Gene DDB_G0269272 in Dictyostelium discoideum

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family Myotubularin
Subfamily Ank-MTMR1
Protein sequence
ID Type Fasta BLAST phosphatome Note
DdisP022_AA protein Get Run
DdisP022_AA_714-1108 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_Ank-MTMR1_pd Subfamily Ank-MTMR1 701-1105 2.3e-287 944.1 In-house 1-405 (405) alignment
Range on Protein: 701-1105
Range on HMM: 1-405/405.0
NNQNNQNNNNNFINGWEIYNQKKEYLRFNINIDENNNSNCYWRVTSINKEYKMCSSYSSSLVVLSKTLDKDLEKIFSFRSKGRIPSLSWKDPNSNASISR
..|||.|.....|.|||.||||||||||||.|||.|.|||||.|||||||||||||||||||||||.|||||||||||||||||||||||||.|||||||
stqnnlnsstssidgwevynqkkeylrfniyideenssncywkvtsinkeykmcssyssslvvlskaldkdlekifsfrskgripslswkdpssnasisr

CSQPLVGIERSRCPEDELYCSNLALSAPSKTLYLIDARPKLNAYANTANGAGFENIHNYPNCKLVFMNIPNIHVIRKSLEKLTSSMRSSTRDKDHTESTD
||||||||||.||||||||||.|||||||||||||||||||||.||||||||||||||||||||||||||||||||||||||...|.||.||||||||||
csqplvgierarcpedelycsslalsapsktlylidarpklnaiantangagfenihnypncklvfmnipnihvirksleklvlamkssardkdhtestd

MRWWGCIEETGWISHIKSILEAATFSADLILKGNSILVHCSDGWDRTPQITSLTQILLDPYYRTIVGFQVLIEKEWLSFGHKFSLRLGHLPGNEEERSPI
||.||.|||||||||||||||||||||.||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
mrfwgyieetgwishiksileaatfsaelilkgnsilvhcsdgwdrtpqitsltqilldpyyrtivgfqvliekewlsfghkfslrlghlpgneeerspi

FQQFLDCCFQLCSQFPLLFEFTPTLLLFISDNIHSCKYGTFLNNCEKDRVQDQVKFKTTSIWSEVHFNIHKFLNPYYNPQDIQSIKPKLYSRCLELWKAC
|||||||||||.|||||||||||.|||||||||||||||||||||||||||||||.||.||||||..|..||||||||||||||||||||||||||||||
fqqfldccfqllsqfpllfeftpslllfisdnihsckygtflnncekdrvqdqvktktisiwsevnlnvnkflnpyynpqdiqsikpklysrclelwkac

YMRVE
|||||
ymrve

subfamily_MTMR1_pd Subfamily MTMR1 713-1105 2.5e-136 447.0 In-house 4-387 (389) alignment
Range on Protein: 713-1105
Range on HMM: 4-387/389.0
INGWEIYNQKKEYLRFNINIDEnnnsncYWRVTSINKEYKMCSSYSSSLVVLSKTLDKDLEKIFSFRSKGRIPSLSWKDPNSNASISRCSQPLVGIERSR
 .||..|. ..|. |  .  ..       ||.|..||.|..| .|.. |||.. . |.||.|. .||||||.|.||| .....|.|.|.||||||.. .|
edGWkvydpeaelerlgllnek......lWritklnkkyelcdtYpavlvvpkvvsdedlkkvaafrskgRlPvlswlnkenqavilrasqplvGlsgkr

CPEDELYCSNLALSA-PSKTLYLIDARPKLNAYANTANGAGFENIHNYPNCKLVFMNIPNIHVIRKSLEKLTSSMRSSTRDKdhtestdmRWWGCIEETG
..||| | ...  .   |. |...|||.. || || |.| | |. ..| |..|.|..|.||||.|.||.||   . ... ||        .|   .|.| 
skedekylqaileanaqsekllildarssvnavankakgkgyeseeaYknaelifldihnihvvReslkklkelvlpnvddk........kwlsalestk

WISHIKSILEAATFSADLIL-KGNSILVHCSDGWDRTPQITSLTQILLDPYYRTIVGFQVLIEKEWLSFGHKFSLRLGH--LPGNEEERSPIFQQFLDCC
|..|||.||..|.  .. .  . .|.||||||||||| |.|||...|||.||||| ||.||||||||||||||. ||||   . ...||||.| ||.|| 
WlehiklilagavkivekvetektsvlvhcsdGWDRtaqltsLamlllDsyyRtieGfevliekeWlsfGHkfkeRlghgdknssdaersPvFlqfiDcv

FQLCSQFPLLFEFTPTLLLFISDNIHSCKYGTFLNNCEKDRVQDQVKFKTTSIWSEVHFNIHKFLNPYYNPQ-DIQSIKPKLYSRCLELWKACYMRVE
.||  |||  |||. ..|... |...|| .|||| |.|| ||...|| ||.|.|| |. . ..| ||.|... . . . ||.. |.|||||  |.| .
wqltrqfptAFefneefLitlldhlysclfGtflfnsekervkekvkektvslwsyvnsskeeftnplyaeelekkvlypkaslrrlelWkeyylrwn

subfamily_Dicty-MTMR1-like_pd Subfamily Dicty-MTMR1-like 705-1104 1.8e-132 434.3 In-house 5-402 (404) alignment
Range on Protein: 705-1104
Range on HMM: 5-402/404.0
NQNNNNNFINGWEIYNQKKEYLRFNINIDEnnnsncYWRVTSINKEYKMCSSYSSSLVVLSKTLDKDLEKIFSFRSKGRIPSLSWKDPNSNASISRCSQP
....  .  .|| ||....|| | .|. .        ||...||..|..|..| . ||| ..  |..|.|..||||||||| |||. ...|..|.|.|||
ysekksvledgwliydaeeEykRlgikses......eWriskinsdyelcetYPkllvvPesisDeelkkvasfRskgRiPvlswrhrsknstitRssqp

LVGIERSRCPEDELYCSNLALSAP-SKTLYLIDARPKLNAYANTANGAGFENIHNYPNCKLVFMNIPNIHVIRKSLEKLTSSMRSSTRDkdhtestDMRW
|||...||. |||..   . .... ..|||..|||||.|| ||.|.|||.|.|..| ||.. |.|| ||| .|.||.||. ...|....       .  |
lvGltksrseedEklinsirkaktqletlyildarpkanavansakgagyedisryenceieflnienihelreslkklkkavnsiiek.......eknw

WGCIEETGWISHIKSILEAATFSADLIL-KGNSILVHCSDGWDRTPQITSLTQILLDPYYRTIVGFQVLIEKEWLSFGHKFSLRLGH-LPGNEEERSPIF
.  .|...|. |||..||...  ..||  ...|.|||||||||||.|..||.|.||||||||| ||.||||||||||||||  | |.    ...||||||
lselessrWldhiklllegskriveliekekssvlvhcsdgwDrtsqlsslsqllldpyyrtiegFivliekewlsfGhkfaqRigqttekssdersPif

QQFLDCCFQLCSQFPLLFEFTPTLLLFISDNIHSCKYGTFLNNCEKDRVQDQVKFKTTSIWSEVHFNIHKFLNPYYNPQDIQSIKPKLY--------SRC
 ||.||..||  |||  |||   .|. | |.. ||..|||| ..||.|.|......|.|.|.... | ...|||.|  .. .. . .           . 
lqFidcvyqltkqfptsFeFnekflikildalyscrfgtFLydsekeRqqnnlaketvslWalleankseylnplyilekkeqkenitssessssadikl

LELWKACYMRV
..||.  |.| 
iklWseyylrw

subfamily_MTMR6_pd Subfamily MTMR6 704-1105 1.1e-127 418.7 In-house 7-396 (397) alignment
Range on Protein: 704-1105
Range on HMM: 7-396/397.0
NNQNNNNNFINGWEIYNQKKEYLRFNInidennnSNCYWRVTSINKEYKMCSSYSSSLVVLSKTLDKDLEKIFSFRSKGRIPSLSWKDPNSNASISRCSQ
........  .||. .. |.|| |  .       .| .| .|..||.|..|..|...|.| ...  . |     ||||||.| ||.   . .|.| ||||
kpkkdkeekvsGwklldlkaeytrmgv.......pnekwtltdlnkdyelcdtyprelyvPksatkevlvgsskfrskgrlPvlsylhkeneaaicrcsq

PLVGIERsRCPEDELYCSNLALSAP-SKTLYLIDARPKLNAYANTANGAGFENIHNYPNCKLVFMNIPNIHVIRKSLEKLTSSMRSSTRDKDhtestdmR
|| |... || |||     .  . | |..||..|.|||||| || |.| |.|| .|| |.|. |..| ||||.|.||.||   .. .....         
plsgfsa.rcledeklleairkanpnsellyvvdtrpklnalankaagkGyenednysnikfqfvgienihvmreslqkllevvelksksvs.......e

WWGCIEETGWISHIKSILEAATFSADLI-LKGNSILVHCSDGWDRTPQITSLTQILLDPYYRTIVGFQVLIEKEWLSFGHKFSLRLGHLPGNEEERSPIF
.. ..|..||. |||..|.|..| |  .  .| |.||||||||||| |..||...||||||||| ||.||||||||||||||| | |.| ... | ||||
flsglessgwlkhikavldasifiakavaeegasvlvhcsdGwdrtaqvcslasllldpyyrtikGflvliekewlsfGhkfsercGlldedskevsPif

QQFLDCCFQLCSQFPLLFEFTPTLLLFISDNIHSCKYGTFLNNCEKDRVQDQVKFKTTSIWSEVHFNIHKFLNPYYNPQDI-QSIKPKLYSRCLELWKAC
.|||.| .||..|||  |||  . || . | ..||..|||| |||||| . ..| .|.|.|. .. . ...|||.|...   . .||.. . .|.||.| 
tqflecvwqlleqfpkafefnerfllelhdhvyscqfGtflgncekdrrdlklkertkslwayllerkddylnplykaetekevlkpdtapaalklwral

YMRVE
|.| .
ynrfd

0040695 (Phosphotyrosine protein) phosphatases II 712-1104 1e-125 413.3 In-house 4-385 (388) alignment
Range on Protein: 712-1104
Range on HMM: 4-385/388.0
FINGWEIYNQKKEYLRFNINIDennnsncYWRVTSINKEYKMCSSYSSSLVVLSKTLDKDLEKIFSFRSKGRIPSLSWKDPNSNASISRCSQPLVGIERS
 ..|| .|. ..|. | ....|       .||....|..|..|.|| . ||| .   |..|.....|||||||| ||.. ||..|.. |.||||||.  |
leegwslydilrelkrlglgld.......lwrisivNenyelcpsYPallvVPksisdellkrvarfrskgriPvlsyrhpnngavllRssqplvgllls

RCPEDELYCSNLA-LSAPSKTLYLIDARPKLNAYANTANGAGFENIHNYPNCKLVFMNIPNIHVIRKSLEKLTSSMrsstrdkdH-----TestdmRWWG
|. ||| ... .  |  ....|...|.||||||.||.| | |.||...|||..|.|.|||||||.|.|| ||.. .              .     ... 
rsledeklleailkllpnlskllivdlrpklnalanralgggvenedaypnaeliflnipnihvvreslqklldac........lnvpdsl.....nlls

CIEETGWISHIKSILEAATFSADLILKGNS-ILVHCSDGWDRTPQITSLTQILLDPYYRTIVGFQVLIEKEWLSFGHKFSLRLGHLPG--NEEERSPIFQ
 .||.||...||.|||.| . ..|. .||| .|||||||||||.|..||.|.||||||||. |||||||||||||||||. |||||..  . .|.||.| 
lleesgwldliklilelavlivklldlgnssvlvhcsdgwdrtsqlssLaqllldPyYRTleGFqvLiekeWlsfghkfadRlghleseidskefsPvFl

QFLDCCFQLCSQFPLLFEFTPTLLLFISDNIHSCKYGTFLNNCEKDRVQDQVKFKTTSIWSEVHFNIHKFLNPYYNPQDIQSIKPKLYSRCLELWKACYM
.|||| .||  |||. |||...||||. | ..|| .|||| |.||.|.. .|  .| |.|| .  .  .||||.|.|   . ..| |  ..| ||  .|.
lFLdcvwqLlrqfPtaFeFnerlLlfLadhlyscrfgtFlfnsekerlelsvsertlslwsyllsrkseflnplYdpsslevllpslsvldlllWleyyl

RV
|.
rw

Myotubularin-like phosphatase domain 700-1051 4.9e-120 393.5 Pfam-A 7-352 (353) alignment
Myotubularin-like phosphatase domain 700-1051 4.9e-120 393.5 In-house 7-352 (353) alignment
subfamily_MTMR3_pd Subfamily MTMR3 827-1102 9e-90 294.5 In-house 170-440 (442) alignment
Range on Protein: 827-1102
Range on HMM: 170-440/442.0
APSKTLYLIDARPKLNAYANTANGAGFENIHNYPNCKLVFMNIPNIHVIRKSLEKLTSSMRsSTRDkdhtestDMRWWGCIEETGWISHIKSILEAATFS
  .|.| ..|||    |.|| | | |.|.   ||||..||....||| .|||...| . .  .. |       ...|.. .|.| |. ..  .|.||   
eekkkllivdarsytaafanrakgGGceleeyypncevvflglanihavrksfnslralls.qspd.......esnwlsalektkWlqnlsvllkaavkv

ADLILK-GNSILVHCSDGWDRTPQITSLTQILLDPYYRTIVGFQVLIEKEWLSFGHKFSLRLGHLPGNE--EERSPIFQQFLDCCFQLCSQFPLLFEFTP
.. . | | ..|||||||||||.||..|...||||||||. ||.||.|.|||.|||||. | || .  .  .||.|.| |.||.  ||  ||| .|||. 
veavdkegrpvlvhCsdGWdrttqivalakllldpyyrtleGfkvlvereWldfGhkfadrcghgenvddanercPvflqwldavhqlqrqfPtsfefne

TLLLFISDNIHSCKYGTFLNNCEKDRVQDQVKFKTTSIWSEVHFNIHKFLNPYYNPQDIQSIKPKLYSRCLELWKACYM
. |. .    .|| .|||| |.||.| ...|| .| |.|| .. . ... |  |.... . . |.   | |.||.. |.
aflvklvqhtysclfGtflansekereeekvkertlsvWsllrakekeyrnllykekteavllpavsvrelklwsevyl

subfamily_MTMR9_pd Subfamily MTMR9 714-1104 1.2e-89 293.1 In-house 13-392 (393) alignment
Range on Protein: 714-1104
Range on HMM: 13-392/393.0
NGWEIYNQKKEYLRFNInidennnSNCYWRVTSINKEYKMCSSYSSSLVVLSKTLDKDLEKIFSFRSKGRIPSLSWKDPNSNASISRCSQPLVGIERSRC
.|.. .....|. .          . . ||..|.||..|.|.|| .|..|  .  |..|... .||..||.| ||. . . .| . |.||||.| .  ||
dgysafdrenefaklis.......asdewRissvNknfkvcasypesvivPkaiddeelkasaafreggrfPvLsylhketkavllrssqplcgssgkrc

PEDELYCsNLALSAPsKTLYLIDARPKLNAYANTANGAGFENIHNYPNCKLVFMNIPNIHVIRKSLEKLTSSMRSSTRDKDhtestdmRWWGCIEETGWI
 |||    ||.|..  |  . .| | |  | .. ..|.|.|  ..|.. | .  .. ....| .|| ||  ..   . ..|       ...  .|..||.
kedekll.nlvlkkl.kkGlivdtrsksaaenarskgggietevkysqwkkasrslesvasiqdslaklleacsdaglstd.......kflsrleksgwl

SHIKSILEAATFSADLILK-GNSILVHCSDGWDRTPQITSLTQILLDPYYRTIVGFQVLIEKEWLSFGHKFSLRLGHLPGNE---EERSPIFQQFLDCCF
|... .||||.  |... . |....|| ..| | | |.|||.|..|||..||. ||. |||.||.  || |. |  ..  .|   ....|.|  |||| .
sqvadlleaalvvaqcldeegapvvvhgeeGlDatlqvtsLaqlildpdaRtvrgfealiereWiqaGHPFasRaskvaaketkkklsgpvfllFLDcvy

QLCSQFPLLFEFTPTLLLFISDNIHSCKYGTFLNNCEKDRVQDQVKFKTTSIWSEVH--FNIHKFLNPYYNPqDIQSIKPKLYSRCLELWKACYMRV
|. ||||. |||  .|| ..  . .|...|||| ..|. | . ..| ||.|.|| |.   ....|||| |.. . . | |     .||||.  |.| 
qilsqfpasFEFneelLillfehsyssqfgtflcdneaerkelklkkktvslwsyvnrpeklkqflnplyea.naeviwpsvapqslelWselylrw

subfamily_MTMR5_pd Subfamily MTMR5 855-1098 7.1e-56 182.0 In-house 221-476 (483) alignment
Range on Protein: 855-1098
Range on HMM: 221-476/483.0
NIHNYPNCKLVFMNIPNIHVIRKSLEKLTSSMRSSTRdkdHTESTDMRWWGCIEETGWISHIKSILEAATFSADLIL-KGNSILVHCSDGWDRTPQITSL
... . .. .. .....|  ...|..||     .||.    .|..   .   .|.  |.. |.|.|. ..  .||.  .| |.||   |||| | |..||
ksevdskaefipvelveirqvkasfkkllraClpsta...veeaesqsFlksvedseWlqqissllqlsgavvdlldlqgssvlvslEdGwdvtaqvssl

TQILLDPYYRTIVGFQVLIEKEWLSFGHKFSLRLGHLPGNEE-ERSPIFQQFLDCCFQLCSQFPLLFEFTPTLLLFISDNIHSCKYGTFLNNCEKDRVQD
.|.||||||||. ||.||.|||||.|||.|. |  . . ...   .|.| ||||| .|. .|||| |||    | |..    |... ||| ..|..|.. 
aqllldpyYRtleGFkvLveKEWLafGHrFtkrsnqtlsaqssgfaPvFlqFLDcvhqvsrqfPlafefndfylkflayhsvsnrfrtfllDseyerles

QV----------KFKTTSIWSEVHFN---IHKFLNPYYNPQDIQSIKPKLYSRCLELWK
..          |  ..|.|  .. .      | |  |.|.. . ..|.     |..|.
gllyeekaekrakkagksvwdyidrqhkrspifynflyspdesevlrPssnvsslkvWd

subfamily_MTMR10_pd Subfamily MTMR10 730-1100 9.7e-47 151.5 In-house 14-311 (380) alignment
Range on Protein: 730-1100
Range on HMM: 14-311/380.0
INIDENNNSNCYWRVTSINKEYKMCSSYSSSLVVLSKTLDKDLEKIFSFRSKGRIPSLSWKDPNSNASIsRCSQplVGIERSRCPEDELYCSNLALSAPS
..  |...... ..|.  |.  . . ..   .||. .  |.|.|...    ..| | ..|. ....| . |.|.   .   |  .|.|     |. .. .
leekekktvsdaivvllknelfaaaqtlPqyfvvpnslsdsdverlsrhykesRfplwvwshakgaall.rlsa..lqeaesadkekeekmlelvrkchp

KTlylidarpklnayantangagfenihnypNCKL--VFMNIPNIHVIRKSLEKLTSSMRSSTRDKdhTESTDMRWWGCIEETGWISHIKSILEAATFSA
                               . ||  .  ..|.|. . |. .|| .    .|  .    ..| .| . .|.|.|.  .. .|. |.  .
an.............................dvklvdlsdelpsiqdvqkaylklreLcvidtsee..fvtlddkwlssLektrWLayvrlclstasdav

DLI-LKGNSILVHCSDGWDRTPQITSLTQILLDPYYRTIVGFQVLIEKEWLSFGHKFSLRLGHLPGNEEERSPIFQQFLDCCFQLCSQFPLLFEFTPTLL
...  |..|...  |.| |    . ||.|..|||.|||| ||| ||.||| . ||.|  ||||.  .|...||.|  ||||  ||  |||  ||||.|.|
ktvvekkrsvilqesegrDlscvvaSLaqlmldphyrtisGfqsliqkewvaaghpfldrlghikpseksespvfllFldcvdqlleqfpseFeFtetfL

LFISDNIHSCKYGTFLNNCEKDRVQDQVKFKttsiwsevhfnihkflnpyynpqdiqsikpklysrclelwkaC
. . |  ||. ..||| |.|. |..  |. .                                          .
ialwdsshsgifltflfnseeqrlkavvsss..........................................p

subfamily_pats1_pd Subfamily pats1 861-989 2.2e-25 81.1 In-house 335-459 (691) alignment
Range on Protein: 861-989
Range on HMM: 335-459/691.0
NCKLVFMNIPNIHVIRKSLEKLTSSMRSStrdkDhtesTDMRWWGCIEETGWISHIKSILEAATFSADLILKGNSILVH-CSDGWDRTPQI---TSLTQI
 ....|...|  . ...   .|  |. |     |      .  |  |||  |.  .| .||||   . |. .|.|.|..  .|. . . ..   .||.|.
ssniiflslPtrekveerffdllqsilsl....d....gsddewkeieeskwvdsvkllleaavkvsnlldeGssvllknsidsPlieldlasisslaqv

LLDPYYRTIVGFQVLIEKEWLSFGHKFSLRLGH
|.||.|||. ||.|||||||||.|. || .  |
lsdPfyrtldGfkvliekewlsyGfPfskinyh

subfamily_MTMR3_pd Subfamily MTMR3 716-824 1.2e-22 73.3 In-house 17-126 (442) alignment
Range on Protein: 716-824
Range on HMM: 17-126/442.0
WEIYNQKKEYLRFNINIDENN-NSNCYWRVTSINKEYKMCSSYSSSLVVLSKTLDKDLEKIFSFRSKGRIPSLSWKDPNSNASISRCSQPLVGIERSRCP
. . ....   .......    . .  ||....|...|.|||| . |.| ..  |.||.|  |||| .|.|.. |.  .. | . ||||| ||.   |. 
fllraasvaeeklkeeverlGfdlkeawrisdvnsdfklCssyPkklivPksitdddlkkvasfrslkrlPavvwrhkkngavlarcsqPevgwlgWrna

EDELYCSNLA
|||   ...|
edekllkaia

Ank_2 Ankyrin repeats (3 copies) 45-149 9.3e-19 55.7 Pfam-A 1-89 (89) alignment
Range on Protein: 45-149
Range on HMM: 1-89/89.0
LHLIAMNDNMVALKFYLKKKyvvfK---GtnivvdqrdkdGYTPLHCAVNQGSFEIAKKFLSRGSDPNARTESGSTPLHLLSKfchsNKSIKLAKKLIDY
||| |.|.|  ..|. |.|.    .               | ||||.|. .|..||.|  |..| |.||....| |.|||  .    |....|.| |...
LhlAaengnlelvklLlekg....advdl...........getpLhlAaeagnleivklLleagadvnakdkegntaLhlAvr....nghlelvklLlek

GAYINHKD
|| .| .|
gadvnlrd

subfamily_pats1_pd Subfamily pats1 998-1080 2.5e-17 54.5 In-house 553-635 (691) alignment
Range on Protein: 998-1080
Range on HMM: 553-635/691.0
SPIFQQFLDCCFQLCSQFPLLFEFTPTLLLFISDNIHSCKYGTFLNNCEKDRVQDQVKFKTTSIWSEVHFNIHKFLNPYYNPQ
|||| ||||  .||  .||. |||   ||| . .. .| ..|.|| .  |.... .|  .. |||| .. |  .|.| .| . 
sPifvqfldlvwqlqkefPfhfefneslllllvkesfssrfGnflyseakrdserkvlkrsksiwsfinqnksrfinllykhs

Ank_2 Ankyrin repeats (3 copies) 128-214 3.2e-17 50.8 Pfam-A 6-87 (89) alignment
Range on Protein: 128-214
Range on HMM: 6-87/89.0
SNKSIKLAKKLIDYGAYINHkdskQETPLHRATmLNDNYDYLKLLLHHGANPNIVNKRGRTCQHISIEQGKVDLLELFLMYGADFNK
.|....|.|.|.. || ..     .||||| |   ..|.. .|||| .||..|  .|.|.|. |. ...|...|..| | .|||.| 
engnlelvklLlekgadvdl....getpLhlAa.eagnleivklLleagadvnakdkegntaLhlAvrnghlelvklLlekgadvnl

Ank_5 Ankyrin repeats (many copies) 70-121 1.1e-14 42.3 Pfam-A 5-55 (56) alignment
Range on Protein: 70-121
Range on HMM: 5-55/56.0
GtNIVVDQRDKDGYTPLHCAVNQGSFEIAKKFLSRGSDPNARTESGSTPLHL
| ...|...|. |.|||| |...|. |.....| .|.|.|.|...| |.|.|
g.padvnatdeggntpLhlAakggalevvrlLlapgadlnlrdsdgltaldl

Ank Ankyrin repeat 81-112 6e-12 33.0 Pfam-A 1-32 (33) alignment
Range on Protein: 81-112
Range on HMM: 1-32/33.0
DGYTPLHCAVNQGSFEIAKKFLSRGSDPNART
||.||||.|.  |. |..| .||.| |.||..
dGfTPLHlAalrgnlevvklLlsqGAdlnaqd

subfamily_MTMR5_pd Subfamily MTMR5 723-804 1.6e-11 35.7 In-house 12-93 (483) alignment
Range on Protein: 723-804
Range on HMM: 12-93/483.0
KEYLRFNINIDENNNSNCYWRVTSINKEYKMCSSYSSSLVVLSKTLDKDLEKIFSFRSKGRIPSLSWKDPNSNASISRCSQP
..| |. ..  .. ... ..|....||.|..| || . .|| |.. |. ....     ..|.|   |... ..| . | ...
qdykRlGlgalngaskrgkfrisevNkkytvcrsYPalivvPsevsddsiarvakcfrqnRlPvvtWrhernkalLiRsggf

Ank_4 Ankyrin repeats (many copies) 82-125 1.2e-09 26.6 Pfam-A 1-44 (54) alignment
Range on Protein: 82-125
Range on HMM: 1-44/54.0
GYTPLHCAVNQGSFEIAKKFLSRGSDPNARTESGSTPLHLLSKF
|.|.|| |...|  |..|  |..| |.|.. ||| |.||.  ..
gltaLhyaaisgrlelvklLlekgidinrtdesGntaLhiAalr

Ank Ankyrin repeat 153-184 1.6e-09 25.4 Pfam-A 3-33 (33) alignment
Range on Protein: 153-184
Range on HMM: 3-33/33.0
ETPLHRATMLNdNYDYLKLLLHHGANPNIVNK
.|||| | . . |.. .|||| .||..|....
fTPLHlAalrg.nlevvklLlsqGAdlnaqdd

Ank_4 Ankyrin repeats (many copies) 165-206 2.4e-09 25.7 Pfam-A 13-54 (54) alignment
Range on Protein: 165-206
Range on HMM: 13-54/54.0
NYDYLKLLLHHGANPNIVNKRGRTCQHISIEQGKVDLLELFL
.....|||| .|...| ....|.|. ||... | ...|.|.|
rlelvklLlekgidinrtdesGntaLhiAalrgnieilklLl

Ank_5 Ankyrin repeats (many copies) 138-188 3.5e-09 24.8 Pfam-A 1-51 (56) alignment
Range on Protein: 138-188
Range on HMM: 1-51/56.0
LIDYG-AYINHKDSKQETPLHRATMlNDNYDYLKLLLHHGANPNIVNKRGRT
|...| | .|. | . .|||| | . . . . ..|||..||..|. ...|.|
LlehgpadvnatdeggntpLhlAak.ggalevvrlLlapgadlnlrdsdglt

Ank_4 Ankyrin repeats (many copies) 131-173 9.4e-09 23.7 Pfam-A 13-54 (54) alignment
Range on Protein: 131-173
Range on HMM: 13-54/54.0
SIKLAKKLIDYGAYINHKDSKQETPLHRATmLNDNYDYLKLLL
 ..|.| |...|. ||..|....|.||.|  |. |.. |||||
rlelvklLlekgidinrtdesGntaLhiAa.lrgnieilklLl

Ank_3 Ankyrin repeat 81-110 1.9e-08 22.2 Pfam-A 1-30 (30) alignment
Range on Protein: 81-110
Range on HMM: 1-30/30.0
DGYTPLHCAVNQGSFEIAKKFLSRGSDPNA
.|.||||.|. .|. |..|  |..| |.||
nGnTpLhlAasngrielvkyLlengadina

PTPc_DSPc_SM00012 914-972 2.4e-07 26.3 In-house 38-71 (105) alignment
Range on Protein: 914-972
Range on HMM: 38-71/105.0
ShiksileaatfsadlilkGNSILVHCSDGWDRTPQITSLTQILLDPYYRTivgfqvlI
|                  .....||||.|..|| ... |  .| . ...|        
s..................skpvvVhCsaGvgRtgtfvaldillqqleket.......k

Ank_3 Ankyrin repeat 153-181 2.8e-07 18.7 Pfam-A 3-30 (30) alignment
Range on Protein: 153-181
Range on HMM: 3-30/30.0
ETPLHRATMLNdNYDYLKLLLHHGANPNI
.|||| | . . ... .|.|| .||..|.
nTpLhlAasng.rielvkyLlengadina

IMCp Inner membrane complex protein 594-655 9.5e-07 15.5 Pfam-A 31-93 (97) alignment
Range on Protein: 594-655
Range on HMM: 31-93/97.0
VRDKIMELISYHYKEKiERLIKVENQNKSIQKKI--AEEHIQMHDESRIQHIDRYESYGVFEES
..||| |.  |.||||     ||. . . |.|.    ...... .  .|...|||... ..|| 
yvdKivevpeyvykek.iyvpkvvikerviekpkiekkivekkvevpqikevdrykeveeveev

0051429 (Phosphotyrosine protein) phosphatases II 897-966 1.2e-06 23.9 In-house 115-183 (272) alignment
Range on Protein: 897-966
Range on HMM: 115-183/272.0
ESTDMRWWGCIEETGWISHI---KSILEAATFSADlilkGNSILVHCSDGWDRTPQITSLTQILLDPYYRTIV
  ...|.. ..  |.|. |    ...||.  . .|    |. .||||| |.|||  .  |  .||.  . |||
sagearevmhlhytdwpdhgvpqeallellellld....ggpvlvHCsaGkdRTGtvvallllllgvsletiv

0045098 (Phosphotyrosine protein) phosphatases II 901-956 1.2e-06 23.6 In-house 158-229 (278) alignment
Range on Protein: 901-956
Range on HMM: 158-229/278.0
MRWWGCIEETGWISHI--KSILEAATFSADLIL--------------KGNSILVHCSDGWDRTPQITSLTQI
. .. .... |. |.   ||.||.  |  . .               .|. .||||| |..||  .  .  .
hlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvlVHCsaGvgRtGtlvaaylm

Ank Ankyrin repeat 115-149 2.3e-06 15.4 Pfam-A 2-32 (33) alignment
Range on Protein: 115-149
Range on HMM: 2-32/33.0
GSTPLHLLSKFChsnkSIKLAKKLIDYGAYINHKD
| ||||| ..      ... .| |...|| .|..|
GfTPLHlAalrg....nlevvklLlsqGAdlnaqd