Synonym: CELE_Y62F5A.10, Y62F5A.10
Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 126-419 | 2.4e-124 | 408.7 | In-house | 4-300 (302) | alignment | ||
Range on Protein: 126-419
Range on HMM: 4-300/302.0
SEAPVKWKAEDVAVAYIGKLDASQTRPEYiDVCVATKANIENCTVWKKNLAKNQTDVYPILDATLVKDPAKPDSYVNMSSVIVPHCSYPILMGQIPKRGL
.|.. ||..|..|.... .||......|. . . ..|...|.|...||||.|||.. .||||..||| .|.||||||.|.| ||.....|...|.||..
eeekekWveeeeakklvksldtaevkkef.kkidtmkvdlekCkafkknlkknqsedvpildsnlvkleaepdsyvnaskvevPeltrsiilaQlpkvds
E---EEFWRAAYNEQVVMMYVLVGSEDEKY---DFFPKTTGSFLYYGEMFVNVRKVEKMDEERSRYTIEVLPNGFSNSVMMNVYVHTGWEPFGVPIRYAN
| |||||....|..|....|||.|. |. ..|||..|....||.||||.|||||..||..||.|||||.|.||||..||||.| |.. ||..||.
edsveeFWrmvfqekivsvvilvgeeelkktlselfpkksgdykeygkmfvNnrkVekaeeektryviEvlPegcsnsvlanvyvltnWkqkkvpvkyae
TTRSVVDVmnFVKSSNGSEKLLVVSKNGCGRAGFFITLGAAFCCLNDNSEPRIGEIVKAIRSQRPNAVESIKQYASLYLCLLYYIKKKITVPEGLQQKVE
.......| |.|.....|....|||||.||||.|.|| .|...|....||.| ||||.||||||.||.|.|||.|||..||.|||||.| ||. ..|.|
liktaakv..fakkikadentvivSknGaGRagafltlavaveklqkgkepnikeivksiRsqRpravdslkQyvslyialllyikkkvtkpeekkkkee
|
|||||||||
0036941 | (Phosphotyrosine protein) phosphatases II | 136-418 | 2.2e-53 | 176.9 | In-house | 1-291 (297) | alignment | ||
Range on Protein: 136-418
Range on HMM: 1-291/297.0
DVAVAYIGKLDASQTRPEYIDVCVATKANIENCTVWKKNLAKNQTDVYPILDATLVKDPAKPDSYVNMSSVIVPHCSYPILMGQIPKRGLEEEFWRAAYN
|... ....|. .. . |. ... . ... ...|| ||. ....| | || . ...|.|.| | ...... ... | |. . |.||| ..
dllkllekllflalllkefeellpllllgslsvallpenleknRykdilpydhtRVklddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvwe
EQVVMMYVLVGSEDE----KYDFFPKTTGSFLYYGEMFVNVRKVEKM-DEERSRYTIEVLPNGFSNSVMMNVYVHTGWEPFGVPIRYANTTRSVVDVMNF
..| . .|. .. . ..| ..|..|.||...|....||.. ... ..|.||...| ..| ..... .||| .||| .| . . | ..
qnvtvIvmltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrkv
VKSSNGSEKLLVVSKNGCGRAGFFITLGAAFCCLN---DNSEPRIGEIVKAIRSQRPNAVESIKQYASLYLCLLYYIKKKITVPEGLQQKV
| ...... || ...|.||.| ||.. ....|. . .. | |.|| .|.|||.||.. || || .||...||| |... |....
lkllpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallellkkkltkepllklvl
|
|||||||||
0040438 | (Phosphotyrosine protein) phosphatases II | 132-422 | 8.2e-51 | 168.5 | In-house | 2-294 (317) | alignment | ||
Range on Protein: 132-422
Range on HMM: 2-294/317.0
WKAEDVAVAYIGKLDASQTRPEYIDVCVATKAnIENCTVWKKNLAKNQTDVYPILDATLVK----DPAKPDSYVNMSSVIVPHCSYPILMGQIPKRGLEE
.. .. |. .. |.|. . . |..|.. .. ... ...| ||. ....|.. || .. ...|.|.| | .|... ... | |. . |
vldlllalldllksdftalleefedllslkld.tysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPlpntve
EFWRAAYNEQVVMMYVLVGSEDEK----YDFFPKttGSFLYYGEMFVNVRKVEKmDEERSRYTIEVLPNGFSNSVMMNVYVHTGWEPFGVPIryanTTRS
||| ....| . |. .|. . . ..| |..|.||...|.....|. ... .|.|| ..| |.|...... .||| .||| ....
dFwrmvweqgvtvivmLteleelgrekcaqYwpl..getltygdftvtllseee.lagitlrtlevedlgdsesrtvthfhytgWpdhgvpp....spdl
VVDVMNFVKSS--NGSEKLLVVSKNGCGRAGFFITLGAAFCCLNDNSEPRIGEIVKAIRSQRPNAVESIKQYASLYLCLLYYIKKKITVPEGLQQKVEDL
..| ...|... ......|| ...|.||.|.||.. ....|. . .. . |.|| .|.|||.||.. || || .||.|.|.|.| .. ..|.. |
lldfleavrealedpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleylkrkltlepaselklkll
K
|
k
|
|||||||||
0050432 | (Phosphotyrosine protein) phosphatases II | 123-410 | 3.1e-50 | 166.6 | In-house | 17-305 (308) | alignment | ||
Range on Protein: 123-410
Range on HMM: 17-305/308.0
PALSEAPVKWKAEDVAVAYIGKLDASQTRPEYIDVCVATKANIENCTVWKKNLAKNQTDVYPILDATLVKDpAKPDSYVNMSSVIVP--HCSYPILMGQI
. .. |. .|.. .. ..|| .. . |. ... . . ... ...| ||. ....| . || ....|.| | | .. ... ... |
tsilvsslklsvldllkllekaldlglleeefeellsvkplleysvallpenkdkNrykdilpydhsRVkl.degsdYInAsyvdgyssklprkfIatqg
PKRGLEEEFWRAAYNEQVVMMYVLVGSEDEK----YDFFPKTTG-SFLYYGEMFVNVRKVEKmDEERSRYTIEVLPNGFSNSVMMNVYVHTGWEPFGVPI
|. . | ||| ....| . .| .. . . ..| ..| ..|.|| ..|.....|. ... ..|.|. ..| ..| ..... .|.|. .|||
PlpntvedFwrmvweqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseev.lddytvrtleltnlgdgesrtvthfhytnWpdhgvPp
RyantTRSVVDVMNFVKSSNGSEKLLVVSKNGCGRAGFFITLGAAFCCLNDNSEPRIGEIVKAIRSQRPNAVESIKQYASLYLCLLYYIKKKITV
.....| ...|..|..... .| ...|.||.| ||.| ....|. . .. . |.|| .|.|||..|.. || || .||.|.|.|.|
s....peilldflelvrkslpggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylflyralleylklkltk
|
|||||||||
0039614 | (Phosphotyrosine protein) phosphatases II | 122-410 | 7.5e-48 | 158.9 | In-house | 6-295 (297) | alignment | ||
Range on Protein: 122-410
Range on HMM: 6-295/297.0
TPALSEAPVKWKAEDVAVAYIGKLDASQTRPEYIDVCVATKaNiENCTVWKKNLAKNQTDVYPILDATLVKDPAKPD-----SYVNMSSVIVPHC-SYPI
..|. |......|... .. ... .. . |. ... . . .. ...| ||. ....| . || ... .|.|.| | .... . .
dallesipiplsvldlllllekansktllllefeellslkp.d.ysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkf
LMGQIPKRGLEEEFWRAAYNEQVVMMYVLVGSEDE---KYDFFPKTTGsflYYGEMFVNVRKVEKmDEERSRYTIEVLPNGFSnsVMMNVYVHTGWEPFG
.. | | . | ||| ....| . | .. ....| ..| .||...|...|||. .. ..|.|| .|| | ..... .||| .|
IatqgPlpetvedFwrmvweqgvtvivmLtklvelgrkcaqywpeegg...tygdftvtllkveh.ldgytvrtlevtnnges..rtvthfqytgwpdhg
VPIRYANTTRSVVDVMNFVKSSNGSEKLLVVSKNGCGRAGFFITLGAAFCCLNDNSEPRIGEIVKAIRSQRPNAVESIKQYASLYLCLLYYIKKKITV
|| . . . |............ || ...|.||.| ||.. ....|. . .. . |.|| .|.|||.||.. || || .||...|.| |.
vppslellleflelvrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydallellkrkltl
|
|||||||||
0047943 | (Phosphotyrosine protein) phosphatases II | 144-405 | 1.6e-47 | 157.7 | In-house | 8-273 (273) | alignment | ||
Range on Protein: 144-405
Range on HMM: 8-273/273.0
KLDASQTRPEYIDVCVATKANIENCTVWKKNLAKNQTDVYPILDATLVKDPAKPDSYVNMSSVIVPHCSYPILMGQIPKRGLEEEFWRAAYNEQVVMMYV
.|. .. . |. ... .. .......|. ||. ....| . || . ....|.| | | ..... ... | |. . |.||| ....| . .
llgltllleefelllslkplltysvallpenkdknrykdilpydhsrvklgdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvweqnvrviVm
LVGSEDE----KYDFFPKTTGS-FLYYGEMFVNVRKVEKmDEERSRYTIEVLPNGFSNSVMMNVYVHTGWEPFGVPIRYANTTRSVVDVMNFVKSSNGSE
|. .. . ..| . |. .|.||...|.....|. .. .|.|. ..|...| ..... .||| .||| .. . . .|... .......
LtelvelgrekcaqYwpleggelsltygkftvtllseet.kddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvrkalealpsng
KLLVVSKNGCGRAGFFITLGAAFCCLNDNSEPRIGEIVKAIRSQRPNAVESIKQYASLYLCLLYYIK
. .| ...|.||.| ||.| ....|. . .. . |.|| .|||||..|.. || || .||.|.|
pvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyealleylk
|
|||||||||
0043336 | (Phosphotyrosine protein) phosphatases II | 130-405 | 1.6e-45 | 151.1 | In-house | 2-278 (278) | alignment | ||
Range on Protein: 130-405
Range on HMM: 2-278/278.0
VKWKAEDVAVAYIGKLDASQTRPEYIDVCVATKaNIENCTVWKKNLAKNQTDVYPILDATLVKDPAKP----DSYVNMSSVIVPHCSYPILMGQIPKRGL
...| |...... . . .. |. ... .. . ... ...| ||.. ....| ..|| . ..|.| | | ..... ... | | .
isvkdllkallelllnlktllllefeellsfkl.dtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpet
EEEFWRAAYNEQVVMMYVLVGSEDEK----YDFFPkttGSFLYYGEMFVNVRKVEKmDEERSRYTIEVLPNGFSNSVMMNVYVHTGWEPFGVPIRYANTT
.| ||| ....| . .|.. .. . . ..| |..|.||...|...|.|. .. ..|.|| ..| ..| . ..| ..|| .||| .
vedFwrmvwelgvttivmLtelvelgrvkcaqYwp...ggsltygdftvtllkeeh.lddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslslll
RSVVDVMNFVKssNGSEKLLVVSKNGCGRAGFFITLGAAFCCLNDNSEPRIGEIVKAIRSQRPNAVESIKQYASLYLCLLYYIK
. . .|..... . ....|| ...|.||.| ||.| ....|... .. . |.|| .|.|||.||.. || || .||.|.|
dflkavreale..dsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyealleylk
|
|||||||||
0046845 | (Phosphotyrosine protein) phosphatases II | 167-411 | 8.4e-44 | 145.4 | In-house | 21-281 (284) | alignment | ||
Range on Protein: 167-411
Range on HMM: 21-281/284.0
NCTVWKKNLAKNQTDVYPILDATLVKDPAKP-----DSYVNMSSVIVP-----HCSYPILMGQIPKRGLEEEFWRAAYNEQVVMMYVLVGSEDE----KY
.......|| ||. ....| . || . ..|.| | | .. ... ... | |. . |.||| ....| . .| . .. .
svallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqnvrvIVmltelvengrekca
DFFPKTtGSFLYYGEMFVNVRKVEKmDEERSRYTIEVLPNG-FSNSVMMNVYVHTGWEPFGVPIRYANTTRSVVDVMNFVKSSNGSEKLLVVSKNGCGRA
..| . |..|.||...|.....|. .. ..|.|. ..| ..|...... .|.| .||| .. . . .| .. ....|... .| ...|.||.
qYwple.gevltygdftvtllseev.kddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrellenlpgggpivVHCsaGvgRt
GFFITLGAAFCCLNDNS---EPRIGEIVKAIRSQRPNAVESIKQYASLYLCLLYYIKKKITVP
| ||.| ....|. .. .. . |.|| .|.|||..|.. || .| .||.|.|.|.|..
GtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleylklkltll
|
|||||||||
DSPc_SM00195 | 167-405 | 8.9e-42 | 138.6 | In-house | 19-263 (263) | alignment | |||
Range on Protein: 167-405
Range on HMM: 19-263/263.0
NCTVWKKNLAKNQTDVYPILDATLVKDPA----KPDSYVNMSSVIVPHCSYPILMGQIPKRGLEEEFWRAAYNEQVVMMYVLVGSEDE----KYDFFPKT
... .||| .||. ... | | || . ....|.| . . ..... . . | |. |.||| ..|.| . ..|. |.. ....|..
teaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengkekcdrywpee
TGSFLYYGEMFVNVRKVEKMDEERSRYTIEVLPNGFSNSVMMNVYVHTGWEPFGVPiryaNTTRSVVDVMNFVKSSNG--SEKLLVVSKNGCGRAGFFIT
|. .|.. |....|||...| ..|.|. .| ... ...| ...|. ||| ..|.||......||.|. |. ..|....|.||.| |.|
sggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvp....dstksvlellravkkskstssgpivVhCsaGvgRtgtfvt
LGAAFCCLNDNSEPRIGEIVKAIRSQRPNAVESIKQYASLYLCLLYYIK
. . |...... | ||||..|.|||..|.. .||. .| ..|.|||
idiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyik
|
|||||||||
PTPc_SM00194 | 167-405 | 8.9e-42 | 138.6 | In-house | 19-263 (263) | alignment | |||
Range on Protein: 167-405
Range on HMM: 19-263/263.0
NCTVWKKNLAKNQTDVYPILDATLVKDPA----KPDSYVNMSSVIVPHCSYPILMGQIPKRGLEEEFWRAAYNEQVVMMYVLVGSEDE----KYDFFPKT
... .||| .||. ... | | || . ....|.| . . ..... . . | |. |.||| ..|.| . ..|. |.. ....|..
teaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengkekcdrywpee
TGSFLYYGEMFVNVRKVEKMDEERSRYTIEVLPNGFSNSVMMNVYVHTGWEPFGVPiryaNTTRSVVDVMNFVKSSNG--SEKLLVVSKNGCGRAGFFIT
|. .|.. |....|||...| ..|.|. .| ... ...| ...|. ||| ..|.||......||.|. |. ..|....|.||.| |.|
sggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvp....dstksvlellravkkskstssgpivVhCsaGvgRtgtfvt
LGAAFCCLNDNSEPRIGEIVKAIRSQRPNAVESIKQYASLYLCLLYYIK
. . |...... | ||||..|.|||..|.. .||. .| ..|.|||
idiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyik
|
|||||||||
0045450 | (Phosphotyrosine protein) phosphatases II | 165-407 | 7.4e-41 | 136.2 | In-house | 46-307 (307) | alignment | ||
Range on Protein: 165-407
Range on HMM: 46-307/307.0
IENCTVWKKNLAKNQTDVYPILDATLVKDPA-----KPDSYVNMSSV--------IVPHCSYPILMGQIPKRGLEEEFWRAAYNEQVVMMYVLVGSEDEK
... ...| ||. ....| | || ....|.|.| | ..... ... | |. . |.||| ....| . | .... .
eysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydlkrkfIatqgPlpetvedFwrmlweqgvtvivmltelvelg
Y----DFFPKTtGSFLYYGEMFVNVRKVEKmDEERSRYTIEVLPN-GFSNSVMMNVYVHTGWEPFGVPIRYANTTRSVVDVMNFVKSSNGSEKLLVVSKN
..| . |..|.||...|.....|. ... ..|.|| .. | ..| . ... .||| .||| . . . . |............ || ..
rekcaqywPde.geeltygnftvtllseeh.ldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfeelldfieevrkaleelpkggpvlVHCsa
GCGRAGFFITLGAAFCCLNDNSE---PRIGEIVKAIRSQRPNAVESIKQYASLYLCLLYYIKKK
|.||.| ||.. . ..|... . . . |.|| .|.|||.||.. || || .||....||
GvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeallelllkk
|
|||||||||
0040439 | (Phosphotyrosine protein) phosphatases II | 167-406 | 1.8e-40 | 134.5 | In-house | 4-248 (249) | alignment | ||
Range on Protein: 167-406
Range on HMM: 4-248/249.0
NCTVWKKNLAKNQTDVYPILDATLVKDPA----KPDSYVNMSSVIVPHCSYPILMGQIPKRGLEEEFWRAAYNEQVVMMYVLVGSEDE----KYDFFPKt
... ...|. ||. ....| . || ...|.|.| . ..... ... | | . | ||| ..... . | . . ..|
svallpenkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywpl.
tGSFLYYGEMFVNVRKVEKmDEERSRYTIEVLPNGFSNSVMMNVYVHTGWEPFGVPIRYANTTRSVVDVMNFVKSSNGSEKLLVVSKNGCGRAGFFITLG
|..|.||...|....||. .. ..|.|. ......|.. ... .|.| .||| . . . . |...... . ....|| ...|.||.|.||..
.ggsleygdftvtllsvev.kddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaay
AAFCCLNDNSEPRIGEIVKAIRSQRPNAVESIKQYASLYLCLLYYIKK
....|. . . . |.|| .|||||.||.. || || .||....|
lmleqlekelgvdleeavkllrsqRpgavqnpeqyrflyeallelllk
|
|||||||||
0051299 | (Phosphotyrosine protein) phosphatases II | 144-405 | 2.9e-40 | 133.9 | In-house | 19-287 (288) | alignment | ||
Range on Protein: 144-405
Range on HMM: 19-287/288.0
KLDASQTRPEYIDVCVATKANIENCTVWKKNLAKNQTDVYPILDATLVK----DPAKPDSYVNMSSVIVPHCSYPILMGQIPKRGLEEEFWRAAYNEQVV
. . .. . |. ... . . .......|| ||. .. .| . || |. ...|.| | . ..... .. | |. . |.||| ....|
angltglleefeellsllpdltlsaallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyidgynlkrkfIatqgPlpntvedFWrmvweqnvr
MMYVLVGSEDE----KYDFFPKttGSFLYYGEMFVNVRKVEKmDEERSRYTIEVLPN----GFSNSVMMNVYVHTGWEPFGVPIRYANTTRSVVDVMNFV
. .| . .. . ..| |..|.||...|. ...|. ... .|.|| .. | ..| . ... .|.| .||| . . .|...
vIvmltklvelgrekcaqYwpl..ggsltygditvtllseev.lddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdspellldflrlvrkal
KssNGSEKLLVVSKNGCGRAGFFITLGAAFCCLNDNSEPRIGEIVKAIRSQRPNAVESIKQYASLYLCLLYYIK
. .|. .| ...|.||.| ||.| ....|. . .. . |.|| .|.|||..|.. || .| .||.|.|
a..sgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyealleylk
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 174-401 | 2.5e-39 | 130.5 | Pfam-A | 1-234 (235) | alignment | ||
Range on Protein: 174-401
Range on HMM: 1-234/235.0
NLAKNQTDVYPILDATLVKD--PAKPDSYVNMSSVIVPHCSYPILMGQIPKRGLEEEFWRAAYNEQVVMMYVLVGSEDE----KYDFFPKTTGSFLYYGE
|. ||. ... | | || .| |.| . | . . ... | | |.||| ..|.| . ..|. |.. ...|.... .|.||.
nkkknRykdilpydktrvklkgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesltygd
MFVNVRkvEKMDEERSRYTIE--VLPNGFSNS--VMMNVYVHTGWEPFGVPiryaNTTRSVVDVMNFVKSSN--GSEKLLVVSKNGCGRAGFFITLGAAF
..|... || |. ..||.. | . ..| ..... .|.|. ||| ....|..|... |..|. |....|....|.||.| |..| ...
ikvelk..ekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvp....espkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldill
CCLNDNSEPRIGEIVKAIRSQRPNAVESIKQYASLYLCLL
..|....|. . .||| .|.|||..|.|..||. || ..|
eqleaeeevdvlqivkelRkqRpgmvqsleqYiflykail
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 174-401 | 2.5e-39 | 130.5 | In-house | 1-234 (235) | alignment | ||
Range on Protein: 174-401
Range on HMM: 1-234/235.0
NLAKNQTDVYPILDATLVKD--PAKPDSYVNMSSVIVPHCSYPILMGQIPKRGLEEEFWRAAYNEQVVMMYVLVGSEDE----KYDFFPKTTGSFLYYGE
|. ||. ... | | || .| |.| . | . . ... | | |.||| ..|.| . ..|. |.. ...|.... .|.||.
nkkknRykdilpydktrvklkgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesltygd
MFVNVRkvEKMDEERSRYTIE--VLPNGFSNS--VMMNVYVHTGWEPFGVPiryaNTTRSVVDVMNFVKSSN--GSEKLLVVSKNGCGRAGFFITLGAAF
..|... || |. ..||.. | . ..| ..... .|.|. ||| ....|..|... |..|. |....|....|.||.| |..| ...
ikvelk..ekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvp....espkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldill
CCLNDNSEPRIGEIVKAIRSQRPNAVESIKQYASLYLCLL
..|....|. . .||| .|.|||..|.|..||. || ..|
eqleaeeevdvlqivkelRkqRpgmvqsleqYiflykail
|
|||||||||
0042113 | (Phosphotyrosine protein) phosphatases II | 167-405 | 3.8e-38 | 126.7 | In-house | 2-244 (245) | alignment | ||
Range on Protein: 167-405
Range on HMM: 2-244/245.0
NCTVWKKNLAKNQTDVYPILDATLVKDPAKP----DSYVNMSSVIVPHCSYPILMGQIPKRGLEEEFWRAAYNEQVVMMYVLVGSEDE----KYDFFPKt
... ...| ||. ....| |.|| . . ..|.|.| | ..... ....| | .. | ||| ..... . | |. . ..|
svallpenkdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywpl.
tGSFLYYGEMFVNVRKVEKmDEERSRYTIEVLPNGFSNSVMMNVYVHTGWEPFGVPiryaNTTRSVVDVMNFVKS---SNGSEKLLVVSKNGCGRAGFFI
|..|.||...|.....|. ... ..|.|| ..| . | . ..| ...|. .||| .......|...||.. .......|| .. |.||.| ||
.gesltygdftvtllseeh.lddytvrtlevtnlgddesrevihyhylpwpdhgvp....dllellldflefvrkalaedsngpvlVHCsaGvgRtGtfi
TLGAAFCCLNDNSEPRIGEIVKAIRSQRPNAVESIKQYASLYLCLLYYIK
.. ....|. . . . |.|| .|||||.||.. || || .||...|
aaylmleqlekelgvsleeavkelrsqRpgavqtpsqyrflyeallellk
|
|||||||||
subfamily_Cele-PTP-5_pd | Subfamily Cele-PTP-5 | 218-408 | 3.9e-35 | 115.1 | In-house | 123-313 (346) | alignment | ||
Range on Protein: 218-408
Range on HMM: 123-313/346.0
GQIPKRGLEEEFWRAAYNEQVVMMYVLVGSEDEKY---DFFPKTTGSFLYYGEMFVNVRKVEKMdEERSRYTIEVLPNGFSNSVMMNVYVHTGWEPFGVP
|. . . |.|| |.||. ..|..| . | .| | . | | ||.| |. . . |||||||.| |.||. .|. |. | . |
pqmenesfvedfwymiyqeqihlvylmvpddklkntttslfndenggyqytgkmfinnrradvs.gdpkeytievlpegnsdsvicqvhhhapwkhlqqp
IRyantTRSVVDVMNFVKSSN--GSEKLLVVSKNGCGRAGFFITLGAAFCCLNDNSEPRIGEIVKAIRSQRPNAVESIKQYASLYLCLLYYIKKKI
. | .. .. .| . . . ||| ||||| || | ||. || | ||.|.|. ||| .|||. ||||.| .. || .|
pk....tlpiikmihqflsekqvqnagvcvvslfgcgracsfigalyainqlnngiepniceimknikqqrpggvesfaqyasiyaivfdyiarkr
|
|||||||||
0037934 | (Phosphotyrosine protein) phosphatases II | 168-404 | 1.7e-24 | 82.2 | In-house | 4-242 (243) | alignment | ||
Range on Protein: 168-404
Range on HMM: 4-242/243.0
CTVWKKNLAKNQTDVYPILDATLVKDpaKPDSYVNMSSVIVPHcsYpILMGQIPKRGLEEE----FWRAAYNEQV---VMMYVLVGSEDEKYDFFPKttG
. .. || ||. .. .| . || ....|.| . . |. . . .| | . |. ||| ..... ||. || . ||.. . |
iallpenlsknrysdilpydhsrvkl..egsdyinanliyvtp..r.liatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywp..g
SFlYYGEMFVNVRKVEKMDEERSRYTIEVLPNGFSNSVMMNVYVHTGWEPFGVPIRYANTTRSVVDVMNFVKS------SNGSEKLLVVSKNGCGRAGFF
.. .||...|.. ..| .|. |. . .. . . | ...| .||| .. . . .| .|... ......|| . |.||.| .
ev.tygdftvtllseehlddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtl
ITLGAAFCCLndnsEPRIGEIVKAIRSQRPN-AVESIKQYASLYLCLLYYI
|.. .| . . |.|| .|.|||. ||.. || || .||...
iaaylmllll....gvdleeavkllreqRpgkavqtpsqyrflyeallell
|
|||||||||
0045098 | (Phosphotyrosine protein) phosphatases II | 168-406 | 6.8e-24 | 80.2 | In-house | 27-274 (278) | alignment | ||
Range on Protein: 168-406
Range on HMM: 27-274/278.0
CTVWKKNLAKNQTDVYPILDATLVKdpakpDsYVNMSSVIVPhcSYPILMGQIPKRGLEEEFWRAAYNEQVVMMYVLVGSEDE---K-YDFFPKttGSFL
. .. .||.|| .. .| . || | |.| | . .. . .. | |. . ||| ..... | . .. | . ..| |..|
palylgnldknRykdilpydhsrVk.....d.YINAsyidgy..pkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaqywpe..ggsl
YYGEMFVNVRKVEKMdEERSRYTIEVLPN----GFSNSVMMNVYVHTGWEPFGVPIRY-ANTTRSVVDVMNFVKS------------SNGSEKLLVVSKN
.||...|.. ..| . .. |..| | .... ..|. .||| . .... .. . . ..... || .
tygdftvtllseevl.ddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvlVHCsa
GCGRAGFFITLGAAFCCLndNSEPRIGEIVKAIRSQRPN-AVESIKQYASLYLCLLYYIKK
|.||.| .. . ..| .. . |.|| .|||||. ||.. || || .||.....
GvgRtGtlvaaylmlell..eggvdlleavkelrsqRpglavqnleqyrflyefllelllr
|
|||||||||
subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 199-410 | 4.2e-21 | 70.4 | In-house | 77-295 (325) | alignment | ||
Range on Protein: 199-410
Range on HMM: 77-295/325.0
SYVNMSSVIVPHCSYPILMGQIPKRGLEEEFWRAA--YNEQVVMMY-VLVGSEDEKYDFFPKTTGSFLYYGEMFVNVRKVEKMDEERSR-YTIEVLPNGF
|.| | . | | |. ...|| . .. ||.. .| . .|. ..|| | .| . |..| .|.. . | . . .|
dyinasylrddkkkdvflaaqaPltatindlWrlvldWrcsvvvvlneldlgkdrcavywpkemgksktfGglevklrtieeisdyvhrvldvkqvkkGe
SNSVmmNVYVHTGWEPFGVPIR---YANTTRSVVDVMNFVKS-SNGSEKLLVVSKNGCGRAGFFITLGAAFCCLNDNSEPRIGEIVKAIRSQRPNAVESI
. || . . . .|. .||. | .. .. | | . |.. ...| .|| .| ||.| ||.| .| . ..|. | . || .| .||. ||..
trsv..kqfqlqswddmGvqkrpatlisilqlvkavservtantkastpilvhcsaGvGrtGvfislysalakvieesrvdifgfvkklrkdrpsmvetv
KQYASLYLCLLYYI-KKKITV
|| .| .| .. . |
dqyiliyealveaymsgntdv
|
|||||||||
subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 194-405 | 2.2e-20 | 67.9 | In-house | 71-280 (288) | alignment | ||
Range on Protein: 194-405
Range on HMM: 71-280/288.0
PAKPDSYVNMSSVIVPHCSYPILMGQIPKRGLEEEFWRAAYNEQ---VVMMYVLVGSEDEKYDFFPKTTGSFLYYGEMFVNVRKVEKMDEERSRYTIEVl
. |.| | . . . . . | | ..||. |... .||. || ...| . . ... ||.. | ......... | . .
eeagaDYinasyidgekkkkkyiatqgPladtvndfWelvyenktstivmltelveggktkCeeYWPdadkpknyGsvtvtlveskeledfvlrkllle.
pnGFSNSVMMNVYVHTGWEPFGVPiryaNTTRSVVDVMNFVKSSNGSE--KLLVVSKNGCGRAGFFITLGAAFCCLNDNSEPRIGEIVKAIRSQRPNAVE
. . .. | ...| ||| . .. ...... || .| .. ...|. .| ||.| ||.| |. .. . . ..|. .| ||.. |.
..kkkteleitqyqylaWpdhgvP....eskapllellrqvkvanqadtgpiivhCsaGvGrtgtFialdalidaveeedyiDvagtvaklRkqRallvq
SIKQYASLYLCLLYYIK
||| .| .|| |.
tlkqYefiyevllslie
|
|||||||||
subfamily_PTPN23_pd | Subfamily PTPN23 | 160-406 | 1.1e-19 | 65.4 | In-house | 29-282 (288) | alignment | ||
Range on Protein: 160-406
Range on HMM: 29-282/288.0
ATKANIENCTVWKKNLAKNQ-TDVYPIlDATLVKDPAKPDSYVNMSSV--IVPHCSyPILMGQIPKRGLEEEFWRAAYNEQVVMMYVLVGSEDEKY----
. .|. ... |.. ||. .|. | | . || . | |.| | | ..| | .... | |... .||. |.... .. .|. |. .
dkearkrsiaiaklyseknrsrdilPy.DhnRvklrgskDDYinAsfvkdlspgcP.dfiatqaPlqstlnDFWlmvyeqkssviVmllskeelgkpkvd
DFFPKTTGSFLYYGEMFVNVRKVEKMDeERSRYTIEVLPNGFSNSVMMNVYVHTGWEPFGVPIRYANTTRSVVDVMNFV-KSSNGSE-KLLVVSKNGCGR
..|. .| .|.. | ...|.... . ....... .. .. .. | | .||| . . . | . . . |. |.| | ||
rYwPedkgetvkfgdlsvtlksvrete.thvervlkletldadavksvshlqltsWpelGvPasPetllqfldevesayeavqrksktPlvvhCsaGvgR
AGFFITLG-AAFCCLNDNSEPRIGEIVKAIRSQRPNAVESIKQYASLYLCLLYYIKK
.| | . |. ..| . | ..|. .| || . |. .|. .| | ....
tgvfalvyaavrelekgnglldiiqvvsrlreqRrfmvqekeqlkfsyeavleaarr
|
|||||||||
subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 153-419 | 2.8e-19 | 64.4 | In-house | 27-300 (305) | alignment | ||
Range on Protein: 153-419
Range on HMM: 27-300/305.0
EYIDVCVATK-ANIENCTVWKKNLAKNQTDVYPILDATLVKDPAKP-DSYVNMSSVIVPHCSYPILMGQIPKRGLEEEFWRAAYNEQVVMMYVLV----G
.| .. . .... .. |.. . ... ... | ... .. |.| | | . . .. | | . ..||| ..|.|. . |. |
qykslyeeeesidvgkkeankaknrlkeitlldddriiltekeslddsdyinasyvdgykrkkkyivaqgPlkntvadfWrliveekvstivmltklveg
SEDEKYDFFPKTTGSFLYYGEMFVNVRKVEKMDEERSRYTIEVLPNGFSNSVMMNVYVHTGWEPFGVPiRYANTTRSVVDVMNFVKSSNGSEKLLVVSKN
.| . ..|.... .||. |... ... . | .. ..| . | | | ||| ..| . |... .. .... |||. .
gkdkCrqYWpesktekkefgefsvelksektasdyieRklkisiededkesrtvlqyqltdWPdhGvp.qfatsllslikrvqkdqkkdkgvpllVhCsa
GCGRAGFFITLGAAFCCLNDNSEPRIGEIVKAIRSQRPNAVESIKQYASLYLCLLYYIKKKI--TVPEGLQQKVE
| ||.| ||.. |. |. . . |..|..||.|...|.. .|| .|. | .|. . . |. .|.
gvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkmvqtldqYvflhdaldelitcgdtsiigsnlrarvn
|
|||||||||
subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 197-405 | 3.2e-19 | 64.1 | In-house | 36-243 (250) | alignment | ||
Range on Protein: 197-405
Range on HMM: 36-243/250.0
PDSYVNMSSVIVPHCSYPILMGQIPKRGLEEEFWRAAYNE---QVVMMYVLVGSEDEKYDFFPKTTGSflYYGEMFVNVRKVEKMDEERSRyTIEVLPNG
|.| | . . . . .. | | |.||| ..| .||. |. || . ...| . ||.. |.. . |.. . .| .. . .
esdyinasflhgyderkafiatqgPlqatiedfWrmvleeksgtivmLtnLkesektyhqywPvekae..kyGdvtvsllskeefadytkr.klklskak
FSNSVMMNVYVHTGWEPFGVPiryaNTTRSVVDVMNFVKSSNGS---EKLLVVSKNGCGRAGFFITLGAAFCCLNDNSEPRIGEIVKAIRSQRPNAVESI
...... . .. | ||| .....|..... |..|. ..| .| ||.| ||.. | . |. . . ...|..| .||.||||
kaderivrqlhfvvWPdkgvP....evatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidavlerlkkekvvdvfkvikvlrkdrphavesl
KQYASLYLCLLYYIK
.|| ..| .| ...
eqyvfvyeiilkald
|
|||||||||
PTPc_DSPc_SM00012 | 300-402 | 4.9e-19 | 63.9 | In-house | 2-105 (105) | alignment | |||
Range on Protein: 300-402
Range on HMM: 2-105/105.0
MNVYVHTGWEPFGVPIRYANTTRSVVDVMNFVKSSNGSEKLLVVSKNGCGRAGFFITLGAAFCCLNDN-SEPRIGEIVKAIRSQRPNAVESIKQYASLYL
...| .||| .||| . . .. . .|... . |. |. ..|....|.||.| |..| . . |... .|. | .|||..|.|||..|.. || ||
vkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylflyr
CLLY
.||.
alle
|
|||||||||
subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 196-405 | 3.2e-18 | 61.0 | In-house | 82-291 (298) | alignment | ||
Range on Protein: 196-405
Range on HMM: 82-291/298.0
KPDSYVNMSSVIVPHCSYPILMGQIPKRGLEEEFWRAAYNEQ---VVMMYVLVGSEDEKY-DFFPKTTGSflYYGEMFVNVRKVEKMDEERSRyTIEVLP
. |.| | . . . . .. | | |.||| .|. .||. |. .. || ..|.. |||. |.... |.. . .| ...|
eesdYiNAsflhaykgrnafiatqaPltetvedFWrmvteedigtiVmltnleeldktkyhkywPdegke..tygeitvsllskeefadlivr.klkvsk
NGFSNSVMMNVYVHTGWEPFGVPiryaNTTRSVVDVMNFV---KSSNGSEKLLVVSKNGCGRAGFFITLGAAFCCLNDNSEPRIGEIVKAIRSQRPNAVE
. ... .. .| | ||| ....||.|... | .. .| . ..| .| ||.| || . . . .. .. . ..||..| .||.||.
kkeekerevrqlhftsWpdkgvp....enatsvldllrkvrasqqqagnkpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavq
SIKQYASLYLCLLYYIK
. .||. .| | ...
teeqYvfiyeavleald
|
|||||||||
subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 221-407 | 6.2e-18 | 59.7 | In-house | 72-267 (270) | alignment | ||
Range on Protein: 221-407
Range on HMM: 72-267/270.0
PKRGLEEEFWRAAYNEQV---VMMYVLVGSEDEKY-DFFPKTTGSFLYYGEMFVNVRKVEKMDEERSRYT-IEVLPNGFSNSVMmnVYVHTGWEPFGVPI
|. ..||| ..|.| ||. |. .| ..|. ... . . .....|..... || .. | ... .| .. .. . .. | |||
PlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkekvkledgkikvlalseekeegyiltrlrleekgeerrlv..HfwyntWpdhgvpr
RYA--NTTRSVVDVMNFVKSSNGSE----KLLVVSKNGCGRAGFFITLGAAFCCLNDNSEPRIGEIVKAIRSQRPNAVESIKQYASLYLCLLYYIKKK
. .|.... ... |. |. . ||| .| ||.| .|.| |...|. ... . .|....| .|.. |. .||. || .. |....
eedsslstdqllkmlravrrsekeldkaePllvHcsaGvgRtGtlialDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyeflykavveyaerr
|
|||||||||
subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 193-433 | 1.3e-17 | 58.1 | In-house | 66-307 (515) | alignment | ||
Range on Protein: 193-433
Range on HMM: 66-307/515.0
DPAKPDSYVNMSSVIVPHCSYPILMGQIPKRGLEEEFWRAAYNEQVVMMYVL-VGSEDEKY---DFFPKTTGSFLYYGEMFVNVRKVEKMDEERSRyTIE
. . |.| | . .. . | |.. ..||| ..|.| . .. .|..| ..|. | . .|.. |.. .| . | ...
ndnPhsdyfnasyipsfdndkayiasqgPnkasvddfWrlvlqenvttiamvtklkegdkikcgkyWPdkpgdsvkfGsikvelvsleactggikr.klt
VLPNGFSNSVmmNVYVHTGWEPFGVPIRyantTRSVVDVMNFVKSSNGS--EKLLVVSKNGCGRAGFFITLGAAFCCLNDNSEPRIGEIVKAIRSQRPNA
|| . |. | . |.| ||| . |.|.. .. ||...| |.. | ||.| .|.. .. . ..|. || .||
vlkgddsrtv..tqfhfteWPdkGvpkh....tssllklikevkadhgqythpliihcsaGvGrtGvvisidsvvahakttrmvdvfnfvtnirqkrpyl
VESIKQYASLYLCLLYYIKKKIT-VPE-GLQQKVEDLKRGLEGITREDL
| ||| .| .| ... . | .| . ....||. .| | .
vqtqeqyafiygavledllwrntlipvihftdhlqdlhssgdgrgrskm
|
|||||||||
subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 191-434 | 1.4e-17 | 58.5 | In-house | 65-309 (315) | alignment | ||
Range on Protein: 191-434
Range on HMM: 65-309/315.0
VKDPAKPDSYVNMSSVIVPHCSYPILMGQIPKRGLEEEFWRAAYNEQVVMMYVLV-GSEDEK---YDFFPKTTGSFLYYGEMFVNVRKVEKMDEERSRYT
| | . |.| | . .. . | |.. ..||| ..|.| . .. .|..| ..|. . .|.. |.. ..| . |
viddsPdsdyinasyiksvdddkayiasqgPlkasvddfwrmvlqekvttivmvtkkqegdkikcrqywPdrkadsvefGsikvellsleadtdgvarkl
ieVLPNGfSNSVMMNVYVHTGWEPFGVPIRYAnttrSVVDVMNFVKSSNGSEK--LLVVSKNGCGRAGFFITLGAAFCCLNDNSEPRIGEIVKAIRSQRP
|. .. .| . . |.| ||. . . |.. .. ||..||... ||| | ||.| .|.. ..... . ..|| .|..||
..vtrks.eesrtvtqfqftewPdkGvdkqts....sllklikevkadngkkefsllvhcsaGvGrtGvvisidevvaqikrtrsvdvfnfvknlrakrp
NAVESIKQYASLYLCLLYYIKKKITV--PEGLQQKVEDLKRGLEGITREDLT
| . ..|| .| .| ... . |. . ....||. .| | .|
ylvqteeeyafiydavledllwrntlilvihftdhlqdlhtsvdgsgrskmt
|
|||||||||
subfamily_PTPRB_pd | Subfamily PTPRB | 173-407 | 2.5e-17 | 57.9 | In-house | 50-288 (293) | alignment | ||
Range on Protein: 173-407
Range on HMM: 50-288/293.0
KNLAKNQTDVYPILDATLVKD----PAKPDSYVNMSSVIVPHCSYPILMGQIPKRGLEEEFWRAAYNEQ---VVMMYVLVGSEDEKYD-FFPKTTGSFlY
.| |||. |.. || . . |.| . . .. . | | . ..||| .... .||. || .| . ..|... . .
vnraknrytnilpydhsrvkLaalkdesgsDYinanyipgynsprefiatqGPlpetvddfWrmvwekkssiivmltqlvekgkvkCeeYWPadeepv.l
YGEMFVNVRKVEKMDEERSRyTIEVLPngFSNSVMMNVYVHTGWEPFGVPiryaNTTRSVVDVMNFV----KSSNGSEKLLVVSKNGCGRAGFFITLGAA
||.. |.. . |.... | .... ... .. | .| | .||| ..|....| .. | .... .. ..| | ||.| ||.|
yGdikvtlvaeeeledwvir.elkiek..ekeerkvrqyhftsWpdhgvP....ektktlldfvrtvreaiektaskrPivvhCsaGvGRtGtfialdrl
FCCLNDNSEPRIGEIVKAIRSQRPNAVESIKQYASLYLCLLYYIKKK
. .... | || ..|..| . | . ||| .. |.| ...||
lqaieeedyvdifgivaelReeRnllvqtekqYifihqcvldllrkk
|
|||||||||
subfamily_PTPRA_pd | Subfamily PTPRA | 214-404 | 1.1e-16 | 55.6 | In-house | 102-296 (330) | alignment | ||
Range on Protein: 214-404
Range on HMM: 102-296/330.0
PILMGQIPKRGLEEEFWRAAYNE---QVVMMYVLVGSEDEKYDFFPKTTGSFlYYGEMFVNVRKVEKMDEERSR-YTIEVLPNGF--SNSVMMNVYVHTG
. | ||. |.||| .. .||. | ..|| . . |.. ||.. |.|.... . . | . .. ||.. .| ... . |.
kfiaaqGPkeetvedfwrmiweqksativmltelkerkeekcaqywPdeGlv.tyGnirvevedetvlvdytvrkflvqqlpdatrekksrlvrqfhfts
WEPFGVPIryanTTRSVVDVMNFVKSSNGS--EKLLVVSKNGCGRAGFFITLGAAFCCLNDNSEPRIGEIVKAIRSQRPNAVESIKQYASLYLCLLYY-I
| .|||. ... ...... ||. | . . | | ||.| ||.| | . .. . . |.|| .| |||. | . .|| .| || | .
wPdvGvPf....epiGmlkllkkvkklnqqsagpivvhcsaGvGrtGtfivldavlervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvlleyyl
|
|||||||||
subfamily_PTPRD_pd | Subfamily PTPRD | 223-422 | 1.1e-16 | 55.6 | In-house | 101-301 (564) | alignment | ||
Range on Protein: 223-422
Range on HMM: 101-301/564.0
RGLEEEFWRAAYNEQ---VVMMYVLVGSEDEKYD-FFPKTtGsFLYYGEMFVNVRKVEKMDEERSRyTIEVLPNGFSNSVMMNVYVHTGWEPFGVPirya
|.||| .... .||. |. .. .|.. ..|.. | |||. |.. . |.. . | |... . |.| . . . .| | |||
aetiedFWRmvweqnsstiVmltkleEkgkvkchkYWPek.g.tetygeltVtleeeeeladyeir.tfklkkkkssesreVrqFhFtsWPdhgvp....
NTTRSVVDVMNFVKSSNGSEK--LLVVSKNGCGRAGFFITLGAAFCCLNDNSEPRIGEIVKAIRSQRPNAVESIKQYASLYLCLLYYIKKKITV--PEGL
....|..|... |...| ... ..| .| || | ||.. | .... | ..|||.|.||. |.. .||. .. .| .... | | |
esatslLdlirkvralnepdagPivVhCSaGVGRTGtfividamlerikeektvDiyqyvkalrkqRnamVqteeQYiFiheailealacgntevesenl
QQKVEDLK
.|... |.
kqhlqkLa
|
|||||||||
subfamily_PTPRK_pd | Subfamily PTPRK | 199-401 | 1.4e-16 | 55.2 | In-house | 72-274 (314) | alignment | ||
Range on Protein: 199-401
Range on HMM: 72-274/314.0
SYVNMSSVIVPHCSYPILMGQIPKRGLEEEFWRAAYNEQ---VVMMYVLVGSE-DEKYDFFPKTTGSflyYGEMFVNVRKVEKMDEERSR-YTIEVLPNG
|.| . . . . .. | |.. ..||| |.|. .||. || . . ..|. | ||.. |.. ..| | .| ...| | |
dyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasivmltelvevgrvkClkyWPedtev...ygdikvelvetellaelvvrifrveklarg
FSNSVMMNVYVHTGWEPFGVPIRYANTTRSVVDVMNFVKSsnGSEKLLVVSKNGCGRAGFFITLGAAFCCLNDNSEPRIGEIVKAIRSQRPNAVESIKQY
.. ... . ..|| ..|| . | | . . . ...| .|.||.| ||.. .. .. . ..||..||...| || .||
qeeirevrqfqflgWpdhdvPvsatgllklvrrvkksqee..eaGrivvhCsaGaGrtGtfiaidivldmieregvvdvfnavktlrsrkvnmveteeqy
ASLYLCLL
.| .|
kfiydvil
|
|||||||||
subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 154-408 | 1.6e-16 | 55.3 | In-house | 29-287 (319) | alignment | ||
Range on Protein: 154-408
Range on HMM: 29-287/319.0
YIDVCVATKANIENCTVwKKNLAKNQTD-VYPiLDATLVKDPA---KPD-SYVNMSSVIVPHCSYPILMGQIPKRGLEEEFWRAAYNEQVVMMYVLVGsE
. .. |.. ...... ..| ||. . . | | |. .. ... |.| | . . . | |. |.||| ..|.. .. .| .
fkllkeavndtfdsask.eenkkknryqnila.ydrtrvvlseldgvegsdyinasfidgyqerekfiatqaPlentiedfWrmvWeeessivvmltk.l
DEKYDF-FPKT--TGSFLYYGEMFVNVRKVEKMDE-ERSRYTIEVLPNGFSNsVMMNVYVHTGWEPFGVPiryaNTTRSVVDVMNFVKSSN---GSEKLL
|| . . |. . | ||.. |.. . |.... . .. ... . . .. . .| | .|| ....|..|... .. | | .
veklkvklkkywpeenfeeyGrlivtleeeeeledyiirklklnkkssevet.RevkhfqyteWpdhdvP....ekatslldllkrirksrektqsgPiv
VVSKNGCGRAGFFITLGAAFCCLNDNSEPRIGEIVKAIRSQRPNAVESIKQYASLYLCLLYYIKKKI
| .| || | ||.| |.. .. .. . ..|. .| ||. |. .|| .| || ...
vhCsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyealleaveagd
|
|||||||||
subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 153-404 | 1.9e-16 | 55.1 | In-house | 28-284 (297) | alignment | ||
Range on Protein: 153-404
Range on HMM: 28-284/297.0
EYIDVCVATKANIENCTVWKKN--LAKNQ-TDVYPIlDAT---LVKDPAKPDS-YVNMSSVivPHCSYPILMGQIPKRGLEEEFWRAAYNEQVVMMYVLV
..... .||| . || .|. . |.. ... |. | | .||| ||| | | . . .. | |.. ..||. ..||| .. .|
fseeflclpeaniqpqtvaekkvnfeksRYkniLPy.dssRvkLaivnddpdsDyvnasfv..kgnkhrlittqmPmkatvadfWamvldeqvstivmln
G--SEDEKY-DFFPKTTGSFlyYGEMFVNVRKVEKMDEERSRyTIEVLPNGFSNSVMMNVYVHTGWEPFGVPIRyaNTTRSVVDVMNFVKSS---NGSEK
.|.| ...... . .|.. | . |.. | ..|| . . ... | .. | |. . ....|...... |. . | .
ddnerdkkcaryWsdkgvtt..fGdvsvvllsvsereGfikr.elevtkgkakarrvvkqyqfveWPdkaverk..dsassllklisevrkdfsqnaegP
LLVVSKNGCGRAGFFITLGAAFCCLNDNSEPRIGEIVKAIRSQRPNAVESIKQYASLYLCLLYYI
||| .| ||.| ..|. . ... | | ..|| .| .||. | .||. .| .| ..
llvhclaGvGrtgvlltidsvvaeakrekevdifglvkklrqerpylvqtkeqykfvyvavleal
|
|||||||||
subfamily_PTPN12_pd | Subfamily PTPN12 | 190-410 | 7.7e-16 | 52.8 | In-house | 59-283 (290) | alignment | ||
Range on Protein: 190-410
Range on HMM: 59-283/290.0
LVKDPAK-PDSYVNMSSVIVPHCSYPILMGQIPKRGLEEEFWRAAYNEQV---VMMYVLVGSEDEKY-DFFPKTTGSFLYYGEMFVNVRKVEKMDEERSR
| |. . ..|.| ... .. . . | | ..||| .. .| ||. .| . | ..|..... | .||. |.. . ...|..
lskieeeegsdYinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCerYWpeegeeelefgefevtleeekavdddfli
YTIEVLPNgfSNSVMMNVYVHTGWEPFGVPIRYANTTRSVVDVMNFVKssNGSEKLLVVSKNGCGRAGFFITLGAAFCCLNDNSEP---RIGEIVKAIRS
|..| . ..| ... . .| | ||| . . . . .| .. . . .. |.| |.||.| |.. . |... | . ..| .|
rtLkveaq..kesrkvyqfhYtaWPDhgvPssaksllelielvrelqe..sedaPlvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrk
QRPNAVESIKQYASLYLCLLYYIKKKITV
||. .| . .|| .| ... ...|....
qraalvqtkeqyelvykavaelvqkelei
|
|||||||||
subfamily_PTPN14_pd | Subfamily PTPN14 | 144-406 | 2.3e-15 | 51.4 | In-house | 19-298 (300) | alignment | ||
Range on Protein: 144-406
Range on HMM: 19-298/300.0
KLDASQTRPEYIDVCVATKANIENCTVWKKNLAKNQ-TDVYPILDATLVKDPAKP--DSYVNMSSVIVPHCS--YPILMGQIPKRGLEEEFWRAAYNEQV
||. .. .|| . . . ... ..| ||. || | |. . |.| . |.| ||. |. .. . .. | | . ..||. ....|
kleegkvfteyeripkkredallstaklpenaeknrfkdvlPyednrvelsptkenstgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgv
VMMYVLVGS-E---DEKYDFFPKT--TGSFLYYGEMFVNVRKVEKMDEE-RSRYTIEVLPNGFSNSVMMNVYvhTGWEPFGVP------IRYANTTRSVV
.. | . | . . .|||. . . .|. | . .|. | . .... || . .|.. | | | ||| . | . .||
qlivmlteeeedgkeksfkyfPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqy..tDWpdhgvPeDvkgflsyLeevqsvr
DVMNFVKS-SNGSEKLLVVSKNGCGRAGFFITLGAAFCCLNDNSEPRIGEIVKAIRSQRPNAVESIKQYASLYLCLLYYIKK
.| .. . . .|| .| ||.| |. .|. | | | .... .| || |... || .| |. |.|.
rktnseveskeskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLreqrmllvqtlaqYkfvYkvlikylkn
|
|||||||||
subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 200-402 | 4.9e-15 | 50.8 | In-house | 55-253 (284) | alignment | ||
Range on Protein: 200-402
Range on HMM: 55-253/284.0
YVNMSSVIVPHCSYPILMGQIPKRGLEEEFWRAAYNEQVVMMYVLVgsEDEKYDFFPKTTGsfLYYGEMFVNVRKVEKMDEeRSRYTIEVLPNGFSN-SV
|.| | . . | |. ..||| .. .. . .| .| ...|. . .... |.| ||. .| ||. .| .
yinasfitGyqrkdkyiatqGPldntladfWrmiweyncstivllt..kdkcsqywplkiv..ikeerfkvkvdsveesee.yvvrdielsedgkekdir
MMNVYVHTGWEPFGVPIRYANTTRSVVDVMNFVKSSNGSEKLLVVSKNGCGRAGFFITLGAAFCCLNDNSEPRIGEIVKAIRSQRPNAVESIKQYASLYL
.. . || ||| .. | | | . . |. ....| |.||.| .|.| . . ..... . ..|. .| ||.. |... || .|
kirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrtgvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiys
CLLY
||
alle
|
|||||||||
subfamily_Ptp69D_pd | Subfamily Ptp69D | 174-407 | 5.9e-15 | 50.2 | In-house | 48-289 (307) | alignment | ||
Range on Protein: 174-407
Range on HMM: 48-289/307.0
NLAKNQTDVYPILDATLVKDP----AKPDSYVNMSSVIVPHCSYPILMGQIPKRGLEEEFWRAAYnEQVVMMYVLVGSEDEKYD-----FFPKTtgSFLY
|. ||. . | | || . . .|.| | .. . . .. | | . ..||| || | . |.. ..|| . ..|.
nalknRyedikafDktRvkLkkingkedsdYinasfikgykekkkfiaaqdPveatigDfWRmia.eqevtlivmlsnlteknrkkcakYWpie..devq
YGEMFVNVRKVEKMDEERSRyTIEVLPNG-----FSNSVMMNVYVHTGWEPFGVPIRYANTTRSVVDVMNFVKSSngSEKLLVVSKNGCGRAGFFITLGA
||.. |.. . ||... | ...| .. .| . | .|||. . || . . | . | . ..| ..| ||.| |..|
ygdilvklvseekhsdyiiR.eldvskkkeesgevedsrkvvqyhytgWkDskvPevargllklieqvrelykln..rsPivvhCsaGvgrsgifvalds
AFCCLNDNSEPRIGEIVKAIRSQRPNAVESIKQYASLYLCLLYYIKKK
. |. . . | |.|| .||||. |.|..|| || || |...
llqqlkaedkvdifetvkdLrsqRnllvqsleqYvflyralldyssyg
|
|||||||||
subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 200-402 | 6.1e-15 | 50.3 | In-house | 91-289 (319) | alignment | ||
Range on Protein: 200-402
Range on HMM: 91-289/319.0
YVNMSSVIVPHCSYPILMGQIPKRGLEEEFWRAAYNEQVVMMYVLVgsEDEKYDFFPKTTgsFLYYGEMFVNVRKVEKMDEeRSRYTIEVLPNGFSN-SV
|.| | | . | |. ..||| .. .. . .| .| ...|. . .... |.| ||. .| ||. .| .
yinasfvtGyqrkdkyiaaqGPldntladfWrmiweyncstivllt..kdkcsqywplki..vikeerfkvkvdsveetae.yvvrdielsedgkekdir
MMNVYVHTGWEPFGVPIRYANTTRSVVDVMNFVKSSNGSEKLLVVSKNGCGRAGFFITLGAAFCCLNDNSEPRIGEIVKAIRSQRPNAVESIKQYASLYL
.. . || ||| .. | | | . . |. ....| |.||.| .|.| . . ..... . ..|. .| ||.. |... || .|
kitqfhflGwpdvGvpdypsdlmrlvkkvrhltskenhranivvhcsaGvGrtGvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiys
CLLY
||
alle
|
|||||||||
subfamily_PTPN3_pd | Subfamily PTPN3 | 171-400 | 8.8e-15 | 49.4 | In-house | 38-271 (280) | alignment | ||
Range on Protein: 171-400
Range on HMM: 38-271/280.0
WKKNLAKNQ-TDVYPiLDATLVKDPAKPDSYVNMSSVIVPHCSYPI----LMGQIPKRGLEEEFWRAAYNEQVVMM---YVLVGSEDEK-YDFFPKTTGS
.||.||. |. | ||| || . . |.| . | . | . . | | . ..||. ..... .. || . | . ..|.|. .
kpenlsknryrdilp.ydatrvklkesetdyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqksslivmlttlverGrvkChqyWPetede
fLYYGEMFVNVRKVEKMDEERSRyTIEVLPNGFSNSVMMNVYVHTGWEPFGVPIRYANTTRSVVDVMNFVKSSngSEKLLVVSKNGCGRAGFFITLGAAF
| |||. |...| .. . | . . . ... .. .. | ||| |. . | | . ... .| ..| | ||.| .|.| |.
.leygefsvkcekedetksyvlr.elvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklrsgk..eePvvvhCsaGigrtGvlilletal
CCLNDNSEPRIGEIVKAIRSQRPNAVESIKQYASLYLCL
. .. . . . .||. .| || . |.. .|| . ..
alieaaepvypldivrtmrdqramlvqtasqykfvCeai
|
|||||||||
subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 161-407 | 1.5e-14 | 48.8 | In-house | 30-274 (288) | alignment | ||
Range on Protein: 161-407
Range on HMM: 30-274/288.0
TKANIENCTVWKKNLAKNQTDVYPILDATLVKDPAKPDSYVNMSsvIVPHCSY--PILMGQIPKRGLEEEFWRAAYNE---QVVMMYVLVGSEDEK-YDF
.|.|. ... .| .... . | |.| || || |.. .|. | .. | | .| ||.|. .. .||. |. || ..
neasidiidsfianptrdryenlprcditrvklsddpdfyiaan..vvssakykrrlicaqaPlngtieelWkmllesdveyivmlcellekGkeksaey
FPKTTGSFLYYGEMfVNVRKVEKMDEERSR-YTIEVLPNGFSNSVMMNVYVHTGWEPFGVPIRYANTTRsvvdVMNFVksSNGSEKLLVVSKNGCGRAGF
|| | .| . .| |... | .. .. . ..|.. . |. ||| | | ... . . . ..| |..| ||.|
fPsklGekarigrl.ctvvkkkradidklvkvsllriskegeekvivkilhlleWdddgvPenylsplr....llevl..kslqkPivvhssaGvGrtgt
FITL--GAAFCCLNDNSepRIGEIVKAIRSQRPNAVESIKQYASLYLCLLYYIKKK
.| . .|.|.. | .... | .| .|... .|| .. |.|... |
lililialeslrlddfl..girsllaklreerfkaiqtemqylyvhrcvleelllk
|
|||||||||
subfamily_PTPN13_pd | Subfamily PTPN13 | 145-405 | 2.5e-14 | 48.2 | In-house | 8-270 (273) | alignment | ||
Range on Protein: 145-405
Range on HMM: 8-270/273.0
LDASQTRPEYIDVCVaTKaNIENCTVWKK--NLAKNQ-TDVYPIlDATLVKDPAKPDsYVNMSSVI--VPHCSYPILMGQIPKRGLEEEFWRAAYNEQvV
|| | |. .. | ...|.| || | .||. .| |. |.| || .. |.| | . | . | .. | | ..||. .. . .
ldqqqPaeefkelre.lk.pldtcevgkkkenkdknryrnvlPy.detrvklgdegg.yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqk.a
MMYVLVGSEDEK-----YDFFPKTTGSFLYYGE-MFVNVRKVEKMDEERSRyTIEVLPNGFSNSVMMNVYVHTGWEPFGVPIRYANTTRSVVDVMNFVKs
. ..| .| || ..|..... | . . |.. ||.|.|. | ...| . ..| . . | ||| |. . | | .. .
eviamvtlekekgkvkchrywPesknkklkvsnrlevellkvqkldgfvvr.alavkdsesgesrevahlnfvkwPdhgvPssaaellqfvaevrrlqt.
snGSEKLLVVSKNGCGRAGFFITLGAAFCCLNDNSEPRIGEIVKAIRSQRPNAVESIKQYASLYLCLLYYIK
. ..| | ||.| .||. ... .. . | . |||. .| || | . .|| | .|. .|
..dagPivvhcsaGiGrsGtlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykailevlk
|
|||||||||
subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 199-401 | 4.5e-14 | 47.1 | In-house | 78-276 (315) | alignment | ||
Range on Protein: 199-401
Range on HMM: 78-276/315.0
SYVNMSSVIVPHCSYPILMGQIPKRGLEEEFWRAAYNEQ---VVMMYVLVGSEDEKYD-FFPKTtgsFLYYGEMFVNVRKvEkmdEERSRYTIEVLPNGF
||| . . . | |. ..||| ..|. .||. || | .| . ..| . ||.. | .. | | ..||. | |
dyvnanfidGynkkrryiaaqgpnvasvkdfwrlvfeedigkivmltnlvegekrkaekywpdk...kviyGkitvtrks.e...evnteytvrtlsvvf
SNSVMMNVYV-HTGWEPFGVPIRYANTTRSVVDVMNFVKSSNgsEKLLVVSKNGCGRAGFFITLGAAFCCLNDNSEPRIGEIVKAIRSQRPNAVESIKQY
. . | . .| | ||| . . |. . ..| ..| ..| ||.| |||| | . .. . . .... .|..| ..|....||
gdnirevvqlhytswpdmgvpkytiplmnlirtvkqhhtnsv..gaivvhcsaGvGrtGtfitldavldqaeaenaidvynfitgvrqnrikmvqvaeqy
ASLYLCLL
.| ||
qfiydall
|
|||||||||
0041856 | (Phosphotyrosine protein) phosphatases II | 174-411 | 6.6e-14 | 47.4 | In-house | 1-178 (182) | alignment | ||
Range on Protein: 174-411
Range on HMM: 1-178/182.0
NLAKNQTDVYPILDATLvkdpakPDSYVNMSSVIVPHCSYPILMGQIPKRGLEEEFWRAAYNEQVVMMYVLVgseDEKYDFfpkttgsflyygemfvnvr
|| || . .. | .. . .|.| . .. .. . ... | | . ..|.| ..... . | .| |.
nldknrysdilpydhsr......dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt...eelywp...................
kvekmdeersrytievlpN-GfsnSVMMNVYVHTGWEPFGVPIryantTRSVVDVMNFVKSsnGSEKLLVVSKNGCGRAGFFITLGAAFCClndnsEPRI
. . |....|. .||| .....| .. |.. ... || . |.||.|... . .. . .
..................ell...erlgiqylylpwpDhgvpd.....ldelldfieevle..eggpvlVHCsaGvgRtgtlvaaylmkkl.....gvsl
GEIVKAIRSQRPNAVESIKQYASLYLCLLYYIKKKITVP
|.|| .||.||..|.. || |.|.||.... |.|.|
eeavklvrsrRpgmvitpnqyfflqlallellllkktrp
|
|||||||||
subfamily_CG7180_pd | Subfamily CG7180 | 198-404 | 7.2e-14 | 46.1 | In-house | 70-290 (296) | alignment | ||
Range on Protein: 198-404
Range on HMM: 70-290/296.0
DSYVNMSSVIVPHCSYPILMGQIPKRGLEEEFWRAAYNEQVVMMYVLVGSEDEK--Y-DFFPKTTgsFLYYGEMFVNVRKVEKMDEERSRyTIEVLPN--
. |.| . | .. . ||. .|||| |.|.. . || | . | ...|... |||.||.. ..... . ..| |. . .
sdYinavyvdsflkkkeyivteapkketvdefWrlvydeeisavvvLtktfdfakmypsywpnks..keqygeifveiveekqyanlkir.tfkltkkiv
--G-----F-SNSVMMNVYVHTGWEP-FGVPIR---YANTTRSVVDVMNFVKSSNGSEKLLVVSKNGCGRAGFFITLGAAFCCLNDNSEPRIGEIVKAIR
. . .. .. | || ||. . . | | ... |. . . ..|||..| .|.| .... |. .. . | . | || .|
alteqekqvkaetRivklfqlteWeledkvPlstnalielrrrvrlwrekvdedpeegPvvvvssdGasRsGvylaidanlelvekeeevdvFeavktlr
SQRPNAVESIKQYASLYLCLLYYI
.||. ||....| .| || ..
rsRpqLvenveeYkyiYdvlleav
|
|||||||||
subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 224-424 | 1.6e-13 | 45.4 | In-house | 100-302 (318) | alignment | ||
Range on Protein: 224-424
Range on HMM: 100-302/318.0
GLEEEFWRAAYNEQvVMMYVLVGSE----DEKYDFFPKTTGSfLYYGEMFVNVRKVEKMDEERSRyTIEVLPNGFSNSVMMNVYVHTGWEPFGVPIRYAN
|.||| .. . .. |.. | .| . . || ||.. |.... .... | ...| .. ..| .. | .| | ||| |.
etieDfWrmvWeqn.savivmltqeeergkakvhryWPskgs.rsygklvvelkeevelsdyvlr.efkvtrteeeesrqvrqyhytsWpdegvpesgas
TTRSVVDVMNfVKSSNGSEKLLVVSKNGCGRAGFFITLGAAFCCLNDNSEPRIGEIVKAIRSQRPNAVESIKQYASLYLCLLYYIKKKITV--PEGLQQK
| .| . .. ..| . ..| | ||.| ||.. . ..... . ..|| .|.||. | .|| .| || ... | . |...
lldlvrqvsk.aqqksgagpivvhCsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqtedqyefiydvllealasgdtevdasdlrsr
VEDLKRG
...|..
irelreq
|
|||||||||
subfamily_PTPN9_pd | Subfamily PTPN9 | 139-406 | 2.2e-13 | 44.9 | In-house | 7-292 (297) | alignment | ||
Range on Protein: 139-406
Range on HMM: 7-292/297.0
VAYIGKLDASQTRPEYIDVCVATKANIENCTVWKKNLAKNQTDVYPILDATLVKDPAKP----DSYVNMSSVIVPHCSYPILMGQIPKRGLEEEFWRAAY
|||. . . . . ||... . . ... . || ||. .| | |. . .. |.| . | . .. | | . ..||| .
vayvkekgkrGlskeyaeirnepveGtflasklranleknrytdvlcydetrvvlakvdedeasdyinanfvdGykqkkafiatqGplkktvsdfWrmvW
NEQVV---MMYVLVGSEDEK-YDFFPKTTGSFLYYGEMFVNVRKVEKMDEER-SRYTIEVLPNGFSNsvMMNVYVHTGWEPFGVPIRY------ANTTRS
...|. |. .| | ..|....| .|.. |.. .||.... . . ..|. .. | . . ..| .||| .. |.
eqevlvivmttrvvergrlkcgqyWpleeessaefgdlsvsnveveeeedykvrvleiknvkteesr..kvthfqflsWPdyGvPssaaslldvlekvre
----VVDVMNFV-KSSNGSEKLLVVSKNGCGRAGFFITLGAAFCCLNDNSEPRIGEIVKAIRSQRPNAVESIKQYASLYLCLLYYIKK
.|. . | ..| | ||.| |||| . |.. . . | || .|.|| .. .||. ||..| | ..
kqalavkelgdewkghpsgPPivvhcsaGiGrtGtfitldiclsrleevgtvdvvetvkllrtqrafsiqtpeqyefcylavleyale
|
|||||||||
subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 161-406 | 1.1e-12 | 42.6 | In-house | 21-261 (267) | alignment | ||
Range on Protein: 161-406
Range on HMM: 21-261/267.0
TKANIeNCTVWKKNLAKNQTDVYPILDATLVKDPAKPDSYVNMSSVIVPHCSYPILMGQIPKRGLEEEFWRAAYNEQVVMMYVL-VGSEDEKYDFFPKTT
|...| . . .|| ..|. | | | | | . |.| | | . .. |.| . .|. ...| .. .| .|. |.|
tssti.sqsiaeknqernrlddnlpyddtrvilrtkeeeyinasyvegyktknafivtqdplkntitdfltvihdqkvpvivlltkvftdnirlfwPPkm
GSFLYYGEMFVNvRKVEKmdeERSRYTIEVLPNGFSNSVMMNVYVHTgWEPFGVPIRYANTTRSVVDVMNFVKSSNGSEKLLVVSKNGCGRAGFFITLGA
| | .. |. . .|| | | | .| | | || .. .. . . . .. .. . ||. |.| ..| ||.| |... .
gqakkyqdltve.hslek...eendyqiitlelkfknesahnvtlyy.ykkwnintnnkpylkplfgilaknqlengnrPlvvacsdGvGrsGtflvids
AFCCLNDNSEPRIGEIVKAIRSQRPNAVESIKQYASLYLCLLYYIKK
. . .. | . .. |||||. |.. .| .. | | .
qleraktegvsdifdflrkirsqriglvdtkeryiyihellaeyaeg
|
|||||||||
subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 196-406 | 1.2e-12 | 42.4 | In-house | 71-285 (290) | alignment | ||
Range on Protein: 196-406
Range on HMM: 71-285/290.0
KPD---SYVNMSSVIVPHCSYPILMGQIPKRGLEEEFWRAAYNEQVVMMYVLVG-SEDEK---YDFFPKTtGSFLyYGEMFVNVRKVEKMDeERSRYTIE
..| .|.| . . . .. .. | | .||. ..|.| .. .|. |..| . ..|.. .. |||. ... . |... | . ..|
hkDCtneyinAcyikgykekkqyiatqgpvsntlvdFWkliwqekvtiivmltniieegkvkCqqYWpds.dtka.ygefsikllneetln.eyierkle
VLPNGF-SNSVMMNVYVHTGWEPFGvPIRYANTTRSVVDVMNFVKSSNGSEKLLVVSKNGCGRAGFFITLGAAFCCLNDNSEPRIGEIVKAIRSQRPNAV
| . .. .. | | |.. | . .| .|. |. . .| . ..| .. ||.. |... . . . . ...| |.|.|. |
vknknsagakqsvtqyqitnwdstg.kvtnpqtillvieemyktqrkrgntsivvHCSdtvgrsavfcaaattinkcktegvidvfqvlksqRiqkpgsv
ESIKQYASLYLCLLYYIKK
.. .|| .. .| |...
qtvqqyqgifqivltylds
|
|||||||||
subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 176-403 | 1.7e-12 | 41.6 | In-house | 58-282 (290) | alignment | ||
Range on Protein: 176-403
Range on HMM: 58-282/290.0
AKNQTDVYPILDATLV--KDpAKPDSYVNMSSVivPHCSYPILMGQIPKRGLEEEFWRAAYNEQVVMMYV---LVGSEDEK-YDFFPKTTGSFLYYGEMF
||. . | | | || . || | .... | . . ..|| .|.| .. . |. | ...|.. | | .||.
kknrykdvvcndktrvilkd.GydGdyvhanyv..kGlkamfiltqGalkdtvidiwrmvlqekvaaivmlceliedGkakceqyypekeGevltfGeit
VNVRKVEKMDEERSRYTIEVLPNGFSNSVMMNVYVHTGWEPFGVpiryANTTRSVVDVMNFVKSSNGSekLLVVSKNGCGRAGFFITLGAAFCCLNDNSE
| . .. |.. . |. | . ... . | | |..| ... .. .. .| . | | ||.| |... .. .| | |
vlcseeddkdaniikktlsvrdkdsGkehklkhlkikswpdksv....alstlallrtlrilrkasGp..vvvhcsaGiGrtGtfvaievglqilldGke
PRIGEIVKAIRSQRPNAVESIKQYASLYLCLLYY
.. ..|.|.| | |.|. || | || .
ldlldlvralrnsrlnsvqvdiqylalveilldl
|
|||||||||
subfamily_PTPRG_pd | Subfamily PTPRG | 216-422 | 2.2e-12 | 41.0 | In-house | 94-303 (563) | alignment | ||
Range on Protein: 216-422
Range on HMM: 94-303/563.0
LMGQIPKRGLEEEFWRAAYNEQ---VVMMYVLVGSEDEKYDFF-PKttGSFLYYGEMFVNVRKVEKMDEERSR-YTIEV--LPNGFS--NSVMMNVYVHT
.. | | . . ||| .... .||. || .. .| | . || . ||.. |. . |.. .| .|. | .. . . .. | |
iatqgplkdtfddFWrmiWeqnvaiivmitnlvergrrkcdvYWPk..desetygalqvtlieeevlalytvrtlviknlklkkkkqcdteklvrqyhyt
GWEPFGVPIRYANTTRSVVDVMNFVKSSNGseKLLVVSKNGCGRAGFFITLGAAFCCLNDNSEPRIGEIVKAIRSQRPNAVESIKQYASLYLCLLYYIKK
| ||| . |. |. | ..| ..| ||.| .| | . ..... . ...| ||.||.. |... || |. || |.
kWPdhgvPehslpvLifvkkssaankaeaG..PivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvqteEqYiflhdalleaias
KITvpEGLQQKVEDLK
| | | |...||.||
ket..ellaeqveelk
|
|||||||||
subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 198-407 | 2.4e-12 | 41.6 | In-house | 69-279 (281) | alignment | ||
Range on Protein: 198-407
Range on HMM: 69-279/281.0
DSYVNMSSVIVPH--CSYPILMGQIPKrgLEEEFWRAAYNEQVVMMyVLVGSEDEK-----YDFFPKTTgSFLYYGEMFVNVRKVEKMDEErSRYTIEVl
|.| . | . | . | .|. ..||. ....| .. |.| | |. . ..| . | | ||.. |. . |. . . ....
tDYinanfvpgykgekeyiatqgPvPa..slvafWqmvweqkvsai.vmvtreieagklkChrYWPddn.selkygdvtvkstaeeekaty.ierkfkl.
PNGFSNSVMMNVYVHTGWEPFGVPiryaNTTRSVVDVMNFVKS---SNGSEKLLVVSKNGCGRAGFFITLGAAFCCL-NDNSEPRIGEIVKAIRSQRPNA
. .... .. .| | ||| .||. ... . |.. .. |.. | ||.| .|.| .. . ....| . ..|. .| .|
eresgetreveqlaytaWPdhGvP....attkellefrkevlkltekktkaplvihCsaGvGrtGtyialDrlvkaveaeleeldvkavvaelrkernlm
VESIKQYASLYLCLLYYIKKK
| .. ||. .|. .| ...|.
vqtvvqyefvykavldaldke
|
|||||||||
subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 191-406 | 3e-12 | 41.1 | In-house | 64-280 (287) | alignment | ||
Range on Protein: 191-406
Range on HMM: 64-280/287.0
VKDPAKPDSYVNMSSVIVPHCSYPILMGQIPKRGLEEEFWRAAYNEQVVMMYVLVG----SEDEKYDFFPKTTGsfLYYGEMFVNVRKVEKMDEeRSRYT
| . . |.| . . . .. .. . | .||. ...| . .|. |. |...|... ...|| ... . |.... .
vllkgehpdyinavfidgykekkafiiaesPmfntarnfWkliddrnvtaivmlcqekendeevcyqyWpeeks..vvlGeyniellneevnag.yierk
IEVLPNG-FSNSVMMNVYVHTGWEPFGVpIRYANTTRSVVDVMNFVKSSNGSEKLLVVSKNGCGRAGFFITLGAAFCCLNDNSEPRIGEIVKAIRSQRPN
.|| .. .. ... | | |. | . .| |.. |. . .| ..| .. ||.. |. . . . . ...| | |.|.
levknknkagdkqqvkqyqitnWdstgk.vtepqtillvieemyktqrkrgntsivvhCsdtvGrsamfcaaattinkckteGviDvfqvlksqriqkpg
AVESIKQYASLYLCLLYYIKK
.| ..|| .. .| |..
svqtveqykfindivleylds
|
|||||||||
subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 167-395 | 5.6e-12 | 40.1 | In-house | 26-257 (283) | alignment | ||
Range on Protein: 167-395
Range on HMM: 26-257/283.0
NCTVWKKNLAKNQTDVYPILDATLVKDPAKPDSYVNMSSVIVPH---CSYPILMGQIPKRGLEEEFWRAAYNEQV---VMMYVLVGSEDEKYD-FFPKtT
.... ..| ||. . | |. ... .|.| . ..| . . .. | | . .||. ..|.. ||. | ...| ..||
diasadenkrknrnqeivpadqwrvelksesrdyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekitaivmltklqedlrikCsqyWPk.r
GSfLYYGEMFVNVRKvEKMDEERSRYTIEVLPNGF-SNSVMMNVYVHTGWepfgvpIRYANttRSVVDVM---NFVKSSNGSEK---LLVVSKNGCGRAG
|| |||. | .|| | . .. . . |. ..... | .| . | . .... . | |.| .| ..| .| ||..
Gs.edyGeftvtlrk.ettsnsfiikelllrvnssakstlllahyqvidW......leyge..qaiinslvkfnkvislqteskkgPivvhCstgiGrta
FFITLGAAFCCLNDNSEPRIGEIVKAIRSQRPNAVESIKQYAS
||.. |. . .| . ..|| .| ||. || . ||
vfiaasasvkdaltesvvdvfavvkimreqrmmavqtldqykl
|
|||||||||
0051429 | (Phosphotyrosine protein) phosphatases II | 215-414 | 1.2e-11 | 40.4 | In-house | 24-235 (272) | alignment | ||
Range on Protein: 215-414
Range on HMM: 24-235/272.0
ILMGQIPKRGLEEEFWRAaYNEQVVMMYVLVGSE---DEKYDFFP-----------KTTGSFLYYGEMFVNVRKVEKMDEERSRYTIEVLPNGFSNSVMM
.. .. | . ...||| ..... . | . | .|.|... .. . || ..| . ..| .. |. . .| . ... ..
lyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseellldyilrellltlllsagearev
NVYVHTGWEPFGVPIRYanttrsVVDVMNFVKSsngSEKLLVVSKNGCGRAGFFITLGAAFCCLNDNSEPR--------IGEIVKAIRSQRPNAVESIKQ
....|.| .||| . ........ . ....|| . |..| |... | .... . |.|. .|.|||.||.. |
mhlhytdwpdhgvpqea......llellellld...ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlyleeaveelraqrpgavqteeq
YASLYLCLLYYIKKKITVPEGL
|. || .|| .... ..|..
ylflyeallellrsllsvraey
|
|||||||||
subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 227-407 | 1.8e-11 | 38.6 | In-house | 87-271 (274) | alignment | ||
Range on Protein: 227-407
Range on HMM: 87-271/274.0
EEFWRAAYNEQV---VMMYVLVGSEDEK-YDFFPKTTGS--FLYYGEMFVNVRKVEKMDEersrYTIEVLPNGFS-NSVMMNVYVHTGWEPFGVPIRYAN
..||| |.|.| ||. | .. .| .||.... ||.. ..|.|. . .. |... | . .. . | .| | .| . .
adfWrmiyqeevqvivmltklkeaneqkCavyfPdaedyeiserygdveikvekivernd....ysvrklvlkylerersvkhywytdWPdhksPddant
TTRSVVDVMNFVKSSNGS-EKLLVVSKNGCGRAGFFITLGAAFCCLNDNSEPRIGEIVKAIRSQRPNAVESIKQYASLYLCLLYYIKKK
. | .| . ...| .| | ||.| ||. | |.... . .|| .| .| |.. .|| .. | | |.
lldlvleveesreeenaklapvvvhCsaGiGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralclylkrl
|
|||||||||
0036282 | (Phosphotyrosine protein) phosphatases II | 215-397 | 2.9e-11 | 38.8 | In-house | 19-163 (174) | alignment | ||
Range on Protein: 215-397
Range on HMM: 19-163/174.0
ILMGQIPKRgleeeFWRAAYNEQVVMMYVLVGSEDEK----YDFFPKttgsflyygemfvnvrkvekmdeersrytievlpNGFSNSVMMNVYVHTGWEP
.. || | . ||. ..... . | .. . ....| . . . . |....|.
liagqgpla.....fwemlkelgittvvmlleekelglykcinywpe..................................lredlerlgiqylylpwpD
FGVPIRYAntTRSVVDVMNFVKSSNGSEKLLVVSKNGCGRAGFFITLGAAFCCLNdNSEPRIGEIVKAIRSQRPNAVESIKQYASLY
.||| ...|. .. . |.... ..|| . |.||.|... . ..| .| . ..|...|.|||..|.. || ||
hgvpdlsi..llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtpsQyrfly
|
|||||||||
subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 193-404 | 3.8e-11 | 37.1 | In-house | 70-279 (439) | alignment | ||
Range on Protein: 193-404
Range on HMM: 70-279/439.0
DPAKPDS-YVNMSSVIVPHCSYPILMGQIPKRGLEEEFWRAAYNEQVVMMYVLVgSEDEKYDFFPKTTGsfLYYGEMFVNVRKVEKMDEERSRyTIEVLP
| | | |.| . . . |.||. ..||| .....| . .| | | ..| . .||.. | | . .. . | . |.
ipgvphshyinanyikGyyddklyiatqgpkkettddfwrlviekktvtivmlt.nlvesykywpsdae..vcygdiavrvdrnielpnyvir.gfkvfn
N--GFSNSVMMNVYVHTGWEPFGVPIRyantTRSVVDVMNFVKSSNGSEK---LLVVSKNGCGRAGFFITLGAAFCCLNDNSEPRIGEIVKAIRSQRPNA
. . . . .. | || . . |.| . ..|.| .|. ..| | ||.| |.| |. |. . . | ||| .| || .
erdttekertvlqfhyiawpdknvpaq....ashvldflrainsandkeeygpvvvhcsagvGrtGtiialdialeqlklenkvdikgivkvlrkqrkqm
VESIKQYASLYLCLLYYI
|... || .| ..| |
vqalcqyvfiynavledi
|
|||||||||
0043147 | (Phosphotyrosine protein) phosphatases II | 198-397 | 7.4e-11 | 37.6 | In-house | 5-154 (172) | alignment | ||
Range on Protein: 198-397
Range on HMM: 5-154/172.0
DSYVNMSSVIVPHCSYPILMGQIPKRGLEEEFWRAAYNEQVVMMYVLVGSedekydffpkttgsflyygemfvnvrkvekmdeersrytievLPNGFSNS
. |.| | . .... ....| | | ..||| ..... . . | . | .. .
sdyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltel..........................................lydpelle
VMMNVYVHTGWEPFGVPirYANTTRSVVDVMNFVKSSNGSEKLLVVSKNGCGRAGFFITLGAAFCCLndnsepRIGEIVKAIRSQRPNAVESIKQYASLY
. | ...|. .||| .. ..... .. . . ... || . |.||.|... . ..| . |.|. .|..||.||.. || ||
rlgiqylylpwpDhgvp..llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylmllgl......sleeavalvrekRpgavqnpsqyrfly
|
|||||||||
0046846 | (Phosphotyrosine protein) phosphatases II | 263-406 | 7.4e-11 | 37.6 | In-house | 77-175 (176) | alignment | ||
Range on Protein: 263-406
Range on HMM: 77-175/176.0
LyygemfvnvrkvekmdeersrytievlpngfsnsvmmnVYVHTGWEPFGVPIRyaNTTRSVVDVMNFVKSSNgsEKLLVVSKNGCGRAGFFITlgaafC
. | |..|. .||| . .... .. . ... .. || . |.||.| .. .
i......................................qylhlpwpDhgvpdl..elllellefirealkeg..gpvlVHCsaGigRtgtlva.....a
CLND-NSEPRIGEIVKAIRSQRP-NAVESIKQYASLYLCLLYYIKK
| . . |... .|.||| .||.. .|| || ..|...||
yllelekglsveealalvreqRplgavqtpeQyrflyefellllkk
|
|||||||||
0049772 | (Phosphotyrosine protein) phosphatases II | 264-415 | 1.2e-10 | 37.1 | In-house | 167-291 (314) | alignment | ||
Range on Protein: 264-415
Range on HMM: 167-291/314.0
YygemfvnvrkvekmdeersrytiEVL--PNGFSNSVmmNVYVHTGWEPFGVPiryanTTRSVVDVMNFVKSSNGSEKLLVVSKNGCGRAGFFITlgAAF
|.| |. |.. . |... .. ...| ... . ....|... . ...|| | |.||.| |.. ||.
k.......................eelydpelferlg..ikylripvpDgsap.....lledfdeflefieeadkggpvlvHCkaGkgRtgtfvv..aay
CCLNDnSEpRIGEIVKAIRSQRP-----NAVESIKQYASLYLCLLYYIKKKITVPEGLQ
... . |... .|..|| ...|. .|| . .||.|.|......| |.
lmkll.gv.sleealedvrlkRpinpnpgfieqleqyefilealleylkflkkfyeyle
|
|||||||||
subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 200-405 | 1.7e-10 | 35.4 | In-house | 61-271 (285) | alignment | ||
Range on Protein: 200-405
Range on HMM: 61-271/285.0
YVNMSSVIVPHCSYP-ILMGQIPKRGLEEEFWRAAYNEQV---VMMYVLVGSEDEKY-DFFPKTTGSFLYYGEMFVNVRKVE--KMDE-ERSRYTIEVLP
|. | . .| . | | .||. |.|.. .|. |. || ..|. | . .|. . . ... . |.
yihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyypeklgevvkfgkyeitlteckeeaiagtilnaltvinte
NGFSNSVMMNvYVHTGWEPFGVPiryANTTRSVVDVMNFVKSSNGSEKLLVV-SKNGCGRAGFFITLGAAFCCLNDNSEPRIGEIVKAIRSQRPNAVESI
. |. . || .|. | | . . .| .... ..|| | || ..| | ||. |. . | . .| . . .||. .|. | .||.|
dasseplymn.hvqvpwwpdqla...pedarpmielykwvkkvnpkekpicvhcsagvgrtatfvgidyatirimenpniemldivremramrfqavqsh
KQYASLYLCLLYYIK
|. ||. |. |.
mqflflyvvlmeyfi
|
|||||||||
subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 174-404 | 1.9e-10 | 34.7 | In-house | 45-236 (392) | alignment | ||
Range on Protein: 174-404
Range on HMM: 45-236/392.0
NLAKNQTD-VYPI--LDATL-VKDPAKPDSYVNMSSVIVPHCSYPILMGQIPKRGLEEEFWRAAYNEQVVMMYVLVGSED-Ekydffpkttgsflyygem
|| ||. . . |. | | | . |.| | . .. . | |. ..||| ..|.| . .. .. .
nlkknryknilpydsarvkleviddipdsdylnasyipsfdnekayiasqgpnaaslddfwrmvfqenvttiamvtklkegd..................
fvnvrkvekmdeersrytievlpNGFSNSvMMNVYVHTGWEPFGVPiryaNTTRSVVDVMNFVKSSNGSEK--LLVVSKNGCGRAGFFITLGAAFCCLND
.| .. . . | | .|| . | |.. ... ||. |. |.. | ||.| |.. . . .
.......................kgddar.tvaqfhftewPdkdvp....khtssllkfikevkadfGqythpliihcsagvgrtgvvisidsvvahakk
NSEPRIGEIVKAIRSQRPNAVESIKQYASLYLCLLYYI
. ..| || .|| |.. .||| .| ..| .
trmvdvfnfvtnirrkrpymvqtkeqyafiygavledl
|
|||||||||
0048076 | (Phosphotyrosine protein) phosphatases II | 263-403 | 1.9e-10 | 36.1 | In-house | 11-142 (145) | alignment | ||
Range on Protein: 263-403
Range on HMM: 11-142/145.0
LYYGEMFvNVRKVEKMDEERSRYTIEVLPNGFSNSVMMNVYVHTGWEPFGVPiryaNTTRSVVDVMNFVKSS---NgsEKLLVVSKNGCGRAGFFItlgA
||.| . .....| . . .. . . .. . . |....|. .||| . .. . ....|... . .. || . |.||.|... |
lylgslp.taldlellkdlgittvlnltselellerlgiqylylpwpDhgvp....dllellleflefieealkeg..gpvlVHCsaGvgRtgtlv...a
AFCCLNDNsePRIGEIVKAIRSQRPNAVESIKQYASLYLCLLYY
|...| . . |... .|||||.||.. |. ||...|..
aylmlllg..vsleealelvrsqrpgavpnpgqlrflyefelel
|
|||||||||
subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 219-397 | 2.2e-10 | 35.2 | In-house | 51-232 (237) | alignment | ||
Range on Protein: 219-397
Range on HMM: 51-232/237.0
QIPKRGLEEEFWRAAYNEQ---VVMMYVLVGSEDEK-YDFFPKTTgSFLYYGEMFVNVRKVEKMDEERSRYTIEVLPNGFSNSVMMNVYVHTGWEPFGVP
| | ..||. ..|. .||. |. ....| ....|.| || . | ..| |.. . | . . . .. | | | |||
qgplesscddfwqmvwqekcsvivmltgliegnelkchkywpstd.qpaaygvltvslkkkeefsdytvrslllskrltlkevrlihqyqftswpdrgvp
IRYANTTRSVVDVMNFVKSSNGSEKLLVVSKNGCGRAGFFITLGAAFCCLNDNSEPRIGEIVKAIRSQRPNAVESIKQYASLY
. | | ...| . . | .. | ||.| |. . | . ... | . |..| .|| ... || ..
qqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlrqakekkvvdiynyvysieedrpyiiqtkdqyvfih
|
|||||||||
subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 227-401 | 2.6e-10 | 34.9 | In-house | 65-237 (239) | alignment | ||
Range on Protein: 227-401
Range on HMM: 65-237/239.0
EEFWRAAYNEQVV---MMYVLV-GSEDEKYDFFPKTTGSflyYGEMFVNVRKVEKMDEERSRyTIEVLPNGFSNSVMMNVYVHTGWEPFGVPiRYANTTR
.||| ..|. . |. |. | . . ....| .| | .. | .|| | . . | |. . | .. . | | | ||| .|| .
gdfwrmmwqerrcvivmltglieghkkkchqywpdstsk...ycnlrvtlrktevfadyiir.tfvmsqvgqteeryvyqyhftvwpdkgvp.qyatavl
SVVDVMNfVKSSNGSEKLLVVSKNGCGRAGFFITLGAAFCCLNDNSEPRIGEIVKAIRSQRPNAVESIKQYASLYLCLL
. . | |. .. | ||.| |. . | . . . | . ||||| .|| |.. .|| ..|..|
glrrkit.kdslpgarpwvihcsagvgrtgaflvidamlrqakkqktvdifnyvkairedrphmvqtseqyvfihlavl
|
|||||||||
subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 227-401 | 2.9e-10 | 34.7 | In-house | 66-238 (239) | alignment | ||
Range on Protein: 227-401
Range on HMM: 66-238/239.0
EEFWRAAYNEQVV---MMYVLV-GSEDEKYDFFPKTTGSflyYGEMFVNVRKVEKMDEERSRyTIEVLPNGFSNSVMMNVYVHTGWEPFGVPiRYANTTR
.||| ..|. . |. |. | . . ....| .| | .. | .|| | . . | |. . | .. . | | | ||| .|| .
gdfwrmmwqerrcvivmltglieghkkkchqywpdstsk...ycnlrvtlrktevfadyiir.tfvmsqvgqteeryvyqyhftvwpdkgvp.qyatavl
SVVDVMNfVKSSNGSEKLLVVSKNGCGRAGFFITLGAAFCCLNDNSEPRIGEIVKAIRSQRPNAVESIKQYASLYLCLL
. . | |. .. | ||.| |. . | . . . | . ||||| .|| |.. .|| ..|..|
glrrkit.kdslpgarpwvihcsagvgrtgaflvidamlrqakkqktvdifnyvkairedrphmvqtseqyvfihlavl
|
|||||||||
subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 217-407 | 6.7e-10 | 33.2 | In-house | 94-284 (301) | alignment | ||
Range on Protein: 217-407
Range on HMM: 94-284/301.0
MGQIPKRGLEEEFWRAA--YN-EQVVMMYVLVGSEDEKY-DFFPKTTGSFLYYGEMFVNVRKVEKM-DEERSRYTIEVLPN--GFSNSVMMnVYVHTGWE
| | . |.|| |. |..||. | . || ...| .... | | ..... |.. ... |. |.|| |. .. | .. |
atqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkisekldigrfkikiknkelilnkkiskrtlevedstgkfatrtvt.hyqysewt
PFGVPIRYANTtrsvVDVMNFVKSSNgsEKLLVVSKNGCGRAGFFITLGAAFCCLNDNSEPRIGEIVKAIRSQRPNAVESIKQYASLYLCLLYYIKKK
||| .|.. |.|..|| |. . ..| .| ||. ||. .. . . . | .| .| .| |.| .| . | .| . |.
drgvPkshael....fdlmelvkkse..kPivvhcsaGiGrsvafigteylareveadptieltealkhlrehrwngvqtnsqlywmtlGtvyrlike
|
|||||||||
0048179 | (Phosphotyrosine protein) phosphatases II | 263-398 | 1.2e-09 | 33.5 | In-house | 11-139 (144) | alignment | ||
Range on Protein: 263-398
Range on HMM: 11-139/144.0
LYYGEMFvNVRKVEKMDEERSRYTIEVLPNGFSNSVMMN--VYVHTGWEPFGVPiryaNTTRSVVDVMNFVKSS-NGSEKLLVVSKNGCGRAGFFItlgA
||.| . ....| . . .. | . .. ... . |.|..|. .||| . . . ....|... . ... || . |.||.|... |
lylgslp.taldlellkklgittvinlteeyepefleregiqylhlpwpDhgvp....dllellleflefieealeeggpvlVHCsaGvgRtgtlv...a
AFCCLNDNsePRIGEIVKAIRSQRPNAVESIKQYASLYL
|. .. . . |... .||.||.||.. |. |..
aylmkklg..lsleealalvrsrrpgavpnpgqlrfLle
|
|||||||||
subfamily_PTPN6_pd | Subfamily PTPN6 | 227-409 | 1.3e-09 | 32.4 | In-house | 112-302 (306) | alignment | ||
Range on Protein: 227-409
Range on HMM: 112-302/306.0
EEFWRAAYNEQVVMMyVLVGSEDEK-----YDFFPKTTGSFLyYGEMFVNVRKVEKMDEERSRyTIEVLP-NGFSNSVMMNVYVHTGWEPFGVPIRYANT
..||| ...|. .. |.. | |. . ..|... . ||.. |. . ..... | .. | . ... . | .. | |||
sdFWrmvwqensrvi.vmttkevErgkekCarYWPdeeekee.yGkisvtnvseksladYilR.elsvskkkkkkeerevfqyhfksWPdhgvpkdpgav
TRSVVDVMNFVKSSN--GSEKLLVVSKNGCGRAGFFITLGAAFCCLNDN---SEPRIGEIVKAIRSQRPNAVESIKQYASLYLCLLYYIKKKIT
. || . .... . ..| .| || | || . . .. . . | ..|| .|.|| | .|| .| . .||..| .
LdfledvnrkqeeleeaeagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqteqqykfvykaikkyietkkk
|
|||||||||
subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 171-404 | 1.6e-09 | 31.8 | In-house | 44-279 (303) | alignment | ||
Range on Protein: 171-404
Range on HMM: 44-279/303.0
WKKNLAKNQTDVYPILDATLVKdpAKPDSYVNMSSVIVPhCSYPILMGQIPKRGLEEEFWRAAYNEQVVM-MYVLVGSEDEKY--D-FFPKTtGSFLYYG
. ||. ||. || . || ||. | . . .| .. |.| .||. ...| . .| || .|. | ||. || .
fvknmdknrfvdvicldhskvk..lsdssyihasyleld.sskkailtqlplshtaadfwqmiieqkvkcvlllltdseydklggdsvfprn.qdflkfe
EMFVNVRKVEKMDEeRSRYTIEVL--PNGFSNSvMMNVYVHTGWEPFGVPIR-YANTTRSVVDVMNFVKSSNGSEKLLVVSKNGCGRAGFFITLGAAFCC
| .. | . ... ... || || .| .. |. . | .| .. . . .. ... |. . .| |||||| | . .|
ersirvgefkrvel.gdgwvlkvlsvsngdyks.flhvhhykawphnsipsdgspkfvkqiwqlqsvlrkysdstptvymslsgcgragtfalfetahls
LND-NSEPRIGEIVKAIRSQRPNAVESIKQYASLYLCLLYYI
| . .. . .. .| | ||. . |.. .| | ..
lhseqasldlvkclenvrngrlhavqnlsqfsvvytllaehv
|
|||||||||
0049260 | (Phosphotyrosine protein) phosphatases II | 212-397 | 2.1e-09 | 32.8 | In-house | 8-143 (152) | alignment | ||
Range on Protein: 212-397
Range on HMM: 8-143/152.0
SYPILMGQIPKRGLEEEFWRAAYNEQVVMMYVLVGSEDEKYDFFPKTTgsflyygemfvnvrkvekmdeersrytievlpngfsnsvmmnVYVHTGWEPF
..... .| | . ..||| .. .. .| .. ....... | |. |. .
pfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi..........................................qylhlpwpDh
GVPIRYANTTRsVVDVMNFVkSSNGSEKLLVVSKNGCGRAGFFITLGAAFcclndnSEPRIGEIVKAIRSQRPNAVESIKQYASLY
||| ....... . ... || . |.||.|... . . |.|. .|..||.||.. |. ||
gvpdlsqlllf.lllfiekl.aldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpgqlrfly
|
|||||||||
subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 196-405 | 3.4e-09 | 30.8 | In-house | 68-294 (301) | alignment | ||
Range on Protein: 196-405
Range on HMM: 68-294/301.0
KPDSYVNMSSVIVPHCSYPILMGQIPKRGLEEEFWRAAYNEQVVMMYVLVGSEDE----KYDFFPKTTGSFLYYGEMFVNVRKVEKMDEERS--------
. .|.| | . . . | | . .||| ..|..| . .. . ... . ..|... . ..|.. | . . . .
cqreyinasyidgysekkkfiaaqgpmkktlvdfWrliwqekpvsivmvtnlkegtkskceqywpnseaeseefgpftvtlvneqvyPdfvirqlnvkiq
-----RYTIEVLPNGFS-NSVMMNVYVHTGWEPFGVpIRYANTTRSVVDVMNFVKSSNGSEKLLVVSKNGCGRAGFFITLGAAFCCLNDNSEPRIGEIVK
|.. . . .| . . | | || .| .| |.| . . . | ...| .. .|.| .... . . . ...|
dgsnngyierkfkvksdksswdvlqlqvtdWpqdGv.vreprtvLqviddvihrqqkigggpvvVHCSdtVsrsGvYcsvsiglEQckaegVVdvfqvtk
AIRSQRPNAVESIKQYASLYLCLLYYIK
|.| ..| || ..|| |.| . |..
avrrskpgaVtTLeqytsiydvidmylq
|
|||||||||
subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 172-407 | 1.3e-08 | 28.9 | In-house | 53-292 (305) | alignment | ||
Range on Protein: 172-407
Range on HMM: 53-292/305.0
KKNLAKNQTDVYPILDATLVK--DPAkPDSYVNMSSVIVPHCS-YPILMGQIPKRGLEEEFWRAA---YNEQVVMMYVLVGSEDEKY-DFFPKTTGSFL-
. . .||. . | | ..|| .|. | |. | .| .. | | .||| ||.||. | | ...| . | |
diaitknryqdvpcqdqsavkldkps.psdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkveqivmlcktvelgklkcaqywpaaqgekle
-YYGEMFVNVRKVEKMDEErSRYTIEVLPNGFSNSVMMNVY--VHTGWEPFGVPIryanTTRSVVDVMNFVKSSNGseKLLVVSKNGCGRAGFFITLGAA
| . || |. . . | .| .| . | | | | ||| . .... .. |. ..| | ||.| ...
lksgivvenvsgskpmerd.aeiqitllnltysgdqkmsvrhlqwtewpdrgvpp....ckltslellsairgskv..pivvhcsagigrtgtivaieyi
FCCLNDNSE-PRIGEIVKAIRSQRPNAVESIKQYASLYLCLLYYIKKK
. . .| . | . |.|||.| || .... || .. .| |. .|
lekiaenkpcppmpelvkalrdqrafsiqndvqylfihrvmlnyflek
|
|||||||||
subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 176-405 | 1.3e-08 | 28.9 | In-house | 40-278 (287) | alignment | ||
Range on Protein: 176-405
Range on HMM: 40-278/287.0
AKN-QTDVYPILDA--TLVKDPAKPDSYVNMSSVIVPHCSYPILMGQIPKRGLEEEFWRAAYNEQVVMMYVL---VGSEDEK-YDFFPKTTGSFLYYGEM
|| .|| || |. |.... . .|.| | . . | | .|||| ..... . .. | | | ..|. . |
kknryadvlPiddtrvllsaegelGsdyinanyvasytddeafiaaqgPiaatvrdfwravletrsasvitmtreveearlkcykywPerevPmrvGGys
FVNVrKVEKMDEERSRYTIEVLPNGFSNSVMMNVYVHTGWEPFGVPIRYANTTRSVVDV---MNFVKSSNGSEKLLVVSKNGCGRAGFFITLGAAFCCLN
| . . .... | . .. .. .. ... . | ... | |.|| .. ..... |.| . | ||.| .... . |.
vvll.dydikePeygvralrlidletrearvvkqldllswPdkvlaPtavglirfvldvkqhielardasevGPlvvhddvGiGrsGillatlvlvsrle
DNSEPRIGEIVKAIRSQRPNAVESIKQYASLYLCLLYYIK
| . . .| .| .| | .. |. || | | |
dlGrvdvaavvirlreyraalvqavvqlrllyealvtyyk
|
|||||||||
0044763 | (Phosphotyrosine protein) phosphatases II | 205-406 | 5.3e-08 | 28.2 | In-house | 24-173 (178) | alignment | ||
Range on Protein: 205-406
Range on HMM: 24-173/178.0
SVIVPHcsyPILMGQIPkrgleEEFWRAAYNEQVVMmYVLVGSEDEK-----YDFFPKTTGsflyygemfvnvrkvekmdeersrytievlpngfsnsvm
| |.|. .|... | ..... ... . . | . .|.| . .|. .|
seilpg...lylgslpp.....addlellkelgith.ivnlteelelgflkcdpywpeeag.......................................
mNVYVHTGWEPFGVPIrYANTTRSVVDVMNFVKSSNGsEKLLVVSKNGCGRAGFFItlgAAFC---ClndnsEPRIGEIVKAIRSQRPnAVESIKQYASL
|.|.... .||| .. .|. .. . ...| .. || . | ||.| .. ||. . . |... .|..|| .|.. |. |
.iqylhipipDhgvpd.llehflefvefieealdekg.gpvlVHCsaGvgRsgtlv...aaylmkkl.....glsleeaielvrerRp.ivpnpgqlrqL
YLCLLYYIKK
|.. |.. |.
yefelrllke
|
|||||||||
subfamily_PTPN1_pd | Subfamily PTPN1 | 174-417 | 7.1e-08 | 26.5 | In-house | 32-283 (290) | alignment | ||
Range on Protein: 174-417
Range on HMM: 32-283/290.0
NLAKN-QTDVYPIlDATLVKDPAKPDSYVNMSSVIVPHCSYPILMGQIPKRGLEEEFWRAAYNEQ---VVMMYVLVGSEDEK-YDFFPKTTG-SFLYYGE
| ..| || | | . .| . |.| | | ... .. | | . ||. .... |||. .| | | ....|. . | . .
nrnlnryrdvspy.dhsrikleradndyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvvekeqikcaqywPqgeeekellled
MFVNVRKVEKmdEERSRYTIEVL--PN-GFSNSVMMNVYVHTGWEPFGVPIRYANTTRSVVDVMNFVKSSNGSEKLLVVSKNGCGRAGFFITLGAAFCCL
. ..|. ... |..| ||...| | .. . . .| | |||| |. . . .| . |. .. | ||.| |. . . . .
tklkvklise..erksyytvrllelenlktqetreilhfhyttwpdfgvpespaaflkflfkvresGslssdvGpavihcsaGiGrsGtfclvdtclvli
NDNSE---PRIGEIVKAIRSQRPNAVESIKQYASLYLCLLYYIKkKITVPEGLQQK
... . | . . ..|..| . .| || .| .| .|. . .|..
ekkddlssvdikkvllelrkyrlGliqtadqlrfsylaileGak.vikgdssvqkr
|
|||||||||
subfamily_egg_pd | Subfamily egg | 216-414 | 7.6e-08 | 26.4 | In-house | 86-280 (307) | alignment | ||
Range on Protein: 216-414
Range on HMM: 86-280/307.0
LMGQIPKRGLEEEFWRAAYNEQVVMMYVLVG---SEDEKYdFFPKTTGSFLYY--GEMFVNVRKVEKMDEERSRYTIEVLpNGFSnsvMMNVYVhtgwEP
.. | | . ..||| ..|.| . .| || .| ..||. | . | . .. ||.. . | | | | . .. |
ilaqaplkntvddfwrmvfqeevqyivmltsrkesercey.ywpkaesdslvtvpGslrienlkvdskadplfrvtklkl.vGgd...deerfl....eh
FGVPIRYANTTRSVVDVMNFVKssNGSEKLLVVSKNGCGRAGFFITLGAAFCCLNDN--SEPRIGEIVKAIRSQRPNAVESIKQYASLYLCLLYYIKKKI
. ..... | . |. .. | |. .| ...|. .|. .... |.. | . . |. .| .|. .|||. .| .| .|.... |
wqgdvnnssdvysplrvlrklr..nlskpvvvqdilGvskaatlvaieiallsllrGpitkslvlravvflrlrrrlsvesvllylfvyrlvlfffrdvi
TVPEGL
. |
gsakel
|
|||||||||
subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 177-417 | 2.1e-07 | 25.0 | In-house | 51-300 (305) | alignment | ||
Range on Protein: 177-417
Range on HMM: 51-300/305.0
KNQTDVYPILDATLVK-DPAKPDSYVNMSSVIVPHCSYPILMGQIPKRGLEEEFWRAAYNEQVVMMYVLVGSED----EKYDFFPKTTGSFLYYGEMF--
||. || || ... | |. | | . .. | | .|| ....| ....| . ...|. . | . |
knrykdvgcldnnrvklegpwpheyihanyvstptnpkrfictqaplektcadfwymclqdkveaifmlcnllekgakkcleyfaskdkdvlefeekgqk
--VNVRKVEKM---DEERS--RYTIEVLPNGFSNSVMMNVYVHTGWEPFGVPiryaNTTRSVVDVMNFVKSSNGSekLLVVSKNGCGRAGFFITLGAAFC
| . ... .. .. . |. |. ... .. | | ||| . ....... ..| | . | | ||.| . | .
isvkfessvtlkfrkdakakvtetvlviegpgekarkvthyhwidwpdrgvp....aadlailellekarpskgp..ivvhcsagigrtgsvvmleyild
-CLNDNSEPRIGEIVKAIRSQRPNAVESIKQYASLYLCLLYYIKKKITVPEGLQQK
|. . |.. || || |.... .|| .. .| |..|| . | ..
qllagqiiedtdkilqkireqrnnsiqtdaqylfvhqvilnyfrkkklldeevkea
|
|||||||||
subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 220-410 | 2.4e-07 | 24.5 | In-house | 98-294 (302) | alignment | ||
Range on Protein: 220-410
Range on HMM: 98-294/302.0
IPKRGLEEEFWRAA--YNEQVVM-MYVLVGSEDEKY-DFFPKTTGSFLYYGEMFVNVRKVEKM-DE-----ERSRYTIEVLPNGFSNSVM--MNVYVHTG
.||. | .| || .|. . .| .|..|. ... . | | .|. |. .|.. .| . ||.|. . . | ... ....
vpkkstlekhwalieqynvaivvqlcsfvedeekkcaeyysdkvggelkfgrytvktvsvktdleeftdkksfklytveiknekkkkkvkktvdilafsa
WEPFGVPiryaNTTRSVVDVMNFVKSSNgsEKLLVVSKNGCGRAGFFIT--LGAAFCCLNDNSEprIGEIVKAIRSQRPNAVESIKQYASLYLCLLYYIK
| | | . . . .|...| .| ...|| .| ||.| ... | .| .. .. . .||. .|. | || . .| | ||. .
wpdhGap....keaytaldilkfcesyk..knvlvhcsaGvGrtGtlvaikyGiqlcskkkvtd..llsivlpvrqcryGavqdeqqliylllcvtkglm
KKITV
.|..|
ekagv
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 292-401 | 2.6e-07 | 24.4 | In-house | 84-191 (440) | alignment | ||
Range on Protein: 292-401
Range on HMM: 84-191/440.0
NGFsNSVMMNVYVHTGWEPFGVPiRYANTTRSVVDVMNFVKSSNGSEKLLVVSKNGCGRAGFFITLGAAFCCLNDNSEPRIGEIVKAIRSQRPNAVESIK
|| .| .. | . || ||| ..| ... .| . |. ||| . |.||.| |.. . . . . . | .....|..||. |.. .
ngi.esrtlkqyhyqgwpdkgvp.kfagpvlkmiqdvnesqekagngpllvhcsagagrtgviiavdsilreakrsdqidifsfinsmrnnrpqmvqtpe
QYASLYLCLL
||| .. ..|
qyafvheavl
|
|||||||||
subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 167-403 | 4.4e-07 | 23.8 | In-house | 28-268 (281) | alignment | ||
Range on Protein: 167-403
Range on HMM: 28-268/281.0
NCTVWKK--NLAKNQTDVYPILDATLV----KDPAKP-DSYVNMSSVIVPHCSYPILMGQIPKRGLEEEFWRAAYNEQ---VVMMYVLVGSEDEKY-DFF
|||... | ||. | || . | | | | |. . | .. | ||. .||| ..|. .||. .. .. || ..|
lctvfnqpvnnkknrylnipcldisrvqlkvkmpnknstdyihanyirspflkrgyiltqgpkketradfwrmiwqenttaivmlcqfletnrekcaeyf
PKTTGSFLYYGEMFVNVrkvEKMDEERSRYTIEVLPNGFSNSVMMNVYVHTGWEPFGVPiryaNTTRSVVDVMNFVKSsnGSEKLLVVSKNGCGRAGFFI
|. . | . .. |. | ..| | . .. .. .. | . || ... .. .. ... | .. | ||.| ..
prnahcclqfdklsvsy...edstvnkslvttrlnlsyegetrlithwlwkewpdwqvp....essevmlkilrkira..rstppvihcsagvgrsgtlm
TLGAAFCCLND-NSEPRIGEIVKAIRS-QRPNAVESIKQYASLYLCLLYY
.. |. . . | | .|| .| | .|....|| .. || .
aveialqsihshftlpdikqivshlrvtgraasvqtlqqymliwkvlldf
|
|||||||||
subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 198-401 | 5.5e-07 | 24.0 | In-house | 46-257 (290) | alignment | ||
Range on Protein: 198-401
Range on HMM: 46-257/290.0
DSYVNMSSVIVPHCSYPILMgQIPKR-------GLEEEFWRAAYNE---QVVMMYVLVGSEDEKYD-----FFPKTTGSFLYYGEMFVNVRKVEKMDEER
| |. . |..|. ||. | |. |.|| .| .| ||||. . .. . ..|.. | | .. . |. . || |.
ddyiHAnrvtcpnglrlilt.qsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCakYvpesvgeelkfkgltvkCkskekeddve
SRyTIEVLPNGfSNSVMMNVYVHTGWEPFGVPiryaNTTRSVVDVMNFVKSSNGseKLLVVSKNGCGRAGFFITLGAAFCCLN-DNSEPRIGEIVKAIRS
| ...| .. . .. . ||.. |. ..|.........|| |. .| ..| | . .. .. . ... . ...||.|.
tR.elvvkfdd.eeeftvtHsllkgWnklnvq....edtktllsliqkvkaskt..pvivHcvdGiSrsAalaaiilgyQkiaetsgsvkledvlkalrk
QRPNAVESIKQYASLYLC-LL
|| .|. | ...| .|
qralaitsalelafvdagivl
|
|||||||||
subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 167-405 | 1.1e-06 | 23.0 | In-house | 34-278 (307) | alignment | ||
Range on Protein: 167-405
Range on HMM: 34-278/307.0
NCTVWKKNLAKNQTDVYPILDAT--LVKDPAKPDSYVNMSSVIVPHCSYPILMGQIPKRGLEEEFWRAAYNEQVVMMYVL---VGSEDE-KYDFFPKTTG
. .. | ||. . . | . .|| . |. . . .. | |. .|| | .|.| . .| . ...| |
tveafsantdknryqdvkcqdkgrivvkfdglasdyihanylgiaikpkkficaqgplentqysfwamaiqekvesvimlckvielakikceqywpleeg
SFLYYGEM----FVNVRKVEKMDEERSRYTIEVLPNGFS-NSVMMNVYVHTGWEPFGVPiryaNTTrsvVDVMNFVKSSNGSEK-LLVVSKNGCGRAGFF
| .|| |. ..|. . . | .. .| .. . . | ||| .. . .|.... .. . ..| | ||.|
qklvfgeapntisvanlgakklapdedlinvttlkvdwaqksrtiqhlqwenwpdrgvp....qin...ltainlleavrydtnpvvvhcsaGvGrsGti
ITLGAAFCC-LNDNSEPRIGEIVKAIRSQRPNAVESIKQYASLYLCLLYYIK
... .. . ..|. .||||. |... || |. || |
vaislvqdkmiaGinckdmkklveelrsqrhyaiqteaqylylhrvlleyfl
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 200-403 | 1.4e-06 | 22.4 | In-house | 61-294 (297) | alignment | ||
Range on Protein: 200-403
Range on HMM: 61-294/297.0
YVNMSSVIVPHCSYPI--LMGQIPKRGLEEEFWRAAYNEQVVMM---YVL-VGSEDEKYDFFPKTTGSFLYYGEMFVNVrkVEKMDEERSRYTIEVLPNG
|.| |. |. .. .. | | . ..||. ....| .. | . | . ..|.. . | |.. |. . .. .| | . |
yinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrdkcapywpsvvqerlkagdvvvef..lsstsdefdrviltelqli
F-SNSVMMNVYVHTGWEPFGVP------IRY-A---------NTTRSVVD---------VMNFVKSSNGSEKLLVVSKNGCGRAGFFITLGAAFCCLNDN
. |.| ... . .| ||| |. | ..|. . . . ||| | ||.| . . | .
yrsesrvvrhvqflswpdhGvpsdledlvrfqaqvcscciavpmmlalvemftamvflqleslraemprnayllvhcsaGvGrsGvvvlsdvilaklrkk
SEPRIGEIVKAIRSQRPNAVESIKQYASLYLCLLYY
| . |.. .|.||. |....|. || |
ripdvaailsilreqrarlvqtleqfellydavlkk
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 339-406 | 6.4e-06 | 20.0 | In-house | 249-317 (319) | alignment | ||
Range on Protein: 339-406
Range on HMM: 249-317/319.0
KLLVVSKNGCGRAGFFITLGAAFCCLNDN-SEPRIGEIVKAIRSQRPNAVESIKQYASLYLCLLYYIKK
| | .| ||.| |. |. |... | ..| .| .| .|| ...||. .| | | ||
PlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefiykvlseyakk
|