Gene DDB_G0292880 in Dictyostelium discoideum

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family DSP
Subfamily DSP-unclassified
Protein sequence
ID Type Fasta BLAST phosphatome Note
DdisP007_AA protein Get Run
DdisP007_AA_364-500 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
0044763 (Phosphotyrosine protein) phosphatases II 204-507 4.2e-31 103.4 In-house 23-174 (178) alignment
Range on Protein: 204-507
Range on HMM: 23-174/178.0
GVEIIPHLYLGSFLAAKNSEWLLEANVTKIVNVTSEVPSYFlskkekendkiisekdeidsfivdddedenededdedidddddddddddddenedened
 .||.|.|||||. .|.. |.| | ..| |||.|.|.. .|                                                           
aseilpglylgslppaddlellkelgithivnlteelelgf...........................................................

edgnqdenvdigdekdkemkdlpitpspnekkeeniemkdnddkdqemkdspaaaaatsstnekkeeenvemkdeltinnipikidqvnEDVDSEKIKEL
                                                                                         .. | .  .| 
.........................................................................................lkcdpywpeea

SIKYLRISISDSFRSKIENYFQEAIDFINQGN-VDGsekSNVLIHCKQGRSRSPSIVIAYLMSNEKWTLEKAFNHVSSVSPknLTVNDGFKKKLMDLEME
.|.||.| |.|.    .  .|.|...||..    .|   ..||.||. |..||...|.||||   ...||.|...| .. |     |.|. . |...|..
giqylhipipDhgvpdllehflefvefieealdekg...gpvlVHCsaGvgRsgtlvaaylmkklglsleeaielvrerRp..ivpnpgqlrqLyefelr

LFGSN
|.. .
llkes

DSPc Dual specificity phosphatase, catalytic domain 373-500 3.2e-26 86.8 Pfam-A 8-131 (133) alignment
Range on Protein: 373-500
Range on HMM: 8-131/133.0
VEMKDELTINNIPIKIDQVNEDVDSEKIKELSIKYLRISISDSFRSKIENYFQEAIDFINQGnvdGSEKSNVLIHCKQGRSRSPSIVIAYLMSNEKWTLE
 .... |....| . |.  .|   . .||. .|.|||| . |.  .||.....||..||..     ... .||.||. | |||....|||||. ....|.
taslalleklgitlvinvtkevpnnnaikkseieylripvedetetkiskeleeavefieka...eqkgkkvlVHCqaGisRSatliiaYlmktknlsln

KAFNHVSSVSpKNLTVNDGFKKKLMDLE
.|...|..   ...  |.||...|...|
eAyefvkerr.skispnagflrqLleye

DSPc Dual specificity phosphatase, catalytic domain 373-500 3.2e-26 86.8 In-house 8-131 (133) alignment
Range on Protein: 373-500
Range on HMM: 8-131/133.0
VEMKDELTINNIPIKIDQVNEDVDSEKIKELSIKYLRISISDSFRSKIENYFQEAIDFINQGnvdGSEKSNVLIHCKQGRSRSPSIVIAYLMSNEKWTLE
 .... |....| . |.  .|   . .||. .|.|||| . |.  .||.....||..||..     ... .||.||. | |||....|||||. ....|.
taslalleklgitlvinvtkevpnnnaikkseieylripvedetetkiskeleeavefieka...eqkgkkvlVHCqaGisRSatliiaYlmktknlsln

KAFNHVSSVSpKNLTVNDGFKKKLMDLE
.|...|..   ...  |.||...|...|
eAyefvkerr.skispnagflrqLleye

subfamily_DSP3_pd Subfamily DSP3 394-503 6e-25 81.8 In-house 52-157 (162) alignment
Range on Protein: 394-503
Range on HMM: 52-157/162.0
DVDSEKIKELSIKYLRISISDSFRSKIENYFQEAIDFINQGNVDgsEKSNVLIHCKQGRSRSPSIVIAYLMSNEKWTLEKAFNHVSSvsPKNLTVNDGFK
| ..|  |.|.|||| . ..|........||..| .||..   .  ... ||.||..| |||. .|.||||  .| || .| ..| .   .... |.|| 
dtgaefykdleikylGlevdDvpefdlskyFetaakfidealsq..kegkvlvhcvvGvsRsatlvlayLmirrkmtlveairtvrk..kReilPneGFl

KKLMDLEMEL
|.|..|..||
kqLaeldeel

subfamily_DSP14_pd Subfamily DSP14 375-513 9.3e-25 81.4 In-house 23-154 (157) alignment
Range on Protein: 375-513
Range on HMM: 23-154/157.0
MKDELTINNIPIKIDQVNEDVDsEKIKElsIKYLRISISDSFRSKIENYFQEAIDFINQGNVDGsekSNVLIHCKQGRSRSPSIVIAYLMSNEKWTLEKA
 |..|. ..| . |.   | .. .|.|.  |..... ..|. ..|. ..|.|..| |.. . .|    ..|.||. |.||| |...||||  || .|..|
skellkkkkitliinvtvelpn.tklkd..iervkvpveDnpeaklakhfdevadkieevkkkg...gktlvhCvaGvSRSAslclaylmkyeklsLrea

FNHVSSVSPKnLTVNDGFKKKLMDLEMELFGSNSINFFD
...| |. |  .  | || |.|.|.| .|.|..|..  |
yklvksaRpi.irPNvGFwkqlidyEkklkgkssvkmvd

0049772 (Phosphotyrosine protein) phosphatases II 379-503 1.5e-24 82.8 In-house 158-273 (314) alignment
Range on Protein: 379-503
Range on HMM: 158-273/314.0
L--------TinnipikidqvNEDVDSEKIKELSIKYLRISISDsFRSKIENYFQEAIDFINQGnvdgSEKSNVLIHCKQGRSRSPS-IVIAYLMSNEKW
.                    .|  | |. ..| |||||| ..| .   ....|.|...||..     .....||.||| |..|... .|.||||.  ..
ptaadlellk...........eelydpelferlgikylripvpD.gsaplledfdeflefieea....dkggpvlvHCkaGkgRtgtfvvaaylmkllgv

TLEKAFNHVSSVSPknLTVNDGFKKKLMDLEMEL
.||.|...| .  |     |.|| . |...|..|
sleealedvrlkRp..inpnpgfieqleqyefil

subfamily_DSP19_pd Subfamily DSP19 397-503 1.5e-24 81.1 In-house 48-150 (152) alignment
Range on Protein: 397-503
Range on HMM: 48-150/152.0
SEKIKELSIKYLRISISDSFRSKIENYFQEAIDFINQGNVDGsekSNVLIHCKQGRSRSPSIVIAYLMSNEKWTLEKAFNHVSSVSPkNLTVNDGFKKKL
 ...    ..|| |.| |    .. .|..||.|||...         ||.||. |.|||.|.||||||..|. .||.|.. | .. | ... |.|| |.|
vpnvfpkdftylsieilDlpetdllsylkealdFieearskd...gavlvHCnAGvSRsasvviaylmkkeelsleealelvrearp.cikPneGFikqL

MDLEMEL
 ..|.||
keyeael

subfamily_DSP12_pd Subfamily DSP12 374-497 2.5e-24 80.5 In-house 21-137 (155) alignment
Range on Protein: 374-497
Range on HMM: 21-137/155.0
EMKDELTINNIpikIDQVNEDVDSEKIKELSIKYLRISISDSFRSKIENYFQEAIDFINQGNvdgSEKSNVLIHCKQGRSRSPSIVIAYLMSNEKWTLEK
|...|| |...   .  ..|.....|.|.  .... | | |. .  | ....||.|||...    .|. .||.||. | ||| .||||||| .||. |||
ellkelkithv...lsvikeelpehklkkgkvstkfiqilDepeediLshldeavdFieeal...eeegavlvHCqagvSRSvtiviAYlmkkeklslek

AFNHVSSVSPkNLTVNDGFKKKLM
|.. |....| . . |.|| . | 
Alklvkekkp.eiepNegFleQLk

subfamily_DSP10_pd Subfamily DSP10 390-504 2.8e-24 79.8 In-house 45-154 (159) alignment
Range on Protein: 390-504
Range on HMM: 45-154/159.0
QVNEDVDSEKIKeLSIKYLRISISDSFRSKIENYFQEAIDFINQGNvdgSEKSNVLIHCKQGRSRSPSIVIAYLMSNEKWTLEKAFNHVSSVSPkNLTVN
 |  .|  |  .  ..|| || .||. . ....||.||..||.. .   .. |.||.||. | ||| ..|||||| . . .|..|...|..  |  .. |
nvttsvPnefee.ealkYkripvsDtskqnlkqyfeealefieear...kkgsrvLvhCqaGisrsatvviaYlmkhlnlslndaykfvkekrp.iisPn

DGFKKKLMDLEMELF
 .|  .|...| || 
LnfmGqLlefekeln

subfamily_DSP6_pd Subfamily DSP6 367-503 4.8e-23 75.4 In-house 26-154 (158) alignment
Range on Protein: 367-503
Range on HMM: 26-154/158.0
KKEEENVEMKDELTINNIpikiDQVNEDVDSEKIKELSIKYLRISISDSFRSKIENYFQEAIDFINQGNvdgSEKSNVLIHCKQGRSRSPSIVIAYLMSN
.|. .|.|. ..|.|. .      | .....   .. ..|||.|.|.| .  .. ..| |||.||...    |.||.||.||  | |||  ...||||..
akdasnlevlkklkikyv....lnvtsnlpnkfeesgelkylqipiedhlsqnlakffPeaiefidear...skkskvlvhClaGisrsvtvtlaylmkk

EKWTLEKAFNHVSSVSpKNLTVNDGFKKKLMDLEMEL
.. .|..|.. | .    |.. |  | ..|.| | .|
lalslndaydlvkkrk.snisPnfnfmgqlldfersl

0041856 (Phosphotyrosine protein) phosphatases II 203-505 7.6e-23 76.5 In-house 18-174 (182) alignment
Range on Protein: 203-505
Range on HMM: 18-174/182.0
KGVEIIPHLYLGSFLA--------------AKNSEWLLEANVTKIVNVTseVPSYFLskkekendkiisekdeidsfivdddedenededdedidddddd
   .| ..|||||. |              |.. ..| | ..| |||.|   . |.                                            
dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt..eelywp...........................................

dddddddenedenededgnqdenvdigdekdkemkdlpitpspnekkeeniemkdnddkdqemkdspaaaaatsstnekkeeenvemkdeltinnipiki
                                                                                                    
....................................................................................................

dqvnedvdsEKIKELSIKYLRISISDSFRSKienyFQEAIDFINQGNVdgsEKSNVLIHCKQGRSRSPSIVIAYLMSNEKWTLEKAFNHVSSVSPK-NLT
         |. . | |.||.... |         ..|..|||.. .    |. .||.||. |..|....|.||||   ...||.|...| |  |.   |
.........ellerlgiqylylpwpDhgvpd....ldelldfieevle...eggpvlVHCsaGvgRtgtlvaaylmkklgvsleeavklvrsrRpgmvit

VNDGFKKKLMDLEMELFG
 | .|   |. ||. |..
pnqyfflqlallellllk

PTPc_motif_SM00404 372-500 9.3e-23 75.7 In-house 19-138 (140) alignment
Range on Protein: 372-500
Range on HMM: 19-138/140.0
NVEMKDELTINNIPIKIDQVNEDvdsekIKELSIKYLRISISDSFRSKIENYFQEAIDFINQGnvdGSEKSNVLIHCKQGRSRSPSIVIAYLMSNEKWTL
| .....| |  .   ...|. .      .. ....|.| ..|.  .|. .|.....|||..     ... .||.||. | ||| ...|||||. ....|
npallkklgithvinvteevslt.....kensgfqilqiplddnekdklskyldkvldfiena...ekkggkvlVHCqaGvSRSatliiaYlmryrqlsl

EKAFNHVSSVSpKNLTVNDGFKKKLMDLE
..|.. |..   ...  | .|...|...|
aeayefvkerR.piispnlnfvrqLieye

subfamily_DSP8_pd Subfamily DSP8 377-503 1.5e-21 70.6 In-house 34-154 (159) alignment
Range on Protein: 377-503
Range on HMM: 34-154/159.0
DELTINNIPIKIDQVNEDVDSEKIKELSikYLRISISDSFRSKIENYFQEAIDFINQGNvdgSEKSNVLIHCKQGRSRSPSIVIAYLMSNEKWTLEKAFN
. |. ..|   .   |.....|..||    .||. . |..  |. ..|.....||.. .   ||...||.|.  |.|||....|||.| . . .|..|..
ellsklgisyvlnasnscpkleelkesk..flrvPvkDkydekllpwfdksvefidkak...sengrvlvhvlaGisrsatvaiayimktlemsldeayr

HVSSVSpKNLTVNDGFKKKLMDLEMEL
.| .   . .  |  | ..|.. | ||
fvkekr.ptispnlnflgqLleyekel

subfamily_DSP1_pd Subfamily DSP1 400-503 3.5e-21 70.0 In-house 57-156 (163) alignment
Range on Protein: 400-503
Range on HMM: 57-156/163.0
IKELSIKYLRISISDSFRSKIENYFQEAIDFINQGNvdgSEKSNVLIHCKQGRSRSPSIVIAYLMSNEKWTLEKAFNHVSSVSPkNLTVNDGFKKKLMDL
. |   .| .. ..|| .  |  .|.|.|.||.. .   ...  |||||..| ||| ....||||......||.||. | .. .     | ||...|.. 
vfedlfeYkklkleDspkadislvfeeviefidevk...kknGkvlihCqaGisRsstlclaylmktkrvsleeafdfvkqrRs.iisPnagFvlqLlny

EMEL
| .|
ekkl

0046846 (Phosphotyrosine protein) phosphatases II 205-505 3.8e-21 71.1 In-house 13-174 (176) alignment
Range on Protein: 205-505
Range on HMM: 13-174/176.0
VEIIPHLYLGSFL----------AAKNSEWLLEANVTKIVNVTSEV-------PSYFLSKKEKENdkiisekdeidsfivdddedenededdediddddd
..|...|.|||.            |.. |.|.|...| .||.|.||       | |.   .. .                                    
dyinanlilgsrpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgi...................................

ddddddddenedenededgnqdenvdigdekdkemkdlpitpspnekkeeniemkdnddkdqemkdspaaaaatsstnekkeeenvemkdeltinnipik
                                                                                                    
....................................................................................................

idqvnedvdsekikelsiKYLRISISDSFRSKIeNYFQEAIDFINQGNVDGsekSNVLIHCKQGRSRSPSIVIAYLMSN-EKWTLEKAFNHVSSVSPKNL
                  .||.. . |     . ....|...||..   .|    .||.||. |..|.. .|.|||.     ...|.|. .| .. |.. 
..................qylhlpwpDhgvpdl.elllellefirealkeg...gpvlVHCsaGigRtgtlvaayllelekglsveealalvreqRplga

TVNDGFKKKLMDLEMELFG
  .... . |.. |..|..
vqtpeQyrflyefellllk

0051082 (Phosphotyrosine protein) phosphatases II 206-498 8.3e-21 69.6 In-house 10-148 (151) alignment
Range on Protein: 206-498
Range on HMM: 10-148/151.0
EIIPHLYLGSFLAAKNSEWLLEANVTKIVNVTSEVPSYFLSKKEKENDkiisekdeidsfivdddedenededdedidddddddddddddenedeneded
 . ..||..... | . |.| | ... |||..||.. ... .  .|..                                                    
yvtgglyrsggpladflellkelgiktivnlrseeergycpeylpelg....................................................

gnqdenvdigdekdkemkdlpitpspnekkeeniemkdnddkdqemkdspaaaaatsstnekkeeenvemkdeltinnipikidqvnedvdsekikelsI
                                                                                                   |
...................................................................................................i

KYLRISISDSFRSKIENYFQEAIDFINQGNVdgSEKSNVLIHCKQGRSRSPSIVIAYLMSnEKWTLEKAFNHVSSVSPKNLTVNDGFKKKLMD
..|.| | |    ... .|.....|... .    .. .||.||. |..|.  .|..|||  ....||.|.... .  |   . |..| . |..
evlhipildwpdpglplsfdavleflellld..kkngpvlvHCsaGkgRTGtlvalylml.lgvsleealeeyrlkrpgvvqpnqqflfqlfa

0043147 (Phosphotyrosine protein) phosphatases II 205-481 3e-20 68.1 In-house 20-139 (172) alignment
Range on Protein: 205-481
Range on HMM: 20-139/172.0
VEIIPHLYLGSFLAAKNSEWLLEANVTKIVNVTSEvpsyflskkekendkiisekdeidsfivdddedenededdedidddddddddddddenedenede
 ..|........  |.. . | | ..| |||.|..                                                                 
drfiatqgplrntladfwrmlkelgithivnltel.................................................................

dgnqdenvdigdekdkemkdlpitpspnekkeeniemkdnddkdqemkdspaaaaatsstnekkeeenvemkdeltinnipikidqvneDVDSEKIKELS
                                                                                          .| |. ..| 
.........................................................................................lydpellerlg

IKYLRISISDSFRSkIENYFQEAIDFINQGNvDGSEKSNVLIHCKQGRSRSPSIVIAYLMSnEKWTLEKAFNHVSSV
|.||.... |     . ....|...||..     |..  ||.||. | .|.. .|.||||  ....||.|...| . 
iqylylpwpDhgvp.llellleflefidell.alspggpvlVHCsaGvgRtgtlvaaylml.lglsleeavalvrek

0048076 (Phosphotyrosine protein) phosphatases II 391-504 3.3e-19 64.4 In-house 34-143 (145) alignment
Range on Protein: 391-504
Range on HMM: 34-143/145.0
VNEDVDSEKIKELSIKYLRISISDSFRSKIENYFQEAIDFINQGNVDGsekSNVLIHCKQGRSRSPSIVIAYLMSNEKWTLEKAFNHVSSVSPKnLTVND
.|   . |  ..| |.||.... |     . ....|...||..   .|    .||.||. |..|....|.||||  ....||.|...| |  |.    |.
lnltselellerlgiqylylpwpDhgvpdllellleflefieealkeg...gpvlVHCsaGvgRtgtlvaaylmlllgvsleealelvrsqrpg.avpnp

GFKKKLMDLEMELF
|. . |...|.||.
gqlrflyefelell

subfamily_Slingshot_pd Subfamily Slingshot 391-499 3.8e-19 62.7 In-house 51-153 (169) alignment
Range on Protein: 391-499
Range on HMM: 51-153/169.0
VNEDVDSekIKELSIKYLRISISDSFRSKIENYFQEAIDFINQGNvdgSEKSNVLIHCKQGRSRSPSIVIAYLMSNEKWTLEKAFNHVSSVSpKNLTVND
| ...|.    . ...||.|.. |. .... .|..|. .||..     ...|.||.||| | ||| |.|||| | . ...||.|...| .   . .  |.
vtkeidn..ffpekfeylnirvydeeetdllkywnetykfiekak...kkgskvlvhckmGvsrsastviayamkeyglsleealeyvkerr.svikPnk

GFKKKLMDL
|| |.|   
gflkqleey

0048179 (Phosphotyrosine protein) phosphatases II 391-500 8.2e-19 63.2 In-house 36-141 (144) alignment
Range on Protein: 391-500
Range on HMM: 36-141/144.0
VNEDVDSEKIKELSIKYLRISISDSFRSKIENYFQEAIDFINQGNVdgsEKSNVLIHCKQGRSRSPSIVIAYLMSNEKWTLEKAFNHVSSVSPkNLTVND
..|. . |  .   |.||.... |     . ....|...||..      |. .||.||. |..|....|.||||  ....||.|...| |  | .   |.
lteeyepefleregiqylhlpwpDhgvpdllellleflefieeale...eggpvlVHCsaGvgRtgtlvaaylmkklglsleealalvrsrrp.gavpnp

GFKKKLMDLE
|. . |...|
gqlrfLleye

0049260 (Phosphotyrosine protein) phosphatases II 204-483 9.2e-19 63.1 In-house 8-130 (152) alignment
Range on Protein: 204-483
Range on HMM: 8-130/152.0
GVEIIPHLYLGSFLAAKNSEWLLEANVTKIVNVTSEVPSYFLSKKEKEndkiisekdeidsfivdddedenededdedidddddddddddddenedened
. |.|.....|.  .|.. ..| | ..| ||..|.... ..|  ..                                                      
pfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi....................................................

edgnqdenvdigdekdkemkdlpitpspnekkeeniemkdnddkdqemkdspaaaaatsstnekkeeenvemkdeltinnipikidqvnedvdsekikel
                                                                                                    
....................................................................................................

siKYLRISISDSFRSKIENYFQEAIDFINQGnvDGSEKSNVLIHCKQGRSRSPSIVIAYLMSnEKWTLEKAFNHVSSVSP
  .||.. . |.   ... .......||..     ... .||.||. | .|.. .|.||||   ...||.|...| .  |
..qylhlpwpDhgvpdlsqlllflllfiekl..aldkggpvlVHCsaGvgRtgtlvaaylml.lgvsleeavalvrekRp

0036282 (Phosphotyrosine protein) phosphatases II 203-482 1.6e-18 62.4 In-house 11-146 (174) alignment
Range on Protein: 203-482
Range on HMM: 11-146/174.0
KGVEIIPHLYLGSFLAAkNSEWLLEANVTKIVNVTSEVPSY-------FLSkkekendkiisekdeidsfivdddedenededdediddddddddddddd
....| |.|..|.. .| . |.| | ..| .|....|..         . .                                                 
dlsyitprliagqgpla.fwemlkelgittvvmlleekelglykcinywpe.................................................

enedenededgnqdenvdigdekdkemkdlpitpspnekkeeniemkdnddkdqemkdspaaaaatsstnekkeeenvemkdeltinnipikidqvnedv
                                                                                                    
....................................................................................................

DSEKIKELSIKYLRISISDSFRSKIENyFQEAIDFINQGNVDgSEKSNVLIHCKQGRSRSPSIVIAYLMSNEKW-TLEKAFNHVSSVS
..|  ..| |.||.. . |     ..  ..|...|...   . ...  ||.||. |..|.. .|.||||   .. .|..|...| .. 
lredlerlgiqylylpwpDhgvpdlsi.llefvkfveealse.dpggpvlVHCsaGvgRtGtlvaaylmlrglleslvdaldlvrelR

subfamily_Choan-DSP_MKP-1_pd Subfamily Choan-DSP_MKP-1 367-500 1.6e-18 60.6 In-house 20-144 (148) alignment
Range on Protein: 367-500
Range on HMM: 20-144/148.0
KKEEENVEMKDELTINNIPIKIDQVNEDVDSEkikelSIKYLRISISDSFRSKIENYFQEAIDFINQGNVDGSeksNVLIHCKQGRSRSPSIVIAYLMSN
|| . ..|.  .| . .|     . .  .|       .|.|| ....|  .  .  .|...|.|... . .|     ||.|.. |.|||  .....|.  
kksaadlealkalgvtrivnatkerdnaldqr.....gieYlhvaldDkpkedlsaiFediiafvrkakdeGr...rvLvhlqmGvsrssalallwlidf

EKWTLEKAFNHVSSVSPKnLTVNDGFKKKLMDLE
.. .|..|.. | |  .  .  | || |.| .||
krvslkealalvkskrry.vdpnlgfLkqLaele

subfamily_Dicty-DSP19-like_pd Subfamily Dicty-DSP19-like 371-502 1.8e-18 60.4 In-house 22-151 (154) alignment
Range on Protein: 371-502
Range on HMM: 22-151/154.0
ENVEMKDELTINNIPIKIDQVNEDVDSEKIKELSIKYLRISISDSFRSKIENYFQEAIDFINQgNVDGSEKSNVLIHCKQGRSRSPSIVIAYLMSNEKWT
 ....|.   | |. | |. .  | .|.    . |.||.. . |  . .| . .. | .||.. .. | |...||.|...| ||| ...|.||| . | .
ldlqlkniksilnvgiGinnlftdensdindgfiieylnlelfddvnfdiiekldkafefidd.aiggvennkvlvhsdkGvsrsaallisylmdklkis

LEKAFNHVSSVSPkNLTVNDGFKKKLMDLEME
| .|.  . .  .  .  | || |.|   | |
lslalellkdsry.iikPnqGflkqleifeke

subfamily_MKPLT_pd Subfamily MKPLT 402-505 3e-18 59.9 In-house 63-162 (164) alignment
Range on Protein: 402-505
Range on HMM: 63-162/164.0
ELSIKYLRISISDSFRSKIENYFQEAIDFINQGnVDGSekSNVLIHCKQGRSRSPSIVIAYLMSNEKWTLEKAFNHVSSVSpKNLTVNDGFKKKLMDLEM
  |..||.....|   ... .... | .|. .  .|.     ||.|| ||.||| |. .|.|.. ..|||..|....        . | || |.|   | 
pksveYlqvkvedesdeqlssfleraakflada.idsG..GrvlvhcvqGksrsssvtvafLikskgwtlkeayeylkerr.sivapnrGflkqlakfee

ELFG
 ..|
lilG

subfamily_MKPLV_pd Subfamily MKPLV 402-505 3e-18 59.9 In-house 63-162 (164) alignment
Range on Protein: 402-505
Range on HMM: 63-162/164.0
ELSIKYLRISISDSFRSKIENYFQEAIDFINQGnVDGSekSNVLIHCKQGRSRSPSIVIAYLMSNEKWTLEKAFNHVSSVSpKNLTVNDGFKKKLMDLEM
  |..||.....|   ... .... | .|. .  .|.     ||.|| ||.||| |. .|.|.. ..|||..|....        . | || |.|   | 
pksveYlqvkvedesdeqlssfleraakflada.idsG..GrvlvhcvqGksrsssvtvafLikskgwtlkeayeylkerr.sivapnrGflkqlakfee

ELFG
 ..|
lilG

PTEN_1 361-497 7.9e-18 60.0 In-house 45-185 (196) alignment
Range on Protein: 361-497
Range on HMM: 45-185/196.0
TSSTNEKKEEENVEMKDELTINNIPIKIDQVNED------VDSEKIKELSIKYLRISISDSFRSKIENYFQEAIDFINQGNVDGSeKSNVLIHCKQGRSR
  ..... ........|.|  ..|   ..  .|.       | |. ..  ..||...| |   . ..  | .. .||..   | . . .||.|||.|..|
deglyrgslkdvaadldnlkedgitlvvnlseeeelsgrsydleeffksgveylhfpieDhgapslselfdicksfiewllsdpn.gnvVlVHCkaGlgR

SPSIVIAYLMSNEKWTLEKAFNHVSSVSPKNLTVnDGFKKKLM
|  .|.||||. .|.| ..|. .| .  |..     .. ..|.
sGtvvaayLmykgkltadeAlelvrekRppgapn.spsqerll

subfamily_DSP15_pd Subfamily DSP15 390-501 1.2e-17 58.5 In-house 33-137 (151) alignment
Range on Protein: 390-501
Range on HMM: 33-137/151.0
QVNEdvDSEKI-KElsIKYLRISISDSFRSKIENYFQEAIDFINQGNVDGsekSNVLIHCKQGRSRSPSIVIAYLMSNEKWTLEKAFNHVSSVSPkNLTV
.|..  ...|. |.  |.|. |..||.   |....|.|...|| .  . .    |||.||  | |||  .|.||||.  .   ..|.. .          
svhd..nakkllkd..ieYkciaasDtpsaklskffkesvefihkcRlke...envlvhClaGvsRsvtlvvaYlmtvtelnwrdalevikaaRs.vanP

NDGFKKKLMDLEM
| |||..|.. |.
nfGfkrqlkeyek

subfamily_PTPMT1_pd Subfamily PTPMT1 397-483 2.4e-17 57.9 In-house 66-149 (171) alignment
Range on Protein: 397-483
Range on HMM: 66-149/171.0
SEKIKELSIKYLRISISDSFRSKIENYFQEAIDFINQGNvdgSEKSNVLIHCKQGRSRSPSIVIAYLMSNEKWTLEKAFNHVSSVSP
.|. |.| ...|.... | . .   .  .....||..     |... | .||| ||.|| ..|..||| .||...|.| ... .  .
teewkklgveqlqlatvDfteapdleklekgvefiekva...skgkrvYvHCkaGrgRsatlvacylmkkeklspeeAlkalkkkRk

subfamily_STYXL1_pd Subfamily STYXL1 394-505 8.2e-16 51.6 In-house 45-155 (157) alignment
Range on Protein: 394-505
Range on HMM: 45-155/157.0
DVDSEKIK----ElSIKYLRISISDSFRSKIENYFQEAIDFINQGNVdgsEKSNVLIHCKQGRSRSPSIVIAYLMSNEKWTLEKAFNHVSSVSpKNLTVN
  |..|.     .   | |.|...|. .... . ..||..||.. .    |.. ||.  ..| ||| ...||||| ..|.||.||....     .|.  |
smdadkliagvad.vakllhiavedeneadllerlkeavqfiekhkk...egevvlvfsnkGisrsaaviiaylmyskkitlkkaykylkkCk.envkPn

DGFKKKLMDLEMELFG
 .| ..| . | .|.|
rafveqlseWekqllg

0038934 (Phosphotyrosine protein) phosphatases II 395-485 4.7e-14 47.9 In-house 70-159 (194) alignment
Range on Protein: 395-485
Range on HMM: 70-159/194.0
VDSEKIKELSIKYLRISISDSFRSKIENYFQEAIDFINQGNvDGSEKSNVLIHCKQGRSRSPSIVIAYLMSNEKWTLEKAFNHVSSVSPKN
 | |..... |.||.. . | . .   .  .. .|.... . . ...  |..||| |..|.. .|.|||.   ....|.| ...... |. 
YdpeefekagieylklpfpddgtvPsleillrfldlvdefl.nedpggvvaVHCkaGlgRtGtlvaaYLiyrlgmsaeeAialfrekRpga

0045098 (Phosphotyrosine protein) phosphatases II 395-504 3e-13 45.3 In-house 149-272 (278) alignment
Range on Protein: 395-504
Range on HMM: 149-272/278.0
VDSEKIKELSIKYLRISISDSFRSKIENYFQEAIDFINQGNV-----------DGSEKSNVLIHCKQGRSRSPSIVIAYLMSNE---KWTLEKAFNHVSS
 | |. .   ..|| .   ..  . | ..|.|...||.. .              ...  ||.||. | .|.  .|.||||      ...|..|.... |
edlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvlVHCsaGvgRtGtlvaaylmlelleggvdlleavkelrs

VSPKNLTVNDGFKKKLMDLEMELF
  |     | .. . |.....||.
qRpglavqnleqyrflyefllell

0037934 (Phosphotyrosine protein) phosphatases II 392-504 6.6e-13 44.2 In-house 123-242 (243) alignment
Range on Protein: 392-504
Range on HMM: 123-242/243.0
NEDVDSEKIKELSIKYLRISISD----SFRSKIENYFQEAIDFINQ-----GNVDGsekSNVLIHCKQGRSRSPSIVIAYLMSNE-KWTLEKAFNHVSSV
 | .| .. . | |.|..... |    .  . . ....|...||..      . .|   . ||.||. |..|.  ...||||    ...||.|.... . 
lenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsg...gpvlVHCsaGvgRtGtliaaylmllllgvdleeavkllreq

SPKNLTVNDGFKKKLMDLEMELF
 |     . .. . |.....||.
Rpgkavqtpsqyrflyeallell

0051429 (Phosphotyrosine protein) phosphatases II 204-484 1e-12 43.8 In-house 16-206 (272) alignment
Range on Protein: 204-484
Range on HMM: 16-206/272.0
GVEIIPH-LYLGSFL---AAKNSEWLLEANVTKIVNVTSEV-------PSYFLskkekendkiisekdeidsfivdddedenededdedidddddddddd
| ...|. ||.....    |.. ..| | ... ||...||.       . |                                                 
grvvkpgrlyrsggplpltaadfwrlkelgiktivdLrseeErgrlkcdrywp...............................................

dddenedenededgnqdenvdigdekdkemkdlpitpspnekkeeniemkdnddkdqemkdspaaaaatsstnekkeeenvemkdeltinnipikidqvn
                                                                                                    
....................................................................................................

edvdsekikelSIKYLRISISDSFRSKIE---------------------------------------------------NYFQEAIDFINQgnvdgseK
            |.||...| |.    |.                                                   ... |.......       .
...........girylhlpilddsaptilygalrvtllseellldyilrellltlllsagearevmhlhytdwpdhgvpqeallellellld.......g

SNVLIHCKQGRSRSPSIVIAYLMSnEKWT--------------LEKAFNHVSSVSPK
 .||.||. |..|.  .| ..|.  . ..              ||.| ... .. |.
gpvlvHCsaGkdRTGtvvalllll.lgvsletivddYlltnlyleeaveelraqrpg

0042113 (Phosphotyrosine protein) phosphatases II 397-482 1.3e-12 43.2 In-house 133-222 (245) alignment
Range on Protein: 397-482
Range on HMM: 133-222/245.0
SEKIKELSIKYLRISISDSFRSKIENYFQEAIDFINQGNVDgSEKSNVLIHCKQGRSRSPSIVIAYLM-----SNEKWTLEKAFNHVSSVS
 .. .   | |..... |     . ........|...   . ...  ||.||. |..|.  ...||||     .. ...||.|. .. |  
gddesrevihyhylpwpdhgvpdllellldflefvrkalae.dsngpvlVHCsaGvgRtGtfiaaylmleqlekelgvsleeavkelrsqR

subfamily_Sponge-DSP-Subfam1_pd Subfamily Sponge-DSP-Subfam1 371-503 2e-12 40.4 In-house 15-141 (145) alignment
Range on Protein: 371-503
Range on HMM: 15-141/145.0
ENVEMKDELTINNIpIKIdQVNEDVDSEKIKELSIKYLRISISDSFRSKIENYFQEAIDFINQGNVDGsekSNVLIHCKQGRSRSPSIVIAYLMSNEKWT
..| . .|| |  | . .    . | |...|  ||. | |. .|     . ..|.|  |||..|  .|   . |..||  | ||| .. .|.||   . |
ndvptlqelgisri.vnm.aagslvasqelksesieillitaedlesydlsqhfdevtdfidkgkeeg...agvfvhcmagvsrsvtvsvaflmkycnmt

LEKAFNHVSSVSPKNlTVNDGFKKKLMDLEMEL
| .|   | |   .    |  | |.|..|| .|
lseaarqvrsnrlla.ypnvtflknllnlekql

0045450 (Phosphotyrosine protein) phosphatases II 400-502 1.8e-11 39.8 In-house 174-302 (307) alignment
Range on Protein: 400-502
Range on HMM: 174-302/307.0
IkELSIKYLRISISDS-----------------FRSKIENYFQEAIDFINQGNVDGS---EKSNVLIHCKQGRSRSPSIVIAYLMSNEK--------WTL
. . ....... ..|.                    ..  .|.|..|||.. .   .   ... ||.||. | .|......||||            ..|
h.ldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfeelldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdl

EKAFNHVSSVSpKNLTVNDGFKKKLMDLEME
..|.... .    .   | .. . |.....|
leavkllreqR.pgavqnpeqyrflyealle

0039614 (Phosphotyrosine protein) phosphatases II 398-502 1.9e-11 39.5 In-house 169-287 (297) alignment
Range on Protein: 398-502
Range on HMM: 169-287/297.0
EKIKELSIK----------YLRISISDSFRSKIENYFQEAIDFINQGNVDGSEKSNVLIHCKQGRSRSPSIVIAYLM-----SNEKWTLEKAFNHVSSVS
 .. .|...          .. ... |     . ....|....... .   ...  ||.||. | .|. ....||||     .. ......|.... .  
ytvrtlevtnngesrtvthfqytgwpdhgvppslellleflelvrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqR

pKNLTVNDGFKKKLMDLEME
  .   .... . |.|...|
.pgavqtpsqyrflydalle

0040439 (Phosphotyrosine protein) phosphatases II 401-504 2.1e-11 39.4 In-house 136-246 (249) alignment
Range on Protein: 401-504
Range on HMM: 136-246/249.0
KELSIKYLRISISDSFRSKIENYFQEAIDFINQGNVDGS---EKSNVLIHCKQGRSRSPSIVIAYLM-----SNEKWTLEKAFNHVSSVSPKnLTVNDGF
.  |...| | . |    ..  .|....|||.. .   .   ... ||.||. | .|.. ...||||      . ...|| |.... |  |.    |...
dgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdleeavkllrsqRpg.avqnpeq

KKKLMDLEMELF
 . |.....||.
yrflyeallell

subfamily_STYX_pd Subfamily STYX 404-501 1.3e-10 34.6 In-house 62-155 (166) alignment
Range on Protein: 404-501
Range on HMM: 62-155/166.0
SIKYLRISISDSFRSKIENYFQEAIDFINQGNVDGsekSNVLIHCKQGRSRSPSIVIAYLMSNEKWTLEKAFNHVSSVSpKNLTVNDGFKKKLMDLEM
...|| . ..|.   .|  |. .  .||..    |    .||.| . | ||| ..||||.|        .|| .|       ...|.|| ..|.. |.
rfrylvldvadntveniirylptvkefiddslqkg...gkvlvhgnagisrsaalviayimetyglkyreafayvqerr.fcinpnegfvsqlkeyea

subfamily_LRR-DSP_pd Subfamily LRR-DSP 404-507 3.8e-10 33.3 In-house 163-262 (263) alignment
Range on Protein: 404-507
Range on HMM: 163-262/263.0
SIKYLRI-SISDSFRSKIENYFQEAIDFINQGNvdgsEKSNVLIHCKQGRSRSPSIVIAYLMSNEKWTLEKAFNHVSSVSPKnLTVNDGFKKKLMDLEME
  ||| |  | |  . .| ..|.|   ||..|     .|  ||.||. | ||| ..||.||| ... ....|.. | .  |. .  | |||..|.  | .
lfkylsiddiedvdeadisqhfeetnafieeGr....kkGGvlvhcraGvsrsstlvisylmkkqrlkfkealdlvikkrpr.iqPnpGfkdqlkkyekk

LFGSN
|| .|
lfctn

0040438 (Phosphotyrosine protein) phosphatases II 402-483 5.2e-10 34.6 In-house 153-256 (317) alignment
Range on Protein: 402-483
Range on HMM: 153-256/317.0
ELSIKYLRISISDS----------------FRSKIENYFQEAIDFINQGNVDGSE-KSNVLIHCKQGRSRSPSIVIAYLM-----SNEKWTLEKAFNHVS
. .|..... ..|.                   ..  .... .||... .   .. .. ||.||. | .|. ....||||      ......|.|.... 
lagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavrealedpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelr

SVSP
.  |
eqRp

subfamily_MSG5_pd Subfamily MSG5 391-503 6.2e-10 32.4 In-house 54-160 (165) alignment
Range on Protein: 391-503
Range on HMM: 54-160/165.0
VNEDVDSEKIKELSIKYLRISIsdSFRSKIENYFQEAIDFINQGNvdgSEKSNVLIHCKQGRSRSPSIVIAYLMSNEKWTLEKAFNHVSSVSpKNLTVND
| ....  ...  ..||  |       |||   . .    |   .   |..  .|.||. | ||| |...||.|   . .|..|.... ||. .... . 
vakeindlellvpavkyyhiew..ehdskivkdlsrltriihaat...skrkkilvhcqcglsrsaslivayimkyynlslrdaydklksva.ddispsi

GFKKKLMDLEMEL
|.  .||. |. |
glifqlmeweval

subfamily_DSP6_pd Subfamily DSP6 197-254 6.6e-10 32.7 In-house 7-64 (158) alignment
Range on Protein: 197-254
Range on HMM: 7-64/158.0
MQEKTTKGVEIIPHLYLGSFLAAKNSEWLLEANVTKIVNVTSEVPSYFLSKKEKENDK
 .....  |||.|.|||||  .|.|.| | . .. ...||||..|. | ...| .  .
kkaeaefpveilpllylGsakdasnlevlkklkikyvlnvtsnlpnkfeesgelkylq

0036941 (Phosphotyrosine protein) phosphatases II 418-480 4.7e-09 31.4 In-house 181-254 (297) alignment
Range on Protein: 418-480
Range on HMM: 181-254/297.0
SKIENYFQEAIDFINQGNVDGS---EKSNVLIHCKQGRSRSPSIVIAYLM--------SNEKWTLEKAFNHVSS
 .. ..... .|||.. .   .   ... ||.||. | .|| ....|.||         ...... .|.... .
hgvpespaslldfielvrkvlkllpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklRe

0043336 (Phosphotyrosine protein) phosphatases II 407-483 1.2e-08 30.3 In-house 180-257 (278) alignment
Range on Protein: 407-483
Range on HMM: 180-257/278.0
YLRISiSDSFRSKIENYFQEAIDFINQGNvdgSEKSNVLIHCKQGRSRSPSIVIAYLM-----SNEKWTLEKAFNHVSSVSP
|| .   ... . .. ...   ..... .   .... ||.||. | .|.  ....||.     .. ...||.|.... .  |
ylgwp.dhgvpeslsllldflkavreale...dsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRp

0047943 (Phosphotyrosine protein) phosphatases II 420-480 8.5e-08 27.4 In-house 184-249 (273) alignment
Range on Protein: 420-480
Range on HMM: 184-249/273.0
IENYFQEAIDFINQGNVDGSEKSNVLIHCKQGRSRSPSIVIAYLM-----SNEKWTLEKAFNHVSS
  ... | |..... .    ... |..||. | .|. ......|.      . ......|.... |
slesllefielvrkalealpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrs

subfamily_Slingshot_pd Subfamily Slingshot 198-257 9.7e-08 25.6 In-house 13-72 (169) alignment
Range on Protein: 198-257
Range on HMM: 13-72/169.0
QEKTTKGVEIIPHLYLGSFLAAKNSEWLLEANVTKIVNVTSEVPSYFLSKKEKENDKIIS
  .  .  .|  |.||||   | | | | | .|. |.||| |. ..|  | |  | ..  
lgqldsaskifdhvylGsewnasnleelkengveyilnvtkeidnffpekfeylnirvyd

subfamily_DSP10_pd Subfamily DSP10 199-246 1.3e-07 25.6 In-house 9-56 (159) alignment
Range on Protein: 199-246
Range on HMM: 9-56/159.0
EKTTKGVEIIPHLYLGSFLAAKNSEWLLEANVTKIVNVTSEVPSYFLS
 .|.. ....|.|.|||   |.. . | . |.| ..|||..|| .|  
ietapasqvlpfLflGsekdaadldaldrlnitavlnvttsvPnefee

PTPlike_phytase Inositol hexakisphosphate 319-464 1.4e-07 26.2 Pfam-A 22-147 (149) alignment
Range on Protein: 319-464
Range on HMM: 22-147/149.0
DKEMKDLPITPSPNEKKEENIEMKDNDDKDQEMKDSPAAAAATSSTNEKKEEENVEMKDeltinnipikidqvnEDVDSEKIKELSIKYLRISISDSFRS
..|.. |  ... .... |..| . ..|  .|..    .      |.|..... .|..                | .. |. .. ..|| || |.|  . 
edelenlkeysgieaeeledlekrlkedvlkeaeeyegrilvhreteegvqktltevte...............evyeeelaegfgvkYvRipitdeqap

KiENYFQEAIDFINQGnVDgseKSNVLIHCKQGRSRSPSIVIAYLM
. |... . ...|..   .   .. ....|..|| |.   .. . .
e.eedvDafvrliksl.pr...dtalvfnCqaGrgRTTtamviadL

PTPlike_phytase Inositol hexakisphosphate 319-464 1.4e-07 26.2 In-house 22-147 (149) alignment
Range on Protein: 319-464
Range on HMM: 22-147/149.0
DKEMKDLPITPSPNEKKEENIEMKDNDDKDQEMKDSPAAAAATSSTNEKKEEENVEMKDeltinnipikidqvnEDVDSEKIKELSIKYLRISISDSFRS
..|.. |  ... .... |..| . ..|  .|..    .      |.|..... .|..                | .. |. .. ..|| || |.|  . 
edelenlkeysgieaeeledlekrlkedvlkeaeeyegrilvhreteegvqktltevte...............evyeeelaegfgvkYvRipitdeqap

KiENYFQEAIDFINQGnVDgseKSNVLIHCKQGRSRSPSIVIAYLM
. |... . ...|..   .   .. ....|..|| |.   .. . .
e.eedvDafvrliksl.pr...dtalvfnCqaGrgRTTtamviadL

subfamily_RNGTT_pd Subfamily RNGTT 390-486 1.6e-07 25.2 In-house 63-158 (189) alignment
Range on Protein: 390-486
Range on HMM: 63-158/189.0
QVNEDVDSEKIKELSIKYLRISISDSFRSKIENYFQEAIDFINQGNVdGSEKSNVLIHCKQGRSRSPSIVIAYLMSNEKWTLEKAFNHVSSVSPKNL
. .   | |....  ||| ....     .  ..  .| |  ... .   . .. . .||. |  |.  ....||. .|.| .|.| .  ..  |. .
ntsryYdkeelekegikyvklqcagkgeaPeaeqvkefiklveeffk.knpeevigvhCthGfnRtGFlivsyLvekedwsveaavalFakaRppGi

subfamily_DSP1_pd Subfamily DSP1 200-245 1.7e-07 25.5 In-house 13-59 (163) alignment
Range on Protein: 200-245
Range on HMM: 13-59/163.0
KTTKGVE-IIPHLYLGSFLAAKNSEWLLEANVTKIVNVTSEVPSYFL
|.   || |...|||||   | | | | . ..|.|.||..|.. .| 
klydPvekildfLylGsetvasnleiLkslgitailnvskeldnvfe

subfamily_DSP19_pd Subfamily DSP19 203-255 6.9e-07 23.7 In-house 11-63 (152) alignment
Range on Protein: 203-255
Range on HMM: 11-63/152.0
KGVEIIPHLYLGSFLAAKNSEWLLEANVTKIVNVTSEVPSYFLSKKEKENDKI
. .|..|.|||||  .|...| | | ..| |.||. .||  | .. .  . .|
evgeveprlylgsqdvaadkeilkekkitHilnvatgvpnvfpkdftylsiei

0051299 (Phosphotyrosine protein) phosphatases II 422-480 1.6e-06 23.3 In-house 202-263 (288) alignment
Range on Protein: 422-480
Range on HMM: 202-263/288.0
NYFQEAIDFINQGNVdgSEKSNVLIHCKQGRSRSPSIVIAYLM-----SNEKWTLEKAFNHVSS
. . . . .... .   | .. |..||. | .|.  .....|.      ........|.... .
ellldflrlvrkala..sgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlre

Daxx Daxx Family 263-399 2.4e-06 15.3 Pfam-A 430-580 (713) alignment
Range on Protein: 263-399
Range on HMM: 430-580/713.0
DSFIV--DDDEDENEDEDDEDIDDDDDDDDDddddeNEDENEDEDGNQDENVDIGDEKDKEMKDLPITPSPNEKKEENIE----------M------KDN
.|  .  .. |.|.. |..|| .||.....|     ...|.|.|. ...|...  .|......  .   . .|..||. |          .      . .
esPllasqeseeeekaekeedeeddekeeed.....kseeeeeeeeeeeeeeeadneeeedleassegegddeeeeedeekndevakgirvseeqqkres

DDKDQEMKDSPAAAAATSSTNEKKEEENVEMKDELTIN-NIPIKIDQVNEDVDSEK
. .... |..| .  |. ...|..|...  ...|  ..  ..... .  |. |  .
svqpespkeepqepeavdaekegeesdeellaeeeplsshtelesvatveerdiss

SSP160 Special lobe-specific silk protein SSP160 74-106 3.5e-06 13.5 Pfam-A 300-332 (756) alignment
Range on Protein: 74-106
Range on HMM: 300-332/756.0
TNNTTTSSTTTTTTTTNNNESTKTGLAAIITPV
|  ||| |||.| .|.  | || .|   | . .
tsttttnsttstnstsssnsstiagsidiaanl

0046845 (Phosphotyrosine protein) phosphatases II 422-479 4.5e-06 21.7 In-house 185-250 (284) alignment
Range on Protein: 422-479
Range on HMM: 185-250/284.0
NYFQEAIDFINQGNVDGSEKSNVLIHCKQGRSRSPSIVIAYLMSNE--------KWTLEKAFNHVS
. ..| ...... . . . .. ...||. | .|.  .....|. .         ......|.... 
edlleflrlvrellenlpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlr

subfamily_DSP15_pd Subfamily DSP15 206-244 6.4e-06 20.3 In-house 4-37 (151) alignment
Range on Protein: 206-244
Range on HMM: 4-37/151.0
EIIPHLYLGSFLAAKNSEWLLEANVTKIVNVTSevpsyF
...| |||| |  .|..| | | |.|.|..|        
kvlpglylgnfrdskdeelLkeknithilsvhd.....n

0050432 (Phosphotyrosine protein) phosphatases II 423-478 7.8e-06 20.9 In-house 218-274 (308) alignment
Range on Protein: 423-478
Range on HMM: 218-274/308.0
YFQEAIDFINQGNvdgsEKSNVLIHCKQGRSRSPSIVIAYLM-----SNEKWTLEKAFNHV
 . . ...... .    .......||. | .|.  .....|.      . ......|....
illdflelvrksl....pggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkkl