Gene Y5F2A.3 in Caenorhabditis elegans

Synonym: CELE_Y5F2A.3, Y5F2A.3

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family PTP
Subfamily PTP-unclassified
Protein sequence
ID Type Fasta BLAST phosphatome Note
CeleP224_AA protein Get Run
CeleP224_AA_89-289 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
0050432 (Phosphotyrosine protein) phosphatases II 92-287 1.2e-49 164.7 In-house 52-282 (308) alignment
Range on Protein: 92-287
Range on HMM: 52-282/308.0
FERTPPEEHKTYAFQANREKNRNPDFPLYDVTRVRLkteaEDEKNYINASITSCP--PCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFAIFSPDEQ--
.. .|..| .......|..||| .|.. || .||.|    ... .|||||  ...   ..||.|..|.|... .| ||.||. |.. ||  . ...|   
lsvkplleysvallpenkdkNrykdilpydhsRVkl....degsdYInAsyvdgyssklprkfIatqgPlpntvedFwrmvweqnvrvIvmLtklvengr

--LPMYFPTE-----------------------------------HGNARFITILHYPHWPKGHVAPSPKVILRGIYSLQPSDkvTKGKCLIHSAEGINR
   . |.|.|                                    |. |..|..||..|| ..| |||. .|. .  .. |    .|....|.  |..|
ekcaqYwplelgggsleygkftvtllseevlddytvrtleltnlgdgesrtvthfhytnWpdhgvPpspeilldflelvrksl..pggpivVHCsaGvGR

SMSFIAVDYIIELMFRNNTVDIPELITQLRSQRGGAL
.. |||.|...|.. ....||..|.. .||.|| |. 
tGtfialdllleqlekeggvdvfeavkklReqRpgmv

0036941 (Phosphotyrosine protein) phosphatases II 92-288 1.6e-49 164.2 In-house 23-261 (297) alignment
Range on Protein: 92-288
Range on HMM: 23-261/297.0
FERTPPEEHKTYAFQANREKNRNPDFPLYDVTRVRLkteAEDEKNYINASITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFAIFSPDEQ----
... .. . .......|.|||| .|.. || |||.|    ... .|||||  ... ..||.|..|.|... .| ||.||. | . ||  . ...|     
lpllllgslsvallpenleknRykdilpydhtRVkl...ddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqnvtvIvmltelvelgrek

LPMYFPTE------------------------------------HGNARFITILHYPHWPKGHVAPSPKVILRGIYSLQPSDKV--TKGKCLIHSAEGIN
 . |.|.|                                     |. |..|..||..||  .| .||. .|. |  ..   |    .|. |.|.  |..
caqywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrkvlkllpsggpvlVHCsaGvg

RSMSFIAVDYIIELMF---RNNTVDIPELITQLRSQRGGALP
||..|||.|......    ....|||.|.. .||.|| || .
RsgtfiaadlmlqqledklkeggvdileavkklReqRpgavq

0047943 (Phosphotyrosine protein) phosphatases II 90-288 9.6e-49 161.6 In-house 21-256 (273) alignment
Range on Protein: 90-288
Range on HMM: 21-256/273.0
SsFERTPPEEHKTYAFQANREKNRNPDFPLYDVTRVRLkteAEDEKNYINASITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFAIFSPDEQ--
  .. .|. . .......|..|||..|.. || .||.|    ... .|||||  ......||.|..|.|... .| ||.||. | . ||  . ...|   
l.lslkplltysvallpenkdknrykdilpydhsrvkl...gdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvweqnvrviVmLtelvelgr

--LPMYFPTEHG-----------------------------------NARFITILHYPHWPKGHVAPSPKVILRGIYSLQPSDKV--TKGKCLIHSAEGI
   . |.|.| |                                   . |..|..||..||  .| ||.. .|. |  ..   .    .|. ..|.  |.
ekcaqYwpleggelsltygkftvtllseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvrkalealpsngpvvVHCsaGv

NRSMSFIAVDYIIELMFRNNTVDIPELITQLRSQRGGALP
.|...|||.|...... ....||..|.. .||||| |. .
gRtgtfialdllldqlekeggvdvleavkllrsqRpgmvq

0040438 (Phosphotyrosine protein) phosphatases II 93-289 3.7e-48 159.8 In-house 28-261 (317) alignment
Range on Protein: 93-289
Range on HMM: 28-261/317.0
ERTPPEEHKTYAFQANREKNRNPDFPLYDVTRVRLKTEAED-EKNYINASITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFAIFSPDEQ----
 . .... .......|..|||.||...|| .||.|. . .| . .|||||  ..| . ||.|..|.|... .| ||.||. | . ||  . ...|     
lslkldtysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPlpntvedFwrmvweqgvtvivmLteleelgrek

LPMYFPT--------------------------------EHGNARFITILHYPHWPKGHVAPSPKVILRGIYSLQPSDKVTKGKCLIHSAEGINRSMSFI
   |.|.                                .... |..|..||..|| ..| |||. .|. .  .. . .  .|..|.|.  |..|...||
caqYwplgetltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavrealedpggpvlVHCsaGvgRtGtfi

AVDYIIELMFRNNTVDIPELITQLRSQRGGALPR
|.....|.. ....||..| . .||.||.|| . 
aaylmleqlekeggvdveeavkelreqRpgavqt

0051299 (Phosphotyrosine protein) phosphatases II 94-288 6e-48 159.1 In-house 35-270 (288) alignment
Range on Protein: 94-288
Range on HMM: 35-270/288.0
RTPPEEHKTYAFQANREKNRNPDFPLYDVTRVRLKTEAE-DEKNYINASITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFAIFSPDEQ----L
 .|. . .......|.||||..|.. || .||.|... . .. .|||||  ......||.|..|.|... .| ||.||. |.. ||  . ...|      
llpdltlsaallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyidgynlkrkfIatqgPlpntvedFWrmvweqnvrvIvmltklvelgrekc

PMYFPT------------------------------------EHGNARFITILHYPHWPKGHVAPSPKVILRGIYSLQPSDKVTKGKCLIHSAEGINRSM
. |.|.                                     .|. |..|..||..||  .| .||. .|. .  .. . . ..| ...|.  |..|..
aqYwplggsltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdspellldflrlvrkalasgggpvvVHCsaGvgRtg

SFIAVDYIIELMFRNNTVDIPELITQLRSQRGGALP
 |||.|...|.. ....||..|.. .||.|| |. .
tfialdllleqlekeggvdvleavkrlreqRpgmvq

0046845 (Phosphotyrosine protein) phosphatases II 96-287 6.5e-46 152.3 In-house 16-257 (284) alignment
Range on Protein: 96-287
Range on HMM: 16-257/284.0
PPEEHKTYAFQANREKNRNPDFPLYDVTRVRLKTEAE--DEKNYINASITSCP-----PCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFAIFSPDE--
.  . .......|..||| .|.. || .||.||.. .  .. .|||||  ...      ...|.|..|.|... .| ||.||. |.. ||  . ...|  
lllslsvallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqnvrvIVmltelveng

--QLPMYFPTE----------------------------------HGNARFITILHYPHWPKGHVAPSPKVILRGIYSLQPSDK--VTKGKCLIHSAEGI
  . . |.|.|                                   |. |..|..||..||  .| |||. .|. .  .. . .   ..|. ..|.  |.
rekcaqYwplegevltygdftvtllseevkddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrellenlpgggpivVHCsaGv

NRSMSFIAVDYIIELMFRNN---TVDIPELITQLRSQRGGAL
.|.. |||.|...|.. ...   .||..|.. .||.|| |. 
gRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmv

0039614 (Phosphotyrosine protein) phosphatases II 96-288 7.1e-46 152.4 In-house 45-273 (297) alignment
Range on Protein: 96-288
Range on HMM: 45-273/297.0
PPEeHKTYAFQANREKNRNPDFPLYDVTRVRLKTEAE--DEKNYINASITSCPPC-ERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFAIFSPDEQ---LP
.|.  .......|..||| .|.. || .||.||.| .   . .|||||  ... .  ||.|..|.|..| .| ||.||. | . ||  . ...|     .
kpd.ysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIatqgPlpetvedFwrmvweqgvtvivmLtklvelgrkca

MYFPTEHGNARFITI-----------------------------LHYPHWPKGHVAPSPKVILRGIYSLQPSDKV--TKGKCLIHSAEGINRSMSFIAVD
 |.|.| |.   .|.                             ..|..|| ..| ||....|. .  ..   .    .|..|.|.  |..|. .||| .
qywpeeggtygdftvtllkvehldgytvrtlevtnngesrtvthfqytgwpdhgvppslellleflelvrealaelpkggpvlVHCsaGvgRtGtfiaay

YIIELMFRNNTVDIPELITQLRSQRGGALP
...|.. .. .||..| . .||.||.|| .
lmleqlekeggvdvleavkelreqRpgavq

0045450 (Phosphotyrosine protein) phosphatases II 92-288 1.3e-45 151.9 In-house 39-288 (307) alignment
Range on Protein: 92-288
Range on HMM: 39-288/307.0
FERTPPEEHKTYAFQANREKNRNPDFPLYDVTRVRLKTEAE--DEKNYINASIT--------SCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFAI
.. ... |........|..||| .|...|| |||.|... .  .. .|||||          ... . ||.|..|.|..| .| ||.|.. | . ||  .
vtvfllgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydlkrkfIatqgPlpetvedFwrmlweqgvtvivml

FSPDEQ----LPMYFPTE----------------------------------HGNARFITILHYPHWPKGHVAPSPKVILRGIYSLQPSDKV--TKGKCL
 ...|      ..|.|.|                                   |. |..|..||..|| ..| ||.. .|. |  ..   .    .|..|
telvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfeelldfieevrkaleelpkggpvl

IHSAEGINRSMSFIAVDYIIELMFRNNT---VDIPELITQLRSQRGGALP
.|.  |..|...||| ....... ...|   ||..| . .||.||.|| .
VHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavq

0043336 (Phosphotyrosine protein) phosphatases II 92-288 2.4e-44 147.3 In-house 29-261 (278) alignment
Range on Protein: 92-288
Range on HMM: 29-261/278.0
FERTPPEEHKTYAFQANREKNRNPDFPLYDVTRVRLKTEAEDE-KNYINASITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFAIFSPDE----
. . .... .......|..||| .|...|| .||.|. . .|.  .|||||  ..... ||.|..|.|..| .| ||.||. . . .|  . ...|    
llsfkldtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpetvedFwrmvwelgvttivmLtelvelgrv

QLPMYFPT-------------------------------EHGNARFITILHYPHWPKGHVAPSPKVILRGIYSLQPSDKVTKGKCLIHSAEGINRSMSFI
.   |.|                                 .|. |..|..||..|| ..| .|.. .|. .  ..   .  .|. |.|.  |..|.. ||
kcaqYwpggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldflkavrealedsngpvlVHCsaGvgRTGtfi

AVDYIIELMFRNNTVDIPELITQLRSQRGGALP
|.....|.. .. .||..| . .||.||.||..
alyllleqlekeggvdleeavkelreqRpgavq

0040439 (Phosphotyrosine protein) phosphatases II 100-288 3.9e-41 136.7 In-house 3-230 (249) alignment
Range on Protein: 100-288
Range on HMM: 3-230/249.0
HKTYAFQANREKNRNPDFPLYDVTRVRLKTEAE-DEKNYINASITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFAIFSPDEQ----LPMYFPT
 ... ...|..|||.||.. || .||.|.   .    .|||||  ... . |..|..|.|..| .| ||.|.. . | ||  . |..|        |.|.
ysvallpenkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywpl

--------------------------------EHGNARFITILHYPHWPKGHVAPSPKVILRGIYSLQPSDKV--TKGKCLIHSAEGINRSMSFIAVDYI
                                ..|. | .. ..|..||  .| ||.. .|. |  ..   .   ..|..|.|.  |..|.  ||| ...
ggsleygdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylm

IELMFRNNTVDIPELITQLRSQRGGALP
.|.. ....||..| . .|||||.|| .
leqlekelgvdleeavkllrsqRpgavq

0042113 (Phosphotyrosine protein) phosphatases II 101-288 1.1e-39 131.7 In-house 2-227 (245) alignment
Range on Protein: 101-288
Range on HMM: 2-227/245.0
KTYAFQANREKNRNPDFPLYDVTRVRLKTEAEDE-KNYINASITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFAIFSPDEQ----LPMYFPT-
.......|..|||..|...|| |||.|. . .|.  .|||||  ... . .|.|..|.|..| .| ||.|.. . | .|. . ...|      . |.|. 
svallpenkdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywplg

-------------------------------EHGNARFITILHYPHWPKGHVAPSPKVILRGIYSLQPSDK-VTKGKCLIHSAEGINRSMSFIAVDYIIE
                                ..  |... .|| .|| ..|..... .|. .  ..   .   .|..|.|.  |..|.. |||.....|
esltygdftvtllseehlddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmle

LMFRNNTVDIPELITQLRSQRGGALP
.. .. .|...| . .|||||.|| .
qlekelgvsleeavkelrsqRpgavq

0045098 (Phosphotyrosine protein) phosphatases II 96-288 7.2e-39 129.2 In-house 21-256 (278) alignment
Range on Protein: 96-288
Range on HMM: 21-256/278.0
PPEEHKTYAFQANREKNRNPDFPLYDVTRVRlkteaedekNYINASITSCPpcERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFAIFSPDEQ----LPMY
.| |  .. .  |..||| .|.. || .||.         .|||||  ...   .|.|..|.|...  . ||.|.. . | ||  . .  |      ..|
ipseitpalylgnldknRykdilpydhsrVk.........dYINAsyidgy..pkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaqy

FPT------------------------------------EHGNARFITILHYPHWPKGHVAPSP--KVILRGIYSLQPSDKV-------------TKGKC
.|                                     |..  |..|.|||..|| ..| ..|  | .|. .  ..   |.              .|..
wpeggsltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpv

LIHSAEGINRSMSFIAVDYIIELMfrNNTVDIPELITQLRSQRGG-ALP
|.|   |..|.  ..|.....||.  ...||..| ...|||||.| |..
lVHCsaGvgRtGtlvaaylmlell..eggvdlleavkelrsqRpglavq

0037934 (Phosphotyrosine protein) phosphatases II 102-288 1.7e-34 114.8 In-house 4-226 (243) alignment
Range on Protein: 102-288
Range on HMM: 4-226/243.0
TYAFQANREKNRNPDFPLYDVTRVRLkteaEDeKNYINASITSCPPcerKWIVAQHPMKEYYEY----FWKMVFYQEIDVIFAIFSPD----EQLPMYFP
.. ...|..||| .|...|| .||.|    |.  .||||. . ..|   ..|. |.|..| .|     ||.|.. . |.||  . ...    |. ..|.|
iallpenlsknrysdilpydhsrvkl....eg.sdyinanliyvtp...rliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywp

------------------------------T-EHGNARFITILHYPHWPKGHVAPSPKVILRGIYSLQPS--------DKVTKGKCLIHSAEGINRSMSF
                              . . .  |... .||  || ..| .||. .|. .  ..             ..|..|.|   |..|.  .
gevtygdftvtllseehlddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtl

IAVDYIIELMfrnnTVDIPELITQLRSQRGG-ALP
|| .....|.    .||. | . .||.||.| | .
iaaylmllll....gvdleeavkllreqRpgkavq

0049772 (Phosphotyrosine protein) phosphatases II 90-288 8e-27 90.2 In-house 28-258 (314) alignment
Range on Protein: 90-288
Range on HMM: 28-258/314.0
SSFERTPPEEHKTYAFQANREKNRNPDFPLYDvTRVRLKTEAEDEKNYINASITSCPpceRKWIVAQHPMKEYYEYF----------WKMVFYQEIDVIF
 | . .|.  .... . .||.|||..|.. .| .||.|...  .  .|||||  ...   .|.|..|.|...... |          |.||......|. 
rslsvlpeltilvadlflnrdknryldilpad.nrvilpglpvsgsdyinasyvdgf...lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrd

AIF---------------------SP------DEQLPMYFP--------TEHGNARFITILHYpHWPKgHVAPSPKVILRGIYSLQPSdkVTKGKCLIHS
                         .      .|  .....         |.   . |. |.. ..|  . ||... ... .  ..     ..|. |.| 
ivmsrdevladelsrLdaAlgKtpllildgngneptaadlellkeelydpelferlgikylri.pvpD.gsaplledfdeflefieea..dkggpvlvHC

AEGINRSMSFIAVDYIIELMfrnnTVDIPELITQLRSQRGgALP
. |..|. .|....|.. |.     |.. | . ..|..|  . |
kaGkgRtgtfvvaaylmkll....gvsleealedvrlkRp.inp

DSPc_SM00195 94-196 8.5e-25 82.9 In-house 12-119 (263) alignment
Range on Protein: 94-196
Range on HMM: 12-119/263.0
RTPPEEHKTYAFQANREKNRNPDFPLYDVTRVRLKTEAE-DEKNYINASITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFAIFSPDE----QL
 |.|.| .. ....|..|||  ....|| |||.||.| . ....||||.. ... ...|.|..|.|...  | ||.||. ... .|  .....|    . 
stspketteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengkekc

PMYFPTEH
  |.| | 
drywpees

PTPc_SM00194 94-196 8.5e-25 82.9 In-house 12-119 (263) alignment
Range on Protein: 94-196
Range on HMM: 12-119/263.0
RTPPEEHKTYAFQANREKNRNPDFPLYDVTRVRLKTEAE-DEKNYINASITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFAIFSPDE----QL
 |.|.| .. ....|..|||  ....|| |||.||.| . ....||||.. ... ...|.|..|.|...  | ||.||. ... .|  .....|    . 
stspketteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengkekc

PMYFPTEH
  |.| | 
drywpees

Y_phosphatase Protein-tyrosine phosphatase 108-196 4.6e-22 73.9 Pfam-A 1-92 (235) alignment
Range on Protein: 108-196
Range on HMM: 1-92/235.0
NREKNRNPDFPLYDVTRVRLKTEAEDEKnYINASITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFAIFSPDE----QLPMYFPTEH
|..|||..|.. || |||.|| . .... ||||.. .  . ..|.|..|.|.|.  | ||.||. ... ||. . | .|    ... |.|.| 
nkkknRykdilpydktrvklkgsegpsd.YInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeee

Y_phosphatase Protein-tyrosine phosphatase 108-196 4.6e-22 73.9 In-house 1-92 (235) alignment
Range on Protein: 108-196
Range on HMM: 1-92/235.0
NREKNRNPDFPLYDVTRVRLKTEAEDEKnYINASITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFAIFSPDE----QLPMYFPTEH
|..|||..|.. || |||.|| . .... ||||.. .  . ..|.|..|.|.|.  | ||.||. ... ||. . | .|    ... |.|.| 
nkkknRykdilpydktrvklkgsegpsd.YInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeee

0041856 (Phosphotyrosine protein) phosphatases II 108-286 4.9e-22 73.8 In-house 1-153 (182) alignment
Range on Protein: 108-286
Range on HMM: 1-153/182.0
NREKNRNPDFPLYDVTRvrlkteaedEKNYINASITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFAIFspdeqLPMYFPTEHgnARFITILHY
|..||| .|.. || .|           .||||..  ..   ...|..|.|... .. |..|.  . | .|  .       ..|.|..    | .. ..|
nldknrysdilpydhsr.........dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt.....eelywpell..erlgiqyly

PHWPKGHVAPsPKVILRGIYSLQPsdkvTKGKCLIHSAEGINRSMSFIAVDyiieLMFRNNtVDIPELITQLRSQRGGA
  || ..| . .  .|. |   .      .|..|.|   |..|. ...| .    || ... |...| . ..||.| |.
lpwpDhgvpd.ldelldfieevle....eggpvlVHCsaGvgRtgtlvaay....lmkklg.vsleeavklvrsrRpgm

subfamily_Cele-PTP-4_pd Subfamily Cele-PTP-4 100-197 2.6e-18 60.5 In-house 43-143 (302) alignment
Range on Protein: 100-197
Range on HMM: 43-143/302.0
HKTYAFQANREKNRNPDFPLYDVTRVRLKTEAedeKNYINASITSCPPCERKWIVAQHPMKEYY---EYFWKMVFYQEIDVIFAIFSPDEQ---LPMYFP
 |  ||..| .||...|.|..| ..|.|..|.   ..|.||| .. | ..|. |.|| | ..     | ||.||| ..|  .. .  ..|    |  .||
ekCkafkknlkknqsedvpildsnlvkleaep...dsyvnaskvevPeltrsiilaQlpkvdsedsveeFWrmvfqekivsvvilvgeeelkktlselfp

TEHG
.. |
kksg

0036282 (Phosphotyrosine protein) phosphatases II 136-289 5.2e-18 60.8 In-house 3-155 (174) alignment
Range on Protein: 136-289
Range on HMM: 3-155/174.0
NYINASITSCPPCERKWIVAQHPMKeyyeyFWKMVFYQEIDVIFAIFSPDEQL----PMYFPT-EHGNARFITILHYPHWPKGHVAPSPKvILRGIYSLQ
.|||||  .   . ...|. |.|..     ||.|.. . | ...   .. |      . |.|.  .   |..  ..| .|| ..| .... .|. .  ..
dyinaspldlsyitprliagqgpla.....fwemlkelgittvvmlleekelglykcinywpelredlerlgiqylylpwpDhgvpdlsi.llefvkfve

PSDKV-TKGKCLIHSAEGINRSMSFIAVDYIIELMFrNNTVDIPELITQLRSQRGGALPR
   .   .|..|.|   |..|.  ..| .... ... ...||. .|. .||.||.|. ..
ealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqt

Y_phosphatase Protein-tyrosine phosphatase 199-287 1.7e-17 59.0 Pfam-A 132-220 (235) alignment
Range on Protein: 199-287
Range on HMM: 132-220/235.0
ARFITILHYPHWPKGHVAPSPKVILRGIYSLQPSDKVTKGKCLIHSAEGINRSMSFIAVDYIIELMFRNNTVDIPELITQLRSQRGGAL
 | .. ||| .||.  |  ||| .|. | ... | . ..|....|. .|..|...|.|.|...| . ....||. ... .||.|| |. 
krevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmv

Y_phosphatase Protein-tyrosine phosphatase 199-287 1.7e-17 59.0 In-house 132-220 (235) alignment
Range on Protein: 199-287
Range on HMM: 132-220/235.0
ARFITILHYPHWPKGHVAPSPKVILRGIYSLQPSDKVTKGKCLIHSAEGINRSMSFIAVDYIIELMFRNNTVDIPELITQLRSQRGGAL
 | .. ||| .||.  |  ||| .|. | ... | . ..|....|. .|..|...|.|.|...| . ....||. ... .||.|| |. 
krevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmv

0043147 (Phosphotyrosine protein) phosphatases II 133-288 3.2e-17 58.2 In-house 3-145 (172) alignment
Range on Protein: 133-288
Range on HMM: 3-145/172.0
DEKNYINASITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFAIFSPdeqlpmyFPTEHGNARFITILHYPHWPKGHVApSPKVILRGIYSLQP-
.  .|||||  ... . ...|. | |. .... ||.|.  . |..|. . .        . .  .  |..  ..|  || ..|  .....|. .  ..  
egsdyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltel.......lydpellerlgiqylylpwpDhgvp.llellleflefidel

SDKVTKGKCLIHSAEGINRSMSFIAVDYIIelmfrnNTVDIPELITQLRSQRGGALP
  .  .|..|.|   |..|.  ..| ....        ... | . ..|..|.|| .
lalspggpvlVHCsaGvgRtgtlvaaylml......lglsleeavalvrekRpgavq

subfamily_PTPRD_pd Subfamily PTPRD 92-198 1.3e-16 55.3 In-house 32-142 (564) alignment
Range on Protein: 92-198
Range on HMM: 32-142/564.0
FERTPPEEHKTYAFQANREKNRNPDFPLYDVTRVRLK-TEAEDEKNYINASITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFAIFSPDEQ---
.|. . .. .. . .||..|||  .   || .||.|. .|.... .|||||       ....| .|.|..|  | ||.||. |.. .|  . .  |.   
ieegqqftweaankpaNkaKNRyanivaYdhsRVvLskvegdegsDYINAsfidgyrkrkayIAtqgPlaetiedFWRmvweqnsstiVmltkleEkgkv

-LPMYFPTEHgN
 . .|.|... .
kchkYWPekg.t

subfamily_Anemone-PTP-2_pd Subfamily Anemone-PTP-2 97-196 1.5e-16 55.5 In-house 45-149 (298) alignment
Range on Protein: 97-196
Range on HMM: 45-149/298.0
PEEHKTYAFQANREKNRNPDFPLYDVTRVRLKT-EAEDEKNYINASITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFAIFSPDE----QLPMY
 ||..    ..|..||| .|   .| .||.|.. .|..| .|||||  .    .  .|..|.|..|  | ||.||  ..| .|  . .  |    . . |
eeekevarkpenkkkNRyadiialdssRvvLekedadeesdYiNAsflhaykgrnafiatqaPltetvedFWrmvteedigtiVmltnleeldktkyhky

FPTEH
.|.|.
wPdeg

subfamily_Urchin-PTP-4_pd Subfamily Urchin-PTP-4 106-283 1.9e-16 54.5 In-house 43-215 (392) alignment
Range on Protein: 106-283
Range on HMM: 43-215/392.0
QANREKNRNPDFPLYDVTRVRL-KTEAEDEKNYINASITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFAIFSPDEQLpmyfptEHGNARFITI
. | .|||  .   || .||.|   .   ...|.|||   .  .|. .| .| |     . ||.||| ...  |  .   .|           .|| .. 
einlkknryknilpydsarvkleviddipdsdylnasyipsfdnekayiasqgpnaaslddfwrmvfqenvttiamvtklkegd......kgddartvaq

LHYPHWPKGHVAPSPKVILRGIYSLQPSDKVTKGKCLIHSAEGINRSMSFIAVDYIIELMFRNNTVDIPELITQLRSQR
 |.  ||   |      .|. |  ..          .|| . |. |.   |..| ..    .   ||. ...|..| .|
fhftewPdkdvpkhtssllkfikevkadfGqythpliihcsagvgrtgvvisidsvvahakktrmvdvfnfvtnirrkr

subfamily_PTPN14_pd Subfamily PTPN14 100-183 2.1e-15 51.5 In-house 41-126 (300) alignment
Range on Protein: 100-183
Range on HMM: 41-126/300.0
HKTYAFQANREKNRNPDFPLYDVTRVRLKTEAEDEKNYINASITSCP--PCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFAIFS
 .| . . | |||| .|.  |. .||.|..  |....|||||  . .    ||..|||| |..   . ||.||. |....|  . .
lstaklpenaeknrfkdvlPyednrvelsptkenstgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivmlte

subfamily_PTPN23_pd Subfamily PTPN23 104-199 3.1e-15 50.8 In-house 39-136 (288) alignment
Range on Protein: 104-199
Range on HMM: 39-136/288.0
AFQANREKNRNPDFPLYDVTRVRLKTEAEDeknYINAS-ITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFAIFSPDEQLPM----YFPTEHGN
. . . ||||. |   || .|| |. . .|   ||||| . .  |   ..|..| |...    ||.||. |   ||  . |..|.       |.|...|.
iaklyseknrsrdilPyDhnRvklrgskDD...YinAsfvkdlspgcPdfiatqaPlqstlnDFWlmvyeqkssviVmllskeelgkpkvdrYwPedkge

A
.
t

DSPc_SM00195 197-286 3.5e-15 51.4 In-house 155-244 (263) alignment
Range on Protein: 197-286
Range on HMM: 155-244/263.0
GNARFITILHYPHWPKGHVAPSPKVILRGIYSLQPSDKVTKGKCLIHSAEGINRSMSFIAVDYIIELMFRNNTVDIPELITQLRSQRGGA
 ..|..| ..|  ||.  |  |.| .|. . ... | . ..| ...|.  |..|. .|...|.|.. . ....||| |....||.|| |.
eetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgm

PTPc_SM00194 197-286 3.5e-15 51.4 In-house 155-244 (263) alignment
Range on Protein: 197-286
Range on HMM: 155-244/263.0
GNARFITILHYPHWPKGHVAPSPKVILRGIYSLQPSDKVTKGKCLIHSAEGINRSMSFIAVDYIIELMFRNNTVDIPELITQLRSQRGGA
 ..|..| ..|  ||.  |  |.| .|. . ... | . ..| ...|.  |..|. .|...|.|.. . ....||| |....||.|| |.
eetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgm

subfamily_PTPRG_pd Subfamily PTPRG 106-196 3.9e-15 50.1 In-house 45-141 (563) alignment
Range on Protein: 106-196
Range on HMM: 45-141/563.0
QANREKNRNPDFPLYDVTRVRLKTEAEDEKN--YINASITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFAIFS----PDEQLPMYFPTEH
. |..|||. .   || .||.|.  .. .|.  ||||.       ....|..|.|.|.  . ||.|.. |.  .|  |        .. ..|.|...
penkrKnRylnivaydrsRvklsplpgkkkklDYinAnyidGyqkskafiatqgplkdtfddFWrmiWeqnvaiivmitnlvergrrkcdvYWPkde

PTPc_DSPc_SM00012 202-286 3.9e-15 51.3 In-house 2-89 (105) alignment
Range on Protein: 202-286
Range on HMM: 2-89/105.0
ITILHYPHWPKGHVAPSPKVILRGIYSLQPSDKVTK--GKCLIHSAEGINRSMSFIAVDYIIELMFRN-NTVDIPELITQLRSQRGGA
.. .||. ||. .|  ... ||. . ... . .  .  . ...|.  |..|.  |.|.|.... . .. ..||| ... .||.|| |.
vkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgm

subfamily_Anemone-PTP-6_pd Subfamily Anemone-PTP-6 96-183 7.8e-15 49.7 In-house 35-122 (318) alignment
Range on Protein: 96-183
Range on HMM: 35-122/318.0
PPEEHKTyAFQANREKNRNPDFPLYDVTRVRLKTE-AEDEKNYINASITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFAIFS
 . ..|.   ..|. |||  .   || |||.|..   | . .||||.       ....| || |. |  | ||.||. |.  ||  .  
tvtslks.lepvnkaknryanilaydhtrvkLqmlegeegsDyinanyidGyrrkkayiaaqaPlpetieDfWrmvWeqnsavivmltq

subfamily_Nvec-PTP-2_pd Subfamily Nvec-PTP-2 107-197 8.3e-15 49.7 In-house 8-102 (250) alignment
Range on Protein: 107-197
Range on HMM: 8-102/250.0
ANREKNRNPDFPLYDVTRVRLKTEA-EDEKNYINASITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFAIFS---PDEQLPMYFPTEHG
.|.||||  |.  .| .|| |..|  ..| .|||||       .. .|..|.|...  | ||.||. .....|  . .    ... . |.|.|. 
qnkeknryadiialdssrvvLekekgdkesdyinasflhgyderkafiatqgPlqatiedfWrmvleeksgtivmLtnLkesektyhqywPveka

0046846 (Phosphotyrosine protein) phosphatases II 136-288 9.5e-15 50.3 In-house 13-157 (176) alignment
Range on Protein: 136-288
Range on HMM: 13-157/176.0
NYINASITSCPpcerKWIVAQHPMKEYYEYFWKMVFYQEIDVIFAIFSPDEQL----PMYFPTEHG--NarfitILHYPHWPKGHVAPSpKVILRGIYSL
.||||..  ..    ..|. |.|. . .. |..|.. . |.... . .. |      | |.| ...          .. .|| ..| .. . .|. .  .
dyinanlilgs....rpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgi.....qylhlpwpDhgvpdl.elllellefi

QPSDKvTKGKCLIHSAEGINRSMSFIAVDyiieLMFRNNTVDIPELITQLRSQRG-GALP
.   |  .|. |.|   ||.|.  ..| .    |. ... ... | . ..|.||  ||..
realk.eggpvlVHCsaGigRtgtlvaay....llelekglsveealalvreqRplgavq

subfamily_Ptp69D_pd Subfamily Ptp69D 101-195 1.8e-14 48.6 In-house 41-140 (307) alignment
Range on Protein: 101-195
Range on HMM: 41-140/307.0
KTYAFQANREKNRNPDFPLYDVTRVRLK-TEAEDEKNYINASITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFAIFSP----DEQLPMYFPTE
|. . . |  ||| .|   .| |||.|| .. ... .|||||       ..|.|.|| |. .  . ||.|.  ||. .|  .       ... . |.| |
kvsekkenalknRyedikafDktRvkLkkingkedsdYinasfikgykekkkfiaaqdPveatigDfWRmiaeqevtlivmlsnlteknrkkcakYWpie





subfamily_PTPRB_pd Subfamily PTPRB 105-181 1.9e-14 48.4 In-house 48-125 (293) alignment
Range on Protein: 105-181
Range on HMM: 48-125/293.0
FQANREKNRNPDFPLYDVTRVRLK-TEAEDEKNYINASITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFAI
 ..||.|||  .   || .||.|. .. |....||||.  .   ..|..|..| |. |  . ||.||. ..  .|  .
lavnraknrytnilpydhsrvkLaalkdesgsDYinanyipgynsprefiatqGPlpetvddfWrmvwekkssiivml

subfamily_PTPN1_pd Subfamily PTPN1 103-178 2.2e-14 47.8 In-house 27-99 (290) alignment
Range on Protein: 103-178
Range on HMM: 27-99/290.0
YAFQANREKNRNPDFPLYDVTRVRLKTEAEdekNYINASITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVI
  ...||..||  |   || .|..|. .     .|||||.   .  .|..|..| |. .  ..||.||. |.   .
aklpenrnlnryrdvspydhsrikleradn...dyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskav

subfamily_Urchin-PTPRB-like_pd Subfamily Urchin-PTPRB-like 105-181 4.2e-14 47.3 In-house 44-121 (288) alignment
Range on Protein: 105-181
Range on HMM: 44-121/288.0
FQANREKNRNPDFPLYDVTRVRLKT-EAEDEKNYINASITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFAI
   | .||| ..   || .||.||  | |....|||||       ..|.| .| |. .  . ||..|. ...  |  .
lavnakknRyrnilpyDekrvklkkleeeagaDYinasyidgekkkkkyiatqgPladtvndfWelvyenktstivml

subfamily_Choan-PTP-1_pd Subfamily Choan-PTP-1 106-180 4.9e-14 47.1 In-house 39-114 (281) alignment
Range on Protein: 106-180
Range on HMM: 39-114/281.0
QANREKNRNPDFPLYDVTRVRL-KTEAEDEKNYINASITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFA
..|..|||  .   || |||.. ..|.. . .||||.  .    |...|..| |. .  . ||.||. |....|  
denvlknrYsnivaYDatrvkvtpneenkntDYinanfvpgykgekeyiatqgPvPaslvafWqmvweqkvsaivm

0049260 (Phosphotyrosine protein) phosphatases II 150-288 4.9e-14 47.8 In-house 9-134 (152) alignment
Range on Protein: 150-288
Range on HMM: 9-134/152.0
RKWIVAQHPMKEYYEYFWKMVFYQEIDVIFAIFSPDEQLPMYFPTEHgnarfitILHYPHWPKGHVAPSPKVILRGIYSLQPSDKVTKGKCLIHSAEGIN
.. | .|.|. . .. ||.|.  . |..|  . ...|    ...            ..  || ..| ... ..|  .  ..   .  .|..|.|   |..
fefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi.......qylhlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvg

RSMSFIAVDYIIelmfrnNTVDIPELITQLRSQRGGALP
|.  ..| ....      . |.. | . ..|..| || |
Rtgtlvaaylml......lgvsleeavalvrekRpgavp

subfamily_PTPRK_pd Subfamily PTPRK 104-179 1.8e-13 45.0 In-house 39-115 (314) alignment
Range on Protein: 104-179
Range on HMM: 39-115/314.0
AFQANREKNRNPDFPLYDVTRVRLKTEAED-EKNYINASITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIF
  . ||||||  |   || .||.|.|  .| . .||||...      ...||.|.|..|  . ||..|. ..   | 
kkdenreknrsgdilaydrsrvflitidgdpssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasiv

subfamily_PTPN12_pd Subfamily PTPN12 106-179 2.7e-13 44.4 In-house 38-112 (290) alignment
Range on Protein: 106-179
Range on HMM: 38-112/290.0
QANREKNRNPDFPLYDVTRVRLKTEAEDE-KNYINASITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIF
. |..|||  |   || .|| |... |.| ..||||..   .  . ..| || |. .  . ||.|...... .. 
eenvkknrykDilPydksrvelskieeeegsdYinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivv

subfamily_CG7180_pd Subfamily CG7180 107-191 3.2e-13 44.0 In-house 41-126 (296) alignment
Range on Protein: 107-191
Range on HMM: 41-126/296.0
ANREKNRNPDFPLYDVTRVRLKT-EAEDEKNYINASITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFAIFSPDEQLPMY
 ||||||...   || .|| |.. . |....||||.       ....|| . |.||  . ||..|. .||. .  .  . ..  ||
enreknrdvkvvPyDynRvvLekldGeeksdYinavyvdsflkkkeyivteapkketvdefWrlvydeeisavvvLtktfdfakmy

subfamily_PTPRD_pd Subfamily PTPRD 197-284 1.1e-12 42.4 In-house 174-261 (564) alignment
Range on Protein: 197-284
Range on HMM: 174-261/564.0
GNARFITILHYPHWPKGHVAPSPKVILRGIYSLQPSDKVTKGKCLIHSAEGINRSMSFIAVDYIIELMFRNNTVDIPELITQLRSQRG
 ..| ..  |. .||   |  |.. .|. |   . . . ..|  ..|   |. |.  ||..|...| .  ..|||| . ...||.|| 
sesreVrqFhFtsWPdhgvpesatslLdlirkvralnepdagPivVhCSaGVGRTGtfividamlerikeektvDiyqyvkalrkqRn

subfamily_PTPN9_pd Subfamily PTPN9 101-181 1.3e-12 42.4 In-house 35-116 (297) alignment
Range on Protein: 101-181
Range on HMM: 35-116/297.0
KTYAFQANREKNRNPDFPLYDVTRVRLKTEAEDE-KNYINASITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFAI
..   .|| ||||  |   || ||| |... |||  .||||. .     .. .| .| |.|. .. ||.||. ||. ||  .
lasklranleknrytdvlcydetrvvlakvdedeasdyinanfvdGykqkkafiatqGplkktvsdfWrmvWeqevlvivmt

0051429 (Phosphotyrosine protein) phosphatases II 135-288 1.4e-12 43.3 In-house 4-209 (272) alignment
Range on Protein: 135-288
Range on HMM: 4-209/272.0
KNYINASITSCPPC---ERKWIVAQHPMKEYYEYFWKMvFYQEIDVIFAIFSPDEQL----PMYFP---------------T------------------
 .||||.  . .     ... . ...|..   . ||..   . |..|. . |..|.     ..| |               |                  
sgyiNardvggygrvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseellld

------------EHGNARFITILHYPHWPKGHVAPSPkviLRGIYSLQ-PsdkvtKGKCLIHSAEGINRSMSFIAVDYIIELMFRNNTVD--------IP
              |.|| ...|||  ||  .|....   |. . .|        .|..|.| . |..|.  ..|...... . ..  ||        . 
yilrellltlllsagearevmhlhytdwpdhgvpqea...llellellld.....ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlyle

ELITQLRSQRGGALP
| . .||.|| || .
eaveelraqrpgavq

subfamily_PTPN3_pd Subfamily PTPN3 103-179 2.9e-12 41.1 In-house 36-113 (280) alignment
Range on Protein: 103-179
Range on HMM: 36-113/280.0
YAFQANREKNRNPDFPLYDVTRVRLKTEAED--EKNYINASITSCPpCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIF
    .| .|||  |   || |||.|| .  |  . ||.|  | |      ..|..| |...  . ||.||. |.. .| 
arkpenlsknryrdilpydatrvklkesetdyinanyvnmeipstg.lvnryiatqGPlaktatdfWqmvweqkssliv

0044763 (Phosphotyrosine protein) phosphatases II 152-289 4.3e-12 41.5 In-house 30-156 (178) alignment
Range on Protein: 152-289
Range on HMM: 30-156/178.0
WIVAQHPMkeyyEYFWKMVFYQEIDVIFAIFSPDEQL----PMYFPTEHGnarfITILHYpHWPKGHVAPSPKVILRGIYSLQPSDKVTKGKCLIHSAEG
 .....|.    . .....  . |..|  . ...|      . |.|.|.|    |. ||. ..| ..| .... .|. .  ..   .  .|..|.|   |
lylgslpp....addlellkelgithivnlteelelgflkcdpywpeeag....iqylhi.pipDhgvpdllehflefvefieealdekggpvlVHCsaG

INRSMSFIAVDYIIELmfrnnTVDIPELITQLRSQRGgALPR
..|| ...| .....|      ....| | ..|..|  . |.
vgRsgtlvaaylmkkl.....glsleeaielvrerRp.ivpn

subfamily_Cele-PTP-8_pd Subfamily Cele-PTP-8 101-181 5.2e-12 40.4 In-house 36-113 (288) alignment
Range on Protein: 101-181
Range on HMM: 36-113/288.0
KTYAFQANREKNRNPDFPLYDVTRVRLKteaEDEKNYINASITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFAI
   .| ||  ..|  . |  |.|||.|.   .| . ||.| . |. . .|. | || |..   | .|||.. .... |  .
iidsfianptrdryenlprcditrvkls...ddpdfyiaanvvssakykrrlicaqaPlngtieelWkmllesdveyivml

subfamily_Urchin-PTPRB-like_pd Subfamily Urchin-PTPRB-like 197-284 6.3e-12 40.1 In-house 172-259 (288) alignment
Range on Protein: 197-284
Range on HMM: 172-259/288.0
GNARFITILHYPHWPKGHVAPSPKVILRGIYSLQPSDKVTKGKCLIHSAEGINRSMSFIAVDYIIELMFRNNTVDIPELITQLRSQRG
.. . || ..|  ||   |  | . .|  .. .. ...   |. ..| ..|. |.  |||.| .|. . .....|. . ...|| || 
kteleitqyqylaWpdhgvPeskapllellrqvkvanqadtgpiivhCsaGvGrtgtFialdalidaveeedyiDvagtvaklRkqRa

subfamily_Sponge-PTP8_pd Subfamily Sponge-PTP8 105-182 7.2e-12 40.1 In-house 43-121 (305) alignment
Range on Protein: 105-182
Range on HMM: 43-121/305.0
FQANREKNRNPDFPLYDVTRVRLKTEAEDE-KNYINASITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFAIF
 .||..|||. .  |.|  |..|... ... ..|||||       . |.|||| |.|.  . ||....   . .|  . 
keankaknrlkeitlldddriiltekeslddsdyinasyvdgykrkkkyivaqgPlkntvadfWrliveekvstivmlt

subfamily_egg_pd Subfamily egg 102-196 7.6e-12 39.5 In-house 33-131 (307) alignment
Range on Protein: 102-196
Range on HMM: 33-131/307.0
TYAFQ-ANREKNRNPDFPLYDVTRVRLKTEA-EDEKNYINASITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFAIFSPD--EQLPMYFPTEH
| |..  |.|| |..  .  |..||.|. .      ..| |   .  |   ..|.|| |.|.  . ||.||| .|.. |  . |    |. . |.|  .
ttaasdnnlekarskrvhckdssrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvddfwrmvfqeevqyivmltsrkeserceyywpkae

subfamily_Sponge-PTP10_pd Subfamily Sponge-PTP10 106-182 1.1e-11 39.3 In-house 45-118 (287) alignment
Range on Protein: 106-182
Range on HMM: 45-118/287.0
QANREKNRNPDFPLYDVTRVRLKteaEDEKNYINASITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFAIF
. |..|||  ..  .|  || ||   . ...||||.       ....|.|. || .    |||..  ... .|  . 
sqnkdknRltqilvpdnyrvllk...gehpdyinavfidgykekkafiiaesPmfntarnfWkliddrnvtaivmlc

subfamily_Sponge-PTP5_pd Subfamily Sponge-PTP5 96-179 1.2e-11 39.0 In-house 21-104 (283) alignment
Range on Protein: 96-179
Range on HMM: 21-104/283.0
PPEEHKTYAFQANREKNRNPDFPLYDVTRVRLKTEAEdekNYINASITS---CPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIF
|. . .  . . |..|||| .   .|. ||.||.|..   .||||.          ..|.|.|| |...    |||||| ..|  | 
pdldadiasadenkrknrnqeivpadqwrvelksesr...dyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekitaiv

subfamily_PTPN13_pd Subfamily PTPN13 195-285 1.7e-11 39.0 In-house 161-250 (273) alignment
Range on Protein: 195-285
Range on HMM: 161-250/273.0
EHGNARFITILHYPHWPKGHVAPSPKVILRGIYSLQPSDKvTKGKCLIHSAEGINRSMSFIAVDYIIELMFRNNTVDIPELITQLRSQRGG
| |..| .. |.. .||   |  |.. .|. .  ..  ..  .|  ..| . || || ..|..| ...|. |.. .|. |.. .|| || |
esgesrevahlnfvkwPdhgvPssaaellqfvaevrrlqt.dagPivvhcsaGiGrsGtlitidvvlglierdkefdvkeivrklreqrqg

subfamily_Ptp69D_pd Subfamily Ptp69D 197-285 1.9e-11 38.6 In-house 179-267 (307) alignment
Range on Protein: 197-285
Range on HMM: 179-267/307.0
GNARFITILHYPHWPKGHVAPSPKVILRGIYSLQPSDKVTKGKCLIHSAEGINRSMSFIAVDYIIELMFRNNTVDIPELITQLRSQRGG
 . | ..  ||  |.  .|  ... .|. |. ..   |  ..  ..|   | .||  |.|.| ... .  ...||| | . .|||||  
edsrkvvqyhytgWkDskvPevargllklieqvrelyklnrsPivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnl

subfamily_Sponge-PTP1_pd Subfamily Sponge-PTP1 103-200 2e-11 38.4 In-house 28-123 (267) alignment
Range on Protein: 103-200
Range on HMM: 28-123/267.0
YAFQANREKNRNPDFPLYDVTRVRLKTEAEDeknYINASITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFAIF-SPDEQLPMYFPTEHGNAR
.  . |.|.||  |   || ||| |.|. |.   |||||   .   ....|| | |.|     |....  |.. ||  .  .  .......| . |.|.
siaeknqernrlddnlpyddtrvilrtkeee...yinasyvegyktknafivtqdplkntitdfltvihdqkvpvivlltkvftdnirlfwPPkmgqak

subfamily_PTPRK_pd Subfamily PTPRK 198-283 2.7e-11 37.9 In-house 171-256 (314) alignment
Range on Protein: 198-283
Range on HMM: 171-256/314.0
NARFITILHYPHWPKGHVAPSPKVILRGIYSLQPSDKVTKGKCLIHSAEGINRSMSFIAVDYIIELMFRNNTVDIPELITQLRSQR
. | .  ...  ||. .|  | . .|. .  .. |.. ..|. ..|   |  |.  |||.| ..... |...||. . . .|||..
eirevrqfqflgWpdhdvPvsatgllklvrrvkksqeeeaGrivvhCsaGaGrtGtfiaidivldmieregvvdvfnavktlrsrk

subfamily_PTPRA_pd Subfamily PTPRA 196-284 3.4e-11 37.6 In-house 187-275 (330) alignment
Range on Protein: 196-284
Range on HMM: 187-275/330.0
HGNARFITILHYPHWPKGHVAPSPKVILRGIYSLQPSDKVTKGKCLIHSAEGINRSMSFIAVDYIIELMFRNNTVDIPELITQLRSQRG
. ..| .. .|.  ||.  |   |. .|. .  ..  .... |   .| . |. |. .||..| ..| .  .. ||. | . .|| || 
ekksrlvrqfhftswPdvGvPfepiGmlkllkkvkklnqqsagpivvhcsaGvGrtGtfivldavlervkaerkvdvfefvkrlrlqrp

subfamily_Cele-PTP-17_pd Subfamily Cele-PTP-17 85-186 4.4e-11 36.9 In-house 15-121 (347) alignment
Range on Protein: 85-186
Range on HMM: 15-121/347.0
GFFKSSSFERTPPeEHKTYAFQANREKNRNPDFPLYDVTRVRLKTE------AEDEKNYINASITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVI
 .| .   . .|. .  .  .. . .|||  |  | | ||| |  |      |.| ..|||||      .....|..|.|. .    |||||.   .  .
tyfdenlanysps.kftsvewekslsknrskdvklidatrvvlspeksknsraddvetyinashikfdnaskeyiltqyplpdtvrdfwkmvsvtkvtqv

FAIFSPDE
 .|| | .
vtifepik

subfamily_PTPRN_pd Subfamily PTPRN 104-193 4.9e-11 36.9 In-house 52-147 (297) alignment
Range on Protein: 104-193
Range on HMM: 52-147/297.0
AFQANREKNRNPDFPLYDVTRVRLKTEAE-DEKNYINAS-ITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFAIFSPDE----QLPMYFP
  . | .|||. ..  || .||.||.||. ....||||| |.   | .  .| .| |. .    ||.||. | . || .. . .|    |   |.|
kaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplastvadfwqmvweqGvvvivnltrleeegvkqckrywp

subfamily_Urchin-PTP-7_pd Subfamily Urchin-PTP-7 107-179 8.7e-11 36.3 In-house 48-121 (315) alignment
Range on Protein: 107-179
Range on HMM: 48-121/315.0
ANREKNRNPDFPLYDVTRVRL-KTEAEDEKNYINASITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIF
 |..|||  .   || .||.|  .| ... .|.||.       .|..| || |  .  . ||..|| ..|  | 
enkqknryiniiaydksrvqlpllendphsdyvnanfidGynkkrryiaaqgpnvasvkdfwrlvfeedigkiv

subfamily_Cele-PTP-6_pd Subfamily Cele-PTP-6 94-180 1e-10 36.2 In-house 27-112 (307) alignment
Range on Protein: 94-180
Range on HMM: 27-112/307.0
RTPPEEHKTYAFQANREKNRNPDFPLYDVTRVRLKTEAEdEKNYINASITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFA
.  ||   . ||.|| .|||  | .  | .|. .|..     .|| |         .|.|.|| |...    || |.  .... .  
kktpegvtveafsantdknryqdvkcqdkgrivvkfdgl.asdyihanylgiaikpkkficaqgplentqysfwamaiqekvesvim

subfamily_Anemone-PTP-5_pd Subfamily Anemone-PTP-5 99-187 1.1e-10 36.1 In-house 39-128 (319) alignment
Range on Protein: 99-187
Range on HMM: 39-128/319.0
EHKTYAFQANREKNRNPDFPLYDVTRVRLKT-EAEDEKNYINASITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFAIFSPDEQ
. ..   . |..||| ..   || ||| |.. .  .. .|||||       ..|.| .| |...  | ||.||. .|. ..  .    |.
tfdsaskeenkkknryqnilaydrtrvvlseldgvegsdyinasfidgyqerekfiatqaPlentiedfWrmvWeeessivvmltklvek

subfamily_PTPN6_pd Subfamily PTPN6 194-286 1.2e-10 35.9 In-house 180-279 (306) alignment
Range on Protein: 194-286
Range on HMM: 180-279/306.0
TEHGNARFITILHYPHWPKGHVAPSPKVILRGIYSLQPSDKVTK----GKCLIHSAEGINRSMSFIAVDYIIELMFRN---NTVDIPELITQLRSQRGGA
......| .  .|.  ||   |  .|...|  .  ..   . ..    |  ..| ..|| |  .|| .| ...|. ..     .|| .|. ..|.|| | 
kkkkeerevfqyhfksWPdhgvpkdpgavLdfledvnrkqeeleeaeagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsgl





subfamily_PTPN12_pd Subfamily PTPN12 195-284 1.2e-10 35.8 In-house 165-257 (290) alignment
Range on Protein: 195-284
Range on HMM: 165-257/290.0
EHGNARFITILHYPHWPKGHVAPSPKVILRGIYSLQPSDKVTKGKCLIHSAEGINRSMSFIAVDYIIELMFRNNT---VDIPELITQLRSQRG
 ... | .. .|| .||   |  |.| .|. | ...   .  .   ..| . |. |    ||.||. ||. ....   .|. .|...|| || 
aqkesrkvyqfhYtaWPDhgvPssaksllelielvrelqesedaPlvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqra

subfamily_PTPN5_RR_pd Subfamily PTPN5_RR 204-286 1.5e-10 35.6 In-house 165-250 (274) alignment
Range on Protein: 204-286
Range on HMM: 165-250/274.0
ILHYPHWPKGHVAPSPKVILRGIYSLQPSDKVTK---GKCLIHSAEGINRSMSFIAVDYIIELMFRNNTVDIPELITQLRSQRGGA
   |..||  ..  ... .|. .   . | . ..   .  ..| . || |   |||..  .  . ....||. .....|| .||| 
hywytdWPdhksPddantlldlvleveesreeenaklapvvvhCsaGiGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGm

0048179 (Phosphotyrosine protein) phosphatases II 196-288 1.6e-10 36.4 In-house 48-129 (144) alignment
Range on Protein: 196-288
Range on HMM: 48-129/144.0
HgnarfITILHYPHWPKGHVAPSPKVILRGIYSLQPSDKvTKGKCLIHSAEGINRSMSFIAVDyiieLMFRNNtVDIPELITQLRSQRGGALP
.     .. ...  ||  .| .... .|. .  ..   .  .|..|.|   |..|. ...| .    ||.... ... | . ..||.| || |
e.....giqylhlpwpDhgvpdllellleflefieeale.eggpvlVHCsaGvgRtgtlvaay....lmkklg.lsleealalvrsrrpgavp

subfamily_PTPN13_pd Subfamily PTPN13 105-182 1.8e-10 35.6 In-house 34-109 (273) alignment
Range on Protein: 105-182
Range on HMM: 34-109/273.0
FQANREKNRNPDFPLYDVTRVRLKTEAEdeknYINASITSCPPCERK--WIVAQHPMKEYYEYFWKMVFYQEIDVIFAIF
 ..|..|||  .   || |||.|. |.     |||||    |  . .   |..| |. |  . ||.||. |. .||  . 
kkenkdknryrnvlPydetrvklgdegg....yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamvt

subfamily_Urchin-PTPRA_pd Subfamily Urchin-PTPRA 99-195 1.9e-10 35.5 In-house 51-147 (319) alignment
Range on Protein: 99-195
Range on HMM: 51-147/319.0
EHKTYA-FQANREKNRNPDFPLYDVTRVRLK-TEAEDEKNYINASITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFAIFspDEQLPMYFPTE
  .|.|  . |..|||  .   .| ..|.|. .. |.  .|||||  .    . |.| || |...  . ||.|.. ...  |  .    ..   |.| .
adqtfanldqnkdknriinilafdknvvklerliGeefsdyinasfvtGyqrkdkyiaaqGPldntladfWrmiweyncstivllt..kdkcsqywplk

subfamily_PTPRB_pd Subfamily PTPRB 197-283 1.9e-10 35.2 In-house 176-264 (293) alignment
Range on Protein: 197-283
Range on HMM: 176-264/293.0
GNARFITILHYPHWPKGHVAPSPKVILRGIYSLQPSD--KVTKGKCLIHSAEGINRSMSFIAVDYIIELMFRNNTVDIPELITQLRSQR
 . | .. .|.  ||   |  ..| .|. .. .. .   . .|.  ..| . |. |.  |||.| ... . ....|||  ....||..|
keerkvrqyhftsWpdhgvPektktlldfvrtvreaiektaskrPivvhCsaGvGRtGtfialdrllqaieeedyvdifgivaelReeR

subfamily_Urchin-PTP-8_pd Subfamily Urchin-PTP-8 100-195 2e-10 35.6 In-house 16-111 (284) alignment
Range on Protein: 100-195
Range on HMM: 16-111/284.0
HKTYA-FQANREKNRNPDFPLYDVTRVRLKT-EAEDEKNYINASITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFAIFspDEQLPMYFPTE
 .|.|  . |..|||  .   .| ..|.|.    |.  .|||||  .    . |.| .| |...  . ||.|.. ...  |  .   ...   |.| .
dqtfanldqnkdknrighilafdknvvklerliGeefsdyinasfitGyqrkdkyiatqGPldntladfWrmiweyncstivllt..kdkcsqywplk

0048076 (Phosphotyrosine protein) phosphatases II 193-289 2.6e-10 35.7 In-house 38-128 (145) alignment
Range on Protein: 193-289
Range on HMM: 38-128/145.0
PTEHGNARFITILHYPHWPKGHVAPSPKVILRGIYSLQPSDKvTKGKCLIHSAEGINRSMSFIAVDyiieLMFRNNtVDIPELITQLRSQRGGALPR
.....  |... ..|  ||  .| .... .|. .  ..   |  .|..|.|   |..|. ...| .    ||.... |...| . ..|||| || |.
selellerlgiqylylpwpDhgvpdllellleflefieealk.eggpvlVHCsaGvgRtgtlvaay....lmlllg.vsleealelvrsqrpgavpn

subfamily_Cele-PTP-13_pd Subfamily Cele-PTP-13 96-178 2.7e-10 34.4 In-house 24-109 (281) alignment
Range on Protein: 96-178
Range on HMM: 24-109/281.0
PPEEHK-TYAFQANREKNRNPDFPLYDVTRVRLKT--EAEDEKNYINASITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVI
|| .   ..    | .|||  . |  |..||.||     ..  .|| |     |  .| .|..| | ||    ||.|.. ..   |
ppsdlctvfnqpvnnkknrylnipcldisrvqlkvkmpnknstdyihanyirspflkrgyiltqgpkketradfwrmiwqenttai

subfamily_Urchin-PTP-5_pd Subfamily Urchin-PTP-5 104-181 3.8e-10 34.4 In-house 46-123 (297) alignment
Range on Protein: 104-181
Range on HMM: 46-123/297.0
AFQ-ANREKNRNPDFPLYDVTRVRLKTEAED-EKNYINASITscPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFAI
| .  | ||.|  .   ||. ||.|.   .| . .|.|||    .  . ..|  | |||.  . ||.||. ... .|  .
aekkvnfeksRYkniLPydssRvkLaivnddpdsDyvnasfv..kgnkhrlittqmPmkatvadfWamvldeqvstivml

subfamily_Anemone-PTP-2_pd Subfamily Anemone-PTP-2 198-286 4.3e-10 34.3 In-house 183-272 (298) alignment
Range on Protein: 198-286
Range on HMM: 183-272/298.0
NARFITILHYPHWPKGHVAPSPKVILRGIYSLQPSDKVTK-GKCLIHSAEGINRSMSFIAVDYIIELMFRNNTVDIPELITQLRSQRGGA
. | .  ||. .||   |.   . .|  .   . | . ..    ... ..|..|| .|||.| ..| . ....||. . .  || .| ||
kerevrqlhftsWpdkgvpenatsvldllrkvrasqqqagnkpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpga

subfamily_Sponge-PTP11_pd Subfamily Sponge-PTP11 105-183 4.8e-10 33.8 In-house 43-124 (290) alignment
Range on Protein: 105-183
Range on HMM: 43-124/290.0
FQANREKNRNPDFPLYDVTRVRLK--TEAED-EKNYINASITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFAIFS
 . |...||  .. .||  |. |.  .. .| ...||||.       ....|..| |...    |||..  ... .|  . .
tssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgykekkqyiatqgpvsntlvdFWkliwqekvtiivmltn

subfamily_PTPN5_RR_pd Subfamily PTPN5_RR 101-197 6.1e-10 33.6 In-house 21-124 (274) alignment
Range on Protein: 101-197
Range on HMM: 21-124/274.0
KTYAFQANREKNRNPDFPLYDVTRVRLKTEAEDE--KNYINASITSCPPCERK-WIVAQHPMKEYYEYFWKMVFYQEIDVIFAIFSPDEQLP----MYFP
. .    . .|||  .    . .|| |..|  ..   .||||     .  | | .. .| |. .  . ||.|....|..||  .    |.      .|||
eeldvfgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneqkCavyfP

TEHG
....
daed

subfamily_Choan-PTP-4_pd Subfamily Choan-PTP-4 106-181 6.3e-10 33.4 In-house 31-107 (297) alignment
Range on Protein: 106-181
Range on HMM: 31-107/297.0
QANREKNRNPDFPLYDVTRVRLKTeAEDEKNYINASITSCPP--CERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFAI
..   |||  |   .| |||.|.  .  |..||||     |    . |.|.|| |...  . ||..|. |.. ||  .
nsslrknryrdilatddtrvkllr.viterdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmv

subfamily_Urchin-PTP-1_pd Subfamily Urchin-PTP-1 104-179 6.5e-10 33.3 In-house 40-116 (315) alignment
Range on Protein: 104-179
Range on HMM: 40-116/315.0
AFQANREKNRNPDFPLYDVTRVRL-KTEAEDEKNYINASITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIF
  . | .|||  .   .| .||.|   . . ...|||||      ... .| .| | |   . ||.||. ...  | 
retinfkknryknilPldsarvkleviddsPdsdyinasyiksvdddkayiasqgPlkasvddfwrmvlqekvttiv

subfamily_PTPRA_pd Subfamily PTPRA 106-178 7.7e-10 33.2 In-house 56-129 (330) alignment
Range on Protein: 106-178
Range on HMM: 56-129/330.0
QANREKNRNPDFPLYDVTRVRLKT-EAEDEKNYINASITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVI
. |.|||| ..   || .|| | . | ..| .|||||         |.| || | .|  | ||.|.. |.   |
eenkeknrvvnilPydfsrvilsvkeGveesdyinasfidGykekdkfiaaqGPkeetvedfwrmiweqksati

subfamily_Sponge-PTP8_pd Subfamily Sponge-PTP8 195-287 1e-09 33.0 In-house 173-266 (305) alignment
Range on Protein: 195-287
Range on HMM: 173-266/305.0
EHGNARFITILHYPHWPKGHVAPSPKVILRGIYSLQPSDKVTKG-KCLIHSAEGINRSMSFIAVDYIIELMFRNNTVDIPELITQLRSQRGGAL
|  . | .. ..   ||   |  ..  .|. |  .| . |  ||   |.|  .|. |.  |||||  .| . . ..||. |.. ||||.| ...
edkesrtvlqyqltdWPdhGvpqfatsllslikrvqkdqkkdkgvpllVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkmv

subfamily_Anemone-PTP-6_pd Subfamily Anemone-PTP-6 195-283 1.4e-09 32.4 In-house 170-259 (318) alignment
Range on Protein: 195-283
Range on HMM: 170-259/318.0
EHGNARFITILHYPHWPKGHVAPSPKVILRGIYSLQPSD-KVTKGKCLIHSAEGINRSMSFIAVDYIIELMFRNNTVDIPELITQLRSQR
|. . | .   ||  ||   |  |.  .|  . . .  . | ..|  ..| . |. |   ||||| ..| .  ...||. . ..|||.||
eeeesrqvrqyhytsWpdegvpesgaslldlvrqvskaqqksgagpivvhCsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqr

subfamily_Nvec-PTP-2_pd Subfamily Nvec-PTP-2 198-285 1.5e-09 32.4 In-house 135-223 (250) alignment
Range on Protein: 198-285
Range on HMM: 135-223/250.0
NARFITILHYPHWPKGHVAPSPKVILRGIYSLQPSDKV-TKGKCLIHSAEGINRSMSFIAVDYIIELMFRNNTVDIPELITQLRSQRGG
. | .  ||.  ||   |    . .|  .  .| |..   ..  ... ..|. || .|||.| ..| . ....||. ..| .|| .| .
derivrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidavlerlkkekvvdvfkvikvlrkdrph

subfamily_PTPN6_pd Subfamily PTPN6 105-181 2e-09 31.9 In-house 51-129 (306) alignment
Range on Protein: 105-181
Range on HMM: 51-129/306.0
FQANREKNRNPDFPLYDVTRVRLKTEAEDEKNYINASITS--CPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFAI
 . |.||||      .| ||| || .   ...||||.. .   .  ....| .|  ...  . ||.||. ..  ||  .
kpenkeknryknilPfDhtrvilkepsvpgsdyinanyikkevkgsdksyiatqgclettvsdFWrmvwqensrvivmt

subfamily_PTPN3_pd Subfamily PTPN3 196-284 2e-09 31.8 In-house 167-255 (280) alignment
Range on Protein: 196-284
Range on HMM: 167-255/280.0
HGNARFITILHYPHWPKGHVAPSPKVILRGIYSLQPSDKVTKGKCLIHSAEGINRSMSFIAVDYIIELMFRNNTVDIPELITQLRSQRG
  . | |. | |  ||   |  ... .|. . ...   ....   ..| . ||.|.  .|...  . |. ... | ..... ..| ||.
tkeerkilqlqylaWpdhgvPddsadflefvervrklrsgkeePvvvhCsaGigrtGvlilletalalieaaepvypldivrtmrdqra

subfamily_Cele-PTP-18_pd Subfamily Cele-PTP-18 100-182 2.1e-09 31.5 In-house 40-120 (305) alignment
Range on Protein: 100-182
Range on HMM: 40-120/305.0
HKTYAFQANREKNRNPDFPLYDVTRVRLktEAEDEKNYINASITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFAIF
 |..    ...|||  |    |  ||.|  |.   ..|| |   | |   ...| .| |...    || | . . .. || . 
mkafkeaqeagknrykdvgcldnnrvkl..egpwpheyihanyvstptnpkrfictqaplektcadfwymclqdkveaifmlc

subfamily_Sponge-PTP4_pd Subfamily Sponge-PTP4 104-187 2.1e-09 31.4 In-house 91-174 (244) alignment
Range on Protein: 104-187
Range on HMM: 91-174/244.0
AF-QANREKNRNPDFPLYDVTRVRLKTEAeDEKNYINASITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFAIFSPDEQ
||   |  |||.     .|. || |   .   . |||||.  |     ..|..|||. .    ||||.. . ..|.  . | .|.
afnpnnswknregaglpfdfnrvplskgs.mgntyinasfvgclgrtaeyiltqhpladtsmdfwkmmlerhvnvlvvlgsveee

subfamily_Anemone-PTP-5_pd Subfamily Anemone-PTP-5 198-284 2.1e-09 31.9 In-house 176-263 (319) alignment
Range on Protein: 198-284
Range on HMM: 176-263/319.0
NARFITILHYPHWPKGHVAPSPKVILRGIYSLQPSDKV-TKGKCLIHSAEGINRSMSFIAVDYIIELMFRNNTVDIPELITQLRSQRG
..| ..  .| .||   |  . . .|  .  .. | .  ..|   .| ..|. |  .||..| ..| . .....|. . . .|| || 
etRevkhfqyteWpdhdvPekatslldllkrirksrektqsgPivvhCsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRn

subfamily_Choan-PTP-3_pd Subfamily Choan-PTP-3 106-181 3.8e-09 30.8 In-house 36-111 (287) alignment
Range on Protein: 106-181
Range on HMM: 36-111/287.0
QANREKNRNPDFPLYDVTRVRLKTEAEDEKNYINASITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFAI
 |. .|||  |   .| ||| | .|.|   .||||   .    . ..|.|| |.      ||..|. ..  ..  .
laavkknryadvlPiddtrvllsaegelGsdyinanyvasytddeafiaaqgPiaatvrdfwravletrsasvitm

subfamily_Urchin-PTP-6_pd Subfamily Urchin-PTP-6 107-179 4.4e-09 30.0 In-house 42-115 (515) alignment
Range on Protein: 107-179
Range on HMM: 42-115/515.0
ANREKNRNPDFPLYDVTRVRL-KTEAEDEKNYINASITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIF
 | .|||  .   || .||.|   . . ...|.|||      ... .| .| | |   . ||..|. ...  | 
infkknryknilPydsvrvklevindnPhsdyfnasyipsfdndkayiasqgPnkasvddfWrlvlqenvttia

subfamily_PTPN1_pd Subfamily PTPN1 197-285 5e-09 30.3 In-house 159-252 (290) alignment
Range on Protein: 197-285
Range on HMM: 159-252/290.0
GNARFITILHYPHWPKGHVAPSPKVILRGIYSLQPSDKVT--KGKCLIHSAEGINRSMSFIAVDYIIELMFRNN---TVDIPELITQLRSQRGG
 ..| |.  ||  ||   |  ||   |. .. .. |  ..  .|  .|| . || || .|. || .. |. ...   .||| . . .||..| |
qetreilhfhyttwpdfgvpespaaflkflfkvresGslssdvGpavihcsaGiGrsGtfclvdtclvliekkddlssvdikkvllelrkyrlG

0051082 (Phosphotyrosine protein) phosphatases II 152-286 6.2e-09 31.1 In-house 15-135 (151) alignment
Range on Protein: 152-286
Range on HMM: 15-135/151.0
WIVAQHPMKeyyeYFWKMVFYQEIDVIFAIFSPDEQLpmY----FPTEHgnaRFITILHYPHWPKGHVAPSPKVILRGIYSLQPsdkVTKGKCLIHSAEG
 .. ..|.      |....  . |..|. . |..|    |    .| .    . .. .... ||   .  |.. .|. .  |.      .|..|.|   |
lyrsggpla....dflellkelgiktivnlrseeerg..ycpeylpelg...ievlhipildwpdpglplsfdavleflellld...kkngpvlvHCsaG

INRSMSFIAVDYIIeLMfrnntVDIPELITQLRSQRGGA
..|.  ..|.. .. |.     |.. | . ..|..|.|.
kgRTGtlvalylml.lg.....vsleealeeyrlkrpgv

subfamily_Choan-PTP-2_pd Subfamily Choan-PTP-2 196-284 6.6e-09 30.1 In-house 148-244 (270) alignment
Range on Protein: 196-284
Range on HMM: 148-244/270.0
HGNARFITILHYPHWPKGHVAPSPK------VILRGIYSLQPSDK-VTKG-KCLIHSAEGINRSMSFIAVDYIIELMFRNNTVDIPELITQLRSQRG
.|. | ..  .| .||   | ...        .|. .  .. | |   |.  .|.| ..|..|.  .||.|....|. ... ||. ..|..|| .| 
kgeerrlvHfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcsaGvgRtGtlialDiavrlLeetkkvdvlaiieelRkdRm

subfamily_Anemone-PTP-4_pd Subfamily Anemone-PTP-4 107-179 1.3e-08 29.3 In-house 2-74 (237) alignment
Range on Protein: 107-179
Range on HMM: 2-74/237.0
ANREKNRNPDFPLYDVTRVRLKTEAEDeKNYINAS-ITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIF
 |. |||  .   || .|| ||    .  .||||. . .     .|.| || |..   . ||.||. .   || 
enkiknrygnivaydhsrvvlkgagsg.sdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsviv

subfamily_Cele-PTP-4_pd Subfamily Cele-PTP-4 192-286 1.4e-08 28.5 In-house 173-267 (302) alignment
Range on Protein: 192-286
Range on HMM: 173-267/302.0
FPTEHGNARFITILHYPHWPKGHVAPSPKVILRGIYSLQPSDKVTKGKCLIHSAEGINRSMSFIAVDYIIELMFRNNTVDIPELITQLRSQRGGA
.| .  |. .... .   |.. .|  .   . . . ..  ..  .. ...| | .|. |  .|...   .| . ... . | |.....||||  |
lPegcsnsvlanvyvltnWkqkkvpvkyaeliktaakvfakkikadentvivSknGaGRagafltlavaveklqkgkepnikeivksiRsqRpra

subfamily_Sponge-PTP9_pd Subfamily Sponge-PTP9 104-179 1.8e-08 28.5 In-house 36-114 (301) alignment
Range on Protein: 104-179
Range on HMM: 36-114/301.0
AFQANREKNRNPDFPLYDVTRVRLKTEAE---DEKNYINASITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIF
  ..|.. ||. .   ||  |. ||.. .    ...|||||  .    ..|.|.|| |||.    ||.... .    | 
lseenkalnrfknitvyddnriilkpkpnldlcqreyinasyidgysekkkfiaaqgpmkktlvdfWrliwqekpvsiv

subfamily_PTPRN_pd Subfamily PTPRN 197-285 2.1e-08 28.2 In-house 184-273 (297) alignment
Range on Protein: 197-285
Range on HMM: 184-273/297.0
GNARFITILHYPHWPKGHVAPSPKVILRGIYSLQPSDKVTKGKCLIHSAEGINRSMSFIAVDYIIELMFRN-NTVDIPELITQLRSQRGG
 ..| .| .|.  ||.  | .|.| .|     .. | .      ..|. .|  |.  .|..| ... . .  . .||   .  || || |
setrtvtqfhflswpeegvPasaksllefrrkvnksyrGrscpivvhcsdGaGrtGvyilidlvlnrllkGvkeidiaatlehlrdqrpg

subfamily_Choan-PTP-1_pd Subfamily Choan-PTP-1 195-283 3.7e-08 27.8 In-house 165-255 (281) alignment
Range on Protein: 195-283
Range on HMM: 165-255/281.0
EHGNARFITILHYPHWPKGHVAPSPKVILRGIYSL-QPSDKVTKGKCLIHSAEGINRSMSFIAVDYIIELMFRN-NTVDIPELITQLRSQR
|.|..| .. |.|  ||   |  ..| .|     . . ..| ||   .|| . |. |. ..||.| ... . .. ...|. .....|| .|
esgetreveqlaytaWPdhGvPattkellefrkevlkltekktkaplvihCsaGvGrtGtyialDrlvkaveaeleeldvkavvaelrker

subfamily_Urchin-PTP-3_pd Subfamily Urchin-PTP-3 95-199 4e-08 27.8 In-house 32-143 (325) alignment
Range on Protein: 95-199
Range on HMM: 32-143/325.0
TPPEEH---KTYAFQANREKNRNPDFPLYDVTRVRLKTEAEDE-KNYINASITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFAIFS---PDEQ
.|...    |. .  .|..||| ..   .| .|| |.|  .|   .|||||          .. || |. .  . .|..|.  .  |.  .      ...
lpsddgiakkvamkpenkaknrfknvvaldksrvvletkkddpssdyinasylrddkkkdvflaaqaPltatindlWrlvldWrcsvvvvlneldlgkdr

LPMYFPTEHGNA
  .|.| | |..
cavywpkemgks

subfamily_Cele-PTP-10_pd Subfamily Cele-PTP-10 107-180 5.1e-08 26.9 In-house 54-126 (305) alignment
Range on Protein: 107-180
Range on HMM: 54-126/305.0
ANREKNRNPDFPLYDVTRVRLKTEAedEKNYINASITSCPPC-ERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFA
 .  |||  | |  | . |.|.  .    .|| |    ||   |...|.|| |. .  . || ||  . .. |  
iaitknryqdvpcqdqsavkldkps..psdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkveqivm

subfamily_Urchin-PTP-8_pd Subfamily Urchin-PTP-8 198-284 5.3e-08 27.7 In-house 147-235 (284) alignment
Range on Protein: 198-284
Range on HMM: 147-235/284.0
NARFITILHYPHWPKGHVAPSPKVILRGIYSLQP--SDKVTKGKCLIHSAEGINRSMSFIAVDYIIELMFRNNTVDIPELITQLRSQRG
. | |.  |.  ||.  |  .|  ..| .  ..   | .  . . ..| . |. |.  .|..| ... | ... ||. ... .|| || 
dirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrtgvyivldvlldrmkeekqvdvynfvrdlrqqrn

subfamily_Urchin-PTPRA_pd Subfamily Urchin-PTPRA 198-284 5.9e-08 27.4 In-house 183-271 (319) alignment
Range on Protein: 198-284
Range on HMM: 183-271/319.0
NARFITILHYPHWPKGHVAPSPKVILRGIYSLQP--SDKVTKGKCLIHSAEGINRSMSFIAVDYIIELMFRNNTVDIPELITQLRSQRG
. | ||  |.  ||.  |  .|  ..| .  ..   | .  . . ..| . |. |.  .|..| ... | ... ||. ... .|| || 
dirkitqfhflGwpdvGvpdypsdlmrlvkkvrhltskenhranivvhcsaGvGrtGvyivldvlldrmkeekqvdvynfvrdlrqqrn

subfamily_Cele-PTP-14_pd Subfamily Cele-PTP-14 104-179 6.3e-08 26.5 In-house 48-123 (310) alignment
Range on Protein: 104-179
Range on HMM: 48-123/310.0
AFQANREKNRNPDFPLYDVTRVRLKTEAEDEKNYINASITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIF
|.. .  |||  |    | .||.|| .    ..|| |           .|..| |..     ||.|.| .  . |.
aykkymhknrysdvvcldtsrvklkidksryedyihanyvktnylrstficsqgplqhtiidfwrmifqeraesil

subfamily_CG7180_pd Subfamily CG7180 197-284 7.2e-08 26.4 In-house 177-270 (296) alignment
Range on Protein: 197-284
Range on HMM: 177-270/296.0
GNARFITILHYPHWPKGHVAPSP-K----VILRG-IYSLQPSDKVTKGKCLIHSAEGINRSMSFIAVDYIIELMFRNNTVDIPELITQLRSQRG
 . | .. ...  |. ..  |.  .    .. |  ..  .  .. ..|  ...| .|  ||  ..|.|  .||. ... ||. | . .|| .| 
aetRivklfqlteWeledkvPlstnalielrrrvrlwrekvdedpeegPvvvvssdGasRsGvylaidanlelvekeeevdvFeavktlrrsRp

subfamily_eak_pd Subfamily eak 120-181 9e-08 25.9 In-house 63-124 (332) alignment
Range on Protein: 120-181
Range on HMM: 63-124/332.0
YDVTRVRLKTEAEDEKNYINASITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFAI
||   ||| .   ... |||||..  .   ||.|..  . ..   .||.||. |    |  .
ydrylvrltssqlnrlGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivql

subfamily_Cele-PTP-15_pd Subfamily Cele-PTP-15 102-180 1e-07 26.2 In-house 29-105 (285) alignment
Range on Protein: 102-180
Range on HMM: 29-105/285.0
TYAFQANREKNRNPDFPLYDVTRVRLKTEaedEKNYINASITSCPPCER-KWIVAQHPMKEYYEYFWKMVFYQEIDVIFA
  |..|| . ||  |    . ||| ||     ...|| ||    |  ..  .| .| |. |    ||.|.. ..|  .. 
ytayeanpdlnryadvrcieetrvvlknh...drdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlm

subfamily_Urchin-PTP-1_pd Subfamily Urchin-PTP-1 198-283 1.1e-07 26.0 In-house 171-256 (315) alignment
Range on Protein: 198-283
Range on HMM: 171-256/315.0
NARFITILHYPHWPKGHVAPSPKVILRGIYSLQPSDKVTKGKCLIHSAEGINRSMSFIAVDYIIELMFRNNTVDIPELITQLRSQR
. | .|  ..  ||.  |      .|. |  .. ...  .   |.| . |. |.  .|..| ... . |...||. .....||..|
esrtvtqfqftewPdkGvdkqtssllklikevkadngkkefsllvhcsaGvGrtGvvisidevvaqikrtrsvdvfnfvknlrakr

subfamily_PTPN14_pd Subfamily PTPN14 197-284 1.3e-07 25.9 In-house 180-276 (300) alignment
Range on Protein: 197-284
Range on HMM: 180-276/300.0
GNARFITILHYPHWPKGHVAPSPKVIL---RGIYSLQPSD------KVTKGKCLIHSAEGINRSMSFIAVDYIIELMFRNNTVDIPELITQLRSQRG
.. | . .| |  ||. .| . .|  |   . . |..         | .|   |.| ..|. |.   | .| .|. .  |...||.. ...|| || 
keertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseveskeskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLreqrm

subfamily_Sponge-PTP6_pd Subfamily Sponge-PTP6 199-284 1.6e-07 25.1 In-house 173-259 (439) alignment
Range on Protein: 199-284
Range on HMM: 173-259/439.0
ARFITILHYPHWPKGHVAPSPKVILRGIYSLQ-PSDKVTKGKCLIHSAEGINRSMSFIAVDYIIELMFRNNTVDIPELITQLRSQRG
 | .  .||  ||.  |      .|  . ...   ||   |  ..| . |. |. . ||.|  .| .  .| |||  ... || || 
ertvlqfhyiawpdknvpaqashvldflrainsandkeeygpvvvhcsagvGrtGtiialdialeqlklenkvdikgivkvlrkqrk

subfamily_PTPRG_pd Subfamily PTPRG 200-284 1.7e-07 24.9 In-house 183-267 (563) alignment
Range on Protein: 200-284
Range on HMM: 183-267/563.0
RFITILHYPHWPKGHVAPSPKVILRGIYSLQPSDKVTKGKCLIHSAEGINRSMSFIAVDYIIELMFRNNTVDIPELITQLRSQRG
. ..  ||..||   |  ..   |  .   . . | . |  ..|  .|. |.  .|..| ... . ..|.|.. ... ..|.|| 
klvrqyhytkWPdhgvPehslpvLifvkkssaankaeaGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRn

subfamily_Cele-PTP-7_pd Subfamily Cele-PTP-7 201-287 2.2e-07 24.6 In-house 189-271 (302) alignment
Range on Protein: 201-287
Range on HMM: 189-271/302.0
FITILHYPHWPKgHVAPSPKVILRGIYSLQPSdkvTKGKCLIHSAEGINRSMSFIAVDYIIELMFRNNTVDIPELITQLRSQRGGAL
 . ||..  ||. | ||        |     |    | . |.| ..|. |. ...|. | |.|  .... |. .... .|. | ||.
tvdilafsawpd.hGapkeaytaldilkfces...ykknvlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGav

subfamily_Choan-PTP-2_pd Subfamily Choan-PTP-2 102-178 4.2e-07 24.2 In-house 14-92 (270) alignment
Range on Protein: 102-178
Range on HMM: 14-92/270.0
TYAFQANREKNRNPDFPLYDVTRVRLKTEAEDE-KNYINASITS-CPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVI
  ..  ... ||  |     .|||||... ||.  .||||         ..|.| |. |..   . ||.|.. ..   |
lpeaargkklnRyadiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtai

subfamily_Cele-PTP-19_pd Subfamily Cele-PTP-19 199-284 4.8e-07 23.8 In-house 180-261 (301) alignment
Range on Protein: 199-284
Range on HMM: 180-261/301.0
ARFITILHYPHWPKGHVaPSPKVilrGIYSLQPSDKVTKGKCLIHSAEGINRSMSFIAVDYIIELMFRNNTVDIPELITQLRSQRG
.| .|   | .|..  | |  ..    .. |    | ..   ..| ..|| ||..||. .|.   .  ..|... | . .|| .| 
trtvthyqysewtdrgv.Pksha...elfdlmelvkksekPivvhcsaGiGrsvafigteylareveadptieltealkhlrehrw

subfamily_Sponge-PTP11_pd Subfamily Sponge-PTP11 197-286 5.1e-07 23.8 In-house 175-265 (290) alignment
Range on Protein: 197-286
Range on HMM: 175-265/290.0
GNARFITILHYPHWPKGHVAPSPKVILRGIYSLQP-SDKVTKGKCLIHSAEGINRSMSFIAVDYIIELMFRNNTVDIPELITQLRSQRGGA
|... .| ..   |..    . |. ||  |.  .    | ...  ..|  ... ||  |.|..  |. .  .  .|. ... ..|.|. | 
gakqsvtqyqitnwdstgkvtnpqtillvieemyktqrkrgntsivvHCSdtvgrsavfcaaattinkcktegvidvfqvlksqRiqkpgs

subfamily_PTPN23_pd Subfamily PTPN23 199-283 5.1e-07 23.8 In-house 170-259 (288) alignment
Range on Protein: 199-283
Range on HMM: 170-259/288.0
ARFITILHYPHWPKGHVAPSPKVILRGIYSLQPSDKVTKGKC----LIHSAEGINRSMSFIA-VDYIIELMFRNNTVDIPELITQLRSQR
 . .. |..  ||.  |  ||...|. .   . . . .. |.    ..|   |..|.  |   .  ..||  .|  .||.... .|| ||
vksvshlqltsWpelGvPasPetllqfldevesayeavqrksktPlvvhCsaGvgRtgvfalvyaavrelekgnglldiiqvvsrlreqR

subfamily_Sponge-PTP6_pd Subfamily Sponge-PTP6 104-183 8.5e-07 22.8 In-house 44-124 (439) alignment
Range on Protein: 104-183
Range on HMM: 44-124/439.0
AFQANREKNRNPDFPLYDVTRVRL-KTEAEDEKNYINASITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFAIFS
| . .. |||  |   .| ||| | ..       ||||        .. .| .| | ||  . ||..|. .    |  .  
aqeydqtknrykdvgafdhtrvtlqeipgvphshyinanyikGyyddklyiatqgpkkettddfwrlviekktvtivmltn

subfamily_Urchin-PTP-6_pd Subfamily Urchin-PTP-6 198-283 8.5e-07 22.4 In-house 170-255 (515) alignment
Range on Protein: 198-283
Range on HMM: 170-255/515.0
NARFITILHYPHWPKGHVAPSPKVILRGIYSLQPSDKVTKGKCLIHSAEGINRSMSFIAVDYIIELMFRNNTVDIPELITQLRSQR
..| .|  |.  ||.  | .  . .|. |  .. .    .   .|| . |. |   .|..| ..  .   ..||. ...|..| .|
dsrtvtqfhfteWPdkGvpkhtssllklikevkadhgqythpliihcsaGvGrtGvvisidsvvahakttrmvdvfnfvtnirqkr

subfamily_Cele-PTP-10_pd Subfamily Cele-PTP-10 202-284 8.9e-07 22.8 In-house 190-269 (305) alignment
Range on Protein: 202-284
Range on HMM: 190-269/305.0
ITILHYPHWPKGHVAPSPKVILRGIYSLQPSdkvtKGKCLIHSAEGINRSMSFIAVDYIIELMFRNNTV-DIPELITQLRSQRG
.  |.. .||   | |     |  . ... |    |   ..| . || |. . .|..||.| .  |. .  .|||.  || || 
vrhlqwtewpdrgvppckltslellsairgs....kvpivvhcsagigrtgtivaieyilekiaenkpcppmpelvkalrdqra

subfamily_Cele-PTP-19_pd Subfamily Cele-PTP-19 101-181 1.5e-06 22.1 In-house 44-121 (301) alignment
Range on Protein: 101-181
Range on HMM: 44-121/301.0
KTYAFQaNREKNRNPDFPLYDVTRVRLKTEAedEKNYINASITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFAI
..||.  ...|.| |  |    | |.. ..   ..  | |   . .   ...|..| |.|.  | || |. . ... |  .
esyayl.pkdkhryptvPckPstavevivdG..krvPihanwiptsGhphrfiatqgPlkntsedfwamlvqydvekivml

subfamily_Cele-PTP-6_pd Subfamily Cele-PTP-6 197-284 1.7e-06 22.3 In-house 173-257 (307) alignment
Range on Protein: 197-284
Range on HMM: 173-257/307.0
GNARFITILHYPHWPKGHVapsPKVILRGIYSLQPSdKVTKGKCLIHSAEGINRSMSFIAVDYIIELMFR-NNTVDIPELITQLRSQRG
...| |. | .  ||   |   |.. |  |  |.   .  .   ..| . |. || . .|. .. . |..  |  |. .|. .||||| 
qksrtiqhlqwenwpdrgv...pqinltainlleav.rydtnpvvvhcsaGvGrsGtivaislvqdkmiaGinckdmkklveelrsqrh

subfamily_Urchin-PTP-7_pd Subfamily Urchin-PTP-7 198-286 1.7e-06 22.2 In-house 173-261 (315) alignment
Range on Protein: 198-286
Range on HMM: 173-261/315.0
NARFITILHYPHWPKGHVAPSPKVILRGIYSLQPSDKVTKGKCLIHSAEGINRSMSFIAVDYIIELMFRNNTVDIPELITQLRSQRGGA
| | .  |||  ||.  |. .   ..  |   .  .. . |  ..|  .|. |. .||..| ... .  .| .|. ..||..|..| ..
nirevvqlhytswpdmgvpkytiplmnlirtvkqhhtnsvgaivvhcsaGvGrtGtfitldavldqaeaenaidvynfitgvrqnrikm

subfamily_Cele-PTP-18_pd Subfamily Cele-PTP-18 198-284 2e-06 21.8 In-house 184-267 (305) alignment
Range on Protein: 198-284
Range on HMM: 184-267/305.0
NARFITILHYPHWPKGHVAPSPKVILRgiysLQPSDKVTKGKCLIHSAEGINRSMSFIAVDYIIELMFRNNTVDIPE-LITQLRSQRG
.|| .|  |.  ||   | ..   ||     |    ...||   .| . || |. | . ..||.. ..  . ..  . .. ..| || 
karkvthyhwidwpdrgvpaadlaile....llekarpskgpivvhcsagigrtgsvvmleyildqllagqiiedtdkilqkireqrn

subfamily_Sponge-PTP-4_pd Subfamily Sponge-PTP-4 120-187 2.2e-06 22.0 In-house 5-65 (130) alignment
Range on Protein: 120-187
Range on HMM: 5-65/130.0
YDVTRVRlkteaedEKNYINASITSCPPCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFAIFSPDEQ
..|.|..       ...|||||   .    .... .|||. .    ||||.. . ..|.  . | .|.
fevsrlq.......gntyinasfvGllgrtaeylltqhpladtsmdfwkmmleryvnvlvvlgsveee

subfamily_Urchin-PTP-2_pd Subfamily Urchin-PTP-2 199-284 2.5e-06 21.1 In-house 88-174 (440) alignment
Range on Protein: 199-284
Range on HMM: 88-174/440.0
ARFITILHYPHWPKGHVAPSPKVILRGIYSLQPS-DKVTKGKCLIHSAEGINRSMSFIAVDYIIELMFRNNTVDIPELITQLRSQRG
.| .   ||  ||   |      .|. |  .. | .|. .|  |.|.. |  |.   |||| |.    |.. .||  .|  .|..| 
srtlkqyhyqgwpdkgvpkfagpvlkmiqdvnesqekagngpllvhcsagagrtgviiavdsilreakrsdqidifsfinsmrnnrp

subfamily_Sponge-PTP1_pd Subfamily Sponge-PTP1 202-285 2.8e-06 21.6 In-house 158-240 (267) alignment
Range on Protein: 202-285
Range on HMM: 158-240/267.0
ITILHYPHWpkgHVAPSPKVILRGIYSLQPSDKVTKGK--CLIHSAEGINRSMSFIAVDYIIELMFRNNTVDIPELITQLRSQRGG
.|. .| .|    .    |  |. .. .   ... .|    ... ..|. || .|. .|  .| . .....|| ... ..|||| |
vtlyyykkw...nintnnkpylkplfgilaknqlengnrPlvvacsdGvGrsGtflvidsqleraktegvsdifdflrkirsqrig

subfamily_Sponge-PTP9_pd Subfamily Sponge-PTP9 202-287 2.8e-06 21.3 In-house 190-276 (301) alignment
Range on Protein: 202-287
Range on HMM: 190-276/301.0
ITILHYPHWPKGHVAPSPKVILRGIYS-LQPSDKVTKGKCLIHSAEGINRSMSFIAVDYIIELMFRNNTVDIPELITQLRSQRGGAL
.. |.   ||.  | . |. .|. |   ..   |. .|. ..|  ... ||  ...|.  .|   ..  ||. ...  .| .. || 
vlqlqvtdWpqdGvvreprtvLqviddvihrqqkigggpvvVHCSdtVsrsGvYcsvsiglEQckaegVVdvfqvtkavrrskpgaV

subfamily_Sponge-PTP5_pd Subfamily Sponge-PTP5 226-287 2.8e-06 21.5 In-house 190-249 (283) alignment
Range on Protein: 226-287
Range on HMM: 190-249/283.0
IYSLQpsDKVTKGKCLIHSAEGINRSMSFIAVDYIIELMFRNNTVDIPELITQLRSQRGGAL
. |||   .  ||  ..| ..|| |.  |||.   .. .  .  ||... .. .| || .|.
vislq..teskkgPivvhCstgiGrtavfiaasasvkdaltesvvdvfavvkimreqrmmav

subfamily_Urchin-PTP-5_pd Subfamily Urchin-PTP-5 199-283 3.8e-06 21.2 In-house 176-263 (297) alignment
Range on Protein: 199-283
Range on HMM: 176-263/297.0
ARFITILHYPHWPKGHVAP--SPKVILRGIYSLQPS-DKVTKGKCLIHSAEGINRSMSFIAVDYIIELMFRNNTVDIPELITQLRSQR
 |..   .. .||.  |    | . .|  |  .. . .....|  |.|   |. |   ....| ..  . |...||| .|...|| .|
rrvvkqyqfveWPdkaverkdsassllklisevrkdfsqnaegPllvhclaGvGrtgvlltidsvvaeakrekevdifglvkklrqer

subfamily_Cele-PTP-20_pd Subfamily Cele-PTP-20 103-180 4.2e-06 20.6 In-house 49-124 (290) alignment
Range on Protein: 103-180
Range on HMM: 49-124/290.0
YAFQANR--EKNRNPDFPLYDVTRVRLKTEAedEKNYINASITSCppCERKWIVAQHPMKEYYEYFWKMVFYQEIDVIFA
  |..|   .|||  | .  |.||| ||     . .|. |        .  .|..| ..|.    .|.||  ... .|  
kifdkntefkknrykdvvcndktrvilkdGy..dGdyvhanyvkG..lkamfiltqGalkdtvidiwrmvlqekvaaivm

subfamily_Sponge-PTP10_pd Subfamily Sponge-PTP10 197-285 4.2e-06 21.0 In-house 170-259 (287) alignment
Range on Protein: 197-285
Range on HMM: 170-259/287.0
GNARFITILHYPHWPKGHVAPSPKVILRGIYS-LQPSDKVTKGKCLIHSAEGINRSMSFIAVDYIIELMFRNNTVDIPELITQLRSQRGG
|. . ..  ..  |..    ..|. ||  |    .   | ...  ..| .... ||  |.|..  |.   .. ..|. ... . | |. |
gdkqqvkqyqitnWdstgkvtepqtillvieemyktqrkrgntsivvhCsdtvGrsamfcaaattinkckteGviDvfqvlksqriqkpg

subfamily_Cele-PTP-12_pd Subfamily Cele-PTP-12 104-185 4.8e-06 20.3 In-house 30-111 (332) alignment
Range on Protein: 104-185
Range on HMM: 30-111/332.0
AFQANREKNRNPDFPLYDVTRVRLKTEaEDEKNYINASITSCPPCERKWIVAQHPMKEYYEY-FWKMVFYQEIDVIFAIFSPD
 |  | . || | .  .| .|| |  . . . .. |||       .  .|.|| |.... || ||.||  ..  .|. .   |
kflnnmdmnriphlycfdhsrvelapq.dgkddfynaswvdgyskksayifaqapfndhteyvfwrmvserkpsmilvfgdid

subfamily_CG42327_pd Subfamily CG42327 227-287 5.3e-06 20.3 In-house 237-298 (319) alignment
Range on Protein: 227-287
Range on HMM: 237-298/319.0
YSLQPSDKVTKGKCLIHSAEGINRSMSFIAVDYIIELMFRN-NTVDIPELITQLRSQRGGAL
 | . . .  .|   .| ..|. |.   || |  |. .  . ..||||.|. ..| .|. |.
issrsgtresqGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasav

subfamily_Cele-PTP-20_pd Subfamily Cele-PTP-20 196-285 5.7e-06 20.2 In-house 179-264 (290) alignment
Range on Protein: 196-285
Range on HMM: 179-264/290.0
HGNARFITILHYPHWPKGHVAPSPKVILRGIYSLQpsdkVTKGKCLIHSAEGINRSMSFIAVDYIIELMFRNNTVDIPELITQLRSQRGG
 |    .  |.   ||   || |   .|| ...|.     . |   .| . || |. .|.|..  ....     .|. .|.  ||  | .
sGkehklkhlkikswpdksvalstlallrtlrilr....kasGpvvvhcsaGiGrtGtfvaievglqilldGkeldlldlvralrnsrln

subfamily_PTPN9_pd Subfamily PTPN9 240-283 7.8e-06 20.1 In-house 226-269 (297) alignment
Range on Protein: 240-283
Range on HMM: 226-269/297.0
CLIHSAEGINRSMSFIAVDYIIELMFRNNTVDIPELITQLRSQR
 ..| . || |.  ||..|. .. . . .|||. | . .||.||
ivvhcsaGiGrtGtfitldiclsrleevgtvdvvetvkllrtqr

subfamily_Cele-PTP-14_pd Subfamily Cele-PTP-14 202-283 9.9e-06 19.3 In-house 192-269 (310) alignment
Range on Protein: 202-283
Range on HMM: 192-269/310.0
ITILHYPHWPKGHVaPSPKVILRGIYSLqpsDKVTKGKCLIHSAEGINRSMSFIAVDYIIELMFRNNTVDIPELITQLRSQR
......| ||   | |  |.       |    .| .| |..| . |..|    .|... |. . | . ||. |..|.|. .|
vslikwpnwpdrgv.pdekchtvpqrll...aqvrhgpcvvhcsagkdrlyvvvalklkidkldrglkvdaeevktellksr