Gene DDB_G0288731 in Dictyostelium discoideum

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family Myotubularin
Subfamily DdisMTMR1-like
Protein sequence
ID Type Fasta BLAST phosphatome Note
DdisP028_AA protein Get Run
DdisP028_AA_809-1223 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_Dicty-MTMR1-like_pd Subfamily Dicty-MTMR1-like 798-1222 1.1e-176 580.0 In-house 2-404 (404) alignment 
Range on Protein: 798-1222
Range on HMM: 2-404/404.0
CFKNEEILGG-YDGWNIYQALKEFARQSIPNE-DWRVSHYNNDYQFSPTYPNLLIVPKRITDQELINTTSFRSKGRIPTLVWKSPNSNSVITRCSQPVIG
.|...|  .   |||.||.| .|..|..|..| .||.|..|.||....|||.||.||..|.|.|| ...|||||||||.|.|.....||.|||.|||..|
afsysekksvledgwliydaeeEykRlgikseseWriskinsdyelcetYPkllvvPesisDeelkkvasfRskgRiPvlswrhrsknstitRssqplvG

VTKKRSLDDEKLIESILLANPQSEKVYIMDARPQLNAVANQMMGLGYEDTNNqsYNNCILKFLNIENIHKMRHSQKKLFKSImsdsviY----Gennnnn
.||.|| .|||||.|| .|..|.|..||.||||..|||||...| ||||...  |.||...||||||||..|.|.|||.|..                  
ltksrseedEklinsirkaktqletlyildarpkanavansakgagyedisr..yenceieflnienihelreslkklkkav......nsiiek......

innnnsnngsggngnnnnlnSINILNLEESTRdWLEHIKSILIGTLDIVDIIQFYKSSVVVHCSDGWDRTSQLCSLAQLLLDPYYRTVIGFQVLIEKEWC
                    . |.|.  ||.| ||.|||..| |. .||..|. .||||.|||||||||||||.||.||||||||||. ||.|||||||.
....................eknwlselessr.WldhiklllegskriveliekekssvlvhcsdgwDrtsqlsslsqllldpyyrtiegFivliekewl

SFGHKFESRIGHtgKNEKKSDELSPIFLQFIDCVWQIMQQNPTSFQFNSKYLLEIIHHLYSCRFGTFLFDCQEKRVSANLMSKTTSIWSYINQNHSPYFN
||||||..|||.  ..||.||| |||||||||||.|...|.||||.||.|.|..|...||||||||||.|....|...||...|.|.|.....|.|.|.|
sfGhkfaqRigq..ttekssdersPiflqFidcvyqltkqfptsFeFnekflikildalyscrfgtFLydsekeRqqnnlaketvslWalleankseyln

KNYIYNSNEPPIRIDTSE---------LSLWSEYYLHWRN
..||....|   .|..||         ..|||||||.|||
plyilekkeqkenitssessssadikliklWseyylrwrn
0040695 (Phosphotyrosine protein) phosphatases II 808-1221 6.5e-129 423.8 In-house 5-386 (388) alignment 
Range on Protein: 808-1221
Range on HMM: 5-386/388.0
YDGWNIYQALKEFARQSIPNEDWRVSHYNNDYQFSPTYPNLLIVPKRITDQELINTTSFRSKGRIPTLVWKSPNSNSVITRCSQPVIGVTKKRSLDDEKL
..||..|  |.|. |. .... ||.|..|..|...|.|| ||.||| |.|..|..  .|||||||| |... ||...|..|.||| .|.. .|||.||||
eegwslydilrelkrlglgldlwrisivNenyelcpsYPallvVPksisdellkrvarfrskgriPvlsyrhpnngavllRssqplvglllsrsledekl

IESILLANPQSEKVYIMDARPQLNAVANQMMGLGYEDTNNqsYNNCILKFLNIENIHKMRHSQKKLFKSImsdsviYGENNNNNINNNNSnngsggngnn
.|.|| ..|...|..|.|.|| |||.||...| |.| ...  | |. | ||||.||| .| | .||.. .      ..  .  |...  .          
leailkllpnlskllivdlrpklnalanralgggveneda..ypnaeliflnipnihvvreslqklldac......lnvpdslnllslle..........

nnlnsinilnleesTRDWLEHIKSILIGTLDIVDIIQFYKSSVVVHCSDGWDRTSQLCSLAQLLLDPYYRTVIGFQVLIEKEWCSFGHKFESRIGHtGKN
                .||..||.|| ..  ||..... .|||.|||||||||||||.|||||||||||||. ||||||||||.|||||| .|.|| . .
..............esgwldliklilelavlivklldlgnssvlvhcsdgwdrtsqlssLaqllldPyYRTleGFqvLiekeWlsfghkfadRlgh.les

EKKSDELSPIFLQFIDCVWQIMQQNPTSFQFNSKYLLEIIHHLYSCRFGTFLFDCQEKRVSANLMSKTTSIWSYINQNHSPYFNKNYIYNSN-EPPIRID
|..|.| ||.||.|.|||||...|.||.|.||. .|| ...||||||||||||... .|. ......| |.|||.....| ..| .|  .|.      ..
eidskefsPvFllFLdcvwqLlrqfPtaFeFnerlLlfLadhlyscrfgtFlfnsekerlelsvsertlslwsyllsrkseflnplYdpsslevllpsls

TSELSLWSEYYLHWR
 ..| ||.||||.| 
vldlllWleyylrwl
Myotub-related Myotubularin-like phosphatase domain 807-1167 3.2e-126 413.8 Pfam-A 18-351 (353) alignment
Myotub-related Myotubularin-like phosphatase domain 807-1167 3.2e-126 413.8 In-house 18-351 (353) alignment
subfamily_Ank-MTMR1_pd Subfamily Ank-MTMR1 808-1217 1.2e-98 322.6 In-house 13-401 (405) alignment 
Range on Protein: 808-1217
Range on HMM: 13-401/405.0
YDGWNIYQALKEFARQSIP----NED---WRVSHYNNDYQFSPTYPNLLIVPKRITDQELINTTSFRSKGRIPTLVWKSPNSNSVITRCSQPVIGVTKKR
 |||..|.  ||..|  |     |.    |.|.  |..|..  .|.  |.| .. .|..| .  |||||||||.| || |.||. |.|||||..|. . |
idgwevynqkkeylrfniyideenssncywkvtsinkeykmcssyssslvvlskaldkdlekifsfrskgripslswkdpssnasisrcsqplvgierar

SLDDEKLIESILLANPqSEKVYIMDARPQLNAVANQMMGLGYEDTNNqsYNNCILKFLNIENIHKMRHSQKKLFKSIMSDSviygennnNNINNNNSNng
  .||    |. |. | |  .|..||||.|||.||   | |.|.  |  | || | |.|| ||| .|.| .||  .. | .         . .  .|   
cpedelycsslalsap.sktlylidarpklnaiantangagfenihn..ypncklvfmnipnihvirksleklvlamkssa........rdkdhtest..

sggngnnnNLNSINIlnLEEStrDWLEHIKSILIGTLDIVDIIqFYKSSVVVHCSDGWDRTSQLCSLAQLLLDPYYRTVIGFQVLIEKEWCSFGHKFESR
        ..    .  .||.   |. ||||||  .    ..| .   |..|||||||||| |. ||.|.||||||||. |||||||||| ||||||  |
........dmrfwgy..ieet..gwishiksileaatfsaeli.lkgnsilvhcsdgwdrtpqitsltqilldpyyrtivgfqvliekewlsfghkfslr

IGHTGKNEkksDELSPIFLQFIDCVWQIMQQNPTSFQFNSKYLLEIIHHLYSCRFGTFLFDCQEKRVSANLMSKTTSIWSYINQNHS----PYFNKNYIy
.||   ||   .| |||| ||.||..|...| |  |.|    || |   ..||..|||| .|.  ||  ..  ||.|||| .| |      ||.| . | 
lghlpgne...eerspifqqfldccfqllsqfpllfeftpslllfisdnihsckygtflnncekdrvqdqvktktisiwsevnlnvnkflnpyynpqdi.

NSNEPpiRIDTSELSLWSEYY
.| .|  .. .  | ||   |
qsikp..klysrclelwkacy
subfamily_MTMR1_pd Subfamily MTMR1 1018-1221 1.5e-87 286.4 In-house 185-387 (389) alignment 
Range on Protein: 1018-1221
Range on HMM: 185-387/389.0
LEEStrDWLEHIKSILIGTLDIVDIIQFYKSSVVVHCSDGWDRTSQLCSLAQLLLDPYYRTVIGFQVLIEKEWCSFGHKFESRIGHTGKNEkKSDELSPI
||..   ||||||.|| |.  ||. ..  |.||.||||||||||.|| |||.||||.||||. ||.|||||||.||||||..|.||..||. . .| ||.
lest..kWlehiklilagavkivekvetektsvlvhcsdGWDRtaqltsLamlllDsyyRtieGfevliekeWlsfGHkfkeRlghgdkns.sdaersPv

FLQFIDCVWQIMQQNPTSFQFNSKYLLEIIHHLYSCRFGTFLFDCQEKRVSANLMSKTTSIWSYINQNHSPYFNKNYIYNSNEPPIRI--DTSELSLWSE
||||||||||...| || |.||...|. .. |||||.||||||.....|| ... .||.|.|||.|.... ..|..|  . ..  .      ..| ||.|
FlqfiDcvwqltrqfptAFefneefLitlldhlysclfGtflfnsekervkekvkektvslwsyvnsskeeftnplyaeelekkvlypkaslrrlelWke

YYLHWR
||| | 
yylrwn
subfamily_MTMR6_pd Subfamily MTMR6 1017-1221 1.9e-78 256.5 In-house 195-396 (397) alignment 
Range on Protein: 1017-1221
Range on HMM: 195-396/397.0
NLEEStrDWLEHIKSILIGTLDIVDIIQFYKSSVVVHCSDGWDRTSQLCSLAQLLLDPYYRTVIGFQVLIEKEWCSFGHKFESRIGHTgknEKKSDELSP
 ||.|  .|| |||..|  .. |   ..  . ||.||||||||||.| ||||.|||||||||. ||.||||||| ||||||..| |.    ...| |.||
gless..gwlkhikavldasifiakavaeegasvlvhcsdGwdrtaqvcslasllldpyyrtikGflvliekewlsfGhkfsercGll...dedskevsP

IFLQFIDCVWQIMQQNPTSFQFNSKYLLEIIHHLYSCRFGTFLFDCQEKRVSANLMSKTTSIWSYINQNHSPYFNKNYIYNSNEPPIRIDT--SELSLWS
||.||..||||...| |..|.|| ..|||. .|.|||.||||| .|...|  ..|  .|.|.|.|. .... | |  |  ....  .. ||  ..|.||.
iftqflecvwqlleqfpkafefnerfllelhdhvyscqfGtflgncekdrrdlklkertkslwayllerkddylnplykaetekevlkpdtapaalklwr

EYYLHWR
  | .. 
alynrfd
subfamily_MTMR3_pd Subfamily MTMR3 1011-1219 1e-70 231.7 In-house 234-441 (442) alignment 
Range on Protein: 1011-1219
Range on HMM: 234-441/442.0
NSINILNLEESTrDWLEHIKSILIGTLDIVDIIQFYKSSVVVHCSDGWDRTSQLCSLAQLLLDPYYRTVIGFQVLIEKEWCSFGHKFESRIGHtGKNEKK
...|.|   |.|  ||...  .|  .. .|. ..  . .|.||||||||||.|. .||.|||||||||. ||.||.|.|| .|||||  |.|| |.| ..
desnwlsalekt.kWlqnlsvllkaavkvveavdkegrpvlvhCsdGWdrttqivalakllldpyyrtleGfkvlvereWldfGhkfadrcgh.genvdd

SDELSPIFLQFIDCVWQIMQQNPTSFQFNSKYLLEIIHHLYSCRFGTFLFDCQEKRVSANLMSKTTSIWSYINQNHSPYFNKNYIYNSNE-PPIRIDTSE
..| .|.|||..|.| |. .| ||||.||. .|. ...| ||| |||||......|   .. ..| |.||......  | |. |  ...      ..  |
anercPvflqwldavhqlqrqfPtsfefneaflvklvqhtysclfGtflansekereeekvkertlsvWsllrakekeyrnllykekteavllpavsvre

LSLWSEYYLH
|.|||| ||.
lklwsevyle
subfamily_MTMR9_pd Subfamily MTMR9 1023-1220 2.7e-59 193.2 In-house 193-392 (393) alignment 
Range on Protein: 1023-1220
Range on HMM: 193-392/393.0
RDWLEHIKSILIGTLDIVDIIQFYKSSVVVHCSDGWDRTSQLCSLAQLLLDPYYRTVIGFQVLIEKEWCSFGHKFESRIGHTGKNEKKSDELSPIFLQFI
  ||.... .|  .| ......  ...|||| ..| | | |. |||||.|||..||| ||. |||.||   || | ||  ... .|.|... .|.|| |.
sgwlsqvadlleaalvvaqcldeegapvvvhgeeGlDatlqvtsLaqlildpdaRtvrgfealiereWiqaGHPFasRaskvaaketkkklsgpvfllFL

DCVWQIMQQNPTSFQFNSKYLLEIIHHLYSCRFGTFLFDCQEKRVSANLMSKTTSIWSYINQNHSPYFNKNYIYNSNEPPIRI--DTSELSLWSEYYLHW
|||.||..| | || || ..|  . .| ||..||||| |....| ...| .||.|.|||.|...      | .|. |.  |.       |.|||| ||.|
DcvyqilsqfpasFEFneelLillfehsyssqfgtflcdneaerkelklkkktvslwsyvnrpeklkqflnplyeanaeviwpsvapqslelWselylrw
subfamily_MTMR5_pd Subfamily MTMR5 1018-1218 1.4e-58 190.9 In-house 270-479 (483) alignment 
Range on Protein: 1018-1218
Range on HMM: 270-479/483.0
LEEStrDWLEHIKSILIGTLDIVDIIQFYKSSVVVHCSDGWDRTSQLCSLAQLLLDPYYRTVIGFQVLIEKEWCSFGHKFESRIGHTGKNEKKsdELSPI
.|.|  .||. |.|.|  .  .||... ..|||.|   |||| |.|. |||||||||||||. ||.||.|||| .|||.|. |  .|  ...    ..|.
veds..eWlqqissllqlsgavvdlldlqgssvlvslEdGwdvtaqvsslaqllldpyYRtleGFkvLveKEWLafGHrFtkrsnqtlsaqss..gfaPv

FLQFIDCVWQIMQQNPTSFQFNSKYLLEIIHHLYSCRFGTFLFDCQEKRVSANLM----------SKTTSIWSYINQNH--SPYFNkNYIYNS-NEPPI-
||||.|||.|...| |..| ||. ||  . .|  |.|| |||.|....|. ..|.            ..|.| ||...|  || |  |..|.. ..  . 
FlqFLDcvhqvsrqfPlafefndfylkflayhsvsnrfrtfllDseyerlesgllyeekaekrakkagksvwdyidrqhkrspify.nflyspdesevlr

-RIDTSELSLWSeYYL
   ..|.|..|. |||
PssnvsslkvWd.yyl
subfamily_MTMR1_pd Subfamily MTMR1 808-979 1.2e-56 184.7 In-house 4-174 (389) alignment 
Range on Protein: 808-979
Range on HMM: 4-174/389.0
YDGWNIYQALKEFARQSIPNE-DWRVSHYNNDYQFSPTYPNLLIVPKRITDQELINTTSFRSKGRIPTLVWKSPNSNSVITRCSQPVIGVTKKRSLDDEK
 |||..|.. .|. |. ..||  ||... |..|....|||..|.||| ..|..| ....||||||.|.|.| ......||.|.|||. |...||| .|||
edGWkvydpeaelerlgllneklWritklnkkyelcdtYpavlvvpkvvsdedlkkvaafrskgRlPvlswlnkenqavilrasqplvGlsgkrskedek

LIESILLANPQSEKVYIMDARPQLNAVANQMMGLGYEDtnNQSYNNCILKFLNIENIHKMRHSQKKLFKSIMS
... || || ||||..|.|||.. |||||...| |||.  .. |.|. | ||.|.||| .|.| ||| . ...
ylqaileanaqsekllildarssvnavankakgkgyes..eeaYknaelifldihnihvvReslkklkelvlp
subfamily_MTMR6_pd Subfamily MTMR6 807-980 1.9e-54 177.5 In-house 15-185 (397) alignment 
Range on Protein: 807-980
Range on HMM: 15-185/397.0
GYDGWNIYQALKEFARQSIPNEDWRVSHYNNDYQFSPTYPNLLIVPKRITDQELINTTSFRSKGRIPTLVWKSPNSNSVITRCSQPVIGVTKkRSLDDEK
  .||. ..  .|..|. .||| | ....|.||.   |||. | |||..| . |. .. ||||||.| | .   . .. | |||||. |... |.|.|||
kvsGwklldlkaeytrmgvpnekwtltdlnkdyelcdtyprelyvPksatkevlvgsskfrskgrlPvlsylhkeneaaicrcsqplsgfsa.rcledek

LIESILLANPQSEKVYIMDARPQLNAVANQMMGLGYEDTNNqsYNNCILKFLNIENIHKMRHSQKKLFKSIMSD
|.| |  |||.|| .|..|.||.|||.||.  | |||...|  |.|. ..|..||||| ||.|..||.. .  .
lleairkanpnsellyvvdtrpklnalankaagkGyenedn..ysnikfqfvgienihvmreslqkllevvelk
subfamily_MTMR10_pd Subfamily MTMR10 1024-1194 8.3e-43 138.6 In-house 163-330 (380) alignment 
Range on Protein: 1024-1194
Range on HMM: 163-330/380.0
DWLEHIKSILIGTLDIVDIIQFYKSSVVVHCSDGWDRTSQLCSLAQLLLDPYYRTVIGFQVLIEKEWCSFGHKFESRIGHTGKNEKKSDelsPIFLQFID
 ||. .. .|  . |.|...   | ||..  |.| |    ..|||||.|||.|||  ||| ||.||| . ||.| .|.||. ..||..    |.|| | |
rWLayvrlclstasdavktvvekkrsvilqesegrDlscvvaSLaqlmldphyrtisGfqsliqkewvaaghpfldrlghikpsekses...pvfllFld

CVWQIMQQNPTSFQFNSKYLLEIIHHLYSCRFGTFLFDCQEKRVSANLMSKTTSIWSYINQNHSPYFNKNY
||.| ..| |..|.|. ..|. .  . .|. |.||||...|.|. |   |.   |  .  .... .... .
cvdqlleqfpseFeFtetfLialwdsshsgifltflfnseeqrlkavvsssplliakselkendllkdeld
subfamily_MTMR9_pd Subfamily MTMR9 809-980 1.2e-34 112.0 In-house 13-179 (393) alignment 
Range on Protein: 809-980
Range on HMM: 13-179/393.0
DGWNIYQALKEFARQSIPNEDWRVSHYNNDYQFSPTYPNLLIVPKRITDQELINTTSFRSKGRIPTLVWKSPNSNSVITRCSQPVIGVTKKRSLDDEKLI
||.. ..  .|||... . ..||.|. |....  ..||. .|||| |.|.||   ..||..||.| | .   . ..|. |.|||..| ..||  .||||.
dgysafdrenefaklisasdewRissvNknfkvcasypesvivPkaiddeelkasaafreggrfPvLsylhketkavllrssqplcgssgkrckedekll

ESILLANpqsEKVYIMDARPQLNAVANQMMGLGYEDTnnQSYNNCILKFLNIENIHKMRHSQKKLFKSIMSD
...| ..   .| .|.| | .  | ...  | | | .  ..| .   .  ..|.....  |  || ....  
nlvlkkl...kkGlivdtrsksaaenarskgggiete..vkysqwkkasrslesvasiqdslaklleacsda
subfamily_MTMR3_pd Subfamily MTMR3 817-914 4.9e-28 91.1 In-house 30-128 (442) alignment 
Range on Protein: 817-914
Range on HMM: 30-128/442.0
LKEFARQSI-PNEDWRVSHYNNDYQFSPTYPNLLIVPKRITDQELINTTSFRSKGRIPTLVWKSPNSNSVITRCSQPVIGVTKKRSLDDEKLIESILLA
 .|..|.    .| ||.|. |.|... ..||. ||||| |||..| ...|||| .|.|..||.  .. .|..||||| .|.   |. .||||...|  |
keeverlGfdlkeawrisdvnsdfklCssyPkklivPksitdddlkkvasfrslkrlPavvwrhkkngavlarcsqPevgwlgWrnaedekllkaiaka
subfamily_pats1_pd Subfamily pats1 1114-1200 2e-26 84.6 In-house 552-638 (691) alignment 
Range on Protein: 1114-1200
Range on HMM: 552-638/691.0
LSPIFLQFIDCVWQIMQQNPTSFQFNSKYLLEIIHHLYSCRFGTFLFDCQEKRVSANLMSKTTSIWSYINQNHSPYFNKNYIYNSNE
.||||.||.| |||. .. |. |.||  .|| .... .| |||.||..   ...  ...... ||||.||||.| . |  |   .. 
fsPifvqfldlvwqlqkefPfhfefneslllllvkesfssrfGnflyseakrdserkvlkrsksiwsfinqnksrfinllykhsass
subfamily_pats1_pd Subfamily pats1 1024-1108 1.4e-19 62.0 In-house 377-464 (691) alignment 
Range on Protein: 1024-1108
Range on HMM: 377-464/691.0
DWLEHIKSILIGTLDIVDIIQFYKSSVVVHCSDGWDRTSQL---CSLAQLLLDPYYRTVIGFQVLIEKEWCSFGHKFESRIGHTGKNE
 |.. .| .| .....   .   .| ..   .|. . . .|    ||||.|.||.|||. ||.||||||| |.|. |. .  |  ...
kwvdsvkllleaavkvsnlldeGssvllknsidsPlieldlasisslaqvlsdPfyrtldGfkvliekewlsyGfPfskinyhkesdd
subfamily_MTMR5_pd Subfamily MTMR5 826-955 1.2e-15 49.3 In-house 27-170 (483) alignment 
Range on Protein: 826-955
Range on HMM: 27-170/483.0
PNEDWRVSHYNNDYQFSPTYPNLLIVPKRITDQELINTTSFRSKGRIPTLVWKSPNSNSVITRCSQP----VIGVTKKR---------------SLDDEK
 ....|.|. |..|. . .||.|..||... |...   .    ..|.|  .|... ..... | ...    |.|. |.                ||. ||
krgkfrisevNkkytvcrsYPalivvPsevsddsiarvakcfrqnRlPvvtWrhernkalLiRsggfeskgvvgllksantqgsstsessessksleqek

LIESILLANPQSEKVYIMdarPQLNAVANQMMGLGYEDTNNQSYNNciL
... .. . ...... .     .|... .....   .|....  ..   
ylkavvnevsklsalaln...sslevslsvlasssssdkraalste..k
PH PH domain 318-479 2.6e-13 40.4 Pfam-A 3-102 (104) alignment 
Range on Protein: 318-479
Range on HMM: 3-102/104.0
KEGFLYLLKpqskyssllNSKKQWIKVYCIATNSNLFYWKNRE-QPYAEARGVIQLCHCSTRIMTKQDKkciqlnensnntsnsgdnskylltnskghks
|||.|.  .         ...|.| |.|.. |...|.|.|... . |.. .|.|.|  |. .. .....                               
keGyllkks.........ellktwkkryfvLtsnyLlyfksskkksykapkgsiplndctvkkasstkf...............................

fshkinpndiyNninnvnnnnnsaNNNNNNNNNN-----NnvdsnEVYYLSADSDVILEQWVETIEKE
                        .....||        .     | |.|||.|.  ...||. ... 
...........g............aqkesnnyfeitfknv.....esyllsaeseeerkrWvqalknl
PTPc_DSPc_SM00012 1014-1149 3e-13 45.2 In-house 21-103 (105) alignment 
Range on Protein: 1014-1149
Range on HMM: 21-103/105.0
NILNLEESTRDWLEHIKSiligtldivdiiqfyKSSVVVHCSDGWDRTSQLCSLAQLLLDPYYRTvigfqvliekewcsfghkfesrightgknekksde
.||.| ...... ....|               ...||||||.|..|| ... |. || . ...|                                   
silellravkknknkses...............skpvvVhCsaGvgRtgtfvaldillqqleket...................................

lspIFLQFIDCVWQIMQQNPTSFQFNSKYLLEIIHH
    .... ..|.....| |...|.. .||  .  .
...kevdifqivkelrkqRpgmvqteeqylflyral
PX PX domain 253-304 1.8e-10 27.1 Pfam-A 58-112 (113) alignment 
Range on Protein: 253-304
Range on HMM: 58-112/113.0
IQSFEFPSKKLIGN---MNPNFIKNRKEQLEKFLQLIASSQVAKLSRNLKVFLDP
..  ..|.|.|.|.   ....||. |...||..|| ..| ..   |..|. ||..
lklPplPkkvlfgsvrkkdeefiekrrkgLeeyLqrllshpelrksevltsFLev
PX PX domain 123-184 1.4e-09 24.2 Pfam-A 7-59 (113) alignment 
Range on Protein: 123-184
Range on HMM: 7-59/113.0
HITSTETVVQRKKSYTVYVIRVKSDQHQWEVVRRYKHFRVFSIQINNEVFnsnsssstpSST
...  ||   .|.||... ...|.....|.| |||..|  .  |. .. .         ...
svleretkgskkhsyylievelktgakewtvkRrYsdFeeLhsqLlrkfp.........rlk
subfamily_pats1_pd Subfamily pats1 810-889 2e-09 28.4 In-house 5-83 (691) alignment 
Range on Protein: 810-889
Range on HMM: 5-83/691.0
GWNIYQALKEFARQSIPNE-DWRVSHYNNdYQFSPTYPNLLIVPKRITDqELINTTSFRSKGRIPTLVWKSPNSNSVITRC
 ..||  |.|. |  .  . |||| .. .  . |  ||.  .||| ..| ||. .   . . .|| | |  .|  |.. | 
ifdiyslliegqrlkldldkdwrvvefls.rdlseiyPkrilvPklvsd.ellvsyvrkrsskiPvlswsnqnnksslfri
subfamily_MTMR3_pd Subfamily MTMR3 917-974 4e-09 28.7 In-house 171-226 (442) alignment 
Range on Protein: 917-974
Range on HMM: 171-226/442.0
QSEKVYIMDARPQLNAVANQMMGLGYEDTnnQSYNNCILKFLNIENIHKMRHSQKKLF
...|. |.|||    |.||.  | |.| .  . |.|| ..||.. ||| .|.| ..| 
ekkkllivdarsytaafanrakgGGcele..eyypncevvflglanihavrksfnslr
subfamily_MTMR10_pd Subfamily MTMR10 822-931 2.7e-08 25.0 In-house 18-124 (380) alignment 
Range on Protein: 822-931
Range on HMM: 18-124/380.0
RQSIPNEDWRVSHYNNDYQFSPTYPNLLIVPKRITDQELINTTSFRSKGRIPTLVWKSPNSNSVItRCSQPVigVTKKRSL-DDEKLIESILLANPQSeK
...  .. ..|.  |.  .  .|.|. ..||....|... .      ..| | .||. ....... |.|.     ...  . . ||  |..  ..|.  .
ekktvsdaivvllknelfaaaqtlPqyfvvpnslsdsdverlsrhykesRfplwvwshakgaall.rlsalq..eaesadkekeekmlelvrkchpan.d

VYIMDARPQLN
| ..|   .|.
vklvdlsdelp
0045098 (Phosphotyrosine protein) phosphatases II 1034-1072 7.1e-06 21.1 In-house 176-231 (278) alignment 
Range on Protein: 1034-1072
Range on HMM: 176-231/278.0
IGTLDIVDIIQF-----------------YKSSVVVHCSDGWDRTSQLCSLAQLLL
   |.... |.                   .  |.|||| |..||  |. .  .| 
ksflellefirealkllaslllsslllldsggpvlVHCsaGvgRtGtlvaaylmle
subfamily_LRR-DSP_pd Subfamily LRR-DSP 510-612 8.3e-06 19.1 In-house 22-128 (263) alignment 
Range on Protein: 510-612
Range on HMM: 22-128/263.0
QKYDSSILNIENDYINANNNNNNNNNNNNNNNNNNNNNNNNNNNANKLNVRKSIKKLYKDDDIIEEIEEE-FKNNDS--ETSKEYKLLESVLT-NSKCKD
| |    ..  .. ||. || |.|||..||.||||||||.||||.|| |. . |.    .   .  ..|   ..|        ||| .||..|  |   |
qsysdidideydenintcnninsnnndsnnsnnnnnnnndnnnncnknnileminsteleggglgclkelnirdnrelislpveykqveslitlvssvPd

LLIDPNY
..||  .
eiidklf