Gene DDB_G0269272 in Dictyostelium discoideum

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family Myotubularin
Subfamily Ank-MTMR1
Protein sequence
ID Type Fasta BLAST phosphatome Note
DdisP022_AA protein Get Run
DdisP022_AA_714-1108 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_Ank-MTMR1_pd Subfamily Ank-MTMR1 701-1105 2.3e-287 944.1 In-house 1-405 (405) alignment 
Range on Protein: 701-1105
Range on HMM: 1-405/405.0
NNQNNQNNNNNFINGWEIYNQKKEYLRFNINIDENNNSNCYWRVTSINKEYKMCSSYSSSLVVLSKTLDKDLEKIFSFRSKGRIPSLSWKDPNSNASISR
..|||.|.....|.|||.||||||||||||.|||.|.|||||.|||||||||||||||||||||||.|||||||||||||||||||||||||.|||||||
stqnnlnsstssidgwevynqkkeylrfniyideenssncywkvtsinkeykmcssyssslvvlskaldkdlekifsfrskgripslswkdpssnasisr

CSQPLVGIERSRCPEDELYCSNLALSAPSKTLYLIDARPKLNAYANTANGAGFENIHNYPNCKLVFMNIPNIHVIRKSLEKLTSSMRSSTRDKDHTESTD
||||||||||.||||||||||.|||||||||||||||||||||.||||||||||||||||||||||||||||||||||||||...|.||.||||||||||
csqplvgierarcpedelycsslalsapsktlylidarpklnaiantangagfenihnypncklvfmnipnihvirksleklvlamkssardkdhtestd

MRWWGCIEETGWISHIKSILEAATFSADLILKGNSILVHCSDGWDRTPQITSLTQILLDPYYRTIVGFQVLIEKEWLSFGHKFSLRLGHLPGNEEERSPI
||.||.|||||||||||||||||||||.||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
mrfwgyieetgwishiksileaatfsaelilkgnsilvhcsdgwdrtpqitsltqilldpyyrtivgfqvliekewlsfghkfslrlghlpgneeerspi

FQQFLDCCFQLCSQFPLLFEFTPTLLLFISDNIHSCKYGTFLNNCEKDRVQDQVKFKTTSIWSEVHFNIHKFLNPYYNPQDIQSIKPKLYSRCLELWKAC
|||||||||||.|||||||||||.|||||||||||||||||||||||||||||||.||.||||||..|..||||||||||||||||||||||||||||||
fqqfldccfqllsqfpllfeftpslllfisdnihsckygtflnncekdrvqdqvktktisiwsevnlnvnkflnpyynpqdiqsikpklysrclelwkac

YMRVE
|||||
ymrve
subfamily_MTMR1_pd Subfamily MTMR1 713-1105 2.5e-136 447.0 In-house 4-387 (389) alignment 
Range on Protein: 713-1105
Range on HMM: 4-387/389.0
INGWEIYNQKKEYLRFNINIDEnnnsncYWRVTSINKEYKMCSSYSSSLVVLSKTLDKDLEKIFSFRSKGRIPSLSWKDPNSNASISRCSQPLVGIERSR
 .||..|. ..|. |  .  ..       ||.|..||.|..| .|.. |||.. . |.||.|. .||||||.|.||| .....|.|.|.||||||.. .|
edGWkvydpeaelerlgllnek......lWritklnkkyelcdtYpavlvvpkvvsdedlkkvaafrskgRlPvlswlnkenqavilrasqplvGlsgkr

CPEDELYCSNLALSA-PSKTLYLIDARPKLNAYANTANGAGFENIHNYPNCKLVFMNIPNIHVIRKSLEKLTSSMRSSTRDKdhtestdmRWWGCIEETG
..||| | ...  .   |. |...|||.. || || |.| | |. ..| |..|.|..|.||||.|.||.||   . ... ||        .|   .|.| 
skedekylqaileanaqsekllildarssvnavankakgkgyeseeaYknaelifldihnihvvReslkklkelvlpnvddk........kwlsalestk

WISHIKSILEAATFSADLIL-KGNSILVHCSDGWDRTPQITSLTQILLDPYYRTIVGFQVLIEKEWLSFGHKFSLRLGH--LPGNEEERSPIFQQFLDCC
|..|||.||..|.  .. .  . .|.||||||||||| |.|||...|||.||||| ||.||||||||||||||. ||||   . ...||||.| ||.|| 
WlehiklilagavkivekvetektsvlvhcsdGWDRtaqltsLamlllDsyyRtieGfevliekeWlsfGHkfkeRlghgdknssdaersPvFlqfiDcv

FQLCSQFPLLFEFTPTLLLFISDNIHSCKYGTFLNNCEKDRVQDQVKFKTTSIWSEVHFNIHKFLNPYYNPQ-DIQSIKPKLYSRCLELWKACYMRVE
.||  |||  |||. ..|... |...|| .|||| |.|| ||...|| ||.|.|| |. . ..| ||.|... . . . ||.. |.|||||  |.| .
wqltrqfptAFefneefLitlldhlysclfGtflfnsekervkekvkektvslwsyvnsskeeftnplyaeelekkvlypkaslrrlelWkeyylrwn
subfamily_Dicty-MTMR1-like_pd Subfamily Dicty-MTMR1-like 705-1104 1.8e-132 434.3 In-house 5-402 (404) alignment 
Range on Protein: 705-1104
Range on HMM: 5-402/404.0
NQNNNNNFINGWEIYNQKKEYLRFNINIDEnnnsncYWRVTSINKEYKMCSSYSSSLVVLSKTLDKDLEKIFSFRSKGRIPSLSWKDPNSNASISRCSQP
....  .  .|| ||....|| | .|. .        ||...||..|..|..| . ||| ..  |..|.|..||||||||| |||. ...|..|.|.|||
ysekksvledgwliydaeeEykRlgikses......eWriskinsdyelcetYPkllvvPesisDeelkkvasfRskgRiPvlswrhrsknstitRssqp

LVGIERSRCPEDELYCSNLALSAP-SKTLYLIDARPKLNAYANTANGAGFENIHNYPNCKLVFMNIPNIHVIRKSLEKLTSSMRSSTRDkdhtestDMRW
|||...||. |||..   . .... ..|||..|||||.|| ||.|.|||.|.|..| ||.. |.|| ||| .|.||.||. ...|....       .  |
lvGltksrseedEklinsirkaktqletlyildarpkanavansakgagyedisryenceieflnienihelreslkklkkavnsiiek.......eknw

WGCIEETGWISHIKSILEAATFSADLIL-KGNSILVHCSDGWDRTPQITSLTQILLDPYYRTIVGFQVLIEKEWLSFGHKFSLRLGH-LPGNEEERSPIF
.  .|...|. |||..||...  ..||  ...|.|||||||||||.|..||.|.||||||||| ||.||||||||||||||  | |.    ...||||||
lselessrWldhiklllegskriveliekekssvlvhcsdgwDrtsqlsslsqllldpyyrtiegFivliekewlsfGhkfaqRigqttekssdersPif

QQFLDCCFQLCSQFPLLFEFTPTLLLFISDNIHSCKYGTFLNNCEKDRVQDQVKFKTTSIWSEVHFNIHKFLNPYYNPQDIQSIKPKLY--------SRC
 ||.||..||  |||  |||   .|. | |.. ||..|||| ..||.|.|......|.|.|.... | ...|||.|  .. .. . .           . 
lqFidcvyqltkqfptsFeFnekflikildalyscrfgtFLydsekeRqqnnlaketvslWalleankseylnplyilekkeqkenitssessssadikl

LELWKACYMRV
..||.  |.| 
iklWseyylrw
subfamily_MTMR6_pd Subfamily MTMR6 704-1105 1.1e-127 418.7 In-house 7-396 (397) alignment 
Range on Protein: 704-1105
Range on HMM: 7-396/397.0
NNQNNNNNFINGWEIYNQKKEYLRFNInidennnSNCYWRVTSINKEYKMCSSYSSSLVVLSKTLDKDLEKIFSFRSKGRIPSLSWKDPNSNASISRCSQ
........  .||. .. |.|| |  .       .| .| .|..||.|..|..|...|.| ...  . |     ||||||.| ||.   . .|.| ||||
kpkkdkeekvsGwklldlkaeytrmgv.......pnekwtltdlnkdyelcdtyprelyvPksatkevlvgsskfrskgrlPvlsylhkeneaaicrcsq

PLVGIERsRCPEDELYCSNLALSAP-SKTLYLIDARPKLNAYANTANGAGFENIHNYPNCKLVFMNIPNIHVIRKSLEKLTSSMRSSTRDKDhtestdmR
|| |... || |||     .  . | |..||..|.|||||| || |.| |.|| .|| |.|. |..| ||||.|.||.||   .. .....         
plsgfsa.rcledeklleairkanpnsellyvvdtrpklnalankaagkGyenednysnikfqfvgienihvmreslqkllevvelksksvs.......e

WWGCIEETGWISHIKSILEAATFSADLI-LKGNSILVHCSDGWDRTPQITSLTQILLDPYYRTIVGFQVLIEKEWLSFGHKFSLRLGHLPGNEEERSPIF
.. ..|..||. |||..|.|..| |  .  .| |.||||||||||| |..||...||||||||| ||.||||||||||||||| | |.| ... | ||||
flsglessgwlkhikavldasifiakavaeegasvlvhcsdGwdrtaqvcslasllldpyyrtikGflvliekewlsfGhkfsercGlldedskevsPif

QQFLDCCFQLCSQFPLLFEFTPTLLLFISDNIHSCKYGTFLNNCEKDRVQDQVKFKTTSIWSEVHFNIHKFLNPYYNPQDI-QSIKPKLYSRCLELWKAC
.|||.| .||..|||  |||  . || . | ..||..|||| |||||| . ..| .|.|.|. .. . ...|||.|...   . .||.. . .|.||.| 
tqflecvwqlleqfpkafefnerfllelhdhvyscqfGtflgncekdrrdlklkertkslwayllerkddylnplykaetekevlkpdtapaalklwral

YMRVE
|.| .
ynrfd
0040695 (Phosphotyrosine protein) phosphatases II 712-1104 1e-125 413.3 In-house 4-385 (388) alignment 
Range on Protein: 712-1104
Range on HMM: 4-385/388.0
FINGWEIYNQKKEYLRFNINIDennnsncYWRVTSINKEYKMCSSYSSSLVVLSKTLDKDLEKIFSFRSKGRIPSLSWKDPNSNASISRCSQPLVGIERS
 ..|| .|. ..|. | ....|       .||....|..|..|.|| . ||| .   |..|.....|||||||| ||.. ||..|.. |.||||||.  |
leegwslydilrelkrlglgld.......lwrisivNenyelcpsYPallvVPksisdellkrvarfrskgriPvlsyrhpnngavllRssqplvgllls

RCPEDELYCSNLA-LSAPSKTLYLIDARPKLNAYANTANGAGFENIHNYPNCKLVFMNIPNIHVIRKSLEKLTSSMrsstrdkdH-----TestdmRWWG
|. ||| ... .  |  ....|...|.||||||.||.| | |.||...|||..|.|.|||||||.|.|| ||.. .              .     ... 
rsledeklleailkllpnlskllivdlrpklnalanralgggvenedaypnaeliflnipnihvvreslqklldac........lnvpdsl.....nlls

CIEETGWISHIKSILEAATFSADLILKGNS-ILVHCSDGWDRTPQITSLTQILLDPYYRTIVGFQVLIEKEWLSFGHKFSLRLGHLPG--NEEERSPIFQ
 .||.||...||.|||.| . ..|. .||| .|||||||||||.|..||.|.||||||||. |||||||||||||||||. |||||..  . .|.||.| 
lleesgwldliklilelavlivklldlgnssvlvhcsdgwdrtsqlssLaqllldPyYRTleGFqvLiekeWlsfghkfadRlghleseidskefsPvFl

QFLDCCFQLCSQFPLLFEFTPTLLLFISDNIHSCKYGTFLNNCEKDRVQDQVKFKTTSIWSEVHFNIHKFLNPYYNPQDIQSIKPKLYSRCLELWKACYM
.|||| .||  |||. |||...||||. | ..|| .|||| |.||.|.. .|  .| |.|| .  .  .||||.|.|   . ..| |  ..| ||  .|.
lFLdcvwqLlrqfPtaFeFnerlLlfLadhlyscrfgtFlfnsekerlelsvsertlslwsyllsrkseflnplYdpsslevllpslsvldlllWleyyl

RV
|.
rw
Myotub-related Myotubularin-like phosphatase domain 700-1051 4.9e-120 393.5 Pfam-A 7-352 (353) alignment
Myotub-related Myotubularin-like phosphatase domain 700-1051 4.9e-120 393.5 In-house 7-352 (353) alignment
subfamily_MTMR3_pd Subfamily MTMR3 827-1102 9e-90 294.5 In-house 170-440 (442) alignment 
Range on Protein: 827-1102
Range on HMM: 170-440/442.0
APSKTLYLIDARPKLNAYANTANGAGFENIHNYPNCKLVFMNIPNIHVIRKSLEKLTSSMRsSTRDkdhtestDMRWWGCIEETGWISHIKSILEAATFS
  .|.| ..|||    |.|| | | |.|.   ||||..||....||| .|||...| . .  .. |       ...|.. .|.| |. ..  .|.||   
eekkkllivdarsytaafanrakgGGceleeyypncevvflglanihavrksfnslralls.qspd.......esnwlsalektkWlqnlsvllkaavkv

ADLILK-GNSILVHCSDGWDRTPQITSLTQILLDPYYRTIVGFQVLIEKEWLSFGHKFSLRLGHLPGNE--EERSPIFQQFLDCCFQLCSQFPLLFEFTP
.. . | | ..|||||||||||.||..|...||||||||. ||.||.|.|||.|||||. | || .  .  .||.|.| |.||.  ||  ||| .|||. 
veavdkegrpvlvhCsdGWdrttqivalakllldpyyrtleGfkvlvereWldfGhkfadrcghgenvddanercPvflqwldavhqlqrqfPtsfefne

TLLLFISDNIHSCKYGTFLNNCEKDRVQDQVKFKTTSIWSEVHFNIHKFLNPYYNPQDIQSIKPKLYSRCLELWKACYM
. |. .    .|| .|||| |.||.| ...|| .| |.|| .. . ... |  |.... . . |.   | |.||.. |.
aflvklvqhtysclfGtflansekereeekvkertlsvWsllrakekeyrnllykekteavllpavsvrelklwsevyl
subfamily_MTMR9_pd Subfamily MTMR9 714-1104 1.2e-89 293.1 In-house 13-392 (393) alignment 
Range on Protein: 714-1104
Range on HMM: 13-392/393.0
NGWEIYNQKKEYLRFNInidennnSNCYWRVTSINKEYKMCSSYSSSLVVLSKTLDKDLEKIFSFRSKGRIPSLSWKDPNSNASISRCSQPLVGIERSRC
.|.. .....|. .          . . ||..|.||..|.|.|| .|..|  .  |..|... .||..||.| ||. . . .| . |.||||.| .  ||
dgysafdrenefaklis.......asdewRissvNknfkvcasypesvivPkaiddeelkasaafreggrfPvLsylhketkavllrssqplcgssgkrc

PEDELYCsNLALSAPsKTLYLIDARPKLNAYANTANGAGFENIHNYPNCKLVFMNIPNIHVIRKSLEKLTSSMRSSTRDKDhtestdmRWWGCIEETGWI
 |||    ||.|..  |  . .| | |  | .. ..|.|.|  ..|.. | .  .. ....| .|| ||  ..   . ..|       ...  .|..||.
kedekll.nlvlkkl.kkGlivdtrsksaaenarskgggietevkysqwkkasrslesvasiqdslaklleacsdaglstd.......kflsrleksgwl

SHIKSILEAATFSADLILK-GNSILVHCSDGWDRTPQITSLTQILLDPYYRTIVGFQVLIEKEWLSFGHKFSLRLGHLPGNE---EERSPIFQQFLDCCF
|... .||||.  |... . |....|| ..| | | |.|||.|..|||..||. ||. |||.||.  || |. |  ..  .|   ....|.|  |||| .
sqvadlleaalvvaqcldeegapvvvhgeeGlDatlqvtsLaqlildpdaRtvrgfealiereWiqaGHPFasRaskvaaketkkklsgpvfllFLDcvy

QLCSQFPLLFEFTPTLLLFISDNIHSCKYGTFLNNCEKDRVQDQVKFKTTSIWSEVH--FNIHKFLNPYYNPqDIQSIKPKLYSRCLELWKACYMRV
|. ||||. |||  .|| ..  . .|...|||| ..|. | . ..| ||.|.|| |.   ....|||| |.. . . | |     .||||.  |.| 
qilsqfpasFEFneelLillfehsyssqfgtflcdneaerkelklkkktvslwsyvnrpeklkqflnplyea.naeviwpsvapqslelWselylrw
subfamily_MTMR5_pd Subfamily MTMR5 855-1098 7.1e-56 182.0 In-house 221-476 (483) alignment 
Range on Protein: 855-1098
Range on HMM: 221-476/483.0
NIHNYPNCKLVFMNIPNIHVIRKSLEKLTSSMRSSTRdkdHTESTDMRWWGCIEETGWISHIKSILEAATFSADLIL-KGNSILVHCSDGWDRTPQITSL
... . .. .. .....|  ...|..||     .||.    .|..   .   .|.  |.. |.|.|. ..  .||.  .| |.||   |||| | |..||
ksevdskaefipvelveirqvkasfkkllraClpsta...veeaesqsFlksvedseWlqqissllqlsgavvdlldlqgssvlvslEdGwdvtaqvssl

TQILLDPYYRTIVGFQVLIEKEWLSFGHKFSLRLGHLPGNEE-ERSPIFQQFLDCCFQLCSQFPLLFEFTPTLLLFISDNIHSCKYGTFLNNCEKDRVQD
.|.||||||||. ||.||.|||||.|||.|. |  . . ...   .|.| ||||| .|. .|||| |||    | |..    |... ||| ..|..|.. 
aqllldpyYRtleGFkvLveKEWLafGHrFtkrsnqtlsaqssgfaPvFlqFLDcvhqvsrqfPlafefndfylkflayhsvsnrfrtfllDseyerles

QV----------KFKTTSIWSEVHFN---IHKFLNPYYNPQDIQSIKPKLYSRCLELWK
..          |  ..|.|  .. .      | |  |.|.. . ..|.     |..|.
gllyeekaekrakkagksvwdyidrqhkrspifynflyspdesevlrPssnvsslkvWd
subfamily_MTMR10_pd Subfamily MTMR10 730-1100 9.7e-47 151.5 In-house 14-311 (380) alignment 
Range on Protein: 730-1100
Range on HMM: 14-311/380.0
INIDENNNSNCYWRVTSINKEYKMCSSYSSSLVVLSKTLDKDLEKIFSFRSKGRIPSLSWKDPNSNASIsRCSQplVGIERSRCPEDELYCSNLALSAPS
..  |...... ..|.  |.  . . ..   .||. .  |.|.|...    ..| | ..|. ....| . |.|.   .   |  .|.|     |. .. .
leekekktvsdaivvllknelfaaaqtlPqyfvvpnslsdsdverlsrhykesRfplwvwshakgaall.rlsa..lqeaesadkekeekmlelvrkchp

KTlylidarpklnayantangagfenihnypNCKL--VFMNIPNIHVIRKSLEKLTSSMRSSTRDKdhTESTDMRWWGCIEETGWISHIKSILEAATFSA
                               . ||  .  ..|.|. . |. .|| .    .|  .    ..| .| . .|.|.|.  .. .|. |.  .
an.............................dvklvdlsdelpsiqdvqkaylklreLcvidtsee..fvtlddkwlssLektrWLayvrlclstasdav

DLI-LKGNSILVHCSDGWDRTPQITSLTQILLDPYYRTIVGFQVLIEKEWLSFGHKFSLRLGHLPGNEEERSPIFQQFLDCCFQLCSQFPLLFEFTPTLL
...  |..|...  |.| |    . ||.|..|||.|||| ||| ||.||| . ||.|  ||||.  .|...||.|  ||||  ||  |||  ||||.|.|
ktvvekkrsvilqesegrDlscvvaSLaqlmldphyrtisGfqsliqkewvaaghpfldrlghikpseksespvfllFldcvdqlleqfpseFeFtetfL

LFISDNIHSCKYGTFLNNCEKDRVQDQVKFKttsiwsevhfnihkflnpyynpqdiqsikpklysrclelwkaC
. . |  ||. ..||| |.|. |..  |. .                                          .
ialwdsshsgifltflfnseeqrlkavvsss..........................................p
subfamily_pats1_pd Subfamily pats1 861-989 2.2e-25 81.1 In-house 335-459 (691) alignment 
Range on Protein: 861-989
Range on HMM: 335-459/691.0
NCKLVFMNIPNIHVIRKSLEKLTSSMRSStrdkDhtesTDMRWWGCIEETGWISHIKSILEAATFSADLILKGNSILVH-CSDGWDRTPQI---TSLTQI
 ....|...|  . ...   .|  |. |     |      .  |  |||  |.  .| .||||   . |. .|.|.|..  .|. . . ..   .||.|.
ssniiflslPtrekveerffdllqsilsl....d....gsddewkeieeskwvdsvkllleaavkvsnlldeGssvllknsidsPlieldlasisslaqv

LLDPYYRTIVGFQVLIEKEWLSFGHKFSLRLGH
|.||.|||. ||.|||||||||.|. || .  |
lsdPfyrtldGfkvliekewlsyGfPfskinyh
subfamily_MTMR3_pd Subfamily MTMR3 716-824 1.2e-22 73.3 In-house 17-126 (442) alignment 
Range on Protein: 716-824
Range on HMM: 17-126/442.0
WEIYNQKKEYLRFNINIDENN-NSNCYWRVTSINKEYKMCSSYSSSLVVLSKTLDKDLEKIFSFRSKGRIPSLSWKDPNSNASISRCSQPLVGIERSRCP
. . ....   .......    . .  ||....|...|.|||| . |.| ..  |.||.|  |||| .|.|.. |.  .. | . ||||| ||.   |. 
fllraasvaeeklkeeverlGfdlkeawrisdvnsdfklCssyPkklivPksitdddlkkvasfrslkrlPavvwrhkkngavlarcsqPevgwlgWrna

EDELYCSNLA
|||   ...|
edekllkaia
Ank_2 Ankyrin repeats (3 copies) 45-149 9.3e-19 55.7 Pfam-A 1-89 (89) alignment 
Range on Protein: 45-149
Range on HMM: 1-89/89.0
LHLIAMNDNMVALKFYLKKKyvvfK---GtnivvdqrdkdGYTPLHCAVNQGSFEIAKKFLSRGSDPNARTESGSTPLHLLSKfchsNKSIKLAKKLIDY
||| |.|.|  ..|. |.|.    .               | ||||.|. .|..||.|  |..| |.||....| |.|||  .    |....|.| |...
LhlAaengnlelvklLlekg....advdl...........getpLhlAaeagnleivklLleagadvnakdkegntaLhlAvr....nghlelvklLlek

GAYINHKD
|| .| .|
gadvnlrd
subfamily_pats1_pd Subfamily pats1 998-1080 2.5e-17 54.5 In-house 553-635 (691) alignment 
Range on Protein: 998-1080
Range on HMM: 553-635/691.0
SPIFQQFLDCCFQLCSQFPLLFEFTPTLLLFISDNIHSCKYGTFLNNCEKDRVQDQVKFKTTSIWSEVHFNIHKFLNPYYNPQ
|||| ||||  .||  .||. |||   ||| . .. .| ..|.|| .  |.... .|  .. |||| .. |  .|.| .| . 
sPifvqfldlvwqlqkefPfhfefneslllllvkesfssrfGnflyseakrdserkvlkrsksiwsfinqnksrfinllykhs
Ank_2 Ankyrin repeats (3 copies) 128-214 3.2e-17 50.8 Pfam-A 6-87 (89) alignment 
Range on Protein: 128-214
Range on HMM: 6-87/89.0
SNKSIKLAKKLIDYGAYINHkdskQETPLHRATmLNDNYDYLKLLLHHGANPNIVNKRGRTCQHISIEQGKVDLLELFLMYGADFNK
.|....|.|.|.. || ..     .||||| |   ..|.. .|||| .||..|  .|.|.|. |. ...|...|..| | .|||.| 
engnlelvklLlekgadvdl....getpLhlAa.eagnleivklLleagadvnakdkegntaLhlAvrnghlelvklLlekgadvnl
Ank_5 Ankyrin repeats (many copies) 70-121 1.1e-14 42.3 Pfam-A 5-55 (56) alignment 
Range on Protein: 70-121
Range on HMM: 5-55/56.0
GtNIVVDQRDKDGYTPLHCAVNQGSFEIAKKFLSRGSDPNARTESGSTPLHL
| ...|...|. |.|||| |...|. |.....| .|.|.|.|...| |.|.|
g.padvnatdeggntpLhlAakggalevvrlLlapgadlnlrdsdgltaldl
Ank Ankyrin repeat 81-112 6e-12 33.0 Pfam-A 1-32 (33) alignment 
Range on Protein: 81-112
Range on HMM: 1-32/33.0
DGYTPLHCAVNQGSFEIAKKFLSRGSDPNART
||.||||.|.  |. |..| .||.| |.||..
dGfTPLHlAalrgnlevvklLlsqGAdlnaqd
subfamily_MTMR5_pd Subfamily MTMR5 723-804 1.6e-11 35.7 In-house 12-93 (483) alignment 
Range on Protein: 723-804
Range on HMM: 12-93/483.0
KEYLRFNINIDENNNSNCYWRVTSINKEYKMCSSYSSSLVVLSKTLDKDLEKIFSFRSKGRIPSLSWKDPNSNASISRCSQP
..| |. ..  .. ... ..|....||.|..| || . .|| |.. |. ....     ..|.|   |... ..| . | ...
qdykRlGlgalngaskrgkfrisevNkkytvcrsYPalivvPsevsddsiarvakcfrqnRlPvvtWrhernkalLiRsggf
Ank_4 Ankyrin repeats (many copies) 82-125 1.2e-09 26.6 Pfam-A 1-44 (54) alignment 
Range on Protein: 82-125
Range on HMM: 1-44/54.0
GYTPLHCAVNQGSFEIAKKFLSRGSDPNARTESGSTPLHLLSKF
|.|.|| |...|  |..|  |..| |.|.. ||| |.||.  ..
gltaLhyaaisgrlelvklLlekgidinrtdesGntaLhiAalr
Ank Ankyrin repeat 153-184 1.6e-09 25.4 Pfam-A 3-33 (33) alignment 
Range on Protein: 153-184
Range on HMM: 3-33/33.0
ETPLHRATMLNdNYDYLKLLLHHGANPNIVNK
.|||| | . . |.. .|||| .||..|....
fTPLHlAalrg.nlevvklLlsqGAdlnaqdd
Ank_4 Ankyrin repeats (many copies) 165-206 2.4e-09 25.7 Pfam-A 13-54 (54) alignment 
Range on Protein: 165-206
Range on HMM: 13-54/54.0
NYDYLKLLLHHGANPNIVNKRGRTCQHISIEQGKVDLLELFL
.....|||| .|...| ....|.|. ||... | ...|.|.|
rlelvklLlekgidinrtdesGntaLhiAalrgnieilklLl
Ank_5 Ankyrin repeats (many copies) 138-188 3.5e-09 24.8 Pfam-A 1-51 (56) alignment 
Range on Protein: 138-188
Range on HMM: 1-51/56.0
LIDYG-AYINHKDSKQETPLHRATMlNDNYDYLKLLLHHGANPNIVNKRGRT
|...| | .|. | . .|||| | . . . . ..|||..||..|. ...|.|
LlehgpadvnatdeggntpLhlAak.ggalevvrlLlapgadlnlrdsdglt
Ank_4 Ankyrin repeats (many copies) 131-173 9.4e-09 23.7 Pfam-A 13-54 (54) alignment 
Range on Protein: 131-173
Range on HMM: 13-54/54.0
SIKLAKKLIDYGAYINHKDSKQETPLHRATmLNDNYDYLKLLL
 ..|.| |...|. ||..|....|.||.|  |. |.. |||||
rlelvklLlekgidinrtdesGntaLhiAa.lrgnieilklLl
Ank_3 Ankyrin repeat 81-110 1.9e-08 22.2 Pfam-A 1-30 (30) alignment 
Range on Protein: 81-110
Range on HMM: 1-30/30.0
DGYTPLHCAVNQGSFEIAKKFLSRGSDPNA
.|.||||.|. .|. |..|  |..| |.||
nGnTpLhlAasngrielvkyLlengadina
PTPc_DSPc_SM00012 914-972 2.4e-07 26.3 In-house 38-71 (105) alignment 
Range on Protein: 914-972
Range on HMM: 38-71/105.0
ShiksileaatfsadlilkGNSILVHCSDGWDRTPQITSLTQILLDPYYRTivgfqvlI
|                  .....||||.|..|| ... |  .| . ...|        
s..................skpvvVhCsaGvgRtgtfvaldillqqleket.......k
Ank_3 Ankyrin repeat 153-181 2.8e-07 18.7 Pfam-A 3-30 (30) alignment 
Range on Protein: 153-181
Range on HMM: 3-30/30.0
ETPLHRATMLNdNYDYLKLLLHHGANPNI
.|||| | . . ... .|.|| .||..|.
nTpLhlAasng.rielvkyLlengadina
IMCp Inner membrane complex protein 594-655 9.5e-07 15.5 Pfam-A 31-93 (97) alignment 
Range on Protein: 594-655
Range on HMM: 31-93/97.0
VRDKIMELISYHYKEKiERLIKVENQNKSIQKKI--AEEHIQMHDESRIQHIDRYESYGVFEES
..||| |.  |.||||     ||. . . |.|.    ...... .  .|...|||... ..|| 
yvdKivevpeyvykek.iyvpkvvikerviekpkiekkivekkvevpqikevdrykeveeveev
0051429 (Phosphotyrosine protein) phosphatases II 897-966 1.2e-06 23.9 In-house 115-183 (272) alignment 
Range on Protein: 897-966
Range on HMM: 115-183/272.0
ESTDMRWWGCIEETGWISHI---KSILEAATFSADlilkGNSILVHCSDGWDRTPQITSLTQILLDPYYRTIV
  ...|.. ..  |.|. |    ...||.  . .|    |. .||||| |.|||  .  |  .||.  . |||
sagearevmhlhytdwpdhgvpqeallellellld....ggpvlvHCsaGkdRTGtvvallllllgvsletiv
0045098 (Phosphotyrosine protein) phosphatases II 901-956 1.2e-06 23.6 In-house 158-229 (278) alignment 
Range on Protein: 901-956
Range on HMM: 158-229/278.0
MRWWGCIEETGWISHI--KSILEAATFSADLIL--------------KGNSILVHCSDGWDRTPQITSLTQI
. .. .... |. |.   ||.||.  |  . .               .|. .||||| |..||  .  .  .
hlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvlVHCsaGvgRtGtlvaaylm
Ank Ankyrin repeat 115-149 2.3e-06 15.4 Pfam-A 2-32 (33) alignment 
Range on Protein: 115-149
Range on HMM: 2-32/33.0
GSTPLHLLSKFChsnkSIKLAKKLIDYGAYINHKD
| ||||| ..      ... .| |...|| .|..|
GfTPLHlAalrg....nlevvklLlsqGAdlnaqd