPFddkekghPDTRESFWRMVW
... . .||...| . .. .|.. .| ...| . . ..|.| .|| . .|.|| | .| .. | |..|.| |.| |.||||||
llflalllkefeellpllllgslsvallpenleknRykdilpydhtRVklddegsdYinAsyv..dgydlkrkfIatqgPl.......pntvedFWrmvw
DTRATYVVMCCQIMENGVQKCGRYFPDETGATENYGFAEVQLLEKHEMLNGHLLTRKIELTSGtwkhsdDDPPIRTITHFQFLKWKEGEGLE-GEMSMDA
. . | .|| .. .|.| .|| .|.|.|.| . .|| |.||. ...|... .|..|.| .... ||.|||....| . | . .|
eqnvtvIvmltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdt......gngesrtvthfhytgwpdhgvpespaslldf
FNYVNHRTRN--NLDPIIVHSSLGTGRACAFVGAEYMFQMIN---TKKCGTARFFQVDFRTKRLGALQNGKQLFWVQNMAFELLIKKL
...|... .. . |..||.| | ||...|..|..|.|... . .. . . .|..| || |. |. .. . .||| |||
ielvrkvlkllpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallellkkkl
|
|||||||||
| 0040438 | (Phosphotyrosine protein) phosphatases II | 409-689 | 2.4e-50 | 167.0 | In-house | 16-283 (317) | alignment | ||
Range on Protein: 409-689
Range on HMM: 16-283/317.0
SKTVIANWFEWCQPEFEIpIELTAMSAGNPKLCRDPKVQAWDSTSYLVDD------THFIHASTVtaPGKEYIGKAIICQAPFddkekghPDTRESFWRM
..|.. ..||... . .|. |....| | . .|.. . . . .|.|| | .| .. | |..|.| |.| |.||||
dftalleefedllslkld.tysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyv..dgpnlkrkfIatqgPl.......pntvedFwrm
VWDTRATYVVMCCQIMENGVQKCGRYFPDetGATENYGFAEVQLLEKHEmlNGHLLTRKIELTSGtwkhsdDDPPIRTITHFQFLKWKEGEGL-EGEMSM
||. . |..|| .. .|.|..|| .|.|. | | .|| |.||. .| ... |..|.. .|.. ||.|||... | .. .
vweqgvtvivmLteleelgrekcaqYwpl..getltygdftvtllseee..lagitlrtlevedl......gdsesrtvthfhytgWpdhgvppspdlll
DAFNYVNHRTRNNLDPIIVHSSLGTGRACAFVGAEYMFQMINTKKCGTARFFQVDFRTKRLGALQNGKQLFWVQNMAFELLIKKLKMH
| ...|.. ... |..||.| | ||...|..|..|......... .. .| .| || |. |. .. ...|.| .||..
dfleavrealedpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleylkrkltle
|
|||||||||
| 0050432 | (Phosphotyrosine protein) phosphatases II | 396-687 | 3.3e-50 | 166.6 | In-house | 27-304 (308) | alignment | ||
Range on Protein: 396-687
Range on HMM: 27-304/308.0
SMCSIIPGKERDPSKTVIANWFEWCQPEFEIPIELTAMSAGNPKLCRDPKVQAWDSTSYLVD-DTHFIHASTVTAPGKEYIGKAIICQAPFddkekghPD
|. ... |. ... . .|| . .... .|. | ...| . . ..|.. .| ....|.|| |. . . . | |..|.| |.
svldllkllekaldlglleeefeellsvkplleysvallpenkdkNrykdilpydhsRVkldegsdYInAsyvdgyssklprkfIatqgPl.......pn
TRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDETG-ATENYGFAEVQLLEKHEmlNGHLLTRKIELTSGTwkhsddDPPIRTITHFQFLKWKEGE
| |.||||||. . ...|| ....|||..|| .|.|.|.| ...|| | ||. .. ... .|..||| |.. ||.|||... |...
tvedFwrmvweqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseev..lddytvrtleltnlg......dgesrtvthfhytnWpdhg
GLEG-EMSMDAFNYVNHRTRNnlDPIIVHSSLGTGRACAFVGAEYMFQMINTKKCGTARFFQVDFRTKRLGALQNGKQLFWVQNMAFELLIKKLK
. |. .| ...|... .. ||.||.| | ||...|. ............. .. .|..| |. |. |.... ...|.| .||.
vPpspeilldflelvrkslpg..gpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylflyralleylklklt
|
|||||||||
| 0039614 | (Phosphotyrosine protein) phosphatases II | 385-687 | 3.1e-48 | 160.1 | In-house | 6-294 (297) | alignment | ||
Range on Protein: 385-687
Range on HMM: 6-294/297.0
KKLFTKMSYSPSMCSIIPGKERDPSKTVIANWFEWCQPEFEiPiELTAMSAGNPKLCRDPKVQAWDSTSYLV-------DDTHFIHASTVtaPGKEY-IG
..|.. .... |.. .. ..|. |||.. ..||. . .. . .|.. | ...| . . ..|.. . |. .|.|| | .| ..
dallesipiplsvldlllllekansktllllefeellslkp.d.ysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyv..dgydlltr
KAIICQAPFDDkekghpdTRESFWRMVWDTRATYVVMCCQIMENGVqKCGRYFPDETGateNYGFAEVQLLEKHEmlNGHLLTRKIELTSgtwkhsdDDP
| |..|.| .. | |.||||||. . |..|| .. .|.|. || .|.|.|.| .|| | ||. .. ... .|..|.| ...
kfIatqgPlpe.......tvedFwrmvweqgvtvivmLtklvelgr.kcaqywpeegg...tygdftvtllkveh..ldgytvrtlevtn.......nge
PiRTITHFQFLKWKEGEGLE-GEMSMDAFNYVNHRTRN--NLDPIIVHSSLGTGRACAFVGAEYMFQMINTKKCGTARFFQVDFRTKRLGALQNGKQLFW
. ||.||||...| .. . | ......|... .. . |..||.| | ||...|..| .|......... .. .| .| || |. |. .
s.rtvthfqytgwpdhgvppslellleflelvrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrf
VQNMAFELLIKKLK
......||| .||.
lydallellkrklt
|
|||||||||
| 0047943 | (Phosphotyrosine protein) phosphatases II | 409-681 | 6.5e-48 | 158.9 | In-house | 10-271 (273) | alignment | ||
Range on Protein: 409-681
Range on HMM: 10-271/273.0
SKTVIANWFEWCQPEFEIPIELTAMSAGNPKLCRDPKVQAWDSTSYLV--DDTHFIHASTVtaPGKEYIGKAIICQAPFddkekghPDTRESFWRMVWDT
..|... ||. .. ... .|. | ...| . . ..|.. . .....|.|| | .| .. | |..|.| |.| |.||||||.
gltllleefelllslkplltysvallpenkdknrykdilpydhsrvklgdggsdyinAsyv..dgynlkrkfiatqgPl.......pntvedfwrmvweq
RATYVVMCCQIMENGVQKCGRYFPDETGA-TENYGFAEVQLLEKHEmlNGHLLTRKIELTSGTwkhsddDPPIRTITHFQFLKWKEGEGL-EGEMSMDAF
.....|| ....|.| .|| .|.|.| | ...|| | ||. .. ... .|..|||. .. ||.|||....| . |. .. .
nvrviVmLtelvelgrekcaqYwpleggelsltygkftvtllseet..kddytvrtleltnlg......tgesrtvthfhytgwpdhgvppslesllefi
NYVNHRTRN--NLDPIIVHSSLGTGRACAFVGAEYMFQMINTKKCGTARFFQVDFRTKRLGALQNGKQLFWVQNMAFEL
..|.. .. . |..||.| | ||...|. ............. .. .|..| |. |. |. .. ....|.
elvrkalealpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyealley
|
|||||||||
| 0051299 | (Phosphotyrosine protein) phosphatases II | 409-682 | 5e-47 | 156.1 | In-house | 21-286 (288) | alignment | ||
Range on Protein: 409-682
Range on HMM: 21-286/288.0
SKTVIANWFEWCQPEFEIPIELTAMSAGNPKLCRDPKVQAWDSTSYLV------DDTHFIHASTVtaPGKEYIGKAIICQAPFddkekghPDTRESFWRM
..| ... ||.... .. . .|. | . .| . . ..|.. . ... .|.|| . .| .. | |..|.| |.| |.||||
gltglleefeellsllpdltlsaallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyi..dgynlkrkfIatqgPl.......pntvedFWrm
VWDTRATYVVMCCQIMENGVQKCGRYFPDetGATENYGFAEVQLLEKHEmlNGHLLTRKIELTSGTWKHsdDDPPIRTITHFQFLKWKEGEGLE-GEMSM
||. . ...|| ....|.|..|| .|.|. | ...|| | ||. .. ... .|..|.| .. . | ||.|||....| . . |. .
vweqnvrvIvmltklvelgrekcaqYwpl..ggsltygditvtllseev..lddytvrtlevtnldlld..gdgesrtvthfhytnwpdhgvpdspelll
DAFNYVNHRTRNNLDPIIVHSSLGTGRACAFVGAEYMFQMINTKKCGTARFFQVDFRTKRLGALQNGKQLFWVQNMAFELL
| ..|.. ... |..||.| | ||...|. ............. .. . .|..| |. |. |. .| ...|.|
dflrlvrkalasgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyealleyl
|
|||||||||
| 0045450 | (Phosphotyrosine protein) phosphatases II | 411-684 | 1.3e-46 | 155.2 | In-house | 27-306 (307) | alignment | ||
Range on Protein: 411-684
Range on HMM: 27-306/307.0
TVIANWFEWCQPEFE--IPIELTAMSAGNPKLCRDPKVQAWDSTSYLV-------DDTHFIHASTVTA------PGKEYIGKAIICQAPFDDkekghpdT
| .. .||. ... . .|.. | ...| . . ..|.| . .|...|.|| |. .| | |..|.| .. |
tgllkefekllsvtvfllgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydlkrkfIatqgPlpe.......t
RESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDEtGATENYGFAEVQLLEKHEmlNGHLLTRKIELTSGtwkhsDDDPPIRTITHFQFLKWKEGEGL
|.||||.|. . |..||... .|.| .|| .|.||| | . .|| | ||.... ... |..|.| | . . ||.|||....| ..
vedFwrmlweqgvtvivmltelvelgrekcaqywPde.geeltygnftvtllseeh..ldgytvrtlevtdl.....dgtgesrtvthfhytgwpdhgvp
E-GEMSMDAFNYVNHRTRN--NLDPIIVHSSLGTGRACAFVGAEYMFQMINTKKC---GTARFFQVDFRTKRLGALQNGKQLFWVQNMAFELLIK
. |. | ...|.. .. . |..||.| | ||...|..| .| ..... .. ... .| .| || || |. .......||| |
psfeelldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeallelllk
|
|||||||||
| 0043336 | (Phosphotyrosine protein) phosphatases II | 412-681 | 7.1e-46 | 152.3 | In-house | 21-276 (278) | alignment | ||
Range on Protein: 412-681
Range on HMM: 21-276/278.0
VIANWFEWCQPEFEiPIELTAMSAGNPKLCRDPKVQAWDSTSYLVDD------THFIHASTVtaPGKEYIGKAIICQAPFDDkekghpdTRESFWRMVWD
.. . || . . . .|.. | ...| . . ..|.. ... . .|.||.| .| .. | |..|.| .. | | ||||||.
llllefeellsfkl.dtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyv..dgynvprkfiatqgPlpe.......tvedFwrmvwe
TRATYVVMCCQIMENGVQKCGRYFPdetGATENYGFAEVQLLEKHEmlNGHLLTRKIELTSgtwkhsDDDPPIRTITHFQFLKWKEGEGL-EGEMSMDAF
. | .|| .. .|.|..|| .|.| | ...|| | ||. .. ... .|..|.| |.. ||.||...|.| ... .. .|
lgvttivmLtelvelgrvkcaqYwp...ggsltygdftvtllkeeh..lddytvrtlevtn......lgdgesrtvthyhylgwpdhgvpeslsllldfl
NYVNHRTRNNLDPIIVHSSLGTGRACAFVGAEYMFQMINTKKCGTARFFQVDFRTKRLGALQNGKQLFWVQNMAFEL
..|... ... |..||.| | ||...|............ .. .. ..|..| ||.|. |. .. ....|.
kavrealedsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyealley
|
|||||||||
| 0046845 | (Phosphotyrosine protein) phosphatases II | 431-688 | 1.4e-45 | 151.2 | In-house | 22-280 (284) | alignment | ||
Range on Protein: 431-688
Range on HMM: 22-280/284.0
TAMSAGNPKLCRDPKVQAWDSTSYLV-------DDTHFIHASTVTAPGK---EYIGKAIICQAPFddkekghPDTRESFWRMVWDTRATYVVMCCQIMEN
.|. | ...| . . ..|.. . .|...|.|| |. .. . | |..|.| |.| |.||||||. .....|| ....||
vallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPl.......pntvedFwrmvweqnvrvIVmltelven
GVQKCGRYFPDEtGATENYGFAEVQLLEKHEmlNGHLLTRKIELTSGtwkhsDDDPPIRTITHFQFLKWKEGEGLE-GEMSMDAFNYVNHRTR--NNLDP
|..|| .|.|.| | . .|| | ||.... ... .|..||| . . . ||.|||....| . . | .. ...|.. . .. |
grekcaqYwple.gevltygdftvtllseev..kddytvrtleltnl.....gytgesrtvthfhytswpdhgvppspedlleflrlvrellenlpgggp
IIVHSSLGTGRACAFVGAEYMFQMINTKK---CGTARFFQVDFRTKRLGALQNGKQLFWVQNMAFELLIKKLKM
|.||.| | ||...|. ............ . .. .|..| |. |. |. .| ....|.| .||..
ivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleylklkltl
|
|||||||||
| DSPc_SM00195 | 457-681 | 6.7e-42 | 139.0 | In-house | 52-261 (263) | alignment | |||
Range on Protein: 457-681
Range on HMM: 52-261/263.0
DDTHFIHASTVTAPgkEYIGKAIICQAPFddkekghPDTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDETGATENYGFAEVQLLEKHEMLnGH
... .|.|. .. . .. | |..|.|. |.| |.||||||... ...|| .. .||| .|| ||.|.| | .|..| .|.| |.... .
egsdYINAnyikga..nkkkkyIatQgPl.......pstvedFWrmvweekvkiivmlteeeengkekcdrywpeesggketfgkisvklvevekkk.de
LLTRKIELTSGTWkhsdddPPIRTITHFQFLKWKEGEGL-EGEMSMDAFNYVNHRTRNNLDPIIVHSSLGTGRACAFVGAEYMFQMINTKKCGTARFFQV
. .|..||| . |..|..|. .|.. . . . .. ...|....... ||.||.| | ||...|| .... . ....|
iilrtleltkegk......eetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivk
DFRTKRLGALQNGKQLFWVQNMAFEL
.|..| |. |. .|. .. ... |.
elRkqRpgmvqtleqYlfiyeailey
|
|||||||||
| PTPc_SM00194 | 457-681 | 6.7e-42 | 139.0 | In-house | 52-261 (263) | alignment | |||
Range on Protein: 457-681
Range on HMM: 52-261/263.0
DDTHFIHASTVTAPgkEYIGKAIICQAPFddkekghPDTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDETGATENYGFAEVQLLEKHEMLnGH
... .|.|. .. . .. | |..|.|. |.| |.||||||... ...|| .. .||| .|| ||.|.| | .|..| .|.| |.... .
egsdYINAnyikga..nkkkkyIatQgPl.......pstvedFWrmvweekvkiivmlteeeengkekcdrywpeesggketfgkisvklvevekkk.de
LLTRKIELTSGTWkhsdddPPIRTITHFQFLKWKEGEGL-EGEMSMDAFNYVNHRTRNNLDPIIVHSSLGTGRACAFVGAEYMFQMINTKKCGTARFFQV
. .|..||| . |..|..|. .|.. . . . .. ...|....... ||.||.| | ||...|| .... . ....|
iilrtleltkegk......eetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivk
DFRTKRLGALQNGKQLFWVQNMAFEL
.|..| |. |. .|. .. ... |.
elRkqRpgmvqtleqYlfiyeailey
|
|||||||||
| 0040439 | (Phosphotyrosine protein) phosphatases II | 432-683 | 8.8e-41 | 135.5 | In-house | 6-247 (249) | alignment | ||
Range on Protein: 432-683
Range on HMM: 6-247/249.0
AMSAGNPKLCRDPKVQAWDSTSYLVDD------THFIHASTVtaPGKEYIGKAIICQAPFDDkekghpdTRESFWRMVWDTRATYVVMCCQIMENGVQKC
|. |....| | . ..|.. . . . .|.|| . .| . . |..|.| .. | |.||||.|. . |..||... .|.| .||
allpenkdknrypdilpydhsrvklsilpglflsdyinAsyi..dgyyikrrfiatqgPlpe.......tvedfwrmlwelgitvivmLtslvelgrekc
GRYFPDetGATENYGFAEVQLLEKHEmlNGHLLTRKIELTSGtwkhsdDDPPIRTITHFQFLKWKEGEGL-EGEMSMDAFNYVNHRTRN--NLDPIIVHS
.|.|. | . .|| |.||. .. .... .|..||| |.. ||..|.|...| . | .| ...|.. .. . |..||.
aqywpl..ggsleygdftvtllsvev..kddytvrtleltnl......ydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHC
SLGTGRACAFVGAEYMFQMINTKKCGTARFFQVDFRTKRLGALQNGKQLFWVQNMAFELLI
| | ||...|..| .|......... .. ..|..| || || |. .......|||
saGvgRtGtfiaaylmleqlekelgvdleeavkllrsqRpgavqnpeqyrflyeallelll
|
|||||||||
| 0042113 | (Phosphotyrosine protein) phosphatases II | 433-681 | 9.6e-41 | 135.2 | In-house | 5-242 (245) | alignment | ||
Range on Protein: 433-681
Range on HMM: 5-242/245.0
MSAGNPKLCRDPKVQAWDSTSYLVD------DTHFIHASTVtaPGKEYIGKAIICQAPFDDkekghpdTRESFWRMVWDTRATYVVMCCQIMENGVQKCG
. |....| . . ..|.| . |. .|.|| | .| .. .| |..|.| .. | | ||||.|. . |..||... .|.| .||
llpenkdknrysdilpydhtrvklspdggdldsdyinasyv..dgyritpkfiatqgPlpe.......tvedfwrmlwelgittivmLteeeelgrvkca
RYFPDetGATENYGFAEVQLLEKHEmlNGHLLTRKIELTSGtwkhsdDDPPIRTITHFQFLKWKEGEGLE-GEMSMDAFNYVNHRTR-NNLDPIIVHSSL
.|.|. | . .|| |.||. . .... .|..|.| |.. |...|...| | .. . |. |....|.. . .. |..||.|
qywpl..gesltygdftvtllseeh..lddytvrtlevtnl......gddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsa
GTGRACAFVGAEYMFQMINTKKCGTARFFQVDFRTKRLGALQNGKQLFWVQNMAFEL
| ||...|..| .|...... .. .. ..| .| || |. |. ... ...||
GvgRtGtfiaaylmleqlekelgvsleeavkelrsqRpgavqtpsqyrflyeallel
|
|||||||||
| 0045098 | (Phosphotyrosine protein) phosphatases II | 417-683 | 3.4e-40 | 133.6 | In-house | 13-273 (278) | alignment | ||
Range on Protein: 417-683
Range on HMM: 13-273/278.0
FEWCQPEFEIPIELTAMSAGNPKLCRDPKVQAWDSTSYLvdDthFIHASTVTAPgKeyiGKAIICQAPFDdkekghpDTRESFWRMVWDTRATYVVMCCQ
||. . . . ..|. || ...| . ....|.. | .|.|| .. . . | |..|.|.. .| ..||||.|. . |..||...
fefllllgipseitpalylgnldknRykdilpydhsrVk..d..YINAsyidgy.p...kkfIatqgPlp.......stvadfwrmlwelgitvivmlte
IMENGVQKCGRYFPDetGATENYGFAEVQLLEKHEMlnGHLLTRKIELTSGTWKHSDDDppIRTITHFQFLKWKEGEGLEGE---MSMDAFNYVNHRTRN
.|.|..|| .|.|. | ...|| .| ||. ... .. .|....| |....|. |..||...| | ... . . ......... ..
lvelgrekcaqywpe..ggsltygdftvtllseevl..ddytlrtllvtnltveredle..srgvthlhylpwpdhgvpslpilksflellefirealkl
-------------NLDPIIVHSSLGTGRACAFVGAEYMFQMIntKKCGTARFFQVDFRTKRLG-ALQNGKQLFWVQNMAFELLI
. |..|| | | ||....|.| .| ... .. .. .|..| | |.|| |. .. .. |||
laslllsslllldsggpvlVHCsaGvgRtGtlvaaylmlell..eggvdlleavkelrsqRpglavqnleqyrflyefllelll
|
|||||||||
| Y_phosphatase | Protein-tyrosine phosphatase | 437-677 | 2e-39 | 130.8 | Pfam-A | 1-232 (235) | alignment | ||
Range on Protein: 437-677
Range on HMM: 1-232/235.0
NPKLCRDPKVQAWDSTSYLV----DDTHFIHASTVTAPGKeyIGKAIICQAPfddkekgHPDTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDE
| | .| ... . |.| . ... .|.|..|. . | |..|.| ..| |.||||||. . ...|| .. .|.| .|| .|.|.|
nkkknRykdilpydktrvklkgsegpsdYInAnyvkgyke..kkkfIatQgP.......lkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpee
TGATENYGFAEVQLLEKHEMLNGHLLTRKIELTSGTWKHsdddpPIRTITHFQFLKWKEGEGLE-GEMSMDAFNYVNHRTRNNLDPIIVHSSLGTGRACA
.. ...|| .|.| || . . . .||.||.. .... |....... .|.. . | . .| . |....... |..||.| |.||..
eeesltygdikvelkekekedekeytlrklelkkkkees.....ekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgt
FVGAEYMFQMINTKKCGTARFFQVDFRTKRLGALQNGKQLFWVQNM
|| ............. . .|..| |. |. .|. .. ..
fvaldilleqleaeeevdvlqivkelRkqRpgmvqsleqYiflyka
|
|||||||||
| Y_phosphatase | Protein-tyrosine phosphatase | 437-677 | 2e-39 | 130.8 | In-house | 1-232 (235) | alignment | ||
Range on Protein: 437-677
Range on HMM: 1-232/235.0
NPKLCRDPKVQAWDSTSYLV----DDTHFIHASTVTAPGKeyIGKAIICQAPfddkekgHPDTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDE
| | .| ... . |.| . ... .|.|..|. . | |..|.| ..| |.||||||. . ...|| .. .|.| .|| .|.|.|
nkkknRykdilpydktrvklkgsegpsdYInAnyvkgyke..kkkfIatQgP.......lkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpee
TGATENYGFAEVQLLEKHEMLNGHLLTRKIELTSGTWKHsdddpPIRTITHFQFLKWKEGEGLE-GEMSMDAFNYVNHRTRNNLDPIIVHSSLGTGRACA
.. ...|| .|.| || . . . .||.||.. .... |....... .|.. . | . .| . |....... |..||.| |.||..
eeesltygdikvelkekekedekeytlrklelkkkkees.....ekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgt
FVGAEYMFQMINTKKCGTARFFQVDFRTKRLGALQNGKQLFWVQNM
|| ............. . .|..| |. |. .|. .. ..
fvaldilleqleaeeevdvlqivkelRkqRpgmvqsleqYiflyka
|
|||||||||
| 0037934 | (Phosphotyrosine protein) phosphatases II | 432-681 | 3e-34 | 114.1 | In-house | 5-241 (243) | alignment | ||
Range on Protein: 432-681
Range on HMM: 5-241/243.0
AMSAGNPKLCRDPKVQAWDSTSYLVDDTHFIHASTVTAPGkeyigKAIICQAPFDDkekGHPDTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPd
|.. | . .| . . ..| . .... .|.|. .. .. . |..|.| .. . |. .|||||.|. . |..||... .|.|..|| .|.|
allpenlsknrysdilpydhsrvklegsdyinanliyvtp.....rliatqgPlpe...tveddlasfwrmlwelgitvivmltelvElgrekcaqywp.
etGATeNYGFAEVQLLEKHEMlnGHLLTRKIELTsgtwkHSDDDPPIRTITHFQFLKWKEGEGLE-GEMSMDAFNYVNHR--------TRNNLDPIIVHS
| . .|| .|.||. ... .. |...|. . | |.. |...|...| | .. . | .| ...|. .... |..||
..gev.tygdftvtllseehl..ddytvrtllle.....nldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHC
SLGTGRACAFVGAEYMFQMIntkkCGTARFFQVDFRTKRLG-ALQNGKQLFWVQNMAFEL
| | ||. ... | .| ... . .. ..|..| | | |. |. ... .. ||
saGvgRtGtliaaylmllll....gvdleeavkllreqRpgkavqtpsqyrflyeallel
|
|||||||||
| subfamily_PTPRD_pd | Subfamily PTPRD | 493-683 | 2.3e-29 | 97.5 | In-house | 101-282 (564) | alignment | ||
Range on Protein: 493-683
Range on HMM: 101-282/564.0
PDTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDEtGaTENYGFAEVQLLEKHEMLNghLLTRKIELTSGTwkhsddDPPIRTITHFQFLKWKEG
..| | ||||||. . . .|| .. |.| .|| .|.|.. | ||.|| .|.| |..|. . |...|. . . |....|.| .| .
aetiedFWRmvweqnsstiVmltkleEkgkvkchkYWPek.g.tetygeltVtleeeeelad..yeirtfklkkkk......ssesreVrqFhFtsWPdh
EG-LEGEMSMDAFNYVNHRTRNNLDPIIVHSSLGTGRACAFVGAEYMFQMINTKKCGTARFFQVDFRTKRLGALQNGKQLFWVQNMAFELLI
... .| . |.. .... ||.|| | | || .|. ..| . |...| . . |..| |. .| ... .. | |
gvpesatslLdlirkvralnepdagPivVhCSaGVGRTGtfividamlerikeektvDiyqyvkalrkqRnamVqteeQYiFiheaileala
|
|||||||||
| subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 462-689 | 5.1e-28 | 92.7 | In-house | 78-290 (301) | alignment | ||
Range on Protein: 462-689
Range on HMM: 78-290/301.0
IHASTVTAPGKEYigKAIICQAPFDdkekghpDTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDETGATENYGFAEVQLLEKHEMLNGHLLTRK
||| . ..|. . |. |.|.. .|.| || |. .|| .| .|. ..|| |.| ... . . | .... .|. .|| .. |.
ihanwiptsGhph..rfiatqgPlk.......ntsedfwamlvqydvekivmlgqkvekleekceeylpvkisekldigrfkikiknkelilnkkiskrt
IELTSGTWKHsdddpPIRTITHFQFLKWKEGEGLEGemSMDAFNYVNHrTRNNLDPIIVHSSLGTGRACAFVGAEYMFQMINTKKCGTARFFQVDFRTKR
.|.. | | . ||.||.|. .| . . .. .. |. .. .. .||.|| | | ||. ||.|.||. . ..... ..| .|
levedstgkf.....atrtvthyqysewtdrgvPks..haelfdlmel.vkksekPivvhcsaGiGrsvafigteylareveadptieltealkhlrehr
LGALQNGKQLFWVQNMAFELLIKKLKM--H
..|. .||.|.. . |||. . .
wngvqtnsqlywmtlGtvyrlikeygfdmk
|
|||||||||
| subfamily_PTPRB_pd | Subfamily PTPRB | 459-685 | 2.8e-27 | 90.5 | In-house | 79-288 (293) | alignment | ||
Range on Protein: 459-685
Range on HMM: 79-288/293.0
THFIHASTVtaPGKEYIGKAIICQAPFddkekghPDTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDETGATeNYGFAEVQLLEKHEMlnGHLL
. .| |. . || . . | .| |. |.|.. ||||||..... .|| |..|.| .|| .|.|... .. .|| .|.|....|. .
sDYinanyi..pgynsprefiatqGPl.......petvddfWrmvwekkssiivmltqlvekgkvkCeeYWPadeepv.lyGdikvtlvaeeel..edwv
TRKIELTSgtwkhsddDPPIRTITHFQFLKWKEGEGLEGEMSMDAFN-YVNHRT--RNNLDPIIVHSSLGTGRACAFVGAEYMFQMINTKKCGTARFFQV
.|..... . .|......|. | . . | .. .| |.... .. ||.|| | | ||. .|. . ..| |... . . .
irelkiek........ekeerkvrqyhftsWpdhgvPektktlldfvrtvreaiektaskrPivvhCsaGvGRtGtfialdrllqaieeedyvdifgiva
DFRTKRLGALQNGKQLFWVQNMAFELLIKK
..|..| .|. || .... .|| ||
elReeRnllvqtekqYifihqcvldllrkk
|
|||||||||
| subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 492-679 | 1.8e-26 | 87.9 | In-house | 99-276 (288) | alignment | ||
Range on Protein: 492-679
Range on HMM: 99-276/288.0
HPDTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDEtGATENYGFAEVQLLEKHEMlnGHLLTRKIELTsgtwKHSDDdppiRTITHFQFLKWKE
.|| . ||..|...... .|| ...|.| .||..|.||. . .||| .|.|.|..|. .. ..||..| |. .. ..||..|.| | .
ladtvndfWelvyenktstivmltelveggktkCeeYWPda.dkpknyGsvtvtlveskel..edfvlrkllle....kkkte....leitqyqylaWpd
GEGLEGEMSMDAF-NYVNHRTRNNLDPIIVHSSLGTGRACAFVGAEYMFQMINTKKCGTARFFQVDFRTKRLGALQNGKQLFWVQNMAF
. | .. . .. . |. ... ||||| | | ||. |. .. . ....... . .| .| |. || .. ..
hgvPeskapllellrqvkvanqadtgpiivhCsaGvGrtgtFialdalidaveeedyiDvagtvaklRkqRallvqtlkqYefiyevll
|
|||||||||
| subfamily_PTPN3_pd | Subfamily PTPN3 | 442-672 | 9e-26 | 85.4 | In-house | 46-265 (280) | alignment | ||
Range on Protein: 442-672
Range on HMM: 46-265/280.0
RDPKVQAWDSTSYLVDDTH--FIHASTVT--APGKEYIGKAIICQAPFDdkekghpDTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDeTGATE
| . ..|.| ..... .| |..| |... . . |..| |.. .| . ||.|||. ... .|| ...|.| .|| .|.|. |. .
ryrdilpydatrvklkesetdyinanyvnmeipstglvnryiatqGPla.......ktatdfWqmvweqksslivmlttlverGrvkChqyWPe.tedel
NYGFAEVQLLEKheMLNGHLLTRKIELTSGTWKHSdddppiRTITHFQFLKWKEGEGLEGEM-SMDAFNYVNHRTRNNLDPIIVHSSLGTGRACAFVGAE
.|| .|.. .. . ..|.. |. . |.. |.|...|.| | . . . . .. . |.. . . .|..|| | | ||. .. |
eygefsvkceke..detksyvlrelvlkdketkee......rkilqlqylaWpdhgvPddsadflefvervrklrsgkeePvvvhCsaGigrtGvlille
YMFQMINTKKCGTARFFQVDFRTKRLGALQNGKQLF
...|.... | .| .|. .|
talalieaaepvypldivrtmrdqramlvqtasqyk
|
|||||||||
| subfamily_PTPN12_pd | Subfamily PTPN12 | 457-688 | 5.4e-25 | 82.9 | In-house | 66-283 (290) | alignment | ||
Range on Protein: 457-688
Range on HMM: 66-283/290.0
DDTHFIHASTVTAPGKEYigKAIICQAPFddkekghPDTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDETGATENYGFAEVQLLEKHEMLNGh
.. .| |. . . .. . | |.|. |.| . ||||.|... . ||| |...|.| .|| ||.|.|.. . ..| ||.| |.. . ..
egsdYinanfikgvegkl..eyiaaqgPL.......pktlddfWrmiweknveivvmaCrevelgkkkCerYWpeegeeelefgefevtleeekavddd.
LLTRKIELTSGtwkhsdddPPIRTITHFQFLKWKEGEGLEGEM-SMDAFNYVNHRTRNNLDPIIVHSSLGTGRACAFVGAEYMFQMINTKKC-GTARFFQ
.| | .... |... |.. .| . . ... .. . |... ... |..|| | | ||. . . .|. ......| . |.
flirtLkveaq........kesrkvyqfhYtaWPDhgvPssaksllelielvrelqesedaPlvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfd
V--DFRTKRLGALQNGKQLFWVQNMAFELLIKKLKM
. ..|..| . | .| | . ||. |.|..
lvlelrkqraalvqtkeqyelvykavaelvqkelei
|
|||||||||
| subfamily_PTPRG_pd | Subfamily PTPRG | 492-684 | 2e-24 | 80.8 | In-house | 100-289 (563) | alignment | ||
Range on Protein: 492-684
Range on HMM: 100-289/563.0
HPDTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDetGATENYGFAEVQLLEKHEMLNGHllTRKIELTSGTWKHSDDDPPIRTITHFQFLKWKE
.|| . ||||.|. ... .|| .. |.| .|| .|.| .|.|| .|.| |.. . .|.. . |. .. ........ || .
lkdtfddFWrmiWeqnvaiivmitnlvergrrkcdvYWPk..desetygalqvtlieeevlalyt..vrtlviknlklkkkkqcdteklvrqyhytkWPd
GEglEGEMSMDAFNYVNHRTRNNLD---PIIVHSSLGTGRACAFVGAEYMFQMINTKKCGTARFFQVDFRTKRLGALQNGKQLFWVQNMAFELLIK
| |. ..|... . | . ||.|| | |.||. .. . . . |.... | .|..| .|. | .. . |..
hg..vPehslpvLifvkkssaankaeaGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvqteEqYiflhdalleaias
|
|||||||||
| subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 473-680 | 2.3e-24 | 80.8 | In-house | 72-264 (283) | alignment | ||
Range on Protein: 473-680
Range on HMM: 72-264/283.0
EYIGKAIICQAPFDDkekghpdTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDEtgATENYGFAEVQLleKHEMLNGHLLTRKIELTSGtwkHS
. | ||.|.|.|. |. ||.||.| ..| .|| ...|. .|| .|.| . .|.|| | | ..|. . . ... | |
kqdkkyiiaqsPldr.......tvvdfWkmvfdekitaivmltklqedlrikCsqyWPkr..GsedyGeftvtl..rkettsnsfiikelllrvn...ss
DDDPPIrtITHFQFLKWKEGEGLEGEMSMDAFNYVNH-RTRNNLDPIIVHSSLGTGRACAFVGAEYMFQMINTKKCGTARFFQVDFRTKRLGALQNGKQL
. . ..|.|. | | . |. || | .|... ||.|| | | ||. .|..| . . |. | .| .|.|. |
akstll..lahyqvidWleygeqaiinslvkfnkvislqteskkgPivvhCstgiGrtavfiaasasvkdaltesvvdvfavvkimreqrmmavqtldqy
FWVQNMAFE
| ....|
klvhelvle
|
|||||||||
| subfamily_Ptp69D_pd | Subfamily Ptp69D | 457-673 | 5.9e-24 | 79.7 | In-house | 74-277 (307) | alignment | ||
Range on Protein: 457-673
Range on HMM: 74-277/307.0
DDTHFIHASTVTAPgkEYIGKAIICQAPFDDkekghpdTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDEtgATENYGfaEVQLLEKHEMLNGH
.|. .| || . . . | |. |.| . | . ||||... | .|| .. | .|| .|.|.| . .|| .. .| ..
edsdYinasfikgy..kekkkfiaaqdPvea.......tigDfWRmiaeqevtlivmlsnlteknrkkcakYWpie..devqyg..dilvklvseekhsd
LLTRKIELTSGTwKHSDDDPPIRTITHFQFLKWKEGEGLEGEMSM-DAFNYVNHRTRNNLDPIIVHSSLGTGRACAFVGAEYMFQMINTKKCGTARFFQV
|..... ..| . . | .. .... ||. . | .. . . |.. ..| ||.|| |.|.||. || . ..| ... .. .
yiiReldvskkk.eesgevedsrkvvqyhytgWkDskvPevargllklieqvrelyklnrsPivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvk
DFRTKRLGALQNGKQLFW
| | .| .|. .| .
dLrsqRnllvqsleqYvf
|
|||||||||
| subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 458-711 | 2.3e-23 | 77.8 | In-house | 75-308 (319) | alignment | ||
Range on Protein: 458-711
Range on HMM: 75-308/319.0
DTHFIHASTVTAPGKEyiGKAIICQAPFDdkekghpDTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDETgaTENYGFAEVQLLEKHEMlNgHL
.. .| || . . .. | | ||| . .| | ||||||. .. ||| ... |.. |. .|.|.|. |.|| |.|.|..|. . ..
gsdyinasfidgyqer..ekfiatqaPle.......ntiedfWrmvWeeessivvmltklveklkvklkkywpeen..feeyGrlivtleeeeel.e.dy
LTRKIELtsgTWKHSDDDPpiRTITHFQFLKWKEGEGLEGEM-SMDAFNYVNHRTRN-NLDPIIVHSSLGTGRACAFVGAEYMFQMINTKKCGTARFFQV
||..| | |. . |...|||...| . . | . .| .. ... ... . ||.|| | | || .|. . |.. .. .
iirklkl...nkkssevet..RevkhfqyteWpdhdvPekatslldllkrirksrektqsgPivvhCsaGvGRtGtfivldamlervkeegvlDvfstvs
DFRTKRLGALQNGKQLfwvqNMAFELLIKKLKMHHLKFEMEEQWNFLKNYSNKETD
||.| |. .| .. .| |.. ... . ..|... . ||. ..|..|
rlRtqRnimvqrpeqY....kfiyealleaveagdteievqdlrdrlkqlaekvad
|
|||||||||
| subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 432-683 | 2.6e-23 | 77.4 | In-house | 31-271 (285) | alignment | ||
Range on Protein: 432-683
Range on HMM: 31-271/285.0
AMSAgNPKLCRDPKVQAWDSTSYLV--DDTHFIHASTVTAPGKEYiGKAIICQAPFddkekghPDTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYF
| | || | | |.. . | .. | .|||| . |||. | | |. |.| ||.|... . .||.| | ..| ||.|| |.
ayea.npdlnryadvrcieetrvvlknhdrdyihaswmrmpgkdq.styittqgpl.......petlsdfwhmiyqekiayvlmlctlfeggvekcalyy
PDETGATENYGFAEVQLLE-KHEMLNGHLLTrkiELTSGTWKHSDDDPpiRTITHFQFLKWKEGEGLEGEMSMD-AFNYVNhRTRNNLDPIIVHSSLGTG
|.. | ..| |. | | | | . | .| || . . .| . | | | . | | ...|. . . || || | | |
peklgevvkfgkyeitlteckeeaiagtiln...altvintedassep..lymnhvqvpwwpdqlapedarpmielykwvk.kvnpkekpicvhcsagvg
RACAFVGAEYMFQMINTKKCGTARFFQVDFRTKRLGALQNGKQLFWVQNMAFELLI
|...||| .| | . ..|. |. |.|. |.... . .| .|
rtatfvgidyatirimenpniemldivremramrfqavqshmqflflyvvlmeyfi
|
|||||||||
| subfamily_PTPN13_pd | Subfamily PTPN13 | 449-682 | 3.8e-23 | 77.1 | In-house | 49-269 (273) | alignment | ||
Range on Protein: 449-682
Range on HMM: 49-269/273.0
WDSTSY-LVDDTHFIHASTVTAPGKEYIGKAIICQAPFddkekghPDTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDETGATEN-YGFAEVQL
.| | | |.. .| || . .| . ..|.|| |. |.| . ||.|||. .|. ..| . |.| || ||.|.... . .. ||.|
ydetrvklgdeggyinaslikvpvgkdeyeyiacqGPl.......PetvkdfwqmvweqkaeviamvtlekekgkvkchrywPesknkklkvsnrlevel
LEKHEMlNGhLLTRKIELTSGTWKHsdddppIRTITHFQFLKWKEGEGLEGEMSMDAFNYVNHRTRNNLDPIIVHSSLGTGRACAFVGAEYMFQMINTKK
|. .. .| . |..... .. | ..|..| || . . ... | | ... ||.|| | | ||. ... . ....|. .|
lkvqkl.dg.fvvralavkdsesge......srevahlnfvkwPdhgvPssaaellqfvaevrrlqtdagPivvhcsaGiGrsGtlitidvvlglierdk
CGTARFFQVDFRTKRLGALQNGKQLFWVQNMAFELL
. ..| .| | .| .| .| . . |.|
efdvkeivrklreqrqgvvqtkdqyifvykailevl
|
|||||||||
| subfamily_PTPN6_pd | Subfamily PTPN6 | 492-650 | 3.9e-23 | 76.9 | In-house | 107-262 (306) | alignment | ||
Range on Protein: 492-650
Range on HMM: 107-262/306.0
HPDTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDETGATEnYGFAEVQLLEKHEMLNGHLltRKIELTSGtwkhsDDDPPIRTITHFQFLKWKE
..| . ||||||. .. .|| . .| | .|| ||.|||. .| || .|. ...... . | |.. .. ... |.. ...| .| .
lettvsdFWrmvwqensrvivmttkevErgkekCarYWPdeeekee.yGkisvtnvseksladYil..Relsvskk.....kkkkeerevfqyhfksWPd
GEG-LEGEMSMDAFNYVNHRTRNNL----DPIIVHSSLGTGRACAFVGAEYMFQMINTKKCGTA
. .. .| .. ||..... ||.|| | | || .|. . . ..|..|.. .
hgvpkdpgavLdfledvnrkqeeleeaeagpivvhCsaGiGRtGtfiviDillkliekkgldad
|
|||||||||
| subfamily_PTPRK_pd | Subfamily PTPRK | 492-680 | 4.1e-23 | 76.7 | In-house | 95-275 (314) | alignment | ||
Range on Protein: 492-680
Range on HMM: 95-275/314.0
HPDTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDETgatENYGFAEVQLLEKHemLNGHLLTRKIELTSgtwkHSDDDPPIRTITHFQFLKWKE
..| . |||.|.| ... .|| ...|.| || .|.|..| | || .|.|.| . |. |..| .. . ||.. .||||.| .
lqetvkdfWrlvydencasivmltelvevgrvkClkyWPedt...evygdikvelvete..llaelvvrifrvek....largqeeirevrqfqflgWpd
GEGLEGEMSMD-AFNYVNHRTRNNLDPIIVHSSLGTGRACAFVGAEYMFQMINTKKCGTARFFQVDFRTKRLGALQNGKQLFWVQNMAFE
. . .. |.. . .. .|.|| | |.||. .|. . . .||.... . ..|... .. .| .. ....|
hdvPvsatgllklvrrvkksqeeeaGrivvhCsaGaGrtGtfiaidivldmieregvvdvfnavktlrsrkvnmveteeqykfiydvile
|
|||||||||
| subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 456-681 | 4.3e-23 | 76.9 | In-house | 71-282 (305) | alignment | ||
Range on Protein: 456-681
Range on HMM: 71-282/305.0
VDDTHFIHASTVTapGKEYIGKAIICQAPFDdkekghpDTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDETGATENYGFAEVQLLEKHEMlNG
.||...| || | | . | |. |.|.. .| . |||...... . .|| ....|.| .|| .|.|.... ....| .|.| ..... ..
lddsdyinasyvd..gykrkkkyivaqgPlk.......ntvadfWrliveekvstivmltklveggkdkCrqYWpesktekkefgefsvelksekta.sd
hLLTRKIELTSGTWkhsddDPPIRTITHFQFLKWKE-GEGLEGEMSMDAFNYVNHRTRNNLD-PIIVHSSLGTGRACAFVGAEYMFQmiNTKKCGTARFF
...||.... | ||....|. .| . | . .. .. |... ... . |..|| | | ||. .|. . ... || .. .|
.yieRklkisiede.....dkesrtvlqyqltdWPdhGvpqfatsllslikrvqkdqkkdkgvpllVhCsagvgRtGvfiavdiale..rlkkEevvdvf
QV--DFRTKRLGALQNGKQLFWVQNMAFEL
.| |.||....|. .| . .. ||
evlkqlRskrmkmvqtldqYvflhdaldel
|
|||||||||
| subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 493-678 | 1.2e-22 | 75.2 | In-house | 74-260 (270) | alignment | ||
Range on Protein: 493-678
Range on HMM: 74-260/270.0
PDTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDETGATENYGFAEVQLLEKHEMLNGHLLTRKIELTsgTWKHsdddppIRTITHFQFLKWK-E
| | .|||||.|....| .|| ...|.| .|| ||.| |.. . .. . ... | .| . ......|. .. . .| ..||.. .| .
pttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkekvkledgkikvlalseekeegyiltrlrle..ekge......errlvHfwyntWpdh
GEGLEGEMSMDAFNYVN-----HRTRNNL---DPIIVHSSLGTGRACAFVGAEYMFQMINTK-KCGTARFFQvDFRTKRLGALQNGKQLFWVQNMA
| | . |... . .. .|....| .|..|| | | ||. .. .......... |. ... . . | .| .| .| ....
gvpreedsslstdqllkmlravrrsekeldkaePllvHcsaGvgRtGtlialDiavrlLeetkkvdvlaiie.elRkdRmalvqhpeqyeflykav
|
|||||||||
| subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 493-679 | 1.2e-22 | 75.1 | In-house | 101-280 (290) | alignment | ||
Range on Protein: 493-679
Range on HMM: 101-280/290.0
PDTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDEtgATENYGFAEVQLLEKhEMLNgHLLTRKIELTSgtwKHSDddPPIRTITHFQFLKWKEG
..| ||...|. . | .|| ..|.|.| .|| |.||. |..|| ...||. |.|| . .||.|... |.|. . ...|..|. |..
sntlvdFWkliwqekvtiivmltniieegkvkCqqYWpds..dtkaygefsikllne.etln.eyierklevkn...knsa..gakqsvtqyqitnwdst
E-GLEGEMSMDAFNYVNHRT-RNNLDPIIVHSSLGTGRACAFVGAEYMFQmiNTKKCGTARFFQV--DFRTKRLGALQNGKQLFWVQNMAF
. . . .. ... ... .. .|.|| | . ||. |. |. . .|. | ||| |... | .| .|. . .. .
gkvtnpqtillvieemyktqrkrgntsivvHCSdtvgrsavfcaaattin..kcktegvidvfqvlksqRiqkpgsvqtvqqyqgifqivl
|
|||||||||
| subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 479-683 | 1.4e-22 | 75.1 | In-house | 92-281 (318) | alignment | ||
Range on Protein: 479-683
Range on HMM: 92-281/318.0
IICQAPFddkekghPDTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDETgaTENYGFAEVQLLEKHEMlnGHLLTRKIELTSgtwKHSDDDppi
| .||| |.| | ||||||. .. .|| |..|.| .|. ||.|.. ...|| |.| |. |. .... |....| .....
iaaqaPl.......petieDfWrmvWeqnsavivmltqeeergkakvhryWPskg..srsygklvvelkeevel..sdyvlrefkvtr...teeees...
RTITHFQFLKWKEGEGLEGEMSM-DAFNYVNHRT-RNNLDPIIVHSSLGTGRACAFVGAEYMFQMINTKKCGTARFFQVDFRTKRLGALQNGKQLFWVQN
|.. ... .| . .| .|. | |.. ... .||.|| | | ||. |. . . . |. . . .|..| | .| .. .
rqvrqyhytsWpdegvpesgaslldlvrqvskaqqksgagpivvhCsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqtedqyefiyd
MAFELLI
. | |.
vlleala
|
|||||||||
| subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 446-685 | 1.7e-22 | 74.9 | In-house | 50-279 (281) | alignment | ||
Range on Protein: 446-685
Range on HMM: 50-279/281.0
VQAWDSTSYLV------DDTHFIHASTVTApgKEYIGKAIICQAPFddkekghPDTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDETGaTENY
. |.| | | .| .| |. | . . . |..|.| |.. ..||.|||..... .|| . .|.| || ||.||.. . .|
ivaYDatrvkvtpneenkntDYinanfvpg..ykgekeyiatqgPv.......PaslvafWqmvweqkvsaivmvtreieagklkChrYWPddns.elky
GFAEVQllEKHEMLNGHLLTRKIELTSgtwkhsdDDPPIRTITHFQFLKWKEGEGLEGEMSMDAF-NYVNHRT-RNNLDPIIVHSSLGTGRACAFVGAEY
| |. ..| . . ..||..|. .. . |.........| . . . . | . |.. | ... |...| | | ||. .... .
gdvtvk..staeeekatyierkfkler.......esgetreveqlaytaWPdhGvPattkellefrkevlkltekktkaplvihCsaGvGrtGtyialDr
MFQMINTK-KCGTARFFQVDFRTKRLGALQNGKQLFWVQNMAFELLIKK
... .... . . ..| .| .| | .| . . | |.
lvkaveaeleeldvkavvaelrkernlmvqtvvqyefvykavldaldke
|
|||||||||
| subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 495-690 | 7.6e-22 | 72.6 | In-house | 40-229 (255) | alignment | ||
Range on Protein: 495-690
Range on HMM: 40-229/255.0
TRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDETGatENYGFAEVQLLEKHEMLNGHLLTRKIELTSGTWKHSdddppiRTITHFQFLKWKEGEG
| . |.... |... ||| | |.||.|| .||| | | .|.|.. . . . | |..| .| | |. .|..|... | | .
tvdkfyqtivqtktevvvmlcdfaeegvekcssyfplekd..eklkladvnvtttkssadvvlrtleitstlgekkkt......htvkhysykGWiekna
LEgeMSMDaFNYVNHRTRNNlDPIIVHSSLGTGRACAFVGAEYMFQ----MINTKKCGTARFFQV--DFRTKRLGALQNGKQLFWVQNMAFELLIKKLKM
| .. . .. . |. ...|| | | ||. ||| ||...| ..| . . . .. . | || .|... || . | ..|. | ..
Pe..lare.ilnilkvvrds.ksvvvhCstGiGrsaafvlaelvyqkmirsldttetveldylslleelrskrkraihtPlqlafsilmvldlvfpkgel
HH
.
ea
|
|||||||||
| subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 458-682 | 9.2e-22 | 72.6 | In-house | 83-290 (298) | alignment | ||
Range on Protein: 458-682
Range on HMM: 83-290/298.0
DTHFIHASTVTAPGKEYigKAIICQAPFddkekghPDTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDEtgATENYGFAEVQLLEKHEmlNGHL
.. .| || . | .. |..|||. . | | |||||.. .. .|| .. | . |. .|.||| .|.|| .|.||.|.| . |
esdYiNAsflhaykgrn..afiatqaPl.......tetvedFWrmvteedigtiVmltnleeldktkyhkywPde..gketygeitvsllskee..fadl
LTRKIELTSGTWKHSdddppiRTITHFQFLKWKEGEGLEGEMSMDA-FNYVNHRTRNNL-DPIIVHSSLGTGRACAFVGAEYMFQMINTKKCGTARFFQV
.||..... . ... |.. ...| .| . | . |. . . |. .... |.||. | |.||. .|. . ... ..... .
ivrklkvskkkeeke......revrqlhftsWpdkgvpenatsvldllrkvrasqqqagnkpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvk
DFRTKRLGALQNGKQLFWVQNMAFELL
.|.|| ||.| .| .. .. | |
vlRkkrpgavqteeqYvfiyeavleal
|
|||||||||
| subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 461-690 | 9.9e-22 | 72.3 | In-house | 69-285 (307) | alignment | ||
Range on Protein: 461-690
Range on HMM: 69-285/307.0
FIHASTVTAPGKEyiGKAIICQAPFDdkekghpDTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDETGATENYGFAEVQLlEKHEmLNGHLLTR
.||| . | | | .| | . .|. ||| |. . . |.| |...| . || .|.| | | . .| | . . | . |.
yihanylgiaikp..kkficaqgple.......ntqysfwamaiqekvesvimlckvielakikceqywpleegqklvfgeapnti.svan.lgakklap
KIELTSGTWKHSDDDPPIRTITHFQFLKWKEgEGLeGEMSMDAFNYVNhRTRNNLDPIIVHSSLGTGRACAFVGAEYM-FQMINTKKCGTARFFQVDFRT
.| | . | |||.|.|. .| . .| .. . | | .. .| . .|..|| | | ||. . |. .. .||. . | . . ..|.
dedlinvttlkvdwaqksrtiqhlqwenwpd.rgv.pqinltainlle.avrydtnpvvvhcsaGvGrsGtivaislvqdkmiaGinckdmkklveelrs
KRLGALQNGKQLFWVQNMAFELLIKKLKMHH
.| |.|. | ... . .| .... | .
qrhyaiqteaqylylhrvlleyflelykety
|
|||||||||
| subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 455-687 | 1.7e-21 | 71.6 | In-house | 62-277 (288) | alignment | ||
Range on Protein: 455-687
Range on HMM: 62-277/288.0
LVDDTHFIHASTVTApGKEYIGKAIICQAPFddKekGhpdTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDETGATENYGFAEVQLLEKHemln
| ||..| |. | . ..| . | .|||. . | | | .|.|. .. |.|| |...| | .| ||| . | . .| . .|.
lsddpdfyiaanvvs.sakykrrlicaqaPl..n..g...tieelWkmllesdveyivmlcellekGkeksaeyfPsklGekarigrlctvvkkkr....
gHLLTRKIELTSGTWKHSDDDPPirTITHFQFLKWKEgEGLEgEMSMDAFNYVNHRtRNNLDPIIVHSSLGTGRACAFVGAEYMFQMINTKKCGTARFFQ
. . .... .. ... . . .|.|.. .|. | . .. .. .. ||.|||| |.||. ... . ... . . | .
.adidklvkvsllriskegeekv..ivkilhlleWdd.dgvP.enylsplrllevl.kslqkPivvhssaGvGrtgtlililialeslrlddflgirsll
VDFRTKRLGALQNGKQLFWVQNMAF-ELLIKKLK
| .| |.| .| .| . . |||.|| |
aklreerfkaiqtemqylyvhrcvleelllkkyk
|
|||||||||
| subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 494-678 | 8.5e-21 | 69.2 | In-house | 97-274 (287) | alignment | ||
Range on Protein: 494-678
Range on HMM: 97-274/287.0
DTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDETGatENYGFAEVQLLEKHemLNGHLLTRKIELTSgtwkhSDDDPPIRTITHFQFLKWKEGE
.| ||....| . | .|| || .|| ..| .|.|.|. .| ...||... | . . ||.|.. .. . . .... .|. .|..
ntarnfWkliddrnvtaivmlcqekendeevcyqyWpeeks..vvlGeyniellnee..vnagyierklevkn.....knkagdkqqvkqyqitnWdstg
-GLEGEMSMDAFNY--VNHRTRNNlDPIIVHSSLGTGRACAFVGAEYMFQmiNTKKCGTARFFQV--DFRTKRLGALQNGKQLFWVQNMA
| . .. .. ..| | | .|.|| | . ||. |. |. . ..|. |. ||| | .. |..| .| ....
kvtepqtillvieemyktqrkrgn.tsivvhCsdtvGrsamfcaaattin..kckteGviDvfqvlksqriqkpgsvqtveqykfindiv
|
|||||||||
| subfamily_PTPRA_pd | Subfamily PTPRA | 494-679 | 1.4e-20 | 68.4 | In-house | 112-292 (330) | alignment | ||
Range on Protein: 494-679
Range on HMM: 112-292/330.0
DTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDETGATenYGFAEVQLleKHEMLNGHLLTRKIELTsgTWKHSDDDPPIRTITHFQFLKWKE-G
.| | ||||.|. ... .|| .. | .|| .|.||| | || |.. ..|.. .. ||. .. .. .. . | .. | | | . |
etvedfwrmiweqksativmltelkerkeekcaqywPdeGlvt..yGnirvev..edetvlvdytvrkflvq..qlpdatrekksrlvrqfhftswPdvG
EGLEGEMSMDAFNYVNHRTRNNLDPIIVHSSLGTGRACAFVGAEYMFQMINTKKCGTARFFQVDFRTKRLGALQNGKQLFWVQNMAF
|. .. .. |.. ... .||.|| | |.||. .|. . ......... | .|..| .| .| .. ..
vPfepiGmlkllkkvkklnqqsagpivvhcsaGvGrtGtfivldavlervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvll
|
|||||||||
| subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 457-697 | 1.9e-20 | 68.2 | In-house | 46-273 (290) | alignment | ||
Range on Protein: 457-697
Range on HMM: 46-273/290.0
DDthFIHASTVTAPGKEyigKAIICQAPFDDKEKGHPDTRESFWRMVWDTRATYVVMCCQIMENGVQ----KCGRYFPDETGATENYGFAEVQLleKHEM
|| .|||. || | . |. |.| . . . | |.|| |. . ... ||| |. .|. . | .|.|.. | ... .|. |. .
dd..yiHAnrvtcpngl...rliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCakYvpesvgeelkfkgltvkC..kske
LNGHLLTRKIELTSgtwkhsdDDPPIRTITHFQFLKWKEGEGLEGEMSM-DAFNYVNhrtrNNLDPIIVHSSLGTGRACAFVGAEYMFQMIN-TKKCGTA
. . ||..... || |.|| .. |.. . | . .. .. ..|. .. |.||| | | |. . .|.| |.. .
keddvetRelvvkf.......ddeeeftvtHsllkgWnklnvqedtktllsliqkvk....asktpvivHcvdGiSrsAalaaiilgyQkiaetsgsvkl
RFFQVDFRTKRLGALQNGKQLFWVQNMAFeLLIKKLKMHHLKFEMEE
. . | .| |... ..| .| .. ||... ... . | |.
edvlkalrkqralaitsalelafvdagiv.llaievldqfaeeetek
|
|||||||||
| subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 493-682 | 2e-20 | 68.1 | In-house | 62-242 (250) | alignment | ||
Range on Protein: 493-682
Range on HMM: 62-242/250.0
PDTRESFWRMVWDTRATYVVMCCQIMENGVQkCGRYFPDEtgATENYGFAEVQLLEKHEMlnGHLLTRKIELTSGTWKHSdddppiRTITHFQFLKWKEG
..| | |||||.. .. .|| .. |.. . . .|.| | .|.|| |.||.|.|. . . .||. |.. . ... |.. ...|. | .
qatiedfWrmvleeksgtivmLtnLkesekt.yhqywPve..kaekyGdvtvsllskeef..adytkrklklskakkade......rivrqlhfvvWPdk
EGLEGEMSM-DAFNYVNHRTRN-NLDPIIVHSSLGTGRACAFVGAEYMFQMINTKKCGTARFFQVDFRTKRLGALQNGKQLFWVQNMAFELL
| .. . . |. .. . |.||. | |.||. ||. . ... ....| . . .|..| .|.. .| .| ... . |
gvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidavlerlkkekvvdvfkvikvlrkdrphavesleqyvfvyeiilkal
|
|||||||||
| subfamily_hpo-7_pd | Subfamily hpo-7 | 496-687 | 3.3e-20 | 67.1 | In-house | 47-232 (263) | alignment | ||
Range on Protein: 496-687
Range on HMM: 47-232/263.0
RESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDETGatENYGFAEVQLLEKHEMLngHLLTRKIELTSGTW-KHSdddppIRTITHFQFLKWKEGEG
..|.... |... ||| | |.||.|| .||| | | .|.|.. . . .| . .||.| | ..|..|... | | ..
idkfyqtivqtktevvvmLcDfneegvekcssyfPlekd..ekqklanvnvcttkvqs..dvllktlellstlgeKkk.....thtvkhysykgWieknd
LEGemSMDAFNYVNHrTRNNlDPIIVHSSLGTGRACAFVGAEYMFQ----MINTKKCGTARFFQV--DFRTKRLGALQNGKQLFWVQNMAFELLIKKLK
| . . .| .. .|| ...|| | | ||. ||. || ..| ..| . . . .. . | .| .|... || . | ......
pel..areilnilkv.arns.kslvvhcstGiGrsaafsvaElvyqkmirsldttstveldylsLleelrssrkraihtPmqLafsilmvLdfvlnnfa
|
|||||||||
| subfamily_PTPRN_pd | Subfamily PTPRN | 493-640 | 6e-20 | 66.1 | In-house | 110-249 (297) | alignment | ||
Range on Protein: 493-640
Range on HMM: 110-249/297.0
PDTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDETgaTENYGFAEVQLLEKHEMLNGhLLTRKIELTSgtWKHSDddppIRTITHFQFLKWKEG
..| .||.|||. .. .|. ... |.||..| ||.||| .| |.. ||.|. .| . | | . | . |. ||.| | || |.|
astvadfwqmvweqGvvvivnltrleeegvkqckrywpdeG..sevyhiyevhlvsehiwcdd.ylvrsfylkn..lqtse....trtvtqfhflswpee
EGLEGEMSMDAF-NYVNHRTRNNLDPIIVHSSLGTGRACAFVGAEYMFQ
. |. | || | ||.||.| |.||. ... . . .
gvPasaksllefrrkvnksyrGrscpivvhcsdGaGrtGvyilidlvln
|
|||||||||
| subfamily_PTPN9_pd | Subfamily PTPN9 | 493-670 | 6.4e-20 | 66.4 | In-house | 95-278 (297) | alignment | ||
Range on Protein: 493-670
Range on HMM: 95-278/297.0
PDTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDETGATENYGFAEVQLLEKHEMlnGHLLTRKIELTsgtwkHSDDDpPIRTITHFQFLKWKE-
. | . ||||||. .. .|| ...|.| |||.|.|.|.......|. .|. .| .|. . .|..|.. ..... .|..|||||| | .
kktvsdfWrmvWeqevlvivmttrvvergrlkcgqyWpleeessaefgdlsvsnveveee..edykvrvleik.....nvkte.esrkvthfqflsWPdy
GEGLEGEMSMDAFN-----------YVNHRTR--NNLDPIIVHSSLGTGRACAFVGAEYMFQMINTKKCGTARFFQVDFRTKRLGALQNGKQ
| ... .| . .. .... . ||.|| | | ||. .|. .. . .... . .||.| ..| .|
GvPssaaslldvlekvrekqalavkelgdewkghpsgPPivvhcsaGiGrtGtfitldiclsrleevgtvdvvetvkllrtqrafsiqtpeq
|
|||||||||
| 0036282 | (Phosphotyrosine protein) phosphatases II | 477-676 | 1.2e-19 | 66.1 | In-house | 18-164 (174) | alignment | ||
Range on Protein: 477-676
Range on HMM: 18-164/174.0
KAIICQAPFDdkekghpdtresFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDetgatenygfaevqllekhemlnghlltrkieltsgtwkhsDDDP
. |..|.|.. ||.|... . |.|||... .|.| || .|.|. . .
rliagqgpla............fwemlkelgittvvmlleekelglykcinywpe.........................................lred
PIRTITHFQFLKWKEGEGLEGEMSMDAFNYVNHRTRN-NLDPIIVHSSLGTGRACAFVGAEYMFQMINtKKCGTARFFQVDFRTKRLGALQNGKQLFWVQ
. |.. ....| | .. . .. .....|.. . . |..|| | | ||. ..|.| .| ... . | . |..| |. |. |. ...
lerlgiqylylpwpDhgvpdlsillefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtpsQyrfly
N
y
|
|||||||||
| subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 493-676 | 1.2e-19 | 65.5 | In-house | 83-262 (274) | alignment | ||
Range on Protein: 493-676
Range on HMM: 83-262/274.0
PDTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDETGA--TENYGFAEVQLLEKHEMlNGHlLTRKIELTSGTWKHSdddppirtITHFQFLKWK
| | . ||||.. .... .|| .. |. ||| .||||.... .|.|| |.. .. | |.. ||. | . . ..| ..|. . .|
pntvadfWrmiyqeevqvivmltklkeaneqkCavyfPdaedyeiserygdveikvekiver.ndy.svrklvlkylerers........vkhywytdWP
EGEGLEGEM-SMDAFNYVNH-RTR--NNLDPIIVHSSLGTGRACAFVGAEYMFQMINTKKCGTARFFQVDFRTKRLGALQNGKQLFWVQN
. . . .| . |.. |.. ..| |..|| | | ||. .|.... . .. .. ...| .| | .|. .| .. .
dhksPddantlldlvleveesreeenaklapvvvhCsaGiGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihr
|
|||||||||
| 0046846 | (Phosphotyrosine protein) phosphatases II | 488-682 | 1.4e-19 | 66.0 | In-house | 28-173 (176) | alignment | ||
Range on Protein: 488-682
Range on HMM: 28-173/176.0
KEKGHPDTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDetgaTENYGFaevqllekhemlnghlltrkieltsgtwkhsdddppirtitHFQFL
. ..|.| ..|..|... . |.||.... .| | || .|.|. |..|. ....|
tqgplprtladflemlkelgitavvnlteevelgrlkcpnywpe....leklgi.........................................qylhl
KWKEGEGLEGEMSMDAFNYVNHRTRNNlDPIIVHSSLGTGRACAFVGAEYMFQmintKKCGTARFFQVDFRTKRL-GALQNGKQLFWVQNMAFELL
| .. . | ........ . ... |..|| | | ||....| | . .|. .. .| .| ||.|. .|. ... .. .||
pwpDhgvpdlelllellefirealkeg.gpvlVHCsaGigRtgtlvaayllel....ekglsveealalvreqRplgavqtpeQyrflyefellll
|
|||||||||
| subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 492-709 | 1.8e-19 | 65.3 | In-house | 77-278 (284) | alignment | ||
Range on Protein: 492-709
Range on HMM: 77-278/284.0
HPDTRESFWRMVWDTRATYVVMCCqimengVQKCGRYFPDETGATENYGFAEVQLLEKHEMlnghLLTRKIELTSGTwkHSDDdppIRTITHFQFLKWKE
..| . ||||.|. ... .|. .|| .|.| .. .|. . .|...|. | |.|||. . . | ||.|. | || | .
ldntladfWrmiweyncstivllt......kdkcsqywplkivikeerfkvkvdsveesee....yvvrdielsedg..kekd...irkirqfhflgwpd
-GEGLEGEMSMDAFNYVNHRT--RNNLDPIIVHSSLGTGRACAFVGAEYMFQMINTKKCGTARFFQVDFRTKRLGALQNGKQLFWVQNMafelLIKKLKM
| . | . |.| | |. .|.|| | |.||. ... . ...... .| | |.| .| .|. | ... |... .
vgvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrtgvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysa....lleehlf
HHLKFEMEEQWNFLKNYSNKE
| . . .|.. |||
ghsdvalpdfpayleelsnks
|
|||||||||
| subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 492-709 | 2e-19 | 65.1 | In-house | 113-314 (319) | alignment | ||
Range on Protein: 492-709
Range on HMM: 113-314/319.0
HPDTRESFWRMVWDTRATYVVMCCqimengVQKCGRYFPDETGATENYGFAEVQLLEKHEMlnghLLTRKIELTSGTwKHSDddppIRTITHFQFLKWKE
..| . ||||.|. ... .|. .|| .|.| .. .|. . .|...|. . |.|||. . |. | || || | || | .
ldntladfWrmiweyncstivllt......kdkcsqywplkivikeerfkvkvdsveetae....yvvrdielsedg.kekd....irkitqfhflGwpd
-GEGLEGEMSMDAFNYVNHRT--RNNLDPIIVHSSLGTGRACAFVGAEYMFQMINTKKCGTARFFQVDFRTKRLGALQNGKQLFWVQNMafelLIKKLKM
| . | . |.| | |. .|.|| | |.||. ... . ...... .| | |.| .| .|. | ... |... .
vGvpdypsdlmrlvkkvrhltskenhranivvhcsaGvGrtGvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysa....lleehlf
HHLKFEMEEQWNFLKNYSNKE
| | . .|.. |||
ghsdvampdfpayleelsnks
|
|||||||||
| subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 493-683 | 3.3e-19 | 63.4 | In-house | 96-277 (515) | alignment | ||
Range on Protein: 493-683
Range on HMM: 96-277/515.0
PDTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDETGATENYGFAEVQLLEKHEMlnGHLLTRKIELTSGtwkhsdDDppIRTITHFQFLKWK-E
. . . |||.|.. . | ..| . |. |||.|.|| | . ..| .|.|. . . . ||.... | || .||.| |.| .| .
kasvddfWrlvlqenvttiamvtklkegdkikcgkyWPdkpgdsvkfGsikvelvsleac..tggikrkltvlkg......dd..srtvtqfhfteWPdk
GEGLEGEMSMDAFNYVNHRTRNNLDPIIVHSSLGTGRACAFVGAEYMFQMINTKKCGTARFFQVDFRTKRLGALQNGKQLFWVQNMAFELLI
| . . | . . |.|.| | | ||. .. .. . ..| . | | || .| | .. .. | |
GvpkhtssllklikevkadhgqythpliihcsaGvGrtGvvisidsvvahakttrmvdvfnfvtnirqkrpylvqtqeqyafiygavledll
|
|||||||||
| subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 493-672 | 1.2e-18 | 61.7 | In-house | 104-273 (290) | alignment | ||
Range on Protein: 493-672
Range on HMM: 104-273/290.0
PDTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDETGATENYGFAEVQLLEKHEMlNGHLLTRKIELTSgtwKhsdDDPPIRTITHFQFLKWKEG
|| .|||| .......|| |...|.| || .|.|.. | . .| | |... . .. . . . | |. . |.. | .
kdtvidiwrmvlqekvaaivmlceliedGkakceqyypekeGevltfGeitvlcseeddk.daniikktlsvrd...k...dsGkehklkhlkikswpdk
EGLEGEMSMDAfnyVNHRTRNNLDPIIVHSSLGTGRACAFVGAEYMFQMIN-TKKCGTARFFqVDFRTKRLGALQNGKQLF
.... . . |. |..|| | | ||. .|| | |.. |. . | ||...| | .
svalstlallr...tlrilrkasGpvvvhcsaGiGrtGtfvaievglqilldGkeldlldlv.ralrnsrlnsvqvdiqyl
|
|||||||||
| 0041856 | (Phosphotyrosine protein) phosphatases II | 439-685 | 1.4e-18 | 62.6 | In-house | 3-174 (182) | alignment | ||
Range on Protein: 439-685
Range on HMM: 3-174/182.0
KLCRDPKVQAWDSTSylvdDTHFIHASTVTapGKEYIGKAIICQAPFDDkekghpdTRESFWRMVWDTRATYVVMCCqimengvqkCGRYFPdetgaten
.. | ... .| . | ..|.|. . | . . |..|.| .. | ..|.||... . |..|... . .|.|
dknrysdilpydhsr....dldyInanlyl..gslpatrfiatqgplls.......tvadflrmlkelgittivnlt.........eelywp........
ygfaevqllekhemlnghlltrkieltsgtwkhsddDPPIRTITHFQFLKWKEGEGLEgemsMDAFNYVNHRTRNNLDPIIVHSSLGTGRACAFVGAEYM
. |.......| | .. . .| .. .. ... |..|| | | ||....|.| .|
....................................ellerlgiqylylpwpDhgvpd....ldelldfieevleeggpvlVHCsaGvgRtgtlvaaylm
FQMintkkCGTARFFQVDFRTKRLGALQNGKQLFWVQNMAFELLIKK
.. ... .| .| |. .. |.|..| ...||| |
kkl.....gvsleeavklvrsrRpgmvitpnqyfflqlallellllk
|
|||||||||
| subfamily_PTPN14_pd | Subfamily PTPN14 | 458-667 | 2.9e-18 | 60.9 | In-house | 75-281 (300) | alignment | ||
Range on Protein: 458-667
Range on HMM: 75-281/300.0
DTHFIHASTVTAPGKEYIGKAIICQAPFddkEkghpDTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDETGATENYGFAEVQLLEKHEMLNGHL
.| .| ||.. .. . |..|.| | | . ||.|||.. . .|| .. |.| .|. .|||... .. | . .. .| . .
stgyinassikvsvggkersyivaqgPl...e....ltvqdfWqmvWeqgvqlivmlteeeedgkeksfkyfPkleskkktvefgkfkvttkfsedsdsv
LTRKIELTSGTWKHSdddppiRTITHFQFLKWKEGE---GLEGEMS-MDAFNYVNHRTRNNLD------PIIVHSSLGTGRACAFVGAEYMFQMINTKKC
|....| |. ||. |.|. | . . ..| .| .. .. | ..| .. . |..|| | | ||. . .. . . ... .
ittglklkhlpskee......rtvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseveskeskPPvlvhCsaGvGrtGvlilsdlliatlehnee
GTARFFQVDFRTKRLGALQN
. |..| .|.
idikkvlarLreqrmllvqt
|
|||||||||
| subfamily_CG7180_pd | Subfamily CG7180 | 494-647 | 3.1e-18 | 60.5 | In-house | 96-255 (296) | alignment | ||
Range on Protein: 494-647
Range on HMM: 96-255/296.0
DTRESFWRMVWDTRATYVVMCCQIMENGVqKCGRYFPDETgaTENYGFAEVQLLEKHEMLNGHLLTRKIELT--SGTWKHSDDDPPIRTITHFQFLKWKE
.| ..|||.|.| . ||. .. .. .. |.| .. |.|| .|...|.... | . | |. . . | .. . . . |....||. .|.
etvdefWrlvydeeisavvvLtktfdfak.mypsywpnks..keqygeifveiveekqyanlkirtfkltkkivalteqekqvkaetRivklfqlteWel
GEGLEGE--MSMDAFNYVNHR-----TRNNLDPIIVHSSLGTGRACAFVGAEYMFQMINTKKC
.. . .. . |. ... |..|.|| |..|. ...... .... ...
edkvPlstnalielrrrvrlwrekvdedpeegPvvvvssdGasRsGvylaidanlelvekeee
|
|||||||||
| subfamily_PTPN23_pd | Subfamily PTPN23 | 492-633 | 3.7e-18 | 60.3 | In-house | 92-230 (288) | alignment | ||
Range on Protein: 492-633
Range on HMM: 92-230/288.0
HPDTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDETGATENYGFAEVQLLEKHEMlnGHLLTRKIELTSGTWKHsdddppIRTITHFQFLKWKE
. | ||.||.. .. .|| . | | .|. ||.| ..|.|...| .| | ...|. .. |...|. .. .....| |. .| |
lqstlnDFWlmvyeqkssviVmllskeelgkpkvdrYwPedkgetvkfgdlsvtlksvret..ethvervlkletldada......vksvshlqltsWpe
-GEGLEGEMSMDAFNYVNH----RTRNNLDPIIVHSSLGTGRACAFV
| | .. .. |.. . |. |..|| | | ||. .|
lGvPasPetllqfldevesayeavqrksktPlvvhCsaGvgRtgvfa
|
|||||||||
| subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 492-680 | 7e-18 | 59.6 | In-house | 101-277 (315) | alignment | ||
Range on Protein: 492-680
Range on HMM: 101-277/315.0
HPDTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDEtgateNYGFAEVQLLEKHEMLNGHLLTRKIeltSGTWKHSdddppIRTITHFQFLKWKE
. . . |||.|.. . .|| ...|. .|. .|.||. . . .. . | | | .. | . | . . ||.. ... | .
nvasvkdfwrlvfeedigkivmltnlvegekrkaekywpdk.....kviyGkitvtrkseevnteytvrtl...svvfgdn.....irevvqlhytswpd
GEGLEGEMS-MDAFNYVNHRTRNNLDPIIVHSSLGTGRACAFVGAEYMFQMINTKKCGTARFFQVDFRTKRLGALQNGKQLFWVQNMAFE
. . .. |. . |. |. .|.|| | | ||. .|. . ... ..... | | .| ...| .| .. .. .|
mgvpkytiplmnlirtvkqhhtnsvgaivvhcsaGvGrtGtfitldavldqaeaenaidvynfitgvrqnrikmvqvaeqyqfiydalle
|
|||||||||
| 0049260 | (Phosphotyrosine protein) phosphatases II | 493-676 | 7.2e-18 | 60.2 | In-house | 19-144 (152) | alignment | ||
Range on Protein: 493-676
Range on HMM: 19-144/152.0
PDTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFpdetgatenygfaevqllekhemlnghlltrkieltsgtwkhsdddppirtitHFQFLKWKEG
| | ..||||... .|..||... .|.| || .|. ....| | .
pntladfwrmlkelgittivmltellelgklkceqyi.....................................................qylhlpwpDh
EGLEGEMSMDAFNYVNHR-TRNNLDPIIVHSSLGTGRACAFVGAEYMFqmintkKCGTARFFQVDFRTKRLGALQNGKQLFWVQN
. .. .. .. . .. ... |..|| | | ||. ..| | .| . .. . .|.|| || .| ||.....
gvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpgqlrflye
|
|||||||||
| subfamily_PTPN1_pd | Subfamily PTPN1 | 458-675 | 1.9e-17 | 57.9 | In-house | 55-264 (290) | alignment | ||
Range on Protein: 458-675
Range on HMM: 55-264/290.0
DTHFIHASTVTAPGKEyiGKAIICQAPFddkekghPDTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDETGaTENYGFA----EVQLLEKHEml
|...| || | .. . . |. | |. |.| . ||.|||. .. ||| ...|.. .|| .|.| . ... . .|.|.....
dndyinaslveleeak..rsyiltqGPl.......pntvdhfWqmvWeqkskavvmlnkvvekeqikcaqywPqgee.ekellledtklkvkliseer..
NGHLLTRKIELTSgtwkhsDDDPPIRTITHFQFLKWKEGEGLEGEMSMDAFNYVNHR---TRNNLDPIIVHSSLGTGRACAFVGAEYMFQMINTKKC-G-
. . |..||. |.|.|| ...| . | .. | . . .. | ..| | | ||. .|. .. .. |. |.
ksyytvrllelen......lktqetreilhfhyttwpdfgvpespaaflkflfkvresGslssdvGpavihcsaGiGrsGtfclvdtclvliekkddlss
-TARFFQVDFRTKRLGALQNGKQLFWVQ
. .. | ||| .| .|| .
vdikkvllelrkyrlGliqtadqlrfsy
|
|||||||||
| subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 492-683 | 2e-17 | 58.0 | In-house | 96-278 (315) | alignment | ||
Range on Protein: 492-683
Range on HMM: 96-278/315.0
HPDTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDETGATENYGFAEVQLLEKHEmlNGHLLTRKIeLTsgtwKHSDDdppIRTITHFQFLKWKE
. . . |||||.....| .|| . |. || .|.||. . . ..| .|.||. . .. .||. | ..|.. ||.| ||| .| .
lkasvddfwrmvlqekvttivmvtkkqegdkikcrqywPdrkadsvefGsikvellslea..dtdgvarkl.vt....rksee...srtvtqfqftewPd
-GEGLEGEMSMDAFNYVNHRTRNNLDPIIVHSSLGTGRACAFVGAEYMFQMINTKKCGTARFFQVDFRTKRLGALQNGKQLFWVQNMAFELLI
| . . | ... ...|| | |.||. .. .. . . |. .. | .|.|| .| .. .. . | |
kGvdkqtssllklikevkadngkkefsllvhcsaGvGrtGvvisidevvaqikrtrsvdvfnfvknlrakrpylvqteeeyafiydavledll
|
|||||||||
| 0043147 | (Phosphotyrosine protein) phosphatases II | 459-676 | 3.3e-17 | 58.2 | In-house | 5-155 (172) | alignment | ||
Range on Protein: 459-676
Range on HMM: 5-155/172.0
THFIHASTVTAPGkeYIGKAIICQAPfddkekgHPDTRESFWRMVWDTRATYVVMCCQImengvqkcgryfpdetgatenygfaevqllekhemlnghll
...|.|| . . . . |..|.| . | ..||||... |..|....
sdyinasyldlyy..ipdrfiatqgp.......lrntladfwrmlkelgithivnltel.........................................
trkieltsgtwkHSDDDPPIRTITHFQFLKWKEGEGLEGEMSMDAFNYVNH-RTRNNLDPIIVHSSLGTGRACAFVGAEYMFqmintkKCGTARFFQVDF
| .. |.. ....| | . |. ......... ... |..|| | | ||....| | .| .. .. .
............lydpellerlgiqylylpwpDhgvpllellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml......lglsleeavalv
RTKRLGALQNGKQLFWVQN
|.|| || || |. ...
rekRpgavqnpsqyrflyy
|
|||||||||
| 0044763 | (Phosphotyrosine protein) phosphatases II | 459-682 | 4e-17 | 57.9 | In-house | 18-171 (178) | alignment | ||
Range on Protein: 459-682
Range on HMM: 18-171/178.0
THFIHASTVTapgkeyiGKAIICQAPFddkekghpdtrESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDETGatenygfaevqllekhemlnghll
. .|.|| .. . .....| ......... |..|.... .|.| .|| .|.|.|.|
sdyinaseil.......pglylgslpp...........addlellkelgithivnlteelelgflkcdpywpeeag........................
trkieltsgtwkhsdddppirtiTHFQFLKWKEGEGLE-GEMSMDAFNYVNHRTRNNLDPIIVHSSLGTGRACAFVGAEYMFQMintkKCgTARFFQVDF
..... . . . |. ......... .. |..|| | | ||....| | .| .. .. .. .
.......................iqylhipipDhgvpdllehflefvefieealdekggpvlVHCsaGvgRsgtlvaaylmkkl....gl.sleeaielv
RTKRLgALQNGKQLFWVQNMAFELL
| .| . .| || ... .. .||
rerRp.ivpnpgqlrqLyefelrll
|
|||||||||
| subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 460-687 | 1.2e-16 | 55.4 | In-house | 74-292 (305) | alignment | ||
Range on Protein: 460-687
Range on HMM: 74-292/305.0
HFIHASTVTAPGKEyiGKAIICQAPFDDkekghpdTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDETGATENYGFAEVQLLEKHEMLNGHLLT
..||| |..| . . | .|||... | || | .. . .. | |...| | .|| ||. . . . .. . .. | | . ..
eyihanyvstptnp..krfictqaplek.......tcadfwymclqdkveaifmlcnllekgakkcleyfaskdkdvlefeekgqkisvkfessvtlkfr
--RKIELTSGTWKHSDDDPPIRTITHFQFLKWKEGEGLEGEMSMdaFNyVNHRTRNNLDPIIVHSSLGTGRACAFVGAEYMF-QMINTKKCGTARFFQVD
| ..| | .||. . | . .... .. . ...| ||.|| | | ||. . | ||.. |... .. . .
kdakakvtetvlviegpgekarkvthyhwidwpdrgvpaadlai..le.llekarpskgpivvhcsagigrtgsvvmleyildqllagqiiedtdkilqk
FRTKRLGALQNGKQLFWVQNMAFELLIKKLK
| .| ..| .| ..| .. .. . ||
ireqrnnsiqtdaqylfvhqvilnyfrkkkl
|
|||||||||
| subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 458-645 | 2.2e-16 | 54.3 | In-house | 65-230 (281) | alignment | ||
Range on Protein: 458-645
Range on HMM: 65-230/281.0
DTHFIHASTVTAPGKEYigKAIICQAPfdDKekghpDTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDETGATENygFAEVQLLEKHEMLNGHL
| .||| . .| . |. | | | .|| ||||.|. .| .|| ||..| .|| ||| .. . . | .. . . .| |
stdyihanyirspflkr..gyiltqgp..kk.....etradfwrmiwqenttaivmlcqfletnrekcaeyfprnahcclq..fdklsvsyedstvnksl
LTRKIELTSgtwkhsddDPPIRTITHFQFLKWKEgegLEGEMSMDAFNYVNHRTRNNLDPIIVHSSLGTGRACAFVGAEYMFQMINTK
.| ...|. . | |||. . .| . . | . . . .. | | ..| | | ||. ... | .| | ..
vttrlnlsy........egetrlithwlwkewpd...wqvpessevmlkilrkirarstppvihcsagvgrsgtlmaveialqsihsh
|
|||||||||
| subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 487-683 | 1.1e-15 | 52.6 | In-house | 96-285 (297) | alignment | ||
Range on Protein: 487-683
Range on HMM: 96-285/297.0
DKEKGHPDTRESFWRMVWDTRATYVVMCCQIMEnGVQKCGRYFPDETGATenYGFAEVQLLEKHEMlNGHlLTRKIELTSGTWKHSdddppiRTITHFQF
... ..| . ||.||.| ... .|| . | . .|| ||..|.. .| .| |.|| .| .| . |..|.| | | | . .||
ttqmPmkatvadfWamvldeqvstivmlnddne.rdkkcaryWsdkgvtt..fGdvsvvllsvser.eGf.ikrelevtkgkakar......rvvkqyqf
LKWKEGEGLEGEMS---MDAFNYVNHRTRNNLD-PIIVHSSLGTGRACAFVGAEYMFQMINTKKCGTARFFQVDFRTKRLGALQNGKQLFWVQNMAFELL
..| . . . . .. . |.. .| . |..|| . | ||. .. . . .. .| . .| .| .| .| .| .. | |
veWPdkaverkdsassllklisevrkdfsqnaegPllvhclaGvGrtgvlltidsvvaeakrekevdifglvkklrqerpylvqtkeqykfvyvavleal
I
.
l
|
|||||||||
| 0051429 | (Phosphotyrosine protein) phosphatases II | 461-684 | 3.7e-15 | 51.8 | In-house | 6-227 (272) | alignment | ||
Range on Protein: 461-684
Range on HMM: 6-227/272.0
FIHASTVTAPGKEYI-GKAIICQAPFDDkekghpdTRESFWRMvWDTRATYVVMCCQIMENGVQKCGRYFP----------DETGATENYGFAEVQLLEK
|.|. | .|.. . |. . ...| . | ..|||. .. . ...|. .. .| | .|| || | |.. | .||. | ||..
yiNardvggygrvvkpgrlyrsggplpl.......taadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllse
HEMLNGHLLTRKIELTSGTWKHsdddppiRTITHFQFLKWKEGEGLEGEmSMDAFNYVNHrtrnnLDPIIVHSSLGTGRACAFVGAEYMFQMINTKKCGT
. .|. .| . ..|.... . |...|.... | . . ........ |..|| | | .| .| . .. . ..
ellldyilrellltlllsagea.......revmhlhytdwpdhgvpqea.llellellld.....ggpvlvHCsaGkdRTGtvvallllllgvsletivd
--------ARFFQVDFRTKRLGALQNGKQLFWVQNMAFELLIK
.. . | .| || |. |. .... . ||| .
dYlltnlyleeaveelraqrpgavqteeqylflyeallellrs
|
|||||||||
| subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 423-688 | 5.4e-15 | 49.6 | In-house | 37-291 (302) | alignment | ||
Range on Protein: 423-688
Range on HMM: 37-291/302.0
EFEIPIELTAMSAGNPKLCRDPKVQAWDSTSYLVD--DTHFIHASTVTAPGKEyiGKAIICQAPFDDKEkghpDTRESFWRMVWDTRATYVVMCcqIMEN
.. ...| . |.| .. ..|.. ||. .. ....||.|. | . . |. | | | | | |.|||||.. . . ||. ..|.
tmkvdlekCkafkknlkknqsedvpildsnlvkleaepdsyvnaskvevPelt..rsiilaQlpkvdse....dsveeFWrmvfqekivsvvil..vgee
GVQK-CGRYFPDETGATENYGFAEVQLlEKHEMLNGHLLTRKIELTSGTWKHSdddpPIRTITHFQFlkWKEGEGLEGE-MSMDAFNYVNHRTRNNLDPI
..| .|| ..|. ..|| | | | ... ||. | .. ....... ||. .... . . | ... . ...
elkktlselfpkksgdykeygkmfvNn.rkVekaeeektryviEvlPegcsns....vlanvyvltn..Wkqkkvpvkyaeliktaakvfakkikadent
IVHSSLGTGRACAFVGAEYMFQMINTKKCGTARFFQVDFRTKRLGALQNGKQLFWVQNMAFELLIKKLKM
.. | |.||| ||. . .. ....| . |..| |... || . .. .. ||..
vivSknGaGRagafltlavaveklqkgkepnikeivksiRsqRpravdslkQyvslyialllyikkkvtk
|
|||||||||
| subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 459-688 | 1.8e-14 | 48.1 | In-house | 80-295 (305) | alignment | ||
Range on Protein: 459-688
Range on HMM: 80-295/305.0
THFIHASTVTAPGKEyiGKAIIC-QAPFDDkekghpdTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDETGATENygFAEVQLLEKHEmlNGHL
...||| | .| | .|| | |.|. | . || || . . .|| |. .| | || .|.| | . . ..|. .
sdyihanyvgcpmip..ekrficaqgpldq.......tidefwwmviqnkveqivmlcktvelgklkcaqywpaaqgekle..lksgivvenvs..gskp
LTRKIELTSGTWKHSDDDPPIRTITHFQFLKWKEGeGLEgEMSMDAFNYVNhRTRNNLDPIIVHSSLGTGRACAFVGAEYMFQMI-NTKKCGTARFFQVD
. | |. . . . .. |.|. .| . |. . ... . | ||.|| | | ||. . | ||... | . |.| .
merdaeiqitllnltysgdqkmsvrhlqwtewpdr.gvp.pckltslells.airgskvpivvhcsagigrtgtivaieyilekiaenkpcppmpelvka
FRTKRLGALQNGKQLFWVQNMAFELLIKKLKM
.| .| ..|| | .... . .. ...| |
lrdqrafsiqndvqylfihrvmlnyflekyke
|
|||||||||
| subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 497-650 | 1.8e-14 | 48.5 | In-house | 59-207 (237) | alignment | ||
Range on Protein: 497-650
Range on HMM: 59-207/237.0
ESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDeTGATENYGFAEVQLLEKHEMlNGHlLTRKIELTS-GTWKhsdddpPIRTITHFQFLKWKEGEGL
. ||.|||. . . .|| ..|. .|| .|.|. | . || | | | |. . | . |. .| | .| | .|| | .
ddfwqmvwqekcsvivmltgliegnelkchkywps.tdqpaaygvltvslkkkeef.sdy.tvrslllskrltlk......evrlihqyqftswpdrgvp
EGEMSMDAF--NYVNHRTR-NNLDPIIVHSSLGTGRACAFVGAEYMFQMINTKKCGTA
. .. | | .|. .. | |.| | | ||. |. . |.. . ||
qqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlrqakekkvvdi
|
|||||||||
| subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 492-652 | 4.1e-14 | 47.4 | In-house | 100-259 (325) | alignment | ||
Range on Protein: 492-652
Range on HMM: 100-259/325.0
HPDTRESFWRMVWDTRaTYVVMCCQIMENGVQKCGRYFPDETGATENYGFAEVQLLEKHEMlNGHlLTRKIELTSGtwkhsdDDPPIRTITHFQFLKWKE
..| . .||.| | | . ||. ....| ..| |.|.| | . ..| ||.| |. . . |.... .. |.. ||. |..
ltatindlWrlvldWr.csvvvvlneldlgkdrcavywpkemgksktfGglevklrtieei.sdy.vhrvldvkqv......kkGetrsvkqfqlqswdd
-GEGLEGEMS---MDAFNYVNHRTRN---NLDPIIVHSSLGTGRACAFVGAEYMF-QMINTKKCGTARF
| .. . |. | . ||.|| | | ||. .|. . ..|. . |
mGvqkrpatlisilqlvkavservtantkastpilvhcsaGvGrtGvfislysalakvieesrvdifgf
|
|||||||||
| subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 491-686 | 5.9e-14 | 46.2 | In-house | 99-292 (302) | alignment | ||
Range on Protein: 491-686
Range on HMM: 99-292/302.0
GHPDTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDETGATENYGFAEVQLLEKHEMLNGHLLTRKIELTSGTWKHS-DDDPPIRTITHFQFLKW
.|.| .| .. . . . || |...|.. .|| |. |. | . ..| |. .. .. |. ... | . .| . . .|. ..| |
pkkstlekhwalieqynvaivvqlcsfvedeekkcaeyysdkvggelkfgrytvktvsvktdleeftdkksfklytveiknekkkkkvkktvdilafsaw
KE-GEGLEGEMSMDAFNYVNHRTRNnldpIIVHSSLGTGRACAFVGAEYMFQMINTKKCGTARFFQVDFRTKRLGALQNGKQLFWVQNMAFELLIKKL
. | | ....| ... . .| ..|| | | ||. ..| | |. .|| . |. | ||.|. .|| .. . |..|
pdhGapkeaytaldilkfcesykkn....vlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqdeqqliylllcvtkglmeka
|
|||||||||
| subfamily_CG42327_pd | Subfamily CG42327 | 457-593 | 7.7e-14 | 46.1 | In-house | 54-175 (319) | alignment | ||
Range on Protein: 457-593
Range on HMM: 54-175/319.0
DDTHFIHASTVTAPGKEyIGKAIICQAPFDdkekghpDTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDETGATENYGFAEVQLLEKHEMLNGH
| .....|| | . . | .|.. . |. .|||.||. .. .| ... |.|...| .|.| . . .. . .... |. . .
dkdeyldasyvrGydda.pnsyiaaqvsle.......dsssdfwrtvweqqsrvivqltdlselGikvcaeylPtketldntslyGdilvtlkgrevkdr
LLTRKIELtsgtwKHSdDDPPIRTITHFQFlKWKEGE
.. . | |. |. | .||. . || | |
yaistlll.....krv.dkeesrelthywy.kwleae
|
|||||||||
| subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 493-671 | 6.9e-13 | 43.0 | In-house | 90-266 (287) | alignment | ||
Range on Protein: 493-671
Range on HMM: 90-266/287.0
PDTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDETGATENYGFaEVQLLEKhEMLNGHLLTRKIELTsgtwkHSdDDPPIRTITHFQFLKWKEG
. | .|||.|..||.. |.. . .|.. .|| .|.|. |. | ||.. .... . .| . | . . | . ...|.| ..
aatvrdfwravletrsasvitmtreveearlkcykywPerevPmrvGGy.svvlldy.dikePeygvralrli.....dl.etrearvvkqldllswPdk
EGLEGEMSMDAFN-----YV-NHRTRNNLDPIIVHSSLGTGRACAFVGAEYMFQMI-NTKKCGTARFFqVDFRTKRLGALQNGKQL
... | .. | .. |..|| . | ||. .. . .. .. . .|. . .| .| . .| ||
vlaPtavglirfvldvkqhielardasevGPlvvhddvGiGrsGillatlvlvsrledlGrvdvaavv.irlreyraalvqavvql
|
|||||||||
| 0051082 | (Phosphotyrosine protein) phosphatases II | 462-662 | 1.5e-12 | 42.8 | In-house | 6-133 (151) | alignment | ||
Range on Protein: 462-662
Range on HMM: 6-133/151.0
IHASTVTaPGkeyigkAIICQAPFDdkekghpdtreSFWRMVWDTRATYVVMCCQIMENGvqKCGRYFPDETgatenygfaevqllekhemlnghlltrk
|..| || .| .....| . |...... ...|.... .|.| .| .|.|..
infsyvt.gg......lyrsggpla...........dflellkelgiktivnlrseeerg..ycpeylpelg............................
ieltsgtwkhsdddppiRTITHFQFLKWKEGEgleG----EMSMDAFNYVNHrtrNNLDPIIVHSSLGTGRACAFVGAEYMFQMintkkcGTARFFQVDF
....|...| |.. . ......... .. |..|| | | || ..|.. | .. .. ..
.................ievlhipildwpdpg...lplsfdavleflellld...kkngpvlvHCsaGkgRTGtlvalylmllg......vsleealeey
RTKRL
| ||
rlkrp
|
|||||||||
| subfamily_egg_pd | Subfamily egg | 431-638 | 5.7e-12 | 39.9 | In-house | 34-224 (307) | alignment | ||
Range on Protein: 431-638
Range on HMM: 34-224/307.0
TAMSAGNPKLCRDPKVQAWDSTSYLVD------DTHFIHASTVTapGKEYIGKAIICQAPFDdkekghpDTRESFWRMVWDTRATYVVMCCQIMENgvQK
||.|. | . .|...|. ||. .. |||| | || . . |..|||. .| . |||||. . |.|| |. ..
taasdnnlekarskrvhckdssrvklelrrGqylddfihanrvk..Gkpllnefilaqaplk.......ntvddfwrmvfqeevqyivmltsrkes..er
CGRYFPDETGATENY--GFAEVQLLEKHEMLNGHLLTRKIELTSGTwkhsdddppiR---TITHFQFlKWKEgeglEGEMSMdAFNyVNHRTRNNLDPII
| |.| . . | ... |. .. . . |. | | . . |.| ... ... . .. | . || |..
ceyywpkaesdslvtvpGslrienlkvdskadplfrvtklklvGgd..........deerflehwqg.dvnn....ssdvys.plr.vlrklrnlskpvv
VHSSLGTGRACAFVGAEYM
|.. || .|...| .|
vqdilGvskaatlvaieia
|
|||||||||
| PTPc_DSPc_SM00012 | 580-672 | 5.7e-12 | 41.1 | In-house | 1-97 (105) | alignment | |||
Range on Protein: 580-672
Range on HMM: 1-97/105.0
TITHFQFLKWKEGEGLE-GEMSMDAFNYVNHRTRNNL--DPIIVHSSLGTGRACAFVGAEYMFQMINTKKcGTARFFQV--DFRTKRLGALQNGKQLF
|..|.....|.. . | .. ......|.. .... |..||.| | ||.. || .... |...... .. .||. .|..| |. |. | .
tvkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleket.kevdifqivkelrkqRpgmvqteeqyl
|
|||||||||
| subfamily_ptpA1_pd | Subfamily ptpA1 | 491-642 | 1.8e-11 | 38.4 | In-house | 97-256 (418) | alignment | ||
Range on Protein: 491-642
Range on HMM: 97-256/418.0
GHPDTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDETGA---------TENYGFAEVQLLEKHEMLNGHLLTRKIELTSgtwkhsddDPPIRTI
|.| ||||||. |. .|| . || || ||.|.. | | .| |.|.| . . ..||.| || . | |
plpntiadfwrmvwenrcriivmlsresencrikcdrywpeqiggeqfsiygngnevfgtysvelveviqdpereiitrnirltf........egetrdi
THFQFLKWKEGEGLEGEMSMDAFNY-VNHRT------RNNLDPIIVHSSLGTGRACAFVGAEYMFQMI
|..|. | . . . . . . . | . ||||| | | ||. .|. | |.. .
tqyqyegwpdhnipdhtqpfrqllhsitnrqnqiipssdrnvpiivhcsagvgrtgtfctavimmkkl
|
|||||||||
| 0049772 | (Phosphotyrosine protein) phosphatases II | 444-686 | 2.4e-11 | 39.4 | In-house | 53-278 (314) | alignment | ||
Range on Protein: 444-686
Range on HMM: 53-278/314.0
PKVQAWDsT-----SYLVDDTHFIHASTVTAPgkeyiGKAIICQAPfddKEkghpDTRESF----------WRMV--WDTRATYVVM-------------
.... .| . .. |... .|.|| | . | |..|.| .| | ..| |||| .| . ..||
ldilpad.nrvilpglpvsgsdyinasyvdgf.....lkfIatqgp...le....itvvdfreepvlyyngwrmvlrgdlnvrdivmsrdevladelsrL
--------CCQIMENGvqkcgryfpdetgatenygfaevqlL----------EkhemlnghlltrkieltsgTWKHSDDDPPIRTITHFQFlKWKEgEGL
.....|| . .. ....... . |..... . ..
daAlgKtpllildgng.........................neptaadlellk...................eelydpelferlgikylri.pvpD.gsa
EGEMSMDAFNYVNHRTrNNLDPIIVHSSLGTGRACAFVGAEYMFQMIntkKCgTARFFQVDFRTKRLgALQNGKQLFWVQNMAFELLIKKL
. .|.| . .. .. |..|| . | ||.. || | |. .. ... |.| || . | .. . ... |.| ...
plledfdeflefieea.dkggpvlvHCkaGkgRtgtfvvaaylmkll...gv.sleealedvrlkRp.inpnpgfieqleqyefilealle
|
|||||||||
| subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 476-633 | 4.4e-11 | 37.0 | In-house | 85-244 (301) | alignment | ||
Range on Protein: 476-633
Range on HMM: 85-244/301.0
GKAIICQAPFDDkekghpdTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDETGATENYGFAEVQLLEKHEMLNG--HLLTRKIELTSG-----T
| |. |.|.. | |||..|. . . .|| .. |. .|| .|.|. . .|..|. .|.| ... . . |. ||. .|.
kkfiaaqgpmkk.......tlvdfWrliwqekpvsivmvtnlkegtkskceqywpnseaeseefgpftvtlvneqvyPdfvirqlnvkiqdgsnngyier
WKHSDDDPPIRTITHFQFLKWKEgEGL--EGEMSMDAFNYVNHRTRN-NLDPIIVHSSLGTGRACAFV
. . | .... .| .| . .|. | . . . . | ||.. . |..|| | . .|. ..
kfkvksdksswdvlqlqvtdWpq.dGvvreprtvLqviddvihrqqkigggpvvVHCSdtVsrsGvYc
|
|||||||||
| subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 440-706 | 9.2e-11 | 36.0 | In-house | 46-297 (312) | alignment | ||
Range on Protein: 440-706
Range on HMM: 46-297/312.0
LCRDPKVQAWDSTSYLV--DDTHFIHASTVTAPGKEyiGKAIICQAPFDDkekghpdTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDETGATE
| | |..| || . . |. .||| | | . ...|.|... | ||... .| ... | ..|.| .|| .| | | .
lnrypniqcwdrgrftlagdenfyihanfvkictkp..erfvctqgplen.......tcthfwqlalslgstsiillcgfvedgsekcakyisdivgfvd
NyGFAEVQLLEKHEMLNGHLLTRKIelTSGTWKHSD-DDPPIRTITHFQFLKWKEgEGLEGemSMDAFNYVNHRTRNNLDPIIVHSSLGTGRACAFVGAE
| |. | || | | . |.|. | . |. | |. . ... |.| | | | ||. ... |
l.edhrvyteycteieiggkskdki..thrvlkvvvkatgqesklnhyqwaswpd.hgmpd..scdtalrllsavkkdkkpviahcsagvgrtgtlalie
YMFQMINTKKCGTARFFQVDFRTKRLGALQNGKQLFWVQNMAFELLIKKlkmhHLKFEMEEQWNFLKN-YS
| . . . | .| | ... | .. .|.| | | |..| .|. |.
smiaalrhprkqnvkdsfvllrkdrarsvrvfpqyvyalrcvleflysk....glykrneqewtkfketya
|
|||||||||
| subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 494-658 | 2.3e-10 | 35.0 | In-house | 15-177 (198) | alignment | ||
Range on Protein: 494-658
Range on HMM: 15-177/198.0
DTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDETGATENYGFAEVQLleKHEMLNGHLLTRKIELTSGTwkhsDDDPPIRTITHFQFLKWKEGE
.| ||.|||.| . ..|| . | |.| .| .|| | | . . ||. | | | |.|.|| |||
etladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvtt..ktittkpdytitaliltnnt....tappstreishyqftswkekt
GLEGEMSMD---AFNYVNHRTRN-NLDPIIVHSSLGTGRACAFVGAEYMFQMINTKKCGTARFFQVDFR
. . . | | .. . . |.||| | | | . || . . . | .|.| |
tpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakr
|
|||||||||
| subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 494-658 | 2.6e-10 | 34.8 | In-house | 16-178 (199) | alignment | ||
Range on Protein: 494-658
Range on HMM: 16-178/199.0
DTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDETGATENYGFAEVQLleKHEMLNGHLLTRKIELTSGTwkhsDDDPPIRTITHFQFLKWKEGE
.| ||.|||.| . ..|| . | |.| .| .|| | | . . ||. | | | |.|.|| |||
etmadfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvtt..ktittkpdytitaliltnnt....tappstreishyqftswkekt
GLEGEMSMD---AFNYVNHRTRN-NLDPIIVHSSLGTGRACAFVGAEYMFQMINTKKCGTARFFQVDFR
. . . | | .. . . |.||| | | | . || . . . | .|.| |
tpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakr
|
|||||||||
| subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 461-669 | 6e-10 | 33.2 | In-house | 81-277 (310) | alignment | ||
Range on Protein: 461-669
Range on HMM: 81-277/310.0
FIHASTVTApgkEYIGKAIIC-QAPFDdkekgHpdTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDeTGATENYGFAEVQLLE-KHEMLNghLL
.||| | . .|. ...|| | |.. | | ||||... || ... |...|.| || |.| | || || | | | .. .
yihanyvkt...nylrstficsqgplq.....h..tiidfwrmifqeraesilllckvgeegrpkcvgywps.lgvtetygcirvtnlsesseefe..ic
TRKIELTSgTWKHSDDDPPIRTITHFQFLKWKEG--EGLEGEMSMDAFNYVNHRTRNnlDPIIVHSSLGTGRACAFVGAEYMFQMINTKKCGTARFFQVD
. . |..| ...|| . |. | . . . | | .|| | | .| . | .. .. .. . | . .
nlavtfvp.dnvpvdeqpanlkelrvslikwpnwpdrgvpdekchtvpqrllaqvrh..gpcvvhcsagkdrlyvvvalklkidkldrglkvdaeevkte
FRTKRLGALQNGK
.. .|. |.
llksraiciqtel
|
|||||||||
| subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 422-680 | 7.8e-10 | 32.8 | In-house | 34-277 (439) | alignment | ||
Range on Protein: 422-680
Range on HMM: 34-277/439.0
PEFEIPIELTAMSAGNPKlCRDPKVQAWDSTSYLVDDTHFI-HASTVTApgkEYIgKAIICQAPFDDKEKGHPDTRESFWRMVWDTRATYVVMCCQIMEN
|... |.| . ..| | .| |.| | .... . |. ..| .|| | . . . . .| ..|||.|.. ... .|| ....|
pdyaciaslaaqeydqtk.nrykdvgafdhtrvtlqeipgvphshyina...nyi.kGyyddklyiatqgpkkettddfwrlviekktvtivmltnlves
GVqkcgrYFPDETgaTENYGFAEVQLLEKHEMLngHLLTRKIELtsgtWKHSDDDPPIRTITHFQFLKWKEGEGLEGEMSMDAF-NYVNH-RTRNNLDPI
|.| .. || |. . |. . | . . ... | ||. .|... | . . . | .| ... |.
yk.....ywpsda..evcygdiavrvdrnielp..nyvirgfkv....fnerdttekertvlqfhyiawpdknvpaqashvldflrainsandkeeygpv
IVHSSLGTGRACAFVGAEYMFQMINTKKCGTARFFQVDFRTKRLGALQNGKQLFWVQNMAFE
.|| | | ||. . . . .. ..... . .| .| .|. | ...| .|
vvhcsagvGrtGtiialdialeqlklenkvdikgivkvlrkqrkqmvqalcqyvfiynavle
|
|||||||||
| subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 458-591 | 1.1e-09 | 32.5 | In-house | 58-176 (297) | alignment | ||
Range on Protein: 458-591
Range on HMM: 58-176/297.0
DTHFIHASTVTAPGKEYIGKAIICQAPFDdkekghpDTRESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDETGATENYGFAEVQLLEKHEmlnGHl
.. .| | |. | .| | |. | | . .| . ||..|.. .|| ... |.| .|| |.|. . . | |. | . .
erdyinadyvvfpdeeadlkyilaqGpls.......atvddfwtlvaeqdvrvivmvaklqedGrdkcapywpsvvqerlkagdvvveflssts...de.
lTRKIELTSGTWKHSdddPPIRTITHFQFLKWKE
.. || . . | ..| ||| | .
.fdrviltelqliyr...sesrvvrhvqflswpd
|
|||||||||
| subfamily_eak_pd | Subfamily eak | 497-591 | 2.2e-09 | 31.2 | In-house | 107-191 (332) | alignment | ||
Range on Protein: 497-591
Range on HMM: 107-191/332.0
ESFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDETGATENYGFAEVQllEKHEMLNGHLLTRKIELTSGTWKHsdddppirTITHFQFLKWKE
||.|| . .. .|. . .|....| .||||.| ..|. .|. |. . .. | ||..||. | | . |... | |
fafwqmvleqkspaivqlledvelkleksdkyfpdktreelkfGildve..rkefvkrniletrllelskGneth........rvlhykvfGwte
|
|||||||||
| subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 498-671 | 2.2e-09 | 31.8 | In-house | 67-230 (239) | alignment | ||
Range on Protein: 498-671
Range on HMM: 67-230/239.0
SFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDETGateNYGFAEVQlLEKHEMLNGHLLTRKIELTSGTWKHsdddppiRTITHFQFLKWKEGeGLE-
||||.|. | .|| ..| .|| .|.|| | .| | | | |.. ... . | . | . ...| | . |.
dfwrmmwqerrcvivmltglieghkkkchqywpdsts...kycnlrvt.lrktevfadyiirtfvmsqvgqtee.......ryvyqyhftvwpdk.gvpq
-GEMSMDAFNYVNHRTRNNLDPIIVHSSLGTGRACAFVGAEYMFQMINTKKCGTARFFQVDFRTKRLGALQNGKQL
. . . . | ..| | | ||. ||. . |.. . .| . | | .| .|
yatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlrqakkqktvdifnyvkairedrphmvqtseqy
|
|||||||||
| subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 498-671 | 2.2e-09 | 31.8 | In-house | 66-229 (239) | alignment | ||
Range on Protein: 498-671
Range on HMM: 66-229/239.0
SFWRMVWDTRATYVVMCCQIMENGVQKCGRYFPDETGateNYGFAEVQlLEKHEMLNGHLLTRKIELTSGTWKHsdddppiRTITHFQFLKWKEGeGLE-
||||.|. | .|| ..| .|| .|.|| | .| | | | |.. ... . | . | . ...| | . |.
dfwrmmwqerrcvivmltglieghkkkchqywpdsts...kycnlrvt.lrktevfadyiirtfvmsqvgqtee.......ryvyqyhftvwpdk.gvpq
-GEMSMDAFNYVNHRTRNNLDPIIVHSSLGTGRACAFVGAEYMFQMINTKKCGTARFFQVDFRTKRLGALQNGKQL
. . . . | ..| | | ||. ||. . |.. . .| . | | .| .|
yatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlrqakkqktvdifnyvkairedrphmvqtseqy
|
|||||||||
| 0048076 | (Phosphotyrosine protein) phosphatases II | 571-680 | 4.7e-09 | 31.6 | In-house | 37-141 (145) | alignment | ||
Range on Protein: 571-680
Range on HMM: 37-141/145.0
HSDDDPPIRTITHFQFLKWKEGEGLEG-EMSMDAFNYVNHRTRNNlDPIIVHSSLGTGRACAFVGAEYMFQmintKKCGTARFFQVdFRTKRLGALQNGK
|. . . |.......| | . . |. ......... ... |..|| | | ||....|.| |.. ... .. .|..| || .|
tselellerlgiqylylpwpDhgvpdllellleflefieealkeg.gpvlVHCsaGvgRtgtlvaaylmll....lgvsleealel.vrsqrpgavpnpg
QLFWVQNMAFE
|| ... |
qlrflyefele
|
|||||||||
| subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 492-683 | 1.1e-08 | 28.9 | In-house | 97-237 (392) | alignment | ||
Range on Protein: 492-683
Range on HMM: 97-237/392.0
HPDTRESFWRMVWDTRATYVVMCCQIMENGvqkcgryfpdetgatenygfaevqllekhemlnghlltrkieltsgtwkhsdDDPPIRTITHFQFLKWKE
.. . . |||||.. ..| ..| .. | ||.. |.| .| .
naaslddfwrmvfqenvttiamvtklkegd....................................................kgddartvaqfhftewPd
GEGLEGEMSMDAF-NYVNHRTRNNLDPIIVHSSLGTGRACAFVGAEYMFQMINTKKCGTARFFQVDFRTKRLGALQNGKQLFWVQNMAFELLI
. . |. | . |. . |.|.| | | ||. . . . .. . | .. | || .| .| .. .| |.
kdvpkhtssllkfikevkadfGqythpliihcsagvgrtgvvisidsvvahakktrmvdvfnfvtnirrkrpymvqtkeqyafiygavledll
|
|||||||||
| 0048179 | (Phosphotyrosine protein) phosphatases II | 572-676 | 3.3e-08 | 28.9 | In-house | 40-139 (144) | alignment | ||
Range on Protein: 572-676
Range on HMM: 40-139/144.0
SDDDPPIRTITHFQFLKWKEGEGLEG-EMSMDAFNYVNHRTRNNlDPIIVHSSLGTGRACAFVGAEYMFqminTKKCGTARFFQVdFRTKRLGALQNGKQ
. . ..|.......| | . . |. ........ ... |..|| | | ||....| | |. .... .. .|..| || .| |
yepefleregiqylhlpwpDhgvpdllellleflefieealeeg.gpvlVHCsaGvgRtgtlvaaylmk....klglsleealal.vrsrrpgavpnpgq
LFWVQN
| ....
lrfLle
|
|||||||||