Gene DDB_G0278311 in Dictyostelium discoideum

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family Myotubularin
Subfamily DdisMTMR1-like
Protein sequence
ID Type Fasta BLAST phosphatome Note
DdisP025_AA protein Get Run
DdisP025_AA_491-900 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_Dicty-MTMR1-like_pd Subfamily Dicty-MTMR1-like 475-895 4e-186 611.0 In-house 1-402 (404) alignment 
Range on Protein: 475-895
Range on HMM: 1-402/404.0
FCYNLRQEYTRLElvgLGWTLYSARDEYARMGVPSP-DWRVSDANYNYFICDSYPGLMGVPESITDEQLKSVAQFRSKGRIPVLSYRHWSNKCSITRCSQ
|..........||    ||..|.|..||.|.|..|  .||.|..|..| .|..|| |. |||||.||.||.||.|||||||||||.||.|....|||.||
fafsysekksvle...dgwliydaeeEykRlgikseseWriskinsdyelcetYPkllvvPesisDeelkkvasfRskgRiPvlswrhrsknstitRssq

PMVGIGGNRSTEDENLLNSIRMTSTAGSgssggsggsgsgsnkennssdrTLYILDCRPYANAVGNRAKGAGWEILNNYPGCTLEFLNIANIHSMRHSLW
|.||....||.|||.|.||||...|...                      ||||||.||.|||| |.|||||.| ...| .|..|||||.|||..|.||.
plvGltksrseedEklinsirkaktqle......................tlyildarpkanavansakgagyedisryenceieflnienihelreslk

KIKDAAVSSIDKEDGWFNQLESSGWFGHIKLVIQGATRLAKLIHLQHHNVLVHCSDGWDRTSQLVSLAELLLDPYFRTIRGFQILIEKEWLSFGHKFAQR
|.|.|. |.|.||..|...||||.|..||||...|..|...||. ....|||||||||||||||.||..||||||.|||.||..||||||||||||||||
klkkavnsiiekeknwlselessrWldhiklllegskriveliekekssvlvhcsdgwDrtsqlsslsqllldpyyrtiegFivliekewlsfGhkfaqR

CGQVHGKDESEQSPILYQFIEACYQIIHQFPSKFEFNANFLKTILYHSYSGKYGNFLFNTEKERVQNHIYGKTISLWAEMDGNLKEYINPLYQPTGIKER
.|| ..|...|.|||..|||...||...|||..||||..||..||...||...|.||...||||.||... .|.||||... | .||.||||. .  ...
igqttekssdersPiflqFidcvyqltkqfptsFeFnekflikildalyscrfgtFLydsekeRqqnnlaketvslWalleankseylnplyilekkeqk

DVIFPDC-----SIKRFKVWKQLYFNQ
. |. ..     .||..|.|...|...
enitssessssadikliklWseyylrw
0040695 (Phosphotyrosine protein) phosphatases II 492-894 1.5e-136 449.0 In-house 7-384 (388) alignment 
Range on Protein: 492-894
Range on HMM: 7-384/388.0
GWTLYSARDEYARMGVPSPDWRVSDANYNYFICDSYPGLMGVPESITDEQLKSVAQFRSKGRIPVLSYRHWSNKCSITRCSQPMVGIGGNRSTEDENLLN
||.||.   |. |.|..   ||.|. | || .|.|||.|. || ||.||.||.||.||||||||||||||. |.....|.|||.||. ..|| ||| ||.
gwslydilrelkrlglgldlwrisivNenyelcpsYPallvVPksisdellkrvarfrskgriPvlsyrhpnngavllRssqplvglllsrsledeklle

SIRMTSTagsgssggsggsgsgsnkennsSDRTLYILDCRPYANAVGNRAKGAGWEILNNYPGCTLEFLNIANIHSMRHSLWKIKDAAvSSIDKEDGWFN
.|. . .                      . ..|.|.|.||..||. |||.| |.|. ..|| ..| |||| ||| .| ||.|. ||   ... .. ...
ailkllp......................nlskllivdlrpklnalanralgggvenedaypnaeliflnipnihvvreslqklldac.lnvpdslnlls

QLESSGWFGHIKLVIQGATRLAKLIHLQHHNVLVHCSDGWDRTSQLVSLAELLLDPYFRTIRGFQILIEKEWLSFGHKFAQRCGQVH-GKDESEQSPILY
 ||.|||. .|||....|  ..||..|....|||||||||||||||.|||.||||||.||..|||.||||||||||||||.|.|..   .| .| ||. .
lleesgwldliklilelavlivklldlgnssvlvhcsdgwdrtsqlssLaqllldPyYRTleGFqvLiekeWlsfghkfadRlghleseidskefsPvFl

QFIEACYQIIHQFPSKFEFNANFLKTILYHSYSGKYGNFLFNTEKERVQNHIYGKTISLWAEMDGNLKEYINPLYQPTGIKerdVIFPDCSIKRFKVWKQ
.|... .|...|||. |||| ..|.....|.||. .|.||||.||||...... .|.|||  .  . .|..||||.|.      |..| .|.  ...| .
lFLdcvwqLlrqfPtaFeFnerlLlfLadhlyscrfgtFlfnsekerlelsvsertlslwsyllsrkseflnplYdpssle...vllpslsvldlllWle

LYFN
.|..
yylr
Myotub-related Myotubularin-like phosphatase domain 474-839 2.1e-128 421.0 Pfam-A 2-352 (353) alignment
Myotub-related Myotubularin-like phosphatase domain 474-839 2.1e-128 421.0 In-house 2-352 (353) alignment
subfamily_MTMR3_pd Subfamily MTMR3 497-894 1.5e-127 419.1 In-house 28-441 (442) alignment 
Range on Protein: 497-894
Range on HMM: 28-441/442.0
SARDEYARMGVP-SPDWRVSDANYNYFICDSYPGLMGVPESITDEQLKSVAQFRSKGRIPVLSYRHWSNKCSITRCSQPMVGIGGNRSTEDENLLNSIRM
. . |..|.|   .  ||.||.| .. .| |||  . ||.||||..||.||.||| .|.|.. .|| .|.. ..||||| ||. | |..|||.||..|  
klkeeverlGfdlkeawrisdvnsdfklCssyPkklivPksitdddlkkvasfrslkrlPavvwrhkkngavlarcsqPevgwlgWrnaedekllkaiak

TSTAGSG--SSGGSGGSGSG---------------SNKE-NNSSDRTLYILDCRPYANAVGNRAKGAGWEILNNYPGCTLEFLNIANIHSMRHSLWKIKD
...  .|  ..|..  .|                 |..|   .  ..| |.| | |. |..||||| | |  . || | ..||..||||..|.|. ... 
acaldagekakgeklsngkakkkdvsdaldaeadaseeeslaeekkkllivdarsytaafanrakgGGceleeyypncevvflglanihavrksfnslra

AAVSSIDkEDGWFNQLESSGWFGHIKLVIQGATRLAKLIHLQHHNVLVHCSDGWDRTSQLVSLAELLLDPYFRTIRGFQILIEKEWLSFGHKFAQRCGQV
   .| | |  |. .||.  |. ..  ... | .... .. . . ||||||||||||.|.|.||.||||||.||..||..|.|.|||.|||||| |||. 
llsqspd.esnwlsalektkWlqnlsvllkaavkvveavdkegrpvlvhCsdGWdrttqivalakllldpyyrtleGfkvlvereWldfGhkfadrcghg

HGKDE-SEQSPILYQFIEACYQIIHQFPSKFEFNANFLKTILYHSYSGKYGNFLFNTEKERVQNHIYGKTISLWAEMDGNLKEYINPLYQPTgikERDVI
. .|.  |..|.. |...| .|. .|||. ||||  ||  .. |.||. .| ||.|.|||| ..... .|.|.|. .  . ||| | ||...   .  |.
envddanercPvflqwldavhqlqrqfPtsfefneaflvklvqhtysclfGtflansekereeekvkertlsvWsllrakekeyrnllykek...teavl

FPDCSIKRFKVWKQLYFN
.| .|.. .|.|...| .
lpavsvrelklwsevyle
subfamily_MTMR1_pd Subfamily MTMR1 618-894 7.2e-105 343.4 In-house 111-385 (389) alignment 
Range on Protein: 618-894
Range on HMM: 111-385/389.0
NNSSDRTLYILDCRPYANAVGNRAKGAGWEILNNYPGCTLEFLNIANIHSMRHSLWKIKDAAVSSIDkEDGWFNQLESSGWFGHIKLVIQGATRLAKLIH
 |.. . |.||| |. .|||.|.||| | |  ..|  ..| ||.|.|||..|.|| |.|.......| .. |...|||. |. ||||...||..... ..
anaqsekllildarssvnavankakgkgyeseeaYknaelifldihnihvvReslkklkelvlpnvd.dkkwlsalestkWlehiklilagavkivekve

LQHHNVLVHCSDGWDRTSQLVSLAELLLDPYFRTIRGFQILIEKEWLSFGHKFAQRCGQVH-GKDESEQSPILYQFIEACYQIIHQFPSKFEFNANFLKT
 ....||||||||||||.||.||| ||||.|.|||.||..|||||||||||||..| |.    . ..|.||.  |||.. .|. .|||. ||||..|| |
tektsvlvhcsdGWDRtaqltsLamlllDsyyRtieGfevliekeWlsfGHkfkeRlghgdknssdaersPvFlqfiDcvwqltrqfptAFefneefLit

ILYHSYSGKYGNFLFNTEKERVQNHIYGKTISLWAEMDGNLKEYINPLYQPTGIkeRDVIFPDCSIKRFKVWKQLYFN
.| |.||. .|.||||.|||||..... ||.|||. .. . .|..||||...    ..|..| .|..| ..||. |  
lldhlysclfGtflfnsekervkekvkektvslwsyvnsskeeftnplyaeele..kkvlypkaslrrlelWkeyylr
subfamily_MTMR6_pd Subfamily MTMR6 617-893 1.5e-98 322.7 In-house 120-393 (397) alignment 
Range on Protein: 617-893
Range on HMM: 120-393/397.0
ENNSSDRTLYILDCRPYANAVGNRAKGAGWEILNNYPGCTLEFLNIANIHSMRHSLWKIKDAAVSSIDKEDGWFNQLESSGWFGHIKLVIQGATRLAKLI
. |.. ..||..|.||  ||. |.|.| |.|  .||  . ..|..| ||| ||.|| |. ...  .  .   ... ||||||. ||| |.. .. .|| .
kanpnsellyvvdtrpklnalankaagkGyenednysnikfqfvgienihvmreslqkllevvelksksvseflsglessgwlkhikavldasifiakav

HLQHHNVLVHCSDGWDRTSQLVSLAELLLDPYFRTIRGFQILIEKEWLSFGHKFAQRCGQVHgKDESEQSPILYQFIEACYQIIHQFPSKFEFNANFLKT
. ....||||||||||||.| .|||.||||||.|||.||..||||||||||||| .|||... .|. | |||. ||.|. .|...|||  |||| .|| .
aeegasvlvhcsdGwdrtaqvcslasllldpyyrtikGflvliekewlsfGhkfsercGlld.edskevsPiftqflecvwqlleqfpkafefnerflle

ILYHSYSGKYGNFLFNTEKERVQNHIYGKTISLWAEMDGNLKEYINPLYQPTgiKERDVIFPDCSIKRFKVWKQLYF
.  | || ..|.|| |.||.| ....  .| |||| .  . ..|.||||...  .|..|. || . ...|.|. || 
lhdhvyscqfGtflgncekdrrdlklkertkslwayllerkddylnplykae..tekevlkpdtapaalklwralyn
subfamily_Ank-MTMR1_pd Subfamily Ank-MTMR1 618-893 4.4e-85 277.9 In-house 125-402 (405) alignment 
Range on Protein: 618-893
Range on HMM: 125-402/405.0
NNSSDRTLYILDCRPYANAVGNRAKGAGWEILNNYPGCTLEFLNIANIHSMRHSLWKIKDAAVSSI-DKED------GWFNQLESSGWFGHIKLVIQGAT
  .  .|||..|.||  ||. | |.|||.| . ||| | | |.|| ||| .|.|| |.  |  ||  ||.        ..  .| .||  ||| ... ||
lsapsktlylidarpklnaiantangagfenihnypncklvfmnipnihvirksleklvlamkssardkdhtestdmrfwgyieetgwishiksileaat

RLAKLIhLQHHNVLVHCSDGWDRTSQLVSLAELLLDPYFRTIRGFQILIEKEWLSFGHKFAQRCGQVHGKDEsEQSPILYQFIEACYQIIHQFPSKFEFN
  |.|| |.   .||||||||||| |. ||...|||||.||| |||.|||||||||||||. | |.. |..| |.|||. ||...|.|.. |||  ||| 
fsaeli.lkgnsilvhcsdgwdrtpqitsltqilldpyyrtivgfqvliekewlsfghkfslrlghlpgnee.erspifqqfldccfqllsqfpllfeft

ANFLKTILYHSYSGKYGNFLFNTEKERVQNHIYGKTISLWAEMDGNLKEYINPLYQPTGIKErdvIFPDCSIKRFKVWKQLYF
 ..|  |    .| ||| || | ||.|||...  ||||.|.|.. |.. ..|| |.|  |.    | |    . ...||  |.
pslllfisdnihsckygtflnncekdrvqdqvktktisiwsevnlnvnkflnpyynpqdiqs...ikpklysrclelwkacym
subfamily_MTMR9_pd Subfamily MTMR9 626-894 2.5e-68 222.9 In-house 123-391 (393) alignment 
Range on Protein: 626-894
Range on HMM: 123-391/393.0
YILDCRPYANAVGNRAKGAGWEILNNYPGCTLEFLNIANIHSMRHSLWKIKDAAVSSIDKEDGWFNQLESSGWFGHIKLVIQGATRLAKLIHLQHHNVLV
.|.| |    |  .|.||.| |  ..|.  . .  ......|.  || |. .|      . | ....||.|||. ... ... |. .|.... ..  |.|
livdtrsksaaenarskgggietevkysqwkkasrslesvasiqdslaklleacsdaglstdkflsrleksgwlsqvadlleaalvvaqcldeegapvvv

HCSDGWDRTSQLVSLAELLLDPYFRTIRGFQILIEKEWLSFGHKFAQRCGQVHGKD--ESEQSPILYQFIEACYQIIHQFPSKFEFNANFLKTILYHSYS
| ..| | | |..||| |.|||..||.|||. |||.||.  || ||.|. .|  |.  . ...|.   |... |||..||| .||||...| ..  ||||
hgeeGlDatlqvtsLaqlildpdaRtvrgfealiereWiqaGHPFasRaskvaaketkkklsgpvfllFLDcvyqilsqfpasFEFneelLillfehsys

GKYGNFLFNTEKERVQNHIYGKTISLWA--EMDGNLKEYINPLYQPtgikERDVIFPDCSIKRFKVWKQLYFN
 ..|.|| ..|.|| ....  ||.|||.  . . .||...||||..    ...|| |    . ...|..||..
sqfgtflcdneaerkelklkkktvslwsyvnrpeklkqflnplyea....naeviwpsvapqslelWselylr
subfamily_MTMR5_pd Subfamily MTMR5 652-889 2.7e-58 190.0 In-house 225-476 (483) alignment 
Range on Protein: 652-889
Range on HMM: 225-476/483.0
YPGCTLEFLNIANIHSMRHSLWKIKDAAVSSIDKED----GWFNQLESSGWFGHIKLVIQGATRLAKLIHLQHHNVLVHCSDGWDRTSQLVSLAELLLDP
.  . .  ... .|  .. |. |.  | ..| . |.     . ...| | |.  |. ..| .. ...|. ||   |||   |||| |.|..|||.|||||
dskaefipvelveirqvkasfkkllraClpstaveeaesqsFlksvedseWlqqissllqlsgavvdlldlqgssvlvslEdGwdvtaqvsslaqllldp

YFRTIRGFQILIEKEWLSFGHKFAQRCGQVHGKDESEQSPILYQFIEACYQIIHQFPSKFEFNANFLKTILYHSYSGKYGNFLFNTEKERVQNHI-YG--
|.||. ||..|.|||||.|||.|..|. |.. . .|  .|.  ||... .|. .||| .||||  .||.. ||| | ..  ||...|.||... . |   
yYRtleGFkvLveKEWLafGHrFtkrsnqtlsaqssgfaPvFlqFLDcvhqvsrqfPlafefndfylkflayhsvsnrfrtfllDseyerlesgllyeek

-------KTISLWAEMDGNLKE---YINPLYQPtgiKERDVIFPDCSIKRFKVWK
        ..|.|  .| . |    . | ||.|   .|. |. | ...  .|||.
aekrakkagksvwdyidrqhkrspifynflysp...desevlrPssnvsslkvWd
subfamily_MTMR10_pd Subfamily MTMR10 680-842 1.5e-41 134.5 In-house 146-307 (380) alignment 
Range on Protein: 680-842
Range on HMM: 146-307/380.0
VSSIDKEDGWFNQLESSGWFGHIKLVIQGATRLAKLIHLQHHNVLVHCSDGWDRTSQLVSLAELLLDPYFRTIRGFQILIEKEWLSFGHKFAQRCGQVHG
   .. .|.|. .||...|   ..|... |. ..|... ....|..  |.| |    . ||| |.|||..|||.||| ||.||| . ||.| .|.|..  
eefvtlddkwlssLektrWLayvrlclstasdavktvvekkrsvilqesegrDlscvvaSLaqlmldphyrtisGfqsliqkewvaaghpfldrlghikp

KDESEQsPILYQFIEACYQIIHQFPSKFEFNANFLKTILYHSYSGKYGNFLFNTEKERVQNHI
...||. |.   | .  .| ..||||.|||.  || ... .|.|| ...||||.|..|...  
sekses.pvfllFldcvdqlleqfpseFeFtetfLialwdsshsgifltflfnseeqrlkavv
subfamily_MTMR1_pd Subfamily MTMR1 492-597 8.8e-34 109.4 In-house 6-112 (389) alignment 
Range on Protein: 492-597
Range on HMM: 6-112/389.0
GWTLYSARDEYARMGVPSP-DWRVSDANYNYFICDSYPGLMGVPESITDEQLKSVAQFRSKGRIPVLSYRHWSNKCSITRCSQPMVGIGGNRSTEDENLL
||..|..  |. |.|...   ||... | .| .||.|| .. ||....||.|| ||.||||||.||||. . .|...|.|.|||.||. |.||.|||..|
GWkvydpeaelerlgllneklWritklnkkyelcdtYpavlvvpkvvsdedlkkvaafrskgRlPvlswlnkenqavilrasqplvGlsgkrskedekyl

NSIRMTS
. |. . 
qailean
subfamily_MTMR6_pd Subfamily MTMR6 488-598 2.5e-33 107.9 In-house 14-123 (397) alignment 
Range on Protein: 488-598
Range on HMM: 14-123/397.0
LVGLGWTLYSARDEYARMGVPSPDWRVSDANYNYFICDSYPGLMGVPESITDEQLKSVAQFRSKGRIPVLSYRHWSNKCSITRCSQPMVGIGGnRSTEDE
    ||.|.. . ||.|||||.  | ..|.| .| .||.||  . ||.|.| |.| . ..||||||.||||| | .|. .| |||||. |.   |..|||
ekvsGwklldlkaeytrmgvpnekwtltdlnkdyelcdtyprelyvPksatkevlvgsskfrskgrlPvlsylhkeneaaicrcsqplsgfsa.rclede

NLLNSIRMTST
.||. || . .
klleairkanp
subfamily_MTMR9_pd Subfamily MTMR9 490-597 5e-32 103.4 In-house 12-119 (393) alignment 
Range on Protein: 490-597
Range on HMM: 12-119/393.0
GLGWTLYSARDEYARMGVPSPDWRVSDANYNYFICDSYPGLMGVPESITDEQLKSVAQFRSKGRIPVLSYRHWSNKCSITRCSQPMVGIGGNRSTEDENL
  |.. ..   |.|.. ..|..||.|. | |. .| |||  . ||..|.||.|| .|.||..||.|||||.|  .|  . |.|||..|  | |  |||.|
edgysafdrenefaklisasdewRissvNknfkvcasypesvivPkaiddeelkasaafreggrfPvLsylhketkavllrssqplcgssgkrckedekl

LNSIRMTS
||..  ..
lnlvlkkl
subfamily_pats1_pd Subfamily pats1 653-775 1.9e-23 74.7 In-house 334-458 (691) alignment 
Range on Protein: 653-775
Range on HMM: 334-458/691.0
PGCTLEFLNIANIHSMRHSLWKIKDAaVSSIDKEDGWFNQLESSGWFGHIKLVIQGATRLAKLIHLQHHNVLVHCSDGWDRTSQL---VSLAELLLDPYF
 .. ..||..   . ..   ... .. . |.|  |  ....| | |   .||....| ....|.   .  .|   .|. . . .|    ||| .|.||..
issniiflslPtrekveerffdllqs.ilsldgsddewkeieeskwvdsvkllleaavkvsnlldeGssvllknsidsPlieldlasisslaqvlsdPfy

RTIRGFQILIEKEWLSFGHKFAQRCG
||. ||..||||||||.|. |.... 
rtldGfkvliekewlsyGfPfskiny
subfamily_Ank-MTMR1_pd Subfamily Ank-MTMR1 492-597 3.2e-22 70.8 In-house 15-127 (405) alignment 
Range on Protein: 492-597
Range on HMM: 15-127/405.0
GWTLYSARDEYARMGVPS-------PDWRVSDANYNYFICDSYPGLMGVPESITDEQLKSVAQFRSKGRIPVLSYRHWSNKCSITRCSQPMVGIGGNRST
|| .|  . ||.|. .           |.|.. | .| .| ||.  . | .  .| .|. .  |||||||| ||..  | ..||.|||||.|||  .|  
gwevynqkkeylrfniyideenssncywkvtsinkeykmcssyssslvvlskaldkdlekifsfrskgripslswkdpssnasisrcsqplvgierarcp

EDENLLNSIRMTS
|||    |. ...
edelycsslalsa
subfamily_pats1_pd Subfamily pats1 785-868 1.4e-21 68.5 In-house 552-635 (691) alignment 
Range on Protein: 785-868
Range on HMM: 552-635/691.0
QSPILYQFIEACYQIIHQFPSKFEFNANFLKTILYHSYSGKYGNFLFNTEKERVQNHIYGKTISLWAEMDGNLKEYINPLYQPT
 |||. ||... .|. ..||  ||||  .| ... .|.|...||||..  |........ .. |.|. .. |   .|| ||...
fsPifvqfldlvwqlqkefPfhfefneslllllvkesfssrfGnflyseakrdserkvlkrsksiwsfinqnksrfinllykhs
subfamily_MTMR5_pd Subfamily MTMR5 501-574 6.6e-16 50.2 In-house 13-93 (483) alignment 
Range on Protein: 501-574
Range on HMM: 13-93/483.0
EYARMGVP-------SPDWRVSDANYNYFICDSYPGLMGVPESITDEQLKSVAQFRSKGRIPVLSYRHWSNKCSITRCSQP
.| |.|.        . ..|.| .|..| .|.|||.|. ||... |.... ||.   ..|.||  .||  ||  . | ...
dykRlGlgalngaskrgkfrisevNkkytvcrsYPalivvPsevsddsiarvakcfrqnRlPvvtWrhernkalLiRsggf
subfamily_pats1_pd Subfamily pats1 493-573 1e-09 29.4 In-house 6-88 (691) alignment 
Range on Protein: 493-573
Range on HMM: 6-88/691.0
WTLYSARDEYARMGVPSP-DWRVSDAnYNYFICDSYPGLMGVPESITDEQLKSVAQFRSKgRIPVLSYRHWSNKCSITRC---SQ
.  ||   |. |...    |||| .   .  ... ||  . ||....|| |.| .. ||  .|||||. . .|| |. |     |
fdiyslliegqrlkldldkdwrvvef.lsrdlseiyPkrilvPklvsdellvsyvrkrss.kiPvlswsnqnnksslfricvynq
0045098 (Phosphotyrosine protein) phosphatases II 694-773 9.8e-08 27.2 In-house 174-270 (278) alignment 
Range on Protein: 694-773
Range on HMM: 174-270/278.0
ESSGWFGHIKLVIQGATRLAKLIHL------QHHNVLVHCSDGWDRTSQLVSlAELLLDP------------YFRTIRGFQILIEKEWLSFGHKFAQR
 .. .. ... . .   .||.|. .      ... |||||| |..||  ||  | |.|.             ..|. |.....  .|.. | ..|...
ilksflellefirealkllaslllsslllldsggpvlVHCsaGvgRtGtlva.aylmlelleggvdlleavkelrsqRpglavqnleqyrflyeflle
PTPc_DSPc_SM00012 717-751 3.3e-07 25.8 In-house 38-70 (105) alignment 
Range on Protein: 717-751
Range on HMM: 38-70/105.0
HlqHHNVLVHCSDGWDRTSQLVSLAELLLDPYFRT
.  ...|.||||.|..|| ..| |. || . . .|
s..skpvvVhCsaGvgRtgtfvaldillqqleket
subfamily_MTMR14_pd Subfamily MTMR14 716-775 1.4e-06 19.4 In-house 261-329 (357) alignment 
Range on Protein: 716-775
Range on HMM: 261-329/357.0
IHLQH---HNVLVHCSDGWDRTSQLVSLAELLL--DP-YFRTIRGFQIL---IEKEWLSFGHKFAQRCG
 ....     .||||  |||||   |||  | |  |    ....  ..|   .  .|. |||....|  
kyvkededsGllvhcisGWdrtPlfvsllrlslWadglihqslsaaellyltvaydWflfghqlpdrlk
0051082 (Phosphotyrosine protein) phosphatases II 712-745 7.6e-06 21.1 In-house 84-117 (151) alignment 
Range on Protein: 712-745
Range on HMM: 84-117/151.0
LAKLIHLQHHNVLVHCSDGWDRTSQLVSLAELLL
| .|.. ....|||||| |..||  || |  .||
lellldkkngpvlvHCsaGkgRTGtlvalylmll
0049772 (Phosphotyrosine protein) phosphatases II 711-745 8.8e-06 21.1 In-house 201-237 (314) alignment 
Range on Protein: 711-745
Range on HMM: 201-237/314.0
RLAKLIHL--QHHNVLVHCSDGWDRTSQLVSLAELLL
.. ..|.   ....|||||..|..||  .| .| |..
eflefieeadkggpvlvHCkaGkgRtgtfvvaaylmk
GRAM GRAM domain 382-421 9.8e-06 16.4 Pfam-A 29-68 (69) alignment 
Range on Protein: 382-421
Range on HMM: 29-68/69.0
FIKGSLYLTNFQIIFYGYTTKNEPYVKHFSLHTISKLTKN
. .| |||||  .||..  .. . .|  . | .|... |.
pvqGrlYlTnyrliFrSdklddskvvvvipladikrveks